gene_oid	gene_length	percent_identity	query_start	query_end	subj_start	subj_end	evalue	bit_score	cog_id	cog_name	cog_length
643463336	506	49.27	163	502	78	408	2.0e-92	333	COG0593	Chromosomal replication initiation ATPase DnaA	408
643463337	176	55.19	9	162	1	154	4.0e-48	184	COG0817	Holliday junction resolvasome RuvABC endonuclease subunit	160
643463338	209	39.51	1	205	1	200	8.0e-46	176	COG0632	Holliday junction resolvasome RuvABC DNA-binding subunit	201
643463339	352	49.57	1	343	1	337	4.0e-116	411	COG0533	tRNA A37 threonylcarbamoyltransferase TsaD	342
643463340	253	24.18	1	236	2	241	4.0e-19	88.6	COG1587	Uroporphyrinogen-III synthase	248
643463341	410	20.05	33	374	2	350	6.0e-12	65.5	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
643463342	328	29.41	30	321	44	343	8.0e-29	121	COG3391	DNA-binding beta-propeller fold protein YncE	381
643463343	256	38.94	13	236	4	229	6.0e-53	200	COG1131	ABC-type multidrug transport system, ATPase component	293
643463344	280	27.06	52	268	61	275	2.0e-07	49.5	COG0842	ABC-type multidrug transport system, permease component	286
643463345	132	46.09	6	130	10	135	5.0e-30	123	COG3474	Cytochrome c2	135
643463346	351	23	26	317	9	301	2.0e-11	63.7	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
643463347	235	44.2	1	211	3	221	1.0e-53	203	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
643463348	656	41.81	25	650	4	585	0.0e+00	591	COG0514	Superfamily II DNA helicase RecQ	590
643463349	596	51.01	54	595	7	538	0.0e+00	588	COG0405	Gamma-glutamyltranspeptidase	539
643463351	323	37.37	30	310	2	261	4.0e-65	241	COG1291	Flagellar motor component MotA	266
643463352	314	24.04	2	313	20	331	2.0e-35	143	COG1868	Flagellar motor switch protein FliM	332
643463354	344	30.28	16	339	11	337	9.0e-52	197	COG1536	Flagellar motor switch protein FliG	339
643463355	359	33.7	1	359	1	358	3.0e-91	328	COG1377	Flagellar biosynthesis protein FlhB	363
643463357	126	30.3	1	126	2	132	7.0e-22	96.1	COG1815	Flagellar basal body rod protein FlgB	133
643463358	140	44.2	3	137	1	137	1.0e-37	148	COG1558	Flagellar basal body rod protein FlgC	137
643463359	104	32.22	16	104	16	105	9.0e-09	51.9	COG1677	Flagellar hook-basal body complex protein FliE	105
643463360	262	49.62	1	262	2	265	5.0e-74	270	COG4786	Flagellar basal body rod protein FlgG	265
643463362	367	52.57	1	367	1	365	3.0e-111	395	COG1706	Flagellar basal body P-ring protein FlgI	365
643463363	177	36.36	27	175	35	188	1.0e-12	66.2	COG3334	Flagellar motility protein MotE, a chaperone for MotC folding	192
643463364	233	36.36	1	228	1	228	4.0e-54	204	COG2063	Flagellar basal body L-ring protein FlgH	230
643463366	247	48.59	1	247	1	248	2.0e-68	252	COG1338	Flagellar biosynthetic protein FliP	248
643463367	292	26.47	3	260	2	273	5.0e-12	65.1	COG1344	Flagellin and related hook-associated protein FlgL	360
643463368	546	31.51	1	543	3	545	8.0e-93	335	COG1766	Flagellar biosynthesis/type III secretory pathway M-ring protein FliF/YscJ	545
643463375	414	37.24	3	414	1	423	1.0e-69	257	COG1749	Flagellar hook protein FlgE	423
643463376	496	24.87	1	495	1	550	9.0e-46	178	COG1256	Flagellar hook-associated protein FlgK	552
643463377	347	14.85	5	347	3	357	6.0e-10	58.9	COG1344	Flagellin and related hook-associated protein FlgL	360
643463378	115	50.43	1	115	1	115	2.0e-25	107	COG5442	Flagellar biosynthesis regulator FlaF	115
643463379	136	51.88	1	133	5	137	6.0e-36	143	COG5443	Flagellar biosynthesis regulator FlbT	148
643463381	88	42.53	1	87	1	87	8.0e-18	82.1	COG1987	Flagellar biosynthesis protein FliQ	89
643463382	696	46.78	15	696	16	694	0.0e+00	796	COG1298	Flagellar biosynthesis pathway, component FlhA	696
643463383	249	33.19	7	244	12	245	8.0e-33	134	COG1684	Flagellar biosynthesis protein FliR	258
643463391	265	43.3	5	264	1	258	4.0e-49	188	COG0725	ABC-type molybdate transport system, periplasmic component	258
643463392	230	54.67	3	226	1	224	4.0e-61	227	COG4149	ABC-type molybdate transport system, permease component	225
643463393	362	50	1	354	1	351	1.0e-99	356	COG4148	ABC-type molybdate transport system, ATPase component	352
643463394	249	44.22	3	248	2	250	2.0e-46	179	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
643463395	113	28.85	7	110	8	110	4.0e-08	49.8	COG0640	DNA-binding transcriptional regulator, ArsR family	110
643463396	238	52.32	3	238	1	237	1.0e-79	289	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
643463397	265	55.73	3	254	1	250	9.0e-82	296	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
643463398	282	42.25	12	277	28	311	3.0e-35	142	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
643463399	292	41.08	1	291	5	297	1.0e-35	143	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
643463400	376	35.71	19	373	1	361	2.0e-46	180	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
643463403	273	34.08	8	265	2	260	5.0e-41	161	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
643463405	443	33.1	2	428	1	419	3.0e-67	249	COG1519	3-deoxy-D-manno-octulosonic-acid transferase	419
643463406	73	48.48	1	66	2	65	4.0e-14	69.7	COG3908	Uncharacterized protein	77
643463407	255	24.54	22	254	19	282	2.0e-14	72.8	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
643463409	175	54.29	1	175	2	174	4.0e-59	220	COG0663	Carbonic anhydrase or acetyltransferase, isoleucine patch superfamily	176
643463410	797	22.22	31	782	3	727	7.0e-55	209	COG1033	Predicted exporter protein, RND superfamily	727
643463414	321	33.95	13	316	2	314	3.0e-46	179	COG0451	Nucleoside-diphosphate-sugar epimerase	314
643463415	352	74.41	4	343	2	339	0.0e+00	570	COG1089	GDP-D-mannose dehydratase	345
643463416	775	40.92	436	758	5	326	1.0e-87	317	COG0280	Phosphotransacetylase	327
643463416	775	54.34	2	435	10	432	0.0e+00	535	COG0281	Malic enzyme	432
643463417	287	52.67	10	287	2	282	1.0e-91	329	COG0414	Panthothenate synthetase	285
643463418	107	45.21	16	88	6	78	1.0e-18	84.9	COG1254	Acylphosphatase	92
643463421	291	35.9	35	290	51	323	5.0e-45	174	COG2367	Beta-lactamase class A	329
643463422	349	34.15	3	325	1	289	4.0e-61	228	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
643463427	410	32.02	66	291	33	239	2.0e-27	116	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
643463428	431	22.96	13	409	2	375	9.0e-19	88.5	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
643463429	250	45.26	1	229	1	223	4.0e-51	194	COG2135	Putative SOS response-associated peptidase YedK	226
643463430	196	23.57	7	163	8	163	3.0e-07	48.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
643463431	244	47.54	183	243	5	65	9.0e-10	57.3	COG2771	DNA-binding transcriptional regulator, CsgD family	65
643463432	205	32.66	1	197	1	198	2.0e-30	125	COG3916	N-acyl-L-homoserine lactone synthetase	209
643463434	328	44.98	1	325	1	325	9.0e-77	280	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
643463436	141	35.9	1	117	1	117	6.0e-31	126	COG1393	Arsenate reductase and related proteins, glutaredoxin family	117
643463437	350	43.9	1	342	9	342	4.0e-76	278	COG0798	Arsenite efflux pump ArsB, ACR3 family	342
643463438	234	31.12	28	220	1	184	5.0e-37	147	COG0431	NAD(P)H-dependent FMN reductase	184
643463439	205	48.08	1	205	1	205	2.0e-52	199	COG0522	Ribosomal protein S4 or related protein	205
643463440	512	36.94	7	509	10	525	2.0e-100	359	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
643463441	333	32.6	1	317	1	299	2.0e-60	225	COG1893	Ketopantoate reductase	307
643463442	419	19.75	38	411	49	435	2.0e-07	50.2	COG2271	Sugar phosphate permease	448
643463443	292	28.97	12	286	1	288	2.0e-28	119	COG0583	DNA-binding transcriptional regulator, LysR family	297
643463444	402	31.46	196	400	1	204	9.0e-34	138	COG2140	Oxalate decarboxylase/archaeal phosphoglucose isomerase, cupin superfamily	209
643463446	160	43.54	1	144	4	149	5.0e-35	140	COG1513	Cyanate lyase	151
643463449	550	46.37	4	532	1	530	0.0e+00	572	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
643463452	232	36.41	9	224	5	219	3.0e-37	148	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
643463454	241	51.09	7	234	4	227	2.0e-69	255	COG0120	Ribose 5-phosphate isomerase	227
643463455	184	23.08	38	180	23	165	8.0e-09	53.9	COG3184	Uncharacterized protein	183
643463456	474	36.92	2	448	1	454	9.0e-108	384	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
643463457	178	39.77	12	178	6	176	1.0e-27	115	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
643463458	463	68.4	5	447	4	444	0.0e+00	737	COG3200	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase, class II	445
643463459	576	31.78	4	235	2	235	2.0e-37	150	COG0388	Predicted amidohydrolase	274
643463459	576	42.27	261	542	1	268	4.0e-71	262	COG0171	NH3-dependent NAD+ synthetase	268
643463460	456	26.96	17	353	45	389	6.0e-28	118	COG1680	CubicO group peptidase, beta-lactamase class C family	390
643463461	183	37.65	20	179	1	157	2.0e-31	129	COG1225	Peroxiredoxin	157
643463462	314	45.11	2	312	11	326	1.0e-76	279	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
643463463	271	43.68	6	264	5	265	3.0e-69	255	COG0300	Short-chain dehydrogenase	265
643463464	381	23.25	4	354	15	363	8.0e-30	125	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
643463465	453	33.77	5	448	11	466	1.0e-92	333	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
643463467	176	45.28	5	161	4	155	3.0e-38	151	COG3045	Periplasmic catabolite regulation protein CreA (function unknown)	165
643463469	449	50.63	2	448	1	464	0.0e+00	595	COG0215	Cysteinyl-tRNA synthetase	464
643463471	535	35.96	9	437	1	409	7.0e-98	351	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
643463472	354	24.21	163	351	48	237	2.0e-09	57.1	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
643463473	217	41.49	14	197	7	193	4.0e-39	154	COG1611	Predicted Rossmann fold nucleotide-binding protein	205
643463474	672	60.69	128	622	2	497	0.0e+00	653	COG5265	ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components	497
643463475	232	45.54	1	221	15	238	9.0e-59	220	COG0688	Phosphatidylserine decarboxylase	239
643463476	324	29.9	6	301	7	317	1.0e-49	190	COG0616	Periplasmic serine protease, ClpP class	317
643463477	96	50.55	1	91	2	91	4.0e-26	109	COG0776	Bacterial nucleoid DNA-binding protein	94
643463479	242	41.43	3	212	2	207	4.0e-53	201	COG0135	Phosphoribosylanthranilate isomerase	208
643463480	417	67.99	15	416	1	392	0.0e+00	684	COG0133	Tryptophan synthase beta chain	396
643463481	423	24.65	13	422	7	398	2.0e-42	166	COG2133	Glucose/arabinose dehydrogenase, beta-propeller fold	399
643463482	330	50	10	317	10	315	1.0e-103	369	COG0502	Biotin synthase or related enzyme	335
643463484	240	29.22	8	230	2	243	8.0e-25	107	COG2981	Uncharacterized protein involved in cysteine biosynthesis	250
643463485	335	31.82	13	298	4	271	8.0e-28	118	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
643463487	268	39.36	23	266	32	280	2.0e-37	149	COG5473	Uncharacterized membrane protein	290
643463490	250	31.5	36	234	16	212	4.0e-27	115	COG5375	Uncharacterized protein	216
643463491	207	27.53	18	191	2	173	1.0e-18	86.5	COG1934	Lipopolysaccharide export system protein LptA	173
643463492	321	66.67	81	321	1	243	2.0e-108	385	COG1137	ABC-type lipopolysaccharide export system, ATPase component	243
643463493	516	45.07	108	512	42	444	9.0e-124	437	COG1508	DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog	444
643463494	153	40.13	1	150	1	152	1.0e-28	119	COG1762	Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type)	152
643463495	343	40.82	16	330	6	320	1.0e-63	237	COG0837	Glucokinase	320
643463496	538	36.39	37	340	3	296	1.0e-82	301	COG1951	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain	297
643463496	538	45.3	356	536	1	177	4.0e-61	229	COG1838	Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain	184
643463497	232	43.36	10	232	4	229	2.0e-31	129	COG1814	Predicted Fe2+/Mn2+ transporter, VIT1/CCC1 family	229
643463498	182	29.14	8	175	7	181	1.0e-22	99.6	COG3038	Cytochrome b561	181
643463499	181	38.82	31	181	1	150	5.0e-28	117	COG0782	Transcription elongation factor, GreA/GreB family	151
643463500	449	40.14	9	297	1	285	5.0e-73	268	COG3034	Murein L,D-transpeptidase YafK	298
643463501	334	54.63	20	332	3	314	7.0e-118	417	COG0825	Acetyl-CoA carboxylase alpha subunit	317
643463502	1094	34.51	2	1070	1	1009	0.0e+00	821	COG0841	Multidrug efflux pump subunit AcrB	1009
643463503	1036	37.9	2	1018	1	1009	0.0e+00	907	COG0841	Multidrug efflux pump subunit AcrB	1009
643463504	450	31.66	41	415	3	370	2.0e-34	141	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
643463505	490	34.12	17	479	1	456	2.0e-55	210	COG1538	Outer membrane protein TolC	457
643463506	294	39.36	11	197	4	190	3.0e-27	115	COG2717	Periplasmic DMSO/TMAO reductase YedYZ, heme-binding membrane subunit	209
643463508	310	62.06	1	310	5	314	8.0e-118	416	COG0462	Phosphoribosylpyrophosphate synthetase	314
643463509	135	32.09	3	135	40	162	3.0e-14	71.2	COG4731	Uncharacterized conserved protein, DUF2147 family	162
643463512	331	58.69	23	325	1	300	2.0e-109	388	COG0031	Cysteine synthase	300
643463513	436	63.11	1	429	1	426	0.0e+00	574	COG2873	O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent	426
643463518	1230	18.89	6	740	1	594	1.0e-67	252	COG0209	Ribonucleotide reductase alpha subunit	696
643463519	401	22.07	46	398	35	391	3.0e-09	56.4	COG2814	Predicted arabinose efflux permease, MFS family	394
643463520	133	60.8	8	132	1	118	2.0e-33	134	COG3761	NADH:ubiquinone oxidoreductase 17.2 kD subunit	118
643463521	240	48.32	4	150	18	164	1.0e-36	146	COG4765	Uncharacterized protein	164
643463522	524	41.67	51	419	16	347	8.0e-62	231	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
643463523	231	44.74	5	228	1	227	2.0e-58	219	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
643463524	487	29.57	129	470	8	334	6.0e-35	142	COG0642	Signal transduction histidine kinase	336
643463525	979	38.71	12	976	14	961	0.0e+00	732	COG1391	Glutamine synthetase adenylyltransferase	963
643463526	795	32	495	767	71	335	2.0e-39	157	COG0642	Signal transduction histidine kinase	336
643463527	222	39.73	1	222	8	219	2.0e-41	162	COG4122	Predicted O-methyltransferase YrrM	219
643463528	888	37.26	1	882	4	859	0.0e+00	609	COG0308	Aminopeptidase N	859
643463530	325	27.65	39	317	8	300	1.0e-26	114	COG3391	DNA-binding beta-propeller fold protein YncE	381
643463532	474	36.24	17	301	4	289	7.0e-49	188	COG0053	Divalent metal cation (Fe/Co/Zn/Cd) transporter	304
643463533	146	30.43	1	126	1	138	6.0e-12	63.3	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
643463534	257	35.71	8	252	2	251	3.0e-40	158	COG1877	Trehalose-6-phosphatase	266
643463536	352	42.12	1	347	2	339	4.0e-109	388	COG1064	D-arabinose 1-dehydrogenase, Zn-dependent alcohol dehydrogenase family	339
643463538	535	18.69	17	519	7	539	2.0e-25	110	COG2303	Choline dehydrogenase or related flavoprotein	542
643463540	801	56.02	94	787	5	696	0.0e+00	942	COG0855	Polyphosphate kinase	696
643463541	523	29.32	33	494	3	471	7.0e-87	314	COG0248	Exopolyphosphatase/pppGpp-phosphohydrolase	492
643463542	405	44.23	10	371	1	361	9.0e-95	340	COG0349	Ribonuclease D	361
643463543	623	48.95	4	618	1	582	0.0e+00	806	COG0173	Aspartyl-tRNA synthetase	585
643463544	1122	29.62	1	301	9	317	4.0e-38	154	COG1305	Transglutaminase-like enzyme, putative cysteine protease	319
643463544	1122	55.9	285	1122	1	808	0.0e+00	1051	COG4196	Uncharacterized conserved protein, DUF2126 family	808
643463545	1410	34.41	860	1408	1	516	4.0e-95	343	COG1640	4-alpha-glucanotransferase	520
643463545	1410	44.79	3	685	9	691	0.0e+00	694	COG1523	Pullulanase/glycogen debranching enzyme	697
643463546	542	38.72	1	528	4	524	0.0e+00	558	COG0033	Phosphoglucomutase	524
643463547	483	47.52	6	481	3	480	0.0e+00	484	COG0297	Glycogen synthase	487
643463548	417	52.67	6	417	1	390	0.0e+00	508	COG0448	ADP-glucose pyrophosphorylase	393
643463549	739	55.78	111	735	3	626	0.0e+00	744	COG0296	1,4-alpha-glucan branching enzyme	628
643463550	836	45.17	28	829	6	749	0.0e+00	819	COG0058	Glucan phosphorylase	750
643463552	867	32.08	499	704	8	216	3.0e-38	154	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
643463556	166	54.3	14	164	1	150	7.0e-43	166	COG1671	Uncharacterized conserved protein YaiI, UPF0178 family	150
643463557	505	34.52	8	478	38	507	3.0e-94	339	COG0513	Superfamily II DNA and RNA helicase	513
643463558	779	37.56	141	778	8	557	0.0e+00	520	COG1982	Arginine/lysine/ornithine decarboxylase	557
643463559	193	36.75	10	174	4	169	3.0e-35	141	COG1247	L-amino acid N-acyltransferase YncA	169
643463560	537	39.56	19	498	3	493	4.0e-91	329	COG0366	Glycosidase	505
643463561	283	29.73	25	276	1	231	3.0e-28	119	COG0412	Dienelactone hydrolase	236
643463562	324	39.37	20	324	10	323	1.0e-68	253	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
643463566	489	20.66	139	467	51	376	9.0e-14	72	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
643463567	293	38.71	23	293	36	312	1.0e-36	147	COG0657	Acetyl esterase/lipase	312
643463568	321	32.06	1	307	12	323	5.0e-41	162	COG1566	Multidrug resistance efflux pump	352
643463570	340	36.96	7	328	2	258	3.0e-40	159	COG1975	Xanthine and CO dehydrogenase maturation factor, XdhC/CoxF family	278
643463572	281	34.92	5	255	20	270	2.0e-62	232	COG2326	Polyphosphate kinase 2, PPK2 family	270
643463574	1935	20.45	289	1935	88	1620	2.0e-82	302	COG2373	Uncharacterized conserved protein YfaS, alpha-2-macroglobulin family	1621
643463575	810	31.3	122	810	62	732	2.0e-99	357	COG4953	Membrane carboxypeptidase/penicillin-binding protein PbpC	733
643463576	478	40.57	16	466	1	446	8.0e-102	364	COG2031	Short chain fatty acids transporter	446
643463577	315	23.38	67	260	30	226	4.0e-12	65.6	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
643463584	264	51.59	6	254	3	248	2.0e-68	252	COG0476	Molybdopterin or thiamine biosynthesis adenylyltransferase	254
643463585	111	42.05	23	110	1	88	2.0e-18	84.1	COG1925	Phosphotransferase system, HPr and related phosphotransfer proteins	88
643463586	133	38.28	1	125	1	128	6.0e-28	116	COG2893	Phosphotransferase system, mannose/fructose-specific component IIA	143
643463588	611	26.99	262	611	17	330	1.0e-35	144	COG0642	Signal transduction histidine kinase	336
643463589	231	42.17	4	231	3	227	9.0e-55	206	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
643463590	264	37.21	5	132	2	130	2.0e-21	96.1	COG2005	DNA-binding transcriptional regulator ModE (molybdenum-dependent)	130
643463590	264	37.88	125	190	2	67	2.0e-09	56.5	COG3585	Molybdopterin-binding protein	69
643463593	344	23.79	1	332	13	424	8.0e-49	187	COG1236	RNA processing exonuclease, beta-lactamase fold, Cft2 family	427
643463596	890	32.47	1	829	1	802	0.0e+00	722	COG1201	Lhr-like helicase	814
643463597	239	35.16	22	232	7	225	3.0e-41	162	COG1407	Metallophosphoesterase superfamily enzyme	235
643463599	161	35.04	37	151	2	106	3.0e-12	64.8	COG0789	DNA-binding transcriptional regulator, MerR family	124
643463601	714	65.23	1	695	1	692	0.0e+00	1019	COG1185	Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase)	692
643463602	89	61.8	1	89	1	89	4.0e-27	112	COG0184	Ribosomal protein S15P/S13E	89
643463605	236	38.86	10	233	5	211	2.0e-58	218	COG0603	7-cyano-7-deazaguanine synthase (queuosine biosynthesis)	222
643463606	321	41.98	25	313	1	279	1.0e-67	249	COG2816	NADH pyrophosphatase NudC, Nudix superfamily	279
643463607	628	41.15	35	533	3	486	2.0e-120	426	COG2812	DNA polymerase III, gamma/tau subunits	515
643463608	107	49.04	1	104	4	105	3.0e-19	86.8	COG0718	Conserved DNA-binding protein YbaB (function unknown)	105
643463609	201	54.36	7	201	4	198	9.0e-73	266	COG0353	Recombinational DNA repair protein RecR	198
643463610	317	27	77	313	64	291	5.0e-06	45.3	COG5006	Threonine/homoserine efflux transporter RhtA	292
643463611	121	33.06	1	119	6	126	5.0e-18	83.4	COG3324	Predicted enzyme related to lactoylglutathione lyase	127
643463612	385	26.93	34	373	66	413	2.0e-53	202	COG1322	DNA anti-recombination protein (rearrangement mutator) RmuC	448
643463613	288	31.21	1	278	13	293	2.0e-35	142	COG1295	Uncharacterized membrane protein, BrkB/YihY/UPF0761 family (not an RNase)	303
643463615	291	38.89	20	287	8	270	2.0e-54	205	COG1968	Undecaprenyl pyrophosphate phosphatase UppP	270
643463616	468	65.65	6	465	3	462	0.0e+00	717	COG0114	Fumarate hydratase class II	462
643463617	185	37.82	4	153	20	175	8.0e-30	123	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
643463619	274	20.73	1	142	15	178	5.0e-08	52	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
643463622	162	57.41	1	162	1	162	5.0e-45	173	COG3685	Ferritin-like metal-binding protein YciE	167
643463624	403	24.04	62	373	9	340	3.0e-17	83.2	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
643463625	329	47.12	39	314	1	274	1.0e-83	303	COG0313	16S rRNA C1402 (ribose-2'-O) methylase RsmI	275
643463626	124	41.67	13	118	4	111	2.0e-22	98	COG0792	Predicted endonuclease distantly related to archaeal Holliday junction resolvase	114
643463627	323	62.9	15	323	13	322	1.0e-112	399	COG4111	Uncharacterized conserved protein	322
643463628	345	52.38	37	345	10	323	4.0e-113	401	COG0379	Quinolinate synthase	324
643463629	506	51.6	8	488	11	508	0.0e+00	522	COG0029	Aspartate oxidase	518
643463630	282	58.57	5	282	1	279	1.0e-95	342	COG0157	Nicotinate-nucleotide pyrophosphorylase	280
643463632	272	70.21	122	262	3	143	8.0e-52	197	COG4275	Uncharacterized protein	143
643463633	467	39.53	17	186	5	176	2.0e-31	130	COG2059	Chromate transport protein ChrA	195
643463634	157	23.94	22	154	5	141	9.0e-09	53.1	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
643463636	296	44.68	10	286	1	278	1.0e-75	276	COG3220	Uncharacterized conserved protein, UPF0276 family	282
643463637	98	54.64	1	95	6	102	8.0e-16	75.2	COG5572	Uncharacterized membrane protein	104
643463638	185	32.4	10	181	2	176	8.0e-21	93.6	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
643463639	210	42.72	1	210	1	213	1.0e-35	143	COG4944	Uncharacterized protein	213
643463640	571	35.97	20	566	1	522	7.0e-114	404	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
643463642	524	48.03	5	524	2	529	0.0e+00	603	COG3131	Periplasmic glucans biosynthesis protein	534
643463643	328	27.08	5	328	12	322	2.0e-53	202	COG0598	Mg2+ and Co2+ transporter CorA	322
643463644	234	34.38	3	217	66	289	5.0e-48	184	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
643463645	322	31.28	71	275	31	241	1.0e-18	87.8	COG0790	TPR repeat	292
643463646	210	26.79	1	204	3	209	2.0e-20	93.1	COG0352	Thiamine monophosphate synthase	211
643463647	161	42.48	7	159	3	154	3.0e-41	161	COG1952	Preprotein translocase subunit SecB	157
643463648	97	34.02	1	96	2	97	2.0e-12	64.1	COG1669	Predicted nucleotidyltransferase	97
643463649	120	34.26	10	117	10	117	2.0e-15	74.6	COG2361	Uncharacterized conserved protein, contains HEPN domain	117
643463650	644	62.05	9	621	12	620	0.0e+00	707	COG4547	Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide:5, 6-dimethylbenzimidazole phosphorib...	620
643463651	332	17.67	23	330	1	303	2.0e-39	156	COG0714	MoxR-like ATPase	329
643463653	108	46.07	20	108	8	86	1.0e-18	85	COG0271	Stress-induced morphogen (activity unknown)	90
643463655	186	64.64	7	186	2	182	4.0e-66	244	COG4567	Two-component response regulator, ActR/RegA family, consists of REC and Fis-type HTH domains	182
643463656	444	23.4	129	432	37	334	3.0e-18	86.8	COG0642	Signal transduction histidine kinase	336
643463657	427	61.12	4	412	1	403	0.0e+00	571	COG4553	Poly-beta-hydroxyalkanoate depolymerase	415
643463658	263	29.24	18	253	1	222	2.0e-40	159	COG1451	Predicted metal-dependent hydrolase	223
643463659	96	53.42	1	73	1	73	4.0e-18	83	COG0227	Ribosomal protein L28	77
643463661	881	30.76	19	866	5	853	0.0e+00	506	COG1674	DNA segregation ATPase FtsK/SpoIIIE and related proteins	858
643463662	385	50.25	1	383	2	394	4.0e-125	441	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
643463663	227	24	51	218	27	200	2.0e-18	85.8	COG2834	Outer membrane lipoprotein-sorting protein	211
643463664	270	39.78	3	269	1	260	7.0e-71	260	COG0708	Exonuclease III	261
643463666	228	39.57	5	228	1	227	4.0e-48	184	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
643463667	296	26.42	77	284	3	212	3.0e-21	96.1	COG1910	Periplasmic molybdate-binding protein/domain	223
643463668	179	45.16	24	178	64	215	1.0e-40	159	COG3786	L,D-peptidoglycan transpeptidase YkuD, ErfK/YbiS/YcfS/YnhG family	217
643463669	230	44.49	10	228	2	227	3.0e-70	258	COG0325	Uncharacterized pyridoxal phosphate-containing protein, affects Ilv metabolism, UPF0001 family	228
643463670	876	45.39	4	876	3	814	0.0e+00	970	COG0495	Leucyl-tRNA synthetase	814
643463671	179	34.48	12	178	2	172	6.0e-22	97	COG5468	Predicted secreted (periplasmic) protein	172
643463673	338	25.66	4	332	1	334	1.0e-36	147	COG1466	DNA polymerase III, delta subunit	334
643463674	188	33.9	9	185	5	178	2.0e-29	122	COG0712	FoF1-type ATP synthase, delta subunit	178
643463675	509	68.37	1	509	1	501	0.0e+00	815	COG0056	FoF1-type ATP synthase, alpha subunit	504
643463676	291	46.55	5	291	1	286	9.0e-85	307	COG0224	FoF1-type ATP synthase, gamma subunit	287
643463677	483	75.1	10	481	3	468	0.0e+00	800	COG0055	FoF1-type ATP synthase, beta subunit	468
643463678	133	40.15	1	130	1	132	8.0e-25	106	COG0355	FoF1-type ATP synthase, epsilon subunit	135
643463679	119	27.78	1	119	7	128	4.0e-12	63.5	COG3794	Plastocyanin	128
643463682	589	31.11	269	358	7	95	4.0e-15	76.6	COG0633	Ferredoxin	102
643463683	602	40	3	495	1	528	0.0e+00	472	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
643463684	307	41.53	8	307	13	313	5.0e-75	274	COG3965	Predicted Co/Zn/Cd cation transporter, cation efflux family	314
643463685	241	33.49	17	227	3	205	2.0e-40	159	COG0288	Carbonic anhydrase	207
643463687	321	36.36	3	320	8	306	1.0e-49	190	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
643463689	141	59.82	16	127	1	111	9.0e-42	162	COG0139	Phosphoribosyl-AMP cyclohydrolase	111
643463690	213	55.56	16	212	1	195	5.0e-72	263	COG0302	GTP cyclohydrolase I	195
643463691	149	25.52	1	144	2	146	2.0e-29	121	COG0822	NifU homolog involved in Fe-S cluster formation	150
643463692	273	24.44	1	265	1	258	2.0e-19	89.6	COG3713	Outer membrane scaffolding protein for murein synthesis, MipA/OmpV family	258
643463693	293	37.39	61	285	23	251	8.0e-47	180	COG0566	tRNA G18 (ribose-2'-O)-methylase SpoU	260
643463696	753	30	528	753	31	256	4.0e-31	130	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
643463696	753	34.29	26	479	14	458	9.0e-66	245	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
643463698	148	47.66	19	146	9	136	2.0e-37	148	COG1607	Acyl-CoA hydrolase	157
643463699	134	37.1	1	123	5	127	9.0e-16	76.2	COG3755	Uncharacterized conserved protein YecT, DUF1311 family	127
643463700	112	43.36	1	111	1	111	2.0e-19	87.7	COG5447	Uncharacterized protein	115
643463701	460	26.09	7	459	4	407	2.0e-54	207	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
643463702	204	24.14	1	174	2	173	6.0e-08	51.2	COG1309	DNA-binding transcriptional regulator, AcrR family	201
643463704	519	38.6	1	507	9	518	3.0e-78	286	COG0728	Peptidoglycan biosynthesis protein MviN/MurJ, putative lipid II flippase	518
643463705	332	27.12	12	305	4	291	4.0e-23	102	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
643463706	311	28.25	34	299	9	251	7.0e-38	151	COG3394	Predicted glycoside hydrolase or deacetylase ChbG, UPF0249 family	257
643463707	254	25.77	1	249	3	262	5.0e-33	134	COG0300	Short-chain dehydrogenase	265
643463708	249	42.98	1	229	1	241	4.0e-68	251	COG3546	Mn-containing catalase (includes spore coat protein CotJC)	277
643463709	486	42.41	7	485	1	461	2.0e-129	456	COG0415	Deoxyribodipyrimidine photolyase	461
643463710	534	41.67	14	210	1	198	5.0e-51	195	COG0518	GMP synthase - Glutamine amidotransferase domain	198
643463710	534	69.14	211	534	1	315	0.0e+00	536	COG0519	GMP synthase, PP-ATPase domain/subunit	315
643463711	265	38.87	1	263	1	265	1.0e-61	230	COG0300	Short-chain dehydrogenase	265
643463712	341	56.3	1	338	4	340	8.0e-119	420	COG2130	NADPH-dependent curcumin reductase CurA	340
643463713	150	35.34	4	118	2	117	3.0e-22	97.8	COG1733	DNA-binding transcriptional regulator, HxlR family	120
643463715	244	36.9	2	242	1	251	2.0e-44	172	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
643463716	298	28.72	2	288	1	296	4.0e-28	118	COG0583	DNA-binding transcriptional regulator, LysR family	297
643463717	402	27.56	6	379	2	372	3.0e-36	146	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
643463719	259	25.77	1	251	1	256	1.0e-18	87	COG5662	Transmembrane transcriptional regulator (anti-sigma factor RsiW)	256
643463720	180	39.88	6	177	13	176	3.0e-24	104	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
643463721	114	33.65	19	113	28	128	4.0e-17	80.1	COG3794	Plastocyanin	128
643463722	313	21.84	53	300	1	252	5.0e-16	78.5	COG1409	3',5'-cyclic AMP phosphodiesterase CpdA	301
643463723	287	42.86	18	282	1	263	6.0e-63	234	COG2240	Pyridoxal/pyridoxine/pyridoxamine kinase	281
643463724	281	41.83	13	263	1	241	3.0e-58	218	COG0565	tRNA C32,U32 (ribose-2'-O)-methylase TrmJ or a related methyltransferase	242
643463725	472	22.31	55	452	43	390	1.0e-12	68.3	COG2814	Predicted arabinose efflux permease, MFS family	394
643463726	279	39.73	5	228	6	223	3.0e-58	218	COG0796	Glutamate racemase	269
643463727	128	20.42	1	124	2	138	4.0e-06	43.7	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
643463728	521	40.81	7	498	1	432	4.0e-121	428	COG1570	Exonuclease VII, large subunit	440
643463730	238	34.85	2	236	10	238	1.0e-29	123	COG5343	Anti-sigma-K factor RskA	240
643463731	182	32.76	11	181	5	177	4.0e-25	107	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
643463732	562	62.59	1	400	1	401	4.0e-124	438	COG4651	Predicted Kef-type K+ transport protein, K+/H+ antiporter domain	408
643463733	432	43.45	1	429	1	418	2.0e-87	316	COG4949	Uncharacterized membrane-anchored protein	424
643463734	299	28.81	1	293	2	292	9.0e-32	130	COG0583	DNA-binding transcriptional regulator, LysR family	297
643463736	420	38.06	1	412	1	431	8.0e-87	314	COG5368	Uncharacterized protein	451
643463737	609	47.41	14	587	21	600	0.0e+00	571	COG4178	ABC-type uncharacterized transport system, permease and ATPase components	604
643463738	713	38.39	12	407	1	385	4.0e-65	243	COG1472	Periplasmic beta-glucosidase and related glycosidases	397
643463739	214	31.6	1	204	1	206	1.0e-20	93.3	COG0625	Glutathione S-transferase	211
643463740	488	20.1	288	487	29	228	8.0e-14	72.2	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
643463742	249	36.78	4	230	2	237	2.0e-32	132	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
643463743	491	56.36	20	485	1	467	0.0e+00	650	COG0034	Glutamine phosphoribosylpyrophosphate amidotransferase	470
643463744	204	31.95	2	170	1	168	6.0e-25	107	COG1286	Uncharacterized membrane protein, required for colicin V production	182
643463745	470	55.01	1	443	1	444	0.0e+00	570	COG1066	Predicted ATP-dependent serine protease	456
643463746	498	42.98	22	490	1	435	0.0e+00	474	COG0305	Replicative DNA helicase	435
643463747	238	35.16	147	236	29	119	4.0e-13	68.7	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
643463748	146	38.62	1	145	2	145	5.0e-18	83.7	COG3238	Uncharacterized membrane protein YdcZ, DUF606 family	150
643463750	363	59.82	39	363	6	330	0.0e+00	503	COG0113	Delta-aminolevulinic acid dehydratase, porphobilinogen synthase	330
643463751	329	67.58	1	326	1	324	0.0e+00	512	COG0435	Glutathionyl-hydroquinone reductase	324
643463753	123	36.51	1	123	4	127	2.0e-19	87.6	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
643463754	469	45.56	15	448	1	430	2.0e-105	376	COG3706	Two-component response regulator, PleD family, consists of two REC domains and a diguanylate cyclase (GGDEF) domain	435
643463755	698	48.68	54	695	6	635	0.0e+00	811	COG0187	DNA gyrase/topoisomerase IV, subunit B	635
643463756	347	28.37	3	333	15	357	1.0e-65	243	COG0174	Glutamine synthetase	443
643463757	469	47.57	3	468	2	442	0.0e+00	515	COG0174	Glutamine synthetase	443
643463758	112	75	1	112	1	112	2.0e-38	150	COG0347	Nitrogen regulatory protein PII	112
643463760	286	44.33	1	281	7	285	2.0e-78	286	COG2897	3-mercaptopyruvate sulfurtransferase SseA, contains two rhodanese domains	285
643463764	236	44.1	1	219	1	228	6.0e-61	227	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
643463765	481	21.93	147	478	1	336	3.0e-27	116	COG0642	Signal transduction histidine kinase	336
643463766	372	37.54	1	282	2	286	6.0e-40	158	COG4235	Cytochrome c-type biogenesis protein CcmH/NrfG	287
643463767	166	55.1	1	145	1	147	1.0e-45	175	COG2332	Cytochrome c-type biogenesis protein CcmE	153
643463768	660	50.7	1	643	1	643	0.0e+00	590	COG1138	Cytochrome c biogenesis factor	648
643463769	158	46.05	5	156	4	153	5.0e-38	150	COG3088	Cytochrome c-type biogenesis protein CcmH/NrfF	153
643463770	229	50.51	9	205	22	217	7.0e-68	250	COG2360	Leu/Phe-tRNA-protein transferase	221
643463772	300	51.16	1	300	1	291	2.0e-94	339	COG2321	Predicted metalloprotease	295
643463773	281	47.76	73	264	1	201	2.0e-44	172	COG1573	Uracil-DNA glycosylase	202
643463774	557	29.91	11	467	1	396	8.0e-68	251	COG0644	Dehydrogenase (flavoprotein)	396
643463775	328	47.72	21	217	14	209	3.0e-57	215	COG0009	tRNA A37 threonylcarbamoyladenosine synthetase subunit TsaC/SUA5/YrdC	211
