gene_oid	gene_length	percent_identity	query_start	query_end	subj_start	subj_end	evalue	bit_score	cog_id	cog_name	cog_length
2918277140	37	14.17	1	37	2	37	6.0e-09	30.3	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2918277141	400	98.91	10	377	3	364	3.2e-50	165.7	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918277142	259	98.51	1	257	4	267	7.5e-74	243.2	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918277143	312	99.33	4	307	2	297	5.8e-103	338.9	COG3246	Uncharacterized conserved protein, DUF849 family	298
2918277144	303	88.45	1	302	3	293	8.1e-86	282.7	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
2918277145	475	79.03	4	470	117	557	0.0e+00	472.5	COG3829	Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding Fis domains	560
2918277146	206	50.15	17	206	159	326	1.8e-20	68.5	COG0582	Integrase	309
2918277147	122	16.32	15	112	126	196	1.9e-09	31.1	COG3706	Two-component response regulator, PleD family, consists of two REC domains and a diguanylate cyclase (GGDEF) domain	435
2918277150	548	97.55	109	272	5	163	7.1e-40	131.1	COG3436	Transposase	157
2918277151	101	54.7	5	97	4	67	1.3e-18	62.1	COG2963	Transposase and inactivated derivatives	116
2918277153	88	49.38	2	88	28	107	6.5e-11	37	COG3666	Transposase	161
2918277155	300	93.35	1	300	6	300	2.9e-119	392.5	COG4227	Antirestriction protein ArdC	316
2918277159	281	97.06	2	276	3	299	2.8e-47	155.1	COG1336	CRISPR/Cas system CMR subunit Cmr4, Cas7 group, RAMP superfamily	298
2918277160	148	98.51	1	146	1	132	1.8e-10	35.4	COG3337	CRISPR/Cas system CMR-associated protein Cmr5, small subunit	134
2918277161	351	70.82	86	283	74	255	1.4e-31	104.3	COG1604	CRISPR/Cas system CMR subunit Cmr6, Cas7 group, RAMP superfamily	257
2918277163	152	8.21	40	147	721	787	4.1e-11	36.4	COG1112	Superfamily I DNA and/or RNA helicase	767
2918277165	638	21.48	457	611	449	584	4.9e-49	13	COG0296	1,4-alpha-glucan branching enzyme	628
2918277165	638	40.44	26	346	72	327	4.9e-49	146.2	COG0296	1,4-alpha-glucan branching enzyme	628
2918277167	84	54.62	7	83	5	75	4.1e-08	28.8	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918277168	884	24.64	264	430	285	404	1.3e-11	18.2	COG1061	Superfamily II DNA or RNA helicase	442
2918277168	884	25.46	18	232	61	184	1.3e-11	18.5	COG1061	Superfamily II DNA or RNA helicase	442
2918277173	53	58.73	2	51	12	48	2.3e-05	18.8	COG4877	Uncharacterized protein	63
2918277174	139	97.73	1	139	2	130	2.7e-28	93.4	COG1487	Predicted nucleic acid-binding protein, contains PIN domain	133
2918277175	81	67.5	1	74	1	54	1.1e-17	59	COG4691	Plasmid stability protein	80
2918277176	119	63.73	17	112	16	80	2.2e-13	44.4	COG4321	Predicted DNA-binding protein, contains Ribbon-helix-helix (RHH) domain	102
2918277177	234	79.9	6	162	31	185	3.3e-22	72.9	COG1525	Endonuclease YncB, thermonuclease family	192
2918277178	580	70.83	1	260	5	191	1.3e-26	89	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
2918277181	156	76.52	8	143	2	102	4.1e-21	70.2	COG0789	DNA-binding transcriptional regulator, MerR family	124
2918277182	110	96.81	5	98	2	92	2.5e-31	102.4	COG0776	Bacterial nucleoid DNA-binding protein	94
2918277183	323	99.08	2	323	3	325	0.0e+00	443.6	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
2918277184	350	98.23	4	340	2	334	5.8e-123	404.7	COG0416	Fatty acid/phospholipid biosynthesis enzyme	338
2918277185	61	98.25	1	57	1	56	2.7e-29	95.9	COG0333	Ribosomal protein L32	57
2918277186	191	85.47	17	190	26	178	9.7e-09	26.2	COG1399	Uncharacterized metal-binding protein YceD, DUF177 family	176
2918277187	183	96.67	1	180	4	177	9.1e-45	147.5	COG5452	Uncharacterized protein	180
2918277188	155	98	1	142	4	150	2.2e-30	100.3	COG2913	Outer membrane protein assembly factor BamE, lipoprotein component of the BamABCDE complex	147
2918277189	700	99.15	1	700	5	701	0.0e+00	991.8	COG3808	Na+ or H+-translocating membrane pyrophosphatase	703
2918277190	152	60.38	1	147	20	115	4.8e-07	24.1	COG1580	Flagellar basal body-associated protein FliL	159
2918277191	334	99.38	8	334	3	320	1.1e-84	278.7	COG0611	Thiamine monophosphate kinase	317
2918277192	184	94.77	13	171	7	151	2.8e-32	106.3	COG0781	Transcription termination factor NusB	151
2918277193	154	93.42	1	148	11	152	5.4e-46	150.8	COG0054	6,7-dimethyl-8-ribityllumazine synthase (Riboflavin synthase beta chain)	152
2918277194	375	87.24	210	374	3	173	1.1e-32	106.9	COG0807	GTP cyclohydrolase II	193
2918277194	375	97.54	8	210	5	202	1.9e-85	279.5	COG0108	3,4-dihydroxy-2-butanone 4-phosphate synthase	203
2918277195	195	94.63	1	195	1	194	1.1e-73	241.3	COG0307	Riboflavin synthase alpha chain	204
2918277196	378	95.89	12	156	5	144	5.9e-58	188.8	COG0117	Pyrimidine deaminase domain of riboflavin biosynthesis protein RibD	146
2918277196	378	98.64	157	378	2	218	6.1e-66	216	COG1985	Pyrimidine reductase, riboflavin biosynthesis	218
2918277197	154	96.79	1	154	1	151	2.4e-67	220.4	COG1327	Transcriptional regulator NrdR, contains Zn-ribbon and ATP-cone domains	156
2918277198	436	98.8	14	434	5	414	0.0e+00	643	COG0112	Glycine/serine hydroxymethyltransferase	413
2918277199	145	92.72	4	145	3	142	6.8e-55	179.6	COG0698	Ribose 5-phosphate isomerase RpiB	151
2918277200	147	90.54	3	146	10	143	1.4e-61	201.3	COG4957	Predicted transcriptional regulator	148
2918277203	170	98.2	1	167	1	164	5.8e-61	199.9	COG3685	Ferritin-like metal-binding protein YciE	167
2918277206	160	48.79	11	158	3	143	2.1e-15	51.2	COG5483	Uncharacterized conserved protein, DUF488 family	289
2918277207	149	94.84	1	149	4	150	5.3e-47	154.2	COG2153	Predicted N-acyltransferase, GNAT family	155
2918277208	524	97.76	58	522	10	490	2.5e-110	364	COG1793	ATP-dependent DNA ligase	444
2918277209	320	85.13	2	317	51	422	1.6e-52	172.3	COG1236	RNA processing exonuclease, beta-lactamase fold, Cft2 family	427
2918277210	309	95.16	2	305	14	308	0.0e+00	442.7	COG2313	Pseudouridine-5'-phosphate glycosidase (pseudoU degradation)	310
2918277213	294	94.3	1	251	14	261	2.5e-85	280.9	COG0005	Purine nucleoside phosphorylase	262
2918277214	230	85.96	2	211	17	212	5.3e-39	128.8	COG0705	Membrane associated serine protease, rhomboid family	228
2918277215	260	97.36	1	257	8	265	7.2e-64	210.3	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918277216	622	82.98	3	364	40	390	5.7e-52	171.7	COG2730	Aryl-phospho-beta-D-glucosidase BglC, GH1 family	407
2918277218	813	97.8	1	808	7	852	0.0e+00	786.7	COG1201	Lhr-like helicase	814
2918277219	226	87.45	9	224	9	217	6.0e-49	160.9	COG1407	Metallophosphoesterase superfamily enzyme	235
2918277220	162	69.76	4	162	57	199	1.3e-57	189.8	COG2335	Uncaracterized surface protein containing fasciclin (FAS1) repeats	187
2918277221	468	96.76	1	464	14	461	0.0e+00	506.3	COG0415	Deoxyribodipyrimidine photolyase	461
2918277222	671	99.36	21	671	4	622	0.0e+00	765.8	COG3211	Secreted phosphatase, PhoX family	616
2918277223	160	95.17	11	160	5	142	2.8e-38	125.3	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
2918277224	380	97.24	11	376	1	317	3.6e-92	299	COG0523	GTPase, G3E family	323
2918277226	327	74.12	15	305	5	236	5.7e-34	112.2	COG1216	Glycosyltransferase, GT2 family	305
2918277227	409	98.82	1	403	4	422	5.7e-62	204.3	COG1055	Na+/H+ antiporter NhaD or related arsenite permease	424
2918277228	145	79.63	1	130	27	155	4.4e-14	47.6	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2918277229	274	97.07	1	272	4	268	4.9e-47	155	COG1235	Phosphoribosyl 1,2-cyclic phosphodiesterase	269
2918277231	390	27.59	2	128	102	141	1.3e-03	2.9	COG1730	Prefoldin subunit 5	145
2918277231	390	33.79	137	198	88	136	1.3e-03	8.8	COG1730	Prefoldin subunit 5	145
2918277233	307	96.07	1	300	2	294	3.6e-87	287	COG0053	Divalent metal cation (Fe/Co/Zn/Cd) transporter	304
2918277234	202	89.25	1	202	24	214	1.1e-87	287.6	COG0259	Pyridoxine/pyridoxamine 5'-phosphate oxidase	214
2918277235	155	95.59	10	153	5	134	9.5e-26	84.9	COG4520	Surface antigen	136
2918277236	319	37.14	165	317	219	361	3.1e-78	122.6	COG0484	DnaJ-class molecular chaperone with C-terminal Zn finger domain	371
2918277236	319	37.66	2	173	3	147	3.1e-78	137	COG0484	DnaJ-class molecular chaperone with C-terminal Zn finger domain	371
2918277237	596	96.01	8	591	19	595	0.0e+00	656.2	COG0465	ATP-dependent Zn proteases	596
2918277238	247	98.71	4	244	2	230	7.4e-55	180.3	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918277239	606	48.82	39	198	2	104	5.2e-06	20.3	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918277239	606	70.05	231	599	115	390	6.1e-60	198.6	COG0642	Signal transduction histidine kinase	336
2918277241	312	69.66	4	312	131	433	6.0e-79	260.2	COG3706	Two-component response regulator, PleD family, consists of two REC domains and a diguanylate cyclase (GGDEF) domain	435
2918277244	105	98.11	1	105	2	105	3.1e-38	125.2	COG2076	Multidrug transporter EmrE and related cation transporters	106
2918277245	345	95.47	10	274	6	258	7.3e-46	150.8	COG0300	Short-chain dehydrogenase	265
2918277246	139	98.54	1	137	2	136	1.0e-47	156.1	COG1765	Uncharacterized OsmC-related protein	137
2918277249	430	99.52	1	428	1	419	0.0e+00	600.6	COG0766	UDP-N-acetylglucosamine enolpyruvyl transferase	421
2918277250	184	97.84	2	184	2	182	4.0e-63	207.1	COG0717	Deoxycytidine triphosphate deaminase	183
2918277251	147	60.49	5	134	58	155	4.5e-10	34.8	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2918277252	306	97.67	6	301	4	297	6.5e-35	115.4	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918277254	657	97.99	1	649	1	537	0.0e+00	505.6	COG0367	Asparagine synthetase B (glutamine-hydrolyzing)	542
2918277256	327	99.07	1	326	2	319	1.3e-89	295.6	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2918277257	393	91.44	12	381	33	406	1.3e-32	108.4	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918277258	329	96.63	1	306	8	322	1.0e-52	173.8	COG0472	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase	319
2918277259	317	98.44	1	317	2	317	1.9e-58	193.2	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2918277260	643	98.67	10	637	2	594	0.0e+00	625	COG1086	NDP-sugar epimerase, includes UDP-GlcNAc-inverting 4,6-dehydratase FlaA1 and capsular polysaccharide biosynthesis protein EpsC	588
2918277262	647	99.17	9	605	2	597	0.0e+00	885.8	COG0465	ATP-dependent Zn proteases	596
2918277263	431	61.69	3	249	22	211	5.6e-52	171	COG0037	tRNA(Ile)-lysidine synthase TilS/MesJ	298
2918277264	304	81.82	4	299	47	262	3.7e-47	155.8	COG1729	Periplasmic TolA-binding protein (function unknown)	262
2918277265	157	61.31	8	157	74	195	1.4e-42	140.8	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
2918277266	450	96.74	18	449	14	428	2.8e-130	429.7	COG0823	Periplasmic component of the Tol biopolymer transport system	425
2918277267	368	67.88	125	341	57	242	9.0e-02	10	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
2918277268	165	93.53	9	146	7	136	1.1e-42	139.9	COG0848	Biopolymer transport protein ExbD	137
2918277269	241	99.07	24	238	2	215	3.8e-67	221.1	COG0811	Biopolymer transport protein ExbB/TolQ	216
2918277270	151	96.4	11	147	3	136	1.2e-43	143.1	COG0824	Acyl-CoA thioesterase FadM	137
2918277271	366	96.08	8	338	12	330	0.0e+00	495.5	COG2255	Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit	332
2918277272	210	99.5	1	209	1	200	2.2e-56	185.1	COG0632	Holliday junction resolvasome RuvABC DNA-binding subunit	201
2918277273	355	86.82	205	327	13	124	2.1e-42	137.8	COG2852	Very-short-patch-repair endonuclease	129
2918277273	355	95.03	19	177	1	153	5.8e-60	195.9	COG0817	Holliday junction resolvasome RuvABC endonuclease subunit	160
2918277274	250	99.59	1	243	1	242	1.4e-94	310.8	COG0217	Transcriptional and/or translational regulatory protein YebC/TACO1	241
2918277275	273	99.25	1	270	1	264	1.2e-101	334.1	COG1692	Calcineurin-like phosphoesterase	266
2918277276	193	96.86	4	192	4	188	1.4e-42	140.6	COG0212	5-formyltetrahydrofolate cyclo-ligase	191
2918277278	104	71.43	1	104	1	75	3.4e-13	44.2	COG3027	Cell division protein ZapA, inhibits GTPase activity of FtsZ	105
2918277279	74	12.47	1	72	141	196	3.0e-03	11.1	COG3014	Uncharacterized protein	449
2918277280	667	98.64	11	667	7	660	0.0e+00	931.3	COG0021	Transketolase	663
2918277281	335	98.81	2	335	2	332	0.0e+00	480.5	COG0057	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase	335
2918277282	336	96.33	1	334	11	404	7.5e-33	109.1	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918277283	114	94.59	1	109	3	107	8.3e-31	101.2	COG4226	Predicted nuclease of the RNAse H fold, HicB family	111
2918277284	139	28.82	5	103	25	107	1.5e-03	12.4	COG0191	Fructose/tagatose bisphosphate aldolase	286
2918277286	309	95.91	14	309	5	262	1.7e-59	195.9	COG1830	Fructose-bisphosphate aldolase class Ia, DhnA family	265
2918277287	211	97.16	1	210	4	208	1.2e-63	208.7	COG0352	Thiamine monophosphate synthase	211
2918277288	268	96.14	4	254	5	253	7.6e-53	173.8	COG0730	Uncharacterized membrane protein YfcA	258
2918277289	336	77.04	1	313	12	266	3.0e-19	60.7	COG0530	Ca2+/Na+ antiporter	320
2918277290	453	98.2	9	453	9	444	1.1e-102	338.5	COG2067	Long-chain fatty acid transport protein	440
2918277291	335	97.58	5	333	9	331	3.6e-64	211.9	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2918277292	349	97.83	2	349	6	320	3.4e-111	366.1	COG2269	Elongation factor P--beta-lysine ligase (EF-P beta-lysylation pathway)	322
2918277293	188	98.47	1	130	3	131	1.2e-42	139.2	COG0231	Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)	131
2918277294	277	97.68	4	261	4	256	3.1e-85	280.2	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
2918277295	265	62.81	101	250	48	172	9.7e-10	33.1	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
2918277297	439	81.85	3	439	46	266	1.6e-36	114.7	COG1360	Flagellar motor protein MotB	244
2918277298	525	97.79	34	525	5	490	0.0e+00	609.8	COG1003	Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain	496
2918277299	447	97.12	1	447	11	448	0.0e+00	493.7	COG0403	Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain	450
2918277300	124	92.37	1	122	9	129	4.9e-49	159.9	COG0509	Glycine cleavage system H protein (lipoate-binding)	131
2918277301	374	98.96	8	374	2	382	1.3e-115	380.9	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
2918277304	325	97.63	5	299	3	290	9.0e-119	390.4	COG0761	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH	294
2918277305	327	96.42	1	320	5	327	2.5e-92	303.8	COG2334	Ser/Thr protein kinase RdoA involved in Cpx stress response, MazF antagonist	331
2918277306	157	96.79	8	157	2	152	1.6e-61	201.5	COG0328	Ribonuclease HI	154
2918277307	527	98.24	1	526	5	562	1.8e-94	311.6	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2918277308	265	93.48	1	260	2	259	1.5e-80	265.4	COG2162	Arylamine N-acetyltransferase	275
2918277309	160	100	1	160	1	166	3.6e-63	206.6	COG0678	Peroxiredoxin	165
2918277310	698	71.85	221	686	172	610	4.1e-101	334.1	COG4232	Thiol:disulfide interchange protein	569
2918277311	191	96.39	3	191	8	194	4.4e-67	219.8	COG1678	Putative transcriptional regulator, AlgH/UPF0301 family	194
2918277313	196	91.44	5	196	15	185	2.2e-46	152.9	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
2918277314	418	95.88	1	412	17	435	1.1e-106	351.8	COG0612	Predicted Zn-dependent peptidase	438
2918277315	469	99.28	1	461	2	417	0.0e+00	435	COG0498	Threonine synthase	411
2918277316	440	84.16	3	370	40	395	3.4e-48	159.4	COG2730	Aryl-phospho-beta-D-glucosidase BglC, GH1 family	407
2918277317	501	99.4	2	500	3	496	0.0e+00	561	COG2317	Zn-dependent carboxypeptidase, M32 family	497
2918277318	246	94.09	3	245	5	243	6.7e-74	242.8	COG3346	Cytochrome oxidase assembly protein ShyY1	252
2918277319	125	91.27	2	121	10	124	2.0e-45	148.2	COG5349	Uncharacterized conserved protein, DUF983 family	126
2918277320	290	97.18	69	284	6	212	1.8e-67	221.2	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
2918277321	202	92.12	1	193	12	198	8.4e-76	248.5	COG3175	Cytochrome c oxidase assembly protein Cox11	195
2918277323	297	92.18	4	297	19	301	9.9e-117	384.3	COG0109	Polyprenyltransferase (heme O synthase)	304
2918277324	535	90.16	17	535	7	519	0.0e+00	777	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
2918277325	279	85.83	6	278	17	234	1.7e-72	238.1	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
2918277326	447	95.75	14	446	12	417	1.3e-120	397.5	COG4949	Uncharacterized membrane-anchored protein	424
2918277327	477	96.71	21	475	15	455	0.0e+00	490.4	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
2918277328	174	78.89	91	174	6	76	2.7e-16	26.1	COG3830	ACT domain, binds amino acids and other small ligands	90
2918277328	174	87.78	2	85	4	82	2.7e-16	26.7	COG3830	ACT domain, binds amino acids and other small ligands	90
2918277331	54	98.15	1	54	1	53	7.1e-25	81.7	COG5487	Uncharacterized membrane protein YtjA, UPF0391 family	54
2918277332	206	88.17	38	202	17	180	1.7e-49	162.2	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918277333	297	90.43	3	269	11	284	5.4e-36	119.1	COG0741	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)	296
2918277335	345	99.13	2	343	2	341	1.9e-110	363.6	COG2008	Threonine aldolase	342
2918277337	334	98.97	12	322	3	291	4.5e-96	316.2	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
2918277338	294	80.65	1	293	60	334	2.9e-93	307.7	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
2918277341	430	99.77	1	429	1	429	0.0e+00	611.1	COG0104	Adenylosuccinate synthase	430
2918277342	387	89.51	7	371	4	353	5.1e-68	224	COG3705	ATP phosphoribosyltransferase regulatory subunit HisZ	390
2918277344	486	97.67	5	486	2	503	5.3e-104	343.3	COG0168	Trk-type K+ transport system, membrane component	499
2918277345	386	98.92	4	380	3	368	1.4e-108	357.6	COG1932	Phosphoserine aminotransferase	365
2918277346	378	6.26	8	176	295	343	1.7e-04	4.6	COG4409	Neuraminidase (sialidase)	728
2918277346	378	11.75	190	291	568	659	1.7e-04	7.4	COG4409	Neuraminidase (sialidase)	728
2918277347	333	17.32	209	314	264	325	1.6e-20	13.9	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
2918277347	333	39.94	22	182	19	161	1.6e-20	52.1	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
2918277348	149	91.19	1	148	13	157	6.5e-37	120.9	COG2030	Acyl dehydratase	159
2918277349	156	44.97	8	146	80	164	8.4e-13	43.3	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
2918277350	263	99.32	1	263	2	291	8.5e-68	223.7	COG0384	Predicted epimerase YddE/YHI9, PhzF superfamily	291
2918277351	137	64.81	5	136	44	148	2.2e-07	26.3	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2918277352	82	57.14	4	81	27	62	1.1e-16	54.9	COG5457	Uncharacterized conserved protein YjiS, DUF1127 family	63
2918277353	242	92.67	3	242	16	230	3.3e-74	243.8	COG0670	Integral membrane protein, interacts with FtsH	233
2918277354	169	77.7	3	134	24	138	3.7e-05	17.4	COG4103	Uncharacterized conserved protein, tellurite resistance protein B (TerB) family	148
2918277355	327	96.88	51	316	2	249	1.1e-69	229.3	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
2918277357	104	23.5	12	85	10	60	4.6e-04	14.3	COG5637	Uncharacterized membrane protein	217
2918277358	469	98.46	11	462	3	451	8.6e-94	309.4	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
2918277359	266	97.72	1	263	5	261	4.7e-97	318.9	COG0351	Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase	263
2918277360	456	97.49	1	451	11	476	0.0e+00	440.5	COG1109	Phosphomannomutase	464
2918277361	375	94.6	107	373	4	266	5.9e-92	302.2	COG0294	Dihydropteroate synthase	274
2918277363	150	51.85	32	142	59	156	1.2e-04	16.7	COG3945	Hemerythrin-like domain	189
2918277364	320	93.19	4	317	19	319	1.3e-99	327.7	COG4301	Uncharacterized conserved protein, contains predicted SAM-dependent methyltransferase domain	321
2918277365	426	98.8	93	426	3	331	1.7e-58	187.1	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
2918277366	388	94.72	5	268	3	253	8.1e-53	173.7	COG0300	Short-chain dehydrogenase	265
2918277367	924	64.86	415	924	216	645	1.7e-124	410.7	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2918277367	924	93.75	14	350	20	349	7.7e-33	108.1	COG3614	Extracellular (periplasmic) sensor domain CHASE1 (specificity unknown)	348
2918277369	524	98.86	3	461	2	433	1.0e-106	351.5	COG1236	RNA processing exonuclease, beta-lactamase fold, Cft2 family	427
2918277370	296	91.82	3	295	11	302	4.4e-41	135.5	COG0462	Phosphoribosylpyrophosphate synthetase	314
2918277373	80	97.26	1	73	1	71	8.9e-31	100.4	COG3655	DNA-binding transcriptional regulator, XRE family	73
2918277374	295	92.03	2	294	2	278	7.8e-57	187.9	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918277375	409	50.91	225	408	10	204	3.3e-19	26.8	COG0477	MFS family permease	338
2918277375	409	71.8	22	275	5	279	3.3e-19	38.9	COG0477	MFS family permease	338
2918277376	293	68.97	1	293	134	433	3.2e-93	307.3	COG3706	Two-component response regulator, PleD family, consists of two REC domains and a diguanylate cyclase (GGDEF) domain	435
2918277380	329	91.16	11	329	30	328	4.7e-78	256.8	COG0598	Mg2+ and Co2+ transporter CorA	322
2918277382	363	97.45	2	344	6	349	7.6e-92	302.3	COG1744	Basic membrane lipoprotein Med, periplasmic binding protein (PBP1-ABC) superfamily	345
2918277383	310	97.7	2	310	5	301	2.3e-103	339.9	COG1079	ABC-type uncharacterized transport system, permease component	304
2918277384	363	96.93	4	360	5	351	1.0e-112	370.9	COG4603	ABC-type uncharacterized transport system, permease component	356
2918277385	521	99.4	10	505	4	501	0.0e+00	625.2	COG3845	ABC-type uncharacterized transport system, ATPase component	501
2918277386	132	67.11	24	130	49	150	7.7e-18	59.5	COG0782	Transcription elongation factor, GreA/GreB family	151
2918277387	301	92.86	1	301	13	298	1.3e-59	196.9	COG0354	Folate-binding Fe-S cluster repair protein YgfZ, possible role in tRNA modification	305
2918277388	191	73.86	56	119	3	67	1.9e-09	31.6	COG1873	Sporulation protein YlmC, PRC-barrel domain family	87
2918277389	231	87.5	1	231	33	263	1.4e-67	222.3	COG5387	Chaperone required for the assembly of the mitochondrial F1-ATPase	264
2918277390	243	95.05	3	220	5	215	5.0e-50	165	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
2918277391	601	82.61	3	313	55	358	3.4e-18	55.3	COG0457	Tetratricopeptide (TPR) repeat	291
2918277392	340	98.63	9	316	4	291	1.7e-75	248.7	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
2918277393	133	96.03	4	129	4	124	3.7e-34	112.1	COG0239	Fluoride ion exporter CrcB/FEX, affects chromosome condensation	126
2918277394	191	84.95	5	181	3	177	1.2e-32	107.9	COG1335	Nicotinamidase-related amidase	205
2918277397	440	96.8	11	436	13	435	0.0e+00	582.6	COG2256	Replication-associated recombination protein RarA (DNA-dependent ATPase)	436
2918277399	87	15.68	6	78	230	290	5.6e-05	16.8	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
2918277400	192	97.52	1	164	1	157	1.0e-41	136.9	COG1238	Uncharacterized membrane protein YqaA, SNARE-associated domain	161
2918277401	139	100	1	116	1	116	5.5e-52	169.5	COG0203	Ribosomal protein L17	116
2918277402	339	99.37	10	330	3	319	1.4e-121	400	COG0202	DNA-directed RNA polymerase, alpha subunit/40 kD subunit	317
2918277403	132	96.92	1	132	5	130	2.5e-61	200.4	COG0100	Ribosomal protein S11	129
2918277404	122	100	1	122	1	121	1.2e-52	171.9	COG0099	Ribosomal protein S13	121
2918277406	480	99.16	8	477	3	476	0.0e+00	592.4	COG0469	Pyruvate kinase	477
2918277407	179	33.42	6	176	94	216	6.0e-11	37.7	COG0457	Tetratricopeptide (TPR) repeat	291
2918277408	715	98.9	1	714	4	724	0.0e+00	842.9	COG0480	Translation elongation factor EF-G, a GTPase	697
2918277409	115	92.65	1	115	9	134	6.8e-33	108.2	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
2918277410	256	80.16	4	247	37	242	1.1e-11	37.2	COG3591	V8-like Glu-specific endopeptidase	251
2918277411	735	96.35	2	609	2	555	1.4e-121	401.3	COG0550	DNA topoisomerase IA	570
2918277412	683	94.2	2	683	46	808	1.7e-127	420.4	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
2918277413	355	98.26	1	355	3	341	8.4e-87	286.3	COG2070	NAD(P)H-dependent flavin oxidoreductase YrpB, nitropropane dioxygenase family	336
2918277414	342	92.9	134	339	11	180	9.2e-56	182.6	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2918277415	166	50.6	5	156	70	196	9.2e-31	101.4	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2918277416	164	92.09	5	141	9	136	2.0e-31	103.4	COG0824	Acyl-CoA thioesterase FadM	137
2918277417	1163	97.12	1	305	8	310	2.2e-97	320.1	COG0646	Methionine synthase I (cobalamin-dependent), methyltransferase domain	311
2918277417	1163	99.65	315	1163	4	857	0.0e+00	977.5	COG1410	Methionine synthase I, cobalamin-binding domain	842
2918277418	293	95.56	1	287	12	291	2.7e-104	343	COG0685	5,10-methylenetetrahydrofolate reductase	291
2918277419	327	48.54	105	278	53	168	7.5e-26	85.1	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
2918277420	258	89.64	7	256	9	233	2.4e-69	227.7	COG2853	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, lipoprotein component MlaA	250
2918277421	205	96.04	1	201	7	200	1.8e-46	153.1	COG2854	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic MlaC component	202
2918277422	493	27.89	130	205	115	184	8.6e-64	52.8	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2918277422	493	37.45	21	126	102	195	8.6e-64	80.3	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2918277422	493	56.57	224	381	73	214	8.6e-64	86.1	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2918277423	558	99.44	5	539	3	534	0.0e+00	601.5	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
2918277424	155	97.33	1	150	2	147	7.9e-53	173	COG1671	Uncharacterized conserved protein YaiI, UPF0178 family	150
2918277425	444	53.15	237	441	56	190	1.4e-11	39.1	COG0847	DNA polymerase III, epsilon subunit or related 3'-5' exonuclease	243
2918277427	325	94.08	11	323	15	316	1.0e-48	160.6	COG2064	Pilus assembly protein TadC	320
2918277428	331	98.71	7	330	4	308	1.9e-75	248	COG4965	Flp pilus assembly protein TadB	309
2918277429	644	96.96	249	609	8	358	0.0e+00	499.4	COG4962	Pilus assembly protein, ATPase of CpaF family	355
2918277430	407	73.66	71	407	92	379	2.7e-46	152.6	COG4963	Flp pilus assembly protein, ATPase CpaE	366
2918277432	483	88.93	11	471	30	463	4.0e-116	382.6	COG4964	Flp pilus assembly protein, secretin CpaC	455
2918277433	333	89.86	1	275	1	248	5.6e-58	190.6	COG3745	Flp pilus assembly protein CpaB	276
2918277434	162	91.67	1	158	6	159	1.5e-30	100.6	COG4960	Flp pilus assembly protein, protease CpaA	168
2918277435	68	93.1	1	62	3	56	1.5e-14	48.2	COG3847	Flp pilus assembly protein, pilin Flp	58
2918277437	579	63.5	72	578	218	638	1.0e-67	223.2	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2918277439	158	98.09	1	157	1	154	7.7e-69	225.2	COG2193	Bacterioferritin (cytochrome b1)	157
2918277440	728	97.73	172	728	9	525	0.0e+00	502.1	COG1640	4-alpha-glucanotransferase	520
2918277441	340	52.16	10	200	4	124	1.2e-13	43.4	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918277442	717	97.87	1	709	7	695	0.0e+00	927.1	COG1523	Pullulanase/glycogen debranching enzyme	697
2918277443	748	12.32	23	114	17	94	0.0e+00	10.5	COG0296	1,4-alpha-glucan branching enzyme	628
2918277443	748	99.68	115	746	2	632	0.0e+00	896.2	COG0296	1,4-alpha-glucan branching enzyme	628
2918277444	1099	88.89	652	1099	46	453	4.7e-103	339.7	COG3281	Predicted trehalose synthase	438
2918277444	1099	99.81	13	524	1	516	5.3e-123	406.5	COG0366	Glycosidase	505
2918277448	1115	14.12	962	1076	436	508	9.6e-51	4.1	COG0366	Glycosidase	505
2918277448	1115	41.01	6	283	35	246	9.6e-51	78.3	COG0366	Glycosidase	505
2918277448	1115	53.97	650	934	30	308	9.6e-51	89.6	COG0366	Glycosidase	505
2918277449	277	85.19	2	245	38	267	1.3e-94	311.1	COG2326	Polyphosphate kinase 2, PPK2 family	270
2918277450	598	94.38	10	451	20	439	9.5e-79	259.6	COG0038	H+/Cl- antiporter ClcA	443
2918277452	240	99.16	8	240	2	236	1.7e-84	277.3	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2918277453	586	95.98	17	324	10	319	2.4e-65	215.2	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918277453	586	98.82	341	583	4	254	2.1e-72	237.4	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2918277454	290	98.34	1	289	4	299	1.3e-66	219.8	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2918277455	373	89.89	14	351	13	341	3.2e-44	146	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918277457	104	69.23	1	90	17	97	1.5e-16	54.8	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
2918277458	693	62.35	46	417	143	407	7.4e-47	154.6	COG0840	Methyl-accepting chemotaxis protein	408
2918277459	297	96.35	11	297	8	297	5.0e-46	151.9	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918277460	315	95.68	27	310	7	294	7.7e-41	134.8	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918277461	718	96.58	222	702	4	483	1.4e-71	235.7	COG1233	Phytoene dehydrogenase-related protein	487
2918277462	299	97.34	4	293	5	297	8.3e-41	134.7	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918277463	440	99.31	1	439	3	435	0.0e+00	531.9	COG0213	Thymidine phosphorylase	435
2918277464	272	94.74	18	264	6	221	5.9e-66	216.6	COG0274	Deoxyribose-phosphate aldolase	228
2918277465	277	97.34	3	269	5	260	4.1e-78	257.2	COG0005	Purine nucleoside phosphorylase	262
2918277466	136	93.43	1	136	9	136	2.5e-42	138.9	COG0295	Cytidine deaminase	134
2918277467	324	98.03	1	324	6	303	2.8e-105	346.2	COG1079	ABC-type uncharacterized transport system, permease component	304
2918277468	375	95.53	9	372	11	352	4.6e-113	371.9	COG4603	ABC-type uncharacterized transport system, permease component	356
2918277469	509	99.4	6	507	4	501	0.0e+00	640.1	COG3845	ABC-type uncharacterized transport system, ATPase component	501
2918277470	327	94.05	1	327	14	345	2.4e-102	337.2	COG1744	Basic membrane lipoprotein Med, periplasmic binding protein (PBP1-ABC) superfamily	345
2918277471	217	96.15	2	207	5	204	2.4e-25	83.4	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
2918277472	221	97.12	5	208	5	206	1.4e-42	139.9	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
2918277473	156	90.8	1	154	16	173	2.2e-07	22.7	COG5430	Spore coat protein U (SCPU) domain, function unknown	174
2918277474	613	99.32	28	603	3	590	0.0e+00	570.6	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
2918277475	73	93.33	1	73	1	70	2.4e-26	86.5	COG0254	Ribosomal protein L31	75
2918277476	138	71.43	2	137	23	147	3.5e-28	92.8	COG5317	Uncharacterized protein	175
2918277477	152	94.52	1	139	9	146	6.5e-38	124.5	COG0071	Molecular chaperone IbpA, HSP20 family	146
2918277478	630	74.62	242	628	95	388	5.3e-76	251.3	COG0642	Signal transduction histidine kinase	336
2918277479	264	97.29	1	264	5	291	5.3e-46	152.2	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918277480	436	98.83	2	433	5	426	0.0e+00	630.1	COG2873	O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent	426
2918277481	564	91.29	39	559	36	423	3.8e-62	201.3	COG0840	Methyl-accepting chemotaxis protein	408
2918277482	380	93.77	3	372	2	347	3.9e-95	313.6	COG2170	Gamma-glutamyl:cysteine ligase YbdK, ATP-grasp superfamily	369
2918277483	296	91.25	35	293	10	249	6.7e-94	308.9	COG3931	Predicted N-formylglutamate amidohydrolase	263
2918277484	316	96.35	25	316	7	296	1.9e-44	146.8	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918277485	253	96.27	9	243	6	237	6.6e-60	197	COG2186	DNA-binding transcriptional regulator, FadR family	241
2918277486	215	99.46	1	214	1	184	5.5e-69	226.7	COG0563	Adenylate kinase or related kinase	178
2918277487	446	97.05	7	441	10	436	0.0e+00	515.4	COG0201	Preprotein translocase subunit SecY	436
2918277488	161	98.05	2	154	2	152	3.5e-42	138.8	COG0200	Ribosomal protein L15	152
2918277489	63	94.55	7	61	3	54	2.6e-25	82.6	COG1841	Ribosomal protein L30/L7E	55
2918277490	190	94.02	1	180	11	183	3.5e-70	229.7	COG0098	Ribosomal protein S5	181
2918277491	120	93.65	1	120	9	126	3.8e-45	148.1	COG0256	Ribosomal protein L18	125
2918277492	177	98.88	1	177	1	177	2.1e-67	220.9	COG0097	Ribosomal protein L6P/L9E	178
2918277493	130	97.74	1	130	4	133	1.2e-49	162.2	COG0096	Ribosomal protein S8	132
2918277494	101	96.72	41	101	3	61	2.4e-26	86.4	COG0199	Ribosomal protein S14	61
2918277495	180	98.33	2	180	2	178	3.2e-82	269.2	COG0094	Ribosomal protein L5	180
2918277496	105	98.15	1	104	2	107	1.0e-32	107.3	COG0198	Ribosomal protein L24	104
2918277497	122	100	1	122	1	123	4.2e-59	192.6	COG0093	Ribosomal protein L14	122
2918277498	84	83.91	1	80	7	79	5.4e-37	120.3	COG0186	Ribosomal protein S17	87
2918277499	68	98.53	1	66	1	67	2.8e-27	89.3	COG0255	Ribosomal protein L29	69
2918277500	142	93.29	1	142	2	140	6.6e-59	192.6	COG0197	Ribosomal protein L16/L10AE	146
2918277501	256	97.42	12	249	1	227	3.9e-97	318.7	COG0092	Ribosomal protein S3	233
2918277502	130	93.96	5	125	8	147	1.2e-34	113.6	COG0091	Ribosomal protein L22	120
2918277503	92	98.92	1	92	1	92	4.1e-40	130.3	COG0185	Ribosomal protein S19	93
2918277504	276	99.64	1	275	1	274	1.1e-125	413.1	COG0090	Ribosomal protein L2	275
2918277505	92	97.87	1	92	1	92	3.2e-35	115.3	COG0089	Ribosomal protein L23	94
2918277506	206	97.7	1	206	2	213	3.1e-65	214.2	COG0088	Ribosomal protein L4	214
2918277507	236	97.8	2	215	2	223	2.0e-77	254.5	COG0087	Ribosomal protein L3	218
2918277508	102	98.08	1	102	1	102	1.1e-48	158.4	COG0051	Ribosomal protein S10	104
2918277509	396	99.75	1	396	1	393	0.0e+00	739.4	COG0050	Translation elongation factor EF-Tu, a GTPase	394
2918277510	692	98.08	1	692	8	722	0.0e+00	950.1	COG0480	Translation elongation factor EF-G, a GTPase	697
2918277511	156	99.32	2	149	2	148	7.7e-64	208.4	COG0049	Ribosomal protein S7	148
2918277512	123	95.35	1	123	7	129	2.9e-64	209.1	COG0048	Ribosomal protein S12	129
2918277513	1390	5.06	874	935	407	447	0.0e+00	12.4	COG0086	DNA-directed RNA polymerase, beta' subunit/160 kD subunit	808
2918277513	1390	18.99	1044	1363	594	747	0.0e+00	25.3	COG0086	DNA-directed RNA polymerase, beta' subunit/160 kD subunit	808
2918277513	1390	99.38	14	843	4	809	0.0e+00	1007.1	COG0086	DNA-directed RNA polymerase, beta' subunit/160 kD subunit	808
2918277514	1374	97.33	1	1373	26	1082	0.0e+00	1498.7	COG0085	DNA-directed RNA polymerase, beta subunit/140 kD subunit	1060
2918277515	125	98.4	1	125	3	125	6.0e-51	166.8	COG0222	Ribosomal protein L7/L12	124
2918277516	172	96.59	2	171	5	174	1.4e-51	169.1	COG0244	Ribosomal protein L10	175
2918277517	234	99.57	1	228	1	229	3.9e-95	312.4	COG0081	Ribosomal protein L1	228
2918277518	143	99.29	2	143	1	140	3.2e-63	206.6	COG0080	Ribosomal protein L11	141
2918277519	176	99.45	1	176	1	182	1.3e-69	228.4	COG0250	Transcription antitermination factor NusG	178
2918277520	62	72.6	1	56	19	71	7.0e-20	65.2	COG0690	Preprotein translocase subunit SecE	73
2918277522	396	99.75	1	396	1	393	0.0e+00	739.4	COG0050	Translation elongation factor EF-Tu, a GTPase	394
2918277525	288	92.02	17	288	17	258	4.8e-68	223.9	COG0566	tRNA G18 (ribose-2'-O)-methylase SpoU	260
2918277526	644	99.24	4	571	5	528	0.0e+00	530.3	COG0737	2',3'-cyclic-nucleotide 2'-phosphodiesterase/5'- or 3'-nucleotidase, 5'-nucleotidase family	517
2918277529	190	69.88	6	190	34	207	8.4e-40	131.1	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
2918277530	432	86.32	3	432	61	464	1.4e-72	239.6	COG5338	Uncharacterized protein	468
2918277532	146	87.97	14	146	11	127	1.3e-25	84.6	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918277533	406	95.63	18	388	3	352	1.4e-57	189.9	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918277534	613	89.78	1	294	30	319	2.8e-89	87.1	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918277534	613	97.52	306	609	6	320	2.8e-89	213.4	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918277535	247	98.03	1	245	6	254	1.4e-82	271.4	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2918277536	243	99.58	9	243	2	237	2.1e-91	299.9	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2918277537	120	15.38	2	89	76	91	1.4e-01	2.5	COG5572	Uncharacterized membrane protein	104
2918277537	120	26.92	85	120	44	71	1.4e-01	6.6	COG5572	Uncharacterized membrane protein	104
2918277539	274	89.18	23	273	17	255	2.8e-49	162.3	COG1877	Trehalose-6-phosphatase	266
2918277541	378	99.21	1	377	2	379	0.0e+00	447.1	COG1820	N-acetylglucosamine-6-phosphate deacetylase	380
2918277542	82	36	6	76	64	108	2.7e-04	15.9	COG2198	HPt (histidine-containing phosphotransfer) domain	122
2918277543	301	95.16	1	299	7	301	8.2e-78	256.2	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
2918277545	473	97.61	8	471	10	417	5.7e-84	277.2	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
2918277546	231	98.31	1	231	3	235	8.3e-89	291.4	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2918277547	248	96.09	1	248	8	253	3.7e-121	398	COG4674	ABC-type uncharacterized transport system, ATPase component	249
2918277548	379	97.21	11	362	6	319	3.6e-89	293.7	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918277549	533	98.01	233	531	5	299	2.0e-101	333.7	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2918277550	431	98.36	22	389	1	360	3.0e-69	228.2	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918277554	567	15.65	452	567	651	771	1.1e-78	44.1	COG4993	Glucose dehydrogenase	773
