gene_oid	gene_length	percent_identity	query_start	query_end	subj_start	subj_end	evalue	bit_score	cog_id	cog_name	cog_length
641662746	510	50.29	163	506	68	408	2.0e-112	400	COG0593	Chromosomal replication initiation ATPase DnaA	408
641662747	381	37.2	4	381	3	364	6.0e-78	284	COG0592	DNA polymerase III sliding clamp (beta) subunit, PCNA homolog	364
641662748	864	60.41	40	621	3	559	0.0e+00	853	COG0187	DNA gyrase/topoisomerase IV, subunit B	635
641662750	299	24.5	2	298	1	293	4.0e-23	101	COG0583	DNA-binding transcriptional regulator, LysR family	297
641662751	104	42.86	1	104	1	105	3.0e-22	97	COG4390	Uncharacterized protein	106
641662752	400	24.46	105	336	1	232	1.0e-09	57.7	COG2202	PAS domain	232
641662753	516	36.55	27	510	87	550	4.0e-85	309	COG2989	Murein L,D-transpeptidase YcbB/YkuD	561
641662754	205	42.55	18	205	3	182	3.0e-40	158	COG3108	Uncharacterized conserved protein YcbK, DUF882 family	185
641662756	324	21.33	26	311	14	303	2.0e-09	56.6	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
641662757	249	21.43	4	241	19	256	1.0e-08	54	COG0767	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, permease component MlaE	267
641662758	363	25	14	352	9	340	7.0e-28	118	COG0628	Predicted PurR-regulated permease PerM	355
641662759	126	21.88	10	105	6	92	8.0e-06	42.7	COG1694	NTP pyrophosphatase, house-cleaning of non-canonical NTPs	102
641662760	287	29.49	1	267	1	279	1.0e-27	117	COG3491	Isopenicillin N synthase and related dioxygenases	322
641662761	922	33.75	13	328	25	306	7.0e-40	159	COG3868	Uncharacterized protein	306
641662766	507	25.35	158	507	56	379	5.0e-27	116	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
641662767	456	42.54	1	456	1	454	3.0e-103	369	COG4267	Uncharacterized membrane protein	467
641662768	303	30.69	20	295	14	289	3.0e-34	139	COG5495	Predicted oxidoreductase, contains short-chain dehydrogenase (SDR) and DUF2520 domains	289
641662769	210	38.86	3	174	14	186	4.0e-32	131	COG0847	DNA polymerase III, epsilon subunit or related 3'-5' exonuclease	243
641662770	481	38.4	9	477	2	453	1.0e-97	350	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
641662771	154	21.01	11	148	5	136	1.0e-12	65.7	COG1764	Organic hydroperoxide reductase OsmC/OhrA	143
641662772	209	55.56	1	204	1	206	1.0e-65	242	COG2808	Predicted FMN-binding regulatory protein PaiB	209
641662775	448	27.53	199	448	50	313	7.0e-26	112	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
641662777	263	36.69	14	261	2	217	2.0e-42	166	COG0850	Septum formation inhibitor MinC	219
641662778	272	63.24	1	272	1	270	1.0e-113	403	COG2894	Septum formation inhibitor-activating ATPase MinD	272
641662779	87	51.72	1	87	1	85	2.0e-21	94.1	COG0851	Septum formation topological specificity factor MinE	88
641662782	409	39.39	18	408	6	396	4.0e-96	345	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
641662783	327	33.97	11	324	5	317	3.0e-57	215	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
641662784	423	34.76	14	419	2	391	2.0e-60	227	COG0183	Acetyl-CoA acetyltransferase	392
641662785	404	25.67	5	335	4	300	2.0e-45	176	COG0205	6-phosphofructokinase	347
641662786	182	43.11	14	178	7	172	3.0e-40	157	COG3040	Bacterial lipocalin	174
641662787	543	58	113	262	7	152	6.0e-44	172	COG5616	TolB amino-terminal domain (function unknown)	152
641662789	382	26.11	154	378	7	215	9.0e-23	101	COG2114	Adenylate cyclase, class 3	227
641662791	508	37.76	170	507	14	334	2.0e-42	166	COG0642	Signal transduction histidine kinase	336
641662792	208	31.37	10	208	12	206	3.0e-30	125	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
641662793	337	28.03	18	297	6	290	2.0e-27	116	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
641662794	380	30.6	26	363	12	368	2.0e-45	176	COG2021	Homoserine acetyltransferase	368
641662795	386	30.08	38	375	12	368	3.0e-41	162	COG2021	Homoserine acetyltransferase	368
641662804	333	28.05	15	328	8	330	1.0e-38	153	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
641662805	349	28.68	52	177	28	156	3.0e-18	86.2	COG2143	Thioredoxin-related protein	182
641662811	756	27.29	64	756	31	728	1.0e-77	284	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
641662812	167	50.33	1	148	3	152	3.0e-50	191	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
641662813	603	24	97	595	29	450	3.0e-30	127	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
641662814	198	22.56	6	194	10	201	8.0e-16	77	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
641662815	199	21.99	7	196	3	176	5.0e-12	64.5	COG2059	Chromate transport protein ChrA	195
641662816	233	30.18	23	188	6	172	2.0e-22	99.1	COG2059	Chromate transport protein ChrA	195
641662817	307	26.8	1	274	2	285	1.0e-33	136	COG0331	Malonyl CoA-acyl carrier protein transacylase	310
641662818	295	37.27	27	285	7	277	5.0e-34	138	COG1767	Triphosphoribosyl-dephospho-CoA synthetase	288
641662824	343	41.72	30	342	9	319	2.0e-70	259	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
641662825	240	42.52	4	216	18	230	1.0e-32	133	COG1802	DNA-binding transcriptional regulator, GntR family	230
641662826	428	41.48	38	419	5	390	3.0e-104	372	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
641662827	223	34.83	9	208	4	203	2.0e-33	136	COG3917	2-hydroxychromene-2-carboxylate isomerase	203
641662830	427	30.98	34	427	5	368	2.0e-54	206	COG3616	D-serine deaminase, pyridoxal phosphate-dependent	368
641662831	690	42.22	9	683	2	605	0.0e+00	537	COG3284	Transcriptional regulator of acetoin/glycerol metabolism	606
641662832	153	34.74	49	140	10	104	9.0e-14	69.6	COG0607	Rhodanese-related sulfurtransferase	110
641662833	602	30.11	160	593	1	442	6.0e-80	291	COG2072	Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD	443
641662834	210	28.57	13	194	7	176	1.0e-26	113	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
641662835	215	27.13	10	192	26	207	5.0e-20	91.2	COG3148	Uncharacterized conserved protein YfiP, DTW domain	231
641662836	248	31.84	8	247	5	236	5.0e-34	138	COG0412	Dienelactone hydrolase	236
641662837	347	40.25	13	332	1	310	1.0e-74	273	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
641662838	190	51.61	1	186	1	185	3.0e-41	161	COG2119	Putative Ca2+/H+ antiporter, TMEM165/GDT1 family	190
641662839	620	49.68	1	620	1	597	0.0e+00	760	COG0449	Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains	597
641662840	168	38.78	3	149	2	147	1.0e-27	116	COG1522	DNA-binding transcriptional regulator, Lrp family	154
641662842	469	53.94	1	465	1	460	0.0e+00	582	COG1207	Bifunctional protein GlmU, N-acetylglucosamine-1-phosphate-uridyltransferase/glucosamine-1-phosphate-acetyltransferase	460
641662845	326	33.6	33	279	1	243	2.0e-51	196	COG0037	tRNA(Ile)-lysidine synthase TilS/MesJ	298
641662846	132	26.05	13	130	2	119	2.0e-19	88.3	COG1539	Dihydroneopterin aldolase	121
641662847	270	34.15	21	253	9	250	9.0e-27	114	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
641662848	404	37.5	40	398	3	370	1.0e-71	263	COG1565	SAM-dependent methyltransferase, MidA family	370
641662850	419	35.11	1	370	23	386	1.0e-69	257	COG0617	tRNA nucleotidyltransferase/poly(A) polymerase	412
641662851	241	30	10	226	7	208	2.0e-22	99.9	COG0625	Glutathione S-transferase	211
641662852	465	43.16	1	459	3	460	1.0e-114	406	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
641662854	321	38.85	3	262	2	244	1.0e-20	94.2	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
641662855	690	34.86	390	661	7	289	3.0e-23	104	COG0741	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)	296
641662856	320	26.75	8	314	1	297	1.0e-24	107	COG0583	DNA-binding transcriptional regulator, LysR family	297
641662858	134	37.07	1	116	3	116	6.0e-20	90	COG3070	Transcriptional regulator of competence genes, TfoX/Sxy family	121
641662859	196	33.87	11	189	3	186	2.0e-32	132	COG0212	5-formyltetrahydrofolate cyclo-ligase	191
641662860	198	38.97	1	198	1	213	8.0e-41	160	COG3047	Outer membrane protein W	213
641662861	279	39.93	6	279	14	289	6.0e-66	244	COG0685	5,10-methylenetetrahydrofolate reductase	291
641662862	302	40.96	45	293	3	241	3.0e-62	232	COG1189	Predicted rRNA methylase YqxC, contains S4 and FtsJ domains	245
641662863	477	55.97	12	469	4	420	0.0e+00	619	COG0499	S-adenosylhomocysteine hydrolase	420
641662864	191	37.36	19	191	45	217	7.0e-30	123	COG3485	Protocatechuate 3,4-dioxygenase beta subunit	226
641662866	405	60.74	1	404	1	394	0.0e+00	547	COG0027	Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase)	394
641662869	360	27.49	1	360	3	380	6.0e-37	148	COG3214	Uncharacterized conserved protein YcaQ, contains winged helix DNA-binding domain	400
641662870	393	67.77	1	393	1	388	0.0e+00	653	COG0192	S-adenosylmethionine synthetase	388
641662871	289	34.4	6	278	41	304	7.0e-47	180	COG1560	Lauroyl/myristoyl acyltransferase	308
641662872	294	44.1	9	294	21	307	2.0e-69	256	COG1560	Lauroyl/myristoyl acyltransferase	308
641662873	297	46.37	3	291	1	272	2.0e-78	286	COG0253	Diaminopimelate epimerase	272
641662874	226	31.65	6	221	4	216	1.0e-32	133	COG3159	Uncharacterized conserved protein YigA, DUF484 family	218
641662875	312	50.17	14	311	12	299	1.0e-83	303	COG4973	Site-specific recombinase XerC	299
641662876	496	46.18	1	490	5	502	8.0e-120	424	COG1070	Sugar (pentulose or hexulose) kinase	502
641662877	315	30.08	187	309	3	125	2.0e-22	99	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
641662878	465	35	6	460	15	464	4.0e-105	375	COG0246	Mannitol-1-phosphate/altronate dehydrogenases	473
641662879	350	55.26	1	338	1	338	4.0e-122	431	COG3839	ABC-type sugar transport system, ATPase component	338
641662880	276	36.3	1	276	1	281	3.0e-46	178	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
641662881	290	35.19	7	290	9	293	2.0e-45	175	COG1175	ABC-type sugar transport system, permease component	295
641662882	434	23.91	1	429	12	432	5.0e-36	145	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
641662883	397	43.91	4	392	1	388	3.0e-92	332	COG1092	23S rRNA G2069 N7-methylase RlmK or C1962 C5-methylase RlmI	393
641662887	368	21.28	41	361	21	356	1.0e-06	48.2	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
641662888	1047	38.68	1	1025	1	1022	0.0e+00	842	COG3696	Cu/Ag efflux pump CusA	1027
641662892	730	44.76	30	726	42	711	0.0e+00	663	COG2217	Cation transport ATPase	713
641662894	172	37.32	32	171	1	141	1.0e-16	79.9	COG3193	Uncharacterized conserved protein GlcG, DUF336 family	141
641662897	351	32.73	21	348	2	307	3.0e-57	215	COG1893	Ketopantoate reductase	307
641662898	447	26.4	1	439	7	423	3.0e-67	249	COG2072	Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD	443
641662899	790	31.92	163	408	9	263	2.0e-50	194	COG3665	Uncharacterized conserved protein YcgI, DUF1989 family	264
641662899	790	37.21	411	790	5	379	3.0e-91	329	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
641662900	112	69.64	1	112	1	112	1.0e-36	144	COG0347	Nitrogen regulatory protein PII	112
641662901	447	53.3	42	447	1	404	1.0e-108	386	COG0004	Ammonia channel protein AmtB	409
641662902	569	33.41	20	478	2	396	6.0e-72	265	COG0644	Dehydrogenase (flavoprotein)	396
641662903	270	48.68	5	267	6	270	4.0e-77	281	COG3741	N-formylglutamate amidohydrolase	272
641662904	343	30.43	21	318	1	294	6.0e-26	111	COG0583	DNA-binding transcriptional regulator, LysR family	297
641662905	394	30.53	1	384	2	387	2.0e-45	177	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
641662906	253	42.75	1	245	1	255	1.0e-51	196	COG2086	Electron transfer flavoprotein, alpha and beta subunits	260
641662907	317	45.08	1	310	1	310	4.0e-71	261	COG2025	Electron transfer flavoprotein, alpha subunit	313
641662908	201	28.8	22	201	16	193	7.0e-19	87.3	COG3758	Various environmental stresses-induced protein Ves (function unknown)	193
641662910	464	40.22	24	462	2	442	5.0e-114	405	COG0174	Glutamine synthetase	443
641662911	302	21.27	1	300	12	366	5.0e-31	128	COG0067	Glutamate synthase domain 1	371
641662913	456	35.06	38	436	87	485	2.0e-97	349	COG0069	Glutamate synthase domain 2	485
641662915	316	31.68	7	255	7	266	1.0e-40	160	COG1018	Ferredoxin-NADP reductase	266
641662917	376	35.84	1	372	2	377	1.0e-82	300	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
641662918	287	56.45	1	287	1	287	3.0e-122	431	COG0788	Formyltetrahydrofolate hydrolase	287
641662919	301	59.79	4	283	1	281	3.0e-104	371	COG0190	5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase	283
641662920	776	45.72	12	746	4	754	0.0e+00	773	COG5009	Membrane carboxypeptidase/penicillin-binding protein	797
641662921	121	36.84	9	121	1	105	8.0e-16	75.8	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
641662922	844	50	1	806	4	793	0.0e+00	1025	COG1251	NAD(P)H-nitrite reductase, large subunit	793
641662924	133	35.05	4	98	2	97	2.0e-20	91.9	COG2154	Pterin-4a-carbinolamine dehydratase	101
641662925	665	22.89	420	664	3	222	1.0e-10	62.2	COG0569	Trk K+ transport system, NAD-binding component	225
641662925	665	38.65	1	398	4	395	1.0e-58	221	COG0475	Kef-type K+ transport system, membrane component KefB	397
641662926	330	55.45	13	213	1	202	2.0e-63	236	COG0794	D-arabinose 5-phosphate isomerase GutQ	202
641662927	203	44.58	26	191	1	166	2.0e-48	185	COG1778	 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsC and related HAD superfamily phosphatases	170
641662928	231	20.22	44	221	10	182	2.0e-11	63	COG3117	Lipopolysaccharide export system protein LptC	188
641662929	267	28.2	7	265	1	265	7.0e-38	151	COG0300	Short-chain dehydrogenase	265
641662931	213	38.65	1	207	5	203	4.0e-33	134	COG2095	Small neutral amino acid transporter SnatA, MarC family	203
641662932	552	44.04	1	550	5	537	0.0e+00	486	COG2303	Choline dehydrogenase or related flavoprotein	542
641662933	253	27.84	1	253	4	257	1.0e-12	67.3	COG0730	Uncharacterized membrane protein YfcA	258
641662934	258	21.64	1	228	2	259	1.0e-16	80.1	COG1234	Ribonuclease BN, tRNA processing enzyme	292
641662936	268	36.47	4	264	1	262	1.0e-54	207	COG0631	Serine/threonine protein phosphatase PrpC	262
641662937	314	28.37	1	267	13	294	2.0e-35	142	COG0515	Serine/threonine protein kinase	384
641662938	247	26.91	1	204	8	224	8.0e-31	127	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
641662940	315	31.01	3	315	1	342	3.0e-70	259	COG0002	N-acetyl-gamma-glutamylphosphate reductase	349
641662941	204	49.16	25	201	4	180	3.0e-41	161	COG3545	Predicted esterase of the alpha/beta hydrolase fold	181
641662942	302	41.53	37	270	7	226	3.0e-28	119	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
641662943	640	67.8	1	640	1	649	0.0e+00	855	COG2766	Predicted Ser/Thr protein kinase	649
641662944	428	50.47	1	424	1	418	0.0e+00	461	COG2718	Uncharacterized conserved protein YeaH/YhbH, required for sporulation, DUF444 family	423
641662945	532	63.11	41	528	8	488	0.0e+00	656	COG2719	Stage V sporulation protein SpoVR/YcgB, involved in spore cortex formation (function unknown)	495
641662946	473	42.54	31	473	8	458	2.0e-91	329	COG0277	FAD/FMN-containing dehydrogenase	459
641662947	247	25.49	42	232	12	213	1.0e-23	103	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
641662949	268	34.2	11	238	1	230	2.0e-31	129	COG1802	DNA-binding transcriptional regulator, GntR family	230
641662950	294	29.21	6	294	3	267	4.0e-34	138	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
641662951	298	37.76	14	296	9	282	3.0e-47	182	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
641662952	435	21.02	21	369	6	320	8.0e-23	101	COG0687	Spermidine/putrescine-binding periplasmic protein	363
641662953	333	44.1	7	333	6	352	6.0e-93	334	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
641662954	247	47.86	1	233	1	230	3.0e-52	198	COG4126	Asp/Glu/hydantoin racemase	230
641662955	671	27.07	139	402	1	232	6.0e-11	63.1	COG2202	PAS domain	232
641662955	671	35.96	393	658	83	335	8.0e-35	142	COG0642	Signal transduction histidine kinase	336
641662956	321	30.74	83	313	15	214	2.0e-36	146	COG1451	Predicted metal-dependent hydrolase	223
641662957	254	27.82	8	251	1	237	2.0e-26	112	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
641662958	199	43.62	6	154	4	152	8.0e-46	176	COG0241	Histidinol phosphatase or a related phosphatase	181
641662959	713	46.22	1	712	1	690	0.0e+00	702	COG0751	Glycyl-tRNA synthetase, beta subunit	691
641662960	317	73.88	1	287	4	294	0.0e+00	530	COG0752	Glycyl-tRNA synthetase, alpha subunit	298
641662963	191	21.97	9	180	13	182	3.0e-08	51.9	COG3945	Hemerythrin-like domain	189
641662964	681	57.86	4	680	1	663	0.0e+00	956	COG0021	Transketolase	663
641662965	332	62.46	2	332	1	332	0.0e+00	465	COG0057	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase	335
641662968	1133	29.62	6	1124	5	1093	0.0e+00	915	COG4913	Uncharacterized protein YPO0396	1104
641662969	404	25.13	4	395	1	380	2.0e-70	259	COG4924	Uncharacterized protein	386
641662971	262	39.67	29	260	1	236	5.0e-44	171	COG0340	Biotin-(acetyl-CoA carboxylase) ligase	238
641662973	876	29.82	3	652	1	570	6.0e-124	438	COG0550	DNA topoisomerase IA	570
641662975	318	30.09	1	318	1	308	1.0e-23	104	COG0679	Predicted permease	311
641662976	163	24.17	18	134	2	120	9.0e-09	53.4	COG1569	Predicted nucleic acid-binding protein, contains PIN domain	142
641662977	557	21.58	11	335	1	295	3.0e-08	54.1	COG2814	Predicted arabinose efflux permease, MFS family	394
641662980	935	25.2	1	479	2	461	1.0e-50	195	COG0591	Na+/proline symporter	493
641662983	221	33.55	18	167	5	155	7.0e-18	84.1	COG2606	Cys-tRNA(Pro) deacylase, prolyl-tRNA editing enzyme YbaK/EbsC	155
641662983	221	50	166	221	1	55	4.0e-10	58.5	COG3313	Predicted Fe-S protein YdhL, DUF1289 family	74
641662984	563	23.27	10	327	5	289	6.0e-10	59.4	COG2814	Predicted arabinose efflux permease, MFS family	394
641662986	211	50.94	2	211	1	211	4.0e-48	184	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
641662989	304	20.33	1	303	4	267	7.0e-15	75.1	COG1235	Phosphoribosyl 1,2-cyclic phosphodiesterase	269
641662990	259	37.83	28	255	5	229	3.0e-54	205	COG5424	Pyrroloquinoline quinone (PQQ) biosynthesis protein C	242
641662992	386	28.65	16	348	17	346	6.0e-43	168	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
641662993	147	29.53	1	147	4	151	3.0e-13	68.1	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
641662994	128	68.81	19	127	4	111	3.0e-30	123	COG5605	Cytochrome c oxidase subunit IV	115
641662995	248	36.62	36	248	11	206	2.0e-39	156	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
641662996	222	25	14	208	12	203	2.0e-21	95.7	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
641662997	588	46.62	19	578	7	550	0.0e+00	524	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
641662998	269	24.63	1	265	1	230	2.0e-41	163	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
641663000	159	27.52	1	148	1	148	6.0e-19	86.8	COG2606	Cys-tRNA(Pro) deacylase, prolyl-tRNA editing enzyme YbaK/EbsC	155
641663001	257	29.92	3	257	18	281	5.0e-27	114	COG5473	Uncharacterized membrane protein	290
641663002	187	47.87	1	184	2	188	7.0e-61	226	COG0450	Alkyl hydroperoxide reductase subunit AhpC (peroxiredoxin)	194
641663003	527	73.9	1	521	1	519	0.0e+00	826	COG3634	Alkyl hydroperoxide reductase subunit AhpF	520
641663004	302	28.04	7	297	6	295	1.0e-32	133	COG0583	DNA-binding transcriptional regulator, LysR family	297
641663005	213	39.91	1	213	6	216	4.0e-48	184	COG2761	Predicted dithiol-disulfide isomerase, DsbA family	225
641663008	578	40.73	13	578	11	555	9.0e-119	420	COG3975	Predicted metalloprotease, contains C-terminal PDZ domain	558
641663010	265	47.89	2	259	1	255	9.0e-59	220	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
641663011	235	20.99	1	235	9	243	9.0e-17	80.6	COG1651	Protein-disulfide isomerase	244
641663012	379	32.57	10	377	1	383	8.0e-47	181	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
641663014	290	38.32	14	285	3	260	2.0e-41	162	COG3217	Uncharacterized conserved protein YcbX, contains MOSC and Fe-S domains	270
641663015	364	60.48	1	364	1	372	0.0e+00	508	COG0012	Ribosome-binding ATPase YchF, GTP1/OBG family	372
641663017	328	25.8	1	306	10	319	5.0e-27	115	COG1305	Transglutaminase-like enzyme, putative cysteine protease	319
641663018	509	47.33	129	406	64	342	1.0e-60	227	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
641663019	442	34.12	103	440	2	335	2.0e-38	154	COG0642	Signal transduction histidine kinase	336
641663021	235	44.81	1	231	1	229	3.0e-53	201	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
641663022	141	35.21	1	139	6	147	9.0e-22	95.9	COG1522	DNA-binding transcriptional regulator, Lrp family	154
641663023	349	38.18	1	322	3	329	2.0e-75	276	COG2423	Ornithine cyclodeaminase/archaeal alanine dehydrogenase, mu-crystallin family	330
641663024	379	27.58	1	378	6	366	1.0e-23	104	COG3490	Uncharacterized protein	366
641663025	723	65.79	5	722	13	730	0.0e+00	1128	COG0376	Catalase (peroxidase I)	730
641663026	448	29.48	53	392	1	344	1.0e-40	161	COG2206	HD-GYP domain, c-di-GMP phosphodiesterase class II (or its inactivated variant)	344
641663030	334	31.86	15	331	4	317	2.0e-43	169	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
641663031	162	26.76	15	156	4	127	2.0e-11	62.2	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
641663032	514	55.36	13	513	6	501	0.0e+00	684	COG1190	Lysyl-tRNA synthetase (class II)	502
641663033	352	27.46	10	350	2	342	1.0e-45	177	COG0673	Predicted dehydrogenase	342
641663037	382	44.33	1	369	1	371	3.0e-105	375	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
641663038	426	22.22	9	404	4	407	1.0e-14	75.1	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
641663040	365	21.09	78	365	71	381	6.0e-15	75.4	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
641663041	416	24.34	111	409	87	372	1.0e-17	84.7	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
641663043	392	46.15	1	390	1	371	5.0e-115	408	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
641663044	201	37.19	1	198	39	222	1.0e-44	173	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
641663045	623	39.93	22	623	3	583	0.0e+00	532	COG1086	NDP-sugar epimerase, includes UDP-GlcNAc-inverting 4,6-dehydratase FlaA1 and capsular polysaccharide biosynthesis protein EpsC	588
641663046	302	34.56	26	292	3	300	1.0e-46	180	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
641663047	989	62.66	34	989	3	935	0.0e+00	1509	COG0178	Excinuclease UvrABC ATPase subunit	935
641663054	299	41.7	20	299	5	276	6.0e-65	241	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
641663055	209	46.57	1	201	2	201	2.0e-54	205	COG1182	FMN-dependent NADH-azoreductase	202
641663056	322	30	1	286	7	288	6.0e-28	118	COG0583	DNA-binding transcriptional regulator, LysR family	297
641663059	202	35.1	1	198	1	205	9.0e-32	129	COG0625	Glutathione S-transferase	211
641663060	126	33.65	25	120	3	101	9.0e-14	69.1	COG0278	Glutaredoxin-related protein	105
641663062	425	26.02	212	405	19	192	2.0e-25	110	COG0807	GTP cyclohydrolase II	193
641663064	211	57.49	6	211	4	210	2.0e-77	281	COG0035	Uracil phosphoribosyltransferase	210
641663066	533	29.8	375	524	23	173	1.0e-13	72.1	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
641663067	429	33.09	20	421	23	415	3.0e-65	242	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
641663068	206	30.62	1	204	1	204	2.0e-29	122	COG0625	Glutathione S-transferase	211
641663070	377	51.36	3	370	10	367	2.0e-122	432	COG2021	Homoserine acetyltransferase	368
641663073	497	20.71	20	493	8	403	4.0e-21	96.4	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
641663074	361	28.49	1	357	2	308	5.0e-25	108	COG0679	Predicted permease	311
641663075	334	40.72	3	333	2	332	1.0e-84	306	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
641663076	167	50	8	162	1	158	8.0e-49	186	COG3265	Gluconate kinase	161
641663077	341	37.58	14	341	1	329	2.0e-72	266	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
641663078	463	49.29	178	459	1	262	1.0e-88	320	COG1760	L-serine deaminase	262
641663081	756	35.48	13	729	6	712	0.0e+00	506	COG0643	Chemotaxis protein histidine kinase CheA	716
641663082	720	36.91	348	671	45	407	2.0e-43	171	COG0840	Methyl-accepting chemotaxis protein	408
641663083	169	36.99	14	159	19	160	1.0e-28	119	COG0835	Chemotaxis signal transduction protein	165
641663084	280	39.78	13	279	1	268	2.0e-60	225	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
641663085	185	27.66	29	163	7	143	5.0e-17	81.1	COG1871	Chemotaxis receptor (MCP) glutamine deamidase CheD	164
641663086	356	46.72	3	352	1	342	1.0e-90	327	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
641663087	192	39.07	1	187	1	215	1.0e-23	103	COG4094	Uncharacterized membrane protein	219
641663088	687	40.86	6	671	1	655	0.0e+00	509	COG0210	Superfamily I DNA or RNA helicase	655
641663089	624	32.49	174	552	135	490	7.0e-13	69.6	COG1404	Serine protease, subtilisin family	508
641663091	684	50	363	622	1	253	3.0e-69	257	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
641663092	127	45.26	33	127	1	95	4.0e-25	106	COG1862	Preprotein translocase subunit YajC	97
641663093	633	47.74	76	604	2	501	2.0e-130	459	COG0342	Preprotein translocase subunit SecD	506
641663094	344	43.37	1	332	1	303	1.0e-78	287	COG0341	Preprotein translocase subunit SecF	305
641663096	150	38.22	1	150	1	157	1.0e-28	118	COG2922	Uncharacterized conserved protein Smg, DUF494 family	157
641663097	379	42.02	1	376	1	350	5.0e-87	314	COG0758	Predicted Rossmann fold nucleotide-binding protein DprA/Smf involved in DNA uptake	350
641663099	171	51.79	1	165	1	168	4.0e-56	210	COG0242	Peptide deformylase	168
641663100	322	50.79	3	319	1	307	5.0e-98	351	COG0223	Methionyl-tRNA formyltransferase	307
641663102	259	28.07	20	244	12	237	4.0e-26	111	COG1296	Predicted branched-chain amino acid permease (azaleucine resistance)	238
641663103	109	33.67	8	105	8	105	3.0e-08	50.6	COG4392	Branched-chain amino acid transport protein	107
641663104	397	49.39	1	396	2	395	2.0e-124	439	COG0126	3-phosphoglycerate kinase	395
641663106	101	46.25	19	98	20	97	4.0e-17	79.5	COG1669	Predicted nucleotidyltransferase	97
641663107	112	32.14	1	112	2	113	5.0e-23	99.6	COG2361	Uncharacterized conserved protein, contains HEPN domain	117
641663108	769	41.03	439	765	1	325	3.0e-92	333	COG0280	Phosphotransacetylase	327
641663108	769	53.2	7	442	13	432	0.0e+00	557	COG0281	Malic enzyme	432
641663109	476	49.79	1	475	3	477	0.0e+00	530	COG0469	Pyruvate kinase	477
641663110	354	46.06	1	329	1	286	8.0e-97	347	COG0191	Fructose/tagatose bisphosphate aldolase	286
641663111	302	32.42	13	302	4	247	6.0e-63	234	COG0152	Phosphoribosylaminoimidazole-succinocarboxamide synthase	247
641663113	312	37.38	1	312	25	304	1.0e-53	203	COG3118	Negative regulator of GroEL, contains thioredoxin-like and TPR-like domains	304
641663114	164	65.38	5	160	2	155	5.0e-55	207	COG0041	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase	162
641663115	406	45.24	25	400	2	367	8.0e-111	394	COG0026	Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)	375
641663116	346	40.74	3	217	2	211	6.0e-53	201	COG0009	tRNA A37 threonylcarbamoyladenosine synthetase subunit TsaC/SUA5/YrdC	211
641663118	474	29.66	30	465	20	462	3.0e-64	239	COG2027	D-alanyl-D-alanine carboxypeptidase	470
641663119	248	32.47	5	232	2	218	4.0e-26	111	COG1214	tRNA A37 threonylcarbamoyladenosine modification protein TsaB	220
641663120	168	29.81	13	155	13	173	2.0e-16	78.5	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
641663121	294	44.9	107	290	9	199	1.0e-40	160	COG1573	Uracil-DNA glycosylase	202
641663122	360	23.91	60	356	60	322	8.0e-36	144	COG0598	Mg2+ and Co2+ transporter CorA	322
641663123	335	58.84	7	334	5	330	0.0e+00	501	COG0113	Delta-aminolevulinic acid dehydratase, porphobilinogen synthase	330
641663125	455	56.61	1	452	1	451	0.0e+00	565	COG0541	Signal recognition particle GTPase	451
641663126	255	36.07	7	246	26	265	3.0e-28	118	COG4137	ABC-type uncharacterized transport system, permease component	265
641663128	694	27.8	418	685	71	334	1.0e-27	118	COG0642	Signal transduction histidine kinase	336
641663129	522	43.25	4	507	2	459	6.0e-127	448	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
641663130	209	45.83	13	197	2	188	3.0e-47	181	COG3023	N-acetyl-anhydromuramyl-L-alanine amidase AmpD	257
641663131	958	36.9	183	917	1	652	0.0e+00	585	COG0209	Ribonucleotide reductase alpha subunit	696
641663132	402	39.58	66	400	10	339	5.0e-101	361	COG0208	Ribonucleotide reductase beta subunit, ferritin-like domain	348
641663133	125	39.56	30	117	10	100	1.0e-14	71.9	COG1872	Uncharacterized conserved protein YggU, UPF0235/DUF167 family	102
641663135	302	26.92	2	300	1	303	2.0e-36	146	COG0524	Sugar or nucleoside kinase, ribokinase family	311
641663138	252	45.85	1	249	1	246	6.0e-67	247	COG0121	Predicted glutamine amidotransferase	252
641663139	425	26.47	25	360	3	321	1.0e-33	137	COG0644	Dehydrogenase (flavoprotein)	396
641663140	790	35.38	60	370	8	304	9.0e-44	172	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
641663141	330	39.34	1	327	3	328	2.0e-68	253	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
641663142	265	43.28	24	224	5	195	9.0e-52	197	COG0218	GTP-binding protein EngB required for normal cell division	200
641663143	209	44	8	132	5	121	1.0e-20	93.5	COG2863	Cytochrome c553	121
641663145	334	45.04	30	306	5	271	8.0e-61	227	COG2041	Periplasmic DMSO/TMAO reductase YedYZ, molybdopterin-dependent catalytic subunit	271
641663146	241	42.16	39	240	8	208	2.0e-33	136	COG2717	Periplasmic DMSO/TMAO reductase YedYZ, heme-binding membrane subunit	209
641663148	254	26.67	10	248	29	283	1.0e-15	76.6	COG0790	TPR repeat	292
641663149	222	46.19	1	222	11	212	3.0e-64	238	COG0321	Lipoate-protein ligase B	221
641663150	331	61.31	22	324	1	303	0.0e+00	480	COG0320	Lipoate synthase	306
641663152	305	30.87	5	297	1	297	1.0e-29	123	COG0583	DNA-binding transcriptional regulator, LysR family	297
641663153	249	40.7	1	247	1	251	8.0e-42	163	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
641663154	330	41.77	3	329	2	328	5.0e-87	314	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
641663155	176	25	1	172	5	176	5.0e-16	77.3	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
641663156	419	44.24	46	418	1	372	2.0e-83	302	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
641663157	294	20.74	17	264	6	265	5.0e-15	75.3	COG1082	Sugar phosphate isomerase/epimerase	274
641663158	339	40.84	24	333	12	321	4.0e-76	278	COG2390	DNA-binding transcriptional regulator LsrR, DeoR family	321
641663159	149	47.68	1	148	1	151	4.0e-40	157	COG0698	Ribose 5-phosphate isomerase RpiB	151
641663160	588	45.12	3	329	1	321	2.0e-82	300	COG2376	Dihydroxyacetone kinase	323
641663161	1053	24.36	705	1053	3	238	8.0e-29	123	COG0176	Transaldolase	239
641663161	1053	58.99	1	688	1	662	0.0e+00	980	COG0021	Transketolase	663
641663162	227	24.73	19	199	1	182	5.0e-10	58.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
641663163	186	37.65	1	170	5	174	1.0e-26	112	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
641663164	426	50.79	47	424	1	378	1.0e-96	347	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
641663165	331	41.99	1	325	2	332	1.0e-86	313	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
641663166	149	51.02	1	147	1	146	5.0e-49	186	COG0757	3-dehydroquinate dehydratase	146
641663167	635	27.64	1	265	3	272	2.0e-33	137	COG1082	Sugar phosphate isomerase/epimerase	274
641663167	635	38.42	269	630	1	355	9.0e-83	301	COG3185	4-hydroxyphenylpyruvate dioxygenase and related hemolysins	363
641663168	278	31.9	3	275	2	279	6.0e-46	177	COG0169	Shikimate 5-dehydrogenase	283
641663170	298	36.67	8	276	14	271	4.0e-51	195	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
641663171	258	37.24	6	242	7	228	3.0e-39	155	COG0775	Nucleoside phosphorylase	234
641663173	561	38.52	13	556	1	524	0.0e+00	469	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
641663174	474	74	1	473	1	463	0.0e+00	641	COG1282	NAD/NADP transhydrogenase beta subunit	463
641663176	380	51.47	3	376	2	356	4.0e-106	378	COG3288	NAD/NADP transhydrogenase alpha subunit	356
641663177	166	29.05	1	147	2	143	1.0e-06	46.6	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
641663178	380	22.73	19	354	6	331	1.0e-19	91.3	COG0859	ADP-heptose:LPS heptosyltransferase	334
641663180	380	53.66	6	374	1	353	3.0e-128	451	COG0482	tRNA U34 2-thiouridine synthase MnmA/TrmU, contains the PP-loop ATPase domain	356
641663181	434	20.54	91	383	28	259	3.0e-23	103	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
641663182	179	24.46	5	136	2	138	9.0e-10	56.8	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
641663183	358	55.46	1	355	10	359	7.0e-116	410	COG3185	4-hydroxyphenylpyruvate dioxygenase and related hemolysins	363
641663184	174	52.87	1	174	2	175	8.0e-54	203	COG0663	Carbonic anhydrase or acetyltransferase, isoleucine patch superfamily	176
641663185	337	36.45	15	334	1	317	9.0e-59	220	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
641663186	392	42.82	8	385	3	380	7.0e-98	351	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
641663188	318	29.14	4	304	1	297	1.0e-28	120	COG0583	DNA-binding transcriptional regulator, LysR family	297
641663189	267	35.25	26	267	2	244	1.0e-40	160	COG1414	DNA-binding transcriptional regulator, IclR family	246
641663190	399	25.44	4	394	1	387	3.0e-53	202	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
641663191	584	33.1	1	561	7	553	6.0e-87	315	COG0659	Sulfate permease or related transporter, MFS superfamily	554
641663192	293	28.14	73	264	15	187	7.0e-11	61.5	COG2945	Alpha/beta superfamily hydrolase	210
641663193	140	22.46	1	138	3	130	2.0e-18	84.5	COG0824	Acyl-CoA thioesterase FadM	137
641663195	455	26.97	3	445	13	455	6.0e-44	171	COG0534	Na+-driven multidrug efflux pump	455
641663198	276	35.94	40	251	47	263	9.0e-22	97.4	COG0790	TPR repeat	292
641663199	456	45.98	14	185	1	174	6.0e-35	142	COG2059	Chromate transport protein ChrA	195
641663200	350	31.43	9	285	5	284	2.0e-15	76.8	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
641663201	172	42.31	16	171	11	166	2.0e-43	168	COG4702	Uncharacterized protein, UPF0303 family	168
641663202	412	34.58	8	407	5	381	4.0e-81	295	COG2942	Mannose or cellobiose epimerase, N-acyl-D-glucosamine 2-epimerase family	388
641663203	339	39.76	3	324	1	330	1.0e-62	234	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
641663206	189	41.88	1	189	1	191	2.0e-40	158	COG2353	Polyisoprenoid-binding periplasmic protein YceI	192
641663207	190	33.69	5	183	4	190	2.0e-25	109	COG2353	Polyisoprenoid-binding periplasmic protein YceI	192
641663208	189	44.25	12	184	7	176	3.0e-34	138	COG3038	Cytochrome b561	181
641663209	319	28.33	16	133	1	111	1.0e-07	50.5	COG0789	DNA-binding transcriptional regulator, MerR family	124
641663210	191	44.51	31	189	1	161	4.0e-51	194	COG0386	Glutathione peroxidase, house-cleaning role in reducing lipid peroxides	162
641663211	439	45.64	1	439	8	434	5.0e-112	398	COG2907	Predicted NAD/FAD-binding protein	447
641663212	276	38.06	29	269	11	249	3.0e-43	168	COG3496	Uncharacterized conserved protein, DUF1365 family	261
641663213	421	49.13	134	420	3	283	1.0e-85	310	COG2230	Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases	283
641663215	428	22.25	1	414	2	435	1.0e-31	131	COG2211	Na+/melibiose symporter or related transporter	467
641663217	257	39.38	11	201	5	197	3.0e-40	158	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
641663219	320	29.32	1	319	4	322	2.0e-57	216	COG0598	Mg2+ and Co2+ transporter CorA	322
641663220	115	44.66	1	103	1	100	1.0e-21	95.3	COG1544	Ribosome-associated translation inhibitor RaiA	110
641663221	156	32	3	150	1	150	5.0e-27	113	COG1762	Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type)	152
641663222	325	38	19	318	12	302	9.0e-74	270	COG1493	Serine kinase of the HPr protein, regulates carbohydrate metabolism	308
641663223	143	43.51	6	136	11	140	5.0e-31	126	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
641663224	182	30.66	5	136	4	133	2.0e-22	98.9	COG2913	Outer membrane protein assembly factor BamE, lipoprotein component of the BamABCDE complex	147
641663225	269	53.56	3	268	1	266	4.0e-89	321	COG0289	Dihydrodipicolinate reductase	266
641663226	233	35.68	8	216	2	214	7.0e-35	140	COG0811	Biopolymer transport protein ExbB/TolQ	216
641663227	146	36.88	1	141	1	137	2.0e-30	124	COG0848	Biopolymer transport protein ExbD	137
641663228	887	46.08	1	887	1	814	0.0e+00	960	COG0495	Leucyl-tRNA synthetase	814
641663229	190	31.18	23	188	8	172	2.0e-18	86.1	COG2980	Outer membrane lipoprotein LptE/RlpB (LPS assembly)	178
641663230	362	28.82	3	340	1	329	1.0e-49	190	COG1466	DNA polymerase III, delta subunit	334
641663231	96	61.46	1	96	1	96	3.0e-33	133	COG0234	Co-chaperonin GroES (HSP10)	96
641663232	549	47.64	1	534	1	524	0.0e+00	481	COG0459	Chaperonin GroEL (HSP60 family)	524
641663234	136	32.8	2	121	1	125	3.0e-12	64.2	COG4969	Tfp pilus assembly protein, major pilin PilA	125
641663236	566	23.96	63	252	35	226	1.0e-12	68.8	COG3063	Tfp pilus assembly protein PilF	250
641663238	605	20.28	16	432	19	422	8.0e-11	62.5	COG3307	O-antigen ligase	424
641663239	504	23.54	12	502	5	459	2.0e-35	144	COG2865	Predicted transcriptional regulator, contains HTH domain	467
641663240	144	65.97	1	144	15	157	1.0e-50	191	COG0315	Molybdenum cofactor biosynthesis enzyme	157
641663241	553	32.05	20	539	11	484	8.0e-58	218	COG4783	Putative Zn-dependent protease, contains TPR repeats	484
641663242	122	44.92	5	121	1	118	2.0e-12	64.8	COG1950	Uncharacterized membrane protein YvlD, DUF360 family	120
641663243	297	56.04	1	297	1	289	3.0e-101	361	COG0074	Succinyl-CoA synthetase, alpha subunit	293
641663244	386	56.7	1	386	1	385	0.0e+00	517	COG0045	Succinyl-CoA synthetase, beta subunit	387
641663245	157	36.18	10	157	22	173	7.0e-21	93.4	COG2137	SOS response regulatory protein OraA/RecX, interacts with RecA	174
641663246	353	66.67	12	287	6	276	3.0e-87	315	COG0468	RecA/RadA recombinase	279
641663247	223	44.49	1	219	1	226	2.0e-53	202	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
641663248	518	31.71	154	501	20	335	8.0e-41	161	COG0642	Signal transduction histidine kinase	336
641663249	384	40.58	10	379	3	372	8.0e-74	270	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
641663250	679	34.95	2	621	1	596	6.0e-130	458	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
641663251	168	39.24	4	158	2	159	1.0e-20	92.6	COG2891	Cell shape-determining protein MreD	167
641663252	312	29.58	12	294	1	284	3.0e-45	175	COG1792	Cell shape-determining protein MreC	284
641663253	349	66.38	7	349	1	342	0.0e+00	461	COG1077	Actin-like ATPase involved in cell morphogenesis	342
641663254	99	44.44	1	99	1	95	8.0e-18	81.8	COG0721	Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit	96
641663255	497	51.59	1	494	1	474	0.0e+00	472	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
641663257	432	19.63	6	430	7	416	1.0e-42	167	COG0443	Molecular chaperone DnaK (HSP70)	579
641663260	409	21.25	41	393	39	381	6.0e-20	92.2	COG2814	Predicted arabinose efflux permease, MFS family	394
641663261	370	46.69	131	370	9	250	3.0e-72	266	COG3338	Carbonic anhydrase	250
641663262	146	36.3	6	146	2	146	5.0e-33	133	COG2001	MraZ, DNA-binding transcriptional regulator and inhibitor of RsmH methyltransferase activity	146
641663263	325	50.97	10	314	6	313	6.0e-102	364	COG0275	16S rRNA C1402 N4-methylase RsmH	314
641663264	102	40.26	3	79	22	98	1.0e-11	61.5	COG3116	Cell division protein FtsL, interacts with FtsB, FtsL and FtsQ	105
641663265	614	36.22	53	593	15	597	1.0e-124	441	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
641663266	513	38.83	16	510	3	475	1.0e-106	380	COG0769	UDP-N-acetylmuramyl tripeptide synthase	475
641663267	489	40.87	21	477	14	450	3.0e-101	362	COG0770	UDP-N-acetylmuramyl pentapeptide synthase	451
641663268	393	39.36	24	393	1	316	3.0e-55	209	COG0472	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase	319
641663270	422	37.53	46	422	11	381	4.0e-74	272	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
641663271	370	42.7	5	363	3	354	6.0e-79	287	COG0707	UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase	357
641663272	469	49.36	1	467	3	459	0.0e+00	528	COG0773	UDP-N-acetylmuramate-alanine ligase	459
641663273	329	46.18	10	314	3	316	7.0e-84	304	COG1181	D-alanine-D-alanine ligase and related ATP-grasp enzymes	317
641663274	267	28.75	16	252	26	256	7.0e-28	117	COG1589	Cell division septal protein FtsQ	269
641663275	408	49.03	8	408	7	418	9.0e-120	423	COG0849	Cell division ATPase FtsA	418
641663276	405	52.32	7	326	6	326	8.0e-91	327	COG0206	Cell division GTPase FtsZ	338
641663277	311	56.49	1	308	1	299	4.0e-117	414	COG0774	UDP-3-O-acyl-N-acetylglucosamine deacetylase	300
641663280	183	55.48	5	159	1	153	2.0e-46	178	COG0817	Holliday junction resolvasome RuvABC endonuclease subunit	160
641663281	535	60.89	1	535	2	515	0.0e+00	729	COG0138	AICAR transformylase/IMP cyclohydrolase PurH	515
641663282	78	52	2	76	23	97	3.0e-20	90.4	COG2901	DNA-binding protein Fis (factor for inversion stimulation)	98
641663283	346	44.65	1	325	2	323	9.0e-89	320	COG0042	tRNA-dihydrouridine synthase	323
641663284	160	31.48	1	158	1	161	5.0e-20	90.7	COG1238	Uncharacterized membrane protein YqaA, SNARE-associated domain	161
