gene_oid	gene_length	percent_identity	query_start	query_end	subj_start	subj_end	evalue	bit_score	cog_id	cog_name	cog_length
649658179	446	46.82	2	440	1	407	2.0e-125	442	COG0593	Chromosomal replication initiation ATPase DnaA	408
649658180	376	38.73	1	376	1	364	9.0e-75	274	COG0592	DNA polymerase III sliding clamp (beta) subunit, PCNA homolog	364
649658181	824	62.17	14	579	2	559	0.0e+00	860	COG0187	DNA gyrase/topoisomerase IV, subunit B	635
649658182	820	59.8	2	809	3	802	0.0e+00	1016	COG0188	DNA gyrase/topoisomerase IV, subunit A	804
649658185	159	60.81	12	159	6	152	2.0e-53	201	COG0691	tmRNA-binding protein	153
649658186	148	38.46	14	143	17	137	8.0e-09	53.1	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
649658187	285	30.6	1	232	2	231	2.0e-21	96.9	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
649658188	294	41.96	9	291	2	276	3.0e-60	225	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
649658189	213	46.73	1	213	1	214	3.0e-61	228	COG2761	Predicted dithiol-disulfide isomerase, DsbA family	225
649658192	368	41.35	3	104	2	105	7.0e-17	81.9	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
649658196	246	26.67	10	244	6	231	6.0e-30	124	COG1018	Ferredoxin-NADP reductase	266
649658200	514	20.7	23	510	1	454	7.0e-29	122	COG0277	FAD/FMN-containing dehydrogenase	459
649658201	376	42.51	12	374	3	366	3.0e-113	401	COG1062	Zn-dependent alcohol dehydrogenase	366
649658203	213	55.87	1	213	1	211	6.0e-74	270	COG2910	Putative NADH-flavin reductase	211
649658204	439	44.01	15	418	4	405	6.0e-112	398	COG1252	NADH dehydrogenase, FAD-containing subunit	405
649658206	161	30.26	1	70	2	77	2.0e-06	45.2	COG1669	Predicted nucleotidyltransferase	97
649658207	693	43.47	159	692	2	549	2.0e-129	456	COG3604	Transcriptional regulator containing GAF, AAA-type ATPase, and DNA-binding Fis domains	550
649658208	146	17.91	9	142	19	149	1.0e-03	36.1	COG3678	Periplasmic protein refolding chaperone Spy/CpxP family	160
649658210	659	39.67	344	646	4	291	9.0e-71	261	COG1131	ABC-type multidrug transport system, ATPase component	293
649658211	376	25.69	158	375	67	284	3.0e-18	86.5	COG0842	ABC-type multidrug transport system, permease component	286
649658212	384	29.95	167	382	67	282	5.0e-18	85.7	COG0842	ABC-type multidrug transport system, permease component	286
649658214	168	36.5	9	145	12	139	5.0e-11	60.8	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
649658220	258	28.93	20	257	1	213	3.0e-31	129	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
649658221	795	37.4	35	760	8	748	0.0e+00	622	COG1554	Trehalose and maltose hydrolase (possible phosphorylase)	772
649658222	141	33.8	5	140	4	143	2.0e-18	85	COG1764	Organic hydroperoxide reductase OsmC/OhrA	143
649658223	232	35.16	11	226	4	221	3.0e-32	132	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
649658224	191	40.7	22	189	6	177	9.0e-29	119	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
649658225	201	27.96	9	187	3	202	4.0e-15	75	COG0778	Nitroreductase	207
649658227	260	46	21	259	3	251	1.0e-43	170	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
649658228	127	34.38	1	126	2	128	1.0e-17	81.9	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
649658229	225	35.98	4	206	65	277	4.0e-42	164	COG0122	3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase	285
649658230	291	21.86	100	284	18	230	2.0e-09	56.8	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
649658232	116	44.83	5	116	10	124	5.0e-27	112	COG2351	5-hydroxyisourate hydrolase (purine catabolism), transthyretin-related family	124
649658233	304	33.11	1	291	1	289	8.0e-39	154	COG0583	DNA-binding transcriptional regulator, LysR family	297
649658235	357	36.03	13	344	9	353	2.0e-70	259	COG1858	Cytochrome c peroxidase	364
649658237	316	28.29	1	199	3	207	4.0e-30	125	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
649658241	113	59.43	5	109	1	106	1.0e-23	101	COG1742	Uncharacterized inner membrane protein YnfA, drug/metabolite transporter superfamily	109
649658242	135	38.94	8	117	1	113	1.0e-16	79	COG0789	DNA-binding transcriptional regulator, MerR family	124
649658244	94	44.78	24	90	4	70	7.0e-11	58.9	COG2608	Copper chaperone CopZ	71
649658248	462	32.77	14	250	1	222	2.0e-32	133	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
649658263	763	37.21	321	762	38	509	3.0e-113	403	COG3378	Phage- or plasmid-associated DNA primase	517
649658267	469	22.15	166	444	6	272	5.0e-30	125	COG0863	DNA modification methylase	302
649658268	413	26.22	158	413	2	284	2.0e-38	153	COG0863	DNA modification methylase	302
649658274	652	34.78	3	627	1	596	0.0e+00	505	COG5525	Phage terminase, large subunit GpA	611
649658278	495	34.74	3	493	12	492	7.0e-117	414	COG5511	Bacteriophage capsid protein	492
649658279	404	27.17	1	275	4	275	2.0e-43	169	COG0616	Periplasmic serine protease, ClpP class	317
649658298	166	35.85	11	166	3	152	4.0e-22	97.7	COG3772	Phage-related lysozyme (muramidase), GH24 family	152
649658303	987	19.74	205	828	88	723	1.0e-36	148	COG1743	Adenine-specific DNA methylase, contains a Zn-ribbon domain	875
649658306	64	33.87	1	62	1	62	4.0e-03	33.1	COG4877	Uncharacterized protein	63
649658307	95	19.35	7	68	5	66	9.0e-03	31.9	COG2161	Antitoxin component YafN of the YafNO toxin-antitoxin module, PHD/YefM family	86
649658308	113	31.31	10	108	4	98	5.0e-08	49.7	COG3668	Plasmid stabilization system protein ParE	98
649658311	389	15.52	6	379	3	382	4.0e-09	56.2	COG0732	Restriction endonuclease S subunit	391
649658312	337	36.25	104	259	1	159	5.0e-26	111	COG4804	Predicted nuclease of restriction endonuclease-like (RecB) superfamily,  DUF1016 family	159
649658313	647	26.56	14	441	1	381	3.0e-40	160	COG0286	Type I restriction-modification system, DNA methylase subunit	489
649658314	187	36.56	9	187	26	203	3.0e-32	131	COG5514	Uncharacterized protein	203
649658317	598	26.64	8	587	19	601	1.0e-69	257	COG3387	Glucoamylase (glucan-1,4-alpha-glucosidase), GH15 family	612
649658318	743	37.24	242	724	1	479	5.0e-129	455	COG0380	Trehalose-6-phosphate synthase	486
649658319	257	30.45	23	256	20	260	2.0e-24	106	COG1877	Trehalose-6-phosphatase	266
649658320	161	20.81	1	143	4	147	2.0e-12	65.3	COG2110	O-acetyl-ADP-ribose deacetylase (regulator of RNase III), contains Macro domain	179
649658321	277	34.5	3	260	17	269	4.0e-73	268	COG2326	Polyphosphate kinase 2, PPK2 family	270
649658329	115	38.78	13	109	1	97	5.0e-20	89.6	COG2154	Pterin-4a-carbinolamine dehydratase	101
649658331	621	18.25	84	475	28	430	6.0e-21	96.2	COG1032	Radical SAM superfamily enzyme YgiQ, UPF0313 family	490
649658332	110	30.77	10	100	21	111	5.0e-12	63.1	COG0599	Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family	124
649658334	273	44.36	15	267	4	260	2.0e-65	242	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
649658337	308	45.02	1	288	1	291	1.0e-95	343	COG0774	UDP-3-O-acyl-N-acetylglucosamine deacetylase	300
649658338	223	48.15	4	219	1	211	6.0e-59	220	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
649658340	137	55.47	1	137	18	154	1.0e-40	158	COG1327	Transcriptional regulator NrdR, contains Zn-ribbon and ATP-cone domains	156
649658341	425	62.95	7	418	3	413	0.0e+00	624	COG0112	Glycine/serine hydroxymethyltransferase	413
649658342	161	43.92	1	148	1	148	2.0e-31	127	COG0359	Ribosomal protein L9	148
649658345	480	21.41	144	441	15	273	4.0e-04	39.8	COG4974	Site-specific recombinase XerD	300
649658355	204	37.07	6	201	1	199	4.0e-28	117	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
649658360	460	30.31	6	454	1	411	2.0e-57	216	COG2124	Cytochrome P450	411
649658361	182	18.37	35	177	17	158	5.0e-09	54.5	COG1580	Flagellar basal body-associated protein FliL	159
649658362	137	24.58	6	122	10	127	7.0e-10	56.4	COG3011	Predicted thiol-disulfide oxidoreductase YuxK, DCC family	137
649658363	367	25	67	174	2	109	3.0e-11	62.8	COG0789	DNA-binding transcriptional regulator, MerR family	124
649658365	320	32.49	23	261	41	314	1.0e-37	150	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
649658366	352	29.25	7	295	26	314	2.0e-34	139	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
649658368	262	32.4	4	256	26	311	7.0e-39	154	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
649658371	312	48	3	302	1	297	6.0e-91	327	COG1090	NAD dependent epimerase/dehydratase family enzyme	297
649658376	481	42.47	1	477	2	459	1.0e-125	443	COG0415	Deoxyribodipyrimidine photolyase	461
649658377	317	41.51	157	315	1	159	9.0e-42	164	COG3272	Uncharacterized conserved protein YbgA, DUF1722 family	163
649658382	256	27.03	6	255	4	262	1.0e-34	140	COG0300	Short-chain dehydrogenase	265
649658383	419	46.06	1	416	9	423	1.0e-128	453	COG2907	Predicted NAD/FAD-binding protein	447
649658384	261	36.65	1	248	5	248	1.0e-56	213	COG3496	Uncharacterized conserved protein, DUF1365 family	261
649658385	435	42.16	139	425	5	283	7.0e-84	304	COG2230	Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases	283
649658389	527	26.03	20	527	57	554	3.0e-63	236	COG2831	Hemolysin activation/secretion protein	554
649658390	191	36.02	1	185	1	177	4.0e-36	144	COG0461	Orotate phosphoribosyltransferase	201
649658392	141	40.59	41	141	10	110	4.0e-19	87.3	COG0607	Rhodanese-related sulfurtransferase	110
649658393	308	23.78	72	246	44	225	2.0e-04	40.3	COG3698	Uncharacterized protein YigE, DUF2233 family	250
649658394	545	25.14	51	386	4	335	2.0e-35	144	COG0642	Signal transduction histidine kinase	336
649658397	498	46.4	10	475	3	470	2.0e-90	327	COG1007	NADH:ubiquinone oxidoreductase subunit 2 (chain N)	475
649658398	551	34.17	6	522	6	493	8.0e-96	344	COG1008	NADH:ubiquinone oxidoreductase subunit 4 (chain M)	497
649658399	519	44.6	7	512	1	496	2.0e-116	413	COG1008	NADH:ubiquinone oxidoreductase subunit 4 (chain M)	497
649658400	667	45.81	11	586	3	568	1.0e-128	453	COG1009	NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit	606
649658401	100	49	1	100	1	100	5.0e-19	85.9	COG0713	NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K)	100
649658402	174	40	4	163	6	163	5.0e-14	71	COG0839	NADH:ubiquinone oxidoreductase subunit 6 (chain J)	166
649658403	202	28.29	15	166	4	149	3.0e-30	124	COG1143	Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)	172
649658404	902	30.8	16	901	6	939	0.0e+00	617	COG3383	Predicted molibdopterin-dependent oxidoreductase YjgC	978
649658405	415	53.92	21	415	4	398	0.0e+00	545	COG0649	NADH:ubiquinone oxidoreductase 49 kD subunit (chain D)	398
649658406	165	46.67	1	150	6	151	2.0e-33	135	COG0852	NADH:ubiquinone oxidoreductase 27 kD subunit (chain C)	176
649658407	175	65.75	16	160	20	164	4.0e-65	240	COG0377	NADH:ubiquinone oxidoreductase 20 kD subunit (chhain B) or related Fe-S oxidoreductase	194
649658408	127	55	8	127	2	121	3.0e-30	123	COG0838	NADH:ubiquinone oxidoreductase subunit 3 (chain A)	123
649658410	741	32.53	2	740	34	730	3.0e-114	406	COG1198	Primosomal protein N' (replication factor Y) - superfamily II helicase	730
649658413	532	25.5	159	502	20	358	1.0e-23	104	COG3852	Signal transduction histidine kinase, nitrogen specific	363
649658415	231	29.25	19	227	7	202	3.0e-25	108	COG0560	Phosphoserine phosphatase	212
649658416	212	31.31	2	207	4	212	1.0e-36	146	COG0602	Organic radical activating enzyme	212
649658417	506	48.45	22	503	15	483	0.0e+00	501	COG0260	Leucyl aminopeptidase	485
649658418	383	40.85	1	326	1	315	1.0e-78	287	COG1472	Periplasmic beta-glucosidase and related glycosidases	397
649658422	496	33.54	31	484	2	459	6.0e-47	182	COG0531	Amino acid transporter	466
649658423	258	41.46	1	246	2	243	2.0e-64	239	COG2071	Gamma-glutamyl-gamma-aminobutyrate hydrolase PuuD (putrescine degradation), contains GATase1-like domain	243
649658426	421	27.04	14	396	1	364	5.0e-36	145	COG0006	Xaa-Pro aminopeptidase	384
649658427	284	30.53	1	92	1	94	7.0e-10	58	COG1826	Sec-independent protein translocase protein TatA	94
649658432	418	69.53	14	418	1	406	0.0e+00	664	COG1219	ATP-dependent protease Clp, ATPase subunit	408
649658433	211	75	1	192	2	193	1.0e-85	309	COG0740	ATP-dependent protease ClpP, protease subunit	200
649658434	441	35.57	1	433	1	419	9.0e-76	277	COG0544	FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)	441
649658437	400	28.94	23	367	3	351	3.0e-43	169	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
649658438	501	29.08	287	478	56	244	5.0e-23	102	COG1360	Flagellar motor protein MotB	244
649658440	142	55.24	1	139	1	130	1.0e-38	152	COG1970	Large-conductance mechanosensitive channel	130
649658441	369	20.59	135	363	40	262	2.0e-10	60	COG3137	Putative salt-induced outer membrane protein YdiY	262
649658444	598	38.02	163	596	113	560	6.0e-99	355	COG3829	Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding Fis domains	560
649658446	576	20.1	380	571	10	188	2.0e-06	47.5	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
649658449	702	18.58	1	622	5	601	3.0e-19	90.5	COG2982	Uncharacterized protein involved in outer membrane biogenesis	648
649658451	625	39.7	1	533	1	483	3.0e-124	439	COG2812	DNA polymerase III, gamma/tau subunits	515
649658452	107	51.96	6	107	5	105	6.0e-21	92.6	COG0718	Conserved DNA-binding protein YbaB (function unknown)	105
649658453	200	53.37	8	200	6	198	3.0e-72	264	COG0353	Recombinational DNA repair protein RecR	198
649658454	138	42.31	33	135	13	116	5.0e-17	80.5	COG1734	RNA polymerase-binding transcription factor DksA	120
649658455	381	20.2	203	381	24	215	6.0e-06	45.8	COG5010	Flp pilus assembly protein TadD, contains TPR repeats	257
649658458	139	29.91	1	115	1	114	3.0e-16	77.6	COG1569	Predicted nucleic acid-binding protein, contains PIN domain	142
649658466	373	31.54	85	327	34	291	3.0e-32	132	COG4974	Site-specific recombinase XerD	300
649658468	438	59.63	1	434	2	437	0.0e+00	636	COG1206	Folate-dependent tRNA-U54 methylase TrmFO/GidA	439
649658469	317	43.23	1	301	5	300	4.0e-78	285	COG4974	Site-specific recombinase XerD	300
649658470	178	63.43	2	176	1	175	4.0e-67	247	COG5405	ATP-dependent protease HslVU (ClpYQ), peptidase subunit	178
649658471	467	61.98	13	467	2	444	0.0e+00	621	COG1220	ATP-dependent protease HslVU (ClpYQ), ATPase subunit	444
649658472	298	50.72	22	297	1	264	4.0e-81	294	COG0548	Acetylglutamate kinase	265
649658474	179	53.85	1	169	3	170	2.0e-57	214	COG0663	Carbonic anhydrase or acetyltransferase, isoleucine patch superfamily	176
649658475	484	38.03	14	458	1	436	8.0e-120	424	COG0621	tRNA A37 methylthiotransferase MiaB	437
649658476	492	44.25	38	383	17	341	2.0e-70	260	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
649658477	467	36.76	130	467	4	334	9.0e-49	188	COG0642	Signal transduction histidine kinase	336
649658478	223	47.16	1	223	1	228	7.0e-62	230	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
649658480	336	25.42	3	333	16	362	2.0e-34	140	COG4269	Uncharacterized membrane protein YjgN, DUF898 family	364
649658483	551	55.79	1	546	4	562	0.0e+00	600	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
649658484	961	58.68	459	933	2	496	0.0e+00	722	COG1003	Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain	496
649658486	328	40.06	5	326	1	307	3.0e-77	282	COG1957	Inosine-uridine nucleoside N-ribohydrolase	311
649658487	308	39.68	1	298	1	310	5.0e-53	201	COG0524	Sugar or nucleoside kinase, ribokinase family	311
649658489	181	21.95	6	169	1	160	1.0e-17	83.1	COG3663	G:T/U-mismatch repair DNA glycosylase	169
649658491	172	26.96	32	143	7	119	1.0e-07	49.6	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
649658492	369	45.38	1	363	5	371	2.0e-107	383	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
649658494	408	42.31	9	397	5	387	3.0e-88	319	COG4398	Small ligand-binding sensory domain FIST	389
649658496	421	43.66	53	398	9	334	5.0e-67	248	COG3191	L-aminopeptidase/D-esterase	348
649658497	465	36.7	1	465	1	427	6.0e-79	288	COG1236	RNA processing exonuclease, beta-lactamase fold, Cft2 family	427
649658498	288	41.28	113	280	31	194	7.0e-39	154	COG1611	Predicted Rossmann fold nucleotide-binding protein	205
649658501	172	21.23	2	147	7	148	1.0e-07	49.6	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
649658502	208	35.1	6	207	5	212	3.0e-33	134	COG2928	Uncharacterized membrane protein	222
649658503	132	26.83	49	130	1	55	2.0e-04	38.7	COG2835	Uncharacterized conserved protein YbaR, Trm112 family	60
649658508	346	27.27	68	326	29	298	2.0e-22	99.9	COG4974	Site-specific recombinase XerD	300
649658516	380	26.69	27	358	8	344	4.0e-33	136	COG1721	Uncharacterized conserved protein, DUF58 family, contains vWF domain	416
649658517	334	42.06	25	334	12	329	2.0e-69	256	COG0714	MoxR-like ATPase	329
649658519	338	30.08	44	299	29	263	3.0e-26	112	COG3016	Uncharacterized iron-regulated protein	295
649658522	267	33.17	74	253	9	213	6.0e-23	101	COG2755	Lysophospholipase L1 or related esterase	216
649658523	234	48.89	1	222	1	225	2.0e-74	272	COG1136	ABC-type lipoprotein export system, ATPase component	226
649658524	890	34.2	3	888	5	827	0.0e+00	507	COG3127	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component	829
649658525	838	27.24	10	827	40	858	5.0e-115	409	COG0308	Aminopeptidase N	859
649658526	238	53.28	10	236	1	227	7.0e-70	257	COG0120	Ribose 5-phosphate isomerase	227
649658527	361	33.99	2	354	8	319	5.0e-71	261	COG0837	Glucokinase	320
649658528	253	39.36	6	249	2	238	2.0e-52	199	COG0363	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase	238
649658529	567	28.72	46	395	41	433	1.0e-38	154	COG0166	Glucose-6-phosphate isomerase	446
649658532	122	29.41	12	111	7	107	1.0e-08	52.2	COG0594	RNase P protein component	117
649658533	580	39.34	260	549	5	300	2.0e-62	233	COG0706	Membrane protein insertase Oxa1/YidC/SpoIIIJ, required for the localization of integral membrane proteins	314
649658534	476	46.62	4	476	2	454	0.0e+00	465	COG0486	tRNA U34 5-carboxymethylaminomethyl modifying GTPase MnmE/TrmE	454
649658535	624	58.45	1	620	1	619	0.0e+00	928	COG0445	tRNA U34 5-carboxymethylaminomethyl modifying enzyme MnmG/GidA	621
649658536	218	29.03	8	216	1	213	6.0e-32	130	COG0357	16S rRNA G527 N7-methylase RsmG (former glucose-inhibited division protein B)	215
649658537	258	44.36	1	255	1	256	1.0e-60	226	COG1192	Cellulose biosynthesis protein BcsQ	259
649658538	283	36.8	28	276	4	240	2.0e-33	136	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
649658539	162	31.36	29	146	13	130	1.0e-16	79.6	COG1664	Cytoskeletal protein CcmA, bactofilin family	146
649658541	360	41.69	1	360	1	355	8.0e-99	354	COG0482	tRNA U34 2-thiouridine synthase MnmA/TrmU, contains the PP-loop ATPase domain	356
649658542	179	32.58	1	177	2	178	2.0e-29	122	COG0712	FoF1-type ATP synthase, delta subunit	178
649658543	505	71.29	1	498	1	498	0.0e+00	818	COG0056	FoF1-type ATP synthase, alpha subunit	504
649658544	295	48.97	5	295	1	287	5.0e-87	314	COG0224	FoF1-type ATP synthase, gamma subunit	287
649658545	480	76.56	1	479	1	468	0.0e+00	822	COG0055	FoF1-type ATP synthase, beta subunit	468
649658546	140	37.88	5	134	4	135	9.0e-25	106	COG0355	FoF1-type ATP synthase, epsilon subunit	135
649658549	320	44.22	2	293	1	289	8.0e-75	274	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
649658551	321	47.67	9	306	2	289	1.0e-79	289	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
649658555	273	42.86	1	266	5	270	1.0e-44	173	COG1108	ABC-type Mn2+/Zn2+ transport system, permease component	274
649658556	259	43.75	4	259	3	250	2.0e-72	265	COG1121	ABC-type Mn2+/Zn2+ transport system, ATPase component	254
649658557	308	31.51	1	307	5	303	2.0e-56	212	COG0803	ABC-type Zn uptake system ZnuABC, Zn-binding component ZnuA	303
649658558	394	43.46	1	380	5	369	2.0e-79	289	COG2377	1,6-Anhydro-N-acetylmuramate kinase	371
649658567	316	53.44	1	305	2	306	6.0e-110	390	COG0223	Methionyl-tRNA formyltransferase	307
649658568	449	42.47	85	447	1	353	2.0e-79	290	COG0144	16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family	355
649658569	234	60.91	4	223	2	220	1.0e-84	305	COG0036	Pentose-5-phosphate-3-epimerase	220
649658570	514	31.47	139	508	3	334	6.0e-85	308	COG0016	Phenylalanyl-tRNA synthetase alpha subunit	335
649658571	572	27.13	1	570	1	548	1.0e-78	287	COG0072	Phenylalanyl-tRNA synthetase beta subunit	650
649658572	122	60.17	1	118	1	118	1.0e-33	134	COG0292	Ribosomal protein L20	118
649658573	65	49.18	4	64	3	63	8.0e-08	48.7	COG0291	Ribosomal protein L35	65
649658574	168	52.12	4	168	9	173	4.0e-55	207	COG0290	Translation initiation factor IF-3	176
649658575	651	54.17	38	637	1	580	0.0e+00	760	COG0441	Threonyl-tRNA synthetase	589
649658577	90	53.33	1	90	2	91	1.0e-20	91.4	COG0776	Bacterial nucleoid DNA-binding protein	94
649658578	196	31.25	104	183	13	92	1.0e-09	56.5	COG2901	DNA-binding protein Fis (factor for inversion stimulation)	98
649658579	150	32.17	1	143	1	140	4.0e-25	107	COG1959	DNA-binding transcriptional regulator, IscR family	150
649658580	847	31.33	25	572	4	501	4.0e-99	356	COG0155	Sulfite reductase, beta subunit (hemoprotein)	510
649658581	240	37.7	4	240	3	242	4.0e-50	191	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
649658582	355	38.95	1	343	4	338	1.0e-68	253	COG0547	Anthranilate phosphoribosyltransferase	338
649658583	265	33.94	3	265	18	261	2.0e-45	176	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
649658584	626	37.92	21	428	4	414	8.0e-113	401	COG2895	Sulfate adenylyltransferase subunit 1, EFTu-like GTPase family	431
649658585	306	35.43	16	266	32	263	7.0e-44	171	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
649658588	251	52.28	1	240	1	241	1.0e-81	295	COG0217	Transcriptional and/or translational regulatory protein YebC/TACO1	241
649658589	202	42.29	1	199	1	200	9.0e-48	183	COG0632	Holliday junction resolvasome RuvABC DNA-binding subunit	201
649658591	345	59.02	3	329	2	328	0.0e+00	475	COG2255	Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit	332
649658592	358	51.46	89	357	2	275	2.0e-93	335	COG0077	Prephenate dehydratase	279
649658593	361	44.69	7	356	4	351	6.0e-92	331	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
649658594	337	61.29	58	335	8	286	3.0e-107	381	COG2876	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase	286
649658595	298	42.31	4	288	1	277	2.0e-60	225	COG0287	Prephenate dehydrogenase	279
649658596	442	43.94	6	434	7	424	5.0e-118	418	COG0128	5-enolpyruvylshikimate-3-phosphate synthase	428
649658597	232	46.64	11	232	2	221	2.0e-61	228	COG0283	Cytidylate kinase	222
649658598	231	31.55	1	183	32	214	3.0e-20	91.9	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
649658599	571	50.76	22	543	13	526	0.0e+00	534	COG0539	Ribosomal protein S1	541
649658600	299	42.58	24	270	37	290	4.0e-55	208	COG0616	Periplasmic serine protease, ClpP class	317
649658601	92	43.48	1	92	2	92	3.0e-23	99.8	COG0776	Bacterial nucleoid DNA-binding protein	94
649658609	315	36.33	1	298	1	297	1.0e-40	160	COG0583	DNA-binding transcriptional regulator, LysR family	297
649658610	159	25.44	41	150	6	118	7.0e-11	60.3	COG2346	Truncated hemoglobin YjbI	133
649658613	419	53.06	10	418	4	411	0.0e+00	511	COG0334	Glutamate dehydrogenase/leucine dehydrogenase	411
649658614	275	40.81	18	240	1	214	3.0e-61	228	COG0321	Lipoate-protein ligase B	221
649658615	358	34.67	20	356	1	344	4.0e-44	172	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
649658616	419	42.23	69	407	14	328	1.0e-68	254	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
649658617	292	42.75	4	263	2	255	5.0e-66	244	COG2519	tRNA A58 N-methylase Trm61	256
649658618	253	45.45	3	249	2	251	2.0e-50	192	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
649658619	284	47.57	2	284	1	282	8.0e-76	277	COG0169	Shikimate 5-dehydrogenase	283
649658620	176	40.36	5	170	3	166	4.0e-41	160	COG0703	Shikimate kinase	172
649658622	86	32.39	1	70	1	71	3.0e-10	56.8	COG3077	Antitoxin component of the RelBE or YafQ-DinJ toxin-antitoxin module	88
649658623	89	47.25	1	88	1	91	1.0e-17	81.5	COG3041	mRNA-degrading endonuclease (mRNA interferase) YafQ, toxin component of the YafQ-DinJ toxin-antitoxin module	91
649658629	84	38.46	5	68	7	71	4.0e-10	56.4	COG3077	Antitoxin component of the RelBE or YafQ-DinJ toxin-antitoxin module	88
649658630	89	47.25	1	88	1	91	2.0e-20	91.1	COG3041	mRNA-degrading endonuclease (mRNA interferase) YafQ, toxin component of the YafQ-DinJ toxin-antitoxin module	91
649658634	463	27.43	95	436	83	405	7.0e-23	102	COG4949	Uncharacterized membrane-anchored protein	424
649658640	509	52.43	10	503	2	480	0.0e+00	645	COG0364	Glucose-6-phosphate 1-dehydrogenase	483
649658641	181	52	1	173	1	174	1.0e-64	238	COG0225	Peptide methionine sulfoxide reductase MsrA	174
649658643	287	31.32	20	281	1	258	4.0e-46	178	COG0037	tRNA(Ile)-lysidine synthase TilS/MesJ	298
649658644	155	24.65	1	141	2	131	7.0e-16	76.8	COG0394	Protein-tyrosine-phosphatase	139
649658646	340	26.37	30	328	20	313	9.0e-34	137	COG1181	D-alanine-D-alanine ligase and related ATP-grasp enzymes	317
649658650	201	55.7	1	201	1	228	3.0e-79	287	COG0588	Phosphoglycerate mutase (BPG-dependent)	230
649658655	402	56.31	3	395	6	398	0.0e+00	538	COG4992	Acetylornithine/succinyldiaminopimelate/putrescine aminotransferase	404
649658656	326	56.86	15	319	6	310	2.0e-121	428	COG0078	Ornithine carbamoyltransferase	310
649658657	405	59.8	7	402	5	401	0.0e+00	594	COG0137	Argininosuccinate synthase	403
649658658	484	55.02	27	484	2	459	0.0e+00	586	COG0165	Argininosuccinate lyase	459
649658660	420	49.87	1	392	1	394	2.0e-117	416	COG0019	Diaminopimelate decarboxylase	394
649658661	290	51.19	1	290	4	296	1.0e-91	329	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
649658662	267	53.76	1	266	2	266	1.0e-88	319	COG0289	Dihydrodipicolinate reductase	266
649658663	86	39.02	44	83	2	42	1.0e-06	45	COG3350	Uncharacterized conserved protein, YHS domain	53
649658665	215	47.6	1	215	8	236	3.0e-65	241	COG0176	Transaldolase	239
649658666	232	27.16	1	226	7	200	3.0e-26	112	COG1573	Uracil-DNA glycosylase	202
649658668	446	46.47	8	445	3	421	8.0e-114	404	COG2379	Glycerate-2-kinase	422
649658670	471	29.76	38	445	15	417	3.0e-58	219	COG1322	DNA anti-recombination protein (rearrangement mutator) RmuC	448
649658671	142	28.67	8	115	16	158	2.0e-10	58.6	COG4696	Predicted phosphohydrolase, Cof family, HAD superfamily	180
649658673	285	52.67	1	278	1	281	3.0e-96	345	COG0414	Panthothenate synthetase	285
649658674	187	45.06	1	162	1	158	3.0e-40	158	COG0801	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase	160
649658675	391	42.08	13	389	5	388	5.0e-109	388	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
649658676	431	22.52	67	418	5	363	3.0e-12	66.7	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
649658677	119	50	5	112	26	133	7.0e-33	132	COG4446	Uncharacterized conserved protein, DUF1499 family	141
649658679	285	34.88	28	285	8	263	5.0e-42	164	COG1682	ABC-type polysaccharide/polyol phosphate export permease	263
649658680	433	48.39	3	250	1	238	5.0e-80	292	COG1134	ABC-type polysaccharide/polyol phosphate transport system, ATPase component	249
649658687	202	40.43	1	184	2	189	1.0e-33	136	COG0406	Broad specificity phosphatase PhoE	208
649658688	343	20.07	23	284	42	293	4.0e-10	59.3	COG4447	Uncharacterized protein related to plant photosystem II stability/assembly factor	339
649658689	378	38.4	22	370	31	354	2.0e-69	256	COG5621	Predicted secreted hydrolase	354
649658690	229	35.24	18	221	3	210	2.0e-27	116	COG2802	Uncharacterized protein, similar to the N-terminal domain of Lon protease	221
649658691	323	44.48	6	311	4	293	2.0e-74	273	COG1131	ABC-type multidrug transport system, ATPase component	293
649658694	252	25.42	1	251	1	290	4.0e-33	135	COG1234	Ribonuclease BN, tRNA processing enzyme	292
649658695	152	33.62	27	142	9	124	8.0e-13	66.5	COG1846	DNA-binding transcriptional regulator, MarR family	126
649658697	277	28.74	46	273	35	279	8.0e-31	127	COG1408	Predicted phosphohydrolase, MPP superfamily	284
649658699	350	33.67	1	347	2	397	3.0e-69	256	COG0585	tRNA(Glu) U13 pseudouridine synthase TruD	406
649658700	414	48.02	8	410	6	403	4.0e-120	425	COG1915	Uncharacterized conserved protein, contains Saccharopine dehydrogenase N-terminal (SDHN) domain	415
649658701	266	34.83	3	265	4	267	3.0e-55	208	COG1834	N-Dimethylarginine dimethylaminohydrolase	267
649658703	341	52.57	7	337	2	329	2.0e-112	399	COG0240	Glycerol-3-phosphate dehydrogenase	329