2918277554	567	44.63	3	392	151	495	1.1e-78	221.8	COG4993	Glucose dehydrogenase	773
2918277557	201	96.39	2	198	3	189	1.1e-71	235.3	COG3644	Uncharacterized protein	194
2918277558	722	61.7	583	709	48	134	5.9e-17	34.7	COG4642	Uncharacterized conserved protein	139
2918277558	722	64.54	517	676	43	133	5.9e-17	36.6	COG4642	Uncharacterized conserved protein	139
2918277559	903	83.48	634	903	55	332	6.4e-67	220.4	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
2918277562	265	96.81	8	264	5	247	2.8e-92	303.3	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2918277563	282	87.21	4	272	26	250	9.6e-56	183.5	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2918277564	384	95.35	125	382	11	256	4.1e-64	211.3	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2918277565	333	88.36	1	332	11	306	7.5e-40	129.3	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918277566	139	47.33	41	138	57	118	9.6e-11	36.1	COG1917	Cupin domain protein related to quercetin dioxygenase	131
2918277567	1802	24.64	103	278	1	136	4.7e-124	83.6	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
2918277567	1802	54.98	1512	1759	135	316	7.9e-50	21.2	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2918277567	1802	74.02	1210	1511	8	252	7.9e-50	137.9	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2918277567	1802	78.08	306	817	122	552	4.7e-124	321.4	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
2918277567	1802	96.6	850	1167	7	262	1.2e-61	203.3	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918277568	99	23.11	26	98	59	113	6.5e-13	43.6	COG3409	Peptidoglycan-binding (PGRP) domain of peptidoglycan hydrolases	185
2918277569	319	99.58	72	310	1	238	5.3e-113	370.9	COG1186	Protein chain release factor B	239
2918277570	479	96.96	2	433	2	416	3.4e-95	313.9	COG1696	D-alanyl-lipoteichoic acid acyltransferase DltB, MBOAT superfamily	425
2918277572	382	62.05	2	136	62	182	2.3e-14	28.7	COG3861	Stress response protein YsnF (function unknown)	195
2918277572	382	67.18	190	381	52	182	2.3e-14	25.1	COG3861	Stress response protein YsnF (function unknown)	195
2918277573	847	96.48	1	795	2	768	0.0e+00	962.1	COG5009	Membrane carboxypeptidase/penicillin-binding protein	797
2918277574	440	91.35	55	433	22	264	2.8e-71	234.6	COG0860	N-acetylmuramoyl-L-alanine amidase	231
2918277575	1014	99.39	2	639	2	487	0.0e+00	737.2	COG1530	Ribonuclease G or E	487
2918277576	185	99.34	31	182	1	151	7.2e-50	163.5	COG0782	Transcription elongation factor, GreA/GreB family	151
2918277577	203	84.85	1	196	1	196	9.3e-32	105.3	COG1011	FMN phosphatase YigB, HAD superfamily	229
2918277578	252	97.59	7	251	7	249	2.9e-54	178.8	COG1651	Protein-disulfide isomerase	244
2918277579	448	85.15	17	446	57	469	2.9e-96	317.7	COG4783	Putative Zn-dependent protease, contains TPR repeats	484
2918277580	436	6.06	264	330	363	395	3.4e-35	13.9	COG0405	Gamma-glutamyltranspeptidase	539
2918277580	436	47.52	12	280	18	276	3.4e-35	98.8	COG0405	Gamma-glutamyltranspeptidase	539
2918277581	384	96.97	6	384	8	391	9.3e-106	348.7	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
2918277582	454	98.9	1	454	6	456	0.0e+00	653.8	COG3572	Gamma-glutamylcysteine synthetase	456
2918277583	264	97.97	10	247	5	245	1.8e-59	195.5	COG1385	16S rRNA U1498 N3-methylase RsmE	246
2918277584	959	71.07	428	815	110	389	1.4e-60	200.7	COG0642	Signal transduction histidine kinase	336
2918277585	307	96.9	21	307	7	287	1.4e-88	291.2	COG0382	4-hydroxybenzoate polyprenyltransferase	289
2918277587	218	96.35	1	216	8	218	8.3e-72	235.6	COG3897	Predicted nicotinamide N-methyase	218
2918277588	261	72.46	129	261	22	142	1.8e-22	74.2	COG4335	3-methyladenine DNA glycosylase AlkC	167
2918277589	503	99.59	1	496	1	481	0.0e+00	707	COG0043	3-polyprenyl-4-hydroxybenzoate decarboxylase	477
2918277591	142	88.89	1	131	8	135	3.3e-21	70.7	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
2918277592	400	47.26	206	396	10	190	1.5e-36	17.7	COG0477	MFS family permease	338
2918277592	400	63.45	3	235	4	246	1.5e-36	105.6	COG0477	MFS family permease	338
2918277593	451	99.12	10	451	4	455	1.9e-121	400.5	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
2918277594	139	14.81	102	139	120	147	2.7e-06	7.8	COG3945	Hemerythrin-like domain	189
2918277594	139	41.27	1	94	87	164	2.7e-06	12.8	COG3945	Hemerythrin-like domain	189
2918277597	315	97.02	18	314	3	295	6.6e-60	197.1	COG1597	Diacylglycerol kinase family enzyme	301
2918277598	269	99.59	13	250	1	240	2.2e-70	231.4	COG2908	UDP-2,3-diacylglucosamine pyrophosphatase LpxH	237
2918277599	332	97.56	1	329	2	400	3.3e-38	126.9	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918277600	427	99.52	2	418	2	417	5.0e-130	428.4	COG1519	3-deoxy-D-manno-octulosonic-acid transferase	419
2918277601	332	94.94	1	326	5	323	2.8e-87	287.5	COG1663	Tetraacyldisaccharide-1-P 4'-kinase	336
2918277602	302	90.26	6	302	20	297	3.8e-74	244.2	COG1560	Lauroyl/myristoyl acyltransferase	308
2918277603	217	97.6	5	214	4	206	1.1e-57	189.2	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
2918277604	130	99.15	8	130	2	118	6.5e-35	114.8	COG3761	NADH:ubiquinone oxidoreductase 17.2 kD subunit	118
2918277605	162	38.92	1	152	10	153	1.0e-38	128	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2918277606	248	51.97	2	238	43	187	2.0e-19	65.1	COG0500	SAM-dependent methyltransferase	257
2918277608	137	71.95	9	136	36	153	3.4e-37	122.4	COG4765	Uncharacterized protein	164
2918277609	212	86.43	2	202	23	213	8.9e-81	264.3	COG2360	Leu/Phe-tRNA-protein transferase	221
2918277610	217	84	1	217	36	245	1.1e-58	193.3	COG3719	Ribonuclease I	249
2918277611	325	67.74	116	305	66	212	5.7e-61	200.1	COG5637	Uncharacterized membrane protein	217
2918277612	389	99.15	1	389	3	352	1.4e-121	400.1	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
2918277613	446	68.58	1	446	1	443	0.0e+00	670.3	COG4770	Acetyl/propionyl-CoA carboxylase, alpha subunit	645
2918277614	148	98.64	11	148	2	146	6.9e-39	128.5	COG0511	Biotin carboxyl carrier protein	140
2918277615	149	97.95	5	149	2	144	3.4e-65	212.7	COG0757	3-dehydroquinate dehydratase	146
2918277616	264	95.05	1	261	1	269	9.3e-22	72	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918277619	33	4.89	1	33	506	537	1.2e-01	6	COG5180	PAB1-binding protein PBP1, interacts with poly(A)-binding protein	654
2918277620	289	93.31	2	284	20	298	9.7e-102	335	COG1230	Co/Zn/Cd efflux system component	296
2918277623	810	12	379	451	99	149	3.8e-113	6.1	COG0840	Methyl-accepting chemotaxis protein	408
2918277623	810	15.76	184	281	183	249	3.8e-113	4	COG0840	Methyl-accepting chemotaxis protein	408
2918277623	810	23.53	255	382	44	143	3.8e-113	38.8	COG0840	Methyl-accepting chemotaxis protein	408
2918277623	810	78.12	436	743	94	425	3.8e-113	339.6	COG0840	Methyl-accepting chemotaxis protein	408
2918277624	182	58.46	1	110	15	90	1.2e-12	42.9	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918277626	192	88.65	14	192	19	182	1.7e-55	182.5	COG3108	Uncharacterized conserved protein YcbK, DUF882 family	185
2918277627	400	56	10	369	225	546	1.4e-79	263	COG2989	Murein L,D-transpeptidase YcbB/YkuD	561
2918277628	194	89.09	3	123	2	99	2.0e-09	31.1	COG1544	Ribosome-associated translation inhibitor RaiA	110
2918277628	194	92.54	119	184	3	64	1.4e-07	25.4	COG1278	Cold shock protein, CspA family	67
2918277630	343	86.81	207	337	2	126	2.4e-30	99.5	COG2703	Hemerythrin	144
2918277631	406	74.25	156	386	65	263	7.6e-45	147.8	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
2918277634	375	72.08	9	373	103	386	2.5e-47	156.9	COG0642	Signal transduction histidine kinase	336
2918277635	685	93.34	19	677	3	605	5.8e-113	372.8	COG3408	Glycogen debranching enzyme (alpha-1,6-glucosidase)	641
2918277636	645	82.62	13	552	38	560	0.0e+00	456.8	COG0296	1,4-alpha-glucan branching enzyme	628
2918277637	245	87.36	5	244	4	231	3.0e-110	362.2	COG4813	Trehalose utilization protein	261
2918277639	391	99.72	1	391	2	353	2.8e-104	343.2	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
2918277640	251	95.85	5	244	9	216	3.8e-47	152.5	COG5637	Uncharacterized membrane protein	217
2918277643	214	15.25	44	148	88	132	1.0e-13	18.5	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918277643	214	22.03	143	210	229	293	1.0e-13	28.3	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918277644	120	90.62	1	120	7	122	8.5e-34	110.6	COG1380	Putative effector of murein hydrolase LrgA, UPF0299 family	128
2918277645	240	97.83	11	240	5	229	1.2e-77	254.9	COG1346	Putative effector of murein hydrolase	230
2918277646	567	97.34	40	478	1	402	6.8e-130	428.1	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
2918277647	328	98.75	1	325	2	318	8.2e-65	214	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2918277648	267	94.1	1	266	6	276	3.6e-92	302.9	COG0682	Prolipoprotein diacylglyceryltransferase	287
2918277649	371	95.41	6	369	7	359	6.7e-107	352.1	COG1565	SAM-dependent methyltransferase, MidA family	370
2918277650	256	96.41	2	255	9	250	1.1e-77	255.4	COG1496	Copper oxidase (laccase) domain	249
2918277651	139	90.28	1	138	1	130	3.6e-19	63.6	COG2703	Hemerythrin	144
2918277652	311	98.11	1	311	6	317	2.0e-122	403	COG0462	Phosphoribosylpyrophosphate synthetase	314
2918277653	201	96.77	4	97	4	93	2.9e-29	95.5	COG1825	Ribosomal protein L25 (general stress protein Ctc)	93
2918277654	191	97.88	1	187	2	186	1.6e-72	237.6	COG0193	Peptidyl-tRNA hydrolase	190
2918277655	208	44.77	2	158	41	147	3.0e-08	24.1	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
2918277656	366	100	1	366	1	372	0.0e+00	494.1	COG0012	Ribosome-binding ATPase YchF, GTP1/OBG family	372
2918277657	283	96.89	24	280	4	252	5.8e-88	288.7	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
2918277658	157	90.41	14	156	6	137	1.2e-25	84.6	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
2918277659	309	98.34	1	299	1	296	4.3e-54	178.9	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918277660	418	85.32	39	411	49	385	1.1e-18	61.9	COG2814	Predicted arabinose efflux permease, MFS family	394
2918277662	240	97.76	1	238	6	267	6.8e-70	230.3	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918277663	391	99.75	1	391	1	393	0.0e+00	489.7	COG0183	Acetyl-CoA acetyltransferase	392
2918277664	416	62.17	125	416	111	391	3.2e-51	168.8	COG3243	Poly(3-hydroxyalkanoate) synthetase	445
2918277665	209	97.41	2	198	4	191	2.7e-72	237.4	COG5394	Polyhydroxyalkanoate (PHA) synthesis regulator protein, binds DNA and PHA	193
2918277667	390	98.24	1	390	6	395	1.4e-57	189.8	COG0754	Glutathionylspermidine synthase	387
2918277672	412	65.88	235	403	17	155	1.2e-23	13.3	COG2391	Uncharacterized membrane protein YedE/YeeE, contains two sulfur transport domains	198
2918277672	412	91.47	19	224	15	207	1.2e-23	71.2	COG2391	Uncharacterized membrane protein YedE/YeeE, contains two sulfur transport domains	198
2918277673	317	97.4	14	302	6	305	1.0e-41	137.6	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
2918277674	331	98.37	14	320	4	304	1.3e-91	301.8	COG1131	ABC-type multidrug transport system, ATPase component	293
2918277675	59	75.81	1	51	15	61	1.0e-16	55.2	COG4391	Uncharacterized conserved protein, contains Zn-finger domain	62
2918277676	702	63.8	179	700	217	639	9.0e-112	368.8	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2918277677	972	92.66	26	323	13	315	1.6e-82	271.5	COG0258	5'-3' exonuclease	310
2918277677	972	99.83	360	972	2	597	0.0e+00	756.6	COG0749	DNA polymerase I - 3'-5' exonuclease and polymerase domains	593
2918277678	275	83.96	5	256	2	226	5.5e-46	151.9	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918277680	332	92.63	4	328	14	340	9.2e-80	262.6	COG1744	Basic membrane lipoprotein Med, periplasmic binding protein (PBP1-ABC) superfamily	345
2918277682	395	29.88	124	209	93	167	1.3e-60	48.9	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2918277682	395	38.25	21	136	129	224	1.3e-60	72.5	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2918277682	395	64.54	214	392	58	219	1.3e-60	87.9	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2918277683	244	80.58	32	211	8	173	1.8e-15	51.6	COG1335	Nicotinamidase-related amidase	205
2918277685	205	12.68	2	154	229	315	1.2e-04	15.2	COG1289	Uncharacterized membrane protein YccC	674
2918277686	466	95.82	3	456	15	472	1.8e-123	407.3	COG1109	Phosphomannomutase	464
2918277687	441	99.76	1	419	1	417	0.0e+00	532.8	COG1004	UDP-glucose 6-dehydrogenase	414
2918277688	289	97.59	2	289	3	285	7.5e-118	387.4	COG1210	UTP-glucose-1-phosphate uridylyltransferase	291
2918277691	233	75.34	2	220	72	291	2.5e-53	175.9	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
2918277692	377	90.37	8	353	26	344	1.8e-34	113.7	COG1744	Basic membrane lipoprotein Med, periplasmic binding protein (PBP1-ABC) superfamily	345
2918277695	461	92.29	3	415	5	399	8.7e-101	332.3	COG1696	D-alanyl-lipoteichoic acid acyltransferase DltB, MBOAT superfamily	425
2918277696	155	80.3	19	138	3	108	7.2e-25	81.8	COG1833	Uri superfamily endonuclease	132
2918277697	643	81.73	216	639	66	387	1.1e-73	242.9	COG0642	Signal transduction histidine kinase	336
2918277698	256	95.85	2	238	7	237	2.4e-56	185.2	COG2186	DNA-binding transcriptional regulator, FadR family	241
2918277699	557	99.62	11	551	2	526	0.0e+00	610.2	COG1620	L-lactate permease	522
2918277700	957	93.77	534	939	8	383	2.0e-50	165	COG0247	Fe-S oxidoreductase	388
2918277700	957	99.36	12	521	2	467	9.1e-100	329	COG0277	FAD/FMN-containing dehydrogenase	459
2918277701	253	59.85	4	253	159	398	1.3e-64	213.2	COG0247	Fe-S oxidoreductase	388
2918277702	474	98.91	2	466	4	458	0.0e+00	558.9	COG1139	L-lactate utilization protein LutB, contains a ferredoxin-type domain	459
2918277703	224	97.76	7	224	4	221	2.7e-39	130	COG1556	L-lactate utilization protein LutC, contains LUD domain	218
2918277704	235	81.38	3	217	34	234	1.6e-46	152.9	COG5530	Uncharacterized membrane protein	247
2918277705	370	95.36	1	368	1	370	1.3e-88	292.2	COG1748	Saccharopine dehydrogenase, NADP-dependent	389
2918277706	141	89.87	1	140	6	147	3.4e-31	103	COG1522	DNA-binding transcriptional regulator, Lrp family	154
2918277707	552	98.92	1	550	1	549	0.0e+00	579.3	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
2918277708	499	97.08	11	487	13	477	0.0e+00	463.5	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918277710	489	99.37	12	488	3	473	0.0e+00	589.7	COG0246	Mannitol-1-phosphate/altronate dehydrogenases	473
2918277711	341	98.29	2	341	4	348	3.7e-76	251.5	COG0673	Predicted dehydrogenase	342
2918277712	292	96.68	6	290	8	298	1.2e-43	144.1	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918277713	149	72.63	1	141	52	189	5.5e-17	56.6	COG3009	Uncharacterized lipoprotein YmbA	190
2918277714	337	21.08	1	86	3	80	2.1e-12	35.5	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2918277714	337	21.89	114	245	137	217	2.1e-12	1.5	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2918277714	337	31.89	193	331	144	261	2.1e-12	13.4	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2918277715	269	93.92	13	269	6	252	5.4e-87	285.9	COG1127	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, ATPase component MlaF	263
2918277716	375	92.88	111	374	15	262	6.7e-69	226.4	COG0767	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, permease component MlaE	267
2918277717	98	24.12	19	87	59	99	4.2e-05	18.2	COG4803	Uncharacterized membrane protein	170
2918277720	419	54.55	78	377	14	187	3.7e-17	57.2	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
2918277722	374	94.17	17	372	10	348	2.1e-68	225.4	COG0628	Predicted PurR-regulated permease PerM	355
2918277723	123	66.18	23	122	44	133	5.2e-06	21.1	COG4520	Surface antigen	136
2918277725	709	82.75	379	694	34	316	1.0e-56	187.4	COG0668	Small-conductance mechanosensitive channel	316
2918277726	1041	99.9	5	1009	1	1013	0.0e+00	924.5	COG0841	Multidrug efflux pump subunit AcrB	1009
2918277727	381	95.38	7	374	8	379	1.0e-54	180.6	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918277728	365	94.36	1	363	18	385	6.6e-57	188	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918277729	394	99.25	3	391	2	396	5.9e-123	404.8	COG0282	Acetate kinase	396
2918277730	319	14.68	26	90	22	69	4.3e-68	14.1	COG0280	Phosphotransacetylase	327
2918277730	319	66.97	84	311	105	323	4.3e-68	208.7	COG0280	Phosphotransacetylase	327
2918277733	302	87.12	16	275	21	250	1.9e-47	156.2	COG3900	Predicted periplasmic protein	262
2918277737	643	87.5	215	364	18	150	1.4e-27	89.8	COG5616	TolB amino-terminal domain (function unknown)	152
2918277738	139	15.95	23	66	130	155	2.2e-06	14.1	COG5126	Ca2+-binding protein, EF-hand superfamily	160
2918277738	139	18.4	64	139	109	138	2.2e-06	6.1	COG5126	Ca2+-binding protein, EF-hand superfamily	160
2918277740	67	21.14	2	63	7	32	2.9e-03	12.6	COG5633	Uncharacterized conserved protein YcfL	123
2918277742	516	65.48	12	367	133	390	6.5e-53	174.9	COG0642	Signal transduction histidine kinase	336
2918277743	246	97.36	20	245	5	225	8.6e-53	174	COG1451	Predicted metal-dependent hydrolase	223
2918277744	394	47	205	393	7	186	1.7e-33	15.2	COG0477	MFS family permease	338
2918277744	394	49.61	5	207	8	197	1.7e-33	101.6	COG0477	MFS family permease	338
2918277745	162	63.72	3	161	3	146	9.8e-43	141	COG1285	Uncharacterized membrane protein YhiD, involved in acid resistance	221
2918277746	378	94.18	4	378	23	394	6.6e-109	358.7	COG0019	Diaminopimelate decarboxylase	394
2918277747	71	69.84	13	70	19	62	6.5e-16	52.6	COG5457	Uncharacterized conserved protein YjiS, DUF1127 family	63
2918277748	387	92.68	12	387	26	392	1.4e-106	351.4	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
2918277749	227	98.27	1	227	3	229	1.8e-28	94.7	COG1011	FMN phosphatase YigB, HAD superfamily	229
2918277750	114	89.66	1	113	12	115	9.3e-38	123.4	COG3450	Predicted enzyme of the cupin superfamily	116
2918277752	134	97.5	13	132	2	118	3.3e-51	166.9	COG3536	Uncharacterized conserved protein, DUF971 family	120
2918277753	83	92.42	24	82	1	61	3.2e-24	79.1	COG2835	Uncharacterized conserved protein YbaR, Trm112 family	60
2918277754	223	91.86	8	219	5	207	3.9e-59	194.9	COG2802	Uncharacterized protein, similar to the N-terminal domain of Lon protease	221
2918277755	323	93.77	13	322	20	305	7.6e-101	332.3	COG3118	Negative regulator of GroEL, contains thioredoxin-like and TPR-like domains	304
2918277756	183	96.34	19	181	5	162	1.8e-62	204.6	COG3760	Uncharacterized protein	164
2918277758	228	93.4	8	217	12	209	2.0e-49	162.6	COG0684	Regulator of RNase E activity RraA	210
2918277759	565	86.82	104	560	55	423	2.8e-58	192.3	COG0840	Methyl-accepting chemotaxis protein	408
2918277760	323	98.75	3	323	3	317	5.7e-90	296.3	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918277761	692	76.14	160	555	92	391	7.7e-53	174.7	COG0642	Signal transduction histidine kinase	336
2918277761	692	89.47	567	692	8	126	8.0e-19	61.3	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918277762	1614	98.12	2	1614	28	1590	0.0e+00	2031.8	COG2902	NAD-specific glutamate dehydrogenase	1592
2918277764	544	37.97	277	429	30	100	9.1e-06	18.9	COG2242	Precorrin-6B methylase 2	187
2918277764	544	76.09	5	291	38	317	4.6e-25	82.2	COG0457	Tetratricopeptide (TPR) repeat	291
2918277765	439	95.36	4	436	13	444	2.3e-121	400.1	COG2270	MFS-type transporter involved in bile tolerance, Atg22 family	438
2918277767	534	99.81	16	534	2	515	0.0e+00	745.8	COG0138	AICAR transformylase/IMP cyclohydrolase PurH	515
2918277768	556	95.76	7	554	23	564	1.0e-125	414.9	COG5360	Uncharacterized conserved protein, heparinase superfamily	566
2918277769	438	99.16	102	436	2	356	6.0e-88	290.1	COG0144	16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family	355
2918277771	310	91.59	1	310	23	327	6.7e-18	54.5	COG0618	nanoRNase/pAp phosphatase, hydrolyzes c-di-AMP and oligoRNAs	332
2918277772	296	90.71	1	287	25	307	6.0e-79	260.2	COG0501	Zn-dependent protease with chaperone function	302
2918277773	69	73.81	1	69	23	84	2.8e-17	58.1	COG5508	Uncharacterized protein	84
2918277774	431	41.43	130	250	123	226	1.1e-75	95.1	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2918277774	431	49	254	413	63	185	1.1e-75	97.8	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2918277774	431	53.78	28	136	60	194	1.1e-75	67	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2918277775	154	63.92	3	149	25	148	2.1e-17	57.4	COG1525	Endonuclease YncB, thermonuclease family	192
2918277776	283	76.15	8	281	20	217	5.4e-25	82.8	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2918277777	646	100	67	628	1	552	0.0e+00	832	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
2918277778	79	7.29	17	76	285	315	1.5e-03	12.6	COG0840	Methyl-accepting chemotaxis protein	408
2918277779	137	94.87	1	137	4	151	8.4e-45	144.1	COG2947	Predicted RNA-binding protein, contains PUA-like domain	156
2918277780	94	100	1	91	1	92	1.0e-22	75.1	COG2350	Uncharacterized conserved protein YciI, contains a putative active-site phosphohistidine	92
2918277782	339	98.78	9	337	3	327	1.0e-116	384.4	COG0240	Glycerol-3-phosphate dehydrogenase	329
2918277783	357	98.55	1	345	1	339	0.0e+00	434.1	COG0533	tRNA A37 threonylcarbamoyltransferase TsaD	342
2918277784	280	72.04	3	273	29	229	1.7e-15	52.3	COG0500	SAM-dependent methyltransferase	257
2918277785	308	95.77	2	305	2	295	1.3e-110	363.9	COG0181	Porphobilinogen deaminase	307
2918277786	254	89.2	8	247	3	225	1.9e-32	106.9	COG1587	Uroporphyrinogen-III synthase	248
2918277787	595	98.1	91	578	7	420	4.6e-21	65.7	COG4223	Uncharacterized conserved protein	422
2918277788	456	84.56	1	456	1	449	1.4e-110	365.4	COG3898	Uncharacterized membrane-anchored protein	531
2918277790	208	93.57	1	170	4	163	1.3e-44	146.6	COG3153	Predicted N-acetyltransferase YhbS	171
2918277791	130	96.83	2	127	3	124	1.7e-53	174.5	COG2967	Uncharacterized protein affecting Mg2+/Co2+ transport	126
2918277792	226	94.42	24	221	10	195	3.6e-79	259.1	COG0302	GTP cyclohydrolase I	195
2918277793	190	10.28	132	190	413	460	2.1e-24	28.2	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2918277793	190	27.19	1	140	5	131	2.1e-24	51.4	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2918277794	160	96.77	5	159	2	151	1.9e-49	161.9	COG2606	Cys-tRNA(Pro) deacylase, prolyl-tRNA editing enzyme YbaK/EbsC	155
2918277796	502	99.61	1	496	2	510	0.0e+00	620.3	COG0427	Acyl-CoA hydrolase	501
2918277797	511	69.29	3	331	105	359	1.3e-23	71.6	COG0457	Tetratricopeptide (TPR) repeat	291
2918277800	434	96.97	5	434	7	422	3.6e-127	419.5	COG0285	Folylpolyglutamate synthase/Dihydropteroate synthase	427
2918277801	327	90.14	1	290	18	282	2.8e-117	385.6	COG0777	Acetyl-CoA carboxylase beta subunit	294
2918277802	278	98.87	5	275	3	264	7.3e-98	321.4	COG0159	Tryptophan synthase alpha chain	265
2918277803	405	98.23	9	405	3	391	0.0e+00	667.8	COG0133	Tryptophan synthase beta chain	396
2918277804	209	88.04	1	207	19	202	1.0e-17	60.3	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918277806	347	98.9	1	347	1	358	0.0e+00	475.3	COG1312	D-mannonate dehydratase	362
2918277807	231	93.36	1	230	7	231	4.6e-62	204.2	COG2186	DNA-binding transcriptional regulator, FadR family	241
2918277808	800	12.94	749	800	339	389	4.2e-39	29.9	COG0642	Signal transduction histidine kinase	336
2918277808	800	48.98	422	737	128	320	4.2e-39	101.3	COG0642	Signal transduction histidine kinase	336
2918277809	446	99.27	12	419	2	408	5.6e-129	425.2	COG1252	NADH dehydrogenase, FAD-containing subunit	405
2918277810	168	25	2	165	354	493	5.1e-12	39.9	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918277811	453	84.26	98	453	56	387	1.7e-57	190.6	COG0642	Signal transduction histidine kinase	336
2918277812	242	98.71	5	238	2	230	6.5e-84	275.5	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918277814	340	97.07	5	324	3	300	5.4e-67	220.5	COG0492	Thioredoxin reductase	305
2918277815	159	95.97	8	156	2	144	1.2e-40	133.4	COG0802	tRNA A37 threonylcarbamoyladenosine biosynthesis protein TsaE	149
2918277816	338	88.89	3	331	32	343	8.1e-74	243	COG3178	Predicted phosphotransferase, aminoglycoside/choline kinase (APH/ChoK) family	351
2918277817	251	63.23	12	248	2	240	2.6e-47	155.8	COG1208	NDP-sugar pyrophosphorylase, includes eIF-2Bgamma, eIF-2Bepsilon, and LPS biosynthesis proteins	358
2918277818	991	99.57	7	707	2	696	0.0e+00	531	COG3893	Inactivated superfamily I helicase	697
2918277818	991	99.63	720	989	1	268	6.8e-36	117.9	COG2887	RecB family exonuclease	269
2918277819	1175	99.39	12	1159	7	1151	0.0e+00	670.1	COG1074	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)	1139
2918277820	108	34.43	1	108	26	130	9.3e-32	105.6	COG3118	Negative regulator of GroEL, contains thioredoxin-like and TPR-like domains	304
2918277821	294	98.34	6	294	2	297	1.7e-69	229.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918277822	63	87.3	2	62	8	62	1.4e-19	64.4	COG5457	Uncharacterized conserved protein YjiS, DUF1127 family	63
2918277823	388	76.14	12	388	88	387	2.3e-35	117.6	COG0642	Signal transduction histidine kinase	336
2918277824	282	77.97	44	281	60	282	2.3e-44	146.2	COG3001	Fructosamine-3-kinase	286
2918277825	157	98.65	1	153	2	147	2.4e-43	142.5	COG0394	Protein-tyrosine-phosphatase	139
2918277826	243	96.89	1	242	4	252	6.9e-71	232.8	COG0846	NAD-dependent protein deacetylase, SIR2 family	250
2918277827	195	96.04	1	192	8	201	3.8e-54	177.8	COG1573	Uracil-DNA glycosylase	202
2918277828	253	63.8	2	252	31	208	6.4e-14	47.1	COG0500	SAM-dependent methyltransferase	257
2918277829	122	87.5	1	122	15	133	1.3e-45	149.3	COG3824	Predicted Zn-dependent protease, minimal metalloprotease (MMP)-like domain	136
2918277830	100	92.08	1	98	4	96	5.5e-29	94.8	COG2154	Pterin-4a-carbinolamine dehydratase	101
2918277831	470	74.33	30	394	36	342	5.2e-37	121.9	COG1373	Predicted ATPase, AAA+ superfamily	398
2918277833	330	90.55	5	330	32	328	7.2e-66	216.8	COG0598	Mg2+ and Co2+ transporter CorA	322
2918277834	301	98.94	5	293	1	281	9.5e-115	376.9	COG0190	5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase	283
2918277835	114	95.1	5	108	5	101	2.2e-27	89.6	COG1872	Uncharacterized conserved protein YggU, UPF0235/DUF167 family	102
2918277836	94	86.46	4	92	4	86	7.4e-24	78.6	COG0762	Uncharacterized conserved protein YggT, Ycf19 family	96
2918277838	229	99.12	1	227	2	227	1.9e-88	290.4	COG4160	ABC-type arginine/histidine transport system, permease component	228
2918277839	213	93.04	1	213	16	229	4.3e-80	263	COG4215	ABC-type arginine transport system, permease component	230
2918277840	284	95.05	4	284	9	277	3.6e-63	208.1	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918277841	268	97.66	10	264	5	254	0.0e+00	438.9	COG4598	ABC-type histidine transport system, ATPase component	256
2918277842	559	98.16	13	559	10	543	0.0e+00	608.6	COG2985	Uncharacterized membrane protein YbjL, putative transporter	544
2918277843	224	93.3	3	208	6	200	1.6e-62	205.3	COG4133	ABC-type transport system involved in cytochrome c biogenesis, ATPase component	209
2918277844	221	99.55	1	221	1	220	2.8e-80	263.7	COG2386	ABC-type transport system involved in cytochrome c biogenesis, permease component	221
2918277846	239	81.56	1	237	40	269	3.4e-64	211.6	COG0755	ABC-type transport system involved in cytochrome c biogenesis, permease component	281
2918277847	76	82.09	1	67	7	61	1.3e-14	48.5	COG3114	Heme exporter protein D	67
2918277848	155	94.77	1	151	1	145	3.2e-53	173.9	COG2332	Cytochrome c-type biogenesis protein CcmE	153
2918277849	663	99.07	1	656	2	641	0.0e+00	802	COG1138	Cytochrome c biogenesis factor	648
2918277850	178	95.33	5	154	4	146	6.7e-12	40.4	COG0526	Thiol-disulfide isomerase or thioredoxin	127
2918277851	172	97.39	3	165	4	152	6.9e-48	156.4	COG3088	Cytochrome c-type biogenesis protein CcmH/NrfF	153
2918277852	461	53.29	287	459	120	273	5.1e-85	75.6	COG4235	Cytochrome c-type biogenesis protein CcmH/NrfG	287
2918277852	461	97.92	1	286	1	283	5.1e-85	210.6	COG4235	Cytochrome c-type biogenesis protein CcmH/NrfG	287
2918277853	558	94.74	319	558	8	223	3.0e-56	184.4	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
2918277854	134	92.24	18	132	7	113	1.8e-29	96.7	COG3339	Uncharacterized membrane protein YkvA, DUF1232 family	116
2918277855	133	95.61	15	130	4	112	2.6e-18	60.5	COG0607	Rhodanese-related sulfurtransferase	110
2918277856	144	98.63	3	128	2	145	2.1e-14	49.5	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2918277857	411	98.76	6	411	3	400	0.0e+00	568.2	COG0137	Argininosuccinate synthase	403
2918277858	94	31.98	2	77	66	120	7.8e-03	10.6	COG1755	Uncharacterized protein YpbQ, isoprenylcysteine carboxyl methyltransferase (ICMT) family	172
2918277859	76	45.39	3	75	21	84	1.2e-03	13.7	COG1585	Membrane protein implicated in regulation of membrane protease activity	140
2918277860	869	87.82	432	862	45	390	1.3e-73	243.6	COG0642	Signal transduction histidine kinase	336
2918277861	286	97.67	5	285	2	295	2.8e-55	182.7	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918277863	239	92.21	3	152	9	150	4.9e-17	56.8	COG3133	Outer membrane lipoprotein SlyB	154
2918277864	336	91.26	160	336	10	176	2.0e-49	162	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2918277865	600	99.17	1	600	5	602	0.0e+00	1020.7	COG0481	Translation elongation factor EF-4, membrane-bound GTPase	603
2918277866	492	98.36	1	491	1	481	0.0e+00	530.5	COG0297	Glycogen synthase	487
2918277867	427	97.7	9	423	4	386	0.0e+00	516	COG0448	ADP-glucose pyrophosphorylase	393
2918277868	437	97.57	38	437	2	403	0.0e+00	537.7	COG0004	Ammonia channel protein AmtB	409
2918277869	409	42.62	9	179	56	159	5.1e-16	52.9	COG2227	2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase	243
2918277870	286	79.55	2	132	22	126	3.3e-23	76.2	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918277870	286	99.35	131	283	1	153	4.5e-39	127.9	COG3449	DNA gyrase inhibitor GyrI	154
2918277871	369	96.46	32	365	10	336	1.9e-110	363.5	COG4448	L-asparaginase II	339
2918277872	194	53.61	3	144	115	255	2.2e-19	64.1	COG0566	tRNA G18 (ribose-2'-O)-methylase SpoU	260
2918277873	220	98.61	5	220	2	214	8.0e-47	154.1	COG3806	Anti-sigma factor ChrR, cupin superfamily	216
2918277874	191	93.55	15	191	6	179	2.4e-42	139.4	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918277876	388	97.99	20	370	2	343	0.0e+00	471.2	COG0820	Adenine C2-methylase RlmN of 23S rRNA A2503 and tRNA A37	349
2918277877	300	77.42	3	295	67	330	1.0e-81	269.6	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
2918277879	166	96.99	3	166	2	162	2.1e-59	194.8	COG1329	RNA polymerase-interacting regulator, CarD/CdnL/TRCF family	166
2918277880	111	89.04	1	65	3	67	3.5e-17	56.8	COG1146	NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit	68
2918277881	295	97.34	1	288	1	293	7.3e-62	204.3	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918277882	391	93.42	3	385	20	388	3.3e-12	40.1	COG2814	Predicted arabinose efflux permease, MFS family	394
2918277883	204	63.08	1	201	33	208	1.6e-05	20.1	COG0500	SAM-dependent methyltransferase	257
2918277884	135	93.87	1	122	10	162	8.4e-25	82.6	COG0517	CBS domain	117
2918277885	244	96.09	1	244	7	252	2.2e-80	264.2	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
2918277886	144	88	18	115	8	95	9.1e-30	97.6	COG1188	Ribosomal 50S subunit-recycling heat shock protein, contains S4 domain	100
2918277887	837	61.15	52	495	2	319	1.7e-17	57.5	COG0513	Superfamily II DNA and RNA helicase	513
2918277889	627	99.36	1	626	3	624	0.0e+00	765.4	COG0326	Molecular chaperone, HSP90 family	623
2918277890	276	94.92	3	275	13	292	9.7e-29	95.5	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918277891	409	83.5	14	405	64	392	1.5e-69	230	COG0642	Signal transduction histidine kinase	336
2918277892	296	92.01	1	296	10	320	2.8e-45	150.1	COG1305	Transglutaminase-like enzyme, putative cysteine protease	319
2918277893	144	90.34	1	137	5	135	1.5e-41	136.3	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
2918277895	219	84.91	21	219	6	185	7.7e-27	88.5	COG0560	Phosphoserine phosphatase	212
2918277896	127	40.6	13	126	7	60	6.0e-07	22.4	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918277897	243	97.76	1	243	4	265	6.4e-56	183.7	COG1912	S-adenosylmethionine hydrolase (SAM-hydroxide adenosyltransferase)	268
2918277898	312	95.08	1	296	15	304	1.4e-68	225.9	COG0803	ABC-type Zn uptake system ZnuABC, Zn-binding component ZnuA	303
2918277899	265	91.73	22	264	6	238	4.2e-89	292.8	COG1121	ABC-type Mn2+/Zn2+ transport system, ATPase component	254
2918277900	400	97.1	8	296	7	274	3.3e-63	208.4	COG1108	ABC-type Mn2+/Zn2+ transport system, permease component	274
2918277901	330	95.29	1	306	12	274	7.8e-58	184.6	COG1108	ABC-type Mn2+/Zn2+ transport system, permease component	274
2918277902	1084	24.81	704	822	7	39	2.6e-41	7.7	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918277902	1084	56	970	1076	19	88	7.1e-09	29.4	COG2198	HPt (histidine-containing phosphotransfer) domain	122
2918277902	1084	65.48	290	698	135	392	9.3e-73	240.8	COG0642	Signal transduction histidine kinase	336
2918277902	1084	92.48	831	965	6	128	2.6e-41	118.5	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918277903	69	97.01	1	68	1	65	3.6e-32	105	COG1278	Cold shock protein, CspA family	67
2918277904	467	97	4	466	5	457	0.0e+00	530.1	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2918277905	410	99.25	6	406	2	399	0.0e+00	443.5	COG0452	Phosphopantothenoylcysteine synthetase/decarboxylase	392
2918277906	156	93.96	7	156	9	148	5.6e-56	182.9	COG0756	dUTPase	148
2918277907	273	91.61	18	272	21	271	1.1e-37	124.9	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
2918277908	143	89.21	1	141	12	135	3.3e-44	145	COG0848	Biopolymer transport protein ExbD	137
2918277909	282	99.07	62	272	1	214	3.6e-63	207.9	COG0811	Biopolymer transport protein ExbB/TolQ	216
2918277910	151	90	2	148	2	136	2.1e-32	106.8	COG1959	DNA-binding transcriptional regulator, IscR family	150
2918277911	319	99.34	10	312	2	301	6.5e-123	404.1	COG0031	Cysteine synthase	300
2918277912	268	38.58	124	201	55	103	4.3e-03	3.5	COG2372	Copper-binding protein CopC (methionine-rich)	127
2918277912	268	40.94	41	104	52	103	4.3e-03	6.6	COG2372	Copper-binding protein CopC (methionine-rich)	127
2918277913	262	97.32	2	253	4	257	1.5e-85	280.9	COG0476	Molybdopterin or thiamine biosynthesis adenylyltransferase	254
2918277914	145	97.87	4	145	4	141	1.6e-16	54.2	COG2210	Peroxiredoxin family protein	137
2918277916	234	98.28	7	233	3	230	1.1e-91	301	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918277917	246	88.16	1	228	9	224	7.7e-64	210	COG0704	Phosphate uptake regulator	240
2918277918	261	97.64	10	261	7	254	5.1e-127	417	COG1117	ABC-type phosphate transport system, ATPase component	253
2918277919	432	16.33	22	101	9	56	3.5e-83	5.1	COG0581	ABC-type phosphate transport system, permease component	292
2918277919	432	88.1	145	432	36	294	3.5e-83	270.3	COG0581	ABC-type phosphate transport system, permease component	292
2918277920	441	96.5	127	440	12	314	3.7e-98	322.7	COG0573	ABC-type phosphate transport system, permease component	310
2918277921	345	96.31	1	330	11	323	3.7e-61	201.7	COG0226	ABC-type phosphate transport system, periplasmic component	318
2918277922	504	85.53	10	497	56	392	3.5e-77	254.6	COG0642	Signal transduction histidine kinase	336
2918277923	366	24.29	2	136	308	443	5.9e-20	33.2	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918277923	366	38.21	150	365	301	514	5.9e-20	37.8	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918277924	756	94.57	2	434	16	433	0.0e+00	572.7	COG0281	Malic enzyme	432
2918277924	756	97.86	434	754	3	322	4.4e-100	329.1	COG0280	Phosphotransacetylase	327
2918277925	248	98.39	1	248	2	246	1.3e-65	216	COG1402	 Creatinine amidohydrolase/Fe(II)-dependent formamide hydrolase involved in riboflavin and F420 biosynthesis	250
2918277926	218	37.2	14	206	4	186	4.8e-57	188.4	COG0606	Predicted ATPase with chaperone activity	490
2918277929	313	10.89	40	118	26	53	2.0e-09	7.9	COG3568	Metal-dependent hydrolase, endonuclease/exonuclease/phosphatase family	259
2918277929	313	53.31	142	311	118	254	2.0e-09	21.4	COG3568	Metal-dependent hydrolase, endonuclease/exonuclease/phosphatase family	259
2918277932	126	76.15	8	122	1	99	6.0e-18	60.4	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918277942	90	33.9	8	71	58	97	4.2e-04	15.1	COG0292	Ribosomal protein L20	118
2918277943	364	56.49	174	308	16	89	2.9e-03	11.2	COG3676	Transposase and inactivated derivatives	126
2918277943	364	82.95	27	163	15	121	7.5e-09	29.6	COG3677	Transposase	129
2918277944	373	8.52	3	96	98	123	5.1e-07	14.5	COG2333	Metal-dependent hydrolase, beta-lactamase superfamily II	293
2918277944	373	24.26	123	253	159	232	5.1e-07	7	COG2333	Metal-dependent hydrolase, beta-lactamase superfamily II	293
2918277945	786	57.04	647	762	17	93	4.6e-06	20.6	COG1310	Proteasome lid subunit RPN8/RPN11, contains Jab1/MPN domain metalloenzyme (JAMM) motif	134
2918277951	296	58.13	1	294	202	487	3.6e-117	386.7	COG0606	Predicted ATPase with chaperone activity	490