643463776	135	47.66	15	121	13	119	6.0e-30	123	COG1733	DNA-binding transcriptional regulator, HxlR family	120
643463777	204	44.72	1	198	2	198	8.0e-52	196	COG1182	FMN-dependent NADH-azoreductase	202
643463780	187	27.55	1	180	2	196	6.0e-14	70.8	COG0778	Nitroreductase	207
643463781	241	22.47	16	229	2	209	7.0e-09	54.2	COG3806	Anti-sigma factor ChrR, cupin superfamily	216
643463782	853	27.01	21	814	11	798	4.0e-110	393	COG3264	Small-conductance mechanosensitive channel	835
643463783	363	45.66	15	360	21	364	3.0e-117	415	COG1509	L-lysine 2,3-aminomutase (EF-P beta-lysylation pathway)	369
643463784	351	45.93	6	347	4	322	1.0e-104	373	COG2269	Elongation factor P--beta-lysine ligase (EF-P beta-lysylation pathway)	322
643463785	189	37.4	1	131	2	131	4.0e-31	127	COG0231	Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)	131
643463791	507	61.56	33	495	2	463	0.0e+00	673	COG1027	Aspartate ammonia-lyase	471
643463792	769	57.77	1	769	3	780	0.0e+00	935	COG2183	Transcriptional accessory protein Tex/SPT6	780
643463795	758	13.9	15	758	2	768	1.0e-12	69.2	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
643463797	313	28.52	9	313	4	288	2.0e-18	86.5	COG1276	Putative copper export protein	289
643463798	126	41.6	1	125	2	125	2.0e-21	95	COG2372	Copper-binding protein CopC (methionine-rich)	127
643463801	625	24.44	9	607	115	771	6.0e-96	345	COG4993	Glucose dehydrogenase	773
643463805	345	32.56	6	345	1	328	3.0e-34	139	COG0714	MoxR-like ATPase	329
643463812	326	28.21	30	289	84	356	1.0e-20	94.5	COG3391	DNA-binding beta-propeller fold protein YncE	381
643463814	473	28.8	166	473	87	365	5.0e-26	112	COG4585	Signal transduction histidine kinase	365
643463815	208	38.05	5	206	4	206	6.0e-30	123	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
643463816	738	42.29	551	721	6	180	7.0e-42	166	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
643463817	774	52.61	366	765	2	402	0.0e+00	468	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
643463820	355	22.78	12	343	3	324	4.0e-17	82.6	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
643463823	114	41.67	8	114	3	110	1.0e-28	118	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
643463824	405	46.25	5	401	4	412	8.0e-108	384	COG0232	dGTP triphosphohydrolase	412
643463825	598	37.16	9	597	1	577	0.0e+00	507	COG0018	Arginyl-tRNA synthetase	577
643463827	264	37.39	18	253	4	238	2.0e-40	159	COG1354	Chromatin segregation and condensation protein Rec8/ScpA/Scc1, kleisin family	248
643463828	254	45.86	32	208	5	184	2.0e-40	158	COG1386	Chromosome segregation and condensation protein ScpB	184
643463829	343	51.78	6	314	4	300	1.0e-102	366	COG0031	Cysteine synthase	300
643463830	233	41.91	2	231	1	241	4.0e-40	158	COG0580	Glycerol uptake facilitator and related aquaporins (Major Intrinsic Protein Family)	241
643463831	410	44.74	1	409	1	404	2.0e-92	333	COG0303	Molybdopterin biosynthesis enzyme	404
643463832	175	61.15	6	162	2	157	7.0e-53	200	COG0315	Molybdenum cofactor biosynthesis enzyme	157
643463833	276	52.33	5	262	1	254	5.0e-83	300	COG0134	Indole-3-glycerol phosphate synthase	254
643463834	349	52.66	1	337	1	338	6.0e-105	374	COG0547	Anthranilate phosphoribosyltransferase	338
643463835	201	59.69	1	189	1	191	3.0e-74	270	COG0512	Anthranilate/para-aminobenzoate synthase component II	191
643463836	505	45.8	21	494	2	457	0.0e+00	464	COG0147	Anthranilate/para-aminobenzoate synthases component I	462
643463838	263	44.76	10	257	2	248	1.0e-72	266	COG0149	Triosephosphate isomerase	251
643463839	123	46.15	1	75	1	78	1.0e-13	68.7	COG1314	Preprotein translocase subunit SecG	86
643463840	542	61.3	3	540	2	531	0.0e+00	851	COG0504	CTP synthase (UTP-ammonia lyase)	533
643463841	356	39	1	356	1	316	2.0e-81	296	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
643463842	153	48.59	7	146	8	149	2.0e-48	185	COG0780	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF, C-terminal domain, T-fold superfamily	149
643463843	193	25.79	4	193	10	194	3.0e-06	45.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
643463845	427	68.54	1	426	1	423	0.0e+00	652	COG0148	Enolase	423
643463846	411	21.51	34	391	44	387	4.0e-09	56.4	COG2814	Predicted arabinose efflux permease, MFS family	394
643463847	419	33.89	15	414	3	421	1.0e-51	197	COG1055	Na+/H+ antiporter NhaD or related arsenite permease	424
643463848	107	25.96	4	107	19	115	1.0e-05	41.5	COG2919	Cell division protein FtsB	117
643463849	344	48.95	14	343	11	342	9.0e-116	410	COG1071	TPP-dependent pyruvate or acetoin dehydrogenase subunit alpha	358
643463850	460	54.63	137	459	1	323	0.0e+00	480	COG0022	Pyruvate/2-oxoglutarate/acetoin dehydrogenase complex, dehydrogenase (E1) component	324
643463851	444	43.27	1	444	1	403	1.0e-96	346	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
643463852	480	48.52	1	469	1	453	0.0e+00	488	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
643463853	325	60.07	16	313	9	306	0.0e+00	483	COG0320	Lipoate synthase	306
643463854	152	40.67	1	150	1	146	6.0e-42	163	COG2867	Ribosome association toxin PasT (RatA) of the RatAB toxin-antitoxin module	146
643463855	163	49.07	1	161	1	159	1.0e-38	152	COG1546	Nicotinamide mononucleotide (NMN) deamidase PncC	162
643463856	404	41.13	10	240	4	226	8.0e-50	191	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	230
643463856	404	55.48	247	401	1	155	1.0e-56	214	COG0245	2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	159
643463857	327	43.34	1	319	2	319	2.0e-75	276	COG0042	tRNA-dihydrouridine synthase	323
643463858	381	42.51	13	378	1	363	6.0e-107	381	COG3852	Signal transduction histidine kinase, nitrogen specific	363
643463859	491	45.45	1	491	2	463	0.0e+00	504	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
643463860	755	41.29	23	732	4	708	0.0e+00	588	COG5000	Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation	712
643463861	455	45.22	1	455	3	457	0.0e+00	482	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
643463862	195	32.47	16	166	8	161	8.0e-22	97.2	COG2059	Chromate transport protein ChrA	195
643463863	179	28.32	4	172	6	178	5.0e-16	77.6	COG2059	Chromate transport protein ChrA	195
643463864	286	34.64	3	278	2	276	2.0e-57	216	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
643463865	83	61.04	3	79	1	77	2.0e-29	120	COG1923	sRNA-binding regulator protein Hfq	77
643463866	469	45.45	46	452	16	409	4.0e-114	405	COG2262	50S ribosomal subunit-associated GTPase HflX	411
643463868	217	51.56	153	216	3	66	4.0e-16	78.3	COG1278	Cold shock protein, CspA family	67
643463869	265	31.75	1	265	2	263	3.0e-41	162	COG1235	Phosphoribosyl 1,2-cyclic phosphodiesterase	269
643463870	267	50.58	1	255	2	256	5.0e-84	304	COG0084	Tat protein secretion system quality control protein TatD (DNase activity)	256
643463871	519	42.67	1	512	2	547	0.0e+00	593	COG0143	Methionyl-tRNA synthetase	558
643463873	233	44.55	14	224	2	208	7.0e-54	203	COG0125	Thymidylate kinase	208
643463874	407	40.11	16	391	16	389	1.0e-89	323	COG1686	D-alanyl-D-alanine carboxypeptidase	389
643463875	341	37.87	35	265	2	232	1.0e-40	160	COG0797	Rare lipoprotein A, peptidoglycan hydrolase digesting "naked" glycans, contains C-terminal SPOR domain	233
643463876	141	44.88	15	141	8	133	8.0e-37	145	COG3727	G:T-mismatch repair DNA endonuclease, very short patch repair protein	150
643463877	383	24.93	1	371	3	324	1.0e-38	154	COG0270	Site-specific DNA-cytosine methylase	328
643463882	169	46.67	46	164	1	119	1.0e-30	125	COG1430	Uncharacterized conserved membrane protein, UPF0127 family	126
643463883	189	45.16	120	181	6	67	7.0e-17	80.6	COG1278	Cold shock protein, CspA family	67
643463884	251	40.43	15	246	8	238	2.0e-51	195	COG0846	NAD-dependent protein deacetylase, SIR2 family	250
643463887	613	45.48	1	595	1	553	0.0e+00	636	COG2192	Predicted carbamoyl transferase, NodU family	555
643463890	149	41.33	1	149	2	146	5.0e-34	137	COG1959	DNA-binding transcriptional regulator, IscR family	150
643463891	193	46.88	1	192	1	178	1.0e-50	192	COG0563	Adenylate kinase or related kinase	178
643463892	442	52.79	13	433	9	432	8.0e-122	430	COG0201	Preprotein translocase subunit SecY	436
643463893	164	50.65	1	151	1	151	9.0e-34	136	COG0200	Ribosomal protein L15	152
643463894	65	58.49	11	63	3	55	1.0e-12	64.7	COG1841	Ribosomal protein L30/L7E	55
643463895	189	55.93	1	177	5	181	3.0e-58	218	COG0098	Ribosomal protein S5	181
643463896	120	54.92	6	120	4	125	4.0e-28	116	COG0256	Ribosomal protein L18	125
643463897	177	52.84	1	176	1	176	2.0e-57	215	COG0097	Ribosomal protein L6P/L9E	178
643463898	132	51.88	1	132	1	132	2.0e-45	174	COG0096	Ribosomal protein S8	132
643463899	101	52.46	41	101	1	61	7.0e-14	68.7	COG0199	Ribosomal protein S14	61
643463900	243	65.92	65	243	1	179	6.0e-76	277	COG0094	Ribosomal protein L5	180
643463901	105	56.6	1	104	1	104	4.0e-20	89.6	COG0198	Ribosomal protein L24	104
643463902	122	76.23	1	122	1	122	2.0e-47	181	COG0093	Ribosomal protein L14	122
643463903	81	58.11	1	74	6	79	2.0e-20	90.3	COG0186	Ribosomal protein S17	87
643463904	70	49.21	8	70	6	68	1.0e-08	51	COG0255	Ribosomal protein L29	69
643463905	137	63.31	1	137	2	140	4.0e-46	176	COG0197	Ribosomal protein L16/L10AE	146
643463906	239	60.96	12	238	1	228	9.0e-79	286	COG0092	Ribosomal protein S3	233
643463907	128	59.65	11	124	7	120	3.0e-30	123	COG0091	Ribosomal protein L22	120
643463908	92	62.5	1	88	1	88	1.0e-34	137	COG0185	Ribosomal protein S19	93
643463909	279	58.91	1	274	1	275	9.0e-109	386	COG0090	Ribosomal protein L2	275
643463910	102	56.38	11	102	1	94	1.0e-20	91.8	COG0089	Ribosomal protein L23	94
643463911	206	44.29	1	206	2	211	3.0e-51	195	COG0088	Ribosomal protein L4	214
643463912	245	52.29	2	216	1	218	1.0e-71	262	COG0087	Ribosomal protein L3	218
643463913	102	75.49	1	102	1	102	2.0e-38	150	COG0051	Ribosomal protein S10	104
643463914	396	81.06	1	396	1	394	0.0e+00	701	COG0050	Translation elongation factor EF-Tu, a GTPase	394
643463915	691	63.83	1	690	1	691	0.0e+00	964	COG0480	Translation elongation factor EF-G, a GTPase	697
643463916	156	66.89	2	149	1	148	1.0e-56	212	COG0049	Ribosomal protein S7	148
643463917	123	71.54	1	123	7	129	3.0e-46	177	COG0048	Ribosomal protein S12	129
643463918	461	56.1	1	448	1	429	0.0e+00	550	COG0172	Seryl-tRNA synthetase	429
643463919	262	46.53	11	253	8	247	1.0e-52	200	COG0805	Sec-independent protein secretion pathway component TatC	255
643463920	208	32.32	1	99	1	94	2.0e-10	59.2	COG1826	Sec-independent protein translocase protein TatA	94
643463922	140	34.78	5	137	3	138	4.0e-20	90.9	COG3187	Heat shock protein HslJ	142
643463923	367	31.34	143	350	5	213	7.0e-30	125	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
643463924	262	31.95	8	262	4	267	4.0e-39	155	COG0647	Ribonucleotide monophosphatase NagD, HAD superfamily	269
643463927	790	46.92	35	669	1	649	0.0e+00	620	COG0210	Superfamily I DNA or RNA helicase	655
643463931	180	46.93	1	179	1	157	2.0e-45	175	COG3814	Uncharacterized protein	157
643463932	269	67.16	1	269	3	268	2.0e-112	398	COG0207	Thymidylate synthase	268
643463934	168	26.67	10	141	4	137	2.0e-08	52.6	COG1247	L-amino acid N-acyltransferase YncA	169
643463935	174	40.41	5	144	2	143	2.0e-30	125	COG0262	Dihydrofolate reductase	167
643463936	368	27.18	59	353	5	286	3.0e-42	166	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
643463937	312	30.85	7	294	4	291	8.0e-38	151	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
643463938	523	41.29	25	395	2	339	1.0e-68	254	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
643463942	68	41.18	1	68	1	68	4.0e-10	56.5	COG3585	Molybdopterin-binding protein	69
643463944	868	33.67	31	853	33	910	0.0e+00	585	COG0474	Magnesium-transporting ATPase (P-type)	917
643463945	329	31.21	4	325	3	326	4.0e-51	195	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
643463946	495	19.05	282	491	32	241	6.0e-08	52.5	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
643463947	216	46.76	1	205	5	220	3.0e-58	218	COG0283	Cytidylate kinase	222
643463948	443	42.24	11	441	8	427	2.0e-110	393	COG0128	5-enolpyruvylshikimate-3-phosphate synthase	428
643463949	118	36.72	1	117	1	128	6.0e-08	49.6	COG4530	Uncharacterized protein	129
643463952	301	39.22	1	296	7	305	5.0e-51	194	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
643463953	180	36.99	23	168	7	151	9.0e-31	126	COG0783	DNA-binding ferritin-like protein (oxidative damage protectant)	156
643463954	287	36.9	98	282	40	220	1.0e-26	113	COG2979	Uncharacterized membrane protein YebE, DUF533 family	225
643463955	265	48.7	1	264	14	282	2.0e-57	216	COG5473	Uncharacterized membrane protein	290
643463957	404	48.35	40	400	41	404	3.0e-124	438	COG4553	Poly-beta-hydroxyalkanoate depolymerase	415
643463958	217	25	6	208	1	210	3.0e-19	88.7	COG0625	Glutathione S-transferase	211
643463959	151	19.66	20	135	2	118	1.0e-06	46.2	COG0662	Mannose-6-phosphate isomerase, cupin superfamily	127
643463960	447	54.93	1	446	1	441	0.0e+00	515	COG3724	Succinylarginine dihydrolase	442
643463962	1053	43.64	1	1035	1	1009	0.0e+00	895	COG0841	Multidrug efflux pump subunit AcrB	1009
643463963	414	31.75	53	407	25	368	1.0e-28	120	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
643463964	569	33.05	45	513	1	452	3.0e-61	229	COG1538	Outer membrane protein TolC	457
643463965	390	21.73	14	367	3	303	6.0e-35	142	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
643463966	247	36.02	11	244	1	215	9.0e-43	167	COG0850	Septum formation inhibitor MinC	219
643463967	271	62.27	1	271	1	272	9.0e-111	393	COG2894	Septum formation inhibitor-activating ATPase MinD	272
643463968	111	37.04	1	79	1	81	2.0e-18	84.5	COG0851	Septum formation topological specificity factor MinE	88
643463971	468	55.98	3	467	1	422	0.0e+00	617	COG0065	Homoaconitase/3-isopropylmalate dehydratase large subunit	423
643463972	133	37.68	4	131	1	131	1.0e-22	98.8	COG2764	Uncharacterized conserved protein PhnB, glyoxalase superfamily	136
643463973	145	66.67	1	117	3	114	7.0e-41	159	COG0335	Ribosomal protein L19	115
643463975	418	22.39	22	408	5	376	7.0e-15	75.4	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
643463976	175	65.29	6	175	4	173	4.0e-63	233	COG0290	Translation initiation factor IF-3	176
643463977	179	21.74	7	166	9	155	2.0e-09	55.8	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
643463978	447	43.35	4	400	1	399	4.0e-102	365	COG0793	C-terminal processing protease CtpA/Prc, contains a PDZ domain	406
643463979	457	32.23	56	449	39	420	2.0e-64	240	COG4942	Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB	420
643463980	161	51.61	37	158	5	128	6.0e-50	190	COG0229	Peptide methionine sulfoxide reductase MsrB	140
643463981	246	49.41	61	229	6	174	2.0e-56	212	COG0225	Peptide methionine sulfoxide reductase MsrA	174
643463982	160	37.74	1	159	1	155	1.0e-36	145	COG1576	23S rRNA pseudoU1915 N3-methylase RlmH	155
643463983	146	49.57	33	146	1	115	1.0e-33	135	COG0799	Ribosomal silencing factor RsfS, regulates association of 30S and 50S subunits	115
643463984	294	34.65	1	294	12	312	4.0e-35	141	COG0657	Acetyl esterase/lipase	312
643463986	112	44.09	14	106	1	93	2.0e-23	100	COG0776	Bacterial nucleoid DNA-binding protein	94
643463987	329	58.33	10	329	3	322	7.0e-114	403	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
643463988	369	47.94	5	342	2	338	2.0e-106	379	COG0416	Fatty acid/phospholipid biosynthesis enzyme	338
643463990	175	44	4	174	6	180	1.0e-31	129	COG5452	Uncharacterized protein	180
643463991	163	40.43	17	152	5	140	1.0e-24	106	COG2913	Outer membrane protein assembly factor BamE, lipoprotein component of the BamABCDE complex	147
643463992	711	71.49	1	711	4	701	0.0e+00	870	COG3808	Na+ or H+-translocating membrane pyrophosphatase	703
643463993	323	39.81	15	323	23	317	2.0e-59	222	COG0611	Thiamine monophosphate kinase	317
643463994	154	35.86	6	149	9	149	3.0e-25	107	COG0781	Transcription termination factor NusB	151
643463995	164	42.95	14	159	9	152	6.0e-29	120	COG0054	6,7-dimethyl-8-ribityllumazine synthase (Riboflavin synthase beta chain)	152
643463996	515	36.47	21	335	12	333	2.0e-59	223	COG2187	Aminoglycoside phosphotransferase family enzyme	337
643463997	485	44.49	5	485	5	467	0.0e+00	464	COG2870	ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase	467
643463998	392	32.14	5	389	1	386	5.0e-52	198	COG2942	Mannose or cellobiose epimerase, N-acyl-D-glucosamine 2-epimerase family	388
643463999	512	55.67	14	503	1	486	0.0e+00	586	COG0606	Predicted ATPase with chaperone activity	490
643464001	523	39.33	16	164	3	147	3.0e-30	126	COG0802	tRNA A37 threonylcarbamoyladenosine biosynthesis protein TsaE	149
643464001	523	41.79	172	516	3	343	7.0e-78	285	COG3178	Predicted phosphotransferase, aminoglycoside/choline kinase (APH/ChoK) family	351
643464003	400	23.66	27	284	1	262	1.0e-18	87.9	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
643464004	333	43.22	10	321	2	316	8.0e-80	290	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
643464005	347	47.52	22	339	4	322	2.0e-89	323	COG3491	Isopenicillin N synthase and related dioxygenases	322
643464006	160	45.33	10	158	6	154	9.0e-32	129	COG1522	DNA-binding transcriptional regulator, Lrp family	154
643464007	1107	69.7	13	418	1	397	0.0e+00	562	COG0458	Carbamoylphosphate synthase large subunit	400
643464008	152	51.97	1	152	1	151	9.0e-39	152	COG0782	Transcription elongation factor, GreA/GreB family	151
643464010	582	53.56	10	570	1	541	0.0e+00	558	COG0539	Ribosomal protein S1	541
643464012	110	33.02	7	109	3	107	1.0e-12	64.9	COG0607	Rhodanese-related sulfurtransferase	110
643464013	211	38.5	1	200	1	191	4.0e-38	151	COG0746	Molybdopterin-guanine dinucleotide biosynthesis protein A	192
643464015	294	34.51	8	259	1	242	1.0e-45	176	COG0647	Ribonucleotide monophosphatase NagD, HAD superfamily	269
643464016	329	47.56	18	324	9	304	6.0e-90	324	COG0196	FAD synthase	304
643464017	526	51.09	17	425	1	409	4.0e-118	418	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
643464019	574	34.92	49	535	4	457	2.0e-81	297	COG2272	Carboxylesterase type B	491
643464022	326	22.22	11	319	13	314	2.0e-23	103	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
643464023	201	29.05	11	184	1	179	9.0e-23	100	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
643464024	397	23.6	1	392	1	375	3.0e-32	133	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
643464026	248	44.34	32	241	57	266	1.0e-57	216	COG3757	Lyzozyme M1 (1,4-beta-N-acetylmuramidase), GH25 family	269
643464027	578	40.38	55	577	1	523	0.0e+00	484	COG4986	ABC-type anion transport system, duplicated permease component	523
643464028	441	47.06	12	266	1	246	1.0e-80	294	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
643464029	242	41.54	174	238	1	65	6.0e-07	48.1	COG2771	DNA-binding transcriptional regulator, CsgD family	65
643464031	470	40.72	29	469	10	449	1.0e-104	373	COG2239	Mg/Co/Ni transporter MgtE (contains CBS domain)	451
643464032	297	28.14	72	263	67	259	2.0e-22	99.7	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
643464034	244	47.22	25	239	10	211	7.0e-72	263	COG0321	Lipoate-protein ligase B	221
643464035	229	44.8	8	227	2	222	2.0e-69	255	COG1136	ABC-type lipoprotein export system, ATPase component	226
643464036	423	41.25	11	423	1	408	6.0e-98	351	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
643464037	440	41.52	1	439	1	500	0.0e+00	472	COG0442	Prolyl-tRNA synthetase	500
643464038	137	45.04	3	132	1	128	3.0e-28	117	COG3742	Uncharacterized protein, contains PIN domain	131
643464039	79	40	1	78	1	80	9.0e-06	41.8	COG4423	Uncharacterized protein	81
643464040	133	38.71	1	124	2	123	4.0e-19	87.3	COG3788	Uncharacterized membrane protein YecN, MAPEG domain	131
643464041	195	29.29	1	195	1	187	2.0e-26	112	COG2249	Putative NADPH-quinone reductase (modulator of drug activity B)	189
643464044	612	52.53	1	612	1	597	0.0e+00	760	COG0449	Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains	597
643464045	460	46.2	17	457	1	460	0.0e+00	513	COG1207	Bifunctional protein GlmU, N-acetylglucosamine-1-phosphate-uridyltransferase/glucosamine-1-phosphate-acetyltransferase	460
643464046	530	39.84	54	530	37	528	6.0e-128	451	COG3131	Periplasmic glucans biosynthesis protein	534
643464047	734	41.31	26	721	27	728	0.0e+00	668	COG2943	Membrane glycosyltransferase	736
643464048	307	16.6	1	261	3	252	4.0e-06	45.5	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
643464049	307	14.03	1	274	3	265	9.0e-07	47.8	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
643464052	899	27.92	5	882	1	737	0.0e+00	625	COG0574	Phosphoenolpyruvate synthase/pyruvate phosphate dikinase	740
643464053	642	58.68	5	635	1	625	0.0e+00	892	COG1154	Deoxyxylulose-5-phosphate synthase	627
643464054	255	52.3	19	255	4	242	2.0e-75	275	COG1189	Predicted rRNA methylase YqxC, contains S4 and FtsJ domains	245
643464055	422	31.24	5	404	4	431	1.0e-71	264	COG2265	tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family	432
643464057	376	61.92	126	364	1	239	9.0e-98	350	COG1186	Protein chain release factor B	239
643464058	234	33.33	25	225	4	200	8.0e-38	150	COG2140	Oxalate decarboxylase/archaeal phosphoglucose isomerase, cupin superfamily	209
643464063	804	50.69	4	790	1	791	0.0e+00	975	COG5009	Membrane carboxypeptidase/penicillin-binding protein	797
643464064	494	31.46	183	448	2	231	2.0e-35	144	COG0860	N-acetylmuramoyl-L-alanine amidase	231
643464065	1080	49.87	345	734	83	473	4.0e-115	410	COG1530	Ribonuclease G or E	487
643464066	260	25.7	11	253	5	244	1.0e-25	110	COG1651	Protein-disulfide isomerase	244
643464067	453	27.19	17	453	5	410	3.0e-49	189	COG2124	Cytochrome P450	411
643464070	478	41.29	18	478	1	456	2.0e-90	326	COG0277	FAD/FMN-containing dehydrogenase	459
643464075	495	53.7	13	495	1	482	0.0e+00	689	COG0064	Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit	483
643464076	493	53.21	1	489	1	474	0.0e+00	480	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
643464077	95	45.26	1	95	1	95	5.0e-20	89.1	COG0721	Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit	96
643464078	263	27.3	1	261	16	295	3.0e-12	65.8	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
643464079	232	31.82	1	228	7	246	6.0e-34	137	COG2220	L-ascorbate metabolism protein UlaG, beta-lactamase superfamily	258
643464080	161	41.73	18	155	1	139	5.0e-34	137	COG0816	RNase H-fold protein, predicted Holliday junction resolvase in Firmicutes and mycoplasms, involved in anti-termination at Rho-dependent terminators	141
643464081	494	33.05	35	494	17	461	1.0e-36	148	COG0531	Amino acid transporter	466
643464082	420	22.8	9	407	9	444	3.0e-20	93.1	COG1231	Monoamine oxidase	450
643464083	413	54.3	1	406	4	385	0.0e+00	467	COG3146	Predicted N-acyltransferase	387
643464084	145	46.38	8	142	1	138	4.0e-34	137	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
643464085	826	45.38	4	756	2	780	0.0e+00	853	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
643464086	169	50.47	63	169	1	107	8.0e-35	140	COG2127	ATP-dependent Clp protease adapter protein ClpS	107
643464088	614	38.64	81	384	40	347	2.0e-73	270	COG1686	D-alanyl-D-alanine carboxypeptidase	389
643464091	217	26.96	12	208	8	209	4.0e-22	98.4	COG0625	Glutathione S-transferase	211
643464092	229	47.16	3	229	1	229	1.0e-55	209	COG3821	Uncharacterized membrane protein	234
643464093	264	30.71	15	255	1	222	2.0e-27	116	COG1434	Uncharacterized SAM-binding protein YcdF, DUF218 family	223
643464094	73	47.54	17	73	5	64	1.0e-08	51.2	COG3024	Endogenous inhibitor of DNA gyrase, YacG/DUF329 family	65
643464095	215	50.76	11	207	1	191	1.0e-57	216	COG0424	Predicted house-cleaning NTP pyrophosphatase, Maf/HAM1 superfamily	193
643464096	72	65.28	1	72	1	72	9.0e-24	101	COG0361	Translation initiation factor IF-1	75
643464097	301	39.42	42	281	1	230	2.0e-41	162	COG1183	Phosphatidylserine synthase	234
643464099	327	27.03	7	295	1	273	1.0e-13	70.8	COG3173	Predicted  kinase, aminoglycoside phosphotransferase (APT) family	321
643464100	467	46.52	2	461	4	444	0.0e+00	533	COG1160	Predicted GTPases	444
643464101	328	34.91	4	214	6	217	7.0e-32	131	COG4649	Uncharacterized protein	221
643464102	288	34.75	16	287	10	311	1.0e-64	240	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
643464105	322	30.03	1	321	4	332	1.0e-32	133	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
643464106	286	38.74	22	274	1	253	9.0e-45	174	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
643464107	252	54.25	1	245	3	248	5.0e-84	304	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
643464108	395	37.5	19	360	1	329	2.0e-52	200	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
643464109	481	42.4	10	468	4	466	3.0e-107	382	COG4529	Uncharacterized NAD(P)/FAD-binding protein YdhS	474
643464110	302	44.36	42	298	2	258	1.0e-57	216	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
643464111	262	49.37	34	262	8	244	1.0e-74	272	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
643464112	316	34.27	4	311	3	320	1.0e-39	157	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
643464115	449	45.36	1	449	5	464	3.0e-116	412	COG1109	Phosphomannomutase	464
643464117	377	35.24	50	270	23	241	4.0e-32	132	COG0037	tRNA(Ile)-lysidine synthase TilS/MesJ	298
643464118	643	57.95	9	605	1	596	0.0e+00	756	COG0465	ATP-dependent Zn proteases	596
643464120	380	31.4	86	378	10	259	6.0e-38	152	COG1237	Metal-dependent hydrolase, beta-lactamase superfamily II	259
643464121	169	36.3	19	164	42	187	2.0e-30	124	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
643464123	333	42.2	16	333	7	326	4.0e-62	231	COG0714	MoxR-like ATPase	329
643464124	242	56.84	53	240	16	205	2.0e-54	205	COG3816	Uncharacterized protein	205
643464127	419	29.54	23	414	9	411	6.0e-49	188	COG0617	tRNA nucleotidyltransferase/poly(A) polymerase	412
643464129	258	37.8	5	247	2	250	5.0e-33	134	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
643464130	190	30.34	5	176	4	181	5.0e-26	111	COG3038	Cytochrome b561	181
643464131	95	69.15	1	94	1	94	4.0e-34	136	COG0234	Co-chaperonin GroES (HSP10)	96
643464132	547	48	1	535	1	524	0.0e+00	496	COG0459	Chaperonin GroEL (HSP60 family)	524
643464133	118	45.74	17	110	1	93	7.0e-20	89.4	COG0776	Bacterial nucleoid DNA-binding protein	94
643464136	701	39.41	135	701	35	602	0.0e+00	505	COG4178	ABC-type uncharacterized transport system, permease and ATPase components	604
643464137	224	32.21	12	209	6	213	3.0e-20	92.2	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
643464140	325	34.17	3	242	1	221	2.0e-42	166	COG0040	ATP phosphoribosyltransferase	290
643464141	371	35.34	8	363	24	380	1.0e-37	150	COG3705	ATP phosphoribosyltransferase regulatory subunit HisZ	390
643464142	501	34.39	10	479	1	429	8.0e-100	358	COG0124	Histidyl-tRNA synthetase	429
643464143	266	32.08	1	264	1	232	7.0e-30	124	COG3416	Uncharacterized protein	233
643464144	413	18.6	51	413	14	377	2.0e-07	50.8	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
643464145	448	40.93	1	444	28	476	6.0e-110	391	COG0513	Superfamily II DNA and RNA helicase	513
643464146	171	38.32	5	171	6	172	1.0e-35	142	COG2318	Uncharacterized damage-inducible protein DinB (forms a four-helix bundle)	172
643464147	347	22.82	14	346	10	300	1.0e-33	137	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
643464148	261	38.02	1	259	1	251	4.0e-43	168	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
643464149	167	29.37	23	165	2	141	6.0e-22	96.9	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
643464151	437	47.43	27	435	2	361	2.0e-128	452	COG0821	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase IspG/GcpE	361
643464154	225	37.91	15	224	21	226	4.0e-41	161	COG4291	Uncharacterized membrane protein	228
643464155	309	35.61	8	307	2	320	2.0e-54	206	COG0142	Geranylgeranyl pyrophosphate synthase	322
643464157	62	54.39	1	57	1	57	2.0e-13	67.6	COG0333	Ribosomal protein L32	57
643464159	330	36.98	10	316	1	238	1.0e-58	220	COG0176	Transaldolase	239
643464161	291	28.24	78	291	45	244	2.0e-11	63.2	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
643464162	153	42.45	1	139	1	137	7.0e-34	136	COG0848	Biopolymer transport protein ExbD	137
643464163	348	38.89	120	329	1	216	2.0e-40	160	COG0811	Biopolymer transport protein ExbB/TolQ	216
643464164	541	28.25	40	499	13	485	1.0e-104	374	COG0069	Glutamate synthase domain 2	485
643464167	325	40.45	20	324	3	283	9.0e-77	280	COG1281	Redox-regulated molecular chaperone, HSP33 family	286
643464168	317	52.44	13	313	7	310	2.0e-115	408	COG0078	Ornithine carbamoyltransferase	310
643464169	400	54.01	5	388	17	399	0.0e+00	500	COG4992	Acetylornithine/succinyldiaminopimelate/putrescine aminotransferase	404
643464170	220	37.21	1	215	1	169	2.0e-30	125	COG5352	Uncharacterized protein	169
643464171	265	51.97	28	252	1	227	9.0e-63	233	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
643464172	236	42.67	4	234	8	239	9.0e-42	163	COG0704	Phosphate uptake regulator	240
643464173	260	67.74	13	260	7	253	1.0e-122	432	COG1117	ABC-type phosphate transport system, ATPase component	253
643464174	279	48.25	1	279	6	291	1.0e-62	233	COG0581	ABC-type phosphate transport system, permease component	292
643464175	329	49.84	17	326	7	309	8.0e-76	277	COG0573	ABC-type phosphate transport system, permease component	310
643464176	347	37.5	4	323	13	315	8.0e-54	204	COG0226	ABC-type phosphate transport system, periplasmic component	318
643464177	363	31.64	7	352	102	447	2.0e-50	193	COG5002	Signal transduction histidine kinase	459
643464178	339	26.86	22	326	14	322	3.0e-18	86.3	COG0392	Uncharacterized membrane protein YbhN, UPF0104 family	322
643464180	300	32.64	7	290	1	280	1.0e-41	163	COG1408	Predicted phosphohydrolase, MPP superfamily	284
643464181	309	45.05	1	308	2	311	3.0e-80	291	COG0123	Acetoin utilization deacetylase AcuC or a related deacetylase	340
643464182	429	30.23	274	429	1	171	8.0e-22	98.4	COG0807	GTP cyclohydrolase II	193
643464182	429	57.35	71	274	1	203	2.0e-74	273	COG0108	3,4-dihydroxy-2-butanone 4-phosphate synthase	203
643464183	371	59.07	2	360	1	355	0.0e+00	519	COG0082	Chorismate synthase	369
643464184	158	57.52	5	157	1	151	2.0e-50	191	COG0691	tmRNA-binding protein	153
643464185	298	51.54	7	295	5	297	6.0e-91	327	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
643464186	747	30.3	446	739	2	292	1.0e-18	88.7	COG0741	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)	296
643464188	308	23.62	20	284	1	261	3.0e-11	62.8	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
643464190	130	59.32	13	130	22	138	1.0e-33	135	COG4315	Predicted lipoprotein with conserved Yx(FWY)xxD motif (function unknown)	138
643464191	274	34.35	5	262	3	256	2.0e-25	110	COG5662	Transmembrane transcriptional regulator (anti-sigma factor RsiW)	256
643464192	175	39.87	13	164	19	176	7.0e-26	110	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
643464193	1375	35.92	247	892	1	642	1.0e-105	378	COG1020	Non-ribosomal peptide synthetase component F	642
643464195	403	22.46	21	393	11	381	1.0e-19	91	COG2814	Predicted arabinose efflux permease, MFS family	394
643464196	399	23.32	23	359	1	306	6.0e-36	145	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
643464197	233	22.41	57	230	1	154	3.0e-11	62.2	COG1225	Peroxiredoxin	157
643464198	295	29.24	1	295	1	297	7.0e-23	101	COG0583	DNA-binding transcriptional regulator, LysR family	297
643464202	259	34.62	7	259	3	244	1.0e-41	163	COG2041	Periplasmic DMSO/TMAO reductase YedYZ, molybdopterin-dependent catalytic subunit	271
643464203	288	37.44	67	277	14	217	4.0e-40	158	COG4117	Thiosulfate reductase cytochrome b subunit	221
643464205	507	28.54	37	473	29	477	6.0e-91	328	COG0069	Glutamate synthase domain 2	485
643464206	469	27.35	1	216	10	219	2.0e-20	94.2	COG0785	Cytochrome c biogenesis protein CcdA	220
643464207	202	25.68	1	172	1	182	6.0e-18	84.3	COG3145	Alkylated DNA repair dioxygenase AlkB	194
643464208	177	48.82	2	165	3	172	8.0e-62	229	COG0225	Peptide methionine sulfoxide reductase MsrA	174
643464209	219	28.72	10	197	1	186	4.0e-07	48.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
643464210	302	35.89	1	301	1	326	1.0e-42	166	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
643464211	398	27.46	41	333	48	333	3.0e-16	79.9	COG2814	Predicted arabinose efflux permease, MFS family	394
643464212	572	62.54	3	567	2	559	0.0e+00	666	COG2060	K+-transporting ATPase, A chain	560
643464214	256	27.31	34	255	37	261	3.0e-25	109	COG3971	2-keto-4-pentenoate hydratase	264
643464217	128	36.72	1	127	2	129	1.0e-23	101	COG3791	Uncharacterized conserved protein	133
643464218	205	48.97	9	202	27	220	4.0e-57	214	COG4318	Uncharacterized protein	221
643464221	147	19.78	2	92	1	91	1.0e-06	46	COG1254	Acylphosphatase	92
643464223	267	34.17	142	260	1	120	8.0e-19	87.6	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
643464227	239	26.52	2	229	1	199	1.0e-20	93.5	COG3637	Opacity protein and related surface antigens	199
643464228	254	26.67	3	241	1	199	2.0e-22	99.3	COG3637	Opacity protein and related surface antigens	199
643464229	255	27.69	2	242	1	199	4.0e-23	102	COG3637	Opacity protein and related surface antigens	199
643464230	457	35.92	23	454	1	433	5.0e-117	414	COG0621	tRNA A37 methylthiotransferase MiaB	437
643464231	579	41.87	39	354	13	341	5.0e-94	339	COG1559	Cell division protein YceG, involved in septum cleavage	342