649658704	250	54.25	4	245	1	247	3.0e-71	261	COG1691	NCAIR mutase (PurE)-related protein	254
649658706	402	44.16	5	389	3	381	5.0e-99	354	COG1641	Uncharacterized conserved protein, DUF111 family	387
649658707	337	25.97	1	333	6	318	2.0e-24	106	COG0530	Ca2+/Na+ antiporter	320
649658708	347	48.33	10	338	2	328	4.0e-96	344	COG1995	4-hydroxy-L-threonine phosphate dehydrogenase PdxA	332
649658710	267	47.1	6	264	2	256	2.0e-70	259	COG0030	16S rRNA A1518 and A1519 N6-dimethyltransferase RsmA/KsgA/DIM1 (may also have DNA glycosylase/AP lyase activity)	259
649658711	790	30.53	14	779	106	852	6.0e-120	425	COG1674	DNA segregation ATPase FtsK/SpoIIIE and related proteins	858
649658712	240	26.61	1	233	4	209	5.0e-24	104	COG2834	Outer membrane lipoprotein-sorting protein	211
649658715	771	36.26	498	768	72	334	2.0e-41	164	COG0642	Signal transduction histidine kinase	336
649658716	325	29.94	28	323	11	319	1.0e-34	140	COG2984	ABC-type uncharacterized transport system, periplasmic component	322
649658718	666	21.75	1	618	7	651	1.0e-35	145	COG4771	Outer membrane receptor for ferrienterochelin and colicins	699
649658719	649	21.24	14	627	13	667	2.0e-42	167	COG4771	Outer membrane receptor for ferrienterochelin and colicins	699
649658723	770	40.29	372	770	15	420	2.0e-73	271	COG4995	Uncharacterized conserved protein, contains CHAT domain	420
649658724	586	25.7	15	580	10	551	1.0e-73	271	COG2831	Hemolysin activation/secretion protein	554
649658725	1030	21.75	95	892	39	842	2.0e-05	45.9	COG3210	Large exoprotein involved in heme utilization or adhesion	1013
649658727	462	23.08	18	462	8	438	5.0e-30	125	COG2067	Long-chain fatty acid transport protein	440
649658731	171	21.66	21	169	11	159	1.0e-03	36.8	COG5615	Uncharacterized membrane protein	161
649658732	467	37.29	37	385	7	345	2.0e-59	223	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
649658733	703	21.56	1	164	4	153	1.0e-07	52.3	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
649658734	551	23.28	124	452	94	436	2.0e-26	114	COG1032	Radical SAM superfamily enzyme YgiQ, UPF0313 family	490
649658735	258	42.92	27	258	8	237	4.0e-63	234	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
649658742	109	64.81	1	108	9	116	2.0e-34	137	COG3169	Uncharacterized conserved protein, DUF486 family	116
649658747	831	19.21	27	426	104	473	4.0e-08	53.8	COG0433	Archaeal DNA helicase HerA or a related bacterial ATPase, contains HAS-barrel and ATPase domains	520
649658749	212	39.61	7	212	4	210	2.0e-43	169	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
649658750	226	38.65	7	213	1	205	5.0e-42	164	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
649658753	185	45.51	19	185	3	168	4.0e-37	147	COG2862	Uncharacterized membrane protein YqhA	169
649658754	954	38.16	373	653	68	336	1.0e-44	175	COG0642	Signal transduction histidine kinase	336
649658755	1610	37.45	1035	1304	63	326	7.0e-46	180	COG0642	Signal transduction histidine kinase	336
649658756	218	38.83	10	215	2	205	2.0e-44	172	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
649658757	441	41.55	6	417	2	412	6.0e-99	354	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
649658759	265	50.88	183	239	4	60	1.0e-14	74.3	COG2771	DNA-binding transcriptional regulator, CsgD family	65
649658765	602	46.97	6	599	5	581	0.0e+00	564	COG0322	Excinuclease UvrABC, nuclease subunit	581
649658766	289	43.06	5	282	3	272	4.0e-68	251	COG0253	Diaminopimelate epimerase	272
649658767	132	21.43	4	124	1	138	4.0e-09	53.7	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
649658768	163	27.08	12	141	4	145	7.0e-09	53.7	COG1247	L-amino acid N-acyltransferase YncA	169
649658769	240	29.61	30	229	57	257	1.0e-22	100	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
649658770	389	34.93	6	212	5	204	6.0e-22	98.5	COG1994	Zn-dependent protease (includes SpoIVFB)	230
649658771	283	23.51	14	276	27	293	5.0e-20	91.9	COG1295	Uncharacterized membrane protein, BrkB/YihY/UPF0761 family (not an RNase)	303
649658772	491	43.94	4	490	1	474	2.0e-89	323	COG1007	NADH:ubiquinone oxidoreductase subunit 2 (chain N)	475
649658773	522	55.44	2	494	1	496	0.0e+00	536	COG1008	NADH:ubiquinone oxidoreductase subunit 4 (chain M)	497
649658774	632	46.51	3	628	1	606	0.0e+00	483	COG1009	NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit	606
649658775	101	57.58	2	100	1	99	3.0e-21	93.2	COG0713	NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K)	100
649658776	206	39.88	38	200	3	165	3.0e-23	101	COG0839	NADH:ubiquinone oxidoreductase subunit 6 (chain J)	166
649658777	191	34.42	17	170	5	151	2.0e-33	135	COG1143	Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)	172
649658778	355	51	7	355	11	332	1.0e-90	327	COG1005	NADH:ubiquinone oxidoreductase subunit 1 (chain H)	332
649658779	889	31.74	9	888	6	938	0.0e+00	647	COG3383	Predicted molibdopterin-dependent oxidoreductase YjgC	978
649658780	435	60.3	20	417	24	420	0.0e+00	601	COG1894	NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F)	424
649658781	178	47.13	1	157	4	160	1.0e-50	192	COG1905	NADH:ubiquinone oxidoreductase 24 kD subunit (chain E)	160
649658782	583	57.73	196	583	11	398	0.0e+00	560	COG0649	NADH:ubiquinone oxidoreductase 49 kD subunit (chain D)	398
649658783	159	67.32	4	155	13	164	5.0e-67	246	COG0377	NADH:ubiquinone oxidoreductase 20 kD subunit (chhain B) or related Fe-S oxidoreductase	194
649658784	123	55.65	9	123	7	121	2.0e-29	121	COG0838	NADH:ubiquinone oxidoreductase subunit 3 (chain A)	123
649658785	420	35.01	20	384	3	364	1.0e-73	270	COG1565	SAM-dependent methyltransferase, MidA family	370
649658788	321	43.87	4	311	19	313	9.0e-65	240	COG2826	Transposase and inactivated derivatives, IS30 family	318
649658792	901	56.28	2	893	1	820	0.0e+00	1046	COG0653	Preprotein translocase subunit SecA (ATPase, RNA helicase)	822
649658793	399	27.35	57	272	7	228	2.0e-12	66.9	COG3063	Tfp pilus assembly protein PilF	250
649658797	380	21.08	157	379	22	244	1.0e-08	54.4	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
649658798	193	23.87	41	182	1	153	6.0e-16	77.6	COG1225	Peroxiredoxin	157
649658802	177	28.46	35	151	2	130	1.0e-12	66.4	COG1225	Peroxiredoxin	157
649658804	774	16.36	67	770	22	765	1.0e-27	118	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
649658806	469	18.24	40	453	13	402	9.0e-07	48.8	COG1228	Imidazolonepropionase or related amidohydrolase	406
649658807	752	18.15	4	752	2	768	1.0e-35	145	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
649658808	657	25.16	30	657	5	618	9.0e-64	238	COG1506	Dipeptidyl aminopeptidase/acylaminoacyl peptidase	620
649658810	744	24.61	28	744	27	719	2.0e-43	171	COG4773	Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid	719
649658811	352	26.94	1	295	2	292	1.0e-13	71	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
649658813	785	28.89	49	772	7	757	2.0e-66	247	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
649658814	434	25.73	13	431	3	412	6.0e-37	148	COG3182	Uncharacterized iron-regulated membrane protein	442
649658816	124	39.02	1	119	9	130	3.0e-20	90.7	COG0848	Biopolymer transport protein ExbD	137
649658817	780	17.75	133	776	84	765	2.0e-26	114	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
649658819	738	16.78	7	738	12	768	4.0e-42	167	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
649658820	135	34.88	1	127	1	127	3.0e-15	74.1	COG1487	Predicted nucleic acid-binding protein, contains PIN domain	133
649658827	713	25.91	49	713	63	719	1.0e-71	264	COG4773	Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid	719
649658828	410	26.53	25	395	19	391	2.0e-48	187	COG1373	Predicted ATPase, AAA+ superfamily	398
649658830	411	27.53	32	400	6	385	8.0e-36	145	COG3182	Uncharacterized iron-regulated membrane protein	442
649658831	422	29.1	42	417	11	367	9.0e-22	98.3	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
649658832	232	50.23	10	229	1	221	9.0e-75	273	COG1136	ABC-type lipoprotein export system, ATPase component	226
649658834	389	23.08	1	384	4	405	6.0e-25	108	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
649658843	183	23.63	2	183	4	172	6.0e-19	87.3	COG3065	Starvation-inducible outer membrane lipoprotein	191
649658845	960	47.72	257	956	46	708	0.0e+00	726	COG2217	Cation transport ATPase	713
649658847	477	42	20	364	1	340	6.0e-65	242	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
649658851	209	25.19	8	130	5	135	3.0e-08	52	COG2165	Type II secretory pathway, pseudopilin PulG	149
649658853	357	40.75	1	341	7	350	3.0e-72	266	COG3437	Response regulator c-di-GMP phosphodiesterase, RpfG family, contains REC and HD-GYP domains	360
649658854	139	44.85	1	134	1	136	1.0e-33	135	COG0864	Metal-responsive transcriptional regulator, contains CopG/Arc/MetJ DNA-binding domain	136
649658856	681	16.03	10	681	36	768	2.0e-19	91.5	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
649658857	185	48.09	5	172	6	183	9.0e-46	176	COG2094	3-methyladenine DNA glycosylase Mpg	200
649658861	152	44.55	21	129	3	112	6.0e-14	70.2	COG1950	Uncharacterized membrane protein YvlD, DUF360 family	120
649658863	205	15.48	26	171	2	146	1.0e-03	36.9	COG2010	Cytochrome c, mono- and diheme variants	150
649658864	270	23.62	16	267	58	281	4.0e-08	52.3	COG2324	Uncharacterized membrane protein	281
649658865	327	29.53	1	327	1	314	1.0e-38	154	COG0451	Nucleoside-diphosphate-sugar epimerase	314
649658866	326	34.63	31	326	1	322	3.0e-67	248	COG0142	Geranylgeranyl pyrophosphate synthase	322
649658868	387	21.6	107	382	66	332	2.0e-06	47.3	COG4447	Uncharacterized protein related to plant photosystem II stability/assembly factor	339
649658872	642	19.63	290	482	6	217	1.0e-07	52.4	COG0790	TPR repeat	292
649658876	95	31.18	1	92	2	93	9.0e-09	52	COG3668	Plasmid stabilization system protein ParE	98
649658885	297	40.86	36	286	51	302	1.0e-59	223	COG4714	Uncharacterized membrane-anchored protein	303
649658886	237	23.3	16	178	25	199	1.0e-06	46.9	COG1994	Zn-dependent protease (includes SpoIVFB)	230
649658887	235	33.18	6	228	10	219	2.0e-39	155	COG0543	NAD(P)H-flavin reductase	252
649658889	147	18.33	28	146	7	122	1.0e-04	39.1	COG1586	S-adenosylmethionine decarboxylase or arginine decarboxylase	136
649658891	1058	31.05	2	1035	1	1007	0.0e+00	715	COG0841	Multidrug efflux pump subunit AcrB	1009
649658892	412	31.83	31	405	11	370	1.0e-31	131	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
649658893	215	22.96	9	203	7	200	5.0e-10	58.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
649658897	165	30.97	4	155	7	161	2.0e-25	108	COG4032	Sulfopyruvate decarboxylase, TPP-binding subunit (coenzyme M biosynthesis)	172
649658899	366	35.83	1	358	4	360	1.0e-82	300	COG0075	Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism protein PucG	383
649658900	239	26.67	1	237	4	230	2.0e-32	132	COG1213	Choline kinase	239
649658901	483	18.46	282	476	1	180	6.0e-11	62.7	COG0558	Phosphatidylglycerophosphate synthase	192
649658903	387	28.18	81	366	2	286	2.0e-24	107	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
649658904	403	28.46	6	378	10	380	8.0e-43	168	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649658905	369	21.65	9	369	3	379	2.0e-14	73.9	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649658906	514	22.76	1	479	3	476	4.0e-23	102	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
649658907	304	19.54	5	263	2	294	2.0e-11	63.6	COG1216	Glycosyltransferase, GT2 family	305
649658910	360	23.55	61	350	1	279	3.0e-14	73.2	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
649658912	668	39.9	33	620	1	561	1.0e-130	460	COG1966	Carbon starvation protein CstA	575
649658913	181	50	18	181	2	164	5.0e-43	167	COG1666	Uncharacterized conserved protein YajQ, UPF0234 family	165
649658916	430	51.15	1	430	2	435	0.0e+00	526	COG0017	Aspartyl/asparaginyl-tRNA synthetase	435
649658917	309	50	10	305	7	314	5.0e-102	364	COG0275	16S rRNA C1402 N4-methylase RsmH	314
649658919	572	40.57	5	562	12	599	2.0e-127	449	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
649658920	502	42.8	27	498	10	475	9.0e-122	430	COG0769	UDP-N-acetylmuramyl tripeptide synthase	475
649658921	487	43.83	12	479	2	451	5.0e-113	401	COG0770	UDP-N-acetylmuramyl pentapeptide synthase	451
649658922	358	44.05	29	358	8	316	1.0e-58	220	COG0472	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase	319
649658923	462	43.07	4	462	6	448	1.0e-113	403	COG0771	UDP-N-acetylmuramoylalanine-D-glutamate ligase	448
649658924	402	45.98	26	382	14	372	3.0e-86	312	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
649658925	373	38.67	1	362	1	357	1.0e-79	290	COG0707	UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase	357
649658926	460	51.52	1	458	3	457	0.0e+00	554	COG0773	UDP-N-acetylmuramate-alanine ligase	459
649658927	310	44.41	28	309	3	288	7.0e-78	284	COG0812	UDP-N-acetylenolpyruvoylglucosamine reductase	291
649658928	332	41.82	13	320	1	317	3.0e-77	282	COG1181	D-alanine-D-alanine ligase and related ATP-grasp enzymes	317
649658929	289	22.05	42	289	26	258	1.0e-16	80.5	COG1589	Cell division septal protein FtsQ	269
649658930	414	46.76	6	414	3	418	2.0e-119	422	COG0849	Cell division ATPase FtsA	418
649658931	400	56.19	1	331	1	330	2.0e-100	359	COG0206	Cell division GTPase FtsZ	338
649658932	247	39.26	16	241	12	247	2.0e-48	185	COG1496	Copper oxidase (laccase) domain	249
649658933	235	47.81	7	233	2	226	1.0e-70	259	COG0325	Uncharacterized pyridoxal phosphate-containing protein, affects Ilv metabolism, UPF0001 family	228
649658934	268	54.51	3	268	1	265	1.0e-74	273	COG0345	Pyrroline-5-carboxylate reductase	266
649658935	98	30.21	1	96	1	96	9.0e-07	45.2	COG0762	Uncharacterized conserved protein YggT, Ycf19 family	96
649658936	170	24.86	2	169	5	179	1.0e-07	49.6	COG3599	Cell division septum initiation DivIVA, interacts with FtsZ, MinD and other proteins	212
649658937	375	31.48	1	353	35	369	3.0e-32	133	COG1680	CubicO group peptidase, beta-lactamase class C family	390
649658939	178	34.12	1	166	12	181	1.0e-15	76.6	COG0558	Phosphatidylglycerophosphate synthase	192
649658941	405	40.99	1	405	1	397	9.0e-106	377	COG1459	Type II secretory pathway, component PulF	397
649658943	459	50.55	1	454	4	456	0.0e+00	523	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
649658944	304	39.56	3	275	1	267	2.0e-62	233	COG1947	4-diphosphocytidyl-2C-methyl-D-erythritol kinase	289
649658945	313	63.06	1	312	1	313	1.0e-123	436	COG0462	Phosphoribosylpyrophosphate synthetase	314
649658946	255	37.89	5	98	4	93	3.0e-14	72.6	COG1825	Ribosomal protein L25 (general stress protein Ctc)	93
649658947	196	45.16	1	184	2	187	2.0e-53	201	COG0193	Peptidyl-tRNA hydrolase	190
649658950	213	18.13	34	213	12	199	4.0e-04	38.1	COG3637	Opacity protein and related surface antigens	199
649658953	117	45.16	4	96	3	95	4.0e-25	106	COG0360	Ribosomal protein S6	112
649658954	130	47.15	2	118	1	123	3.0e-29	120	COG0629	Single-stranded DNA-binding protein	167
649658956	201	22.37	46	197	47	176	6.0e-14	70.8	COG1399	Uncharacterized metal-binding protein YceD, DUF177 family	176
649658958	343	50.3	1	328	2	333	4.0e-108	384	COG0416	Fatty acid/phospholipid biosynthesis enzyme	338
649658959	325	56.44	1	325	1	322	4.0e-114	404	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
649658960	316	55.08	5	307	4	308	2.0e-88	319	COG0331	Malonyl CoA-acyl carrier protein transacylase	310
649658961	247	52.36	1	245	1	251	4.0e-50	191	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
649658962	77	72.37	1	76	3	78	5.0e-11	59.6	COG0236	Acyl carrier protein	80
649658963	416	62.2	7	413	3	410	0.0e+00	519	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
649658964	234	53.22	1	233	2	229	8.0e-63	233	COG0571	dsRNA-specific ribonuclease	235
649658965	217	56.2	48	181	1	130	3.0e-43	168	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
649658968	415	33.9	114	407	74	335	4.0e-44	172	COG0642	Signal transduction histidine kinase	336
649658970	382	26.26	28	375	33	375	8.0e-36	145	COG3287	Uncharacterized conserved protein, contains FIST_N domain	379
649658974	286	59.01	4	286	1	283	7.0e-111	393	COG0190	5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase	283
649658975	296	29.87	6	290	4	284	5.0e-44	171	COG0685	5,10-methylenetetrahydrofolate reductase	291
649658976	262	54.75	1	262	2	264	3.0e-98	351	COG0413	Ketopantoate hydroxymethyltransferase	268
649658978	272	17.57	27	260	32	253	6.0e-03	34.9	COG1409	3',5'-cyclic AMP phosphodiesterase CpdA	301
649658980	945	36.3	242	509	78	335	3.0e-43	171	COG0642	Signal transduction histidine kinase	336
649658984	142	33.33	14	140	7	134	2.0e-29	121	COG0780	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF, C-terminal domain, T-fold superfamily	149
649658986	299	28.91	41	287	8	254	9.0e-44	170	COG1013	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, beta subunit	294
649658987	237	32.41	4	216	3	192	5.0e-27	114	COG1014	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, gamma subunit	203
649658988	107	27.27	1	77	24	87	2.0e-06	44.6	COG1144	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit	91
649658990	448	25.82	53	414	1	359	1.0e-52	200	COG0674	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, alpha subunit	365
649658996	287	35.48	1	274	1	273	1.0e-61	230	COG0266	Formamidopyrimidine-DNA glycosylase	273
649658997	399	27	12	398	11	383	2.0e-41	163	COG0045	Succinyl-CoA synthetase, beta subunit	387
649658998	606	35.31	1	318	1	292	3.0e-56	213	COG0074	Succinyl-CoA synthetase, alpha subunit	293
649658999	748	31.37	20	745	25	853	0.0e+00	612	COG1048	Aconitase A	861
649659000	743	70.66	1	743	1	743	0.0e+00	1186	COG2838	Monomeric isocitrate dehydrogenase	744
649659002	533	37.71	85	494	8	407	5.0e-88	318	COG0029	Aspartate oxidase	518
649659003	392	55.22	1	391	1	387	0.0e+00	492	COG0045	Succinyl-CoA synthetase, beta subunit	387
649659004	290	64.95	1	290	1	291	4.0e-116	411	COG0074	Succinyl-CoA synthetase, alpha subunit	293
649659006	544	23.98	8	471	2	474	8.0e-42	165	COG1032	Radical SAM superfamily enzyme YgiQ, UPF0313 family	490
649659008	418	61	1	418	3	420	0.0e+00	624	COG0499	S-adenosylhomocysteine hydrolase	420
649659009	382	65.13	1	382	1	388	0.0e+00	622	COG0192	S-adenosylmethionine synthetase	388
649659010	478	25.76	37	464	1	449	2.0e-51	196	COG1333	Cytochrome c biogenesis protein ResB	478
649659011	304	29.32	50	304	20	280	3.0e-27	115	COG0755	ABC-type transport system involved in cytochrome c biogenesis, permease component	281
649659012	207	34.56	47	169	3	135	8.0e-20	90.7	COG1225	Peroxiredoxin	157
649659013	178	29.55	35	153	4	133	3.0e-17	81.8	COG1225	Peroxiredoxin	157
649659014	248	44.59	5	225	8	219	6.0e-31	127	COG0785	Cytochrome c biogenesis protein CcdA	220
649659015	402	31.67	8	358	2	349	2.0e-47	183	COG0644	Dehydrogenase (flavoprotein)	396
649659016	306	29.12	54	235	68	249	5.0e-26	111	COG4105	Outer membrane protein assembly factor BamD, BamD/ComL family	254
649659017	330	46.67	1	330	1	322	3.0e-92	331	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
649659018	205	33.33	6	203	10	216	2.0e-28	118	COG1392	Uncharacterized conserved protein YkaA, distantly related to PhoU, UPF0111/DUF47 family	217
649659019	330	39.21	7	329	4	325	3.0e-56	212	COG0306	Phosphate/sulfate permease	326
649659020	619	32.13	166	603	18	447	3.0e-73	269	COG5002	Signal transduction histidine kinase	459
649659021	238	47.62	9	235	1	229	3.0e-62	231	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
649659022	320	62.76	1	289	2	291	1.0e-112	399	COG0761	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH	294
649659023	1227	30.36	1	1221	1	1156	0.0e+00	553	COG1196	Chromosome segregation ATPase	1163
649659024	724	33.7	153	696	1	510	1.0e-77	284	COG1657	Squalene cyclase	517
649659025	267	23.74	16	218	1	219	6.0e-13	68.1	COG0775	Nucleoside phosphorylase	234
649659026	255	45.82	4	254	12	262	2.0e-61	228	COG0767	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, permease component MlaE	267
649659027	253	45.38	1	237	8	245	9.0e-74	270	COG1127	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, ATPase component MlaF	263
649659029	204	24.88	7	198	2	202	6.0e-25	107	COG2854	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic MlaC component	202
649659032	648	55.73	1	624	2	625	0.0e+00	847	COG1154	Deoxyxylulose-5-phosphate synthase	627
649659033	401	60.78	3	357	1	357	0.0e+00	478	COG0821	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase IspG/GcpE	361
649659036	578	40.05	15	373	15	380	1.0e-55	211	COG4651	Predicted Kef-type K+ transport protein, K+/H+ antiporter domain	408
649659039	208	16.35	4	206	2	199	1.0e-03	36.9	COG3637	Opacity protein and related surface antigens	199
649659041	474	23.85	30	453	10	438	1.0e-22	101	COG0728	Peptidoglycan biosynthesis protein MviN/MurJ, putative lipid II flippase	518
649659043	339	24.36	71	338	75	380	3.0e-16	79.7	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649659044	594	33.33	1	587	2	554	6.0e-97	348	COG2192	Predicted carbamoyl transferase, NodU family	555
649659046	348	22.29	2	319	49	374	2.0e-21	97.3	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
649659048	386	45.95	1	383	1	373	7.0e-119	420	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
649659049	200	44.44	1	196	39	221	4.0e-49	187	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
649659050	656	39.6	17	618	1	585	0.0e+00	531	COG1086	NDP-sugar epimerase, includes UDP-GlcNAc-inverting 4,6-dehydratase FlaA1 and capsular polysaccharide biosynthesis protein EpsC	588
649659052	877	24.61	256	446	29	219	7.0e-20	93.3	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
649659053	408	20.55	120	396	84	359	1.0e-15	77.7	COG3524	Capsule polysaccharide export protein KpsE/RkpR	372
649659054	338	23.93	21	325	12	336	4.0e-23	102	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
649659060	312	22.73	109	305	4	175	2.0e-16	79.8	COG0723	Rieske Fe-S protein	177
649659061	371	35.51	16	365	5	348	2.0e-60	226	COG1290	Cytochrome b subunit of the bc complex	381
649659068	281	40.79	1	277	13	289	3.0e-41	162	COG0382	4-hydroxybenzoate polyprenyltransferase	289
649659087	883	21.09	216	483	1	306	3.0e-09	57.9	COG0515	Serine/threonine protein kinase	384
649659089	292	33.56	3	283	6	282	4.0e-41	162	COG2175	Taurine dioxygenase, alpha-ketoglutarate-dependent	286
649659097	216	43.6	4	214	1	210	3.0e-51	194	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
649659107	373	27.1	103	312	35	230	1.0e-19	90.8	COG2890	Methylase of polypeptide chain release factors	280
649659108	901	43.6	485	818	109	452	6.0e-88	319	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
649659111	149	26.95	1	136	1	135	6.0e-15	73.5	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
649659114	133	34.09	1	132	8	137	2.0e-30	124	COG0432	Thiamin phosphate synthase YjbQ, UPF0047 family	137
649659115	372	41.49	42	370	19	340	2.0e-57	216	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
649659119	257	27.23	22	251	19	231	3.0e-18	85.7	COG0638	20S proteasome, alpha and beta subunits	236
649659120	279	19.46	19	189	23	192	6.0e-07	48.4	COG0638	20S proteasome, alpha and beta subunits	236
649659124	910	21.79	379	603	36	288	2.0e-12	68.5	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
649659126	344	30.55	7	339	4	338	7.0e-59	221	COG0429	Predicted hydrolase of the alpha/beta-hydrolase fold	345
649659127	212	25.25	5	206	12	198	2.0e-18	86.2	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
649659131	235	27.52	3	218	1	195	2.0e-24	105	COG1014	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, gamma subunit	203
649659132	300	27.27	49	289	15	258	2.0e-42	166	COG1013	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, beta subunit	294
649659133	403	27.86	36	388	7	359	8.0e-58	217	COG0674	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, alpha subunit	365
649659136	137	32.56	11	134	2	115	4.0e-15	73.9	COG4911	Uncharacterized protein	123
649659137	423	71.36	7	423	2	420	0.0e+00	689	COG1158	Transcription termination factor Rho	422
649659138	68	54.17	1	68	1	72	6.0e-19	85.7	COG0254	Ribosomal protein L31	75
649659139	386	58.4	27	385	1	362	0.0e+00	488	COG0216	Protein chain release factor A	363
649659140	309	41.32	15	302	2	280	1.0e-61	230	COG2890	Methylase of polypeptide chain release factors	280
649659141	418	65.8	1	418	1	421	0.0e+00	606	COG0766	UDP-N-acetylglucosamine enolpyruvyl transferase	421
649659142	233	48.39	16	225	3	217	3.0e-57	215	COG0040	ATP phosphoribosyltransferase	290
649659143	427	50.13	31	426	27	421	0.0e+00	511	COG0141	Histidinol dehydrogenase	425
649659144	201	57.65	6	201	2	195	1.0e-72	266	COG0131	Imidazoleglycerol phosphate dehydratase HisB	195
649659145	202	57.71	1	201	3	202	5.0e-80	290	COG0118	Imidazoleglycerol phosphate synthase glutamine amidotransferase subunit HisH	204
649659147	241	50	1	238	2	238	1.0e-70	259	COG0106	Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase	241
649659148	256	66.02	1	254	1	256	1.0e-115	409	COG0107	Imidazole glycerol phosphate synthase subunit HisF	256
649659149	220	53.61	1	96	11	107	7.0e-39	153	COG0139	Phosphoribosyl-AMP cyclohydrolase	111
649659150	114	43.48	2	114	1	112	2.0e-28	117	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
649659151	614	34.18	6	551	2	527	2.0e-103	369	COG0358	DNA primase (bacterial type)	568
649659152	601	56.62	311	599	41	342	2.0e-86	313	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
649659154	258	26.07	1	234	2	235	2.0e-20	93.4	COG1579	Predicted  nucleic acid-binding protein, contains Zn-ribbon domain	239
649659155	219	43.44	2	217	75	295	2.0e-54	205	COG1039	Ribonuclease HIII	297
649659160	592	55.06	2	563	1	550	0.0e+00	682	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
649659161	172	58.6	1	157	3	159	4.0e-47	180	COG0440	Acetolactate synthase, small subunit	163
649659162	337	68.36	1	334	3	337	0.0e+00	549	COG0059	Ketol-acid reductoisomerase	338
649659163	216	40.74	9	216	27	238	8.0e-43	167	COG0688	Phosphatidylserine decarboxylase	239
649659164	261	36.96	10	237	3	227	1.0e-37	150	COG1183	Phosphatidylserine synthase	234
649659165	515	53.25	3	413	1	409	5.0e-126	444	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
649659167	358	54.42	1	356	2	345	1.0e-120	426	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
649659168	404	20.74	147	402	67	307	1.0e-04	41.1	COG3386	Sugar lactone lactonase YvrE	307
649659169	339	49.85	8	338	2	334	1.0e-99	356	COG0136	Aspartate-semialdehyde dehydrogenase	334
649659172	346	48.98	1	338	1	342	2.0e-116	412	COG0809	S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase)	348
649659175	349	65.38	7	339	1	338	1.0e-122	433	COG1077	Actin-like ATPase involved in cell morphogenesis	342
649659176	293	30.15	1	269	1	268	6.0e-36	144	COG1792	Cell shape-determining protein MreC	284
649659178	623	36.35	16	601	15	592	0.0e+00	471	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
649659179	372	43.37	14	367	14	372	6.0e-73	267	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
649659180	503	43.34	4	503	3	483	1.0e-115	410	COG1530	Ribonuclease G or E	487
649659181	378	40.11	1	374	1	350	7.0e-85	308	COG0758	Predicted Rossmann fold nucleotide-binding protein DprA/Smf involved in DNA uptake	350
649659182	779	48.33	3	591	1	555	0.0e+00	609	COG0550	DNA topoisomerase IA	570
649659183	158	44.59	1	157	1	157	5.0e-42	163	COG2193	Bacterioferritin (cytochrome b1)	157
649659184	159	42.68	1	157	1	157	2.0e-35	141	COG2193	Bacterioferritin (cytochrome b1)	157
649659185	179	34.65	49	175	1	127	5.0e-18	84.1	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
649659191	377	36.44	36	374	3	337	6.0e-70	257	COG1477	Thiamine biosynthesis lipoprotein ApbE	337
649659193	320	23.08	122	314	47	239	6.0e-10	58.6	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
649659194	124	38.21	1	119	9	130	1.0e-18	84.9	COG0848	Biopolymer transport protein ExbD	137
649659196	369	41.53	9	351	4	352	2.0e-96	346	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
649659197	534	35.77	15	520	14	528	1.0e-76	280	COG1178	ABC-type Fe3+ transport system, permease component	540
649659198	343	27.36	48	342	1	298	1.0e-37	151	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
649659199	153	39.86	16	152	3	140	2.0e-30	125	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
649659202	234	37.85	21	234	2	209	2.0e-41	162	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