2918277952	500	91.19	46	482	21	289	1.5e-27	87.8	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918277959	128	54.89	15	125	27	99	6.7e-16	52.4	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918277961	896	99.18	11	892	6	852	0.0e+00	968.1	COG0249	DNA mismatch repair ATPase MutS	843
2918277962	319	94.01	2	316	13	326	2.9e-52	172.2	COG1275	Tellurite resistance protein TehA and related permeases	329
2918277965	143	73.5	2	111	17	102	2.6e-10	34.6	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
2918277967	402	97.98	12	402	7	395	0.0e+00	434.7	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
2918277969	344	90.44	2	334	10	340	3.7e-27	89.8	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918277970	309	97.79	30	304	5	270	3.4e-94	309.5	COG0313	16S rRNA C1402 (ribose-2'-O) methylase RsmI	275
2918277971	122	95.61	11	122	5	113	1.9e-29	96.5	COG0792	Predicted endonuclease distantly related to archaeal Holliday junction resolvase	114
2918277972	277	92.22	7	277	11	259	2.6e-47	156	COG2912	Regulator of sirC expression, contains transglutaminase-like and TPR domains	269
2918277973	318	98.73	3	314	3	313	5.1e-90	296	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
2918277974	163	98.82	2	162	2	169	9.5e-45	147.1	COG0262	Dihydrofolate reductase	167
2918277975	385	89.76	2	385	38	414	1.7e-115	380.6	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
2918277976	199	96.41	9	199	3	190	1.6e-65	215	COG0127	Inosine/xanthosine triphosphate pyrophosphatase, all-alpha NTP-PPase family	194
2918277977	239	96.54	1	237	8	230	3.4e-95	312.4	COG0689	Ribonuclease PH	230
2918277978	346	97.97	2	346	3	340	3.6e-113	373.2	COG1420	Transcriptional regulator of heat shock response	346
2918277979	209	96.94	1	196	6	195	4.4e-59	194.3	COG0576	Molecular chaperone GrpE (heat shock protein)	193
2918277980	121	49.57	3	120	2	116	1.3e-34	114.1	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918277985	641	99.17	1	600	5	605	0.0e+00	883	COG0443	Molecular chaperone DnaK (HSP70)	579
2918277986	388	99.74	1	385	1	384	0.0e+00	495	COG0484	DnaJ-class molecular chaperone with C-terminal Zn finger domain	371
2918277987	191	89.95	1	191	14	201	1.4e-12	43.5	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918277988	149	31.18	9	50	47	75	2.9e-27	3.8	COG4891	Uncharacterized protein	93
2918277988	149	96.77	51	143	3	92	2.9e-27	84	COG4891	Uncharacterized protein	93
2918277989	376	90.16	188	367	17	181	3.9e-44	144.9	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2918277990	240	94.4	3	240	13	231	2.8e-77	253.9	COG0670	Integral membrane protein, interacts with FtsH	233
2918277991	841	99.52	1	841	4	828	0.0e+00	827.2	COG3127	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component	829
2918277992	244	98.68	6	231	3	227	7.7e-102	334.1	COG4181	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component	228
2918277993	198	96.83	2	193	5	218	3.0e-42	139.7	COG2755	Lysophospholipase L1 or related esterase	216
2918277994	390	89.97	10	390	36	385	1.7e-48	159.9	COG4398	Small ligand-binding sensory domain FIST	389
2918277995	347	100	1	347	1	320	1.3e-113	373.4	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
2918277996	178	98.35	2	178	2	180	8.0e-52	170.3	COG1514	2'-5' RNA ligase	180
2918277997	420	99.49	16	409	2	392	3.4e-100	330.8	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2918277998	112	100	1	112	1	112	8.9e-49	159.3	COG0347	Nitrogen regulatory protein PII	112
2918277999	415	97.47	14	415	7	392	4.1e-72	237.9	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
2918278000	831	14.7	43	216	30	166	0.0e+00	13.2	COG1674	DNA segregation ATPase FtsK/SpoIIIE and related proteins	858
2918278000	831	53.65	218	830	427	926	0.0e+00	784.3	COG1674	DNA segregation ATPase FtsK/SpoIIIE and related proteins	858
2918278001	217	92.96	1	210	8	205	6.0e-24	79.4	COG2834	Outer membrane lipoprotein-sorting protein	211
2918278002	206	97.85	4	190	3	184	2.5e-33	109.6	COG3247	Uncharacterized membrane protein HdeD, DUF308 family	185
2918278003	282	97.87	1	282	5	280	5.0e-100	328.8	COG0421	Spermidine synthase	282
2918278004	169	84.67	46	169	11	126	4.6e-36	118.3	COG1586	S-adenosylmethionine decarboxylase or arginine decarboxylase	136
2918278005	565	99.1	5	565	2	553	0.0e+00	747.4	COG3275	Sensor histidine kinase, LytS/YehU family	557
2918278006	249	99.6	11	249	1	247	1.0e-70	233	COG3279	DNA-binding response regulator, LytR/AlgR family	244
2918278007	782	98.68	37	781	10	754	0.0e+00	1040.4	COG1882	Pyruvate-formate lyase	755
2918278008	253	98.36	2	249	2	241	3.3e-76	250.5	COG2071	Gamma-glutamyl-gamma-aminobutyrate hydrolase PuuD (putrescine degradation), contains GATase1-like domain	243
2918278009	168	93.23	39	168	6	129	4.2e-30	99	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918278010	227	77.29	11	227	59	269	8.0e-78	256.3	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
2918278011	252	94.21	1	252	15	258	1.1e-64	213	COG0708	Exonuclease III	261
2918278012	193	84.21	1	189	2	177	1.0e-33	111.3	COG0406	Broad specificity phosphatase PhoE	208
2918278013	390	77.26	4	387	88	403	7.6e-32	105.9	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918278014	326	95.63	140	319	6	180	3.6e-57	187.4	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2918278015	428	80.2	9	410	72	399	8.2e-37	122.3	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918278016	409	96	1	401	10	393	1.5e-127	420	COG4671	Predicted glycosyl transferase	400
2918278017	882	27.36	709	882	424	585	1.7e-78	115.6	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
2918278017	882	69.76	9	456	41	453	1.7e-78	141.6	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
2918278018	151	63.3	9	147	2	139	1.6e-30	100.8	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2918278019	388	94.97	24	388	11	293	5.6e-90	295.8	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2918278020	332	99.69	1	328	1	317	1.2e-89	295.6	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2918278021	605	85.29	6	591	69	561	2.7e-61	202.6	COG0747	ABC-type transport system, periplasmic component	556
2918278022	627	99.64	1	573	2	551	0.0e+00	694.3	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
2918278025	376	94.5	1	375	11	388	9.1e-87	285.7	COG4671	Predicted glycosyl transferase	400
2918278026	272	87.03	12	186	23	183	1.7e-42	139.9	COG3108	Uncharacterized conserved protein YcbK, DUF882 family	185
2918278027	291	97.44	19	290	6	271	5.4e-41	135.1	COG1235	Phosphoribosyl 1,2-cyclic phosphodiesterase	269
2918278029	229	98.71	5	229	1	229	1.1e-63	209.2	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918278031	380	98.47	186	380	3	195	1.6e-68	224.7	COG0807	GTP cyclohydrolase II	193
2918278033	171	66.82	5	165	72	216	3.5e-53	175.1	COG3786	L,D-peptidoglycan transpeptidase YkuD, ErfK/YbiS/YcfS/YnhG family	217
2918278034	236	99.13	13	233	2	228	1.6e-76	251.6	COG0325	Uncharacterized pyridoxal phosphate-containing protein, affects Ilv metabolism, UPF0001 family	228
2918278036	387	71.39	72	378	83	339	4.6e-12	40.5	COG3203	Outer membrane protein (porin)	354
2918278037	407	27.22	5	300	152	249	1.6e-12	4.2	COG3203	Outer membrane protein (porin)	354
2918278037	407	45.56	213	398	133	296	1.6e-12	42	COG3203	Outer membrane protein (porin)	354
2918278039	856	99.88	1	856	2	823	0.0e+00	1030.2	COG0495	Leucyl-tRNA synthetase	814
2918278040	180	96.51	14	179	6	171	2.9e-24	80.5	COG5468	Predicted secreted (periplasmic) protein	172
2918278041	341	92.22	4	339	9	316	5.2e-49	161.8	COG1466	DNA polymerase III, delta subunit	334
2918278042	455	97.57	16	442	11	412	1.3e-114	377.9	COG4222	Uncharacterized conserved protein	391
2918278043	220	50.9	4	218	36	177	1.2e-04	17.3	COG0500	SAM-dependent methyltransferase	257
2918278044	308	98.86	42	300	2	262	1.6e-73	242.3	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
2918278045	261	98.11	4	260	2	260	1.3e-84	278.7	COG1192	Cellulose biosynthesis protein BcsQ	259
2918278046	209	81.86	7	201	11	186	4.3e-48	158	COG0357	16S rRNA G527 N7-methylase RsmG (former glucose-inhibited division protein B)	215
2918278047	622	99.36	1	620	3	622	0.0e+00	881.9	COG0445	tRNA U34 5-carboxymethylaminomethyl modifying enzyme MnmG/GidA	621
2918278048	443	99.34	1	443	4	454	0.0e+00	486.4	COG0486	tRNA U34 5-carboxymethylaminomethyl modifying GTPase MnmE/TrmE	454
2918278049	119	95.31	51	115	2	62	6.3e-23	75.1	COG3411	(2Fe-2S) ferredoxin	64
2918278051	672	98.67	1	672	7	674	0.0e+00	792.4	COG1331	Uncharacterized conserved protein YyaL, SSP411 family, contains thoiredoxin and six-hairpin glycosidase-like domains	667
2918278052	164	67.86	4	147	54	167	8.4e-45	147.5	COG0350	O6-methylguanine-DNA--protein-cysteine methyltransferase	168
2918278053	324	99.4	2	324	2	330	1.1e-97	322	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2918278054	226	80.71	1	226	17	221	1.2e-57	190.4	COG0847	DNA polymerase III, epsilon subunit or related 3'-5' exonuclease	243
2918278055	214	97.51	1	200	2	197	1.2e-52	173.3	COG0237	Dephospho-CoA kinase	201
2918278056	284	95.42	2	283	3	273	5.4e-86	282.7	COG0169	Shikimate 5-dehydrogenase	283
2918278057	202	96.91	5	202	4	191	4.4e-50	164.2	COG0424	Predicted house-cleaning NTP pyrophosphatase, Maf/HAM1 superfamily	193
2918278058	279	97.8	1	270	2	268	4.9e-99	325.8	COG1806	Regulator of PEP synthase PpsR, kinase-PPPase family (combines ADP:protein kinase and phosphorylase activities)	273
2918278059	348	97.17	2	347	7	349	3.8e-113	372.6	COG0407	Uroporphyrinogen-III decarboxylase	352
2918278060	355	98.44	5	330	4	319	7.9e-97	318.8	COG0276	Protoheme ferro-lyase (ferrochelatase)	320
2918278061	143	95.97	1	143	7	149	1.9e-61	201.4	COG1981	Uncharacterized membrane protein	149
2918278062	905	93.06	9	902	51	949	0.0e+00	813.9	COG0474	Magnesium-transporting ATPase (P-type)	917
2918278063	418	98.82	1	418	4	420	0.0e+00	719.2	COG1158	Transcription termination factor Rho	422
2918278064	165	92.36	3	163	9	153	5.0e-53	173.5	COG1952	Preprotein translocase subunit SecB	157
2918278065	186	73.91	1	169	5	123	6.5e-44	144	COG3030	Protein affecting phage T7 exclusion by the F plasmid, UPF0716 family	158
2918278066	217	81.49	1	217	50	278	7.6e-48	158.2	COG4395	Predicted lipid-binding transport protein, Tim44 family	281
2918278067	394	96.57	4	393	8	373	2.2e-102	337.4	COG2821	Membrane-bound lytic murein transglycosylase	373
2918278069	511	86.92	16	399	51	409	6.6e-25	82.1	COG2133	Glucose/arabinose dehydrogenase, beta-propeller fold	399
2918278070	122	76.6	7	122	2	109	4.1e-32	105.6	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
2918278071	112	97.92	12	110	1	94	9.4e-34	110.2	COG0140	Phosphoribosyl-ATP pyrophosphohydrolase	92
2918278072	261	99.22	1	253	1	255	5.9e-118	387.4	COG0107	Imidazole glycerol phosphate synthase subunit HisF	256
2918278073	249	98.34	1	242	2	238	5.0e-92	302.1	COG0106	Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase	241
2918278074	182	68.25	12	162	42	170	1.4e-14	49	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
2918278075	214	99.02	1	214	1	202	3.7e-78	256.7	COG0118	Imidazoleglycerol phosphate synthase glutamine amidotransferase subunit HisH	204
2918278076	207	98.97	7	203	3	195	1.2e-88	290.4	COG0131	Imidazoleglycerol phosphate dehydratase HisB	195
2918278077	476	52.05	170	459	62	251	3.6e-08	27.2	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
2918278078	182	97.75	8	182	2	175	1.5e-83	273.4	COG5405	ATP-dependent protease HslVU (ClpYQ), peptidase subunit	178
2918278079	438	99.55	2	438	3	444	0.0e+00	685.9	COG1220	ATP-dependent protease HslVU (ClpYQ), ATPase subunit	444
2918278080	217	96	1	217	7	222	6.5e-88	288.6	COG2057	Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit	225
2918278081	220	98.18	1	219	3	218	2.6e-82	269.9	COG1788	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit	220
2918278082	513	66.24	75	513	129	389	3.2e-70	231.3	COG0642	Signal transduction histidine kinase	336
2918278083	133	54.62	3	128	2	72	7.6e-16	53.6	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918278084	189	98.37	1	187	2	182	7.4e-44	144.7	COG2840	DNA-nicking endonuclease, Smr domain	184
2918278085	226	98.21	5	224	4	222	8.8e-34	111.5	COG1556	L-lactate utilization protein LutC, contains LUD domain	218
2918278086	473	99.13	2	466	4	459	0.0e+00	535.5	COG1139	L-lactate utilization protein LutB, contains a ferredoxin-type domain	459
2918278087	257	61.35	1	250	154	399	3.0e-64	212.1	COG0247	Fe-S oxidoreductase	388
2918278088	261	93.84	1	261	10	268	2.0e-81	268.1	COG1108	ABC-type Mn2+/Zn2+ transport system, permease component	274
2918278089	235	92.13	1	219	19	252	4.4e-74	243.6	COG1121	ABC-type Mn2+/Zn2+ transport system, ATPase component	254
2918278090	305	95.41	2	305	14	325	1.9e-107	353.2	COG4531	ABC-type Zn2+ transport system, periplasmic component/surface adhesin	318
2918278091	265	98.88	1	265	3	266	3.3e-95	313.2	COG0289	Dihydrodipicolinate reductase	266
2918278092	294	78.79	3	130	22	125	9.3e-21	68	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918278092	294	98.21	122	284	3	167	5.5e-38	125.3	COG0350	O6-methylguanine-DNA--protein-cysteine methyltransferase	168
2918278093	167	93.29	1	158	11	163	1.1e-52	172.7	COG5488	Uncharacterized membrane protein	164
2918278094	214	98.58	1	211	2	209	3.8e-83	272.5	COG0177	Endonuclease III	211
2918278095	572	91.06	102	567	37	423	1.0e-53	176.1	COG0840	Methyl-accepting chemotaxis protein	408
2918278096	288	76.71	147	279	14	125	6.9e-15	49.4	COG1664	Cytoskeletal protein CcmA, bactofilin family	146
2918278097	223	75.6	3	222	53	241	8.8e-25	82.1	COG2981	Uncharacterized protein involved in cysteine biosynthesis	250
2918278098	332	97.78	7	328	1	309	7.7e-72	236.5	COG0524	Sugar or nucleoside kinase, ribokinase family	311
2918278099	305	97.68	8	292	2	254	3.1e-55	181.8	COG0730	Uncharacterized membrane protein YfcA	258
2918278101	169	77.36	17	158	8	130	5.0e-09	31.6	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2918278102	491	50.9	201	484	43	184	2.1e-06	22.6	COG0500	SAM-dependent methyltransferase	257
2918278103	119	77.52	2	117	26	125	7.4e-19	62.4	COG0662	Mannose-6-phosphate isomerase, cupin superfamily	127
2918278104	416	91.39	178	416	10	232	2.6e-46	152.8	COG2114	Adenylate cyclase, class 3	227
2918278105	183	84.95	101	183	6	84	9.0e-31	99.4	COG0694	Fe-S cluster biogenesis protein NfuA, 4Fe-4S-binding domain	93
2918278106	350	63.81	53	292	25	195	7.0e-16	52.7	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
2918278107	183	82.94	1	177	35	209	5.5e-54	177.6	COG2173	D-alanyl-D-alanine dipeptidase	211
2918278108	223	97.74	1	220	1	216	5.4e-44	145.4	COG1214	tRNA A37 threonylcarbamoyladenosine modification protein TsaB	220
2918278109	154	85.19	2	150	23	183	3.8e-28	93.2	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
2918278110	84	92.5	2	84	5	78	1.1e-12	42.4	COG0425	TusA-related sulfurtransferase	78
2918278111	138	89.86	1	138	9	141	4.6e-63	206.3	COG4957	Predicted transcriptional regulator	148
2918278112	273	85.67	6	268	35	285	5.9e-67	220.4	COG3176	Putative hemolysin	292
2918278113	287	86.59	22	267	30	255	1.0e-37	124.3	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
2918278114	462	99.09	1	446	3	439	0.0e+00	514.6	COG0621	tRNA A37 methylthiotransferase MiaB	437
2918278115	349	95.29	4	336	13	336	4.3e-128	421.7	COG1702	Phosphate starvation-inducible protein PhoH, predicted ATPase	348
2918278116	175	96.1	2	160	5	152	9.0e-49	159.6	COG0319	ssRNA-specific RNase YbeY, 16S rRNA maturation enzyme	153
2918278117	305	61.87	21	300	162	432	7.7e-86	283	COG1253	Hemolysin or related protein, contains CBS domains	429
2918278118	542	96.54	14	542	13	514	8.3e-118	388.1	COG0815	Apolipoprotein N-acyltransferase	518
2918278119	121	49.23	1	115	15	78	8.6e-11	37.6	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918278120	389	98.46	2	389	4	386	0.0e+00	559.3	COG0192	S-adenosylmethionine synthetase	388
2918278121	242	85.46	16	241	32	225	2.7e-49	162.4	COG0220	tRNA G46 methylase TrmB	227
2918278122	161	95.45	1	151	7	153	7.5e-50	163.4	COG0779	Ribosome maturation factor RimP	153
2918278123	511	97.99	154	392	2	196	2.7e-85	278.4	COG0195	Transcription antitermination factor NusA, contains S1 and KH domains	190
2918278124	235	89.47	27	120	4	88	2.4e-22	73	COG2740	Predicted RNA-binding protein YlxR, DUF448 family	95
2918278125	910	99.29	405	910	3	559	0.0e+00	550	COG0532	Translation initiation factor IF-2, a GTPase	509
2918278126	186	96.64	1	128	4	118	2.1e-32	106.2	COG0858	Ribosome-binding factor A	118
2918278127	312	98.06	2	312	4	307	5.8e-103	339.2	COG0130	tRNA U55 pseudouridine synthase TruB, may also work on U342 of tmRNA	271
2918278128	89	100	1	89	1	89	4.3e-38	123.9	COG0184	Ribosomal protein S15P/S13E	89
2918278129	707	99.57	1	692	3	693	0.0e+00	1047.9	COG1185	Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase)	692
2918278130	298	98.99	1	298	1	293	1.6e-121	399.8	COG2321	Predicted metalloprotease	295
2918278131	180	82.61	16	169	26	158	5.9e-07	23.8	COG3476	Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)	161
2918278132	344	91.62	1	344	25	363	2.3e-121	399.6	COG1509	L-lysine 2,3-aminomutase (EF-P beta-lysylation pathway)	369
2918278133	245	96.31	2	245	9	269	4.9e-57	187.8	COG0584	Glycerophosphoryl diester phosphodiesterase	257
2918278134	465	89.86	2	378	7	316	4.8e-19	61.3	COG2070	NAD(P)H-dependent flavin oxidoreductase YrpB, nitropropane dioxygenase family	336
2918278135	144	88.97	5	144	7	135	1.8e-26	87.4	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
2918278136	137	77.4	4	137	3	139	1.3e-43	144.1	COG1592	Rubrerythrin	166
2918278137	451	98.75	28	448	3	398	3.8e-43	142.3	COG0247	Fe-S oxidoreductase	388
2918278139	180	91.23	10	180	15	170	3.0e-58	190.8	COG3807	SH3-like domain	171
2918278140	329	99.08	5	326	2	325	9.4e-115	377.5	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
2918278141	185	89	1	184	3	180	8.2e-21	68.9	COG4636	Endonuclease, Uma2 family (restriction endonuclease fold)	200
2918278142	899	8.99	640	703	191	247	0.0e+00	3.8	COG1042	Acyl-CoA synthetase (NDP forming)	598
2918278142	899	83.95	738	888	18	153	3.8e-10	32.1	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2918278142	899	99.84	3	632	2	634	0.0e+00	672.9	COG1042	Acyl-CoA synthetase (NDP forming)	598
2918278143	316	98.73	1	314	1	311	9.8e-90	295.5	COG0039	Malate/lactate dehydrogenase	313
2918278144	169	95.6	1	168	2	175	5.4e-58	190.4	COG2110	O-acetyl-ADP-ribose deacetylase (regulator of RNase III), contains Macro domain	179
2918278145	185	98.84	1	175	1	170	6.4e-68	222.5	COG0221	Inorganic pyrophosphatase	171
2918278146	570	92.51	1	570	39	569	0.0e+00	436.6	COG4166	ABC-type oligopeptide transport system, periplasmic component	562
2918278147	227	15.64	33	75	2	29	8.8e-08	3.5	COG1102	Cytidylate kinase	179
2918278147	227	51.4	111	227	77	168	8.8e-08	20.7	COG1102	Cytidylate kinase	179
2918278148	512	90.62	9	512	39	502	0.0e+00	524.2	COG0661	Predicted unusual protein kinase regulating ubiquinone biosynthesis, AarF/ABC1/UbiB family	517
2918278149	263	98.33	27	263	4	238	9.3e-81	265.1	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
2918278153	280	99.64	1	280	1	273	1.9e-95	314.4	COG0266	Formamidopyrimidine-DNA glycosylase	273
2918278155	258	99.25	1	255	3	265	5.3e-89	292.8	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918278156	86	96.59	1	86	1	85	3.9e-32	105.4	COG0268	Ribosomal protein S20	88
2918278157	494	99.77	11	490	1	432	0.0e+00	531.4	COG0593	Chromosomal replication initiation ATPase DnaA	408
2918278158	310	69.66	1	297	131	433	7.7e-75	246.7	COG3706	Two-component response regulator, PleD family, consists of two REC domains and a diguanylate cyclase (GGDEF) domain	435
2918278159	389	87.04	16	373	3	331	7.9e-54	177.6	COG0687	Spermidine/putrescine-binding periplasmic protein	363
2918278160	387	98.02	2	354	6	351	3.1e-115	379.8	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
2918278161	592	92.13	1	119	10	126	3.2e-25	82.8	COG2372	Copper-binding protein CopC (methionine-rich)	127
2918278161	592	98.27	136	419	6	289	2.3e-39	129.9	COG1276	Putative copper export protein	289
2918278162	175	94.38	4	175	7	174	9.4e-56	183	COG4549	Uncharacterized protein YcnI	178
2918278164	294	92.71	6	291	13	279	6.9e-79	259.7	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
2918278165	270	97	1	266	7	265	5.7e-71	233.5	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
2918278166	80	35.05	2	80	120	187	1.3e-03	12.8	COG1094	rRNA processing protein Krr1/Pno1, contains KH domain	194
2918278167	160	90.65	32	160	11	136	3.1e-29	96.2	COG0824	Acyl-CoA thioesterase FadM	137
2918278168	462	99.59	7	462	1	482	9.8e-91	299.7	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
2918278169	440	99.08	16	434	5	436	3.7e-81	267.9	COG2265	tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family	432
2918278170	402	99.24	14	402	3	392	2.0e-104	344.3	COG1092	23S rRNA G2069 N7-methylase RlmK or C1962 C5-methylase RlmI	393
2918278172	498	97.31	13	494	7	477	0.0e+00	771.4	COG3278	Cbb3-type cytochrome oxidase, subunit 1	482
2918278173	246	98.25	5	241	3	226	4.0e-109	357.9	COG2993	Cbb3-type cytochrome oxidase, cytochrome c subunit	227
2918278174	53	76.67	1	52	8	53	7.5e-13	43.3	COG4736	Cbb3-type cytochrome oxidase, subunit 3	60
2918278175	295	53.66	198	295	56	143	1.0e-45	63.8	COG2010	Cytochrome c, mono- and diheme variants	150
2918278175	295	85.37	51	202	1	140	1.0e-45	92.6	COG2010	Cytochrome c, mono- and diheme variants	150
2918278176	507	99.24	45	487	2	395	8.6e-116	381.6	COG0348	Polyferredoxin	386
2918278177	172	94.58	7	172	5	161	4.5e-28	92.6	COG5456	Nitrogen fixation protein FixH	166
2918278178	821	99.18	80	787	3	727	0.0e+00	691	COG2217	Cation transport ATPase	713
2918278179	66	94.83	1	59	1	55	7.5e-25	81.3	COG3197	Uncharacterized protein, possibly involved in nitrogen fixation	58
2918278180	220	94.04	2	210	12	216	4.2e-47	155.1	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2918278181	495	93.6	2	492	21	561	6.4e-104	343.3	COG0747	ABC-type transport system, periplasmic component	556
2918278182	315	99.06	1	315	2	316	4.2e-108	356.2	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2918278183	275	90.94	1	272	26	296	4.9e-84	276.5	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2918278185	166	72.07	3	152	47	175	5.4e-25	82.3	COG0503	Adenine/guanine phosphoribosyltransferase or related PRPP-binding protein	179
2918278190	170	97.01	1	163	5	166	4.7e-43	141.7	COG3685	Ferritin-like metal-binding protein YciE	167
2918278192	63	70.27	5	63	3	54	4.4e-18	60	COG3313	Predicted Fe-S protein YdhL, DUF1289 family	74
2918278193	177	34.83	14	93	29	90	2.7e-19	31.1	COG1633	Rubrerythrin	176
2918278193	177	38.2	84	171	17	84	2.7e-19	36.9	COG1633	Rubrerythrin	176
2918278194	280	69.9	10	235	5	213	3.3e-75	247.6	COG1013	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, beta subunit	294
2918278195	573	86.65	200	566	6	336	1.2e-86	285.6	COG0674	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, alpha subunit	365
2918278195	573	94.61	4	190	4	196	4.6e-27	88.9	COG1014	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, gamma subunit	203
2918278196	226	78.2	15	226	40	265	1.4e-63	209.5	COG2041	Periplasmic DMSO/TMAO reductase YedYZ, molybdopterin-dependent catalytic subunit	271
2918278197	780	28.36	242	507	37	133	3.8e-54	7	COG0668	Small-conductance mechanosensitive channel	316
2918278197	780	82.75	489	779	43	325	3.8e-54	176.9	COG0668	Small-conductance mechanosensitive channel	316
2918278198	155	85.82	1	138	4	124	1.9e-43	141.7	COG5478	Low affinity Fe/Cu permease	141
2918278199	529	39.19	19	225	11	155	6.5e-77	23.1	COG3437	Response regulator c-di-GMP phosphodiesterase, RpfG family, contains REC and HD-GYP domains	360
2918278199	529	50	294	524	175	359	6.5e-77	228.6	COG3437	Response regulator c-di-GMP phosphodiesterase, RpfG family, contains REC and HD-GYP domains	360
2918278200	242	91.13	14	218	8	192	2.0e-25	84.1	COG0461	Orotate phosphoribosyltransferase	201
2918278201	602	86.56	13	297	42	305	1.7e-53	176.1	COG5309	Exo-beta-1,3-glucanase,  GH17 family	305
2918278202	257	98.88	1	254	4	268	1.7e-60	199.3	COG1018	Ferredoxin-NADP reductase	266
2918278203	482	78.26	1	95	4	57	1.2e-08	28.2	COG1476	DNA-binding transcriptional regulator, XRE-family HTH domain	68
2918278203	482	99.4	143	475	2	331	0.0e+00	439.6	COG3800	Predicted transcriptional regulator	332
2918278204	425	37.5	243	424	296	472	0.0e+00	257.7	COG2224	Isocitrate lyase	433
2918278204	425	52.75	2	246	12	260	0.0e+00	340.9	COG2224	Isocitrate lyase	433
2918278205	187	95.41	6	182	3	189	5.0e-22	73.3	COG0693	Putative intracellular protease/amidase	188
2918278206	633	89.09	233	625	40	390	1.8e-67	223.4	COG0642	Signal transduction histidine kinase	336
2918278207	549	43.12	1	228	4	241	2.7e-87	107.6	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
2918278207	549	47.28	217	492	288	548	2.7e-87	174.6	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
2918278208	253	70.13	14	252	83	291	1.4e-34	113.9	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2918278209	257	71.38	41	257	90	316	1.1e-26	84.8	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2918278210	750	75.05	15	494	63	426	2.0e-50	166.2	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
2918278210	750	91.07	522	749	6	209	4.6e-36	118.6	COG0398	Uncharacterized membrane protein YdjX, TVP38/TMEM64 family, SNARE-associated domain	223
2918278211	270	97.28	36	270	5	254	1.1e-51	170.2	COG3568	Metal-dependent hydrolase, endonuclease/exonuclease/phosphatase family	259
2918278212	406	98.07	1	406	2	408	0.0e+00	614.8	COG4553	Poly-beta-hydroxyalkanoate depolymerase	415
2918278213	362	97.36	14	360	3	334	2.2e-86	284.1	COG1612	Heme A synthase	323
2918278214	1162	26.2	227	408	35	154	6.8e-37	30.6	COG0493	NADPH-dependent glutamate synthase beta chain or related oxidoreductase	457
2918278214	1162	62.45	443	822	157	442	6.8e-37	85.8	COG0493	NADPH-dependent glutamate synthase beta chain or related oxidoreductase	457
2918278214	1162	78.21	835	1067	13	213	5.8e-21	68.1	COG0543	NAD(P)H-flavin reductase	252
2918278215	87	91.11	1	87	6	87	2.6e-36	118.7	COG5425	Usg protein (tryptophan operon, function unknown)	90
2918278216	96	98.96	1	96	1	95	3.1e-43	140.6	COG0234	Co-chaperonin GroES (HSP10)	96
2918278217	547	99.64	1	537	1	548	0.0e+00	636.5	COG0459	Chaperonin GroEL (HSP60 family)	524
2918278218	378	71.26	9	378	9	365	0.0e+00	561.9	COG0753	Catalase	496
2918278220	338	87.12	9	325	40	357	8.6e-111	364.9	COG1858	Cytochrome c peroxidase	364
2918278221	385	19.47	314	364	126	162	1.2e-80	4.2	COG3005	Tetraheme cytochrome c subunit of nitrate or TMAO reductase	190
2918278221	385	89.47	2	188	17	186	1.2e-80	260.1	COG3005	Tetraheme cytochrome c subunit of nitrate or TMAO reductase	190
2918278223	411	98.28	9	408	5	404	3.6e-115	379.5	COG2081	Predicted flavoprotein YhiN	408
2918278224	717	93.69	40	710	11	678	0.0e+00	675.5	COG0744	Membrane carboxypeptidase (penicillin-binding protein)	661
2918278226	335	68.09	3	334	142	459	1.2e-107	355.2	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2918278228	223	98.23	1	222	1	222	8.3e-46	151.1	COG1842	Phage shock protein A	225
2918278230	137	89.86	15	82	4	65	1.3e-20	66.2	COG1983	Phage shock protein PspC (stress-responsive transcriptional regulator)	70
2918278231	40	5.45	2	37	447	477	5.5e-04	13.4	COG0804	Urease alpha subunit	568
2918278234	522	40.69	12	224	117	293	2.8e-73	39.6	COG3706	Two-component response regulator, PleD family, consists of two REC domains and a diguanylate cyclase (GGDEF) domain	435
2918278234	522	43.22	310	521	246	433	2.8e-73	201.7	COG3706	Two-component response regulator, PleD family, consists of two REC domains and a diguanylate cyclase (GGDEF) domain	435
2918278235	157	86.58	4	157	16	144	5.3e-51	166.9	COG3019	Uncharacterized conserved protein	149
2918278236	271	43.24	2	132	145	256	5.5e-28	35.4	COG0730	Uncharacterized membrane protein YfcA	258
2918278236	271	45.17	142	271	7	123	5.5e-28	63.5	COG0730	Uncharacterized membrane protein YfcA	258
2918278237	295	75.71	1	57	12	64	3.5e-03	11.3	COG3311	Predicted DNA-binding transcriptional regulator AlpA	70
2918278237	295	90.13	70	293	2	202	5.8e-40	131.4	COG1910	Periplasmic molybdate-binding protein/domain	223
2918278239	234	65.95	12	201	58	210	1.3e-15	52.6	COG0671	Membrane-associated phospholipid phosphatase	232
2918278241	340	98.83	2	340	2	338	0.0e+00	430.6	COG1064	D-arabinose 1-dehydrogenase, Zn-dependent alcohol dehydrogenase family	339
2918278243	487	96.73	28	464	4	387	8.8e-105	345.2	COG0348	Polyferredoxin	386
2918278246	335	97.1	1	335	5	339	6.7e-105	345.9	COG1294	Cytochrome bd-type quinol oxidase, subunit 2	346
2918278247	474	96.93	4	452	2	443	0.0e+00	521.7	COG1271	Cytochrome bd-type quinol oxidase, subunit 1	457
2918278248	316	97.48	4	300	2	272	8.3e-39	127.7	COG0388	Predicted amidohydrolase	274
2918278249	226	96.21	13	222	4	206	1.1e-56	186	COG0800	2-keto-3-deoxy-6-phosphogluconate aldolase	211
2918278250	482	98.68	28	476	3	452	1.3e-99	328.7	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
2918278252	128	94.44	1	122	7	125	4.8e-46	150.3	COG5349	Uncharacterized conserved protein, DUF983 family	126
2918278253	407	99.74	1	395	2	390	0.0e+00	466.4	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
2918278254	338	92.24	1	337	25	357	3.4e-89	293.8	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
2918278255	386	98.65	9	385	3	367	3.9e-108	356.2	COG1932	Phosphoserine aminotransferase	365
2918278256	125	93.75	1	124	7	126	2.9e-28	92.8	COG1380	Putative effector of murein hydrolase LrgA, UPF0299 family	128
2918278257	237	97.83	9	237	4	228	1.1e-68	225.6	COG1346	Putative effector of murein hydrolase	230
2918278259	116	86.11	3	114	5	97	1.5e-17	58.5	COG5569	Periplasmic Cu and Ag efflux protein CusF	108
2918278260	1067	99.51	1	1039	1	1025	0.0e+00	1359.8	COG3696	Cu/Ag efflux pump CusA	1027
2918278261	425	18.72	79	200	34	106	1.6e-27	10.3	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918278261	425	53.59	169	415	166	374	1.6e-27	85.5	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918278262	423	93.91	1	423	16	447	3.3e-35	116.5	COG1538	Outer membrane protein TolC	457
2918278266	259	98.28	24	256	2	229	5.7e-81	265.9	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918278267	446	80.2	106	445	71	386	3.0e-51	169.5	COG0642	Signal transduction histidine kinase	336
2918278268	251	70.09	11	251	97	321	7.0e-72	237.2	COG3667	Uncharacterized protein involved in copper resistance	321
2918278269	582	99.59	10	577	1	482	2.7e-120	397.5	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
2918278270	190	91.14	8	190	14	157	3.1e-39	128.9	COG4454	Uncharacterized copper-binding protein, cupredoxin-like subfamily	158
2918278277	289	11.21	226	288	40	77	5.5e-14	14.4	COG4447	Uncharacterized protein related to plant photosystem II stability/assembly factor	339
2918278277	289	16.52	160	244	257	312	5.5e-14	9.4	COG4447	Uncharacterized protein related to plant photosystem II stability/assembly factor	339
2918278277	289	45.13	1	163	9	161	5.5e-14	21.4	COG4447	Uncharacterized protein related to plant photosystem II stability/assembly factor	339
2918278280	758	87.28	31	758	89	726	0.0e+00	826.1	COG2217	Cation transport ATPase	713
2918278281	320	91.62	25	320	9	325	3.2e-93	300.3	COG1171	Threonine dehydratase	347
2918278282	290	84.24	1	289	16	293	1.1e-64	213.3	COG0714	MoxR-like ATPase	329
2918278283	125	85.71	2	101	14	103	2.5e-26	86.7	COG4323	Uncharacterized protein	105
2918278284	138	88.19	2	136	2	128	4.3e-26	86.2	COG2703	Hemerythrin	144
2918278285	889	99.09	1	887	7	880	0.0e+00	1139.3	COG0013	Alanyl-tRNA synthetase	879
2918278287	346	97.94	1	280	6	290	7.4e-129	423.4	COG0468	RecA/RadA recombinase	279
2918278289	846	66.5	280	707	129	390	8.8e-59	193.6	COG0642	Signal transduction histidine kinase	336
2918278290	358	96.42	2	358	3	352	2.6e-120	396.4	COG1377	Flagellar biosynthesis protein FlhB	363
2918278291	256	95.74	1	254	1	247	3.9e-55	181.6	COG1684	Flagellar biosynthesis protein FliR	258
2918278292	100	94.38	1	89	1	84	2.9e-24	79.7	COG1987	Flagellar biosynthesis protein FliQ	89
2918278293	99	77.36	1	99	25	106	1.1e-22	75.3	COG1677	Flagellar hook-basal body complex protein FliE	105
2918278294	136	100	1	135	1	138	4.5e-48	157.6	COG1558	Flagellar basal body rod protein FlgC	137
2918278295	135	94.81	5	133	7	134	4.4e-33	109	COG1815	Flagellar basal body rod protein FlgB	133
2918278296	186	92.86	1	166	5	147	1.3e-52	172.2	COG2847	Copper(I)-binding protein	151
2918278297	108	88.04	7	99	9	89	3.9e-25	82.6	COG2257	Type III secretion system substrate exporter, FlhB-like	92
2918278299	104	42.86	3	78	25	84	1.0e-08	29.6	COG3190	Flagellar biogenesis protein FliO	137
2918278300	253	87.95	5	251	30	248	1.9e-98	323.5	COG1338	Flagellar biosynthetic protein FliP	248
2918278301	642	98.09	2	642	12	626	0.0e+00	874.4	COG3158	K+ transporter	627
2918278303	227	85.93	7	218	8	239	7.3e-19	58.4	COG1360	Flagellar motor protein MotB	244
2918278305	237	32.26	40	126	16	85	1.1e-14	15.1	COG3143	Chemotaxis regulator CheZ, phosphatase of CheY~P	217
2918278305	237	41.47	116	237	125	214	1.1e-14	32.6	COG3143	Chemotaxis regulator CheZ, phosphatase of CheY~P	217
2918278306	302	58.97	115	301	72	186	5.5e-22	73.2	COG3334	Flagellar motility protein MotE, a chaperone for MotC folding	192
2918278308	358	95.8	36	357	4	322	1.4e-61	202.9	COG1868	Flagellar motor switch protein FliM	332
2918278309	176	93.71	11	176	11	159	3.2e-18	60.5	COG1580	Flagellar basal body-associated protein FliL	159
2918278310	240	99.25	1	237	1	263	2.8e-66	216.9	COG4786	Flagellar basal body rod protein FlgG	265
2918278311	261	98.87	1	261	2	263	6.0e-96	315.6	COG4786	Flagellar basal body rod protein FlgG	265
2918278312	252	56.82	69	246	95	219	3.3e-26	86.9	COG1261	Flagella basal body P-ring formation protein FlgA	220
2918278313	257	93.51	8	254	15	230	5.3e-62	203.9	COG2063	Flagellar basal body L-ring protein FlgH	230
2918278326	279	49.38	66	255	52	131	5.1e-03	11.2	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2918278327	197	59.68	5	185	2	152	4.3e-30	99.9	COG3926	Lysozyme family protein	252
2918278349	487	96.2	171	250	2	77	7.8e-34	105.7	COG5565	Bacteriophage terminase large (ATPase) subunit and inactivated derivatives	79
2918278350	159	43.58	6	132	6	83	1.2e-14	49.1	COG3728	Phage terminase, small subunit	179
2918278351	70	50.72	1	51	5	39	1.4e-05	19.3	COG1476	DNA-binding transcriptional regulator, XRE-family HTH domain	68
2918278352	78	53.85	8	61	26	60	5.8e-03	11.3	COG5509	Uncharacterized small protein, DUF1192 family	65
2918278363	355	80.6	49	354	58	327	6.4e-22	73.1	COG0582	Integrase	309
2918278365	139	98.33	19	138	1	118	6.6e-40	131	COG1734	RNA polymerase-binding transcription factor DksA	120
2918278367	382	98.36	16	382	7	365	0.0e+00	461.7	COG1706	Flagellar basal body P-ring protein FlgI	365
2918278368	128	46.78	21	128	25	104	3.3e-17	58	COG3951	Rod binding protein domain	166
2918278370	594	76.26	3	568	47	380	1.5e-02	4.5	COG3144	Flagellar hook-length control protein FliK	417
2918278371	253	93.72	21	252	4	212	1.2e-39	130.7	COG1843	Flagellar hook assembly protein FlgD	222
2918278373	196	91.87	1	195	9	200	9.5e-25	83.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918278374	152	90.57	1	147	15	158	5.7e-38	124.3	COG2030	Acyl dehydratase	159
2918278378	508	55.2	5	303	34	187	3.2e-10	34.4	COG0500	SAM-dependent methyltransferase	257
2918278379	629	97.15	3	608	5	618	0.0e+00	543.1	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
2918278380	170	87.43	12	169	13	158	4.8e-13	44	COG2891	Cell shape-determining protein MreD	167
2918278381	289	92.66	17	286	6	270	4.1e-56	184.6	COG1792	Cell shape-determining protein MreC	284
2918278382	346	97.95	4	345	4	337	0.0e+00	494.6	COG1077	Actin-like ATPase involved in cell morphogenesis	342
2918278383	178	96.45	1	170	4	166	6.3e-63	206.4	COG2862	Uncharacterized membrane protein YqhA	169
2918278384	234	91.84	2	232	9	233	1.8e-50	166.2	COG0704	Phosphate uptake regulator	240
2918278385	339	98.82	1	337	3	336	0.0e+00	537.1	COG0059	Ketol-acid reductoisomerase	338
2918278386	168	96.91	4	168	3	159	9.1e-60	195.8	COG0440	Acetolactate synthase, small subunit	163
2918278387	587	99.46	5	570	2	553	0.0e+00	723.7	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
2918278388	404	83.99	9	404	70	452	0.0e+00	439	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
2918278389	326	91.23	8	319	3	283	1.9e-89	294.3	COG0324	tRNA A37 N6-isopentenylltransferase MiaA	308
2918278390	159	77.85	3	159	34	156	1.0e-10	36.6	COG4454	Uncharacterized copper-binding protein, cupredoxin-like subfamily	158
2918278391	298	98.58	79	289	3	211	7.3e-67	219.4	COG0560	Phosphoserine phosphatase	212
2918278392	518	25.21	410	518	267	358	0.0e+00	35.8	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
2918278392	518	91.51	20	398	26	359	0.0e+00	416.3	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
2918278393	62	98.39	1	61	1	61	9.2e-23	75	COG3242	Uncharacterized conserved protein YjeT, DUF2065 family	62
2918278394	314	97.34	1	289	4	296	1.4e-68	226.1	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