643464232	419	56.64	1	419	2	412	0.0e+00	483	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
643464233	79	56.41	1	78	3	80	5.0e-12	62.6	COG0236	Acyl carrier protein	80
643464234	245	47.24	2	243	1	251	5.0e-46	178	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
643464235	319	50.49	6	314	5	306	5.0e-80	291	COG0331	Malonyl CoA-acyl carrier protein transacylase	310
643464237	146	45.37	2	109	1	108	3.0e-29	121	COG0360	Ribosomal protein S6	112
643464238	80	61.33	1	75	1	75	1.0e-20	91.8	COG0238	Ribosomal protein S18	75
643464240	189	49.66	1	147	1	147	5.0e-45	174	COG0359	Ribosomal protein L9	148
643464242	350	32.54	1	242	3	250	2.0e-35	143	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
643464243	481	21.62	66	481	44	439	4.0e-32	132	COG3659	Carbohydrate-selective porin OprB	439
643464250	561	47.17	74	558	13	498	0.0e+00	487	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
643464251	404	33.66	1	404	1	397	2.0e-69	256	COG1459	Type II secretory pathway, component PulF	397
643464252	172	36.3	25	160	3	148	5.0e-15	73.9	COG2165	Type II secretory pathway, pseudopilin PulG	149
643464253	153	26.49	1	150	1	151	2.0e-09	55	COG4970	Tfp pilus assembly protein FimT	181
643464256	293	18	9	284	7	300	2.0e-15	76.6	COG3156	Type II secretory pathway, component PulK	323
643464261	148	40.74	13	147	2	136	2.0e-32	131	COG0848	Biopolymer transport protein ExbD	137
643464262	248	45.62	27	241	1	216	8.0e-45	174	COG0811	Biopolymer transport protein ExbB/TolQ	216
643464263	144	37.8	13	137	7	131	3.0e-26	110	COG0824	Acyl-CoA thioesterase FadM	137
643464264	338	52.11	8	337	3	329	1.0e-97	350	COG0240	Glycerol-3-phosphate dehydrogenase	329
643464265	139	39.87	1	137	2	152	9.0e-33	132	COG2947	Predicted RNA-binding protein, contains PUA-like domain	156
643464267	373	29.56	1	350	7	363	9.0e-33	134	COG1680	CubicO group peptidase, beta-lactamase class C family	390
643464268	137	33.33	27	136	7	113	1.0e-11	62.3	COG5513	Predicted secreted protein	113
643464269	112	34.95	1	102	3	105	2.0e-16	77.7	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
643464270	468	56.67	7	460	4	420	0.0e+00	636	COG0499	S-adenosylhomocysteine hydrolase	420
643464272	141	55.15	7	141	8	143	7.0e-38	149	COG1764	Organic hydroperoxide reductase OsmC/OhrA	143
643464273	443	17.42	129	442	54	379	4.0e-09	56.6	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
643464276	380	21.68	2	365	1	364	2.0e-20	93.5	COG0795	Lipopolysaccharide export LptBFGC system, permease protein LptF	364
643464278	254	46.56	4	247	1	247	2.0e-75	275	COG1134	ABC-type polysaccharide/polyol phosphate transport system, ATPase component	249
643464279	267	29.21	1	267	4	263	1.0e-28	120	COG1682	ABC-type polysaccharide/polyol phosphate export permease	263
643464281	248	24.16	63	211	34	141	1.0e-06	46.8	COG3193	Uncharacterized conserved protein GlcG, DUF336 family	141
643464282	287	41.49	49	283	1	233	1.0e-46	180	COG0412	Dienelactone hydrolase	236
643464283	387	27.64	1	377	4	372	2.0e-24	107	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
643464284	1040	40.96	2	1011	1	1008	0.0e+00	894	COG0841	Multidrug efflux pump subunit AcrB	1009
643464285	135	32.41	14	118	4	110	1.0e-06	45.7	COG0526	Thiol-disulfide isomerase or thioredoxin	127
643464286	239	30.28	3	213	11	220	8.0e-14	71.1	COG0785	Cytochrome c biogenesis protein CcdA	220
643464290	272	39.33	13	248	1	235	9.0e-66	243	COG2908	UDP-2,3-diacylglucosamine pyrophosphatase LpxH	237
643464291	345	26.08	1	326	1	372	2.0e-28	120	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
643464292	339	42.3	40	329	33	332	1.0e-54	207	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
643464293	494	42.89	1	460	29	488	9.0e-114	404	COG0513	Superfamily II DNA and RNA helicase	513
643464294	802	16.06	2	773	9	752	2.0e-20	95.4	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
643464296	212	43.72	18	200	8	190	1.0e-53	203	COG3672	Predicted transglutaminase-like cysteine proteinase	191
643464300	382	34.08	1	358	10	349	4.0e-42	165	COG0628	Predicted PurR-regulated permease PerM	355
643464301	182	28.05	7	166	12	172	4.0e-11	61.2	COG0558	Phosphatidylglycerophosphate synthase	192
643464302	353	58.67	4	349	1	344	9.0e-127	446	COG0150	Phosphoribosylaminoimidazole (AIR) synthetase	345
643464303	218	49.5	6	205	1	200	2.0e-68	251	COG0299	Folate-dependent phosphoribosylglycinamide formyltransferase PurN	200
643464305	354	28.88	17	340	13	328	5.0e-39	155	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
643464306	314	32.92	3	309	5	322	4.0e-37	148	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
643464307	140	60.74	2	136	1	135	1.0e-51	195	COG0105	Nucleoside diphosphate kinase	135
643464308	305	30.61	1	292	1	287	5.0e-27	115	COG0583	DNA-binding transcriptional regulator, LysR family	297
643464309	178	24.43	1	175	1	174	2.0e-13	69.1	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
643464310	184	40.62	1	184	2	184	4.0e-50	190	COG0450	Alkyl hydroperoxide reductase subunit AhpC (peroxiredoxin)	194
643464311	626	43.05	1	520	3	530	0.0e+00	525	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
643464314	131	41.6	1	125	3	125	8.0e-21	92.5	COG0239	Fluoride ion exporter CrcB/FEX, affects chromosome condensation	126
643464315	426	42.62	14	425	5	404	2.0e-94	339	COG0303	Molybdopterin biosynthesis enzyme	404
643464316	182	47.24	1	160	2	161	2.0e-36	145	COG1763	Molybdopterin-guanine dinucleotide biosynthesis protein	161
643464317	80	38.57	10	78	8	77	1.0e-12	64.9	COG0425	TusA-related sulfurtransferase	78
643464321	399	30.97	4	382	4	369	1.0e-40	161	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
643464322	84	45.16	1	62	1	62	7.0e-13	65.4	COG4391	Uncharacterized conserved protein, contains Zn-finger domain	62
643464323	403	27.23	25	385	1	377	3.0e-32	133	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
643464325	189	39.77	1	170	3	171	3.0e-44	171	COG0241	Histidinol phosphatase or a related phosphatase	181
643464326	381	25.08	41	348	1	296	2.0e-27	116	COG0859	ADP-heptose:LPS heptosyltransferase	334
643464327	234	51.06	28	215	2	186	2.0e-65	242	COG0194	Guanylate kinase	191
643464328	294	43.05	3	294	2	290	4.0e-65	241	COG1561	Uncharacterized conserved protein YicC, UPF0701 family	290
643464329	310	46.94	17	309	5	298	1.0e-106	379	COG1159	GTPase Era, involved in 16S rRNA processing	298
643464330	235	41.2	1	228	2	234	7.0e-57	213	COG0571	dsRNA-specific ribonuclease	235
643464331	263	31.9	16	135	1	163	6.0e-14	71.6	COG0681	Signal peptidase I	166
643464332	145	46.56	1	131	1	127	1.0e-38	152	COG0736	Phosphopantetheinyl transferase (holo-ACP synthase)	127
643464333	259	52.7	7	247	2	242	3.0e-75	275	COG0854	Pyridoxine 5'-phosphate synthase PdxJ	243
643464334	260	40.96	59	244	45	224	2.0e-16	79.9	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
643464337	736	41.17	1	734	7	701	0.0e+00	784	COG0317	(p)ppGpp synthase/hydrolase, HD superfamily	701
643464338	129	51.35	1	72	1	74	5.0e-13	66.9	COG1758	DNA-directed RNA polymerase, subunit K/omega	74
643464339	205	44.44	5	181	6	178	3.0e-35	141	COG1432	Uncharacterized conserved protein, LabA/DUF88 family	181
643464340	228	28.17	16	228	15	202	5.0e-27	114	COG1573	Uracil-DNA glycosylase	202
643464342	282	64.98	14	270	1	257	9.0e-113	399	COG0623	Enoyl-[acyl-carrier-protein] reductase (NADH)	259
643464346	431	58.24	1	430	1	430	0.0e+00	613	COG0104	Adenylosuccinate synthase	430
643464347	76	43.59	1	76	1	75	3.0e-18	83.4	COG0254	Ribosomal protein L31	75
643464349	179	49.69	14	175	12	174	2.0e-37	148	COG5317	Uncharacterized protein	175
643464351	291	54.58	1	283	1	284	1.0e-99	356	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
643464352	189	36.73	28	171	1	146	4.0e-26	111	COG1403	5-methylcytosine-specific restriction endonuclease McrA	146
643464353	393	26.23	1	393	1	407	1.0e-55	210	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
643464354	130	52.38	2	127	1	126	4.0e-44	170	COG2967	Uncharacterized protein affecting Mg2+/Co2+ transport	126
643464355	406	46.94	11	399	6	396	4.0e-123	435	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
643464356	386	26.16	220	384	22	181	1.0e-25	111	COG0717	Deoxycytidine triphosphate deaminase	183
643464359	191	39.31	16	187	8	180	4.0e-34	138	COG3038	Cytochrome b561	181
643464360	388	33.76	8	386	15	406	1.0e-72	267	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
643464361	155	45.97	1	124	1	124	1.0e-45	175	COG0853	Aspartate 1-decarboxylase	126
643464362	394	52.41	31	383	25	368	3.0e-127	448	COG2021	Homoserine acetyltransferase	368
643464364	179	51.72	1	174	1	170	4.0e-51	193	COG0221	Inorganic pyrophosphatase	171
643464365	168	23.97	1	144	7	148	1.0e-06	46.2	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
643464371	171	27.48	27	155	11	141	5.0e-13	67.5	COG1863	Multisubunit Na+/H+ antiporter, MnhE subunit	158
643464373	107	37.78	5	92	4	93	1.0e-07	48.3	COG1320	Multisubunit Na+/H+ antiporter, MnhG subunit	113
643464375	112	32.99	10	95	7	102	3.0e-08	50.6	COG1006	Multisubunit Na+/H+ antiporter, MnhC subunit	115
643464376	497	33.13	12	487	4	480	1.0e-47	184	COG0651	Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit	504
643464377	544	26.64	1	472	2	500	2.0e-25	110	COG0651	Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit	504
643464380	405	51.45	11	383	1	377	2.0e-105	376	COG4782	Esterase/lipase superfamily enzyme	377
643464381	487	22.93	92	348	17	251	1.0e-18	88.2	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
643464382	187	61.9	1	168	3	170	3.0e-59	221	COG4803	Uncharacterized membrane protein	170
643464383	345	23.08	7	334	15	351	4.0e-24	105	COG0628	Predicted PurR-regulated permease PerM	355
643464384	346	24.16	15	341	12	298	9.0e-33	134	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
643464386	1021	28.28	5	1006	1	1006	0.0e+00	736	COG0841	Multidrug efflux pump subunit AcrB	1009
643464387	367	26.58	6	362	5	367	6.0e-22	98.7	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
643464388	350	37.7	199	318	3	121	2.0e-13	70.7	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
643464389	398	40.3	3	393	2	393	2.0e-71	263	COG0786	Na+/glutamate symporter	404
643464390	474	37.61	5	452	2	457	3.0e-76	279	COG4529	Uncharacterized NAD(P)/FAD-binding protein YdhS	474
643464392	78	46.27	9	75	7	73	5.0e-11	59.6	COG5454	Predicted secreted protein	89
643464393	195	33.88	21	194	46	228	3.0e-33	134	COG1376	Lipoprotein-anchoring transpeptidase ErfK/SrfK	232
643464394	132	49.57	14	128	4	118	7.0e-36	142	COG3536	Uncharacterized conserved protein, DUF971 family	120
643464395	347	46.39	18	347	1	322	1.0e-103	369	COG2896	Molybdenum cofactor biosynthesis enzyme MoaA	322
643464396	70	62.32	1	69	1	67	1.0e-21	94.4	COG1278	Cold shock protein, CspA family	67
643464399	315	24.44	1	266	1	305	4.0e-27	115	COG1482	Mannose-6-phosphate isomerase, class I	312
643464400	789	24.74	9	381	6	379	7.0e-26	112	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
643464401	433	35.86	207	432	80	311	5.0e-39	155	COG2152	Predicted glycosyl hydrolase, GH43/DUF377 family	314
643464403	358	33.03	134	346	1	212	2.0e-32	133	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
643464406	364	41.75	41	320	3	265	1.0e-55	210	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
643464407	294	28.63	39	293	9	267	2.0e-36	145	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
643464408	288	49.65	2	287	1	286	3.0e-81	295	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
643464409	96	40.96	1	82	1	82	6.0e-08	48.9	COG2261	Uncharacterized membrane protein YeaQ/YmgE, transglycosylase-associated protein family	82
643464411	1145	32.61	2	1113	1	1097	0.0e+00	955	COG0587	DNA polymerase III, alpha subunit	1139
643464412	488	22.12	35	443	23	350	3.0e-11	63.8	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
643464413	317	31.03	37	297	28	257	7.0e-16	78.5	COG4544	Uncharacterized conserved protein	260
643464414	286	25.09	1	275	1	200	2.0e-16	79.9	COG2039	Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase)	207
643464415	415	34.46	26	394	3	373	1.0e-55	210	COG4782	Esterase/lipase superfamily enzyme	377
643464417	263	40.23	7	253	3	256	7.0e-56	210	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
643464418	281	57.88	7	279	2	274	2.0e-68	252	COG0555	ABC-type sulfate transport system, permease component	274
643464419	292	67.96	8	291	4	287	1.0e-106	379	COG4208	ABC-type sulfate transport system, permease component	287
643464420	363	54.93	1	352	1	345	2.0e-107	382	COG1118	ABC-type sulfate/molybdate transport systems, ATPase component	345
643464421	217	31.61	13	195	15	203	1.0e-25	109	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
643464422	205	35.47	5	200	7	208	2.0e-27	116	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
643464424	302	27.39	22	245	1	241	1.0e-22	100	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
643464426	324	33.24	2	313	4	349	3.0e-53	202	COG0484	DnaJ-class molecular chaperone with C-terminal Zn finger domain	371
643464428	204	56.72	4	204	17	214	2.0e-74	272	COG0259	Pyridoxine/pyridoxamine 5'-phosphate oxidase	214
643464430	229	35.9	112	226	12	126	1.0e-16	80.5	COG5451	Predicted secreted protein	128
643464431	328	38.72	1	313	13	330	2.0e-57	216	COG3191	L-aminopeptidase/D-esterase	348
643464432	333	45	35	314	20	290	4.0e-74	271	COG3258	Cytochrome c	293
643464435	435	50.23	1	434	1	438	0.0e+00	527	COG0015	Adenylosuccinate lyase	438
643464437	183	52.22	4	183	1	179	1.0e-52	199	COG3545	Predicted esterase of the alpha/beta hydrolase fold	181
643464439	442	41.59	5	428	1	427	5.0e-119	421	COG0044	Dihydroorotase or related cyclic amidohydrolase	430
643464440	279	32.87	2	278	13	292	1.0e-49	190	COG0354	Folate-binding Fe-S cluster repair protein YgfZ, possible role in tRNA modification	305
643464441	198	54.84	8	191	1	186	6.0e-72	263	COG2818	3-methyladenine DNA glycosylase Tag	188
643464442	220	26.81	27	158	1	137	1.0e-09	56.9	COG1896	5'-deoxynucleotidase YfbR and related HD superfamily hydrolases	193
643464443	170	50.62	1	160	13	172	4.0e-40	157	COG5350	Predicted protein tyrosine phosphatase	172
643464444	85	44.29	7	76	3	72	9.0e-10	55.3	COG1722	Exonuclease VII small subunit	81
643464446	229	40.76	21	229	56	264	4.0e-59	220	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
643464449	737	45.05	8	737	1	691	0.0e+00	748	COG0751	Glycyl-tRNA synthetase, beta subunit	691
643464451	322	71.09	24	317	3	288	0.0e+00	532	COG0752	Glycyl-tRNA synthetase, alpha subunit	298
643464453	257	33.88	12	253	10	245	1.0e-47	183	COG4123	tRNA1(Val) A37 N6-methylase TrmN6	248
643464455	337	35.98	17	337	1	322	1.0e-74	273	COG0142	Geranylgeranyl pyrophosphate synthase	322
643464456	433	30.69	243	431	59	246	9.0e-29	121	COG3773	Cell wall hydrolase CwlJ, involved in spore germination	249
643464458	291	34.84	2	288	1	281	4.0e-55	208	COG1947	4-diphosphocytidyl-2C-methyl-D-erythritol kinase	289
643464459	148	26.21	5	147	10	148	4.0e-08	50.8	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
643464460	112	31.31	10	107	12	110	7.0e-08	49.4	COG0640	DNA-binding transcriptional regulator, ArsR family	110
643464463	221	41.04	9	214	8	219	2.0e-45	175	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
643464464	214	46.89	6	214	3	211	7.0e-56	210	COG0800	2-keto-3-deoxy-6-phosphogluconate aldolase	211
643464465	603	40.1	8	602	4	571	0.0e+00	592	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
643464466	490	54.02	8	488	5	483	0.0e+00	646	COG0364	Glucose-6-phosphate 1-dehydrogenase	483
643464467	491	39.37	33	459	40	485	1.0e-108	387	COG0260	Leucyl aminopeptidase	485
643464469	196	57.06	1	170	1	168	2.0e-59	221	COG0242	Peptide deformylase	168
643464470	312	46.73	1	301	7	307	3.0e-92	331	COG0223	Methionyl-tRNA formyltransferase	307
643464471	248	50.2	1	247	1	246	4.0e-83	301	COG0101	tRNA U38,U39,U40 pseudouridine synthase TruA	266
643464472	342	39.47	221	333	15	127	1.0e-16	81.1	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
643464474	261	41.91	21	260	13	247	2.0e-62	232	COG1496	Copper oxidase (laccase) domain	249
643464475	369	39.26	1	362	1	368	2.0e-85	309	COG1565	SAM-dependent methyltransferase, MidA family	370
643464476	272	41.7	1	267	2	276	1.0e-58	220	COG0682	Prolipoprotein diacylglyceryltransferase	287
643464477	88	37.5	4	83	14	93	7.0e-10	55.4	COG2960	Uncharacterized conserved protein YqiC, BMFP domain	103
643464478	166	50	1	166	1	166	1.0e-51	195	COG5465	Uncharacterized protein	166
643464479	273	45.11	12	272	4	264	2.0e-49	189	COG0345	Pyrroline-5-carboxylate reductase	266
643464482	168	29.45	10	166	4	158	1.0e-16	79.1	COG3030	Protein affecting phage T7 exclusion by the F plasmid, UPF0716 family	158
643464483	239	30.47	4	235	46	277	4.0e-34	138	COG4395	Predicted lipid-binding transport protein, Tim44 family	281
643464484	351	34.81	12	337	15	366	3.0e-62	232	COG2821	Membrane-bound lytic murein transglycosylase	373
643464485	200	32.29	10	197	1	183	6.0e-23	100	COG2840	DNA-nicking endonuclease, Smr domain	184
643464486	141	53.79	9	140	5	135	9.0e-40	155	COG3824	Predicted Zn-dependent protease, minimal metalloprotease (MMP)-like domain	136
643464487	131	34.65	1	125	6	131	4.0e-20	90.3	COG1917	Cupin domain protein related to quercetin dioxygenase	131
643464488	201	56.7	1	194	1	186	9.0e-76	276	COG0066	3-isopropylmalate dehydratase small subunit	191
643464489	299	22.26	1	297	4	266	1.0e-18	87.1	COG1235	Phosphoribosyl 1,2-cyclic phosphodiesterase	269
643464490	253	36.64	12	242	10	239	2.0e-44	172	COG5424	Pyrroloquinoline quinone (PQQ) biosynthesis protein C	242
643464492	373	27.59	1	341	9	347	8.0e-43	168	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
643464493	1171	31.92	33	711	1	637	0.0e+00	555	COG4231	TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit	640
643464494	281	39.62	14	271	1	254	2.0e-47	182	COG0134	Indole-3-glycerol phosphate synthase	254
643464495	476	66.74	2	476	4	481	0.0e+00	699	COG5310	Homospermidine synthase	481
643464497	194	36.69	21	187	1	169	1.0e-29	123	COG3153	Predicted N-acetyltransferase YhbS	171
643464498	376	33.5	1	376	12	394	2.0e-86	312	COG0019	Diaminopimelate decarboxylase	394
643464499	527	44.82	4	527	1	529	0.0e+00	499	COG3131	Periplasmic glucans biosynthesis protein	534
643464500	154	29.87	1	139	12	165	2.0e-14	71.6	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
643464502	268	42.41	6	258	2	248	1.0e-48	187	COG1402	 Creatinine amidohydrolase/Fe(II)-dependent formamide hydrolase involved in riboflavin and F420 biosynthesis	250
643464503	344	20.35	7	342	1	335	6.0e-20	91.8	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
643464504	257	47.97	15	255	6	248	7.0e-74	270	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
643464505	260	38.65	7	254	9	254	6.0e-33	134	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
643464506	335	32.72	9	330	1	305	2.0e-36	146	COG0524	Sugar or nucleoside kinase, ribokinase family	311
643464508	439	44.89	1	398	1	388	4.0e-115	408	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
643464509	337	30.32	1	333	1	311	2.0e-49	190	COG0451	Nucleoside-diphosphate-sugar epimerase	314
643464511	278	57.08	10	249	31	270	2.0e-84	305	COG2326	Polyphosphate kinase 2, PPK2 family	270
643464513	414	33.87	40	414	1	370	4.0e-29	122	COG3174	Uncharacterized membrane protein, DUF4010 family	371
643464514	601	69.93	1	601	1	602	0.0e+00	1065	COG0481	Translation elongation factor EF-4, membrane-bound GTPase	603
643464515	405	20.65	95	394	20	284	1.0e-12	67.8	COG0790	TPR repeat	292
643464518	329	39.29	21	328	1	296	7.0e-55	207	COG4973	Site-specific recombinase XerC	299
643464519	105	49.06	1	105	1	104	2.0e-17	80.5	COG5467	Uncharacterized protein	104
643464520	264	55.2	11	259	1	247	5.0e-91	327	COG0152	Phosphoribosylaminoimidazole-succinocarboxamide synthase	247
643464521	79	46.15	1	78	2	79	6.0e-21	92.2	COG1828	Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component	83
643464522	231	56.33	1	228	3	231	2.0e-86	311	COG0047	Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain	231
643464525	735	51.26	1	703	8	717	0.0e+00	880	COG0046	Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain	743
643464526	77	29.41	1	77	1	85	2.0e-14	70.4	COG0271	Stress-induced morphogen (activity unknown)	90
643464527	112	63.46	1	103	2	105	2.0e-40	157	COG0278	Glutaredoxin-related protein	105
643464528	225	35.04	84	199	11	121	2.0e-11	63	COG0526	Thiol-disulfide isomerase or thioredoxin	127
643464529	466	58.26	1	460	1	459	0.0e+00	618	COG0165	Argininosuccinate lyase	459
643464530	221	31.37	12	215	13	207	2.0e-26	112	COG0400	Predicted esterase	207
643464531	308	30.95	4	294	1	289	4.0e-34	138	COG0583	DNA-binding transcriptional regulator, LysR family	297
643464532	352	45.11	21	335	16	326	2.0e-89	322	COG0158	Fructose-1,6-bisphosphatase	326
643464533	304	51.56	1	289	1	288	7.0e-121	427	COG3954	Phosphoribulokinase	289
643464534	667	57.66	12	666	5	663	0.0e+00	916	COG0021	Transketolase	663
643464535	361	43.64	1	329	1	286	6.0e-94	337	COG0191	Fructose/tagatose bisphosphate aldolase	286
643464536	484	46.83	14	467	1	428	0.0e+00	538	COG1850	Ribulose 1,5-bisphosphate carboxylase, large subunit, or a RuBisCO-like protein	429
643464537	139	44.04	1	109	6	111	6.0e-30	123	COG4451	Ribulose bisphosphate carboxylase small subunit	127
643464539	227	60.36	1	221	1	220	1.0e-84	306	COG0036	Pentose-5-phosphate-3-epimerase	220
643464541	150	34.26	12	118	6	108	1.0e-10	59.1	COG0594	RNase P protein component	117
643464542	600	38.66	262	597	5	314	1.0e-71	265	COG0706	Membrane protein insertase Oxa1/YidC/SpoIIIJ, required for the localization of integral membrane proteins	314
643464543	226	42.44	21	225	1	200	3.0e-61	228	COG0218	GTP-binding protein EngB required for normal cell division	200
643464544	294	56.27	34	294	4	265	1.0e-85	310	COG0548	Acetylglutamate kinase	265
643464545	240	27.8	15	204	5	208	2.0e-16	79.6	COG1011	FMN phosphatase YigB, HAD superfamily	229
643464546	285	47.57	3	285	1	270	1.0e-78	286	COG2171	Tetrahydrodipicolinate N-succinyltransferase	271
643464548	290	33.33	1	89	1	86	3.0e-08	53	COG1605	Chorismate mutase	101
643464549	371	39.55	14	369	4	356	3.0e-80	292	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
643464550	318	40.56	12	296	1	279	2.0e-68	252	COG0287	Prephenate dehydrogenase	279
643464551	188	31.43	14	183	13	178	3.0e-13	68.5	COG5342	Invasion protein IalB, involved in pathogenesis	181
643464552	312	32.03	38	312	39	307	3.0e-38	152	COG3509	Poly(3-hydroxybutyrate) depolymerase	312
643464555	514	47.05	28	514	5	490	0.0e+00	559	COG1003	Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain	496
643464556	446	43.39	1	446	10	448	6.0e-129	454	COG0403	Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain	450
643464557	125	58.87	3	124	8	131	4.0e-36	143	COG0509	Glycine cleavage system H protein (lipoate-binding)	131
643464558	377	44.09	9	376	4	377	1.0e-98	353	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
643464560	439	25.32	9	399	1	390	1.0e-36	147	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
643464561	267	31.78	1	250	4	259	6.0e-34	137	COG0300	Short-chain dehydrogenase	265
643464562	148	25.9	14	146	21	159	7.0e-09	53.2	COG2030	Acyl dehydratase	159
643464564	407	41.75	5	405	3	412	2.0e-94	339	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
643464566	196	34.88	29	193	58	227	5.0e-20	91.1	COG1376	Lipoprotein-anchoring transpeptidase ErfK/SrfK	232
643464567	645	45.67	67	619	1	522	0.0e+00	665	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
643464569	211	45.07	1	210	45	257	6.0e-49	187	COG5429	Uncharacterized protein	261
643464570	215	52.6	22	213	2	185	1.0e-54	206	COG1704	Uncharacterized conserved protein	185
643464571	294	40.57	16	294	5	271	3.0e-50	192	COG1512	Uncharacterized membrane protein YgcG, contains a TPM-fold domain	271
643464572	202	40.1	3	202	6	212	9.0e-31	126	COG3762	Uncharacterized membrane protein	213
643464573	236	35.86	3	194	6	202	9.0e-27	113	COG3762	Uncharacterized membrane protein	213
643464574	405	44.01	8	335	11	343	3.0e-76	279	COG2951	Membrane-bound lytic murein transglycosylase B	343
643464576	312	41.18	31	302	17	265	5.0e-63	234	COG3741	N-formylglutamate amidohydrolase	272
643464577	185	38.64	16	185	4	178	1.0e-35	142	COG5342	Invasion protein IalB, involved in pathogenesis	181
643464578	303	30.43	47	296	16	243	5.0e-48	184	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
643464579	554	55.76	11	554	1	523	0.0e+00	579	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
643464580	316	47.4	4	310	1	304	1.0e-76	280	COG0109	Polyprenyltransferase (heme O synthase)	304
643464582	201	42.71	8	198	4	195	2.0e-50	192	COG3175	Cytochrome c oxidase assembly protein Cox11	195
643464583	286	41.01	65	280	7	209	3.0e-43	169	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
643464585	366	27.9	5	345	22	383	1.0e-35	143	COG1850	Ribulose 1,5-bisphosphate carboxylase, large subunit, or a RuBisCO-like protein	429
643464588	2684	36.56	1216	1609	35	431	4.0e-91	331	COG0001	Glutamate-1-semialdehyde aminotransferase	432
643464588	2684	38.45	8	1074	1	1055	0.0e+00	750	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
643464588	2684	40.15	1851	2497	1	642	4.0e-119	424	COG1020	Non-ribosomal peptide synthetase component F	642
643464590	125	52.85	1	122	3	125	3.0e-38	150	COG5349	Uncharacterized conserved protein, DUF983 family	126
643464591	247	43.37	1	247	1	246	9.0e-48	183	COG3346	Cytochrome oxidase assembly protein ShyY1	252
643464592	473	33.05	1	462	1	410	1.0e-95	343	COG0498	Threonine synthase	411
643464593	421	37.74	1	412	15	438	6.0e-89	321	COG0612	Predicted Zn-dependent peptidase	438
643464594	202	26.78	15	196	4	186	3.0e-23	101	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
643464596	206	46.77	6	206	1	194	2.0e-59	222	COG1678	Putative transcriptional regulator, AlgH/UPF0301 family	194
643464597	316	31.17	21	251	13	222	4.0e-28	118	COG4233	Thiol-disulfide interchange protein, contains DsbC and DsbD domains	273
643464598	161	49.09	1	161	1	165	7.0e-54	203	COG0678	Peroxiredoxin	165
643464599	153	57.89	2	150	1	152	3.0e-48	184	COG0328	Ribonuclease HI	154
643464600	321	38.34	1	318	5	327	4.0e-62	231	COG2334	Ser/Thr protein kinase RdoA involved in Cpx stress response, MazF antagonist	331
643464601	245	38.14	29	243	4	216	1.0e-51	196	COG2928	Uncharacterized membrane protein	222
643464608	350	22.58	1	89	1	93	3.0e-08	53.1	COG0633	Ferredoxin	102
643464608	350	29.78	108	331	9	217	1.0e-32	134	COG0543	NAD(P)H-flavin reductase	252
643464609	660	32.02	3	660	17	606	8.0e-100	358	COG3284	Transcriptional regulator of acetoin/glycerol metabolism	606
643464611	558	34.71	1	541	2	520	6.0e-92	332	COG0459	Chaperonin GroEL (HSP60 family)	524
643464613	158	31.25	24	149	12	138	4.0e-20	90.8	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
643464616	173	41.36	1	161	1	150	2.0e-37	148	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
643464617	939	23.03	68	939	12	730	1.0e-63	238	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
643464630	309	22.52	51	272	22	221	2.0e-09	56.5	COG2801	Transposase InsO and inactivated derivatives	232
643464636	571	35.6	45	531	1	459	3.0e-84	306	COG2272	Carboxylesterase type B	491
643464645	357	37.13	194	355	2	168	1.0e-41	164	COG0350	O6-methylguanine-DNA--protein-cysteine methyltransferase	168
643464645	357	48.62	13	191	6	184	4.0e-49	188	COG2169	Methylphosphotriester-DNA--protein-cysteine methyltransferase (N-terminal fragment of Ada), contains Zn-binding and two AraC-type DNA-binding domains	187
643464646	347	45.14	35	347	4	313	1.0e-80	293	COG0123	Acetoin utilization deacetylase AcuC or a related deacetylase	340
643464648	251	38.46	2	229	1	234	4.0e-65	241	COG1121	ABC-type Mn2+/Zn2+ transport system, ATPase component	254
643464649	290	40.74	7	275	4	268	3.0e-36	146	COG1108	ABC-type Mn2+/Zn2+ transport system, permease component	274
643464650	306	34.69	6	297	11	303	3.0e-64	238	COG0803	ABC-type Zn uptake system ZnuABC, Zn-binding component ZnuA	303
643464652	107	34.34	1	99	2	97	1.0e-19	88.5	COG2329	Heme-degrading monooxygenase HmoA and related ABM domain proteins	105
643464653	942	41.13	13	923	28	909	0.0e+00	741	COG0474	Magnesium-transporting ATPase (P-type)	917
643464654	273	21.36	39	248	31	233	8.0e-07	47.8	COG3000	Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily	271
643464655	230	34.13	10	215	1	200	1.0e-34	140	COG0461	Orotate phosphoribosyltransferase	201
643464656	354	37.43	1	354	4	331	1.0e-54	207	COG2070	NAD(P)H-dependent flavin oxidoreductase YrpB, nitropropane dioxygenase family	336
643464661	346	28.96	115	333	3	211	3.0e-24	106	COG0569	Trk K+ transport system, NAD-binding component	225
643464662	123	56.14	1	114	3	116	3.0e-40	157	COG3564	Uncharacterized conserved protein, DUF779 family	116
643464663	721	44.68	253	717	106	543	0.0e+00	470	COG2225	Malate synthase	545
643464664	430	37.82	125	429	53	353	2.0e-60	227	COG0144	16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family	355
643464665	129	36.5	1	126	1	137	1.0e-17	81.9	COG5331	Uncharacterized protein	139
643464666	496	30.91	264	483	1	169	1.0e-34	141	COG0516	IMP dehydrogenase/GMP reductase	170
643464666	496	37.29	97	208	5	116	2.0e-15	77.5	COG0517	CBS domain	117
643464667	472	19.9	1	363	8	384	3.0e-10	60.6	COG2814	Predicted arabinose efflux permease, MFS family	394
643464668	237	48.33	27	234	3	203	2.0e-65	242	COG0293	23S rRNA U2552 (ribose-2'-O)-methylase RlmE/FtsJ	205
643464670	824	28.94	30	373	2	332	4.0e-31	130	COG4249	Uncharacterized protein, contains caspase domain	380
643464671	183	24.73	3	181	28	202	2.0e-32	132	COG1573	Uracil-DNA glycosylase	202
643464672	263	25.17	1	245	2	289	2.0e-22	99.7	COG1234	Ribonuclease BN, tRNA processing enzyme	292
643464673	518	30.97	159	493	9	335	2.0e-36	147	COG0642	Signal transduction histidine kinase	336
643464674	533	28.23	37	526	9	487	5.0e-66	245	COG2939	Carboxypeptidase C (cathepsin A)	498
643464675	393	24.59	6	372	4	317	1.0e-31	131	COG0270	Site-specific DNA-cytosine methylase	328
643464676	341	46.43	9	338	1	336	3.0e-77	282	COG2038	NaMN:DMB phosphoribosyltransferase	347
643464678	263	36.9	11	261	5	241	1.0e-20	94.2	COG0368	Cobalamin synthase	246
643464679	417	30	210	417	45	264	4.0e-24	106	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
643464680	234	42.23	26	231	4	206	6.0e-47	180	COG2518	Protein-L-isoaspartate O-methyltransferase	209
643464681	110	34.38	9	104	18	113	2.0e-11	60.8	COG0599	Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family	124
643464682	205	20.43	13	198	5	188	1.0e-07	50	COG1309	DNA-binding transcriptional regulator, AcrR family	201
643464683	252	48.41	1	251	1	251	1.0e-80	293	COG0496	Broad specificity polyphosphatase and 5'/3'-nucleotidase SurE	252
643464686	157	28.97	7	151	1	124	2.0e-13	68.8	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
643464687	255	29.3	15	254	5	248	1.0e-21	96.8	COG0584	Glycerophosphoryl diester phosphodiesterase	257
643464688	393	23.23	114	357	8	240	2.0e-06	46.8	COG3591	V8-like Glu-specific endopeptidase	251
643464689	345	23.08	63	304	41	298	2.0e-23	103	COG3239	Fatty acid desaturase	343
643464691	409	45.66	37	392	31	386	1.0e-99	356	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
643464697	368	38.21	39	365	32	364	1.0e-56	213	COG0387	Ca2+/H+ antiporter	368
643464698	1147	62.57	3	1147	6	1148	0.0e+00	1782	COG1038	Pyruvate carboxylase	1149
643464700	516	40	37	514	1	479	2.0e-102	366	COG4784	Putative Zn-dependent protease	479
643464701	705	45.63	50	617	1	522	0.0e+00	549	COG1966	Carbon starvation protein CstA	575
643464702	69	52.38	7	69	5	65	1.0e-14	71.9	COG2879	Uncharacterized short protein YbdD, DUF466 family	65
643464704	418	27.11	20	406	4	385	2.0e-44	173	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
643464705	536	42.07	21	306	15	304	3.0e-70	259	COG1686	D-alanyl-D-alanine carboxypeptidase	389
643464706	408	40	32	383	1	323	2.0e-77	283	COG0523	GTPase, G3E family	323
643464707	104	43.82	2	90	6	93	5.0e-19	86.1	COG1188	Ribosomal 50S subunit-recycling heat shock protein, contains S4 domain	100
643464708	112	43.94	4	65	5	68	1.0e-08	51.7	COG1146	NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit	68
643464709	456	49.09	271	434	1	165	4.0e-48	185	COG1329	RNA polymerase-interacting regulator, CarD/CdnL/TRCF family	166
643464710	132	29.31	14	124	21	130	8.0e-14	69.3	COG0071	Molecular chaperone IbpA, HSP20 family	146
643464711	88	51.32	13	88	10	85	2.0e-18	84.2	COG5568	Uncharacterized protein	85
643464712	256	34.87	22	251	9	240	5.0e-32	131	COG0748	Putative heme iron utilization protein	245
643464713	536	57.12	13	531	9	526	0.0e+00	751	COG1866	Phosphoenolpyruvate carboxykinase, ATP-dependent	529
643464714	528	47.09	1	325	2	324	2.0e-88	320	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
643464716	304	39.39	190	288	18	116	1.0e-19	90.7	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
643464717	149	33.06	19	142	3	126	5.0e-12	63.8	COG1846	DNA-binding transcriptional regulator, MarR family	126
643464718	372	27.91	6	363	4	359	6.0e-26	112	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
643464719	391	31.38	7	383	1	365	1.0e-89	323	COG1932	Phosphoserine aminotransferase	365
643464720	416	59.06	9	409	5	401	0.0e+00	592	COG0137	Argininosuccinate synthase	403