649659203	507	48.7	6	503	5	497	0.0e+00	558	COG2317	Zn-dependent carboxypeptidase, M32 family	497
649659204	234	35.35	19	229	4	216	1.0e-38	153	COG4122	Predicted O-methyltransferase YrrM	219
649659205	303	22.42	25	302	26	290	3.0e-05	43	COG5006	Threonine/homoserine efflux transporter RhtA	292
649659206	368	31.28	1	357	1	342	3.0e-50	192	COG0673	Predicted dehydrogenase	342
649659208	1340	33.82	605	946	10	336	1.0e-46	183	COG0642	Signal transduction histidine kinase	336
649659209	464	44.54	1	453	5	457	1.0e-119	423	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
649659220	363	35.85	1	363	5	373	5.0e-67	248	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
649659223	266	48.85	7	266	6	262	4.0e-77	281	COG1635	Archaeal ribulose 1,5-bisphosphate synthetase/yeast thiazole synthase	262
649659224	638	66.03	143	608	1	432	0.0e+00	755	COG0422	Thiamine biosynthesis protein ThiC	432
649659225	625	22.93	38	347	26	298	6.0e-12	66.1	COG0501	Zn-dependent protease with chaperone function	302
649659229	150	21.05	1	144	10	158	3.0e-05	41.1	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
649659234	102	53.09	1	81	1	75	2.0e-18	84.3	COG3813	Uncharacterized protein	84
649659237	367	36.78	1	367	2	323	5.0e-90	324	COG0379	Quinolinate synthase	324
649659238	939	50.31	1	939	1	930	0.0e+00	1178	COG0060	Isoleucyl-tRNA synthetase	933
649659239	173	38.51	1	159	4	159	2.0e-29	121	COG0597	Lipoprotein signal peptidase	167
649659241	290	43.93	8	287	9	265	3.0e-58	218	COG1968	Undecaprenyl pyrophosphate phosphatase UppP	270
649659244	236	48.23	4	228	1	226	6.0e-82	297	COG1136	ABC-type lipoprotein export system, ATPase component	226
649659245	411	29.12	20	411	1	419	1.0e-33	137	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
649659246	412	22.83	34	366	4	344	1.0e-24	107	COG2206	HD-GYP domain, c-di-GMP phosphodiesterase class II (or its inactivated variant)	344
649659247	143	25	6	124	5	126	2.0e-04	38.4	COG4570	Holliday junction resolvase RusA (prophage-encoded endonuclease)	132
649659248	146	27.4	1	145	1	144	4.0e-21	93.7	COG2001	MraZ, DNA-binding transcriptional regulator and inhibitor of RsmH methyltransferase activity	146
649659250	270	38.91	10	247	1	224	1.0e-40	160	COG1040	Predicted amidophosphoribosyltransferases	225
649659251	232	49.09	8	226	1	220	2.0e-74	272	COG1136	ABC-type lipoprotein export system, ATPase component	226
649659252	308	37.38	2	307	1	309	2.0e-73	269	COG0167	Dihydroorotate dehydrogenase	310
649659255	344	43.17	13	324	10	322	3.0e-94	338	COG0502	Biotin synthase or related enzyme	335
649659256	466	24.06	72	447	15	389	6.0e-21	95.7	COG2956	Lipopolysaccharide biosynthesis regulator YciM, contains six TPR domains and a predicted metal-binding C-terminal domain	389
649659257	140	38.94	5	117	2	114	4.0e-30	123	COG0799	Ribosomal silencing factor RsfS, regulates association of 30S and 50S subunits	115
649659258	226	41.36	1	220	3	196	1.0e-52	200	COG1057	Nicotinic acid mononucleotide adenylyltransferase	197
649659259	373	49.32	6	373	3	369	8.0e-120	423	COG0263	Glutamate 5-kinase	369
649659260	343	60.3	4	336	3	337	0.0e+00	479	COG0536	GTPase involved in cell partioning and DNA repair	369
649659261	87	66.67	1	86	1	87	4.0e-28	116	COG0211	Ribosomal protein L27	87
649659262	104	49.5	1	101	1	101	1.0e-27	114	COG0261	Ribosomal protein L21	103
649659263	304	42.61	6	293	2	283	3.0e-69	255	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
649659264	117	46.15	1	78	1	78	3.0e-15	73.7	COG1314	Preprotein translocase subunit SecG	86
649659265	259	50.78	1	255	1	251	2.0e-80	291	COG0149	Triosephosphate isomerase	251
649659266	399	55.97	3	399	2	395	0.0e+00	502	COG0126	3-phosphoglycerate kinase	395
649659267	335	63.75	2	330	1	330	3.0e-129	455	COG0057	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase	335
649659268	810	34.71	12	809	5	753	2.0e-127	450	COG1193	dsDNA-specific endonuclease/ATPase MutS2	753
649659270	214	41.98	3	214	1	207	9.0e-43	166	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
649659275	537	29.55	268	537	8	314	2.0e-43	170	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
649659276	712	24.08	16	403	21	386	1.0e-32	135	COG4252	Extracellular (periplasmic) sensor domain CHASE2 (specificity unknown)	400
649659279	645	32.1	378	641	62	327	7.0e-32	132	COG0642	Signal transduction histidine kinase	336
649659280	461	46.44	1	461	2	461	0.0e+00	492	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
649659281	343	46.42	9	324	6	309	3.0e-82	298	COG1600	Epoxyqueuosine reductase  QueG (queuosine biosynthesis)	337
649659285	392	42.27	1	385	2	383	1.0e-96	346	COG0301	Adenylyl- and sulfurtransferase ThiI, participates in tRNA 4-thiouridine and thiamine biosynthesis	383
649659287	304	56.58	1	303	3	302	8.0e-95	340	COG0492	Thioredoxin reductase	305
649659288	200	42.37	1	177	2	174	2.0e-45	175	COG0237	Dephospho-CoA kinase	201
649659292	661	29.86	18	650	6	607	3.0e-93	336	COG3408	Glycogen debranching enzyme (alpha-1,6-glucosidase)	641
649659296	183	39.55	43	175	7	139	2.0e-20	92.3	COG3193	Uncharacterized conserved protein GlcG, DUF336 family	141
649659298	299	34.97	7	291	2	284	6.0e-48	184	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
649659301	373	27.27	13	359	3	354	3.0e-44	172	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
649659302	214	38.14	29	213	57	250	8.0e-43	167	COG2041	Periplasmic DMSO/TMAO reductase YedYZ, molybdopterin-dependent catalytic subunit	271
649659304	245	37.8	36	242	14	216	6.0e-23	101	COG0398	Uncharacterized membrane protein YdjX, TVP38/TMEM64 family, SNARE-associated domain	223
649659305	517	36.87	37	487	5	449	1.0e-109	390	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
649659309	891	27.61	482	877	16	402	5.0e-45	176	COG0617	tRNA nucleotidyltransferase/poly(A) polymerase	412
649659311	321	48.21	8	314	1	305	2.0e-89	322	COG1984	Allophanate hydrolase subunit 2	314
649659312	258	48.79	7	254	4	251	7.0e-75	274	COG1540	Lactam utilization protein B (function unknown)	252
649659313	234	51.85	11	226	1	216	5.0e-62	230	COG2049	Allophanate hydrolase subunit 1	223
649659314	426	23.2	63	419	51	394	8.0e-13	68.7	COG2814	Predicted arabinose efflux permease, MFS family	394
649659316	402	34.55	1	395	10	400	1.0e-60	227	COG1228	Imidazolonepropionase or related amidohydrolase	406
649659318	382	44.2	1	371	15	381	1.0e-113	403	COG0075	Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism protein PucG	383
649659319	497	28.1	291	495	13	222	1.0e-10	61.8	COG1266	Membrane protease YdiL, CAAX protease family	226
649659320	272	18.81	5	253	2	296	2.0e-10	59.6	COG0451	Nucleoside-diphosphate-sugar epimerase	314
649659322	214	43.75	5	210	2	208	6.0e-49	187	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
649659325	1459	36.64	1	897	3	808	0.0e+00	720	COG1201	Lhr-like helicase	814
649659330	759	46.99	314	757	11	455	3.0e-127	449	COG4402	Uncharacterized protein	457
649659333	139	25.84	4	92	2	90	1.0e-05	42.9	COG1669	Predicted nucleotidyltransferase	97
649659341	165	28.74	1	165	15	180	4.0e-12	64.3	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
649659343	1132	32.78	600	1127	5	529	2.0e-78	287	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
649659345	311	33.79	80	297	79	295	1.0e-42	167	COG2264	Ribosomal protein L11 methylase PrmA	300
649659347	219	21.28	30	206	34	220	7.0e-14	70.7	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
649659348	282	32.77	16	276	19	313	1.0e-40	160	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
649659353	264	53.23	1	262	2	263	7.0e-94	336	COG0351	Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase	263
649659356	348	24.17	42	333	44	334	2.0e-09	56.9	COG1413	HEAT repeat	335
649659358	222	35.78	1	218	1	218	1.0e-55	209	COG0819	Thiaminase	218
649659359	467	36.62	1	452	2	454	1.0e-114	407	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
649659360	228	39.87	59	213	3	157	6.0e-39	154	COG2077	Peroxiredoxin	158
649659361	294	30.5	21	293	1	280	3.0e-29	122	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
649659362	643	63.25	32	494	4	468	0.0e+00	663	COG5016	Pyruvate/oxaloacetate carboxyltransferase	472
649659365	274	23.32	19	269	35	314	1.0e-17	83.6	COG0226	ABC-type phosphate transport system, periplasmic component	318
649659371	338	31.62	64	334	28	289	2.0e-41	163	COG1398	Fatty-acid desaturase	289
649659372	341	52.31	1	341	6	351	4.0e-116	411	COG0407	Uroporphyrinogen-III decarboxylase	352
649659373	316	35.69	6	312	2	319	2.0e-75	276	COG0276	Protoheme ferro-lyase (ferrochelatase)	320
649659374	484	31.08	6	476	1	443	3.0e-81	296	COG1232	Protoporphyrinogen oxidase	444
649659379	765	28.45	78	764	38	707	2.0e-104	373	COG5000	Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation	712
649659380	466	49.25	1	464	3	460	0.0e+00	533	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
649659381	345	57.56	1	344	3	345	0.0e+00	463	COG0150	Phosphoribosylaminoimidazole (AIR) synthetase	345
649659382	216	57.84	1	204	1	200	6.0e-74	270	COG0299	Folate-dependent phosphoribosylglycinamide formyltransferase PurN	200
649659385	589	38.13	19	292	59	324	3.0e-42	166	COG0642	Signal transduction histidine kinase	336
649659388	149	54.36	1	148	1	148	1.0e-30	125	COG1610	Uncharacterized conserved protein YqeY	148
649659393	165	55.9	7	164	4	162	4.0e-58	217	COG0386	Glutathione peroxidase, house-cleaning role in reducing lipid peroxides	162
649659394	305	31.72	1	305	8	296	1.0e-39	157	COG0501	Zn-dependent protease with chaperone function	302
649659396	319	24.14	2	290	31	277	5.0e-18	85.4	COG1562	Phytoene/squalene synthetase	288
649659400	116	41.82	47	101	1	55	2.0e-13	67.6	COG3411	(2Fe-2S) ferredoxin	64
649659402	367	60.76	1	367	1	367	0.0e+00	487	COG0686	Alanine dehydrogenase	371
649659404	96	46.59	8	95	4	91	5.0e-18	82.6	COG1254	Acylphosphatase	92
649659405	332	41.94	23	329	31	339	1.0e-67	250	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
649659406	171	52.33	1	170	6	177	5.0e-43	167	COG0503	Adenine/guanine phosphoribosyltransferase or related PRPP-binding protein	179
649659407	191	36.67	64	183	2	116	7.0e-12	63.9	COG1734	RNA polymerase-binding transcription factor DksA	120
649659408	232	52	7	229	4	219	6.0e-70	257	COG0603	7-cyano-7-deazaguanine synthase (queuosine biosynthesis)	222
649659413	753	35.76	178	751	1	520	2.0e-116	413	COG1640	4-alpha-glucanotransferase	520
649659414	383	29.02	46	381	9	335	2.0e-36	146	COG0642	Signal transduction histidine kinase	336
649659415	464	50.87	1	456	2	457	0.0e+00	494	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
649659423	368	28.53	3	362	4	347	1.0e-52	200	COG3177	Fic family protein	348
649659431	356	26.12	62	327	7	291	2.0e-25	109	COG4974	Site-specific recombinase XerD	300
649659435	507	19.18	5	506	11	537	3.0e-15	77	COG3225	ABC-type uncharacterized transport system involved in gliding motility, auxiliary component	538
649659437	322	38.51	1	306	4	293	5.0e-73	267	COG1131	ABC-type multidrug transport system, ATPase component	293
649659445	443	32.4	112	429	29	330	3.0e-16	80	COG1413	HEAT repeat	335
649659446	719	33.99	20	711	5	704	0.0e+00	635	COG0058	Glucan phosphorylase	750
649659448	717	38.79	70	688	1	636	2.0e-122	433	COG0210	Superfamily I DNA or RNA helicase	655
649659453	401	74.06	1	401	1	394	0.0e+00	660	COG0050	Translation elongation factor EF-Tu, a GTPase	394
649659454	49	61.22	1	49	2	50	5.0e-09	52.5	COG0267	Ribosomal protein L33	50
649659456	64	37.74	9	61	20	72	1.0e-05	41.9	COG0690	Preprotein translocase subunit SecE	73
649659457	179	47.46	4	179	3	177	2.0e-46	178	COG0250	Transcription antitermination factor NusG	178
649659458	140	71.74	2	139	1	138	2.0e-50	191	COG0080	Ribosomal protein L11	141
649659459	230	57.78	1	223	4	228	3.0e-75	275	COG0081	Ribosomal protein L1	228
649659460	311	66.14	185	311	1	124	3.0e-29	122	COG0222	Ribosomal protein L7/L12	124
649659462	1396	49.53	19	835	6	808	0.0e+00	874	COG0086	DNA-directed RNA polymerase, beta' subunit/160 kD subunit	808
649659464	123	78.05	1	123	7	129	2.0e-48	184	COG0048	Ribosomal protein S12	129
649659465	157	62.24	8	150	7	148	1.0e-53	202	COG0049	Ribosomal protein S7	148
649659466	693	67.24	1	692	1	693	0.0e+00	980	COG0480	Translation elongation factor EF-G, a GTPase	697
649659467	401	74.06	1	401	1	394	0.0e+00	660	COG0050	Translation elongation factor EF-Tu, a GTPase	394
649659468	103	67.68	5	103	4	102	2.0e-33	133	COG0051	Ribosomal protein S10	104
649659469	206	50.24	4	205	3	211	2.0e-58	218	COG0087	Ribosomal protein L3	218
649659470	207	44.55	1	207	1	211	3.0e-47	181	COG0088	Ribosomal protein L4	214
649659471	97	46.81	5	97	1	94	1.0e-20	91.4	COG0089	Ribosomal protein L23	94
649659472	275	64.13	1	275	1	275	1.0e-103	369	COG0090	Ribosomal protein L2	275
649659473	95	65.52	1	87	1	87	2.0e-34	136	COG0185	Ribosomal protein S19	93
649659474	117	51.4	3	109	10	116	3.0e-26	110	COG0091	Ribosomal protein L22	120
649659475	222	62.31	12	208	1	199	7.0e-72	263	COG0092	Ribosomal protein S3	233
649659476	138	58.7	1	136	2	139	2.0e-45	174	COG0197	Ribosomal protein L16/L10AE	146
649659477	73	52.54	4	62	6	64	3.0e-08	49.9	COG0255	Ribosomal protein L29	69
649659478	89	54.43	7	85	7	85	4.0e-17	79.5	COG0186	Ribosomal protein S17	87
649659479	122	72.13	1	122	1	122	3.0e-48	183	COG0093	Ribosomal protein L14	122
649659480	108	49.52	5	108	2	104	3.0e-16	76.9	COG0198	Ribosomal protein L24	104
649659481	194	63.48	16	193	1	178	2.0e-73	268	COG0094	Ribosomal protein L5	180
649659482	61	52.46	1	61	1	61	1.0e-10	58.3	COG0199	Ribosomal protein S14	61
649659483	131	47.33	1	131	2	132	2.0e-38	151	COG0096	Ribosomal protein S8	132
649659484	178	51.96	1	178	1	178	3.0e-48	184	COG0097	Ribosomal protein L6P/L9E	178
649659485	121	59.32	6	121	8	125	2.0e-29	121	COG0256	Ribosomal protein L18	125
649659486	167	59.87	1	156	15	171	7.0e-47	180	COG0098	Ribosomal protein S5	181
649659487	69	51.85	14	67	1	54	5.0e-11	59.4	COG1841	Ribosomal protein L30/L7E	55
649659488	149	53.64	1	146	1	151	1.0e-34	139	COG0200	Ribosomal protein L15	152
649659489	437	50.69	2	428	3	432	4.0e-119	421	COG0201	Preprotein translocase subunit SecY	436
649659490	218	41.98	1	212	1	177	2.0e-43	169	COG0563	Adenylate kinase or related kinase	178
649659491	251	49.39	1	242	2	246	4.0e-83	301	COG0024	Methionine aminopeptidase	255
649659492	72	70.83	1	72	1	72	6.0e-26	109	COG0361	Translation initiation factor IF-1	75
649659494	129	62.5	1	120	1	120	2.0e-37	147	COG0099	Ribosomal protein S13	121
649659495	127	67.2	3	127	5	129	2.0e-44	170	COG0100	Ribosomal protein S11	129
649659496	208	49.05	1	208	1	205	2.0e-54	205	COG0522	Ribosomal protein S4 or related protein	205
649659497	333	49.06	8	325	1	313	9.0e-92	330	COG0202	DNA-directed RNA polymerase, alpha subunit/40 kD subunit	317
649659498	148	56.9	1	116	1	116	4.0e-36	144	COG0203	Ribosomal protein L17	116
649659501	241	62.76	5	241	5	243	3.0e-98	351	COG1137	ABC-type lipopolysaccharide export system, ATPase component	243
649659502	505	38.34	1	505	1	444	8.0e-107	381	COG1508	DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog	444
649659503	183	37.76	1	96	1	98	1.0e-17	83	COG1544	Ribosome-associated translation inhibitor RaiA	110
649659504	293	49.65	9	292	1	285	8.0e-89	320	COG1660	RNase adaptor protein for sRNA GlmZ degradation, contains a P-loop ATPase domain	286
649659506	365	32.3	13	362	1	353	1.0e-63	237	COG4972	Tfp pilus assembly protein, ATPase PilM	354
649659507	184	23.95	1	166	4	164	2.0e-09	56.1	COG3166	Tfp pilus assembly protein PilN	206
649659508	207	25.24	2	206	7	211	1.0e-16	80	COG3167	Tfp pilus assembly protein PilO	211
649659509	209	26.92	76	196	32	160	3.0e-08	52.3	COG3168	Tfp pilus assembly protein PilP	170
649659511	385	49.58	13	369	4	359	2.0e-118	418	COG0337	3-dehydroquinate synthetase	360
649659516	589	40.43	309	581	3	268	5.0e-69	255	COG0171	NH3-dependent NAD+ synthetase	268
649659518	442	56.9	39	442	2	403	3.0e-117	415	COG0004	Ammonia channel protein AmtB	409
649659519	112	64.29	1	112	1	112	7.0e-38	148	COG0347	Nitrogen regulatory protein PII	112
649659520	894	33.98	21	879	9	856	0.0e+00	543	COG2844	UTP:GlnB (protein PII) uridylyltransferase	867
649659521	469	46.53	1	469	1	443	0.0e+00	508	COG0174	Glutamine synthetase	443
649659522	276	36.96	1	254	4	258	6.0e-48	184	COG2116	Formate/nitrite transporter FocA, FNT family	265
649659523	146	41.22	1	146	4	151	8.0e-35	139	COG1513	Cyanate lyase	151
649659525	531	34.75	3	496	8	487	3.0e-107	382	COG0155	Sulfite reductase, beta subunit (hemoprotein)	510
649659530	97	23.81	4	84	3	86	9.0e-06	41.8	COG2026	mRNA-degrading endonuclease RelE, toxin component of the RelBE toxin-antitoxin system	90
649659531	98	35.06	3	77	4	80	1.0e-06	45	COG2161	Antitoxin component YafN of the YafNO toxin-antitoxin module, PHD/YefM family	86
649659536	546	49.45	1	534	2	524	0.0e+00	494	COG0459	Chaperonin GroEL (HSP60 family)	524
649659537	100	50.54	14	97	1	93	2.0e-20	90.6	COG0234	Co-chaperonin GroES (HSP10)	96
649659539	340	33.54	14	330	22	333	7.0e-51	194	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
649659540	413	34.88	13	387	7	393	2.0e-59	223	COG2223	Nitrate/nitrite transporter NarK	417
649659541	402	61.08	3	205	1	202	2.0e-79	290	COG0108	3,4-dihydroxy-2-butanone 4-phosphate synthase	203
649659542	180	50.99	1	151	1	151	6.0e-49	186	COG0054	6,7-dimethyl-8-ribityllumazine synthase (Riboflavin synthase beta chain)	152
649659543	157	37.93	1	138	7	151	8.0e-33	133	COG0781	Transcription termination factor NusB	151
649659544	444	48.4	1	431	1	438	0.0e+00	498	COG0015	Adenylosuccinate lyase	438
649659545	264	21.82	47	263	20	230	2.0e-18	86.5	COG3253	Chlorite dismutase	230
649659546	237	51.53	9	235	6	234	8.0e-78	283	COG0152	Phosphoribosylaminoimidazole-succinocarboxamide synthase	247
649659548	79	51.28	1	78	2	79	1.0e-23	101	COG1828	Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component	83
649659549	252	54.78	13	241	3	231	4.0e-87	314	COG0047	Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain	231
649659550	748	52.14	6	718	14	727	0.0e+00	925	COG0046	Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain	743
649659551	476	56.03	13	469	1	463	0.0e+00	642	COG0034	Glutamine phosphoribosylpyrophosphate amidotransferase	470
649659556	181	29.75	28	169	5	155	6.0e-13	67.6	COG1225	Peroxiredoxin	157
649659558	198	20.87	1	178	5	206	2.0e-03	36.4	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
649659565	846	48.06	135	827	11	672	0.0e+00	724	COG1200	RecG-like helicase	677
649659574	259	43.88	8	241	4	239	4.0e-44	171	COG1354	Chromatin segregation and condensation protein Rec8/ScpA/Scc1, kleisin family	248
649659575	301	48.39	50	235	1	184	3.0e-43	169	COG1386	Chromosome segregation and condensation protein ScpB	184
649659578	488	31.96	256	474	1	169	2.0e-31	130	COG0516	IMP dehydrogenase/GMP reductase	170
649659579	518	67.61	201	518	1	315	0.0e+00	530	COG0519	GMP synthase, PP-ATPase domain/subunit	315
649659580	420	49.8	1	240	1	247	5.0e-75	275	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
649659581	587	62.2	4	583	2	582	0.0e+00	894	COG0173	Aspartyl-tRNA synthetase	585
649659582	378	56.71	2	359	1	364	0.0e+00	515	COG0082	Chorismate synthase	369
649659583	156	55.03	1	146	3	151	6.0e-48	183	COG0328	Ribonuclease HI	154
649659584	265	38.89	2	230	26	255	2.0e-51	196	COG1119	ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA	257
649659585	344	26	17	342	7	339	1.0e-24	107	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
649659586	184	33.72	7	175	9	174	1.0e-21	96.2	COG3065	Starvation-inducible outer membrane lipoprotein	191
649659587	288	53.92	1	286	1	292	7.0e-97	347	COG2321	Predicted metalloprotease	295
649659590	195	39.09	3	192	59	242	2.0e-49	188	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
649659591	153	34.78	30	142	11	125	2.0e-20	91.5	COG3439	Uncharacterized conserved protein, DUF302 family	137
649659594	291	26.74	18	272	3	254	3.0e-21	95.9	COG3000	Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily	271
649659596	364	27.43	1	344	1	344	2.0e-28	120	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
649659597	342	30.29	7	221	2	237	7.0e-34	138	COG2041	Periplasmic DMSO/TMAO reductase YedYZ, molybdopterin-dependent catalytic subunit	271
649659603	226	51.13	6	224	4	223	1.0e-80	292	COG0692	Uracil DNA glycosylase	223
649659604	262	45.54	38	259	23	246	9.0e-65	240	COG3338	Carbonic anhydrase	250
649659607	151	19.72	10	139	60	201	4.0e-09	54.5	COG2854	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic MlaC component	202
649659615	106	52.83	1	105	4	109	7.0e-34	135	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
649659617	445	32.87	24	304	1	275	7.0e-21	95.5	COG4584	Transposase	278
649659618	259	48.41	1	249	2	253	7.0e-54	204	COG1484	DNA replication protein DnaC	254
649659620	297	28.91	41	287	8	254	1.0e-42	167	COG1013	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, beta subunit	294
649659627	431	45.5	7	410	29	436	5.0e-110	391	COG0513	Superfamily II DNA and RNA helicase	513
649659630	517	36.83	7	504	32	546	5.0e-111	395	COG3604	Transcriptional regulator containing GAF, AAA-type ATPase, and DNA-binding Fis domains	550
649659634	364	21.78	4	305	3	291	6.0e-20	92.1	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
649659636	411	25.87	110	395	16	276	1.0e-22	101	COG0741	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)	296
649659637	187	22.1	14	184	25	202	1.0e-08	53	COG2854	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic MlaC component	202
649659638	249	30.28	12	228	1	209	1.0e-28	120	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
649659643	214	39.23	3	210	2	210	1.0e-48	186	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
649659650	289	33.33	20	289	14	284	7.0e-53	200	COG1398	Fatty-acid desaturase	289
649659653	312	42.21	7	311	3	308	5.0e-70	258	COG1560	Lauroyl/myristoyl acyltransferase	308
649659656	291	31.68	29	290	7	263	2.0e-35	143	COG0767	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, permease component MlaE	267
649659657	243	36.49	23	243	26	246	9.0e-39	153	COG1127	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, ATPase component MlaF	263
649659658	329	24.38	15	289	9	281	6.0e-17	82.1	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
649659659	266	23.96	3	219	48	236	1.0e-03	37.6	COG3063	Tfp pilus assembly protein PilF	250
649659660	770	40.12	263	767	15	497	2.0e-129	456	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
649659661	543	45.17	1	533	26	496	0.0e+00	529	COG0442	Prolyl-tRNA synthetase	500
649659663	386	57.07	1	381	1	380	0.0e+00	527	COG0743	1-deoxy-D-xylulose 5-phosphate reductoisomerase	385
649659664	282	37.26	19	278	5	263	4.0e-29	121	COG0575	CDP-diglyceride synthetase	265
649659665	261	54.36	15	255	5	245	8.0e-84	303	COG0020	Undecaprenyl pyrophosphate synthase	245
649659666	478	40.78	19	476	5	454	4.0e-111	395	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
649659667	452	40.18	13	451	4	453	9.0e-90	324	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
649659668	184	40.22	1	184	1	173	2.0e-41	162	COG1881	Uncharacterized conserved protein, phosphatidylethanolamine-binding protein (PEBP) family	174
649659670	223	42.5	1	187	3	201	1.0e-41	163	COG1573	Uracil-DNA glycosylase	202
649659671	436	21.68	5	431	3	459	1.0e-23	105	COG3349	Uncharacterized conserved protein, contains NAD-binding domain and a Fe-S cluster	485
649659672	303	39.1	12	297	2	287	9.0e-53	200	COG1562	Phytoene/squalene synthetase	288
649659673	310	24.23	2	289	54	315	1.0e-26	114	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
649659674	235	33.78	4	227	2	216	6.0e-35	141	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
649659677	137	48.18	1	136	1	137	1.0e-42	165	COG0432	Thiamin phosphate synthase YjbQ, UPF0047 family	137
649659681	278	38.82	12	261	14	258	2.0e-56	212	COG0631	Serine/threonine protein phosphatase PrpC	262
649659682	469	33.92	201	460	2	277	7.0e-44	171	COG0515	Serine/threonine protein kinase	384
649659683	282	39.6	1	249	1	247	6.0e-46	177	COG0613	Predicted metal-dependent phosphoesterase TrpH, contains PHP domain	258
649659684	309	34.71	1	120	1	121	4.0e-19	89.1	COG1539	Dihydroneopterin aldolase	121
649659693	909	22.68	136	760	58	637	6.0e-57	216	COG1203	CRISPR/Cas system-associated endonuclease/helicase Cas3	733
649659699	306	22.36	13	305	1	320	7.0e-41	161	COG1518	CRISPR/Cas system-associated endonuclease Cas1	327
649659702	64	50.94	1	53	2	53	5.0e-10	56.2	COG1598	Predicted nuclease of the RNAse H fold, HicB family	73
649659704	401	22.41	40	366	34	370	5.0e-20	92.4	COG3550	Serine/threonine protein kinase HipA, toxin component of the HipAB toxin-antitoxin module	392
649659706	343	26.96	70	343	3	281	3.0e-23	103	COG4395	Predicted lipid-binding transport protein, Tim44 family	281
649659709	227	50	1	224	1	229	9.0e-63	233	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
649659710	481	37.31	152	476	17	334	3.0e-44	173	COG0642	Signal transduction histidine kinase	336
649659714	422	31.2	17	419	9	414	5.0e-68	251	COG2733	Uncharacterized membrane-anchored protein YjiN, DUF445 family	415
649659716	470	27.9	23	441	2	395	2.0e-51	196	COG1301	Na+/H+-dicarboxylate symporter	415
649659718	165	54.6	1	163	1	157	6.0e-55	206	COG0315	Molybdenum cofactor biosynthesis enzyme	157
649659719	87	27.38	1	83	1	84	1.0e-09	54.9	COG1977	Molybdopterin converting factor, small subunit	84
649659720	157	41.48	21	155	6	139	7.0e-36	143	COG0314	Molybdopterin synthase catalytic subunit	149
649659721	354	45.51	13	324	2	311	4.0e-93	334	COG2896	Molybdenum cofactor biosynthesis enzyme MoaA	322
649659724	278	59.86	1	276	1	279	6.0e-114	403	COG0777	Acetyl-CoA carboxylase beta subunit	294
649659726	431	43.39	1	424	2	424	3.0e-114	405	COG0285	Folylpolyglutamate synthase/Dihydropteroate synthase	427
649659730	565	45.91	1	559	1	557	0.0e+00	507	COG0497	DNA repair ATPase RecN	557
649659731	380	31.35	13	363	14	350	2.0e-46	180	COG3437	Response regulator c-di-GMP phosphodiesterase, RpfG family, contains REC and HD-GYP domains	360
649659732	470	49.67	1	458	3	460	0.0e+00	497	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
649659737	268	38.4	10	254	8	247	5.0e-50	191	COG0631	Serine/threonine protein phosphatase PrpC	262
649659738	257	27.51	1	244	3	269	7.0e-29	120	COG3359	Uncharacterized conserved protein YprB, contains RNaseH-like and TPR domains	278
649659739	136	36.51	5	128	1	125	2.0e-18	84.7	COG2164	Uncharacterized protein	126
649659743	155	66.23	2	155	1	154	6.0e-59	219	COG1225	Peroxiredoxin	157
649659746	259	60.08	1	253	2	254	2.0e-102	365	COG0623	Enoyl-[acyl-carrier-protein] reductase (NADH)	259
649659754	196	38.12	10	190	1	181	2.0e-31	128	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
649659767	365	41.26	3	344	6	352	3.0e-100	358	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
649659768	269	45.69	2	268	20	286	2.0e-64	239	COG4208	ABC-type sulfate transport system, permease component	287
649659769	293	46.12	11	268	15	272	6.0e-58	217	COG0555	ABC-type sulfate transport system, permease component	274
649659770	351	36.05	7	344	13	343	6.0e-79	287	COG1613	ABC-type sulfate transport system, periplasmic component	348
649659771	141	43.48	1	138	1	131	1.0e-33	135	COG1959	DNA-binding transcriptional regulator, IscR family	150
649659778	306	67.69	1	290	5	298	0.0e+00	522	COG0752	Glycyl-tRNA synthetase, alpha subunit	298
649659779	724	42.19	19	719	3	689	0.0e+00	683	COG0751	Glycyl-tRNA synthetase, beta subunit	691
649659781	949	27.17	6	895	1	738	0.0e+00	573	COG0574	Phosphoenolpyruvate synthase/pyruvate phosphate dikinase	740
649659782	373	46.36	147	366	1	212	3.0e-52	199	COG1985	Pyrimidine reductase, riboflavin biosynthesis	218
649659786	391	21.73	8	387	15	387	2.0e-19	90.7	COG2814	Predicted arabinose efflux permease, MFS family	394
649659788	218	52.28	1	196	1	195	6.0e-64	237	COG0307	Riboflavin synthase alpha chain	204
649659790	629	45.52	70	626	1	528	0.0e+00	663	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
649659795	476	22.86	52	437	56	406	3.0e-24	106	COG3014	Uncharacterized protein	449
649659801	276	53.56	5	271	2	266	2.0e-75	275	COG0345	Pyrroline-5-carboxylate reductase	266
649659816	550	33.94	1	542	1	551	2.0e-121	429	COG3961	TPP-dependent 2-oxoacid decarboxylase, includes indolepyruvate decarboxylase	557