2918278395	394	96.01	62	374	7	295	3.2e-64	211.6	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
2918278396	383	92.66	38	337	21	285	5.8e-100	328.6	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
2918278397	1010	66.75	574	874	127	389	1.5e-62	207.2	COG0642	Signal transduction histidine kinase	336
2918278397	1010	84.52	305	398	8	78	1.9e-03	11.5	COG2770	HAMP domain	83
2918278398	592	88.34	379	590	19	215	1.6e-30	101.4	COG1226	Voltage-gated potassium channel Kch	212
2918278398	592	95.75	1	394	6	388	2.4e-95	314.1	COG0475	Kef-type K+ transport system, membrane component KefB	397
2918278399	265	100	1	264	1	263	9.4e-117	383.5	COG1101	ABC-type uncharacterized transport system, ATPase component	263
2918278400	295	98.29	1	295	1	288	3.7e-123	405.3	COG4120	ABC-type uncharacterized transport system, permease component	293
2918278401	321	97.52	1	320	8	321	5.7e-126	414.5	COG2984	ABC-type uncharacterized transport system, periplasmic component	322
2918278403	125	90.48	1	124	8	121	1.0e-40	133.2	COG5349	Uncharacterized conserved protein, DUF983 family	126
2918278404	631	89.1	32	619	67	622	2.9e-110	364	COG3914	Predicted O-linked N-acetylglucosamine transferase, SPINDLY family	620
2918278405	312	98.55	23	301	4	275	2.3e-71	235.2	COG1351	Thymidylate synthase ThyX	273
2918278407	173	100	1	173	1	157	9.1e-55	179.3	COG3814	Uncharacterized protein	157
2918278408	122	91.74	6	121	7	117	2.5e-27	89.7	COG3070	Transcriptional regulator of competence genes, TfoX/Sxy family	121
2918278409	235	79.48	6	204	31	212	6.9e-37	121.6	COG5590	Ubiquinone biosynthesis protein COQ9	229
2918278410	180	94.08	1	170	1	159	3.6e-54	177.4	COG0242	Peptide deformylase	168
2918278411	67	98.51	1	65	2	67	2.8e-25	82.9	COG0828	Ribosomal protein S21	67
2918278412	276	96.64	9	274	9	267	7.5e-112	367.6	COG0413	Ketopantoate hydroxymethyltransferase	268
2918278413	310	95.02	4	298	8	293	2.4e-46	152.9	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918278414	95	100	1	95	1	96	1.0e-36	119.9	COG5470	Uncharacterized conserved protein, DUF1330 family	96
2918278415	464	99.36	1	462	4	470	0.0e+00	722.9	COG1282	NAD/NADP transhydrogenase beta subunit	463
2918278416	139	28.93	3	139	98	202	2.4e-24	81.1	COG3288	NAD/NADP transhydrogenase alpha subunit	356
2918278417	385	100	2	374	1	363	0.0e+00	488.8	COG3288	NAD/NADP transhydrogenase alpha subunit	356
2918278418	82	91.76	1	81	7	84	5.2e-38	123.4	COG3750	Uncharacterized conserved protein, UPF0335 family	85
2918278419	734	93.58	22	518	24	460	5.3e-110	363.2	COG0147	Anthranilate/para-aminobenzoate synthases component I	462
2918278419	734	97.38	532	723	2	187	2.7e-57	187.7	COG0512	Anthranilate/para-aminobenzoate synthase component II	191
2918278420	203	66.56	8	202	20	218	1.1e-33	111.4	COG1230	Co/Zn/Cd efflux system component	296
2918278421	145	93.25	1	124	10	161	7.1e-27	89.3	COG0517	CBS domain	117
2918278423	331	95.49	4	135	3	129	5.3e-24	78.6	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918278424	1164	95.59	713	924	4	198	2.3e-30	99.8	COG1014	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, gamma subunit	203
2918278424	1164	99.07	16	697	2	639	0.0e+00	623.6	COG4231	TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit	640
2918278425	306	99.22	1	267	1	255	1.8e-53	176.4	COG5662	Transmembrane transcriptional regulator (anti-sigma factor RsiW)	256
2918278426	170	88.71	1	165	17	181	2.0e-49	162.4	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918278427	101	27.4	14	93	20	76	1.1e-03	13.1	COG3404	Formiminotetrahydrofolate cyclodeaminase	208
2918278428	641	99.28	50	614	1	548	0.0e+00	680.7	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
2918278429	201	88.52	1	200	10	194	1.7e-20	69.3	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918278431	607	97.66	19	607	11	595	0.0e+00	595.3	COG1164	Oligoendopeptidase F	598
2918278432	133	90.28	5	133	3	132	4.9e-24	79.6	COG2703	Hemerythrin	144
2918278433	185	92.93	5	185	2	172	1.9e-52	172.4	COG0431	NAD(P)H-dependent FMN reductase	184
2918278434	473	95.1	36	471	16	461	3.9e-49	160.9	COG0277	FAD/FMN-containing dehydrogenase	459
2918278435	448	80.08	6	443	25	434	1.2e-90	299.3	COG0661	Predicted unusual protein kinase regulating ubiquinone biosynthesis, AarF/ABC1/UbiB family	517
2918278436	340	99.14	1	340	1	346	0.0e+00	458.5	COG0809	S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase)	348
2918278437	394	97.04	11	380	1	361	0.0e+00	543.6	COG0343	Queuine/archaeosine tRNA-ribosyltransferase	372
2918278438	154	87.25	3	147	17	146	1.9e-52	171.5	COG0780	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF, C-terminal domain, T-fold superfamily	149
2918278439	361	99.41	13	350	3	341	0.0e+00	440.4	COG1600	Epoxyqueuosine reductase  QueG (queuosine biosynthesis)	337
2918278440	551	96.65	17	551	13	561	1.2e-113	374.9	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2918278441	392	88.17	30	392	45	387	8.9e-45	147.5	COG4552	Predicted acetyltransferase	389
2918278442	800	81.18	413	795	79	423	1.8e-62	206.8	COG0840	Methyl-accepting chemotaxis protein	408
2918278443	411	91.14	2	409	26	416	6.2e-16	52.8	COG3307	O-antigen ligase	424
2918278444	309	83.82	4	295	2	286	2.9e-46	153	COG0859	ADP-heptose:LPS heptosyltransferase	334
2918278445	337	89.81	17	332	19	309	1.4e-15	51.6	COG0392	Uncharacterized membrane protein YbhN, UPF0104 family	322
2918278446	496	61.09	22	195	10	155	5.6e-12	39.4	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
2918278447	160	86.45	8	159	16	149	1.4e-32	107.1	COG2606	Cys-tRNA(Pro) deacylase, prolyl-tRNA editing enzyme YbaK/EbsC	155
2918278448	272	98.13	5	272	4	266	8.1e-80	262.7	COG0345	Pyrroline-5-carboxylate reductase	266
2918278449	167	94.58	1	167	10	166	9.5e-50	163.4	COG5465	Uncharacterized protein	166
2918278450	132	75.73	1	101	13	90	3.1e-22	73.4	COG2960	Uncharacterized conserved protein YqiC, BMFP domain	103
2918278451	1126	12.41	429	781	450	533	1.0e-52	2.6	COG2982	Uncharacterized protein involved in outer membrane biogenesis	648
2918278451	1126	45.79	636	1102	314	623	1.0e-52	42.3	COG2982	Uncharacterized protein involved in outer membrane biogenesis	648
2918278451	1126	54.21	1	358	7	373	1.0e-52	133.5	COG2982	Uncharacterized protein involved in outer membrane biogenesis	648
2918278453	273	92.04	4	273	17	282	9.0e-40	131.4	COG5473	Uncharacterized membrane protein	290
2918278454	62	81.54	1	61	11	63	4.2e-13	44.3	COG5509	Uncharacterized small protein, DUF1192 family	65
2918278455	335	100	9	333	1	331	5.3e-106	349.4	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2918278456	328	97.81	9	328	7	318	1.5e-92	304.7	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918278457	206	74.78	1	204	4	175	3.9e-84	276.5	COG3820	Uncharacterized protein	230
2918278458	197	97.38	4	191	4	189	6.1e-81	265.2	COG0163	3-polyprenyl-4-hydroxybenzoate decarboxylase	191
2918278459	229	97.6	7	229	2	204	9.5e-52	169.6	COG0288	Carbonic anhydrase	207
2918278462	359	89.3	3	172	13	179	1.0e-38	68.2	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
2918278462	359	89.3	181	359	13	179	1.0e-38	64.4	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
2918278463	164	88.89	8	148	17	160	2.3e-16	54.8	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2918278465	140	87.5	7	140	19	144	6.0e-14	46.6	COG3793	Tellurite resistance protein	144
2918278467	466	99.35	5	466	3	461	0.0e+00	773	COG0114	Fumarate hydratase class II	462
2918278468	67	64.71	1	67	15	80	4.3e-21	69.3	COG4321	Predicted DNA-binding protein, contains Ribbon-helix-helix (RHH) domain	102
2918278469	240	96.58	4	235	3	228	8.4e-71	232.7	COG3821	Uncharacterized membrane protein	234
2918278471	575	91.83	312	566	7	242	6.9e-62	202.9	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
2918278472	365	93.09	14	364	2	351	0.0e+00	436.4	COG0026	Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)	375
2918278473	169	94.51	4	168	4	158	3.0e-70	229.6	COG0041	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase	162
2918278474	60	86.57	1	60	10	67	6.9e-21	69.1	COG5481	Uncharacterized protein	67
2918278475	361	90.2	3	357	3	324	2.7e-98	323.7	COG0205	6-phosphofructokinase	347
2918278476	154	71.34	2	144	11	127	1.4e-26	87.7	COG5589	Uncharacterized protein	164
2918278477	352	49.88	22	345	204	407	1.0e-24	81.2	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918278478	273	86.99	10	253	8	221	3.2e-27	90.3	COG2120	N-acetylglucosaminyl deacetylase, LmbE family	237
2918278479	305	76.4	1	303	56	382	6.0e-59	194.7	COG3664	Beta-xylosidase	428
2918278480	251	47.67	6	245	52	184	3.2e-10	35.3	COG0500	SAM-dependent methyltransferase	257
2918278481	246	81.79	1	245	1	238	4.2e-20	66.4	COG1209	dTDP-glucose pyrophosphorylase	286
2918278482	358	96.25	3	354	2	360	2.6e-56	185.7	COG4641	Spore maturation protein CgeB	373
2918278483	204	91.39	1	200	2	192	5.8e-48	158	COG0406	Broad specificity phosphatase PhoE	208
2918278484	366	98.94	6	363	4	376	0.0e+00	475.4	COG1260	Myo-inositol-1-phosphate synthase	362
2918278485	537	94.77	6	537	4	510	1.5e-119	394.8	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
2918278486	435	98.15	16	432	8	379	5.2e-95	313	COG1454	Alcohol dehydrogenase, class IV	377
2918278487	241	93.61	2	241	2	250	4.4e-64	211.3	COG1801	Uncharacterized conserved protein YecE, DUF72 family	263
2918278489	435	92.51	6	357	24	344	4.4e-113	372.5	COG2951	Membrane-bound lytic murein transglycosylase B	343
2918278490	139	100	1	138	1	137	3.3e-47	154.5	COG0432	Thiamin phosphate synthase YjbQ, UPF0047 family	137
2918278491	150	98.63	1	147	1	144	3.4e-34	112.5	COG3427	Carbon monoxide dehydrogenase subunit G	146
2918278493	799	77.99	3	327	60	346	2.5e-19	64.2	COG0457	Tetratricopeptide (TPR) repeat	291
2918278494	257	63.03	12	256	45	269	3.1e-47	156	COG2273	Beta-glucanase, GH16 family	355
2918278496	136	55.92	13	136	2	119	6.6e-27	89.1	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918278497	1302	48.71	1034	1181	3	115	3.4e-30	77.9	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918278497	1302	53.02	885	1029	2	124	3.4e-30	19.5	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918278497	1302	68	1186	1299	5	89	3.8e-14	46.4	COG2198	HPt (histidine-containing phosphotransfer) domain	122
2918278497	1302	79.44	526	873	76	388	6.3e-81	267.7	COG0642	Signal transduction histidine kinase	336
2918278500	374	98.88	10	373	2	354	5.4e-130	428.4	COG0482	tRNA U34 2-thiouridine synthase MnmA/TrmU, contains the PP-loop ATPase domain	356
2918278501	109	97.09	1	104	1	100	1.6e-25	83.6	COG0633	Ferredoxin	102
2918278502	214	63.79	52	204	2	112	2.8e-08	28.1	COG1076	DnaJ-domain-containing proteins 1	174
2918278503	370	97.67	2	369	2	378	2.3e-120	396.6	COG1104	Cysteine sulfinate desulfinase/cysteine desulfurase or related enzyme	386
2918278504	160	89.33	1	147	1	134	1.7e-48	159.1	COG1959	DNA-binding transcriptional regulator, IscR family	150
2918278505	251	87.76	1	185	7	178	2.2e-78	256.7	COG1045	Serine acetyltransferase	194
2918278506	221	97.14	1	212	4	207	3.8e-83	272.5	COG2945	Alpha/beta superfamily hydrolase	210
2918278508	354	98.4	1	354	5	372	7.7e-115	378.9	COG2377	1,6-Anhydro-N-acetylmuramate kinase	371
2918278509	417	98.51	4	417	5	402	0.0e+00	458.4	COG0162	Tyrosyl-tRNA synthetase	401
2918278511	994	92.42	10	927	28	917	0.0e+00	903.9	COG1391	Glutamine synthetase adenylyltransferase	963
2918278512	154	96.82	1	154	3	154	4.5e-65	212.9	COG1225	Peroxiredoxin	157
2918278513	228	92.66	4	212	14	215	1.4e-34	114	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2918278515	220	20.08	7	74	3	55	4.5e-35	60.2	COG1192	Cellulose biosynthesis protein BcsQ	259
2918278515	220	53.03	70	220	119	258	4.5e-35	54.9	COG1192	Cellulose biosynthesis protein BcsQ	259
2918278516	323	94.81	2	213	10	210	5.4e-73	239	COG0009	tRNA A37 threonylcarbamoyladenosine synthetase subunit TsaC/SUA5/YrdC	211
2918278517	473	99.15	11	473	3	467	5.0e-127	419.2	COG0277	FAD/FMN-containing dehydrogenase	459
2918278518	653	16.47	31	277	79	148	5.9e-61	23.4	COG0840	Methyl-accepting chemotaxis protein	408
2918278518	653	62.35	346	648	159	423	5.9e-61	176.6	COG0840	Methyl-accepting chemotaxis protein	408
2918278521	599	97.49	17	461	7	395	1.3e-107	354.5	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918278523	133	88.5	7	118	7	106	3.0e-18	60.4	COG4828	Uncharacterized membrane protein	113
2918278524	247	92.83	18	245	9	228	1.9e-41	136.8	COG1183	Phosphatidylserine synthase	234
2918278525	452	99	15	427	4	400	4.5e-93	306.9	COG0247	Fe-S oxidoreductase	388
2918278526	403	91.68	3	403	38	467	1.2e-51	170.5	COG0277	FAD/FMN-containing dehydrogenase	459
2918278527	495	99.57	20	471	2	468	8.2e-128	421.8	COG0277	FAD/FMN-containing dehydrogenase	459
2918278528	41	100	1	41	1	38	3.9e-20	66.3	COG0257	Ribosomal protein L36	38
2918278529	317	39.86	88	307	64	177	3.1e-13	43.8	COG2230	Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases	283
2918278530	309	85.21	22	299	36	277	2.2e-88	290.5	COG3770	Murein endopeptidase	284
2918278531	279	96.27	17	268	10	293	1.5e-25	84.6	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918278532	377	70.65	91	376	81	287	5.7e-33	109.2	COG0842	ABC-type multidrug transport system, permease component	286
2918278534	306	99.67	1	300	1	305	3.0e-85	281	COG1131	ABC-type multidrug transport system, ATPase component	293
2918278535	314	67.33	25	276	47	283	1.0e-27	91.1	COG1566	Multidrug resistance efflux pump	352
2918278536	219	95.69	7	216	6	205	2.3e-29	98.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918278537	625	94.18	3	625	32	549	0.0e+00	566.2	COG3604	Transcriptional regulator containing GAF, AAA-type ATPase, and DNA-binding Fis domains	550
2918278538	295	74.59	2	172	54	235	1.3e-32	107.3	COG2114	Adenylate cyclase, class 3	227
2918278539	518	92.74	48	445	2	333	6.9e-63	207.3	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
2918278540	63	54.03	1	63	37	103	5.1e-11	37.2	COG1145	Ferredoxin	99
2918278541	170	22.28	2	168	137	218	1.2e-03	13.8	COG0457	Tetratricopeptide (TPR) repeat	291
2918278545	384	97.93	1	384	1	378	0.0e+00	446.2	COG1104	Cysteine sulfinate desulfinase/cysteine desulfurase or related enzyme	386
2918278546	69	94.2	1	69	1	65	4.7e-29	94.9	COG5554	Nitrogen fixation protein	69
2918278548	393	97.6	13	384	6	371	3.5e-93	307.1	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
2918278550	208	98.51	1	203	3	201	9.0e-73	238.6	COG1182	FMN-dependent NADH-azoreductase	202
2918278551	255	97.27	1	255	1	249	7.4e-85	279.3	COG0121	Predicted glutamine amidotransferase	252
2918278552	141	96.58	2	115	3	115	7.9e-13	43.2	COG1393	Arsenate reductase and related proteins, glutaredoxin family	117
2918278553	297	21.97	196	284	236	304	2.0e-46	57.3	COG1397	ADP-ribosylglycohydrolase	314
2918278553	297	58.92	1	206	5	189	2.0e-46	94.5	COG1397	ADP-ribosylglycohydrolase	314
2918278556	293	99.28	3	281	2	277	0.0e+00	441.1	COG1348	Nitrogenase subunit NifH, an ATPase	278
2918278557	479	96.29	24	477	2	442	0.0e+00	483.9	COG2710	Nitrogenase molybdenum-iron protein, alpha and beta chains	456
2918278558	519	98.25	38	518	5	454	1.9e-120	397.1	COG2710	Nitrogenase molybdenum-iron protein, alpha and beta chains	456
2918278559	463	95.2	2	462	18	453	8.1e-115	378.6	COG2710	Nitrogenase molybdenum-iron protein, alpha and beta chains	456
2918278560	460	91.05	4	444	24	440	3.9e-80	264.1	COG2710	Nitrogenase molybdenum-iron protein, alpha and beta chains	456
2918278561	133	83.47	1	111	1	101	9.7e-04	13.6	COG1433	Predicted Fe-Mo cluster-binding protein, NifX family	121
2918278563	68	92.96	1	67	5	70	1.1e-22	74.6	COG5420	Uncharacterized protein	71
2918278564	97	38.29	14	96	50	116	1.9e-11	38.1	COG1143	Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)	172
2918278566	128	96.36	1	106	4	109	1.0e-38	126	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
2918278567	307	83.87	220	301	6	83	1.4e-19	61.3	COG0694	Fe-S cluster biogenesis protein NfuA, 4Fe-4S-binding domain	93
2918278567	307	88.89	135	197	3	58	1.9e-08	29.3	COG2906	Bacterioferritin-associated ferredoxin	63
2918278567	307	92.72	1	129	6	145	1.2e-43	142.7	COG0822	NifU homolog involved in Fe-S cluster formation	150
2918278568	401	99.22	3	387	3	385	0.0e+00	498.4	COG1104	Cysteine sulfinate desulfinase/cysteine desulfurase or related enzyme	386
2918278569	375	89.1	6	373	4	371	1.1e-114	378.1	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
2918278570	270	88.27	10	207	6	178	7.9e-78	254.8	COG1045	Serine acetyltransferase	194
2918278572	576	72.28	5	289	63	328	2.1e-22	71.3	COG0457	Tetratricopeptide (TPR) repeat	291
2918278573	283	97.32	1	269	1	254	1.9e-81	267.6	COG2086	Electron transfer flavoprotein, alpha and beta subunits	260
2918278574	359	99.37	22	351	2	317	3.7e-103	340.2	COG2025	Electron transfer flavoprotein, alpha subunit	313
2918278575	433	99.51	2	432	2	406	2.2e-109	360.8	COG0644	Dehydrogenase (flavoprotein)	396
2918278576	97	94.95	1	97	6	99	1.0e-39	129.5	COG2440	Ferredoxin-like protein FixX	99
2918278578	663	88	79	548	43	416	1.9e-57	189	COG0840	Methyl-accepting chemotaxis protein	408
2918278579	1000	68.42	27	164	6	96	1.1e-46	36.2	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918278579	1000	72	879	999	19	108	9.1e-13	41.9	COG2198	HPt (histidine-containing phosphotransfer) domain	122
2918278579	1000	73.86	229	594	98	388	3.3e-83	275.2	COG0642	Signal transduction histidine kinase	336
2918278579	1000	93.23	742	873	6	129	1.1e-46	113.9	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918278580	532	31.62	30	202	14	130	9.0e-82	13.1	COG3437	Response regulator c-di-GMP phosphodiesterase, RpfG family, contains REC and HD-GYP domains	360
2918278580	532	55.68	313	529	165	370	9.0e-82	254.8	COG3437	Response regulator c-di-GMP phosphodiesterase, RpfG family, contains REC and HD-GYP domains	360
2918278581	112	45.59	26	97	11	41	2.0e-04	15.7	COG2104	Sulfur carrier protein ThiS (thiamine biosynthesis)	68
2918278583	227	87.88	25	210	8	181	1.7e-40	133	COG4725	N6-adenosine-specific RNA methylase IME4	198
2918278585	247	94.95	21	227	2	208	2.3e-38	126.4	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2918278587	265	97.74	5	262	7	265	5.6e-64	210.7	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918278588	402	98.5	1	397	7	401	0.0e+00	473.3	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2918278589	192	94.03	126	192	3	65	9.8e-56	95.5	COG1278	Cold shock protein, CspA family	67
2918278589	192	95.52	19	85	3	66	9.8e-56	83.7	COG1278	Cold shock protein, CspA family	67
2918278590	304	34.11	47	284	302	492	3.8e-23	76.7	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918278591	569	75	36	562	64	426	1.4e-42	140.6	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
2918278592	731	97.69	18	728	6	725	1.3e-128	424.9	COG0507	ATP-dependent exoDNAse (exonuclease V), alpha subunit, helicase superfamily I	696
2918278593	724	99.65	5	722	1	574	0.0e+00	765.9	COG2225	Malate synthase	545
2918278594	381	87.07	3	379	22	378	4.6e-58	191.3	COG4645	Uncharacterized protein	410
2918278596	285	95.93	54	272	5	216	1.9e-19	65	COG2755	Lysophospholipase L1 or related esterase	216
2918278598	322	95.22	24	320	4	262	9.7e-84	275	COG3741	N-formylglutamate amidohydrolase	272
2918278599	766	96.39	10	766	15	388	1.1e-21	68.8	COG1344	Flagellin and related hook-associated protein FlgL	360
2918278602	464	95.72	1	463	15	484	0.0e+00	506.9	COG0380	Trehalose-6-phosphate synthase	486
2918278603	323	98.12	7	323	6	319	8.9e-116	380.9	COG0837	Glucokinase	320
2918278604	474	93.42	154	468	11	223	5.4e-53	174.1	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
2918278605	197	75.25	9	196	40	191	4.7e-29	89.5	COG1573	Uracil-DNA glycosylase	202
2918278606	132	86.14	20	116	11	97	1.6e-23	77	COG2154	Pterin-4a-carbinolamine dehydratase	101
2918278607	680	29.61	466	680	454	644	0.0e+00	179.4	COG0323	DNA mismatch repair ATPase MutL	638
2918278607	680	53.95	61	454	1	348	0.0e+00	443.8	COG0323	DNA mismatch repair ATPase MutL	638
2918278608	1407	20.75	917	1125	258	346	9.6e-23	17.2	COG0823	Periplasmic component of the Tol biopolymer transport system	425
2918278608	1407	21.91	1143	1284	267	360	9.6e-23	7.6	COG0823	Periplasmic component of the Tol biopolymer transport system	425
2918278608	1407	23.78	433	597	246	347	9.6e-23	15.6	COG0823	Periplasmic component of the Tol biopolymer transport system	425
2918278608	1407	30.54	1030	1221	217	347	9.6e-23	20.5	COG0823	Periplasmic component of the Tol biopolymer transport system	425
2918278608	1407	37.3	604	807	202	361	9.6e-23	45.4	COG0823	Periplasmic component of the Tol biopolymer transport system	425
2918278609	120	88.72	1	119	5	122	2.1e-18	61.2	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918278610	268	80.21	1	259	32	258	1.8e-09	30.2	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918278611	137	29.96	15	137	156	238	2.9e-07	25.1	COG2857	Cytochrome c1	250
2918278613	202	90.14	1	200	19	210	1.5e-26	87.6	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
2918278614	645	92.62	29	577	7	533	0.0e+00	678.2	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
2918278615	314	85.43	1	239	22	238	3.4e-59	194.4	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
2918278616	189	70.73	18	161	33	148	1.5e-18	62	COG2010	Cytochrome c, mono- and diheme variants	150
2918278617	603	84.09	1	601	123	772	1.3e-116	384.5	COG4993	Glucose dehydrogenase	773
2918278618	207	96.67	1	207	1	203	9.1e-72	235.8	COG2808	Predicted FMN-binding regulatory protein PaiB	209
2918278619	270	64.39	121	270	40	124	1.3e-22	74.5	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918278620	156	93.38	5	156	6	146	8.0e-34	110.5	COG3238	Uncharacterized membrane protein YdcZ, DUF606 family	150
2918278621	553	97.49	10	512	1	504	1.4e-103	342.5	COG0366	Glycosidase	505
2918278622	375	15.36	256	358	402	487	2.5e-24	53.9	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918278622	375	18.04	43	283	346	446	2.5e-24	40.7	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918278623	189	98.4	1	188	2	186	3.3e-49	161.6	COG0742	16S rRNA G966 N2-methylase RsmD	187
2918278624	395	94.72	16	252	3	235	1.0e-70	232.2	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
2918278625	68	95.77	1	68	1	68	4.8e-32	105.1	COG3360	Flavin-binding protein dodecin	71
2918278626	150	94.77	1	148	8	152	3.5e-49	161.5	COG0590	tRNA(Arg) A34 adenosine deaminase TadA	152
2918278628	126	55.07	1	51	1	38	1.8e-11	10.5	COG1942	Phenylpyruvate tautomerase PptA, 4-oxalocrotonate tautomerase family	69
2918278628	126	73.91	66	124	5	55	1.8e-11	26.2	COG1942	Phenylpyruvate tautomerase PptA, 4-oxalocrotonate tautomerase family	69
2918278629	284	97.67	5	284	1	294	1.4e-47	157.6	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918278630	429	98.83	1	429	1	424	0.0e+00	562.5	COG0151	Phosphoribosylamine-glycine ligase	428
2918278631	539	39.1	331	509	267	440	0.0e+00	66.9	COG1570	Exonuclease VII, large subunit	440
2918278631	539	74.83	19	361	4	336	0.0e+00	431.8	COG1570	Exonuclease VII, large subunit	440
2918278632	262	53.41	64	255	10	158	4.1e-05	18.1	COG0500	SAM-dependent methyltransferase	257
2918278634	351	98.84	2	348	3	342	0.0e+00	490.7	COG0418	Dihydroorotase	344
2918278635	451	98.61	3	449	4	429	1.7e-120	397.1	COG0124	Histidyl-tRNA synthetase	429
2918278636	300	84.13	24	300	48	328	1.6e-68	226	COG2367	Beta-lactamase class A	329
2918278637	289	97.34	6	289	2	294	3.1e-64	212.2	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918278638	327	82.22	3	314	5	286	6.0e-18	59.7	COG3594	Fucose 4-O-acetylase or related acetyltransferase	343
2918278639	1008	99.3	49	941	2	709	8.6e-77	253.8	COG0744	Membrane carboxypeptidase (penicillin-binding protein)	661
2918278640	213	93.42	1	145	7	148	2.3e-47	154.6	COG3772	Phage-related lysozyme (muramidase), GH24 family	152
2918278641	125	79.31	1	98	21	112	8.7e-28	91.3	COG3339	Uncharacterized membrane protein YkvA, DUF1232 family	116
2918278646	81	71.76	5	80	13	73	1.9e-03	13.2	COG4040	Uncharacterized membrane protein	85
2918278647	273	96.11	26	265	3	249	1.8e-62	205.5	COG1058	Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA	255
2918278648	213	85.11	1	213	30	229	1.4e-68	225.5	COG1489	DNA-binding protein, stimulates sugar fermentation	235
2918278649	277	98.71	9	260	3	308	1.6e-88	291.5	COG0024	Methionine aminopeptidase	255
2918278650	258	96.88	30	258	8	224	3.0e-73	240.5	COG2003	DNA repair protein RadC, contains a helix-hairpin-helix DNA-binding motif	224
2918278651	214	98.96	1	191	2	191	8.5e-72	235.2	COG0450	Alkyl hydroperoxide reductase subunit AhpC (peroxiredoxin)	194
2918278652	286	89.62	1	265	19	251	2.0e-47	156.5	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2918278653	1082	30.72	65	249	50	190	1.1e-40	79.7	COG4564	Signal transduction histidine kinase	459
2918278653	1082	31.59	235	414	76	220	1.1e-40	54.3	COG4564	Signal transduction histidine kinase	459
2918278653	1082	64.56	600	1080	215	642	8.4e-111	365.2	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2918278654	431	99.54	1	431	1	437	0.0e+00	560.2	COG0015	Adenylosuccinate lyase	438
2918278656	106	100	1	106	1	104	1.5e-32	106.8	COG5467	Uncharacterized protein	104
2918278658	254	93.09	1	244	8	263	7.6e-82	269	COG0152	Phosphoribosylaminoimidazole-succinocarboxamide synthase	247
2918278659	80	95.18	1	80	2	80	2.2e-35	115.4	COG1828	Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component	83
2918278660	205	65.74	2	204	98	287	4.5e-53	175.1	COG0122	3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase	285
2918278661	228	98.6	4	217	3	213	3.9e-73	240.2	COG2258	Uncharacterized conserved protein YiiM, contains MOSC domain	210
2918278662	391	92.41	2	389	22	386	5.0e-02	6.4	COG2814	Predicted arabinose efflux permease, MFS family	394
2918278663	294	98.01	6	294	2	296	2.6e-61	202.6	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918278664	409	98.3	5	406	3	407	3.8e-98	323.5	COG0004	Ammonia channel protein AmtB	409
2918278665	229	98.36	1	229	3	242	2.8e-84	276.8	COG0047	Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain	231
2918278666	737	97.23	2	726	17	752	0.0e+00	871.3	COG0046	Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain	743
2918278669	79	94.44	1	79	1	85	2.4e-24	80.2	COG0271	Stress-induced morphogen (activity unknown)	90
2918278670	113	98.1	3	106	2	104	4.5e-48	156	COG0278	Glutaredoxin-related protein	105
2918278674	132	55.45	9	132	2	118	3.3e-19	64	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918278675	397	96.05	176	397	5	223	8.8e-50	163.4	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
2918278676	309	97.29	7	303	8	294	2.3e-95	313.9	COG2962	Uncharacterized membrane protein RarD, contains two EamA domains	293
2918278677	220	96.65	18	220	5	206	1.6e-23	79	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918278678	367	98.9	1	367	2	360	2.3e-117	387	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
2918278679	204	100	1	204	1	210	7.3e-59	193.6	COG0522	Ribosomal protein S4 or related protein	205
2918278680	413	96.61	1	408	14	412	6.4e-80	262.3	COG2133	Glucose/arabinose dehydrogenase, beta-propeller fold	399
2918278683	256	95.97	12	256	4	241	9.5e-75	246	COG0565	tRNA C32,U32 (ribose-2'-O)-methylase TrmJ or a related methyltransferase	242
2918278684	543	97.82	13	438	2	405	1.1e-116	384.7	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
2918278685	138	93.98	6	134	6	130	7.7e-18	59.2	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918278686	611	70.56	183	592	112	389	1.9e-54	180.6	COG0642	Signal transduction histidine kinase	336
2918278687	301	99	20	296	1	298	3.7e-48	159.4	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918278688	198	87.38	20	191	5	184	9.8e-33	108	COG1335	Nicotinamidase-related amidase	205
2918278689	154	38.94	6	146	84	171	1.0e-07	26	COG1738	Uncharacterized PurR-regulated membrane protein YhhQ, DUF165 family	233
2918278690	394	88.92	13	370	3	307	2.3e-10	31.1	COG3594	Fucose 4-O-acetylase or related acetyltransferase	343
2918278691	457	99.57	2	457	2	464	0.0e+00	593.8	COG0215	Cysteinyl-tRNA synthetase	464
2918278692	455	97.08	1	452	9	474	2.4e-114	376.9	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
2918278693	850	23.53	218	427	43	142	3.4e-104	18.9	COG0840	Methyl-accepting chemotaxis protein	408
2918278693	850	77.88	432	848	94	424	3.4e-104	327	COG0840	Methyl-accepting chemotaxis protein	408
2918278694	245	95.5	4	217	5	216	4.8e-39	129	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
2918278696	575	98.27	1	563	8	575	0.0e+00	641.8	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
2918278697	294	95.76	11	293	13	283	3.3e-76	250.9	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
2918278698	318	95.97	21	315	7	292	1.4e-86	285.1	COG1175	ABC-type sugar transport system, permease component	295
2918278699	449	98.19	13	449	6	440	6.9e-43	142.2	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
2918278700	357	99.71	1	352	1	349	0.0e+00	489.3	COG3839	ABC-type sugar transport system, ATPase component	338
2918278702	343	90.49	4	343	3	316	2.7e-95	313.8	COG0123	Acetoin utilization deacetylase AcuC or a related deacetylase	340
2918278703	131	93.98	1	131	5	129	2.4e-21	70.7	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918278704	997	19.28	875	967	127	174	1.4e-51	26.5	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
2918278704	997	20.88	662	738	135	186	1.4e-51	19.9	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
2918278704	997	29.72	738	886	130	203	1.4e-51	32.3	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
2918278704	997	34.14	538	650	137	221	1.4e-51	6	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
2918278704	997	42.57	230	427	119	224	1.4e-51	20.2	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
2918278704	997	69.08	73	247	41	212	1.4e-51	78.9	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
2918278705	261	32.59	16	198	23	139	1.9e-10	36	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
2918278706	155	69.23	27	147	2	91	1.2e-18	62.5	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918278707	544	94.59	362	543	2	176	5.9e-70	228.2	COG1838	Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain	184
2918278707	544	99	41	347	2	297	4.1e-87	286.4	COG1951	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain	297
2918278708	231	73.29	1	216	78	291	4.8e-58	191.6	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
2918278709	1133	98.6	2	1117	11	1134	0.0e+00	994.8	COG1197	Transcription-repair coupling factor (superfamily II helicase)	1139
2918278710	372	72.1	1	331	13	242	3.5e-37	122.7	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
2918278712	215	95.26	17	206	2	182	6.6e-81	265.2	COG3005	Tetraheme cytochrome c subunit of nitrate or TMAO reductase	190
2918278713	150	74.19	1	150	38	152	4.9e-44	144.8	COG3043	Nitrate reductase cytochrome c-type subunit	155
2918278714	298	67	18	287	4	269	1.1e-49	163.8	COG0348	Polyferredoxin	386
2918278715	262	20.97	159	224	35	60	7.6e-15	16.7	COG1145	Ferredoxin	99
2918278715	262	50	122	198	38	99	7.6e-15	15.3	COG1145	Ferredoxin	99
2918278715	262	54.03	12	134	43	109	7.6e-15	36.4	COG1145	Ferredoxin	99
2918278716	830	99.88	2	830	1	809	0.0e+00	723.5	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
2918278717	102	86.17	14	102	7	87	2.1e-16	54.2	COG3062	Cytoplasmic chaperone NapD for the signal peptide of periplasmic nitrate reductase NapAB	94
2918278718	180	57.26	91	180	43	113	6.5e-19	28.3	COG1145	Ferredoxin	99
2918278718	180	58.06	8	106	37	108	6.5e-19	38.6	COG1145	Ferredoxin	99
2918278719	489	82.99	117	483	63	389	2.8e-60	199.7	COG0642	Signal transduction histidine kinase	336
2918278720	214	98.58	1	212	1	208	3.2e-51	168.6	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918278721	215	95.77	2	213	3	206	1.8e-82	270.4	COG4136	ABC-type uncharacterized transport system YnjBCD, ATPase component	213
2918278722	555	98	4	555	11	550	0.0e+00	477.1	COG4135	ABC-type uncharacterized transport system YnjBCD, permease component	551
2918278724	397	97.92	1	397	7	382	1.7e-123	407.1	COG4134	ABC-type uncharacterized transport system YnjBCD, periplasmic component	384
2918278725	203	95.26	1	203	4	204	9.0e-27	88.5	COG3222	Uncharacterized conserved protein, glycosyltransferase A (GT-A) superfamily, DUF2064 family	211
2918278726	221	26.74	1	207	3	98	1.2e-09	33.2	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
2918278727	340	74.37	158	340	50	197	3.5e-34	113.1	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
2918278728	346	88.46	21	323	21	250	3.8e-34	112.5	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2918278731	366	97.27	12	366	4	359	2.1e-91	301.3	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918278733	236	98.73	1	234	3	236	5.1e-99	324.8	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2918278734	299	99.21	12	274	3	254	1.9e-98	323.3	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2918278735	505	93.5	145	475	17	318	9.5e-96	315.6	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918278736	301	99.34	1	300	2	300	4.6e-97	319.8	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2918278738	309	97.1	1	308	7	307	1.3e-80	265.5	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
2918278740	561	90.49	21	534	10	504	1.1e-62	207.2	COG1807	4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferase of PMT family	535
2918278741	111	86.73	1	105	11	108	1.0e-33	110.1	COG3952	Uncharacterized N-terminal domain of lipid-A-disaccharide synthase	113
2918278742	248	52.37	10	240	4	191	6.2e-24	80.3	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
2918278743	512	25.48	411	512	266	358	1.1e-127	35.7	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
2918278743	512	96.16	15	395	11	361	1.1e-127	389.7	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
2918278744	278	41.77	214	276	27	59	2.9e-02	9.6	COG4238	Outer membrane murein-binding lipoprotein Lpp	78
2918278744	278	65.81	25	128	21	97	1.8e-05	19.9	COG2963	Transposase and inactivated derivatives	116
2918278745	74	94.74	1	74	1	72	3.4e-26	86.2	COG4572	Cation transport regulator ChaB	76
2918278748	239	91.84	1	235	10	234	2.1e-61	202	COG0704	Phosphate uptake regulator	240
2918278749	437	24.3	359	430	121	181	7.8e-96	57.7	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2918278749	437	37.45	17	121	108	201	7.8e-96	80.5	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2918278749	437	39.44	246	362	105	203	7.8e-96	80.7	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2918278749	437	53.39	111	255	75	208	7.8e-96	114.4	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2918278751	167	95.49	26	156	4	130	5.0e-25	82.6	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918278752	298	97.48	7	291	2	272	2.4e-78	257.7	COG0388	Predicted amidohydrolase	274
2918278754	325	91.62	1	325	8	324	2.9e-108	356.8	COG1171	Threonine dehydratase	347
2918278755	247	98.13	1	247	5	267	3.4e-64	211.7	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918278756	310	98.95	9	294	4	286	2.1e-89	294.1	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
2918278757	269	75.33	23	268	43	268	5.9e-43	141.6	COG3336	Cytochrome c oxidase assembly factor CtaG	299
2918278758	174	91.98	2	173	7	178	9.2e-29	95.5	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
2918278759	531	49.17	5	117	124	242	1.3e-40	40.3	COG2202	PAS domain	232
2918278759	531	52.07	239	359	117	242	1.3e-40	50.3	COG2202	PAS domain	232
2918278759	531	57.02	99	240	100	237	1.3e-40	46.7	COG2202	PAS domain	232
2918278759	531	97.81	347	527	5	183	9.9e-58	189.2	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2918278760	356	95.84	23	355	11	356	1.6e-71	235.4	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
2918278761	320	96.25	2	320	8	315	2.7e-104	343.1	COG1270	Cobalamin biosynthesis protein CobD/CbiB	320
2918278762	131	98.47	1	131	1	129	8.0e-42	137.5	COG3742	Uncharacterized protein, contains PIN domain	131
2918278763	83	97.56	1	81	1	80	2.7e-19	64.5	COG4423	Uncharacterized protein	81
2918278764	485	98.97	1	485	3	483	0.0e+00	658.1	COG1492	Cobyric acid synthase	486
2918278765	206	98.48	10	206	4	198	4.9e-82	269	COG2109	ATP:corrinoid adenosyltransferase	198
2918278766	174	98.86	4	171	2	174	3.2e-61	200.6	COG2087	Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase	175
2918278767	324	98.75	6	317	3	319	3.1e-78	258.1	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2918278768	214	42.03	19	206	152	275	2.2e-06	19.1	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918278769	256	91.19	2	245	24	292	4.4e-26	86.6	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918278770	626	90.23	382	624	6	125	7.4e-26	84.2	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918278771	866	82.49	314	732	68	392	1.2e-54	181.2	COG0642	Signal transduction histidine kinase	336
2918278772	208	95.35	1	207	2	206	2.1e-36	120.4	COG0625	Glutathione S-transferase	211
2918278773	658	93.23	527	653	4	127	1.9e-26	85.9	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918278774	689	66.5	197	547	131	392	8.2e-53	174.1	COG0642	Signal transduction histidine kinase	336