643464722	338	40.46	5	304	1	303	7.0e-72	264	COG1984	Allophanate hydrolase subunit 2	314
643464723	242	43.84	10	226	1	219	2.0e-49	189	COG2049	Allophanate hydrolase subunit 1	223
643464724	266	50.2	13	261	4	252	9.0e-73	266	COG1540	Lactam utilization protein B (function unknown)	252
643464728	484	31.78	273	480	4	215	2.0e-36	147	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
643464729	1013	35.97	15	313	12	297	7.0e-59	222	COG0258	5'-3' exonuclease	310
643464729	1013	52.44	400	1013	1	593	0.0e+00	744	COG0749	DNA polymerase I - 3'-5' exonuclease and polymerase domains	593
643464733	715	36.21	3	244	2	240	2.0e-31	131	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
643464733	715	44.44	312	615	2	304	5.0e-83	302	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
643464734	537	56.2	1	524	1	532	0.0e+00	646	COG4172	ABC-type microcin C transport system, duplicated ATPase component YejF	534
643464735	369	43.22	125	356	47	282	8.0e-54	204	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
643464736	313	42.45	1	307	1	313	2.0e-66	246	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
643464738	140	28.78	1	139	1	130	2.0e-16	78.3	COG1487	Predicted nucleic acid-binding protein, contains PIN domain	133
643464740	282	50.19	7	275	2	264	2.0e-83	302	COG0159	Tryptophan synthase alpha chain	265
643464741	288	54.2	1	283	1	286	6.0e-107	380	COG0777	Acetyl-CoA carboxylase beta subunit	294
643464742	438	41.76	1	437	4	426	2.0e-106	379	COG0285	Folylpolyglutamate synthase/Dihydropteroate synthase	427
643464744	587	26.5	6	445	17	399	1.0e-34	141	COG2133	Glucose/arabinose dehydrogenase, beta-propeller fold	399
643464745	331	42.76	24	325	6	309	1.0e-89	322	COG2066	Glutaminase	309
643464746	302	26.57	1	279	10	294	1.0e-26	113	COG1305	Transglutaminase-like enzyme, putative cysteine protease	319
643464747	118	44.44	1	117	3	126	5.0e-27	113	COG0720	6-pyruvoyl-tetrahydropterin synthase	127
643464748	211	34.5	1	211	1	212	1.0e-40	159	COG0602	Organic radical activating enzyme	212
643464750	1151	27.89	6	1131	1	1138	0.0e+00	541	COG1074	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)	1139
643464751	1043	36.09	4	756	1	697	9.0e-101	362	COG3893	Inactivated superfamily I helicase	697
643464752	339	29.22	5	332	6	377	2.0e-27	116	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
643464753	65	43.94	1	65	3	68	7.0e-11	59.1	COG2104	Sulfur carrier protein ThiS (thiamine biosynthesis)	68
643464754	265	57.53	1	259	3	260	1.0e-96	346	COG2022	Thiamin biosynthesis thiazole synthase ThiGH, ThiG subunit	262
643464755	208	44.92	2	188	20	204	2.0e-48	185	COG0352	Thiamine monophosphate synthase	211
643464756	522	35	114	253	8	147	2.0e-23	103	COG5616	TolB amino-terminal domain (function unknown)	152
643464757	74	30.65	1	62	1	61	4.0e-08	49.5	COG1942	Phenylpyruvate tautomerase PptA, 4-oxalocrotonate tautomerase family	69
643464759	188	41.77	6	163	5	154	1.0e-36	145	COG3600	Uncharacterized phage-associated protein	154
643464761	569	44.57	21	565	16	565	1.0e-129	457	COG5360	Uncharacterized conserved protein, heparinase superfamily	566
643464762	448	38.4	109	448	1	355	5.0e-71	261	COG0144	16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family	355
643464763	98	55.74	38	98	24	84	4.0e-12	63.2	COG5508	Uncharacterized protein	84
643464764	360	51.59	1	343	3	335	5.0e-124	437	COG0016	Phenylalanyl-tRNA synthetase alpha subunit	335
643464765	604	31.28	177	562	4	384	6.0e-56	212	COG0006	Xaa-Pro aminopeptidase	384
643464767	429	58.97	1	429	1	420	0.0e+00	585	COG0766	UDP-N-acetylglucosamine enolpyruvyl transferase	421
643464771	395	48.12	80	372	5	292	3.0e-81	295	COG1533	DNA repair photolyase	297
643464772	679	45.93	61	674	5	581	0.0e+00	615	COG0322	Excinuclease UvrABC, nuclease subunit	581
643464773	198	39.39	3	198	1	191	3.0e-21	95.5	COG0558	Phosphatidylglycerophosphate synthase	192
643464774	83	34.94	1	83	2	84	4.0e-13	66.5	COG1977	Molybdopterin converting factor, small subunit	84
643464775	169	41.33	13	159	5	149	7.0e-34	136	COG0314	Molybdopterin synthase catalytic subunit	149
643464776	447	30.05	52	445	2	391	2.0e-20	94.5	COG2814	Predicted arabinose efflux permease, MFS family	394
643464779	191	43.64	12	172	5	163	2.0e-46	178	COG1871	Chemotaxis receptor (MCP) glutamine deamidase CheD	164
643464781	341	50.29	5	340	3	345	1.0e-90	326	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
643464782	300	43.59	26	295	1	266	2.0e-74	272	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
643464783	161	34.19	7	161	6	160	5.0e-33	133	COG0835	Chemotaxis signal transduction protein	165
643464784	760	38.53	1	754	3	716	0.0e+00	602	COG0643	Chemotaxis protein histidine kinase CheA	716
643464787	647	34.09	222	593	10	408	6.0e-46	179	COG0840	Methyl-accepting chemotaxis protein	408
643464792	480	27.17	14	458	9	457	1.0e-45	177	COG1538	Outer membrane protein TolC	457
643464793	1049	53.55	1	1026	2	1009	0.0e+00	1014	COG0841	Multidrug efflux pump subunit AcrB	1009
643464794	403	33.42	16	382	14	370	8.0e-33	134	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
643464795	211	26.8	14	207	4	197	5.0e-11	61.2	COG1309	DNA-binding transcriptional regulator, AcrR family	201
643464796	262	25.61	18	258	1	246	1.0e-34	140	COG1414	DNA-binding transcriptional regulator, IclR family	246
643464799	598	21.72	6	370	3	343	1.0e-28	121	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
643464800	279	28.42	8	273	1	280	2.0e-23	102	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
643464802	107	33.33	4	106	2	106	4.0e-19	86.2	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
643464803	413	26.33	16	369	4	325	1.0e-33	137	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
643464804	158	18.79	18	158	17	163	1.0e-16	79.2	COG5517	3-phenylpropionate/cinnamic acid dioxygenase, small subunit	164
643464805	407	29.34	5	384	1	391	7.0e-46	178	COG0446	NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase	415
643464806	327	28.8	203	327	3	124	5.0e-14	72.2	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
643464809	145	47.15	22	143	16	138	4.0e-16	77.2	COG3193	Uncharacterized conserved protein GlcG, DUF336 family	141
643464810	504	41.98	21	504	1	469	1.0e-128	453	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
643464811	264	44.87	1	262	2	264	5.0e-64	237	COG3971	2-keto-4-pentenoate hydratase	264
643464812	313	68.49	3	313	4	309	6.0e-114	404	COG4569	Acetaldehyde dehydrogenase (acetylating)	310
643464813	346	22.51	7	338	1	341	9.0e-51	194	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
643464814	254	37.6	8	251	11	260	3.0e-53	202	COG3971	2-keto-4-pentenoate hydratase	264
643464815	65	39.39	1	65	1	66	2.0e-07	47.2	COG1942	Phenylpyruvate tautomerase PptA, 4-oxalocrotonate tautomerase family	69
643464817	402	37.73	14	395	3	353	2.0e-61	230	COG2948	Type IV secretory pathway, VirB10 components	360
643464818	226	59.29	1	226	2	227	5.0e-82	297	COG3701	Type IV secretory pathway, TrbF components	228
643464820	242	33.47	1	241	5	249	2.0e-35	142	COG1484	DNA replication protein DnaC	254
643464826	188	23.98	11	166	8	202	3.0e-11	61.8	COG1335	Nicotinamidase-related amidase	205
643464827	249	27.38	1	248	1	252	3.0e-07	49.2	COG0730	Uncharacterized membrane protein YfcA	258
643464828	402	20	1	368	14	382	1.0e-17	84.2	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
643464830	98	35.11	1	91	6	99	1.0e-13	68.4	COG2388	Predicted acetyltransferase, GNAT superfamily	99
643464833	233	55.95	4	229	1	226	1.0e-63	236	COG2181	Nitrate reductase gamma subunit	228
643464834	235	43.26	1	178	3	176	5.0e-34	137	COG2180	Nitrate reductase assembly protein NarJ, required for insertion of molybdenum cofactor	179
643464835	504	73.85	1	498	1	501	0.0e+00	889	COG1140	Nitrate reductase beta subunit	513
643464836	1244	70.12	1	1229	1	1227	0.0e+00	2042	COG5013	Nitrate reductase alpha subunit	1227
643464837	269	26.34	34	233	1	205	3.0e-20	92.6	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
643464838	917	38.79	11	432	5	417	2.0e-87	317	COG2223	Nitrate/nitrite transporter NarK	417
643464839	184	35.63	18	183	35	206	2.0e-28	118	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
643464843	271	23.24	1	227	8	244	8.0e-27	114	COG0714	MoxR-like ATPase	329
643464844	650	35.97	12	650	4	637	1.0e-107	384	COG4548	Nitric oxide reductase activation protein	637
643464845	481	21.12	40	320	76	393	9.0e-16	78.6	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
643464845	481	30.17	359	472	38	142	2.0e-07	51.1	COG2010	Cytochrome c, mono- and diheme variants	150
643464846	266	23.29	14	266	27	313	4.0e-18	85.2	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
643464847	202	28.73	1	176	10	183	4.0e-24	104	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
643464849	231	30.05	8	220	1	213	2.0e-38	152	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
643464850	394	43.33	5	391	5	391	3.0e-61	229	COG3213	Uncharacterized protein involved in response to NO	396
643464851	472	28.21	139	454	17	328	1.0e-35	144	COG0642	Signal transduction histidine kinase	336
643464853	130	29.89	6	86	4	90	4.0e-08	50.5	COG3293	Transposase	124
643464872	445	33.92	52	277	45	267	6.0e-38	152	COG0616	Periplasmic serine protease, ClpP class	317
643464876	673	28.36	3	526	1	488	5.0e-60	226	COG0286	Type I restriction-modification system, DNA methylase subunit	489
643464877	439	16.17	1	389	1	381	2.0e-11	64.3	COG0732	Restriction endonuclease S subunit	391
643464878	347	30.5	3	337	2	318	7.0e-60	224	COG4127	Predicted restriction endonuclease, Mrr-cat superfamily	318
643464879	985	22.07	10	815	2	765	3.0e-75	277	COG0610	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases ...	962
643464883	403	20.14	109	390	27	309	8.0e-11	61.9	COG0582	Integrase	309
643464885	516	42.44	1	500	1	504	6.0e-89	321	COG3898	Uncharacterized membrane-anchored protein	531
643464888	256	45.71	10	254	10	241	1.0e-71	262	COG2227	2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase	243
643464889	411	41.79	1	409	1	447	1.0e-112	400	COG0527	Aspartokinase	447
643464890	754	51.47	12	754	5	750	0.0e+00	835	COG3605	Signal transduction protein containing GAF and PtsI domains	756
643464891	360	61.94	1	356	3	361	0.0e+00	498	COG0216	Protein chain release factor A	363
643464892	146	50.36	7	145	2	140	4.0e-29	120	COG2510	Uncharacterized membrane protein	140
643464894	195	31.64	19	194	2	174	4.0e-21	94.7	COG1881	Uncharacterized conserved protein, phosphatidylethanolamine-binding protein (PEBP) family	174
643464895	280	24.9	30	265	44	300	6.0e-23	101	COG1305	Transglutaminase-like enzyme, putative cysteine protease	319
643464896	435	49.34	37	411	3	376	2.0e-97	349	COG4782	Esterase/lipase superfamily enzyme	377
643464898	530	59.96	10	530	4	515	0.0e+00	706	COG0138	AICAR transformylase/IMP cyclohydrolase PurH	515
643464899	856	43.75	17	79	8	71	4.0e-11	63.9	COG2608	Copper chaperone CopZ	71
643464899	856	47.47	77	824	1	713	0.0e+00	672	COG2217	Cation transport ATPase	713
643464901	270	23.2	40	268	9	237	5.0e-12	65.2	COG0528	Uridylate kinase	238
643464902	277	24.9	43	271	9	237	2.0e-11	63.3	COG0528	Uridylate kinase	238
643464903	69	54.41	1	68	1	68	4.0e-11	59.9	COG3585	Molybdopterin-binding protein	69
643464904	134	29.79	7	99	1	94	1.0e-13	69.2	COG2005	DNA-binding transcriptional regulator ModE (molybdenum-dependent)	130
643464905	642	24.65	1	628	9	619	5.0e-63	235	COG1506	Dipeptidyl aminopeptidase/acylaminoacyl peptidase	620
643464906	171	52.94	17	168	6	158	2.0e-45	175	COG0801	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase	160
643464907	290	42.07	24	290	3	267	6.0e-58	217	COG0294	Dihydropteroate synthase	274
643464911	282	21.68	6	280	1	274	2.0e-12	66.6	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
643464913	601	30.28	1	598	112	771	0.0e+00	521	COG4993	Glucose dehydrogenase	773
643464916	198	27.94	2	198	1	204	9.0e-19	86.8	COG0625	Glutathione S-transferase	211
643464918	285	44.73	1	273	1	267	3.0e-75	275	COG2961	23S rRNA A2030 N6-methylase RlmJ	279
643464919	301	36.44	77	300	27	248	1.0e-36	147	COG3719	Ribonuclease I	249
643464921	470	48.95	3	331	1	331	7.0e-110	391	COG0836	Mannose-1-phosphate guanylyltransferase	333
643464921	470	49.6	343	467	2	126	9.0e-34	138	COG0662	Mannose-6-phosphate isomerase, cupin superfamily	127
643464922	208	55.68	25	206	1	185	1.0e-61	229	COG0164	Ribonuclease HII	199
643464923	379	33.33	22	300	16	297	5.0e-58	218	COG0863	DNA modification methylase	302
643464926	359	46.69	9	352	9	342	4.0e-97	348	COG1194	Adenine-specific DNA glycosylase, acts on AG and A-oxoG pairs	342
643464927	163	40.74	20	142	3	134	7.0e-28	116	COG2764	Uncharacterized conserved protein PhnB, glyoxalase superfamily	136
643464928	168	33.13	2	164	16	181	5.0e-21	93.9	COG5389	Uncharacterized protein	181
643464929	229	28.75	2	228	12	244	7.0e-24	104	COG1651	Protein-disulfide isomerase	244
643464930	130	43.64	22	130	2	111	7.0e-24	102	COG2151	Metal-sulfur cluster biosynthetic enzyme	111
643464931	448	25.6	34	440	16	412	4.0e-54	205	COG0719	Fe-S cluster assembly scaffold protein SufB	412
643464932	249	59.2	1	249	3	248	4.0e-95	340	COG0396	Fe-S cluster assembly ATPase SufC	251
643464933	490	41.5	40	488	1	412	8.0e-123	434	COG0719	Fe-S cluster assembly scaffold protein SufB	412
643464934	392	41.32	5	378	2	376	1.0e-94	340	COG1104	Cysteine sulfinate desulfinase/cysteine desulfurase or related enzyme	386
643464935	229	58.49	1	211	4	209	1.0e-75	276	COG2945	Alpha/beta superfamily hydrolase	210
643464937	370	43.88	1	366	3	370	7.0e-86	311	COG2377	1,6-Anhydro-N-acetylmuramate kinase	371
643464941	419	48.18	9	419	3	401	2.0e-122	432	COG0162	Tyrosyl-tRNA synthetase	401
643464944	161	55.63	10	160	5	155	3.0e-54	204	COG1225	Peroxiredoxin	157
643464945	195	58.54	32	195	42	205	7.0e-56	210	COG5400	Uncharacterized protein	205
643464946	283	43.54	17	282	2	269	4.0e-61	228	COG1218	3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase	276
643464947	398	53.81	18	398	2	367	0.0e+00	519	COG0505	Carbamoylphosphate synthase small subunit	368
643464948	152	49.33	1	150	1	148	6.0e-34	136	COG1610	Uncharacterized conserved protein YqeY	148
643464950	272	45.52	1	260	1	268	5.0e-67	247	COG0413	Ketopantoate hydroxymethyltransferase	268
643464951	647	35.16	2	513	1	497	3.0e-98	352	COG0358	DNA primase (bacterial type)	568
643464952	683	49.58	326	682	1	342	2.0e-98	353	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
643464954	218	30.21	20	203	5	196	9.0e-22	97	COG0778	Nitroreductase	207
643464955	365	59.14	1	364	1	371	0.0e+00	481	COG0012	Ribosome-binding ATPase YchF, GTP1/OBG family	372
643464956	148	36.96	4	139	5	140	2.0e-18	85	COG5573	Predicted nucleic acid-binding protein, contains PIN domain	142
643464957	196	50.81	1	183	2	186	2.0e-63	235	COG0193	Peptidyl-tRNA hydrolase	190
643464958	227	38.3	4	97	1	93	5.0e-19	88	COG1825	Ribosomal protein L25 (general stress protein Ctc)	93
643464959	601	31.92	32	454	22	443	6.0e-55	209	COG0038	H+/Cl- antiporter ClcA	443
643464960	299	21.65	30	249	46	242	6.0e-09	55	COG3751	Proline 4-hydroxylase (includes Rps23 Pro-64 3,4-dihydroxylase Tpa1), contains SM-20 domain	252
643464961	324	21.07	10	289	4	300	1.0e-16	80.8	COG0451	Nucleoside-diphosphate-sugar epimerase	314
643464962	298	26.94	4	295	1	297	8.0e-24	104	COG0583	DNA-binding transcriptional regulator, LysR family	297
643464963	348	66.77	7	332	3	330	0.0e+00	498	COG2255	Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit	332
643464964	797	27.72	2	796	67	868	0.0e+00	775	COG2609	Pyruvate dehydrogenase complex, dehydrogenase (E1) component	887
643464965	154	50.98	1	153	3	154	7.0e-34	136	COG1522	DNA-binding transcriptional regulator, Lrp family	154
643464966	522	22.34	12	516	10	536	3.0e-55	209	COG2303	Choline dehydrogenase or related flavoprotein	542
643464968	131	19.85	6	125	5	138	6.0e-06	43.3	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
643464969	133	34.33	3	133	2	134	2.0e-20	91.6	COG3474	Cytochrome c2	135
643464970	117	35.71	1	84	1	80	3.0e-17	80.8	COG4321	Predicted DNA-binding protein, contains Ribbon-helix-helix (RHH) domain	102
643464971	689	34.3	26	674	10	606	3.0e-116	413	COG3284	Transcriptional regulator of acetoin/glycerol metabolism	606
643464972	547	31.82	1	534	2	523	3.0e-79	289	COG0459	Chaperonin GroEL (HSP60 family)	524
643464975	351	27.67	28	346	54	408	7.0e-37	148	COG2871	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrF	410
643464978	276	24.21	1	236	8	248	7.0e-18	84.6	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
643464979	304	40.67	31	298	27	289	1.0e-49	190	COG3176	Putative hemolysin	292
643464981	241	33.58	1	238	1	265	1.0e-46	179	COG4786	Flagellar basal body rod protein FlgG	265
643464982	449	44.22	10	448	6	441	0.0e+00	476	COG1157	Flagellar biosynthesis/type III secretory pathway ATPase	441
643464983	108	58.33	1	108	2	109	2.0e-25	107	COG1742	Uncharacterized inner membrane protein YnfA, drug/metabolite transporter superfamily	109
643464984	1042	37.17	21	433	4	391	2.0e-69	257	COG0506	Proline dehydrogenase	391
643464984	1042	51.99	441	1042	10	593	0.0e+00	605	COG4230	Delta 1-pyrroline-5-carboxylate dehydrogenase	769
643464985	410	41.23	1	402	4	401	7.0e-124	437	COG4992	Acetylornithine/succinyldiaminopimelate/putrescine aminotransferase	404
643464986	174	60	14	158	10	151	2.0e-53	202	COG2983	Uncharacterized cysteine cluster protein YcgN, CxxCxxCC family	153
643464987	742	40	55	711	11	648	0.0e+00	550	COG0744	Membrane carboxypeptidase (penicillin-binding protein)	661
643464988	192	38.71	8	192	9	193	1.0e-35	143	COG5402	Uncharacterized protein	194
643464989	193	23.39	18	188	11	178	2.0e-13	69.2	COG5436	Uncharacterized membrane protein	182
643464995	494	36.67	161	459	46	334	4.0e-43	169	COG0642	Signal transduction histidine kinase	336
643464997	142	51.47	2	137	11	142	2.0e-41	161	COG2166	Sulfur transfer protein SufE, Fe-S center assembly	144
643464998	137	67.19	11	137	14	141	1.0e-51	195	COG4957	Predicted transcriptional regulator	148
643464999	710	48.98	9	695	6	681	0.0e+00	797	COG1770	Protease II	682
643465001	199	50.25	1	199	2	203	2.0e-68	251	COG0605	Superoxide dismutase	204
643465003	236	41.77	1	236	3	200	3.0e-53	201	COG1974	SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase)	201
643465004	779	21.37	43	510	2	416	3.0e-24	107	COG0658	Predicted membrane metal-binding protein	453
643465005	473	42.77	1	469	6	467	2.0e-129	456	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
643465006	429	52.35	26	429	1	390	0.0e+00	491	COG0372	Citrate synthase	390
643465007	258	49.05	1	257	1	259	5.0e-85	307	COG0708	Exonuclease III	261
643465008	282	30.53	18	275	1	258	1.0e-48	187	COG1801	Uncharacterized conserved protein YecE, DUF72 family	263
643465009	280	26.72	10	247	43	274	4.0e-12	65.5	COG0790	TPR repeat	292
643465010	159	41.07	47	157	9	120	2.0e-18	85.4	COG1321	Mn-dependent transcriptional regulator, DtxR family	154
643465011	448	45.86	26	447	1	414	4.0e-75	275	COG1914	Mn2+ and Fe2+ transporters of the NRAMP family	416
643465012	902	52.15	2	901	1	875	0.0e+00	1148	COG0525	Valyl-tRNA synthetase	877
643465013	154	27.98	15	153	61	228	1.0e-07	48.9	COG3827	Cell pole-organizing protein PopZ	231
643465014	478	27.59	26	456	23	457	2.0e-46	180	COG1538	Outer membrane protein TolC	457
643465015	230	34.65	14	214	2	197	8.0e-36	143	COG2518	Protein-L-isoaspartate O-methyltransferase	209
643465017	310	51.6	1	308	1	296	3.0e-83	302	COG0264	Translation elongation factor EF-Ts	296
643465018	349	36.52	238	349	17	130	4.0e-14	72.4	COG3743	 Predicted 5' DNA nuclease, flap endonuclease-1-like, helix-3-turn-helix (H3TH) domain	133
643465018	349	53.69	3	246	1	244	8.0e-100	357	COG0052	Ribosomal protein S2	252
643465019	495	39.83	20	471	1	459	7.0e-93	334	COG0277	FAD/FMN-containing dehydrogenase	459
643465020	433	34.44	14	373	15	344	3.0e-63	236	COG1858	Cytochrome c peroxidase	364
643465021	520	29.54	3	517	7	523	4.0e-95	342	COG3511	Phospholipase C	527
643465022	1152	46.4	12	1128	4	1119	0.0e+00	1162	COG0587	DNA polymerase III, alpha subunit	1139
643465026	253	59.41	15	253	3	240	1.0e-110	392	COG1126	ABC-type polar amino acid transport system, ATPase component	240
643465027	384	37.26	171	382	18	222	4.0e-44	172	COG0765	ABC-type amino acid transport system, permease component	222
643465028	391	51.71	11	391	18	397	9.0e-106	377	COG4597	ABC-type amino acid transport system, permease component	397
643465029	340	30.57	3	261	2	261	1.0e-29	124	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
643465030	463	38.95	1	454	14	465	7.0e-110	391	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
643465031	395	37.69	7	392	1	396	1.0e-105	376	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
643465036	558	64.57	3	558	1	554	0.0e+00	860	COG2759	Formyltetrahydrofolate synthetase	554
643465037	313	41.56	5	311	4	321	7.0e-77	280	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
643465038	396	42.64	1	386	2	383	3.0e-109	389	COG0075	Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism protein PucG	383
643465039	421	62.62	1	419	2	421	0.0e+00	515	COG2379	Glycerate-2-kinase	422
643465040	399	55.13	6	393	1	387	0.0e+00	485	COG0045	Succinyl-CoA synthetase, beta subunit	387
643465041	308	58.64	1	294	1	291	2.0e-106	379	COG0074	Succinyl-CoA synthetase, alpha subunit	293
643465042	919	37	55	919	58	910	0.0e+00	663	COG2352	Phosphoenolpyruvate carboxylase	910
643465043	325	40.78	16	324	1	281	3.0e-62	232	COG2301	Citrate lyase beta subunit	283
643465044	101	32.65	1	96	3	100	1.0e-14	71	COG1324	Uncharacterized protein involved in tolerance to divalent cations	104
643465046	127	41.38	10	125	6	118	1.0e-16	79.1	COG3080	Fumarate reductase subunit D	118
643465047	134	30	1	129	1	129	3.0e-12	64.5	COG3029	Fumarate reductase subunit C	129
643465048	258	41.7	14	248	1	232	3.0e-70	258	COG0479	Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit	234
643465049	594	48.95	1	567	2	562	0.0e+00	563	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
643465050	506	34.94	32	506	10	460	6.0e-48	185	COG0471	Di- and tricarboxylate transporter	461
643465052	162	26.47	1	159	4	155	3.0e-07	48.4	COG3915	Uncharacterized protein	155
643465055	366	50	13	358	7	346	2.0e-91	329	COG3569	DNA topoisomerase IB	354
643465056	433	46.81	3	377	2	370	5.0e-126	444	COG1415	Uncharacterized protein	373
643465057	282	46.07	1	277	1	278	5.0e-83	300	COG1273	Non-homologous end joining protein Ku, dsDNA break repair	278
643465058	271	52.03	1	271	1	266	1.0e-84	306	COG1273	Non-homologous end joining protein Ku, dsDNA break repair	278
643465059	888	31.61	74	556	1	433	7.0e-75	276	COG1793	ATP-dependent DNA ligase	444
643465059	888	50.32	583	885	1	299	5.0e-98	353	COG3285	Eukaryotic-type DNA primase	299
643465061	114	49.09	56	110	2	56	7.0e-12	62.6	COG3411	(2Fe-2S) ferredoxin	64
643465062	252	36.21	20	250	11	239	1.0e-44	173	COG5424	Pyrroloquinoline quinone (PQQ) biosynthesis protein C	242
643465063	204	32.68	1	197	1	201	3.0e-24	105	COG0625	Glutathione S-transferase	211
643465064	594	32.95	34	460	5	393	3.0e-67	250	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
643465065	773	31.32	465	722	8	253	4.0e-20	93.6	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
643465065	773	35.96	2	292	1	282	7.0e-63	235	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
643465066	378	43.22	1	378	1	392	3.0e-75	275	COG0183	Acetyl-CoA acetyltransferase	392
643465067	134	52.21	22	134	26	138	7.0e-32	129	COG4315	Predicted lipoprotein with conserved Yx(FWY)xxD motif (function unknown)	138
643465069	721	23.02	153	512	30	390	2.0e-27	118	COG3673	Uncharacterized protein, PA2063/DUF2235 family	423
643465070	126	61.86	1	118	1	117	2.0e-37	147	COG3795	Uncharacterized conserved protein	123
643465071	416	59.95	1	408	1	411	2.0e-130	459	COG4941	Predicted RNA polymerase sigma factor, contains C-terminal TPR domain	415
643465072	149	44.62	28	147	2	131	3.0e-29	120	COG2764	Uncharacterized conserved protein PhnB, glyoxalase superfamily	136
643465077	308	34.78	173	287	6	120	5.0e-21	95.3	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
643465078	233	21.74	32	231	47	236	5.0e-11	61.6	COG3904	Predicted periplasmic protein	245
643465079	309	49.3	79	291	1	212	5.0e-53	201	COG0560	Phosphoserine phosphatase	212
643465080	291	24.31	8	235	7	261	7.0e-13	68.1	COG3156	Type II secretory pathway, component PulK	323
643465082	390	32.74	8	383	2	365	3.0e-101	362	COG1932	Phosphoserine aminotransferase	365
643465083	531	47.71	1	325	2	324	1.0e-91	330	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
643465084	286	25.74	6	284	19	304	5.0e-31	128	COG2017	Galactose mutarotase or related enzyme	308
643465085	321	26.69	12	307	1	292	7.0e-24	104	COG0583	DNA-binding transcriptional regulator, LysR family	297
643465087	141	22.22	2	115	1	116	3.0e-11	61.3	COG1393	Arsenate reductase and related proteins, glutaredoxin family	117
643465090	137	37.9	10	133	6	126	3.0e-21	94.2	COG2346	Truncated hemoglobin YjbI	133
643465091	366	45.91	21	360	10	351	1.0e-58	220	COG3180	Uncharacterized membrane protein AbrB, regulator of aidB expression	352
643465092	189	24.5	4	189	1	200	9.0e-21	93.4	COG1335	Nicotinamidase-related amidase	205
643465104	369	36.71	5	367	9	363	1.0e-67	250	COG0687	Spermidine/putrescine-binding periplasmic protein	363
643465105	144	38.06	2	134	7	139	2.0e-25	108	COG3193	Uncharacterized conserved protein GlcG, DUF336 family	141
643465106	184	47.13	9	175	1	174	5.0e-48	183	COG2087	Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase	175
643465107	302	34.19	1	302	11	261	6.0e-53	201	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
643465108	647	57.95	441	635	1	195	2.0e-79	290	COG0529	Adenylylsulfate kinase or related kinase	197
643465108	647	63.74	26	447	5	426	0.0e+00	635	COG2895	Sulfate adenylyltransferase subunit 1, EFTu-like GTPase family	431
643465110	346	32.69	33	341	7	303	7.0e-42	164	COG2215	ABC-type nickel/cobalt efflux system, permease component RcnA	303
643465111	211	27.19	1	210	3	213	9.0e-23	100	COG3683	ABC-type uncharacterized transport system, periplasmic component	213
643465112	526	41.65	118	526	175	587	4.0e-102	365	COG0369	Sulfite reductase, alpha subunit (flavoprotein)	587
643465113	590	32.12	59	573	4	496	2.0e-89	323	COG0155	Sulfite reductase, beta subunit (hemoprotein)	510
643465118	471	19.31	38	470	6	423	4.0e-40	159	COG1055	Na+/H+ antiporter NhaD or related arsenite permease	424
643465119	217	35.47	4	206	3	198	8.0e-30	123	COG2095	Small neutral amino acid transporter SnatA, MarC family	203
643465120	553	39.89	1	539	1	532	3.0e-106	379	COG1283	Na+/phosphate symporter	533
643465121	240	37.13	12	237	8	232	1.0e-44	173	COG0363	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase	238
643465124	179	46.4	50	174	6	129	5.0e-35	140	COG0295	Cytidine deaminase	134
643465125	69	59.42	1	69	1	67	2.0e-23	100	COG1278	Cold shock protein, CspA family	67
643465126	178	40.36	6	170	3	160	6.0e-31	127	COG1795	Formaldehyde-activating enzyme nesessary for methanogenesis	170
643465127	208	27.32	16	197	3	195	8.0e-15	73.8	COG0778	Nitroreductase	207
643465128	330	34.85	67	326	5	248	3.0e-35	142	COG2220	L-ascorbate metabolism protein UlaG, beta-lactamase superfamily	258
643465130	456	49.47	170	452	1	262	1.0e-78	287	COG1760	L-serine deaminase	262
643465132	247	40	1	188	1	185	2.0e-36	146	COG0518	GMP synthase - Glutamine amidotransferase domain	198
643465135	281	55.51	12	281	105	376	1.0e-79	289	COG2822	Iron uptake system EfeUOB, periplasmic (or lipoprotein) component EfeO/EfeM	376
643465136	433	36.92	40	427	1	352	5.0e-74	271	COG2837	Periplasmic deferrochelatase/peroxidase EfeB	352
643465137	386	37.43	36	386	20	376	1.0e-68	254	COG2822	Iron uptake system EfeUOB, periplasmic (or lipoprotein) component EfeO/EfeM	376
643465138	283	35.81	1	264	7	302	3.0e-39	155	COG0672	High-affinity Fe2+/Pb2+ permease	383
643465139	137	30.59	36	120	21	102	3.0e-06	44.3	COG0633	Ferredoxin	102
643465140	240	47.37	13	240	1	219	3.0e-55	208	COG4340	Uncharacterized protein	226
643465142	390	41.69	40	381	16	346	9.0e-70	257	COG1566	Multidrug resistance efflux pump	352
643465145	642	35.86	10	640	11	679	0.0e+00	516	COG0480	Translation elongation factor EF-G, a GTPase	697
643465146	923	48.21	14	923	3	910	0.0e+00	994	COG2352	Phosphoenolpyruvate carboxylase	910
643465147	505	54.65	1	340	5	347	3.0e-117	416	COG1171	Threonine dehydratase	347
643465148	342	50.29	3	341	2	337	3.0e-114	405	COG1064	D-arabinose 1-dehydrogenase, Zn-dependent alcohol dehydrogenase family	339
643465149	583	45.7	141	582	14	445	1.0e-121	430	COG3243	Poly(3-hydroxyalkanoate) synthetase	445
643465150	234	29.74	39	226	20	214	1.0e-25	110	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
643465152	205	54.59	1	196	2	197	4.0e-64	237	COG4566	Two-component response regulator, FixJ family, consists of REC and HTH domains	202
643465154	345	38.07	1	343	1	348	1.0e-71	263	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
643465155	329	26.98	6	303	1	314	4.0e-32	132	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
643465157	320	42.61	16	306	3	293	5.0e-66	244	COG1230	Co/Zn/Cd efflux system component	296
643465158	451	24.66	15	451	13	450	7.0e-33	135	COG0534	Na+-driven multidrug efflux pump	455
643465159	285	30.4	1	237	1	248	1.0e-16	80.9	COG5403	Uncharacterized protein	285
643465160	460	54.55	1	460	1	456	0.0e+00	522	COG3572	Gamma-glutamylcysteine synthetase	456
643465162	66	50.77	1	65	1	65	4.0e-12	62.9	COG0291	Ribosomal protein L35	65
643465163	119	61.86	1	118	1	118	2.0e-37	147	COG0292	Ribosomal protein L20	118
643465165	810	38.45	144	809	1	650	0.0e+00	558	COG0072	Phenylalanyl-tRNA synthetase beta subunit	650
643465167	172	50	1	148	3	148	2.0e-30	125	COG4103	Uncharacterized conserved protein, tellurite resistance protein B (TerB) family	148
643465168	266	42.69	8	266	6	264	8.0e-66	243	COG0300	Short-chain dehydrogenase	265
643465169	259	38.5	9	192	1	185	4.0e-40	158	COG0518	GMP synthase - Glutamine amidotransferase domain	198
643465171	279	33.58	1	259	3	258	2.0e-40	159	COG2116	Formate/nitrite transporter FocA, FNT family	265
643465173	473	33.41	16	469	1	448	2.0e-97	349	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
643465174	314	44.16	7	312	5	300	7.0e-83	300	COG4974	Site-specific recombinase XerD	300
643465176	433	39.52	10	405	5	422	7.0e-111	394	COG0621	tRNA A37 methylthiotransferase MiaB	437
643465177	290	40.73	11	282	5	272	1.0e-68	253	COG0253	Diaminopimelate epimerase	272
643465178	241	19.08	93	241	8	152	2.0e-06	46.5	COG4978	Bacterial effector-binding domain	153
643465180	294	30	175	294	3	122	7.0e-20	91.5	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
643465181	463	20.09	4	459	6	440	9.0e-55	208	COG2610	H+/gluconate symporter or related permease	442
643465182	217	51.85	1	216	2	217	3.0e-63	234	COG1788	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit	220
643465183	222	53.27	5	216	9	222	4.0e-62	230	COG2057	Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit	225
643465186	549	45.33	45	535	3	445	3.0e-130	458	COG0166	Glucose-6-phosphate isomerase	446
643465187	506	49.25	41	505	2	403	8.0e-112	398	COG0004	Ammonia channel protein AmtB	409
643465188	112	64.29	1	112	1	112	2.0e-38	151	COG0347	Nitrogen regulatory protein PII	112
643465189	303	57.54	20	303	1	285	3.0e-101	361	COG1946	Acyl-CoA thioesterase	289
643465190	69	63.64	15	69	1	55	5.0e-15	72.9	COG2835	Uncharacterized conserved protein YbaR, Trm112 family	60
643465191	219	43.95	6	219	1	221	6.0e-46	177	COG2802	Uncharacterized protein, similar to the N-terminal domain of Lon protease	221
643465192	306	44.3	8	305	10	304	1.0e-71	263	COG3118	Negative regulator of GroEL, contains thioredoxin-like and TPR-like domains	304
643465193	335	31.52	101	335	32	284	8.0e-31	127	COG1408	Predicted phosphohydrolase, MPP superfamily	284
643465196	304	32.28	1	303	1	335	4.0e-68	251	COG0002	N-acetyl-gamma-glutamylphosphate reductase	349
643465199	159	61.24	31	159	2	130	1.0e-46	178	COG0103	Ribosomal protein S9	130
643465200	156	57.53	4	149	2	147	3.0e-55	207	COG0102	Ribosomal protein L13	148
643465201	142	19.67	3	124	2	119	2.0e-08	52	COG0662	Mannose-6-phosphate isomerase, cupin superfamily	127
643465202	147	48.53	11	146	7	140	2.0e-43	168	COG1832	Predicted CoA-binding protein	140
643465203	129	32.06	1	129	5	132	1.0e-19	88.7	COG1487	Predicted nucleic acid-binding protein, contains PIN domain	133
643465204	87	40.58	16	84	3	70	1.0e-10	57.7	COG4456	Virulence-associated protein VagC (function unknown)	74
643465205	359	41.87	25	355	6	313	8.0e-48	184	COG1612	Heme A synthase	323
643465208	318	55.07	23	315	2	283	4.0e-100	358	COG0190	5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase	283
643465210	331	18.48	39	326	11	306	3.0e-19	89.3	COG2017	Galactose mutarotase or related enzyme	308
643465211	119	31.4	6	119	42	162	3.0e-12	63.8	COG4731	Uncharacterized conserved protein, DUF2147 family	162
643465212	792	34.11	449	790	3	336	1.0e-45	178	COG0642	Signal transduction histidine kinase	336
643465213	636	24.54	12	608	36	619	4.0e-71	262	COG1506	Dipeptidyl aminopeptidase/acylaminoacyl peptidase	620
643465214	403	25.22	166	395	6	217	3.0e-24	106	COG2114	Adenylate cyclase, class 3	227
643465219	1031	32.65	4	1001	1	1008	0.0e+00	751	COG0841	Multidrug efflux pump subunit AcrB	1009