649659817	434	44.33	61	433	14	392	8.0e-96	344	COG1092	23S rRNA G2069 N7-methylase RlmK or C1962 C5-methylase RlmI	393
649659818	668	42.39	14	613	4	617	0.0e+00	462	COG1297	Uncharacterized membrane protein, oligopeptide transporter (OPT) family	624
649659821	272	33.2	23	262	13	253	2.0e-38	152	COG0566	tRNA G18 (ribose-2'-O)-methylase SpoU	260
649659822	458	56.67	6	457	2	454	0.0e+00	594	COG1066	Predicted ATP-dependent serine protease	456
649659824	274	35.78	9	236	3	220	7.0e-33	134	COG1214	tRNA A37 threonylcarbamoyladenosine modification protein TsaB	220
649659825	166	28.66	1	153	7	170	1.0e-18	86.2	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
649659827	256	37.55	2	230	7	242	4.0e-42	164	COG0805	Sec-independent protein secretion pathway component TatC	255
649659829	169	53.02	22	167	9	151	2.0e-45	175	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
649659831	472	24.54	13	446	14	444	4.0e-33	136	COG1538	Outer membrane protein TolC	457
649659832	432	25.71	60	393	26	370	1.0e-24	107	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
649659833	1089	29.04	1	1069	1	1006	0.0e+00	633	COG0841	Multidrug efflux pump subunit AcrB	1009
649659834	142	31.93	1	119	4	116	2.0e-15	75.3	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
649659837	420	16.76	69	414	62	391	5.0e-07	49.4	COG2814	Predicted arabinose efflux permease, MFS family	394
649659838	408	17.87	61	404	63	387	7.0e-06	45.6	COG2814	Predicted arabinose efflux permease, MFS family	394
649659842	249	18.57	4	192	6	211	2.0e-03	36.1	COG2834	Outer membrane lipoprotein-sorting protein	211
649659850	370	64.56	1	282	1	277	5.0e-87	314	COG0468	RecA/RadA recombinase	279
649659851	165	30.71	21	153	23	160	3.0e-13	68	COG2137	SOS response regulatory protein OraA/RecX, interacts with RecA	174
649659852	876	52.83	1	874	4	879	0.0e+00	1064	COG0013	Alanyl-tRNA synthetase	879
649659853	203	47.45	3	138	1	137	3.0e-37	148	COG0816	RNase H-fold protein, predicted Holliday junction resolvase in Firmicutes and mycoplasms, involved in anti-termination at Rho-dependent terminators	141
649659854	350	40.77	1	334	4	338	8.0e-85	307	COG1559	Cell division protein YceG, involved in septum cleavage	342
649659855	229	53	8	222	6	222	2.0e-64	238	COG0274	Deoxyribose-phosphate aldolase	228
649659856	384	37.44	2	382	1	397	7.0e-77	281	COG1015	Phosphopentomutase	397
649659863	92	38.3	1	92	1	94	1.0e-19	88.4	COG3549	Plasmid maintenance system killer protein	94
649659864	101	44.68	1	94	1	90	6.0e-18	82.3	COG3093	Plasmid maintenance system antidote protein VapI, contains XRE-type HTH domain	104
649659867	153	29.05	6	153	1	130	3.0e-14	71.5	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
649659869	322	26.1	14	320	17	332	4.0e-28	118	COG4447	Uncharacterized protein related to plant photosystem II stability/assembly factor	339
649659870	245	35.92	1	243	3	246	1.0e-45	177	COG1385	16S rRNA U1498 N3-methylase RsmE	246
649659871	370	52.66	1	370	1	370	1.0e-122	433	COG0484	DnaJ-class molecular chaperone with C-terminal Zn finger domain	371
649659872	643	61.56	1	600	4	579	0.0e+00	694	COG0443	Molecular chaperone DnaK (HSP70)	579
649659873	184	41.46	17	179	27	190	3.0e-36	144	COG0576	Molecular chaperone GrpE (heat shock protein)	193
649659874	256	45.67	1	253	1	251	5.0e-66	244	COG1521	Pantothenate kinase type III	251
649659875	290	35.83	36	289	2	237	3.0e-51	195	COG0340	Biotin-(acetyl-CoA carboxylase) ligase	238
649659876	293	54.12	9	285	6	280	5.0e-83	301	COG0157	Nicotinate-nucleotide pyrophosphorylase	280
649659877	920	51.43	6	909	1	877	0.0e+00	1117	COG0525	Valyl-tRNA synthetase	877
649659880	251	30.17	15	251	2	229	2.0e-26	112	COG1011	FMN phosphatase YigB, HAD superfamily	229
649659881	243	46.22	12	243	7	244	3.0e-73	268	COG0846	NAD-dependent protein deacetylase, SIR2 family	250
649659882	454	40.13	1	298	1	298	1.0e-71	264	COG1893	Ketopantoate reductase	307
649659883	445	36.18	6	443	13	454	1.0e-65	243	COG0534	Na+-driven multidrug efflux pump	455
649659884	501	18.85	16	500	4	470	2.0e-06	47.3	COG2251	Predicted nuclease, RecB family	474
649659887	3120	41.34	2018	2663	1	642	0.0e+00	488	COG1020	Non-ribosomal peptide synthetase component F	642
649659888	565	35.06	6	564	2	546	4.0e-113	402	COG4615	ABC-type siderophore export system, fused ATPase and permease components	546
649659889	241	34.16	30	190	24	180	3.0e-33	135	COG2091	Phosphopantetheinyl transferase	223
649659890	162	54.48	8	151	8	152	7.0e-47	179	COG0590	tRNA(Arg) A34 adenosine deaminase TadA	152
649659892	217	34.95	29	214	2	182	5.0e-25	107	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
649659898	191	24.82	7	135	3	134	6.0e-09	54.1	COG1225	Peroxiredoxin	157
649659900	258	19.33	26	256	1	260	7.0e-10	57.9	COG0708	Exonuclease III	261
649659901	285	24.91	16	272	25	288	4.0e-33	135	COG1639	HD-like signal output (HDOD) domain, no enzymatic activity	289
649659903	231	24.53	21	231	16	226	3.0e-14	72.3	COG1814	Predicted Fe2+/Mn2+ transporter, VIT1/CCC1 family	229
649659909	1040	46.52	1	1015	2	1015	0.0e+00	1037	COG3696	Cu/Ag efflux pump CusA	1027
649659910	390	26.32	49	381	33	363	7.0e-23	101	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
649659911	419	27.18	36	416	44	443	5.0e-28	119	COG1538	Outer membrane protein TolC	457
649659915	107	24.51	7	101	1	101	2.0e-09	54.4	COG0347	Nitrogen regulatory protein PII	112
649659916	657	26.91	321	657	20	358	6.0e-27	116	COG3852	Signal transduction histidine kinase, nitrogen specific	363
649659917	468	44.3	1	465	3	452	4.0e-124	438	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
649659926	276	26.05	52	265	24	224	4.0e-14	71.9	COG2801	Transposase InsO and inactivated derivatives	232
649659939	412	49.51	1	403	3	386	0.0e+00	466	COG0448	ADP-glucose pyrophosphorylase	393
649659941	379	46.01	18	379	1	352	4.0e-107	381	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
649659942	267	51.91	1	260	20	281	3.0e-65	242	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
649659943	257	51.76	2	255	7	261	2.0e-57	215	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
649659944	349	40.28	1	348	2	361	1.0e-83	303	COG0687	Spermidine/putrescine-binding periplasmic protein	363
649659945	448	24.72	16	448	1	448	3.0e-37	149	COG1538	Outer membrane protein TolC	457
649659946	381	30.92	38	379	29	363	8.0e-22	98.3	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
649659947	1034	41.01	1	1023	1	1027	0.0e+00	938	COG3696	Cu/Ag efflux pump CusA	1027
649659949	176	49.42	1	170	1	165	5.0e-51	193	COG0242	Peptide deformylase	168
649659950	559	42.4	1	559	14	567	0.0e+00	504	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
649659959	267	49.41	1	249	1	253	1.0e-73	269	COG0476	Molybdopterin or thiamine biosynthesis adenylyltransferase	254
649659961	90	32.22	1	90	1	84	1.0e-10	58.4	COG1977	Molybdopterin converting factor, small subunit	84
649659962	413	38.37	1	400	3	397	2.0e-95	343	COG0498	Threonine synthase	411
649659963	275	51.97	1	249	1	254	2.0e-74	272	COG0476	Molybdopterin or thiamine biosynthesis adenylyltransferase	254
649659964	309	60.87	6	302	2	299	9.0e-118	416	COG0031	Cysteine synthase	300
649659965	66	42.42	1	65	3	68	3.0e-08	50.2	COG2104	Sulfur carrier protein ThiS (thiamine biosynthesis)	68
649659969	425	29.49	8	394	3	385	1.0e-40	161	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
649659971	245	26	17	243	11	259	1.0e-20	93.5	COG1512	Uncharacterized membrane protein YgcG, contains a TPM-fold domain	271
649659977	314	30.03	7	296	3	283	6.0e-21	95	COG3547	Transposase	303
649659979	128	23.73	9	122	9	126	4.0e-07	46.9	COG3631	Ketosteroid isomerase-related protein	133
649659981	285	25.34	149	285	6	151	7.0e-09	54.6	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
649659986	185	20	25	174	6	141	2.0e-03	36.1	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
649659995	392	38.62	1	384	29	416	1.0e-93	336	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
649659997	75	32.31	1	62	8	71	1.0e-05	41.6	COG2331	Predicted nucleic acid-binding protein, contains Zn-ribbon domain	82
649660002	296	31.43	2	295	23	313	1.0e-40	160	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
649660003	250	24.8	1	241	1	225	2.0e-12	66.5	COG5424	Pyrroloquinoline quinone (PQQ) biosynthesis protein C	242
649660009	1227	56.5	329	1193	1	842	0.0e+00	1107	COG1410	Methionine synthase I, cobalamin-binding domain	842
649660011	392	38.95	17	372	13	360	2.0e-78	286	COG3437	Response regulator c-di-GMP phosphodiesterase, RpfG family, contains REC and HD-GYP domains	360
649660012	247	56.12	9	244	9	230	7.0e-72	263	COG0689	Ribonuclease PH	230
649660013	204	46.15	1	195	2	193	3.0e-55	208	COG0127	Inosine/xanthosine triphosphate pyrophosphatase, all-alpha NTP-PPase family	194
649660018	211	36.22	1	190	1	193	3.0e-56	211	COG0450	Alkyl hydroperoxide reductase subunit AhpC (peroxiredoxin)	194
649660021	730	20.16	195	562	61	423	2.0e-25	111	COG1032	Radical SAM superfamily enzyme YgiQ, UPF0313 family	490
649660024	370	30.29	37	364	62	399	5.0e-44	171	COG1850	Ribulose 1,5-bisphosphate carboxylase, large subunit, or a RuBisCO-like protein	429
649660025	269	38.82	34	269	2	217	1.0e-47	183	COG1878	Kynurenine formamidase	218
649660027	190	22.55	6	190	10	210	1.0e-11	63	COG2761	Predicted dithiol-disulfide isomerase, DsbA family	225
649660031	139	48.84	12	139	1	129	2.0e-50	191	COG0229	Peptide methionine sulfoxide reductase MsrB	140
649660032	798	51.82	12	778	10	773	0.0e+00	951	COG0466	ATP-dependent Lon protease, bacterial type	782
649660034	508	36.68	20	505	15	486	1.0e-117	417	COG0380	Trehalose-6-phosphate synthase	486
649660035	389	39.26	8	381	5	381	1.0e-98	353	COG0116	23S rRNA G2445 N2-methylase RlmL	381
649660036	180	28.97	29	167	1	145	1.0e-21	96.3	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
649660037	102	24.73	1	89	4	96	5.0e-10	56.4	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
649660038	91	25.32	4	81	3	81	3.0e-06	43.3	COG2026	mRNA-degrading endonuclease RelE, toxin component of the RelBE toxin-antitoxin system	90
649660040	714	29.81	5	486	3	422	6.0e-59	222	COG0286	Type I restriction-modification system, DNA methylase subunit	489
649660041	373	49.38	118	279	1	159	2.0e-46	180	COG4804	Predicted nuclease of restriction endonuclease-like (RecB) superfamily,  DUF1016 family	159
649660042	452	17.28	26	405	1	391	5.0e-18	86.3	COG0732	Restriction endonuclease S subunit	391
649660043	1007	21.79	44	1006	17	921	2.0e-113	404	COG0610	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases ...	962
649660044	195	27.39	23	174	25	181	2.0e-15	75.9	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
649660046	266	21.01	9	263	18	258	1.0e-13	70.5	COG5340	Transcriptional regulator, predicted component of viral defense system	269
649660048	419	23.22	1	395	1	390	5.0e-27	115	COG0420	DNA repair exonuclease SbcCD nuclease subunit	390
649660049	1176	20.45	430	1160	254	971	3.0e-28	121	COG4717	Uncharacterized protein YhaN	984
649660050	1013	39.22	464	717	94	336	9.0e-45	176	COG0642	Signal transduction histidine kinase	336
649660051	239	35.48	1	239	1	246	2.0e-47	182	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
649660052	205	26.78	15	190	25	207	4.0e-11	61.8	COG1584	Succinate-acetate transporter protein	207
649660057	131	27.64	1	118	5	127	7.0e-11	59.7	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
649660061	452	41.72	9	444	4	434	6.0e-123	434	COG0621	tRNA A37 methylthiotransferase MiaB	437
649660062	447	37.5	4	436	1	437	8.0e-113	400	COG0621	tRNA A37 methylthiotransferase MiaB	437
649660064	287	31.29	1	143	6	152	6.0e-11	61.5	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
649660067	172	35.1	12	160	5	153	7.0e-17	80.4	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
649660069	311	35.53	1	144	2	153	1.0e-16	80.8	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
649660072	149	42.18	3	149	11	157	1.0e-34	139	COG1905	NADH:ubiquinone oxidoreductase 24 kD subunit (chain E)	160
649660073	498	52.29	83	492	2	416	0.0e+00	512	COG1894	NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F)	424
649660074	908	40.08	1	901	6	947	0.0e+00	948	COG3383	Predicted molibdopterin-dependent oxidoreductase YjgC	978
649660075	280	45.42	15	275	4	259	6.0e-52	198	COG2116	Formate/nitrite transporter FocA, FNT family	265
649660076	421	21.81	107	402	107	387	1.0e-05	44.4	COG2814	Predicted arabinose efflux permease, MFS family	394
649660079	1180	21.39	6	710	1	578	2.0e-75	278	COG0209	Ribonucleotide reductase alpha subunit	696
649660081	343	18.96	54	341	31	348	1.0e-11	64	COG4249	Uncharacterized protein, contains caspase domain	380
649660093	595	26.38	11	569	2	533	4.0e-74	272	COG2831	Hemolysin activation/secretion protein	554
649660094	280	20.34	42	218	18	182	8.0e-13	67.9	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
649660095	859	39.62	454	859	8	420	3.0e-77	283	COG4995	Uncharacterized conserved protein, contains CHAT domain	420
649660097	325	29.51	19	194	32	213	1.0e-16	80.6	COG2114	Adenylate cyclase, class 3	227
649660098	262	40.08	5	261	1	251	3.0e-56	212	COG0631	Serine/threonine protein phosphatase PrpC	262
649660099	337	31.48	45	336	4	303	6.0e-21	95.3	COG3391	DNA-binding beta-propeller fold protein YncE	381
649660101	1045	24.3	553	1043	14	418	7.0e-28	120	COG4995	Uncharacterized conserved protein, contains CHAT domain	420
649660109	417	22.27	1	417	1	430	8.0e-21	95.1	COG3456	Predicted component of the type VI protein secretion system, contains a FHA domain	430
649660110	147	26.77	1	122	10	134	3.0e-18	84.6	COG3521	Predicted component of the type VI protein secretion system	159
649660111	446	32.06	1	443	1	443	4.0e-81	295	COG3522	Predicted component of the type VI protein secretion system	446
649660112	232	32.74	12	231	41	260	1.0e-34	140	COG3455	Type VI protein secretion system component VasF	262
649660113	1209	28.22	8	1204	1	1183	0.0e+00	603	COG3523	Type VI protein secretion system component VasK	1188
649660115	266	39.46	1	260	6	265	1.0e-53	202	COG4455	Protein of avirulence locus involved in temperature-dependent protein secretion	273
649660116	372	25.83	7	361	2	344	8.0e-24	105	COG3515	Predicted component of the type VI protein secretion system	346
649660117	177	48.48	4	168	2	164	2.0e-48	185	COG3516	Predicted component of the type VI protein secretion system	169
649660118	497	60.2	1	495	1	494	0.0e+00	744	COG3517	Predicted component of the type VI protein secretion system	495
649660119	151	28.76	10	147	6	158	2.0e-16	78.8	COG3157	Type VI protein secretion system component Hcp (secreted cytotoxin)	162
649660121	135	22.31	8	125	3	120	2.0e-07	48.5	COG3755	Uncharacterized conserved protein YecT, DUF1311 family	127
649660122	278	39.47	126	277	7	156	2.0e-21	96.2	COG3518	Predicted component of the type VI protein secretion system	157
649660123	604	44	1	604	1	621	0.0e+00	565	COG3519	Type VI protein secretion system component VasA	621
649660124	354	39.53	1	344	1	333	8.0e-75	274	COG3520	Predicted component of the type VI protein secretion system	335
649660127	750	41.35	4	550	7	549	0.0e+00	591	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
649660130	374	36.41	1	367	1	365	3.0e-84	305	COG5351	Uncharacterized protein	367
649660131	345	20.06	1	305	2	356	3.0e-11	63	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
649660138	445	32.87	24	304	1	275	7.0e-21	95.5	COG4584	Transposase	278
649660139	259	48.41	1	249	2	253	7.0e-54	204	COG1484	DNA replication protein DnaC	254
649660142	87	39.29	5	86	3	84	3.0e-16	76.5	COG4115	Toxin component of the Txe-Axe toxin-antitoxin module, Txe/YoeB family	84
649660143	80	33.73	1	80	3	85	1.0e-09	54.6	COG2161	Antitoxin component YafN of the YafNO toxin-antitoxin module, PHD/YefM family	86
649660149	523	32.42	157	511	10	372	2.0e-60	227	COG3517	Predicted component of the type VI protein secretion system	495
649660151	276	28.84	52	265	24	224	1.0e-12	67.3	COG2801	Transposase InsO and inactivated derivatives	232
649660154	256	24.7	15	178	4	159	2.0e-09	56.6	COG4380	Uncharacterized protein	216
649660155	315	21.01	1	215	1	219	8.0e-08	51.5	COG1462	Curli biogenesis system outer membrane secretion channel CsgG	252
649660156	448	46.81	1	448	3	457	0.0e+00	475	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
649660157	438	25.18	166	438	78	332	1.0e-22	101	COG0642	Signal transduction histidine kinase	336
649660158	571	26.32	9	366	1	377	4.0e-41	163	COG0515	Serine/threonine protein kinase	384
649660161	872	26.5	9	337	1	348	3.0e-45	177	COG0515	Serine/threonine protein kinase	384
649660162	335	35.14	95	204	6	115	4.0e-07	49.3	COG3018	Uncharacterized protein	115
649660164	572	28.27	45	567	43	552	3.0e-84	306	COG2831	Hemolysin activation/secretion protein	554
649660166	821	40.44	420	819	11	417	4.0e-73	270	COG4995	Uncharacterized conserved protein, contains CHAT domain	420
649660167	370	65.11	8	370	2	365	0.0e+00	580	COG1980	Archaeal fructose 1,6-bisphosphatase	369
649660169	136	32.26	6	129	5	127	1.0e-14	72.6	COG4747	Uncharacterized conserved protein, contains tandem ACT domains	142
649660171	437	36.47	3	420	7	429	2.0e-81	296	COG1253	Hemolysin or related protein, contains CBS domains	429
649660172	675	49.93	6	673	2	667	0.0e+00	835	COG0272	NAD-dependent DNA ligase	667
649660176	498	47.8	24	496	1	460	0.0e+00	515	COG0147	Anthranilate/para-aminobenzoate synthases component I	462
649660177	187	62.77	1	187	3	190	1.0e-83	302	COG0512	Anthranilate/para-aminobenzoate synthase component II	191
649660178	349	53.25	10	347	1	338	1.0e-114	406	COG0547	Anthranilate phosphoribosyltransferase	338
649660179	274	49.62	3	266	1	254	7.0e-70	257	COG0134	Indole-3-glycerol phosphate synthase	254
649660181	210	45.93	2	206	1	206	2.0e-53	202	COG0135	Phosphoribosylanthranilate isomerase	208
649660182	396	68.72	4	393	3	391	0.0e+00	666	COG0133	Tryptophan synthase beta chain	396
649660183	266	49.43	1	262	1	262	8.0e-83	300	COG0159	Tryptophan synthase alpha chain	265
649660184	357	23.46	194	345	6	167	3.0e-07	50	COG2203	GAF domain	175
649660187	222	48.18	1	219	1	220	2.0e-77	282	COG1136	ABC-type lipoprotein export system, ATPase component	226
649660188	425	42.23	1	425	1	408	3.0e-90	325	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
649660189	493	59.31	3	493	9	502	0.0e+00	684	COG1190	Lysyl-tRNA synthetase (class II)	502
649660190	377	62.76	123	361	1	239	3.0e-103	368	COG1186	Protein chain release factor B	239
649660191	544	34.22	3	522	12	505	5.0e-85	308	COG0815	Apolipoprotein N-acyltransferase	518
649660204	67	35.82	1	67	3	69	6.0e-10	55.7	COG3360	Flavin-binding protein dodecin	71
649660209	662	43.02	7	536	9	507	0.0e+00	508	COG1389	DNA topoisomerase VI, subunit B	538
649660210	368	41.44	5	365	3	356	3.0e-91	328	COG1697	DNA topoisomerase VI, subunit A	356
649660219	550	60.19	25	549	1	524	0.0e+00	694	COG0033	Phosphoglucomutase	524
649660220	88	27.27	2	63	1	62	2.0e-04	37.6	COG0695	Glutaredoxin	80
649660222	1128	24.55	11	1124	6	1134	4.0e-108	386	COG1074	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)	1139
649660224	277	46.62	5	268	3	281	3.0e-65	242	COG0682	Prolipoprotein diacylglyceryltransferase	287
649660228	393	38.25	1	249	1	243	5.0e-35	142	COG2138	Sirohydrochlorin ferrochelatase	245
649660230	241	22.63	6	241	7	238	3.0e-18	85.7	COG1018	Ferredoxin-NADP reductase	266
649660232	368	42.9	8	362	5	360	7.0e-84	304	COG1903	Cobalamin biosynthesis protein CbiD	367
649660233	215	50	4	215	1	210	5.0e-54	203	COG2082	Precorrin isomerase	210
649660234	418	43.46	221	411	1	187	3.0e-48	186	COG2242	Precorrin-6B methylase 2	187
649660235	254	43.93	4	241	2	234	4.0e-55	208	COG2243	Precorrin-2 methylase	234
649660236	383	29.17	57	368	39	298	4.0e-28	119	COG2073	Cobalamin biosynthesis protein CbiG	298
649660237	277	52.19	1	250	1	247	2.0e-86	312	COG1010	Precorrin-3B methylase	249
649660239	263	55.6	1	249	3	252	1.0e-95	342	COG2875	Precorrin-4 methylase	254
649660240	489	49.8	8	251	4	244	6.0e-62	232	COG0007	Uroporphyrinogen-III methylase (siroheme synthase)	244
649660241	249	27.75	14	214	5	207	4.0e-23	101	COG0778	Nitroreductase	207
649660242	458	51.11	4	450	1	450	0.0e+00	512	COG1797	Cobyrinic acid a,c-diamide synthase	451
649660243	267	24.15	7	264	47	339	8.0e-22	97.6	COG3376	High-affinity nickel permease	342
649660244	684	16.08	6	684	26	768	5.0e-17	83.4	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
649660245	338	21.2	51	267	27	241	2.0e-12	67	COG5010	Flp pilus assembly protein TadD, contains TPR repeats	257
649660247	313	32.15	1	309	1	305	1.0e-42	166	COG4965	Flp pilus assembly protein TadB	309
649660248	450	53.58	58	406	10	353	3.0e-113	402	COG4962	Pilus assembly protein, ATPase of CpaF family	355
649660249	289	30	11	288	94	366	1.0e-26	113	COG4963	Flp pilus assembly protein, ATPase CpaE	366
649660250	359	27.56	21	172	16	169	7.0e-04	38.6	COG4961	Flp pilus assembly protein TadG	185
649660253	485	40.56	45	468	34	447	5.0e-92	331	COG4964	Flp pilus assembly protein, secretin CpaC	455
649660254	403	35.44	1	277	1	273	2.0e-30	127	COG3745	Flp pilus assembly protein CpaB	276
649660256	563	26.12	15	380	7	367	1.0e-29	124	COG2208	Serine phosphatase RsbU, regulator of sigma subunit	367
649660257	100	19.35	9	99	11	103	8.0e-09	51.9	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
649660259	276	28.38	52	272	24	231	3.0e-15	76.2	COG2801	Transposase InsO and inactivated derivatives	232
649660263	205	21.32	9	204	2	192	2.0e-07	49.6	COG1309	DNA-binding transcriptional regulator, AcrR family	201
649660264	280	37.59	8	268	4	265	9.0e-55	207	COG0300	Short-chain dehydrogenase	265
649660267	186	28.41	3	170	1	176	1.0e-13	69.8	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
649660268	255	31.47	7	249	6	249	7.0e-33	134	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
649660270	269	20.85	37	263	13	232	2.0e-11	63.1	COG2801	Transposase InsO and inactivated derivatives	232
649660275	445	32.87	24	304	1	275	7.0e-21	95.5	COG4584	Transposase	278
649660276	259	48.41	1	249	2	253	3.0e-54	205	COG1484	DNA replication protein DnaC	254
649660278	230	23.93	25	140	12	126	2.0e-04	39.5	COG3415	Transposase	138
649660279	101	48.86	1	88	1	84	2.0e-18	84.2	COG3093	Plasmid maintenance system antidote protein VapI, contains XRE-type HTH domain	104
649660280	120	45.76	1	118	1	117	4.0e-28	116	COG4683	Uncharacterized protein	120
649660289	1907	39.49	916	1578	1	642	0.0e+00	479	COG1020	Non-ribosomal peptide synthetase component F	642
649660291	1517	41.83	14	997	1	967	0.0e+00	800	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
649660292	565	37.96	7	550	6	538	3.0e-117	416	COG4615	ABC-type siderophore export system, fused ATPase and permease components	546
649660293	468	45.56	28	463	18	447	0.0e+00	482	COG0160	4-aminobutyrate aminotransferase or related aminotransferase	447
649660294	795	31.34	1	770	1	747	8.0e-96	345	COG2366	Acyl-homoserine lactone (AHL) acylase PvdQ	768
649660295	81	38.57	1	70	2	71	3.0e-15	73.5	COG3251	Uncharacterized conserved protein YbdZ, MbtH family	71
649660296	253	45.34	17	251	5	239	9.0e-63	233	COG3208	Surfactin synthase thioesterase subunit	244
649660298	2178	42.25	1333	1983	1	642	0.0e+00	487	COG1020	Non-ribosomal peptide synthetase component F	642
649660299	2623	46.67	1326	1977	1	642	0.0e+00	534	COG1020	Non-ribosomal peptide synthetase component F	642
649660300	2999	37.8	236	900	1	642	2.0e-123	438	COG1020	Non-ribosomal peptide synthetase component F	642
649660301	2392	39.76	1287	1947	1	642	9.0e-129	456	COG1020	Non-ribosomal peptide synthetase component F	642
649660302	1038	41.93	2	1011	1	1007	0.0e+00	917	COG0841	Multidrug efflux pump subunit AcrB	1009
649660303	359	30.45	14	352	9	366	1.0e-28	120	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
649660305	343	13.7	122	340	26	241	1.0e-05	44.4	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
649660306	124	34.15	1	119	9	130	7.0e-17	79.5	COG0848	Biopolymer transport protein ExbD	137
649660308	695	23.42	67	695	1	618	6.0e-66	245	COG1506	Dipeptidyl aminopeptidase/acylaminoacyl peptidase	620
649660309	154	32.46	27	139	14	126	3.0e-15	74.7	COG0662	Mannose-6-phosphate isomerase, cupin superfamily	127
649660312	855	28.45	177	855	64	750	1.0e-72	268	COG4774	Outer membrane receptor for monomeric catechols	750
649660313	310	39.54	1	304	24	321	2.0e-55	209	COG3712	Periplasmic ferric-dicitrate binding protein FerR, regulates iron transport through sigma-19	322
649660314	172	30	1	169	9	177	4.0e-28	117	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
649660315	149	33.09	4	141	3	141	1.0e-22	98.9	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
649660316	410	26.33	36	403	2	386	1.0e-36	147	COG3182	Uncharacterized iron-regulated membrane protein	442
649660317	864	27.62	149	864	41	753	6.0e-95	342	COG4772	Outer membrane receptor for Fe3+-dicitrate	753
649660318	339	38.7	20	339	15	321	3.0e-57	215	COG3712	Periplasmic ferric-dicitrate binding protein FerR, regulates iron transport through sigma-19	322
649660319	201	30.86	32	192	15	176	9.0e-24	103	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
649660321	857	26.38	132	856	23	750	7.0e-68	252	COG4774	Outer membrane receptor for monomeric catechols	750
649660323	329	38.6	1	329	1	320	3.0e-62	232	COG3712	Periplasmic ferric-dicitrate binding protein FerR, regulates iron transport through sigma-19	322
649660324	173	32.3	11	170	19	179	1.0e-22	99.4	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
649660326	105	36.73	1	98	25	122	7.0e-18	82.2	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
649660327	250	25.68	5	242	11	264	1.0e-07	50.3	COG0428	Zinc transporter ZupT	266
649660329	428	57.67	1	426	1	426	0.0e+00	553	COG0172	Seryl-tRNA synthetase	429
649660330	355	38.27	49	325	18	289	2.0e-58	220	COG1533	DNA repair photolyase	297
649660331	109	37.04	1	107	3	110	1.0e-16	78.4	COG0607	Rhodanese-related sulfurtransferase	110
649660332	356	36.56	56	328	4	275	2.0e-43	169	COG2006	Uncharacterized conserved protein, DUF362 family	293
649660333	185	25.9	18	181	9	168	9.0e-12	63.4	COG2825	Periplasmic chaperone for outer membrane proteins, Skp family	170
649660335	532	30.25	207	483	70	344	3.0e-46	179	COG2206	HD-GYP domain, c-di-GMP phosphodiesterase class II (or its inactivated variant)	344
649660337	223	27.06	1	207	2	210	4.0e-13	68.4	COG2755	Lysophospholipase L1 or related esterase	216
649660339	507	49.8	10	505	2	481	0.0e+00	653	COG0364	Glucose-6-phosphate 1-dehydrogenase	483
649660340	297	56.71	1	297	1	298	2.0e-113	401	COG1023	6-phosphogluconate dehydrogenase (decarboxylating)	300
649660343	350	45.22	8	348	1	341	2.0e-88	319	COG2008	Threonine aldolase	342
649660344	436	16.56	9	414	16	486	2.0e-37	150	COG3202	ATP/ADP translocase	509
649660345	454	39.77	9	437	4	417	6.0e-107	381	COG0014	Gamma-glutamyl phosphate reductase	417
649660349	391	20.8	13	333	16	366	1.0e-16	81.4	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
649660351	264	33.48	21	242	43	248	8.0e-44	170	COG2503	Predicted secreted acid phosphatase	274
649660353	484	38.42	52	463	47	463	6.0e-93	334	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
649660370	121	34.02	18	113	15	104	4.0e-11	60.4	COG3628	Phage baseplate assembly protein W	116
649660378	355	29.69	9	294	19	302	1.0e-30	127	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
649660382	296	23.45	7	296	3	248	2.0e-17	83.1	COG1801	Uncharacterized conserved protein YecE, DUF72 family	263
649660383	1033	32.56	2	995	1	1059	0.0e+00	712	COG0587	DNA polymerase III, alpha subunit	1139
649660384	394	25.64	3	346	1	345	2.0e-29	123	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
649660385	181	38.18	18	177	41	198	6.0e-26	110	COG1974	SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase)	201
649660389	129	45	8	127	5	123	6.0e-21	93	COG2363	Uncharacterized membrane protein YgdD, TMEM256/DUF423 family	124
649660391	263	34.72	55	262	21	236	3.0e-35	142	COG0412	Dienelactone hydrolase	236
649660392	329	29.46	8	323	3	338	2.0e-36	146	COG0673	Predicted dehydrogenase	342
649660395	509	54.14	14	506	1	490	0.0e+00	583	COG0606	Predicted ATPase with chaperone activity	490
649660398	864	56.63	5	863	1	786	0.0e+00	945	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
649660402	471	48.17	1	453	2	464	0.0e+00	499	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