2918278774	689	90.23	565	689	7	126	3.0e-22	72.3	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918278775	143	94.02	2	115	3	112	3.1e-11	38	COG1393	Arsenate reductase and related proteins, glutaredoxin family	117
2918278776	339	97.61	1	338	5	331	6.4e-68	224.1	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918278777	269	94.96	2	262	12	256	2.6e-74	244.4	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2918278778	280	96.02	14	273	7	247	1.8e-89	294.1	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2918278779	260	54.63	10	211	41	211	1.4e-23	77.7	COG3509	Poly(3-hydroxybutyrate) depolymerase	312
2918278780	222	38.37	6	215	91	184	4.2e-05	18	COG3904	Predicted periplasmic protein	245
2918278781	196	47.53	2	186	74	179	6.2e-08	27.5	COG1226	Voltage-gated potassium channel Kch	212
2918278782	394	92.17	10	393	26	390	3.2e-79	261.2	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
2918278783	242	33.09	1	96	1	90	9.7e-39	60.2	COG0561	Hydroxymethylpyrimidine pyrophosphatase and other HAD family phosphatases	264
2918278783	242	36.4	96	221	171	269	9.7e-39	66.5	COG0561	Hydroxymethylpyrimidine pyrophosphatase and other HAD family phosphatases	264
2918278784	409	89.31	32	407	21	329	3.0e-68	224.7	COG1171	Threonine dehydratase	347
2918278785	93	87.06	2	83	9	82	3.2e-18	59.9	COG3750	Uncharacterized conserved protein, UPF0335 family	85
2918278786	112	51.16	2	112	51	116	3.6e-10	34.4	COG0662	Mannose-6-phosphate isomerase, cupin superfamily	127
2918278787	100	51.77	4	91	68	140	9.7e-24	79.2	COG1886	Flagellar motor switch/type III secretory pathway protein FliN	136
2918278788	282	97.21	1	279	8	286	2.3e-60	198.5	COG2897	3-mercaptopyruvate sulfurtransferase SseA, contains two rhodanese domains	285
2918278789	516	97.88	1	509	7	513	0.0e+00	516.7	COG0728	Peptidoglycan biosynthesis protein MviN/MurJ, putative lipid II flippase	518
2918278790	259	95.93	2	259	9	291	2.1e-42	140.3	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918278792	231	39.78	50	227	60	168	4.2e-04	14.8	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
2918278793	173	93.23	45	169	6	129	5.5e-17	56.2	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918278794	452	96.92	13	443	12	389	5.2e-34	112.6	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918278795	535	88.97	1	527	42	557	0.0e+00	463.6	COG4618	ABC-type protease/lipase transport system, ATPase and permease components	580
2918278796	509	99.2	2	501	3	496	0.0e+00	688.7	COG2986	Histidine ammonia-lyase	498
2918278797	176	97.59	1	173	5	166	1.9e-67	220.4	COG0678	Peroxiredoxin	165
2918278798	74	87.5	1	73	1	63	2.9e-30	98.3	COG3205	Uncharacterized membrane protein	72
2918278799	262	92.98	2	234	2	213	1.0e-56	186.9	COG0705	Membrane associated serine protease, rhomboid family	228
2918278800	346	16.18	25	170	285	351	2.3e-07	17.4	COG4099	Predicted peptidase	387
2918278800	346	18.36	209	314	181	256	2.3e-07	5.1	COG4099	Predicted peptidase	387
2918278801	425	98.59	1	425	1	419	0.0e+00	677.2	COG0148	Enolase	423
2918278802	309	28.94	191	309	191	269	5.6e-32	27.3	COG1235	Phosphoribosyl 1,2-cyclic phosphodiesterase	269
2918278802	309	38.1	1	189	4	107	5.6e-32	77.1	COG1235	Phosphoribosyl 1,2-cyclic phosphodiesterase	269
2918278803	258	92.98	1	246	7	231	4.8e-63	207.3	COG5424	Pyrroloquinoline quinone (PQQ) biosynthesis protein C	242
2918278805	368	93.85	6	343	19	354	6.6e-61	200.9	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
2918278807	151	48.1	8	135	81	156	1.5e-18	62	COG1555	DNA uptake protein ComE and related DNA-binding proteins	149
2918278809	275	96.77	2	275	3	272	0.0e+00	449.3	COG2877	3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase	279
2918278810	231	98.73	1	231	3	236	5.4e-61	200.7	COG0412	Dienelactone hydrolase	236
2918278811	543	99.07	2	542	2	531	0.0e+00	798.3	COG0504	CTP synthase (UTP-ammonia lyase)	533
2918278812	110	93.55	1	98	1	87	2.9e-26	85.8	COG1314	Preprotein translocase subunit SecG	86
2918278813	251	97.22	3	251	2	246	9.1e-89	291.7	COG0149	Triosephosphate isomerase	251
2918278814	627	30.77	386	520	205	304	2.1e-25	14.4	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
2918278814	627	90.77	8	396	4	298	2.1e-25	75.4	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
2918278815	503	98.72	21	501	3	463	0.0e+00	549.9	COG0147	Anthranilate/para-aminobenzoate synthases component I	462
2918278816	267	90.99	8	118	3	103	3.4e-01	10.7	COG3136	Uncharacterized membrane protein, GlpM family	111
2918278817	68	91.78	1	66	4	70	7.2e-15	49.9	COG2608	Copper chaperone CopZ	71
2918278818	373	87.45	134	372	28	250	7.6e-74	242.3	COG2861	Uncharacterized conserved protein YibQ, putative polysaccharide deacetylase 2 family	250
2918278820	197	98.43	1	189	3	190	1.3e-76	251	COG0512	Anthranilate/para-aminobenzoate synthase component II	191
2918278821	349	99.12	9	345	3	339	0.0e+00	441.7	COG0547	Anthranilate phosphoribosyltransferase	338
2918278822	262	99.61	5	262	1	253	3.6e-99	325.7	COG0134	Indole-3-glycerol phosphate synthase	254
2918278823	152	53.97	5	144	64	165	1.9e-15	51.9	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
2918278824	159	98.08	1	158	2	154	2.7e-66	216.8	COG0315	Molybdenum cofactor biosynthesis enzyme	157
2918278825	407	98.03	1	404	6	404	2.4e-128	422.8	COG0303	Molybdopterin biosynthesis enzyme	404
2918278826	232	98.52	1	232	3	202	4.9e-69	226.6	COG1974	SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase)	201
2918278827	731	96.21	40	570	12	468	8.7e-50	164.4	COG0658	Predicted membrane metal-binding protein	453
2918278828	470	97.5	1	466	9	476	0.0e+00	503.9	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
2918278829	437	99.75	33	436	2	396	0.0e+00	558.3	COG0372	Citrate synthase	390
2918278831	202	92.09	2	200	2	199	1.4e-48	160.1	COG0625	Glutathione S-transferase	211
2918278832	175	78.4	17	159	31	157	2.0e-11	39.1	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2918278833	131	99.32	4	129	2	146	8.1e-25	83.5	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2918278834	394	98.68	3	385	4	378	1.3e-126	417	COG0763	Lipid A disaccharide synthetase	381
2918278835	285	97.49	3	275	6	277	3.4e-86	283.5	COG3494	Uncharacterized conserved protein, DUF1009 family	279
2918278836	264	98.08	1	259	4	258	6.5e-112	367.5	COG1043	Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase	260
2918278837	156	96.62	10	156	4	146	8.8e-54	176	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
2918278838	191	97.06	5	180	5	169	4.9e-22	73.4	COG2825	Periplasmic chaperone for outer membrane proteins, Skp family	170
2918278839	764	97.67	4	764	19	774	0.0e+00	743.2	COG4775	Outer membrane protein assembly factor BamA	766
2918278840	374	98.76	4	364	3	399	1.7e-88	292.2	COG0750	Membrane-associated protease RseP, regulator of RpoE activity	375
2918278841	401	98.19	17	400	2	380	0.0e+00	510.3	COG0743	1-deoxy-D-xylulose 5-phosphate reductoisomerase	385
2918278842	293	98.55	33	289	2	272	1.3e-61	203.3	COG0575	CDP-diglyceride synthetase	265
2918278843	246	92.06	1	240	20	251	1.6e-97	320.5	COG0020	Undecaprenyl pyrophosphate synthase	245
2918278844	185	95.72	3	185	9	187	5.1e-76	248.8	COG0233	Ribosome recycling factor	187
2918278845	251	98.32	14	248	4	237	1.4e-96	317.1	COG0528	Uridylate kinase	238
2918278846	309	99.33	1	308	1	295	9.2e-111	364.3	COG0264	Translation elongation factor EF-Ts	296
2918278847	261	94.53	1	261	7	248	6.8e-105	344.4	COG0052	Ribosomal protein S2	252
2918278850	1160	98.27	3	1157	3	1139	0.0e+00	1316	COG0587	DNA polymerase III, alpha subunit	1139
2918278852	292	96.35	1	289	7	296	1.6e-46	153.6	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918278853	285	98.31	61	285	4	236	3.2e-59	194.7	COG0412	Dienelactone hydrolase	236
2918278854	231	97.79	5	229	1	221	3.3e-80	263.1	COG1136	ABC-type lipoprotein export system, ATPase component	226
2918278855	415	99.76	2	415	2	410	0.0e+00	453.8	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
2918278856	437	32.45	243	437	356	526	0.0e+00	177	COG0442	Prolyl-tRNA synthetase	500
2918278856	437	42.88	1	244	1	226	0.0e+00	359	COG0442	Prolyl-tRNA synthetase	500
2918278859	199	96.28	3	170	2	182	1.8e-51	160.5	COG2818	3-methyladenine DNA glycosylase Tag	188
2918278860	85	93.26	1	84	1	83	4.9e-20	66.4	COG5454	Predicted secreted protein	89
2918278861	134	97.95	3	133	2	144	5.4e-18	61.3	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2918278862	572	98.35	18	570	7	544	0.0e+00	520.1	COG0595	mRNA degradation ribonuclease J1/J2	555
2918278863	257	100	1	254	1	253	1.4e-83	275	COG1521	Pantothenate kinase type III	251
2918278864	264	98.74	23	260	1	236	2.2e-67	221.7	COG0340	Biotin-(acetyl-CoA carboxylase) ligase	238
2918278865	482	98.32	6	480	7	474	0.0e+00	536.8	COG1007	NADH:ubiquinone oxidoreductase subunit 2 (chain N)	475
2918278866	509	98.39	2	499	2	491	0.0e+00	677.8	COG1008	NADH:ubiquinone oxidoreductase subunit 4 (chain M)	497
2918278867	695	96.43	68	690	22	616	0.0e+00	725.9	COG1009	NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit	606
2918278868	102	99	2	102	2	100	1.8e-38	125.2	COG0713	NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K)	100
2918278869	204	100	1	173	1	168	2.3e-53	174.8	COG0839	NADH:ubiquinone oxidoreductase subunit 6 (chain J)	166
2918278870	162	85.71	2	162	9	158	2.6e-56	184.5	COG1143	Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)	172
2918278871	336	98.5	1	333	4	331	0.0e+00	456.7	COG1005	NADH:ubiquinone oxidoreductase subunit 1 (chain H)	332
2918278872	691	99.59	1	687	1	728	0.0e+00	765.7	COG1034	NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)	693
2918278873	430	97.17	1	421	9	420	0.0e+00	638	COG1894	NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F)	424
2918278874	207	94.58	6	174	8	164	2.0e-63	207.2	COG1905	NADH:ubiquinone oxidoreductase 24 kD subunit (chain E)	160
2918278875	406	98.24	10	406	8	398	0.0e+00	604.2	COG0649	NADH:ubiquinone oxidoreductase 49 kD subunit (chain D)	398
2918278876	209	98.33	1	178	2	178	8.5e-62	203	COG0852	NADH:ubiquinone oxidoreductase 27 kD subunit (chain C)	176
2918278877	180	81.44	14	180	8	165	2.5e-85	279.1	COG0377	NADH:ubiquinone oxidoreductase 20 kD subunit (chhain B) or related Fe-S oxidoreductase	194
2918278878	122	96.72	2	122	4	121	2.0e-47	154.9	COG0838	NADH:ubiquinone oxidoreductase subunit 3 (chain A)	123
2918278882	90	95.74	1	90	2	91	1.3e-35	116.2	COG0776	Bacterial nucleoid DNA-binding protein	94
2918278883	804	98.09	4	781	10	778	0.0e+00	1158.6	COG0466	ATP-dependent Lon protease, bacterial type	782
2918278884	422	98.29	16	420	1	402	0.0e+00	675.1	COG1219	ATP-dependent protease Clp, ATPase subunit	408
2918278885	208	95.5	8	204	3	193	8.7e-91	297.6	COG0740	ATP-dependent protease ClpP, protease subunit	200
2918278886	444	98.88	1	441	1	443	4.5e-130	429	COG0544	FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)	441
2918278889	485	97.57	205	480	7	287	6.4e-78	256.2	COG0063	NAD(P)H-hydrate repair enzyme Nnr, NAD(P)H-hydrate dehydratase domain	284
2918278889	485	98.54	1	194	3	204	1.2e-53	176.5	COG0062	NAD(P)H-hydrate repair enzyme Nnr, NAD(P)H-hydrate epimerase domain	203
2918278890	260	98.43	1	255	4	254	1.8e-72	238.3	COG3836	2-keto-3-deoxy-L-rhamnonate aldolase RhmA	255
2918278892	112	100	1	112	1	112	1.0e-49	162.4	COG0347	Nitrogen regulatory protein PII	112
2918278893	469	99.1	2	469	4	445	0.0e+00	587.1	COG0174	Glutamine synthetase	443
2918278895	181	89.82	1	181	1	203	8.3e-51	167.5	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
2918278898	482	78.81	161	465	51	314	6.4e-23	76.1	COG0582	Integrase	309
2918278899	135	70.79	10	89	2	64	2.0e-08	28.8	COG3609	Transcriptional regulator, contains Arc/MetJ-type RHH (ribbon-helix-helix) DNA-binding domain	89
2918278900	385	92.01	66	382	22	309	2.6e-55	182	COG3509	Poly(3-hydroxybutyrate) depolymerase	312
2918278905	217	93.33	1	214	7	216	3.3e-61	201.5	COG2761	Predicted dithiol-disulfide isomerase, DsbA family	225
2918278906	139	53.56	1	137	101	228	7.9e-31	101.9	COG1186	Protein chain release factor B	239
2918278907	148	68.18	47	117	9	68	7.1e-07	23.4	COG1873	Sporulation protein YlmC, PRC-barrel domain family	87
2918278908	651	35.56	17	156	19	146	6.7e-76	66.8	COG0628	Predicted PurR-regulated permease PerM	355
2918278908	651	56.39	183	408	154	356	6.7e-76	188.3	COG0628	Predicted PurR-regulated permease PerM	355
2918278909	211	30.54	2	209	321	491	2.3e-12	40.4	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918278910	587	68.61	387	567	23	175	2.8e-28	94.1	COG1226	Voltage-gated potassium channel Kch	212
2918278910	587	98.25	1	395	3	395	2.1e-96	317.7	COG0475	Kef-type K+ transport system, membrane component KefB	397
2918278911	235	94.04	10	222	6	210	2.7e-29	96.8	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2918278913	179	93.6	6	170	6	166	1.2e-41	136.8	COG1755	Uncharacterized protein YpbQ, isoprenylcysteine carboxyl methyltransferase (ICMT) family	172
2918278914	348	97.75	4	348	4	351	5.2e-94	309.8	COG3424	Predicted naringenin-chalcone synthase	356
2918278915	244	92.79	28	244	4	209	5.8e-72	236.2	COG2928	Uncharacterized membrane protein	222
2918278916	693	96.76	3	682	9	664	0.0e+00	833.9	COG1200	RecG-like helicase	677
2918278917	472	97.71	2	472	11	480	0.0e+00	651.8	COG5310	Homospermidine synthase	481
2918278918	419	94.68	21	401	21	394	2.5e-71	234.9	COG0019	Diaminopimelate decarboxylase	394
2918278919	275	84.72	2	140	10	131	1.1e-30	36.8	COG2703	Hemerythrin	144
2918278919	275	84.72	141	269	2	123	1.1e-30	62.5	COG2703	Hemerythrin	144
2918278920	188	96.13	1	182	1	174	1.8e-56	185.1	COG1791	Acireductone dioxygenase (methionine salvage), cupin superfamily	181
2918278921	410	93.92	25	410	14	384	3.1e-34	112.7	COG2814	Predicted arabinose efflux permease, MFS family	394
2918278922	665	90.12	194	664	42	424	1.0e-67	223.3	COG0840	Methyl-accepting chemotaxis protein	408
2918278923	399	81.65	4	398	78	424	1.3e-63	209.1	COG0840	Methyl-accepting chemotaxis protein	408
2918278924	303	97.04	22	300	6	267	4.5e-56	183.9	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
2918278925	501	25.45	259	321	89	130	1.9e-39	7.3	COG0835	Chemotaxis signal transduction protein	165
2918278925	501	32.73	158	224	19	72	1.9e-39	13.8	COG0835	Chemotaxis signal transduction protein	165
2918278925	501	55.76	2	124	20	111	1.9e-39	42.8	COG0835	Chemotaxis signal transduction protein	165
2918278925	501	87.88	343	497	14	158	1.9e-39	60.4	COG0835	Chemotaxis signal transduction protein	165
2918278926	357	97.16	5	356	2	343	2.8e-89	294.2	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
2918278927	140	36.36	3	138	2	129	4.2e-32	106.1	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
2918278928	986	98.81	1	975	4	748	0.0e+00	503.2	COG0643	Chemotaxis protein histidine kinase CheA	716
2918278929	172	41.1	15	172	26	182	1.6e-36	120.3	COG3448	CBS-domain-containing membrane protein	382
2918278930	654	65.74	230	654	134	392	3.5e-37	123.2	COG0642	Signal transduction histidine kinase	336
2918278931	290	84.93	7	280	2	125	4.3e-05	18.4	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2918278932	428	97.94	27	411	3	382	1.3e-71	236.4	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918278933	239	99.16	2	236	2	236	4.5e-92	302.1	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2918278934	260	98.82	1	252	3	253	1.3e-97	320.6	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2918278935	331	95.67	3	312	10	318	8.2e-84	276	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918278936	304	97.34	3	303	4	296	2.1e-77	255	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2918278937	373	96.72	11	373	8	361	8.7e-68	223.6	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918278939	308	98.74	1	308	2	315	2.6e-108	357.1	COG2025	Electron transfer flavoprotein, alpha subunit	313
2918278940	249	98.85	1	249	1	258	1.9e-94	310.4	COG2086	Electron transfer flavoprotein, alpha and beta subunits	260
2918278941	170	77.7	24	139	6	113	5.2e-15	50	COG0824	Acyl-CoA thioesterase FadM	137
2918278942	130	84.85	5	128	1	112	9.9e-30	98.1	COG0789	DNA-binding transcriptional regulator, MerR family	124
2918278943	571	96.3	35	571	14	560	2.6e-129	426.7	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2918278944	99	56.72	1	98	42	117	2.1e-13	45.6	COG3255	Putative sterol carrier protein	134
2918278947	257	93.23	14	255	3	236	9.5e-85	278.6	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2918278948	255	96.51	1	255	6	254	4.9e-56	184.7	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2918278949	343	97.01	1	342	4	328	1.6e-41	137.3	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918278950	215	95.43	14	207	3	190	1.8e-74	244	COG0529	Adenylylsulfate kinase or related kinase	197
2918278951	241	80.22	6	238	36	250	1.0e-51	170.4	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
2918278952	185	85.78	1	182	4	184	3.7e-28	93	COG1648	Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain)	210
2918278953	273	97.13	12	260	3	239	3.7e-89	293.1	COG0007	Uroporphyrinogen-III methylase (siroheme synthase)	244
2918278955	562	99.22	12	558	2	511	0.0e+00	580	COG0155	Sulfite reductase, beta subunit (hemoprotein)	510
2918278956	165	95.81	1	164	6	165	1.2e-42	140.1	COG3749	Uncharacterized conserved protein, DUF934 family	167
2918278957	382	82.93	18	381	18	357	1.7e-26	85.8	COG1488	Nicotinic acid phosphoribosyltransferase	405
2918278958	161	88.68	7	161	16	156	2.0e-09	32	COG1580	Flagellar basal body-associated protein FliL	159
2918278959	450	99.56	2	446	2	454	0.0e+00	478.1	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
2918278960	299	98.92	1	289	1	275	3.0e-93	306.8	COG3546	Mn-containing catalase (includes spore coat protein CotJC)	277
2918278961	450	50.39	250	449	8	200	1.0e-11	7.2	COG0477	MFS family permease	338
2918278961	450	71.28	15	287	3	275	1.0e-11	35.8	COG0477	MFS family permease	338
2918278962	463	99.55	1	447	2	445	0.0e+00	751.6	COG3200	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase, class II	445
2918278964	153	89.94	7	153	16	158	2.3e-11	38.2	COG1580	Flagellar basal body-associated protein FliL	159
2918278965	497	98.54	22	494	2	473	0.0e+00	618.3	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918278966	540	80.2	15	398	76	391	1.2e-52	174.2	COG0642	Signal transduction histidine kinase	336
2918278966	540	92.48	408	535	6	128	6.4e-14	45.4	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918278967	297	98.6	12	292	2	282	1.6e-106	350.1	COG0414	Panthothenate synthetase	285
2918278968	49	21.03	1	49	100	140	2.8e-02	9.2	COG4709	Uncharacterized membrane protein	195
2918278971	218	84.38	91	218	20	127	8.7e-09	29.8	COG3794	Plastocyanin	128
2918278978	221	96.85	3	219	6	220	4.3e-57	188.2	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
2918278979	451	99.35	5	445	3	458	0.0e+00	548.3	COG1207	Bifunctional protein GlmU, N-acetylglucosamine-1-phosphate-uridyltransferase/glucosamine-1-phosphate-acetyltransferase	460
2918278980	608	100	1	608	1	615	0.0e+00	765.5	COG0449	Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains	597
2918278981	722	97.07	14	722	22	749	7.4e-130	428.7	COG4774	Outer membrane receptor for monomeric catechols	750
2918278982	196	90.81	15	196	15	182	1.4e-56	186	COG3108	Uncharacterized conserved protein YcbK, DUF882 family	185
2918278983	435	38.25	37	128	113	208	4.6e-79	78.3	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2918278983	435	42.23	138	268	109	214	4.6e-79	77	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2918278983	435	62.55	257	434	64	220	4.6e-79	113.4	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2918278984	149	95.57	1	148	6	156	1.0e-36	121.1	COG1522	DNA-binding transcriptional regulator, Lrp family	154
2918278985	207	98.08	2	207	3	206	5.2e-29	95.5	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
2918278987	326	90.28	1	323	8	295	1.8e-74	245.7	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
2918278989	328	88.41	7	325	32	359	2.3e-37	120.1	COG4188	Predicted dienelactone hydrolase	365
2918278990	83	17.46	50	75	34	44	5.9e-16	2.5	COG2906	Bacterioferritin-associated ferredoxin	63
2918278990	83	88.89	1	61	1	56	5.9e-16	51.8	COG2906	Bacterioferritin-associated ferredoxin	63
2918278992	575	67.26	154	570	128	392	1.3e-74	246.9	COG0642	Signal transduction histidine kinase	336
2918278993	210	95.54	11	210	6	198	2.5e-73	240.4	COG4566	Two-component response regulator, FixJ family, consists of REC and HTH domains	202
2918278994	652	53.81	219	651	277	601	6.7e-61	201.4	COG4191	Signal transduction histidine kinase regulating C4-dicarboxylate transport system	603
2918278995	337	98.8	1	332	2	329	1.7e-113	373.8	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
2918278996	230	85.88	1	180	8	159	1.8e-34	109.3	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
2918278997	432	99.74	47	430	1	378	0.0e+00	443.2	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
2918279002	878	59.21	372	746	43	341	2.3e-50	166.1	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
2918279002	878	97.05	4	302	10	305	3.8e-55	181.4	COG5309	Exo-beta-1,3-glucanase,  GH17 family	305
2918279003	82	8.03	2	66	327	357	3.1e-03	11	COG3853	Uncharacterized conserved protein YaaN involved in tellurite resistance	386
2918279004	68	13.99	2	68	189	235	2.6e-03	11.7	COG0470	DNA polymerase III, delta prime subunit	324
2918279005	238	97.63	6	231	3	208	2.5e-41	135.8	COG0177	Endonuclease III	211
2918279007	1091	33.26	584	804	30	191	3.1e-16	36.5	COG1061	Superfamily II DNA or RNA helicase	442
2918279007	1091	47.02	812	1073	184	412	3.1e-16	15.5	COG1061	Superfamily II DNA or RNA helicase	442
2918279008	215	66.81	2	176	59	213	2.5e-10	35.2	COG0671	Membrane-associated phospholipid phosphatase	232
2918279009	843	88.65	273	673	19	393	1.4e-51	170.2	COG2730	Aryl-phospho-beta-D-glucosidase BglC, GH1 family	407
2918279010	419	93.64	1	377	4	386	3.4e-12	41.5	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918279011	451	93.01	7	433	20	418	1.3e-18	58.8	COG3307	O-antigen ligase	424
2918279013	401	85.78	179	401	31	223	1.7e-71	234.3	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
2918279014	277	95.65	9	258	5	246	2.2e-35	116.3	COG1922	UDP-N-acetyl-D-mannosaminuronic acid transferase, WecB/TagA/CpsF family	253
2918279015	757	73.43	490	757	42	251	2.0e-39	128.9	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
2918279015	757	95.05	15	492	22	463	2.9e-69	227.8	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
2918279017	449	85.89	20	446	13	426	1.9e-44	146.4	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
2918279019	372	91.26	1	372	18	372	8.5e-55	177.5	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
2918279020	474	90.7	347	472	12	128	2.2e-41	135.3	COG0662	Mannose-6-phosphate isomerase, cupin superfamily	127
2918279020	474	99.4	4	337	2	334	5.0e-129	425	COG0836	Mannose-1-phosphate guanylyltransferase	333
2918279021	389	98.71	2	389	3	386	0.0e+00	556.7	COG0192	S-adenosylmethionine synthetase	388
2918279025	299	97.67	5	290	2	295	1.1e-56	187.4	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918279027	193	97.93	1	193	4	192	3.8e-64	210.5	COG2353	Polyisoprenoid-binding periplasmic protein YceI	192
2918279028	333	99.69	1	324	1	321	1.3e-125	413.4	COG0435	Glutathionyl-hydroquinone reductase	324
2918279029	257	99.25	10	255	2	267	1.1e-69	229.6	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918279031	291	59.14	13	287	22	186	5.1e-14	47.5	COG0500	SAM-dependent methyltransferase	257
2918279032	360	98.6	3	360	3	353	1.3e-79	262.4	COG3424	Predicted naringenin-chalcone synthase	356
2918279033	236	58.06	12	233	19	180	4.2e-08	28.4	COG0500	SAM-dependent methyltransferase	257
2918279034	369	77.4	3	331	3	317	9.9e-32	104.8	COG0644	Dehydrogenase (flavoprotein)	396
2918279035	119	77.42	1	115	20	115	6.4e-25	82.4	COG0599	Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family	124
2918279036	555	99.63	30	547	2	535	0.0e+00	584.9	COG4147	Na+(or H+)/acetate symporter ActP	529
2918279037	103	99.02	1	103	1	101	4.2e-29	95.2	COG3162	Uncharacterized membrane protein, DUF485 family	102
2918279038	793	81.98	281	662	68	390	4.7e-50	166.1	COG0642	Signal transduction histidine kinase	336
2918279039	241	98.71	5	236	2	230	9.9e-69	225.8	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918279040	542	96.13	14	541	12	557	5.9e-110	362.6	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2918279041	249	99.23	1	249	2	260	6.2e-92	302.1	COG2086	Electron transfer flavoprotein, alpha and beta subunits	260
2918279042	311	98.74	1	311	2	315	1.1e-106	351.7	COG2025	Electron transfer flavoprotein, alpha subunit	313
2918279043	596	97.49	17	460	7	395	5.3e-103	340	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918279046	629	11.44	24	137	62	100	0.0e+00	5.9	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
2918279046	629	98.83	83	628	5	341	0.0e+00	425.8	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
2918279047	638	83.56	2	541	2	499	0.0e+00	473.8	COG0358	DNA primase (bacterial type)	568
2918279048	152	99.32	1	150	2	148	1.8e-53	175.5	COG1610	Uncharacterized conserved protein YqeY	148
2918279049	391	98.11	13	389	4	367	0.0e+00	499.1	COG0505	Carbamoylphosphate synthase small subunit	368
2918279050	190	66.96	20	188	4	153	7.9e-33	108.1	COG2323	Uncharacterized membrane protein YcaP, DUF421 family	224
2918279053	1028	78.93	475	888	79	389	3.5e-47	156.7	COG0642	Signal transduction histidine kinase	336
2918279055	173	48.15	15	172	82	172	5.8e-15	50.4	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
2918279057	352	78.33	4	345	32	349	5.5e-32	102.7	COG5653	Acetyltransferase involved in cellulose biosynthesis, CelD/BcsL family	406
2918279058	351	54.77	5	345	184	407	6.4e-30	97.2	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918279059	282	87.8	19	248	6	221	4.7e-28	92.7	COG2120	N-acetylglucosaminyl deacetylase, LmbE family	237
2918279061	415	98.47	8	336	3	323	1.4e-107	353.9	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
2918279062	113	97.44	2	113	2	115	3.1e-33	109.1	COG1393	Arsenate reductase and related proteins, glutaredoxin family	117
2918279063	321	95.82	19	319	2	276	3.6e-64	211.2	COG2890	Methylase of polypeptide chain release factors	280
2918279064	707	76.4	163	573	89	389	2.2e-47	157.3	COG0642	Signal transduction histidine kinase	336
2918279065	196	71.6	17	179	42	157	3.3e-14	47.8	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2918279066	122	53.49	27	107	8	53	1.4e-04	16.1	COG3978	Acetolactate synthase small subunit, contains ACT domain	86
2918279067	298	94.94	30	272	9	233	7.1e-66	216.8	COG1183	Phosphatidylserine synthase	234
2918279068	232	89.53	1	221	25	255	6.6e-52	170.6	COG0688	Phosphatidylserine decarboxylase	239
2918279070	371	45.58	135	371	68	134	1.3e-04	15.6	COG1388	LysM repeat	124
2918279071	290	27.44	2	92	52	96	1.4e-22	19	COG2010	Cytochrome c, mono- and diheme variants	150
2918279071	290	99.39	109	286	1	163	1.4e-22	54.5	COG2010	Cytochrome c, mono- and diheme variants	150
2918279072	161	94.56	8	160	9	147	8.4e-23	75.8	COG3909	Cytochrome c556	147
2918279073	194	86.83	1	191	16	193	1.0e-60	199.4	COG1611	Predicted Rossmann fold nucleotide-binding protein	205
2918279074	407	96.57	1	400	15	408	0.0e+00	447.2	COG0538	Isocitrate dehydrogenase	407
2918279075	126	8.9	2	50	16	54	2.0e-07	11.4	COG4091	Predicted homoserine dehydrogenase, contains C-terminal SAF domain	438
2918279075	126	9.36	39	113	80	120	2.0e-07	12.8	COG4091	Predicted homoserine dehydrogenase, contains C-terminal SAF domain	438
2918279076	202	91.39	2	201	9	199	2.4e-37	122.8	COG3932	Uncharacterized conserved protein	209
2918279077	122	30.77	1	59	1	52	9.0e-46	79.7	COG5352	Uncharacterized protein	169
2918279077	122	33.14	51	117	112	167	9.0e-46	72	COG5352	Uncharacterized protein	169
2918279078	263	98.44	7	261	4	256	3.0e-57	188.9	COG5662	Transmembrane transcriptional regulator (anti-sigma factor RsiW)	256
2918279079	177	88.71	7	172	17	181	9.2e-49	160.1	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918279080	481	98.56	2	344	3	345	8.1e-107	351.7	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
2918279081	417	95.01	1	415	12	411	9.8e-49	161	COG2124	Cytochrome P450	411
2918279085	83	42.31	3	79	9	63	8.5e-08	28	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918279087	657	21.89	4	91	22	72	5.9e-11	14	COG3910	Predicted ATPase	233
2918279087	657	24.46	317	419	135	191	5.9e-11	20.5	COG3910	Predicted ATPase	233
2918279096	261	83.33	7	260	46	275	4.8e-62	204	COG4760	Uncharacterized membrane protein, YccA/Bax inhibitor family	276
2918279098	397	99.75	1	397	1	392	0.0e+00	625.6	COG3825	Uncharacterized conserved protein,  contains von Willebrand factor type A (vWA) domain	393
2918279099	186	18.23	2	173	28	159	3.4e-28	92.9	COG0317	(p)ppGpp synthase/hydrolase, HD superfamily	701
2918279102	229	33.4	54	227	4	166	4.4e-49	162.6	COG3119	Arylsulfatase A or related enzyme	475
2918279103	270	75.08	1	266	80	329	6.0e-57	185.3	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
2918279107	346	91.48	22	333	16	294	2.2e-47	156.3	COG4313	Uncharacterized conserved protein	304
2918279108	337	53.6	65	221	5	123	5.9e-05	17.1	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
2918279109	327	96.67	1	327	10	328	6.1e-96	316	COG0714	MoxR-like ATPase	329
2918279110	337	60.19	19	320	164	414	6.7e-44	145	COG1721	Uncharacterized conserved protein, DUF58 family, contains vWF domain	416
2918279112	345	54.74	76	278	83	232	2.3e-12	39.7	COG1240	Mg-chelatase subunit ChlD	261
2918279114	222	36.41	14	214	24	157	5.2e-07	24.6	COG0457	Tetratricopeptide (TPR) repeat	291
2918279117	141	34.6	1	140	258	394	2.6e-46	152.8	COG3328	Transposase (or an inactivated derivative)	379
2918279118	344	80.22	108	344	20	234	3.5e-47	155.3	COG1018	Ferredoxin-NADP reductase	266
2918279118	344	91.26	3	100	2	95	1.4e-12	39.8	COG0633	Ferredoxin	102
2918279119	555	96.88	1	555	4	562	0.0e+00	570.2	COG1151	Hydroxylamine reductase (hybrid-cluster protein)	576
2918279121	1043	63.78	314	1038	326	899	0.0e+00	564.5	COG0553	Superfamily II DNA or RNA helicase, SNF2 family	866
2918279122	271	63.47	18	263	2	173	1.9e-75	248.6	COG4279	Uncharacterized conserved protein, contains Zn finger domain	266
2918279123	887	92.48	1	445	35	477	4.7e-77	253.7	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918279123	887	100	451	858	1	379	0.0e+00	454	COG1454	Alcohol dehydrogenase, class IV	377
2918279124	278	98.23	1	276	5	281	7.4e-86	282.3	COG1737	DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains	281
2918279125	209	98.08	1	208	1	204	2.5e-52	172.1	COG0288	Carbonic anhydrase	207
2918279126	174	98.76	10	166	1	159	2.7e-59	193.8	COG3265	Gluconate kinase	161
2918279127	608	98.62	5	608	4	573	0.0e+00	645.5	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
2918279128	471	98.31	5	471	4	469	0.0e+00	583.1	COG0362	6-phosphogluconate dehydrogenase	473
2918279129	453	97.54	14	453	7	442	0.0e+00	480.8	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
2918279130	309	96.68	14	307	2	292	1.4e-41	137.6	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918279131	420	98.33	12	413	4	414	3.7e-61	201.8	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
2918279132	333	98.77	10	326	1	321	3.5e-124	408.6	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
2918279133	340	96.56	17	324	2	310	1.4e-108	357.5	COG4608	ABC-type oligopeptide transport system, ATPase component	309
2918279134	297	90.27	6	297	25	293	5.5e-84	276.2	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2918279135	317	99.37	1	317	1	316	1.9e-104	344.1	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2918279136	539	94.98	2	538	15	563	3.4e-90	298	COG0747	ABC-type transport system, periplasmic component	556
2918279137	398	84.41	12	397	68	473	1.0e-81	269.6	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
2918279138	548	91.36	3	531	9	537	9.5e-53	173.9	COG3653	N-acyl-D-aspartate/D-glutamate deacylase	579
2918279139	417	97.85	12	417	9	417	6.1e-51	168.3	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
2918279140	408	90.46	29	408	19	331	6.3e-70	230.4	COG1171	Threonine dehydratase	347
2918279141	296	96.81	11	288	5	277	5.0e-57	187.6	COG1737	DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains	281
2918279142	245	92.42	5	245	17	260	9.4e-32	103.9	COG3971	2-keto-4-pentenoate hydratase	264
2918279143	349	98.8	13	342	2	331	2.4e-107	353.5	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
2918279144	312	99.39	1	312	1	325	4.9e-95	312.7	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
2918279145	262	99.17	20	260	2	241	9.6e-117	382.9	COG1126	ABC-type polar amino acid transport system, ATPase component	240
2918279146	270	93.99	5	269	11	276	1.1e-59	196.5	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918279147	217	92.54	1	216	17	227	1.4e-73	242	COG0765	ABC-type amino acid transport system, permease component	222
2918279148	224	91.67	2	220	15	223	3.3e-70	230.8	COG0765	ABC-type amino acid transport system, permease component	222
2918279149	225	80.86	1	223	10	216	1.1e-47	156.9	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
2918279150	486	31.69	294	483	354	520	1.2e-23	55.2	COG1620	L-lactate permease	522
2918279150	486	44.21	1	246	6	238	1.2e-23	29.1	COG1620	L-lactate permease	522
2918279151	227	92.24	3	224	13	226	1.1e-56	186.4	COG1802	DNA-binding transcriptional regulator, GntR family	230
2918279152	345	90.45	4	342	9	311	3.4e-76	250.6	COG2334	Ser/Thr protein kinase RdoA involved in Cpx stress response, MazF antagonist	331
2918279153	438	96.41	5	438	15	444	0.0e+00	450.7	COG0160	4-aminobutyrate aminotransferase or related aminotransferase	447
2918279154	296	98.08	6	296	3	309	1.8e-46	153.1	COG0679	Predicted permease	311
2918279155	235	41.64	12	216	84	235	1.8e-14	47.8	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
2918279156	165	20.66	2	133	49	136	5.5e-05	17	COG4942	Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB	420
2918279157	238	17.02	41	236	418	528	4.0e-07	23.1	COG2433	Possible nuclease of RNase H fold, RuvC/YqgF family	652
2918279158	518	57.96	65	312	139	331	2.8e-18	60.5	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
2918279160	239	90.27	4	231	6	209	3.0e-55	181.4	COG1136	ABC-type lipoprotein export system, ATPase component	226
2918279163	888	98.9	5	884	7	818	0.0e+00	595.5	COG4458	Uncharacterized protein	821
2918279164	999	99.9	1	998	1	1013	0.0e+00	1005.7	COG4457	Uncharacterized protein	1014
2918279166	595	17.88	80	195	52	100	1.9e-03	6.8	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
2918279166	595	38.32	240	411	63	167	1.9e-03	11.8	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
2918279168	649	98.88	3	629	2	621	0.0e+00	841.8	COG1154	Deoxyxylulose-5-phosphate synthase	627
2918279171	238	94.5	3	206	12	217	2.6e-18	60.7	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2918279174	331	98.24	1	331	4	338	7.8e-95	312.3	COG1064	D-arabinose 1-dehydrogenase, Zn-dependent alcohol dehydrogenase family	339
2918279177	108	62.2	3	108	40	141	1.9e-10	35.7	COG2010	Cytochrome c, mono- and diheme variants	150
2918279178	117	57.93	4	117	51	145	2.7e-08	28.6	COG2010	Cytochrome c, mono- and diheme variants	150
2918279179	231	87.16	3	205	28	217	3.7e-38	125.7	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2918279180	185	51.32	26	175	68	164	1.2e-15	52.3	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
2918279181	188	95.91	1	188	1	164	1.5e-44	146.9	COG4675	Microcystin-dependent protein  (function unknown)	170
2918279182	182	99.42	2	182	1	170	9.3e-60	196.3	COG4675	Microcystin-dependent protein  (function unknown)	170
2918279183	183	99.42	2	183	1	170	1.5e-54	179.4	COG4675	Microcystin-dependent protein  (function unknown)	170
2918279189	598	94.26	16	586	14	571	4.4e-109	360.1	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
2918279191	330	98.44	1	321	2	317	7.5e-65	214.1	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2918279192	484	96.33	20	474	10	429	2.9e-69	228.1	COG0677	UDP-N-acetyl-D-mannosaminuronate dehydrogenase	436
2918279193	411	91.69	1	409	25	399	1.5e-27	91.9	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918279194	387	98.4	11	382	5	373	9.4e-116	381.5	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
2918279195	539	17.89	325	405	117	150	5.7e-25	23.1	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
2918279195	539	50	398	501	81	175	5.7e-25	64.4	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
2918279195	539	98.58	10	334	5	350	2.4e-68	225.4	COG0673	Predicted dehydrogenase	342
2918279196	479	96.56	41	476	5	425	0.0e+00	535.4	COG0677	UDP-N-acetyl-D-mannosaminuronate dehydrogenase	436
2918279197	236	84	1	213	31	219	3.5e-61	200.8	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
2918279198	377	98.13	1	371	6	373	7.1e-119	391.8	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
2918279199	239	63.76	1	237	2	242	4.7e-73	240.7	COG1208	NDP-sugar pyrophosphorylase, includes eIF-2Bgamma, eIF-2Bepsilon, and LPS biosynthesis proteins	358
2918279200	756	76.92	478	756	44	263	6.3e-39	127.9	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