641663285	504	44.65	14	504	6	497	0.0e+00	583	COG2317	Zn-dependent carboxypeptidase, M32 family	497
641663288	303	51.48	34	301	1	264	9.0e-82	297	COG0548	Acetylglutamate kinase	265
641663289	189	25	1	189	2	199	3.0e-19	88.4	COG4636	Endonuclease, Uma2 family (restriction endonuclease fold)	200
641663290	233	27.16	7	225	6	225	6.0e-22	97.7	COG1011	FMN phosphatase YigB, HAD superfamily	229
641663291	214	22.68	22	214	5	198	2.0e-06	46.2	COG1309	DNA-binding transcriptional regulator, AcrR family	201
641663292	310	57.04	1	289	1	280	2.0e-96	346	COG2607	Predicted ATPase, AAA+ superfamily	287
641663294	68	48.15	14	67	6	59	6.0e-09	52.4	COG3024	Endogenous inhibitor of DNA gyrase, YacG/DUF329 family	65
641663295	251	35.6	1	250	1	244	3.0e-52	198	COG4582	Cell division protein ZapD, interacts with FtsZ	244
641663296	204	42.42	4	201	1	195	1.0e-46	179	COG0237	Dephospho-CoA kinase	201
641663297	315	45.05	91	311	29	248	2.0e-27	116	COG1989	Prepilin signal peptidase PulO (type II secretory pathway) or related peptidase	254
641663298	408	44.05	16	408	3	396	4.0e-110	391	COG1459	Type II secretory pathway, component PulF	397
641663299	574	47.92	74	574	5	500	0.0e+00	550	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
641663300	634	56.69	1	632	2	618	0.0e+00	757	COG0326	Molecular chaperone, HSP90 family	623
641663301	360	31.12	21	359	2	329	1.0e-43	170	COG2334	Ser/Thr protein kinase RdoA involved in Cpx stress response, MazF antagonist	331
641663304	183	41.4	2	183	1	167	8.0e-37	146	COG0629	Single-stranded DNA-binding protein	167
641663305	659	46.07	11	657	4	585	0.0e+00	662	COG0514	Superfamily II DNA helicase RecQ	590
641663306	405	24.38	44	404	2	306	2.0e-26	113	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
641663307	281	18.89	67	279	53	262	2.0e-08	53.5	COG3137	Putative salt-induced outer membrane protein YdiY	262
641663309	413	41.46	10	402	3	393	5.0e-106	377	COG0282	Acetate kinase	396
641663310	339	44.97	9	339	12	345	9.0e-76	277	COG1744	Basic membrane lipoprotein Med, periplasmic binding protein (PBP1-ABC) superfamily	345
641663311	546	50.78	2	514	1	501	0.0e+00	591	COG3845	ABC-type uncharacterized transport system, ATPase component	501
641663312	367	40.56	5	358	7	350	3.0e-64	239	COG4603	ABC-type uncharacterized transport system, permease component	356
641663313	324	44.41	3	324	2	304	9.0e-71	260	COG1079	ABC-type uncharacterized transport system, permease component	304
641663314	506	36.08	25	495	13	471	1.0e-100	360	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
641663315	385	26.88	7	358	2	368	2.0e-58	220	COG1748	Saccharopine dehydrogenase, NADP-dependent	389
641663322	203	16.88	13	162	17	161	2.0e-07	48.8	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
641663323	581	42.51	1	577	1	500	0.0e+00	561	COG0442	Prolyl-tRNA synthetase	500
641663325	192	58.73	6	192	1	189	7.0e-68	250	COG0163	3-polyprenyl-4-hydroxybenzoate decarboxylase	191
641663326	103	65.05	1	103	1	103	6.0e-44	168	COG0278	Glutaredoxin-related protein	105
641663328	280	44.8	7	275	2	276	8.0e-63	234	COG2890	Methylase of polypeptide chain release factors	280
641663329	360	57.58	1	359	1	363	0.0e+00	470	COG0216	Protein chain release factor A	363
641663330	435	44.39	1	419	1	409	2.0e-114	406	COG0373	Glutamyl-tRNA reductase	414
641663332	307	28.17	16	226	20	231	2.0e-20	93	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
641663333	469	49.44	25	466	1	436	0.0e+00	542	COG0621	tRNA A37 methylthiotransferase MiaB	437
641663335	214	53.92	10	212	7	202	7.0e-67	246	COG0378	Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase	202
641663336	69	45.28	1	53	1	52	1.0e-05	41.4	COG2906	Bacterioferritin-associated ferredoxin	63
641663337	158	64.97	1	157	1	157	7.0e-53	199	COG2193	Bacterioferritin (cytochrome b1)	157
641663338	340	32.66	49	333	15	309	2.0e-53	203	COG0616	Periplasmic serine protease, ClpP class	317
641663339	126	31.82	5	114	3	103	8.0e-13	66.1	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
641663340	219	35.48	6	218	4	220	8.0e-43	166	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
641663341	322	41.39	14	312	4	288	4.0e-71	261	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
641663342	1058	52.44	1	490	1	487	0.0e+00	494	COG1530	Ribonuclease G or E	487
641663344	132	39.53	1	128	1	124	2.0e-32	131	COG0736	Phosphopantetheinyl transferase (holo-ACP synthase)	127
641663345	268	37.1	18	262	3	241	1.0e-58	219	COG0854	Pyridoxine 5'-phosphate synthase PdxJ	243
641663346	256	28.46	13	256	10	248	1.0e-27	116	COG1381	Recombinational DNA repair protein (RecF pathway)	251
641663347	348	50	52	348	2	296	7.0e-105	374	COG1159	GTPase Era, involved in 16S rRNA processing	298
641663348	228	45.54	5	223	7	229	5.0e-60	224	COG0571	dsRNA-specific ribonuclease	235
641663350	322	29.56	98	207	8	166	2.0e-13	70	COG0681	Signal peptidase I	166
641663351	602	68.16	1	602	6	602	0.0e+00	1031	COG0481	Translation elongation factor EF-4, membrane-bound GTPase	603
641663352	516	43.27	35	408	2	347	1.0e-69	257	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
641663353	387	22.46	53	386	17	318	1.0e-36	147	COG3026	Negative regulator of sigma E activity	320
641663354	215	23.03	7	184	2	164	3.0e-07	48.9	COG3073	Negative regulator of sigma E activity	213
641663355	202	36.98	6	197	2	182	2.0e-26	112	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641663357	414	55.05	3	414	2	411	0.0e+00	486	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
641663358	79	65.38	1	78	3	80	1.0e-11	61.5	COG0236	Acyl carrier protein	80
641663359	250	48.79	11	247	6	250	6.0e-46	177	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
641663360	312	51.63	1	304	1	304	3.0e-86	311	COG0331	Malonyl CoA-acyl carrier protein transacylase	310
641663361	330	55.96	7	330	2	322	2.0e-110	392	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
641663362	363	50.89	5	336	2	332	4.0e-115	408	COG0416	Fatty acid/phospholipid biosynthesis enzyme	338
641663363	60	42.11	1	56	1	57	3.0e-11	59.9	COG0333	Ribosomal protein L32	57
641663365	205	39.9	6	197	3	193	3.0e-47	181	COG0424	Predicted house-cleaning NTP pyrophosphatase, Maf/HAM1 superfamily	193
641663366	265	30.64	13	246	5	205	2.0e-32	132	COG0313	16S rRNA C1402 (ribose-2'-O) methylase RsmI	275
641663367	479	40.77	14	470	28	487	4.0e-115	408	COG0513	Superfamily II DNA and RNA helicase	513
641663368	373	24.67	1	300	2	298	7.0e-32	131	COG0472	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase	319
641663369	355	65.43	2	350	3	340	0.0e+00	555	COG1088	dTDP-D-glucose 4,6-dehydratase	340
641663370	296	50	1	292	1	279	3.0e-87	315	COG1091	dTDP-4-dehydrorhamnose reductase	281
641663371	293	57.79	3	291	1	286	2.0e-118	418	COG1209	dTDP-glucose pyrophosphorylase	286
641663372	183	57.87	1	178	1	173	3.0e-59	221	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase or related enzyme	173
641663373	481	46.49	7	344	2	333	1.0e-114	406	COG0836	Mannose-1-phosphate guanylyltransferase	333
641663373	481	49.61	353	479	1	127	1.0e-37	151	COG0662	Mannose-6-phosphate isomerase, cupin superfamily	127
641663374	308	33.23	6	302	2	306	8.0e-45	174	COG0451	Nucleoside-diphosphate-sugar epimerase	314
641663377	374	70.9	6	359	3	345	0.0e+00	575	COG1089	GDP-D-mannose dehydratase	345
641663378	196	25.14	19	189	23	199	5.0e-21	94.6	COG4636	Endonuclease, Uma2 family (restriction endonuclease fold)	200
641663379	408	20.79	1	403	1	380	9.0e-26	111	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
641663384	238	36.29	4	226	10	246	1.0e-38	153	COG1922	UDP-N-acetyl-D-mannosaminuronic acid transferase, WecB/TagA/CpsF family	253
641663385	403	25.62	92	402	71	379	1.0e-24	108	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
641663387	468	20.55	4	432	10	438	1.0e-14	74.8	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
641663388	376	42.06	1	376	5	372	3.0e-103	368	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
641663389	188	25.68	23	170	41	178	2.0e-10	59.1	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
641663391	427	51.52	7	426	11	423	0.0e+00	525	COG0677	UDP-N-acetyl-D-mannosaminuronate dehydrogenase	436
641663392	360	54.21	1	352	19	367	4.0e-127	447	COG0381	UDP-N-acetylglucosamine 2-epimerase	383
641663393	398	21.6	62	377	41	368	4.0e-13	69.6	COG3524	Capsule polysaccharide export protein KpsE/RkpR	372
641663398	779	28.23	129	332	32	239	3.0e-18	87.5	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
641663400	340	23.26	9	180	6	172	1.0e-20	94.3	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
641663401	629	30.13	402	627	21	257	2.0e-31	131	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
641663402	306	24.31	32	303	25	283	2.0e-09	56.9	COG1767	Triphosphoribosyl-dephospho-CoA synthetase	288
641663403	129	38.89	14	121	19	122	1.0e-18	85.7	COG1664	Cytoskeletal protein CcmA, bactofilin family	146
641663406	178	37.13	7	173	12	176	3.0e-35	141	COG2229	Signal recognition particle receptor subunit beta, a GTPase	187
641663408	120	39.32	4	120	3	119	5.0e-22	96.4	COG2018	Predicted regulator of Ras-like GTPase activity, Roadblock/LC7/MglB family	119
641663413	407	37.32	4	394	3	406	1.0e-87	317	COG0004	Ammonia channel protein AmtB	409
641663414	301	48.51	4	296	2	300	2.0e-97	349	COG0031	Cysteine synthase	300
641663416	200	32.38	2	200	14	221	3.0e-21	95.2	COG0705	Membrane associated serine protease, rhomboid family	228
641663417	384	24.18	31	377	1	344	5.0e-22	99.2	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
641663418	322	25.25	37	307	2	289	9.0e-18	84.6	COG0451	Nucleoside-diphosphate-sugar epimerase	314
641663419	343	30.12	9	88	12	94	2.0e-09	57	COG0633	Ferredoxin	102
641663419	343	39.21	101	327	6	219	7.0e-49	187	COG0543	NAD(P)H-flavin reductase	252
641663420	100	49.41	13	97	3	87	4.0e-08	49.5	COG0268	Ribosomal protein S20	88
641663421	520	48.28	1	519	7	517	2.0e-110	393	COG0728	Peptidoglycan biosynthesis protein MviN/MurJ, putative lipid II flippase	518
641663422	290	34.46	17	283	8	263	1.0e-37	150	COG2912	Regulator of sirC expression, contains transglutaminase-like and TPR domains	269
641663423	353	34.6	11	351	17	350	1.0e-29	124	COG0628	Predicted PurR-regulated permease PerM	355
641663425	227	31.34	8	224	7	204	8.0e-31	127	COG0560	Phosphoserine phosphatase	212
641663426	498	32.8	33	464	1	408	2.0e-72	267	COG0617	tRNA nucleotidyltransferase/poly(A) polymerase	412
641663427	162	51.53	1	162	1	159	4.0e-41	160	COG0801	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase	160
641663428	215	33.33	1	214	3	217	7.0e-34	137	COG1392	Uncharacterized conserved protein YkaA, distantly related to PhoU, UPF0111/DUF47 family	217
641663429	336	39.7	7	336	1	326	2.0e-62	232	COG0306	Phosphate/sulfate permease	326
641663431	186	44.71	3	171	1	169	1.0e-41	162	COG1247	L-amino acid N-acyltransferase YncA	169
641663432	86	56.41	1	78	1	77	1.0e-23	101	COG0228	Ribosomal protein S16	87
641663433	194	33.51	10	194	4	172	4.0e-36	144	COG0806	Ribosomal 30S subunit maturation factor RimM, required for 16S rRNA processing	174
641663434	249	50.6	1	248	1	240	2.0e-90	325	COG0336	tRNA G37 N-methylase TrmD	240
641663435	117	65.52	1	116	3	115	5.0e-38	149	COG0335	Ribosomal protein L19	115
641663437	329	27.6	3	329	10	319	7.0e-33	134	COG1270	Cobalamin biosynthesis protein CobD/CbiB	320
641663438	241	35.65	11	240	2	231	3.0e-47	182	COG3821	Uncharacterized membrane protein	234
641663439	236	40	1	236	1	244	6.0e-47	180	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
641663440	332	26.1	8	322	1	295	1.0e-23	103	COG0583	DNA-binding transcriptional regulator, LysR family	297
641663444	431	56.15	1	426	1	422	0.0e+00	563	COG0172	Seryl-tRNA synthetase	429
641663445	327	64.97	9	301	1	294	2.0e-119	422	COG0761	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH	294
641663446	150	34	3	150	2	141	7.0e-24	103	COG1047	FKBP-type peptidyl-prolyl cis-trans isomerase 2	174
641663447	222	53.6	1	222	3	224	2.0e-69	255	COG2003	DNA repair protein RadC, contains a helix-hairpin-helix DNA-binding motif	224
641663448	226	42.11	41	211	9	178	2.0e-29	122	COG2840	DNA-nicking endonuclease, Smr domain	184
641663449	142	33.59	14	141	1	125	5.0e-27	113	COG2346	Truncated hemoglobin YjbI	133
641663450	273	40.08	20	267	1	238	6.0e-45	174	COG0455	MinD-like ATPase involved in chromosome partitioning or flagellar assembly	262
641663451	226	45.98	21	194	9	180	4.0e-43	167	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
641663452	284	44	21	284	1	266	6.0e-72	264	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
641663453	219	43.95	35	187	1	157	9.0e-48	183	COG1871	Chemotaxis receptor (MCP) glutamine deamidase CheD	164
641663454	384	50.53	3	379	1	349	2.0e-101	362	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
641663455	457	40.23	26	457	6	411	1.0e-105	377	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
641663456	212	45.67	1	207	2	192	5.0e-53	200	COG0127	Inosine/xanthosine triphosphate pyrophosphatase, all-alpha NTP-PPase family	194
641663457	241	57.38	5	240	9	230	1.0e-74	273	COG0689	Ribonuclease PH	230
641663458	304	34.66	1	243	6	253	2.0e-43	169	COG0631	Serine/threonine protein phosphatase PrpC	262
641663459	292	23.55	2	288	16	303	2.0e-21	96.8	COG0515	Serine/threonine protein kinase	384
641663460	302	37.79	3	302	2	290	1.0e-56	213	COG1561	Uncharacterized conserved protein YicC, UPF0701 family	290
641663461	438	20.98	112	394	39	259	9.0e-22	98.5	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
641663463	277	42.75	6	267	5	254	5.0e-57	214	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
641663464	324	36.45	1	321	1	317	3.0e-54	205	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
641663465	358	20.26	1	358	1	354	3.0e-20	92.7	COG3203	Outer membrane protein (porin)	354
641663466	307	31.34	44	302	26	292	7.0e-29	121	COG3386	Sugar lactone lactonase YvrE	307
641663467	323	35.13	1	315	1	312	3.0e-56	212	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
641663469	307	40.82	18	307	18	308	3.0e-67	248	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
641663470	232	41.67	9	212	1	200	4.0e-40	158	COG0684	Regulator of RNase E activity RraA	210
641663471	326	41.19	6	322	1	316	7.0e-72	264	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
641663472	298	32.99	1	292	1	290	2.0e-32	133	COG0583	DNA-binding transcriptional regulator, LysR family	297
641663473	170	24.83	23	165	19	163	4.0e-08	51.3	COG4925	Uncharacterized protein	166
641663474	368	28.05	41	361	1	299	1.0e-29	124	COG1073	Fermentation-respiration switch protein FrsA, has esterase activity, DUF1100 family	299
641663475	331	40.48	182	307	1	126	3.0e-20	92.6	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
641663476	482	37.32	8	480	1	458	9.0e-103	367	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
641663478	475	30.55	26	443	1	383	7.0e-62	231	COG0348	Polyferredoxin	386
641663479	209	54.59	8	192	4	187	7.0e-65	240	COG0194	Guanylate kinase	191
641663480	67	48.57	1	67	1	70	2.0e-11	60.7	COG1758	DNA-directed RNA polymerase, subunit K/omega	74
641663481	769	40.78	53	767	19	701	0.0e+00	789	COG0317	(p)ppGpp synthase/hydrolase, HD superfamily	701
641663482	189	42.48	33	184	1	151	5.0e-33	134	COG0782	Transcription elongation factor, GreA/GreB family	151
641663485	235	45.85	4	229	2	228	3.0e-55	208	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
641663486	431	33.33	131	425	25	328	2.0e-34	140	COG0642	Signal transduction histidine kinase	336
641663490	209	53.3	2	198	1	197	1.0e-73	268	COG0299	Folate-dependent phosphoribosylglycinamide formyltransferase PurN	200
641663491	418	40.78	112	418	48	354	2.0e-75	276	COG0144	16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family	355
641663492	407	36.02	10	269	29	289	2.0e-73	270	COG1398	Fatty-acid desaturase	289
641663495	919	57.74	2	912	1	822	0.0e+00	1063	COG0653	Preprotein translocase subunit SecA (ATPase, RNA helicase)	822
641663496	409	51.83	2	409	1	404	0.0e+00	493	COG1364	N-acetylglutamate synthase (N-acetylornithine aminotransferase)	404
641663498	356	35.4	12	338	7	338	5.0e-63	235	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
641663499	257	38.8	10	251	5	250	1.0e-38	153	COG0584	Glycerophosphoryl diester phosphodiesterase	257
641663500	1309	24.04	895	1289	1	388	2.0e-46	182	COG0247	Fe-S oxidoreductase	388
641663502	56	54	5	54	1	50	3.0e-10	56.8	COG0267	Ribosomal protein L33	50
641663503	77	64.94	1	76	1	77	2.0e-22	97.7	COG0227	Ribosomal protein L28	77
641663504	321	50.64	6	317	2	303	1.0e-92	333	COG0492	Thioredoxin reductase	305
641663505	222	33.64	9	218	1	214	1.0e-30	126	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
641663507	212	32.55	5	212	1	210	1.0e-34	139	COG2834	Outer membrane lipoprotein-sorting protein	211
641663508	447	54.59	16	445	3	436	0.0e+00	562	COG2256	Replication-associated recombination protein RarA (DNA-dependent ATPase)	436
641663509	311	41.29	1	310	3	297	6.0e-54	204	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
641663510	361	38.44	6	351	6	309	1.0e-48	186	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
641663511	258	55.34	2	253	1	250	2.0e-89	322	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
641663512	241	52.97	7	240	1	236	3.0e-83	301	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
641663513	950	48.27	34	950	4	910	0.0e+00	1020	COG2352	Phosphoenolpyruvate carboxylase	910
641663514	322	52.26	11	318	1	305	1.0e-95	342	COG0181	Porphobilinogen deaminase	307
641663515	267	29.57	10	263	2	241	3.0e-21	95.9	COG1587	Uroporphyrinogen-III synthase	248
641663516	354	24.78	1	338	35	342	2.0e-23	103	COG2959	Uncharacterized conserved protein HemX (no evidence of involvement in heme biosynthesis)	391
641663517	415	23.13	1	411	1	387	7.0e-31	128	COG3071	Uncharacterized conserved protein HemY, contains two TPR repeats	400
641663519	337	34.13	14	299	7	281	8.0e-37	148	COG4974	Site-specific recombinase XerD	300
641663520	326	24.18	33	299	34	281	2.0e-16	80.6	COG4974	Site-specific recombinase XerD	300
641663521	417	23.57	118	408	2	292	7.0e-22	98.7	COG4974	Site-specific recombinase XerD	300
641663526	339	31.76	12	301	3	281	2.0e-42	166	COG4974	Site-specific recombinase XerD	300
641663528	425	24.7	177	416	52	292	3.0e-20	93.3	COG4974	Site-specific recombinase XerD	300
641663529	99	28.71	1	99	1	99	6.0e-06	42.5	COG2963	Transposase and inactivated derivatives	116
641663530	295	36.91	56	288	19	232	4.0e-23	101	COG2801	Transposase InsO and inactivated derivatives	232
641663531	161	28.91	26	147	23	150	2.0e-08	52	COG0629	Single-stranded DNA-binding protein	167
641663533	281	25.28	1	262	2	259	5.0e-28	118	COG1192	Cellulose biosynthesis protein BcsQ	259
641663538	210	40.49	1	199	2	204	8.0e-29	120	COG2085	Predicted dinucleotide-binding enzyme	211
641663539	206	25.89	6	200	9	198	1.0e-24	106	COG0400	Predicted esterase	207
641663540	239	48.74	3	239	1	237	2.0e-75	275	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
641663541	248	45.38	1	245	2	250	1.0e-72	266	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
641663542	335	37.34	11	311	4	310	7.0e-35	141	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
641663543	306	36.48	1	301	1	290	4.0e-36	145	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
641663544	386	32.35	15	345	1	340	2.0e-40	160	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
641663545	105	40.38	4	105	3	106	2.0e-23	101	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
641663546	160	26.11	12	160	9	163	2.0e-30	125	COG5517	3-phenylpropionate/cinnamic acid dioxygenase, small subunit	164
641663547	419	24.5	21	416	4	367	6.0e-51	195	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
641663548	231	44.29	22	229	57	262	4.0e-61	227	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
641663549	348	53.12	14	348	13	348	3.0e-115	408	COG3435	Gentisate 1,2-dioxygenase	351
641663550	328	29.07	10	90	15	100	9.0e-12	64.7	COG0633	Ferredoxin	102
641663550	328	36.32	96	316	5	219	3.0e-45	175	COG0543	NAD(P)H-flavin reductase	252
641663551	309	24.33	6	304	1	297	2.0e-29	122	COG0583	DNA-binding transcriptional regulator, LysR family	297
641663553	581	35.61	66	577	1	533	3.0e-94	339	COG2303	Choline dehydrogenase or related flavoprotein	542
641663554	483	43.84	3	479	1	472	3.0e-120	425	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
641663555	351	32.36	10	349	1	333	2.0e-57	216	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
641663556	419	16.36	59	414	51	422	1.0e-08	55.2	COG2211	Na+/melibiose symporter or related transporter	467
641663557	554	28.24	27	406	1	360	2.0e-46	180	COG1472	Periplasmic beta-glucosidase and related glycosidases	397
641663558	733	19.89	12	733	29	768	5.0e-27	116	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
641663559	283	24.56	7	278	2	279	1.0e-25	110	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
641663560	275	21.03	53	253	8	205	1.0e-08	53.9	COG0412	Dienelactone hydrolase	236
641663562	142	29.93	3	139	1	135	2.0e-20	91.4	COG0848	Biopolymer transport protein ExbD	137
641663563	136	41.18	1	136	1	135	2.0e-25	107	COG0848	Biopolymer transport protein ExbD	137
641663564	265	33.33	57	263	1	213	7.0e-32	131	COG0811	Biopolymer transport protein ExbB/TolQ	216
641663566	289	27.42	22	264	1	246	2.0e-32	133	COG1414	DNA-binding transcriptional regulator, IclR family	246
641663567	251	36.9	4	249	2	250	2.0e-39	156	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
641663568	409	35.86	3	396	5	396	1.0e-71	264	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
641663569	292	28.98	23	266	14	246	1.0e-33	137	COG3777	Hydroxyacyl-ACP dehydratase HTD2, hotdog domain	273
641663570	140	20.14	4	136	2	138	1.0e-05	42.5	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
641663571	352	34.66	23	347	4	326	1.0e-71	264	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
641663572	628	31.91	24	164	4	144	2.0e-17	85	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
641663572	628	33.87	254	628	1	375	6.0e-75	275	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
641663573	307	24.51	1	285	1	294	8.0e-22	98.1	COG0451	Nucleoside-diphosphate-sugar epimerase	314
641663574	256	36.43	1	252	1	249	1.0e-42	166	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
641663575	136	27.59	3	117	10	124	4.0e-07	47.5	COG1917	Cupin domain protein related to quercetin dioxygenase	131
641663576	107	16.84	1	93	2	95	8.0e-08	48.8	COG2329	Heme-degrading monooxygenase HmoA and related ABM domain proteins	105
641663578	301	32.56	5	301	2	297	7.0e-33	134	COG0583	DNA-binding transcriptional regulator, LysR family	297
641663579	67	35.94	1	63	1	64	4.0e-11	59.6	COG1942	Phenylpyruvate tautomerase PptA, 4-oxalocrotonate tautomerase family	69
641663580	137	33.33	1	126	1	122	9.0e-24	102	COG3791	Uncharacterized conserved protein	133
641663581	400	42.72	1	400	1	392	5.0e-83	301	COG0183	Acetyl-CoA acetyltransferase	392
641663582	220	54.38	3	218	1	216	2.0e-71	262	COG2057	Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit	225
641663583	233	55.25	2	220	1	217	8.0e-72	263	COG1788	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit	220
641663584	294	33.99	50	251	1	187	9.0e-37	147	COG3485	Protocatechuate 3,4-dioxygenase beta subunit	226
641663585	307	30.77	3	296	2	294	8.0e-34	137	COG0583	DNA-binding transcriptional regulator, LysR family	297
641663587	356	32.63	7	349	1	377	1.0e-72	267	COG1454	Alcohol dehydrogenase, class IV	377
641663588	367	23.51	15	361	3	335	3.0e-36	146	COG0673	Predicted dehydrogenase	342
641663589	292	23.01	26	256	11	246	2.0e-17	83.3	COG1082	Sugar phosphate isomerase/epimerase	274
641663590	331	38.01	1	331	3	340	8.0e-56	210	COG0673	Predicted dehydrogenase	342
641663591	355	33.63	9	344	9	341	5.0e-45	175	COG4213	ABC-type xylose transport system, periplasmic component	341
641663593	407	36.65	20	395	12	387	3.0e-60	226	COG4214	ABC-type xylose transport system, permease component	394
641663594	400	41.99	1	400	1	392	2.0e-83	303	COG0183	Acetyl-CoA acetyltransferase	392
641663595	687	41.5	289	590	1	306	2.0e-76	280	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
641663595	687	44.5	1	192	5	204	1.0e-35	144	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
641663596	415	49.63	8	415	3	396	9.0e-124	437	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
641663597	386	44.3	10	385	11	389	6.0e-85	308	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
641663599	528	23.64	8	521	115	736	6.0e-44	172	COG4993	Glucose dehydrogenase	773
641663600	119	27.83	1	111	15	125	7.0e-06	43	COG2010	Cytochrome c, mono- and diheme variants	150
641663601	558	26.29	8	529	122	719	1.0e-66	247	COG4993	Glucose dehydrogenase	773
641663602	365	25.28	9	359	3	336	1.0e-38	154	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
641663603	185	28.38	17	163	8	151	4.0e-27	114	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
641663604	659	37.73	4	654	6	606	4.0e-120	425	COG3284	Transcriptional regulator of acetoin/glycerol metabolism	606
641663605	405	59.28	204	397	2	193	3.0e-65	242	COG0807	GTP cyclohydrolase II	193
641663605	405	64.36	1	202	1	201	4.0e-81	295	COG0108	3,4-dihydroxy-2-butanone 4-phosphate synthase	203
641663606	479	43.55	6	476	1	467	0.0e+00	462	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
641663607	249	50.38	1	249	1	260	2.0e-70	258	COG2086	Electron transfer flavoprotein, alpha and beta subunits	260
641663608	309	54.92	1	309	1	310	1.0e-81	297	COG2025	Electron transfer flavoprotein, alpha subunit	313
641663611	230	27.27	77	214	47	187	5.0e-10	58.3	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
641663612	677	30.69	22	590	21	577	2.0e-86	314	COG3505	Type IV secretory pathway, VirD4 component, TraG/TraD family ATPase	596
641663613	368	31.41	30	340	15	295	6.0e-53	201	COG0630	Type IV secretory pathway ATPase VirB11/Archaellum biosynthesis ATPase	312
641663614	492	28.04	167	485	50	359	1.0e-33	138	COG2948	Type IV secretory pathway, VirB10 components	360
641663615	315	26.9	12	297	3	261	1.0e-26	113	COG3504	Type IV secretory pathway, VirB9 components	265
641663616	290	31.82	63	282	22	234	8.0e-29	121	COG3736	Type IV secretory pathway, component VirB8	239
641663618	345	16.87	27	334	71	383	1.0e-09	57.7	COG3704	Type IV secretory pathway, VirB6 components	406
641663620	830	37.59	32	823	13	796	0.0e+00	580	COG3451	Type IV secretory pathway, VirB4 component	796
641663621	110	25.53	6	98	10	95	1.0e-09	54.9	COG3702	Type IV secretory pathway, VirB3 components	105
641663627	141	53.08	1	129	1	130	6.0e-36	143	COG3602	Uncharacterized protein	134
641663628	314	26.03	2	281	6	292	6.0e-17	81.7	COG3239	Fatty acid desaturase	343
641663630	284	26.81	2	273	1	270	3.0e-20	92.8	COG0583	DNA-binding transcriptional regulator, LysR family	297
641663632	75	49.06	19	71	13	65	2.0e-10	57.2	COG3311	Predicted DNA-binding transcriptional regulator AlpA	70
641663633	326	39.06	1	319	14	318	3.0e-70	259	COG2826	Transposase and inactivated derivatives, IS30 family	318
641663634	474	26.6	1	470	1	497	1.0e-43	171	COG1070	Sugar (pentulose or hexulose) kinase	502
641663635	333	32.29	1	332	2	350	3.0e-52	199	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
641663636	260	33.46	3	253	9	257	4.0e-33	134	COG1830	Fructose-bisphosphate aldolase class Ia, DhnA family	265
641663637	253	32.64	12	250	1	236	7.0e-36	144	COG2188	DNA-binding transcriptional regulator, GntR family	236
641663639	435	25.29	5	430	15	432	9.0e-34	138	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
641663640	280	35.84	1	276	10	287	1.0e-47	183	COG1175	ABC-type sugar transport system, permease component	295
641663641	276	34.16	1	276	1	281	5.0e-48	184	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
641663642	357	53.12	1	352	1	338	5.0e-124	437	COG3839	ABC-type sugar transport system, ATPase component	338
641663643	546	38.23	5	323	3	322	3.0e-60	226	COG2376	Dihydroxyacetone kinase	323
641663644	467	34.91	3	461	17	464	4.0e-102	365	COG0246	Mannitol-1-phosphate/altronate dehydrogenases	473
641663645	302	26.83	175	297	3	125	2.0e-17	83	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
641663646	406	22.03	23	375	23	345	7.0e-17	82.1	COG3177	Fic family protein	348
641663650	202	47.42	4	193	3	213	5.0e-46	177	COG1926	Predicted phosphoribosyltransferase	220
641663651	235	42.38	13	221	1	210	5.0e-48	184	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
641663652	509	32.6	220	485	95	365	7.0e-43	168	COG4585	Signal transduction histidine kinase	365
641663653	287	33.33	41	246	6	212	1.0e-30	127	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
641663656	402	46.92	11	397	16	401	0.0e+00	461	COG4992	Acetylornithine/succinyldiaminopimelate/putrescine aminotransferase	404
641663657	320	50.94	5	315	3	309	4.0e-113	401	COG0078	Ornithine carbamoyltransferase	310
641663659	304	25.36	24	293	2	258	2.0e-14	73	COG3713	Outer membrane scaffolding protein for murein synthesis, MipA/OmpV family	258
641663661	479	21.73	19	310	1	310	3.0e-31	130	COG0515	Serine/threonine protein kinase	384
641663661	479	28.29	328	473	8	154	2.0e-08	54.2	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
641663662	446	35.61	9	430	1	403	1.0e-126	446	COG0137	Argininosuccinate synthase	403
641663663	104	44.09	11	103	2	93	3.0e-30	123	COG3123	Uncharacterized conserved protein YaiE, UPF0345 family	94
641663664	166	37.69	38	166	26	155	3.0e-30	124	COG3915	Uncharacterized protein	155
641663665	822	29.82	164	503	21	336	8.0e-42	166	COG0642	Signal transduction histidine kinase	336
641663665	822	42.98	534	645	5	115	6.0e-18	86.8	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
641663667	456	59.04	1	455	1	456	0.0e+00	616	COG1066	Predicted ATP-dependent serine protease	456
641663668	209	39.02	1	204	1	205	4.0e-27	114	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
641663670	377	45.04	1	368	1	355	8.0e-100	357	COG0787	Alanine racemase	360
641663674	398	54.8	1	396	1	396	0.0e+00	553	COG1448	Aspartate/tyrosine/aromatic aminotransferase	396
641663675	323	28.25	6	312	1	297	4.0e-24	105	COG0583	DNA-binding transcriptional regulator, LysR family	297
641663678	494	42.92	17	494	4	470	4.0e-111	395	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
641663679	140	52.86	1	140	1	129	3.0e-36	144	COG1970	Large-conductance mechanosensitive channel	130
641663680	198	31.98	1	195	2	168	2.0e-29	122	COG0723	Rieske Fe-S protein	177
641663681	467	44.91	16	446	6	372	5.0e-89	321	COG1290	Cytochrome b subunit of the bc complex	381
641663682	260	33.46	5	260	2	250	7.0e-47	180	COG2857	Cytochrome c1	250
641663683	204	37.62	2	194	1	201	2.0e-29	122	COG0625	Glutathione S-transferase	211
641663684	185	38.86	12	185	6	155	6.0e-37	147	COG2969	Stringent starvation protein B	155
641663686	221	34.53	6	219	10	232	4.0e-38	151	COG0176	Transaldolase	239
641663687	151	45.38	1	116	1	119	2.0e-26	111	COG2832	Uncharacterized membrane protein YbaN, DUF454 family	119
641663688	436	40.54	8	373	1	345	8.0e-71	261	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
641663690	487	40.6	25	486	1	454	6.0e-117	414	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
641663691	373	65.44	21	372	3	350	0.0e+00	550	COG0722	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase	351
641663693	191	51.11	4	181	3	178	3.0e-51	194	COG2096	Cob(I)alamin adenosyltransferase	184
641663694	254	21.1	18	249	12	215	2.0e-10	59.3	COG3318	Uncharacterized conserved protein YecA, UPF0149 family, contains C-terminal Zn-binding SEC-C motif	216
641663695	140	27.7	1	140	6	151	6.0e-10	56.9	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
641663697	525	34.14	1	522	1	518	1.0e-99	357	COG3540	Phosphodiesterase/alkaline phosphatase D	522
641663698	311	24.91	4	279	1	279	1.0e-18	87.4	COG0583	DNA-binding transcriptional regulator, LysR family	297
641663699	435	28.21	1	429	5	384	2.0e-38	153	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
641663701	207	28.57	1	203	1	201	2.0e-20	92.9	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
641663705	388	22.71	82	318	41	272	1.0e-05	44.8	COG4974	Site-specific recombinase XerD	300
641663706	360	26.84	79	349	1	226	7.0e-15	75.2	COG3039	Transposase and inactivated derivatives, IS5 family	230
641663707	222	37.67	7	218	5	216	3.0e-37	148	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
641663708	235	56.6	1	232	9	241	1.0e-87	316	COG2227	2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase	243
641663709	243	39.41	69	238	22	190	2.0e-32	132	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
641663710	885	55.1	1	859	1	804	0.0e+00	1043	COG0188	DNA gyrase/topoisomerase IV, subunit A	804
641663712	374	42.17	18	98	10	92	1.0e-18	88.1	COG1605	Chorismate mutase	101
641663712	374	46.35	100	370	2	273	6.0e-88	317	COG0077	Prephenate dehydratase	279
641663713	293	37.54	1	283	2	279	1.0e-61	230	COG0287	Prephenate dehydrogenase	279
641663714	699	40	17	470	15	426	2.0e-114	406	COG0128	5-enolpyruvylshikimate-3-phosphate synthase	428
641663714	699	49.55	474	691	2	221	8.0e-65	242	COG0283	Cytidylate kinase	222
641663715	562	53.28	1	547	2	540	0.0e+00	582	COG0539	Ribosomal protein S1	541
641663716	112	50	1	92	2	92	8.0e-28	115	COG0776	Bacterial nucleoid DNA-binding protein	94
641663717	106	26.03	6	78	27	98	9.0e-06	42.2	COG5416	Uncharacterized integral membrane protein	98
641663718	384	33.85	4	383	1	387	3.0e-72	266	COG2956	Lipopolysaccharide biosynthesis regulator YciM, contains six TPR domains and a predicted metal-binding C-terminal domain	389
641663719	309	36.13	1	265	12	277	4.0e-49	188	COG0859	ADP-heptose:LPS heptosyltransferase	334
641663722	330	20.1	89	257	37	223	1.0e-06	48	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
641663726	356	21.64	2	356	19	380	7.0e-19	88.5	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
641663727	315	24.09	6	294	5	296	1.0e-26	113	COG0859	ADP-heptose:LPS heptosyltransferase	334
641663729	422	24.86	12	359	2	289	3.0e-19	90.1	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
641663730	1188	45.32	1	1157	2	1119	0.0e+00	1189	COG0587	DNA polymerase III, alpha subunit	1139
641663731	247	42.51	1	244	1	240	2.0e-73	269	COG1054	Predicted sulfurtransferase	308
641663732	300	26.78	3	295	1	289	1.0e-21	97.4	COG0583	DNA-binding transcriptional regulator, LysR family	297
641663733	320	37.46	4	316	1	292	1.0e-68	253	COG1162	Putative ribosome biogenesis GTPase RsgA	301
641663734	427	24.36	122	424	11	293	4.0e-19	89.6	COG0501	Zn-dependent protease with chaperone function	302
641663735	187	67.23	10	186	4	180	3.0e-76	277	COG1949	Oligoribonuclease (3'-5' exoribonuclease)	184
641663736	155	34.92	27	151	1	126	3.0e-10	58	COG1846	DNA-binding transcriptional regulator, MarR family	126
641663737	597	31.72	37	464	7	386	2.0e-51	197	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
641663738	247	53.81	7	240	3	236	2.0e-82	298	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
641663739	593	37.46	1	312	1	310	3.0e-54	206	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
641663739	593	50.79	343	591	2	250	6.0e-81	295	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
641663740	345	30.77	1	335	1	285	2.0e-30	126	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
641663741	380	28.93	15	359	1	341	4.0e-41	162	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
641663742	254	37.5	1	250	1	251	8.0e-28	117	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
641663743	626	28.46	33	518	4	463	1.0e-60	228	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
641663744	273	34	22	267	7	255	2.0e-41	162	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
641663745	287	32.19	1	287	11	291	4.0e-53	201	COG2159	Predicted metal-dependent hydrolase, TIM-barrel fold	293
641663747	257	34.33	1	254	2	266	4.0e-48	185	COG1018	Ferredoxin-NADP reductase	266
641663748	210	36.82	19	210	18	217	4.0e-34	138	COG3143	Chemotaxis regulator CheZ, phosphatase of CheY~P	217
641663750	320	32.96	12	278	1	243	4.0e-45	175	COG1360	Flagellar motor protein MotB	244
641663751	285	40.49	1	284	3	263	1.0e-66	246	COG1291	Flagellar motor component MotA	266
641663760	287	32.12	5	275	3	276	4.0e-26	112	COG1344	Flagellin and related hook-associated protein FlgL	360
641663761	479	34.83	1	477	3	483	5.0e-54	205	COG1345	Flagellar capping protein FliD	483
641663762	139	40	24	133	12	120	1.0e-21	95.4	COG1516	Flagellin-specific chaperone FliS	132
641663764	251	21.83	27	249	9	230	5.0e-11	61.8	COG5581	c-di-GMP-binding flagellar brake protein YcgR, contains PilZNR and PilZ domains	233
641663765	122	35.71	39	122	23	105	2.0e-10	58	COG1677	Flagellar hook-basal body complex protein FliE	105
641663766	576	38.64	26	572	15	543	2.0e-110	393	COG1766	Flagellar biosynthesis/type III secretory pathway M-ring protein FliF/YscJ	545
641663767	333	46.22	1	330	7	337	2.0e-78	285	COG1536	Flagellar motor switch protein FliG	339
641663768	261	25.96	20	251	3	232	3.0e-23	102	COG1317	Flagellar biosynthesis/type III secretory pathway protein FliH	234
641663769	466	54.35	7	465	4	441	0.0e+00	572	COG1157	Flagellar biosynthesis/type III secretory pathway ATPase	441
641663770	159	30.07	8	150	6	148	4.0e-08	51.1	COG2882	Flagellar biosynthesis chaperone FliJ	148
641663771	490	20.05	52	402	25	365	4.0e-11	63.6	COG3144	Flagellar hook-length control protein FliK	417
641663772	200	30.07	2	154	1	134	8.0e-20	90.3	COG1580	Flagellar basal body-associated protein FliL	159
641663773	334	39.69	5	322	4	321	9.0e-87	314	COG1868	Flagellar motor switch protein FliM	332
641663776	262	55.14	19	261	8	248	3.0e-76	278	COG1338	Flagellar biosynthetic protein FliP	248
641663777	89	47.19	1	89	1	89	5.0e-15	72.9	COG1987	Flagellar biosynthesis protein FliQ	89
641663778	253	40.68	2	237	1	235	6.0e-34	137	COG1684	Flagellar biosynthesis protein FliR	258
641663780	151	40.94	1	124	1	126	2.0e-18	85	COG2893	Phosphotransferase system, mannose/fructose-specific component IIA	143
641663781	89	51.14	1	88	1	88	6.0e-21	92.2	COG1925	Phosphotransferase system, HPr and related phosphotransfer proteins	88
641663782	286	31.47	13	284	3	287	3.0e-41	162	COG3176	Putative hemolysin	292
641663783	603	45.39	7	578	5	562	0.0e+00	575	COG1080	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria)	574
641663792	488	27.53	13	250	2	246	3.0e-19	90.1	COG4584	Transposase	278
641663793	274	31.76	23	252	14	245	3.0e-36	145	COG1484	DNA replication protein DnaC	254
641663795	241	35.47	1	232	13	240	4.0e-42	164	COG0847	DNA polymerase III, epsilon subunit or related 3'-5' exonuclease	243
641663796	112	41.76	1	91	1	87	3.0e-14	70.5	COG0633	Ferredoxin	102
641663797	621	42.86	18	607	4	579	0.0e+00	491	COG0443	Molecular chaperone DnaK (HSP70)	579
641663798	172	34.62	6	156	2	156	1.0e-12	66.5	COG1076	DnaJ-domain-containing proteins 1	174
641663799	110	56.36	2	110	1	110	8.0e-39	151	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
641663800	128	52.05	1	127	5	146	6.0e-36	142	COG0822	NifU homolog involved in Fe-S cluster formation	150
641663801	411	59.28	13	395	2	386	0.0e+00	536	COG1104	Cysteine sulfinate desulfinase/cysteine desulfurase or related enzyme	386
641663802	177	39.86	1	138	1	137	3.0e-33	135	COG1959	DNA-binding transcriptional regulator, IscR family	150
641663803	165	35.95	4	156	2	138	1.0e-29	122	COG0394	Protein-tyrosine-phosphatase	139
641663804	703	65.12	23	689	1	663	0.0e+00	1077	COG0556	Excinuclease UvrABC helicase subunit UvrB	663
641663805	398	59.85	3	398	1	396	0.0e+00	572	COG1448	Aspartate/tyrosine/aromatic aminotransferase	396
641663806	327	31.93	2	325	1	326	1.0e-53	203	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
641663808	582	21.37	53	294	6	239	2.0e-15	77.7	COG1639	HD-like signal output (HDOD) domain, no enzymatic activity	289
641663809	345	44.7	49	344	3	289	1.0e-76	280	COG0167	Dihydroorotate dehydrogenase	310
641663810	220	49.34	1	219	1	226	2.0e-67	248	COG0120	Ribose 5-phosphate isomerase	227
641663814	328	33.13	1	318	5	318	5.0e-51	194	COG2334	Ser/Thr protein kinase RdoA involved in Cpx stress response, MazF antagonist	331
641663816	934	54.65	335	934	1	593	0.0e+00	758	COG0749	DNA polymerase I - 3'-5' exonuclease and polymerase domains	593
641663817	366	44.63	192	364	4	180	1.0e-40	160	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
641663819	335	31.3	1	334	1	342	6.0e-52	198	COG0673	Predicted dehydrogenase	342
641663822	255	30.95	1	249	3	246	2.0e-36	146	COG1192	Cellulose biosynthesis protein BcsQ	259
641663823	421	20.77	72	407	61	388	1.0e-06	48.3	COG2814	Predicted arabinose efflux permease, MFS family	394
641663824	250	35.68	10	250	3	229	2.0e-38	152	COG0830	Urease accessory protein UreF	229
641663825	234	48.23	20	160	19	155	2.0e-25	109	COG2371	Urease accessory protein UreE	155
641663827	313	34.92	20	313	8	271	3.0e-40	159	COG1512	Uncharacterized membrane protein YgcG, contains a TPM-fold domain	271
641663828	204	49.47	4	191	3	183	2.0e-54	205	COG1704	Uncharacterized conserved protein	185
641663829	159	22.48	11	139	2	101	4.0e-08	51.1	COG0607	Rhodanese-related sulfurtransferase	110
641663830	575	74.61	1	575	1	568	0.0e+00	1010	COG0804	Urease alpha subunit	568
641663831	101	58.42	1	101	1	101	1.0e-38	151	COG0832	Urease beta subunit	106