649660413	394	11.69	27	333	2	298	4.0e-04	39.6	COG0582	Integrase	309
649660415	471	48.81	1	463	2	459	0.0e+00	509	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
649660416	693	19.72	202	411	40	243	4.0e-04	40.6	COG4105	Outer membrane protein assembly factor BamD, BamD/ComL family	254
649660418	472	45.69	14	470	1	464	0.0e+00	474	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
649660419	135	34.59	4	134	4	133	6.0e-24	103	COG1815	Flagellar basal body rod protein FlgB	133
649660420	149	49.66	1	149	1	137	3.0e-41	160	COG1558	Flagellar basal body rod protein FlgC	137
649660421	103	45.12	22	103	24	105	1.0e-13	68.4	COG1677	Flagellar hook-basal body complex protein FliE	105
649660422	518	37.85	4	517	15	545	2.0e-108	386	COG1766	Flagellar biosynthesis/type III secretory pathway M-ring protein FliF/YscJ	545
649660423	331	42.34	1	330	7	339	6.0e-70	257	COG1536	Flagellar motor switch protein FliG	339
649660425	435	54.99	2	432	11	440	0.0e+00	572	COG1157	Flagellar biosynthesis/type III secretory pathway ATPase	441
649660431	407	40.71	3	407	1	423	2.0e-78	286	COG1749	Flagellar hook protein FlgE	423
649660432	178	29.05	1	178	1	159	5.0e-20	90.7	COG1580	Flagellar basal body-associated protein FliL	159
649660433	323	38.08	1	323	1	320	2.0e-74	272	COG1868	Flagellar motor switch protein FliM	332
649660436	266	56.3	29	266	11	248	8.0e-78	283	COG1338	Flagellar biosynthetic protein FliP	248
649660437	89	47.73	1	88	1	88	1.0e-13	68.2	COG1987	Flagellar biosynthesis protein FliQ	89
649660438	263	34.12	7	261	4	258	1.0e-32	133	COG1684	Flagellar biosynthesis protein FliR	258
649660439	360	38.89	1	360	2	357	6.0e-96	344	COG1377	Flagellar biosynthesis protein FlhB	363
649660440	702	54.08	13	692	15	696	0.0e+00	807	COG1298	Flagellar biosynthesis pathway, component FlhA	696
649660441	427	30.37	1	398	1	397	4.0e-56	212	COG1419	Flagellar biosynthesis GTPase FlhF	407
649660442	288	36.29	23	277	1	251	8.0e-48	184	COG0455	MinD-like ATPase involved in chromosome partitioning or flagellar assembly	262
649660443	247	38.1	16	244	24	246	2.0e-46	178	COG1191	DNA-directed RNA polymerase specialized sigma subunit	247
649660444	291	36.31	113	268	19	174	5.0e-20	92.1	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
649660445	255	35.56	1	252	1	265	2.0e-48	186	COG4786	Flagellar basal body rod protein FlgG	265
649660446	263	54.31	1	263	1	265	2.0e-76	278	COG4786	Flagellar basal body rod protein FlgG	265
649660448	238	36.56	21	233	8	228	1.0e-44	173	COG2063	Flagellar basal body L-ring protein FlgH	230
649660449	436	46.49	67	436	6	365	1.0e-97	349	COG1706	Flagellar basal body P-ring protein FlgI	365
649660451	101	20.78	19	95	14	90	1.0e-02	31.8	COG2747	Negative regulator of flagellin synthesis (anti-sigma28 factor)	93
649660454	296	24.58	1	296	1	286	2.0e-19	90.1	COG1344	Flagellin and related hook-associated protein FlgL	360
649660455	81	52.54	1	59	1	59	2.0e-15	73.8	COG1551	sRNA-binding carbon storage regulator CsrA	73
649660456	158	28.47	4	139	3	138	1.0e-21	95.7	COG1699	Flagellar assembly factor FliW	146
649660457	950	33.12	188	506	22	326	1.0e-42	168	COG0642	Signal transduction histidine kinase	336
649660458	417	26.35	38	362	15	344	5.0e-39	155	COG2206	HD-GYP domain, c-di-GMP phosphodiesterase class II (or its inactivated variant)	344
649660460	397	27.74	11	396	3	370	1.0e-63	237	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
649660461	315	25.08	7	302	2	306	7.0e-39	154	COG0451	Nucleoside-diphosphate-sugar epimerase	314
649660462	356	37.98	1	326	1	333	2.0e-79	289	COG2605	Predicted kinase related to galactokinase and mevalonate kinase	333
649660464	378	30.05	2	370	12	392	1.0e-65	244	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
649660466	612	33.15	1	552	1	528	4.0e-109	389	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
649660467	541	24.54	28	442	30	452	3.0e-47	183	COG1032	Radical SAM superfamily enzyme YgiQ, UPF0313 family	490
649660468	1800	31.58	1264	1483	4	227	2.0e-39	159	COG1216	Glycosyltransferase, GT2 family	305
649660469	398	23.22	12	331	5	307	3.0e-28	119	COG0859	ADP-heptose:LPS heptosyltransferase	334
649660470	595	22.76	172	509	4	356	8.0e-20	92.7	COG4641	Spore maturation protein CgeB	373
649660471	558	24	3	350	2	322	5.0e-29	122	COG0859	ADP-heptose:LPS heptosyltransferase	334
649660473	275	31.46	3	269	1	265	1.0e-25	110	COG1344	Flagellin and related hook-associated protein FlgL	360
649660474	119	26.14	32	119	33	120	7.0e-10	56.1	COG1334	Uncharacterized conserved protein, FlaG/YvyC family	120
649660475	463	32.64	1	462	4	476	3.0e-48	186	COG1345	Flagellar capping protein FliD	483
649660476	130	40.8	1	125	2	126	1.0e-25	108	COG1516	Flagellin-specific chaperone FliS	132
649660479	315	28.62	1	289	1	240	2.0e-29	123	COG0455	MinD-like ATPase involved in chromosome partitioning or flagellar assembly	262
649660481	287	38.52	20	286	2	265	4.0e-58	218	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
649660483	216	23.39	10	215	2	217	1.0e-08	53.8	COG3143	Chemotaxis regulator CheZ, phosphatase of CheY~P	217
649660485	327	37.27	6	166	4	155	3.0e-29	122	COG0835	Chemotaxis signal transduction protein	165
649660486	365	50.71	15	365	2	343	3.0e-93	335	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
649660487	561	40.86	212	561	64	408	7.0e-54	205	COG0840	Methyl-accepting chemotaxis protein	408
649660488	172	43.62	18	166	4	152	6.0e-35	140	COG0835	Chemotaxis signal transduction protein	165
649660490	256	44.71	1	254	1	255	5.0e-66	244	COG1291	Flagellar motor component MotA	266
649660491	259	35.1	1	238	2	243	6.0e-47	180	COG1360	Flagellar motor protein MotB	244
649660495	715	40.3	9	714	2	716	0.0e+00	626	COG0643	Chemotaxis protein histidine kinase CheA	716
649660496	169	40.13	18	169	14	165	2.0e-36	145	COG0835	Chemotaxis signal transduction protein	165
649660497	772	39.94	406	703	84	406	1.0e-56	215	COG0840	Methyl-accepting chemotaxis protein	408
649660498	153	25.74	16	151	54	177	1.0e-06	46	COG2322	Uncharacterized membrane protein YozB, DUF420 family	177
649660499	272	42.12	7	272	1	267	2.0e-71	262	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
649660500	205	38.12	16	172	1	157	8.0e-38	150	COG1871	Chemotaxis receptor (MCP) glutamine deamidase CheD	164
649660501	349	53.6	3	348	1	345	2.0e-109	389	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
649660502	112	29.79	9	101	12	105	2.0e-08	50.8	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
649660503	116	27.18	12	113	15	117	2.0e-07	48.1	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
649660504	421	28.09	147	410	102	365	2.0e-38	153	COG2208	Serine phosphatase RsbU, regulator of sigma subunit	367
649660505	119	34.48	6	92	8	94	2.0e-04	38.2	COG2198	HPt (histidine-containing phosphotransfer) domain	122
649660508	73	44.78	1	67	1	66	4.0e-12	63	COG1724	Predicted RNA binding protein YcfA, dsRBD-like fold, HicA-like mRNA interferase family	66
649660510	366	39.47	1	362	3	371	9.0e-87	314	COG0381	UDP-N-acetylglucosamine 2-epimerase	383
649660512	96	52.75	1	88	2	92	1.0e-18	84.6	COG2929	Uncharacterized conserved protein, DUF497 family	93
649660515	84	53.57	1	84	1	84	3.0e-26	110	COG4115	Toxin component of the Txe-Axe toxin-antitoxin module, Txe/YoeB family	84
649660516	83	36.59	1	80	3	84	2.0e-11	60.8	COG2161	Antitoxin component YafN of the YafNO toxin-antitoxin module, PHD/YefM family	86
649660522	471	20.05	11	427	12	400	3.0e-03	37	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
649660526	383	27.2	19	381	11	380	7.0e-32	131	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649660527	411	25.79	9	385	1	375	1.0e-30	127	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649660528	373	25.36	14	350	11	333	5.0e-31	129	COG0859	ADP-heptose:LPS heptosyltransferase	334
649660529	150	37.93	8	150	41	184	2.0e-29	121	COG1045	Serine acetyltransferase	194
649660530	602	24.05	125	591	92	565	2.0e-28	121	COG5360	Uncharacterized conserved protein, heparinase superfamily	566
649660531	416	24.46	1	408	1	381	4.0e-22	99.3	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649660535	542	30.87	7	305	7	312	6.0e-37	149	COG0472	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase	319
649660539	589	19.35	3	518	1	458	2.0e-25	110	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
649660541	743	27.41	418	743	2	340	3.0e-38	153	COG0673	Predicted dehydrogenase	342
649660542	474	31.8	1	260	9	269	2.0e-33	137	COG3267	Type II secretory pathway, component ExeA (predicted ATPase)	269
649660543	240	36.89	6	226	3	225	2.0e-35	143	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
649660545	165	27.67	1	158	2	157	2.0e-13	68.8	COG2062	Phosphohistidine phosphatase SixA	163
649660546	517	36.3	1	458	2	446	4.0e-94	339	COG0248	Exopolyphosphatase/pppGpp-phosphohydrolase	492
649660547	222	41.74	1	217	9	226	1.0e-43	169	COG0704	Phosphate uptake regulator	240
649660548	286	70.75	34	286	2	253	3.0e-128	451	COG1117	ABC-type phosphate transport system, ATPase component	253
649660549	549	40.07	274	544	46	292	6.0e-61	228	COG0581	ABC-type phosphate transport system, permease component	292
649660550	742	38.66	16	739	15	730	0.0e+00	521	COG4590	ABC-type uncharacterized transport system, permease component	733
649660551	338	32.44	40	325	26	313	7.0e-48	184	COG0226	ABC-type phosphate transport system, periplasmic component	318
649660553	177	19.31	6	149	10	148	9.0e-07	46.9	COG3065	Starvation-inducible outer membrane lipoprotein	191
649660556	371	26.78	15	352	8	318	7.0e-34	138	COG0226	ABC-type phosphate transport system, periplasmic component	318
649660557	234	36.4	8	231	5	229	1.0e-38	153	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
649660559	169	26.92	24	149	5	133	2.0e-03	35.9	COG3431	Uncharacterized membrane protein, DUF373 family	142
649660561	385	26.89	11	354	3	316	6.0e-30	125	COG0226	ABC-type phosphate transport system, periplasmic component	318
649660562	375	26.35	14	353	6	317	3.0e-31	129	COG0226	ABC-type phosphate transport system, periplasmic component	318
649660566	500	18.16	136	497	52	426	2.0e-03	37.7	COG3746	Phosphate-selective porin	426
649660568	229	35.65	8	229	3	228	4.0e-38	151	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
649660570	192	31.67	12	191	12	188	1.0e-27	116	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
649660571	1236	50.22	4	688	1	663	0.0e+00	761	COG1331	Uncharacterized conserved protein YyaL, SSP411 family, contains thoiredoxin and six-hairpin glycosidase-like domains	667
649660573	480	51.03	96	480	30	416	3.0e-129	455	COG0281	Malic enzyme	432
649660574	437	17.07	143	437	96	423	5.0e-05	42.9	COG1055	Na+/H+ antiporter NhaD or related arsenite permease	424
649660576	401	40.27	11	380	1	361	6.0e-82	298	COG0349	Ribonuclease D	361
649660578	116	32.11	4	112	3	111	3.0e-24	103	COG1393	Arsenate reductase and related proteins, glutaredoxin family	117
649660582	377	49.87	5	377	16	390	1.0e-118	420	COG0372	Citrate synthase	390
649660584	151	39.04	7	151	1	146	5.0e-25	107	COG0071	Molecular chaperone IbpA, HSP20 family	146
649660585	484	59.96	16	476	1	462	0.0e+00	669	COG0114	Fumarate hydratase class II	462
649660586	456	23.21	9	391	122	457	3.0e-26	113	COG0493	NADPH-dependent glutamate synthase beta chain or related oxidoreductase	457
649660587	286	39.44	4	285	1	281	1.0e-65	242	COG0061	NAD kinase	281
649660588	809	51.43	4	805	1	786	0.0e+00	908	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
649660589	346	51.68	1	324	1	324	1.0e-105	376	COG0533	tRNA A37 threonylcarbamoyltransferase TsaD	342
649660590	538	52.51	162	517	4	360	6.0e-106	378	COG2262	50S ribosomal subunit-associated GTPase HflX	411
649660591	223	50.72	16	222	4	210	4.0e-69	254	COG0177	Endonuclease III	211
649660592	292	39.04	1	292	1	290	3.0e-67	248	COG1561	Uncharacterized conserved protein YicC, UPF0701 family	290
649660593	219	50.55	1	182	6	186	2.0e-60	225	COG0194	Guanylate kinase	191
649660595	419	51.52	7	400	1	390	2.0e-109	389	COG0452	Phosphopantothenoylcysteine synthetase/decarboxylase	392
649660597	165	58.74	3	145	2	144	2.0e-56	211	COG0757	3-dehydroquinate dehydratase	146
649660598	186	46.51	1	129	3	131	4.0e-35	141	COG0231	Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)	131
649660599	191	38.78	43	187	1	140	4.0e-26	111	COG0511	Biotin carboxyl carrier protein	140
649660601	204	50	3	194	14	204	3.0e-49	188	COG0352	Thiamine monophosphate synthase	211
649660602	254	41.33	1	225	1	219	2.0e-49	188	COG0132	Dethiobiotin synthetase	223
649660604	251	35.86	13	251	4	251	2.0e-37	149	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
649660606	993	37.07	525	987	18	472	1.0e-109	392	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
649660611	277	35.79	11	272	11	277	3.0e-52	198	COG1398	Fatty-acid desaturase	289
649660612	295	46.93	17	239	49	265	8.0e-57	214	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
649660613	101	40.38	1	101	2	105	9.0e-20	88.5	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
649660624	420	28.71	124	420	3	279	3.0e-35	143	COG1355	Predicted class III extradiol dioxygenase, MEMO1 family	279
649660628	196	41.82	34	191	1	152	5.0e-36	144	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
649660631	103	20.41	5	99	15	111	8.0e-03	32.2	COG2337	mRNA-degrading endonuclease, toxin component of the MazEF toxin-antitoxin module	112
649660633	658	27.36	9	538	3	489	5.0e-53	202	COG0286	Type I restriction-modification system, DNA methylase subunit	489
649660634	444	16.87	16	422	1	380	7.0e-23	102	COG0732	Restriction endonuclease S subunit	391
649660635	116	28	21	115	17	113	7.0e-03	32.6	COG4679	Phage-related protein	116
649660637	977	21.96	116	845	104	793	7.0e-64	239	COG0610	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases ...	962
649660638	220	41.52	3	220	1	224	8.0e-49	187	COG2003	DNA repair protein RadC, contains a helix-hairpin-helix DNA-binding motif	224
649660640	107	37.5	1	107	1	112	7.0e-16	75.8	COG2337	mRNA-degrading endonuclease, toxin component of the MazEF toxin-antitoxin module	112
649660641	84	20.34	1	58	1	59	9.0e-06	41.8	COG2336	Antitoxin component of the MazEF toxin-antitoxin module	82
649660643	114	31.58	1	113	2	112	2.0e-10	57.7	COG2337	mRNA-degrading endonuclease, toxin component of the MazEF toxin-antitoxin module	112
649660645	414	22.54	10	401	26	428	2.0e-22	100	COG2271	Sugar phosphate permease	448
649660647	385	28.95	24	380	33	378	2.0e-45	176	COG0006	Xaa-Pro aminopeptidase	384
649660648	324	45.49	1	243	1	234	7.0e-66	244	COG0479	Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit	234
649660649	146	33.83	14	146	10	137	2.0e-12	64.9	COG1371	SHS2 domain protein implicated in nucleic acid metabolism	137
649660650	483	46.52	24	483	1	432	0.0e+00	502	COG1690	RNA-splicing ligase RtcB, repairs tRNA damage	432
649660655	472	36.78	6	455	5	454	6.0e-115	408	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
649660656	296	23.93	22	293	6	283	4.0e-28	118	COG1639	HD-like signal output (HDOD) domain, no enzymatic activity	289
649660658	300	41.03	3	291	1	290	5.0e-78	284	COG2048	Heterodisulfide reductase, subunit B	293
649660661	343	18.62	23	309	11	266	7.0e-13	68.5	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
649660665	222	30.19	1	212	2	212	7.0e-34	137	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
649660666	628	29	24	624	13	663	1.0e-110	394	COG0021	Transketolase	663
649660668	194	58.76	18	193	1	177	8.0e-58	216	COG2065	Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase	179
649660669	306	52.23	1	305	3	313	9.0e-105	373	COG0540	Aspartate carbamoyltransferase, catalytic chain	316
649660670	430	48.46	1	422	1	421	0.0e+00	468	COG0044	Dihydroorotase or related cyclic amidohydrolase	430
649660672	394	55.19	1	393	1	366	0.0e+00	533	COG0505	Carbamoylphosphate synthase small subunit	368
649660673	358	39.03	75	343	52	310	2.0e-54	206	COG0616	Periplasmic serine protease, ClpP class	317
649660675	1089	70.13	13	407	1	393	0.0e+00	566	COG0458	Carbamoylphosphate synthase large subunit	400
649660676	158	48.68	5	156	1	151	1.0e-33	136	COG0782	Transcription elongation factor, GreA/GreB family	151
649660677	263	39.7	1	263	1	266	9.0e-69	253	COG1912	S-adenosylmethionine hydrolase (SAM-hydroxide adenosyltransferase)	268
649660678	382	23.1	10	375	14	364	6.0e-22	98.7	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
649660680	455	45.81	1	449	1	446	0.0e+00	527	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
649660681	603	65.84	1	603	1	603	0.0e+00	1018	COG0481	Translation elongation factor EF-4, membrane-bound GTPase	603
649660682	259	31.14	43	170	4	166	2.0e-16	79.3	COG0681	Signal peptidase I	166
649660684	263	45.2	11	256	3	247	2.0e-65	242	COG1212	CMP-2-keto-3-deoxyoctulosonic acid synthetase	247
649660685	540	65.6	10	537	2	530	0.0e+00	879	COG0504	CTP synthase (UTP-ammonia lyase)	533
649660686	273	61.17	1	273	1	272	4.0e-117	414	COG2877	3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase	279
649660687	345	57.14	33	227	6	201	7.0e-64	237	COG0794	D-arabinose 5-phosphate isomerase GutQ	202
649660688	204	41.3	23	203	13	192	1.0e-20	93.2	COG0558	Phosphatidylglycerophosphate synthase	192
649660689	200	41.62	6	197	4	200	3.0e-38	151	COG0344	Phospholipid biosynthesis protein PlsY, probable glycerol-3-phosphate acyltransferase	200
649660691	468	46.77	55	359	35	342	1.0e-69	257	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
649660692	701	42.03	6	692	7	692	0.0e+00	656	COG0480	Translation elongation factor EF-G, a GTPase	697
649660693	238	49.55	10	231	3	224	2.0e-66	245	COG2003	DNA repair protein RadC, contains a helix-hairpin-helix DNA-binding motif	224
649660695	190	41.99	1	178	2	181	5.0e-48	183	COG0742	16S rRNA G966 N2-methylase RsmD	187
649660696	162	59.62	1	156	2	157	7.0e-60	223	COG0669	Phosphopantetheine adenylyltransferase	159
649660697	397	43.18	6	397	2	393	3.0e-104	371	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
649660698	134	43.84	1	72	8	80	7.0e-13	66.6	COG2331	Predicted nucleic acid-binding protein, contains Zn-ribbon domain	82
649660701	215	41.5	13	209	13	211	4.0e-41	161	COG0009	tRNA A37 threonylcarbamoyladenosine synthetase subunit TsaC/SUA5/YrdC	211
649660702	425	54.21	1	425	1	427	0.0e+00	542	COG0151	Phosphoribosylamine-glycine ligase	428
649660703	517	59.23	4	517	2	515	0.0e+00	719	COG0138	AICAR transformylase/IMP cyclohydrolase PurH	515
649660704	301	30.81	118	298	4	188	1.0e-23	104	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
649660706	394	40.66	3	394	2	394	5.0e-59	222	COG3213	Uncharacterized protein involved in response to NO	396
649660710	1150	51.56	3	1113	2	1110	0.0e+00	1287	COG0587	DNA polymerase III, alpha subunit	1139
649660711	322	65.29	1	313	1	314	0.0e+00	464	COG0825	Acetyl-CoA carboxylase alpha subunit	317
649660715	832	38.4	3	831	48	844	0.0e+00	682	COG1643	HrpA-like RNA helicase	845
649660716	182	27.27	1	173	2	171	2.0e-17	82.2	COG2716	Glycine cleavage system regulatory protein	176
649660717	163	41.1	1	162	1	162	5.0e-43	166	COG0242	Peptide deformylase	168
649660719	420	24.28	6	420	1	481	9.0e-26	111	COG1233	Phytoene dehydrogenase-related protein	487
649660722	255	42.74	1	226	3	236	3.0e-57	215	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
649660726	300	26.24	47	298	3	282	1.0e-24	107	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
649660732	114	18.81	1	101	1	97	5.0e-05	40	COG1694	NTP pyrophosphatase, house-cleaning of non-canonical NTPs	102
649660735	278	24.29	1	139	1	136	2.0e-11	63	COG1943	REP element-mobilizing transposase RayT	136
649660736	340	33.92	4	340	10	339	2.0e-49	190	COG1294	Cytochrome bd-type quinol oxidase, subunit 2	346
649660737	447	41.44	1	439	1	442	1.0e-100	360	COG1271	Cytochrome bd-type quinol oxidase, subunit 1	457
649660740	463	40	6	462	3	411	2.0e-93	336	COG2262	50S ribosomal subunit-associated GTPase HflX	411
649660741	105	24.32	28	100	21	93	8.0e-03	32.2	COG3549	Plasmid maintenance system killer protein	94
649660742	89	40	22	71	6	55	3.0e-05	40.2	COG1476	DNA-binding transcriptional regulator, XRE-family HTH domain	68
649660746	164	22.64	1	155	4	161	3.0e-08	51.6	COG2453	Protein-tyrosine phosphatase	180
649660750	360	52.74	10	337	2	322	6.0e-103	367	COG3943	Uncharacterized conserved protein	329
649660751	404	19.12	5	403	1	391	7.0e-21	95.5	COG0732	Restriction endonuclease S subunit	391
649660752	484	23.91	7	484	12	485	8.0e-47	181	COG0286	Type I restriction-modification system, DNA methylase subunit	489
649660754	110	37.5	1	110	6	115	2.0e-13	68	COG4679	Phage-related protein	116
649660756	687	29.15	389	674	55	327	9.0e-29	122	COG0642	Signal transduction histidine kinase	336
649660758	257	18.62	35	207	37	217	1.0e-04	40.6	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
649660762	329	29.69	5	324	5	305	2.0e-34	140	COG2378	Predicted DNA-binding transcriptional regulator YafY, contains an HTH and WYL domains	311
649660765	946	33.01	16	514	2	453	1.0e-77	284	COG0277	FAD/FMN-containing dehydrogenase	459
649660766	323	43.65	4	321	3	324	2.0e-92	332	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
649660767	639	23.53	110	346	32	229	5.0e-06	46.5	COG3063	Tfp pilus assembly protein PilF	250
649660768	72	65.62	2	64	1	64	3.0e-21	93.3	COG1278	Cold shock protein, CspA family	67
649660769	361	25.55	5	361	3	364	3.0e-38	152	COG0795	Lipopolysaccharide export LptBFGC system, permease protein LptF	364
649660770	363	27.6	1	363	1	363	8.0e-42	164	COG0795	Lipopolysaccharide export LptBFGC system, permease protein LptF	364
649660771	418	48.67	1	414	1	409	3.0e-114	405	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
649660772	113	30.77	4	81	3	80	4.0e-11	60.3	COG0236	Acyl carrier protein	80
649660773	360	44.08	7	341	1	338	6.0e-87	314	COG1044	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase	338
649660781	1129	32.91	335	968	3	706	1.0e-125	444	COG0643	Chemotaxis protein histidine kinase CheA	716
649660782	624	33.42	239	623	26	408	7.0e-39	155	COG0840	Methyl-accepting chemotaxis protein	408
649660783	145	32.35	3	137	22	157	2.0e-21	94.6	COG0835	Chemotaxis signal transduction protein	165
649660786	523	47.67	7	519	1	486	0.0e+00	528	COG1492	Cobyric acid synthase	486
649660787	242	32.09	20	232	8	194	1.0e-26	113	COG1865	Adenosylcobinamide amidohydrolase	200
649660788	369	37.23	4	368	6	356	1.0e-67	250	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
649660789	318	45.13	6	313	9	311	1.0e-75	276	COG1270	Cobalamin biosynthesis protein CobD/CbiB	320
649660790	254	33.47	4	247	1	239	1.0e-23	103	COG0368	Cobalamin synthase	246
649660791	350	45.87	1	350	1	337	2.0e-75	276	COG2038	NaMN:DMB phosphoribosyltransferase	347
649660792	177	49.13	10	177	2	174	1.0e-44	172	COG2087	Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase	175
649660793	198	47.92	2	193	3	182	9.0e-52	196	COG2096	Cob(I)alamin adenosyltransferase	184
649660794	250	30.99	16	221	1	207	5.0e-25	108	COG0778	Nitroreductase	207
649660796	199	57.58	2	199	1	198	5.0e-72	263	COG2109	ATP:corrinoid adenosyltransferase	198
649660797	465	51.77	4	453	1	451	0.0e+00	525	COG1797	Cobyrinic acid a,c-diamide synthase	451
649660798	660	27.92	39	656	22	608	2.0e-77	284	COG4206	Outer membrane cobalamin receptor protein	608
649660799	298	43.77	23	287	1	253	4.0e-75	274	COG1120	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	258
649660800	386	39.41	47	384	3	332	7.0e-55	208	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
649660801	340	33.22	57	332	31	318	6.0e-40	158	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
649660803	85	43.21	4	84	5	85	2.0e-12	63.7	COG4095	Uncharacterized conserved protein, contains PQ loop repeat	89
649660804	63	50	1	56	1	58	2.0e-12	63.8	COG0227	Ribosomal protein L28	77
649660807	630	32.86	10	200	18	226	8.0e-23	102	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
649660808	777	33.33	10	201	22	227	1.0e-21	99	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
649660810	680	42.43	14	611	1	581	0.0e+00	560	COG1086	NDP-sugar epimerase, includes UDP-GlcNAc-inverting 4,6-dehydratase FlaA1 and capsular polysaccharide biosynthesis protein EpsC	588
649660811	215	21.78	2	186	11	209	2.0e-04	39.8	COG1434	Uncharacterized SAM-binding protein YcdF, DUF218 family	223
649660812	372	36.12	5	371	7	371	4.0e-85	308	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
649660813	159	25.68	1	147	4	150	8.0e-21	93.1	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
649660819	521	28.14	2	521	19	530	1.0e-65	244	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
649660820	340	24.17	16	327	3	321	3.0e-26	113	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
649660821	214	48.37	18	197	41	224	5.0e-56	210	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
649660824	412	26.5	48	386	48	381	3.0e-28	119	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649660827	386	26.98	10	375	14	380	1.0e-37	150	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649660830	374	27.6	1	365	3	377	1.0e-33	137	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649660831	374	27.68	8	371	1	375	3.0e-36	146	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649660836	374	22.22	5	365	13	381	5.0e-16	79.1	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
649660837	459	29.82	16	447	1	436	2.0e-53	203	COG0728	Peptidoglycan biosynthesis protein MviN/MurJ, putative lipid II flippase	518
649660838	731	27.79	2	475	1	454	6.0e-56	212	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
649660839	481	18.21	102	477	98	464	2.0e-07	50.8	COG5338	Uncharacterized protein	468
649660841	187	22.86	25	183	5	178	1.0e-10	59.9	COG0250	Transcription antitermination factor NusG	178
649660843	235	30.73	13	229	3	209	1.0e-31	129	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
649660845	445	26.35	42	441	43	445	8.0e-32	131	COG1538	Outer membrane protein TolC	457
649660849	638	44.1	27	625	24	604	0.0e+00	502	COG0653	Preprotein translocase subunit SecA (ATPase, RNA helicase)	822
649660851	488	20.39	227	415	24	275	2.0e-10	61.1	COG1566	Multidrug resistance efflux pump	352
649660853	405	43.17	1	404	1	401	7.0e-107	381	COG0162	Tyrosyl-tRNA synthetase	401
649660855	473	45.85	4	456	7	453	5.0e-127	448	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
649660856	128	50	2	125	5	130	3.0e-38	150	COG0509	Glycine cleavage system H protein (lipoate-binding)	131
649660858	139	51.49	1	134	1	134	1.0e-48	185	COG0105	Nucleoside diphosphate kinase	135
649660859	343	59.64	4	338	5	338	5.0e-129	454	COG0182	Methylthioribose-1-phosphate isomerase (methionine salvage pathway), a paralog of eIF-2B alpha subunit	346
649660860	355	41.48	4	352	6	369	4.0e-82	298	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
649660861	393	21.09	1	389	1	381	7.0e-17	82	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649660862	843	30.04	535	817	34	292	4.0e-43	170	COG2333	Metal-dependent hydrolase, beta-lactamase superfamily II	293
649660863	449	47.19	1	449	6	462	2.0e-121	429	COG1109	Phosphomannomutase	464
649660864	296	46.38	18	291	1	271	8.0e-76	277	COG0294	Dihydropteroate synthase	274
649660865	604	59.7	9	598	1	593	0.0e+00	739	COG0465	ATP-dependent Zn proteases	596
649660866	183	53.01	9	174	11	176	1.0e-58	219	COG0634	Hypoxanthine-guanine phosphoribosyltransferase	178
649660867	461	39.39	2	254	27	286	5.0e-43	168	COG0037	tRNA(Ile)-lysidine synthase TilS/MesJ	298
649660868	321	41.04	1	306	1	304	2.0e-77	282	COG0196	FAD synthase	304
649660869	327	66.46	1	325	3	330	0.0e+00	517	COG0113	Delta-aminolevulinic acid dehydratase, porphobilinogen synthase	330
649660871	521	57.09	4	250	2	244	3.0e-83	302	COG0007	Uroporphyrinogen-III methylase (siroheme synthase)	244
649660872	310	56.91	5	307	3	306	2.0e-107	382	COG0181	Porphobilinogen deaminase	307
649660873	468	45.86	1	423	1	414	1.0e-114	407	COG0373	Glutamyl-tRNA reductase	414
649660874	268	23.26	1	258	1	254	3.0e-13	69.1	COG4137	ABC-type uncharacterized transport system, permease component	265
649660875	250	38.39	16	238	3	226	3.0e-44	172	COG0313	16S rRNA C1402 (ribose-2'-O) methylase RsmI	275
649660876	86	36	11	84	4	78	7.0e-14	68.7	COG0425	TusA-related sulfurtransferase	78
649660879	93	27.14	4	73	5	74	2.0e-06	43.8	COG2924	Fe-S cluster biosynthesis and repair protein YggX	90