2918279200	756	95.48	29	500	21	464	2.7e-66	218.3	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
2918279201	610	90.88	1	586	1	498	1.2e-127	421.1	COG0367	Asparagine synthetase B (glutamine-hydrolyzing)	542
2918279202	410	91.44	30	389	32	405	9.3e-27	88.3	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918279203	452	75.76	11	426	57	381	3.8e-16	53.2	COG3307	O-antigen ligase	424
2918279204	241	70.97	1	234	28	225	1.2e-10	36.7	COG0500	SAM-dependent methyltransferase	257
2918279205	452	85.06	16	436	5	414	3.4e-27	89.5	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
2918279214	391	78.55	8	372	13	338	1.2e-47	157.2	COG3919	Predicted ATP-dependent carboligase, ATP-grasp superfamily	415
2918279217	278	96.68	50	277	2	205	3.0e-47	155.4	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918279218	171	58.77	40	171	2	125	1.3e-14	48.8	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918279220	244	98.58	17	235	2	209	3.4e-44	145.4	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918279221	505	96.62	20	502	16	473	4.4e-106	349.8	COG0246	Mannitol-1-phosphate/altronate dehydrogenases	473
2918279222	212	93.36	5	211	12	208	1.0e-69	228.6	COG0800	2-keto-3-deoxy-6-phosphogluconate aldolase	211
2918279223	253	91.38	15	240	10	221	3.4e-61	201	COG1802	DNA-binding transcriptional regulator, GntR family	230
2918279224	325	97.15	17	322	1	307	2.0e-65	215.4	COG0524	Sugar or nucleoside kinase, ribokinase family	311
2918279225	315	97.34	26	310	6	298	8.6e-51	167.4	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918279226	507	14.07	8	98	175	230	0.0e+00	9.3	COG2721	Altronate dehydratase	381
2918279226	507	99.75	103	507	2	398	0.0e+00	537.7	COG2721	Altronate dehydratase	381
2918279227	466	99.14	1	466	3	462	0.0e+00	625.7	COG1904	Glucuronate isomerase	463
2918279228	257	93.1	23	250	8	223	4.5e-61	200.6	COG1802	DNA-binding transcriptional regulator, GntR family	230
2918279229	219	85.59	4	212	5	194	5.0e-26	86.5	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
2918279230	135	45.45	37	100	8	47	3.0e-06	20.7	COG1873	Sporulation protein YlmC, PRC-barrel domain family	87
2918279231	252	98.11	1	252	2	260	1.4e-38	126.8	COG3971	2-keto-4-pentenoate hydratase	264
2918279233	226	78.52	1	225	17	217	2.5e-49	162.4	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
2918279235	300	97.36	22	299	5	262	3.0e-73	240.5	COG2116	Formate/nitrite transporter FocA, FNT family	265
2918279236	260	95.56	16	260	4	240	1.5e-70	231.8	COG1180	Pyruvate-formate lyase-activating enzyme	260
2918279237	515	99.16	7	476	3	476	0.0e+00	582.5	COG0469	Pyruvate kinase	477
2918279238	253	92.67	17	242	8	222	1.6e-63	208.7	COG1802	DNA-binding transcriptional regulator, GntR family	230
2918279239	278	99.64	3	278	2	278	0.0e+00	445.5	COG3717	5-keto 4-deoxyuronate isomerase	278
2918279240	254	99.25	7	253	2	267	3.1e-71	234.7	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918279241	116	85.5	4	116	14	125	2.1e-19	64.3	COG1917	Cupin domain protein related to quercetin dioxygenase	131
2918279243	404	98.49	5	393	3	394	0.0e+00	445.9	COG0282	Acetate kinase	396
2918279244	481	16.51	185	251	20	73	3.1e-67	15.3	COG0280	Phosphotransacetylase	327
2918279244	481	67.58	243	471	105	325	3.1e-67	204.9	COG0280	Phosphotransacetylase	327
2918279244	481	93.71	7	155	9	157	1.9e-31	102.2	COG2030	Acyl dehydratase	159
2918279245	760	99.21	11	759	6	754	0.0e+00	1047.1	COG1882	Pyruvate-formate lyase	755
2918279246	278	97.87	1	276	5	280	2.2e-86	284	COG1737	DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains	281
2918279247	649	90.38	12	643	15	634	4.4e-53	174.9	COG1289	Uncharacterized membrane protein YccC	674
2918279248	156	93.98	15	147	5	129	1.1e-22	75.1	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918279249	339	99.12	1	338	2	339	2.6e-112	369.6	COG1064	D-arabinose 1-dehydrogenase, Zn-dependent alcohol dehydrogenase family	339
2918279250	133	88.82	1	133	13	147	3.9e-24	79.8	COG0054	6,7-dimethyl-8-ribityllumazine synthase (Riboflavin synthase beta chain)	152
2918279251	216	96.59	1	211	4	201	1.7e-48	159.2	COG2095	Small neutral amino acid transporter SnatA, MarC family	203
2918279253	407	47.9	35	399	351	703	3.2e-24	75.9	COG0507	ATP-dependent exoDNAse (exonuclease V), alpha subunit, helicase superfamily I	696
2918279254	357	98.72	10	357	3	311	3.1e-71	234.8	COG2017	Galactose mutarotase or related enzyme	308
2918279255	234	91.38	2	223	12	223	1.1e-60	199.4	COG1802	DNA-binding transcriptional regulator, GntR family	230
2918279256	144	87.32	1	141	3	126	1.6e-53	174.9	COG1803	Methylglyoxal synthase	142
2918279257	329	96.39	1	329	10	329	1.9e-108	357.3	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
2918279258	179	88.7	15	177	4	160	8.2e-37	120.8	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
2918279259	427	99.47	46	427	1	377	1.3e-124	410.4	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
2918279261	328	98.45	7	328	3	319	1.9e-107	353.6	COG2358	TRAP-type uncharacterized transport system, periplasmic component	321
2918279262	694	98.93	28	694	2	650	0.0e+00	754.7	COG4666	TRAP-type uncharacterized transport system, fused permease components	642
2918279263	338	87.91	9	331	31	328	1.1e-93	308.2	COG3367	Uncharacterized conserved protein, NAD-dependent epimerase/dehydratase family	339
2918279264	158	98.09	1	157	1	154	8.4e-70	228.3	COG2193	Bacterioferritin (cytochrome b1)	157
2918279265	179	36.75	15	167	6	48	9.8e-03	9.6	COG2963	Transposase and inactivated derivatives	116
2918279267	457	73.32	6	407	6	332	8.4e-49	160.9	COG3522	Predicted component of the type VI protein secretion system	446
2918279268	281	65.53	55	274	89	261	3.1e-23	77.1	COG3455	Type VI protein secretion system component VasF	262
2918279270	374	92.92	10	363	10	337	1.1e-38	121.4	COG3515	Predicted component of the type VI protein secretion system	346
2918279271	177	95.86	2	170	2	163	4.4e-61	199.8	COG3516	Predicted component of the type VI protein secretion system	169
2918279272	495	98.99	1	495	4	493	0.0e+00	712.7	COG3517	Predicted component of the type VI protein secretion system	495
2918279273	166	91.77	1	162	1	145	8.7e-35	114.5	COG3157	Type VI protein secretion system component Hcp (secreted cytotoxin)	162
2918279274	159	78.98	10	155	21	144	3.5e-17	56.8	COG3518	Predicted component of the type VI protein secretion system	157
2918279275	604	99.68	6	604	3	621	0.0e+00	577	COG3519	Type VI protein secretion system component VasA	621
2918279276	381	5.67	339	373	304	322	3.9e-83	7.2	COG3520	Predicted component of the type VI protein secretion system	335
2918279276	381	90.75	1	332	10	313	3.9e-83	269	COG3520	Predicted component of the type VI protein secretion system	335
2918279279	885	98.39	10	876	1	792	0.0e+00	920.8	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
2918279280	673	98.96	2	564	6	577	0.0e+00	538.2	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
2918279281	207	23.18	115	185	120	173	1.1e-24	29	COG2849	Antitoxin component YwqK of the YwqJK toxin-antitoxin module	230
2918279281	207	56.65	10	147	89	220	1.1e-24	58	COG2849	Antitoxin component YwqK of the YwqJK toxin-antitoxin module	230
2918279285	276	86.22	80	274	8	176	3.8e-77	252.2	COG1045	Serine acetyltransferase	194
2918279286	287	98.25	5	277	1	280	8.4e-83	272.3	COG2301	Citrate lyase beta subunit	283
2918279287	278	98.9	1	277	1	270	1.3e-81	268.4	COG3777	Hydroxyacyl-ACP dehydratase HTD2, hotdog domain	273
2918279288	375	94.51	1	374	7	385	5.7e-120	395.4	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2918279289	386	97.49	2	386	9	397	6.6e-107	352.6	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918279290	303	98.34	1	297	1	296	2.5e-61	202.6	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918279292	310	89.01	39	309	10	260	4.3e-45	148.2	COG0656	Aldo/keto reductase, related to diketogulonate reductase	280
2918279293	152	94.74	21	146	3	128	8.9e-28	91.6	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918279294	140	97.2	1	140	4	142	1.4e-51	169.1	COG1764	Organic hydroperoxide reductase OsmC/OhrA	143
2918279295	382	93.92	1	382	13	383	9.2e-37	121.1	COG2814	Predicted arabinose efflux permease, MFS family	394
2918279296	848	92.14	32	840	57	841	0.0e+00	493.4	COG3264	Small-conductance mechanosensitive channel	835
2918279301	156	61.89	6	156	104	280	8.0e-29	95.7	COG1652	Nucleoid-associated protein YgaU, contains BON and LysM domains	269
2918279302	982	26.4	192	374	56	159	2.0e-60	9	COG0642	Signal transduction histidine kinase	336
2918279302	982	74.37	449	841	100	392	2.0e-60	199.9	COG0642	Signal transduction histidine kinase	336
2918279302	982	90.98	855	982	8	128	4.8e-16	52.4	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918279303	474	95.72	16	456	15	417	1.7e-79	262.1	COG2124	Cytochrome P450	411
2918279304	342	55.3	205	334	53	125	5.8e-06	20.2	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918279305	201	79.75	1	188	1	189	4.2e-41	136	COG3416	Uncharacterized protein	233
2918279306	75	73.4	1	75	3	71	1.1e-17	59	COG1826	Sec-independent protein translocase protein TatA	94
2918279308	299	92.41	3	290	16	295	3.1e-55	181.8	COG1295	Uncharacterized membrane protein, BrkB/YihY/UPF0761 family (not an RNase)	303
2918279309	549	77.41	77	540	88	392	2.3e-41	136.7	COG0642	Signal transduction histidine kinase	336
2918279310	558	67.77	189	551	124	390	3.3e-49	162.6	COG0642	Signal transduction histidine kinase	336
2918279311	130	90.98	2	130	8	128	1.0e-26	88	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918279312	102	98.81	13	102	2	84	2.0e-07	26.1	COG1977	Molybdopterin converting factor, small subunit	84
2918279313	465	88.48	1	240	3	217	3.3e-70	230	COG3482	Uncharacterized protein	237
2918279314	440	95.51	21	416	9	391	6.4e-77	253.1	COG1944	Ribosomal protein S12 methylthiotransferase accessory factor YcaO	398
2918279316	564	80.74	316	562	37	233	6.6e-42	138.3	COG2114	Adenylate cyclase, class 3	227
2918279320	143	99.39	2	133	1	162	2.2e-24	80.9	COG0517	CBS domain	117
2918279321	195	55.11	21	183	95	218	1.1e-19	65.1	COG2979	Uncharacterized membrane protein YebE, DUF533 family	225
2918279322	588	98.76	15	588	4	480	1.0e-97	322.1	COG0471	Di- and tricarboxylate transporter	461
2918279324	111	41.9	22	99	32	75	5.3e-06	21.4	COG4323	Uncharacterized protein	105
2918279325	158	89.38	7	158	9	151	5.8e-52	170.2	COG4329	Uncharacterized membrane protein	160
2918279326	47	13.2	1	47	101	140	7.0e-04	13.5	COG1575	1,4-dihydroxy-2-naphthoate octaprenyltransferase	303
2918279328	487	79.34	19	467	6	439	0.0e+00	444.7	COG0595	mRNA degradation ribonuclease J1/J2	555
2918279329	484	98.12	5	482	2	471	0.0e+00	527.1	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918279330	451	97.69	15	442	8	388	1.2e-34	114.5	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918279331	583	96.9	1	574	12	573	0.0e+00	662.7	COG4618	ABC-type protease/lipase transport system, ATPase and permease components	580
2918279334	141	49.57	1	125	2	116	8.8e-16	52.4	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918279337	175	91.18	37	174	11	134	4.3e-22	73.2	COG4520	Surface antigen	136
2918279339	93	91.92	1	92	8	98	1.0e-23	78.1	COG2388	Predicted acetyltransferase, GNAT superfamily	99
2918279340	277	97.2	12	277	1	243	4.9e-31	102.4	COG1587	Uroporphyrinogen-III synthase	248
2918279341	150	88.67	1	148	2	134	3.7e-44	144.9	COG1959	DNA-binding transcriptional regulator, IscR family	150
2918279342	409	96.17	5	407	10	411	1.4e-73	242.8	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
2918279343	408	94.74	6	406	20	415	1.3e-48	160.2	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
2918279344	160	90.34	1	160	14	172	5.7e-73	239.2	COG3195	2-oxo-4-hydroxy-4-carboxy--5-ureidoimidazoline (OHCU) decarboxylase	176
2918279345	125	95.16	1	125	7	124	3.9e-50	163.7	COG2351	5-hydroxyisourate hydrolase (purine catabolism), transthyretin-related family	124
2918279346	395	98.77	1	394	1	403	0.0e+00	565.8	COG3748	Uncharacterized membrane protein	407
2918279347	306	98.34	3	299	3	298	7.2e-71	233.9	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918279348	267	89.57	1	256	3	251	4.6e-63	207.4	COG0388	Predicted amidohydrolase	274
2918279349	349	97.09	42	343	6	305	1.3e-85	281.8	COG0010	Arginase family enzyme	305
2918279350	266	91.39	1	254	12	255	3.2e-66	217.8	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
2918279351	284	93.75	3	284	13	282	2.2e-60	199	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
2918279352	355	97.45	1	350	4	347	4.8e-117	385.6	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
2918279353	372	94.44	10	371	6	362	2.1e-55	182.7	COG0687	Spermidine/putrescine-binding periplasmic protein	363
2918279354	307	98.34	9	304	2	297	4.7e-51	168.8	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918279355	489	97.98	31	472	2	390	2.1e-107	353.9	COG0348	Polyferredoxin	386
2918279356	472	98.46	15	465	3	451	2.6e-101	334.1	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
2918279357	462	90.35	123	462	18	223	4.6e-50	164.1	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
2918279359	356	99.1	20	355	2	332	1.1e-91	302.2	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
2918279360	887	19.07	1	162	63	181	2.0e-97	6.5	COG3914	Predicted O-linked N-acetylglucosamine transferase, SPINDLY family	620
2918279360	887	79.49	288	874	125	620	2.0e-97	307.3	COG3914	Predicted O-linked N-acetylglucosamine transferase, SPINDLY family	620
2918279361	369	98.82	11	366	2	337	4.2e-34	112.5	COG0859	ADP-heptose:LPS heptosyltransferase	334
2918279365	608	81.48	534	607	12	77	1.4e-08	28.7	COG0236	Acyl carrier protein	80
2918279365	608	92.25	13	527	32	555	5.9e-86	283.3	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2918279366	582	14.86	100	198	39	120	2.4e-71	36.6	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
2918279366	582	65.22	212	580	179	538	2.4e-71	196.7	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
2918279368	387	89.72	1	386	15	398	6.4e-61	200.9	COG1696	D-alanyl-lipoteichoic acid acyltransferase DltB, MBOAT superfamily	425
2918279369	253	98.88	1	249	1	265	7.1e-57	187.6	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918279370	548	99.75	8	459	2	407	0.0e+00	438.5	COG0644	Dehydrogenase (flavoprotein)	396
2918279371	277	76.73	1	142	6	127	1.5e-14	12.7	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2918279371	277	87.42	137	277	18	156	1.5e-14	36.6	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2918279372	299	68.52	5	299	2	284	6.7e-68	224.2	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
2918279373	668	99.69	1	664	1	644	0.0e+00	895.8	COG4770	Acetyl/propionyl-CoA carboxylase, alpha subunit	645
2918279374	260	97.74	1	258	7	265	1.3e-69	229.2	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918279375	535	99.62	12	535	2	525	0.0e+00	687.3	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component	526
2918279376	377	97.74	1	377	4	393	0.0e+00	470.9	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918279377	393	99.24	2	393	3	393	1.9e-125	413.5	COG0183	Acetyl-CoA acetyltransferase	392
2918279378	390	98.75	9	390	2	395	0.0e+00	448.4	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918279379	497	99.16	20	497	2	476	0.0e+00	528.7	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918279380	409	94.29	2	405	11	423	6.3e-54	175.2	COG1541	Phenylacetate-coenzyme A ligase PaaK, adenylate-forming domain family	438
2918279381	280	99.16	19	259	2	236	8.1e-91	297.8	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2918279382	426	96.17	13	402	4	355	7.7e-22	72.2	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918279383	357	95.98	24	349	10	319	2.2e-78	258.3	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918279384	295	98.67	1	294	2	298	3.6e-66	218.3	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2918279385	643	97.72	1	604	12	610	0.0e+00	466.1	COG1022	Long-chain acyl-CoA synthetase (AMP-forming)	613
2918279386	273	99.21	4	258	3	254	8.1e-97	318	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2918279387	296	99.65	2	293	2	286	1.9e-106	350	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
2918279388	379	98.75	1	379	1	394	0.0e+00	460.1	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918279389	254	90.95	26	246	8	218	2.5e-57	188.3	COG1802	DNA-binding transcriptional regulator, GntR family	230
2918279390	517	97.18	1	515	8	559	5.2e-126	415.8	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2918279391	249	98.85	1	249	1	258	8.8e-94	308.1	COG2086	Electron transfer flavoprotein, alpha and beta subunits	260
2918279392	313	99.69	1	312	1	317	1.0e-114	378.1	COG2025	Electron transfer flavoprotein, alpha subunit	313
2918279393	175	95.04	11	151	5	138	9.6e-20	65.1	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
2918279394	187	80.86	1	182	15	183	1.4e-17	59.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918279402	133	87.16	1	133	10	138	4.8e-53	173.7	COG4957	Predicted transcriptional regulator	148
2918279403	159	51.03	5	155	47	145	2.6e-04	14.7	COG1525	Endonuclease YncB, thermonuclease family	192
2918279406	133	22.97	1	47	93	126	3.5e-05	7.4	COG4103	Uncharacterized conserved protein, tellurite resistance protein B (TerB) family	148
2918279406	133	29.73	53	128	27	70	3.5e-05	9.8	COG4103	Uncharacterized conserved protein, tellurite resistance protein B (TerB) family	148
2918279407	362	35.48	239	360	65	119	8.4e-10	32.1	COG1403	5-methylcytosine-specific restriction endonuclease McrA	146
2918279408	414	5.67	353	412	364	394	7.4e-33	9	COG0595	mRNA degradation ribonuclease J1/J2	555
2918279408	414	46.98	1	257	9	265	7.4e-33	96.4	COG0595	mRNA degradation ribonuclease J1/J2	555
2918279411	201	51.76	3	198	141	302	4.2e-11	37.4	COG2378	Predicted DNA-binding transcriptional regulator YafY, contains an HTH and WYL domains	311
2918279413	94	77.78	1	93	1	91	1.4e-15	52.3	COG2963	Transposase and inactivated derivatives	116
2918279414	277	85.92	43	272	29	272	2.4e-46	152.8	COG2801	Transposase InsO and inactivated derivatives	232
2918279415	67	67.14	2	64	16	62	4.2e-04	14.5	COG3311	Predicted DNA-binding transcriptional regulator AlpA	70
2918279420	270	95.42	4	247	5	275	9.4e-43	141.1	COG2801	Transposase InsO and inactivated derivatives	232
2918279425	109	66.67	1	92	17	84	1.4e-09	31.6	COG4321	Predicted DNA-binding protein, contains Ribbon-helix-helix (RHH) domain	102
2918279426	261	88.93	1	261	31	295	3.4e-73	240.8	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2918279427	312	99.06	1	309	1	315	2.1e-72	238.8	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2918279428	536	95.85	6	530	11	564	1.9e-81	269.1	COG0747	ABC-type transport system, periplasmic component	556
2918279429	152	70.59	12	127	15	86	1.8e-15	50.4	COG4321	Predicted DNA-binding protein, contains Ribbon-helix-helix (RHH) domain	102
2918279431	348	75	274	340	18	77	1.6e-12	40.8	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2918279432	150	52.31	19	144	2	69	2.8e-14	48.5	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918279437	408	75.46	10	132	41	163	1.1e-31	103.9	COG3436	Transposase	157
2918279438	136	53.85	10	109	2	64	4.6e-16	53.8	COG2963	Transposase and inactivated derivatives	116
2918279439	65	36.2	1	63	29	87	2.2e-11	37.8	COG3436	Transposase	157
2918279440	696	81.42	12	211	3	186	5.1e-30	98.7	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
2918279441	62	33.74	1	62	84	138	4.7e-10	34.1	COG3436	Transposase	157
2918279442	520	98.16	107	268	4	163	2.3e-40	132.6	COG3436	Transposase	157
2918279443	132	54.7	3	87	4	67	6.1e-17	56.4	COG2963	Transposase and inactivated derivatives	116
2918279444	115	66.26	1	114	29	136	4.1e-29	95.9	COG3436	Transposase	157
2918279445	541	96.93	103	265	6	163	6.6e-41	134.4	COG3436	Transposase	157
2918279446	1098	80.2	173	827	2	633	9.4e-81	265.9	COG1483	Predicted ATPase, AAA+ superfamily	774
2918279447	986	98.69	7	980	2	904	0.0e+00	462.2	COG1743	Adenine-specific DNA methylase, contains a Zn-ribbon domain	875
2918279449	1167	24.85	486	694	284	404	1.6e-21	22.3	COG1061	Superfamily II DNA or RNA helicase	442
2918279449	1167	28.95	104	353	58	198	1.6e-21	48.1	COG1061	Superfamily II DNA or RNA helicase	442
2918279451	71	17.32	1	70	337	407	8.6e-16	52.6	COG3464	Transposase	402
2918279457	383	94.93	70	376	16	333	3.7e-38	126.2	COG0582	Integrase	309
2918279458	555	75.82	206	543	57	310	1.8e-17	57.6	COG0582	Integrase	309
2918279459	71	25.58	10	59	93	125	1.2e-03	12.6	COG3677	Transposase	129
2918279461	208	92.04	8	207	1	208	2.3e-50	165.9	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
2918279466	194	19.65	1	184	58	170	6.5e-05	16.7	COG2989	Murein L,D-transpeptidase YcbB/YkuD	561
2918279471	229	72.2	1	228	5	230	3.7e-77	254.4	COG2378	Predicted DNA-binding transcriptional regulator YafY, contains an HTH and WYL domains	311
2918279472	123	89.76	1	122	13	126	1.3e-07	26.5	COG3324	Predicted enzyme related to lactoylglutathione lyase	127
2918279478	350	96.23	1	264	6	260	7.5e-65	213.2	COG0300	Short-chain dehydrogenase	265
2918279479	78	91.25	1	75	7	79	1.5e-22	74	COG0425	TusA-related sulfurtransferase	78
2918279480	416	67.6	186	407	72	240	1.0e-21	70.8	COG2014	Uncharacterized conserved protein, contains DUF4213 and DUF364 domains	250
2918279481	108	91.35	1	99	8	102	1.9e-47	154.4	COG3492	Uncharacterized protein	104
2918279483	418	98.03	6	416	6	404	0.0e+00	447.7	COG0303	Molybdopterin biosynthesis enzyme	404
2918279485	349	69.47	50	349	20	292	6.6e-98	323.2	COG1686	D-alanyl-D-alanine carboxypeptidase	389
2918279486	89	74.32	2	86	6	60	6.2e-15	49.7	COG3313	Predicted Fe-S protein YdhL, DUF1289 family	74
2918279489	277	94.37	1	277	7	291	1.1e-102	337.8	COG3285	Eukaryotic-type DNA primase	299
2918279490	411	95.56	13	399	8	373	7.1e-31	97.8	COG0477	MFS family permease	338
2918279491	423	77.55	72	404	44	195	6.1e-41	134.9	COG0807	GTP cyclohydrolase II	193
2918279493	211	98.1	4	211	4	209	1.6e-83	274	COG0035	Uracil phosphoribosyltransferase	210
2918279494	348	77.27	199	332	24	125	3.1e-23	75.7	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918279495	1155	87.14	176	1145	5	492	7.9e-24	45.8	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918279496	420	92.62	17	392	4	342	1.5e-38	127.2	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918279497	230	87.2	12	229	25	208	2.7e-59	194.5	COG0177	Endonuclease III	211
2918279498	80	42.96	1	79	1	61	2.9e-18	61.3	COG5319	Uncharacterized protein	142
2918279499	308	27.31	8	253	58	122	1.9e-02	7.3	COG3409	Peptidoglycan-binding (PGRP) domain of peptidoglycan hydrolases	185
2918279500	234	97.45	1	234	1	229	7.4e-58	190.4	COG4778	Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL	235
2918279503	196	98.43	1	196	1	188	6.2e-40	131.7	COG2249	Putative NADPH-quinone reductase (modulator of drug activity B)	189
2918279504	482	98.49	36	481	3	458	4.5e-129	425.6	COG2723	Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase	460
2918279508	64	17.61	30	64	8	35	1.5e-03	8.2	COG1580	Flagellar basal body-associated protein FliL	159
2918279508	64	23.27	1	43	16	52	1.5e-03	9.1	COG1580	Flagellar basal body-associated protein FliL	159
2918279509	189	99.46	1	189	1	184	1.2e-71	234.7	COG2096	Cob(I)alamin adenosyltransferase	184
2918279510	249	98.85	1	249	1	258	4.1e-95	312.5	COG2086	Electron transfer flavoprotein, alpha and beta subunits	260
2918279511	313	99.69	1	312	1	317	6.4e-113	372.2	COG2025	Electron transfer flavoprotein, alpha subunit	313
2918279512	292	86.63	2	291	2	286	5.1e-116	381.9	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
2918279513	180	96.49	1	166	4	168	1.4e-20	68.6	COG3652	Predicted outer membrane protein	170
2918279514	220	95.33	50	190	3	145	3.3e-14	47.7	COG0526	Thiol-disulfide isomerase or thioredoxin	127
2918279515	470	98.91	12	470	3	456	0.0e+00	662.7	COG0165	Argininosuccinate lyase	459
2918279517	421	99.24	1	392	4	395	0.0e+00	442.1	COG0019	Diaminopimelate decarboxylase	394
2918279519	711	98.94	19	681	3	658	0.0e+00	1081.8	COG0556	Excinuclease UvrABC helicase subunit UvrB	663
2918279521	290	98.25	10	290	2	281	8.6e-83	273	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
2918279522	163	90.23	14	145	5	124	7.0e-20	65.8	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918279524	91	96	1	74	1	72	1.1e-33	109	COG0361	Translation initiation factor IF-1	75
2918279525	69	98.51	1	69	1	66	9.8e-32	103.5	COG1278	Cold shock protein, CspA family	67
2918279526	712	65.38	581	712	10	128	8.5e-12	38.4	COG4567	Two-component response regulator, ActR/RegA family, consists of REC and Fis-type HTH domains	182
2918279526	712	90.61	183	561	36	392	6.0e-60	198.6	COG0642	Signal transduction histidine kinase	336
2918279527	353	96.35	3	301	8	297	4.1e-40	132	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918279528	235	99.14	10	235	2	231	3.1e-73	240.5	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918279529	454	83.5	91	454	59	387	4.9e-53	175.3	COG0642	Signal transduction histidine kinase	336
2918279530	225	90.38	1	220	13	228	8.4e-20	65	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
2918279531	111	69.72	1	109	10	108	4.5e-20	66.4	COG0073	tRNA-binding EMAP/Myf domain	123
2918279532	148	75.32	7	140	39	157	1.2e-20	68.8	COG5490	Uncharacterized protein	158
2918279533	230	71.77	8	225	17	166	2.6e-11	38.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918279535	462	96.12	44	461	15	410	0.0e+00	462.5	COG2262	50S ribosomal subunit-associated GTPase HflX	411
2918279538	621	98.27	1	614	10	577	0.0e+00	791.1	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
2918279539	1035	69.02	584	1030	90	343	1.2e-10	35.9	COG0457	Tetratricopeptide (TPR) repeat	291
2918279539	1035	82.38	17	231	36	236	2.1e-38	124.4	COG2114	Adenylate cyclase, class 3	227
2918279540	102	65.69	12	100	15	81	2.6e-16	53.7	COG4321	Predicted DNA-binding protein, contains Ribbon-helix-helix (RHH) domain	102
2918279542	422	96.76	18	419	5	392	2.3e-89	294.2	COG1944	Ribosomal protein S12 methylthiotransferase accessory factor YcaO	398
2918279543	254	96.71	1	248	5	239	1.1e-77	255.1	COG3482	Uncharacterized protein	237
2918279544	236	98.62	8	223	2	216	8.4e-43	140.9	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2918279545	128	69.61	11	117	15	85	8.1e-11	36	COG4321	Predicted DNA-binding protein, contains Ribbon-helix-helix (RHH) domain	102
2918279546	680	20.6	125	259	91	159	9.8e-04	10.2	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
2918279546	680	21.79	21	126	102	174	9.8e-04	6.3	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
2918279546	680	80.71	250	664	72	389	1.1e-57	189.9	COG0642	Signal transduction histidine kinase	336
2918279547	125	92.48	1	124	5	127	5.3e-25	82.4	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918279548	147	86.47	11	142	15	129	3.7e-15	50.5	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918279549	453	98.87	16	452	3	438	0.0e+00	455.3	COG0621	tRNA A37 methylthiotransferase MiaB	437
2918279550	111	43.23	4	85	73	139	1.6e-11	38.7	COG1403	5-methylcytosine-specific restriction endonuclease McrA	146
2918279555	256	12.8	2	62	32	79	1.9e-39	16.8	COG3240	Phospholipase/lecithinase/hemolysin	370
2918279555	256	60.8	21	249	108	335	1.9e-39	119.4	COG3240	Phospholipase/lecithinase/hemolysin	370
2918279557	1867	77.78	99	511	91	447	3.4e-87	287.2	COG3281	Predicted trehalose synthase	438
2918279557	1867	92.26	526	1135	17	600	0.0e+00	537	COG0296	1,4-alpha-glucan branching enzyme	628
2918279557	1867	98.11	1307	1864	7	525	0.0e+00	542.5	COG1640	4-alpha-glucanotransferase	520
2918279558	927	99.66	7	926	3	888	0.0e+00	1016.3	COG3280	Maltooligosyltrehalose synthase	889
2918279559	148	77.59	2	118	26	115	8.9e-29	94.3	COG3450	Predicted enzyme of the cupin superfamily	116
2918279560	504	74.87	117	491	98	392	1.8e-37	124.3	COG0642	Signal transduction histidine kinase	336
2918279564	147	49.57	1	116	2	116	1.2e-13	45.5	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918279567	218	68.89	9	214	55	209	6.0e-45	147.7	COG2979	Uncharacterized membrane protein YebE, DUF533 family	225
2918279569	260	96.23	2	257	11	265	4.1e-68	224.2	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918279570	233	97.67	1	214	1	210	7.5e-58	190.5	COG0625	Glutathione S-transferase	211
2918279571	471	79.57	5	467	112	555	0.0e+00	481.1	COG3829	Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding Fis domains	560
2918279572	261	99.63	1	260	1	267	1.6e-73	242.2	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918279573	650	99.82	79	631	1	551	0.0e+00	527	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
2918279574	326	96.9	15	323	8	320	6.3e-86	283	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918279575	295	98.01	9	295	3	297	1.2e-84	278.8	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2918279576	400	97.27	13	378	8	363	6.4e-48	158.1	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918279577	240	99.58	9	240	2	237	5.5e-87	285.4	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2918279578	257	99.61	2	248	2	254	1.6e-87	287.5	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2918279580	58	9.46	1	47	419	462	5.4e-03	10.1	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
2918279581	233	97.5	1	232	1	234	1.9e-62	205.4	COG5446	Uncharacterized membrane protein, predicted cobalt tansporter CbtA	233
2918279582	346	97.24	10	345	1	317	1.5e-93	308.2	COG0523	GTPase, G3E family	323
2918279583	1128	30.77	685	1128	829	1265	0.0e+00	519.2	COG1429	Cobalamin biosynthesis protein CobN, Mg-chelatase	1388
2918279583	1128	51.27	6	692	15	742	0.0e+00	555.7	COG1429	Cobalamin biosynthesis protein CobN, Mg-chelatase	1388
2918279584	437	86.58	2	432	30	474	6.8e-63	207.3	COG0155	Sulfite reductase, beta subunit (hemoprotein)	510
2918279585	212	96.21	4	212	4	206	2.9e-76	250.3	COG2082	Precorrin isomerase	210
2918279586	246	98.72	8	246	2	233	9.7e-72	235.9	COG2243	Precorrin-2 methylase	234
2918279587	255	97.2	2	255	3	245	1.1e-93	307.8	COG1010	Precorrin-3B methylase	249
2918279588	251	96.89	1	246	4	252	7.9e-79	259.2	COG2099	Precorrin-6x reductase	257
2918279589	408	99.05	9	216	1	208	2.4e-63	207.8	COG2241	Precorrin-6B methylase 1	210
2918279589	408	99.47	224	407	1	186	1.2e-68	223.8	COG2242	Precorrin-6B methylase 2	187
2918279590	128	34.28	1	123	203	311	2.4e-21	70.9	COG2073	Cobalamin biosynthesis protein CbiG	298
2918279591	253	98.04	1	253	3	252	3.0e-106	348.9	COG2875	Precorrin-4 methylase	254
2918279592	376	97.28	1	367	5	361	4.6e-110	362.5	COG1903	Cobalamin biosynthesis protein CbiD	367
2918279593	263	98.36	14	257	3	242	1.4e-88	291.3	COG0007	Uroporphyrinogen-III methylase (siroheme synthase)	244
2918279594	440	96.91	3	440	2	440	0.0e+00	498.4	COG1797	Cobyrinic acid a,c-diamide synthase	451
2918279595	218	97.69	9	214	2	212	3.2e-34	113.3	COG0778	Nitroreductase	207
2918279597	561	97.46	23	406	4	386	2.5e-69	228.8	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2918279598	415	97.65	19	406	4	377	2.9e-11	35.5	COG0477	MFS family permease	338
2918279599	508	84.85	7	496	51	498	2.5e-55	180.5	COG0737	2',3'-cyclic-nucleotide 2'-phosphodiesterase/5'- or 3'-nucleotidase, 5'-nucleotidase family	517
2918279600	815	67.51	463	808	127	392	2.8e-48	160.3	COG0642	Signal transduction histidine kinase	336
2918279601	979	35.03	226	377	35	172	2.6e-54	8.2	COG0642	Signal transduction histidine kinase	336
2918279601	979	67.01	379	841	127	390	2.6e-54	180.1	COG0642	Signal transduction histidine kinase	336
2918279601	979	88.72	854	979	6	123	4.8e-20	64.5	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918279602	195	51.44	50	188	35	141	4.9e-09	28	COG0288	Carbonic anhydrase	207
2918279603	447	95.62	6	353	6	354	4.5e-73	236.7	COG1858	Cytochrome c peroxidase	364
2918279605	391	89.28	15	386	31	363	5.1e-54	177.8	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
2918279606	317	97.34	13	314	1	293	1.5e-49	163.9	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918279607	214	94.42	5	214	3	205	1.7e-28	94.7	COG0625	Glutathione S-transferase	211
2918279609	724	90.59	270	719	39	423	2.9e-51	169.8	COG0840	Methyl-accepting chemotaxis protein	408
2918279610	213	52.31	31	151	3	70	2.2e-12	42.4	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918279611	532	65.74	44	393	128	386	6.0e-53	175.2	COG0642	Signal transduction histidine kinase	336
2918279612	266	52.16	4	125	2	122	4.3e-29	12.9	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918279612	266	52.59	127	261	2	123	4.3e-29	85.1	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918279613	366	98.58	7	365	1	347	9.8e-90	295.6	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
2918279614	725	20.56	1	160	3	157	5.8e-120	61.3	COG0643	Chemotaxis protein histidine kinase CheA	716
2918279614	725	52.79	126	599	345	742	5.8e-120	337.1	COG0643	Chemotaxis protein histidine kinase CheA	716
2918279614	725	90.98	601	725	6	126	4.4e-32	104	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918279615	558	88	54	558	52	425	2.0e-74	244.9	COG0840	Methyl-accepting chemotaxis protein	408
2918279616	180	79.39	24	177	27	157	1.1e-10	35.8	COG0835	Chemotaxis signal transduction protein	165
2918279617	464	98.15	10	284	3	267	1.9e-67	221.8	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
2918279618	172	89.7	1	152	13	160	9.8e-16	52.2	COG0835	Chemotaxis signal transduction protein	165
2918279620	161	91.18	10	161	10	133	2.4e-26	86.8	COG4520	Surface antigen	136
2918279621	443	73.64	3	316	39	309	2.1e-11	38.7	COG0457	Tetratricopeptide (TPR) repeat	291
2918279622	248	99.25	2	247	2	267	1.0e-63	210	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918279628	139	88.89	1	135	4	131	4.5e-30	99.1	COG2703	Hemerythrin	144
2918279632	226	97.31	1	222	1	217	3.6e-86	283	COG2884	ABC-type ATPase involved in cell division	223
2918279633	297	91.92	6	297	21	293	4.6e-33	109	COG2177	Cell division protein FtsX	297
2918279634	213	81.82	9	208	32	220	1.4e-19	65	COG1434	Uncharacterized SAM-binding protein YcdF, DUF218 family	223
2918279635	258	81.23	9	254	26	237	1.2e-33	111.1	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
2918279636	785	87.16	4	613	92	756	0.0e+00	449.9	COG0209	Ribonucleotide reductase alpha subunit	696
2918279637	390	98.04	1	390	3	403	3.7e-95	313.8	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
2918279638	118	37.21	21	117	53	100	5.4e-06	20.8	COG0662	Mannose-6-phosphate isomerase, cupin superfamily	127
2918279639	332	91.96	6	332	13	355	3.4e-64	211.5	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
2918279641	436	81.18	3	430	79	423	1.4e-55	178.5	COG0840	Methyl-accepting chemotaxis protein	408
2918279642	174	40.08	4	156	133	229	1.1e-09	33.2	COG2202	PAS domain	232
2918279644	146	96.59	1	88	1	85	1.7e-30	99.3	COG0851	Septum formation topological specificity factor MinE	88
2918279645	271	98.53	1	271	2	269	2.6e-128	421.5	COG2894	Septum formation inhibitor-activating ATPase MinD	272
2918279646	251	97.82	14	251	3	226	2.1e-56	185.9	COG0850	Septum formation inhibitor MinC	219
2918279648	246	61.47	13	246	115	323	7.3e-94	309.3	COG1702	Phosphate starvation-inducible protein PhoH, predicted ATPase	348
2918279649	711	81.65	54	555	78	424	2.4e-61	202.3	COG0840	Methyl-accepting chemotaxis protein	408
2918279649	711	90.97	576	711	4	134	8.8e-31	100.5	COG2703	Hemerythrin	144
2918279650	200	93.33	1	199	8	203	1.7e-60	198.7	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
2918279651	121	81.03	1	115	6	99	1.2e-19	64.9	COG5336	FoF1-type ATP synthase assembly protein I	116
2918279652	247	97.62	1	247	7	252	3.1e-64	211.4	COG0356	FoF1-type ATP synthase, membrane subunit a	246
2918279653	74	88.75	1	74	8	78	1.3e-20	68	COG0636	FoF1-type ATP synthase, membrane subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K	79
2918279654	215	93.79	56	214	7	157	7.6e-28	91.5	COG0711	FoF1-type ATP synthase, membrane subunit b or b'	161
2918279655	159	95.03	1	157	7	159	1.9e-29	97	COG0711	FoF1-type ATP synthase, membrane subunit b or b'	161
2918279656	260	96.65	1	256	9	268	3.2e-78	257.5	COG3384	Aromatic ring-opening dioxygenase, catalytic subunit, LigB family	268
2918279657	666	81.98	256	646	66	388	4.8e-62	205.5	COG0642	Signal transduction histidine kinase	336
2918279658	232	90.18	6	221	9	210	1.1e-52	173.3	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
2918279659	203	60.77	40	188	28	154	1.9e-12	41.3	COG5388	Uncharacterized protein	209
2918279660	324	17.27	234	322	153	238	2.3e-67	63.4	COG2319	WD40 repeat	466
2918279660	324	44.78	24	239	157	379	2.3e-67	158.6	COG2319	WD40 repeat	466
2918279662	337	94.04	117	335	2	206	6.0e-54	177.2	COG2864	Cytochrome b subunit of formate dehydrogenase	218
2918279664	198	75.12	1	194	11	164	2.2e-44	145.6	COG0437	Fe-S-cluster-containing dehydrogenase component	203
2918279665	962	99.63	26	962	2	808	0.0e+00	618.4	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
2918279668	212	89.71	14	211	10	192	2.1e-34	112.9	COG3381	Cytoplasmic chaperone TorD involved in molybdoenzyme TorA maturation	204
2918279671	207	97.94	1	201	3	192	6.8e-52	170.4	COG0746	Molybdopterin-guanine dinucleotide biosynthesis protein A	192