641663833	100	81.82	1	99	1	99	3.0e-43	166	COG0831	Urease gamma subunit	100
641663836	1220	32.19	664	982	23	332	7.0e-46	179	COG0642	Signal transduction histidine kinase	336
641663837	316	45.31	250	313	2	65	3.0e-11	63.1	COG2771	DNA-binding transcriptional regulator, CsgD family	65
641663838	425	33.68	28	401	5	366	3.0e-70	259	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
641663839	528	41.41	232	526	7	297	7.0e-63	235	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
641663840	372	31.86	36	370	7	314	3.0e-49	189	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
641663841	296	65.71	52	296	5	246	7.0e-100	357	COG4674	ABC-type uncharacterized transport system, ATPase component	249
641663842	230	48.44	1	222	3	227	8.0e-80	290	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
641663843	458	32.26	15	446	5	406	2.0e-92	332	COG2081	Predicted flavoprotein YhiN	408
641663846	278	31.79	2	276	5	269	2.0e-43	169	COG0829	Urease accessory protein UreH	269
641663847	72	64.18	6	72	2	67	3.0e-22	96.7	COG1278	Cold shock protein, CspA family	67
641663848	166	37.04	12	114	6	112	1.0e-20	92.3	COG0590	tRNA(Arg) A34 adenosine deaminase TadA	152
641663849	255	35.48	3	248	7	254	8.0e-46	177	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
641663850	272	48.06	3	260	2	243	1.0e-78	286	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
641663851	362	24.34	21	356	5	333	2.0e-21	97.2	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
641663852	411	33.66	14	409	8	406	3.0e-50	193	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
641663853	592	23.34	206	589	27	409	5.0e-34	139	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
641663853	592	50	1	170	5	169	6.0e-48	185	COG3195	2-oxo-4-hydroxy-4-carboxy--5-ureidoimidazoline (OHCU) decarboxylase	176
641663854	336	26.06	25	325	1	267	1.0e-31	130	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
641663855	259	33.64	10	227	1	219	4.0e-31	128	COG1802	DNA-binding transcriptional regulator, GntR family	230
641663856	118	54.24	1	118	8	124	5.0e-39	152	COG2351	5-hydroxyisourate hydrolase (purine catabolism), transthyretin-related family	124
641663857	400	43	1	393	1	399	4.0e-108	385	COG3748	Uncharacterized membrane protein	407
641663858	559	42.67	1	532	4	531	1.0e-117	417	COG1283	Na+/phosphate symporter	533
641663859	537	34.62	188	526	45	408	3.0e-39	157	COG0840	Methyl-accepting chemotaxis protein	408
641663861	502	37.54	220	502	1	282	7.0e-45	175	COG0122	3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase	285
641663861	502	40.11	22	198	10	179	2.0e-44	173	COG2169	Methylphosphotriester-DNA--protein-cysteine methyltransferase (N-terminal fragment of Ada), contains Zn-binding and two AraC-type DNA-binding domains	187
641663862	171	41.76	5	162	1	168	2.0e-37	148	COG0350	O6-methylguanine-DNA--protein-cysteine methyltransferase	168
641663865	324	35.94	22	323	1	302	2.0e-61	229	COG3386	Sugar lactone lactonase YvrE	307
641663866	427	53.02	46	426	1	379	2.0e-93	336	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
641663867	183	33.33	1	153	1	152	3.0e-21	95	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
641663868	328	36.14	3	328	2	330	4.0e-80	291	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
641663870	244	39.17	6	241	2	237	4.0e-39	155	COG2186	DNA-binding transcriptional regulator, FadR family	241
641663871	303	33.11	12	301	6	295	2.0e-48	186	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
641663872	444	28.26	11	412	5	370	8.0e-51	194	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
641663873	479	47.28	2	478	1	468	3.0e-127	449	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
641663874	317	35.28	3	309	5	312	8.0e-60	224	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
641663875	314	38.92	1	306	1	316	5.0e-80	291	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
641663876	265	37.01	1	251	3	254	3.0e-52	198	COG3836	2-keto-3-deoxy-L-rhamnonate aldolase RhmA	255
641663877	299	55.59	1	284	1	286	9.0e-79	287	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
641663878	1017	35.2	587	1015	104	498	2.0e-83	304	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
641663879	651	40.64	16	650	4	638	0.0e+00	574	COG0323	DNA mismatch repair ATPase MutL	638
641663880	372	19.17	19	371	2	361	1.0e-19	90.9	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
641663881	219	34.34	15	211	2	199	2.0e-34	138	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
641663883	523	34.24	258	514	13	231	4.0e-50	192	COG0860	N-acetylmuramoyl-L-alanine amidase	231
641663884	160	42.95	11	159	6	147	1.0e-33	135	COG0802	tRNA A37 threonylcarbamoyladenosine biosynthesis protein TsaE	149
641663885	361	47.01	10	358	1	337	4.0e-90	325	COG1600	Epoxyqueuosine reductase  QueG (queuosine biosynthesis)	337
641663886	435	61.1	13	431	8	421	0.0e+00	527	COG2379	Glycerate-2-kinase	422
641663887	301	50.18	7	289	2	286	1.0e-86	313	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
641663888	259	61.26	1	253	1	253	2.0e-105	375	COG3622	Hydroxypyruvate isomerase	260
641663889	596	75.86	1	584	1	582	0.0e+00	1000	COG3960	Glyoxylate carboligase	592
641663892	412	27.27	332	411	7	94	7.0e-07	48.9	COG0633	Ferredoxin	102
641663892	412	32.68	51	355	1	266	1.0e-47	184	COG1018	Ferredoxin-NADP reductase	266
641663894	454	37.33	1	432	1	413	5.0e-73	268	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
641663895	490	42.47	1	483	1	451	4.0e-101	362	COG2233	Xanthine/uracil permease	451
641663896	406	44.53	5	403	4	404	2.0e-108	386	COG3748	Uncharacterized membrane protein	407
641663897	305	33	7	297	8	307	3.0e-29	122	COG0679	Predicted permease	311
641663898	268	30.82	58	216	21	178	3.0e-21	95.8	COG2091	Phosphopantetheinyl transferase	223
641663899	325	39.42	6	317	5	312	4.0e-66	245	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
641663900	286	54.51	1	286	13	300	4.0e-97	347	COG4974	Site-specific recombinase XerD	300
641663901	250	43.97	11	242	14	215	5.0e-50	191	COG0765	ABC-type amino acid transport system, permease component	222
641663902	283	35.41	31	280	17	273	2.0e-35	142	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
641663907	96	38.67	1	75	1	71	2.0e-12	63.7	COG1343	CRISPR/Cas system-associated endoribonuclease Cas2	89
641663908	343	35.38	3	342	2	327	6.0e-63	234	COG1518	CRISPR/Cas system-associated endonuclease Cas1	327
641663909	212	25.81	8	193	16	190	4.0e-19	88.5	COG1468	CRISPR/Cas system-associated exonuclease Cas4, RecB family	190
641663912	302	34.6	3	286	4	269	8.0e-41	161	COG3649	CRISPR/Cas system type I-B associated protein Csh2, Cas7 group, RAMP superfamily	283
641663917	339	40.65	25	324	7	286	1.0e-66	246	COG1281	Redox-regulated molecular chaperone, HSP33 family	286
641663918	174	50.57	1	174	2	175	2.0e-55	208	COG0663	Carbonic anhydrase or acetyltransferase, isoleucine patch superfamily	176
641663919	277	52.94	1	272	3	263	1.0e-80	293	COG2833	Uncharacterized conserved protein, contains ferritin-like DUF455 domain	268
641663921	200	38.69	1	197	3	201	6.0e-33	133	COG2095	Small neutral amino acid transporter SnatA, MarC family	203
641663924	529	40.69	54	505	1	459	1.0e-88	320	COG0277	FAD/FMN-containing dehydrogenase	459
641663925	375	24.02	4	375	35	459	2.0e-27	116	COG0277	FAD/FMN-containing dehydrogenase	459
641663926	418	29.03	21	416	7	388	2.0e-59	223	COG0247	Fe-S oxidoreductase	388
641663927	94	42.7	5	93	25	113	5.0e-13	66.1	COG2919	Cell division protein FtsB	117
641663928	427	68.31	1	426	1	423	0.0e+00	658	COG0148	Enolase	423
641663929	285	59.43	1	281	5	279	2.0e-113	402	COG2877	3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase	279
641663930	563	59.28	2	554	1	529	0.0e+00	835	COG0504	CTP synthase (UTP-ammonia lyase)	533
641663931	286	49.48	1	285	1	281	4.0e-92	331	COG0414	Panthothenate synthetase	285
641663932	289	49.45	16	289	1	267	3.0e-84	305	COG0413	Ketopantoate hydroxymethyltransferase	268
641663933	411	20.78	27	384	35	381	3.0e-12	66.9	COG5653	Acetyltransferase involved in cellulose biosynthesis, CelD/BcsL family	406
641663934	275	55.73	1	253	1	247	3.0e-92	331	COG3484	Predicted proteasome-type protease	255
641663935	886	44.75	1	869	9	843	0.0e+00	852	COG0249	DNA mismatch repair ATPase MutS	843
641663937	433	35.25	46	428	1	368	8.0e-32	131	COG3174	Uncharacterized membrane protein, DUF4010 family	371
641663938	168	34.4	17	141	6	126	1.0e-12	66.1	COG1846	DNA-binding transcriptional regulator, MarR family	126
641663939	255	39.39	1	231	1	224	8.0e-43	167	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
641663940	262	50.94	4	262	16	280	3.0e-81	294	COG0447	1,4-Dihydroxy-2-naphthoyl-CoA synthase	282
641663941	389	35.51	7	379	5	384	4.0e-68	252	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
641663942	547	36.55	17	545	4	528	1.0e-101	364	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
641663943	330	37.5	11	328	1	318	3.0e-61	229	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
641663944	258	45.74	1	255	2	257	1.0e-54	206	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
641663945	386	46.02	5	383	6	387	2.0e-88	319	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
641663946	561	31.74	16	474	2	396	3.0e-70	259	COG0644	Dehydrogenase (flavoprotein)	396
641663947	394	36.22	17	394	1	392	2.0e-79	290	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
641663948	249	48.85	1	249	1	260	3.0e-70	258	COG2086	Electron transfer flavoprotein, alpha and beta subunits	260
641663949	308	53.97	1	308	1	310	1.0e-80	293	COG2025	Electron transfer flavoprotein, alpha subunit	313
641663950	261	36.18	12	256	14	256	1.0e-38	153	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
641663951	504	46.74	8	297	5	295	2.0e-84	307	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
641663952	401	42.05	5	401	4	392	2.0e-82	299	COG0183	Acetyl-CoA acetyltransferase	392
641663953	310	29.73	187	297	15	125	3.0e-16	79.5	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
641663954	287	37.94	15	260	1	250	1.0e-40	160	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
641663955	567	16.84	1	566	2	551	5.0e-35	142	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
641663957	265	42.35	3	249	7	250	5.0e-42	165	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
641663958	282	33.1	1	279	6	291	1.0e-36	146	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
641663959	333	34.42	8	309	7	310	4.0e-33	135	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
641663960	239	38.06	5	237	4	250	4.0e-62	231	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
641663961	232	43.69	3	220	2	223	1.0e-63	236	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
641663962	396	31.28	22	373	1	358	2.0e-44	173	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
641663963	195	17.95	10	164	13	166	1.0e-07	50	COG3945	Hemerythrin-like domain	189
641663965	178	39.44	9	175	4	183	2.0e-36	145	COG3658	Cytochrome b	192
641663966	523	49.03	1	513	1	513	0.0e+00	548	COG4670	Acyl CoA:acetate/3-ketoacid CoA transferase	527
641663967	386	41.67	1	381	1	393	1.0e-79	290	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
641663968	380	32.26	18	376	1	365	1.0e-40	161	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
641663969	368	32.96	24	368	1	342	2.0e-47	183	COG0673	Predicted dehydrogenase	342
641663970	270	19.13	6	266	6	272	4.0e-12	65.2	COG1082	Sugar phosphate isomerase/epimerase	274
641663971	267	45.2	5	250	7	251	9.0e-37	147	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
641663972	431	48.08	6	263	1	259	5.0e-73	268	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
641663973	252	45.41	9	235	6	230	1.0e-58	219	COG0565	tRNA C32,U32 (ribose-2'-O)-methylase TrmJ or a related methyltransferase	242
641663974	259	58.58	1	169	3	170	1.0e-60	226	COG1045	Serine acetyltransferase	194
641663975	206	45	7	185	2	169	1.0e-43	170	COG0521	Molybdopterin biosynthesis enzyme MoaB	169
641663976	217	35.98	13	200	4	182	1.0e-32	133	COG3028	Ribosomal 50S subunit-associated protein YjgA (function unknown), DUF615 family	187
641663977	474	38.73	35	473	2	453	1.0e-85	310	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
641663978	360	54.27	1	357	1	363	7.0e-125	440	COG4663	TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component	363
641663980	263	31.68	3	257	1	249	7.0e-28	117	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
641663982	327	45.29	3	326	2	325	1.0e-76	279	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
641663983	662	21.54	20	652	10	691	4.0e-37	150	COG4771	Outer membrane receptor for ferrienterochelin and colicins	699
641663987	289	27.86	23	285	19	280	1.0e-23	103	COG5473	Uncharacterized membrane protein	290
641663988	170	41.56	14	164	13	156	4.0e-28	117	COG0597	Lipoprotein signal peptidase	167
641663989	295	49.83	2	295	11	298	4.0e-98	351	COG4989	Predicted oxidoreductase	298
641663990	998	42.6	36	992	2	933	0.0e+00	1099	COG0060	Isoleucyl-tRNA synthetase	933
641663991	345	41.41	1	325	1	303	2.0e-81	296	COG0196	FAD synthase	304
641663993	379	28.94	1	371	1	386	1.0e-38	154	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
641663994	379	34.43	1	379	1	388	5.0e-58	218	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
641663996	168	53.99	7	168	4	165	4.0e-42	164	COG1666	Uncharacterized conserved protein YajQ, UPF0234 family	165
641663997	344	32.06	7	344	1	286	2.0e-69	256	COG0812	UDP-N-acetylenolpyruvoylglucosamine reductase	291
641663998	409	33.88	29	271	4	223	1.0e-37	151	COG0797	Rare lipoprotein A, peptidoglycan hydrolase digesting "naked" glycans, contains C-terminal SPOR domain	233
641663999	367	39.62	4	363	3	358	1.0e-82	300	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
641664000	254	51.74	1	253	1	259	2.0e-87	315	COG0708	Exonuclease III	261
641664002	493	29.44	1	448	1	461	2.0e-67	250	COG0415	Deoxyribodipyrimidine photolyase	461
641664004	513	50.1	7	510	5	501	0.0e+00	557	COG3046	Uncharacterized protein related to deoxyribodipyrimidine photolyase	505
641664005	55	60.42	7	54	2	49	1.0e-07	48.2	COG4338	Uncharacterized protein	54
641664007	153	30.39	46	146	7	108	4.0e-14	70.7	COG0607	Rhodanese-related sulfurtransferase	110
641664008	247	24.76	27	226	2	207	3.0e-21	95.7	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
641664009	167	23.35	3	165	32	195	2.0e-08	51.8	COG1515	Deoxyinosine 3'endonuclease (endonuclease V)	212
641664010	188	30.07	29	176	17	164	1.0e-07	49.9	COG3161	4-hydroxybenzoate synthetase (chorismate-pyruvate lyase)	174
641664011	335	43.52	20	320	3	294	9.0e-67	247	COG1230	Co/Zn/Cd efflux system component	296
641664012	322	17.98	7	322	2	354	1.0e-14	74.2	COG3203	Outer membrane protein (porin)	354
641664013	166	49.7	3	163	1	167	2.0e-43	168	COG0262	Dihydrofolate reductase	167
641664014	282	60.89	14	282	5	268	2.0e-111	395	COG0207	Thymidylate synthase	268
641664016	601	39.41	15	595	1	567	9.0e-124	437	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
641664019	481	25.54	82	473	43	457	9.0e-20	91.8	COG1538	Outer membrane protein TolC	457
641664020	470	25.99	72	396	31	348	9.0e-35	141	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
641664021	171	38.41	4	163	5	156	1.0e-24	105	COG4454	Uncharacterized copper-binding protein, cupredoxin-like subfamily	158
641664022	169	48.67	21	169	2	147	5.0e-42	163	COG3019	Uncharacterized conserved protein	149
641664023	249	31.98	1	245	4	237	4.0e-26	112	COG5343	Anti-sigma-K factor RskA	240
641664024	188	34.27	11	188	3	176	2.0e-22	99	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641664026	548	59.09	7	547	4	532	0.0e+00	680	COG4172	ABC-type microcin C transport system, duplicated ATPase component YejF	534
641664027	371	55.82	37	371	7	340	3.0e-114	405	COG4239	ABC-type microcin C transport system, permease component YejE	341
641664028	345	57.18	1	342	1	362	0.0e+00	484	COG4174	ABC-type microcin C transport system, permease component YejB	364
641664029	140	29.85	4	134	6	133	1.0e-13	69.1	COG2445	Uncharacterized conserved protein YutE, UPF0331/DUF86 family	138
641664031	641	26.95	20	636	9	557	1.0e-59	224	COG4166	ABC-type oligopeptide transport system, periplasmic component	562
641664032	229	21.83	2	229	29	257	7.0e-28	117	COG0725	ABC-type molybdate transport system, periplasmic component	258
641664033	409	33.7	35	402	19	354	6.0e-50	191	COG5621	Predicted secreted hydrolase	354
641664036	853	23.65	27	400	26	407	5.0e-15	76.8	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
641664038	231	45	13	227	1	218	4.0e-65	241	COG1136	ABC-type lipoprotein export system, ATPase component	226
641664039	328	48.05	15	322	6	304	6.0e-86	311	COG0324	tRNA A37 N6-isopentenylltransferase MiaA	308
641664040	415	22.93	45	406	36	386	7.0e-17	82.2	COG2814	Predicted arabinose efflux permease, MFS family	394
641664044	197	20.1	6	191	1	199	1.0e-13	69.6	COG0778	Nitroreductase	207
641664045	252	23.74	7	252	3	258	2.0e-07	50	COG0730	Uncharacterized membrane protein YfcA	258
641664046	263	35.6	14	260	13	257	9.0e-33	134	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
641664047	510	39.85	1	506	7	527	1.0e-111	397	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
641664048	575	36.03	181	513	51	408	1.0e-46	181	COG0840	Methyl-accepting chemotaxis protein	408
641664050	605	38.85	1	392	2	395	5.0e-64	239	COG0475	Kef-type K+ transport system, membrane component KefB	397
641664051	214	36.41	11	183	2	184	7.0e-35	140	COG2249	Putative NADPH-quinone reductase (modulator of drug activity B)	189
641664052	224	25	1	221	2	250	2.0e-15	76.4	COG1192	Cellulose biosynthesis protein BcsQ	259
641664053	273	33.86	1	253	1	206	1.0e-33	137	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
641664054	468	29.97	21	325	43	334	2.0e-38	153	COG0642	Signal transduction histidine kinase	336
641664055	296	42.36	1	286	6	284	9.0e-70	257	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
641664056	68	32.2	1	59	8	60	2.0e-07	47.3	COG4391	Uncharacterized conserved protein, contains Zn-finger domain	62
641664057	295	54.58	1	295	1	287	8.0e-116	409	COG0788	Formyltetrahydrofolate hydrolase	287
641664058	138	24.59	6	123	14	132	1.0e-06	45.3	COG4319	Ketosteroid isomerase homolog	137
641664059	379	36.16	11	357	4	337	3.0e-75	275	COG0429	Predicted hydrolase of the alpha/beta-hydrolase fold	345
641664061	174	39.66	49	158	11	126	8.0e-13	67	COG3245	Cytochrome c5	126
641664064	824	38.4	4	820	8	861	0.0e+00	612	COG4096	Type I site-specific restriction endonuclease, part of a restriction-modification system	875
641664065	489	30.66	1	486	4	486	1.0e-69	257	COG0286	Type I restriction-modification system, DNA methylase subunit	489
641664070	320	35.31	1	316	1	316	2.0e-44	173	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
641664071	344	25.47	4	313	3	296	4.0e-25	109	COG0583	DNA-binding transcriptional regulator, LysR family	297
641664076	239	30.58	13	133	5	118	3.0e-11	62.3	COG2863	Cytochrome c553	121
641664079	121	40.18	1	111	5	116	1.0e-15	75.2	COG1380	Putative effector of murein hydrolase LrgA, UPF0299 family	128
641664080	238	41.92	10	238	2	229	7.0e-47	180	COG1346	Putative effector of murein hydrolase	230
641664081	321	26.61	11	239	28	247	8.0e-24	104	COG1191	DNA-directed RNA polymerase specialized sigma subunit	247
641664084	636	32.75	171	555	115	472	9.0e-15	75.8	COG1404	Serine protease, subtilisin family	508
641664085	441	33.86	60	439	8	378	1.0e-62	234	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
641664086	165	30.77	1	156	5	158	1.0e-06	45.7	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
641664087	343	23.34	1	340	1	332	5.0e-38	151	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
641664088	322	36.8	1	260	1	265	6.0e-52	198	COG1018	Ferredoxin-NADP reductase	266
641664089	351	27.97	1	342	22	361	2.0e-54	206	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
641664090	246	33.01	26	234	21	216	6.0e-24	104	COG1802	DNA-binding transcriptional regulator, GntR family	230
641664092	202	54.64	8	190	1	182	1.0e-64	239	COG3005	Tetraheme cytochrome c subunit of nitrate or TMAO reductase	190
641664093	233	57.92	18	195	4	184	4.0e-65	241	COG3005	Tetraheme cytochrome c subunit of nitrate or TMAO reductase	190
641664094	161	35.9	5	160	2	153	6.0e-38	150	COG3043	Nitrate reductase cytochrome c-type subunit	155
641664097	851	30.72	2	851	1	764	0.0e+00	557	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
641664099	483	32.55	4	464	3	452	2.0e-90	326	COG2710	Nitrogenase molybdenum-iron protein, alpha and beta chains	456
641664101	153	30.46	1	147	2	152	5.0e-17	80.7	COG0680	Ni,Fe-hydrogenase maturation factor	160
641664102	509	32.92	1	500	1	533	3.0e-97	349	COG0374	Ni,Fe-hydrogenase I large subunit	545
641664103	313	27.41	4	308	51	353	6.0e-56	211	COG1740	Ni,Fe-hydrogenase I small subunit	355
641664104	457	29.91	8	431	24	439	1.0e-70	261	COG2710	Nitrogenase molybdenum-iron protein, alpha and beta chains	456
641664107	66	42.62	1	61	5	65	1.0e-09	54.7	COG5420	Uncharacterized protein	71
641664110	253	33.33	10	252	12	255	4.0e-39	155	COG0725	ABC-type molybdate transport system, periplasmic component	258
641664111	232	46.54	4	220	2	218	1.0e-56	213	COG4149	ABC-type molybdate transport system, permease component	225
641664112	374	46.45	11	374	1	352	2.0e-103	369	COG4148	ABC-type molybdate transport system, ATPase component	352
641664114	408	60.67	9	392	1	386	0.0e+00	548	COG1104	Cysteine sulfinate desulfinase/cysteine desulfurase or related enzyme	386
641664115	142	51.72	1	126	5	145	7.0e-36	142	COG0822	NifU homolog involved in Fe-S cluster formation	150
641664116	139	52.29	31	139	2	110	3.0e-34	137	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
641664117	107	50.93	1	107	3	110	3.0e-35	139	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
641664118	636	44.86	18	593	4	567	0.0e+00	496	COG0443	Molecular chaperone DnaK (HSP70)	579
641664119	127	40.86	30	120	12	102	1.0e-14	72	COG0633	Ferredoxin	102
641664120	384	41.53	9	377	3	379	3.0e-89	322	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
641664122	283	48.15	1	268	1	255	3.0e-67	248	COG2086	Electron transfer flavoprotein, alpha and beta subunits	260
641664123	374	42.07	38	365	1	313	5.0e-90	324	COG2025	Electron transfer flavoprotein, alpha subunit	313
641664124	434	31.11	3	432	2	395	3.0e-65	242	COG0644	Dehydrogenase (flavoprotein)	396
641664125	98	44.68	5	98	7	99	1.0e-26	110	COG2440	Ferredoxin-like protein FixX	99
641664126	593	34.78	5	593	19	550	3.0e-127	449	COG3604	Transcriptional regulator containing GAF, AAA-type ATPase, and DNA-binding Fis domains	550
641664127	265	42.61	5	230	3	229	9.0e-48	183	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
641664130	465	27.38	1	421	17	458	3.0e-32	133	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
641664131	300	33.66	98	298	28	227	2.0e-27	116	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
641664136	316	27.13	12	261	4	256	2.0e-40	160	COG1442	Lipopolysaccharide biosynthesis protein, LPS:glycosyltransferase	325
641664139	376	38.2	5	367	4	371	3.0e-88	318	COG0381	UDP-N-acetylglucosamine 2-epimerase	383
641664142	324	29.18	1	301	3	291	1.0e-40	160	COG1216	Glycosyltransferase, GT2 family	305
641664143	625	29.73	1	616	1	538	5.0e-103	368	COG0367	Asparagine synthetase B (glutamine-hydrolyzing)	542
641664146	860	35.53	520	814	2	295	7.0e-50	192	COG1817	Predicted glycosyltransferase	346
641664147	392	42.78	1	378	5	372	7.0e-103	367	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
641664148	325	38.08	7	321	2	314	4.0e-49	188	COG0451	Nucleoside-diphosphate-sugar epimerase	314
641664149	403	50	193	403	37	226	7.0e-63	234	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
641664151	352	29.91	11	334	4	331	4.0e-43	168	COG0673	Predicted dehydrogenase	342
641664152	420	46.77	2	363	1	370	7.0e-111	394	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
641664154	205	44.88	1	204	5	209	1.0e-44	172	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
641664156	211	42.86	3	211	1	210	6.0e-54	203	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
641664160	134	32.38	4	107	3	107	1.0e-19	89.1	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
641664166	391	43.34	3	383	1	383	3.0e-105	375	COG1104	Cysteine sulfinate desulfinase/cysteine desulfurase or related enzyme	386
641664167	72	62.69	1	67	1	66	6.0e-20	88.9	COG5554	Nitrogen fixation protein	69
641664169	401	36.53	21	389	2	369	3.0e-75	275	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
641664171	101	31.03	8	94	12	96	1.0e-08	51.2	COG0633	Ferredoxin	102
641664172	396	23.71	3	396	9	449	3.0e-19	90	COG1231	Monoamine oxidase	450
641664178	593	46.05	1	591	6	587	0.0e+00	546	COG1331	Uncharacterized conserved protein YyaL, SSP411 family, contains thoiredoxin and six-hairpin glycosidase-like domains	667
641664184	293	67.64	4	277	1	274	8.0e-118	416	COG1348	Nitrogenase subunit NifH, an ATPase	278
641664185	485	35.12	25	484	1	448	1.0e-104	373	COG2710	Nitrogenase molybdenum-iron protein, alpha and beta chains	456
641664186	519	29.39	35	515	3	453	1.0e-87	317	COG2710	Nitrogenase molybdenum-iron protein, alpha and beta chains	456
641664189	172	37.18	6	156	2	156	8.0e-15	73.5	COG1076	DnaJ-domain-containing proteins 1	174
641664190	281	29.17	40	277	2	240	5.0e-40	158	COG1414	DNA-binding transcriptional regulator, IclR family	246
641664191	271	32.36	1	267	10	283	8.0e-42	164	COG0169	Shikimate 5-dehydrogenase	283
641664192	338	40.95	1	337	2	332	6.0e-90	324	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
641664193	284	39.71	1	269	2	275	1.0e-29	123	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
641664194	146	37.82	18	136	1	119	1.0e-25	108	COG1733	DNA-binding transcriptional regulator, HxlR family	120
641664195	283	53.11	30	270	5	242	4.0e-74	271	COG0007	Uroporphyrinogen-III methylase (siroheme synthase)	244
641664196	573	17.86	55	164	41	150	9.0e-07	49.2	COG2010	Cytochrome c, mono- and diheme variants	150
641664199	338	21.9	163	296	2	130	1.0e-08	54.7	COG1522	DNA-binding transcriptional regulator, Lrp family	154
641664200	163	20.63	1	123	5	127	5.0e-08	50.8	COG1522	DNA-binding transcriptional regulator, Lrp family	154
641664201	160	19.5	1	157	4	154	3.0e-13	67.8	COG1522	DNA-binding transcriptional regulator, Lrp family	154
641664202	418	32.71	21	390	5	347	5.0e-55	208	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
641664203	945	32.98	512	795	62	335	2.0e-38	155	COG0642	Signal transduction histidine kinase	336
641664208	252	25.32	11	243	1	213	3.0e-25	109	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
641664209	225	59.9	20	225	10	216	9.0e-74	270	COG4380	Uncharacterized protein	216
641664210	126	53.85	5	121	2	117	1.0e-32	132	COG4259	Uncharacterized protein	121
641664211	225	50.85	5	225	3	238	5.0e-57	214	COG1462	Curli biogenesis system outer membrane secretion channel CsgG	252
641664212	151	21.71	2	147	5	152	2.0e-08	52.2	COG0680	Ni,Fe-hydrogenase maturation factor	160
641664213	504	41.1	16	470	4	432	8.0e-114	404	COG3259	Coenzyme F420-reducing hydrogenase, alpha subunit	441
641664216	627	32.88	36	181	14	158	5.0e-26	113	COG1905	NADH:ubiquinone oxidoreductase 24 kD subunit (chain E)	160
641664216	627	43.64	216	592	25	420	4.0e-119	422	COG1894	NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F)	424
641664217	364	46.2	1	362	9	360	3.0e-94	338	COG3437	Response regulator c-di-GMP phosphodiesterase, RpfG family, contains REC and HD-GYP domains	360
641664218	1135	35.91	621	878	85	331	9.0e-41	163	COG0642	Signal transduction histidine kinase	336
641664219	618	35.64	1	618	7	637	8.0e-105	375	COG4548	Nitric oxide reductase activation protein	637
641664220	344	19.81	9	309	4	280	8.0e-14	71.6	COG0348	Polyferredoxin	386
641664221	277	22.61	12	274	22	300	4.0e-28	118	COG0714	MoxR-like ATPase	329
641664224	336	37.87	5	336	5	312	5.0e-73	267	COG0826	Collagenase-like protease, PrtC family	347
641664225	317	24.84	10	313	2	301	1.0e-35	143	COG0826	Collagenase-like protease, PrtC family	347
641664227	390	43.52	10	386	5	373	6.0e-83	301	COG3448	CBS-domain-containing membrane protein	382
641664228	89	43.01	1	89	3	95	2.0e-20	90.5	COG4309	Uncharacterized conserved protein, DUF2249 family	98
641664229	399	37.08	14	398	6	396	3.0e-53	202	COG3213	Uncharacterized protein involved in response to NO	396
641664230	165	43.51	1	130	1	131	3.0e-28	118	COG1959	DNA-binding transcriptional regulator, IscR family	150
641664231	481	31.43	28	446	1	384	3.0e-72	266	COG0348	Polyferredoxin	386
641664232	191	38.92	28	191	11	173	4.0e-37	147	COG4314	Nitrous oxide reductase accessory protein NosL	176
641664233	271	26.55	4	270	2	273	1.0e-15	77.5	COG1277	ABC-type transport system involved in multi-copper enzyme maturation, permease component	278
641664234	338	35.71	30	331	3	287	4.0e-68	251	COG1131	ABC-type multidrug transport system, ATPase component	293
641664235	400	43.42	13	389	30	408	2.0e-125	442	COG3420	Nitrous oxidase accessory protein NosD, contains tandem CASH domains	408
641664236	886	40.53	13	483	5	478	2.0e-124	440	COG3901	Regulator of nitric oxide reductase transcription	482
641664237	644	55.54	15	644	10	637	0.0e+00	862	COG4263	Nitrous oxide reductase	637
641664238	369	36.71	23	360	5	337	8.0e-69	254	COG1477	Thiamine biosynthesis lipoprotein ApbE	337
641664239	434	25.37	33	432	15	394	4.0e-09	56.4	COG3213	Uncharacterized protein involved in response to NO	396
641664240	105	40.19	1	105	5	110	1.0e-19	88.4	COG2151	Metal-sulfur cluster biosynthetic enzyme	111
641664242	101	44.66	2	101	4	106	2.0e-14	70.9	COG4654	Cytochrome c551/c552	110
641664244	560	52.93	4	557	10	572	0.0e+00	711	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
641664245	308	33.22	2	300	1	297	5.0e-26	112	COG0583	DNA-binding transcriptional regulator, LysR family	297
641664246	277	40.48	1	276	5	277	2.0e-60	226	COG0682	Prolipoprotein diacylglyceryltransferase	287
641664247	357	52.89	9	354	1	334	1.0e-116	413	COG0533	tRNA A37 threonylcarbamoyltransferase TsaD	342
641664248	426	25.85	21	399	1	366	1.0e-40	161	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
641664249	388	35.92	22	387	26	390	8.0e-80	291	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
641664250	87	55.17	1	87	3	89	2.0e-24	104	COG0184	Ribosomal protein S15P/S13E	89
641664251	767	62.82	3	696	1	692	0.0e+00	982	COG1185	Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase)	692
641664252	328	42.9	1	326	1	324	5.0e-71	261	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
641664253	248	49.59	5	247	3	247	2.0e-79	288	COG0149	Triosephosphate isomerase	251
641664254	133	55.13	4	81	1	77	2.0e-14	71.4	COG1314	Preprotein translocase subunit SecG	86
641664256	119	56.3	1	119	3	121	2.0e-33	134	COG0838	NADH:ubiquinone oxidoreductase subunit 3 (chain A)	123
641664257	158	70.7	2	158	12	168	1.0e-75	275	COG0377	NADH:ubiquinone oxidoreductase 20 kD subunit (chhain B) or related Fe-S oxidoreductase	194
641664258	199	46.07	1	178	2	169	1.0e-43	169	COG0852	NADH:ubiquinone oxidoreductase 27 kD subunit (chain C)	176
641664259	417	58.75	1	417	9	398	0.0e+00	607	COG0649	NADH:ubiquinone oxidoreductase 49 kD subunit (chain D)	398
641664260	175	43.48	9	169	1	158	8.0e-41	160	COG1905	NADH:ubiquinone oxidoreductase 24 kD subunit (chain E)	160
641664261	452	60.23	17	445	1	424	0.0e+00	624	COG1894	NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F)	424
641664262	770	37.89	1	729	1	693	0.0e+00	585	COG1034	NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)	693
641664263	352	51.04	14	349	6	332	1.0e-97	349	COG1005	NADH:ubiquinone oxidoreductase subunit 1 (chain H)	332
641664264	165	45.73	7	165	3	161	1.0e-44	172	COG1143	Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)	172
641664265	216	41.42	1	169	1	166	1.0e-25	109	COG0839	NADH:ubiquinone oxidoreductase subunit 6 (chain J)	166
641664266	101	62.38	1	101	1	100	9.0e-23	98.2	COG0713	NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K)	100
641664267	666	43.05	9	660	1	606	0.0e+00	485	COG1009	NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit	606
641664268	490	50.61	4	490	6	491	0.0e+00	519	COG1008	NADH:ubiquinone oxidoreductase subunit 4 (chain M)	497
641664269	493	42.77	2	491	1	475	2.0e-93	336	COG1007	NADH:ubiquinone oxidoreductase subunit 2 (chain N)	475
641664270	208	22.22	47	193	2	161	7.0e-06	44.2	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
641664271	160	39.47	1	152	1	137	3.0e-34	137	COG5319	Uncharacterized protein	142
641664272	472	39.06	11	472	1	456	6.0e-84	304	COG0277	FAD/FMN-containing dehydrogenase	459
641664273	124	40.17	4	116	15	130	7.0e-13	66.1	COG3308	Uncharacterized membrane protein	131
641664274	424	31.6	35	293	15	282	4.0e-36	145	COG1295	Uncharacterized membrane protein, BrkB/YihY/UPF0761 family (not an RNase)	303
641664275	543	36.31	196	517	62	408	4.0e-52	199	COG0840	Methyl-accepting chemotaxis protein	408
641664276	287	27.21	8	286	1	279	1.0e-12	67.4	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
641664277	452	55.92	2	432	1	426	0.0e+00	584	COG2873	O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent	426
641664279	187	44.14	41	185	19	163	5.0e-36	144	COG0835	Chemotaxis signal transduction protein	165
641664280	385	55.41	2	364	1	369	0.0e+00	507	COG0082	Chorismate synthase	369
641664281	370	45.14	3	370	1	348	9.0e-86	310	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
641664282	160	28.95	8	157	7	156	6.0e-22	96.8	COG1871	Chemotaxis receptor (MCP) glutamine deamidase CheD	164
641664283	266	38.72	8	262	4	263	7.0e-57	213	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
641664284	183	32.26	22	176	17	165	3.0e-26	111	COG0835	Chemotaxis signal transduction protein	165
641664285	890	34.44	498	821	46	408	4.0e-46	180	COG0840	Methyl-accepting chemotaxis protein	408
641664286	1019	33.16	605	948	27	408	3.0e-46	181	COG0840	Methyl-accepting chemotaxis protein	408
641664287	853	34.27	542	823	89	408	1.0e-42	169	COG0840	Methyl-accepting chemotaxis protein	408
641664288	750	36.65	2	734	1	709	0.0e+00	519	COG0643	Chemotaxis protein histidine kinase CheA	716
641664289	110	30.12	14	96	19	101	3.0e-08	50.4	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
641664293	413	30.66	89	412	60	408	1.0e-39	157	COG0840	Methyl-accepting chemotaxis protein	408
641664294	681	50.84	490	666	2	179	1.0e-39	158	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
641664299	234	43.69	22	226	3	204	2.0e-46	178	COG4133	ABC-type transport system involved in cytochrome c biogenesis, ATPase component	209
641664300	237	51.83	20	237	4	221	2.0e-39	155	COG2386	ABC-type transport system involved in cytochrome c biogenesis, permease component	221
641664301	247	40.25	9	243	41	276	3.0e-30	125	COG0755	ABC-type transport system involved in cytochrome c biogenesis, permease component	281
641664303	153	53.68	2	134	3	138	5.0e-39	153	COG2332	Cytochrome c-type biogenesis protein CcmE	153
641664304	660	57.05	1	643	1	641	0.0e+00	648	COG1138	Cytochrome c biogenesis factor	648
641664305	176	25	30	154	2	127	2.0e-09	55.7	COG0526	Thiol-disulfide isomerase or thioredoxin	127
641664306	179	44.08	1	152	2	149	2.0e-35	141	COG3088	Cytochrome c-type biogenesis protein CcmH/NrfF	153
641664307	443	26.74	4	291	36	275	1.0e-19	91.2	COG4235	Cytochrome c-type biogenesis protein CcmH/NrfG	287
641664308	438	28.89	172	432	5	251	3.0e-25	109	COG0492	Thioredoxin reductase	305
641664309	241	24.75	1	199	2	190	8.0e-18	84.2	COG0400	Predicted esterase	207
641664310	364	40.17	9	355	1	342	5.0e-102	364	COG2008	Threonine aldolase	342
641664311	326	39.06	1	319	14	318	3.0e-70	259	COG2826	Transposase and inactivated derivatives, IS30 family	318
641664312	337	34.09	7	314	2	260	2.0e-45	176	COG1975	Xanthine and CO dehydrogenase maturation factor, XdhC/CoxF family	278
641664313	972	56.76	10	450	1	445	0.0e+00	570	COG0403	Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain	450
641664313	972	60.96	479	943	29	496	0.0e+00	693	COG1003	Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain	496
641664314	124	59.17	5	123	11	130	1.0e-36	144	COG0509	Glycine cleavage system H protein (lipoate-binding)	131
641664315	374	40.89	3	374	1	377	2.0e-93	336	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
641664316	337	41.67	2	298	3	302	2.0e-72	266	COG2974	DNA recombination-dependent growth factor C	303
641664317	430	22.52	12	396	1	390	4.0e-31	129	COG0420	DNA repair exonuclease SbcCD nuclease subunit	390
641664318	1155	19.02	372	1137	211	969	8.0e-27	116	COG4717	Uncharacterized protein YhaN	984
641664319	128	47.62	3	128	4	129	6.0e-36	142	COG3744	PIN domain nuclease, a component of toxin-antitoxin system (PIN domain)	130
641664320	75	44	1	75	2	75	2.0e-08	50.8	COG4118	Antitoxin component of toxin-antitoxin stability system, DNA-binding transcriptional repressor	84
641664321	390	56.22	4	389	1	365	0.0e+00	513	COG0343	Queuine/archaeosine tRNA-ribosyltransferase	372
641664323	767	25.36	31	767	26	750	2.0e-79	290	COG4774	Outer membrane receptor for monomeric catechols	750
641664324	231	53.25	1	231	3	229	3.0e-74	271	COG3128	Predicted 2-oxoglutarate- and Fe(II)-dependent dioxygenase YbiX	229
641664325	251	23.96	45	241	17	233	5.0e-06	45.1	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
641664326	266	41.15	30	238	4	210	2.0e-36	145	COG0811	Biopolymer transport protein ExbB/TolQ	216
641664327	139	38.06	4	137	2	135	2.0e-30	124	COG0848	Biopolymer transport protein ExbD	137
641664328	219	35.81	1	215	1	208	2.0e-37	149	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
641664329	777	29.41	309	629	9	325	9.0e-37	149	COG0642	Signal transduction histidine kinase	336
641664330	133	32.77	10	128	1	103	4.0e-06	43.9	COG4654	Cytochrome c551/c552	110
641664331	356	55.24	7	353	3	344	1.0e-127	450	COG0809	S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase)	348
641664333	134	49.14	18	131	13	128	2.0e-25	108	COG3654	Prophage maintenance system killer protein	132
641664334	671	53.53	3	663	28	676	0.0e+00	774	COG1200	RecG-like helicase	677
641664335	223	24.12	1	199	3	201	1.0e-09	57	COG1309	DNA-binding transcriptional regulator, AcrR family	201
641664336	325	39.6	1	300	1	293	4.0e-72	264	COG1131	ABC-type multidrug transport system, ATPase component	293
641664337	256	20	30	249	45	253	3.0e-09	55.5	COG1682	ABC-type polysaccharide/polyol phosphate export permease	263
641664338	92	46.25	4	82	1	80	3.0e-22	96.9	COG5007	Acid stress-induced BolA-like protein IbaG/YrbA, predicted regulator of iron metabolism	80
641664339	421	63.83	1	421	1	419	0.0e+00	607	COG0766	UDP-N-acetylglucosamine enolpyruvyl transferase	421
641664340	214	47.25	1	214	2	217	2.0e-57	215	COG0040	ATP phosphoribosyltransferase	290
641664341	438	50.81	6	438	1	423	0.0e+00	525	COG0141	Histidinol dehydrogenase	425
641664342	375	40.62	18	367	2	352	2.0e-76	279	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
641664343	203	57.14	8	203	2	195	5.0e-79	287	COG0131	Imidazoleglycerol phosphate dehydratase HisB	195
641664344	215	47.2	4	215	3	204	7.0e-74	270	COG0118	Imidazoleglycerol phosphate synthase glutamine amidotransferase subunit HisH	204
641664345	249	50.21	1	243	2	240	2.0e-79	288	COG0106	Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase	241
641664346	259	63.95	1	258	1	254	4.0e-110	390	COG0107	Imidazole glycerol phosphate synthase subunit HisF	256
641664349	209	41.15	2	209	1	209	9.0e-48	183	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
641664353	722	41.5	17	721	5	710	0.0e+00	602	COG0643	Chemotaxis protein histidine kinase CheA	716
641664354	594	38.03	171	521	33	408	4.0e-47	182	COG0840	Methyl-accepting chemotaxis protein	408
641664355	490	36.89	159	480	62	408	2.0e-40	160	COG0840	Methyl-accepting chemotaxis protein	408
641664356	874	37.25	38	872	6	829	0.0e+00	548	COG3127	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component	829
641664357	278	36.76	1	267	6	267	8.0e-53	200	COG3384	Aromatic ring-opening dioxygenase, catalytic subunit, LigB family	268
641664358	255	39.68	7	255	1	250	1.0e-58	219	COG0327	Putative GTP cyclohydrolase 1 type 2, NIF3 family	250
641664359	385	46.86	32	379	10	347	3.0e-66	245	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
641664360	249	44.05	1	249	3	252	8.0e-46	177	COG0805	Sec-independent protein secretion pathway component TatC	255
641664361	162	30.11	1	93	1	93	6.0e-14	70.4	COG1826	Sec-independent protein translocase protein TatA	94
641664362	82	27.16	1	80	2	82	3.0e-08	50.3	COG1826	Sec-independent protein translocase protein TatA	94
641664363	115	44.34	6	108	2	104	5.0e-27	112	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
641664364	121	49.45	19	109	1	91	2.0e-25	107	COG0140	Phosphoribosyl-ATP pyrophosphohydrolase	92
641664365	129	56.07	1	107	5	108	4.0e-42	163	COG0139	Phosphoribosyl-AMP cyclohydrolase	111
641664366	351	47.77	17	351	5	329	1.0e-88	320	COG1995	4-hydroxy-L-threonine phosphate dehydrogenase PdxA	332
641664367	288	37.76	1	285	3	288	3.0e-44	172	COG0382	4-hydroxybenzoate polyprenyltransferase	289
641664369	311	33	1	298	1	287	4.0e-37	148	COG0583	DNA-binding transcriptional regulator, LysR family	297
641664370	219	35.9	7	122	4	113	7.0e-14	70.8	COG2863	Cytochrome c553	121