643465221	523	35.02	283	523	40	314	5.0e-41	162	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
643465222	546	22.37	30	432	10	448	2.0e-28	120	COG1032	Radical SAM superfamily enzyme YgiQ, UPF0313 family	490
643465224	155	56.29	13	154	5	154	7.0e-43	166	COG3542	Predicted sugar epimerase, cupin superfamily	162
643465225	256	28.12	1	229	12	252	3.0e-20	92.6	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
643465227	235	28.25	1	223	1	206	3.0e-26	111	COG0400	Predicted esterase	207
643465229	135	52.34	10	135	2	129	8.0e-50	189	COG0229	Peptide methionine sulfoxide reductase MsrB	140
643465231	445	34.44	63	419	76	434	1.0e-61	230	COG4325	Uncharacterized membrane protein	464
643465232	821	63.86	20	578	6	556	0.0e+00	894	COG0187	DNA gyrase/topoisomerase IV, subunit B	635
643465234	864	59.44	5	853	1	779	0.0e+00	988	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
643465236	296	41.26	11	295	1	276	3.0e-49	189	COG2890	Methylase of polypeptide chain release factors	280
643465237	650	42.09	3	644	1	621	0.0e+00	651	COG0326	Molecular chaperone, HSP90 family	623
643465239	261	45.23	25	261	17	231	2.0e-33	136	COG0670	Integral membrane protein, interacts with FtsH	233
643465240	882	40.07	22	882	3	829	0.0e+00	609	COG3127	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component	829
643465242	163	35	3	135	12	151	1.0e-06	46.2	COG2391	Uncharacterized membrane protein YedE/YeeE, contains two sulfur transport domains	198
643465244	190	29.29	1	173	3	200	5.0e-20	91	COG1335	Nicotinamidase-related amidase	205
643465245	327	33.85	7	325	12	328	2.0e-68	252	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
643465247	235	59.47	1	225	2	228	9.0e-80	289	COG4181	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component	228
643465248	198	31.03	5	182	10	212	8.0e-19	87.3	COG2755	Lysophospholipase L1 or related esterase	216
643465249	177	35.56	3	177	2	179	6.0e-31	126	COG1514	2'-5' RNA ligase	180
643465251	302	33.89	9	302	2	292	8.0e-35	140	COG0583	DNA-binding transcriptional regulator, LysR family	297
643465252	275	37.04	1	181	6	193	7.0e-36	144	COG0300	Short-chain dehydrogenase	265
643465253	465	30.04	12	464	2	411	2.0e-50	193	COG2124	Cytochrome P450	411
643465257	60	45.83	13	60	16	63	9.0e-06	41.9	COG4256	Hemin uptake protein HemP	63
643465258	302	45.83	10	296	14	298	3.0e-63	235	COG4558	ABC-type hemin transport system, periplasmic component	300
643465259	356	46.75	18	353	1	331	5.0e-55	208	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
643465260	272	44.62	5	264	1	258	1.0e-68	252	COG4559	ABC-type hemin transport system, ATPase component	259
643465261	106	36.79	1	106	2	104	2.0e-18	83.9	COG2329	Heme-degrading monooxygenase HmoA and related ABM domain proteins	105
643465262	722	18.8	2	710	3	751	8.0e-35	142	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
643465265	415	43.82	27	395	1	356	2.0e-116	412	COG0482	tRNA U34 2-thiouridine synthase MnmA/TrmU, contains the PP-loop ATPase domain	356
643465267	72	50	5	72	1	67	2.0e-10	57.7	COG5481	Uncharacterized protein	67
643465268	62	49.09	1	55	1	55	5.0e-07	46.2	COG5570	Uncharacterized protein	57
643465270	561	20	15	262	1	222	5.0e-17	82.9	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
643465275	982	31.58	1	974	1	961	0.0e+00	559	COG3587	Restriction endonuclease	985
643465287	299	58.39	2	296	9	303	7.0e-97	347	COG4227	Antirestriction protein ArdC	316
643465297	580	24.47	3	496	84	577	1.0e-59	224	COG3505	Type IV secretory pathway, VirD4 component, TraG/TraD family ATPase	596
643465305	295	23	1	294	1	307	3.0e-25	109	COG0451	Nucleoside-diphosphate-sugar epimerase	314
643465307	206	21.47	3	191	10	200	4.0e-09	55	COG1309	DNA-binding transcriptional regulator, AcrR family	201
643465311	327	34.39	10	291	5	281	3.0e-39	156	COG4757	Predicted alpha/beta hydrolase	281
643465312	206	24.74	13	206	6	199	8.0e-09	53.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
643465316	461	31.09	11	455	1	458	6.0e-76	278	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
643465318	342	27.33	5	301	1	274	4.0e-34	138	COG0388	Predicted amidohydrolase	274
643465319	370	22.1	11	362	1	339	1.0e-43	170	COG2516	Biotin synthase-related protein, radical SAM superfamily	339
643465321	323	39.02	38	321	39	323	8.0e-65	240	COG2144	Selenophosphate synthetase-related protein	324
643465322	381	26.77	1	375	1	377	2.0e-28	120	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
643465324	434	22.72	12	427	4	413	2.0e-38	153	COG2072	Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD	443
643465327	1121	31.58	562	901	1	336	3.0e-45	178	COG0642	Signal transduction histidine kinase	336
643465328	306	50.88	244	300	5	61	5.0e-12	65.4	COG2771	DNA-binding transcriptional regulator, CsgD family	65
643465329	237	47.53	3	225	2	223	3.0e-76	278	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
643465330	258	51.02	13	256	3	247	4.0e-86	311	COG4674	ABC-type uncharacterized transport system, ATPase component	249
643465331	361	34.14	9	334	6	307	5.0e-40	158	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
643465332	301	45.48	5	299	4	296	3.0e-42	165	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
643465333	405	32.41	32	382	2	362	4.0e-60	225	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
643465334	206	53.66	1	203	6	202	5.0e-67	247	COG0378	Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase	202
643465335	231	38.91	14	231	9	229	7.0e-42	163	COG0830	Urease accessory protein UreF	229
643465336	172	42.45	17	154	17	153	1.0e-24	106	COG2371	Urease accessory protein UreE	155
643465337	570	75.4	2	570	1	568	0.0e+00	1032	COG0804	Urease alpha subunit	568
643465338	104	67.96	1	103	1	103	5.0e-42	162	COG0832	Urease beta subunit	106
643465339	100	71	1	100	1	100	2.0e-40	157	COG0831	Urease gamma subunit	100
643465340	282	34.82	17	259	3	249	1.0e-42	167	COG0829	Urease accessory protein UreH	269
643465343	223	43.6	10	220	1	209	7.0e-49	187	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
643465344	771	34.27	12	770	11	740	0.0e+00	526	COG4251	Bacteriophytochrome (light-regulated signal transduction histidine kinase)	750
643465345	213	29.83	16	195	14	190	1.0e-21	97	COG3230	Heme oxygenase	196
643465347	417	40.77	121	406	1	283	5.0e-80	291	COG2230	Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases	283
643465348	265	44.44	6	256	7	258	1.0e-70	260	COG3496	Uncharacterized conserved protein, DUF1365 family	261
643465349	447	54.33	12	434	11	434	0.0e+00	492	COG2907	Predicted NAD/FAD-binding protein	447
643465350	278	26.25	2	242	30	286	5.0e-20	91.9	COG0657	Acetyl esterase/lipase	312
643465351	269	39.18	4	269	12	270	3.0e-57	215	COG3752	Steroid 5-alpha reductase family enzyme	272
643465352	133	41.86	1	129	1	128	6.0e-28	116	COG4852	Uncharacterized membrane protein	134
643465353	496	31.75	7	488	6	479	2.0e-73	270	COG1233	Phytoene dehydrogenase-related protein	487
643465354	408	43.07	1	394	1	388	3.0e-113	401	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
643465363	302	40.74	37	299	2	267	7.0e-71	260	COG1348	Nitrogenase subunit NifH, an ATPase	278
643465364	1249	37.03	168	1242	122	1250	0.0e+00	807	COG1429	Cobalamin biosynthesis protein CobN, Mg-chelatase	1388
643465365	508	22.17	12	411	36	432	2.0e-25	110	COG2710	Nitrogenase molybdenum-iron protein, alpha and beta chains	456
643465366	426	20.88	40	425	47	446	1.0e-17	84.7	COG2710	Nitrogenase molybdenum-iron protein, alpha and beta chains	456
643465368	322	22.07	102	312	19	227	8.0e-10	58	COG5012	Methanogenic corrinoid protein MtbC1	227
643465372	515	29.46	1	497	2	483	4.0e-51	196	COG1233	Phytoene dehydrogenase-related protein	487
643465373	289	33.33	1	288	4	294	4.0e-39	155	COG0142	Geranylgeranyl pyrophosphate synthase	322
643465374	377	21.89	186	360	30	221	4.0e-08	53	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
643465375	315	25.07	5	311	4	350	3.0e-22	99.3	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
643465376	329	41.33	31	294	1	269	3.0e-59	222	COG1348	Nitrogenase subunit NifH, an ATPase	278
643465378	485	18.81	14	409	39	452	3.0e-14	73.5	COG2710	Nitrogenase molybdenum-iron protein, alpha and beta chains	456
643465385	309	23.43	24	307	17	287	1.0e-20	94.2	COG0382	4-hydroxybenzoate polyprenyltransferase	289
643465387	399	30.15	5	385	2	383	1.0e-42	167	COG0644	Dehydrogenase (flavoprotein)	396
643465388	173	37.42	12	166	6	158	3.0e-24	104	COG3476	Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)	161
643465389	384	24.03	20	291	2	281	1.0e-15	77.4	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
643465391	587	37.74	326	583	18	261	2.0e-26	114	COG1240	Mg-chelatase subunit ChlD	261
643465392	341	54.43	5	329	14	340	8.0e-96	343	COG1239	Mg-chelatase subunit ChlI	423
643465393	355	29.45	38	311	7	269	2.0e-32	133	COG1562	Phytoene/squalene synthetase	288
643465398	435	50.91	4	325	3	332	5.0e-96	345	COG0460	Homoserine dehydrogenase	333
643465400	277	50.4	17	265	3	254	5.0e-93	334	COG0024	Methionine aminopeptidase	255
643465401	238	38.71	22	238	8	224	8.0e-60	223	COG2003	DNA repair protein RadC, contains a helix-hairpin-helix DNA-binding motif	224
643465402	98	61.11	9	98	1	90	4.0e-35	139	COG5425	Usg protein (tryptophan operon, function unknown)	90
643465403	360	29.26	15	260	15	282	5.0e-18	85.5	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
643465404	175	33.33	19	175	5	161	6.0e-28	116	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
643465405	305	45.9	1	304	3	297	3.0e-56	212	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
643465406	456	43.77	97	439	1	313	6.0e-52	198	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
643465407	306	46.21	6	295	2	250	3.0e-80	292	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
643465408	245	60.17	9	243	2	237	8.0e-91	326	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
643465410	372	42.27	17	369	1	362	1.0e-72	266	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
643465411	242	47.73	3	220	10	220	4.0e-29	121	COG0785	Cytochrome c biogenesis protein CcdA	220
643465412	479	17.81	3	465	15	477	7.0e-10	59	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
643465413	306	30.43	15	305	8	300	2.0e-50	193	COG2264	Ribosomal protein L11 methylase PrmA	300
643465416	162	40.67	1	150	7	156	2.0e-39	155	COG1607	Acyl-CoA hydrolase	157
643465417	400	24.07	135	359	38	274	7.0e-17	82.2	COG4974	Site-specific recombinase XerD	300
643465419	203	35.85	1	193	2	212	7.0e-27	114	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
643465424	215	35.94	1	214	4	218	5.0e-35	141	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
643465425	291	44.49	31	284	18	263	1.0e-55	210	COG5387	Chaperone required for the assembly of the mitochondrial F1-ATPase	264
643465427	165	38.67	14	162	7	151	1.0e-29	122	COG2847	Copper(I)-binding protein	151
643465429	93	44.68	1	93	1	94	2.0e-22	97.3	COG3549	Plasmid maintenance system killer protein	94
643465430	93	51.09	1	92	3	94	1.0e-23	101	COG3093	Plasmid maintenance system antidote protein VapI, contains XRE-type HTH domain	104
643465431	207	45.32	1	202	1	197	3.0e-61	228	COG0307	Riboflavin synthase alpha chain	204
643465432	370	35.45	150	368	3	216	6.0e-37	148	COG1985	Pyrimidine reductase, riboflavin biosynthesis	218
643465432	370	51.05	5	147	4	146	2.0e-46	179	COG0117	Pyrimidine deaminase domain of riboflavin biosynthesis protein RibD	146
643465433	176	59.86	1	147	1	147	1.0e-52	198	COG1327	Transcriptional regulator NrdR, contains Zn-ribbon and ATP-cone domains	156
643465434	434	67.62	15	434	1	412	0.0e+00	674	COG0112	Glycine/serine hydroxymethyltransferase	413
643465437	170	24.81	33	160	1	126	5.0e-06	44.2	COG1846	DNA-binding transcriptional regulator, MarR family	126
643465438	250	67.2	1	250	1	245	1.0e-105	375	COG4689	Acetoacetate decarboxylase	247
643465441	175	34.69	18	161	3	147	8.0e-18	83.5	COG2236	Hypoxanthine phosphoribosyltransferase	192
643465442	259	36.76	7	249	2	252	8.0e-58	217	COG1058	Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA	255
643465443	139	42.45	1	138	1	137	1.0e-37	148	COG0432	Thiamin phosphate synthase YjbQ, UPF0047 family	137
643465444	222	36.13	28	212	29	201	3.0e-35	142	COG2173	D-alanyl-D-alanine dipeptidase	211
643465445	157	29.86	19	156	8	151	5.0e-06	44	COG1714	Uncharacterized membrane protein YckC, RDD family	172
643465446	244	55.42	5	244	6	244	9.0e-84	303	COG2935	Arginyl-tRNA--protein-N-Asp/Glu arginylyltransferase	253
643465449	698	31.96	426	698	1	313	8.0e-40	159	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
643465452	750	43.68	10	748	2	742	0.0e+00	756	COG0188	DNA gyrase/topoisomerase IV, subunit A	804
643465454	355	21.79	3	266	1	263	6.0e-11	62.3	COG0451	Nucleoside-diphosphate-sugar epimerase	314
643465455	147	37.39	6	120	3	114	2.0e-19	88.5	COG1733	DNA-binding transcriptional regulator, HxlR family	120
643465456	424	41.5	5	419	4	443	0.0e+00	461	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
643465457	350	48.59	3	347	34	387	1.0e-98	353	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
643465458	223	37.27	1	220	2	216	1.0e-42	166	COG0132	Dethiobiotin synthetase	223
643465460	157	69.74	6	157	3	154	1.0e-59	222	COG3558	Uncharacterized conserved protein, nuclear transport factor 2 (NTF2) superfamily	154
643465461	248	48.86	30	248	1	217	2.0e-42	165	COG1174	ABC-type proline/glycine betaine transport system, permease component	221
643465462	312	49.68	1	307	1	307	4.0e-103	368	COG1125	ABC-type proline/glycine betaine transport system, ATPase component	309
643465463	389	39.32	156	389	1	218	2.0e-38	153	COG1174	ABC-type proline/glycine betaine transport system, permease component	221
643465464	306	35.79	5	303	11	300	5.0e-64	238	COG1732	Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)	300
643465467	330	36.65	22	300	1	266	1.0e-52	200	COG2041	Periplasmic DMSO/TMAO reductase YedYZ, molybdopterin-dependent catalytic subunit	271
643465470	295	39.68	3	244	16	259	3.0e-58	218	COG0005	Purine nucleoside phosphorylase	262
643465471	186	50.87	13	185	7	179	6.0e-46	177	COG0503	Adenine/guanine phosphoribosyltransferase or related PRPP-binding protein	179
643465474	381	24.21	25	376	38	406	5.0e-29	122	COG4553	Poly-beta-hydroxyalkanoate depolymerase	415
643465475	237	55.04	1	237	8	230	9.0e-73	266	COG0689	Ribonuclease PH	230
643465476	209	48	8	206	3	190	2.0e-55	208	COG0127	Inosine/xanthosine triphosphate pyrophosphatase, all-alpha NTP-PPase family	194
643465479	389	42.78	1	389	23	411	1.0e-108	386	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
643465480	625	45	12	191	5	184	3.0e-49	190	COG3108	Uncharacterized conserved protein YcbK, DUF882 family	185
643465481	161	59.85	12	148	14	150	1.0e-41	162	COG5321	Uncharacterized protein	164
643465482	653	25.27	25	388	17	354	1.0e-42	168	COG0628	Predicted PurR-regulated permease PerM	355
643465484	337	27.75	130	337	36	243	2.0e-34	140	COG1360	Flagellar motor protein MotB	244
643465485	484	22.19	189	484	2	289	8.0e-21	95.3	COG0382	4-hydroxybenzoate polyprenyltransferase	289
643465487	442	21.2	37	426	60	444	1.0e-30	127	COG0277	FAD/FMN-containing dehydrogenase	459
643465488	247	29	3	220	5	232	1.0e-23	103	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
643465489	310	62.06	1	310	5	314	8.0e-118	416	COG0462	Phosphoribosylpyrophosphate synthetase	314
643465500	393	23.01	1	356	4	296	4.0e-14	72.7	COG3392	Adenine-specific DNA methylase	330
643465503	373	23.66	3	370	46	421	2.0e-25	110	COG4653	Predicted phage phi-C31 gp36 major capsid-like protein	422
643465505	224	30.14	23	224	10	217	1.0e-13	70.3	COG3619	Uncharacterized membrane protein YoaK, UPF0700 family	226
643465506	384	32.8	176	361	1	186	1.0e-33	137	COG2140	Oxalate decarboxylase/archaeal phosphoglucose isomerase, cupin superfamily	209
643465507	956	34.04	147	568	4	414	7.0e-53	202	COG3903	Predicted ATPase	414
643465509	572	32.91	2	541	1	545	9.0e-118	417	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
643465510	472	41.43	5	447	4	451	5.0e-117	415	COG1271	Cytochrome bd-type quinol oxidase, subunit 1	457
643465511	335	39.53	3	329	9	346	2.0e-57	216	COG1294	Cytochrome bd-type quinol oxidase, subunit 2	346
643465513	508	25.98	72	506	33	448	7.0e-36	145	COG1538	Outer membrane protein TolC	457
643465514	671	19.08	30	612	13	606	2.0e-24	108	COG1289	Uncharacterized membrane protein YccC	674
643465515	350	31.09	12	350	14	343	2.0e-53	203	COG1566	Multidrug resistance efflux pump	352
643465519	554	32.43	36	495	9	457	2.0e-62	233	COG3378	Phage- or plasmid-associated DNA primase	517
643465523	404	20.53	101	393	10	303	4.0e-07	49.6	COG0582	Integrase	309
643465525	262	63.64	1	253	4	256	4.0e-105	374	COG0623	Enoyl-[acyl-carrier-protein] reductase (NADH)	259
643465526	407	46.73	1	406	2	412	8.0e-125	440	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
643465527	175	32.91	16	171	1	147	6.0e-32	130	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
643465528	329	34.21	38	329	1	280	3.0e-40	159	COG4395	Predicted lipid-binding transport protein, Tim44 family	281
643465529	204	22.45	3	183	2	196	5.0e-17	81.1	COG1011	FMN phosphatase YigB, HAD superfamily	229
643465530	119	44.95	6	114	2	110	1.0e-31	128	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
643465532	1176	45.99	6	1173	1	1139	0.0e+00	1297	COG1197	Transcription-repair coupling factor (superfamily II helicase)	1139
643465533	98	42.7	1	89	1	88	1.0e-18	84.9	COG2938	Succinate dehydrogenase flavin-adding protein, antitoxin component of the CptAB toxin-antitoxin module	94
643465534	118	33.33	1	100	8	109	2.0e-09	54.8	COG0640	DNA-binding transcriptional regulator, ArsR family	110
643465535	322	34.84	171	321	1	148	2.0e-19	89.7	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
643465536	159	49.68	1	153	3	151	3.0e-47	181	COG3865	Glyoxalase superfamily enzyme, possibly 3-demethylubiquinone-9 3-methyltransferase	151
643465537	540	45.37	1	534	3	530	0.0e+00	567	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
643465538	690	50.14	1	680	1	676	0.0e+00	762	COG1200	RecG-like helicase	677
643465539	405	21.24	34	397	20	389	7.0e-08	52.1	COG2814	Predicted arabinose efflux permease, MFS family	394
643465541	151	34	2	149	3	144	7.0e-31	126	COG2927	DNA polymerase III, chi subunit	144
643465542	539	44.77	26	538	7	485	0.0e+00	478	COG0260	Leucyl aminopeptidase	485
643465543	361	23.77	4	361	2	364	4.0e-39	155	COG0795	Lipopolysaccharide export LptBFGC system, permease protein LptF	364
643465544	889	23.83	45	889	6	780	1.0e-99	358	COG1452	LPS assembly outer membrane protein LptD (organic solvent tolerance protein OstA)	784
643465546	345	47.06	7	345	1	332	4.0e-95	341	COG1995	4-hydroxy-L-threonine phosphate dehydrogenase PdxA	332
643465547	288	42.48	22	285	4	258	6.0e-72	264	COG0030	16S rRNA A1518 and A1519 N6-dimethyltransferase RsmA/KsgA/DIM1 (may also have DNA glycosylase/AP lyase activity)	259
643465548	285	24.75	88	271	10	208	2.0e-13	69.9	COG2755	Lysophospholipase L1 or related esterase	216
643465549	366	31.99	7	353	27	372	4.0e-43	168	COG4645	Uncharacterized protein	410
643465550	538	36.81	227	529	11	284	1.0e-47	185	COG0063	NAD(P)H-hydrate repair enzyme Nnr, NAD(P)H-hydrate dehydratase domain	284
643465550	538	43.48	7	206	1	203	4.0e-43	169	COG0062	NAD(P)H-hydrate repair enzyme Nnr, NAD(P)H-hydrate epimerase domain	203
643465551	109	58.65	6	109	13	116	2.0e-37	147	COG3785	Heat shock protein HspQ	116
643465553	927	51.12	12	905	4	804	0.0e+00	960	COG0188	DNA gyrase/topoisomerase IV, subunit A	804
643465554	168	38.69	3	168	1	167	8.0e-33	133	COG0629	Single-stranded DNA-binding protein	167
643465555	442	48.33	15	431	2	415	1.0e-97	350	COG1301	Na+/H+-dicarboxylate symporter	415
643465556	1016	68.6	64	1007	6	935	0.0e+00	1573	COG0178	Excinuclease UvrABC ATPase subunit	935
643465557	303	32.13	31	303	24	299	5.0e-52	198	COG2813	16S rRNA G1207 methylase RsmC	300
643465558	255	35.39	10	245	2	240	1.0e-50	193	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
643465561	249	49.59	9	249	1	238	6.0e-77	280	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
643465562	525	41.3	6	525	5	512	9.0e-124	437	COG0661	Predicted unusual protein kinase regulating ubiquinone biosynthesis, AarF/ABC1/UbiB family	517
643465563	421	48.19	4	416	2	391	2.0e-102	366	COG0452	Phosphopantothenoylcysteine synthetase/decarboxylase	392
643465564	160	54.23	10	151	8	146	3.0e-46	177	COG0756	dUTPase	148
643465565	148	31.65	4	138	3	141	7.0e-15	73.5	COG1959	DNA-binding transcriptional regulator, IscR family	150
643465566	197	29.38	8	190	2	203	1.0e-15	76.5	COG0778	Nitroreductase	207
643465567	349	62.25	1	347	1	345	0.0e+00	491	COG1613	ABC-type sulfate transport system, periplasmic component	348
643465568	266	36.43	8	134	2	130	1.0e-20	93.8	COG2005	DNA-binding transcriptional regulator ModE (molybdenum-dependent)	130
643465568	266	41.79	126	192	1	67	3.0e-09	56.1	COG3585	Molybdopterin-binding protein	69
643465569	365	38.19	23	325	17	315	2.0e-58	219	COG1472	Periplasmic beta-glucosidase and related glycosidases	397
643465575	263	29.1	3	263	14	279	3.0e-50	191	COG0061	NAD kinase	281
643465577	449	22.31	74	444	49	393	2.0e-10	60.6	COG2814	Predicted arabinose efflux permease, MFS family	394
643465578	220	26.99	1	220	13	226	1.0e-11	63.8	COG2301	Citrate lyase beta subunit	283
643465586	601	28.28	20	601	140	772	2.0e-112	399	COG4993	Glucose dehydrogenase	773
643465589	412	23.87	4	394	2	386	4.0e-27	116	COG0420	DNA repair exonuclease SbcCD nuclease subunit	390
643465590	1157	22.02	330	1139	209	972	3.0e-25	111	COG4717	Uncharacterized protein YhaN	984
643465592	300	26.06	6	284	1	249	9.0e-25	107	COG1409	3',5'-cyclic AMP phosphodiesterase CpdA	301
643465593	323	27.27	74	248	3	176	4.0e-23	102	COG1633	Rubrerythrin	176
643465594	281	51.36	1	255	1	257	3.0e-91	328	COG3622	Hydroxypyruvate isomerase	260
643465595	168	40.37	6	164	4	164	3.0e-29	121	COG3153	Predicted N-acetyltransferase YhbS	171
643465597	223	43	7	211	3	209	1.0e-43	170	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
643465599	206	46.84	13	201	5	194	3.0e-53	201	COG2094	3-methyladenine DNA glycosylase Mpg	200
643465601	519	31.91	6	519	1	449	5.0e-65	242	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
643465602	274	57.04	1	268	1	266	2.0e-103	369	COG1692	Calcineurin-like phosphoesterase	266
643465603	198	36.27	6	193	3	191	9.0e-34	136	COG0212	5-formyltetrahydrofolate cyclo-ligase	191
643465604	124	36.36	1	88	1	88	3.0e-13	67.2	COG3027	Cell division protein ZapA, inhibits GTPase activity of FtsZ	105
643465606	335	63.06	2	333	1	332	0.0e+00	463	COG0057	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase	335
643465607	407	49.87	12	402	6	391	0.0e+00	473	COG0126	3-phosphoglycerate kinase	395
643465608	203	40.54	7	151	4	148	8.0e-27	113	COG3613	Nucleoside 2-deoxyribosyltransferase	172
643465612	366	52.68	13	364	1	350	9.0e-113	400	COG0026	Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)	375
643465613	181	57.05	24	179	5	158	2.0e-53	201	COG0041	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase	162
643465614	200	37.1	11	198	9	228	2.0e-30	125	COG1376	Lipoprotein-anchoring transpeptidase ErfK/SrfK	232
643465616	299	37.24	12	297	15	271	3.0e-64	238	COG0130	tRNA U55 pseudouridine synthase TruB, may also work on U342 of tmRNA	271
643465617	155	40.83	11	128	2	118	5.0e-23	100	COG0858	Ribosome-binding factor A	118
643465618	886	59.14	381	886	1	507	0.0e+00	647	COG0532	Translation initiation factor IF-2, a GTPase	509
643465619	234	42.05	15	102	2	87	6.0e-20	91.2	COG2740	Predicted RNA-binding protein YlxR, DUF448 family	95
643465620	532	56.12	161	355	1	190	6.0e-52	198	COG0195	Transcription antitermination factor NusA, contains S1 and KH domains	190
643465621	279	35.8	23	183	3	153	3.0e-31	128	COG0779	Ribosome maturation factor RimP	153
643465622	468	31.35	1	465	17	473	3.0e-71	262	COG1785	Alkaline phosphatase	482
643465623	319	34.47	1	319	1	309	1.0e-63	237	COG2307	Uncharacterized conserved protein, Alpha-E superfamily	313
643465624	503	57.72	2	474	7	479	0.0e+00	652	COG2308	Uncharacterized conserved protein, circularly permuted ATPgrasp superfamily	488
643465626	194	33.33	33	194	38	183	2.0e-19	88.9	COG2335	Uncaracterized surface protein containing fasciclin (FAS1) repeats	187
643465628	248	61	1	240	1	241	7.0e-90	323	COG0217	Transcriptional and/or translational regulatory protein YebC/TACO1	241
643465629	229	35.78	1	197	1	197	7.0e-34	137	COG0625	Glutathione S-transferase	211
643465630	303	38.65	5	282	60	333	2.0e-67	249	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
643465631	342	44.9	17	329	3	289	3.0e-78	285	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
643465635	270	34.96	16	259	18	276	8.0e-38	150	COG3001	Fructosamine-3-kinase	286
643465636	156	43.33	3	152	2	138	2.0e-32	131	COG0394	Protein-tyrosine-phosphatase	139
643465640	438	47.03	12	432	1	420	0.0e+00	500	COG4536	Mg2+ and Co2+ transporter CorB, contains DUF21, CBS pair, and CorC-HlyC domains	423
643465641	615	49.09	29	193	3	167	6.0e-55	209	COG0703	Shikimate kinase	172
643465641	615	51.1	249	612	4	359	3.0e-119	422	COG0337	3-dehydroquinate synthetase	360
643465642	243	33.8	18	232	5	213	2.0e-42	165	COG3047	Outer membrane protein W	213
643465643	729	31.94	50	684	31	625	2.0e-99	357	COG3408	Glycogen debranching enzyme (alpha-1,6-glucosidase)	641
643465644	408	24.81	1	342	1	381	2.0e-26	113	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
643465645	935	24.35	19	246	2	226	5.0e-16	80.8	COG3063	Tfp pilus assembly protein PilF	250
643465647	364	47.09	19	361	3	340	2.0e-91	329	COG1420	Transcriptional regulator of heat shock response	346
643465648	162	42.02	25	143	8	125	1.0e-14	72.7	COG1846	DNA-binding transcriptional regulator, MarR family	126
643465649	925	44.44	32	918	4	842	0.0e+00	835	COG0249	DNA mismatch repair ATPase MutS	843
643465650	658	59.58	39	658	7	627	0.0e+00	807	COG3158	K+ transporter	627
643465651	439	56.46	1	418	1	413	0.0e+00	559	COG1004	UDP-glucose 6-dehydrogenase	414
643465652	538	26.38	188	527	38	336	2.0e-25	111	COG0642	Signal transduction histidine kinase	336
643465653	561	36.45	242	561	1	305	2.0e-60	227	COG0492	Thioredoxin reductase	305
643465654	568	35.81	4	386	1	390	1.0e-44	175	COG0475	Kef-type K+ transport system, membrane component KefB	397
643465655	131	33.64	2	111	10	119	6.0e-14	69.6	COG4270	Uncharacterized membrane protein	131
643465656	242	25.39	49	238	36	227	4.0e-07	48.7	COG0671	Membrane-associated phospholipid phosphatase	232
643465657	312	25	18	304	1	301	2.0e-21	96.9	COG1597	Diacylglycerol kinase family enzyme	301
643465658	278	28.91	8	252	1	250	3.0e-23	102	COG1409	3',5'-cyclic AMP phosphodiesterase CpdA	301
643465661	383	31.23	6	376	4	379	1.0e-60	227	COG3287	Uncharacterized conserved protein, contains FIST_N domain	379
643465662	487	26.48	24	342	25	335	7.0e-30	125	COG0642	Signal transduction histidine kinase	336
643465663	209	38.46	3	203	2	207	1.0e-41	162	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
643465664	506	43.83	19	499	1	470	0.0e+00	500	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
643465668	164	31.82	20	148	9	138	1.0e-21	95.8	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
643465670	186	36.9	19	186	1	166	1.0e-23	102	COG2862	Uncharacterized membrane protein YqhA	169
643465671	616	24.47	48	395	2	371	2.0e-33	137	COG0515	Serine/threonine protein kinase	384
643465673	233	23.32	1	223	5	215	2.0e-16	79.4	COG3913	Uncharacterized protein	227
643465674	1181	33.03	14	1181	19	1187	0.0e+00	761	COG3523	Type VI protein secretion system component VasK	1188
643465675	494	27.42	304	488	5	185	7.0e-23	102	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
643465675	494	32.79	76	322	19	259	8.0e-43	168	COG3455	Type VI protein secretion system component VasF	262
643465676	446	39.24	2	443	1	446	4.0e-102	365	COG3522	Predicted component of the type VI protein secretion system	446
643465677	453	25.71	1	453	1	426	4.0e-52	199	COG3456	Predicted component of the type VI protein secretion system, contains a FHA domain	430
643465679	619	39.46	2	549	3	544	0.0e+00	494	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
643465682	183	50	5	173	3	169	2.0e-44	171	COG3516	Predicted component of the type VI protein secretion system	169
643465683	504	53.59	1	502	1	493	0.0e+00	675	COG3517	Predicted component of the type VI protein secretion system	495
643465684	161	32.14	1	161	1	162	6.0e-31	126	COG3157	Type VI protein secretion system component Hcp (secreted cytotoxin)	162
643465685	182	32.28	54	179	31	153	1.0e-08	53.4	COG3518	Predicted component of the type VI protein secretion system	157
643465686	652	34.15	1	652	1	621	2.0e-123	437	COG3519	Type VI protein secretion system component VasA	621
643465687	349	37.58	6	306	15	320	1.0e-62	233	COG3520	Predicted component of the type VI protein secretion system	335
643465688	904	40.32	12	876	1	782	0.0e+00	758	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
643465694	325	30.32	168	321	35	184	3.0e-14	72.9	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
643465695	96	41.41	1	96	1	98	4.0e-08	49.9	COG4104	Zn-binding Pro-Ala-Ala-Arg (PAAR) domain, incolved in TypeVI secretion	98
643465701	569	35.85	44	530	4	458	2.0e-87	317	COG2272	Carboxylesterase type B	491
643465702	340	29.55	34	340	1	299	7.0e-45	174	COG3735	Uncharacterized conserved protein YbaP, TraB family	299
643465705	234	25.58	3	206	1	196	2.0e-07	49.8	COG0625	Glutathione S-transferase	211
643465706	339	32.59	5	316	2	312	8.0e-53	201	COG1907	Predicted archaeal sugar kinase	312
643465708	381	26.72	12	362	14	366	9.0e-32	131	COG2232	Predicted ATP-dependent carboligase, ATP-grasp superfamily	389
643465709	322	41.69	6	322	1	313	5.0e-76	277	COG3252	Methenyltetrahydromethanopterin cyclohydrolase	314
643465710	321	26.33	22	307	32	317	6.0e-30	125	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
643465711	310	24.67	18	302	8	283	6.0e-16	78.5	COG1767	Triphosphoribosyl-dephospho-CoA synthetase	288
643465712	175	54.32	12	173	2	163	7.0e-48	183	COG1795	Formaldehyde-activating enzyme nesessary for methanogenesis	170
643465713	237	37.72	1	222	1	218	4.0e-31	128	COG1411	Uncharacterized protein related to proFAR isomerase (HisA)	229
643465714	345	31.98	4	342	5	330	9.0e-42	164	COG1548	Uncharacterized protein, hydantoinase/oxoprolinase family	330
643465715	185	21.79	1	170	14	189	5.0e-10	57.6	COG2457	Uncharacterized protein	199
643465716	464	29.52	237	433	70	274	1.0e-10	61.5	COG0294	Dihydropteroate synthase	274
643465717	213	26.09	5	177	3	184	2.0e-19	89.3	COG2054	Uncharacterized archaeal kinase related to aspartokinase	212
643465718	396	29.41	256	370	3	121	9.0e-14	71.8	COG1539	Dihydroneopterin aldolase	121
643465718	396	34.42	4	206	3	217	3.0e-23	103	COG1891	Uncharacterized protein, UPF0264 family	235
643465719	194	56.68	1	182	3	189	2.0e-71	261	COG0512	Anthranilate/para-aminobenzoate synthase component II	191
643465720	457	42.92	8	454	6	458	4.0e-120	425	COG0147	Anthranilate/para-aminobenzoate synthases component I	462
643465722	369	26.33	9	358	61	425	6.0e-25	108	COG1029	Formylmethanofuran dehydrogenase subunit B	429
643465723	542	37.08	4	536	6	570	5.0e-117	415	COG1229	Formylmethanofuran dehydrogenase subunit A	575
643465724	302	45.18	4	301	1	297	5.0e-80	291	COG2037	Formylmethanofuran:tetrahydromethanopterin formyltransferase	297
643465725	268	36	1	220	2	226	2.0e-30	126	COG2218	Formylmethanofuran dehydrogenase subunit C	264
643465728	127	39.56	11	99	7	96	2.0e-16	78.4	COG2154	Pterin-4a-carbinolamine dehydratase	101
643465729	311	40.13	1	306	1	293	1.0e-69	256	COG1131	ABC-type multidrug transport system, ATPase component	293
643465731	435	39.81	13	431	18	438	8.0e-52	198	COG0038	H+/Cl- antiporter ClcA	443
643465732	433	25.94	10	431	6	413	3.0e-51	196	COG1914	Mn2+ and Fe2+ transporters of the NRAMP family	416
643465734	274	47.7	8	246	65	294	7.0e-70	257	COG4302	Ethanolamine ammonia-lyase, small subunit	294
643465735	462	61.5	1	439	1	438	0.0e+00	704	COG4303	Ethanolamine ammonia-lyase, large subunit	453
643465736	477	27.05	14	456	7	450	2.0e-28	120	COG0531	Amino acid transporter	466
643465737	155	25.37	8	141	11	133	2.0e-07	48.4	COG5622	Protein required for attachment to host cells	139
643465739	764	23.39	20	763	13	765	1.0e-100	360	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
643465740	412	18.73	79	408	72	392	3.0e-06	46.7	COG2814	Predicted arabinose efflux permease, MFS family	394
643465741	314	46.06	134	298	7	162	9.0e-42	164	COG1045	Serine acetyltransferase	194
643465742	317	32.39	1	317	2	309	8.0e-31	128	COG0679	Predicted permease	311
643465743	322	38.32	5	322	3	322	2.0e-68	252	COG0598	Mg2+ and Co2+ transporter CorA	322
643465745	132	44.96	2	130	1	128	5.0e-22	96.6	COG3742	Uncharacterized protein, contains PIN domain	131
643465747	578	39.82	25	574	10	510	0.0e+00	490	COG0155	Sulfite reductase, beta subunit (hemoprotein)	510
643465748	608	48.57	18	608	1	587	0.0e+00	572	COG0369	Sulfite reductase, alpha subunit (flavoprotein)	587
643465749	584	43.26	11	579	1	522	6.0e-125	441	COG1620	L-lactate permease	522
643465751	481	44.9	14	472	3	459	0.0e+00	481	COG1139	L-lactate utilization protein LutB, contains a ferredoxin-type domain	459