649660880	151	40.67	1	142	2	151	6.0e-31	126	COG1259	Bifunctional DNase/RNase	151
649660881	162	39.06	11	137	1	128	5.0e-25	107	COG1259	Bifunctional DNase/RNase	151
649660882	143	57.34	2	143	1	143	6.0e-49	186	COG0102	Ribosomal protein L13	148
649660883	130	54.62	1	130	1	130	3.0e-38	150	COG0103	Ribosomal protein S9	130
649660884	357	53.22	4	357	3	349	1.0e-121	430	COG0002	N-acetyl-gamma-glutamylphosphate reductase	349
649660885	403	52.48	1	403	5	404	0.0e+00	472	COG1364	N-acetylglutamate synthase (N-acetylornithine aminotransferase)	404
649660886	257	55.93	1	236	1	235	2.0e-90	325	COG0052	Ribosomal protein S2	252
649660888	241	63.09	6	237	5	237	2.0e-85	309	COG0528	Uridylate kinase	238
649660889	187	54.55	1	187	1	187	6.0e-61	226	COG0233	Ribosome recycling factor	187
649660890	387	43.36	8	374	3	359	5.0e-106	378	COG0787	Alanine racemase	360
649660892	102	47.47	1	97	2	100	2.0e-22	97.2	COG0011	Uncharacterized conserved protein YqgV, UPF0045/DUF77 family	100
649660893	217	34.43	7	189	4	185	1.0e-29	123	COG1648	Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain)	210
649660895	181	31.13	11	161	1	144	5.0e-16	77.3	COG1403	5-methylcytosine-specific restriction endonuclease McrA	146
649660896	108	37.5	5	105	3	106	8.0e-18	81.9	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
649660900	108	42.59	48	101	1	54	1.0e-12	64.6	COG3411	(2Fe-2S) ferredoxin	64
649660901	170	42.77	12	168	3	160	7.0e-44	170	COG0521	Molybdopterin biosynthesis enzyme MoaB	169
649660904	343	44	1	342	1	326	2.0e-80	292	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
649660905	309	45.07	4	307	1	289	4.0e-72	265	COG0384	Predicted epimerase YddE/YHI9, PhzF superfamily	291
649660908	653	19.9	208	602	68	466	2.0e-26	114	COG1032	Radical SAM superfamily enzyme YgiQ, UPF0313 family	490
649660921	116	35.16	24	114	24	114	3.0e-12	63.9	COG0599	Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family	124
649660924	328	39.47	209	322	11	124	2.0e-20	93.8	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
649660925	315	19.92	111	312	56	289	5.0e-05	42.3	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
649660927	228	28.49	39	223	12	173	2.0e-25	109	COG0663	Carbonic anhydrase or acetyltransferase, isoleucine patch superfamily	176
649660928	148	31.08	4	144	8	149	6.0e-17	80.1	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
649660931	300	24.41	4	300	1	297	1.0e-23	103	COG0583	DNA-binding transcriptional regulator, LysR family	297
649660933	486	22.41	11	474	1	389	4.0e-13	69.8	COG2814	Predicted arabinose efflux permease, MFS family	394
649660935	478	45.3	1	448	4	459	1.0e-127	450	COG0469	Pyruvate kinase	477
649660936	191	33.75	7	166	19	177	8.0e-24	103	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
649660937	153	24.79	4	113	7	126	2.0e-04	38.8	COG3565	Predicted dioxygenase of extradiol dioxygenase family	138
649660938	184	28.95	5	154	4	136	8.0e-15	73.4	COG0262	Dihydrofolate reductase	167
649660941	144	43.75	16	143	9	136	4.0e-33	133	COG3011	Predicted thiol-disulfide oxidoreductase YuxK, DCC family	137
649660942	147	34.69	51	147	16	108	2.0e-14	71.5	COG0607	Rhodanese-related sulfurtransferase	110
649660944	394	27.19	117	333	4	218	9.0e-27	115	COG1639	HD-like signal output (HDOD) domain, no enzymatic activity	289
649660945	132	38.81	1	127	16	149	8.0e-16	76.2	COG2165	Type II secretory pathway, pseudopilin PulG	149
649660947	437	56.63	24	437	3	417	0.0e+00	566	COG0014	Gamma-glutamyl phosphate reductase	417
649660948	209	20.16	20	147	4	128	2.0e-03	36.6	COG2165	Type II secretory pathway, pseudopilin PulG	149
649660952	335	18.95	30	304	31	316	8.0e-07	48.4	COG4972	Tfp pilus assembly protein, ATPase PilM	354
649660953	577	45.95	84	573	20	499	0.0e+00	500	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
649660954	404	35.4	1	404	1	397	5.0e-83	301	COG1459	Type II secretory pathway, component PulF	397
649660955	279	29.52	157	261	10	112	1.0e-06	47.5	COG1388	LysM repeat	124
649660957	168	28.57	2	126	6	126	1.0e-08	53.1	COG2165	Type II secretory pathway, pseudopilin PulG	149
649660959	431	38.75	2	423	5	429	2.0e-119	422	COG0677	UDP-N-acetyl-D-mannosaminuronate dehydrogenase	436
649660960	398	23.45	1	363	7	373	3.0e-21	96.8	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
649660961	342	26.62	4	142	22	156	3.0e-13	70.1	COG3666	Transposase	161
649660964	263	49.6	1	249	2	253	2.0e-57	215	COG1484	DNA replication protein DnaC	254
649660965	412	31.8	1	278	8	275	6.0e-24	105	COG4584	Transposase	278
649660977	348	15.47	61	327	86	359	4.0e-10	59.3	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649660978	410	23.55	94	406	61	381	9.0e-18	85.1	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649660979	383	31.25	11	383	3	380	4.0e-39	155	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649660980	374	30.39	10	373	5	381	8.0e-42	164	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649660982	442	18.61	12	352	15	373	4.0e-07	49.8	COG3307	O-antigen ligase	424
649660983	350	18.4	214	334	9	132	6.0e-05	42	COG3335	Transposase	132
649660985	176	30.34	22	166	1	135	6.0e-24	103	COG0394	Protein-tyrosine-phosphatase	139
649660986	399	21.88	12	397	10	385	4.0e-20	92.8	COG3919	Predicted ATP-dependent carboligase, ATP-grasp superfamily	415
649660990	379	22.66	6	374	15	388	4.0e-17	83.1	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
649660991	425	23.26	31	397	34	370	6.0e-37	148	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
649660994	631	30.38	1	597	1	518	5.0e-94	338	COG0367	Asparagine synthetase B (glutamine-hydrolyzing)	542
649660995	336	35.94	1	332	1	310	1.0e-49	190	COG0451	Nucleoside-diphosphate-sugar epimerase	314
649660996	614	47.42	1	597	1	555	0.0e+00	666	COG2192	Predicted carbamoyl transferase, NodU family	555
649660997	387	28.61	1	387	1	381	3.0e-42	166	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649660998	302	26.02	1	265	2	256	2.0e-25	109	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
649660999	412	21.84	1	410	1	381	2.0e-25	110	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649661000	356	27.4	2	351	1	314	6.0e-36	145	COG0451	Nucleoside-diphosphate-sugar epimerase	314
649661007	309	29.94	11	303	2	311	2.0e-34	140	COG0451	Nucleoside-diphosphate-sugar epimerase	314
649661009	420	52.76	1	417	18	433	0.0e+00	565	COG4310	Uncharacterized protein, cotains an aminopeptidase-like domain	435
649661011	448	45.24	2	428	7	413	2.0e-122	433	COG1004	UDP-glucose 6-dehydrogenase	414
649661012	377	30.84	36	364	1	311	8.0e-40	158	COG0451	Nucleoside-diphosphate-sugar epimerase	314
649661014	423	45.02	3	251	1	239	5.0e-78	285	COG1134	ABC-type polysaccharide/polyol phosphate transport system, ATPase component	249
649661015	281	35.94	26	281	10	263	1.0e-44	173	COG1682	ABC-type polysaccharide/polyol phosphate export permease	263
649661018	355	47.92	164	354	38	225	9.0e-59	220	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
649661019	784	19.18	6	476	12	458	2.0e-28	121	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
649661022	233	36.11	56	230	38	211	1.0e-28	120	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
649661026	544	31.36	12	295	9	289	5.0e-63	235	COG2513	2-Methylisocitrate lyase and related enzymes, PEP mutase family	289
649661029	496	45.31	2	488	6	479	0.0e+00	490	COG0297	Glycogen synthase	487
649661032	252	26.75	3	244	5	241	6.0e-32	131	COG1381	Recombinational DNA repair protein (RecF pathway)	251
649661033	445	40.23	6	442	12	448	1.0e-95	343	COG2239	Mg/Co/Ni transporter MgtE (contains CBS domain)	451
649661034	294	52.36	1	294	4	295	6.0e-96	344	COG1159	GTPase Era, involved in 16S rRNA processing	298
649661036	428	69.5	1	423	1	419	0.0e+00	642	COG0148	Enolase	423
649661038	476	57.74	1	475	4	481	0.0e+00	694	COG0064	Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit	483
649661039	106	21.98	8	98	3	93	5.0e-06	43	COG4980	Gas vesicle protein	115
649661040	133	25.71	2	106	3	107	1.0e-07	49.2	COG4768	Uncharacterized protein YoxC, contains an MCP-like domain	139
649661041	491	56.01	6	488	4	474	0.0e+00	517	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
649661042	121	58.12	2	118	1	117	4.0e-41	159	COG0853	Aspartate 1-decarboxylase	126
649661043	97	51.04	1	96	1	96	4.0e-21	93	COG0721	Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit	96
649661044	610	52.54	1	610	1	597	0.0e+00	804	COG0449	Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains	597
649661045	539	51.5	19	484	5	457	0.0e+00	580	COG1207	Bifunctional protein GlmU, N-acetylglucosamine-1-phosphate-uridyltransferase/glucosamine-1-phosphate-acetyltransferase	460
649661046	241	39.9	19	217	2	204	4.0e-46	178	COG2928	Uncharacterized membrane protein	222
649661047	241	44.66	10	214	2	206	1.0e-59	222	COG0125	Thymidylate kinase	208
649661049	663	42.63	1	515	1	547	0.0e+00	569	COG0143	Methionyl-tRNA synthetase	558
649661051	594	54.99	16	590	1	587	0.0e+00	658	COG0465	ATP-dependent Zn proteases	596
649661052	325	43.17	22	299	21	296	8.0e-62	230	COG1230	Co/Zn/Cd efflux system component	296
649661054	315	28.83	3	314	1	322	1.0e-39	157	COG0523	GTPase, G3E family	323
649661056	80	33.33	2	62	3	62	2.0e-03	34.1	COG1724	Predicted RNA binding protein YcfA, dsRBD-like fold, HicA-like mRNA interferase family	66
649661061	598	21	37	301	46	315	7.0e-05	42.9	COG1520	Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat	370
649661062	236	32.14	165	220	1	55	3.0e-06	45.7	COG3422	Uncharacterized conserved protein YegP, UPF0339 family	59
649661072	752	22.95	138	557	59	417	1.0e-23	105	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
649661080	384	33.24	21	368	1	346	8.0e-52	198	COG3177	Fic family protein	348
649661082	163	30.83	41	160	7	126	1.0e-12	66.1	COG1846	DNA-binding transcriptional regulator, MarR family	126
649661083	389	32.04	1	358	5	357	2.0e-30	126	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
649661084	1065	46.09	2	1032	1	1004	0.0e+00	948	COG0841	Multidrug efflux pump subunit AcrB	1009
649661086	812	16.03	203	812	140	768	1.0e-18	89.2	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
649661088	352	56.29	1	350	1	349	0.0e+00	508	COG0722	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase	351
649661089	259	53.85	1	258	2	256	3.0e-86	311	COG0084	Tat protein secretion system quality control protein TatD (DNase activity)	256
649661090	177	33.06	5	123	6	128	5.0e-12	64.6	COG3688	Predicted RNA-binding protein containing a PIN domain	173
649661091	442	29.57	184	439	6	231	1.0e-43	171	COG0860	N-acetylmuramoyl-L-alanine amidase	231
649661092	253	47.77	1	247	1	247	4.0e-80	291	COG0101	tRNA U38,U39,U40 pseudouridine synthase TruA	266
649661094	216	61.14	1	193	3	193	1.0e-69	255	COG1045	Serine acetyltransferase	194
649661095	160	51.28	4	159	1	156	2.0e-51	195	COG0245	2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	159
649661096	247	46.09	13	241	3	230	7.0e-62	230	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	230
649661097	341	52.41	48	329	70	356	4.0e-82	298	COG4956	Uncharacterized conserved protein YacL, contains PIN and TRAM domains	356
649661098	514	43.38	50	401	10	341	6.0e-74	272	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
649661099	307	31.94	16	302	6	257	7.0e-40	158	COG1830	Fructose-bisphosphate aldolase class Ia, DhnA family	265
649661100	332	52	6	330	2	324	9.0e-114	403	COG0158	Fructose-1,6-bisphosphatase	326
649661102	466	34.18	1	464	7	464	2.0e-97	350	COG1109	Phosphomannomutase	464
649661103	484	43.32	7	343	2	333	7.0e-117	414	COG0836	Mannose-1-phosphate guanylyltransferase	333
649661104	153	53.06	4	150	13	159	4.0e-47	180	COG1778	 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsC and related HAD superfamily phosphatases	170
649661105	466	40.79	239	466	1	226	2.0e-71	263	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
649661106	394	20.6	5	384	2	373	5.0e-18	85.8	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649661107	355	26.49	3	353	13	378	1.0e-32	133	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649661112	411	22.8	1	411	3	381	5.0e-26	112	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649661113	402	24.93	46	394	22	361	1.0e-15	78.3	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
649661116	332	34.92	5	311	3	306	1.0e-49	190	COG0451	Nucleoside-diphosphate-sugar epimerase	314
649661117	383	24.73	1	369	1	369	2.0e-47	183	COG0381	UDP-N-acetylglucosamine 2-epimerase	383
649661118	348	39.83	6	346	1	346	1.0e-90	326	COG2089	Sialic acid synthase SpsE, contains C-terminal SAF domain	347
649661119	230	34.96	1	220	2	222	3.0e-38	151	COG1083	CMP-N-acetylneuraminic acid synthetase	228
649661124	371	27.53	1	354	1	340	7.0e-48	184	COG0673	Predicted dehydrogenase	342
649661126	487	21.23	17	468	10	461	4.0e-13	69.7	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
649661127	180	43.43	1	175	20	189	1.0e-58	219	COG0529	Adenylylsulfate kinase or related kinase	197
649661129	610	31.54	2	610	22	535	3.0e-97	349	COG0367	Asparagine synthetase B (glutamine-hydrolyzing)	542
649661130	316	32.51	7	310	2	314	4.0e-43	168	COG0451	Nucleoside-diphosphate-sugar epimerase	314
649661131	335	66.96	3	326	5	345	0.0e+00	535	COG1089	GDP-D-mannose dehydratase	345
649661132	413	17.92	9	382	34	414	3.0e-07	50.2	COG3307	O-antigen ligase	424
649661133	283	48.93	1	275	1	280	8.0e-83	300	COG1091	dTDP-4-dehydrorhamnose reductase	281
649661134	342	52.65	1	331	1	340	5.0e-127	447	COG1088	dTDP-D-glucose 4,6-dehydratase	340
649661135	244	50	1	236	1	237	4.0e-81	294	COG1209	dTDP-glucose pyrophosphorylase	286
649661137	418	31.51	22	413	2	399	2.0e-69	256	COG0579	L-2-hydroxyglutarate oxidase LhgO	429
649661138	359	29.06	1	359	1	379	1.0e-33	137	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649661139	303	22.98	16	241	5	237	3.0e-19	89	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
649661140	338	28.57	113	305	43	242	2.0e-12	66.8	COG2227	2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase	243
649661141	299	20.28	2	280	1	271	3.0e-17	82.9	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
649661142	347	34.11	4	338	2	330	4.0e-58	218	COG0859	ADP-heptose:LPS heptosyltransferase	334
649661144	367	26.55	1	367	1	379	3.0e-38	153	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649661145	265	16.67	12	263	2	251	2.0e-12	66.3	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
649661146	267	21.46	6	253	5	262	1.0e-12	67.5	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
649661147	714	20.13	43	619	3	565	1.0e-36	148	COG1368	Phosphoglycerol transferase MdoB or a related enzyme of AlkP superfamily	650
649661148	366	28.76	1	366	3	379	2.0e-30	127	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649661149	347	33.53	5	342	1	334	3.0e-57	216	COG0859	ADP-heptose:LPS heptosyltransferase	334
649661150	563	30.29	6	344	1	326	4.0e-55	209	COG0859	ADP-heptose:LPS heptosyltransferase	334
649661151	360	38.04	8	349	11	328	2.0e-58	220	COG1663	Tetraacyldisaccharide-1-P 4'-kinase	336
649661152	452	41.59	3	430	1	419	2.0e-104	373	COG1519	3-deoxy-D-manno-octulosonic-acid transferase	419
649661154	220	35.71	21	173	8	159	8.0e-33	133	COG2121	Uncharacterized conserved protein, lysophospholipid acyltransferase (LPLAT) superfamily	214
649661155	581	43.9	4	577	1	567	0.0e+00	494	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
649661156	377	36.91	1	377	1	381	3.0e-95	342	COG0763	Lipid A disaccharide synthetase	381
649661157	329	32.92	1	300	1	325	1.0e-41	163	COG0673	Predicted dehydrogenase	342
649661158	280	39.78	14	278	4	275	1.0e-55	210	COG3494	Uncharacterized conserved protein, DUF1009 family	279
649661159	269	52.33	1	258	4	260	2.0e-92	332	COG1043	Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase	260
649661160	151	54.42	1	145	1	146	2.0e-44	171	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
649661161	183	27.01	10	179	3	168	1.0e-09	56.5	COG2825	Periplasmic chaperone for outer membrane proteins, Skp family	170
649661162	187	22.35	18	185	4	170	4.0e-11	61.1	COG2825	Periplasmic chaperone for outer membrane proteins, Skp family	170
649661163	774	28.88	16	774	6	766	4.0e-122	432	COG4775	Outer membrane protein assembly factor BamA	766
649661164	313	58.95	6	289	4	288	1.0e-119	422	COG1210	UTP-glucose-1-phosphate uridylyltransferase	291
649661165	831	57.75	12	783	1	773	0.0e+00	1073	COG0466	ATP-dependent Lon protease, bacterial type	782
649661166	349	37.76	15	345	5	317	9.0e-69	254	COG0611	Thiamine monophosphate kinase	317
649661167	159	31.94	5	142	30	170	7.0e-18	83.4	COG3216	Uncharacterized conserved protein, DUF2062 family	184
649661170	146	30.95	1	125	1	116	2.0e-15	75.3	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
649661174	227	22.75	4	226	6	229	2.0e-15	76.1	COG0638	20S proteasome, alpha and beta subunits	236
649661175	274	31.77	55	246	30	217	4.0e-31	128	COG0638	20S proteasome, alpha and beta subunits	236
649661178	208	43.33	1	207	1	209	8.0e-43	167	COG0352	Thiamine monophosphate synthase	211
649661179	259	60.78	5	259	5	259	5.0e-103	367	COG2022	Thiamin biosynthesis thiazole synthase ThiGH, ThiG subunit	262
649661180	68	42.42	1	66	3	68	3.0e-12	63.3	COG2104	Sulfur carrier protein ThiS (thiamine biosynthesis)	68
649661183	449	45.95	36	398	33	398	1.0e-100	360	COG0793	C-terminal processing protease CtpA/Prc, contains a PDZ domain	406
649661184	396	26.1	39	395	38	420	2.0e-39	157	COG4942	Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB	420
649661185	299	32.66	2	294	4	294	5.0e-44	171	COG2177	Cell division protein FtsX	297
649661186	222	57.73	1	219	1	220	3.0e-75	274	COG2884	ABC-type ATPase involved in cell division	223
649661187	128	43.59	5	120	1	113	7.0e-26	109	COG0792	Predicted endonuclease distantly related to archaeal Holliday junction resolvase	114
649661188	224	54.55	27	209	1	187	4.0e-61	227	COG0164	Ribonuclease HII	199
649661189	134	57.14	1	112	3	114	2.0e-33	134	COG0335	Ribosomal protein L19	115
649661190	257	54.88	1	245	1	238	1.0e-91	329	COG0336	tRNA G37 N-methylase TrmD	240
649661191	175	31.4	5	174	3	174	1.0e-30	125	COG0806	Ribosomal 30S subunit maturation factor RimM, required for 16S rRNA processing	174
649661192	105	52.33	2	85	1	86	2.0e-20	91.1	COG0228	Ribosomal protein S16	87
649661193	449	55.9	1	449	1	445	0.0e+00	564	COG0541	Signal recognition particle GTPase	451
649661196	665	66.57	1	664	2	663	0.0e+00	1063	COG0556	Excinuclease UvrABC helicase subunit UvrB	663
649661197	207	30.85	4	204	1	180	8.0e-28	117	COG1514	2'-5' RNA ligase	180
649661198	426	39.69	7	265	2	255	2.0e-52	200	COG1058	Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA	255
649661200	235	34.21	10	233	10	229	6.0e-45	174	COG3253	Chlorite dismutase	230
649661205	158	33.12	1	155	1	156	3.0e-24	104	COG1047	FKBP-type peptidyl-prolyl cis-trans isomerase 2	174
649661206	196	39.56	15	196	10	182	4.0e-37	148	COG3108	Uncharacterized conserved protein YcbK, DUF882 family	185
649661207	470	44.4	1	451	2	458	3.0e-120	425	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
649661210	215	39.42	8	214	2	209	2.0e-48	185	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
649661212	140	23.57	1	137	4	141	1.0e-10	58.9	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
649661213	287	26.5	7	281	9	260	7.0e-34	138	COG0300	Short-chain dehydrogenase	265
649661215	824	36.1	426	822	14	417	4.0e-64	240	COG4995	Uncharacterized conserved protein, contains CHAT domain	420
649661217	588	28.09	30	583	9	552	2.0e-77	283	COG2831	Hemolysin activation/secretion protein	554
649661219	639	32.35	47	444	9	390	1.0e-49	191	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
649661220	406	23.56	1	347	5	292	7.0e-14	72	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
649661221	262	45.95	3	259	1	257	7.0e-58	217	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
649661222	407	46.67	1	282	1	285	1.0e-84	307	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
649661223	396	42.86	1	395	1	391	2.0e-82	299	COG0183	Acetyl-CoA acetyltransferase	392
649661224	571	38.32	14	564	3	532	1.0e-128	453	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
649661225	255	17.26	1	226	9	227	2.0e-04	39.9	COG5424	Pyrroloquinoline quinone (PQQ) biosynthesis protein C	242
649661227	371	26.68	16	369	43	419	1.0e-56	213	COG3508	Homogentisate 1,2-dioxygenase	427
649661228	334	38.1	98	327	48	266	2.0e-48	186	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
649661229	253	25.31	49	205	5	154	5.0e-08	51.8	COG0461	Orotate phosphoribosyltransferase	201
649661230	333	44.98	1	326	15	343	1.0e-83	303	COG1071	TPP-dependent pyruvate or acetoin dehydrogenase subunit alpha	358
649661231	330	62.04	9	330	1	324	0.0e+00	475	COG0022	Pyruvate/2-oxoglutarate/acetoin dehydrogenase complex, dehydrogenase (E1) component	324
649661232	385	45.07	1	385	1	402	1.0e-104	373	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
649661233	394	42.43	7	394	4	391	5.0e-78	285	COG0183	Acetyl-CoA acetyltransferase	392
649661234	294	51.76	5	287	2	285	3.0e-87	315	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
649661235	531	59.81	3	529	19	548	0.0e+00	684	COG1884	Methylmalonyl-CoA mutase, N-terminal domain/subunit	548
649661236	282	27.39	51	278	29	232	1.0e-12	67.6	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
649661237	135	44.09	9	135	14	140	4.0e-32	130	COG2185	Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding)	143
649661238	537	43.07	15	530	1	516	0.0e+00	558	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component	526
649661239	282	38.31	1	259	1	257	7.0e-46	177	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
649661241	257	48.25	14	253	3	259	1.0e-68	252	COG1703	Putative periplasmic protein kinase ArgK or related GTPase of G3E family	323
649661242	467	43.02	1	441	5	431	3.0e-111	395	COG2079	2-methylcitrate dehydratase PrpD	453
649661243	313	48.94	6	286	3	279	1.0e-78	286	COG2513	2-Methylisocitrate lyase and related enzymes, PEP mutase family	289
649661244	392	45.88	10	391	7	390	1.0e-112	400	COG0372	Citrate synthase	390
649661245	570	32.23	53	560	34	531	6.0e-90	325	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
649661246	636	31.96	39	447	5	385	8.0e-57	215	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
649661248	308	30.61	12	301	27	310	8.0e-34	137	COG0668	Small-conductance mechanosensitive channel	316
649661257	514	21.6	60	467	45	443	6.0e-19	89.4	COG1538	Outer membrane protein TolC	457
649661262	183	39.11	7	178	28	198	2.0e-28	118	COG1974	SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase)	201
649661266	364	36.06	8	359	10	350	3.0e-72	265	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
649661267	224	44.6	3	215	6	218	4.0e-55	208	COG4149	ABC-type molybdate transport system, permease component	225
649661268	67	41.18	1	67	1	68	6.0e-06	42.2	COG3585	Molybdopterin-binding protein	69
649661270	253	35.43	2	253	8	258	8.0e-50	190	COG0725	ABC-type molybdate transport system, periplasmic component	258
649661273	276	25.65	9	274	4	258	1.0e-26	113	COG0725	ABC-type molybdate transport system, periplasmic component	258
649661274	409	39.2	206	404	24	219	5.0e-43	168	COG1910	Periplasmic molybdate-binding protein/domain	223
649661276	274	36.33	14	258	14	255	6.0e-46	177	COG0725	ABC-type molybdate transport system, periplasmic component	258
649661278	111	36.71	11	89	1	79	2.0e-15	74.6	COG4378	Uncharacterized protein	103
649661279	341	37.42	23	341	33	348	9.0e-80	290	COG1613	ABC-type sulfate transport system, periplasmic component	348
649661281	456	46.75	2	454	1	460	1.0e-128	453	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
649661282	210	22.35	7	169	3	155	8.0e-09	53.9	COG3576	Predicted flavin-nucleotide-binding protein, pyridoxine 5'-phosphate oxidase superfamily	173
649661283	799	57.92	15	799	8	780	0.0e+00	968	COG2183	Transcriptional accessory protein Tex/SPT6	780
649661285	627	53.54	6	627	10	627	0.0e+00	725	COG3158	K+ transporter	627
649661286	154	61.59	1	150	2	151	5.0e-61	226	COG0219	tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain	155
649661287	151	20.71	4	141	2	139	7.0e-16	76.4	COG2193	Bacterioferritin (cytochrome b1)	157
649661288	363	61.29	1	363	1	372	0.0e+00	496	COG0012	Ribosome-binding ATPase YchF, GTP1/OBG family	372
649661290	230	28.79	31	227	2	175	9.0e-27	113	COG0663	Carbonic anhydrase or acetyltransferase, isoleucine patch superfamily	176
649661294	339	47.04	2	337	3	329	0.0e+00	480	COG1087	UDP-glucose 4-epimerase	329
649661296	506	28.93	101	493	103	494	3.0e-46	179	COG0464	AAA+-type ATPase, SpoVK/Ycf46/Vps4 family	494
649661299	317	29.97	20	310	25	301	4.0e-47	182	COG2017	Galactose mutarotase or related enzyme	308
649661300	421	30.56	10	369	5	327	3.0e-58	219	COG0205	6-phosphofructokinase	347
649661301	177	33.56	31	173	2	150	1.0e-28	119	COG1047	FKBP-type peptidyl-prolyl cis-trans isomerase 2	174
649661302	442	40.41	1	439	28	460	2.0e-104	372	COG0513	Superfamily II DNA and RNA helicase	513
649661309	721	31.4	2	695	6	640	6.0e-108	385	COG3408	Glycogen debranching enzyme (alpha-1,6-glucosidase)	641
649661310	446	17.53	75	422	63	391	8.0e-07	48.7	COG2814	Predicted arabinose efflux permease, MFS family	394
649661312	426	16.95	71	418	62	389	5.0e-04	39.4	COG2814	Predicted arabinose efflux permease, MFS family	394
649661313	357	21.22	9	341	5	380	4.0e-27	115	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649661316	516	24.26	134	503	84	441	3.0e-32	133	COG1538	Outer membrane protein TolC	457
649661318	339	28.31	23	338	25	278	7.0e-31	128	COG1234	Ribonuclease BN, tRNA processing enzyme	292
649661332	257	44.31	3	253	5	259	2.0e-58	219	COG2162	Arylamine N-acetyltransferase	275
649661333	941	50.59	12	928	4	935	0.0e+00	1162	COG0178	Excinuclease UvrABC ATPase subunit	935
649661334	186	36.31	7	169	14	180	6.0e-36	143	COG1678	Putative transcriptional regulator, AlgH/UPF0301 family	194
649661335	263	33.09	1	263	3	271	8.0e-44	170	COG0388	Predicted amidohydrolase	274
649661337	297	30.5	1	274	7	282	9.0e-52	197	COG2897	3-mercaptopyruvate sulfurtransferase SseA, contains two rhodanese domains	285
649661339	314	51.76	1	311	1	309	4.0e-92	331	COG0123	Acetoin utilization deacetylase AcuC or a related deacetylase	340
649661342	605	30.34	26	605	13	597	2.0e-104	373	COG1164	Oligoendopeptidase F	598
649661348	120	55.65	1	115	3	116	2.0e-34	137	COG3189	Uncharacterized conserved protein YeaO, DUF488 family	117
649661350	218	19.9	1	201	5	205	3.0e-09	55.3	COG5278	Extracellular (periplasmic) sensor domain CHASE3 (specificity unknown)	207
649661353	506	39.62	7	501	32	546	9.0e-114	404	COG3604	Transcriptional regulator containing GAF, AAA-type ATPase, and DNA-binding Fis domains	550
649661354	515	34.9	28	367	5	345	8.0e-72	264	COG1566	Multidrug resistance efflux pump	352
649661355	502	31.63	20	490	1	448	4.0e-52	199	COG1538	Outer membrane protein TolC	457
649661357	293	33.46	1	254	3	251	6.0e-33	134	COG2116	Formate/nitrite transporter FocA, FNT family	265
649661359	651	31.45	358	634	60	333	3.0e-35	143	COG0642	Signal transduction histidine kinase	336
649661360	463	45.63	1	458	3	453	1.0e-124	440	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
649661361	380	26.98	8	374	12	364	9.0e-44	171	COG4585	Signal transduction histidine kinase	365
649661362	214	42.31	6	211	2	208	5.0e-45	174	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
649661364	480	23.41	54	478	8	444	2.0e-31	131	COG1538	Outer membrane protein TolC	457
649661365	410	26.98	64	403	32	361	5.0e-22	99	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
649661366	1043	47.78	1	1035	1	1025	0.0e+00	1124	COG3696	Cu/Ag efflux pump CusA	1027
649661367	104	50.96	1	104	2	105	1.0e-22	97.8	COG2076	Multidrug transporter EmrE and related cation transporters	106
649661368	395	38.34	69	393	42	365	5.0e-57	215	COG0387	Ca2+/H+ antiporter	368
649661369	473	40.09	10	468	6	454	2.0e-115	410	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
649661372	68	32.79	1	61	1	59	4.0e-04	36.4	COG2906	Bacterioferritin-associated ferredoxin	63
649661373	210	30.29	31	196	4	207	5.0e-21	94.4	COG0655	Multimeric flavodoxin WrbA	207
649661375	170	41.67	48	167	6	119	1.0e-27	116	COG1430	Uncharacterized conserved membrane protein, UPF0127 family	126
649661377	727	46.12	1	720	1	701	0.0e+00	836	COG0317	(p)ppGpp synthase/hydrolase, HD superfamily	701