2918279672	311	92.51	31	288	20	266	1.7e-59	195.7	COG1526	Formate dehydrogenase assembly factor FdhD	266
2918279673	231	96.92	2	228	5	224	1.5e-69	228.3	COG4662	ABC-type tungstate transport system, periplasmic component	227
2918279674	283	92.14	5	282	17	274	5.7e-103	338.1	COG2998	ABC-type tungstate transport system, permease component	280
2918279675	158	83.54	5	156	25	156	9.7e-21	67.2	COG5490	Uncharacterized protein	158
2918279676	108	88.79	3	108	12	106	4.9e-45	146.5	COG2127	ATP-dependent Clp protease adapter protein ClpS	107
2918279677	771	41.61	415	751	468	802	0.0e+00	464.5	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
2918279677	771	49.81	1	423	2	402	0.0e+00	522.2	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
2918279678	370	94.01	1	370	9	385	1.4e-98	325.1	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2918279679	162	35.65	6	158	143	260	9.5e-09	29.4	COG0790	TPR repeat	292
2918279680	158	94.77	1	152	6	150	5.1e-43	141.4	COG0590	tRNA(Arg) A34 adenosine deaminase TadA	152
2918279681	387	98.71	1	385	5	386	0.0e+00	523.5	COG3146	Predicted N-acyltransferase	387
2918279682	155	96.32	8	155	4	134	1.9e-21	71	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
2918279683	621	99.74	1	621	1	387	1.4e-21	62.7	COG1344	Flagellin and related hook-associated protein FlgL	360
2918279684	510	90.22	10	507	33	484	4.1e-81	267.6	COG2939	Carboxypeptidase C (cathepsin A)	498
2918279685	141	70.14	1	140	15	162	1.2e-24	81.8	COG2391	Uncharacterized membrane protein YedE/YeeE, contains two sulfur transport domains	198
2918279686	157	67.3	4	150	21	162	3.0e-20	67.5	COG2391	Uncharacterized membrane protein YedE/YeeE, contains two sulfur transport domains	198
2918279687	159	91.67	9	147	3	134	6.0e-28	92.1	COG2703	Hemerythrin	144
2918279689	479	93.22	3	416	2	400	1.5e-98	324.9	COG1696	D-alanyl-lipoteichoic acid acyltransferase DltB, MBOAT superfamily	425
2918279690	1238	98.95	24	978	3	757	0.0e+00	531.4	COG0209	Ribonucleotide reductase alpha subunit	696
2918279691	165	54.55	55	135	7	54	2.8e-05	18.2	COG1873	Sporulation protein YlmC, PRC-barrel domain family	87
2918279694	316	93.18	12	315	17	303	1.3e-60	199.4	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
2918279695	206	53.63	6	202	82	214	5.0e-51	168.5	COG0797	Rare lipoprotein A, peptidoglycan hydrolase digesting "naked" glycans, contains C-terminal SPOR domain	233
2918279696	272	83.77	4	244	7	228	8.6e-60	196.4	COG0300	Short-chain dehydrogenase	265
2918279697	150	88.68	4	150	17	157	1.3e-35	116.6	COG2030	Acyl dehydratase	159
2918279698	316	100	1	311	1	307	9.1e-106	348	COG0196	FAD synthase	304
2918279700	231	96.55	12	218	5	200	2.1e-44	146.3	COG0461	Orotate phosphoribosyltransferase	201
2918279702	951	99.58	3	948	2	944	0.0e+00	1100.1	COG0060	Isoleucyl-tRNA synthetase	933
2918279703	167	92.81	5	167	8	162	6.6e-44	143.9	COG0597	Lipoprotein signal peptidase	167
2918279705	454	94.74	26	453	18	431	7.7e-109	358.5	COG0612	Predicted Zn-dependent peptidase	438
2918279706	446	97.03	11	438	8	431	1.0e-81	269.2	COG0612	Predicted Zn-dependent peptidase	438
2918279708	547	99.34	39	537	3	452	0.0e+00	649.7	COG0166	Glucose-6-phosphate isomerase	446
2918279711	149	95.86	4	147	2	140	7.8e-52	169.7	COG3304	Uncharacterized membrane protein YccF, DUF307 family	145
2918279714	218	92.64	73	197	12	162	2.0e-24	81.2	COG0517	CBS domain	117
2918279716	404	99.25	10	402	2	396	0.0e+00	451.4	COG0282	Acetate kinase	396
2918279717	484	15.9	192	256	22	73	8.8e-69	18.5	COG0280	Phosphotransacetylase	327
2918279717	484	67.28	248	476	106	325	8.8e-69	206	COG0280	Phosphotransacetylase	327
2918279717	484	92.45	13	160	10	156	1.2e-34	112.8	COG2030	Acyl dehydratase	159
2918279718	739	66.5	292	726	127	388	1.6e-51	170.7	COG0642	Signal transduction histidine kinase	336
2918279719	470	57.61	36	324	165	391	4.2e-27	90.1	COG0642	Signal transduction histidine kinase	336
2918279719	470	93.23	340	469	7	130	1.9e-15	50.5	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918279720	417	66.5	69	399	128	389	1.5e-78	259.5	COG0642	Signal transduction histidine kinase	336
2918279721	156	78.66	8	154	24	152	1.3e-51	168.9	COG5321	Uncharacterized protein	164
2918279722	256	92.48	3	223	4	126	3.1e-35	115.5	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918279723	695	58.87	496	641	38	110	6.6e-22	32.2	COG1145	Ferredoxin	99
2918279723	695	63.71	237	350	26	104	6.6e-22	43.4	COG1145	Ferredoxin	99
2918279724	346	99.69	16	346	2	325	4.1e-120	395.1	COG2896	Molybdenum cofactor biosynthesis enzyme MoaA	322
2918279725	284	82.46	27	283	33	267	6.0e-53	174.3	COG0061	NAD kinase	281
2918279726	292	92.28	7	290	14	264	3.4e-58	191.4	COG3741	N-formylglutamate amidohydrolase	272
2918279727	316	62.73	17	259	39	245	2.3e-16	53.9	COG3608	Predicted deacylase	331
2918279728	356	96.31	7	352	10	348	2.1e-65	215.3	COG3180	Uncharacterized membrane protein AbrB, regulator of aidB expression	352
2918279729	172	94.55	10	171	9	164	2.2e-57	187.6	COG3045	Periplasmic catabolite regulation protein CreA (function unknown)	165
2918279730	370	94.17	20	369	9	347	1.0e-61	203.4	COG0628	Predicted PurR-regulated permease PerM	355
2918279731	336	96.35	3	299	6	295	6.3e-91	299.3	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
2918279732	142	97.87	1	142	3	140	2.3e-37	123.1	COG1585	Membrane protein implicated in regulation of membrane protease activity	140
2918279733	323	95.68	30	320	8	295	1.7e-41	136.9	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918279734	137	22.38	12	134	196	276	1.4e-07	25.6	COG0349	Ribonuclease D	361
2918279737	123	76.07	23	123	16	104	1.6e-16	54.7	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
2918279739	156	26.4	8	82	29	75	2.3e-12	5.6	COG1633	Rubrerythrin	176
2918279739	156	33.15	78	155	20	78	2.3e-12	39	COG1633	Rubrerythrin	176
2918279740	173	80.1	7	168	20	172	2.6e-52	171.7	COG4420	Uncharacterized membrane protein	191
2918279741	846	93.8	2	845	54	870	0.0e+00	751.1	COG1643	HrpA-like RNA helicase	845
2918279742	414	86.07	176	411	22	231	1.4e-43	143	COG2114	Adenylate cyclase, class 3	227
2918279743	361	99.19	53	302	3	248	2.4e-72	237.6	COG1180	Pyruvate-formate lyase-activating enzyme	260
2918279744	453	92.2	263	453	5	193	5.8e-31	101.7	COG2078	Uncharacterized conserved protein, AMMECR1 domain	203
2918279744	453	98.91	1	260	1	272	1.3e-47	156.2	COG1355	Predicted class III extradiol dioxygenase, MEMO1 family	279
2918279746	518	97.18	5	516	6	487	0.0e+00	646.8	COG2719	Stage V sporulation protein SpoVR/YcgB, involved in spore cortex formation (function unknown)	495
2918279747	431	98.82	1	431	3	421	0.0e+00	494.4	COG2718	Uncharacterized conserved protein YeaH/YhbH, required for sporulation, DUF444 family	423
2918279748	648	99.54	5	648	2	648	0.0e+00	949.8	COG2766	Predicted Ser/Thr protein kinase	649
2918279749	130	89.47	6	130	6	124	4.2e-27	89.2	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918279750	282	64.53	114	275	28	138	4.8e-07	23.7	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2918279751	283	56.04	1	281	10	278	5.1e-86	284.2	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
2918279753	187	99.35	22	168	1	154	9.2e-36	117.6	COG1403	5-methylcytosine-specific restriction endonuclease McrA	146
2918279754	43	32.43	3	38	10	33	6.2e-08	27.4	COG3313	Predicted Fe-S protein YdhL, DUF1289 family	74
2918279755	206	92.75	4	206	16	207	1.0e-63	209.1	COG2941	Demethoxyubiquinone hydroxylase, CLK1/Coq7/Cat5 family	204
2918279756	174	89.02	3	167	16	169	2.3e-27	90.6	COG1495	Disulfide bond formation protein DsbB	170
2918279758	129	83.09	2	129	20	132	2.0e-35	116.4	COG3474	Cytochrome c2	135
2918279759	186	45.61	37	179	61	112	1.5e-08	28.5	COG0607	Rhodanese-related sulfurtransferase	110
2918279760	335	89.55	6	331	9	308	7.2e-27	89	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918279761	253	94.96	1	251	11	255	1.2e-54	180.1	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2918279762	256	95.22	19	253	5	243	7.5e-73	239.5	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2918279764	217	99.05	1	212	2	210	5.2e-60	197.3	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918279765	581	82.02	3	581	120	753	0.0e+00	451.5	COG4993	Glucose dehydrogenase	773
2918279766	310	77.69	19	303	35	236	4.7e-24	79.9	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2918279767	269	92.57	4	148	12	148	5.9e-20	66.1	COG5501	Predicted secreted protein	148
2918279768	285	93.29	3	279	8	271	5.1e-21	67.2	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918279769	143	54.27	2	143	54	142	2.0e-18	61.4	COG2010	Cytochrome c, mono- and diheme variants	150
2918279770	391	25.68	249	365	256	349	1.5e-10	9.5	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918279770	391	41.8	52	241	29	181	1.5e-10	23.9	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918279771	323	24.32	218	323	83	180	1.4e-51	47.3	COG3391	DNA-binding beta-propeller fold protein YncE	381
2918279771	323	64.27	17	273	50	308	1.4e-51	136	COG3391	DNA-binding beta-propeller fold protein YncE	381
2918279772	246	74.84	2	244	4	232	4.5e-72	237.6	COG1131	ABC-type multidrug transport system, ATPase component	293
2918279773	270	75.09	21	260	58	277	1.0e-17	58.7	COG0842	ABC-type multidrug transport system, permease component	286
2918279774	884	72.84	366	749	101	387	4.3e-56	185.9	COG0642	Signal transduction histidine kinase	336
2918279775	399	98.68	20	396	6	380	1.4e-89	295.1	COG3287	Uncharacterized conserved protein, contains FIST_N domain	379
2918279777	130	95.69	1	114	4	114	6.1e-52	169.1	COG3564	Uncharacterized conserved protein, DUF779 family	116
2918279778	506	99.37	19	501	2	477	0.0e+00	595.6	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918279779	136	82.44	1	125	13	120	1.1e-35	117.1	COG2005	DNA-binding transcriptional regulator ModE (molybdenum-dependent)	130
2918279780	132	84.56	3	132	17	131	3.6e-42	138.3	COG3474	Cytochrome c2	135
2918279781	158	94.01	1	157	1	157	4.4e-37	121.9	COG1142	Fe-S-cluster-containing hydrogenase component 2	165
2918279782	615	98.69	1	615	3	604	0.0e+00	621.4	COG2414	Aldehyde:ferredoxin oxidoreductase	614
2918279783	434	91.63	3	430	2	395	5.8e-66	218.2	COG0446	NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase	415
2918279784	83	45.24	2	83	47	84	2.5e-06	22.4	COG1977	Molybdopterin converting factor, small subunit	84
2918279787	192	98.14	1	164	1	158	5.3e-45	147.5	COG1238	Uncharacterized membrane protein YqaA, SNARE-associated domain	161
2918279788	347	97.01	2	249	2	261	1.7e-57	189.3	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918279789	289	95.06	20	288	9	258	4.8e-55	181.2	COG0566	tRNA G18 (ribose-2'-O)-methylase SpoU	260
2918279791	125	29.7	9	122	198	287	2.6e-20	67.4	COG1234	Ribonuclease BN, tRNA processing enzyme	292
2918279792	198	41.25	15	182	15	139	2.2e-12	41.3	COG1234	Ribonuclease BN, tRNA processing enzyme	292
2918279793	213	94.25	42	213	4	167	3.7e-69	226.8	COG0225	Peptide methionine sulfoxide reductase MsrA	174
2918279794	173	62.2	1	164	29	158	2.3e-05	18.5	COG5388	Uncharacterized protein	209
2918279795	643	56.33	58	640	405	929	0.0e+00	754.8	COG1674	DNA segregation ATPase FtsK/SpoIIIE and related proteins	858
2918279796	164	91.86	1	163	5	162	2.7e-46	152.2	COG2318	Uncharacterized damage-inducible protein DinB (forms a four-helix bundle)	172
2918279797	204	94.25	3	171	4	167	4.6e-43	141.7	COG3576	Predicted flavin-nucleotide-binding protein, pyridoxine 5'-phosphate oxidase superfamily	173
2918279798	249	95.58	19	246	8	223	5.2e-51	168	COG1285	Uncharacterized membrane protein YhiD, involved in acid resistance	221
2918279799	118	27.38	30	117	91	136	3.1e-04	14.6	COG4960	Flp pilus assembly protein, protease CpaA	168
2918279801	1088	93.9	574	968	1	385	0.0e+00	266.7	COG0458	Carbamoylphosphate synthase large subunit	400
2918279801	1088	98.05	13	433	1	402	0.0e+00	701.6	COG0458	Carbamoylphosphate synthase large subunit	400
2918279802	157	98.68	6	157	1	150	1.5e-61	201.5	COG0782	Transcription elongation factor, GreA/GreB family	151
2918279805	104	19.92	14	94	47	96	1.2e-05	19.2	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2918279806	300	96.62	36	300	8	236	8.0e-41	134.6	COG0412	Dienelactone hydrolase	236
2918279807	162	81.65	1	136	24	152	2.1e-30	100.4	COG1522	DNA-binding transcriptional regulator, Lrp family	154
2918279808	309	95.14	1	303	14	326	1.9e-75	248.5	COG3660	Mitochondrial fission protein ELM1	329
2918279811	166	40.81	1	166	234	395	2.4e-52	172.7	COG0754	Glutathionylspermidine synthase	387
2918279812	243	43.07	4	187	2	172	4.5e-44	145.3	COG0754	Glutathionylspermidine synthase	387
2918279813	198	61.27	2	197	24	148	2.6e-18	60.6	COG5463	Uncharacterized conserved protein YgiB, involved in bioifilm formation, UPF0441/DUF1190 family	198
2918279814	137	95.49	4	137	6	132	8.3e-35	114.5	COG3766	Uncharacterized membrane protein YjfL, UPF0719 family	133
2918279816	327	99.35	4	320	2	306	5.0e-129	424.3	COG0492	Thioredoxin reductase	305
2918279817	152	93.06	14	152	7	140	2.1e-38	126.5	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
2918279818	319	93.08	19	296	13	281	5.4e-72	236.8	COG2041	Periplasmic DMSO/TMAO reductase YedYZ, molybdopterin-dependent catalytic subunit	271
2918279819	155	98.73	1	155	3	157	1.9e-57	188.3	COG0783	DNA-binding ferritin-like protein (oxidative damage protectant)	156
2918279820	405	64.46	14	226	87	242	2.1e-22	73.5	COG2202	PAS domain	232
2918279820	405	97.81	213	394	5	183	4.2e-58	190.5	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2918279821	570	91.29	14	564	36	423	4.5e-59	193.3	COG0840	Methyl-accepting chemotaxis protein	408
2918279822	154	18.74	15	154	95	180	2.6e-14	47.1	COG4564	Signal transduction histidine kinase	459
2918279823	309	96.44	1	307	1	298	6.2e-70	230.4	COG1893	Ketopantoate reductase	307
2918279824	679	97.94	1	675	8	721	0.0e+00	539.5	COG0480	Translation elongation factor EF-G, a GTPase	697
2918279825	276	84.81	1	243	41	269	2.1e-104	343.4	COG2326	Polyphosphate kinase 2, PPK2 family	270
2918279826	256	64.21	46	198	66	187	9.5e-29	93.6	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
2918279827	401	98.99	6	400	2	393	0.0e+00	439.9	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
2918279828	142	95.24	1	142	6	145	3.0e-25	83.8	COG3909	Cytochrome c556	147
2918279829	198	78.65	1	169	35	185	1.8e-36	119.7	COG3658	Cytochrome b	192
2918279832	170	94.09	1	169	6	180	4.6e-48	157.8	COG4186	Calcineurin-like phosphoesterase superfamily protein	186
2918279833	563	81.41	113	558	78	423	3.2e-66	219.1	COG0840	Methyl-accepting chemotaxis protein	408
2918279838	267	97.63	15	265	1	288	2.8e-26	83.4	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918279839	412	90.71	31	405	37	407	1.0e-46	154.2	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918279840	291	89.26	10	277	3	243	2.3e-53	175.8	COG0647	Ribonucleotide monophosphatase NagD, HAD superfamily	269
2918279841	112	66.67	6	99	15	82	1.6e-16	54.4	COG4321	Predicted DNA-binding protein, contains Ribbon-helix-helix (RHH) domain	102
2918279843	337	43.13	125	331	25	137	5.4e-13	43.1	COG3103	Uncharacterized conserved protein YgiM, contains N-terminal SH3 domain, DUF1202 family	205
2918279844	600	84.85	2	600	29	633	0.0e+00	541.2	COG0744	Membrane carboxypeptidase (penicillin-binding protein)	661
2918279845	368	80.17	40	314	12	201	1.6e-19	64.2	COG0412	Dienelactone hydrolase	236
2918279846	162	92.05	1	162	12	173	1.1e-77	254.2	COG0290	Translation initiation factor IF-3	176
2918279847	650	98.65	37	644	2	587	0.0e+00	860.9	COG0441	Threonyl-tRNA synthetase	589
2918279848	409	91.44	169	407	7	241	4.3e-43	141.1	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
2918279849	361	98.39	36	361	4	308	4.0e-105	345.8	COG0167	Dihydroorotate dehydrogenase	310
2918279850	125	98.26	1	115	2	114	3.5e-43	140.9	COG3502	Uncharacterized conserved protein, DUF952 family	115
2918279852	165	18.62	110	165	195	240	1.2e-11	10.7	COG3773	Cell wall hydrolase CwlJ, involved in spore germination	249
2918279852	165	19.43	1	62	105	152	1.2e-11	26	COG3773	Cell wall hydrolase CwlJ, involved in spore germination	249
2918279863	768	64.71	260	764	214	642	1.2e-106	351.6	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2918279863	768	82.14	132	213	6	74	4.0e-03	11.9	COG2770	HAMP domain	83
2918279869	210	98.7	1	210	1	228	3.6e-52	172.2	COG2932	Phage repressor protein C, contains Cro/C1-type HTH and peptisase s24 domains	214
2918279872	293	97.54	19	293	4	281	2.7e-57	189.3	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
2918279874	258	96.6	26	258	4	230	8.6e-91	297.8	COG0479	Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit	234
2918279875	593	99.47	4	577	3	565	0.0e+00	767.6	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
2918279876	133	97.44	14	130	3	116	9.3e-28	91.1	COG2142	Succinate dehydrogenase, hydrophobic anchor subunit	117
2918279877	129	96.99	5	129	3	131	7.3e-32	105.1	COG2009	Succinate dehydrogenase/fumarate reductase, cytochrome b subunit	132
2918279878	423	25.8	132	406	267	363	2.9e-04	13.9	COG4399	Uncharacterized membrane protein YheB, UPF0754 family	376
2918279880	338	99.4	2	333	2	335	0.0e+00	444.6	COG0136	Aspartate-semialdehyde dehydrogenase	334
2918279881	290	99.3	8	289	2	285	7.3e-98	321.9	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
2918279882	134	78.47	4	121	26	138	1.1e-11	39.1	COG3793	Tellurite resistance protein	144
2918279883	315	98.08	1	313	2	308	1.9e-51	169.5	COG0679	Predicted permease	311
2918279885	309	98.7	1	307	1	303	0.0e+00	444.9	COG1897	Homoserine trans-succinylase	307
2918279886	919	96.76	203	917	12	667	2.7e-123	406.9	COG1199	Rad3-related DNA helicase	654
2918279887	228	23.56	4	219	87	254	5.1e-69	228.1	COG0744	Membrane carboxypeptidase (penicillin-binding protein)	661
2918279888	107	97.17	1	105	2	104	6.1e-38	124.2	COG2076	Multidrug transporter EmrE and related cation transporters	106
2918279889	378	51.99	55	377	147	329	1.4e-66	220	COG2206	HD-GYP domain, c-di-GMP phosphodiesterase class II (or its inactivated variant)	344
2918279890	522	99.62	11	520	2	520	0.0e+00	541.7	COG1384	Lysyl-tRNA synthetase, class I	521
2918279891	201	91.05	14	191	5	177	1.9e-51	169.1	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
2918279893	420	79.67	73	401	21	310	9.3e-24	78.8	COG5330	Uncharacterized conserved protein, DUF2336 family	364
2918279895	322	99.05	4	318	1	312	1.3e-120	396.9	COG0039	Malate/lactate dehydrogenase	313
2918279896	398	99.74	1	397	1	382	0.0e+00	531.9	COG0045	Succinyl-CoA synthetase, beta subunit	387
2918279897	291	98.98	1	291	1	291	0.0e+00	439.3	COG0074	Succinyl-CoA synthetase, alpha subunit	293
2918279898	974	99.46	2	973	5	922	0.0e+00	1319.7	COG0567	2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes	906
2918279899	417	99.77	1	416	1	433	0.0e+00	522.3	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
2918279900	369	95.63	7	369	6	355	2.7e-90	297.6	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918279901	824	71.83	240	685	109	391	9.9e-61	201.2	COG0642	Signal transduction histidine kinase	336
2918279901	824	92.48	693	820	7	129	1.5e-17	57	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918279902	524	97.49	1	509	5	509	0.0e+00	478.9	COG0728	Peptidoglycan biosynthesis protein MviN/MurJ, putative lipid II flippase	518
2918279903	332	97.79	1	311	7	316	2.5e-105	346.8	COG0180	Tryptophanyl-tRNA synthetase	314
2918279904	205	95.17	3	203	3	199	1.8e-46	153.3	COG2039	Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase)	207
2918279905	211	98.14	1	207	2	212	1.6e-41	137.1	COG0625	Glutathione S-transferase	211
2918279906	456	97.76	4	454	6	442	0.0e+00	526.1	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
2918279907	404	100	1	395	1	390	0.0e+00	467.7	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
2918279910	258	68.8	1	128	23	108	3.8e-07	24.6	COG2198	HPt (histidine-containing phosphotransfer) domain	122
2918279910	258	73.68	134	254	7	104	2.6e-10	34.5	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918279911	248	98.51	4	246	4	267	1.4e-62	206.1	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918279912	398	70.17	50	282	48	254	1.1e-32	107.8	COG3016	Uncharacterized iron-regulated protein	295
2918279914	118	96.43	2	118	5	112	1.0e-47	155.5	COG2824	Uncharacterized Zn-ribbon-containing protein	112
2918279915	190	94.52	36	171	5	142	2.5e-24	80.3	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
2918279916	475	91.98	14	475	16	428	2.7e-86	279.1	COG1322	DNA anti-recombination protein (rearrangement mutator) RmuC	448
2918279917	69	98.51	1	69	1	66	6.3e-31	100.9	COG1278	Cold shock protein, CspA family	67
2918279919	170	99.41	1	167	1	168	8.6e-65	212	COG0242	Peptide deformylase	168
2918279920	318	98.05	3	306	2	303	4.8e-119	391.7	COG0223	Methionyl-tRNA formyltransferase	307
2918279921	245	91.76	1	245	1	245	8.2e-78	256	COG0101	tRNA U38,U39,U40 pseudouridine synthase TruA	266
2918279922	441	98.01	137	439	3	297	5.3e-77	253.4	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2918279923	467	99.07	2	467	3	427	0.0e+00	649.2	COG0065	Homoaconitase/3-isopropylmalate dehydratase large subunit	423
2918279926	579	99.54	104	557	2	433	0.0e+00	731.2	COG0422	Thiamine biosynthesis protein ThiC	432
2918279928	299	95.02	4	299	10	295	4.6e-41	135.6	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918279929	136	95.9	3	124	5	121	8.5e-53	172	COG0335	Ribosomal protein L19	115
2918279930	267	94.67	11	260	3	233	1.2e-91	300.6	COG0336	tRNA G37 N-methylase TrmD	240
2918279931	182	93.68	1	168	8	170	3.9e-41	135.1	COG0806	Ribosomal 30S subunit maturation factor RimM, required for 16S rRNA processing	174
2918279932	120	93.33	2	98	2	85	7.2e-35	111.7	COG0228	Ribosomal protein S16	87
2918279933	455	97.57	1	452	1	441	0.0e+00	599.4	COG0541	Signal recognition particle GTPase	451
2918279935	455	42.63	139	277	95	201	1.7e-85	78.4	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2918279935	455	61.35	275	450	63	216	1.7e-85	131.8	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2918279935	455	63.75	8	189	82	241	1.7e-85	98.6	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2918279938	114	82.95	2	113	17	123	2.3e-42	138.4	COG2852	Very-short-patch-repair endonuclease	129
2918279940	436	18.41	317	406	242	308	4.0e-29	7.4	COG5330	Uncharacterized conserved protein, DUF2336 family	364
2918279940	436	55.77	66	290	26	228	4.0e-29	92.6	COG5330	Uncharacterized conserved protein, DUF2336 family	364
2918279941	573	69.83	20	235	71	239	3.5e-10	33.3	COG2202	PAS domain	232
2918279941	573	93.44	374	552	12	182	7.8e-47	153.4	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2918279942	225	86.58	5	216	4	203	3.5e-37	123.1	COG1011	FMN phosphatase YigB, HAD superfamily	229
2918279946	280	98.53	3	280	3	270	9.8e-96	315.1	COG2171	Tetrahydrodipicolinate N-succinyltransferase	271
2918279947	388	97.37	1	385	8	414	6.6e-99	326.4	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
2918279949	1061	66.75	524	924	127	389	1.3e-59	197.5	COG0642	Signal transduction histidine kinase	336
2918279949	1061	90.98	936	1060	7	127	7.5e-16	50.8	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918279950	342	96.86	11	342	2	340	2.0e-112	370.1	COG2038	NaMN:DMB phosphoribosyltransferase	347
2918279951	258	96.39	13	258	5	244	1.9e-57	189.5	COG0368	Cobalamin synthase	246
2918279952	209	91.39	3	204	4	194	1.5e-34	114	COG0406	Broad specificity phosphatase PhoE	208
2918279953	169	91.03	5	148	3	134	3.7e-42	138.1	COG3871	General stress protein 26 (function unknown)	145
2918279954	406	99.03	4	406	3	412	1.1e-127	420.9	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
2918279955	84	95.06	1	80	3	79	4.5e-18	59.9	COG0236	Acyl carrier protein	80
2918279956	377	96.45	1	357	2	327	5.5e-86	276	COG1044	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase	338
2918279957	274	79.62	38	266	46	256	2.1e-07	23.9	COG1682	ABC-type polysaccharide/polyol phosphate export permease	263
2918279958	272	76.14	16	272	4	236	3.3e-74	244.7	COG1131	ABC-type multidrug transport system, ATPase component	293
2918279959	436	84.26	13	435	56	387	1.3e-24	82	COG0642	Signal transduction histidine kinase	336
2918279960	194	95.6	14	193	9	182	8.9e-80	261.3	COG4567	Two-component response regulator, ActR/RegA family, consists of REC and Fis-type HTH domains	182
2918279962	567	63.68	402	565	26	167	2.2e-22	74.8	COG1226	Voltage-gated potassium channel Kch	212
2918279962	567	96.57	1	411	3	396	0.0e+00	607.4	COG4651	Predicted Kef-type K+ transport protein, K+/H+ antiporter domain	408
2918279963	82	40	10	81	7	58	1.1e-08	30.8	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918279965	227	97.71	8	214	3	215	4.2e-17	56.9	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2918279966	752	78.32	504	752	28	251	2.1e-39	128.9	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
2918279966	752	96.56	19	499	16	464	1.1e-105	348.3	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
2918279967	481	96.27	1	469	6	469	2.8e-65	215.3	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
2918279968	451	95.18	4	434	10	424	4.7e-86	283.5	COG0677	UDP-N-acetyl-D-mannosaminuronate dehydrogenase	436
2918279969	329	98.13	1	321	3	317	1.5e-72	239.4	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2918279970	324	98.44	1	311	3	318	7.9e-75	246.9	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2918279971	418	73.11	20	417	106	404	1.1e-24	82.6	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918279972	397	67.97	8	376	106	383	6.6e-30	99.7	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918279973	382	39.36	11	362	184	344	3.2e-20	68	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918279977	324	73.8	6	298	2	232	1.2e-32	107.8	COG1216	Glycosyltransferase, GT2 family	305
2918279978	311	94.57	3	277	3	298	9.8e-35	106.6	COG1216	Glycosyltransferase, GT2 family	305
2918279980	44	100	1	44	1	44	3.6e-25	82.5	COG0230	Ribosomal protein L34	44
2918279981	144	88.14	8	129	6	109	6.0e-26	85.2	COG0594	RNase P protein component	117
2918279982	93	76.09	1	87	8	77	5.9e-33	106.5	COG0759	Membrane-anchored protein YidD, putatitve component of membrane protein insertase Oxa1/YidC/SpoIIIJ	92
2918279983	575	92.7	258	573	2	293	1.8e-100	330.7	COG0706	Membrane protein insertase Oxa1/YidC/SpoIIIJ, required for the localization of integral membrane proteins	314
2918279984	221	96.5	23	220	3	195	6.0e-70	229.3	COG0218	GTP-binding protein EngB required for normal cell division	200
2918279985	422	91	6	417	17	380	3.1e-55	181.9	COG0475	Kef-type K+ transport system, membrane component KefB	397
2918279987	308	98.87	36	307	2	263	1.9e-106	349.6	COG0548	Acetylglutamate kinase	265
2918279989	327	90.55	13	327	32	328	3.1e-53	175.2	COG0598	Mg2+ and Co2+ transporter CorA	322
2918279992	60	27.59	1	50	96	135	1.1e-04	16.7	COG1730	Prefoldin subunit 5	145
2918279993	178	24.72	97	143	41	62	3.7e+00	3.2	COG1987	Flagellar biosynthesis protein FliQ	89
2918279993	178	29.21	48	82	11	36	3.7e+00	9.2	COG1987	Flagellar biosynthesis protein FliQ	89
2918279994	318	98.74	1	316	2	314	0.0e+00	449.9	COG0825	Acetyl-CoA carboxylase alpha subunit	317
2918279995	309	96.01	13	307	9	297	3.6e-26	86.6	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918279996	204	35.64	106	193	10	81	4.3e-26	18.1	COG1776	Chemotaxis protein CheY-P-specific phosphatase CheC	203
2918279996	204	62.38	6	148	9	134	4.3e-26	73.5	COG1776	Chemotaxis protein CheY-P-specific phosphatase CheC	203
2918279997	119	90.98	1	119	5	125	5.4e-19	63.1	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918279998	150	95.77	8	149	2	137	2.1e-24	80.7	COG1569	Predicted nucleic acid-binding protein, contains PIN domain	142
2918280000	194	84.62	3	192	29	204	3.2e-38	125.8	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
2918280001	385	66.58	67	377	101	345	1.2e-34	114.3	COG2208	Serine phosphatase RsbU, regulator of sigma subunit	367
2918280002	257	22.6	110	160	25	57	6.7e-06	6.5	COG2172	Anti-sigma regulatory factor (Ser/Thr protein kinase)	146
2918280002	257	38.36	196	255	75	130	6.7e-06	11.8	COG2172	Anti-sigma regulatory factor (Ser/Thr protein kinase)	146
2918280003	151	85.47	49	151	5	104	1.3e-13	45.3	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
2918280004	771	67.01	318	757	127	390	1.9e-45	151	COG0642	Signal transduction histidine kinase	336
2918280005	996	38.36	39	192	2	90	3.4e-27	16.2	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918280005	996	58.62	739	896	3	138	3.4e-27	76	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918280005	996	66.5	251	555	128	389	1.1e-78	260.1	COG0642	Signal transduction histidine kinase	336
2918280006	287	70.9	4	242	12	223	2.8e-21	67.6	COG5285	Ectoine hydroxylase-related dioxygenase, phytanoyl-CoA dioxygenase (PhyH) family	299
2918280009	141	93.79	1	141	5	140	4.4e-42	138.1	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
2918280010	177	96.17	3	175	8	183	2.5e-47	155.7	COG2032	Cu/Zn superoxide dismutase	179
2918280011	482	81.73	1	481	29	453	0.0e+00	509.3	COG0513	Superfamily II DNA and RNA helicase	513
2918280012	201	98.6	1	201	2	213	2.8e-47	156	COG0625	Glutathione S-transferase	211
2918280013	143	96.38	6	143	5	137	9.3e-64	208.2	COG3565	Predicted dioxygenase of extradiol dioxygenase family	138
2918280016	601	62.84	371	593	14	128	3.1e-22	73.3	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2918280016	601	91.05	13	287	17	250	1.5e-53	175.4	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
2918280017	204	94.35	5	180	6	172	1.8e-54	178.4	COG0663	Carbonic anhydrase or acetyltransferase, isoleucine patch superfamily	176
2918280018	558	81.63	85	530	39	429	8.5e-43	140.7	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918280019	169	26.13	1	168	52	207	5.7e-25	82.6	COG0369	Sulfite reductase, alpha subunit (flavoprotein)	587
2918280020	263	99.25	1	260	3	265	3.0e-80	264	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918280021	516	32.22	364	513	164	269	5.9e-124	70.8	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
2918280021	516	88.45	6	326	4	294	5.9e-124	335.8	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
2918280022	145	91.49	2	141	8	136	1.2e-27	90.9	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
2918280023	402	100	1	402	1	394	0.0e+00	468.3	COG0183	Acetyl-CoA acetyltransferase	392
2918280024	436	96.35	2	436	14	435	0.0e+00	532.8	COG1541	Phenylacetate-coenzyme A ligase PaaK, adenylate-forming domain family	438
2918280025	552	97.46	24	408	2	384	1.7e-66	219.6	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2918280027	704	94.04	7	663	3	649	0.0e+00	469.7	COG3345	Alpha-galactosidase	687
2918280030	536	97.58	1	536	9	572	4.4e-103	340.8	COG0747	ABC-type transport system, periplasmic component	556
2918280031	348	96.86	15	348	8	315	1.9e-111	367	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2918280032	298	94.63	8	298	14	295	2.5e-104	343	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2918280033	282	85.54	6	281	1	278	9.3e-108	354.6	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
2918280034	258	98.04	1	250	3	252	2.1e-94	310.3	COG1124	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	252
2918280035	208	99.04	1	205	1	206	3.4e-48	158.2	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
2918280036	170	86.47	27	158	14	128	3.5e-21	70.1	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918280037	374	90.63	1	374	34	420	1.0e-91	302.2	COG3508	Homogentisate 1,2-dioxygenase	427
2918280038	345	98.9	4	336	3	272	1.7e-57	189.6	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
2918280039	188	91.01	1	177	8	179	7.7e-28	92.2	COG3945	Hemerythrin-like domain	189
2918280040	354	75.73	3	94	15	92	3.8e-14	46.3	COG0633	Ferredoxin	102
2918280040	354	85.07	101	351	8	235	7.0e-43	140.4	COG1018	Ferredoxin-NADP reductase	266
2918280041	342	17.42	93	139	47	77	2.9e-04	4.8	COG1633	Rubrerythrin	176
2918280041	342	28.09	174	304	35	84	2.9e-04	8.5	COG1633	Rubrerythrin	176
2918280042	326	97.59	16	312	3	286	1.4e-79	262.1	COG3327	DNA-binding transcriptional regulator PaaX (phenylacetic acid degradation)	291
2918280043	272	84.53	5	270	9	232	1.1e-31	104.5	COG3396	1,2-phenylacetyl-CoA epoxidase, catalytic subunit	265
2918280045	388	93.72	24	388	2	344	2.0e-61	202.7	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918280046	291	99	1	290	3	300	4.2e-70	231.3	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2918280047	325	96.59	14	321	7	318	2.3e-81	268	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918280048	276	99.61	22	274	2	254	4.7e-101	331.9	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2918280049	233	98.73	1	233	3	236	3.7e-95	312.2	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2918280050	316	85.38	10	280	12	233	4.2e-29	96.3	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2918280051	212	98.14	1	212	1	211	1.7e-55	182.9	COG0625	Glutathione S-transferase	211
2918280052	296	47.18	1	147	155	296	9.0e-34	54.6	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918280052	296	64.78	94	296	100	294	9.0e-34	70.6	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918280054	238	93.95	4	238	4	236	4.7e-35	115.6	COG2129	Predicted phosphoesterase, related to the Icc protein	226
2918280056	64	84.62	1	64	11	65	1.7e-29	96.4	COG2879	Uncharacterized short protein YbdD, DUF466 family	65
2918280057	697	97.87	37	688	1	598	0.0e+00	852.9	COG1966	Carbon starvation protein CstA	575
2918280060	267	92.54	201	266	3	64	1.9e-44	96.8	COG1278	Cold shock protein, CspA family	67
2918280060	267	94.03	20	86	3	65	1.9e-44	47.6	COG1278	Cold shock protein, CspA family	67
2918280062	144	98.77	1	119	2	162	7.9e-30	98.8	COG0517	CBS domain	117
2918280063	161	68.05	2	142	6	120	1.8e-07	24.6	COG4639	Predicted kinase	168
2918280064	269	26.53	199	263	30	55	2.5e-04	7.4	COG4309	Uncharacterized conserved protein, DUF2249 family	98
2918280064	269	74.49	100	182	7	79	2.5e-04	6.2	COG4309	Uncharacterized conserved protein, DUF2249 family	98
2918280065	221	96.35	3	220	6	216	4.4e-35	115.5	COG4094	Uncharacterized membrane protein	219
2918280066	206	96.63	1	205	4	204	3.3e-42	139	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
2918280067	155	43.29	2	122	4	103	3.7e-05	17.6	COG1814	Predicted Fe2+/Mn2+ transporter, VIT1/CCC1 family	229
2918280068	252	78.89	7	244	42	198	7.5e-46	149.9	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
2918280069	618	98.65	29	610	7	590	2.3e-95	315	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
2918280072	774	79.19	388	769	80	391	1.0e-44	148.5	COG0642	Signal transduction histidine kinase	336
2918280073	241	74.59	49	234	58	239	5.5e-53	174	COG2071	Gamma-glutamyl-gamma-aminobutyrate hydrolase PuuD (putrescine degradation), contains GATase1-like domain	243
2918280075	564	66.5	127	548	128	389	1.2e-51	171.4	COG0642	Signal transduction histidine kinase	336
2918280076	273	94.68	1	273	11	277	9.9e-96	314.6	COG0656	Aldo/keto reductase, related to diketogulonate reductase	280
2918280077	976	64.97	471	838	134	389	1.6e-62	207.1	COG0642	Signal transduction histidine kinase	336
2918280077	976	89.47	852	976	8	126	7.6e-19	60.4	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918280079	318	89.55	1	318	9	308	2.1e-51	169.9	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918280080	262	96.51	7	262	8	256	4.5e-68	224	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2918280081	262	97.61	1	257	3	247	1.3e-98	324	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2918280084	75	27.65	2	72	48	94	2.3e-02	9.2	COG4803	Uncharacterized membrane protein	170
2918280086	362	87.95	8	362	37	357	2.7e-116	383.2	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
2918280088	767	85.28	190	614	56	391	1.9e-57	190.4	COG0642	Signal transduction histidine kinase	336
2918280088	767	93.98	627	760	5	129	1.2e-18	60.6	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918280089	317	34.1	66	159	20	93	4.0e-12	10.7	COG3143	Chemotaxis regulator CheZ, phosphatase of CheY~P	217
2918280089	317	43.32	138	255	122	215	4.0e-12	28.9	COG3143	Chemotaxis regulator CheZ, phosphatase of CheY~P	217
2918280090	423	31.08	124	231	121	198	4.3e-66	61.2	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2918280090	423	37.05	4	132	107	199	4.3e-66	70.5	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2918280090	423	55.78	266	423	101	240	4.3e-66	95.6	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2918280091	637	79.1	383	629	41	233	9.5e-51	167.3	COG2114	Adenylate cyclase, class 3	227
2918280092	480	91.23	22	480	42	478	0.0e+00	433.8	COG4784	Putative Zn-dependent protease	479
2918280093	267	72.68	9	165	46	186	7.1e-24	78.2	COG1525	Endonuclease YncB, thermonuclease family	192
2918280094	316	91.19	14	315	10	278	2.6e-41	136.6	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918280095	66	89.23	1	65	1	58	7.5e-24	78.7	COG0291	Ribosomal protein L35	65
2918280096	123	99.15	1	118	1	117	5.4e-54	176	COG0292	Ribosomal protein L20	118
2918280097	355	98.52	1	338	6	337	1.1e-127	420.7	COG0016	Phenylalanyl-tRNA synthetase alpha subunit	335