643465752	220	26.18	1	217	1	218	9.0e-18	83.8	COG1556	L-lactate utilization protein LutC, contains LUD domain	218
643465753	220	24.47	17	204	1	188	2.0e-09	55.8	COG1309	DNA-binding transcriptional regulator, AcrR family	201
643465754	395	40.85	43	392	1	338	7.0e-67	247	COG1566	Multidrug resistance efflux pump	352
643465756	500	35.12	45	491	16	456	7.0e-67	248	COG1538	Outer membrane protein TolC	457
643465758	218	44.61	1	202	1	202	3.0e-40	158	COG0406	Broad specificity phosphatase PhoE	208
643465760	332	40.06	1	327	4	337	2.0e-92	332	COG1064	D-arabinose 1-dehydrogenase, Zn-dependent alcohol dehydrogenase family	339
643465761	509	23.93	93	325	58	289	1.0e-22	101	COG0668	Small-conductance mechanosensitive channel	316
643465761	509	31.37	351	500	4	154	2.0e-13	71.4	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
643465763	135	40.58	1	134	2	139	2.0e-24	104	COG3193	Uncharacterized conserved protein GlcG, DUF336 family	141
643465764	237	26.83	10	213	1	201	4.0e-09	55	COG1309	DNA-binding transcriptional regulator, AcrR family	201
643465765	1073	28.34	2	1043	1	1009	0.0e+00	642	COG0841	Multidrug efflux pump subunit AcrB	1009
643465766	424	30.26	37	424	1	368	3.0e-23	103	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
643465767	342	38.94	15	331	1	316	2.0e-72	266	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
643465768	342	28.41	1	342	1	332	6.0e-29	121	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
643465769	270	36.03	23	268	8	253	3.0e-33	135	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
643465770	255	51.63	6	249	5	246	3.0e-75	275	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
643465772	401	36.96	69	366	23	321	1.0e-74	273	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
643465773	303	26.71	1	290	1	288	8.0e-30	124	COG0583	DNA-binding transcriptional regulator, LysR family	297
643465774	158	47.83	1	158	3	161	3.0e-55	207	COG0386	Glutathione peroxidase, house-cleaning role in reducing lipid peroxides	162
643465775	68	72.06	1	68	1	68	7.0e-23	98.9	COG3360	Flavin-binding protein dodecin	71
643465776	594	27.39	293	583	1	293	2.0e-32	134	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
643465777	1076	21.46	50	1049	36	981	4.0e-102	366	COG3459	Cellobiose phosphorylase	1056
643465779	140	44	1	123	1	123	1.0e-32	132	COG3795	Uncharacterized conserved protein	123
643465780	209	43.7	38	155	1	119	1.0e-26	112	COG1733	DNA-binding transcriptional regulator, HxlR family	120
643465781	731	27.27	14	731	1	728	1.0e-83	304	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
643465782	159	50.67	1	149	2	151	8.0e-49	186	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
643465784	1078	44.05	2	1040	1	1009	0.0e+00	932	COG0841	Multidrug efflux pump subunit AcrB	1009
643465785	390	30.85	1	380	1	371	3.0e-29	123	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
643465786	485	57.68	1	478	11	491	0.0e+00	690	COG0753	Catalase	496
643465790	325	24.34	31	285	14	259	4.0e-07	49.1	COG1240	Mg-chelatase subunit ChlD	261
643465793	335	42.72	26	332	17	325	3.0e-55	209	COG0714	MoxR-like ATPase	329
643465794	1792	32.48	1015	1364	14	330	7.0e-40	160	COG0642	Signal transduction histidine kinase	336
643465797	439	40.05	10	438	1	421	1.0e-97	350	COG1253	Hemolysin or related protein, contains CBS domains	429
643465798	345	30.9	11	342	15	368	5.0e-64	238	COG2021	Homoserine acetyltransferase	368
643465800	246	30.71	11	246	8	246	2.0e-27	116	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
643465803	399	19.93	122	392	112	380	7.0e-18	85.1	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
643465805	331	46.65	4	329	1	324	8.0e-94	337	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
643465806	177	45.24	12	174	1	168	3.0e-44	171	COG3807	SH3-like domain	171
643465810	327	53.21	1	327	1	322	2.0e-107	382	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
643465811	249	34.92	1	246	2	252	1.0e-14	73.9	COG0730	Uncharacterized membrane protein YfcA	258
643465812	237	34.06	25	234	2	228	4.0e-27	115	COG1376	Lipoprotein-anchoring transpeptidase ErfK/SrfK	232
643465813	151	24.55	11	120	6	101	2.0e-09	55.7	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
643465816	153	33.04	33	143	15	126	3.0e-13	68	COG1846	DNA-binding transcriptional regulator, MarR family	126
643465818	395	45.31	6	378	8	366	8.0e-113	400	COG1485	Predicted ATPase	367
643465819	321	44.84	5	313	2	308	2.0e-99	356	COG0039	Malate/lactate dehydrogenase	313
643465820	294	65.99	1	294	1	291	4.0e-115	408	COG0074	Succinyl-CoA synthetase, alpha subunit	293
643465821	1018	54.9	31	1017	1	905	0.0e+00	1316	COG0567	2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes	906
643465822	428	52.33	1	427	1	404	7.0e-111	394	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
643465823	470	51.62	1	460	3	454	0.0e+00	499	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
643465826	295	33.92	10	289	1	281	8.0e-63	234	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
643465827	179	24.56	47	159	13	126	1.0e-09	56.1	COG1846	DNA-binding transcriptional regulator, MarR family	126
643465828	244	36.96	18	243	2	228	4.0e-51	194	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
643465829	453	28.62	160	453	23	329	2.0e-33	137	COG0642	Signal transduction histidine kinase	336
643465830	165	33.33	42	146	16	123	1.0e-14	72.6	COG2346	Truncated hemoglobin YjbI	133
643465831	156	26.77	21	146	2	128	4.0e-11	60.8	COG5649	Uncharacterized protein	132
643465832	292	37.16	147	291	21	167	3.0e-18	85.9	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
643465833	299	35.81	154	298	21	167	1.0e-17	84	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
643465834	349	27.05	58	347	17	296	1.0e-40	160	COG2177	Cell division protein FtsX	297
643465835	220	53.18	1	220	1	219	6.0e-79	287	COG2884	ABC-type ATPase involved in cell division	223
643465836	133	28.46	1	120	6	127	2.0e-09	55	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
643465837	412	49.39	5	412	2	404	0.0e+00	473	COG1364	N-acetylglutamate synthase (N-acetylornithine aminotransferase)	404
643465839	322	25.67	7	288	2	298	1.0e-11	64.4	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
643465841	949	52.34	2	942	1	822	0.0e+00	1023	COG0653	Preprotein translocase subunit SecA (ATPase, RNA helicase)	822
643465843	340	34.38	4	319	9	322	6.0e-24	105	COG0392	Uncharacterized membrane protein YbhN, UPF0104 family	322
643465845	233	40.61	1	224	1	228	4.0e-53	201	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
643465846	227	51.36	4	220	7	214	5.0e-48	184	COG5385	Uncharacterized protein	214
643465847	479	50.78	160	477	16	332	2.0e-94	339	COG3800	Predicted transcriptional regulator	332
643465848	422	73.7	1	422	1	420	0.0e+00	703	COG1158	Transcription termination factor Rho	422
643465849	141	55.56	1	141	5	148	2.0e-37	148	COG1981	Uncharacterized membrane protein	149
643465850	349	46.72	1	348	1	350	2.0e-104	373	COG0407	Uroporphyrinogen-III decarboxylase	352
643465851	277	45.15	8	273	6	273	3.0e-81	295	COG1806	Regulator of PEP synthase PpsR, kinase-PPPase family (combines ADP:protein kinase and phosphorylase activities)	273
643465852	205	40.61	10	205	4	192	2.0e-42	165	COG0424	Predicted house-cleaning NTP pyrophosphatase, Maf/HAM1 superfamily	193
643465853	280	43.21	1	275	2	281	2.0e-72	266	COG0169	Shikimate 5-dehydrogenase	283
643465854	201	32	1	196	2	198	6.0e-38	150	COG0237	Dephospho-CoA kinase	201
643465855	235	39.38	1	223	13	236	3.0e-44	171	COG0847	DNA polymerase III, epsilon subunit or related 3'-5' exonuclease	243
643465856	432	30.53	18	426	4	387	8.0e-72	264	COG0247	Fe-S oxidoreductase	388
643465857	401	25.29	3	399	35	457	8.0e-36	145	COG0277	FAD/FMN-containing dehydrogenase	459
643465861	122	35.65	1	115	1	114	4.0e-18	83.5	COG4737	Uncharacterized protein	123
643465862	107	38.24	5	106	2	103	7.0e-23	98.9	COG2944	DNA-binding transcriptional regulator YiaG, XRE-type HTH domain	104
643465863	358	63.16	51	335	4	282	1.0e-100	359	COG1072	Panthothenate kinase	283
643465864	112	50.55	6	96	1	91	4.0e-21	93.3	COG0140	Phosphoribosyl-ATP pyrophosphohydrolase	92
643465865	256	65.23	1	253	1	256	3.0e-106	377	COG0107	Imidazole glycerol phosphate synthase subunit HisF	256
643465867	246	49.59	1	242	2	241	3.0e-79	288	COG0106	Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase	241
643465868	216	48.15	1	216	2	204	4.0e-71	261	COG0118	Imidazoleglycerol phosphate synthase glutamine amidotransferase subunit HisH	204
643465870	197	64.62	1	195	3	195	3.0e-83	300	COG0131	Imidazoleglycerol phosphate dehydratase HisB	195
643465871	451	38.86	19	439	7	413	8.0e-113	400	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
643465872	776	45.59	387	586	30	233	9.0e-28	119	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
643465873	125	24.17	4	118	8	127	2.0e-11	61.5	COG4319	Ketosteroid isomerase homolog	137
643465874	188	63.48	9	185	2	175	8.0e-69	253	COG5405	ATP-dependent protease HslVU (ClpYQ), peptidase subunit	178
643465875	437	64.29	1	437	1	444	0.0e+00	644	COG1220	ATP-dependent protease HslVU (ClpYQ), ATPase subunit	444
643465876	202	32.31	15	202	12	192	4.0e-17	81.3	COG5516	Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding	196
643465877	289	26.39	3	283	1	282	2.0e-17	82.8	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
643465878	288	41.11	1	284	1	276	8.0e-64	237	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
643465879	238	33.91	6	234	1	221	1.0e-36	147	COG1285	Uncharacterized membrane protein YhiD, involved in acid resistance	221
643465880	456	24.7	9	436	9	493	3.0e-54	205	COG3511	Phospholipase C	527
643465881	207	28.86	38	180	25	173	3.0e-20	92	COG3576	Predicted flavin-nucleotide-binding protein, pyridoxine 5'-phosphate oxidase superfamily	173
643465882	182	30	12	173	8	176	1.0e-10	59.4	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
643465883	344	45.15	1	324	1	314	1.0e-99	356	COG0180	Tryptophanyl-tRNA synthetase	314
643465884	484	22.11	3	475	5	436	7.0e-45	175	COG2610	H+/gluconate symporter or related permease	442
643465885	116	37.36	27	116	12	102	2.0e-07	47.9	COG0640	DNA-binding transcriptional regulator, ArsR family	110
643465887	118	30.28	1	109	6	114	1.0e-13	68.5	COG0599	Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family	124
643465889	358	27.24	17	302	8	292	1.0e-10	61.4	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
643465891	620	40.2	27	619	6	598	0.0e+00	542	COG1164	Oligoendopeptidase F	598
643465892	515	23.08	91	487	69	390	2.0e-29	124	COG4222	Uncharacterized conserved protein	391
643465893	508	38.82	1	489	3	464	2.0e-102	366	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
643465895	629	33.77	115	625	28	550	9.0e-87	315	COG2989	Murein L,D-transpeptidase YcbB/YkuD	561
643465896	285	29.67	13	278	9	257	6.0e-42	164	COG0300	Short-chain dehydrogenase	265
643465897	243	50	1	242	4	249	5.0e-54	204	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
643465898	744	44.77	10	743	3	730	0.0e+00	740	COG1198	Primosomal protein N' (replication factor Y) - superfamily II helicase	730
643465901	691	39.27	9	690	8	667	0.0e+00	600	COG1331	Uncharacterized conserved protein YyaL, SSP411 family, contains thoiredoxin and six-hairpin glycosidase-like domains	667
643465902	448	40.18	15	448	5	454	3.0e-114	405	COG0486	tRNA U34 5-carboxymethylaminomethyl modifying GTPase MnmE/TrmE	454
643465903	620	55.14	1	619	1	621	0.0e+00	860	COG0445	tRNA U34 5-carboxymethylaminomethyl modifying enzyme MnmG/GidA	621
643465904	219	30	16	217	7	212	1.0e-36	146	COG0357	16S rRNA G527 N7-methylase RsmG (former glucose-inhibited division protein B)	215
643465905	282	39.08	17	275	3	253	9.0e-59	220	COG1192	Cellulose biosynthesis protein BcsQ	259
643465906	294	38	42	287	8	240	6.0e-29	121	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
643465907	161	51.92	1	156	1	156	2.0e-48	184	COG2193	Bacterioferritin (cytochrome b1)	157
643465910	397	26.61	17	367	9	351	8.0e-60	224	COG0641	Sulfatase maturation enzyme AslB, radical SAM superfamily	378
643465912	117	63.79	1	116	1	116	8.0e-44	168	COG5507	Uncharacterized  conserved protein YbaA, DUF1428 family	117
643465913	295	39.65	1	284	1	283	7.0e-59	220	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
643465914	126	36.13	5	119	1	119	3.0e-13	67.6	COG3152	Uncharacterized membrane protein YhaH, DUF805 family	125
643465915	311	33.22	1	306	1	305	3.0e-56	212	COG1893	Ketopantoate reductase	307
643465916	357	24.92	1	323	2	320	6.0e-23	102	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
643465917	272	30.94	6	270	1	258	6.0e-33	134	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
643465918	256	43.57	1	241	1	221	4.0e-67	248	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
643465919	270	34.22	29	244	28	252	2.0e-41	162	COG3665	Uncharacterized conserved protein YcgI, DUF1989 family	264
643465920	214	38.35	10	209	42	247	1.0e-53	202	COG3665	Uncharacterized conserved protein YcgI, DUF1989 family	264
643465921	1172	33.47	770	1017	1	216	2.0e-44	175	COG2049	Allophanate hydrolase subunit 1	223
643465921	1172	45	1	551	1	554	0.0e+00	560	COG4770	Acetyl/propionyl-CoA carboxylase, alpha subunit	645
643465922	601	36.54	1	449	2	468	5.0e-84	305	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
643465923	371	45.24	1	342	3	336	3.0e-96	345	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
643465924	238	35.89	19	221	9	217	5.0e-17	81.5	COG3619	Uncharacterized membrane protein YoaK, UPF0700 family	226
643465925	433	16.91	1	414	4	409	3.0e-12	66.7	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
643465927	407	28.08	123	407	97	381	3.0e-30	126	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
643465930	427	50	8	412	4	405	7.0e-124	437	COG1252	NADH dehydrogenase, FAD-containing subunit	405
643465931	674	25.51	34	674	11	594	3.0e-61	230	COG0729	Outer membrane translocation and assembly module TamA	594
643465932	1424	19.82	8	1416	7	1272	1.0e-70	262	COG2911	Autotransporter translocation and assembly factor TamB	1278
643465933	236	23.15	23	233	9	205	5.0e-11	61.4	COG0625	Glutathione S-transferase	211
643465934	140	30.23	10	135	4	132	1.0e-19	88.8	COG0824	Acyl-CoA thioesterase FadM	137
643465935	421	20.88	82	312	9	253	2.0e-14	74.1	COG0584	Glycerophosphoryl diester phosphodiesterase	257
643465937	603	33.06	1	598	4	607	2.0e-121	430	COG2905	Signal-transduction protein containing cAMP-binding, CBS, and nucleotidyltransferase domains	610
643465938	563	56.31	32	554	2	528	0.0e+00	519	COG4147	Na+(or H+)/acetate symporter ActP	529
643465939	101	48.48	1	99	1	99	4.0e-23	99.6	COG3162	Uncharacterized membrane protein, DUF485 family	102
643465943	474	25.85	24	454	9	449	5.0e-31	129	COG0531	Amino acid transporter	466
643465947	299	23.9	1	298	12	369	4.0e-41	162	COG0067	Glutamate synthase domain 1	371
643465949	444	35.63	8	424	54	485	3.0e-107	382	COG0069	Glutamate synthase domain 2	485
643465950	435	39.18	11	435	10	443	7.0e-118	417	COG0174	Glutamine synthetase	443
643465951	416	31.73	28	404	1	387	8.0e-53	201	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
643465952	95	43.33	1	89	2	87	1.0e-21	95	COG4311	Sarcosine oxidase delta subunit	97
643465953	984	34.09	588	984	1	379	1.0e-84	308	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
643465954	209	31.35	16	200	10	189	1.0e-17	83.5	COG4583	Sarcosine oxidase gamma subunit	189
643465955	131	23.81	4	130	2	142	1.0e-05	42.2	COG0262	Dihydrofolate reductase	167
643465956	233	27.03	6	219	4	220	1.0e-20	93.4	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
643465958	335	46.51	1	335	3	345	1.0e-72	267	COG1294	Cytochrome bd-type quinol oxidase, subunit 2	346
643465959	474	46.83	3	453	1	455	0.0e+00	478	COG1271	Cytochrome bd-type quinol oxidase, subunit 1	457
643465961	344	28.38	1	194	13	233	2.0e-21	97.2	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
643465961	344	29.52	240	344	9	108	1.0e-14	74.2	COG0607	Rhodanese-related sulfurtransferase	110
643465962	220	39.51	1	199	1	193	2.0e-57	215	COG0450	Alkyl hydroperoxide reductase subunit AhpC (peroxiredoxin)	194
643465964	349	33.63	7	338	16	318	2.0e-47	182	COG0226	ABC-type phosphate transport system, periplasmic component	318
643465965	272	58.43	18	271	6	252	3.0e-108	384	COG1117	ABC-type phosphate transport system, ATPase component	253
643465966	304	41.4	24	301	3	286	3.0e-54	205	COG0581	ABC-type phosphate transport system, permease component	292
643465967	322	41.59	9	318	2	309	4.0e-61	228	COG0573	ABC-type phosphate transport system, permease component	310
643465968	343	31.34	3	331	15	317	1.0e-49	190	COG0226	ABC-type phosphate transport system, periplasmic component	318
643465969	736	53.01	25	717	5	696	0.0e+00	903	COG0855	Polyphosphate kinase	696
643465970	733	72.34	1	733	12	730	0.0e+00	1110	COG0376	Catalase (peroxidase I)	730
643465971	160	34.55	1	160	2	148	1.0e-22	99.3	COG0716	Flavodoxin	151
643465973	254	36.76	5	253	12	283	4.0e-37	148	COG5486	Predicted metal-binding membrane protein	283
643465974	200	38	3	199	6	205	4.0e-43	167	COG5588	Uncharacterized protein	207
643465975	278	26.5	138	252	2	118	4.0e-10	59.1	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
643465976	286	24.43	1	217	2	207	2.0e-11	63.4	COG0725	ABC-type molybdate transport system, periplasmic component	258
643465977	278	20.87	1	201	4	197	1.0e-07	51.1	COG0725	ABC-type molybdate transport system, periplasmic component	258
643465979	574	25.44	41	546	42	533	1.0e-53	204	COG2831	Hemolysin activation/secretion protein	554
643465981	127	31.2	3	123	10	133	6.0e-18	83	COG0848	Biopolymer transport protein ExbD	137
643465982	252	25	9	248	2	237	1.0e-11	63.6	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
643465983	377	31.52	17	356	4	334	9.0e-39	154	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
643465984	389	24.23	4	380	3	387	1.0e-36	147	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
643465985	367	26.56	45	343	5	305	2.0e-22	100	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
643465986	346	31.66	87	343	1	257	5.0e-31	128	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
643465987	262	53.06	16	259	4	244	6.0e-83	300	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
643465988	201	32.8	4	191	7	189	3.0e-42	164	COG5553	Predicted metal-dependent enzyme of the double-stranded beta helix superfamily	191
643465990	300	34.01	8	296	3	289	5.0e-32	131	COG0583	DNA-binding transcriptional regulator, LysR family	297
643465991	285	23.58	1	229	2	228	2.0e-16	79.6	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
643465992	418	35.51	209	418	1	208	4.0e-39	155	COG2140	Oxalate decarboxylase/archaeal phosphoglucose isomerase, cupin superfamily	209
643465993	259	21.43	28	257	19	282	2.0e-07	50.1	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
643465996	222	51.78	13	209	5	201	4.0e-60	224	COG4566	Two-component response regulator, FixJ family, consists of REC and HTH domains	202
643466000	174	21.43	27	173	10	163	4.0e-06	44.7	COG4961	Flp pilus assembly protein TadG	185
643466002	227	26.35	87	227	39	186	5.0e-10	58.1	COG2020	Protein-S-isoprenylcysteine O-methyltransferase Ste14	187
643466003	179	33.05	3	118	1	118	2.0e-06	45.6	COG4960	Flp pilus assembly protein, protease CpaA	168
643466004	338	32.68	5	256	4	245	2.0e-24	106	COG3745	Flp pilus assembly protein CpaB	276
643466005	389	26.24	112	389	77	358	2.0e-24	107	COG4963	Flp pilus assembly protein, ATPase CpaE	366
643466006	462	51.44	70	417	12	354	4.0e-112	398	COG4962	Pilus assembly protein, ATPase of CpaF family	355
643466007	319	27.3	12	314	9	306	8.0e-35	141	COG4965	Flp pilus assembly protein TadB	309
643466008	320	33.76	80	315	86	318	4.0e-19	89.1	COG2064	Pilus assembly protein TadC	320
643466009	530	39.06	35	522	1	447	4.0e-89	322	COG4964	Flp pilus assembly protein, secretin CpaC	455
643466015	333	27.73	8	263	14	264	3.0e-25	109	COG1566	Multidrug resistance efflux pump	352
643466017	367	25.42	43	334	16	305	8.0e-25	108	COG1566	Multidrug resistance efflux pump	352
643466018	323	26.18	7	321	1	295	1.0e-24	107	COG0583	DNA-binding transcriptional regulator, LysR family	297
643466019	317	28.53	16	309	5	327	2.0e-48	186	COG0280	Phosphotransacetylase	327
643466020	398	47.12	7	396	3	396	2.0e-124	439	COG0282	Acetate kinase	396
643466023	258	51.2	8	257	4	253	6.0e-81	294	COG0623	Enoyl-[acyl-carrier-protein] reductase (NADH)	259
643466024	190	48.88	1	178	1	173	3.0e-56	211	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase or related enzyme	173
643466025	356	60.29	7	354	1	337	0.0e+00	530	COG1088	dTDP-D-glucose 4,6-dehydratase	340
643466026	291	50.17	1	288	2	281	5.0e-85	307	COG1091	dTDP-4-dehydrorhamnose reductase	281
643466027	289	56.18	2	284	1	280	8.0e-107	380	COG1209	dTDP-glucose pyrophosphorylase	286
643466028	393	29.22	52	291	13	239	6.0e-31	128	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
643466031	308	33.77	4	303	2	308	6.0e-49	188	COG0451	Nucleoside-diphosphate-sugar epimerase	314
643466032	498	25.17	197	479	91	377	2.0e-22	101	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
643466033	662	28.68	391	643	3	253	5.0e-22	99.8	COG1216	Glycosyltransferase, GT2 family	305
643466035	411	28.38	41	407	9	370	2.0e-48	187	COG3524	Capsule polysaccharide export protein KpsE/RkpR	372
643466036	432	28.96	68	431	20	371	8.0e-48	184	COG3524	Capsule polysaccharide export protein KpsE/RkpR	372
643466037	2492	26.25	2088	2312	5	243	5.0e-10	62.2	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
643466037	2492	35.91	1754	2069	11	326	1.0e-51	200	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
643466037	2492	39.5	21	1061	8	1026	0.0e+00	701	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
643466038	430	22.57	146	430	93	377	6.0e-20	92.4	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
643466042	464	43.99	77	441	22	386	3.0e-101	362	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
643466044	216	32.77	1	214	3	240	9.0e-57	213	COG1134	ABC-type polysaccharide/polyol phosphate transport system, ATPase component	249
643466045	394	31.14	30	378	17	357	2.0e-51	196	COG3524	Capsule polysaccharide export protein KpsE/RkpR	372
643466049	1220	20.32	816	1182	1	348	1.0e-14	76.6	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
643466050	268	18.18	24	265	19	257	2.0e-13	70.2	COG1682	ABC-type polysaccharide/polyol phosphate export permease	263
643466053	349	48.82	18	349	3	339	6.0e-92	331	COG0309	Hydrogenase maturation factor	339
643466054	381	51.08	1	369	1	364	3.0e-130	458	COG0409	Hydrogenase maturation factor	364
643466055	82	41.43	1	68	1	70	3.0e-11	60.3	COG0298	Hydrogenase maturation factor	82
643466056	760	43.7	13	744	1	745	0.0e+00	711	COG0068	Hydrogenase maturation factor HypF (carbamoyltransferase)	750
643466057	293	45.89	80	282	1	200	1.0e-60	226	COG0378	Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase	202
643466058	113	44.25	1	113	1	113	2.0e-26	111	COG0375	Zn finger protein HypA/HybF (possibly regulating hydrogenase expression)	115
643466060	163	23.53	15	158	3	155	4.0e-08	51.1	COG0680	Ni,Fe-hydrogenase maturation factor	160
643466061	488	40.44	17	471	4	432	7.0e-108	384	COG3259	Coenzyme F420-reducing hydrogenase, alpha subunit	441
643466064	603	31.08	7	154	11	158	3.0e-25	110	COG1905	NADH:ubiquinone oxidoreductase 24 kD subunit (chain E)	160
643466064	603	42.78	198	573	35	421	3.0e-115	409	COG1894	NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F)	424
643466066	236	37.37	45	236	1	196	6.0e-38	150	COG0288	Carbonic anhydrase	207
643466071	574	33.82	15	562	9	550	2.0e-86	313	COG0659	Sulfate permease or related transporter, MFS superfamily	554
643466073	433	24.09	32	314	24	314	4.0e-22	99.6	COG2358	TRAP-type uncharacterized transport system, periplasmic component	321
643466076	72	36.36	14	68	11	65	1.0e-06	44.9	COG3311	Predicted DNA-binding transcriptional regulator AlpA	70
643466090	504	35.55	10	263	3	258	5.0e-39	156	COG0467	RecA-superfamily ATPase, KaiC/GvpD/RAD55 family	260
643466092	260	40.08	3	249	1	261	1.0e-62	233	COG3546	Mn-containing catalase (includes spore coat protein CotJC)	277
643466093	325	27.21	51	325	1	280	9.0e-21	94.4	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
643466094	197	28.91	1	193	1	206	2.0e-26	112	COG2135	Putative SOS response-associated peptidase YedK	226
643466107	327	30.17	23	316	23	303	1.0e-32	133	COG4313	Uncharacterized conserved protein	304
643466109	485	20.19	37	343	4	314	3.0e-18	86.9	COG2358	TRAP-type uncharacterized transport system, periplasmic component	321
643466110	340	38.08	3	312	1	315	3.0e-59	222	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
643466111	937	42.84	46	928	1	867	0.0e+00	848	COG2844	UTP:GlnB (protein PII) uridylyltransferase	867
643466112	187	42.21	31	184	45	193	8.0e-38	150	COG0576	Molecular chaperone GrpE (heat shock protein)	193
643466113	393	23.29	70	352	65	354	4.0e-22	99.3	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
643466114	127	48.04	17	118	9	110	4.0e-33	133	COG1733	DNA-binding transcriptional regulator, HxlR family	120
643466115	207	34.5	16	207	5	204	4.0e-25	108	COG3218	ABC-type uncharacterized transport system, auxiliary component	205
643466116	357	26.35	1	270	1	274	4.0e-30	125	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
643466117	257	55.69	1	246	11	256	3.0e-95	341	COG1127	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, ATPase component MlaF	263
643466118	379	41.79	110	377	3	265	3.0e-59	222	COG0767	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, permease component MlaE	267
643466119	334	33.83	15	326	13	341	1.0e-35	144	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
643466121	499	33.19	21	488	4	459	1.0e-83	304	COG1109	Phosphomannomutase	464
643466123	326	53.05	11	320	3	305	2.0e-95	342	COG0492	Thioredoxin reductase	305
643466125	125	27.34	3	124	8	135	1.0e-08	51.8	COG2246	Putative flippase GtrA (transmembrane translocase of bactoprenol-linked glucose)	139
643466127	577	38.05	5	540	3	538	0.0e+00	470	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
643466128	159	37.01	1	152	5	158	1.0e-21	95.7	COG3476	Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)	161
643466129	219	26.54	3	210	1	211	7.0e-24	104	COG0625	Glutathione S-transferase	211
643466130	159	28.21	11	127	10	118	5.0e-12	63.9	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
643466132	151	37.06	5	145	4	146	7.0e-26	109	COG1762	Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type)	152
643466133	230	41.48	7	230	2	229	8.0e-54	203	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
643466134	901	52.77	9	891	4	879	0.0e+00	1018	COG2205	K+-sensing histidine kinase KdpD	890
643466135	200	60	1	197	1	189	1.0e-67	249	COG2156	K+-transporting ATPase, c chain	190
643466136	702	68.71	3	702	1	681	0.0e+00	991	COG2216	High-affinity K+ transport system, ATPase chain B	681
643466137	569	65.71	5	560	4	559	0.0e+00	743	COG2060	K+-transporting ATPase, A chain	560
643466139	296	23.26	2	294	31	326	4.0e-21	95.6	COG3239	Fatty acid desaturase	343
643466140	271	22.09	25	267	54	299	3.0e-24	105	COG3221	ABC-type phosphate/phosphonate transport system, periplasmic component	299
643466142	497	22.84	50	472	35	457	1.0e-25	111	COG0531	Amino acid transporter	466
643466143	210	21.98	12	192	9	190	4.0e-06	45	COG1309	DNA-binding transcriptional regulator, AcrR family	201
643466144	258	45.34	5	247	1	245	2.0e-66	245	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
643466145	411	33.67	21	311	4	282	9.0e-42	164	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
643466146	276	36.99	25	270	9	250	1.0e-36	146	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
643466147	177	20.14	37	174	3	132	2.0e-07	48.8	COG1765	Uncharacterized OsmC-related protein	137
643466148	375	19.89	18	370	13	383	1.0e-14	74.4	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
643466150	506	24.51	60	461	39	440	4.0e-25	109	COG0531	Amino acid transporter	466
643466152	316	32.1	40	198	28	189	2.0e-15	76.4	COG3932	Uncharacterized conserved protein	209
643466154	909	24.24	180	825	21	685	3.0e-47	184	COG2217	Cation transport ATPase	713
643466155	872	30.4	203	854	28	713	3.0e-110	393	COG2217	Cation transport ATPase	713
643466156	198	24.31	1	196	40	254	1.0e-16	80.2	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
643466157	604	32.42	15	557	12	537	1.0e-81	297	COG0659	Sulfate permease or related transporter, MFS superfamily	554
643466158	343	47.2	3	338	9	346	4.0e-100	358	COG1613	ABC-type sulfate transport system, periplasmic component	348
643466159	1057	28.8	3	1037	1	1006	0.0e+00	630	COG0841	Multidrug efflux pump subunit AcrB	1009
643466160	421	27.59	21	394	6	368	6.0e-20	92.1	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
643466161	335	38.17	8	317	12	313	3.0e-73	269	COG0042	tRNA-dihydrouridine synthase	323
643466162	299	53.29	12	299	6	286	3.0e-102	365	COG2607	Predicted ATPase, AAA+ superfamily	287
643466163	256	40.98	15	255	8	249	6.0e-68	250	COG3338	Carbonic anhydrase	250
643466164	114	40.82	13	110	1	97	7.0e-23	99.1	COG1862	Preprotein translocase subunit YajC	97
643466165	532	48.15	1	532	1	506	6.0e-129	454	COG0342	Preprotein translocase subunit SecD	506
643466166	318	41.45	4	307	1	300	2.0e-78	285	COG0341	Preprotein translocase subunit SecF	305
643466167	132	51.28	14	130	12	127	1.0e-25	108	COG3737	Uncharacterized conserved protein, contains Mth938-like domain	127
643466168	287	32.03	9	287	7	287	2.0e-44	172	COG1562	Phytoene/squalene synthetase	288
643466171	171	37.75	8	155	14	160	4.0e-25	107	COG0597	Lipoprotein signal peptidase	167
643466173	457	34.23	10	448	1	438	3.0e-76	279	COG0612	Predicted Zn-dependent peptidase	438
643466174	435	29.14	9	430	1	429	3.0e-62	232	COG0612	Predicted Zn-dependent peptidase	438
643466176	195	42.51	18	183	4	169	3.0e-40	158	COG1247	L-amino acid N-acyltransferase YncA	169
643466177	614	25.9	5	607	112	773	4.0e-67	249	COG4993	Glucose dehydrogenase	773
643466179	605	41.5	1	605	1	638	0.0e+00	574	COG0323	DNA mismatch repair ATPase MutL	638
643466181	449	57.68	22	440	3	424	0.0e+00	533	COG0151	Phosphoribosylamine-glycine ligase	428
643466182	185	46.45	3	185	12	181	6.0e-39	153	COG2335	Uncaracterized surface protein containing fasciclin (FAS1) repeats	187
643466183	191	43.62	1	184	2	185	3.0e-46	178	COG0742	16S rRNA G966 N2-methylase RsmD	187
643466184	676	40.41	24	265	2	246	4.0e-61	229	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
643466185	153	54.97	3	153	2	152	2.0e-26	111	COG3918	Uncharacterized membrane protein	153
643466186	458	36.4	1	451	1	454	2.0e-110	393	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
643466188	626	27.96	24	278	2	274	5.0e-35	142	COG0515	Serine/threonine protein kinase	384
643466189	262	38.65	1	240	1	251	1.0e-52	200	COG0631	Serine/threonine protein phosphatase PrpC	262
643466190	224	27.57	2	204	7	213	2.0e-18	86.3	COG3913	Uncharacterized protein	227
643466191	1148	33.31	5	1145	9	1184	0.0e+00	695	COG3523	Type VI protein secretion system component VasK	1188
643466192	493	25.15	322	491	23	189	3.0e-17	83.7	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
643466192	493	28.52	55	324	7	261	1.0e-37	151	COG3455	Type VI protein secretion system component VasF	262
643466196	477	40.33	33	451	4	398	1.0e-101	364	COG4992	Acetylornithine/succinyldiaminopimelate/putrescine aminotransferase	404
643466197	199	41.21	12	174	5	169	3.0e-44	171	COG0806	Ribosomal 30S subunit maturation factor RimM, required for 16S rRNA processing	174
643466198	231	55.22	3	231	2	230	3.0e-87	314	COG0336	tRNA G37 N-methylase TrmD	240
643466199	615	22.4	162	579	1	430	4.0e-40	160	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
643466201	260	35.16	34	249	6	224	7.0e-47	180	COG0220	tRNA G46 methylase TrmB	227
643466203	576	31.7	13	563	14	518	4.0e-81	296	COG0815	Apolipoprotein N-acyltransferase	518
643466205	176	40.91	5	156	3	153	2.0e-36	145	COG0319	ssRNA-specific RNase YbeY, 16S rRNA maturation enzyme	153
643466206	355	45.21	25	355	10	341	7.0e-92	330	COG1702	Phosphate starvation-inducible protein PhoH, predicted ATPase	348
643466207	490	47.32	28	471	3	436	0.0e+00	510	COG0621	tRNA A37 methylthiotransferase MiaB	437
643466208	163	30	28	162	28	177	2.0e-13	68.9	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
643466209	234	34.51	1	224	1	219	2.0e-32	132	COG1214	tRNA A37 threonylcarbamoyladenosine modification protein TsaB	220
643466210	187	46.43	106	187	1	84	9.0e-22	96.5	COG0694	Fe-S cluster biogenesis protein NfuA, 4Fe-4S-binding domain	93
643466212	253	38.46	9	248	4	246	2.0e-49	189	COG1385	16S rRNA U1498 N3-methylase RsmE	246
643466214	329	38.89	34	320	7	286	2.0e-39	156	COG0382	4-hydroxybenzoate polyprenyltransferase	289
643466215	712	36.21	24	676	17	706	4.0e-123	436	COG2217	Cation transport ATPase	713
643466220	471	59.27	4	466	2	439	0.0e+00	644	COG1206	Folate-dependent tRNA-U54 methylase TrmFO/GidA	439
643466221	466	27.81	8	466	1	449	1.0e-47	184	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
643466223	462	39.6	1	448	1	441	2.0e-95	342	COG0544	FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)	441
643466224	215	66.83	13	211	2	200	9.0e-81	292	COG0740	ATP-dependent protease ClpP, protease subunit	200
643466225	421	73.96	16	420	1	407	0.0e+00	714	COG1219	ATP-dependent protease Clp, ATPase subunit	408