641664371	410	36.63	30	357	1	344	1.0e-70	260	COG2206	HD-GYP domain, c-di-GMP phosphodiesterase class II (or its inactivated variant)	344
641664372	385	38.07	1	352	2	353	1.0e-91	330	COG1377	Flagellar biosynthesis protein FlhB	363
641664373	700	51.08	10	699	5	696	0.0e+00	799	COG1298	Flagellar biosynthesis pathway, component FlhA	696
641664374	592	29.57	206	546	64	396	2.0e-49	190	COG1419	Flagellar biosynthesis GTPase FlhF	407
641664376	238	40	1	238	16	247	2.0e-55	209	COG1191	DNA-directed RNA polymerase specialized sigma subunit	247
641664379	160	24.82	3	136	2	137	2.0e-12	65.8	COG2703	Hemerythrin	144
641664380	427	53.38	13	426	2	411	0.0e+00	510	COG0334	Glutamate dehydrogenase/leucine dehydrogenase	411
641664381	271	43.02	3	266	1	264	9.0e-60	223	COG0345	Pyrroline-5-carboxylate reductase	266
641664382	1029	35.09	71	447	30	390	2.0e-58	221	COG0506	Proline dehydrogenase	391
641664382	1029	51.32	459	1025	9	596	0.0e+00	610	COG4230	Delta 1-pyrroline-5-carboxylate dehydrogenase	769
641664383	159	48.95	10	152	6	147	6.0e-32	130	COG1522	DNA-binding transcriptional regulator, Lrp family	154
641664384	229	53.95	2	229	1	227	2.0e-75	275	COG0325	Uncharacterized pyridoxal phosphate-containing protein, affects Ilv metabolism, UPF0001 family	228
641664385	347	63.27	1	343	3	345	0.0e+00	527	COG2805	Tfp pilus assembly protein PilT, pilus retraction ATPase	353
641664386	378	64.27	4	378	1	374	0.0e+00	547	COG5008	Tfp pilus assembly protein, ATPase PilU	375
641664388	236	30.43	6	235	4	209	9.0e-31	126	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
641664390	297	50.53	13	297	2	286	2.0e-82	299	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
641664391	229	39.36	35	219	9	196	2.0e-30	126	COG2823	Osmotically-inducible protein OsmY, contains BON domain	196
641664392	197	51.96	2	180	1	176	9.0e-52	196	COG0279	Phosphoheptose isomerase	176
641664393	136	44.92	21	135	4	114	1.0e-22	99.1	COG0792	Predicted endonuclease distantly related to archaeal Holliday junction resolvase	114
641664394	354	44.37	15	297	3	275	9.0e-76	277	COG0313	16S rRNA C1402 (ribose-2'-O) methylase RsmI	275
641664395	755	46.15	571	751	1	181	9.0e-45	175	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
641664396	676	53.81	1	676	6	683	0.0e+00	800	COG0339	Zn-dependent oligopeptidase	683
641664397	287	60.99	4	284	1	281	6.0e-111	393	COG0190	5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase	283
641664398	207	54.82	9	205	6	202	6.0e-65	240	COG4566	Two-component response regulator, FixJ family, consists of REC and HTH domains	202
641664400	903	65.96	9	903	2	887	0.0e+00	1348	COG2609	Pyruvate dehydrogenase complex, dehydrogenase (E1) component	887
641664401	554	43.89	116	554	1	403	4.0e-96	345	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
641664402	607	45.15	121	592	4	454	9.0e-129	454	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
641664403	333	25.1	11	267	9	245	5.0e-14	72.2	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
641664405	306	38	53	298	64	308	6.0e-51	194	COG1477	Thiamine biosynthesis lipoprotein ApbE	337
641664406	741	35.88	15	741	1	616	7.0e-121	428	COG3211	Secreted phosphatase, PhoX family	616
641664407	263	40.85	16	247	3	225	4.0e-35	142	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
641664408	334	33.66	3	298	18	318	4.0e-54	205	COG0226	ABC-type phosphate transport system, periplasmic component	318
641664409	311	40.46	17	311	9	310	1.0e-60	227	COG0573	ABC-type phosphate transport system, permease component	310
641664410	306	39.2	6	302	1	290	1.0e-60	227	COG0581	ABC-type phosphate transport system, permease component	292
641664411	264	62.5	9	264	1	253	2.0e-117	415	COG1117	ABC-type phosphate transport system, ATPase component	253
641664412	235	36.89	4	228	7	228	2.0e-36	145	COG0704	Phosphate uptake regulator	240
641664413	245	49.34	3	227	2	228	2.0e-61	229	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
641664415	214	24.51	27	213	1	204	2.0e-10	59.2	COG0778	Nitroreductase	207
641664416	79	60.61	1	66	1	66	1.0e-21	94.4	COG1278	Cold shock protein, CspA family	67
641664417	115	50.5	13	113	5	105	9.0e-28	115	COG2127	ATP-dependent Clp protease adapter protein ClpS	107
641664418	766	46.21	1	747	1	780	0.0e+00	869	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
641664419	262	37.74	2	255	5	253	3.0e-58	218	COG3228	Mlc titration factor MtfA, regulates ptsG expression	266
641664420	282	41.44	35	250	2	218	2.0e-42	166	COG2908	UDP-2,3-diacylglucosamine pyrophosphatase LpxH	237
641664421	168	43.03	6	168	2	158	4.0e-47	180	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
641664422	189	48.78	28	189	2	158	3.0e-49	188	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
641664424	457	52.79	1	456	2	463	0.0e+00	622	COG0215	Cysteinyl-tRNA synthetase	464
641664426	322	66.67	5	319	3	317	0.0e+00	489	COG0825	Acetyl-CoA carboxylase alpha subunit	317
641664427	457	29.75	12	281	21	296	5.0e-39	155	COG0037	tRNA(Ile)-lysidine synthase TilS/MesJ	298
641664428	422	41.77	1	418	1	447	3.0e-111	395	COG0527	Aspartokinase	447
641664430	474	52.73	2	474	1	423	0.0e+00	584	COG0065	Homoaconitase/3-isopropylmalate dehydratase large subunit	423
641664431	215	53.77	1	212	1	191	6.0e-76	277	COG0066	3-isopropylmalate dehydratase small subunit	191
641664432	367	53.87	1	355	4	345	1.0e-122	433	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
641664433	375	31	4	373	4	334	2.0e-83	303	COG0136	Aspartate-semialdehyde dehydrogenase	334
641664434	883	26.8	20	883	15	755	6.0e-50	193	COG3170	Tfp pilus assembly protein FimV	755
641664435	262	44.62	1	251	2	252	1.0e-78	286	COG0101	tRNA U38,U39,U40 pseudouridine synthase TruA	266
641664436	220	44.5	7	209	1	208	1.0e-54	206	COG0135	Phosphoribosylanthranilate isomerase	208
641664437	428	68.27	5	398	1	393	0.0e+00	686	COG0133	Tryptophan synthase beta chain	396
641664438	271	42.8	1	264	1	264	5.0e-80	290	COG0159	Tryptophan synthase alpha chain	265
641664439	290	57.24	1	290	1	290	1.0e-118	419	COG0777	Acetyl-CoA carboxylase beta subunit	294
641664440	437	44.68	3	425	5	419	8.0e-116	410	COG0285	Folylpolyglutamate synthase/Dihydropteroate synthase	427
641664442	169	30.57	4	158	1	156	2.0e-13	68.7	COG1286	Uncharacterized membrane protein, required for colicin V production	182
641664443	505	50.41	1	485	4	470	0.0e+00	588	COG0034	Glutamine phosphoribosylpyrophosphate amidotransferase	470
641664444	413	42	15	411	1	393	2.0e-118	419	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
641664445	468	39.19	8	468	10	469	4.0e-125	441	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
641664451	330	51.89	10	327	6	317	5.0e-94	337	COG0837	Glucokinase	320
641664452	355	55.3	1	348	1	338	3.0e-124	438	COG3839	ABC-type sugar transport system, ATPase component	338
641664453	282	35.74	6	281	11	281	2.0e-54	206	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
641664454	295	39.45	9	295	6	293	5.0e-53	201	COG1175	ABC-type sugar transport system, permease component	295
641664455	420	24.19	1	418	4	427	2.0e-25	110	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
641664456	506	34.66	162	486	17	333	6.0e-44	172	COG0642	Signal transduction histidine kinase	336
641664457	232	43.46	1	232	1	229	7.0e-50	190	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
641664458	265	62.89	1	256	1	253	2.0e-101	361	COG0623	Enoyl-[acyl-carrier-protein] reductase (NADH)	259
641664459	183	34.84	7	156	14	151	1.0e-19	89.9	COG0779	Ribosome maturation factor RimP	153
641664460	492	51.3	159	350	1	187	6.0e-47	182	COG0195	Transcription antitermination factor NusA, contains S1 and KH domains	190
641664461	991	62.38	491	991	3	507	0.0e+00	647	COG0532	Translation initiation factor IF-2, a GTPase	509
641664462	123	38.94	10	118	6	118	4.0e-24	103	COG0858	Ribosome-binding factor A	118
641664463	339	38.01	32	322	15	271	4.0e-62	232	COG0130	tRNA U55 pseudouridine synthase TruB, may also work on U342 of tmRNA	271
641664464	606	62.87	1	606	1	601	0.0e+00	940	COG1217	Predicted membrane GTPase involved in stress response	603
641664465	305	22.26	1	299	1	293	4.0e-07	49	COG2962	Uncharacterized membrane protein RarD, contains two EamA domains	293
641664467	379	26.53	2	363	1	390	6.0e-46	178	COG1252	NADH dehydrogenase, FAD-containing subunit	405
641664469	720	31.47	1	230	1	221	1.0e-24	108	COG0398	Uncharacterized membrane protein YdjX, TVP38/TMEM64 family, SNARE-associated domain	223
641664469	720	39.52	240	695	2	454	2.0e-116	413	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
641664471	369	34.68	109	356	12	254	2.0e-45	176	COG0767	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, permease component MlaE	267
641664472	252	47.37	1	246	1	245	2.0e-68	252	COG1127	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, ATPase component MlaF	263
641664474	232	27.04	32	227	6	184	4.0e-09	55	COG3009	Uncharacterized lipoprotein YmbA	190
641664475	310	30.63	57	305	6	289	2.0e-26	113	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
641664477	468	23.04	43	424	64	418	1.0e-05	45.2	COG0439	Biotin carboxylase	449
641664478	222	24.14	1	166	3	175	3.0e-10	59.1	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
641664479	116	48.08	10	113	3	106	3.0e-19	87.4	COG2076	Multidrug transporter EmrE and related cation transporters	106
641664480	278	42.18	3	274	7	279	2.0e-50	192	COG3639	ABC-type phosphate/phosphonate transport system, permease component	283
641664481	282	39.03	14	281	24	281	4.0e-44	171	COG3639	ABC-type phosphate/phosphonate transport system, permease component	283
641664482	279	38.31	1	259	2	258	3.0e-63	235	COG3638	ABC-type phosphate/phosphonate transport system, ATPase component	258
641664483	287	39.08	31	286	37	296	2.0e-49	189	COG3221	ABC-type phosphate/phosphonate transport system, periplasmic component	299
641664484	328	39.38	13	325	14	319	2.0e-82	299	COG4301	Uncharacterized conserved protein, contains predicted SAM-dependent methyltransferase domain	321
641664485	409	24.91	209	409	71	312	3.0e-13	69.8	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
641664486	333	21.77	37	319	87	380	3.0e-16	79.7	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
641664487	355	48.55	10	353	6	346	2.0e-99	356	COG0709	Selenophosphate synthase	346
641664489	342	36.33	18	310	12	300	8.0e-73	267	COG0042	tRNA-dihydrouridine synthase	323
641664491	637	46.11	441	619	2	175	1.0e-36	148	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
641664492	307	24.68	3	307	5	290	1.0e-08	54.1	COG5006	Threonine/homoserine efflux transporter RhtA	292
641664493	279	43.12	1	268	3	265	1.0e-55	210	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
641664494	315	44.11	14	310	2	279	7.0e-64	237	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
641664495	368	50.14	11	366	4	350	2.0e-113	402	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
641664496	375	40.53	1	375	1	363	7.0e-83	301	COG0687	Spermidine/putrescine-binding periplasmic protein	363
641664497	498	48.21	23	495	5	468	0.0e+00	466	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
641664498	470	43.45	13	465	1	449	0.0e+00	512	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
641664499	454	37.64	7	451	1	441	8.0e-116	410	COG0174	Glutamine synthetase	443
641664500	256	40.64	2	247	1	241	9.0e-62	230	COG2071	Gamma-glutamyl-gamma-aminobutyrate hydrolase PuuD (putrescine degradation), contains GATase1-like domain	243
641664501	441	30.85	32	422	1	387	2.0e-51	197	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
641664502	441	45.56	11	441	10	445	0.0e+00	506	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
641664504	438	68.13	5	437	3	433	0.0e+00	630	COG2224	Isocitrate lyase	433
641664505	637	59.11	56	636	10	581	0.0e+00	772	COG0441	Threonyl-tRNA synthetase	589
641664506	135	59.26	1	135	42	176	4.0e-47	179	COG0290	Translation initiation factor IF-3	176
641664507	67	52.31	1	65	1	65	3.0e-11	59.8	COG0291	Ribosomal protein L35	65
641664508	118	72.03	1	118	1	118	6.0e-39	152	COG0292	Ribosomal protein L20	118
641664509	347	49.14	1	345	3	335	7.0e-117	413	COG0016	Phenylalanyl-tRNA synthetase alpha subunit	335
641664510	816	37.11	151	814	1	650	0.0e+00	579	COG0072	Phenylalanyl-tRNA synthetase beta subunit	650
641664511	113	46.24	13	105	1	93	8.0e-27	112	COG0776	Bacterial nucleoid DNA-binding protein	94
641664515	1014	23.02	367	997	25	615	2.0e-39	158	COG3914	Predicted O-linked N-acetylglucosamine transferase, SPINDLY family	620
641664517	647	33.83	108	634	81	616	5.0e-103	368	COG3914	Predicted O-linked N-acetylglucosamine transferase, SPINDLY family	620
641664520	779	32.23	32	752	12	708	0.0e+00	498	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
641664521	518	20.66	144	447	15	287	1.0e-09	58.8	COG1566	Multidrug resistance efflux pump	352
641664523	573	43.72	2	547	22	570	0.0e+00	504	COG4618	ABC-type protease/lipase transport system, ATPase and permease components	580
641664524	481	18.93	78	476	44	454	2.0e-17	84	COG1538	Outer membrane protein TolC	457
641664525	341	54.22	4	335	1	325	1.0e-128	452	COG0158	Fructose-1,6-bisphosphatase	326
641664526	897	36.58	1	890	4	859	0.0e+00	553	COG0308	Aminopeptidase N	859
641664527	236	34.13	14	216	2	208	3.0e-37	148	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
641664528	300	60.67	63	300	1	239	5.0e-95	341	COG1186	Protein chain release factor B	239
641664529	339	26.1	72	337	19	279	3.0e-14	72.8	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
641664532	263	37.45	26	256	1	220	3.0e-37	149	COG4340	Uncharacterized protein	226
641664533	247	27.22	4	159	12	179	7.0e-06	44.6	COG1994	Zn-dependent protease (includes SpoIVFB)	230
641664537	330	26.97	1	330	4	309	5.0e-35	141	COG2378	Predicted DNA-binding transcriptional regulator YafY, contains an HTH and WYL domains	311
641664538	1294	34.08	15	1260	4	1070	0.0e+00	695	COG1330	Exonuclease V gamma subunit	1078
641664539	1272	32.28	1	1234	5	1139	0.0e+00	617	COG1074	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)	1139
641664540	739	26.68	48	735	38	692	2.0e-83	303	COG0507	ATP-dependent exoDNAse (exonuclease V), alpha subunit, helicase superfamily I	696
641664541	392	29.05	23	374	1	357	8.0e-45	174	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
641664542	581	58.37	4	516	1	439	0.0e+00	500	COG4664	TRAP-type mannitol/chloroaromatic compound transport system, large permease component	447
641664543	197	59.54	1	173	1	173	7.0e-54	203	COG4665	TRAP-type mannitol/chloroaromatic compound transport system, small permease component	182
641664544	214	42.23	1	200	1	206	5.0e-49	187	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
641664545	501	45.63	20	476	2	457	2.0e-130	459	COG4564	Signal transduction histidine kinase	459
641664546	116	45.54	5	116	1	111	6.0e-26	109	COG3453	Predicted phosphohydrolase, protein tyrosine phosphatase (PTP) superfamily, DUF442 family	130
641664547	148	52.7	1	147	1	148	6.0e-36	143	COG1610	Uncharacterized conserved protein YqeY	148
641664548	70	62.5	1	64	1	64	2.0e-06	44.1	COG0828	Ribosomal protein S21	67
641664549	406	48.53	1	397	1	403	3.0e-121	428	COG2081	Predicted flavoprotein YhiN	408
641664550	284	18.86	3	275	1	260	2.0e-07	49.6	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
641664552	753	38.06	38	631	28	569	1.0e-117	417	COG3284	Transcriptional regulator of acetoin/glycerol metabolism	606
641664555	239	39.3	1	227	2	230	3.0e-58	218	COG1131	ABC-type multidrug transport system, ATPase component	293
641664556	338	28.86	46	336	8	302	1.0e-25	110	COG3391	DNA-binding beta-propeller fold protein YncE	381
641664557	391	18.04	58	354	27	349	5.0e-06	45.9	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
641664558	280	28.26	30	255	52	275	4.0e-11	62.2	COG0842	ABC-type multidrug transport system, permease component	286
641664563	331	33.54	4	328	1	319	5.0e-53	201	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
641664566	401	22.33	45	347	18	254	2.0e-09	57.5	COG4974	Site-specific recombinase XerD	300
641664567	222	31.18	40	222	32	207	5.0e-24	104	COG2340	Uncharacterized conserved protein YkwD, contains CAP (CSP/antigen 5/PR1) domain	207
641664568	280	49.09	2	276	1	274	6.0e-89	320	COG2961	23S rRNA A2030 N6-methylase RlmJ	279
641664569	1214	34.15	486	878	61	465	3.0e-53	204	COG2319	WD40 repeat	466
641664573	582	27.77	6	580	116	752	1.0e-103	370	COG4993	Glucose dehydrogenase	773
641664574	430	46.99	16	429	7	404	9.0e-110	390	COG0303	Molybdopterin biosynthesis enzyme	404
641664575	238	42.2	11	228	10	227	3.0e-34	138	COG4662	ABC-type tungstate transport system, periplasmic component	227
641664576	239	35.02	5	233	1	237	8.0e-48	183	COG1126	ABC-type polar amino acid transport system, ATPase component	240
641664577	282	44.84	1	280	1	273	2.0e-76	279	COG2998	ABC-type tungstate transport system, permease component	280
641664578	157	30.77	7	135	15	157	2.0e-24	105	COG0437	Fe-S-cluster-containing dehydrogenase component	203
641664579	615	43.93	1	615	2	609	0.0e+00	586	COG2414	Aldehyde:ferredoxin oxidoreductase	614
641664581	84	31.25	21	84	6	68	9.0e-06	41.7	COG2104	Sulfur carrier protein ThiS (thiamine biosynthesis)	68
641664583	97	47.42	1	97	8	104	8.0e-24	101	COG4274	Uncharacterized protein, contains GYD domain	104
641664584	386	32.65	27	120	22	117	3.0e-12	66.5	COG2005	DNA-binding transcriptional regulator ModE (molybdenum-dependent)	130
641664584	386	36.75	128	359	4	221	4.0e-38	152	COG1910	Periplasmic molybdate-binding protein/domain	223
641664586	342	21.36	81	284	30	230	3.0e-11	63	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
641664587	281	24.84	7	158	5	148	3.0e-09	55.8	COG5501	Predicted secreted protein	148
641664588	723	20.55	1	719	15	766	2.0e-38	154	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
641664590	153	34.92	19	144	1	126	7.0e-17	80	COG1846	DNA-binding transcriptional regulator, MarR family	126
641664592	250	37.36	69	248	19	195	6.0e-40	157	COG0302	GTP cyclohydrolase I	195
641664596	69	31.88	1	67	3	71	1.0e-10	57.7	COG2608	Copper chaperone CopZ	71
641664597	804	45.31	15	77	4	67	2.0e-10	61.6	COG2608	Copper chaperone CopZ	71
641664597	804	52.13	79	800	1	712	0.0e+00	717	COG2217	Cation transport ATPase	713
641664598	162	29.17	19	161	8	136	1.0e-13	69.3	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
641664599	258	35.12	13	250	3	243	1.0e-31	130	COG3503	Uncharacterized membrane protein	323
641664600	275	25	12	270	40	300	2.0e-09	56.6	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
641664601	101	49.43	9	95	3	88	1.0e-19	88.1	COG0271	Stress-induced morphogen (activity unknown)	90
641664602	212	37.86	1	206	1	177	1.0e-38	153	COG2917	Intracellular septation protein A	180
641664603	141	50.39	14	141	2	130	2.0e-52	197	COG0229	Peptide methionine sulfoxide reductase MsrB	140
641664604	503	45.84	14	503	5	488	0.0e+00	535	COG0397	Uncharacterized conserved protein YdiU, UPF0061 family	488
641664605	556	34.37	11	550	1	527	2.0e-115	410	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
641664606	178	25.21	59	176	7	119	2.0e-08	52.3	COG1403	5-methylcytosine-specific restriction endonuclease McrA	146
641664608	175	41.14	1	167	2	171	2.0e-36	145	COG3153	Predicted N-acetyltransferase YhbS	171
641664609	202	47.03	1	201	4	205	7.0e-38	150	COG2860	Uncharacterized membrane protein YeiH	209
641664610	409	46.63	1	337	16	340	1.0e-80	293	COG2951	Membrane-bound lytic murein transglycosylase B	343
641664611	478	39.32	17	426	2	346	9.0e-98	350	COG0826	Collagenase-like protease, PrtC family	347
641664612	343	32.56	1	341	3	293	5.0e-37	148	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
641664613	432	33.76	13	319	3	307	1.0e-36	147	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
641664614	253	45.16	5	248	3	250	5.0e-70	257	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
641664615	235	47.68	1	235	3	237	1.0e-71	262	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
641664616	327	24.91	1	258	10	294	4.0e-24	105	COG1305	Transglutaminase-like enzyme, putative cysteine protease	319
641664617	154	34.59	5	135	13	141	7.0e-19	86.6	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
641664618	155	43.54	8	151	5	151	5.0e-43	166	COG2153	Predicted N-acyltransferase, GNAT family	155
641664619	490	39.18	314	478	3	173	3.0e-27	116	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
641664621	398	32.74	9	332	1	326	3.0e-50	192	COG1858	Cytochrome c peroxidase	364
641664624	827	56.06	40	827	7	780	0.0e+00	921	COG2183	Transcriptional accessory protein Tex/SPT6	780
641664626	232	31	22	217	34	232	3.0e-27	115	COG3907	Membrane-associated enzyme, PAP2 (acid phosphatase) superfamily	249
641664627	575	38.55	32	569	13	554	0.0e+00	482	COG2194	Phosphoethanolamine transferase for periplasmic glucans (OPG), alkaline phosphatase superfamily	555
641664628	219	45.41	1	219	1	229	7.0e-52	197	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
641664629	428	27.06	100	420	4	328	2.0e-19	90.2	COG0642	Signal transduction histidine kinase	336
641664633	499	25.55	10	316	4	306	4.0e-09	56.6	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
641664634	321	43.57	1	314	1	311	3.0e-49	189	COG0657	Acetyl esterase/lipase	312
641664635	286	30	144	285	2	151	9.0e-17	81.1	COG2153	Predicted N-acyltransferase, GNAT family	155
641664635	286	31.88	4	141	1	137	2.0e-26	112	COG0824	Acyl-CoA thioesterase FadM	137
641664636	319	39.25	1	257	1	252	6.0e-45	174	COG3332	Uncharacterized conserved protein, contains NRDE domain	270
641664638	319	32.68	6	310	11	304	7.0e-47	181	COG0354	Folate-binding Fe-S cluster repair protein YgfZ, possible role in tRNA modification	305
641664639	328	39.04	1	327	9	341	2.0e-93	336	COG1559	Cell division protein YceG, involved in septum cleavage	342
641664640	226	47.03	26	224	3	204	2.0e-55	208	COG0125	Thymidylate kinase	208
641664642	126	43.22	9	126	1	117	6.0e-31	126	COG3215	Tfp pilus assembly protein PilZ	117
641664643	258	48.84	1	256	2	255	1.0e-77	282	COG0084	Tat protein secretion system quality control protein TatD (DNase activity)	256
641664645	178	44.1	1	161	1	156	5.0e-46	177	COG0242	Peptide deformylase	168
641664646	305	37.84	3	292	5	285	1.0e-43	170	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
641664647	143	24.83	1	143	2	139	1.0e-13	69.2	COG1585	Membrane protein implicated in regulation of membrane protease activity	140
641664648	751	41.24	144	751	4	556	0.0e+00	588	COG1982	Arginine/lysine/ornithine decarboxylase	557
641664649	758	43.36	25	753	14	697	0.0e+00	673	COG1523	Pullulanase/glycogen debranching enzyme	697
641664650	544	35.1	1	530	3	524	0.0e+00	493	COG0033	Phosphoglucomutase	524
641664651	422	54.66	12	419	2	386	0.0e+00	530	COG0448	ADP-glucose pyrophosphorylase	393
641664652	487	45.82	1	487	1	480	0.0e+00	499	COG0297	Glycogen synthase	487
641664653	842	49.2	16	819	5	750	0.0e+00	890	COG0058	Glucan phosphorylase	750
641664655	464	28.28	1	279	6	301	5.0e-28	119	COG0714	MoxR-like ATPase	329
641664656	471	24.92	154	471	10	331	1.0e-34	141	COG0642	Signal transduction histidine kinase	336
641664657	244	46.35	11	242	2	229	2.0e-62	232	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
641664658	224	30.53	1	222	13	235	1.0e-24	106	COG3471	Predicted secreted (periplasmic) protein	235
641664659	256	38.17	1	254	2	251	3.0e-43	168	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
641664660	300	26.35	18	287	10	280	8.0e-17	81.3	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
641664661	758	43.53	33	757	22	700	0.0e+00	670	COG0317	(p)ppGpp synthase/hydrolase, HD superfamily	701
641664663	195	34.62	16	189	7	188	1.0e-42	165	COG5394	Polyhydroxyalkanoate (PHA) synthesis regulator protein, binds DNA and PHA	193
641664664	214	31.86	25	206	5	207	5.0e-21	94.6	COG2755	Lysophospholipase L1 or related esterase	216
641664665	233	62.5	10	231	5	228	1.0e-75	276	COG4181	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component	228
641664666	244	44.17	6	244	23	258	6.0e-58	217	COG0566	tRNA G18 (ribose-2'-O)-methylase SpoU	260
641664667	258	45.6	9	256	1	243	4.0e-66	244	COG0846	NAD-dependent protein deacetylase, SIR2 family	250
641664668	208	54.33	1	207	2	209	3.0e-67	248	COG0035	Uracil phosphoribosyltransferase	210
641664670	344	33.64	7	331	2	311	8.0e-63	234	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
641664671	818	32.04	6	818	1	766	2.0e-117	417	COG2366	Acyl-homoserine lactone (AHL) acylase PvdQ	768
641664672	289	45.77	6	287	1	280	4.0e-78	284	COG0157	Nicotinate-nucleotide pyrophosphorylase	280
641664675	211	46.19	4	208	17	226	1.0e-65	242	COG0220	tRNA G46 methylase TrmB	227
641664676	270	50.56	2	264	6	270	5.0e-68	251	COG1968	Undecaprenyl pyrophosphate phosphatase UppP	270
641664677	416	40.78	171	415	1	239	2.0e-51	197	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
641664678	212	24.86	17	188	14	186	1.0e-06	46.6	COG1309	DNA-binding transcriptional regulator, AcrR family	201
641664679	1360	34.75	199	1036	2	732	0.0e+00	689	COG0046	Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain	743
641664679	1360	35.41	1108	1360	2	231	3.0e-63	237	COG0047	Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain	231
641664680	371	36.27	1	368	1	370	4.0e-83	301	COG0579	L-2-hydroxyglutarate oxidase LhgO	429
641664681	267	52.33	1	255	1	252	3.0e-95	341	COG0024	Methionine aminopeptidase	255
641664682	884	42.46	24	884	11	862	0.0e+00	788	COG2844	UTP:GlnB (protein PII) uridylyltransferase	867
641664683	498	36.5	8	451	7	432	2.0e-94	339	COG2265	tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family	432
641664684	315	31.34	76	315	1	267	9.0e-31	127	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
641664685	283	47.14	69	278	3	206	3.0e-54	205	COG2518	Protein-L-isoaspartate O-methyltransferase	209
641664686	253	52.63	1	241	1	246	2.0e-78	285	COG0496	Broad specificity polyphosphatase and 5'/3'-nucleotidase SurE	252
641664687	248	27.87	3	244	1	206	1.0e-24	106	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
641664688	142	30.34	3	142	7	151	1.0e-11	62.3	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
641664689	519	45.8	1	502	1	517	0.0e+00	494	COG2918	Gamma-glutamylcysteine synthetase	518
641664691	308	36.57	1	306	1	293	5.0e-70	257	COG1131	ABC-type multidrug transport system, ATPase component	293
641664693	637	25.52	124	412	28	304	2.0e-11	64.7	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
641664695	116	58.24	26	116	1	91	1.0e-25	108	COG0776	Bacterial nucleoid DNA-binding protein	94
641664696	317	24.32	22	317	6	290	3.0e-09	56.4	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
641664697	188	39.57	1	186	10	191	1.0e-21	96.6	COG0558	Phosphatidylglycerophosphate synthase	192
641664698	692	43.59	47	691	3	581	0.0e+00	582	COG0322	Excinuclease UvrABC, nuclease subunit	581
641664699	405	38.08	25	393	3	368	1.0e-74	273	COG4394	Uncharacterized protein	370
641664700	184	38.76	1	128	3	131	2.0e-32	132	COG0231	Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)	131
641664702	142	31.78	10	138	8	135	5.0e-20	90.3	COG0848	Biopolymer transport protein ExbD	137
641664703	139	38.69	1	137	1	136	6.0e-26	109	COG0848	Biopolymer transport protein ExbD	137
641664704	263	34.13	57	258	6	213	1.0e-31	130	COG0811	Biopolymer transport protein ExbB/TolQ	216
641664709	262	40	15	249	10	252	3.0e-61	228	COG1179	tRNA A37 threonylcarbamoyladenosine dehydratase	263
641664710	371	23.84	6	147	11	161	9.0e-07	48.5	COG2391	Uncharacterized membrane protein YedE/YeeE, contains two sulfur transport domains	198
641664711	283	27.78	87	283	67	262	2.0e-24	106	COG1729	Periplasmic TolA-binding protein (function unknown)	262
641664712	196	32.61	11	194	9	186	1.0e-28	119	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
641664713	427	39.37	20	425	11	424	5.0e-83	301	COG0823	Periplasmic component of the Tol biopolymer transport system	425
641664714	196	24.31	7	185	9	177	2.0e-17	82.5	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
641664715	493	45.45	1	493	1	483	0.0e+00	480	COG1530	Ribonuclease G or E	487
641664716	202	42.13	7	202	5	191	1.0e-47	183	COG0424	Predicted house-cleaning NTP pyrophosphatase, Maf/HAM1 superfamily	193
641664717	156	41.29	1	155	1	155	8.0e-45	172	COG1576	23S rRNA pseudoU1915 N3-methylase RlmH	155
641664718	250	39.45	1	109	1	109	3.0e-28	118	COG0799	Ribosomal silencing factor RsfS, regulates association of 30S and 50S subunits	115
641664719	212	39	6	205	1	195	1.0e-47	183	COG1057	Nicotinic acid mononucleotide adenylyltransferase	197
641664720	315	59.87	9	311	8	303	1.0e-119	422	COG0408	Coproporphyrinogen III oxidase	303
641664721	427	59.53	1	427	1	425	0.0e+00	603	COG0151	Phosphoribosylamine-glycine ligase	428
641664722	241	60.58	1	240	1	240	5.0e-93	334	COG0217	Transcriptional and/or translational regulatory protein YebC/TACO1	241
641664723	525	25.09	16	515	2	520	5.0e-35	142	COG0433	Archaeal DNA helicase HerA or a related bacterial ATPase, contains HAS-barrel and ATPase domains	520
641664724	162	43.08	31	160	15	137	4.0e-29	120	COG4446	Uncharacterized conserved protein, DUF1499 family	141
641664725	619	29.93	57	596	5	472	2.0e-85	310	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
641664727	152	35.17	4	147	1	132	3.0e-24	104	COG2764	Uncharacterized conserved protein PhnB, glyoxalase superfamily	136
641664729	522	22.88	4	427	3	458	4.0e-25	110	COG3593	Predicted ATP-dependent endonuclease of the OLD family, contains P-loop ATPase and TOPRIM domains	581
641664730	295	36.91	56	288	19	232	6.0e-23	101	COG2801	Transposase InsO and inactivated derivatives	232
641664731	99	28.71	1	99	1	99	6.0e-06	42.5	COG2963	Transposase and inactivated derivatives	116
641664733	122	50.42	1	119	1	116	1.0e-36	145	COG5507	Uncharacterized  conserved protein YbaA, DUF1428 family	117
641664735	424	30.83	17	375	2	366	4.0e-48	185	COG4637	Predicted ATPase	373
641664737	1025	42.09	2	1006	1	1009	0.0e+00	927	COG0841	Multidrug efflux pump subunit AcrB	1009
641664738	418	33.33	43	372	17	363	2.0e-19	90.6	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
641664739	160	60.69	18	159	4	148	8.0e-50	189	COG0328	Ribonuclease HI	154
641664741	245	29.51	2	214	31	252	2.0e-16	79.9	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
641664742	578	26.94	77	335	8	278	3.0e-06	47.5	COG0741	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)	296
641664743	198	52.06	5	198	3	196	2.0e-73	268	COG0353	Recombinational DNA repair protein RecR	198
641664744	108	52.83	1	105	2	105	1.0e-24	104	COG0718	Conserved DNA-binding protein YbaB (function unknown)	105
641664745	650	39.66	1	469	1	468	2.0e-121	430	COG2812	DNA polymerase III, gamma/tau subunits	515
641664746	372	32.69	10	361	4	345	3.0e-62	232	COG0150	Phosphoribosylaminoimidazole (AIR) synthetase	345
641664747	256	49.33	13	235	2	216	6.0e-68	250	COG2360	Leu/Phe-tRNA-protein transferase	221
641664748	247	47.5	5	243	3	242	5.0e-77	280	COG2935	Arginyl-tRNA--protein-N-Asp/Glu arginylyltransferase	253
641664750	253	34.15	2	245	6	242	8.0e-39	153	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
641664752	212	63.51	3	212	6	212	2.0e-77	281	COG2057	Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit	225
641664753	233	58.18	1	220	1	219	6.0e-81	294	COG1788	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit	220
641664756	155	52.6	1	153	3	156	1.0e-55	208	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
641664757	730	27.7	28	730	7	728	9.0e-94	338	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
641664758	332	46.79	7	328	1	324	3.0e-95	341	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
641664759	471	21.14	35	471	5	424	5.0e-48	185	COG1055	Na+/H+ antiporter NhaD or related arsenite permease	424
641664760	318	30.77	1	283	5	294	2.0e-57	216	COG0123	Acetoin utilization deacetylase AcuC or a related deacetylase	340
641664763	161	36.08	2	159	6	151	3.0e-29	121	COG2847	Copper(I)-binding protein	151
641664764	197	40.1	6	193	13	204	1.0e-36	145	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
641664765	154	44.52	5	148	9	150	6.0e-31	126	COG2847	Copper(I)-binding protein	151
641664766	233	25.65	31	209	25	209	4.0e-09	55.2	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
641664769	173	50.89	1	169	26	193	4.0e-49	187	COG3812	Uncharacterized protein	193
641664770	875	54.17	1	875	6	879	0.0e+00	1144	COG0013	Alanyl-tRNA synthetase	879
641664771	434	51.71	5	434	14	447	0.0e+00	496	COG0160	4-aminobutyrate aminotransferase or related aminotransferase	447
641664772	496	51.16	19	491	1	467	0.0e+00	529	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
641664773	304	33.93	120	286	5	171	9.0e-21	94.4	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
641664775	1155	48.74	3	1147	3	1135	0.0e+00	1318	COG1197	Transcription-repair coupling factor (superfamily II helicase)	1139
641664776	235	50.94	24	235	6	212	5.0e-54	204	COG0560	Phosphoserine phosphatase	212
641664777	288	27.73	16	267	14	266	2.0e-19	89.6	COG1639	HD-like signal output (HDOD) domain, no enzymatic activity	289
641664778	167	45.24	1	167	4	171	2.0e-38	151	COG0684	Regulator of RNase E activity RraA	210
641664779	649	39.59	21	648	2	568	3.0e-126	446	COG4232	Thiol:disulfide interchange protein	569
641664780	174	22.58	31	171	4	154	8.0e-10	56.8	COG1225	Peroxiredoxin	157
641664781	421	24.8	34	409	30	388	4.0e-15	76.4	COG2814	Predicted arabinose efflux permease, MFS family	394
641664784	372	44.34	27	352	12	324	2.0e-107	382	COG0379	Quinolinate synthase	324
641664786	541	53.18	4	537	2	516	0.0e+00	635	COG0029	Aspartate oxidase	518
641664788	865	56.14	5	853	1	775	0.0e+00	938	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
641664789	159	40.67	1	150	1	149	3.0e-44	171	COG0314	Molybdopterin synthase catalytic subunit	149
641664790	83	41.67	2	83	1	84	5.0e-15	72.7	COG1977	Molybdopterin converting factor, small subunit	84
641664791	436	47.03	20	435	6	402	3.0e-108	385	COG0303	Molybdopterin biosynthesis enzyme	404
641664792	181	47.9	1	167	2	161	1.0e-35	142	COG1763	Molybdopterin-guanine dinucleotide biosynthesis protein	161
641664793	472	32.14	1	468	1	410	8.0e-95	341	COG0498	Threonine synthase	411
641664794	438	49.85	1	326	1	333	1.0e-97	350	COG0460	Homoserine dehydrogenase	333
641664795	409	36.3	9	404	1	393	3.0e-94	339	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
641664796	123	37.1	1	122	5	127	3.0e-23	100	COG3737	Uncharacterized conserved protein, contains Mth938-like domain	127
641664797	158	46.79	1	156	2	157	6.0e-48	183	COG1225	Peroxiredoxin	157
641664798	573	49.89	109	573	1	436	0.0e+00	515	COG1875	Predicted ribonuclease YlaK, contains NYN-type RNase and PhoH-family ATPase domains	436
641664799	642	49.84	16	330	2	312	8.0e-111	394	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
641664800	492	34.43	233	476	62	285	3.0e-41	163	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
641664801	327	34.53	1	327	1	316	3.0e-48	186	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
641664802	741	20.55	212	678	116	536	3.0e-29	123	COG0747	ABC-type transport system, periplasmic component	556
641664803	308	36.61	11	296	12	298	4.0e-59	222	COG1619	Muramoyltetrapeptide carboxypeptidase LdcA (peptidoglycan recycling)	313
641664804	231	53.25	5	158	2	152	7.0e-45	173	COG0590	tRNA(Arg) A34 adenosine deaminase TadA	152
641664805	857	35.58	21	848	43	914	0.0e+00	595	COG0474	Magnesium-transporting ATPase (P-type)	917
641664806	158	44.52	1	155	1	154	3.0e-34	137	COG1522	DNA-binding transcriptional regulator, Lrp family	154
641664807	324	52.94	1	323	2	321	2.0e-86	312	COG2984	ABC-type uncharacterized transport system, periplasmic component	322
641664808	313	63.01	1	292	1	289	2.0e-84	305	COG4120	ABC-type uncharacterized transport system, permease component	293
641664809	264	61.98	1	263	1	263	4.0e-102	364	COG1101	ABC-type uncharacterized transport system, ATPase component	263
641664810	408	25.68	1	350	24	340	2.0e-30	127	COG0334	Glutamate dehydrogenase/leucine dehydrogenase	411
641664811	358	55.59	3	358	12	362	5.0e-117	414	COG3185	4-hydroxyphenylpyruvate dioxygenase and related hemolysins	363
641664812	183	25.9	5	136	2	138	1.0e-09	56.8	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
641664813	431	22.7	98	377	37	254	4.0e-25	109	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
641664814	107	41.3	9	100	5	96	2.0e-25	107	COG2154	Pterin-4a-carbinolamine dehydratase	101
641664815	303	57.09	17	284	24	291	5.0e-97	347	COG3186	Phenylalanine-4-hydroxylase	291
641664816	233	28.43	1	200	3	200	4.0e-29	121	COG0300	Short-chain dehydrogenase	265
641664817	1066	51.88	1	1065	1	1021	0.0e+00	1260	COG3696	Cu/Ag efflux pump CusA	1027
641664818	523	29.76	90	393	25	356	1.0e-14	75.2	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
641664818	523	33.33	400	495	10	108	5.0e-11	62.8	COG5569	Periplasmic Cu and Ag efflux protein CusF	108
641664819	411	22.19	29	405	50	438	3.0e-07	50.2	COG1538	Outer membrane protein TolC	457
641664822	479	34.29	97	464	48	420	6.0e-67	248	COG1322	DNA anti-recombination protein (rearrangement mutator) RmuC	448
641664823	655	29.41	6	216	5	224	1.0e-34	142	COG4121	tRNA U34 5-methylaminomethyl-2-thiouridine-forming methyltransferase MnmC	252
641664824	466	32.68	17	466	2	436	3.0e-122	432	COG0621	tRNA A37 methylthiotransferase MiaB	437
641664825	399	34.66	6	398	8	396	1.0e-84	307	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
641664826	154	57.14	1	147	6	151	1.0e-50	192	COG0691	tmRNA-binding protein	153
641664827	155	40.26	1	153	1	144	4.0e-40	157	COG2867	Ribosome association toxin PasT (RatA) of the RatAB toxin-antitoxin module	146
641664828	126	41.58	8	108	4	99	5.0e-15	73.4	COG2914	Putative antitoxin component PasI (RatB) of the RatAB toxin-antitoxin module, ubiquitin-RnfH superfamily	99
641664830	489	29.91	255	478	1	170	9.0e-33	134	COG0516	IMP dehydrogenase/GMP reductase	170
641664831	436	23.75	23	416	11	390	1.0e-13	71.4	COG2814	Predicted arabinose efflux permease, MFS family	394
641664832	532	43.96	3	202	1	198	5.0e-58	219	COG0518	GMP synthase - Glutamine amidotransferase domain	198
641664832	532	67.27	203	532	1	315	0.0e+00	535	COG0519	GMP synthase, PP-ATPase domain/subunit	315
641664833	440	31.63	2	410	5	434	3.0e-51	196	COG0038	H+/Cl- antiporter ClcA	443
641664834	147	28.03	12	140	5	133	7.0e-20	89.9	COG0824	Acyl-CoA thioesterase FadM	137
641664835	222	43.98	1	211	1	211	3.0e-47	182	COG3132	Uncharacterized conserved protein YceH, UPF0502 family	215
641664836	260	38.17	5	258	1	250	4.0e-44	171	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
641664838	561	31.89	15	474	1	396	9.0e-72	265	COG0644	Dehydrogenase (flavoprotein)	396
641664840	379	39.3	20	358	26	350	2.0e-62	233	COG3405	Endo-1,4-beta-D-glucanase Y	360
641664843	851	24.78	231	687	16	438	3.0e-51	197	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
641664844	260	38.37	17	260	14	257	5.0e-43	167	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
641664845	556	33.1	9	556	1	532	1.0e-105	377	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
641664846	390	30.85	25	387	1	341	6.0e-52	198	COG2951	Membrane-bound lytic murein transglycosylase B	343
641664847	654	44.18	1	532	3	530	0.0e+00	505	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
641664849	141	53.96	5	141	5	143	2.0e-40	158	COG1764	Organic hydroperoxide reductase OsmC/OhrA	143
641664850	309	36.94	3	305	24	332	2.0e-58	219	COG0252	L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D	351
641664851	231	39.29	6	227	3	199	2.0e-46	178	COG1974	SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase)	201
641664853	359	31.85	25	268	15	250	6.0e-29	121	COG2603	tRNA 2-selenouridine synthase SelU, contains rhodanese domain	334
641664854	245	41.43	1	242	3	250	2.0e-46	178	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
641664855	392	47.41	1	392	1	391	2.0e-91	329	COG0183	Acetyl-CoA acetyltransferase	392
641664856	586	50.66	133	584	6	445	0.0e+00	530	COG3243	Poly(3-hydroxyalkanoate) synthetase	445
641664858	273	40.7	16	270	7	249	8.0e-52	197	COG1496	Copper oxidase (laccase) domain	249
641664859	213	33.18	1	207	1	205	2.0e-31	129	COG0625	Glutathione S-transferase	211
641664860	181	32.41	35	173	1	145	2.0e-20	92	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
641664861	740	36.29	40	738	12	703	0.0e+00	573	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
641664862	468	21.11	104	445	62	341	3.0e-11	63.4	COG1566	Multidrug resistance efflux pump	352
641664864	632	23.14	406	629	6	233	4.0e-22	100	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
641664866	633	24.82	32	433	44	449	1.0e-34	141	COG1538	Outer membrane protein TolC	457
641664867	282	34.48	1	281	43	305	1.0e-46	180	COG0010	Arginase family enzyme	305
641664868	303	37.61	66	279	4	188	6.0e-40	158	COG1611	Predicted Rossmann fold nucleotide-binding protein	205
641664869	251	49	1	246	3	252	2.0e-65	242	COG0476	Molybdopterin or thiamine biosynthesis adenylyltransferase	254
641664870	482	41.44	34	428	33	400	1.0e-88	320	COG0793	C-terminal processing protease CtpA/Prc, contains a PDZ domain	406
641664871	356	38.06	1	353	4	352	5.0e-87	314	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
641664872	543	34.98	1	540	4	534	5.0e-69	255	COG1178	ABC-type Fe3+ transport system, permease component	540