649661378	568	42.31	54	541	12	491	8.0e-110	391	COG0608	Single-stranded DNA-specific exonuclease, DHH superfamily, may be involved in archaeal DNA replication intiation	491
649661380	684	56.2	4	684	3	701	0.0e+00	688	COG3808	Na+ or H+-translocating membrane pyrophosphatase	703
649661387	97	23.66	3	94	2	94	3.0e-09	53.8	COG1826	Sec-independent protein translocase protein TatA	94
649661393	325	18.96	36	244	9	183	4.0e-09	55.8	COG3381	Cytoplasmic chaperone TorD involved in molybdoenzyme TorA maturation	204
649661397	483	43.01	1	479	2	464	7.0e-121	427	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
649661398	1058	34.43	813	1051	94	333	4.0e-37	151	COG0642	Signal transduction histidine kinase	336
649661399	305	45.36	4	294	4	289	3.0e-64	238	COG0341	Preprotein translocase subunit SecF	305
649661400	549	44	1	549	2	506	9.0e-118	417	COG0342	Preprotein translocase subunit SecD	506
649661401	106	49.46	13	105	1	93	8.0e-24	102	COG1862	Preprotein translocase subunit YajC	97
649661402	385	54.42	6	366	1	362	0.0e+00	477	COG0343	Queuine/archaeosine tRNA-ribosyltransferase	372
649661403	584	35.9	33	584	25	577	0.0e+00	510	COG0018	Arginyl-tRNA synthetase	577
649661404	344	23.39	14	339	4	334	5.0e-28	118	COG0859	ADP-heptose:LPS heptosyltransferase	334
649661405	206	32.45	10	195	6	185	2.0e-30	125	COG0746	Molybdopterin-guanine dinucleotide biosynthesis protein A	192
649661406	594	19.5	12	168	9	138	9.0e-05	42.6	COG2010	Cytochrome c, mono- and diheme variants	150
649661411	317	32.98	41	285	31	310	8.0e-35	141	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
649661412	304	29.77	28	297	6	313	3.0e-39	155	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
649661421	473	29.37	206	461	38	303	1.0e-15	78.4	COG1413	HEAT repeat	335
649661426	604	17.75	51	449	36	447	2.0e-20	94.1	COG0531	Amino acid transporter	466
649661431	680	39.81	177	673	30	546	4.0e-117	415	COG3604	Transcriptional regulator containing GAF, AAA-type ATPase, and DNA-binding Fis domains	550
649661433	376	20.1	3	376	8	406	2.0e-09	57.2	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
649661434	255	40.18	26	243	2	220	9.0e-65	240	COG1136	ABC-type lipoprotein export system, ATPase component	226
649661436	506	37.16	20	498	1	455	9.0e-70	258	COG1538	Outer membrane protein TolC	457
649661440	192	35.8	9	180	4	170	2.0e-27	115	COG1045	Serine acetyltransferase	194
649661441	665	37.52	103	631	20	551	8.0e-126	444	COG3882	Predicted enzyme involved in methoxymalonyl-ACP biosynthesis	574
649661442	504	23.87	269	485	2	221	5.0e-19	89.5	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
649661443	78	20.83	1	72	4	75	4.0e-06	43	COG0236	Acyl carrier protein	80
649661444	423	45.02	3	251	1	239	8.0e-78	284	COG1134	ABC-type polysaccharide/polyol phosphate transport system, ATPase component	249
649661446	224	23.74	28	222	60	241	3.0e-13	68.8	COG3751	Proline 4-hydroxylase (includes Rps23 Pro-64 3,4-dihydroxylase Tpa1), contains SM-20 domain	252
649661449	242	42.31	4	234	3	236	2.0e-60	225	COG1131	ABC-type multidrug transport system, ATPase component	293
649661450	234	23.33	6	163	19	182	3.0e-09	55.8	COG3005	Tetraheme cytochrome c subunit of nitrate or TMAO reductase	190
649661451	169	42.86	4	159	3	161	5.0e-33	133	COG1763	Molybdopterin-guanine dinucleotide biosynthesis protein	161
649661452	432	44.33	9	412	5	403	8.0e-113	400	COG0303	Molybdopterin biosynthesis enzyme	404
649661453	318	37.1	52	269	54	261	8.0e-44	171	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
649661454	314	36.54	18	277	2	251	4.0e-48	185	COG0805	Sec-independent protein secretion pathway component TatC	255
649661455	511	41.09	11	395	1	345	5.0e-67	248	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
649661459	607	45.96	31	596	1	553	0.0e+00	529	COG2192	Predicted carbamoyl transferase, NodU family	555
649661462	317	25.29	1	257	1	258	7.0e-24	104	COG1426	Cytoskeletal protein RodZ, contains Xre-like HTH and DUF4115 domains	284
649661463	233	26.89	19	222	2	208	2.0e-16	79.6	COG3063	Tfp pilus assembly protein PilF	250
649661464	305	24.44	3	293	1	309	4.0e-21	95.6	COG0524	Sugar or nucleoside kinase, ribokinase family	311
649661465	299	44.09	5	253	12	262	7.0e-72	264	COG0005	Purine nucleoside phosphorylase	262
649661466	343	41.61	10	307	1	298	3.0e-85	309	COG0324	tRNA A37 N6-isopentenylltransferase MiaA	308
649661467	599	38.93	9	598	3	637	0.0e+00	532	COG0323	DNA mismatch repair ATPase MutL	638
649661468	259	29.23	5	259	18	262	3.0e-31	128	COG1729	Periplasmic TolA-binding protein (function unknown)	262
649661469	558	27.56	331	555	52	262	5.0e-21	96.2	COG1729	Periplasmic TolA-binding protein (function unknown)	262
649661470	250	29.38	92	250	31	190	7.0e-27	114	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
649661471	443	31.78	19	441	6	423	2.0e-66	246	COG0823	Periplasmic component of the Tol biopolymer transport system	425
649661472	411	22.99	220	392	55	228	5.0e-05	42.8	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
649661473	150	41.22	5	134	7	137	1.0e-27	115	COG0848	Biopolymer transport protein ExbD	137
649661474	240	30.88	16	230	8	212	4.0e-31	128	COG0811	Biopolymer transport protein ExbB/TolQ	216
649661477	299	48.31	1	295	5	300	2.0e-90	326	COG4974	Site-specific recombinase XerD	300
649661478	664	30	289	659	10	355	3.0e-41	164	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
649661479	329	44.94	1	311	1	314	4.0e-100	357	COG0180	Tryptophanyl-tRNA synthetase	314
649661481	168	37.5	50	168	24	143	2.0e-23	102	COG1259	Bifunctional DNase/RNase	151
649661482	209	34.26	1	208	12	227	2.0e-28	118	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
649661485	305	28.17	1	300	6	314	4.0e-32	132	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
649661495	477	46.1	23	473	2	456	0.0e+00	480	COG0493	NADPH-dependent glutamate synthase beta chain or related oxidoreductase	457
649661496	1506	58.94	710	1197	1	483	0.0e+00	675	COG0069	Glutamate synthase domain 2	485
649661497	334	37.77	18	333	5	321	4.0e-72	264	COG0142	Geranylgeranyl pyrophosphate synthase	322
649661498	440	20.71	2	439	1	405	3.0e-32	133	COG4198	Uncharacterized conserved protein, DUF1015 family	405
649661499	458	47.91	1	451	3	453	0.0e+00	472	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
649661501	366	33.13	41	362	16	342	3.0e-41	162	COG3178	Predicted phosphotransferase, aminoglycoside/choline kinase (APH/ChoK) family	351
649661502	323	44.79	1	318	1	316	2.0e-84	306	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
649661503	142	25.21	10	128	20	131	2.0e-07	48.4	COG5652	VanZ like family protein (function unknown)	148
649661504	734	24.82	1	539	1	497	2.0e-64	241	COG1449	Alpha-amylase/alpha-mannosidase, GH57 family	615
649661505	333	34.5	1	331	1	329	1.0e-61	230	COG1085	Galactose-1-phosphate uridylyltransferase	338
649661508	305	30.77	18	300	1	270	1.0e-40	160	COG0037	tRNA(Ile)-lysidine synthase TilS/MesJ	298
649661510	462	26.98	51	422	23	393	7.0e-41	161	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
649661511	303	42.32	9	301	5	295	2.0e-66	246	COG1175	ABC-type sugar transport system, permease component	295
649661512	271	42.7	1	270	8	281	9.0e-56	210	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
649661513	366	52.56	1	352	1	335	3.0e-119	421	COG3839	ABC-type sugar transport system, ATPase component	338
649661514	343	39.39	6	326	4	351	1.0e-76	280	COG0484	DnaJ-class molecular chaperone with C-terminal Zn finger domain	371
649661515	215	37.25	1	204	1	198	2.0e-28	119	COG2095	Small neutral amino acid transporter SnatA, MarC family	203
649661516	204	23.39	54	177	38	158	1.0e-06	46.5	COG3678	Periplasmic protein refolding chaperone Spy/CpxP family	160
649661518	557	49.82	1	556	5	570	0.0e+00	671	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
649661520	712	55.49	32	710	8	686	0.0e+00	899	COG0855	Polyphosphate kinase	696
649661521	143	28.81	12	128	2	119	3.0e-12	64.7	COG1734	RNA polymerase-binding transcription factor DksA	120
649661525	671	23.89	11	356	1	342	4.0e-35	143	COG0673	Predicted dehydrogenase	342
649661526	331	37.98	1	126	3	130	5.0e-18	85.7	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
649661527	590	42.29	366	589	2	221	3.0e-49	190	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
649661529	372	44.27	3	368	1	370	4.0e-109	388	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
649661530	396	26.97	1	380	2	379	8.0e-32	131	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649661531	436	24.22	1	431	2	443	4.0e-47	182	COG1232	Protoporphyrinogen oxidase	444
649661532	352	28.12	1	302	2	316	2.0e-33	136	COG0472	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase	319
649661533	379	20.67	1	356	4	381	2.0e-14	73.5	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649661534	608	28.38	343	567	2	226	6.0e-26	112	COG1216	Glycosyltransferase, GT2 family	305
649661537	342	43.27	1	342	1	333	3.0e-101	362	COG2605	Predicted kinase related to galactokinase and mevalonate kinase	333
649661542	1285	34.65	406	626	1	226	2.0e-37	152	COG1216	Glycosyltransferase, GT2 family	305
649661544	449	45.45	6	257	3	249	2.0e-78	287	COG1134	ABC-type polysaccharide/polyol phosphate transport system, ATPase component	249
649661545	274	36.08	20	274	16	263	1.0e-32	133	COG1682	ABC-type polysaccharide/polyol phosphate export permease	263
649661547	323	36.16	1	304	2	289	3.0e-72	265	COG1131	ABC-type multidrug transport system, ATPase component	293
649661549	665	15.84	4	396	17	413	7.0e-08	52.8	COG3307	O-antigen ligase	424
649661550	179	32.59	5	129	2	136	1.0e-12	66.2	COG4968	Tfp pilus assembly protein PilE	139
649661553	451	52.41	13	446	1	434	0.0e+00	505	COG0305	Replicative DNA helicase	435
649661554	369	35.51	16	366	2	349	3.0e-60	225	COG3705	ATP phosphoribosyltransferase regulatory subunit HisZ	390
649661555	530	48.77	1	322	4	324	1.0e-91	331	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
649661556	381	49.6	2	377	4	381	1.0e-119	423	COG0075	Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism protein PucG	383
649661559	386	49.61	1	380	6	388	3.0e-122	431	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
649661560	353	59.09	1	351	2	353	0.0e+00	505	COG2805	Tfp pilus assembly protein PilT, pilus retraction ATPase	353
649661561	387	55.07	1	364	5	369	2.0e-124	438	COG5008	Tfp pilus assembly protein, ATPase PilU	375
649661563	285	33.22	21	284	26	314	3.0e-35	142	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
649661569	722	48.72	15	715	8	708	0.0e+00	772	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
649661572	189	45.09	16	187	9	172	4.0e-41	161	COG3040	Bacterial lipocalin	174
649661577	637	55.59	8	635	3	628	0.0e+00	728	COG0296	1,4-alpha-glucan branching enzyme	628
649661580	398	27.45	3	388	31	401	8.0e-27	115	COG3673	Uncharacterized protein, PA2063/DUF2235 family	423
649661585	477	38.1	10	469	1	457	3.0e-63	236	COG1538	Outer membrane protein TolC	457
649661586	1059	49.71	1	1032	1	1009	0.0e+00	988	COG0841	Multidrug efflux pump subunit AcrB	1009
649661587	398	30.47	1	380	1	372	9.0e-30	124	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
649661591	142	38.89	1	124	1	123	1.0e-33	135	COG3795	Uncharacterized conserved protein	123
649661592	161	46.1	1	151	3	148	2.0e-40	158	COG3865	Glyoxalase superfamily enzyme, possibly 3-demethylubiquinone-9 3-methyltransferase	151
649661595	119	38.26	1	115	1	115	9.0e-23	98.8	COG3795	Uncharacterized conserved protein	123
649661596	118	49.12	1	114	1	114	2.0e-30	124	COG3795	Uncharacterized conserved protein	123
649661597	137	33.33	18	134	9	127	1.0e-22	98.4	COG3324	Predicted enzyme related to lactoylglutathione lyase	127
649661598	121	26.85	12	117	16	123	9.0e-07	45.7	COG3324	Predicted enzyme related to lactoylglutathione lyase	127
649661599	416	59.26	13	415	7	411	2.0e-125	442	COG4941	Predicted RNA polymerase sigma factor, contains C-terminal TPR domain	415
649661600	107	48.45	13	107	16	111	1.0e-23	101	COG2151	Metal-sulfur cluster biosynthetic enzyme	111
649661603	481	37.74	10	468	1	456	4.0e-59	222	COG1538	Outer membrane protein TolC	457
649661605	1027	36.45	3	1005	1	1009	0.0e+00	778	COG0841	Multidrug efflux pump subunit AcrB	1009
649661606	374	25.54	10	355	3	365	5.0e-15	75.5	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
649661608	318	29.59	7	199	11	206	7.0e-27	114	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
649661610	866	43.59	366	866	32	549	0.0e+00	472	COG3604	Transcriptional regulator containing GAF, AAA-type ATPase, and DNA-binding Fis domains	550
649661612	182	49.18	1	180	3	185	1.0e-48	186	COG1704	Uncharacterized conserved protein	185
649661613	590	17.41	26	590	9	595	3.0e-12	67.3	COG4907	Uncharacterized membrane protein	595
649661619	188	34.25	8	182	2	182	1.0e-24	106	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
649661623	619	26.09	133	590	53	450	4.0e-47	183	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
649661625	353	28.44	57	330	1	315	5.0e-38	152	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
649661626	227	18.6	7	204	6	219	8.0e-07	47.6	COG1011	FMN phosphatase YigB, HAD superfamily	229
649661627	791	70.19	5	788	9	792	0.0e+00	1215	COG3957	Phosphoketolase	793
649661628	404	45.73	9	401	1	396	3.0e-127	448	COG0282	Acetate kinase	396
649661630	253	27.84	7	252	1	244	2.0e-29	122	COG1651	Protein-disulfide isomerase	244
649661632	473	43.43	1	469	1	456	3.0e-128	452	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
649661633	677	23.24	22	660	8	603	1.0e-43	171	COG4191	Signal transduction histidine kinase regulating C4-dicarboxylate transport system	603
649661634	267	25.19	59	189	17	143	2.0e-06	47	COG3212	Uncharacterized membrane protein YkoI	144
649661635	308	18.91	51	300	5	263	7.0e-07	48.5	COG5266	Uncharacterized conserved protein, contains GH25 family domain	264
649661636	819	26.06	176	819	50	753	2.0e-75	277	COG4772	Outer membrane receptor for Fe3+-dicitrate	753
649661637	311	40.45	3	311	16	320	3.0e-55	209	COG3712	Periplasmic ferric-dicitrate binding protein FerR, regulates iron transport through sigma-19	322
649661638	167	30.43	1	160	15	175	5.0e-24	104	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
649661639	1033	39.45	2	1017	1	1009	0.0e+00	953	COG0841	Multidrug efflux pump subunit AcrB	1009
649661640	1037	39.13	2	1014	1	1008	0.0e+00	906	COG0841	Multidrug efflux pump subunit AcrB	1009
649661641	412	34.66	42	389	27	371	3.0e-31	129	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
649661643	298	36	1	297	1	296	2.0e-37	149	COG0583	DNA-binding transcriptional regulator, LysR family	297
649661644	274	29.43	9	271	1	259	3.0e-25	108	COG3217	Uncharacterized conserved protein YcbX, contains MOSC and Fe-S domains	270
649661645	244	47.64	30	220	17	206	5.0e-54	204	COG2258	Uncharacterized conserved protein YiiM, contains MOSC domain	210
649661649	362	48.35	17	198	8	187	4.0e-55	208	COG2169	Methylphosphotriester-DNA--protein-cysteine methyltransferase (N-terminal fragment of Ada), contains Zn-binding and two AraC-type DNA-binding domains	187
649661657	106	32.73	2	53	13	66	3.0e-03	33.7	COG3311	Predicted DNA-binding transcriptional regulator AlpA	70
649661658	361	25.94	78	329	28	291	2.0e-19	90.7	COG4974	Site-specific recombinase XerD	300
649661660	440	56.88	1	428	1	429	0.0e+00	613	COG0104	Adenylosuccinate synthase	430
649661664	613	42.86	1	488	3	530	0.0e+00	485	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
649661666	429	52.76	12	428	1	413	0.0e+00	528	COG2256	Replication-associated recombination protein RarA (DNA-dependent ATPase)	436
649661667	267	31.56	1	262	3	282	1.0e-25	110	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
649661668	211	58.06	19	204	9	194	2.0e-74	271	COG0302	GTP cyclohydrolase I	195
649661669	149	31.85	6	135	5	126	8.0e-15	73.1	COG0720	6-pyruvoyl-tetrahydropterin synthase	127
649661671	106	50.94	1	105	4	109	8.0e-34	135	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
649661672	118	38.46	1	101	1	102	7.0e-14	69.3	COG0633	Ferredoxin	102
649661673	425	54.11	8	408	22	421	0.0e+00	532	COG1894	NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F)	424
649661675	313	42.63	4	311	1	311	2.0e-91	329	COG0039	Malate/lactate dehydrogenase	313
649661678	148	31.73	5	104	2	102	3.0e-16	77.7	COG4802	Ferredoxin-thioredoxin reductase, catalytic subunit	110
649661681	105	45.26	10	102	3	97	2.0e-18	83.8	COG1872	Uncharacterized conserved protein YggU, UPF0235/DUF167 family	102
649661682	279	26.09	17	259	15	263	9.0e-27	114	COG0714	MoxR-like ATPase	329
649661684	476	21.52	177	475	3	292	5.0e-18	86.2	COG4866	Uncharacterized protein	294
649661687	377	49.02	2	350	14	369	7.0e-107	380	COG1509	L-lysine 2,3-aminomutase (EF-P beta-lysylation pathway)	369
649661688	383	18.99	226	383	37	182	8.0e-16	78.4	COG0717	Deoxycytidine triphosphate deaminase	183
649661690	238	17.83	1	228	3	224	3.0e-11	62.5	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
649661691	250	37.5	16	222	7	209	4.0e-30	125	COG3222	Uncharacterized conserved protein, glycosyltransferase A (GT-A) superfamily, DUF2064 family	211
649661692	244	38.34	1	242	3	250	5.0e-35	141	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
649661693	487	24.83	198	486	9	288	3.0e-26	113	COG0382	4-hydroxybenzoate polyprenyltransferase	289
649661694	108	36.89	3	104	2	104	1.0e-21	94.9	COG0278	Glutaredoxin-related protein	105
649661695	97	36.05	17	94	2	86	1.0e-12	65	COG0271	Stress-induced morphogen (activity unknown)	90
649661701	360	25.57	1	347	8	342	6.0e-28	118	COG0628	Predicted PurR-regulated permease PerM	355
649661702	164	34.68	7	130	1	122	4.0e-19	87.7	COG1664	Cytoskeletal protein CcmA, bactofilin family	146
649661703	767	42.36	142	738	61	634	0.0e+00	508	COG0744	Membrane carboxypeptidase (penicillin-binding protein)	661
649661704	441	23.97	9	441	21	438	2.0e-26	114	COG2067	Long-chain fatty acid transport protein	440
649661707	487	26.95	1	463	4	475	8.0e-49	188	COG0591	Na+/proline symporter	493
649661710	316	26.27	7	258	3	232	2.0e-13	69.9	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
649661714	314	58.1	4	314	10	324	1.0e-122	432	COG0435	Glutathionyl-hydroquinone reductase	324
649661715	225	44.83	27	222	3	204	2.0e-44	172	COG0545	FKBP-type peptidyl-prolyl cis-trans isomerase	205
649661716	307	30.77	8	180	3	174	4.0e-20	92.3	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
649661718	307	28.47	27	302	9	261	8.0e-35	141	COG0300	Short-chain dehydrogenase	265
649661722	341	19.44	129	340	52	262	7.0e-06	45.4	COG3137	Putative salt-induced outer membrane protein YdiY	262
649661723	436	38.15	5	421	3	404	1.0e-93	337	COG2081	Predicted flavoprotein YhiN	408
649661724	260	28.63	4	247	1	248	2.0e-23	102	COG0388	Predicted amidohydrolase	274
649661725	186	47.37	14	183	6	176	2.0e-51	195	COG3545	Predicted esterase of the alpha/beta hydrolase fold	181
649661726	412	34.63	1	403	4	407	1.0e-104	373	COG2081	Predicted flavoprotein YhiN	408
649661728	156	25.53	17	151	20	156	2.0e-06	45	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
649661729	213	18.86	25	185	17	178	8.0e-05	40.7	COG3047	Outer membrane protein W	213
649661730	538	34.86	1	426	2	421	8.0e-53	201	COG0025	NhaP-type Na+/H+ or K+/H+ antiporter	429
649661731	278	29.56	3	273	7	259	3.0e-41	162	COG0656	Aldo/keto reductase, related to diketogulonate reductase	280
649661733	201	22.71	1	179	6	211	7.0e-11	61	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
649661734	650	33.33	1	261	9	262	1.0e-37	151	COG3267	Type II secretory pathway, component ExeA (predicted ATPase)	269
649661735	371	47.83	100	260	1	160	9.0e-40	157	COG4335	3-methyladenine DNA glycosylase AlkC	167
649661736	130	46.34	49	130	24	103	2.0e-13	67.9	COG0023	Translation initiation factor 1 (eIF-1/SUI1)	104
649661737	184	43.33	1	180	1	180	3.0e-53	201	COG4681	Uncharacterized conserved protein YaeQ, suppresses RfaH defect	181
649661743	542	52.77	10	530	2	522	0.0e+00	710	COG4108	Peptide chain release factor RF-3	528
649661747	520	21.88	11	360	36	375	2.0e-35	143	COG1061	Superfamily II DNA or RNA helicase	442
649661749	576	40	18	502	28	512	1.0e-116	413	COG0513	Superfamily II DNA and RNA helicase	513
649661750	227	34.2	20	212	1	171	2.0e-33	135	COG0221	Inorganic pyrophosphatase	171
649661753	163	32.81	27	152	1	117	4.0e-15	74.4	COG0517	CBS domain	117
649661756	243	31.91	35	221	26	213	2.0e-26	112	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
649661757	271	21.57	24	268	9	214	4.0e-05	42.3	COG2857	Cytochrome c1	250
649661759	153	26.06	9	150	7	144	5.0e-11	60.8	COG3305	Uncharacterized membrane protein, DUF2068 family	152
649661760	119	23.01	1	113	1	110	6.0e-06	43	COG3631	Ketosteroid isomerase-related protein	133
649661761	125	42.98	1	118	38	157	7.0e-28	116	COG3265	Gluconate kinase	161
649661763	82	54.43	3	81	5	83	2.0e-22	97.3	COG2827	Predicted endonuclease, GIY-YIG superfamily	95
649661770	412	27.68	60	411	51	388	4.0e-18	86	COG2814	Predicted arabinose efflux permease, MFS family	394
649661771	304	27.24	8	293	12	301	2.0e-21	96.5	COG0679	Predicted permease	311
649661787	285	34.96	11	221	11	231	1.0e-30	126	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
649661789	139	35.79	22	114	7	101	1.0e-12	65.7	COG3070	Transcriptional regulator of competence genes, TfoX/Sxy family	121
649661791	194	22.78	8	184	25	194	1.0e-05	43.5	COG3806	Anti-sigma factor ChrR, cupin superfamily	216
649661792	198	34.07	17	198	1	181	1.0e-24	106	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
649661793	158	26.83	35	153	6	127	1.0e-13	69.2	COG2346	Truncated hemoglobin YjbI	133
649661795	98	35.71	3	70	4	73	2.0e-06	44.6	COG2161	Antitoxin component YafN of the YafNO toxin-antitoxin module, PHD/YefM family	86
649661796	95	25.58	2	84	1	86	1.0e-05	41	COG2026	mRNA-degrading endonuclease RelE, toxin component of the RelBE toxin-antitoxin system	90
649661807	121	42.31	19	95	16	93	2.0e-08	51.3	COG0640	DNA-binding transcriptional regulator, ArsR family	110
649661808	346	23.08	50	332	20	313	3.0e-15	76.2	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
649661809	398	30.95	21	395	1	323	7.0e-38	151	COG0306	Phosphate/sulfate permease	326
649661811	174	27.01	2	163	7	171	3.0e-09	55.2	COG0723	Rieske Fe-S protein	177
649661814	138	45	1	133	1	139	3.0e-34	137	COG0394	Protein-tyrosine-phosphatase	139
649661815	353	41.91	3	348	6	337	1.0e-77	283	COG0798	Arsenite efflux pump ArsB, ACR3 family	342
649661816	274	34.48	77	229	52	224	5.0e-22	98.4	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
649661817	111	41.24	13	108	11	107	1.0e-11	61.4	COG0640	DNA-binding transcriptional regulator, ArsR family	110
649661818	345	28.47	39	323	7	282	1.0e-36	147	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
649661819	286	29.47	7	283	3	283	2.0e-36	146	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
649661820	560	55.95	2	559	1	553	0.0e+00	734	COG2759	Formyltetrahydrofolate synthetase	554
649661821	339	31.31	146	333	60	257	6.0e-29	121	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
649661822	109	46.53	8	108	4	104	3.0e-27	113	COG1324	Uncharacterized protein involved in tolerance to divalent cations	104
649661824	106	39.45	1	106	2	110	1.0e-19	87.7	COG0607	Rhodanese-related sulfurtransferase	110
649661825	307	40.51	1	304	1	310	2.0e-68	252	COG0451	Nucleoside-diphosphate-sugar epimerase	314
649661826	251	50.21	9	251	2	244	3.0e-78	285	COG1189	Predicted rRNA methylase YqxC, contains S4 and FtsJ domains	245
649661827	82	46.15	1	65	7	71	8.0e-09	51.9	COG1722	Exonuclease VII small subunit	81
649661828	452	45.58	12	450	6	440	3.0e-121	428	COG1570	Exonuclease VII, large subunit	440
649661829	259	55.77	1	259	1	259	2.0e-96	345	COG1692	Calcineurin-like phosphoesterase	266
649661830	525	48.88	304	525	1	222	2.0e-41	164	COG1418	HD superfamily phosphodieaserase, includes HD domain of RNase Y	222
649661832	98	24.18	3	92	2	92	2.0e-08	50.7	COG3027	Cell division protein ZapA, inhibits GTPase activity of FtsZ	105
649661835	366	49.27	13	348	1	339	3.0e-106	378	COG0820	Adenine C2-methylase RlmN of 23S rRNA A2503 and tRNA A37	349
649661836	451	32.49	15	441	4	434	5.0e-76	278	COG0612	Predicted Zn-dependent peptidase	438
649661837	441	31.95	10	438	1	435	7.0e-84	304	COG0612	Predicted Zn-dependent peptidase	438
649661838	273	47.31	6	265	2	258	6.0e-70	257	COG1606	ATP-utilizing enzyme, PP-loop superfamily	269
649661839	170	35.67	6	162	2	158	3.0e-19	88.4	COG0711	FoF1-type ATP synthase, membrane subunit b or b'	161
649661841	249	35.22	1	242	3	246	5.0e-38	151	COG0356	FoF1-type ATP synthase, membrane subunit a	246
649661843	477	44.38	1	475	3	456	0.0e+00	465	COG0147	Anthranilate/para-aminobenzoate synthases component I	462
649661844	293	37.19	1	283	2	278	4.0e-61	228	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
649661846	554	47.87	1	515	1	507	0.0e+00	534	COG0029	Aspartate oxidase	518
649661850	576	42.86	1	567	1	561	0.0e+00	481	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
649661852	904	43.2	9	895	20	915	0.0e+00	824	COG0474	Magnesium-transporting ATPase (P-type)	917
649661857	338	24.85	1	337	8	318	2.0e-21	96.4	COG0530	Ca2+/Na+ antiporter	320
649661858	504	30.43	121	368	101	336	4.0e-33	136	COG0642	Signal transduction histidine kinase	336
649661859	841	33.67	11	836	30	917	0.0e+00	589	COG0474	Magnesium-transporting ATPase (P-type)	917
649661860	1042	48.35	1	1031	1	1021	0.0e+00	1121	COG3696	Cu/Ag efflux pump CusA	1027
649661861	382	32.15	37	371	32	361	3.0e-29	122	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
649661862	284	35.86	154	284	7	151	2.0e-12	66.5	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
649661864	154	35.82	21	145	20	152	2.0e-23	101	COG2153	Predicted N-acyltransferase, GNAT family	155
649661865	150	34.4	7	129	1	124	1.0e-17	82.7	COG4933	Predicted transcriptional regulator, contains an HTH and PUA-like domains	124
649661867	234	17.84	14	225	3	231	7.0e-05	41.1	COG2801	Transposase InsO and inactivated derivatives	232
649661873	636	28.49	1	636	13	628	4.0e-78	286	COG0296	1,4-alpha-glucan branching enzyme	628
649661874	179	36.69	9	175	23	191	3.0e-35	141	COG0529	Adenylylsulfate kinase or related kinase	197
649661877	181	39.62	124	175	14	66	9.0e-08	50.1	COG1278	Cold shock protein, CspA family	67
649661878	804	31.88	182	788	54	642	1.0e-117	417	COG1067	Predicted ATP-dependent protease	647
649661881	193	34.64	9	178	7	185	4.0e-32	131	COG1335	Nicotinamidase-related amidase	205
649661882	444	39.47	2	406	9	405	6.0e-92	331	COG1488	Nicotinic acid phosphoribosyltransferase	405
649661883	476	41.56	115	341	14	236	1.0e-24	108	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
649661886	404	24.24	9	401	4	391	9.0e-16	78.3	COG2814	Predicted arabinose efflux permease, MFS family	394
649661887	144	33.61	18	133	1	117	4.0e-13	67.5	COG0517	CBS domain	117
649661890	326	30.32	24	176	4	153	2.0e-11	63.8	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
649661891	932	37.61	23	920	40	917	0.0e+00	726	COG0474	Magnesium-transporting ATPase (P-type)	917
649661895	249	46.69	1	237	7	248	2.0e-50	192	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
649661903	195	31.94	5	192	3	185	3.0e-34	138	COG2249	Putative NADPH-quinone reductase (modulator of drug activity B)	189
649661907	213	35.71	22	200	13	193	2.0e-29	122	COG3647	Uncharacterized membrane protein YjdF	205
649661908	212	33.33	6	196	8	200	3.0e-29	122	COG3647	Uncharacterized membrane protein YjdF	205
649661911	242	34.94	5	238	3	248	7.0e-57	213	COG0396	Fe-S cluster assembly ATPase SufC	251
649661912	311	23.72	4	311	89	388	8.0e-38	150	COG0719	Fe-S cluster assembly scaffold protein SufB	412
649661914	374	22.73	7	371	32	382	2.0e-15	76.9	COG5653	Acetyltransferase involved in cellulose biosynthesis, CelD/BcsL family	406
649661916	723	24.37	475	671	39	233	1.0e-12	69.3	COG5010	Flp pilus assembly protein TadD, contains TPR repeats	257
649661922	145	22.03	32	138	25	135	5.0e-03	33.8	COG3474	Cytochrome c2	135
649661923	329	33.45	29	295	69	339	2.0e-27	116	COG2843	Poly-gamma-glutamate biosynthesis protein CapA/YwtB (capsule formation), metallophosphatase superfamily	372
649661924	151	22.95	12	128	15	136	3.0e-04	38	COG3402	Uncharacterized membrane protein YdbS, contains bPH2 (bacterial pleckstrin homology) domain	161