643466226	805	67.14	7	783	1	782	0.0e+00	1186	COG0466	ATP-dependent Lon protease, bacterial type	782
643466229	449	39.73	3	445	5	451	1.0e-93	337	COG2233	Xanthine/uracil permease	451
643466231	121	52.89	1	121	1	121	1.0e-30	125	COG0838	NADH:ubiquinone oxidoreductase subunit 3 (chain A)	123
643466232	187	67.86	20	187	2	168	1.0e-74	272	COG0377	NADH:ubiquinone oxidoreductase 20 kD subunit (chhain B) or related Fe-S oxidoreductase	194
643466233	204	53.37	1	177	2	176	2.0e-50	191	COG0852	NADH:ubiquinone oxidoreductase 27 kD subunit (chain C)	176
643466234	394	57.72	1	394	8	398	0.0e+00	612	COG0649	NADH:ubiquinone oxidoreductase 49 kD subunit (chain D)	398
643466235	264	50.31	13	172	2	159	5.0e-55	207	COG1905	NADH:ubiquinone oxidoreductase 24 kD subunit (chain E)	160
643466236	436	57.92	1	420	5	424	0.0e+00	648	COG1894	NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F)	424
643466237	687	49.64	1	676	1	679	0.0e+00	737	COG1034	NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)	693
643466238	342	51.67	8	336	9	332	4.0e-97	348	COG1005	NADH:ubiquinone oxidoreductase subunit 1 (chain H)	332
643466239	162	45.18	1	162	1	161	1.0e-46	178	COG1143	Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)	172
643466240	201	45.88	1	170	2	166	2.0e-24	105	COG0839	NADH:ubiquinone oxidoreductase subunit 6 (chain J)	166
643466241	102	62	3	102	2	100	2.0e-20	90.9	COG0713	NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K)	100
643466242	681	42.31	2	674	1	606	0.0e+00	497	COG1009	NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit	606
643466243	503	55.2	2	498	1	496	0.0e+00	545	COG1008	NADH:ubiquinone oxidoreductase subunit 4 (chain M)	497
643466244	477	50.31	4	477	1	475	3.0e-98	352	COG1007	NADH:ubiquinone oxidoreductase subunit 2 (chain N)	475
643466245	259	39.75	21	252	3	236	7.0e-46	177	COG0340	Biotin-(acetyl-CoA carboxylase) ligase	238
643466246	556	36.09	5	554	6	555	0.0e+00	473	COG0595	mRNA degradation ribonuclease J1/J2	555
643466251	177	47.17	13	161	7	165	2.0e-45	175	COG3479	Phenolic acid decarboxylase	175
643466255	528	29.93	1	524	1	531	6.0e-96	344	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
643466256	330	26.06	51	326	1	281	1.0e-20	94	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
643466257	548	32.5	1	423	4	426	3.0e-56	213	COG1283	Na+/phosphate symporter	533
643466258	382	29.61	171	375	76	280	1.0e-13	71.1	COG0842	ABC-type multidrug transport system, permease component	286
643466259	943	30.08	17	497	18	523	2.0e-72	268	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
643466260	365	25.71	30	290	5	277	4.0e-23	102	COG1566	Multidrug resistance efflux pump	352
643466262	710	30.48	13	710	47	765	2.0e-118	419	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
643466264	634	64.23	1	600	4	579	0.0e+00	708	COG0443	Molecular chaperone DnaK (HSP70)	579
643466265	382	55.73	8	378	1	371	0.0e+00	464	COG0484	DnaJ-class molecular chaperone with C-terminal Zn finger domain	371
643466266	284	40.76	26	209	11	191	2.0e-40	159	COG3963	Phospholipid N-methyltransferase	194
643466267	244	47.14	13	237	12	237	6.0e-54	204	COG0284	Orotidine-5'-phosphate decarboxylase	240
643466268	272	49.81	4	268	3	266	2.0e-83	302	COG0289	Dihydrodipicolinate reductase	266
643466270	400	45.68	6	399	1	392	2.0e-112	399	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
643466271	133	67.52	14	130	8	124	1.0e-41	162	COG3651	Uncharacterized conserved protein, DUF2237 family	125
643466273	193	32.92	1	161	1	158	9.0e-20	89.9	COG1238	Uncharacterized membrane protein YqaA, SNARE-associated domain	161
643466274	171	26.83	8	166	13	170	8.0e-13	67	COG1495	Disulfide bond formation protein DsbB	170
643466275	399	48.92	22	392	1	349	3.0e-122	432	COG0820	Adenine C2-methylase RlmN of 23S rRNA A2503 and tRNA A37	349
643466276	250	40.83	11	250	14	243	5.0e-40	158	COG2968	Uncharacterized conserved protein YggE, contains kinase-interacting SIMPL domain	243
643466278	235	57.92	1	221	1	220	2.0e-82	298	COG1788	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit	220
643466279	220	65.58	3	216	6	218	2.0e-80	291	COG2057	Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit	225
643466280	268	35.65	38	267	7	223	7.0e-42	164	COG1040	Predicted amidophosphoribosyltransferases	225
643466281	280	33.69	1	271	3	280	2.0e-42	166	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
643466284	257	52.99	7	257	4	254	2.0e-83	302	COG0623	Enoyl-[acyl-carrier-protein] reductase (NADH)	259
643466286	470	28.57	4	134	13	152	5.0e-08	52.8	COG2030	Acyl dehydratase	159
643466286	470	28.85	180	452	22	323	2.0e-44	173	COG0280	Phosphotransacetylase	327
643466287	404	46.8	5	401	3	396	3.0e-125	441	COG0282	Acetate kinase	396
643466288	174	30	37	174	27	165	4.0e-15	74.3	COG3652	Predicted outer membrane protein	170
643466289	558	27.95	1	549	5	548	1.0e-82	300	COG0659	Sulfate permease or related transporter, MFS superfamily	554
643466290	327	37.84	1	324	16	345	9.0e-61	227	COG0252	L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D	351
643466291	122	59.09	3	90	2	87	4.0e-24	103	COG0228	Ribosomal protein S16	87
643466292	540	52.85	1	456	1	451	0.0e+00	575	COG0541	Signal recognition particle GTPase	451
643466294	531	37.05	7	408	9	407	2.0e-50	193	COG0025	NhaP-type Na+/H+ or K+/H+ antiporter	429
643466295	424	22.19	30	366	36	399	3.0e-12	66.8	COG2271	Sugar phosphate permease	448
643466296	552	34.11	35	427	30	457	1.0e-75	277	COG0493	NADPH-dependent glutamate synthase beta chain or related oxidoreductase	457
643466297	1217	28.8	831	1198	1	294	5.0e-52	200	COG1013	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, beta subunit	294
643466297	1217	28.99	436	639	1	198	8.0e-29	123	COG1014	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, gamma subunit	203
643466297	1217	37.79	17	404	1	362	1.0e-87	318	COG0674	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, alpha subunit	365
643466298	337	29.63	2	309	1	310	3.0e-41	162	COG0167	Dihydroorotate dehydrogenase	310
643466300	122	66.94	1	121	1	121	1.0e-41	161	COG0099	Ribosomal protein S13	121
643466301	129	65.89	1	129	1	129	2.0e-49	187	COG0100	Ribosomal protein S11	129
643466302	338	51.27	11	324	3	313	5.0e-97	348	COG0202	DNA-directed RNA polymerase, alpha subunit/40 kD subunit	317
643466303	142	61.21	1	116	1	116	7.0e-46	176	COG0203	Ribosomal protein L17	116
643466304	476	43.27	29	376	14	347	3.0e-69	256	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
643466305	437	56.37	17	435	13	436	0.0e+00	583	COG2256	Replication-associated recombination protein RarA (DNA-dependent ATPase)	436
643466306	198	55.61	1	192	3	191	2.0e-56	212	COG5394	Polyhydroxyalkanoate (PHA) synthesis regulator protein, binds DNA and PHA	193
643466307	390	48.39	1	390	1	391	7.0e-89	321	COG0183	Acetyl-CoA acetyltransferase	392
643466308	241	40.73	3	238	6	250	2.0e-47	182	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
643466310	609	64.63	130	585	3	432	0.0e+00	731	COG0422	Thiamine biosynthesis protein ThiC	432
643466311	505	51.81	12	505	12	501	0.0e+00	587	COG0427	Acyl-CoA hydrolase	501
643466312	145	43.92	3	145	4	147	4.0e-29	120	COG0590	tRNA(Arg) A34 adenosine deaminase TadA	152
643466313	335	39.13	2	335	1	326	6.0e-57	214	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
643466314	237	46.49	10	237	2	228	2.0e-51	195	COG1346	Putative effector of murein hydrolase	230
643466315	130	40	1	130	7	127	3.0e-16	77.5	COG1380	Putative effector of murein hydrolase LrgA, UPF0299 family	128
643466318	274	27.54	37	270	91	325	4.0e-37	148	COG1723	Uncharacterized protein, Rmd1/YagE family	331
643466319	248	23.4	11	242	4	228	1.0e-16	80.3	COG1011	FMN phosphatase YigB, HAD superfamily	229
643466320	585	51.87	5	565	2	549	0.0e+00	658	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
643466321	187	54.94	26	187	4	163	4.0e-45	174	COG0440	Acetolactate synthase, small subunit	163
643466322	339	67.36	1	337	3	338	0.0e+00	555	COG0059	Ketol-acid reductoisomerase	338
643466327	530	56.49	8	525	5	528	0.0e+00	787	COG4108	Peptide chain release factor RF-3	528
643466328	144	60.58	8	144	4	140	6.0e-43	166	COG5579	Uncharacterized protein, DUF1810 family	143
643466329	270	56.93	1	267	2	263	1.0e-86	312	COG0351	Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase	263
643466332	358	42.18	5	358	1	322	1.0e-90	326	COG0523	GTPase, G3E family	323
643466333	294	29.74	69	294	40	268	5.0e-28	118	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
643466334	505	38.39	37	247	1	210	2.0e-39	157	COG1648	Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain)	210
643466334	505	51.27	253	488	4	235	2.0e-68	253	COG0007	Uroporphyrinogen-III methylase (siroheme synthase)	244
643466335	441	17.88	1	311	1	313	6.0e-12	65.7	COG2358	TRAP-type uncharacterized transport system, periplasmic component	321
643466337	450	52.26	8	447	1	439	2.0e-92	333	COG2610	H+/gluconate symporter or related permease	442
643466338	196	46.58	11	171	1	161	4.0e-53	200	COG3265	Gluconate kinase	161
643466339	605	64.18	1	602	3	603	0.0e+00	972	COG1217	Predicted membrane GTPase involved in stress response	603
643466340	330	31.69	24	304	1	247	1.0e-52	200	COG0152	Phosphoribosylaminoimidazole-succinocarboxamide synthase	247
643466341	150	34.4	1	121	4	128	5.0e-18	83.7	COG1695	DNA-binding transcriptional regulator, PadR family	138
643466342	249	34.75	6	241	4	232	2.0e-37	149	COG1376	Lipoprotein-anchoring transpeptidase ErfK/SrfK	232
643466343	292	46.08	1	292	1	273	4.0e-88	318	COG0266	Formamidopyrimidine-DNA glycosylase	273
643466345	387	22.16	1	342	13	353	1.0e-19	90.8	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
643466347	323	43.26	3	316	4	316	2.0e-72	265	COG4301	Uncharacterized conserved protein, contains predicted SAM-dependent methyltransferase domain	321
643466348	429	26.84	197	426	59	310	3.0e-28	120	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
643466350	211	26.23	11	184	10	185	4.0e-07	48.5	COG2932	Phage repressor protein C, contains Cro/C1-type HTH and peptisase s24 domains	214
643466365	202	24.86	26	188	1	172	6.0e-07	47.7	COG5448	Uncharacterized protein	184
643466373	260	28.69	2	228	1	248	1.0e-22	100	COG3926	Lysozyme family protein	252
643466378	588	27.78	524	587	23	94	7.0e-07	49.3	COG0633	Ferredoxin	102
643466378	588	31.25	236	503	1	258	3.0e-44	173	COG1018	Ferredoxin-NADP reductase	266
643466378	588	40.76	3	213	1	208	7.0e-47	182	COG2258	Uncharacterized conserved protein YiiM, contains MOSC domain	210
643466379	433	57.21	17	430	10	423	0.0e+00	520	COG0141	Histidinol dehydrogenase	425
643466380	162	63.52	4	162	3	160	4.0e-59	220	COG5328	Uncharacterized protein, UPF0262 family	160
643466381	151	33.57	9	143	2	139	4.0e-27	113	COG0394	Protein-tyrosine-phosphatase	139
643466382	603	41.11	73	574	11	491	5.0e-99	355	COG0608	Single-stranded DNA-specific exonuclease, DHH superfamily, may be involved in archaeal DNA replication intiation	491
643466408	428	27.46	187	408	66	298	9.0e-17	81.8	COG4974	Site-specific recombinase XerD	300
643466411	197	28.91	1	193	1	206	5.0e-27	114	COG2135	Putative SOS response-associated peptidase YedK	226
643466413	336	37.35	19	334	90	416	5.0e-65	241	COG1793	ATP-dependent DNA ligase	444
643466422	184	38.38	1	179	1	198	5.0e-27	114	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
643466429	427	28.09	151	401	48	283	4.0e-08	53.3	COG4974	Site-specific recombinase XerD	300
643466431	334	31.4	8	324	40	314	5.0e-46	178	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
643466432	326	27.64	8	324	1	302	4.0e-39	155	COG4313	Uncharacterized conserved protein	304
643466433	549	31.84	57	490	1	459	7.0e-71	261	COG3119	Arylsulfatase A or related enzyme	475
643466434	249	34.78	3	216	55	284	2.0e-38	152	COG0122	3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase	285
643466437	165	34.75	27	164	2	141	2.0e-21	95.3	COG3193	Uncharacterized conserved protein GlcG, DUF336 family	141
643466438	184	39.13	21	180	2	157	1.0e-32	133	COG1225	Peroxiredoxin	157
643466439	159	26.26	53	147	12	110	8.0e-07	46.8	COG0607	Rhodanese-related sulfurtransferase	110
643466440	296	42.74	74	296	4	236	2.0e-43	169	COG0412	Dienelactone hydrolase	236
643466444	265	30.69	37	223	1	186	4.0e-30	125	COG3658	Cytochrome b	192
643466445	172	28.22	10	172	3	146	5.0e-14	70.8	COG3909	Cytochrome c556	147
643466446	146	42.34	1	136	1	133	3.0e-30	124	COG0848	Biopolymer transport protein ExbD	137
643466447	247	36.41	22	238	1	216	1.0e-36	147	COG0811	Biopolymer transport protein ExbB/TolQ	216
643466449	144	38.19	1	142	2	140	2.0e-30	124	COG1959	DNA-binding transcriptional regulator, IscR family	150
643466451	815	21.44	10	812	7	767	3.0e-31	130	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
643466452	240	24.23	2	227	1	198	2.0e-22	99.7	COG3637	Opacity protein and related surface antigens	199
643466453	233	37.31	28	227	1	180	2.0e-39	155	COG2917	Intracellular septation protein A	180
643466454	232	40.29	27	229	1	206	4.0e-38	151	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
643466455	327	30.9	38	327	11	308	7.0e-25	108	COG3391	DNA-binding beta-propeller fold protein YncE	381
643466456	412	20.77	34	374	2	349	2.0e-09	57.4	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
643466459	631	26.07	8	589	108	733	1.0e-84	307	COG4993	Glucose dehydrogenase	773
643466460	807	15.99	2	772	13	755	6.0e-18	86.5	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
643466465	132	30	24	132	14	123	1.0e-07	49.2	COG1846	DNA-binding transcriptional regulator, MarR family	126
643466466	542	25.79	16	541	2	433	6.0e-111	395	COG2224	Isocitrate lyase	433
643466467	472	43.98	144	470	2	332	6.0e-84	304	COG3800	Predicted transcriptional regulator	332
643466468	255	38.65	13	255	15	263	1.0e-51	196	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
643466469	359	50.98	7	357	1	354	8.0e-99	353	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
643466470	230	30.24	13	216	6	210	3.0e-28	118	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
643466472	643	23.08	11	428	19	400	3.0e-25	110	COG4252	Extracellular (periplasmic) sensor domain CHASE2 (specificity unknown)	400
643466475	286	22.76	1	258	11	300	1.0e-18	87.4	COG1305	Transglutaminase-like enzyme, putative cysteine protease	319
643466478	415	41.45	23	256	8	238	3.0e-62	232	COG3034	Murein L,D-transpeptidase YafK	298
643466479	458	31.74	46	458	1	438	5.0e-61	228	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
643466480	318	37.27	1	318	4	319	1.0e-55	210	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
643466481	810	49.22	40	808	10	781	0.0e+00	946	COG0466	ATP-dependent Lon protease, bacterial type	782
643466482	133	32.84	1	133	1	134	4.0e-16	77	COG0071	Molecular chaperone IbpA, HSP20 family	146
643466485	483	42.59	268	483	20	226	3.0e-62	232	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
643466490	93	48.39	1	88	27	119	8.0e-26	108	COG2343	Uncharacterized conserved protein, DUF427 family	132
643466493	276	32.39	18	158	10	148	7.0e-20	91.3	COG5501	Predicted secreted protein	148
643466494	312	31.83	1	283	2	286	8.0e-35	141	COG0331	Malonyl CoA-acyl carrier protein transacylase	310
643466495	309	35.79	24	288	5	288	5.0e-37	148	COG1767	Triphosphoribosyl-dephospho-CoA synthetase	288
643466504	237	34.25	20	237	12	229	2.0e-31	129	COG1802	DNA-binding transcriptional regulator, GntR family	230
643466507	140	39.29	4	138	9	143	1.0e-23	102	COG1764	Organic hydroperoxide reductase OsmC/OhrA	143
643466508	270	33.46	1	253	4	248	4.0e-46	178	COG3384	Aromatic ring-opening dioxygenase, catalytic subunit, LigB family	268
643466509	186	36.42	1	165	3	175	1.0e-27	116	COG2353	Polyisoprenoid-binding periplasmic protein YceI	192
643466510	197	38.92	3	187	1	178	5.0e-34	137	COG3038	Cytochrome b561	181
643466511	205	39.79	10	199	2	186	2.0e-42	165	COG2353	Polyisoprenoid-binding periplasmic protein YceI	192
643466512	307	26.87	6	296	1	287	4.0e-23	102	COG0583	DNA-binding transcriptional regulator, LysR family	297
643466513	571	25.8	271	527	1	279	3.0e-29	123	COG0515	Serine/threonine protein kinase	384
643466513	571	29.44	14	243	11	255	1.0e-39	158	COG0631	Serine/threonine protein phosphatase PrpC	262
643466514	151	39.07	4	151	1	151	1.0e-16	79.2	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
643466515	208	32.96	27	205	9	184	1.0e-16	80.2	COG3247	Uncharacterized membrane protein HdeD, DUF308 family	185
643466517	152	42.57	8	152	15	159	1.0e-27	115	COG2030	Acyl dehydratase	159
643466518	342	46.2	1	325	1	314	1.0e-83	303	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
643466520	153	31.53	27	134	16	126	1.0e-18	86.1	COG2346	Truncated hemoglobin YjbI	133
643466522	299	31.67	5	299	1	294	3.0e-34	138	COG0583	DNA-binding transcriptional regulator, LysR family	297
643466523	233	33.06	1	233	1	244	1.0e-45	176	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
643466524	199	43	1	199	3	207	2.0e-41	162	COG0655	Multimeric flavodoxin WrbA	207
643466525	133	37.69	1	128	8	137	4.0e-09	53.8	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
643466528	508	39.51	36	115	26	106	6.0e-16	79.2	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
643466529	261	33.2	16	259	2	250	7.0e-37	147	COG2134	CDP-diacylglycerol pyrophosphatase	252
643466530	398	34.85	23	394	3	361	7.0e-79	287	COG1195	Recombinational DNA repair ATPase RecF	363
643466531	483	49.12	151	474	1	340	2.0e-102	366	COG0552	Signal recognition particle GTPase	340
643466532	303	43.67	4	303	1	298	2.0e-79	289	COG0324	tRNA A37 N6-isopentenylltransferase MiaA	308
643466533	319	55.93	7	301	2	294	1.0e-106	379	COG0761	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH	294
643466534	297	28.18	12	297	1	279	9.0e-21	94.4	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
643466538	146	51.03	1	144	8	152	4.0e-41	160	COG0590	tRNA(Arg) A34 adenosine deaminase TadA	152
643466539	252	29.02	1	252	1	233	1.0e-34	140	COG2243	Precorrin-2 methylase	234
643466540	382	27.09	17	363	4	316	2.0e-28	120	COG1275	Tellurite resistance protein TehA and related permeases	329
643466541	306	34.11	1	298	1	295	5.0e-32	131	COG0583	DNA-binding transcriptional regulator, LysR family	297
643466542	616	53.97	1	614	8	575	0.0e+00	775	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
643466543	162	23.97	19	149	14	157	5.0e-07	47.3	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
643466545	631	42.18	50	618	7	566	0.0e+00	466	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
643466546	431	24.45	1	420	28	459	4.0e-47	182	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
643466547	332	25.07	6	331	3	314	1.0e-33	137	COG0451	Nucleoside-diphosphate-sugar epimerase	314
643466549	294	33.82	22	290	11	281	1.0e-35	143	COG1562	Phytoene/squalene synthetase	288
643466550	419	22.25	6	413	3	461	2.0e-19	90.4	COG3349	Uncharacterized conserved protein, contains NAD-binding domain and a Fe-S cluster	485
643466551	672	30.62	109	657	1	510	2.0e-63	237	COG1657	Squalene cyclase	517
643466552	253	23.17	26	165	37	200	1.0e-06	47.3	COG0775	Nucleoside phosphorylase	234
643466553	382	27.74	18	310	9	317	7.0e-25	108	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
643466560	265	32.82	5	264	3	260	2.0e-50	192	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
643466561	467	57.23	1	466	1	463	0.0e+00	596	COG1282	NAD/NADP transhydrogenase beta subunit	463
643466563	448	56.52	2	369	1	356	6.0e-104	371	COG3288	NAD/NADP transhydrogenase alpha subunit	356
643466565	456	30.48	12	426	24	426	3.0e-68	252	COG0661	Predicted unusual protein kinase regulating ubiquinone biosynthesis, AarF/ABC1/UbiB family	517
643466567	445	50.68	8	445	1	438	0.0e+00	483	COG1797	Cobyrinic acid a,c-diamide synthase	451
643466568	253	52.19	1	250	3	252	9.0e-94	336	COG2875	Precorrin-4 methylase	254
643466570	413	44.39	11	212	1	205	1.0e-48	187	COG2241	Precorrin-6B methylase 1	210
643466570	413	45.11	227	407	3	186	7.0e-51	195	COG2242	Precorrin-6B methylase 2	187
643466571	253	49.13	1	221	3	231	2.0e-52	199	COG2099	Precorrin-6x reductase	257
643466572	259	53.01	7	254	1	242	8.0e-82	297	COG1010	Precorrin-3B methylase	249
643466573	247	46.67	9	247	2	234	2.0e-65	242	COG2243	Precorrin-2 methylase	234
643466574	215	57.28	11	215	3	207	4.0e-61	227	COG2082	Precorrin isomerase	210
643466575	423	28.83	2	406	26	461	4.0e-54	205	COG0155	Sulfite reductase, beta subunit (hemoprotein)	510
643466577	349	38.04	12	348	1	319	4.0e-72	265	COG0523	GTPase, G3E family	323
643466579	205	56.06	8	205	2	198	4.0e-64	237	COG2109	ATP:corrinoid adenosyltransferase	198
643466580	480	50.72	1	480	5	485	0.0e+00	562	COG1492	Cobyric acid synthase	486
643466581	330	44.58	2	324	1	314	7.0e-73	267	COG1270	Cobalamin biosynthesis protein CobD/CbiB	320
643466582	352	30.15	41	351	18	348	1.0e-44	174	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
643466583	220	34.72	31	220	1	173	3.0e-37	148	COG1057	Nicotinic acid mononucleotide adenylyltransferase	197
643466584	429	56.22	13	429	1	417	0.0e+00	533	COG0014	Gamma-glutamyl phosphate reductase	417
643466586	327	30.12	14	327	6	327	5.0e-35	141	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
643466587	387	52.43	15	381	2	368	2.0e-118	419	COG0263	Glutamate 5-kinase	369
643466588	346	55.92	1	332	1	338	2.0e-128	452	COG0536	GTPase involved in cell partioning and DNA repair	369
643466589	214	26.78	12	189	4	186	5.0e-17	81.2	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
643466590	91	72.41	1	87	1	87	2.0e-32	130	COG0211	Ribosomal protein L27	87
643466591	125	54.37	1	103	1	103	1.0e-33	134	COG0261	Ribosomal protein L21	103
643466592	665	37.68	421	621	55	259	9.0e-34	139	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
643466595	697	53.07	240	695	1	445	0.0e+00	561	COG3243	Poly(3-hydroxyalkanoate) synthetase	445
643466597	240	55.34	33	238	5	210	5.0e-78	284	COG0177	Endonuclease III	211
643466598	169	39.63	1	164	2	164	6.0e-31	126	COG5488	Uncharacterized membrane protein	164
643466600	239	64.56	1	236	1	220	2.0e-77	282	COG3820	Uncharacterized protein	230
643466602	216	54.29	38	212	1	172	2.0e-65	242	COG0225	Peptide methionine sulfoxide reductase MsrA	174
643466604	307	45.42	1	306	3	276	1.0e-84	306	COG3770	Murein endopeptidase	284
643466606	131	36.61	12	123	11	119	3.0e-09	54.4	COG2363	Uncharacterized membrane protein YgdD, TMEM256/DUF423 family	124
643466608	642	19.24	23	640	1	648	1.0e-19	92.4	COG2982	Uncharacterized protein involved in outer membrane biogenesis	648
643466609	229	27.83	4	214	2	213	2.0e-25	109	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
643466610	250	36.91	21	246	71	298	1.0e-27	117	COG3921	Uncharacterized conserved protein	300
643466611	462	38.16	1	451	2	453	1.0e-121	430	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
643466612	243	29.25	9	219	1	212	5.0e-24	104	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
643466614	376	32.6	10	370	14	370	2.0e-29	123	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
643466615	1049	45.73	1	1027	1	1007	0.0e+00	898	COG0841	Multidrug efflux pump subunit AcrB	1009
643466617	268	56.39	1	264	1	266	6.0e-71	260	COG1659	Uncharacterized protein, linocin/CFP29 family	267
643466618	360	32.81	23	325	25	342	2.0e-65	243	COG2837	Periplasmic deferrochelatase/peroxidase EfeB	352
643466620	209	22.09	25	195	4	174	2.0e-07	49.6	COG1309	DNA-binding transcriptional regulator, AcrR family	201
643466621	320	29.07	19	241	2	214	3.0e-21	96.1	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
643466623	171	31.29	6	166	15	177	3.0e-17	81.7	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
643466624	446	23.83	6	411	1	388	1.0e-30	127	COG3182	Uncharacterized iron-regulated membrane protein	442
643466625	441	37.67	3	425	2	430	7.0e-105	374	COG3486	Lysine/ornithine N-monooxygenase	436
643466626	1343	34.34	247	897	1	642	5.0e-100	360	COG1020	Non-ribosomal peptide synthetase component F	642
643466628	489	30.89	37	469	18	453	2.0e-50	193	COG0534	Na+-driven multidrug efflux pump	455
643466629	392	44.5	18	391	15	396	2.0e-111	396	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
643466630	204	29.41	7	174	11	180	5.0e-15	74.7	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
643466631	745	25.07	42	745	23	750	1.0e-48	188	COG4774	Outer membrane receptor for monomeric catechols	750
643466632	1023	26.31	2	735	1	595	2.0e-94	341	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
643466633	302	42.01	20	237	2	201	3.0e-54	205	COG0437	Fe-S-cluster-containing dehydrogenase component	203
643466634	228	44.44	10	205	9	205	5.0e-45	174	COG2864	Cytochrome b subunit of formate dehydrogenase	218
643466635	309	36.93	21	306	19	303	4.0e-58	218	COG3058	Formate dehydrogenase maturation protein FdhE	308
643466636	350	22.8	59	344	9	315	2.0e-26	113	COG0701	Uncharacterized membrane protein YraQ, UPF0718 family	317
643466637	348	47.37	6	347	6	345	2.0e-105	375	COG0709	Selenophosphate synthase	346
643466639	691	40.89	1	472	1	447	1.0e-107	384	COG3276	Selenocysteine-specific translation elongation factor	447
643466641	469	52.91	73	463	12	395	2.0e-93	336	COG1921	Seryl-tRNA(Sec) selenium transferase	395
643466642	694	33.28	12	667	1	650	7.0e-121	428	COG0210	Superfamily I DNA or RNA helicase	655
643466643	326	46.93	1	324	1	315	1.0e-88	319	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
643466644	188	28.32	13	184	12	182	1.0e-06	46.3	COG3247	Uncharacterized membrane protein HdeD, DUF308 family	185
643466646	314	34.43	9	294	15	344	8.0e-58	217	COG1566	Multidrug resistance efflux pump	352
643466647	299	30.03	4	291	3	287	6.0e-34	138	COG0583	DNA-binding transcriptional regulator, LysR family	297
643466650	688	26.07	8	650	10	645	5.0e-55	209	COG1289	Uncharacterized membrane protein YccC	674
643466655	238	50.77	173	237	1	65	2.0e-10	59.2	COG2771	DNA-binding transcriptional regulator, CsgD family	65
643466660	366	47.04	6	352	2	335	2.0e-111	396	COG0182	Methylthioribose-1-phosphate isomerase (methionine salvage pathway), a paralog of eIF-2B alpha subunit	346
643466664	168	59.52	1	168	26	193	1.0e-56	212	COG3812	Uncharacterized protein	193
643466666	419	28.98	132	407	28	304	1.0e-32	134	COG3509	Poly(3-hydroxybutyrate) depolymerase	312
643466669	210	46.45	1	210	30	237	2.0e-63	235	COG4798	Predicted methyltransferase	238
643466670	137	36.84	1	132	1	133	2.0e-27	114	COG3631	Ketosteroid isomerase-related protein	133
643466671	200	36.97	1	199	2	211	1.0e-38	152	COG2085	Predicted dinucleotide-binding enzyme	211
643466672	250	46.27	3	248	2	251	5.0e-47	181	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
643466673	244	37.85	3	242	2	251	9.0e-39	153	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
643466674	298	28.38	2	288	1	296	2.0e-28	120	COG0583	DNA-binding transcriptional regulator, LysR family	297
643466678	731	20.33	44	730	36	731	1.0e-59	225	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
643466679	155	50.34	5	152	4	151	1.0e-50	192	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
643466680	562	36.08	47	519	1	459	8.0e-83	301	COG2272	Carboxylesterase type B	491
643466682	848	44.35	28	840	97	887	0.0e+00	696	COG3280	Maltooligosyltrehalose synthase	889
643466683	318	32.91	1	236	12	242	3.0e-39	155	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
643466684	650	46.31	29	567	2	542	0.0e+00	500	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
643466685	204	29.65	10	203	12	209	4.0e-18	85	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
643466688	266	27.34	25	263	15	270	1.0e-21	96.9	COG3336	Cytochrome c oxidase assembly factor CtaG	299
643466691	601	29.7	12	566	121	732	9.0e-97	348	COG4993	Glucose dehydrogenase	773
643466692	392	23.85	1	355	2	339	5.0e-23	102	COG0644	Dehydrogenase (flavoprotein)	396
643466694	360	30.35	5	360	2	356	4.0e-59	222	COG3424	Predicted naringenin-chalcone synthase	356
643466696	1044	37.56	2	1015	1	1009	0.0e+00	894	COG0841	Multidrug efflux pump subunit AcrB	1009
643466697	389	31.45	1	368	2	368	2.0e-31	130	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
643466698	426	22.09	10	414	30	445	1.0e-23	104	COG2271	Sugar phosphate permease	448
643466699	260	27.8	8	255	2	258	3.0e-23	102	COG3971	2-keto-4-pentenoate hydratase	264
643466700	402	43.04	10	387	8	383	2.0e-97	349	COG0075	Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism protein PucG	383
643466701	256	33.02	21	235	1	213	9.0e-31	127	COG1802	DNA-binding transcriptional regulator, GntR family	230
643466702	989	24.69	565	966	8	372	3.0e-33	137	COG0247	Fe-S oxidoreductase	388
643466702	989	31.14	18	525	8	458	2.0e-56	214	COG0277	FAD/FMN-containing dehydrogenase	459
643466703	383	33.51	15	379	5	368	6.0e-55	208	COG3616	D-serine deaminase, pyridoxal phosphate-dependent	368
643466708	236	27.31	9	212	4	219	1.0e-24	106	COG1230	Co/Zn/Cd efflux system component	296
643466712	236	39.56	15	233	3	226	7.0e-48	183	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
643466713	1462	29.22	4	1030	1	1008	0.0e+00	640	COG0841	Multidrug efflux pump subunit AcrB	1009
643466713	1462	29.78	1077	1437	9	372	5.0e-27	117	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
643466715	456	27.52	124	447	4	324	1.0e-32	134	COG0642	Signal transduction histidine kinase	336
643466719	205	18.6	6	177	1	169	1.0e-08	53.5	COG1309	DNA-binding transcriptional regulator, AcrR family	201
643466720	401	32.25	62	390	1	327	2.0e-70	259	COG3608	Predicted deacylase	331
643466722	178	29.1	20	150	46	159	1.0e-10	59.6	COG4731	Uncharacterized conserved protein, DUF2147 family	162
643466723	216	25.64	18	212	4	197	1.0e-07	50	COG1309	DNA-binding transcriptional regulator, AcrR family	201
643466724	200	22.81	13	181	4	151	6.0e-08	50.8	COG3637	Opacity protein and related surface antigens	199
643466726	374	40.38	2	367	1	366	3.0e-103	368	COG1062	Zn-dependent alcohol dehydrogenase	366
643466727	507	40.23	1	501	8	527	1.0e-109	390	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
643466728	474	46.19	9	474	1	470	1.0e-129	457	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
643466729	531	43.69	12	531	1	526	0.0e+00	615	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component	526
643466730	626	52.92	1	619	1	641	0.0e+00	737	COG4770	Acetyl/propionyl-CoA carboxylase, alpha subunit	645
643466731	149	40.67	1	149	12	158	4.0e-32	130	COG2030	Acyl dehydratase	159
643466732	278	40.78	5	278	1	277	9.0e-48	183	COG2301	Citrate lyase beta subunit	283
643466734	267	24.45	4	225	3	216	6.0e-17	81.3	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
643466743	368	38.23	11	368	11	367	6.0e-54	205	COG0387	Ca2+/H+ antiporter	368
643466745	380	41.57	22	364	12	345	3.0e-77	282	COG1566	Multidrug resistance efflux pump	352
643466747	303	49.62	1	257	1	261	2.0e-88	319	COG0708	Exonuclease III	261
643466748	322	46.75	4	318	1	323	1.0e-85	309	COG0523	GTPase, G3E family	323
643466756	327	39.24	2	315	12	324	1.0e-64	240	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
643466758	265	39.75	18	243	14	252	2.0e-61	228	COG1120	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	258
643466759	339	41.59	5	336	5	334	6.0e-49	188	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
643466760	508	21.55	107	508	49	451	2.0e-18	87.8	COG2710	Nitrogenase molybdenum-iron protein, alpha and beta chains	456
643466761	728	21.17	5	728	1	719	3.0e-34	140	COG4773	Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid	719
643466763	364	25.31	9	317	7	319	1.0e-23	104	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
643466765	836	33.84	570	827	84	336	3.0e-36	147	COG0642	Signal transduction histidine kinase	336
643466767	164	33.33	6	146	4	142	1.0e-25	109	COG2001	MraZ, DNA-binding transcriptional regulator and inhibitor of RsmH methyltransferase activity	146
643466768	346	52.06	14	323	2	314	5.0e-103	367	COG0275	16S rRNA C1402 N4-methylase RsmH	314
643466770	599	33.39	40	572	12	599	1.0e-98	354	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
643466771	490	42.4	20	481	9	473	2.0e-112	400	COG0769	UDP-N-acetylmuramyl tripeptide synthase	475
643466772	498	40.48	24	485	2	449	4.0e-112	398	COG0770	UDP-N-acetylmuramyl pentapeptide synthase	451
643466773	360	45.11	19	360	1	316	1.0e-55	210	COG0472	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase	319
643466774	461	41.94	7	459	5	448	8.0e-112	397	COG0771	UDP-N-acetylmuramoylalanine-D-glutamate ligase	448
643466775	130	39.85	1	130	3	133	6.0e-17	80	COG4113	Predicted nucleic acid-binding protein, contains PIN domain	134
643466777	398	36.49	13	369	10	376	7.0e-67	248	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
643466778	371	38.4	5	363	1	355	2.0e-76	279	COG0707	UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase	357
643466779	468	50.64	1	465	1	459	0.0e+00	584	COG0773	UDP-N-acetylmuramate-alanine ligase	459
643466780	315	44.76	21	303	3	288	6.0e-83	300	COG0812	UDP-N-acetylenolpyruvoylglucosamine reductase	291
643466781	125	38.75	9	88	6	83	2.0e-15	74.6	COG2827	Predicted endonuclease, GIY-YIG superfamily	95
643466783	307	41.61	1	304	1	317	6.0e-79	287	COG1181	D-alanine-D-alanine ligase and related ATP-grasp enzymes	317
643466784	326	25.44	40	315	1	269	3.0e-26	112	COG1589	Cell division septal protein FtsQ	269
643466785	438	41.72	15	438	2	418	2.0e-109	389	COG0849	Cell division ATPase FtsA	418