641664873	506	45.49	19	501	1	472	0.0e+00	489	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
641664874	122	46.43	1	112	3	114	2.0e-28	117	COG3564	Uncharacterized conserved protein, DUF779 family	116
641664875	282	39.6	140	282	1	149	8.0e-43	167	COG0780	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF, C-terminal domain, T-fold superfamily	149
641664876	119	41.59	1	111	2	108	8.0e-28	115	COG1393	Arsenate reductase and related proteins, glutaredoxin family	117
641664877	120	39.32	4	120	3	119	4.0e-21	93.3	COG2018	Predicted regulator of Ras-like GTPase activity, Roadblock/LC7/MglB family	119
641664878	257	20.85	6	244	25	280	2.0e-12	66.5	COG3221	ABC-type phosphate/phosphonate transport system, periplasmic component	299
641664879	383	39.76	113	278	1	165	2.0e-33	136	COG4335	3-methyladenine DNA glycosylase AlkC	167
641664880	638	50.23	11	638	4	616	0.0e+00	585	COG3211	Secreted phosphatase, PhoX family	616
641664882	235	38.3	1	187	1	182	3.0e-49	188	COG0307	Riboflavin synthase alpha chain	204
641664883	183	59.66	6	181	11	186	1.0e-60	225	COG3310	Uncharacterized protein	196
641664884	306	26.25	7	302	2	291	1.0e-51	196	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
641664885	692	53.03	1	691	1	645	0.0e+00	765	COG4770	Acetyl/propionyl-CoA carboxylase, alpha subunit	645
641664886	262	37.25	8	260	8	257	2.0e-43	169	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
641664887	540	44.9	12	540	1	526	0.0e+00	639	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component	526
641664888	390	43.56	8	386	3	387	9.0e-88	317	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
641664889	234	21.39	10	208	1	201	8.0e-08	50.8	COG1309	DNA-binding transcriptional regulator, AcrR family	201
641664891	367	20.64	38	365	33	370	3.0e-08	53.2	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
641664892	1245	37.31	4	703	1	673	0.0e+00	526	COG0145	N-methylhydantoinase A/oxoprolinase/acetone carboxylase, beta subunit	674
641664892	1245	51.3	717	1237	2	520	0.0e+00	619	COG0146	N-methylhydantoinase B/oxoprolinase/acetone carboxylase, alpha subunit	563
641664893	392	23.76	82	356	3	258	8.0e-19	88.5	COG2890	Methylase of polypeptide chain release factors	280
641664895	339	34.08	1	309	18	316	9.0e-62	231	COG0042	tRNA-dihydrouridine synthase	323
641664897	203	51.32	12	200	6	181	8.0e-50	190	COG3803	Uncharacterized conserved protein, DUF924 family	182
641664904	630	34.8	36	604	13	567	2.0e-113	403	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
641664905	339	30.45	1	262	3	261	2.0e-25	110	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
641664907	366	40.95	155	364	19	222	2.0e-45	176	COG0765	ABC-type amino acid transport system, permease component	222
641664908	251	60.16	4	249	1	240	1.0e-108	386	COG1126	ABC-type polar amino acid transport system, ATPase component	240
641664910	119	39.13	3	115	5	119	1.0e-20	92.3	COG5499	Antitoxin component HigA of the HigAB toxin-antitoxin module, contains an N-terminal HTH domain	120
641664911	321	30.3	5	296	2	291	6.0e-29	121	COG0583	DNA-binding transcriptional regulator, LysR family	297
641664912	268	31.82	157	264	10	119	6.0e-18	84.7	COG0599	Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family	124
641664912	268	40.5	30	148	12	131	2.0e-15	76.4	COG1917	Cupin domain protein related to quercetin dioxygenase	131
641664914	405	36.17	62	384	4	313	8.0e-71	261	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
641664915	335	27.33	5	325	9	312	2.0e-19	90.3	COG0530	Ca2+/Na+ antiporter	320
641664917	196	34.9	1	184	3	193	2.0e-31	128	COG1014	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, gamma subunit	203
641664918	421	35.88	1	375	2	365	4.0e-78	285	COG0674	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, alpha subunit	365
641664919	343	36.27	41	338	14	293	5.0e-65	241	COG1013	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, beta subunit	294
641664920	571	35.32	36	424	30	448	1.0e-71	264	COG0493	NADPH-dependent glutamate synthase beta chain or related oxidoreductase	457
641664921	404	42.93	8	402	4	380	1.0e-80	293	COG4134	ABC-type uncharacterized transport system YnjBCD, periplasmic component	384
641664922	578	36.28	36	577	15	549	4.0e-93	335	COG4135	ABC-type uncharacterized transport system YnjBCD, permease component	551
641664923	214	55.02	5	213	3	209	5.0e-65	240	COG4136	ABC-type uncharacterized transport system YnjBCD, ATPase component	213
641664925	213	29.28	4	213	2	223	5.0e-28	117	COG1230	Co/Zn/Cd efflux system component	296
641664926	150	31.21	17	150	13	169	5.0e-11	60.4	COG1495	Disulfide bond formation protein DsbB	170
641664929	213	56.25	13	204	3	193	4.0e-65	241	COG0807	GTP cyclohydrolase II	193
641664932	368	21.68	10	362	2	325	8.0e-27	114	COG4447	Uncharacterized protein related to plant photosystem II stability/assembly factor	339
641664933	808	20.44	23	787	3	721	2.0e-78	287	COG1033	Predicted exporter protein, RND superfamily	727
641664934	123	39.62	6	108	1	106	2.0e-17	80.8	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
641664935	678	36.03	213	545	50	407	2.0e-58	220	COG0840	Methyl-accepting chemotaxis protein	408
641664938	364	34.64	36	364	6	334	2.0e-55	210	COG2855	Uncharacterized membrane protein YadS	334
641664939	546	32.54	1	540	2	527	5.0e-117	415	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
641664940	452	24.22	41	424	31	390	8.0e-19	88.7	COG2814	Predicted arabinose efflux permease, MFS family	394
641664941	330	41.92	3	330	2	326	7.0e-66	244	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
641664942	352	25.33	14	316	3	292	1.0e-28	121	COG3246	Uncharacterized conserved protein, DUF849 family	298
641664943	306	38.19	27	306	7	282	7.0e-48	184	COG2175	Taurine dioxygenase, alpha-ketoglutarate-dependent	286
641664944	888	25.93	15	883	10	891	6.0e-68	252	COG2909	ATP-, maltotriose- and DNA-dependent transcriptional regulator MalT	894
641664945	259	19.35	52	228	23	201	5.0e-08	51.7	COG2340	Uncharacterized conserved protein YkwD, contains CAP (CSP/antigen 5/PR1) domain	207
641664965	78	36.54	27	77	13	64	2.0e-06	44.5	COG3311	Predicted DNA-binding transcriptional regulator AlpA	70
641664968	415	19.25	86	399	1	309	5.0e-09	55.7	COG0582	Integrase	309
641664972	429	21.64	1	414	1	425	1.0e-27	118	COG1457	Purine-cytosine permease or related protein	442
641664973	294	52.61	17	283	1	261	7.0e-80	290	COG0351	Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase	263
641664974	220	50.25	17	212	10	207	7.0e-43	167	COG0352	Thiamine monophosphate synthase	211
641664975	295	44.53	36	290	10	261	4.0e-67	248	COG2145	Hydroxyethylthiazole kinase, sugar kinase family	265
641664976	483	22.22	9	444	7	447	9.0e-34	138	COG1070	Sugar (pentulose or hexulose) kinase	502
641664977	106	47.12	4	106	2	105	4.0e-31	126	COG3254	L-rhamnose mutarotase	105
641664978	327	37.94	10	318	13	314	9.0e-47	180	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
641664979	343	39.55	13	323	9	316	1.0e-53	204	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
641664980	535	50.69	3	505	2	499	0.0e+00	598	COG1129	ABC-type sugar transport system, ATPase component	500
641664981	330	26.92	1	309	7	317	3.0e-36	146	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
641664982	429	68.15	3	429	4	430	0.0e+00	635	COG4952	L-rhamnose isomerase	430
641664983	707	38.64	442	702	3	251	1.0e-39	158	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
641664983	707	43.94	16	435	3	404	4.0e-127	449	COG3347	Rhamnose utilisation protein RhaD, predicted bifunctional aldolase and dehydrogenase	404
641664984	314	36.13	4	310	1	296	4.0e-35	142	COG0583	DNA-binding transcriptional regulator, LysR family	297
641664985	431	29	1	418	8	438	5.0e-65	242	COG0612	Predicted Zn-dependent peptidase	438
641664986	391	61.9	108	359	19	270	4.0e-101	361	COG2326	Polyphosphate kinase 2, PPK2 family	270
641664988	123	27.48	1	123	12	142	5.0e-13	66.5	COG4190	Predicted transcriptional regulator	144
641664990	316	31.6	6	314	1	305	2.0e-31	129	COG0524	Sugar or nucleoside kinase, ribokinase family	311
641664991	332	34.16	1	322	10	321	1.0e-40	160	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
641664992	319	43.37	13	319	10	314	3.0e-55	209	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
641664994	156	45.33	1	150	1	141	1.0e-33	135	COG4154	L-fucose mutarotase/ribose pyranase, RbsD/FucU family	144
641664995	422	25.08	100	409	1	313	9.0e-36	144	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
641664996	1351	39.75	8	704	12	706	0.0e+00	543	COG1643	HrpA-like RNA helicase	845
641664997	127	29.75	2	121	2	122	2.0e-18	85	COG3324	Predicted enzyme related to lactoylglutathione lyase	127
641664998	446	34.43	24	294	1	264	5.0e-59	221	COG0548	Acetylglutamate kinase	265
641664998	446	40.43	299	439	1	141	2.0e-37	150	COG1246	N-acetylglutamate synthase or related acetyltransferase, GNAT family	153
641664999	90	58.89	1	90	1	90	8.0e-36	141	COG2924	Fe-S cluster biosynthesis and repair protein YggX	90
641665005	1113	25.12	42	660	28	614	3.0e-29	124	COG5281	Phage-related minor tail protein	833
641665011	137	44.93	1	137	1	135	3.0e-24	104	COG4387	Mu-like prophage protein gp36	139
641665013	293	36.69	1	292	2	308	7.0e-63	234	COG4397	Mu-like prophage major head subunit gpT	308
641665015	373	32	1	367	1	351	1.0e-42	167	COG4388	Mu-like prophage I protein	357
641665018	584	39.38	1	575	1	514	2.0e-123	436	COG4383	Mu-like prophage protein gp29	517
641665019	560	37.55	32	556	11	509	8.0e-115	407	COG4373	Mu-like prophage FluMu protein gp28	509
641665025	339	19.68	37	269	81	328	2.0e-12	67.1	COG3344	Retron-type reverse transcriptase	328
641665044	432	24.61	181	432	47	269	1.0e-16	81.1	COG3267	Type II secretory pathway, component ExeA (predicted ATPase)	269
641665050	99	28.71	1	99	1	99	6.0e-06	42.5	COG2963	Transposase and inactivated derivatives	116
641665051	295	36.91	56	288	19	232	4.0e-23	101	COG2801	Transposase InsO and inactivated derivatives	232
641665059	351	29.18	47	323	1	268	8.0e-37	147	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
641665060	112	26.55	1	110	13	125	8.0e-13	65.8	COG2916	DNA-binding protein H-NS	128
641665061	242	31.15	29	206	16	197	1.0e-27	116	COG0791	Cell wall-associated hydrolase, NlpC family	197
641665062	381	44.86	32	381	1	322	2.0e-96	346	COG2896	Molybdenum cofactor biosynthesis enzyme MoaA	322
641665063	165	54.49	9	164	1	156	5.0e-55	206	COG0245	2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	159
641665064	375	30.32	1	331	1	314	1.0e-37	151	COG0451	Nucleoside-diphosphate-sugar epimerase	314
641665065	233	42.17	9	232	5	230	6.0e-52	197	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	230
641665068	1650	26.34	1214	1601	69	457	2.0e-11	66.1	COG2931	Ca2+-binding protein, RTX toxin-related	510
641665069	514	27.71	62	470	21	435	6.0e-25	109	COG1538	Outer membrane protein TolC	457
641665070	739	35.2	32	726	8	695	0.0e+00	551	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
641665072	433	37.5	5	419	11	414	4.0e-74	272	COG4949	Uncharacterized membrane-anchored protein	424
641665073	536	20.46	56	402	46	382	3.0e-14	73.7	COG2814	Predicted arabinose efflux permease, MFS family	394
641665074	504	54.56	1	504	1	502	0.0e+00	569	COG3333	TctA family transporter	504
641665076	362	24.11	85	300	25	225	2.0e-06	47.3	COG2801	Transposase InsO and inactivated derivatives	232
641665079	615	40.77	122	611	23	499	0.0e+00	464	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
641665081	175	37.89	17	169	1	161	2.0e-26	112	COG3663	G:T/U-mismatch repair DNA glycosylase	169
641665082	282	38.87	5	266	3	254	6.0e-60	224	COG0084	Tat protein secretion system quality control protein TatD (DNase activity)	256
641665084	345	44.17	23	335	12	328	2.0e-62	233	COG0714	MoxR-like ATPase	329
641665086	350	22.61	54	304	33	251	7.0e-06	45.3	COG1240	Mg-chelatase subunit ChlD	261
641665088	496	43.1	266	496	1	226	1.0e-67	250	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
641665089	393	23.39	1	387	11	392	1.0e-10	61.4	COG2814	Predicted arabinose efflux permease, MFS family	394
641665091	310	42.13	85	308	4	236	3.0e-39	155	COG0412	Dienelactone hydrolase	236
641665092	440	53.3	1	424	1	413	0.0e+00	544	COG1004	UDP-glucose 6-dehydrogenase	414
641665098	127	31.09	12	124	10	128	4.0e-25	106	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
641665102	136	25.74	1	136	3	132	2.0e-14	71.4	COG2445	Uncharacterized conserved protein YutE, UPF0331/DUF86 family	138
641665110	257	37.5	1	247	2	245	8.0e-49	187	COG1922	UDP-N-acetyl-D-mannosaminuronic acid transferase, WecB/TagA/CpsF family	253
641665112	350	23.38	40	350	70	379	6.0e-16	78.5	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
641665113	352	20.87	50	326	49	366	1.0e-14	74	COG2730	Aryl-phospho-beta-D-glucosidase BglC, GH1 family	407
641665114	246	24.53	2	209	1	206	3.0e-15	75.9	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
641665116	499	22.03	13	479	7	477	1.0e-18	88.2	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
641665117	471	46.88	1	333	7	333	4.0e-112	398	COG0836	Mannose-1-phosphate guanylyltransferase	333
641665117	471	49.61	342	468	1	127	2.0e-37	150	COG0662	Mannose-6-phosphate isomerase, cupin superfamily	127
641665118	374	70.79	4	359	1	345	0.0e+00	576	COG1089	GDP-D-mannose dehydratase	345
641665119	312	33.86	6	302	2	306	8.0e-45	174	COG0451	Nucleoside-diphosphate-sugar epimerase	314
641665123	90	36.14	1	81	3	85	2.0e-08	50.5	COG3609	Transcriptional regulator, contains Arc/MetJ-type RHH (ribbon-helix-helix) DNA-binding domain	89
641665129	382	21.96	1	330	29	346	2.0e-17	84.3	COG5653	Acetyltransferase involved in cellulose biosynthesis, CelD/BcsL family	406
641665130	191	23.88	1	188	2	200	6.0e-19	87.6	COG4636	Endonuclease, Uma2 family (restriction endonuclease fold)	200
641665132	512	38.99	159	510	32	408	9.0e-42	165	COG0840	Methyl-accepting chemotaxis protein	408
641665134	306	31.66	107	304	30	227	4.0e-31	129	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
641665135	472	26.4	1	428	12	458	3.0e-44	172	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
641665136	262	29.5	23	216	45	239	3.0e-21	95.9	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
641665138	280	33.88	28	269	1	240	9.0e-40	157	COG1414	DNA-binding transcriptional regulator, IclR family	246
641665139	392	32.14	7	387	6	390	4.0e-57	215	COG0183	Acetyl-CoA acetyltransferase	392
641665140	532	39.37	1	528	5	533	8.0e-116	411	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
641665141	338	36.78	5	333	1	326	4.0e-81	294	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
641665142	622	27.71	22	187	8	173	6.0e-16	79.6	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
641665142	622	34.93	248	622	1	375	7.0e-76	278	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
641665144	265	41.53	10	248	6	250	4.0e-44	171	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
641665145	237	42.98	4	232	6	234	1.0e-55	209	COG0217	Transcriptional and/or translational regulatory protein YebC/TACO1	241
641665146	294	29.19	1	292	1	291	5.0e-21	95.4	COG0583	DNA-binding transcriptional regulator, LysR family	297
641665147	327	28.39	9	325	7	318	1.0e-44	173	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
641665148	402	50.51	8	394	6	389	3.0e-119	422	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
641665149	428	24.31	1	428	5	378	2.0e-32	133	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
641665150	99	28.71	1	99	1	99	6.0e-06	42.5	COG2963	Transposase and inactivated derivatives	116
641665151	295	36.91	56	288	19	232	4.0e-23	101	COG2801	Transposase InsO and inactivated derivatives	232
641665152	427	25.25	92	390	1	291	3.0e-09	56.9	COG0582	Integrase	309
641665155	433	40.14	2	433	6	429	9.0e-103	367	COG1253	Hemolysin or related protein, contains CBS domains	429
641665157	514	27.54	25	498	15	408	8.0e-37	148	COG4102	Uncharacterized conserved protein, DUF1501 family	418
641665158	604	28.23	14	505	15	462	2.0e-49	190	COG5267	Uncharacterized conserved protein, DUF1800 family	496
641665164	207	27.68	24	200	12	178	3.0e-16	78.8	COG2229	Signal recognition particle receptor subunit beta, a GTPase	187
641665167	232	47.09	9	230	1	220	9.0e-74	270	COG1136	ABC-type lipoprotein export system, ATPase component	226
641665168	418	43.47	1	418	1	408	3.0e-110	392	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
641665169	346	26.5	73	323	28	305	4.0e-21	95.5	COG4255	Uncharacterized protein	318
641665170	579	37.74	37	557	1	491	2.0e-92	333	COG0608	Single-stranded DNA-specific exonuclease, DHH superfamily, may be involved in archaeal DNA replication intiation	491
641665171	385	33.51	18	379	2	357	5.0e-48	185	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
641665172	205	23	1	200	2	201	2.0e-09	56.2	COG1309	DNA-binding transcriptional regulator, AcrR family	201
641665173	436	57.04	14	434	15	436	0.0e+00	520	COG1541	Phenylacetate-coenzyme A ligase PaaK, adenylate-forming domain family	438
641665174	150	30.71	5	140	1	139	3.0e-17	81.2	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
641665175	272	37.69	1	267	2	256	2.0e-46	179	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
641665176	208	46.29	1	175	2	176	3.0e-48	185	COG0663	Carbonic anhydrase or acetyltransferase, isoleucine patch superfamily	176
641665177	341	32.93	12	335	1	328	3.0e-57	215	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
641665179	373	35.45	23	368	1	312	1.0e-45	177	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
641665180	310	26.45	8	308	16	322	3.0e-30	126	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
641665181	260	39.08	4	260	1	260	1.0e-81	296	COG3622	Hydroxypyruvate isomerase	260
641665182	336	35.96	1	330	3	342	5.0e-53	202	COG0673	Predicted dehydrogenase	342
641665183	311	21.14	57	298	5	248	6.0e-17	81.9	COG1737	DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains	281
641665184	277	38.49	1	274	6	281	2.0e-66	245	COG0169	Shikimate 5-dehydrogenase	283
641665185	300	40.91	13	298	9	272	2.0e-64	239	COG3777	Hydroxyacyl-ACP dehydratase HTD2, hotdog domain	273
641665186	397	46.98	1	397	5	396	1.0e-106	380	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
641665187	271	40.07	7	270	3	276	9.0e-44	170	COG2301	Citrate lyase beta subunit	283
641665188	448	39.81	15	444	5	436	3.0e-112	399	COG0015	Adenylosuccinate lyase	438
641665191	312	32.56	5	302	1	297	1.0e-38	153	COG0583	DNA-binding transcriptional regulator, LysR family	297
641665192	698	41.12	376	695	1	317	2.0e-69	257	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
641665192	698	47.17	5	353	6	374	6.0e-103	368	COG2828	2-Methylaconitate cis-trans-isomerase PrpF (2-methyl citrate pathway)	378
641665193	357	19.84	7	357	5	354	1.0e-19	91.2	COG3203	Outer membrane protein (porin)	354
641665195	265	33.86	6	250	3	252	2.0e-42	166	COG0169	Shikimate 5-dehydrogenase	283
641665196	269	36.29	3	250	1	243	1.0e-41	163	COG1414	DNA-binding transcriptional regulator, IclR family	246
641665197	599	17.2	14	562	6	535	7.0e-30	125	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
641665200	628	65.23	128	588	2	432	0.0e+00	733	COG0422	Thiamine biosynthesis protein ThiC	432
641665201	367	30.34	1	348	1	356	8.0e-17	81.5	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
641665202	83	32.86	14	83	3	68	3.0e-08	50.2	COG2104	Sulfur carrier protein ThiS (thiamine biosynthesis)	68
641665203	277	54.2	17	276	7	262	1.0e-91	329	COG2022	Thiamin biosynthesis thiazole synthase ThiGH, ThiG subunit	262
641665204	613	28.38	365	591	15	210	1.0e-21	98.8	COG0352	Thiamine monophosphate synthase	211
641665204	613	31.89	21	321	1	256	1.0e-46	181	COG0351	Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase	263
641665206	243	30.34	29	206	1	178	6.0e-13	68.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
641665207	217	41.87	6	208	1	203	6.0e-50	190	COG2518	Protein-L-isoaspartate O-methyltransferase	209
641665208	114	33.91	1	114	3	110	4.0e-12	63.4	COG0607	Rhodanese-related sulfurtransferase	110
641665209	443	26.45	13	438	28	454	1.0e-33	137	COG1538	Outer membrane protein TolC	457
641665212	438	41.03	9	430	1	415	5.0e-102	364	COG1519	3-deoxy-D-manno-octulosonic-acid transferase	419
641665213	472	32.46	8	462	10	461	1.0e-93	337	COG1109	Phosphomannomutase	464
641665214	117	42.61	1	115	1	115	8.0e-21	92.6	COG0375	Zn finger protein HypA/HybF (possibly regulating hydrogenase expression)	115
641665215	323	37.39	57	284	2	200	2.0e-54	206	COG0378	Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase	202
641665217	87	43.24	1	72	1	74	7.0e-14	68.8	COG0298	Hydrogenase maturation factor	82
641665218	379	54.96	1	372	1	364	0.0e+00	492	COG0409	Hydrogenase maturation factor	364
641665219	351	47.51	18	351	3	339	2.0e-92	332	COG0309	Hydrogenase maturation factor	339
641665220	590	27.27	33	260	65	285	2.0e-25	111	COG0223	Methionyl-tRNA formyltransferase	307
641665221	846	34.01	187	482	53	336	4.0e-41	163	COG0642	Signal transduction histidine kinase	336
641665222	377	46.26	2	369	3	360	1.0e-90	327	COG3437	Response regulator c-di-GMP phosphodiesterase, RpfG family, contains REC and HD-GYP domains	360
641665223	267	42.75	1	261	2	255	4.0e-52	198	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
641665224	287	44.06	23	277	10	262	1.0e-68	253	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
641665225	251	34.6	3	250	1	251	1.0e-33	136	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
641665226	399	58.53	15	394	6	379	0.0e+00	461	COG3970	Fumarylacetoacetate (FAA) hydrolase family protein	379
641665227	593	41.79	1	577	3	572	0.0e+00	611	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
641665228	336	43.08	1	318	2	317	1.0e-87	317	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
641665229	310	25.85	8	300	1	288	9.0e-24	104	COG0583	DNA-binding transcriptional regulator, LysR family	297
641665230	527	27.49	8	500	3	472	4.0e-52	199	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
641665231	259	33.08	1	256	4	257	4.0e-34	138	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
641665235	236	25.22	5	230	2	225	3.0e-08	52.2	COG1842	Phage shock protein A	225
641665237	523	34.3	183	523	22	361	6.0e-64	238	COG0687	Spermidine/putrescine-binding periplasmic protein	363
641665240	719	48.9	530	711	1	180	6.0e-45	176	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
641665241	1697	33.13	42	1691	64	1619	0.0e+00	879	COG2373	Uncharacterized conserved protein YfaS, alpha-2-macroglobulin family	1621
641665242	799	43.76	9	798	8	731	0.0e+00	651	COG4953	Membrane carboxypeptidase/penicillin-binding protein PbpC	733
641665243	398	29.61	184	387	18	221	1.0e-27	118	COG5012	Methanogenic corrinoid protein MtbC1	227
641665244	446	32.26	20	446	19	438	3.0e-77	282	COG4097	Predicted ferric reductase	438
641665245	472	37.54	160	466	31	332	4.0e-44	172	COG0642	Signal transduction histidine kinase	336
641665246	241	46.46	8	229	2	226	6.0e-58	217	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
641665247	325	28.31	14	322	1	311	7.0e-34	138	COG0524	Sugar or nucleoside kinase, ribokinase family	311
641665249	438	31.55	17	438	6	397	1.0e-71	263	COG2133	Glucose/arabinose dehydrogenase, beta-propeller fold	399
641665250	846	32.45	405	705	46	336	1.0e-39	159	COG0642	Signal transduction histidine kinase	336
641665254	533	42.31	118	533	5	381	4.0e-120	425	COG2721	Altronate dehydratase	381
641665255	320	40.63	1	313	1	313	7.0e-64	237	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
641665256	467	34.54	1	467	1	427	1.0e-85	310	COG1236	RNA processing exonuclease, beta-lactamase fold, Cft2 family	427
641665257	328	35.26	1	299	12	322	1.0e-59	223	COG1161	Ribosome biogenesis GTPase A	322
641665259	206	56.25	13	204	3	193	2.0e-64	239	COG0807	GTP cyclohydrolase II	193
641665260	220	53.99	1	213	2	214	3.0e-65	241	COG1788	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit	220
641665261	219	55.56	1	214	5	220	1.0e-68	252	COG2057	Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit	225
641665266	305	30.52	5	300	6	301	8.0e-44	171	COG0462	Phosphoribosylpyrophosphate synthetase	314
641665267	509	32.38	93	496	1	415	1.0e-90	327	COG0213	Thymidine phosphorylase	435
641665269	562	39.55	5	270	9	269	4.0e-49	189	COG3267	Type II secretory pathway, component ExeA (predicted ATPase)	269
641665270	102	54.55	1	99	1	99	4.0e-26	109	COG3162	Uncharacterized membrane protein, DUF485 family	102
641665271	607	50.96	35	599	1	529	0.0e+00	470	COG4147	Na+(or H+)/acetate symporter ActP	529
641665272	957	37.87	240	509	66	326	4.0e-40	160	COG0642	Signal transduction histidine kinase	336
641665273	218	25.67	38	217	12	182	2.0e-16	79.5	COG0847	DNA polymerase III, epsilon subunit or related 3'-5' exonuclease	243
641665274	612	31.39	1	609	4	609	1.0e-110	394	COG2905	Signal-transduction protein containing cAMP-binding, CBS, and nucleotidyltransferase domains	610
641665275	768	51.18	29	747	2	667	0.0e+00	866	COG0272	NAD-dependent DNA ligase	667
641665277	347	31.03	3	336	5	349	5.0e-71	261	COG0820	Adenine C2-methylase RlmN of 23S rRNA A2503 and tRNA A37	349
641665280	788	24.21	176	768	8	632	3.0e-60	226	COG1199	Rad3-related DNA helicase	654
641665281	249	29.72	1	184	13	223	8.0e-20	90.7	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
641665282	167	46	1	150	7	156	2.0e-46	178	COG1607	Acyl-CoA hydrolase	157
641665284	1170	32.01	1	1168	1	1163	0.0e+00	560	COG1196	Chromosome segregation ATPase	1163
641665285	407	30.98	4	404	3	393	9.0e-76	277	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
641665286	274	48.75	2	274	1	270	7.0e-79	287	COG2171	Tetrahydrodipicolinate N-succinyltransferase	271
641665287	404	45.3	2	362	4	363	5.0e-101	361	COG5008	Tfp pilus assembly protein, ATPase PilU	375
641665288	382	38.58	6	382	16	408	3.0e-79	288	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
641665289	319	31.62	29	299	1	257	3.0e-44	172	COG2890	Methylase of polypeptide chain release factors	280
641665291	370	66.86	23	368	4	350	0.0e+00	544	COG0722	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase	351
641665292	74	39.73	2	74	1	73	2.0e-14	70.6	COG2501	Ribosome-associated protein YbcJ, S4-like RNA binding protein	73
641665293	333	23.23	52	333	2	281	1.0e-15	77.7	COG4395	Predicted lipid-binding transport protein, Tim44 family	281
641665296	272	30.11	4	263	24	292	6.0e-33	134	COG0668	Small-conductance mechanosensitive channel	316
641665297	502	35.89	1	486	29	513	2.0e-112	399	COG0513	Superfamily II DNA and RNA helicase	513
641665298	475	30.6	169	475	32	333	3.0e-30	126	COG0642	Signal transduction histidine kinase	336
641665299	232	45.02	2	226	1	226	2.0e-51	195	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
641665301	205	26.04	14	202	1	189	1.0e-09	56.6	COG0558	Phosphatidylglycerophosphate synthase	192
641665303	309	38.28	18	303	3	278	9.0e-63	234	COG3220	Uncharacterized conserved protein, UPF0276 family	282
641665304	95	48.19	1	82	11	92	2.0e-10	57.5	COG5572	Uncharacterized membrane protein	104
641665305	189	28.49	1	179	14	180	9.0e-21	93.6	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641665307	318	30.61	1	315	4	332	4.0e-60	225	COG2070	NAD(P)H-dependent flavin oxidoreductase YrpB, nitropropane dioxygenase family	336
641665308	596	33.95	35	460	7	393	7.0e-66	245	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
641665309	308	53.65	1	308	1	310	1.0e-80	293	COG2025	Electron transfer flavoprotein, alpha subunit	313
641665310	249	48.85	1	249	1	260	9.0e-70	256	COG2086	Electron transfer flavoprotein, alpha and beta subunits	260
641665311	272	43.53	11	265	7	258	4.0e-68	251	COG0796	Glutamate racemase	269
641665316	805	66.92	10	782	6	782	0.0e+00	1166	COG0466	ATP-dependent Lon protease, bacterial type	782
641665317	424	70.49	16	424	1	405	0.0e+00	685	COG1219	ATP-dependent protease Clp, ATPase subunit	408
641665318	202	73.82	11	201	3	193	8.0e-86	309	COG0740	ATP-dependent protease ClpP, protease subunit	200
641665319	435	41.5	1	434	1	438	2.0e-95	342	COG0544	FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)	441
641665321	1047	27.82	15	1037	1	1008	0.0e+00	817	COG0841	Multidrug efflux pump subunit AcrB	1009
641665322	393	24.46	1	362	3	365	6.0e-14	72.5	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
641665323	276	28.04	4	273	19	282	5.0e-32	131	COG1562	Phytoene/squalene synthetase	288
641665324	278	43.42	1	278	7	287	9.0e-62	230	COG1562	Phytoene/squalene synthetase	288
641665325	432	23.41	1	427	1	436	1.0e-23	104	COG2907	Predicted NAD/FAD-binding protein	447
641665326	193	52.26	1	193	2	199	1.0e-66	245	COG0605	Superoxide dismutase	204
641665327	432	45.87	12	427	5	438	9.0e-112	397	COG1570	Exonuclease VII, large subunit	440
641665328	192	35.26	1	189	26	211	6.0e-29	120	COG0811	Biopolymer transport protein ExbB/TolQ	216
641665329	141	31.91	1	138	1	137	2.0e-22	98	COG0848	Biopolymer transport protein ExbD	137
641665330	348	39.94	8	346	1	336	5.0e-69	254	COG1663	Tetraacyldisaccharide-1-P 4'-kinase	336
641665331	67	50.91	1	55	1	55	4.0e-15	72.9	COG2835	Uncharacterized conserved protein YbaR, Trm112 family	60
641665332	271	57.03	22	270	2	242	2.0e-87	315	COG1212	CMP-2-keto-3-deoxyoctulosonic acid synthetase	247
641665333	217	42.99	1	217	1	178	9.0e-49	187	COG0563	Adenylate kinase or related kinase	178
641665334	252	37.5	1	248	1	251	1.0e-29	123	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
641665335	599	43.01	48	599	14	539	0.0e+00	485	COG0405	Gamma-glutamyltranspeptidase	539
641665336	598	44.62	1	444	1	431	1.0e-117	417	COG0358	DNA primase (bacterial type)	568
641665337	754	45.13	396	752	1	342	1.0e-93	338	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
641665338	310	30.46	1	171	41	213	9.0e-21	94.5	COG2114	Adenylate cyclase, class 3	227
641665339	231	26.69	1	231	2	228	8.0e-25	107	COG1011	FMN phosphatase YigB, HAD superfamily	229
641665340	368	44.14	18	340	4	320	9.0e-102	363	COG0276	Protoheme ferro-lyase (ferrochelatase)	320
641665341	307	23.08	9	289	7	326	4.0e-20	92.3	COG3203	Outer membrane protein (porin)	354
641665342	495	52.23	1	493	1	493	0.0e+00	531	COG3333	TctA family transporter	504
641665344	319	37.46	11	319	8	318	1.0e-62	233	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
641665345	222	40	1	222	1	229	6.0e-47	180	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
641665346	489	30.75	156	486	21	335	7.0e-35	142	COG0642	Signal transduction histidine kinase	336
641665347	153	54.02	21	107	9	93	9.0e-20	89.6	COG1188	Ribosomal 50S subunit-recycling heat shock protein, contains S4 domain	100
641665350	181	42.78	3	181	15	193	2.0e-35	142	COG0576	Molecular chaperone GrpE (heat shock protein)	193
641665351	646	59.14	1	606	4	579	0.0e+00	667	COG0443	Molecular chaperone DnaK (HSP70)	579
641665352	385	56.59	1	385	1	370	0.0e+00	469	COG0484	DnaJ-class molecular chaperone with C-terminal Zn finger domain	371
641665354	425	50.77	28	416	6	381	1.0e-115	410	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
641665355	334	23.39	44	285	5	248	7.0e-18	85.1	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
641665357	298	43.58	13	268	1	253	5.0e-51	194	COG0613	Predicted metal-dependent phosphoesterase TrpH, contains PHP domain	258
641665359	208	38.92	2	203	1	202	6.0e-51	193	COG0009	tRNA A37 threonylcarbamoyladenosine synthetase subunit TsaC/SUA5/YrdC	211
641665360	166	41.18	11	162	2	154	4.0e-34	137	COG2606	Cys-tRNA(Pro) deacylase, prolyl-tRNA editing enzyme YbaK/EbsC	155
641665361	263	45.05	13	211	1	200	1.0e-48	186	COG0344	Phospholipid biosynthesis protein PlsY, probable glycerol-3-phosphate acyltransferase	200
641665363	352	38.42	1	351	1	315	1.0e-69	256	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
641665364	375	47.41	1	359	10	360	2.0e-94	339	COG3437	Response regulator c-di-GMP phosphodiesterase, RpfG family, contains REC and HD-GYP domains	360
641665365	1959	38.01	1190	1459	77	333	5.0e-41	164	COG0642	Signal transduction histidine kinase	336
641665368	398	34.63	35	390	1	356	7.0e-55	208	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
641665370	145	32.19	3	143	1	141	1.0e-18	85.7	COG2927	DNA polymerase III, chi subunit	144
641665371	486	48.97	9	486	5	485	0.0e+00	483	COG0260	Leucyl aminopeptidase	485
641665372	364	27.4	1	354	2	364	2.0e-35	143	COG0795	Lipopolysaccharide export LptBFGC system, permease protein LptF	364
641665373	368	28.76	1	366	1	363	2.0e-43	170	COG0795	Lipopolysaccharide export LptBFGC system, permease protein LptF	364
641665375	321	29.61	1	303	1	295	2.0e-31	130	COG0583	DNA-binding transcriptional regulator, LysR family	297
641665376	396	37.5	27	394	21	389	7.0e-86	311	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
641665378	231	36.41	1	211	1	211	2.0e-41	162	COG0625	Glutathione S-transferase	211
641665379	417	35.06	130	356	64	294	4.0e-30	126	COG1305	Transglutaminase-like enzyme, putative cysteine protease	319
641665380	935	29.6	608	926	3	310	9.0e-28	119	COG2307	Uncharacterized conserved protein, Alpha-E superfamily	313
641665380	935	42.15	109	591	24	488	3.0e-125	443	COG2308	Uncharacterized conserved protein, circularly permuted ATPgrasp superfamily	488
641665382	319	40.81	1	316	1	309	3.0e-74	272	COG2307	Uncharacterized conserved protein, Alpha-E superfamily	313
641665383	477	59.7	5	477	12	478	0.0e+00	665	COG2308	Uncharacterized conserved protein, circularly permuted ATPgrasp superfamily	488
641665384	833	33.01	506	811	15	293	2.0e-49	191	COG2333	Metal-dependent hydrolase, beta-lactamase superfamily II	293
641665385	152	28.77	6	151	1	128	1.0e-13	69.2	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
641665386	165	23.08	1	165	7	168	3.0e-07	48.1	COG1495	Disulfide bond formation protein DsbB	170
641665388	153	39.86	22	153	7	149	1.0e-18	85.5	COG2165	Type II secretory pathway, pseudopilin PulG	149
641665389	382	35.38	43	381	59	396	1.0e-55	210	COG1459	Type II secretory pathway, component PulF	397
641665390	580	43.61	72	576	6	498	0.0e+00	487	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
641665395	662	29.65	18	618	8	571	5.0e-63	236	COG4796	Type II secretory pathway, component HofQ	709
641665396	159	27.95	1	159	1	149	3.0e-12	65.1	COG2165	Type II secretory pathway, pseudopilin PulG	149
641665397	184	30.89	17	137	3	121	1.0e-09	56.2	COG2165	Type II secretory pathway, pseudopilin PulG	149
641665399	519	29.57	157	483	19	335	7.0e-36	145	COG0642	Signal transduction histidine kinase	336
641665400	239	43.04	1	220	1	229	8.0e-56	210	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
641665403	425	24.76	26	225	5	207	2.0e-24	107	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
641665404	551	20.42	171	536	4	356	1.0e-11	65.1	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
641665408	774	40.69	21	760	11	731	0.0e+00	687	COG0188	DNA gyrase/topoisomerase IV, subunit A	804
641665411	658	44.51	7	654	3	630	0.0e+00	726	COG0187	DNA gyrase/topoisomerase IV, subunit B	635
641665413	414	21.63	40	393	36	381	1.0e-15	77.9	COG2814	Predicted arabinose efflux permease, MFS family	394
641665416	293	52.7	1	293	2	297	6.0e-89	320	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
641665417	398	28.35	21	398	9	342	1.0e-41	164	COG3317	Uncharacterized lipoprotein	342
641665418	418	32.49	39	416	6	382	3.0e-63	235	COG2850	Ribosomal protein L16 Arg81 hydroxylase, contains JmjC domain	383
641665419	177	35.48	1	150	1	148	9.0e-23	99	COG1047	FKBP-type peptidyl-prolyl cis-trans isomerase 2	174
641665420	150	50	16	149	16	147	2.0e-45	174	COG0756	dUTPase	148
641665421	419	48.77	8	410	2	391	2.0e-102	365	COG0452	Phosphopantothenoylcysteine synthetase/decarboxylase	392
641665422	790	19.13	86	767	39	683	2.0e-35	145	COG4771	Outer membrane receptor for ferrienterochelin and colicins	699
641665423	404	34.61	6	399	2	404	6.0e-78	285	COG0004	Ammonia channel protein AmtB	409
641665424	479	40.33	1	479	29	507	9.0e-117	414	COG0513	Superfamily II DNA and RNA helicase	513
641665428	257	51.57	1	253	1	250	8.0e-82	296	COG3022	Cytoplasmic iron level regulating protein YaaA, DUF328/UPF0246 family	253
641665429	142	48.03	10	131	2	126	3.0e-36	143	COG3012	Uncharacterized conserved protein YchJ, contains N- and C-terminal SEC-C domains	151
641665431	212	54.98	1	211	1	211	5.0e-79	287	COG0177	Endonuclease III	211
641665432	269	26.79	8	261	52	312	3.0e-29	122	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
641665433	131	53.6	2	126	1	125	7.0e-47	179	COG0853	Aspartate 1-decarboxylase	126
641665434	216	31.38	7	184	5	180	1.0e-11	63.7	COG0406	Broad specificity phosphatase PhoE	208
641665435	264	38.43	9	263	3	245	4.0e-32	131	COG0368	Cobalamin synthase	246
641665436	359	39.7	12	341	14	334	8.0e-62	230	COG2038	NaMN:DMB phosphoribosyltransferase	347
641665437	513	42.07	9	508	1	486	2.0e-129	456	COG1492	Cobyric acid synthase	486
641665438	265	43.57	21	258	8	248	1.0e-62	233	COG1120	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	258
641665439	335	38.64	6	333	1	330	4.0e-44	171	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
641665440	303	28.72	22	286	30	309	5.0e-30	124	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
641665441	191	48.31	10	186	4	174	7.0e-42	163	COG2087	Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase	175
641665442	638	22.83	20	638	10	608	5.0e-37	149	COG4206	Outer membrane cobalamin receptor protein	608
641665446	157	57.05	3	157	1	153	1.0e-51	195	COG2947	Predicted RNA-binding protein, contains PUA-like domain	156
641665447	270	30.51	3	268	2	254	2.0e-09	56.9	COG0730	Uncharacterized membrane protein YfcA	258
641665448	328	33.52	138	318	3	181	1.0e-17	84	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
641665450	454	22.51	32	453	3	387	2.0e-32	133	COG0247	Fe-S oxidoreductase	388
641665451	139	45.52	4	137	1	129	5.0e-33	133	COG1592	Rubrerythrin	166
641665452	383	32	2	151	43	192	1.0e-21	98	COG3707	Two-component response regulator, AmiR/NasT family, consists of REC and RNA-binding antiterminator (ANTAR) domains	194
641665453	418	35.41	6	391	6	406	6.0e-63	235	COG2223	Nitrate/nitrite transporter NarK	417
641665454	580	26.62	269	539	1	284	2.0e-28	121	COG0515	Serine/threonine protein kinase	384
641665454	580	28.35	1	239	4	253	3.0e-30	127	COG0631	Serine/threonine protein phosphatase PrpC	262
641665455	821	58.38	1	800	1	777	0.0e+00	1091	COG1251	NAD(P)H-nitrite reductase, large subunit	793
641665456	118	39.62	1	104	2	106	4.0e-21	93.5	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
641665457	933	34.11	1	722	38	765	0.0e+00	476	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
641665458	444	47.06	1	442	1	456	0.0e+00	490	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
641665459	635	39.35	10	627	1	603	1.0e-122	434	COG4191	Signal transduction histidine kinase regulating C4-dicarboxylate transport system	603
641665461	1614	50.12	1	1609	1	1586	0.0e+00	1668	COG2902	NAD-specific glutamate dehydrogenase	1592
641665462	244	61.16	1	242	2	240	9.0e-107	379	COG1126	ABC-type polar amino acid transport system, ATPase component	240
641665463	221	41.26	1	221	1	222	4.0e-47	181	COG0765	ABC-type amino acid transport system, permease component	222
641665464	247	34.43	30	241	13	222	1.0e-44	173	COG0765	ABC-type amino acid transport system, permease component	222
641665465	300	28.67	1	272	2	272	1.0e-30	127	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
641665466	356	39.22	26	355	17	347	8.0e-79	287	COG0252	L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D	351
641665467	309	28.52	1	298	2	299	2.0e-40	159	COG0547	Anthranilate phosphoribosyltransferase	338
641665468	632	38.81	45	615	1	528	0.0e+00	549	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
641665470	691	50.94	1	691	1	644	0.0e+00	791	COG4770	Acetyl/propionyl-CoA carboxylase, alpha subunit	645
641665471	510	58.4	8	510	18	526	0.0e+00	702	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component	526
641665472	351	47.2	25	346	13	319	6.0e-88	318	COG1703	Putative periplasmic protein kinase ArgK or related GTPase of G3E family	323
641665474	720	55.3	585	716	10	141	7.0e-41	162	COG2185	Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding)	143
641665474	720	60.83	4	553	2	548	0.0e+00	707	COG1884	Methylmalonyl-CoA mutase, N-terminal domain/subunit	548
641665475	232	33.95	20	232	6	220	2.0e-31	129	COG1802	DNA-binding transcriptional regulator, GntR family	230
641665476	386	56.7	1	386	1	385	0.0e+00	517	COG0045	Succinyl-CoA synthetase, beta subunit	387
641665477	297	56.04	1	297	1	289	3.0e-101	361	COG0074	Succinyl-CoA synthetase, alpha subunit	293
641665478	437	50.37	31	437	1	390	0.0e+00	475	COG0372	Citrate synthase	390
641665479	91	33.33	1	90	6	94	2.0e-11	60.3	COG2938	Succinate dehydrogenase flavin-adding protein, antitoxin component of the CptAB toxin-antitoxin module	94
641665480	234	58.55	3	234	2	232	1.0e-83	302	COG0479	Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit	234
641665481	602	47.29	7	588	2	562	0.0e+00	585	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
641665482	120	37.39	6	120	2	116	2.0e-18	84.5	COG2142	Succinate dehydrogenase, hydrophobic anchor subunit	117