649661925	331	28.42	12	299	4	284	5.0e-41	161	COG0836	Mannose-1-phosphate guanylyltransferase	333
649661926	153	51.61	1	153	21	173	5.0e-45	173	COG1881	Uncharacterized conserved protein, phosphatidylethanolamine-binding protein (PEBP) family	174
649661930	1417	33.5	139	540	1	390	8.0e-75	276	COG1924	Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain)	396
649661931	208	24.87	15	200	9	201	2.0e-21	96.1	COG2854	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic MlaC component	202
649661940	161	56.79	1	161	1	162	5.0e-53	200	COG1839	Adenosine/AMP kinase	162
649661941	294	29.05	150	294	7	152	3.0e-11	63.1	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
649661944	93	39.36	1	93	1	94	1.0e-23	101	COG3549	Plasmid maintenance system killer protein	94
649661945	104	52.58	8	104	2	97	1.0e-25	108	COG3093	Plasmid maintenance system antidote protein VapI, contains XRE-type HTH domain	104
649661948	447	47.38	16	413	19	412	0.0e+00	462	COG0281	Malic enzyme	432
649661949	576	46.48	1	324	1	326	9.0e-82	298	COG1796	DNA polymerase/3'-5' exonuclease PolX	326
649661952	448	48.64	11	447	8	449	2.0e-130	459	COG2403	Predicted GTPase	449
649661953	586	39.74	43	583	4	528	0.0e+00	510	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
649661954	324	50	4	320	23	342	9.0e-98	350	COG1071	TPP-dependent pyruvate or acetoin dehydrogenase subunit alpha	358
649661955	324	48.14	3	323	1	322	1.0e-118	419	COG0022	Pyruvate/2-oxoglutarate/acetoin dehydrogenase complex, dehydrogenase (E1) component	324
649661956	390	36.45	1	390	2	401	5.0e-76	278	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
649661957	85	27.63	9	84	5	79	1.0e-05	41.4	COG0236	Acyl carrier protein	80
649661961	157	47.71	49	157	38	146	6.0e-23	100	COG0071	Molecular chaperone IbpA, HSP20 family	146
649661962	228	49.77	10	222	1	213	3.0e-60	225	COG1926	Predicted phosphoribosyltransferase	220
649661965	285	32	1	145	6	154	8.0e-12	64.6	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
649661967	400	21.95	32	109	1	70	2.0e-03	37.6	COG0695	Glutaredoxin	80
649661968	911	39.69	204	834	3	596	1.0e-125	444	COG1042	Acyl-CoA synthetase (NDP forming)	598
649661975	312	34.42	10	306	1	289	1.0e-52	200	COG1013	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, beta subunit	294
649661976	412	34.77	4	371	4	359	2.0e-68	252	COG0674	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, alpha subunit	365
649661977	305	45.12	217	297	9	90	6.0e-24	105	COG1144	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit	91
649661978	102	27.71	18	100	12	94	2.0e-05	40.3	COG4980	Gas vesicle protein	115
649661980	186	25	42	137	12	96	3.0e-03	35	COG2863	Cytochrome c553	121
649661981	327	58.72	68	302	36	270	3.0e-87	315	COG2326	Polyphosphate kinase 2, PPK2 family	270
649661982	119	29.73	9	119	10	120	5.0e-11	59.9	COG2044	Predicted peroxiredoxin	120
649661985	391	28.96	3	255	4	240	2.0e-34	140	COG2041	Periplasmic DMSO/TMAO reductase YedYZ, molybdopterin-dependent catalytic subunit	271
649661986	144	24.06	1	129	2	134	2.0e-11	61.9	COG1765	Uncharacterized OsmC-related protein	137
649661987	291	46.61	57	291	25	275	2.0e-68	252	COG3258	Cytochrome c	293
649661989	116	23.48	1	115	2	101	2.0e-06	44.6	COG2863	Cytochrome c553	121
649661990	441	39.66	1	343	3	346	9.0e-66	244	COG1290	Cytochrome b subunit of the bc complex	381
649661991	183	29.81	18	168	7	164	8.0e-21	93.3	COG0723	Rieske Fe-S protein	177
649661994	121	33	10	108	4	96	3.0e-07	47.3	COG2863	Cytochrome c553	121
649661996	144	27.21	8	140	6	139	9.0e-16	76.1	COG1764	Organic hydroperoxide reductase OsmC/OhrA	143
649661997	138	32.84	1	129	19	151	3.0e-17	81.1	COG0782	Transcription elongation factor, GreA/GreB family	151
649661998	325	32.21	161	301	5	153	5.0e-14	72.3	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
649662003	573	35.04	10	571	97	709	0.0e+00	467	COG0058	Glucan phosphorylase	750
649662004	424	21.08	48	424	3	381	3.0e-19	90.1	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649662006	215	19.61	4	207	8	204	2.0e-12	65.7	COG3218	ABC-type uncharacterized transport system, auxiliary component	205
649662007	320	26.38	1	302	1	300	9.0e-26	110	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
649662008	275	55.38	17	267	7	257	8.0e-89	320	COG1127	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, ATPase component MlaF	263
649662009	373	45.49	114	368	13	262	1.0e-61	230	COG0767	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, permease component MlaE	267
649662012	141	32.86	1	140	14	153	2.0e-15	74.9	COG4244	Uncharacterized membrane protein	160
649662013	569	28.17	20	442	3	419	7.0e-30	125	COG1807	4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferase of PMT family	535
649662014	112	28.72	11	103	18	111	2.0e-09	54.6	COG0662	Mannose-6-phosphate isomerase, cupin superfamily	127
649662015	452	24.88	39	446	43	443	2.0e-36	147	COG1538	Outer membrane protein TolC	457
649662016	1110	29.19	11	1080	1	1006	0.0e+00	662	COG0841	Multidrug efflux pump subunit AcrB	1009
649662017	362	31.54	1	348	1	363	2.0e-23	103	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
649662020	267	33.73	1	254	3	252	4.0e-14	72	COG0730	Uncharacterized membrane protein YfcA	258
649662024	145	34.51	1	142	14	152	3.0e-13	68	COG4244	Uncharacterized membrane protein	160
649662025	415	21.55	1	392	3	387	2.0e-23	103	COG1252	NADH dehydrogenase, FAD-containing subunit	405
649662026	233	26.23	1	183	1	183	1.0e-14	73.8	COG5278	Extracellular (periplasmic) sensor domain CHASE3 (specificity unknown)	207
649662032	236	26.76	16	228	2	214	5.0e-30	124	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
649662033	320	29.72	9	308	8	314	9.0e-38	151	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
649662034	310	32.71	55	290	49	312	3.0e-38	152	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
649662038	467	51.51	146	467	126	457	3.0e-106	378	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
649662041	459	55.23	8	450	7	453	0.0e+00	512	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
649662042	439	24.23	49	356	12	350	3.0e-30	126	COG1566	Multidrug resistance efflux pump	352
649662043	410	29.59	20	410	2	419	3.0e-31	129	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
649662044	410	37.8	41	410	32	408	3.0e-45	176	COG0025	NhaP-type Na+/H+ or K+/H+ antiporter	429
649662049	309	55.33	20	308	12	302	5.0e-120	424	COG0320	Lipoate synthase	306
649662050	400	40.68	1	394	1	402	1.0e-86	313	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
649662051	325	59.13	3	324	2	324	0.0e+00	471	COG0022	Pyruvate/2-oxoglutarate/acetoin dehydrogenase complex, dehydrogenase (E1) component	324
649662052	325	50.31	1	324	21	344	1.0e-101	363	COG1071	TPP-dependent pyruvate or acetoin dehydrogenase subunit alpha	358
649662055	210	41.49	1	186	3	188	2.0e-47	182	COG0424	Predicted house-cleaning NTP pyrophosphatase, Maf/HAM1 superfamily	193
649662056	394	29.14	1	372	2	322	2.0e-62	232	COG0042	tRNA-dihydrouridine synthase	323
649662059	351	32.67	64	263	1	197	5.0e-36	145	COG1611	Predicted Rossmann fold nucleotide-binding protein	205
649662060	284	17.48	16	262	3	305	3.0e-09	55.8	COG2404	Oligoribonuclease NrnB or cAMP/cGMP phosphodiesterase, DHH superfamily	339
649662061	234	35.17	1	234	2	227	3.0e-28	118	COG0705	Membrane associated serine protease, rhomboid family	228
649662063	388	47.15	9	376	1	361	1.0e-119	423	COG0026	Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)	375
649662064	184	61.04	12	165	5	158	1.0e-58	219	COG0041	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase	162
649662065	532	21.28	109	429	27	273	2.0e-12	67.7	COG1566	Multidrug resistance efflux pump	352
649662067	555	24.45	23	555	148	681	3.0e-45	176	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
649662068	558	22.86	30	558	153	681	3.0e-45	176	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
649662070	236	39.43	1	231	3	248	2.0e-57	215	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
649662071	310	32.47	7	304	2	302	3.0e-43	169	COG0010	Arginase family enzyme	305
649662072	191	41.9	1	178	4	161	2.0e-40	158	COG1945	Pyruvoyl-dependent arginine decarboxylase (PvlArgDC)	163
649662073	476	42.32	7	476	3	472	7.0e-120	424	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
649662075	217	27.14	20	210	62	244	1.0e-21	96.8	COG1651	Protein-disulfide isomerase	244
649662076	367	29.11	15	359	9	314	7.0e-52	198	COG1899	Deoxyhypusine synthase	318
649662077	250	24.69	18	242	23	264	1.0e-08	53.8	COG0428	Zinc transporter ZupT	266
649662078	323	22.75	152	318	48	232	1.0e-09	57.6	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
649662081	214	42.38	5	212	2	210	1.0e-46	179	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
649662082	389	29.71	7	383	10	365	2.0e-44	173	COG4585	Signal transduction histidine kinase	365
649662084	562	30.8	4	548	2	543	9.0e-109	387	COG4626	Phage terminase-like protein, large subunit, contains N-terminal HTH domain	546
649662091	391	21.12	99	327	45	290	3.0e-06	46.4	COG4974	Site-specific recombinase XerD	300
649662100	250	44.77	4	171	5	174	1.0e-36	146	COG3740	Phage head maturation protease	194
649662104	156	31.11	6	132	1	132	5.0e-12	63.9	COG3747	Phage terminase, small subunit	160
649662108	410	21.82	83	338	31	283	2.0e-04	41	COG4974	Site-specific recombinase XerD	300
649662115	567	32.19	23	537	2	472	1.0e-99	357	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
649662117	614	38.43	5	504	2	530	4.0e-123	435	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
649662120	471	41.86	1	463	7	468	0.0e+00	477	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
649662122	232	30.34	1	231	1	230	4.0e-28	118	COG1018	Ferredoxin-NADP reductase	266
649662123	138	30.91	19	127	1	99	1.0e-13	68.9	COG0633	Ferredoxin	102
649662124	159	31.82	2	155	1	147	1.0e-27	115	COG1959	DNA-binding transcriptional regulator, IscR family	150
649662125	405	57.44	4	389	2	386	0.0e+00	529	COG1104	Cysteine sulfinate desulfinase/cysteine desulfurase or related enzyme	386
649662126	127	49.65	1	124	5	145	5.0e-35	140	COG0822	NifU homolog involved in Fe-S cluster formation	150
649662127	119	56.88	10	118	1	109	1.0e-34	138	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
649662128	192	35	1	157	1	154	1.0e-10	60	COG1076	DnaJ-domain-containing proteins 1	174
649662129	606	50.17	1	591	4	579	0.0e+00	574	COG0443	Molecular chaperone DnaK (HSP70)	579
649662130	70	56.25	3	66	1	64	7.0e-17	78.9	COG2975	Fe-S-cluster formation regulator IscX/YfhJ	64
649662131	797	42.16	28	797	12	793	0.0e+00	789	COG5009	Membrane carboxypeptidase/penicillin-binding protein	797
649662132	627	57.99	20	626	2	603	0.0e+00	823	COG1217	Predicted membrane GTPase involved in stress response	603
649662134	156	43.04	5	156	1	156	5.0e-35	140	COG1225	Peroxiredoxin	157
649662136	306	34.62	52	299	28	312	4.0e-40	158	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
649662139	250	36.79	6	111	5	97	1.0e-18	86.9	COG0720	6-pyruvoyl-tetrahydropterin synthase	127
649662141	428	28.23	18	421	3	387	1.0e-41	164	COG0247	Fe-S oxidoreductase	388
649662142	142	48.18	6	142	1	132	2.0e-35	141	COG1592	Rubrerythrin	166
649662143	154	35.71	5	143	1	140	4.0e-29	120	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
649662144	185	57.47	1	174	1	173	2.0e-59	222	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase or related enzyme	173
649662148	95	44.09	5	95	2	94	2.0e-14	70.5	COG0776	Bacterial nucleoid DNA-binding protein	94
649662163	365	41.28	56	357	39	356	7.0e-76	278	COG1858	Cytochrome c peroxidase	364
649662165	518	37.69	32	495	13	470	9.0e-110	390	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
649662166	363	26.47	1	358	1	370	3.0e-58	219	COG1748	Saccharopine dehydrogenase, NADP-dependent	389
649662167	247	35.75	18	224	2	207	3.0e-30	125	COG1774	Cell fate regulator YaaT, PSP1 superfamily (controls sporulation, competence, biofilm development)	265
649662169	161	55.13	5	160	2	155	2.0e-55	208	COG2947	Predicted RNA-binding protein, contains PUA-like domain	156
649662170	270	26.91	23	268	1	222	8.0e-17	81	COG1434	Uncharacterized SAM-binding protein YcdF, DUF218 family	223
649662173	206	24.87	6	184	7	197	3.0e-19	88.5	COG0560	Phosphoserine phosphatase	212
649662174	620	43.55	1	620	2	589	0.0e+00	544	COG0514	Superfamily II DNA helicase RecQ	590
649662177	99	36.56	1	93	1	91	7.0e-12	62.3	COG1826	Sec-independent protein translocase protein TatA	94
649662178	94	28.41	3	87	2	89	1.0e-10	58	COG1826	Sec-independent protein translocase protein TatA	94
649662182	564	21.35	12	564	130	682	3.0e-45	176	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
649662183	257	24.05	9	241	6	232	5.0e-19	88.3	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
649662185	599	32.48	25	451	8	412	3.0e-45	176	COG1807	4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferase of PMT family	535
649662186	361	23.58	28	230	23	228	7.0e-05	41.7	COG0671	Membrane-associated phospholipid phosphatase	232
649662190	304	53.07	1	304	31	339	5.0e-106	377	COG0552	Signal recognition particle GTPase	340
649662191	156	39.39	12	142	15	145	8.0e-28	116	COG0319	ssRNA-specific RNase YbeY, 16S rRNA maturation enzyme	153
649662192	353	51.83	4	326	18	345	5.0e-102	364	COG1702	Phosphate starvation-inducible protein PhoH, predicted ATPase	348
649662198	174	22.01	9	166	2	158	4.0e-08	51.1	COG4967	Tfp pilus assembly protein PilV	162
649662199	134	28.3	1	133	16	174	3.0e-07	47.7	COG4970	Tfp pilus assembly protein FimT	181
649662200	555	41.9	50	552	12	497	2.0e-128	452	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
649662203	175	20.14	6	129	2	140	1.0e-04	39.5	COG4940	Competence protein ComGF	154
649662205	259	36.76	3	254	1	252	3.0e-31	128	COG1989	Prepilin signal peptidase PulO (type II secretory pathway) or related peptidase	254
649662207	246	46.67	1	239	23	258	3.0e-60	225	COG0566	tRNA G18 (ribose-2'-O)-methylase SpoU	260
649662208	486	52.97	1	486	1	463	0.0e+00	624	COG0215	Cysteinyl-tRNA synthetase	464
649662209	236	26.4	40	232	7	203	4.0e-31	128	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
649662210	271	48.19	5	247	2	250	3.0e-80	291	COG0496	Broad specificity polyphosphatase and 5'/3'-nucleotidase SurE	252
649662212	117	25.51	13	110	1	97	9.0e-10	55.5	COG0789	DNA-binding transcriptional regulator, MerR family	124
649662213	91	42.22	1	90	2	91	1.0e-21	94.8	COG0776	Bacterial nucleoid DNA-binding protein	94
649662214	529	35.38	11	430	2	409	7.0e-99	354	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
649662215	411	46.9	1	403	1	447	2.0e-112	399	COG0527	Aspartokinase	447
649662216	416	34.73	1	371	4	366	2.0e-72	266	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase, archeal type	408
649662217	352	45.27	3	346	50	396	1.0e-100	360	COG0498	Threonine synthase	411
649662218	437	48.48	5	325	4	333	4.0e-97	348	COG0460	Homoserine dehydrogenase	333
649662219	398	41.28	11	392	5	390	3.0e-102	365	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
649662221	237	58.4	2	236	1	238	2.0e-79	288	COG0854	Pyridoxine 5'-phosphate synthase PdxJ	243
649662222	516	46.69	213	513	1	282	2.0e-62	233	COG0063	NAD(P)H-hydrate repair enzyme Nnr, NAD(P)H-hydrate dehydratase domain	284
649662223	174	43.92	1	146	3	149	1.0e-33	136	COG0802	tRNA A37 threonylcarbamoyladenosine biosynthesis protein TsaE	149
649662225	882	48.51	7	876	7	842	0.0e+00	886	COG0249	DNA mismatch repair ATPase MutS	843
649662229	417	39.18	1	407	16	431	2.0e-89	323	COG0612	Predicted Zn-dependent peptidase	438
649662230	705	61.22	1	691	3	692	0.0e+00	941	COG1185	Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase)	692
649662232	89	56.18	1	89	1	89	6.0e-25	105	COG0184	Ribosomal protein S15P/S13E	89
649662233	337	35.71	9	302	13	261	1.0e-56	213	COG0130	tRNA U55 pseudouridine synthase TruB, may also work on U342 of tmRNA	271
649662234	132	46.9	7	118	5	117	2.0e-22	98	COG0858	Ribosome-binding factor A	118
649662235	93	45.16	1	93	1	93	7.0e-21	91.8	COG1550	Uncharacterized conserved protein YlxP, DUF503 family	95
649662236	865	60.63	349	852	2	508	0.0e+00	638	COG0532	Translation initiation factor IF-2, a GTPase	509
649662237	379	52.6	156	346	1	186	5.0e-42	165	COG0195	Transcription antitermination factor NusA, contains S1 and KH domains	190
649662238	159	42.11	7	158	6	153	8.0e-37	146	COG0779	Ribosome maturation factor RimP	153
649662239	279	35.11	3	278	2	280	4.0e-51	194	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
649662241	105	40.2	1	99	2	103	2.0e-18	84.2	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
649662242	165	35.48	38	161	1	119	2.0e-18	85.7	COG1430	Uncharacterized conserved membrane protein, UPF0127 family	126
649662248	439	52.15	1	418	1	414	0.0e+00	534	COG1004	UDP-glucose 6-dehydrogenase	414
649662250	253	35.44	35	253	43	279	4.0e-20	91.9	COG1413	HEAT repeat	335
649662251	366	26.84	2	309	41	327	4.0e-11	62.6	COG1413	HEAT repeat	335
649662252	360	37.04	3	253	43	311	1.0e-19	91.1	COG1413	HEAT repeat	335
649662253	456	33.12	2	299	11	316	3.0e-17	83.4	COG1413	HEAT repeat	335
649662259	583	36.36	170	332	17	180	8.0e-28	119	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
649662260	128	40.35	14	126	16	128	9.0e-23	99.3	COG3824	Predicted Zn-dependent protease, minimal metalloprotease (MMP)-like domain	136
649662261	881	46.62	297	880	6	593	0.0e+00	595	COG0749	DNA polymerase I - 3'-5' exonuclease and polymerase domains	593
649662264	139	25.19	6	139	4	137	5.0e-12	63.7	COG2210	Peroxiredoxin family protein	137
649662265	219	40	34	218	27	211	9.0e-58	216	COG0177	Endonuclease III	211
649662267	518	51.52	1	297	1	296	1.0e-98	353	COG3643	Glutamate formiminotransferase	302
649662268	81	37.8	1	81	1	78	1.0e-12	64.9	COG0425	TusA-related sulfurtransferase	78
649662269	176	40.88	19	176	1	137	4.0e-31	127	COG2210	Peroxiredoxin family protein	137
649662270	362	23.08	18	325	25	343	1.0e-33	137	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
649662271	674	35.9	1	385	2	387	2.0e-60	227	COG0475	Kef-type K+ transport system, membrane component KefB	397
649662272	217	27.78	2	216	13	216	9.0e-22	97.1	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
649662275	340	32.36	8	340	3	314	1.0e-51	197	COG0451	Nucleoside-diphosphate-sugar epimerase	314
649662277	143	23.57	5	126	1	134	7.0e-09	53.3	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
649662278	279	30.74	24	279	34	314	9.0e-39	154	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
649662279	280	24.29	18	264	12	239	7.0e-17	81.2	COG1587	Uroporphyrinogen-III synthase	248
649662281	308	32.56	22	296	21	313	4.0e-38	151	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
649662283	203	40	8	190	2	185	3.0e-44	171	COG2353	Polyisoprenoid-binding periplasmic protein YceI	192
649662286	344	34.08	1	344	1	350	2.0e-70	259	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
649662287	396	45.62	5	389	2	388	8.0e-116	410	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
649662288	312	36.84	85	312	23	229	5.0e-51	194	COG2853	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, lipoprotein component MlaA	250
649662290	253	23.38	37	248	68	295	4.0e-14	72.1	COG1073	Fermentation-respiration switch protein FrsA, has esterase activity, DUF1100 family	299
649662296	227	43.56	1	224	6	225	4.0e-50	191	COG2013	Uncharacterized conserved protein, AIM24 family	227
649662298	278	29.92	9	246	13	255	8.0e-34	137	COG1639	HD-like signal output (HDOD) domain, no enzymatic activity	289
649662303	183	27.59	7	179	14	176	3.0e-15	74.7	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
649662306	278	33.09	9	271	9	267	5.0e-36	145	COG3769	Predicted mannosyl-3-phosphoglycerate phosphatase, HAD superfamily	274
649662331	445	44.75	11	444	2	435	1.0e-121	430	COG0305	Replicative DNA helicase	435
649662333	437	26.92	75	365	3	284	1.0e-17	84.9	COG4974	Site-specific recombinase XerD	300
649662335	239	46.29	7	233	10	237	5.0e-50	190	COG0284	Orotidine-5'-phosphate decarboxylase	240
649662336	91	48.24	5	89	4	88	1.0e-09	54.9	COG0268	Ribosomal protein S20	88
649662337	364	33.13	1	326	2	330	2.0e-46	180	COG1466	DNA polymerase III, delta subunit	334
649662339	811	49.03	1	811	1	814	0.0e+00	1007	COG0495	Leucyl-tRNA synthetase	814
649662342	228	24.34	15	226	1	226	4.0e-15	75.3	COG1011	FMN phosphatase YigB, HAD superfamily	229
649662343	464	49.2	28	464	3	438	0.0e+00	511	COG1160	Predicted GTPases	444
649662346	210	35.71	15	196	7	179	1.0e-28	119	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
649662348	157	21.85	36	152	28	137	7.0e-06	43.4	COG2010	Cytochrome c, mono- and diheme variants	150
649662352	348	41.26	1	346	1	339	3.0e-109	388	COG1064	D-arabinose 1-dehydrogenase, Zn-dependent alcohol dehydrogenase family	339
649662354	454	22.86	12	453	8	409	4.0e-37	149	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
649662356	316	43.36	18	302	1	286	1.0e-80	293	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
649662359	173	54.69	37	164	3	130	4.0e-43	167	COG3260	Ni,Fe-hydrogenase III small subunit	148
649662360	530	30.49	7	162	9	168	4.0e-17	83.1	COG0852	NADH:ubiquinone oxidoreductase 27 kD subunit (chain C)	176
649662360	530	39.12	169	530	5	367	3.0e-95	342	COG3261	Ni,Fe-hydrogenase III large subunit	382
649662361	510	29.98	4	496	10	476	1.0e-45	177	COG0651	Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit	504
649662362	221	28.97	8	220	4	217	2.0e-20	92.3	COG4237	Hydrogenase-4 membrane subunit HyfE	218
649662363	318	39.17	1	313	1	307	2.0e-46	179	COG0650	Formate hydrogenlyase subunit 4	309
649662364	675	36.09	1	505	1	485	2.0e-64	241	COG0651	Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit	504
649662370	452	50.87	1	450	1	456	0.0e+00	509	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
649662371	465	25.42	105	442	7	344	1.0e-34	141	COG3852	Signal transduction histidine kinase, nitrogen specific	363
649662372	559	22.35	31	558	154	680	6.0e-46	179	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
649662379	287	33.5	108	286	29	226	1.0e-21	97.2	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
649662380	502	29.77	60	483	8	434	5.0e-65	242	COG0612	Predicted Zn-dependent peptidase	438
649662381	523	25.5	26	514	7	436	6.0e-56	212	COG0612	Predicted Zn-dependent peptidase	438
649662382	216	31.43	7	211	4	213	2.0e-35	142	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
649662384	483	50.1	1	482	4	477	0.0e+00	524	COG0469	Pyruvate kinase	477
649662385	779	33.93	426	757	1	313	7.0e-52	199	COG0205	6-phosphofructokinase	347
649662386	154	35	39	150	35	147	2.0e-08	52.3	COG4290	Guanyl-specific ribonuclease Sa	152
649662387	178	28.4	39	119	5	80	2.0e-04	39.1	COG2732	Barstar, RNAse (barnase) inhibitor	91
649662391	427	61.68	1	427	2	429	0.0e+00	611	COG0001	Glutamate-1-semialdehyde aminotransferase	432
649662395	85	35.63	1	85	1	87	2.0e-10	57.6	COG2026	mRNA-degrading endonuclease RelE, toxin component of the RelBE toxin-antitoxin system	90
649662398	153	26.58	1	153	26	181	2.0e-16	78.5	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
649662399	147	29.31	15	129	11	124	3.0e-12	64.7	COG3187	Heat shock protein HslJ	142
649662403	251	25.73	68	251	11	215	6.0e-13	68	COG2755	Lysophospholipase L1 or related esterase	216
649662404	412	24.02	93	281	5	194	7.0e-05	42.2	COG2755	Lysophospholipase L1 or related esterase	216
649662405	133	40.48	1	125	8	131	7.0e-25	106	COG0824	Acyl-CoA thioesterase FadM	137
649662408	144	31.94	1	144	3	140	4.0e-15	73.8	COG1585	Membrane protein implicated in regulation of membrane protease activity	140
649662409	312	38.28	4	300	2	289	1.0e-45	177	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
649662410	192	51.7	1	176	1	176	5.0e-57	213	COG0279	Phosphoheptose isomerase	176
649662413	397	37.43	7	354	1	353	9.0e-65	241	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
649662415	1157	42.73	29	1142	14	1133	0.0e+00	1137	COG1197	Transcription-repair coupling factor (superfamily II helicase)	1139
649662416	304	23.16	48	294	45	316	7.0e-12	64.7	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
649662417	344	19.27	41	344	3	314	1.0e-11	64.7	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
649662418	200	46.04	1	199	2	197	3.0e-57	214	COG0218	GTP-binding protein EngB required for normal cell division	200
649662420	142	44.12	1	130	2	136	1.0e-31	128	COG3565	Predicted dioxygenase of extradiol dioxygenase family	138
649662421	312	42.86	4	309	2	306	6.0e-59	221	COG1446	Isoaspartyl peptidase or L-asparaginase, Ntn-hydrolase superfamily	307
649662423	156	61.38	1	145	1	145	2.0e-54	204	COG1490	D-Tyr-tRNAtyr deacylase	145
649662424	168	34.52	1	159	1	167	3.0e-31	127	COG0350	O6-methylguanine-DNA--protein-cysteine methyltransferase	168
649662425	542	40.5	13	524	1	515	2.0e-92	333	COG0728	Peptidoglycan biosynthesis protein MviN/MurJ, putative lipid II flippase	518
649662426	220	27.7	9	217	6	210	6.0e-17	80.8	COG3762	Uncharacterized membrane protein	213
649662427	301	33.44	5	301	1	271	2.0e-40	159	COG1512	Uncharacterized membrane protein YgcG, contains a TPM-fold domain	271
649662428	200	51.83	5	195	1	183	2.0e-55	208	COG1704	Uncharacterized conserved protein	185
649662431	257	41.92	1	255	1	259	5.0e-77	280	COG0708	Exonuclease III	261
649662437	453	34.3	2	441	10	452	9.0e-98	351	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
649662443	467	57.78	2	466	1	422	0.0e+00	618	COG0065	Homoaconitase/3-isopropylmalate dehydratase large subunit	423
649662444	206	58.13	1	203	1	191	3.0e-76	277	COG0066	3-isopropylmalate dehydratase small subunit	191
649662446	354	37.12	29	354	1	322	8.0e-74	271	COG0598	Mg2+ and Co2+ transporter CorA	322
649662447	270	36.22	1	243	1	251	4.0e-44	171	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
649662448	289	33.8	1	281	1	283	2.0e-49	189	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
649662451	384	36.68	23	384	26	390	4.0e-83	302	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
649662455	148	53.44	6	134	5	135	2.0e-38	151	COG1832	Predicted CoA-binding protein	140
649662456	207	50.3	30	194	1	165	4.0e-62	231	COG0225	Peptide methionine sulfoxide reductase MsrA	174
649662458	169	26.63	2	161	24	204	3.0e-13	68	COG1611	Predicted Rossmann fold nucleotide-binding protein	205
649662463	448	24.03	32	440	18	449	4.0e-38	152	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
649662464	487	27.73	7	481	2	454	3.0e-73	269	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
649662465	103	37.76	6	100	2	97	3.0e-11	60	COG3357	Predicted transcriptional regulator containing an HTH domain fused to a Zn-ribbon	97
649662468	264	35	5	262	13	268	3.0e-46	178	COG3752	Steroid 5-alpha reductase family enzyme	272
649662469	118	29.57	1	115	19	126	8.0e-08	49.2	COG2010	Cytochrome c, mono- and diheme variants	150
649662470	290	33.09	5	273	3	271	3.0e-52	198	COG1091	dTDP-4-dehydrorhamnose reductase	281
649662471	224	25.96	8	213	1	199	5.0e-12	64.5	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
649662473	560	45.39	9	541	3	530	0.0e+00	549	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
649662474	240	34.22	46	229	30	215	8.0e-32	130	COG2930	Lipid-binding SYLF domain	227
649662475	268	25.32	27	260	9	240	3.0e-17	82.7	COG0748	Putative heme iron utilization protein	245
649662478	237	31.63	18	232	11	202	4.0e-31	128	COG0400	Predicted esterase	207
649662480	491	49.8	6	491	5	488	0.0e+00	601	COG0397	Uncharacterized conserved protein YdiU, UPF0061 family	488
649662481	165	45.3	48	164	4	120	3.0e-25	108	COG5609	Uncharacterized protein YbcI	124
649662485	113	23.53	9	103	1	101	9.0e-07	45.5	COG0347	Nitrogen regulatory protein PII	112
649662487	133	25.81	1	122	3	125	2.0e-05	41.9	COG4113	Predicted nucleic acid-binding protein, contains PIN domain	134
649662488	80	29.87	1	75	1	77	7.0e-03	32.3	COG4691	Plasmid stability protein	80
649662490	345	24.34	94	315	10	228	1.0e-12	67.7	COG3063	Tfp pilus assembly protein PilF	250
649662492	418	44.26	1	415	3	428	4.0e-130	458	COG0124	Histidyl-tRNA synthetase	429
649662493	106	19.84	4	105	1	126	2.0e-04	37.6	COG1553	Sulfur relay (sulfurtransferase) complex TusBCD TusD component, DsrE family	126
649662494	116	23.14	6	116	3	118	7.0e-03	32.9	COG2923	Sulfur relay (sulfurtransferase) complex TusC component, DsrF/TusC family	118