643466786	569	56.29	7	340	4	334	3.0e-110	392	COG0206	Cell division GTPase FtsZ	338
643466787	288	42.24	39	270	23	254	4.0e-60	225	COG4105	Outer membrane protein assembly factor BamD, BamD/ComL family	254
643466788	553	42.11	1	553	1	556	0.0e+00	508	COG0497	DNA repair ATPase RecN	557
643466789	540	30.35	44	370	1	326	4.0e-21	96.4	COG3391	DNA-binding beta-propeller fold protein YncE	381
643466790	700	56.85	8	698	1	667	0.0e+00	892	COG0272	NAD-dependent DNA ligase	667
643466791	339	30.7	3	327	1	293	2.0e-38	152	COG2159	Predicted metal-dependent hydrolase, TIM-barrel fold	293
643466792	598	22.26	58	584	6	475	6.0e-45	175	COG3119	Arylsulfatase A or related enzyme	475
643466794	198	21.8	44	175	2	126	6.0e-09	54.1	COG0526	Thiol-disulfide isomerase or thioredoxin	127
643466796	254	43.23	4	231	41	269	5.0e-40	158	COG0755	ABC-type transport system involved in cytochrome c biogenesis, permease component	281
643466798	239	55.14	22	235	6	217	1.0e-38	153	COG2386	ABC-type transport system involved in cytochrome c biogenesis, permease component	221
643466799	202	40	2	202	1	204	2.0e-48	185	COG4133	ABC-type transport system involved in cytochrome c biogenesis, ATPase component	209
643466800	910	63.04	7	907	1	859	0.0e+00	1227	COG1048	Aconitase A	861
643466801	370	52.97	1	366	1	346	2.0e-118	419	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
643466805	357	53.41	15	345	1	334	2.0e-115	409	COG0136	Aspartate-semialdehyde dehydrogenase	334
643466807	330	35.48	207	329	2	121	1.0e-14	74.1	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
643466809	355	34.72	6	342	2	329	3.0e-62	232	COG3768	Uncharacterized membrane protein YcjF, UPF0283 family	350
643466810	500	42.91	10	499	4	466	0.0e+00	479	COG3106	Predicted ATPase, YcjX-like family	467
643466812	175	34.13	1	166	1	161	2.0e-23	101	COG2062	Phosphohistidine phosphatase SixA	163
643466814	895	53.79	1	891	5	878	0.0e+00	1114	COG0013	Alanyl-tRNA synthetase	879
643466815	355	66.67	15	293	6	279	4.0e-88	318	COG0468	RecA/RadA recombinase	279
643466818	839	26.42	357	699	3	336	8.0e-37	149	COG0642	Signal transduction histidine kinase	336
643466820	139	56.67	19	138	1	120	2.0e-27	114	COG1734	RNA polymerase-binding transcription factor DksA	120
643466821	407	33.25	1	399	14	407	6.0e-128	450	COG0538	Isocitrate dehydrogenase	407
643466824	520	24.8	1	485	2	432	2.0e-36	147	COG3025	Inorganic triphosphatase YgiF, contains CYTH and CHAD domains	432
643466826	174	53.33	4	167	9	173	4.0e-46	177	COG3703	Cation transport regulator ChaC	190
643466827	350	17.48	4	349	7	338	2.0e-13	70.8	COG4093	Uncharacterized protein	338
643466828	488	48.15	272	486	14	223	2.0e-63	237	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
643466829	648	54.65	34	645	1	589	0.0e+00	745	COG0441	Threonyl-tRNA synthetase	589
643466830	229	36.67	169	228	2	61	6.0e-07	48.1	COG2771	DNA-binding transcriptional regulator, CsgD family	65
643466832	250	26.38	7	236	1	230	9.0e-26	110	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
643466835	306	47.9	19	298	14	291	5.0e-75	274	COG0685	5,10-methylenetetrahydrofolate reductase	291
643466836	1245	58.36	7	332	1	311	7.0e-113	402	COG0646	Methionine synthase I (cobalamin-dependent), methyltransferase domain	311
643466836	1245	59.36	333	1201	1	842	0.0e+00	1143	COG1410	Methionine synthase I, cobalamin-binding domain	842
643466837	255	45.31	7	249	17	255	1.0e-66	246	COG3023	N-acetyl-anhydromuramyl-L-alanine amidase AmpD	257
643466840	106	43.4	1	105	1	102	5.0e-15	72.8	COG0633	Ferredoxin	102
643466841	345	29.54	8	326	5	305	8.0e-52	197	COG0492	Thioredoxin reductase	305
643466842	167	51.22	1	164	1	159	1.0e-54	205	COG0669	Phosphopantetheine adenylyltransferase	159
643466843	186	52.6	31	177	1	154	3.0e-47	181	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
643466844	151	50	7	150	1	156	2.0e-46	178	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
643466845	361	52.37	1	358	1	348	1.0e-127	450	COG0809	S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase)	348
643466846	378	55.11	7	378	1	372	0.0e+00	496	COG0343	Queuine/archaeosine tRNA-ribosyltransferase	372
643466847	215	32.02	2	200	1	200	4.0e-29	121	COG0625	Glutathione S-transferase	211
643466848	367	40.44	10	367	1	351	3.0e-88	319	COG3049	Penicillin V acylase or related amidase, Ntn superfamily	353
643466849	400	44.51	7	328	14	341	2.0e-69	256	COG2951	Membrane-bound lytic murein transglycosylase B	343
643466850	1047	47.04	1	1026	1	1007	0.0e+00	930	COG0841	Multidrug efflux pump subunit AcrB	1009
643466851	393	26.87	1	384	4	372	1.0e-24	107	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
643466853	259	52.77	26	259	1	232	3.0e-85	307	COG0479	Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit	234
643466854	612	53.44	21	594	1	560	0.0e+00	626	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
643466855	129	26.13	17	127	7	117	1.0e-13	68.7	COG2142	Succinate dehydrogenase, hydrophobic anchor subunit	117
643466856	131	44.35	7	125	1	124	1.0e-15	75.3	COG2009	Succinate dehydrogenase/fumarate reductase, cytochrome b subunit	132
643466857	331	27.9	29	331	1	309	3.0e-29	122	COG3509	Poly(3-hydroxybutyrate) depolymerase	312
643466858	118	39.39	14	111	5	100	2.0e-16	77.7	COG1872	Uncharacterized conserved protein YggU, UPF0235/DUF167 family	102
643466862	647	28.3	3	470	14	419	1.0e-54	208	COG0286	Type I restriction-modification system, DNA methylase subunit	489
643466863	458	17.94	26	416	1	391	3.0e-13	70.5	COG0732	Restriction endonuclease S subunit	391
643466866	976	24.26	40	820	15	755	4.0e-100	359	COG0610	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases ...	962
643466868	242	33.47	1	241	5	249	2.0e-35	142	COG1484	DNA replication protein DnaC	254
643466873	274	30.31	1	274	1	281	4.0e-30	125	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
643466876	414	22	14	405	15	406	4.0e-60	225	COG4320	Uncharacterized conserved protein, DUF2252 family	410
643466877	746	33.78	10	746	6	726	0.0e+00	483	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
643466878	338	38.86	1	327	1	282	5.0e-63	234	COG1319	CO or xanthine dehydrogenase, FAD-binding subunit	284
643466879	179	60.93	14	163	1	151	1.0e-54	205	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
643466880	650	32.2	28	262	1	232	7.0e-15	76.2	COG2202	PAS domain	232
643466881	360	32.4	79	358	11	293	6.0e-42	165	COG1295	Uncharacterized membrane protein, BrkB/YihY/UPF0761 family (not an RNase)	303
643466882	385	27.32	15	346	13	364	1.0e-22	101	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
643466883	246	26.69	17	244	3	227	2.0e-20	93.2	COG2120	N-acetylglucosaminyl deacetylase, LmbE family	237
643466886	694	56.85	27	522	11	496	0.0e+00	704	COG0753	Catalase	496
643466887	575	32.32	52	534	3	458	5.0e-82	298	COG2272	Carboxylesterase type B	491
643466888	584	22.57	18	397	27	368	4.0e-15	76.9	COG1680	CubicO group peptidase, beta-lactamase class C family	390
643466891	761	31.7	125	383	7	263	1.0e-51	198	COG3665	Uncharacterized conserved protein YcgI, DUF1989 family	264
643466891	761	39.12	384	761	3	379	6.0e-91	329	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
643466892	451	28.42	1	450	8	438	6.0e-71	261	COG2072	Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD	443
643466893	378	35.47	8	370	6	378	2.0e-71	263	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
643466894	571	19.56	26	520	21	449	2.0e-19	91	COG0531	Amino acid transporter	466
643466896	317	31.84	8	256	7	266	2.0e-39	156	COG1018	Ferredoxin-NADP reductase	266
643466899	262	34.21	4	188	3	192	1.0e-33	136	COG0300	Short-chain dehydrogenase	265
643466900	307	28.52	8	300	5	297	2.0e-28	120	COG0583	DNA-binding transcriptional regulator, LysR family	297
643466901	97	47.83	7	97	8	99	2.0e-29	120	COG2440	Ferredoxin-like protein FixX	99
643466902	435	30.41	3	434	1	396	3.0e-65	242	COG0644	Dehydrogenase (flavoprotein)	396
643466903	368	44.07	29	357	1	313	5.0e-94	337	COG2025	Electron transfer flavoprotein, alpha subunit	313
643466904	283	46.35	1	272	1	260	9.0e-68	250	COG2086	Electron transfer flavoprotein, alpha and beta subunits	260
643466906	251	50.25	14	212	1	194	1.0e-61	230	COG1045	Serine acetyltransferase	194
643466907	390	37.96	8	380	3	384	2.0e-82	299	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
643466908	400	54.12	2	386	1	386	0.0e+00	493	COG1104	Cysteine sulfinate desulfinase/cysteine desulfurase or related enzyme	386
643466909	344	32.1	256	332	4	84	2.0e-08	53.8	COG0694	Fe-S cluster biogenesis protein NfuA, 4Fe-4S-binding domain	93
643466909	344	44.6	13	132	7	143	6.0e-29	121	COG0822	NifU homolog involved in Fe-S cluster formation	150
643466910	106	49.06	1	106	4	109	6.0e-32	128	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
643466913	66	48.48	1	66	5	70	3.0e-11	60.1	COG5420	Uncharacterized protein	71
643466916	464	29.98	3	443	19	450	6.0e-70	258	COG2710	Nitrogenase molybdenum-iron protein, alpha and beta chains	456
643466917	482	34.6	1	464	1	455	5.0e-96	345	COG2710	Nitrogenase molybdenum-iron protein, alpha and beta chains	456
643466918	519	30.94	37	515	5	453	4.0e-90	325	COG2710	Nitrogenase molybdenum-iron protein, alpha and beta chains	456
643466919	488	35.91	29	486	1	447	1.0e-104	373	COG2710	Nitrogenase molybdenum-iron protein, alpha and beta chains	456
643466920	293	69.82	4	277	1	274	3.0e-117	415	COG1348	Nitrogenase subunit NifH, an ATPase	278
643466925	382	36.02	6	371	6	370	2.0e-75	276	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
643466927	67	56.92	1	65	4	67	2.0e-16	77.4	COG5554	Nitrogen fixation protein	69
643466932	118	36.54	1	103	3	106	3.0e-19	87.2	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
643466934	519	20.89	63	351	6	268	2.0e-24	107	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
643466936	576	41.62	6	576	11	550	0.0e+00	524	COG3604	Transcriptional regulator containing GAF, AAA-type ATPase, and DNA-binding Fis domains	550
643466938	141	37.7	13	134	10	128	1.0e-24	105	COG2346	Truncated hemoglobin YjbI	133
643466939	158	30.23	24	150	6	133	1.0e-25	109	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
643466940	134	53.24	1	134	3	130	1.0e-36	145	COG1970	Large-conductance mechanosensitive channel	130
643466942	161	38.67	12	161	9	158	4.0e-42	163	COG1905	NADH:ubiquinone oxidoreductase 24 kD subunit (chain E)	160
643466943	516	53.7	93	510	1	419	0.0e+00	577	COG1894	NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F)	424
643466944	948	47.32	15	948	1	972	0.0e+00	1266	COG3383	Predicted molibdopterin-dependent oxidoreductase YjgC	978
643466945	285	43.9	33	278	22	266	6.0e-65	240	COG1526	Formate dehydrogenase assembly factor FdhD	266
643466947	557	65.35	73	552	1	482	0.0e+00	663	COG3278	Cbb3-type cytochrome oxidase, subunit 1	482
643466948	255	58.12	18	251	3	227	1.0e-89	322	COG2993	Cbb3-type cytochrome oxidase, cytochrome c subunit	227
643466949	50	47.92	3	50	2	49	2.0e-07	47.5	COG4736	Cbb3-type cytochrome oxidase, subunit 3	60
643466950	294	29.75	64	219	3	147	4.0e-13	68.8	COG2010	Cytochrome c, mono- and diheme variants	150
643466951	492	31.35	35	419	1	354	3.0e-66	246	COG0348	Polyferredoxin	386
643466952	169	28.48	12	169	10	162	1.0e-21	96.2	COG5456	Nitrogen fixation protein FixH	166
643466953	749	38.67	20	728	3	713	0.0e+00	537	COG2217	Cation transport ATPase	713
643466954	49	55.1	1	49	1	49	5.0e-11	59.5	COG3197	Uncharacterized protein, possibly involved in nitrogen fixation	58
643466958	879	65.21	137	800	1	663	0.0e+00	1097	COG0556	Excinuclease UvrABC helicase subunit UvrB	663
643466961	272	36.88	10	259	14	276	2.0e-42	166	COG2951	Membrane-bound lytic murein transglycosylase B	343
643466964	181	43.83	11	170	10	168	3.0e-39	155	COG0521	Molybdopterin biosynthesis enzyme MoaB	169
643466965	839	27.85	524	827	1	311	6.0e-36	146	COG2307	Uncharacterized conserved protein, Alpha-E superfamily	313
643466965	839	42.2	34	510	13	488	0.0e+00	523	COG2308	Uncharacterized conserved protein, circularly permuted ATPgrasp superfamily	488
643466966	299	32.47	1	297	11	316	2.0e-35	143	COG1305	Transglutaminase-like enzyme, putative cysteine protease	319
643466967	97	50.52	1	97	8	104	6.0e-29	118	COG4274	Uncharacterized protein, contains GYD domain	104
643466968	230	32.08	2	211	1	201	9.0e-21	93.7	COG0625	Glutathione S-transferase	211
643466969	366	49.52	14	326	32	337	3.0e-92	331	COG1600	Epoxyqueuosine reductase  QueG (queuosine biosynthesis)	337
643466970	291	22.79	7	268	8	289	9.0e-14	71.1	COG0451	Nucleoside-diphosphate-sugar epimerase	314
643466971	315	30.03	3	302	1	297	2.0e-31	129	COG0583	DNA-binding transcriptional regulator, LysR family	297
643466972	331	37.74	1	316	1	316	6.0e-70	257	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
643466973	709	32.8	4	706	10	740	6.0e-124	438	COG4251	Bacteriophytochrome (light-regulated signal transduction histidine kinase)	750
643466974	689	46.55	10	683	5	682	0.0e+00	760	COG0339	Zn-dependent oligopeptidase	683
643466975	211	25.94	3	207	34	244	7.0e-20	90.7	COG1651	Protein-disulfide isomerase	244
643466976	166	40.96	1	166	1	142	3.0e-30	124	COG5319	Uncharacterized protein	142
643466977	87	50	2	79	1	80	4.0e-21	93.1	COG0695	Glutaredoxin	80
643466978	158	30.89	34	152	12	133	6.0e-18	83.8	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
643466979	348	42.77	15	346	2	320	4.0e-100	358	COG0276	Protoheme ferro-lyase (ferrochelatase)	320
643466981	279	43.66	6	269	3	269	7.0e-80	290	COG3220	Uncharacterized conserved protein, UPF0276 family	282
643466983	329	55.35	1	326	1	327	0.0e+00	473	COG1087	UDP-glucose 4-epimerase	329
643466984	295	54.45	2	292	1	287	3.0e-113	401	COG1210	UTP-glucose-1-phosphate uridylyltransferase	291
643466985	364	44.14	8	361	6	358	3.0e-94	338	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
643466986	84	66.67	9	83	10	84	2.0e-17	81.1	COG3750	Uncharacterized conserved protein, UPF0335 family	85
643466987	274	50.58	12	268	7	263	3.0e-75	274	COG3931	Predicted N-formylglutamate amidohydrolase	263
643466988	143	38.03	1	138	7	147	9.0e-30	122	COG5480	Uncharacterized membrane protein	147
643466989	497	47.47	1	467	1	474	0.0e+00	541	COG0469	Pyruvate kinase	477
643466990	712	43.54	18	676	3	661	0.0e+00	564	COG0744	Membrane carboxypeptidase (penicillin-binding protein)	661
643466992	372	42.2	1	372	1	364	6.0e-90	324	COG0592	DNA polymerase III sliding clamp (beta) subunit, PCNA homolog	364
643466994	129	24.06	1	129	3	131	2.0e-07	48.6	COG1487	Predicted nucleic acid-binding protein, contains PIN domain	133
643466995	70	47.46	1	58	15	73	1.0e-06	45	COG5450	Transcription regulator of the Arc/MetJ class	84
643466996	189	43.51	1	131	1	131	4.0e-38	151	COG0231	Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)	131
643466997	263	44.06	3	261	1	260	3.0e-71	261	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
643467001	288	33.73	5	241	1	247	5.0e-24	105	COG0583	DNA-binding transcriptional regulator, LysR family	297
643467002	343	36.2	6	331	3	316	9.0e-56	210	COG0385	Predicted Na+-dependent transporter	319
643467005	341	33.33	7	333	106	423	2.0e-50	192	COG1793	ATP-dependent DNA ligase	444
643467006	241	49.76	14	224	1	208	7.0e-61	227	COG2258	Uncharacterized conserved protein YiiM, contains MOSC domain	210
643467007	196	23.28	1	184	8	196	4.0e-08	51.6	COG1309	DNA-binding transcriptional regulator, AcrR family	201
643467008	176	29.01	15	176	17	176	3.0e-28	118	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
643467009	884	21.2	245	435	22	236	7.0e-07	50	COG0412	Dienelactone hydrolase	236
643467009	884	34.97	441	868	2	404	2.0e-81	298	COG2312	Erythromycin esterase homolog	405
643467009	884	53.42	8	225	4	220	4.0e-59	223	COG1926	Predicted phosphoribosyltransferase	220
643467010	309	54.22	1	307	3	309	9.0e-116	409	COG2066	Glutaminase	309
643467012	653	41.74	9	646	8	605	0.0e+00	534	COG3284	Transcriptional regulator of acetoin/glycerol metabolism	606
643467013	358	20.97	3	309	2	317	3.0e-18	86.2	COG3199	Predicted polyphosphate- or ATP-dependent NAD kinase	355
643467014	327	45.37	7	327	23	345	7.0e-96	344	COG1071	TPP-dependent pyruvate or acetoin dehydrogenase subunit alpha	358
643467015	340	52.71	4	333	1	322	7.0e-123	433	COG0022	Pyruvate/2-oxoglutarate/acetoin dehydrogenase complex, dehydrogenase (E1) component	324
643467016	372	28.16	115	368	3	277	1.0e-25	110	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
643467018	562	26.15	5	533	115	719	1.0e-64	241	COG4993	Glucose dehydrogenase	773
643467019	132	28.04	25	130	29	134	5.0e-07	46.9	COG2010	Cytochrome c, mono- and diheme variants	150
643467022	197	28.88	12	191	1	187	3.0e-23	101	COG2059	Chromate transport protein ChrA	195
643467023	175	30	8	175	10	179	9.0e-21	93.4	COG2059	Chromate transport protein ChrA	195
643467024	190	59.16	1	189	6	194	3.0e-69	254	COG0302	GTP cyclohydrolase I	195
643467027	236	24.76	9	211	5	214	1.0e-17	83.7	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
643467029	247	27.4	8	208	5	212	5.0e-18	84.9	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
643467030	201	20.53	10	199	7	196	1.0e-07	49.6	COG1309	DNA-binding transcriptional regulator, AcrR family	201
643467032	199	51.24	1	199	5	201	7.0e-23	100	COG2370	Hydrogenase/urease accessory protein HupE	201
643467033	319	41.06	112	314	1	200	2.0e-57	216	COG0378	Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase	202
643467034	112	39.47	1	110	1	114	8.0e-23	98.8	COG0375	Zn finger protein HypA/HybF (possibly regulating hydrogenase expression)	115
643467035	355	51.59	20	355	3	339	5.0e-94	337	COG0309	Hydrogenase maturation factor	339
643467036	385	53.24	1	369	1	363	0.0e+00	502	COG0409	Hydrogenase maturation factor	364
643467037	93	53.01	1	83	1	77	4.0e-19	86.1	COG0298	Hydrogenase maturation factor	82
643467038	809	44.15	16	799	1	750	0.0e+00	779	COG0068	Hydrogenase maturation factor HypF (carbamoyltransferase)	750
643467040	290	33.98	190	289	4	106	2.0e-12	66.9	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
643467040	290	37.8	92	170	8	89	9.0e-14	71.1	COG0694	Fe-S cluster biogenesis protein NfuA, 4Fe-4S-binding domain	93
643467045	158	27.27	1	153	3	155	1.0e-24	105	COG0680	Ni,Fe-hydrogenase maturation factor	160
643467048	532	29.22	6	531	2	545	0.0e+00	474	COG0374	Ni,Fe-hydrogenase I large subunit	545
643467049	320	32.42	1	316	48	355	5.0e-85	308	COG1740	Ni,Fe-hydrogenase I small subunit	355
643467051	481	38.51	8	477	7	456	1.0e-97	350	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
643467052	780	40.35	5	613	86	712	3.0e-130	459	COG2217	Cation transport ATPase	713
643467053	195	34.92	1	189	4	192	1.0e-32	132	COG3707	Two-component response regulator, AmiR/NasT family, consists of REC and RNA-binding antiterminator (ANTAR) domains	194
643467054	407	27.76	8	329	20	333	2.0e-34	139	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
643467055	300	47.5	49	288	5	241	6.0e-65	241	COG0007	Uroporphyrinogen-III methylase (siroheme synthase)	244
643467056	404	38.69	1	398	2	412	6.0e-77	281	COG2223	Nitrate/nitrite transporter NarK	417
643467059	813	46.89	1	804	1	789	0.0e+00	892	COG1251	NAD(P)H-nitrite reductase, large subunit	793
643467060	107	35.85	1	104	2	106	6.0e-20	89.3	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
643467061	247	43.15	6	246	4	250	2.0e-42	165	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
643467062	371	34.83	1	367	1	374	6.0e-79	287	COG0579	L-2-hydroxyglutarate oxidase LhgO	429
643467063	122	25.86	1	116	1	97	2.0e-07	48.1	COG0633	Ferredoxin	102
643467065	311	51.74	1	311	1	312	9.0e-81	293	COG2025	Electron transfer flavoprotein, alpha subunit	313
643467066	249	50.38	1	249	1	260	1.0e-64	240	COG2086	Electron transfer flavoprotein, alpha and beta subunits	260
643467067	225	22.99	13	194	4	190	6.0e-08	51.2	COG1309	DNA-binding transcriptional regulator, AcrR family	201
643467069	736	52.21	581	716	8	143	1.0e-38	155	COG2185	Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding)	143
643467069	736	60	13	548	8	546	0.0e+00	698	COG1884	Methylmalonyl-CoA mutase, N-terminal domain/subunit	548
643467071	668	53.51	1	668	1	645	0.0e+00	795	COG4770	Acetyl/propionyl-CoA carboxylase, alpha subunit	645
643467072	510	55.49	1	510	11	526	0.0e+00	672	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component	526
643467073	477	46.69	142	473	1	331	4.0e-98	352	COG3800	Predicted transcriptional regulator	332
643467074	390	29.18	155	386	52	282	7.0e-15	75.3	COG0842	ABC-type multidrug transport system, permease component	286
643467075	912	30.33	13	491	16	519	5.0e-72	266	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
643467077	190	34.52	1	186	1	196	7.0e-22	97	COG4094	Uncharacterized membrane protein	219
643467078	717	50.49	4	712	6	694	0.0e+00	792	COG1523	Pullulanase/glycogen debranching enzyme	697
643467079	294	36.39	1	290	1	290	2.0e-35	143	COG0583	DNA-binding transcriptional regulator, LysR family	297
643467080	135	37.61	19	135	8	124	5.0e-19	86.7	COG1380	Putative effector of murein hydrolase LrgA, UPF0299 family	128
643467081	240	48.44	10	234	2	226	1.0e-58	219	COG1346	Putative effector of murein hydrolase	230
643467082	128	57.66	9	119	1	111	3.0e-34	137	COG3502	Uncharacterized conserved protein, DUF952 family	115
643467083	585	35.79	37	568	3	521	0.0e+00	500	COG1384	Lysyl-tRNA synthetase, class I	521
643467084	297	37.64	43	295	8	249	3.0e-51	195	COG2857	Cytochrome c1	250
643467085	417	49.6	7	381	1	371	1.0e-94	340	COG1290	Cytochrome b subunit of the bc complex	381
643467086	173	41.32	9	173	8	166	2.0e-36	145	COG0723	Rieske Fe-S protein	177
643467087	169	43.92	9	155	3	149	2.0e-45	174	COG0219	tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain	155
643467089	298	47.16	8	298	4	279	1.0e-100	359	COG0408	Coproporphyrinogen III oxidase	303
643467091	233	42.5	41	200	22	181	4.0e-36	144	COG2091	Phosphopantetheinyl transferase	223
643467092	374	43.08	50	360	1	306	6.0e-76	277	COG0167	Dihydroorotate dehydrogenase	310
643467094	206	48.91	3	206	2	230	5.0e-73	267	COG0588	Phosphoglycerate mutase (BPG-dependent)	230
643467095	216	45.1	3	206	2	194	5.0e-39	154	COG3145	Alkylated DNA repair dioxygenase AlkB	194
643467096	279	35.23	1	276	3	265	2.0e-45	176	COG0388	Predicted amidohydrolase	274
643467097	528	36.15	1	514	5	546	5.0e-104	372	COG4166	ABC-type oligopeptide transport system, periplasmic component	562
643467098	195	55.61	1	195	1	184	3.0e-59	221	COG2096	Cob(I)alamin adenosyltransferase	184
643467101	422	47.24	1	394	1	394	7.0e-120	424	COG0019	Diaminopimelate decarboxylase	394
643467103	283	26.4	1	278	11	313	1.0e-28	120	COG1305	Transglutaminase-like enzyme, putative cysteine protease	319
643467104	160	30.92	7	158	11	161	2.0e-10	58.7	COG0711	FoF1-type ATP synthase, membrane subunit b or b'	161
643467105	183	28.48	33	183	6	156	9.0e-15	73.4	COG0711	FoF1-type ATP synthase, membrane subunit b or b'	161
643467107	250	36.61	1	249	1	246	2.0e-39	156	COG0356	FoF1-type ATP synthase, membrane subunit a	246
643467108	144	40.62	45	140	9	100	2.0e-13	68.1	COG5336	FoF1-type ATP synthase assembly protein I	116
643467109	1151	32.55	1	1148	1	1163	0.0e+00	554	COG1196	Chromosome segregation ATPase	1163
643467110	217	33.8	4	217	1	216	6.0e-36	144	COG2761	Predicted dithiol-disulfide isomerase, DsbA family	225
643467111	610	28.43	7	608	1	557	1.0e-87	317	COG4166	ABC-type oligopeptide transport system, periplasmic component	562
643467113	187	29.41	4	139	44	178	2.0e-21	95.4	COG5342	Invasion protein IalB, involved in pathogenesis	181
643467114	211	34.47	6	208	2	207	2.0e-36	146	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
643467116	252	55.36	21	252	6	238	4.0e-81	294	COG0528	Uridylate kinase	238
643467117	186	51.08	1	186	2	187	1.0e-61	228	COG0233	Ribosome recycling factor	187
643467118	260	50.64	17	249	13	245	7.0e-80	290	COG0020	Undecaprenyl pyrophosphate synthase	245
643467119	300	28.96	31	281	1	259	1.0e-31	130	COG0575	CDP-diglyceride synthetase	265
643467120	412	48.59	23	410	2	385	8.0e-121	427	COG0743	1-deoxy-D-xylulose 5-phosphate reductoisomerase	385
643467121	381	42.74	13	375	4	375	2.0e-61	230	COG0750	Membrane-associated protease RseP, regulator of RpoE activity	375
643467122	821	35.87	19	821	11	766	0.0e+00	594	COG4775	Outer membrane protein assembly factor BamA	766
643467123	349	39.34	11	339	2	326	1.0e-65	244	COG1044	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase	338
643467124	157	44.22	8	152	1	145	1.0e-42	165	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
643467125	323	46.18	3	323	2	326	1.0e-74	273	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
643467126	247	28.92	1	240	4	251	1.0e-36	147	COG1381	Recombinational DNA repair protein (RecF pathway)	251
643467127	55	58.7	8	53	5	50	4.0e-08	49.4	COG0267	Ribosomal protein L33	50
643467128	397	25.26	24	397	14	394	2.0e-09	57.5	COG2807	Cyanate permease	395
643467129	163	46.72	16	137	5	125	4.0e-33	134	COG5349	Uncharacterized conserved protein, DUF983 family	126
643467130	133	30.71	5	128	11	137	3.0e-19	87.3	COG3439	Uncharacterized conserved protein, DUF302 family	137
643467131	787	38.23	36	763	5	704	0.0e+00	565	COG0557	Exoribonuclease R	706
643467132	977	49.49	1	587	1	569	0.0e+00	634	COG0550	DNA topoisomerase IA	570
643467133	316	49.19	10	309	5	310	4.0e-106	378	COG0540	Aspartate carbamoyltransferase, catalytic chain	316
643467134	439	41.72	12	439	1	423	1.0e-106	380	COG0044	Dihydroorotase or related cyclic amidohydrolase	430
643467138	482	32.73	297	459	11	175	1.0e-28	121	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
643467139	112	63.39	1	112	1	112	6.0e-34	135	COG0347	Nitrogen regulatory protein PII	112
643467140	466	54.61	57	463	2	399	3.0e-117	415	COG0004	Ammonia channel protein AmtB	409
643467141	204	46.12	1	202	2	200	2.0e-40	158	COG0344	Phospholipid biosynthesis protein PlsY, probable glycerol-3-phosphate acyltransferase	200
643467142	422	43.19	7	302	1	301	1.0e-77	283	COG0758	Predicted Rossmann fold nucleotide-binding protein DprA/Smf involved in DNA uptake	350
643467143	452	63.7	1	447	1	449	0.0e+00	596	COG0439	Biotin carboxylase	449
643467144	152	36.99	22	152	1	139	2.0e-19	88.6	COG0511	Biotin carboxyl carrier protein	140
643467145	148	56.74	2	142	1	141	1.0e-52	198	COG0757	3-dehydroquinate dehydratase	146
643467147	63	41.82	3	57	19	73	4.0e-08	49.6	COG0690	Preprotein translocase subunit SecE	73
643467148	176	51.41	1	176	1	177	2.0e-50	192	COG0250	Transcription antitermination factor NusG	178
643467149	142	60.99	2	142	1	140	1.0e-49	188	COG0080	Ribosomal protein L11	141
643467150	231	64.04	1	227	1	228	4.0e-81	294	COG0081	Ribosomal protein L1	228
643467151	171	44.51	1	171	3	175	3.0e-34	138	COG0244	Ribosomal protein L10	175
643467152	126	68.25	1	126	2	124	3.0e-21	94.2	COG0222	Ribosomal protein L7/L12	124
643467154	1397	49.12	21	848	7	807	0.0e+00	869	COG0086	DNA-directed RNA polymerase, beta' subunit/160 kD subunit	808
643467156	690	34.29	19	390	10	372	1.0e-57	218	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
643467159	472	43.6	22	469	1	455	0.0e+00	507	COG0493	NADPH-dependent glutamate synthase beta chain or related oxidoreductase	457
643467160	1566	59.27	731	1223	1	482	0.0e+00	653	COG0069	Glutamate synthase domain 2	485
643467161	350	40.11	1	349	1	338	9.0e-86	310	COG2008	Threonine aldolase	342
643467162	159	37.76	1	141	7	145	1.0e-28	119	COG0071	Molecular chaperone IbpA, HSP20 family	146
643467163	345	29.45	29	332	6	297	4.0e-45	175	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
643467165	409	32.8	47	351	46	353	8.0e-52	197	COG2845	Uncharacterized protein	354
643467166	507	49.79	28	507	3	470	0.0e+00	486	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
643467167	573	41.39	30	568	16	553	2.0e-108	386	COG0659	Sulfate permease or related transporter, MFS superfamily	554
643467169	249	32.39	1	245	4	246	5.0e-39	154	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
643467178	406	19.2	10	405	9	408	6.0e-15	75.7	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
643467179	222	45.25	1	220	1	220	2.0e-65	241	COG1136	ABC-type lipoprotein export system, ATPase component	226
643467182	429	27.05	5	410	4	397	2.0e-36	146	COG1819	UDP:flavonoid glycosyltransferase YjiC, YdhE family	406
643467184	402	23.26	27	399	31	393	1.0e-10	61.4	COG2814	Predicted arabinose efflux permease, MFS family	394
643467185	259	43.78	26	255	3	228	8.0e-46	177	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
643467188	309	35.01	3	298	17	353	8.0e-54	204	COG1858	Cytochrome c peroxidase	364
643467190	243	44.83	10	238	2	227	1.0e-49	190	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
643467191	449	24.43	1	434	2	406	3.0e-39	156	COG1819	UDP:flavonoid glycosyltransferase YjiC, YdhE family	406
643467196	428	36.25	4	409	1	408	3.0e-96	345	COG2081	Predicted flavoprotein YhiN	408
643467197	288	43.01	5	278	4	278	1.0e-79	289	COG0077	Prephenate dehydratase	279
643467198	182	53.28	55	174	13	134	8.0e-33	133	COG3474	Cytochrome c2	135
643467199	630	27.6	30	623	16	562	3.0e-72	266	COG4166	ABC-type oligopeptide transport system, periplasmic component	562
643467200	363	68.96	1	362	1	364	0.0e+00	556	COG4174	ABC-type microcin C transport system, permease component YejB	364
643467201	385	65.4	18	383	1	340	0.0e+00	498	COG4239	ABC-type microcin C transport system, permease component YejE	341
643467204	543	65.47	7	534	5	534	0.0e+00	777	COG4172	ABC-type microcin C transport system, duplicated ATPase component YejF	534
643467205	516	40.92	15	483	10	486	0.0e+00	478	COG0380	Trehalose-6-phosphate synthase	486
643467206	1085	27.93	678	1060	31	410	6.0e-35	143	COG3281	Predicted trehalose synthase	438
643467206	1085	35.06	13	516	1	505	2.0e-96	348	COG0366	Glycosidase	505
643467207	88	51.14	1	88	1	88	2.0e-13	67.2	COG0268	Ribosomal protein S20	88
643663617	314	52.3	12	314	3	304	3.0e-85	308	COG0181	Porphobilinogen deaminase	307
643663618	246	34.02	3	244	14	256	4.0e-33	134	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
643663620	168	16.55	7	145	11	152	5.0e-06	44.2	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
643663621	541	46.46	341	537	9	193	4.0e-34	139	COG2068	CTP:molybdopterin cytidylyltransferase MocA	199
643663622	561	32.73	58	548	1	442	1.0e-74	274	COG1793	ATP-dependent DNA ligase	444
643663623	105	38.27	13	93	11	91	2.0e-24	104	COG0759	Membrane-anchored protein YidD, putatitve component of membrane protein insertase Oxa1/YidC/SpoIIIJ	92
643663629	208	34.83	5	195	8	201	6.0e-28	117	COG1573	Uracil-DNA glycosylase	202
643663632	441	36.61	9	440	1	425	2.0e-87	316	COG0823	Periplasmic component of the Tol biopolymer transport system	425
643663638	130	37.59	1	130	1	131	3.0e-23	100	COG3607	Predicted lactoylglutathione lyase	133
643663644	308	30.9	4	301	2	297	5.0e-26	112	COG0583	DNA-binding transcriptional regulator, LysR family	297
643663645	71	45.07	1	71	1	69	2.0e-09	53.9	COG5639	Uncharacterized protein	77
643663646	346	36.43	88	343	8	254	8.0e-50	190	COG3504	Type IV secretory pathway, VirB9 components	265
643663647	435	24.19	1	276	1	261	2.0e-16	80.9	COG4584	Transposase	278
643663650	990	20.5	725	962	4	229	2.0e-10	61.5	COG2801	Transposase InsO and inactivated derivatives	232
643663653	414	53.69	9	411	1	404	0.0e+00	474	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
643663654	414	32.57	5	388	1	381	2.0e-47	183	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
643663655	203	30.89	28	203	16	206	5.0e-19	87.8	COG3316	Transposase (or an inactivated derivative)	215
643663658	395	22.07	86	371	24	284	2.0e-11	63.7	COG4974	Site-specific recombinase XerD	300
643663660	309	22.97	51	272	22	221	1.0e-08	53.8	COG2801	Transposase InsO and inactivated derivatives	232
643663662	579	30	13	249	1	222	1.0e-27	118	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
643663665	951	36.83	148	553	10	404	7.0e-53	202	COG3903	Predicted ATPase	414
643663668	722	36.98	180	714	77	620	6.0e-119	422	COG3914	Predicted O-linked N-acetylglucosamine transferase, SPINDLY family	620
643663669	831	41.59	1	829	35	844	0.0e+00	680	COG1643	HrpA-like RNA helicase	845
643663672	398	55.5	1	398	1	387	0.0e+00	515	COG0045	Succinyl-CoA synthetase, beta subunit	387
643663674	302	30.23	3	296	2	296	1.0e-26	113	COG0583	DNA-binding transcriptional regulator, LysR family	297
643663677	390	22.5	104	353	7	274	2.0e-06	47.1	COG4974	Site-specific recombinase XerD	300
643663679	342	35.21	1	335	1	325	5.0e-56	211	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
643663681	398	57.29	3	395	2	384	0.0e+00	540	COG0192	S-adenosylmethionine synthetase	388
643663682	607	23.89	43	595	18	559	6.0e-37	149	COG2936	Predicted acyl esterase	563
643663687	197	39.59	5	197	9	205	2.0e-44	172	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
643663690	882	39.39	366	628	77	328	1.0e-47	185	COG0642	Signal transduction histidine kinase	336
643663693	281	29.22	61	279	23	226	6.0e-13	68.1	COG2801	Transposase InsO and inactivated derivatives	232
643663697	124	35.24	20	124	4	108	5.0e-15	73.4	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
643663708	343	21.77	1	141	4	148	2.0e-14	73.8	COG2110	O-acetyl-ADP-ribose deacetylase (regulator of RNase III), contains Macro domain	179
643663709	433	24.19	1	276	1	261	8.0e-17	82	COG4584	Transposase	278
643663712	341	44.94	4	330	9	364	2.0e-88	319	COG1858	Cytochrome c peroxidase	364