641665483	142	30.77	18	142	8	130	4.0e-09	53.8	COG2009	Succinate dehydrogenase/fumarate reductase, cytochrome b subunit	132
641665484	259	38.91	20	258	1	236	3.0e-45	175	COG2188	DNA-binding transcriptional regulator, GntR family	236
641665485	328	29.14	6	328	1	311	1.0e-63	237	COG0039	Malate/lactate dehydrogenase	313
641665486	350	22.5	59	334	21	280	2.0e-22	100	COG2301	Citrate lyase beta subunit	283
641665488	863	76.65	1	862	1	851	0.0e+00	1457	COG1049	Aconitase B	852
641665489	303	25	22	299	85	416	6.0e-23	101	COG1793	ATP-dependent DNA ligase	444
641665490	484	50	3	480	8	475	0.0e+00	588	COG2925	Exonuclease I	475
641665492	464	41.81	234	464	1	226	2.0e-64	240	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
641665495	1255	36.14	538	821	58	326	4.0e-43	171	COG0642	Signal transduction histidine kinase	336
641665499	978	24.65	760	966	6	216	2.0e-17	85.3	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
641665500	399	23.71	15	363	9	367	3.0e-26	113	COG3434	c-di-GMP-related signal transduction protein, contains EAL and HDOD domains	407
641665501	405	21.34	1	403	1	357	2.0e-31	130	COG1344	Flagellin and related hook-associated protein FlgL	360
641665502	640	27.45	1	451	1	452	3.0e-58	220	COG1256	Flagellar hook-associated protein FlgK	552
641665503	348	45.51	159	325	22	181	5.0e-39	155	COG1705	Flagellum-specific peptidoglycan hydrolase FlgJ	201
641665504	392	58.63	28	392	3	365	4.0e-123	434	COG1706	Flagellar basal body P-ring protein FlgI	365
641665505	233	38.7	9	230	1	230	4.0e-40	158	COG2063	Flagellar basal body L-ring protein FlgH	230
641665506	260	56.82	1	260	1	263	2.0e-82	299	COG4786	Flagellar basal body rod protein FlgG	265
641665507	241	48.81	1	241	1	251	5.0e-66	244	COG4787	Flagellar basal body rod protein FlgF	251
641665509	224	32.88	4	219	2	218	7.0e-30	123	COG1843	Flagellar hook assembly protein FlgD	222
641665510	136	57.66	1	134	1	137	5.0e-40	156	COG1558	Flagellar basal body rod protein FlgC	137
641665511	134	38.89	8	133	7	132	6.0e-25	106	COG1815	Flagellar basal body rod protein FlgB	133
641665512	255	27.66	69	255	37	220	2.0e-21	96.2	COG1261	Flagella basal body P-ring formation protein FlgA	220
641665513	106	29.89	12	98	6	92	6.0e-07	45.7	COG2747	Negative regulator of flagellin synthesis (anti-sigma28 factor)	93
641665517	189	42.19	3	189	2	181	1.0e-60	225	COG0717	Deoxycytidine triphosphate deaminase	183
641665518	179	35.5	6	170	2	169	4.0e-25	107	COG4539	Uncharacterized membrane protein YGL010W	180
641665519	123	21.05	10	123	21	127	4.0e-07	46.9	COG2916	DNA-binding protein H-NS	128
641665520	347	38.4	4	344	1	325	2.0e-66	246	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
641665521	446	33.33	101	445	2	336	2.0e-42	167	COG0642	Signal transduction histidine kinase	336
641665522	489	34.13	195	462	116	408	2.0e-37	150	COG0840	Methyl-accepting chemotaxis protein	408
641665524	292	43.77	10	289	1	264	4.0e-67	248	COG1526	Formate dehydrogenase assembly factor FdhD	266
641665527	969	44.65	20	947	2	957	0.0e+00	1183	COG3383	Predicted molibdopterin-dependent oxidoreductase YjgC	978
641665528	523	51.67	95	513	1	416	0.0e+00	541	COG1894	NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F)	424
641665529	173	37.25	8	160	7	158	4.0e-37	147	COG1905	NADH:ubiquinone oxidoreductase 24 kD subunit (chain E)	160
641665530	320	29.05	4	297	3	282	1.0e-20	94.3	COG0583	DNA-binding transcriptional regulator, LysR family	297
641665532	364	43.46	59	314	19	265	1.0e-58	220	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
641665533	111	21.98	12	95	7	95	4.0e-08	50.1	COG0633	Ferredoxin	102
641665534	351	24.66	64	273	8	209	5.0e-14	72.3	COG0412	Dienelactone hydrolase	236
641665535	689	38.26	578	688	10	123	2.0e-22	101	COG0073	tRNA-binding EMAP/Myf domain	123
641665535	689	38.49	1	561	3	554	0.0e+00	580	COG0143	Methionyl-tRNA synthetase	558
641665536	261	29.58	22	260	12	223	3.0e-11	62.6	COG3619	Uncharacterized membrane protein YoaK, UPF0700 family	226
641665537	607	38.64	29	595	9	546	1.0e-102	367	COG0659	Sulfate permease or related transporter, MFS superfamily	554
641665539	303	43.51	55	287	1	239	2.0e-47	183	COG1354	Chromatin segregation and condensation protein Rec8/ScpA/Scc1, kleisin family	248
641665541	325	24.27	125	322	1	167	6.0e-17	81.8	COG0516	IMP dehydrogenase/GMP reductase	170
641665543	352	26.22	7	330	8	305	4.0e-26	112	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
641665544	848	40.45	52	736	3	652	0.0e+00	577	COG0210	Superfamily I DNA or RNA helicase	655
641665545	165	47.44	9	164	2	156	7.0e-46	176	COG0783	DNA-binding ferritin-like protein (oxidative damage protectant)	156
641665546	417	64.39	10	417	2	406	0.0e+00	599	COG0538	Isocitrate dehydrogenase	407
641665547	239	28.19	1	183	1	183	4.0e-07	48.7	COG2836	Sulfite exporter TauE/SafE	232
641665548	487	38.94	43	475	7	414	4.0e-116	412	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
641665549	245	32.35	30	232	9	212	3.0e-35	142	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
641665552	495	33.9	45	449	1	383	1.0e-74	274	COG0348	Polyferredoxin	386
641665553	310	30.16	87	208	5	126	1.0e-10	61.1	COG2010	Cytochrome c, mono- and diheme variants	150
641665555	209	57.87	11	205	3	218	2.0e-84	304	COG2993	Cbb3-type cytochrome oxidase, cytochrome c subunit	227
641665556	479	72.18	5	479	4	481	0.0e+00	685	COG3278	Cbb3-type cytochrome oxidase, subunit 1	482
641665557	56	47.73	1	44	1	44	5.0e-10	56	COG3197	Uncharacterized protein, possibly involved in nitrogen fixation	58
641665558	805	37.87	51	784	3	709	0.0e+00	555	COG2217	Cation transport ATPase	713
641665559	177	44.26	54	175	2	123	8.0e-32	130	COG1430	Uncharacterized conserved membrane protein, UPF0127 family	126
641665560	263	28.24	9	262	8	253	2.0e-09	56.2	COG0730	Uncharacterized membrane protein YfcA	258
641665561	568	36.85	1	551	1	509	2.0e-123	436	COG0155	Sulfite reductase, beta subunit (hemoprotein)	510
641665562	178	33.97	9	162	16	167	1.0e-24	106	COG3749	Uncharacterized conserved protein, DUF934 family	167
641665563	244	38.94	19	239	25	246	5.0e-47	181	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
641665564	323	29.97	5	323	5	261	5.0e-42	165	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
641665565	440	46.21	23	438	7	414	9.0e-122	430	COG2895	Sulfate adenylyltransferase subunit 1, EFTu-like GTPase family	431
641665566	240	43.04	1	225	3	231	3.0e-52	198	COG0007	Uroporphyrinogen-III methylase (siroheme synthase)	244
641665567	107	37.88	4	65	5	68	4.0e-08	49.8	COG1146	NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit	68
641665568	368	27.5	28	343	5	304	3.0e-37	149	COG0492	Thioredoxin reductase	305
641665569	744	32.14	446	724	65	328	3.0e-35	143	COG0642	Signal transduction histidine kinase	336
641665573	259	51.2	10	258	4	253	4.0e-81	294	COG0623	Enoyl-[acyl-carrier-protein] reductase (NADH)	259
641665575	469	29.93	191	461	23	323	1.0e-43	171	COG0280	Phosphotransacetylase	327
641665575	469	32.41	12	149	14	158	1.0e-16	81.3	COG2030	Acyl dehydratase	159
641665576	416	43.07	22	414	3	395	3.0e-113	401	COG0282	Acetate kinase	396
641665578	194	34.84	36	179	46	192	1.0e-17	83	COG1525	Endonuclease YncB, thermonuclease family	192
641665579	473	56.37	1	463	1	452	0.0e+00	673	COG4303	Ethanolamine ammonia-lyase, large subunit	453
641665580	286	45.12	4	249	61	294	3.0e-59	222	COG4302	Ethanolamine ammonia-lyase, small subunit	294
641665582	598	18.28	43	289	2	277	2.0e-10	61.7	COG0515	Serine/threonine protein kinase	384
641665582	598	20.61	292	514	1	210	5.0e-08	53	COG1639	HD-like signal output (HDOD) domain, no enzymatic activity	289
641665584	420	68.74	1	419	4	421	0.0e+00	683	COG1158	Transcription termination factor Rho	422
641665585	85	41.86	1	85	1	73	2.0e-14	70.7	COG0254	Ribosomal protein L31	75
641665586	537	19.02	1	456	5	451	5.0e-07	49.7	COG1807	4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferase of PMT family	535
641665587	445	30.27	79	439	94	447	4.0e-43	169	COG5002	Signal transduction histidine kinase	459
641665588	234	36.05	1	233	5	234	6.0e-35	140	COG0704	Phosphate uptake regulator	240
641665589	261	68.8	12	261	5	253	3.0e-128	451	COG1117	ABC-type phosphate transport system, ATPase component	253
641665590	288	45.83	8	288	3	289	5.0e-66	244	COG0581	ABC-type phosphate transport system, permease component	292
641665591	322	46.73	18	318	16	308	1.0e-72	266	COG0573	ABC-type phosphate transport system, permease component	310
641665592	350	36.09	10	329	23	318	4.0e-55	208	COG0226	ABC-type phosphate transport system, periplasmic component	318
641665593	444	44.98	1	443	5	459	2.0e-111	395	COG1109	Phosphomannomutase	464
641665594	275	46.92	15	269	8	263	9.0e-67	247	COG0294	Dihydropteroate synthase	274
641665595	634	58.67	10	607	1	596	0.0e+00	750	COG0465	ATP-dependent Zn proteases	596
641665596	232	48.17	8	225	1	205	6.0e-61	227	COG0293	23S rRNA U2552 (ribose-2'-O)-methylase RlmE/FtsJ	205
641665597	135	44.93	1	69	22	90	5.0e-13	67.1	COG1534	RNA-binding protein YhbY	97
641665599	158	53.29	6	157	1	150	6.0e-36	143	COG0782	Transcription elongation factor, GreA/GreB family	151
641665600	1091	69.48	13	415	1	393	0.0e+00	568	COG0458	Carbamoylphosphate synthase large subunit	400
641665601	394	57.25	6	391	2	368	0.0e+00	563	COG0505	Carbamoylphosphate synthase small subunit	368
641665602	135	48.55	1	135	2	139	1.0e-30	125	COG3193	Uncharacterized conserved protein GlcG, DUF336 family	141
641665603	231	36.41	19	230	18	233	2.0e-24	105	COG0670	Integral membrane protein, interacts with FtsH	233
641665604	473	50.34	23	463	1	434	0.0e+00	532	COG0305	Replicative DNA helicase	435
641665605	150	58.39	1	149	1	148	2.0e-38	151	COG0359	Ribosomal protein L9	148
641665606	94	54.17	15	86	4	75	3.0e-18	83	COG0238	Ribosomal protein S18	75
641665607	102	33.7	2	91	5	96	5.0e-12	62.7	COG2965	Primosomal replication protein N	103
641665608	121	44.64	2	112	1	112	2.0e-30	124	COG0360	Ribosomal protein S6	112
641665610	90	29.07	2	87	13	98	2.0e-10	57.7	COG4327	Uncharacterized membrane protein	101
641665611	798	48.73	10	796	4	735	0.0e+00	715	COG0574	Phosphoenolpyruvate synthase/pyruvate phosphate dikinase	740
641665612	273	48.01	4	273	4	273	5.0e-80	290	COG1806	Regulator of PEP synthase PpsR, kinase-PPPase family (combines ADP:protein kinase and phosphorylase activities)	273
641665613	277	30.15	24	273	1	256	1.0e-40	160	COG0566	tRNA G18 (ribose-2'-O)-methylase SpoU	260
641665614	218	59.36	25	207	1	187	5.0e-63	234	COG0164	Ribonuclease HII	199
641665615	381	45.79	6	381	2	381	3.0e-108	385	COG0763	Lipid A disaccharide synthetase	381
641665616	264	53.79	1	264	3	260	4.0e-91	327	COG1043	Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase	260
641665617	148	54.05	1	146	1	145	4.0e-42	163	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
641665618	342	48.21	4	339	5	337	1.0e-87	316	COG1044	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase	338
641665619	174	29.34	5	167	3	169	6.0e-17	80.4	COG2825	Periplasmic chaperone for outer membrane proteins, Skp family	170
641665620	770	37.21	16	770	6	766	0.0e+00	601	COG4775	Outer membrane protein assembly factor BamA	766
641665622	402	54.73	11	401	2	384	0.0e+00	513	COG0743	1-deoxy-D-xylulose 5-phosphate reductoisomerase	385
641665623	278	35.74	1	277	1	262	3.0e-26	112	COG0575	CDP-diglyceride synthetase	265
641665624	257	49.59	1	240	2	245	6.0e-84	304	COG0020	Undecaprenyl pyrophosphate synthase	245
641665625	186	58.06	1	186	2	187	3.0e-62	231	COG0233	Ribosome recycling factor	187
641665626	236	59.75	1	235	2	237	8.0e-88	316	COG0528	Uridylate kinase	238
641665627	306	49.19	1	302	1	296	3.0e-76	278	COG0264	Translation elongation factor EF-Ts	296
641665628	248	55.1	3	247	4	247	8.0e-91	326	COG0052	Ribosomal protein S2	252
641665629	413	35.66	4	411	50	471	1.0e-73	270	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
641665630	455	25.16	1	454	5	383	8.0e-30	125	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
641665631	153	21.9	7	143	3	132	1.0e-06	46	COG1569	Predicted nucleic acid-binding protein, contains PIN domain	142
641665632	548	36.01	267	542	22	284	1.0e-35	145	COG0063	NAD(P)H-hydrate repair enzyme Nnr, NAD(P)H-hydrate dehydratase domain	284
641665632	548	39.2	41	237	20	202	1.0e-33	138	COG0062	NAD(P)H-hydrate repair enzyme Nnr, NAD(P)H-hydrate epimerase domain	203
641665633	733	44.28	1	660	67	704	0.0e+00	652	COG0557	Exoribonuclease R	706
641665635	173	33.96	7	164	3	154	2.0e-23	102	COG2236	Hypoxanthine phosphoribosyltransferase	192
641665636	445	58.03	9	443	1	429	0.0e+00	619	COG0104	Adenylosuccinate synthase	430
641665637	387	35.4	5	384	3	385	2.0e-61	230	COG3705	ATP phosphoribosyltransferase regulatory subunit HisZ	390
641665638	62	37.1	1	62	1	62	5.0e-06	42.5	COG3242	Uncharacterized conserved protein YjeT, DUF2065 family	62
641665639	295	28.12	3	285	2	284	1.0e-40	160	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
641665640	393	28.57	55	351	1	289	4.0e-43	169	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
641665641	412	54.97	9	370	3	354	2.0e-114	406	COG2262	50S ribosomal subunit-associated GTPase HflX	411
641665642	80	68	3	76	2	76	2.0e-23	100	COG1923	sRNA-binding regulator protein Hfq	77
641665643	448	48.32	1	445	2	444	0.0e+00	547	COG1160	Predicted GTPases	444
641665644	387	20.22	17	347	5	364	4.0e-12	66.4	COG1520	Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat	370
641665645	224	32.04	5	210	3	206	1.0e-30	126	COG2976	Putative negative regulator of RcsB-dependent stress response	207
641665646	433	47.66	2	419	1	421	0.0e+00	463	COG0124	Histidyl-tRNA synthetase	429
641665647	430	45.24	35	423	14	357	1.0e-120	426	COG0821	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase IspG/GcpE	361
641665648	299	23	22	268	5	284	3.0e-17	82.8	COG1426	Cytoskeletal protein RodZ, contains Xre-like HTH and DUF4115 domains	284
641665649	306	38.05	78	303	26	250	1.0e-41	163	COG3063	Tfp pilus assembly protein PilF	250
641665650	393	52.29	4	372	2	349	1.0e-123	436	COG0820	Adenine C2-methylase RlmN of 23S rRNA A2503 and tRNA A37	349
641665651	141	60.45	2	135	1	134	1.0e-53	202	COG0105	Nucleoside diphosphate kinase	135
641665652	736	42.62	288	526	1	243	8.0e-64	239	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
641665653	206	46.82	1	172	4	174	6.0e-41	160	COG1386	Chromosome segregation and condensation protein ScpB	184
641665654	369	42.57	45	342	6	288	1.0e-71	264	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
641665655	284	39.36	28	275	3	241	7.0e-51	194	COG4105	Outer membrane protein assembly factor BamD, BamD/ComL family	254
641665656	658	33.89	15	653	1	652	6.0e-108	385	COG1199	Rad3-related DNA helicase	654
641665658	255	29.72	9	252	7	252	5.0e-29	121	COG0631	Serine/threonine protein phosphatase PrpC	262
641665659	366	49.72	2	359	9	367	8.0e-122	430	COG1485	Predicted ATPase	367
641665660	475	46.35	1	465	1	454	0.0e+00	483	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
641665661	114	37.7	48	105	5	65	6.0e-09	52.9	COG1983	Phage shock protein PspC (stress-responsive transcriptional regulator)	70
641665662	413	51.8	2	412	1	404	4.0e-102	365	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
641665663	950	57.28	2	941	1	905	0.0e+00	1307	COG0567	2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes	906
641665665	256	43.32	12	253	1	246	2.0e-55	208	COG1414	DNA-binding transcriptional regulator, IclR family	246
641665667	513	50.48	3	413	1	406	8.0e-119	421	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
641665668	571	31.95	31	437	1	380	2.0e-88	320	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
641665669	280	39.42	23	261	2	234	7.0e-48	184	COG1183	Phosphatidylserine synthase	234
641665670	338	66.67	1	336	3	338	0.0e+00	541	COG0059	Ketol-acid reductoisomerase	338
641665671	163	54.04	1	161	3	163	5.0e-48	183	COG0440	Acetolactate synthase, small subunit	163
641665672	592	52.13	24	585	1	549	0.0e+00	670	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
641665673	188	22.87	1	187	11	181	3.0e-16	78.2	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641665677	126	49.59	4	126	1	123	5.0e-31	126	COG0818	Diacylglycerol kinase	123
641665678	112	72.32	1	112	1	112	3.0e-38	149	COG0347	Nitrogen regulatory protein PII	112
641665679	554	45.49	3	537	1	530	0.0e+00	554	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
641665682	1109	36.2	6	1109	2	1070	0.0e+00	964	COG0587	DNA polymerase III, alpha subunit	1139
641665683	168	34.03	25	161	2	139	3.0e-17	81.6	COG4968	Tfp pilus assembly protein PilE	139
641665684	212	20.31	13	204	7	174	7.0e-13	67.3	COG4970	Tfp pilus assembly protein FimT	181
641665688	1309	25.63	539	1307	252	1035	1.0e-70	262	COG3419	Tfp pilus assembly protein, tip-associated adhesin PilY1	1036
641665690	311	45.11	1	310	2	311	4.0e-79	288	COG0123	Acetoin utilization deacetylase AcuC or a related deacetylase	340
641665691	349	47.96	46	331	15	307	1.0e-65	243	COG0714	MoxR-like ATPase	329
641665692	362	19.2	52	362	9	303	2.0e-12	66.7	COG1721	Uncharacterized conserved protein, DUF58 family, contains vWF domain	416
641665694	132	26.76	1	129	1	138	5.0e-12	63.3	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
641665696	576	36.93	4	576	1	567	2.0e-114	406	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
641665697	207	48.79	1	207	4	210	3.0e-54	205	COG0800	2-keto-3-deoxy-6-phosphogluconate aldolase	211
641665698	614	36.85	7	612	4	570	0.0e+00	561	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
641665699	242	42.2	45	215	8	180	7.0e-34	137	COG3703	Cation transport regulator ChaC	190
641665700	216	34.54	10	198	8	194	1.0e-22	99.6	COG2068	CTP:molybdopterin cytidylyltransferase MocA	199
641665701	211	57.75	1	211	2	214	9.0e-76	276	COG0259	Pyridoxine/pyridoxamine 5'-phosphate oxidase	214
641665702	191	49.11	18	182	7	174	9.0e-59	219	COG0225	Peptide methionine sulfoxide reductase MsrA	174
641665703	271	25.3	25	271	2	219	8.0e-13	67.9	COG1434	Uncharacterized SAM-binding protein YcdF, DUF218 family	223
641665704	524	47.68	1	518	1	473	0.0e+00	571	COG0043	3-polyprenyl-4-hydroxybenzoate decarboxylase	477
641665706	415	68.28	4	414	2	412	0.0e+00	656	COG0112	Glycine/serine hydroxymethyltransferase	413
641665707	147	53.06	1	147	1	147	2.0e-46	178	COG1327	Transcriptional regulator NrdR, contains Zn-ribbon and ATP-cone domains	156
641665708	188	20.97	10	188	2	181	4.0e-11	61.2	COG4970	Tfp pilus assembly protein FimT	181
641665709	149	32.58	5	134	6	137	7.0e-16	76.6	COG4968	Tfp pilus assembly protein PilE	139
641665712	393	30.47	2	123	7	134	3.0e-07	50	COG4967	Tfp pilus assembly protein PilV	162
641665713	416	38.84	170	406	1	218	6.0e-46	178	COG1985	Pyrimidine reductase, riboflavin biosynthesis	218
641665713	416	60.14	21	168	2	145	1.0e-47	184	COG0117	Pyrimidine deaminase domain of riboflavin biosynthesis protein RibD	146
641665714	363	31.79	204	363	1	172	7.0e-28	118	COG0807	GTP cyclohydrolase II	193
641665714	363	58.33	1	204	1	203	9.0e-80	290	COG0108	3,4-dihydroxy-2-butanone 4-phosphate synthase	203
641665715	154	46.53	12	151	8	151	1.0e-37	148	COG0054	6,7-dimethyl-8-ribityllumazine synthase (Riboflavin synthase beta chain)	152
641665716	171	44.22	25	164	5	151	3.0e-34	138	COG0781	Transcription termination factor NusB	151
641665717	396	41.31	5	393	1	390	7.0e-97	347	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
641665718	445	30.74	76	333	2	279	5.0e-41	162	COG0515	Serine/threonine protein kinase	384
641665719	145	45.04	15	145	5	134	5.0e-32	129	COG0824	Acyl-CoA thioesterase FadM	137
641665720	236	41.86	10	224	1	215	1.0e-48	186	COG0811	Biopolymer transport protein ExbB/TolQ	216
641665721	156	36.18	3	152	2	133	1.0e-23	102	COG0848	Biopolymer transport protein ExbD	137
641665723	466	28.17	120	399	71	344	7.0e-37	148	COG2206	HD-GYP domain, c-di-GMP phosphodiesterase class II (or its inactivated variant)	344
641665725	100	37.04	11	88	11	91	3.0e-12	63.4	COG2388	Predicted acetyltransferase, GNAT superfamily	99
641665726	374	40.13	64	374	35	343	2.0e-49	190	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
641665728	295	51.04	1	288	5	291	6.0e-70	257	COG2962	Uncharacterized membrane protein RarD, contains two EamA domains	293
641665729	445	26.2	38	290	22	273	1.0e-19	91.5	COG2358	TRAP-type uncharacterized transport system, periplasmic component	321
641665730	136	39.39	1	132	1	131	7.0e-26	109	COG1487	Predicted nucleic acid-binding protein, contains PIN domain	133
641665731	77	43.24	4	77	3	74	6.0e-15	72.3	COG4456	Virulence-associated protein VagC (function unknown)	74
641665734	159	53.59	1	151	2	149	1.0e-53	202	COG3865	Glyoxalase superfamily enzyme, possibly 3-demethylubiquinone-9 3-methyltransferase	151
641665736	211	31.19	4	197	2	203	8.0e-23	100	COG0625	Glutathione S-transferase	211
641665738	351	27.57	119	320	54	255	3.0e-18	86.6	COG1864	DNA/RNA endonuclease G, NUC1	281
641665739	82	38.55	1	81	4	84	1.0e-16	77.6	COG4115	Toxin component of the Txe-Axe toxin-antitoxin module, Txe/YoeB family	84
641665740	80	37.35	1	80	3	85	4.0e-09	53.1	COG2161	Antitoxin component YafN of the YafNO toxin-antitoxin module, PHD/YefM family	86
641665741	606	29.92	171	534	6	364	2.0e-51	197	COG0006	Xaa-Pro aminopeptidase	384
641665742	596	27.15	170	527	45	408	2.0e-29	123	COG0840	Methyl-accepting chemotaxis protein	408
641665744	577	32.09	18	282	5	245	1.0e-32	134	COG0388	Predicted amidohydrolase	274
641665744	577	41.55	294	568	1	268	4.0e-73	269	COG0171	NH3-dependent NAD+ synthetase	268
641665745	381	51.07	1	369	19	385	2.0e-112	398	COG3146	Predicted N-acyltransferase	387
641665747	597	42.9	13	594	1	594	0.0e+00	554	COG4178	ABC-type uncharacterized transport system, permease and ATPase components	604
641665748	179	52.57	1	175	1	171	7.0e-53	200	COG0221	Inorganic pyrophosphatase	171
641665749	712	60.89	4	676	3	699	0.0e+00	744	COG3808	Na+ or H+-translocating membrane pyrophosphatase	703
641665750	413	56.52	1	413	1	409	0.0e+00	581	COG4553	Poly-beta-hydroxyalkanoate depolymerase	415
641665751	224	53.7	10	167	37	198	2.0e-42	165	COG2878	Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit	198
641665752	303	23.92	42	277	32	286	2.0e-16	80.4	COG0657	Acetyl esterase/lipase	312
641665754	429	21.82	115	414	15	309	6.0e-06	45.7	COG0582	Integrase	309
641665760	271	35.69	1	269	9	291	9.0e-44	170	COG4643	Uncharacterized domain associated with phage/plasmid primase	366
641665769	359	47.32	3	356	2	347	2.0e-123	435	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
641665770	545	33.67	14	495	2	487	2.0e-103	369	COG2368	Aromatic ring hydroxylase	493
641665771	181	20.1	4	157	1	194	6.0e-08	50.6	COG1335	Nicotinamidase-related amidase	205
641665772	282	31.42	1	220	21	243	4.0e-49	188	COG1718	Serine/threonine-protein kinase RIO1	268
641665774	477	36.72	21	473	30	492	3.0e-107	382	COG0513	Superfamily II DNA and RNA helicase	513
641665775	753	50.63	18	734	3	708	0.0e+00	730	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
641665777	362	24.11	85	300	25	225	2.0e-06	47.3	COG2801	Transposase InsO and inactivated derivatives	232
641665779	326	39.06	1	319	14	318	3.0e-70	259	COG2826	Transposase and inactivated derivatives, IS30 family	318
641665780	326	39.06	1	319	14	318	3.0e-70	259	COG2826	Transposase and inactivated derivatives, IS30 family	318
641665781	474	40.73	15	474	8	457	7.0e-86	311	COG0277	FAD/FMN-containing dehydrogenase	459
641665782	353	38.94	1	352	4	328	3.0e-56	212	COG2070	NAD(P)H-dependent flavin oxidoreductase YrpB, nitropropane dioxygenase family	336
641665785	236	35.29	10	180	1	184	4.0e-29	121	COG3658	Cytochrome b	192
641665786	221	42.61	1	220	1	229	2.0e-52	199	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
641665787	475	30.98	145	469	23	334	4.0e-32	132	COG0642	Signal transduction histidine kinase	336
641665788	557	27.59	11	554	4	510	9.0e-79	288	COG0737	2',3'-cyclic-nucleotide 2'-phosphodiesterase/5'- or 3'-nucleotidase, 5'-nucleotidase family	517
641665789	360	56.32	1	360	3	365	0.0e+00	480	COG1932	Phosphoserine aminotransferase	365
641665790	402	38.85	47	317	60	322	5.0e-50	192	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
641665791	351	25.17	21	299	2	287	2.0e-19	90.3	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
641665795	239	33.48	6	225	2	221	1.0e-29	123	COG1802	DNA-binding transcriptional regulator, GntR family	230
641665796	232	34.76	14	193	1	176	2.0e-29	123	COG1335	Nicotinamidase-related amidase	205
641665797	559	42.94	17	543	5	501	0.0e+00	497	COG3845	ABC-type uncharacterized transport system, ATPase component	501
641665798	233	32.72	21	230	2	202	2.0e-34	139	COG1335	Nicotinamidase-related amidase	205
641665799	307	40.57	13	292	8	288	4.0e-57	215	COG1079	ABC-type uncharacterized transport system, permease component	304
641665800	370	34.55	17	370	4	356	2.0e-53	203	COG4603	ABC-type uncharacterized transport system, permease component	356
641665801	381	33.04	14	349	6	342	1.0e-58	220	COG1744	Basic membrane lipoprotein Med, periplasmic binding protein (PBP1-ABC) superfamily	345
641665803	467	40.89	1	455	1	465	1.0e-98	353	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
641665806	621	35.52	24	475	8	475	2.0e-75	277	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
641665811	596	33.33	299	592	99	385	4.0e-46	179	COG3497	Phage tail sheath protein FI	394
641665830	534	25.16	366	524	44	189	5.0e-16	79.5	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
641665834	265	38.11	7	264	5	268	2.0e-49	189	COG4727	Uncharacterized protein	287
641665836	172	27.54	95	163	13	81	3.0e-07	48.1	COG4298	Uncharacterized protein	95
641665838	658	45.12	71	644	1	528	0.0e+00	640	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
641665839	197	40.86	6	191	2	164	7.0e-34	137	COG2862	Uncharacterized membrane protein YqhA	169
641665840	508	47.56	1	304	1	297	6.0e-103	368	COG1951	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain	297
641665840	508	52.54	318	494	2	178	1.0e-63	237	COG1838	Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain	184
641665842	256	37.66	32	256	66	289	4.0e-50	191	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
641665843	343	37.16	20	343	4	314	7.0e-48	184	COG0451	Nucleoside-diphosphate-sugar epimerase	314
641665844	426	39.07	1	421	9	433	2.0e-116	413	COG0677	UDP-N-acetyl-D-mannosaminuronate dehydrogenase	436
641665845	386	22.07	18	309	42	328	7.0e-15	75.4	COG5653	Acetyltransferase involved in cellulose biosynthesis, CelD/BcsL family	406
641665846	393	16.43	2	342	28	355	8.0e-08	51.9	COG5653	Acetyltransferase involved in cellulose biosynthesis, CelD/BcsL family	406
641665847	351	17.93	13	339	19	367	7.0e-25	108	COG4763	Uncharacterized membrane protein YcfT	388
641665848	491	20.72	1	473	4	468	6.0e-16	79.4	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
641665850	374	24.18	7	360	17	381	2.0e-23	103	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
641665854	336	31.69	1	334	1	313	1.0e-54	207	COG0451	Nucleoside-diphosphate-sugar epimerase	314
641665855	372	28.5	1	367	1	374	3.0e-38	152	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
641665859	379	28.05	11	375	4	381	2.0e-37	150	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
641665860	409	27.25	54	395	18	367	2.0e-30	127	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
641665861	255	29.58	16	254	4	223	5.0e-14	71.8	COG1434	Uncharacterized SAM-binding protein YcdF, DUF218 family	223
641665864	278	35.16	12	228	2	211	1.0e-33	136	COG3279	DNA-binding response regulator, LytR/AlgR family	244
641665866	476	56.2	9	476	2	458	0.0e+00	599	COG0165	Argininosuccinate lyase	459
641665871	577	25.35	63	547	115	574	1.0e-53	204	COG1450	Type II secretory pathway component GspD/PulD (secretin)	587
641665872	578	45.97	64	572	3	497	0.0e+00	500	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
641665873	412	38.39	1	408	1	395	3.0e-89	322	COG1459	Type II secretory pathway, component PulF	397
641665877	157	21.33	3	137	2	149	2.0e-06	45	COG2165	Type II secretory pathway, pseudopilin PulG	149
641665881	606	31.96	39	606	155	773	0.0e+00	500	COG4993	Glucose dehydrogenase	773
641665886	277	29.53	9	157	5	148	4.0e-15	75.5	COG5501	Predicted secreted protein	148
641665888	310	29.57	8	294	1	300	3.0e-25	109	COG3391	DNA-binding beta-propeller fold protein YncE	381
641665891	287	31.2	44	168	28	148	3.0e-15	75.9	COG5501	Predicted secreted protein	148
641665893	342	41.12	1	336	9	336	2.0e-76	279	COG0798	Arsenite efflux pump ArsB, ACR3 family	342
641665894	168	32.43	1	146	1	139	1.0e-25	109	COG0394	Protein-tyrosine-phosphatase	139
641665896	108	33.66	1	101	10	108	3.0e-10	57.1	COG0640	DNA-binding transcriptional regulator, ArsR family	110
641665898	360	26.84	79	349	1	226	7.0e-15	75.2	COG3039	Transposase and inactivated derivatives, IS5 family	230
641665903	270	30.08	153	269	7	127	2.0e-07	49.5	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
641665905	347	25.91	83	296	23	224	4.0e-09	56.1	COG2801	Transposase InsO and inactivated derivatives	232
641665906	225	25.79	1	221	5	202	3.0e-27	115	COG0560	Phosphoserine phosphatase	212
641665907	181	44.3	28	175	17	160	6.0e-34	137	COG1795	Formaldehyde-activating enzyme nesessary for methanogenesis	170
641665908	281	32.7	1	208	1	211	8.0e-34	137	COG2218	Formylmethanofuran dehydrogenase subunit C	264
641665909	315	49.33	10	307	1	297	3.0e-86	312	COG2037	Formylmethanofuran:tetrahydromethanopterin formyltransferase	297
641665910	561	38.53	1	531	2	553	0.0e+00	480	COG1229	Formylmethanofuran dehydrogenase subunit A	575
641665911	433	26.85	22	388	7	399	6.0e-24	105	COG1029	Formylmethanofuran dehydrogenase subunit B	429
641665912	252	29.07	1	247	1	228	1.0e-22	100	COG1411	Uncharacterized protein related to proFAR isomerase (HisA)	229
641665913	343	25.84	1	328	1	277	3.0e-23	102	COG1821	Predicted ATP-dependent carboligase, ATP-grasp superfamily	307
641665914	383	29.9	15	314	5	294	6.0e-46	178	COG1548	Uncharacterized protein, hydantoinase/oxoprolinase family	330
641665916	252	31.8	21	250	1	234	5.0e-21	95	COG1891	Uncharacterized protein, UPF0264 family	235
641665917	195	19.23	1	174	10	189	4.0e-10	58	COG2457	Uncharacterized protein	199
641665920	705	40.55	10	591	7	555	2.0e-126	447	COG3284	Transcriptional regulator of acetoin/glycerol metabolism	606
641665921	176	32.77	25	142	2	120	2.0e-19	88.7	COG1539	Dihydroneopterin aldolase	121
641665922	169	53.37	6	168	2	164	2.0e-48	184	COG1795	Formaldehyde-activating enzyme nesessary for methanogenesis	170
641665923	298	25.61	27	294	25	281	3.0e-13	69.6	COG1767	Triphosphoribosyl-dephospho-CoA synthetase	288
641665924	332	29.03	1	303	23	309	4.0e-33	135	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
641665925	334	40.57	13	327	1	309	1.0e-75	277	COG3252	Methenyltetrahydromethanopterin cyclohydrolase	314
641665926	415	22.98	13	395	13	371	2.0e-19	90.5	COG2232	Predicted ATP-dependent carboligase, ATP-grasp superfamily	389
641665928	375	28.66	20	351	1	311	7.0e-46	178	COG1907	Predicted archaeal sugar kinase	312
641665929	198	40.12	30	189	4	165	3.0e-37	148	COG1247	L-amino acid N-acyltransferase YncA	169
641665930	284	23.66	1	269	18	278	2.0e-33	136	COG0714	MoxR-like ATPase	329
641665932	194	26.82	9	183	10	186	1.0e-15	76.5	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
641665933	668	25.91	6	660	3	616	4.0e-75	276	COG1506	Dipeptidyl aminopeptidase/acylaminoacyl peptidase	620
641665935	393	61.36	1	393	1	392	0.0e+00	518	COG3825	Uncharacterized conserved protein,  contains von Willebrand factor type A (vWA) domain	393
641665936	646	26.25	39	646	11	594	1.0e-63	238	COG0729	Outer membrane translocation and assembly module TamA	594
641665937	1453	22.14	10	1441	3	1274	6.0e-78	286	COG2911	Autotransporter translocation and assembly factor TamB	1278
641665939	429	20.61	126	414	16	307	9.0e-10	58.4	COG0582	Integrase	309
641665941	99	28.71	1	99	1	99	6.0e-06	42.5	COG2963	Transposase and inactivated derivatives	116
641665942	295	36.91	56	288	19	232	4.0e-23	101	COG2801	Transposase InsO and inactivated derivatives	232
641665945	200	37.81	17	199	4	200	9.0e-28	116	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
641665948	696	42.78	507	684	3	181	2.0e-39	157	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
641665949	1087	32.97	513	790	59	326	4.0e-39	157	COG0642	Signal transduction histidine kinase	336
641665950	309	28.52	9	305	5	296	4.0e-36	145	COG0583	DNA-binding transcriptional regulator, LysR family	297
641665951	358	47.61	1	354	1	346	1.0e-125	443	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
641665952	428	62.71	1	420	1	421	0.0e+00	530	COG2379	Glycerate-2-kinase	422
641665953	328	41.32	10	325	3	317	9.0e-74	270	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
641665954	365	30.09	12	340	10	355	9.0e-45	174	COG0484	DnaJ-class molecular chaperone with C-terminal Zn finger domain	371
641665955	522	37.37	143	513	13	408	3.0e-44	173	COG0840	Methyl-accepting chemotaxis protein	408
641665956	242	35.54	5	241	4	245	2.0e-54	206	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
641665965	533	20.14	3	533	5	537	3.0e-29	123	COG2303	Choline dehydrogenase or related flavoprotein	542
641665967	268	40.71	22	268	9	250	1.0e-32	133	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
641665968	309	27.99	18	307	6	281	4.0e-21	95.5	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
641665969	600	34.08	130	306	4	181	2.0e-18	87.5	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
641665969	600	34.96	331	596	3	256	3.0e-49	190	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
641665970	223	33.64	5	217	1	205	7.0e-28	117	COG0135	Phosphoribosylanthranilate isomerase	208
641665971	325	30.83	186	305	8	127	5.0e-24	105	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
641665972	414	52.27	23	413	7	394	5.0e-119	421	COG4214	ABC-type xylose transport system, permease component	394
641665973	507	51.29	1	503	5	497	0.0e+00	597	COG1129	ABC-type sugar transport system, ATPase component	500
641665974	354	49.15	1	354	1	339	1.0e-113	403	COG4213	ABC-type xylose transport system, periplasmic component	341
641665975	564	39.46	6	560	3	531	0.0e+00	514	COG1069	Ribulose kinase	544
641665976	244	38.53	11	241	4	218	2.0e-52	199	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
641665977	497	57.14	1	497	1	494	0.0e+00	648	COG2160	L-arabinose isomerase	497
641665978	317	31.15	193	314	4	124	1.0e-18	87.2	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
641665979	267	63.6	5	259	3	256	2.0e-103	368	COG4813	Trehalose utilization protein	261
641665980	369	34.67	26	369	2	340	2.0e-58	219	COG0673	Predicted dehydrogenase	342
641665981	401	23.83	36	390	20	398	5.0e-15	75.6	COG0738	Fucose permease	422
641665982	261	62.4	20	261	1	240	1.0e-101	363	COG1126	ABC-type polar amino acid transport system, ATPase component	240
641665983	216	44.39	4	216	9	222	4.0e-53	201	COG0765	ABC-type amino acid transport system, permease component	222
641665984	225	42.13	1	215	3	218	4.0e-47	181	COG0765	ABC-type amino acid transport system, permease component	222
641665985	263	29.55	6	258	4	267	7.0e-28	117	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
641665986	460	24.68	13	452	5	432	3.0e-38	153	COG1541	Phenylacetate-coenzyme A ligase PaaK, adenylate-forming domain family	438
641665987	605	40.36	161	602	9	443	4.0e-107	382	COG3243	Poly(3-hydroxyalkanoate) synthetase	445
641665988	668	25.08	14	597	2	477	8.0e-40	159	COG0737	2',3'-cyclic-nucleotide 2'-phosphodiesterase/5'- or 3'-nucleotidase, 5'-nucleotidase family	517
641665990	579	37.5	167	516	33	408	2.0e-50	194	COG0840	Methyl-accepting chemotaxis protein	408
641665991	821	34.93	51	774	33	737	0.0e+00	605	COG1501	Alpha-glucosidase, glycosyl hydrolase family GH31	772
641665992	434	47.89	51	429	1	378	2.0e-82	300	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
641665993	176	31.17	1	154	4	154	3.0e-20	91.5	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
641665994	324	41.95	1	324	2	330	2.0e-89	322	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
641665995	531	47.56	17	530	13	522	0.0e+00	485	COG0578	Glycerol-3-phosphate dehydrogenase	532
641665996	257	41.9	4	256	2	253	9.0e-68	250	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
641665997	497	60.53	1	494	4	493	0.0e+00	728	COG0554	Glycerol kinase	499
641665998	417	22.55	23	393	7	380	1.0e-10	61.4	COG0475	Kef-type K+ transport system, membrane component KefB	397
641665999	374	41.48	11	372	2	365	3.0e-105	375	COG2170	Gamma-glutamyl:cysteine ligase YbdK, ATP-grasp superfamily	369
641666000	285	41.23	26	253	5	219	6.0e-52	197	COG2071	Gamma-glutamyl-gamma-aminobutyrate hydrolase PuuD (putrescine degradation), contains GATase1-like domain	243
641666001	362	41.76	15	353	1	331	9.0e-78	284	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
641666003	875	16.59	34	875	7	768	2.0e-23	105	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
641666004	401	23.33	1	399	1	395	4.0e-20	93	COG0475	Kef-type K+ transport system, membrane component KefB	397
641666006	146	32.84	10	143	3	135	5.0e-22	97.2	COG0848	Biopolymer transport protein ExbD	137
641666007	142	42.19	12	139	9	135	6.0e-27	113	COG0848	Biopolymer transport protein ExbD	137
641666008	278	34.78	67	267	1	205	3.0e-29	122	COG0811	Biopolymer transport protein ExbB/TolQ	216
641666011	343	34.91	1	332	3	333	4.0e-66	245	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
641666012	358	37.95	55	357	47	333	5.0e-50	192	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
641666013	474	38.24	7	473	2	441	2.0e-121	429	COG1486	Alpha-galactosidase/6-phospho-beta-glucosidase, family 4 of glycosyl hydrolase	442
641666014	434	25.11	8	434	16	431	9.0e-31	128	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
641666015	308	35.59	16	308	3	281	1.0e-55	210	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
641666016	317	40.83	28	313	3	291	4.0e-59	222	COG1175	ABC-type sugar transport system, permease component	295
641666017	344	35.84	1	344	3	332	1.0e-65	244	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
641666018	390	49.73	1	370	1	337	1.0e-115	410	COG3839	ABC-type sugar transport system, ATPase component	338
641666019	673	33.58	3	670	18	670	6.0e-125	441	COG1874	Beta-galactosidase GanA	673
641666020	728	31.11	16	670	2	650	4.0e-120	425	COG3345	Alpha-galactosidase	687
641666021	338	47.48	2	336	1	329	0.0e+00	490	COG1087	UDP-glucose 4-epimerase	329
641666022	350	53.82	13	348	1	336	3.0e-106	378	COG1085	Galactose-1-phosphate uridylyltransferase	338
641666023	387	50.26	1	385	1	387	5.0e-120	424	COG0153	Galactokinase	390
641666024	337	40.37	18	335	2	309	2.0e-75	276	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
641666025	236	44.64	7	229	2	223	1.0e-64	239	COG1136	ABC-type lipoprotein export system, ATPase component	226
641666026	406	16.79	14	406	2	418	5.0e-10	59.4	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
641666028	199	25.52	1	192	4	193	1.0e-06	46.6	COG1309	DNA-binding transcriptional regulator, AcrR family	201
641666029	372	65.32	1	372	1	366	0.0e+00	553	COG1062	Zn-dependent alcohol dehydrogenase	366
641666030	288	39.42	4	288	5	315	2.0e-61	229	COG0627	S-formylglutathione hydrolase FrmB	316
641666031	446	31.31	9	431	3	420	3.0e-43	169	COG0038	H+/Cl- antiporter ClcA	443
641666032	424	24.58	16	423	2	386	1.0e-53	204	COG0247	Fe-S oxidoreductase	388
641666033	376	23.58	8	376	44	459	1.0e-30	127	COG0277	FAD/FMN-containing dehydrogenase	459
641666034	512	39.18	37	488	1	459	3.0e-86	312	COG0277	FAD/FMN-containing dehydrogenase	459
641666035	419	28.3	11	416	10	386	5.0e-28	119	COG4398	Small ligand-binding sensory domain FIST	389
641666037	329	29.35	62	324	31	298	6.0e-24	104	COG3735	Uncharacterized conserved protein YbaP, TraB family	299
641666038	328	23.53	7	328	4	266	3.0e-18	86.6	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
641666041	795	25.87	332	789	20	491	2.0e-30	127	COG0464	AAA+-type ATPase, SpoVK/Ycf46/Vps4 family	494
641666042	357	57.36	14	338	2	309	5.0e-113	401	COG0646	Methionine synthase I (cobalamin-dependent), methyltransferase domain	311
641666043	155	28.37	1	134	19	158	3.0e-07	47.9	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
641666044	924	55.77	13	893	6	842	0.0e+00	1084	COG1410	Methionine synthase I, cobalamin-binding domain	842
641666048	372	55.01	5	372	3	369	1.0e-123	436	COG0263	Glutamate 5-kinase	369
641666049	369	54.59	1	366	1	369	0.0e+00	485	COG0536	GTPase involved in cell partioning and DNA repair	369
641666050	85	71.76	1	85	1	84	1.0e-28	117	COG0211	Ribosomal protein L27	87
641666051	103	55.34	1	103	1	103	1.0e-32	131	COG0261	Ribosomal protein L21	103
641666052	313	41.25	1	313	7	322	1.0e-76	279	COG0142	Geranylgeranyl pyrophosphate synthase	322
641666054	92	44.32	1	86	1	88	3.0e-18	83.4	COG1254	Acylphosphatase	92
641666057	342	32.74	7	339	3	337	6.0e-48	185	COG0673	Predicted dehydrogenase	342
641666058	331	32.07	1	331	3	340	3.0e-48	185	COG0673	Predicted dehydrogenase	342
641666059	276	54.48	4	271	5	271	4.0e-88	318	COG4130	Predicted sugar epimerase, xylose isomerase-like family	272
641666060	377	22.77	13	357	3	312	3.0e-20	92.9	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
641666062	292	30.4	10	278	1	262	3.0e-50	192	COG1737	DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains	281
641666064	265	34.5	2	251	15	265	2.0e-61	228	COG0413	Ketopantoate hydroxymethyltransferase	268
641666065	282	56.23	4	282	7	287	1.0e-112	399	COG0788	Formyltetrahydrofolate hydrolase	287
641666067	248	50.21	1	235	7	245	4.0e-56	211	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
641666068	889	44.06	24	888	30	914	0.0e+00	791	COG0474	Magnesium-transporting ATPase (P-type)	917
641666069	318	30.74	5	312	12	319	4.0e-46	178	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
641666071	258	37	3	220	77	287	5.0e-47	181	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
641666072	480	33.12	2	454	18	476	9.0e-82	298	COG1621	Sucrose-6-phosphate hydrolase SacC, GH32 family	486
641666073	388	35.61	18	365	1	332	2.0e-63	236	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
641666074	421	25.29	11	417	13	433	6.0e-32	132	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
641666075	374	41.39	126	369	50	291	1.0e-55	210	COG1175	ABC-type sugar transport system, permease component	295
641666076	291	35.44	11	290	10	281	3.0e-48	185	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
641666077	334	51.18	1	327	1	335	2.0e-117	415	COG3839	ABC-type sugar transport system, ATPase component	338
641666078	103	38.46	1	102	2	105	3.0e-23	100	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
641666079	358	31.85	46	357	21	334	2.0e-51	196	COG3239	Fatty acid desaturase	343
641666080	350	30.03	10	350	3	312	8.0e-33	134	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
641666083	293	26.94	7	293	1	292	2.0e-28	119	COG0583	DNA-binding transcriptional regulator, LysR family	297
641666084	120	64.6	2	114	8	120	3.0e-43	167	COG3651	Uncharacterized conserved protein, DUF2237 family	125
641666085	396	43.17	209	391	4	181	1.0e-38	154	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
641666086	341	47.27	16	340	1	314	8.0e-58	217	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
641666087	515	52.62	21	514	4	498	0.0e+00	646	COG1129	ABC-type sugar transport system, ATPase component	500
641666088	309	40	4	309	15	319	3.0e-44	172	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
641666089	646	29.94	13	341	1	311	5.0e-49	189	COG0524	Sugar or nucleoside kinase, ribokinase family	311
641666089	646	55.19	339	643	1	303	3.0e-111	396	COG3892	Myo-inositol catabolism protein IolC	310
641666090	618	62	1	617	9	615	0.0e+00	841	COG3962	TPP-dependent trihydroxycyclohexane-1,2-dione (THcHDO) dehydratase, myo-inositol metabolism	617
641666091	309	30.52	7	306	1	274	3.0e-34	139	COG1082	Sugar phosphate isomerase/epimerase	274
641666092	265	60.53	1	263	1	266	2.0e-111	395	COG3718	5-deoxy-D-glucuronate isomerase	270
641666094	361	28.53	8	358	4	340	3.0e-45	175	COG0673	Predicted dehydrogenase	342
641666096	728	58.52	97	720	1	626	0.0e+00	791	COG0296	1,4-alpha-glucan branching enzyme	628
641666097	672	25.53	145	645	26	505	2.0e-39	157	COG0366	Glycosidase	505
641666098	570	46.24	9	538	1	505	1.0e-114	407	COG0366	Glycosidase	505
641666099	378	47.81	1	366	1	338	3.0e-116	411	COG3839	ABC-type sugar transport system, ATPase component	338
641666100	556	38.55	18	527	1	501	3.0e-94	339	COG0366	Glycosidase	505
641666101	547	38.3	12	512	1	495	2.0e-93	336	COG0366	Glycosidase	505
641666102	278	40	1	277	3	281	5.0e-60	224	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
641666103	304	34.54	1	302	5	294	3.0e-56	212	COG1175	ABC-type sugar transport system, permease component	295
641666104	423	27.13	1	420	5	431	1.0e-34	140	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
641666105	616	34.55	337	610	5	279	3.0e-48	187	COG1737	DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains	281
641666105	616	43.71	11	327	4	320	2.0e-87	317	COG0837	Glucokinase	320
641666106	379	29.18	29	377	20	307	4.0e-38	152	COG2017	Galactose mutarotase or related enzyme	308
641666107	505	39.29	13	491	1	471	1.0e-121	430	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
641666108	314	33.01	10	310	3	293	1.0e-29	123	COG0583	DNA-binding transcriptional regulator, LysR family	297
641666109	258	28.94	8	239	9	228	2.0e-20	93.4	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
641666110	474	20.94	56	468	12	452	5.0e-21	96.2	COG4783	Putative Zn-dependent protease, contains TPR repeats	484
641666112	272	41	4	241	4	226	8.0e-49	187	COG2013	Uncharacterized conserved protein, AIM24 family	227
641666113	144	39.86	1	144	4	151	4.0e-18	83.9	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
641666114	63	39.06	1	63	1	64	6.0e-12	62.3	COG1942	Phenylpyruvate tautomerase PptA, 4-oxalocrotonate tautomerase family	69
641666115	345	22.62	6	330	1	334	7.0e-44	171	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
641666116	305	55.88	2	293	3	305	2.0e-95	342	COG4569	Acetaldehyde dehydrogenase (acetylating)	310
641666117	262	43.68	3	262	2	262	1.0e-56	213	COG3971	2-keto-4-pentenoate hydratase	264
641666118	260	43.3	1	260	2	262	9.0e-65	240	COG3971	2-keto-4-pentenoate hydratase	264
641666119	289	33.58	35	283	19	280	1.0e-24	107	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
641666120	286	31.83	1	285	6	288	7.0e-27	114	COG0583	DNA-binding transcriptional regulator, LysR family	297
641666121	380	36.39	18	371	1	355	5.0e-57	215	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
641666122	330	28.46	63	323	1	248	3.0e-40	159	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
641666123	293	27.36	2	293	1	289	2.0e-19	90.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
641666126	426	29.58	22	425	4	424	1.0e-40	161	COG1055	Na+/H+ antiporter NhaD or related arsenite permease	424
641666128	112	28.24	24	108	14	97	3.0e-06	43.7	COG1669	Predicted nucleotidyltransferase	97
641666129	484	42.2	6	484	3	469	3.0e-125	442	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
641666130	151	43.48	14	150	7	140	3.0e-21	94.2	COG3193	Uncharacterized conserved protein GlcG, DUF336 family	141
641666133	354	28.89	13	322	48	393	9.0e-39	154	COG2871	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrF	410
641666140	247	26.58	27	247	13	230	9.0e-29	120	COG1802	DNA-binding transcriptional regulator, GntR family	230
641666141	762	32.81	300	615	38	333	6.0e-40	159	COG0642	Signal transduction histidine kinase	336
641666142	312	41.49	34	312	11	283	2.0e-62	233	COG2897	3-mercaptopyruvate sulfurtransferase SseA, contains two rhodanese domains	285
641666144	381	28.74	33	379	1	256	5.0e-33	135	COG0584	Glycerophosphoryl diester phosphodiesterase	257
641666145	388	23.04	23	382	2	356	1.0e-42	167	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
641666146	81	40.68	11	69	6	64	4.0e-09	53	COG1722	Exonuclease VII small subunit	81
641666147	298	42.96	4	269	1	259	1.0e-62	233	COG0142	Geranylgeranyl pyrophosphate synthase	322
641666148	639	61.99	5	630	3	627	0.0e+00	933	COG1154	Deoxyxylulose-5-phosphate synthase	627
641666149	347	30.39	1	328	1	359	5.0e-53	201	COG0484	DnaJ-class molecular chaperone with C-terminal Zn finger domain	371
641666150	146	25	1	146	1	146	5.0e-18	83.5	COG0071	Molecular chaperone IbpA, HSP20 family	146
641666151	130	25.44	18	130	33	146	2.0e-13	68.5	COG0071	Molecular chaperone IbpA, HSP20 family	146
641666152	106	42.27	5	101	7	103	2.0e-16	77.3	COG2863	Cytochrome c553	121
641666153	422	23.54	7	420	8	397	3.0e-40	159	COG2133	Glucose/arabinose dehydrogenase, beta-propeller fold	399
641666154	651	34.74	11	645	8	600	4.0e-107	382	COG3284	Transcriptional regulator of acetoin/glycerol metabolism	606
641666155	357	47.25	13	356	36	371	3.0e-91	328	COG4324	Predicted aminopeptidase	376
641666156	707	29.91	2	707	14	764	7.0e-121	428	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
641666157	402	45.59	9	401	4	392	1.0e-122	433	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
641666159	206	26.79	1	202	4	211	6.0e-17	81.1	COG1011	FMN phosphatase YigB, HAD superfamily	229
641666160	545	46.63	52	536	7	445	0.0e+00	489	COG0166	Glucose-6-phosphate isomerase	446
641666161	315	37.14	4	314	1	239	4.0e-59	222	COG0176	Transaldolase	239
641666162	485	50.82	1	484	6	483	0.0e+00	602	COG0364	Glucose-6-phosphate 1-dehydrogenase	483
641666163	284	40.57	1	280	5	281	3.0e-60	225	COG1737	DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains	281
641666164	87	32.14	1	84	13	93	1.0e-07	47.9	COG3113	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, MlaB component, contains STAS domain	99
641666165	204	32.84	1	197	2	202	4.0e-40	157	COG2854	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic MlaC component	202
641666166	269	40.49	3	239	5	250	9.0e-59	220	COG2853	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, lipoprotein component MlaA	250
641666168	259	46.27	5	259	12	265	6.0e-60	224	COG0767	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, permease component MlaE	267
641666169	278	59.69	11	267	4	261	2.0e-97	349	COG1127	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, ATPase component MlaF	263
641666170	491	42.26	23	488	2	455	0.0e+00	472	COG0493	NADPH-dependent glutamate synthase beta chain or related oxidoreductase	457
641666171	1588	56.62	725	1242	1	483	0.0e+00	662	COG0069	Glutamate synthase domain 2	485
641666172	237	20	1	140	1	136	3.0e-11	62.2	COG1943	REP element-mobilizing transposase RayT	136
641666173	307	55.89	5	298	4	299	1.0e-98	352	COG0031	Cysteine synthase	300
641666174	381	42.43	1	373	9	411	1.0e-92	333	COG0232	dGTP triphosphohydrolase	412
641666175	373	56.86	14	369	4	355	5.0e-129	454	COG0337	3-dehydroquinate synthetase	360
641666176	182	53.46	1	159	10	167	8.0e-50	190	COG0703	Shikimate kinase	172
641666178	726	33.97	61	719	51	709	9.0e-111	394	COG4796	Type II secretory pathway, component HofQ	709
641666179	186	37.72	14	179	6	169	2.0e-36	145	COG3168	Tfp pilus assembly protein PilP	170
641666180	238	41.55	15	221	1	200	2.0e-52	199	COG3167	Tfp pilus assembly protein PilO	211
641666181	212	34.5	1	200	4	200	6.0e-26	111	COG3166	Tfp pilus assembly protein PilN	206
641666182	352	40	1	350	5	353	1.0e-80	293	COG4972	Tfp pilus assembly protein, ATPase PilM	354
641666183	766	46.63	2	722	1	736	0.0e+00	834	COG5009	Membrane carboxypeptidase/penicillin-binding protein	797
641666184	128	40.19	15	121	1	105	3.0e-26	110	COG1965	Iron-binding protein CyaY, frataxin homolog	106
641666185	422	46.95	8	397	3	394	2.0e-120	425	COG0019	Diaminopimelate decarboxylase	394
641666187	417	20.28	5	417	3	354	2.0e-15	77.7	COG3203	Outer membrane protein (porin)	354
641666188	348	19.03	1	348	1	354	1.0e-18	87.7	COG3203	Outer membrane protein (porin)	354
641666189	216	42.58	8	216	1	204	8.0e-48	183	COG2941	Demethoxyubiquinone hydroxylase, CLK1/Coq7/Cat5 family	204
641666190	140	38.41	1	138	2	136	3.0e-28	117	COG1765	Uncharacterized OsmC-related protein	137
641666191	501	54.23	1	339	6	347	4.0e-121	428	COG1171	Threonine dehydratase	347
641666192	364	26.38	15	334	15	326	1.0e-24	107	COG2038	NaMN:DMB phosphoribosyltransferase	347
641666194	150	44.3	11	149	1	149	4.0e-20	90.9	COG2165	Type II secretory pathway, pseudopilin PulG	149
641666197	232	24.26	13	128	2	137	4.0e-08	51.9	COG4795	Type II secretory pathway, component PulJ	194
641666198	327	26.81	4	300	5	304	1.0e-30	127	COG3156	Type II secretory pathway, component PulK	323
641666199	428	19.28	20	399	12	364	7.0e-06	45.4	COG3297	Type II secretory pathway, component PulL	390
641666200	170	29.88	11	170	17	180	3.0e-09	55	COG3149	Type II secretory pathway, component PulM	181
641666202	753	29.55	13	694	2	578	2.0e-84	307	COG1450	Type II secretory pathway component GspD/PulD (secretin)	587
641666203	471	51.98	5	471	20	500	0.0e+00	549	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
641666204	405	42.89	1	401	1	393	8.0e-89	321	COG1459	Type II secretory pathway, component PulF	397
641666206	567	27.83	3	560	1	548	6.0e-68	252	COG2831	Hemolysin activation/secretion protein	554
641666208	251	25.59	31	238	2	212	5.0e-20	91.4	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
641666209	648	33.61	4	611	17	611	6.0e-120	425	COG1022	Long-chain acyl-CoA synthetase (AMP-forming)	613
641666210	264	42.46	11	262	2	250	2.0e-83	302	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
641666211	309	33.66	1	308	3	297	2.0e-37	149	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
641666212	354	33.44	22	340	1	308	2.0e-38	153	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
641666213	443	20.57	23	403	1	358	8.0e-16	78.6	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
641666214	270	49.59	5	248	1	237	1.0e-75	276	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
641666216	420	31.68	7	411	14	427	8.0e-58	218	COG1541	Phenylacetate-coenzyme A ligase PaaK, adenylate-forming domain family	438
641666217	324	40.37	1	323	1	319	9.0e-67	247	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
641666218	213	40.97	1	212	1	226	6.0e-48	183	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
641666219	464	27.22	122	442	9	327	4.0e-28	119	COG0642	Signal transduction histidine kinase	336
641666220	413	41.9	22	413	7	401	2.0e-115	409	COG0162	Tyrosyl-tRNA synthetase	401
641666221	464	28.78	166	439	3	277	6.0e-32	132	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
641666222	365	46.28	1	363	11	369	8.0e-90	324	COG2377	1,6-Anhydro-N-acetylmuramate kinase	371
641666223	121	55.05	12	120	1	109	2.0e-39	154	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
641666224	140	32.2	4	121	16	129	4.0e-19	87.3	COG1664	Cytoskeletal protein CcmA, bactofilin family	146
641666226	130	58.46	1	130	1	130	2.0e-45	174	COG0103	Ribosomal protein S9	130
641666227	142	62.24	1	142	1	143	5.0e-53	199	COG0102	Ribosomal protein L13	148
641666228	383	36.97	5	352	1	343	4.0e-71	261	COG1744	Basic membrane lipoprotein Med, periplasmic binding protein (PBP1-ABC) superfamily	345
641666230	306	45.25	1	305	4	303	3.0e-71	262	COG1079	ABC-type uncharacterized transport system, permease component	304
641666231	361	45.2	4	356	3	353	4.0e-74	272	COG4603	ABC-type uncharacterized transport system, permease component	356
641666232	519	50.7	5	497	3	501	0.0e+00	582	COG3845	ABC-type uncharacterized transport system, ATPase component	501
641666233	434	33.33	40	429	25	406	7.0e-68	251	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
641666234	325	23.47	10	317	1	296	9.0e-25	107	COG0583	DNA-binding transcriptional regulator, LysR family	297
641666235	530	48.12	7	510	9	483	0.0e+00	506	COG4630	Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A	493
641666236	787	60.51	11	787	4	780	0.0e+00	1091	COG4631	Xanthine dehydrogenase, molybdopterin-binding subunit B	781
641666237	278	30.77	7	274	4	255	9.0e-33	134	COG1975	Xanthine and CO dehydrogenase maturation factor, XdhC/CoxF family	278
641666240	1024	18.08	68	668	1	492	2.0e-35	144	COG0744	Membrane carboxypeptidase (penicillin-binding protein)	661
641666243	433	19.93	119	412	15	303	8.0e-07	48.8	COG0582	Integrase	309
641666251	631	28.92	94	618	32	548	1.0e-67	251	COG5519	Uncharcterized protein, DUF927 family	562
641666256	357	19.2	14	357	2	354	2.0e-15	77.3	COG3203	Outer membrane protein (porin)	354
641666257	573	36.91	159	514	31	408	2.0e-44	173	COG0840	Methyl-accepting chemotaxis protein	408
641666259	341	39.88	1	338	3	342	9.0e-82	297	COG1420	Transcriptional regulator of heat shock response	346
641666260	306	39.51	16	297	1	281	2.0e-66	246	COG0061	NAD kinase	281
641666261	567	43.85	1	554	1	556	0.0e+00	480	COG0497	DNA repair ATPase RecN	557
641666262	318	49.49	29	314	2	286	4.0e-90	324	COG1660	RNase adaptor protein for sRNA GlmZ degradation, contains a P-loop ATPase domain	286
641666263	209	31.94	11	197	12	200	5.0e-23	101	COG2802	Uncharacterized protein, similar to the N-terminal domain of Lon protease	221
641666264	384	43.24	11	380	10	337	2.0e-92	332	COG1194	Adenine-specific DNA glycosylase, acts on AG and A-oxoG pairs	342
641666266	276	46.24	1	275	1	273	1.0e-76	279	COG0266	Formamidopyrimidine-DNA glycosylase	273
641666267	620	28.3	400	610	32	239	7.0e-08	52.7	COG5010	Flp pilus assembly protein TadD, contains TPR repeats	257
641666268	198	26.28	22	158	5	155	1.0e-07	49.9	COG3017	Outer membrane lipoprotein LolB, involved in outer membrane biogenesis	206
641666269	291	42.47	6	287	4	288	3.0e-69	255	COG1947	4-diphosphocytidyl-2C-methyl-D-erythritol kinase	289
641666271	320	59.05	1	313	1	313	9.0e-122	429	COG0462	Phosphoribosylpyrophosphate synthetase	314
641666272	208	41.94	1	93	2	93	6.0e-20	91.1	COG1825	Ribosomal protein L25 (general stress protein Ctc)	93
641666273	213	52.91	1	189	1	189	2.0e-72	265	COG0193	Peptidyl-tRNA hydrolase	190
641666275	166	58.44	9	162	4	157	6.0e-58	216	COG0669	Phosphopantetheine adenylyltransferase	159
641666276	220	38.62	24	204	1	187	1.0e-36	146	COG0742	16S rRNA G966 N2-methylase RsmD	187
641666277	346	45.13	21	346	11	340	1.0e-94	339	COG0552	Signal recognition particle GTPase	340
641666278	831	32.69	1	260	9	267	2.0e-39	158	COG3267	Type II secretory pathway, component ExeA (predicted ATPase)	269
641666280	305	31.43	99	302	40	245	3.0e-22	99.4	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
641666281	517	18.24	11	458	17	458	7.0e-28	119	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
641666282	213	30.29	10	211	5	206	1.0e-23	103	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
641666283	469	47.49	251	469	20	226	7.0e-65	241	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
641666285	243	51.26	8	242	1	237	7.0e-75	273	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
641666286	135	56.03	9	124	5	120	2.0e-42	164	COG3536	Uncharacterized conserved protein, DUF971 family	120
641666287	247	67.39	1	230	1	230	2.0e-104	371	COG0588	Phosphoglycerate mutase (BPG-dependent)	230
641666288	140	36.73	43	138	11	108	9.0e-16	76.1	COG0607	Rhodanese-related sulfurtransferase	110
641666289	80	52	1	74	5	79	2.0e-19	86.9	COG0695	Glutaredoxin	80
641666290	628	54.71	14	628	15	627	0.0e+00	748	COG3158	K+ transporter	627
641666292	930	38.22	24	930	55	956	0.0e+00	638	COG1391	Glutamine synthetase adenylyltransferase	963
641666293	1450	23.68	29	1432	10	1271	1.0e-118	422	COG3164	Uncharacterized conserved protein YhdP, contains DUF3971 and AsmA2 domains	1271
641666294	272	39.13	1	271	3	263	1.0e-54	206	COG0388	Predicted amidohydrolase	274
641666295	418	33.41	17	414	1	383	4.0e-40	159	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
641666296	705	39.21	15	705	4	730	0.0e+00	583	COG1198	Primosomal protein N' (replication factor Y) - superfamily II helicase	730
641666297	356	50.99	1	351	1	351	3.0e-120	425	COG0407	Uroporphyrinogen-III decarboxylase	352
641666298	125	47.93	1	121	14	134	4.0e-29	119	COG0355	FoF1-type ATP synthase, epsilon subunit	135
641666299	474	72.88	9	473	1	465	0.0e+00	805	COG0055	FoF1-type ATP synthase, beta subunit	468
641666300	293	50	5	292	1	286	1.0e-93	336	COG0224	FoF1-type ATP synthase, gamma subunit	287
641666301	512	66.21	1	512	1	501	0.0e+00	799	COG0056	FoF1-type ATP synthase, alpha subunit	504
641666302	177	37.85	1	175	1	177	9.0e-36	143	COG0712	FoF1-type ATP synthase, delta subunit	178
641666303	156	37.66	3	156	5	158	2.0e-16	78.8	COG0711	FoF1-type ATP synthase, membrane subunit b or b'	161
641666304	82	43.84	6	78	7	79	1.0e-06	44.8	COG0636	FoF1-type ATP synthase, membrane subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K	79
641666305	298	34.83	9	298	4	246	6.0e-45	174	COG0356	FoF1-type ATP synthase, membrane subunit a	246
641666307	299	38.28	1	294	12	304	1.0e-61	229	COG3386	Sugar lactone lactonase YvrE	307
641666309	219	37.36	2	181	6	183	3.0e-27	115	COG3658	Cytochrome b	192
641666310	150	37.06	6	148	4	144	3.0e-19	88.2	COG3909	Cytochrome c556	147
641666311	283	38.78	4	283	3	291	2.0e-62	232	COG0384	Predicted epimerase YddE/YHI9, PhzF superfamily	291
641666312	407	44.1	15	400	70	458	8.0e-94	337	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
641666313	308	28.72	22	299	4	284	1.0e-07	50.6	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
641666314	198	28.92	1	196	1	204	5.0e-13	68	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
641666315	313	37.02	26	313	65	335	1.0e-60	227	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
641666316	1603	34.24	791	1084	58	336	7.0e-40	160	COG0642	Signal transduction histidine kinase	336
641666317	322	39.3	11	315	124	431	1.0e-69	256	COG3706	Two-component response regulator, PleD family, consists of two REC domains and a diguanylate cyclase (GGDEF) domain	435
641666321	320	41.03	16	304	1	289	4.0e-70	258	COG0053	Divalent metal cation (Fe/Co/Zn/Cd) transporter	304
641666322	120	44.14	10	120	1	103	2.0e-18	84.5	COG0023	Translation initiation factor 1 (eIF-1/SUI1)	104
641666323	278	29.41	155	254	26	127	2.0e-11	63	COG0526	Thiol-disulfide isomerase or thioredoxin	127
641666325	203	34.55	14	202	6	168	2.0e-25	109	COG0723	Rieske Fe-S protein	177
641666326	441	36.44	7	438	118	558	2.0e-89	323	COG3829	Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding Fis domains	560
641666327	133	41.27	4	125	1	126	4.0e-16	77.2	COG3094	Uncharacterized membrane protein SirB2	129
641666329	190	31.18	18	187	7	162	1.0e-22	99.8	COG3495	Uncharacterized protein	166
641666330	425	19.68	3	422	7	406	1.0e-13	71.8	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
641666331	243	37.98	22	229	15	215	3.0e-50	191	COG1136	ABC-type lipoprotein export system, ATPase component	226
641666333	307	33.22	6	300	3	302	3.0e-59	222	COG0803	ABC-type Zn uptake system ZnuABC, Zn-binding component ZnuA	303
641666334	295	39.78	7	279	4	273	1.0e-32	133	COG1108	ABC-type Mn2+/Zn2+ transport system, permease component	274
641666335	244	41.07	7	222	4	226	3.0e-65	242	COG1121	ABC-type Mn2+/Zn2+ transport system, ATPase component	254
641666337	137	34.96	9	128	17	139	8.0e-23	99.2	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
641666339	131	45.65	1	92	2	93	2.0e-18	84.8	COG0776	Bacterial nucleoid DNA-binding protein	94
641666341	682	25.35	10	506	5	472	1.0e-56	215	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
641666341	682	39.35	531	682	11	158	2.0e-27	117	COG2030	Acyl dehydratase	159
641666342	362	24.73	273	360	5	97	8.0e-11	61.6	COG0633	Ferredoxin	102
641666342	362	31.3	6	266	5	250	2.0e-45	176	COG1018	Ferredoxin-NADP reductase	266
641666344	183	30.63	3	111	2	111	7.0e-18	83.8	COG2151	Metal-sulfur cluster biosynthetic enzyme	111
641666345	263	38.49	15	263	23	265	1.0e-49	190	COG3396	1,2-phenylacetyl-CoA epoxidase, catalytic subunit	265
641666346	100	52.48	10	100	9	109	3.0e-27	113	COG3460	1,2-phenylacetyl-CoA epoxidase, PaaB subunit	117
641666347	342	45.15	37	303	1	265	3.0e-88	318	COG3396	1,2-phenylacetyl-CoA epoxidase, catalytic subunit	265
641666348	335	33.53	1	331	1	342	1.0e-55	210	COG1744	Basic membrane lipoprotein Med, periplasmic binding protein (PBP1-ABC) superfamily	345
641666349	550	48.13	32	536	1	501	0.0e+00	558	COG3845	ABC-type uncharacterized transport system, ATPase component	501
641666350	360	38.55	1	357	1	354	4.0e-61	228	COG4603	ABC-type uncharacterized transport system, permease component	356
641666351	307	43.62	11	306	8	304	9.0e-63	233	COG1079	ABC-type uncharacterized transport system, permease component	304
641666353	264	31.87	1	247	2	239	5.0e-52	197	COG1058	Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA	255
641666354	471	49.26	4	469	2	441	0.0e+00	523	COG0174	Glutamine synthetase	443
641666356	357	47.73	8	356	9	354	1.0e-95	343	COG3852	Signal transduction histidine kinase, nitrogen specific	363
641666357	494	44.98	1	494	4	457	0.0e+00	505	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
641666358	215	29.56	5	203	10	212	1.0e-19	89.9	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
641666359	295	37.65	54	295	1	236	1.0e-48	187	COG0412	Dienelactone hydrolase	236
641666361	234	36.96	5	229	3	227	2.0e-44	172	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
641666362	652	29.53	276	523	100	336	2.0e-31	131	COG0642	Signal transduction histidine kinase	336
641666363	547	36.14	21	540	11	525	2.0e-111	396	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
641666364	250	46.99	4	248	2	250	2.0e-77	282	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
641666365	239	49.37	8	239	1	237	1.0e-77	283	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
641666366	403	23.04	19	377	2	366	2.0e-37	149	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
641666367	294	41.24	11	294	6	294	3.0e-46	179	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
641666368	311	39.6	11	307	14	314	1.0e-41	163	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
641666369	593	32.08	34	455	5	392	6.0e-63	235	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
641666370	158	37.24	1	137	9	153	3.0e-21	94.4	COG2030	Acyl dehydratase	159
641666371	249	48.85	1	249	1	260	8.0e-70	257	COG2086	Electron transfer flavoprotein, alpha and beta subunits	260
641666372	308	53.97	1	308	1	310	1.0e-80	293	COG2025	Electron transfer flavoprotein, alpha subunit	313
641666373	514	37.22	25	505	4	492	6.0e-98	351	COG0248	Exopolyphosphatase/pppGpp-phosphohydrolase	492
641666374	686	48.19	5	682	2	682	0.0e+00	752	COG0855	Polyphosphate kinase	696
641666375	195	20.14	44	187	1	129	8.0e-10	57.2	COG1246	N-acetylglutamate synthase or related acetyltransferase, GNAT family	153
641666376	395	20.34	12	343	10	321	3.0e-14	73.4	COG0707	UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase	357
641666377	290	24.53	24	280	7	236	8.0e-27	114	COG0688	Phosphatidylserine decarboxylase	239
641666378	549	27.55	131	522	38	432	1.0e-54	207	COG0001	Glutamate-1-semialdehyde aminotransferase	432
641666380	413	25.13	22	396	2	380	2.0e-37	150	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
641666382	582	30.53	5	564	3	502	8.0e-89	321	COG3540	Phosphodiesterase/alkaline phosphatase D	522
641666383	498	27.88	1	425	2	416	9.0e-34	138	COG3025	Inorganic triphosphatase YgiF, contains CYTH and CHAD domains	432
641666384	628	33.6	246	626	9	379	3.0e-55	209	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
641666385	339	24.62	1	326	1	326	8.0e-36	144	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
641666387	76	35.53	1	75	2	76	4.0e-17	79.9	COG0425	TusA-related sulfurtransferase	78
641666389	526	37.37	36	517	4	492	3.0e-94	339	COG0248	Exopolyphosphatase/pppGpp-phosphohydrolase	492
641666391	362	26.94	64	359	24	320	4.0e-49	189	COG0598	Mg2+ and Co2+ transporter CorA	322
641666392	310	41.08	51	288	1	237	2.0e-66	246	COG2908	UDP-2,3-diacylglucosamine pyrophosphatase LpxH	237
641666395	398	27.36	46	340	5	291	5.0e-25	109	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
641666396	603	31.13	5	481	1	455	6.0e-34	139	COG1807	4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferase of PMT family	535
641666399	288	57.49	1	286	2	287	2.0e-116	411	COG1210	UTP-glucose-1-phosphate uridylyltransferase	291
641666400	342	30.28	1	307	4	318	5.0e-36	145	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
641666401	953	49.37	5	953	1	876	0.0e+00	1151	COG0525	Valyl-tRNA synthetase	877
641666402	282	52.65	1	282	1	283	3.0e-91	328	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
641666403	336	28.52	11	298	7	292	2.0e-34	139	COG1597	Diacylglycerol kinase family enzyme	301
641666404	306	34.75	1	303	1	297	3.0e-29	122	COG0583	DNA-binding transcriptional regulator, LysR family	297
641666405	342	21.58	47	333	47	291	2.0e-15	76.6	COG2159	Predicted metal-dependent hydrolase, TIM-barrel fold	293
641666406	231	42.51	17	223	5	210	4.0e-47	181	COG0684	Regulator of RNase E activity RraA	210
641666407	313	21.82	8	220	2	214	1.0e-22	100	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
641666408	314	24.74	25	309	1	276	4.0e-31	128	COG3618	Predicted metal-dependent hydrolase, TIM-barrel fold	279
641666411	318	26.77	2	309	1	325	2.0e-37	150	COG0673	Predicted dehydrogenase	342
641666412	316	31.51	1	309	2	308	3.0e-28	119	COG0679	Predicted permease	311
641666413	441	38.99	2	434	6	429	4.0e-102	365	COG1253	Hemolysin or related protein, contains CBS domains	429
641666414	473	42.45	15	461	2	449	8.0e-128	450	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
641666415	408	43.84	1	402	2	386	9.0e-97	347	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
641666416	236	42.54	4	231	3	223	1.0e-55	210	COG0132	Dethiobiotin synthetase	223
641666417	345	60.77	27	335	13	321	1.0e-120	426	COG0502	Biotin synthase or related enzyme	335
641666418	429	32.61	13	422	22	407	7.0e-68	251	COG2124	Cytochrome P450	411
641666419	104	45.19	1	104	2	105	3.0e-19	86.7	COG2076	Multidrug transporter EmrE and related cation transporters	106
641666420	333	37.06	1	332	1	326	2.0e-64	239	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
641666421	204	19.6	1	196	3	201	1.0e-05	43.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
641666422	237	48.09	6	237	3	237	4.0e-69	254	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
641666423	282	45.78	37	281	2	250	3.0e-71	262	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
641666424	335	38.41	7	319	8	314	3.0e-39	155	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
641666425	293	37.67	1	290	1	290	4.0e-44	172	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
641666426	390	32	25	369	5	354	2.0e-43	169	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
641666427	272	24.26	32	265	22	281	6.0e-14	71.7	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
641666428	531	31.76	14	531	4	524	3.0e-104	372	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
641666429	519	24.71	6	511	2	472	1.0e-51	197	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
641666431	318	31.61	143	316	1	172	1.0e-29	124	COG0703	Shikimate kinase	172
641666432	555	34.6	50	260	25	222	9.0e-19	89	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
641666433	475	24.42	102	318	11	202	8.0e-14	72.3	COG3396	1,2-phenylacetyl-CoA epoxidase, catalytic subunit	265
641666435	267	36.22	11	262	7	256	3.0e-41	162	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
641666436	505	45.68	3	279	8	285	2.0e-81	296	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
641666437	151	36.81	1	141	15	154	7.0e-25	106	COG2030	Acyl dehydratase	159
641666438	400	42.48	1	400	1	392	7.0e-83	301	COG0183	Acetyl-CoA acetyltransferase	392
641666442	400	26.84	8	391	2	387	3.0e-47	182	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
641666443	351	37.76	14	347	10	343	9.0e-70	257	COG3435	Gentisate 1,2-dioxygenase	351
641666444	235	36.62	25	235	57	266	2.0e-47	182	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
641666445	212	35.81	1	212	1	209	2.0e-29	122	COG0625	Glutathione S-transferase	211
641666446	178	22.78	20	177	4	159	6.0e-07	47.6	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
641666447	443	34.03	59	442	5	379	3.0e-69	256	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
641666448	344	24.93	1	341	2	332	2.0e-35	143	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
641666450	274	53.69	2	245	27	270	1.0e-83	303	COG2326	Polyphosphate kinase 2, PPK2 family	270
641666451	575	40.72	4	564	16	592	0.0e+00	489	COG4178	ABC-type uncharacterized transport system, permease and ATPase components	604
641666453	186	42.02	1	185	3	189	1.0e-34	139	COG0406	Broad specificity phosphatase PhoE	208
641666456	583	17.57	21	555	7	526	3.0e-27	117	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
641666457	254	31.4	13	252	2	242	8.0e-42	163	COG1414	DNA-binding transcriptional regulator, IclR family	246
641666458	297	29.96	3	263	2	267	3.0e-43	168	COG0169	Shikimate 5-dehydrogenase	283
641666459	383	32.8	19	376	1	365	7.0e-44	171	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
641666460	291	37.63	1	290	3	297	9.0e-43	167	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
641666461	330	40.13	1	307	2	314	1.0e-46	180	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
641666462	252	41.53	7	251	2	249	3.0e-75	275	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
641666463	249	48.09	6	238	4	237	5.0e-71	261	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
641666464	295	38.95	11	265	10	272	4.0e-47	182	COG3185	4-hydroxyphenylpyruvate dioxygenase and related hemolysins	363
641666465	305	22.48	17	264	5	255	2.0e-18	86.8	COG1082	Sugar phosphate isomerase/epimerase	274
641666467	419	54.55	6	225	1	206	3.0e-58	219	COG2715	Spore maturation protein SpmA (function unknown)	206
641666468	332	38.99	6	316	2	315	5.0e-74	271	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
641666470	307	29.05	9	300	1	296	3.0e-24	106	COG0583	DNA-binding transcriptional regulator, LysR family	297
641666473	358	18.29	26	353	10	305	1.0e-09	57.7	COG3021	Uncharacterized conserved protein YafD, endonuclease/exonuclease/phosphatase (EEP) superfamily	309
641666474	495	22.56	211	473	1	233	1.0e-40	161	COG0775	Nucleoside phosphorylase	234
641666476	1021	37.04	209	504	54	336	2.0e-40	162	COG0642	Signal transduction histidine kinase	336
641666477	301	17.55	13	254	26	260	3.0e-06	45.8	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
641666479	498	34	50	498	3	450	7.0e-48	185	COG1538	Outer membrane protein TolC	457
641666480	437	24.4	28	404	8	368	5.0e-19	89.4	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
641666481	254	50.44	7	231	1	226	1.0e-81	296	COG1136	ABC-type lipoprotein export system, ATPase component	226
641666482	403	31.58	18	403	2	419	2.0e-34	140	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
641666483	312	21.99	13	243	2	215	1.0e-07	51.1	COG1462	Curli biogenesis system outer membrane secretion channel CsgG	252
641666484	195	26.09	81	194	9	110	8.0e-08	50.7	COG0607	Rhodanese-related sulfurtransferase	110
641666485	478	38.77	12	478	1	444	1.0e-44	174	COG1538	Outer membrane protein TolC	457
641666486	1058	55.24	3	1027	3	1009	0.0e+00	1037	COG0841	Multidrug efflux pump subunit AcrB	1009
641666487	408	36.27	15	396	4	372	6.0e-32	132	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
641666488	208	24.1	1	194	2	196	8.0e-07	47.3	COG1309	DNA-binding transcriptional regulator, AcrR family	201
641666489	103	28.41	1	87	18	105	5.0e-14	69.2	COG3339	Uncharacterized membrane protein YkvA, DUF1232 family	116
641666490	148	30.46	1	144	5	149	9.0e-19	86.3	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
641666492	700	35.85	25	697	10	694	0.0e+00	547	COG0480	Translation elongation factor EF-G, a GTPase	697
641666494	367	34.23	13	336	12	341	2.0e-66	246	COG1744	Basic membrane lipoprotein Med, periplasmic binding protein (PBP1-ABC) superfamily	345
641666496	303	31.1	40	287	16	264	1.0e-53	203	COG1526	Formate dehydrogenase assembly factor FdhD	266
641666498	384	31.16	149	361	1	210	1.0e-46	180	COG2864	Cytochrome b subunit of formate dehydrogenase	218
641666500	214	45.93	1	164	8	157	1.0e-37	149	COG0437	Fe-S-cluster-containing dehydrogenase component	203
641666505	743	30	598	674	20	99	3.0e-07	51.1	COG1145	Ferredoxin	99
641666506	214	25.51	22	211	7	198	4.0e-20	91.6	COG3381	Cytoplasmic chaperone TorD involved in molybdoenzyme TorA maturation	204
641666507	199	38.97	7	198	5	192	1.0e-36	146	COG0746	Molybdopterin-guanine dinucleotide biosynthesis protein A	192
641666508	459	45.39	16	456	2	454	2.0e-113	402	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
641666510	496	22.54	18	469	1	443	2.0e-12	67.5	COG1538	Outer membrane protein TolC	457
641666512	4231	33.55	1157	1466	68	366	1.0e-38	157	COG5276	Uncharacterized conserved protein	370
641666515	356	46.31	25	355	7	343	3.0e-91	329	COG1816	Adenosine deaminase	345
641666516	374	29.65	20	355	23	354	8.0e-13	68.2	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
641666517	1100	28.49	20	1087	1	1009	0.0e+00	599	COG0841	Multidrug efflux pump subunit AcrB	1009
641666520	148	22.96	5	139	1	133	8.0e-12	63.1	COG1765	Uncharacterized OsmC-related protein	137
641666521	118	33.33	11	105	12	107	3.0e-09	54	COG0640	DNA-binding transcriptional regulator, ArsR family	110
641666523	249	25.98	1	204	1	189	1.0e-19	90.5	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
641666524	345	45.76	1	329	1	286	6.0e-95	340	COG0191	Fructose/tagatose bisphosphate aldolase	286
641666525	237	38.29	1	222	2	217	1.0e-36	146	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
641666526	675	56.5	3	665	1	663	0.0e+00	943	COG0021	Transketolase	663
641666527	294	60.21	1	289	1	288	6.0e-123	434	COG3954	Phosphoribulokinase	289
641666528	365	50.29	6	347	1	325	5.0e-121	427	COG0158	Fructose-1,6-bisphosphatase	326
641666529	225	55.56	1	225	2	219	1.0e-82	299	COG0036	Pentose-5-phosphate-3-epimerase	220
641666530	316	37.54	5	302	2	297	4.0e-38	152	COG0583	DNA-binding transcriptional regulator, LysR family	297
641666532	420	33.17	8	411	1	408	1.0e-75	277	COG2733	Uncharacterized membrane-anchored protein YjiN, DUF445 family	415
641666535	650	55.11	25	650	5	627	0.0e+00	746	COG3158	K+ transporter	627
641666536	243	41.42	4	239	2	229	7.0e-50	190	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
641666539	268	22.22	1	267	11	293	1.0e-25	110	COG0714	MoxR-like ATPase	329
641666540	460	34.19	24	440	22	423	5.0e-60	225	COG1850	Ribulose 1,5-bisphosphate carboxylase, large subunit, or a RuBisCO-like protein	429
641666541	289	38.58	50	289	49	314	2.0e-46	179	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
641666543	312	25.53	53	280	30	252	2.0e-16	79.9	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
641666544	125	31.31	27	125	5	101	5.0e-11	60	COG2863	Cytochrome c553	121
641666545	433	21.64	42	428	1	371	5.0e-22	99.2	COG0446	NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase	415
641666546	143	40	29	143	5	112	5.0e-20	90.3	COG1416	Intracellular sulfur oxidation protein, DsrE/DsrF family	112
641666550	60	40.98	1	60	17	77	3.0e-11	59.9	COG0425	TusA-related sulfurtransferase	78
641666551	580	26.3	30	531	11	467	3.0e-61	229	COG0737	2',3'-cyclic-nucleotide 2'-phosphodiesterase/5'- or 3'-nucleotidase, 5'-nucleotidase family	517
641666555	152	36.49	10	152	5	148	2.0e-18	85.1	COG5501	Predicted secreted protein	148
641666556	355	40.82	257	353	9	106	2.0e-13	70.5	COG4654	Cytochrome c551/c552	110
641666557	457	28.21	35	307	4	230	2.0e-24	107	COG2041	Periplasmic DMSO/TMAO reductase YedYZ, molybdopterin-dependent catalytic subunit	271
641666558	274	34.56	9	272	8	256	1.0e-21	96.7	COG5662	Transmembrane transcriptional regulator (anti-sigma factor RsiW)	256
641666559	180	37.95	8	169	23	177	3.0e-20	91.7	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
641666560	129	50	12	129	23	138	1.0e-31	128	COG4315	Predicted lipoprotein with conserved Yx(FWY)xxD motif (function unknown)	138
641666561	338	25.73	1	333	1	329	4.0e-20	92.6	COG1275	Tellurite resistance protein TehA and related permeases	329
641666564	217	24.54	12	217	2	207	2.0e-22	99.3	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
641666566	260	36.67	50	258	1	205	2.0e-42	166	COG0545	FKBP-type peptidyl-prolyl cis-trans isomerase	205
641666570	110	40.86	6	93	9	101	3.0e-12	63.9	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
641666571	732	37.5	1	712	4	708	0.0e+00	555	COG0643	Chemotaxis protein histidine kinase CheA	716
641666572	772	37.42	433	719	83	408	2.0e-38	155	COG0840	Methyl-accepting chemotaxis protein	408
641666573	176	34.62	12	167	16	165	4.0e-32	131	COG0835	Chemotaxis signal transduction protein	165
641666574	350	47.67	3	345	1	339	4.0e-90	324	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
641666576	159	31.21	3	136	10	150	8.0e-07	46.6	COG2391	Uncharacterized membrane protein YedE/YeeE, contains two sulfur transport domains	198
641666577	337	73.09	10	336	20	346	0.0e+00	529	COG1613	ABC-type sulfate transport system, periplasmic component	348
641666578	277	58.46	8	276	3	274	3.0e-70	258	COG0555	ABC-type sulfate transport system, permease component	274
641666579	337	69.86	35	316	4	285	1.0e-117	416	COG4208	ABC-type sulfate transport system, permease component	287
641666580	355	54.34	1	342	1	345	1.0e-111	397	COG1118	ABC-type sulfate/molybdate transport systems, ATPase component	345
641666582	532	36.67	6	532	13	539	5.0e-118	418	COG0405	Gamma-glutamyltranspeptidase	539
641666583	312	31.13	1	300	1	295	3.0e-33	135	COG0583	DNA-binding transcriptional regulator, LysR family	297
641666585	224	36.06	1	206	2	208	4.0e-35	141	COG0406	Broad specificity phosphatase PhoE	208
641666586	153	46.58	5	150	4	149	7.0e-43	166	COG1952	Preprotein translocase subunit SecB	157
641666587	337	50.15	1	336	2	329	4.0e-98	351	COG0240	Glycerol-3-phosphate dehydrogenase	329
641666588	156	52.56	1	156	2	155	7.0e-57	213	COG0219	tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain	155
641666589	266	35.22	36	264	5	224	3.0e-37	149	COG1040	Predicted amidophosphoribosyltransferases	225
641666591	388	27.73	271	388	29	145	8.0e-10	58.4	COG2010	Cytochrome c, mono- and diheme variants	150
641666591	388	31.15	45	285	23	236	5.0e-50	192	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
641666592	544	56.29	22	533	1	515	0.0e+00	558	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
641666594	214	38.69	14	205	1	189	4.0e-48	184	COG3175	Cytochrome c oxidase assembly protein Cox11	195
641666596	293	34.17	54	293	1	206	3.0e-37	148	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
641666598	251	29.71	9	246	10	247	3.0e-28	118	COG3346	Cytochrome oxidase assembly protein ShyY1	252
641666600	411	26.84	42	393	21	320	2.0e-29	123	COG1612	Heme A synthase	323
641666601	305	48.24	15	298	18	298	5.0e-82	297	COG0109	Polyprenyltransferase (heme O synthase)	304
641666602	211	40.4	15	210	13	207	2.0e-40	158	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
641666603	632	46.24	1	519	1	526	0.0e+00	509	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
641666604	182	29.55	7	182	14	188	4.0e-25	108	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
641666605	552	33.84	30	546	18	514	8.0e-65	241	COG0815	Apolipoprotein N-acyltransferase	518
641666606	306	41.52	28	301	11	286	5.0e-73	267	COG4535	Mg2+ and Co2+ transporter CorC, contains CBS pair and CorC-HlyC domains	293
641666607	343	43.7	6	343	1	322	3.0e-89	322	COG0523	GTPase, G3E family	323
641666608	162	56.67	43	162	1	120	5.0e-28	117	COG1734	RNA polymerase-binding transcription factor DksA	120
641666610	178	64.77	3	178	1	176	3.0e-72	264	COG5405	ATP-dependent protease HslVU (ClpYQ), peptidase subunit	178
641666611	451	63.27	1	451	2	444	0.0e+00	642	COG1220	ATP-dependent protease HslVU (ClpYQ), ATPase subunit	444
641666612	262	27.69	3	253	2	248	6.0e-35	141	COG1521	Pantothenate kinase type III	251
641666614	278	49.43	11	273	2	248	1.0e-83	303	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
641666615	331	37.21	74	328	2	250	1.0e-46	180	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
641666616	417	25.94	15	357	1	334	3.0e-46	179	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
641666617	1096	30.09	173	488	17	310	2.0e-63	238	COG1703	Putative periplasmic protein kinase ArgK or related GTPase of G3E family	323
641666617	1096	36.17	6	145	1	137	5.0e-29	123	COG2185	Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding)	143
641666617	1096	37.28	531	1096	5	548	0.0e+00	532	COG1884	Methylmalonyl-CoA mutase, N-terminal domain/subunit	548
641666618	320	20.76	79	314	20	235	2.0e-11	63.7	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
641666620	565	39.32	5	560	1	484	0.0e+00	482	COG2509	Uncharacterized FAD-dependent dehydrogenase	486
641666623	224	39.34	18	223	2	209	3.0e-43	168	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
641666624	334	28.86	42	332	8	302	8.0e-26	111	COG3391	DNA-binding beta-propeller fold protein YncE	381
641666626	583	60.92	14	424	1	408	3.0e-122	432	COG4651	Predicted Kef-type K+ transport protein, K+/H+ antiporter domain	408
641666627	395	36.72	4	395	2	392	1.0e-77	283	COG0183	Acetyl-CoA acetyltransferase	392
641666629	100	17.71	1	94	2	96	5.0e-06	42.6	COG2329	Heme-degrading monooxygenase HmoA and related ABM domain proteins	105
641666630	184	47.22	1	180	1	180	8.0e-54	203	COG4681	Uncharacterized conserved protein YaeQ, suppresses RfaH defect	181
641666631	547	58.33	10	536	2	528	0.0e+00	765	COG4108	Peptide chain release factor RF-3	528
641666632	390	39.15	7	384	1	356	2.0e-102	366	COG1304	FMN-dependent dehydrogenase, includes L-lactate dehydrogenase and type II isopentenyl diphosphate isomerase	360
641666633	306	30.77	10	297	1	297	1.0e-22	100	COG0583	DNA-binding transcriptional regulator, LysR family	297
641666634	125	75.61	1	123	7	129	4.0e-49	186	COG0048	Ribosomal protein S12	129
641666635	156	60.14	2	149	1	148	2.0e-51	194	COG0049	Ribosomal protein S7	148
641666636	700	67.28	1	700	1	693	0.0e+00	1012	COG0480	Translation elongation factor EF-G, a GTPase	697
641666637	396	83.84	1	396	1	394	0.0e+00	714	COG0050	Translation elongation factor EF-Tu, a GTPase	394
641666638	103	75.73	1	103	1	103	5.0e-39	152	COG0051	Ribosomal protein S10	104
641666640	1407	50.06	14	853	2	808	0.0e+00	882	COG0086	DNA-directed RNA polymerase, beta' subunit/160 kD subunit	808
641666642	124	63.71	1	124	1	124	8.0e-26	109	COG0222	Ribosomal protein L7/L12	124
641666643	182	40	1	173	1	175	1.0e-29	123	COG0244	Ribosomal protein L10	175
641666644	237	57.89	1	227	1	228	2.0e-74	272	COG0081	Ribosomal protein L1	228
641666645	143	67.61	2	143	1	141	6.0e-50	189	COG0080	Ribosomal protein L11	141
641666646	188	52.54	12	188	1	177	2.0e-51	195	COG0250	Transcription antitermination factor NusG	178
641666647	127	35.71	49	118	2	71	5.0e-09	53.5	COG0690	Preprotein translocase subunit SecE	73
641666649	396	83.84	1	396	1	394	0.0e+00	714	COG0050	Translation elongation factor EF-Tu, a GTPase	394
641666653	248	44.69	26	248	2	222	4.0e-63	235	COG0692	Uracil DNA glycosylase	223
641666654	262	54.65	5	262	1	254	2.0e-80	292	COG0134	Indole-3-glycerol phosphate synthase	254
641666655	345	52.1	7	340	6	338	2.0e-110	392	COG0547	Anthranilate phosphoribosyltransferase	338
641666656	188	64.17	1	186	3	189	1.0e-78	285	COG0512	Anthranilate/para-aminobenzoate synthase component II	191
641666657	397	38.19	1	397	1	397	8.0e-82	297	COG1459	Type II secretory pathway, component PulF	397
641666658	567	44.98	71	564	14	498	0.0e+00	496	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
641666662	760	24.49	5	724	5	690	1.0e-42	168	COG4796	Type II secretory pathway, component HofQ	709
641666663	161	28.12	4	161	3	149	8.0e-12	63.5	COG2165	Type II secretory pathway, pseudopilin PulG	149
641666665	264	23.61	18	159	7	147	2.0e-08	53.1	COG2165	Type II secretory pathway, pseudopilin PulG	149
641666667	541	27.08	163	531	4	358	6.0e-27	115	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
641666668	228	24.32	9	221	5	207	2.0e-20	92.8	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
641666669	222	27.1	11	215	4	207	1.0e-27	117	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
641666670	660	23.1	187	505	13	349	7.0e-18	86	COG3391	DNA-binding beta-propeller fold protein YncE	381
641666672	442	20.06	103	436	3	331	2.0e-21	97.5	COG0642	Signal transduction histidine kinase	336
641666673	182	49.71	7	181	8	182	3.0e-53	200	COG4567	Two-component response regulator, ActR/RegA family, consists of REC and Fis-type HTH domains	182
641666674	495	39.29	5	495	14	514	2.0e-122	432	COG1640	4-alpha-glucanotransferase	520
641666675	495	46.99	19	495	1	461	0.0e+00	481	COG0147	Anthranilate/para-aminobenzoate synthases component I	462
641666676	221	37.26	9	218	5	214	9.0e-42	163	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
641666677	228	56.7	5	228	3	219	1.0e-82	299	COG0036	Pentose-5-phosphate-3-epimerase	220
641666678	128	46.4	4	128	2	126	2.0e-41	161	COG2967	Uncharacterized protein affecting Mg2+/Co2+ transport	126
641666679	694	26.18	1	689	5	672	8.0e-121	428	COG4389	Site-specific recombinase	677
641666680	431	33.7	81	431	18	366	4.0e-68	252	COG2821	Membrane-bound lytic murein transglycosylase	373
641666682	186	40.67	30	179	6	154	1.0e-31	129	COG1522	DNA-binding transcriptional regulator, Lrp family	154
641666683	1185	31.68	27	726	2	636	0.0e+00	577	COG4231	TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit	640
641666684	89	62.67	1	75	1	75	1.0e-22	97.9	COG0361	Translation initiation factor IF-1	75
641666687	315	39.45	1	315	1	316	4.0e-63	235	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
641666688	393	42.41	39	383	8	342	4.0e-74	272	COG3178	Predicted phosphotransferase, aminoglycoside/choline kinase (APH/ChoK) family	351
641666689	863	25.23	106	836	51	780	8.0e-90	325	COG1452	LPS assembly outer membrane protein LptD (organic solvent tolerance protein OstA)	784
641666691	269	47.47	5	253	4	256	6.0e-80	290	COG0030	16S rRNA A1518 and A1519 N6-dimethyltransferase RsmA/KsgA/DIM1 (may also have DNA glycosylase/AP lyase activity)	259
641666693	137	46.62	4	135	19	150	5.0e-33	133	COG4290	Guanyl-specific ribonuclease Sa	152
641666694	772	40.9	439	772	5	327	3.0e-92	333	COG0280	Phosphotransacetylase	327
641666694	772	55.1	1	438	7	432	0.0e+00	565	COG0281	Malic enzyme	432
641666696	215	47.55	11	214	6	202	2.0e-46	178	COG4566	Two-component response regulator, FixJ family, consists of REC and HTH domains	202
641666697	331	44.41	1	326	1	317	2.0e-77	282	COG0611	Thiamine monophosphate kinase	317
641666698	185	35.93	14	177	2	160	4.0e-23	101	COG1267	Phosphatidylglycerophosphatase A	160
641666699	169	52.63	17	168	11	162	2.0e-46	178	COG1546	Nicotinamide mononucleotide (NMN) deamidase PncC	162
641666700	132	70.69	1	116	1	116	2.0e-43	167	COG0203	Ribosomal protein L17	116
641666701	328	54.4	5	322	1	313	5.0e-98	351	COG0202	DNA-directed RNA polymerase, alpha subunit/40 kD subunit	317
641666702	207	59.62	1	207	1	205	6.0e-59	220	COG0522	Ribosomal protein S4 or related protein	205
641666703	134	70.73	12	134	7	129	6.0e-45	173	COG0100	Ribosomal protein S11	129
641666704	121	57.02	1	120	1	121	7.0e-39	152	COG0099	Ribosomal protein S13	121
641666706	72	65.28	1	72	1	72	3.0e-25	106	COG0361	Translation initiation factor IF-1	75
641666707	436	52.68	8	429	10	432	6.0e-124	437	COG0201	Preprotein translocase subunit SecY	436
641666708	144	53.06	1	141	1	147	6.0e-28	116	COG0200	Ribosomal protein L15	152
641666709	60	56.6	7	59	1	53	5.0e-12	62.8	COG1841	Ribosomal protein L30/L7E	55
641666710	172	56.71	10	172	17	180	1.0e-53	202	COG0098	Ribosomal protein S5	181
641666711	121	49.18	1	121	5	125	2.0e-25	107	COG0256	Ribosomal protein L18	125
641666712	177	52.54	1	176	1	176	6.0e-54	203	COG0097	Ribosomal protein L6P/L9E	178
641666713	131	58.02	1	130	1	131	1.0e-46	178	COG0096	Ribosomal protein S8	132
641666714	101	59.02	41	101	1	61	3.0e-15	73.3	COG0199	Ribosomal protein S14	61
641666715	183	60.67	6	183	2	179	2.0e-71	261	COG0094	Ribosomal protein L5	180
641666716	105	53.85	1	103	2	103	5.0e-18	82.6	COG0198	Ribosomal protein L24	104
641666717	122	72.13	1	122	1	122	3.0e-48	183	COG0093	Ribosomal protein L14	122
641666719	504	53.17	63	503	2	403	3.0e-109	389	COG0004	Ammonia channel protein AmtB	409
641666720	112	75	1	112	1	112	4.0e-39	153	COG0347	Nitrogen regulatory protein PII	112
641666721	504	57.23	15	499	1	486	0.0e+00	543	COG0606	Predicted ATPase with chaperone activity	490
641666722	247	39.83	4	242	5	242	2.0e-51	195	COG1385	16S rRNA U1498 N3-methylase RsmE	246
641666723	624	60.26	11	623	9	607	0.0e+00	881	COG1274	Phosphoenolpyruvate carboxykinase, GTP-dependent	608
641666725	321	27.04	6	311	1	296	2.0e-24	107	COG0583	DNA-binding transcriptional regulator, LysR family	297
641666726	702	44.28	7	696	1	648	0.0e+00	650	COG1505	Prolyl oligopeptidase PreP, S9A serine peptidase family	648
641666727	160	40.91	15	158	1	153	2.0e-31	128	COG0319	ssRNA-specific RNase YbeY, 16S rRNA maturation enzyme	153
641666728	374	52.63	39	361	19	331	9.0e-99	353	COG1702	Phosphate starvation-inducible protein PhoH, predicted ATPase	348
641666729	625	21.08	272	625	9	365	6.0e-27	116	COG4585	Signal transduction histidine kinase	365
641666730	222	34.56	3	219	2	208	6.0e-38	150	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
641666731	191	48	1	189	1	200	2.0e-53	202	COG0632	Holliday junction resolvasome RuvABC DNA-binding subunit	201
641666732	363	72.73	21	350	3	331	0.0e+00	528	COG2255	Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit	332
641666733	240	40.1	7	206	3	203	3.0e-43	168	COG0406	Broad specificity phosphatase PhoE	208
641666735	241	25.12	37	241	37	250	3.0e-20	92.3	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
641666736	441	39.86	1	433	1	421	7.0e-97	348	COG0044	Dihydroorotase or related cyclic amidohydrolase	430
641666737	320	48.9	9	317	1	312	2.0e-99	356	COG0540	Aspartate carbamoyltransferase, catalytic chain	316
641666738	169	40.41	5	144	7	152	1.0e-31	129	COG2065	Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase	179
641666739	149	35.56	15	137	2	136	9.0e-26	109	COG0816	RNase H-fold protein, predicted Holliday junction resolvase in Firmicutes and mycoplasms, involved in anti-termination at Rho-dependent terminators	141
641666740	193	53.09	1	193	5	194	3.0e-61	228	COG1678	Putative transcriptional regulator, AlgH/UPF0301 family	194
641666741	511	42.65	34	506	5	461	4.0e-119	422	COG0415	Deoxyribodipyrimidine photolyase	461
641666742	1035	32.2	2	1008	1	1008	0.0e+00	787	COG0841	Multidrug efflux pump subunit AcrB	1009
641666745	2414	30.08	1581	2264	2	715	2.0e-108	388	COG0643	Chemotaxis protein histidine kinase CheA	716
641666746	777	35.54	446	776	80	408	1.0e-44	175	COG0840	Methyl-accepting chemotaxis protein	408
641666747	176	24.7	13	174	5	162	5.0e-11	61.1	COG0835	Chemotaxis signal transduction protein	165
641666750	50	52	1	50	5	54	1.0e-12	64.5	COG1773	Rubredoxin	55
641666751	310	28.17	29	271	12	252	3.0e-31	129	COG0351	Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase	263
641666752	437	58.1	6	436	5	427	0.0e+00	547	COG0001	Glutamate-1-semialdehyde aminotransferase	432
641666753	291	33.58	22	291	23	286	3.0e-45	175	COG0676	D-hexose-6-phosphate mutarotase	287
641666754	362	41.77	13	332	4	309	4.0e-80	291	COG0205	6-phosphofructokinase	347
641666755	480	40	2	478	9	459	8.0e-122	430	COG0773	UDP-N-acetylmuramate-alanine ligase	459
641666756	207	36.17	16	203	2	188	3.0e-45	175	COG3150	Predicted esterase YcpF, UPF0227 family	191
641666757	246	46.85	1	245	1	251	7.0e-48	184	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
641666758	705	19.77	43	642	33	699	7.0e-50	192	COG0557	Exoribonuclease R	706
641666762	195	33.04	65	175	17	125	5.0e-11	61.1	COG0526	Thiol-disulfide isomerase or thioredoxin	127
641666763	151	41.78	6	151	1	139	9.0e-25	106	COG0511	Biotin carboxyl carrier protein	140
641666764	451	65.77	1	445	1	446	0.0e+00	618	COG0439	Biotin carboxylase	449
641666765	301	40.39	3	300	6	299	3.0e-63	235	COG2264	Ribosomal protein L11 methylase PrmA	300
641666767	168	49.4	1	165	2	164	3.0e-53	200	COG0678	Peroxiredoxin	165
641666768	98	61.54	19	96	9	86	2.0e-20	91	COG0186	Ribosomal protein S17	87
641666769	65	51.56	2	65	4	67	3.0e-07	46.8	COG0255	Ribosomal protein L29	69
641666770	138	59.56	1	134	2	137	6.0e-45	173	COG0197	Ribosomal protein L16/L10AE	146
641666771	285	58.87	12	241	1	231	1.0e-75	276	COG0092	Ribosomal protein S3	233
641666772	109	59.26	1	108	9	116	4.0e-31	126	COG0091	Ribosomal protein L22	120
641666773	91	72.83	1	91	1	92	4.0e-35	139	COG0185	Ribosomal protein S19	93
641666774	274	58.55	1	274	1	275	1.0e-105	376	COG0090	Ribosomal protein L2	275
641666775	108	53.19	15	107	1	94	3.0e-21	93.7	COG0089	Ribosomal protein L23	94
641666776	206	39.52	1	206	2	211	4.0e-54	204	COG0088	Ribosomal protein L4	214
641666777	226	55.96	9	225	1	218	4.0e-71	261	COG0087	Ribosomal protein L3	218
641666781	774	30.09	10	746	9	706	2.0e-120	427	COG5000	Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation	712
641666783	453	36.21	109	451	3	353	6.0e-72	265	COG0144	16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family	355
641666785	186	26.74	1	184	1	173	9.0e-15	73.4	COG1704	Uncharacterized conserved protein	185
641666786	235	39.74	6	233	3	213	2.0e-57	215	COG0603	7-cyano-7-deazaguanine synthase (queuosine biosynthesis)	222
641666787	439	53.81	19	438	1	416	0.0e+00	548	COG0014	Gamma-glutamyl phosphate reductase	417
641666788	346	42.86	3	336	2	329	3.0e-126	444	COG1087	UDP-glucose 4-epimerase	329
641666789	172	19.39	8	172	2	160	2.0e-07	48.7	COG3165	Ubiquinone biosynthesis protein UbiJ, contains SCP2 domain	204
641666790	522	46.93	1	515	4	517	0.0e+00	484	COG0661	Predicted unusual protein kinase regulating ubiquinone biosynthesis, AarF/ABC1/UbiB family	517
641666791	108	43.42	1	76	8	82	7.0e-19	85.5	COG2331	Predicted nucleic acid-binding protein, contains Zn-ribbon domain	82
641666792	219	48.28	1	203	6	201	4.0e-54	204	COG2928	Uncharacterized membrane protein	222
641666793	598	60.84	1	591	1	584	0.0e+00	908	COG0173	Aspartyl-tRNA synthetase	585
641666794	306	26	7	300	9	298	6.0e-25	108	COG1575	1,4-dihydroxy-2-naphthoate octaprenyltransferase	303
641666795	163	18.94	18	147	15	138	5.0e-06	44.2	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
641666796	276	32.3	28	274	9	256	6.0e-30	124	COG3568	Metal-dependent hydrolase, endonuclease/exonuclease/phosphatase family	259
641666797	451	28.88	19	432	29	430	3.0e-54	206	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
641666798	291	31.19	1	289	15	295	2.0e-37	149	COG0501	Zn-dependent protease with chaperone function	302
641666800	344	63.85	1	342	1	343	0.0e+00	519	COG0418	Dihydroorotase	344
641666801	244	61.16	1	242	2	240	7.0e-107	380	COG1126	ABC-type polar amino acid transport system, ATPase component	240
641666802	221	41.26	1	221	1	222	4.0e-47	181	COG0765	ABC-type amino acid transport system, permease component	222
641666803	247	34.43	30	241	13	222	1.0e-44	173	COG0765	ABC-type amino acid transport system, permease component	222
641666804	298	27.17	1	270	4	272	6.0e-32	131	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
641666805	316	26.62	1	292	1	281	3.0e-21	95.8	COG0583	DNA-binding transcriptional regulator, LysR family	297
641666806	619	59.07	101	595	1	496	0.0e+00	632	COG5265	ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components	497
641666807	155	43.85	26	155	11	138	8.0e-34	136	COG1607	Acyl-CoA hydrolase	157
641666808	280	20	45	241	10	209	3.0e-06	45.7	COG2755	Lysophospholipase L1 or related esterase	216
641666809	254	36.22	1	250	5	257	4.0e-46	178	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
641666810	399	40.83	6	399	2	392	4.0e-82	298	COG0183	Acetyl-CoA acetyltransferase	392
641666811	801	30.95	505	712	25	208	6.0e-17	83.2	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
641666811	801	37.7	6	307	3	292	6.0e-64	239	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
641666812	596	31.95	37	464	7	393	1.0e-65	244	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
641666813	219	15.68	15	199	4	188	1.0e-05	43.5	COG1309	DNA-binding transcriptional regulator, AcrR family	201
641666815	159	31.08	4	147	6	153	1.0e-15	75.8	COG3133	Outer membrane lipoprotein SlyB	154
641666818	726	40.87	127	700	3	565	0.0e+00	491	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
641666819	727	21.56	165	481	1	317	6.0e-20	93	COG1181	D-alanine-D-alanine ligase and related ATP-grasp enzymes	317
641666820	865	24.1	152	464	1	312	4.0e-33	137	COG1181	D-alanine-D-alanine ligase and related ATP-grasp enzymes	317
641666820	865	26.53	473	858	89	460	3.0e-43	170	COG0769	UDP-N-acetylmuramyl tripeptide synthase	475
641666821	302	50.5	1	299	1	291	5.0e-98	350	COG2321	Predicted metalloprotease	295
641666822	644	37.53	277	640	20	408	2.0e-46	181	COG0840	Methyl-accepting chemotaxis protein	408
641666824	166	24.16	28	162	8	152	2.0e-10	59.1	COG1225	Peroxiredoxin	157
641666825	490	53.93	10	489	6	481	0.0e+00	661	COG0064	Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit	483
641666827	231	38.6	14	227	2	201	3.0e-46	178	COG0461	Orotate phosphoribosyltransferase	201
641666828	262	41.11	1	260	1	261	9.0e-70	257	COG0708	Exonuclease III	261
641666829	378	28.04	2	368	8	323	7.0e-25	108	COG0391	Archaeal 2-phospho-L-lactate transferase/Bacterial gluconeogenesis factor, CofD/UPF0052 family	323
641666831	212	32.11	1	211	11	228	7.0e-31	127	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
641666832	197	34.71	29	196	2	157	3.0e-25	108	COG3521	Predicted component of the type VI protein secretion system	159
641666833	445	45.96	1	444	1	445	4.0e-116	411	COG3522	Predicted component of the type VI protein secretion system	446
641666834	460	28.96	252	433	14	187	2.0e-17	84.1	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
641666834	460	45.31	27	281	10	259	6.0e-51	195	COG3455	Type VI protein secretion system component VasF	262
641666835	1220	38.83	11	1217	12	1184	0.0e+00	789	COG3523	Type VI protein secretion system component VasK	1188
641666836	231	29.15	5	227	8	212	8.0e-21	94	COG3913	Uncharacterized protein	227
641666837	657	23.13	96	366	1	273	4.0e-27	116	COG0515	Serine/threonine protein kinase	384
641666841	255	29.32	1	244	5	249	5.0e-32	131	COG0631	Serine/threonine protein phosphatase PrpC	262
641666842	580	24.68	255	551	127	427	1.0e-28	121	COG3456	Predicted component of the type VI protein secretion system, contains a FHA domain	430
641666844	543	32.63	10	270	1	278	4.0e-44	173	COG0515	Serine/threonine protein kinase	384
641666845	290	42.25	219	289	14	83	3.0e-06	46.2	COG2770	HAMP domain	83
641666847	1333	39.76	656	908	85	326	3.0e-38	154	COG0642	Signal transduction histidine kinase	336
641666848	471	34.47	1	234	1	225	1.0e-40	161	COG0569	Trk K+ transport system, NAD-binding component	225
641666849	485	39.84	4	484	3	487	3.0e-84	306	COG0168	Trk-type K+ transport system, membrane component	499
641666851	373	29.86	5	364	2	363	2.0e-42	167	COG5351	Uncharacterized protein	367
641666858	771	41.03	13	553	22	547	0.0e+00	512	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
641666859	456	37.68	174	455	6	285	2.0e-48	187	COG4976	Predicted methyltransferase, contains TPR repeat	287
641666862	916	40.09	12	902	1	781	0.0e+00	770	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
641666863	377	44.2	30	348	12	321	2.0e-69	256	COG3520	Predicted component of the type VI protein secretion system	335
641666864	638	40.25	5	638	1	621	0.0e+00	506	COG3519	Type VI protein secretion system component VasA	621
641666865	184	34.97	6	167	3	157	1.0e-20	92.7	COG3518	Predicted component of the type VI protein secretion system	157
641666866	174	27.33	5	159	4	150	1.0e-19	89.6	COG3157	Type VI protein secretion system component Hcp (secreted cytotoxin)	162
641666867	161	35.54	1	158	1	160	2.0e-31	128	COG3157	Type VI protein secretion system component Hcp (secreted cytotoxin)	162
641666868	498	61.49	1	496	2	494	0.0e+00	759	COG3517	Predicted component of the type VI protein secretion system	495
641666869	168	54.17	2	168	1	168	3.0e-55	207	COG3516	Predicted component of the type VI protein secretion system	169
641666870	345	29.68	8	345	6	345	6.0e-25	108	COG3515	Predicted component of the type VI protein secretion system	346
641666872	545	27.46	27	542	50	553	3.0e-53	203	COG2831	Hemolysin activation/secretion protein	554
641666873	729	28.06	345	723	50	420	6.0e-43	169	COG4995	Uncharacterized conserved protein, contains CHAT domain	420
641666874	604	30.54	126	457	9	325	8.0e-37	148	COG0642	Signal transduction histidine kinase	336
641666875	239	32.37	33	239	2	204	3.0e-30	125	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
641666877	237	37.62	32	229	9	210	7.0e-31	127	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
641666878	1377	20.71	512	1206	1	704	9.0e-49	189	COG3899	Predicted ATPase	849
641666879	648	22.02	52	486	47	407	2.0e-08	54.3	COG2124	Cytochrome P450	411
641666884	170	37.5	10	164	1	159	1.0e-31	129	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
641666886	284	26.05	18	277	14	240	1.0e-25	110	COG0284	Orotidine-5'-phosphate decarboxylase	240
641666888	427	21.03	1	419	2	364	5.0e-16	79.3	COG4637	Predicted ATPase	373
641666889	457	32.24	13	457	1	436	3.0e-99	355	COG0015	Adenylosuccinate lyase	438
641666891	801	31.49	49	389	9	336	6.0e-39	156	COG0642	Signal transduction histidine kinase	336
641666894	124	30.19	19	122	22	126	2.0e-07	48	COG2010	Cytochrome c, mono- and diheme variants	150
641666895	465	47.19	5	465	6	461	0.0e+00	463	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
641666899	274	25.94	25	273	15	280	7.0e-06	45	COG0755	ABC-type transport system involved in cytochrome c biogenesis, permease component	281
641666908	350	42.39	10	101	31	121	7.0e-12	65.1	COG3245	Cytochrome c5	126
641666911	359	20.79	46	331	6	295	6.0e-09	55.5	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
641666914	286	25.2	24	147	1	118	8.0e-06	44.6	COG2863	Cytochrome c553	121
641666917	309	27.69	63	303	2	236	4.0e-23	101	COG3629	DNA-binding transcriptional activator of the SARP family	280
641666918	243	28.44	19	229	2	212	4.0e-25	108	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
641666919	375	27.17	25	374	29	364	2.0e-56	213	COG0075	Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism protein PucG	383
641666921	295	36.91	56	288	19	232	4.0e-23	101	COG2801	Transposase InsO and inactivated derivatives	232
641666922	99	28.71	1	99	1	99	6.0e-06	42.5	COG2963	Transposase and inactivated derivatives	116
641666929	347	25.91	83	296	23	224	4.0e-09	55.8	COG2801	Transposase InsO and inactivated derivatives	232
641666931	363	22.27	69	301	8	225	2.0e-09	57.3	COG2801	Transposase InsO and inactivated derivatives	232
641666932	176	32.19	41	171	9	154	5.0e-08	51.1	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
641666933	323	29.32	56	317	1	247	4.0e-38	151	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
641666935	309	26.82	1	301	1	297	9.0e-23	101	COG0583	DNA-binding transcriptional regulator, LysR family	297
641666937	151	27.66	3	126	1	138	2.0e-08	51.8	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
641666938	130	30.19	26	128	35	132	2.0e-08	51.6	COG5649	Uncharacterized protein	132
641666941	310	31.79	4	300	2	297	3.0e-34	138	COG0583	DNA-binding transcriptional regulator, LysR family	297
641666942	239	29.46	16	235	6	225	1.0e-22	99	COG1011	FMN phosphatase YigB, HAD superfamily	229
641666943	734	42.05	241	732	91	543	0.0e+00	478	COG2225	Malate synthase	545
641666945	366	47.45	14	346	1	322	2.0e-94	339	COG3943	Uncharacterized conserved protein	329
641666946	553	23.57	34	409	111	532	2.0e-31	130	COG2189	Adenine specific DNA methylase Mod	590
641666950	400	20.75	28	398	34	394	1.0e-14	74.5	COG2814	Predicted arabinose efflux permease, MFS family	394
641666954	490	26.07	19	250	3	232	2.0e-15	77.3	COG2202	PAS domain	232
641666954	490	36.54	234	488	78	328	1.0e-42	167	COG0642	Signal transduction histidine kinase	336
641666955	229	39.56	42	221	4	185	1.0e-26	113	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
641666956	324	35.97	55	324	48	324	3.0e-51	195	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
641666957	440	33.65	11	426	5	381	3.0e-80	292	COG0116	23S rRNA G2445 N2-methylase RlmL	381
641666958	110	50.85	1	59	1	59	6.0e-13	65.7	COG3422	Uncharacterized conserved protein YegP, UPF0339 family	59
641666959	144	28.47	8	142	7	133	2.0e-11	61.5	COG3607	Predicted lactoylglutathione lyase	133
641666960	492	35.1	24	492	4	458	3.0e-86	312	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
641666962	241	35.86	1	233	3	234	6.0e-52	197	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
641666965	152	43.7	24	139	1	119	8.0e-20	89.7	COG0599	Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family	124
641666967	110	34.86	1	109	1	109	1.0e-17	81.5	COG4634	Predicted nuclease, contains PIN domain, potential toxin-antitoxin system component	113
641666968	76	56.34	1	71	6	76	4.0e-20	89.6	COG2442	Uncharacterized conserved protein, DUF433 family	79
641666969	1935	43.25	17	983	6	932	0.0e+00	1097	COG0178	Excinuclease UvrABC ATPase subunit	935
641666971	221	25.15	37	197	24	177	5.0e-11	61.6	COG3318	Uncharacterized conserved protein YecA, UPF0149 family, contains C-terminal Zn-binding SEC-C motif	216
641666973	685	61.23	3	651	1	620	0.0e+00	955	COG0445	tRNA U34 5-carboxymethylaminomethyl modifying enzyme MnmG/GidA	621
641666974	218	40.28	5	213	2	213	3.0e-46	178	COG0357	16S rRNA G527 N7-methylase RsmG (former glucose-inhibited division protein B)	215
641666975	203	33.82	3	202	2	204	4.0e-21	94.9	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
641666976	256	40	1	253	1	254	2.0e-58	219	COG1192	Cellulose biosynthesis protein BcsQ	259
641666977	363	22.49	53	301	31	237	2.0e-13	70.3	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
641666978	149	28	21	143	1	123	7.0e-15	73.2	COG0789	DNA-binding transcriptional regulator, MerR family	124
641666979	154	25.69	6	149	2	140	1.0e-19	89.3	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
641666980	220	41.12	4	196	3	199	5.0e-51	194	COG0288	Carbonic anhydrase	207
641666981	603	46.53	11	586	6	574	0.0e+00	710	COG4579	Isocitrate dehydrogenase kinase/phosphatase	578
641666982	395	41.35	6	392	2	388	1.0e-67	250	COG0183	Acetyl-CoA acetyltransferase	392
641666983	237	35.78	4	235	2	206	3.0e-19	88.8	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
641666984	376	46.09	1	375	3	386	2.0e-94	339	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
641666986	311	45.51	1	309	1	308	1.0e-86	313	COG1715	Restriction endonuclease Mrr	308
641666987	1110	38.1	443	713	76	336	2.0e-40	162	COG0642	Signal transduction histidine kinase	336
641666989	757	35.29	487	757	71	333	4.0e-40	160	COG0642	Signal transduction histidine kinase	336
641666990	284	19.37	10	246	16	268	4.0e-19	88.9	COG3221	ABC-type phosphate/phosphonate transport system, periplasmic component	299
641666991	419	49.16	1	417	1	406	0.0e+00	469	COG4553	Poly-beta-hydroxyalkanoate depolymerase	415
641666992	220	27.7	7	212	1	211	2.0e-21	96	COG0625	Glutathione S-transferase	211
641666993	138	17.65	8	125	2	120	2.0e-06	45.4	COG0662	Mannose-6-phosphate isomerase, cupin superfamily	127
641666994	305	33.77	5	301	5	293	6.0e-36	145	COG2971	BadF-type ATPase, related to human N-acetylglucosamine kinase	301
641666995	372	47.61	7	370	5	377	4.0e-90	325	COG1820	N-acetylglucosamine-6-phosphate deacetylase	380
641666996	370	39.61	6	359	1	357	2.0e-102	365	COG4663	TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component	363
641666997	207	36.87	1	179	4	180	2.0e-43	168	COG4665	TRAP-type mannitol/chloroaromatic compound transport system, small permease component	182
641666999	207	29.7	44	204	51	215	2.0e-13	69.6	COG3235	Uncharacterized membrane protein	223
641667000	201	34.85	4	200	7	203	1.0e-36	146	COG3917	2-hydroxychromene-2-carboxylate isomerase	203
641667002	536	40.37	1	534	1	441	3.0e-119	422	COG1508	DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog	444
641667003	268	66.4	22	268	1	243	8.0e-105	373	COG1137	ABC-type lipopolysaccharide export system, ATPase component	243
641667004	211	29.71	37	211	10	172	1.0e-14	73.4	COG1934	Lipopolysaccharide export system protein LptA	173
641667006	213	19.03	8	205	12	256	5.0e-11	61.6	COG3087	Cell division protein FtsN	264
641667007	561	38.54	5	561	4	577	0.0e+00	505	COG0018	Arginyl-tRNA synthetase	577
641667008	444	30.3	15	288	1	287	6.0e-35	142	COG0515	Serine/threonine protein kinase	384
641667010	146	48.98	1	146	4	149	5.0e-33	133	COG1981	Uncharacterized membrane protein	149
641667012	131	52.63	70	126	1	57	3.0e-15	74.2	COG3411	(2Fe-2S) ferredoxin	64
641667013	205	43.43	10	204	9	204	5.0e-49	187	COG2945	Alpha/beta superfamily hydrolase	210
641667014	389	43.52	7	389	8	386	4.0e-96	345	COG1686	D-alanyl-D-alanine carboxypeptidase	389
641667015	303	30.42	14	294	5	276	2.0e-45	176	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
641667016	91	44.58	9	91	8	90	2.0e-22	97.3	COG2921	Putative lipoic acid-binding regulatory protein	90
641667023	904	35.29	18	634	4	595	1.0e-100	361	COG1042	Acyl-CoA synthetase (NDP forming)	598
641667025	552	27.22	388	542	10	189	2.0e-17	84.2	COG4929	Uncharacterized membrane-anchored protein	190
641667027	343	43.06	2	343	1	348	8.0e-99	353	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
641667028	285	30	13	278	3	237	5.0e-49	188	COG0688	Phosphatidylserine decarboxylase	239
641667029	103	39.22	2	103	3	104	3.0e-22	96.9	COG4575	Membrane-anchored ribosome-binding protein, inhibits growth in stationary phase, ElaB/YqjD/DUF883 family	104
641667030	129	26.23	1	121	6	124	2.0e-09	54.5	COG5393	Uncharacterized membrane protein YqjE	131
641667033	131	32.41	28	129	4	111	3.0e-11	61.1	COG2151	Metal-sulfur cluster biosynthetic enzyme	111
641667034	1007	29.64	37	613	106	647	9.0e-100	358	COG0209	Ribonucleotide reductase alpha subunit	696
641667035	132	29.55	1	130	1	128	9.0e-17	79.3	COG5611	Predicted nucleic-acid-binding protein, contains PIN domain	130
641667037	327	38.87	1	312	1	313	3.0e-82	298	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
641667041	310	60.38	16	280	6	270	5.0e-100	357	COG2326	Polyphosphate kinase 2, PPK2 family	270
641667043	407	25.42	59	333	56	350	1.0e-14	74.6	COG1566	Multidrug resistance efflux pump	352
641667045	238	47.79	8	227	1	226	3.0e-73	268	COG1136	ABC-type lipoprotein export system, ATPase component	226
641667046	297	29.29	5	296	1	296	5.0e-32	131	COG0583	DNA-binding transcriptional regulator, LysR family	297
641667047	249	41.09	1	247	1	251	8.0e-41	160	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
641667048	330	42.77	7	330	6	329	4.0e-86	311	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
641667049	175	22.97	20	167	19	166	5.0e-16	77.7	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
641667050	419	44.24	46	418	1	372	4.0e-82	298	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
641667051	287	50.21	6	248	2	243	8.0e-87	313	COG3959	Transketolase, N-terminal subunit	243
641667052	338	42.48	33	337	10	312	4.0e-94	338	COG3958	Transketolase, C-terminal subunit	312
641667053	423	63.83	1	423	6	426	0.0e+00	626	COG2873	O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent	426
641667055	175	30.41	8	155	2	142	1.0e-17	82.6	COG2062	Phosphohistidine phosphatase SixA	163
641667056	415	27.4	36	386	1	355	2.0e-33	136	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
641667059	217	43.07	6	207	3	200	2.0e-55	208	COG4566	Two-component response regulator, FixJ family, consists of REC and HTH domains	202
641667060	113	66.06	5	113	4	112	2.0e-42	163	COG2824	Uncharacterized Zn-ribbon-containing protein	112
641667061	241	49.11	10	233	16	231	5.0e-57	214	COG3148	Uncharacterized conserved protein YfiP, DTW domain	231
641667065	1058	29.31	318	689	24	399	5.0e-56	213	COG1061	Superfamily II DNA or RNA helicase	442
641667068	136	30.83	15	134	22	118	3.0e-12	64.1	COG3671	Uncharacterized membrane protein	125
641667073	295	24.25	1	294	1	297	2.0e-23	102	COG0583	DNA-binding transcriptional regulator, LysR family	297
641667074	321	30.72	5	320	3	319	8.0e-47	180	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
641667075	279	32.11	31	275	1	246	8.0e-45	173	COG1414	DNA-binding transcriptional regulator, IclR family	246
641667076	321	17.99	19	250	6	236	6.0e-12	65.3	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
641667077	578	24.68	35	420	2	377	4.0e-46	179	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
641667079	443	58.69	15	440	8	427	0.0e+00	489	COG3508	Homogentisate 1,2-dioxygenase	427
641667080	445	21.96	65	399	1	259	1.0e-23	105	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
641667081	325	34.08	7	317	2	259	4.0e-46	178	COG1975	Xanthine and CO dehydrogenase maturation factor, XdhC/CoxF family	278
641667082	745	26.91	25	744	1	722	4.0e-92	332	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
641667083	157	51.3	4	157	6	155	7.0e-51	193	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
641667084	302	41.28	184	292	17	125	2.0e-20	93.4	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
641667086	310	25.18	34	303	18	285	2.0e-37	149	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
641667087	336	35.48	3	335	2	342	6.0e-51	194	COG0673	Predicted dehydrogenase	342
641667092	406	41.64	38	405	39	395	1.0e-68	254	COG2133	Glucose/arabinose dehydrogenase, beta-propeller fold	399
641667093	254	37.21	1	248	2	259	4.0e-54	204	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
641667094	343	38.87	42	338	1	296	8.0e-59	221	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
641667095	615	32.87	37	605	8	540	1.0e-71	264	COG1178	ABC-type Fe3+ transport system, permease component	540
641667096	364	47.84	21	364	6	352	1.0e-105	376	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
641667097	460	39.15	24	452	7	447	6.0e-115	408	COG2723	Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase	460
641667098	409	24.24	1	408	3	427	3.0e-27	116	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
641667099	304	31.58	8	291	1	285	1.0e-51	196	COG1175	ABC-type sugar transport system, permease component	295
641667100	312	32.98	28	311	3	281	2.0e-54	206	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
641667101	361	47.47	1	356	1	338	7.0e-111	393	COG3839	ABC-type sugar transport system, ATPase component	338
641667102	351	35.71	2	336	1	333	2.0e-71	262	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
641667103	357	26.78	1	342	2	340	2.0e-41	163	COG0673	Predicted dehydrogenase	342
641667104	249	19.71	1	249	1	273	5.0e-16	78.3	COG1082	Sugar phosphate isomerase/epimerase	274
641667105	352	26.02	8	326	1	274	5.0e-29	122	COG1082	Sugar phosphate isomerase/epimerase	274
641667106	387	28.65	8	354	2	321	8.0e-44	171	COG0673	Predicted dehydrogenase	342
641667107	836	31.29	26	352	48	367	1.0e-52	201	COG1472	Periplasmic beta-glucosidase and related glycosidases	397
641667108	534	33.51	189	527	42	408	4.0e-44	172	COG0840	Methyl-accepting chemotaxis protein	408
641667111	139	33.81	1	139	3	132	1.0e-14	72.5	COG1487	Predicted nucleic acid-binding protein, contains PIN domain	133
641667112	84	44.74	1	76	1	76	2.0e-12	64.3	COG4691	Plasmid stability protein	80
641667113	219	42.36	11	213	2	200	2.0e-39	155	COG1279	Arginine exporter protein ArgO	202
641667114	216	50.97	1	206	1	205	1.0e-59	222	COG2808	Predicted FMN-binding regulatory protein PaiB	209
641667115	456	43.56	8	455	2	464	0.0e+00	483	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
641667116	600	43	17	583	1	600	4.0e-122	432	COG4191	Signal transduction histidine kinase regulating C4-dicarboxylate transport system	603
641667117	447	51.95	9	413	3	404	7.0e-109	387	COG1301	Na+/H+-dicarboxylate symporter	415
641667119	274	33.71	7	266	4	251	5.0e-11	62	COG0730	Uncharacterized membrane protein YfcA	258
641667120	218	42.06	5	215	4	216	6.0e-32	130	COG1802	DNA-binding transcriptional regulator, GntR family	230
641667121	303	34.18	1	302	4	319	4.0e-52	198	COG2423	Ornithine cyclodeaminase/archaeal alanine dehydrogenase, mu-crystallin family	330
641667122	242	37.9	11	226	4	221	5.0e-28	118	COG1802	DNA-binding transcriptional regulator, GntR family	230
641667124	111	28.09	18	105	2	90	2.0e-10	58.1	COG0633	Ferredoxin	102
641667126	111	26.32	3	93	5	93	6.0e-09	52.7	COG0633	Ferredoxin	102
641667127	243	27.54	5	237	6	237	5.0e-23	101	COG5424	Pyrroloquinoline quinone (PQQ) biosynthesis protein C	242
641667128	491	46.09	18	488	5	466	7.0e-126	444	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
641667129	159	39.29	1	140	2	137	8.0e-23	99	COG3193	Uncharacterized conserved protein GlcG, DUF336 family	141
641667130	331	33.64	99	317	6	216	9.0e-42	164	COG0543	NAD(P)H-flavin reductase	252
641667130	331	34.67	16	86	19	93	1.0e-11	64.7	COG0633	Ferredoxin	102
641667132	494	33.7	10	493	6	538	1.0e-98	354	COG0405	Gamma-glutamyltranspeptidase	539
641667133	205	33.5	3	198	1	201	3.0e-26	111	COG0625	Glutathione S-transferase	211
641667134	327	45.07	6	308	5	296	5.0e-74	271	COG3491	Isopenicillin N synthase and related dioxygenases	322
641667136	558	27.11	92	402	16	316	5.0e-31	129	COG0226	ABC-type phosphate transport system, periplasmic component	318
641667137	389	34.62	6	183	1	180	7.0e-33	135	COG0518	GMP synthase - Glutamine amidotransferase domain	198
641667137	389	35.4	271	383	1	112	2.0e-18	87.3	COG3795	Uncharacterized conserved protein	123
641667138	137	45.16	1	122	1	120	2.0e-25	108	COG3795	Uncharacterized conserved protein	123
641667139	140	51.52	1	132	1	132	2.0e-45	174	COG3607	Predicted lactoylglutathione lyase	133
641667140	428	53.57	9	428	4	413	2.0e-108	385	COG4941	Predicted RNA polymerase sigma factor, contains C-terminal TPR domain	415
641667142	417	45.43	1	400	29	429	8.0e-101	361	COG0513	Superfamily II DNA and RNA helicase	513
641667144	164	45.67	40	164	5	131	2.0e-44	171	COG0229	Peptide methionine sulfoxide reductase MsrB	140
641667146	251	24.34	20	249	4	251	3.0e-11	62.2	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
641667147	634	20.75	208	562	62	412	3.0e-20	94.2	COG1032	Radical SAM superfamily enzyme YgiQ, UPF0313 family	490
641667148	589	36.19	281	589	26	333	1.0e-48	188	COG0642	Signal transduction histidine kinase	336
641667150	439	54.28	38	438	1	401	1.0e-110	393	COG0004	Ammonia channel protein AmtB	409
641667152	191	42.01	1	169	1	159	2.0e-36	145	COG2258	Uncharacterized conserved protein YiiM, contains MOSC domain	210
641667154	233	28.38	13	233	2	207	2.0e-34	139	COG0400	Predicted esterase	207
641667155	230	43.57	1	230	1	235	3.0e-45	175	COG0412	Dienelactone hydrolase	236
641667157	254	41.58	56	239	25	211	1.0e-34	139	COG4305	Peptidoglycan-binding domain, expansin	232
641667158	417	25.08	8	308	6	257	8.0e-26	111	COG2070	NAD(P)H-dependent flavin oxidoreductase YrpB, nitropropane dioxygenase family	336
641667159	745	73.39	1	744	1	743	0.0e+00	1247	COG2838	Monomeric isocitrate dehydrogenase	744
641667161	479	48.22	6	479	4	454	0.0e+00	482	COG0486	tRNA U34 5-carboxymethylaminomethyl modifying GTPase MnmE/TrmE	454
641667162	559	43.2	272	555	6	297	1.0e-72	267	COG0706	Membrane protein insertase Oxa1/YidC/SpoIIIJ, required for the localization of integral membrane proteins	314
641667163	112	55.88	12	79	7	74	1.0e-20	91.9	COG0759	Membrane-anchored protein YidD, putatitve component of membrane protein insertase Oxa1/YidC/SpoIIIJ	92
641667164	156	23.48	4	135	6	110	1.0e-05	42.6	COG0594	RNase P protein component	117