2918280098	803	6.13	1	55	268	307	0.0e+00	.4	COG0072	Phenylalanyl-tRNA synthetase beta subunit	650
2918280098	803	100	143	802	1	652	0.0e+00	635.5	COG0072	Phenylalanyl-tRNA synthetase beta subunit	650
2918280099	176	87.97	50	175	5	121	3.6e-14	47.2	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918280101	530	30.27	20	162	7	118	3.7e-65	22.7	COG3437	Response regulator c-di-GMP phosphodiesterase, RpfG family, contains REC and HD-GYP domains	360
2918280101	530	96.22	119	529	2	357	3.7e-65	194.9	COG3437	Response regulator c-di-GMP phosphodiesterase, RpfG family, contains REC and HD-GYP domains	360
2918280103	801	72.84	399	801	101	387	1.0e-70	234	COG0642	Signal transduction histidine kinase	336
2918280104	111	88.03	1	111	11	113	8.4e-18	59	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
2918280105	459	88.64	39	297	28	261	4.0e-60	197.8	COG3455	Type VI protein secretion system component VasF	262
2918280106	654	51.13	17	649	48	656	0.0e+00	479.3	COG3523	Type VI protein secretion system component VasK	1188
2918280107	212	60.35	4	207	7	143	3.2e-36	118.4	COG3913	Uncharacterized protein	227
2918280108	342	43.71	115	325	64	188	1.3e-10	35.2	COG2230	Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases	283
2918280109	196	81.98	37	182	17	157	3.6e-13	44.3	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2918280110	211	68.5	3	196	20	193	7.4e-42	138.5	COG0847	DNA polymerase III, epsilon subunit or related 3'-5' exonuclease	243
2918280111	195	71.36	17	194	54	195	1.6e-34	114.5	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
2918280112	341	98.49	1	338	2	328	1.2e-90	298.6	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
2918280113	169	81.92	11	169	14	158	7.0e-36	117.8	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
2918280114	427	98.94	46	425	2	376	1.1e-117	387.4	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
2918280115	304	95.68	14	303	9	296	7.0e-50	164.4	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918280117	698	83.53	283	692	69	423	1.6e-58	191.3	COG0840	Methyl-accepting chemotaxis protein	408
2918280118	409	96.72	6	391	4	357	1.2e-36	121	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918280120	642	99.17	16	642	3	599	0.0e+00	759.1	COG0514	Superfamily II DNA helicase RecQ	590
2918280121	147	72.09	10	146	17	140	3.6e-23	76.9	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2918280122	149	67.38	1	143	30	155	2.2e-23	77.8	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
2918280123	412	97.53	7	412	11	405	0.0e+00	488.5	COG1364	N-acetylglutamate synthase (N-acetylornithine aminotransferase)	404
2918280124	319	93.85	8	295	3	307	2.1e-42	139.3	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
2918280125	916	99.76	2	909	3	840	0.0e+00	1279.9	COG0653	Preprotein translocase subunit SecA (ATPase, RNA helicase)	822
2918280126	142	97.71	1	135	3	130	5.1e-45	147.7	COG1970	Large-conductance mechanosensitive channel	130
2918280127	502	78.27	10	485	6	412	0.0e+00	486	COG0513	Superfamily II DNA and RNA helicase	513
2918280128	331	96.25	14	330	6	313	7.6e-62	203.5	COG1270	Cobalamin biosynthesis protein CobD/CbiB	320
2918280129	187	58.48	21	186	84	276	2.8e-28	90.7	COG0666	Ankyrin repeat	235
2918280132	256	92.8	23	256	7	225	1.7e-38	127	COG2836	Sulfite exporter TauE/SafE	232
2918280133	294	72.76	5	276	45	247	4.9e-12	41	COG0500	SAM-dependent methyltransferase	257
2918280134	88	95.51	1	87	1	85	1.2e-16	55.2	COG1987	Flagellar biosynthesis protein FliQ	89
2918280135	248	98.21	8	246	4	223	1.0e-63	209.5	COG1040	Predicted amidophosphoribosyltransferases	225
2918280136	87	97.5	2	80	2	79	8.5e-28	91.1	COG0695	Glutaredoxin	80
2918280137	278	97.48	3	276	2	272	3.0e-64	211.2	COG0388	Predicted amidohydrolase	274
2918280138	198	50.18	4	194	47	186	1.4e-09	33.2	COG0500	SAM-dependent methyltransferase	257
2918280139	170	43.66	1	78	1	62	2.7e-44	55.3	COG5319	Uncharacterized protein	142
2918280139	170	64.79	65	170	48	139	2.7e-44	89.3	COG5319	Uncharacterized protein	142
2918280140	100	95.1	1	100	4	100	9.4e-39	126.2	COG3162	Uncharacterized membrane protein, DUF485 family	102
2918280141	570	99.63	34	562	2	535	0.0e+00	660.9	COG4147	Na+(or H+)/acetate symporter ActP	529
2918280142	610	98.85	2	609	7	609	0.0e+00	518	COG2905	Signal-transduction protein containing cAMP-binding, CBS, and nucleotidyltransferase domains	610
2918280144	547	97.37	286	544	4	225	3.3e-57	187.3	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
2918280145	367	96.24	6	359	3	335	2.9e-124	409	COG0182	Methylthioribose-1-phosphate isomerase (methionine salvage pathway), a paralog of eIF-2B alpha subunit	346
2918280146	441	67.49	24	305	19	265	1.2e-07	24.6	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918280147	896	99.43	8	896	4	868	0.0e+00	1338.7	COG1048	Aconitase A	861
2918280149	146	87.42	1	145	9	140	1.6e-33	110.2	COG4704	Uncharacterized conserved protein, DUF2141 family	151
2918280151	76	34.12	4	41	5	33	3.4e-09	15.6	COG5568	Uncharacterized protein	85
2918280151	76	45.88	36	76	47	85	3.4e-09	15.3	COG5568	Uncharacterized protein	85
2918280152	159	87.67	2	135	19	146	6.6e-36	117.9	COG0071	Molecular chaperone IbpA, HSP20 family	146
2918280153	372	86.74	1	372	1	373	3.1e-93	307.3	COG0579	L-2-hydroxyglutarate oxidase LhgO	429
2918280154	140	90.65	2	134	11	136	1.1e-27	91.3	COG2246	Putative flippase GtrA (transmembrane translocase of bactoprenol-linked glucose)	139
2918280155	354	92.48	8	312	3	334	1.0e-34	115.5	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
2918280156	893	67.51	94	587	127	392	2.0e-75	248	COG0642	Signal transduction histidine kinase	336
2918280156	893	73.6	764	886	13	104	2.6e-03	11.5	COG2198	HPt (histidine-containing phosphotransfer) domain	122
2918280156	893	91.73	601	729	7	128	6.4e-35	114.2	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918280157	981	60.19	731	919	1	127	4.7e-17	56.1	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918280157	981	77.16	362	714	87	390	1.4e-77	256.6	COG0642	Signal transduction histidine kinase	336
2918280158	1235	29.75	81	409	138	234	1.8e-01	8.1	COG2203	GAF domain	175
2918280158	1235	49.14	891	1023	2	115	1.6e-46	83.6	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918280158	1235	51.29	737	873	3	121	1.6e-46	67.2	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918280158	1235	64.97	415	718	129	384	1.1e-75	250.4	COG0642	Signal transduction histidine kinase	336
2918280158	1235	78.4	1033	1171	8	105	5.1e-07	23.1	COG2198	HPt (histidine-containing phosphotransfer) domain	122
2918280159	306	69.2	1	302	132	432	2.3e-104	344.1	COG3706	Two-component response regulator, PleD family, consists of two REC domains and a diguanylate cyclase (GGDEF) domain	435
2918280160	406	98.28	26	401	5	404	1.4e-67	221.8	COG0303	Molybdopterin biosynthesis enzyme	404
2918280161	652	92.83	440	651	2	208	1.4e-51	169.1	COG1910	Periplasmic molybdate-binding protein/domain	223
2918280161	652	97.54	17	432	7	403	4.2e-123	405.3	COG0303	Molybdopterin biosynthesis enzyme	404
2918280162	296	96.43	10	282	11	280	2.0e-86	284.4	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
2918280165	130	99.22	1	129	1	128	5.1e-20	66.6	COG4530	Uncharacterized protein	129
2918280166	593	97.8	26	593	12	544	0.0e+00	629.2	COG0405	Gamma-glutamyltranspeptidase	539
2918280167	445	97.91	4	442	9	429	0.0e+00	432.9	COG0128	5-enolpyruvylshikimate-3-phosphate synthase	428
2918280168	220	95.98	1	215	5	219	2.3e-63	207.5	COG0283	Cytidylate kinase	222
2918280169	568	99.45	10	559	2	548	0.0e+00	738.9	COG0539	Ribosomal protein S1	541
2918280170	272	90.31	5	271	20	280	8.1e-35	115	COG5473	Uncharacterized membrane protein	290
2918280171	94	96.81	1	94	2	92	5.4e-35	114.2	COG0776	Bacterial nucleoid DNA-binding protein	94
2918280172	126	69.39	1	79	26	93	1.3e-07	25.8	COG5416	Uncharacterized integral membrane protein	98
2918280173	328	96.06	1	327	4	320	6.4e-82	269	COG2423	Ornithine cyclodeaminase/archaeal alanine dehydrogenase, mu-crystallin family	330
2918280174	380	93.04	1	371	6	366	5.2e-53	175.2	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918280176	137	64.1	1	137	62	186	1.8e-20	68	COG3861	Stress response protein YsnF (function unknown)	195
2918280177	346	63.08	141	331	59	181	2.6e-11	36	COG3861	Stress response protein YsnF (function unknown)	195
2918280178	239	93.75	1	239	12	236	8.7e-67	219.6	COG0284	Orotidine-5'-phosphate decarboxylase	240
2918280179	214	98.09	2	214	2	206	1.5e-62	205.8	COG0135	Phosphoribosylanthranilate isomerase	208
2918280180	312	89.62	67	286	17	180	3.2e-46	152	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2918280181	217	98.1	8	217	5	210	5.5e-83	272.3	COG0035	Uracil phosphoribosyltransferase	210
2918280182	576	97.61	28	573	10	540	4.9e-129	425.6	COG1178	ABC-type Fe3+ transport system, permease component	540
2918280183	282	98.93	3	282	3	279	4.3e-93	306.4	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
2918280184	342	99.67	43	342	2	301	1.5e-67	222.5	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
2918280185	170	92.82	1	169	11	178	2.6e-08	26.6	COG5342	Invasion protein IalB, involved in pathogenesis	181
2918280186	623	98.06	1	611	13	620	0.0e+00	793.5	COG4547	Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide:5, 6-dimethylbenzimidazole phosphorib...	620
2918280188	334	87.27	26	326	3	290	7.7e-55	180.8	COG0714	MoxR-like ATPase	329
2918280190	90	91.11	1	90	6	87	2.2e-31	102.7	COG0271	Stress-induced morphogen (activity unknown)	90
2918280191	166	68.63	12	112	16	85	2.7e-15	50.2	COG4321	Predicted DNA-binding protein, contains Ribbon-helix-helix (RHH) domain	102
2918280194	152	92.02	4	123	13	162	3.2e-27	90.3	COG0517	CBS domain	117
2918280195	375	98.89	7	375	3	358	1.4e-129	427	COG0337	3-dehydroquinate synthetase	360
2918280196	212	97.09	15	186	3	169	2.1e-55	181.8	COG0703	Shikimate kinase	172
2918280199	333	97.67	20	325	8	300	4.4e-105	345.7	COG4974	Site-specific recombinase XerD	300
2918280200	534	96.88	2	533	17	574	0.0e+00	568.6	COG2225	Malate synthase	545
2918280201	391	82.34	65	391	65	367	3.6e-41	135.8	COG2208	Serine phosphatase RsbU, regulator of sigma subunit	367
2918280202	412	93.23	23	187	6	129	1.0e-35	116.5	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918280203	248	19.18	180	238	64	91	2.3e-07	6.1	COG2172	Anti-sigma regulatory factor (Ser/Thr protein kinase)	146
2918280203	248	31.51	96	167	13	58	2.3e-07	17	COG2172	Anti-sigma regulatory factor (Ser/Thr protein kinase)	146
2918280204	101	81.2	3	101	10	104	2.2e-17	57.5	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
2918280205	373	65.41	36	332	147	424	2.4e-31	103.1	COG0840	Methyl-accepting chemotaxis protein	408
2918280206	353	98.58	4	350	2	348	3.6e-126	415.6	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
2918280207	208	95.73	19	182	2	158	3.9e-50	164.1	COG1871	Chemotaxis receptor (MCP) glutamine deamidase CheD	164
2918280208	296	98.52	25	296	2	267	4.3e-83	273.2	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
2918280209	853	24	48	416	43	144	4.3e-118	27.8	COG0840	Methyl-accepting chemotaxis protein	408
2918280209	853	90.59	426	839	39	423	4.3e-118	366.5	COG0840	Methyl-accepting chemotaxis protein	408
2918280210	181	87.88	9	169	12	156	1.2e-44	146.1	COG0835	Chemotaxis signal transduction protein	165
2918280211	744	98.54	1	733	5	747	0.0e+00	687.9	COG0643	Chemotaxis protein histidine kinase CheA	716
2918280212	121	49.14	3	120	2	115	3.4e-35	116	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918280213	103	70.09	4	98	17	98	3.5e-10	34.2	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
2918280214	911	63.64	582	909	126	356	4.5e-27	89.2	COG3852	Signal transduction histidine kinase, nitrogen specific	363
2918280214	911	96.8	4	550	6	489	5.7e-84	276.7	COG0591	Na+/proline symporter	493
2918280216	730	35.95	45	279	99	185	1.7e-07	24.6	COG2202	PAS domain	232
2918280216	730	75.2	502	728	14	204	3.0e-50	165.4	COG0847	DNA polymerase III, epsilon subunit or related 3'-5' exonuclease	243
2918280217	130	51.72	3	129	2	121	3.1e-40	132.5	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918280218	362	57.98	30	361	99	236	4.2e-09	15.2	COG3147	Cell division protein DedD (periplasmic protein involved in septation)	226
2918280219	309	94.03	9	304	13	264	8.6e-53	173.9	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
2918280220	187	98.33	5	183	2	178	2.6e-60	198.4	COG2917	Intracellular septation protein A	180
2918280221	350	86.97	44	350	43	329	1.8e-42	139.8	COG3528	Uncharacterized protein	330
2918280222	128	99.23	1	128	1	129	2.6e-33	109.3	COG3744	PIN domain nuclease, a component of toxin-antitoxin system (PIN domain)	130
2918280223	76	80.95	2	76	3	70	2.1e-22	73.9	COG4118	Antitoxin component of toxin-antitoxin stability system, DNA-binding transcriptional repressor	84
2918280224	567	90.12	32	562	41	423	3.6e-62	205	COG0840	Methyl-accepting chemotaxis protein	408
2918280225	508	85.23	211	487	35	236	1.6e-59	195.5	COG0775	Nucleoside phosphorylase	234
2918280226	434	90.56	10	429	34	359	6.7e-120	395.2	COG0552	Signal recognition particle GTPase	340
2918280227	419	97.96	6	419	6	437	3.5e-127	419.5	COG0621	tRNA A37 methylthiotransferase MiaB	437
2918280228	277	99.26	3	272	2	270	3.8e-92	303.1	COG0253	Diaminopimelate epimerase	272
2918280229	103	15.17	2	74	177	235	4.1e-03	10.6	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
2918280230	88	48.98	1	84	20	67	3.1e-04	15.6	COG4829	Muconolactone delta-isomerase	98
2918280231	144	89.93	12	144	12	136	1.9e-19	64.5	COG2246	Putative flippase GtrA (transmembrane translocase of bactoprenol-linked glucose)	139
2918280232	334	48.47	19	271	3	176	1.2e-14	49.9	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
2918280234	204	97.41	1	202	1	188	2.7e-81	266.5	COG0066	3-isopropylmalate dehydratase small subunit	191
2918280235	371	98.85	3	369	3	346	1.3e-123	406.9	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
2918280236	97	64.86	1	59	15	62	5.4e-23	41.9	COG3729	General stress protein YciG, contains tandem KGG domains	73
2918280236	97	64.86	37	92	23	70	5.4e-23	45.9	COG3729	General stress protein YciG, contains tandem KGG domains	73
2918280238	291	98.25	10	289	1	280	8.0e-91	298.6	COG2301	Citrate lyase beta subunit	283
2918280240	286	99.64	2	286	1	280	5.6e-96	315.6	COG2240	Pyridoxal/pyridoxine/pyridoxamine kinase	281
2918280241	192	91.71	1	188	17	204	5.2e-61	200.4	COG1611	Predicted Rossmann fold nucleotide-binding protein	205
2918280242	161	48.85	42	144	45	108	8.4e-10	32.1	COG1917	Cupin domain protein related to quercetin dioxygenase	131
2918280243	283	96.91	1	283	7	320	1.2e-83	275.7	COG0627	S-formylglutathione hydrolase FrmB	316
2918280244	372	99.45	2	370	2	365	0.0e+00	568.7	COG1062	Zn-dependent alcohol dehydrogenase	366
2918280246	243	99.05	28	243	2	210	1.6e-45	149.8	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918280247	759	50.63	418	475	23	62	4.6e+00	3.8	COG3074	Cell division protein ZapB, interacts with FtsZ	79
2918280247	759	98.89	13	278	2	268	2.1e-81	267	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
2918280250	662	67.26	177	526	127	391	3.1e-60	199.6	COG0642	Signal transduction histidine kinase	336
2918280251	373	89.91	22	365	18	222	2.2e-50	163.7	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
2918280252	382	96.51	1	381	13	371	1.7e-130	430.1	COG1485	Predicted ATPase	367
2918280254	456	89.62	237	456	18	181	5.2e-51	166.8	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2918280255	745	63.96	263	727	137	388	5.8e-81	266.2	COG0642	Signal transduction histidine kinase	336
2918280257	208	48.28	26	193	100	211	1.1e-13	46.4	COG0671	Membrane-associated phospholipid phosphatase	232
2918280258	930	98.27	50	929	10	861	0.0e+00	966.9	COG2844	UTP:GlnB (protein PII) uridylyltransferase	867
2918280259	713	48.35	584	711	11	98	1.0e-09	32.3	COG4567	Two-component response regulator, ActR/RegA family, consists of REC and Fis-type HTH domains	182
2918280259	713	85.03	143	567	56	390	2.4e-52	173.7	COG0642	Signal transduction histidine kinase	336
2918280261	582	65.91	84	575	208	644	5.4e-97	319.9	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2918280262	279	72.33	140	279	42	156	4.5e-23	65.4	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2918280262	279	76.73	1	127	6	127	4.5e-23	15.8	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2918280264	1256	15.71	1141	1251	413	500	1.3e-12	42.2	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918280264	1256	79.46	369	1153	13	457	1.3e-12	11.5	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918280265	169	58.64	9	140	60	154	1.5e-10	36.2	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2918280267	390	17.32	280	386	320	403	6.8e-39	4.5	COG4783	Putative Zn-dependent protease, contains TPR repeats	484
2918280267	390	46.8	47	281	54	280	6.8e-39	125.1	COG4783	Putative Zn-dependent protease, contains TPR repeats	484
2918280269	885	98.85	1	876	8	864	0.0e+00	922.2	COG0308	Aminopeptidase N	859
2918280270	126	85.29	1	126	16	131	7.0e-45	147.1	COG3474	Cytochrome c2	135
2918280271	233	98.63	1	147	1	144	2.3e-51	167.9	COG3427	Carbon monoxide dehydrogenase subunit G	146
2918280273	171	95.65	1	158	1	154	2.6e-50	164.7	COG0801	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase	160
2918280274	133	75.21	33	132	28	118	6.0e-10	33.8	COG1539	Dihydroneopterin aldolase	121
2918280276	122	92.48	1	122	5	127	5.1e-20	66.4	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918280277	784	82.74	209	647	64	389	1.2e-53	177.9	COG0642	Signal transduction histidine kinase	336
2918280280	288	57.23	1	136	5	95	2.0e-19	14.1	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2918280280	288	58.49	105	288	64	156	2.0e-19	55.6	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2918280281	512	91.18	339	511	2	156	4.1e-44	145.2	COG0645	Predicted kinase	170
2918280281	512	91.39	7	336	20	327	2.6e-100	329.9	COG2187	Aminoglycoside phosphotransferase family enzyme	337
2918280283	207	71.3	49	161	28	109	5.2e-07	24	COG5442	Flagellar biosynthesis regulator FlaF	115
2918280284	313	97.34	14	301	5	297	8.0e-46	151	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918280285	152	61.19	1	148	104	267	2.8e-35	116.8	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918280286	99	36.94	1	99	4	102	1.3e-24	82	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918280287	315	95.4	6	315	13	323	1.9e-73	241.9	COG3503	Uncharacterized membrane protein	323
2918280288	344	97.03	29	327	3	296	4.1e-82	270.3	COG1295	Uncharacterized membrane protein, BrkB/YihY/UPF0761 family (not an RNase)	303
2918280290	215	77.73	3	213	18	216	2.0e-50	165.8	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
2918280291	160	57.89	19	159	50	170	4.5e-07	24.2	COG0406	Broad specificity phosphatase PhoE	208
2918280292	370	94.23	2	367	8	350	1.6e-58	193.2	COG5330	Uncharacterized conserved protein, DUF2336 family	364
2918280294	208	92.68	1	197	15	204	3.4e-49	161.8	COG3218	ABC-type uncharacterized transport system, auxiliary component	205
2918280295	319	81.35	1	316	1	301	1.3e-46	153.9	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2918280296	262	95.06	6	262	6	255	5.2e-103	338.4	COG1127	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, ATPase component MlaF	263
2918280297	385	68.38	16	107	16	95	7.3e-09	28.6	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
2918280297	385	95.51	117	385	9	263	6.4e-83	272.4	COG0767	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, permease component MlaE	267
2918280298	175	89.39	1	174	6	165	4.3e-56	183.6	COG0503	Adenine/guanine phosphoribosyltransferase or related PRPP-binding protein	179
2918280299	175	82.28	1	172	26	155	4.0e-24	74.4	COG5490	Uncharacterized protein	158
2918280300	252	95.29	1	246	1	243	4.4e-46	151.6	COG3484	Predicted proteasome-type protease	255
2918280302	417	93.89	1	377	20	388	3.5e-112	369.9	COG1686	D-alanyl-D-alanine carboxypeptidase	389
2918280303	377	83.58	2	377	67	468	2.2e-87	286.3	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
2918280304	549	95.93	13	548	21	562	9.4e-102	336.1	COG2936	Predicted acyl esterase	563
2918280305	256	59	4	248	60	272	5.6e-12	40	COG3177	Fic family protein	348
2918280306	140	93.06	2	140	2	135	3.0e-31	102.9	COG2703	Hemerythrin	144
2918280307	422	56.35	124	360	87	197	2.6e-28	94.3	COG2823	Osmotically-inducible protein OsmY, contains BON domain	196
2918280308	462	97.13	1	449	4	443	0.0e+00	707.9	COG4303	Ethanolamine ammonia-lyase, large subunit	453
2918280309	251	79.93	2	242	59	293	3.8e-74	244.1	COG4302	Ethanolamine ammonia-lyase, small subunit	294
2918280310	127	93.98	1	127	5	129	5.4e-23	76	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918280311	158	99.36	1	156	1	155	1.4e-47	156.1	COG2954	CYTH domain, found in class IV adenylate cyclase and various triphosphatases	156
2918280315	594	95.44	16	582	4	568	0.0e+00	493.2	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
2918280319	162	98.18	1	162	4	165	5.5e-58	190.4	COG1666	Uncharacterized conserved protein YajQ, UPF0234 family	165
2918280323	143	98.77	2	119	2	162	8.0e-27	88.9	COG0517	CBS domain	117
2918280324	136	91.67	2	136	2	133	5.6e-35	115	COG2703	Hemerythrin	144
2918280327	334	97.5	14	324	4	315	2.5e-117	386.2	COG4608	ABC-type oligopeptide transport system, ATPase component	309
2918280328	330	98.46	3	317	1	320	4.8e-129	424.5	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
2918280329	304	95.3	11	304	13	296	4.5e-102	335.5	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2918280330	336	99.69	1	336	1	317	2.8e-127	419.1	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2918280331	533	95.5	1	532	18	569	0.0e+00	479.9	COG0747	ABC-type transport system, periplasmic component	556
2918280332	311	95.68	6	304	9	296	3.4e-49	162.3	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918280333	566	98.4	6	566	4	555	0.0e+00	980.9	COG2987	Urocanate hydratase	561
2918280334	400	94.1	5	400	16	398	0.0e+00	441.7	COG1228	Imidazolonepropionase or related amidohydrolase	406
2918280335	449	98.82	1	442	5	423	2.3e-89	294.3	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
2918280336	284	98.44	5	281	4	256	6.8e-46	150.8	COG3394	Predicted glycoside hydrolase or deacetylase ChbG, UPF0249 family	257
2918280338	257	69.89	8	252	45	239	3.8e-10	34.9	COG0500	SAM-dependent methyltransferase	257
2918280339	132	41.73	65	132	12	69	7.6e-23	38.1	COG2246	Putative flippase GtrA (transmembrane translocase of bactoprenol-linked glucose)	139
2918280339	132	45.32	2	71	9	71	7.6e-23	42.4	COG2246	Putative flippase GtrA (transmembrane translocase of bactoprenol-linked glucose)	139
2918280340	545	97.64	30	545	4	542	0.0e+00	435.8	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
2918280341	179	88.72	37	171	10	127	3.6e-22	73.3	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918280343	270	90.98	86	260	7	127	7.6e-18	58.3	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918280344	288	98.95	1	288	3	286	3.0e-129	425.3	COG0788	Formyltetrahydrofolate hydrolase	287
2918280347	266	72.56	17	262	69	261	2.9e-66	218	COG0860	N-acetylmuramoyl-L-alanine amidase	231
2918280348	178	89.34	1	178	19	194	2.6e-33	110.5	COG2823	Osmotically-inducible protein OsmY, contains BON domain	196
2918280350	339	84	15	339	46	339	2.1e-82	271.8	COG3768	Uncharacterized membrane protein YcjF, UPF0283 family	350
2918280351	470	97.39	13	470	12	459	0.0e+00	507.6	COG3106	Predicted ATPase, YcjX-like family	467
2918280352	334	98.32	35	331	3	295	1.3e-109	360.4	COG1159	GTPase Era, involved in 16S rRNA processing	298
2918280353	241	94.92	1	240	9	232	1.4e-63	208.8	COG0571	dsRNA-specific ribonuclease	235
2918280354	256	73.86	3	228	7	136	4.7e-31	101.8	COG0681	Signal peptidase I	166
2918280355	151	98.43	1	138	1	125	9.5e-39	127	COG0736	Phosphopantetheinyl transferase (holo-ACP synthase)	127
2918280356	244	98.77	5	244	2	241	7.9e-98	321.2	COG0854	Pyridoxine 5'-phosphate synthase PdxJ	243
2918280357	136	95.74	3	135	2	136	7.1e-39	127.4	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
2918280359	722	99.17	1	719	6	723	0.0e+00	885.3	COG0317	(p)ppGpp synthase/hydrolase, HD superfamily	701
2918280360	148	95.95	1	72	1	71	7.3e-23	74.7	COG1758	DNA-directed RNA polymerase, subunit K/omega	74
2918280361	197	90.1	1	173	11	183	3.4e-48	158.9	COG1432	Uncharacterized conserved protein, LabA/DUF88 family	181
2918280362	338	87.65	3	329	40	337	6.2e-49	161.5	COG4246	Uncharacterized protein	340
2918280363	230	90.79	18	230	15	221	1.0e-41	137.1	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
2918280364	121	99.17	1	118	1	120	2.3e-10	33.6	COG1433	Predicted Fe-Mo cluster-binding protein, NifX family	121
2918280365	173	75.19	27	173	15	114	5.1e-17	56.6	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918280366	301	92.31	16	272	9	248	2.0e-31	103.9	COG5010	Flp pilus assembly protein TadD, contains TPR repeats	257
2918280367	280	76.51	3	250	42	256	9.4e-54	177.3	COG3000	Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily	271
2918280368	156	93.68	1	154	11	173	1.5e-09	32.4	COG5430	Spore coat protein U (SCPU) domain, function unknown	174
2918280369	243	84.1	1	239	13	213	7.5e-21	69	COG3121	P pilus assembly protein, chaperone PapD	235
2918280370	828	88.66	2	820	63	805	2.3e-63	208.5	COG3188	Outer membrane usher protein FimD/PapC	835
2918280371	304	67.82	9	148	52	169	7.8e-07	11.3	COG5430	Spore coat protein U (SCPU) domain, function unknown	174
2918280371	304	82.76	157	302	30	173	7.8e-07	8.9	COG5430	Spore coat protein U (SCPU) domain, function unknown	174
2918280372	157	56.9	45	155	75	173	2.2e-03	11.7	COG5430	Spore coat protein U (SCPU) domain, function unknown	174
2918280373	360	94.52	18	360	9	336	8.0e-64	210.4	COG3239	Fatty acid desaturase	343
2918280374	418	15.51	292	413	260	353	6.3e-60	35.5	COG0443	Molecular chaperone DnaK (HSP70)	579
2918280374	418	49.83	1	299	7	308	6.3e-60	161	COG0443	Molecular chaperone DnaK (HSP70)	579
2918280375	191	98.42	1	190	1	187	4.5e-51	167.7	COG1971	Putative Mn2+ efflux pump MntP	190
2918280376	448	92.08	10	360	13	291	1.7e-59	195.8	COG1295	Uncharacterized membrane protein, BrkB/YihY/UPF0761 family (not an RNase)	303
2918280377	282	98.07	5	264	3	256	2.4e-119	391.9	COG0623	Enoyl-[acyl-carrier-protein] reductase (NADH)	259
2918280379	358	95.95	2	357	2	356	0.0e+00	530.7	COG0082	Chorismate synthase	369
2918280380	190	24.86	4	79	21	65	9.4e-07	11.3	COG5342	Invasion protein IalB, involved in pathogenesis	181
2918280380	190	25.41	123	182	135	180	9.4e-07	10.3	COG5342	Invasion protein IalB, involved in pathogenesis	181
2918280382	369	87.97	18	293	7	123	1.1e-22	74.1	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918280383	190	82.26	10	183	33	185	3.6e-35	116.3	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
2918280384	581	43.44	56	287	145	283	1.5e-88	36.6	COG0616	Periplasmic serine protease, ClpP class	317
2918280384	581	71.25	268	572	57	284	1.5e-88	254.7	COG0616	Periplasmic serine protease, ClpP class	317
2918280387	219	23.57	6	212	355	486	1.8e-13	40.8	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918280389	1011	49.37	678	747	23	61	2.3e-01	5.6	COG3074	Cell division protein ZapB, interacts with FtsZ	79
2918280389	1011	97.78	239	503	3	266	3.9e-78	256.2	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
2918280390	842	48.9	709	837	5	93	1.3e-08	28.7	COG4567	Two-component response regulator, ActR/RegA family, consists of REC and Fis-type HTH domains	182
2918280390	842	69.8	293	697	116	390	4.3e-57	189.2	COG0642	Signal transduction histidine kinase	336
2918280392	206	97.89	7	198	3	188	2.2e-85	279.9	COG3005	Tetraheme cytochrome c subunit of nitrate or TMAO reductase	190
2918280393	153	87.1	1	147	19	153	7.8e-51	166.8	COG3043	Nitrate reductase cytochrome c-type subunit	155
2918280394	839	99.88	2	831	1	809	0.0e+00	720.1	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
2918280395	94	88.3	1	92	5	87	8.5e-22	71.6	COG3062	Cytoplasmic chaperone NapD for the signal peptide of periplasmic nitrate reductase NapAB	94
2918280396	168	21.77	125	166	35	61	1.5e-17	27.6	COG1145	Ferredoxin	99
2918280396	168	59.68	5	102	37	110	1.5e-17	36.5	COG1145	Ferredoxin	99
2918280397	57	74.19	2	57	12	57	1.6e-21	70.7	COG4459	Periplasmic nitrate reductase system, NapE component	62
2918280398	266	97.27	1	260	4	252	1.6e-68	225.4	COG0390	ABC-type iron transport system FetAB, permease component	256
2918280399	196	89.24	3	196	16	214	2.1e-42	138.5	COG4619	ABC-type iron transport system FetAB, ATPase component	223
2918280400	510	49.87	274	508	15	205	1.2e-48	20.7	COG0477	MFS family permease	338
2918280400	510	83.55	16	304	3	322	1.2e-48	143.6	COG0477	MFS family permease	338
2918280402	366	91.92	11	364	18	381	8.5e-49	160.9	COG3213	Uncharacterized protein involved in response to NO	396
2918280403	534	99.09	17	528	6	552	0.0e+00	548.5	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
2918280404	763	6.47	462	508	594	634	2.6e-75	3.8	COG1042	Acyl-CoA synthetase (NDP forming)	598
2918280404	763	78.07	591	759	11	156	9.2e-10	32.7	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
2918280404	763	80.44	3	466	2	511	2.6e-75	242.6	COG1042	Acyl-CoA synthetase (NDP forming)	598
2918280405	79	87.65	1	79	10	80	1.9e-08	29.1	COG0236	Acyl carrier protein	80
2918280406	140	87.02	1	122	4	117	7.6e-39	127.2	COG2005	DNA-binding transcriptional regulator ModE (molybdenum-dependent)	130
2918280407	371	99.72	1	357	1	351	0.0e+00	441.3	COG4148	ABC-type molybdate transport system, ATPase component	352
2918280408	231	96.89	4	227	2	219	3.4e-81	266.4	COG4149	ABC-type molybdate transport system, permease component	225
2918280409	265	96.63	5	262	8	265	8.9e-72	236.1	COG0725	ABC-type molybdate transport system, periplasmic component	258
2918280410	218	96.36	1	218	2	213	4.0e-91	298.6	COG0036	Pentose-5-phosphate-3-epimerase	220
2918280411	227	28.32	26	218	109	187	4.9e-06	21.8	COG0500	SAM-dependent methyltransferase	257
2918280412	209	95.32	6	203	6	168	2.1e-25	82.7	COG3652	Predicted outer membrane protein	170
2918280413	85	97.56	1	82	1	80	9.3e-23	74.8	COG2261	Uncharacterized membrane protein YeaQ/YmgE, transglycosylase-associated protein family	82
2918280414	265	88.71	1	147	15	179	4.9e-18	50.8	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918280415	133	71.13	1	133	52	189	2.0e-27	90.2	COG1525	Endonuclease YncB, thermonuclease family	192
2918280416	227	89.82	2	223	21	223	7.2e-70	229.4	COG2135	Putative SOS response-associated peptidase YedK	226
2918280417	774	99.73	1	766	2	744	0.0e+00	687.8	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
2918280418	258	87.94	3	256	16	241	3.3e-59	194	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
2918280419	232	93.07	8	232	13	227	3.4e-25	83.2	COG1814	Predicted Fe2+/Mn2+ transporter, VIT1/CCC1 family	229
2918280420	168	80.25	1	148	26	155	3.8e-11	38.2	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2918280421	258	92.39	4	257	7	261	2.8e-82	270.5	COG1218	3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase	276
2918280422	265	97.76	1	265	2	263	9.0e-90	295.2	COG2833	Uncharacterized conserved protein, contains ferritin-like DUF455 domain	268
2918280424	237	91.87	11	220	3	194	4.7e-33	109.2	COG0406	Broad specificity phosphatase PhoE	208
2918280426	352	80.73	16	326	48	311	7.3e-45	148	COG3173	Predicted  kinase, aminoglycoside phosphotransferase (APT) family	321
2918280427	398	97.99	1	393	1	391	2.4e-98	324.4	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918280428	253	98.88	3	250	2	266	4.9e-70	230.7	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918280429	557	96.3	29	557	14	560	7.0e-110	362.5	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2918280430	217	49.8	6	170	49	170	4.1e-10	34	COG3904	Predicted periplasmic protein	245
2918280431	236	96.79	8	226	6	216	1.7e-44	146.4	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2918280432	300	98.67	5	300	2	298	7.4e-71	234	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918280433	359	98.56	2	359	2	344	1.5e-129	426.5	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
2918280434	935	85.29	624	935	49	332	4.6e-65	214.1	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
2918280435	604	32.51	2	188	15	146	1.2e-28	43.2	COG4252	Extracellular (periplasmic) sensor domain CHASE2 (specificity unknown)	400
2918280435	604	33.99	190	360	263	400	1.2e-28	53.8	COG4252	Extracellular (periplasmic) sensor domain CHASE2 (specificity unknown)	400
2918280435	604	77.87	337	603	51	240	2.6e-45	148.9	COG2114	Adenylate cyclase, class 3	227
2918280437	71	21.18	2	36	12	29	2.7e-06	5.5	COG5568	Uncharacterized protein	85
2918280437	71	42.35	30	71	50	85	2.7e-06	16.4	COG5568	Uncharacterized protein	85
2918280439	303	78.39	91	303	40	195	2.5e-33	110	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
2918280440	523	52.1	260	508	42	165	2.3e-09	32.1	COG3409	Peptidoglycan-binding (PGRP) domain of peptidoglycan hydrolases	185
2918280440	523	62.35	1	256	18	176	1.1e-05	19.3	COG1462	Curli biogenesis system outer membrane secretion channel CsgG	252
2918280443	498	64.22	335	497	3	142	1.0e-26	87.9	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2918280443	498	76.61	25	336	61	322	1.1e-50	167	COG0668	Small-conductance mechanosensitive channel	316
2918280444	389	90.38	2	346	7	335	1.1e-42	141.5	COG5330	Uncharacterized conserved protein, DUF2336 family	364
2918280445	172	93.23	31	163	4	127	2.1e-17	57.8	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918280446	323	97.97	33	312	2	290	3.9e-45	149.2	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918280448	103	12.97	1	102	126	214	2.9e-05	17.3	COG1289	Uncharacterized membrane protein YccC	674
2918280449	274	60.93	2	261	18	187	4.2e-18	60.8	COG0500	SAM-dependent methyltransferase	257
2918280450	1469	98.58	2	1469	20	1334	0.0e+00	489.1	COG2911	Autotransporter translocation and assembly factor TamB	1278
2918280451	638	95.52	47	638	28	603	3.9e-97	320.6	COG0729	Outer membrane translocation and assembly module TamA	594
2918280452	608	99.34	1	605	3	601	0.0e+00	969.9	COG1217	Predicted membrane GTPase involved in stress response	603
2918280453	158	95.8	1	155	5	141	5.1e-34	112	COG1764	Organic hydroperoxide reductase OsmC/OhrA	143
2918280455	59	80.6	1	59	5	58	2.5e-18	60.7	COG3237	Uncharacterized conserved protein YjbJ, UPF0337 family	67
2918280456	135	96.45	1	133	5	140	1.8e-25	84.1	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
2918280457	870	75.84	315	737	22	404	2.8e-59	195.4	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
2918280457	870	91.8	2	292	22	301	3.5e-57	188.1	COG5309	Exo-beta-1,3-glucanase,  GH17 family	305
2918280459	432	26.13	337	432	245	331	4.5e-43	43.4	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
2918280459	432	41.44	140	340	57	194	4.5e-43	100.3	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
2918280460	110	87.5	51	110	2	57	2.7e-20	66.8	COG3411	(2Fe-2S) ferredoxin	64
2918280461	266	98.73	1	265	1	234	3.2e-53	175.5	COG3416	Uncharacterized protein	233
2918280463	794	98.09	8	789	9	777	0.0e+00	958.6	COG0466	ATP-dependent Lon protease, bacterial type	782
2918280464	135	62.33	2	127	20	110	4.1e-19	63.5	COG0071	Molecular chaperone IbpA, HSP20 family	146
2918280466	81	21.35	4	71	72	128	2.4e-04	15	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
2918280468	392	37.19	1	155	2	149	1.6e-28	51.8	COG1459	Type II secretory pathway, component PulF	397
2918280468	392	44.97	192	388	218	396	1.6e-28	40.4	COG1459	Type II secretory pathway, component PulF	397
2918280471	274	81.13	148	274	28	156	1.8e-12	30.5	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2918280471	274	93.08	1	143	6	153	1.8e-12	16.1	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2918280472	407	98.36	17	384	4	363	7.3e-40	131.5	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918280475	514	74.41	57	497	130	507	1.2e-112	366.8	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
2918280477	320	77.69	1	320	25	400	3.9e-91	300.5	COG5459	Ribosomal protein RSM22 (predicted mitochondrial rRNA methylase)	484
2918280478	171	82.3	1	169	29	200	1.2e-15	53.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918280479	301	95.35	21	301	10	296	5.7e-32	105.8	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918280480	220	96.23	3	209	3	206	2.0e-45	149.5	COG3531	Predicted protein-disulfide isomerase , contains CxxC motif	212
2918280481	198	91.85	7	190	2	170	2.9e-42	139	COG0431	NAD(P)H-dependent FMN reductase	184
2918280482	303	90.82	2	300	11	287	1.2e-54	179.9	COG0053	Divalent metal cation (Fe/Co/Zn/Cd) transporter	304
2918280483	135	94.37	3	132	2	135	4.2e-11	35.7	COG1569	Predicted nucleic acid-binding protein, contains PIN domain	142
2918280484	273	96.46	12	251	4	221	1.2e-23	78.2	COG3619	Uncharacterized membrane protein YoaK, UPF0700 family	226
2918280485	730	97.85	14	728	7	735	0.0e+00	500.3	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
2918280486	151	96.79	1	151	4	154	1.3e-60	198.3	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
2918280487	219	96.3	6	217	4	211	7.1e-38	124.7	COG3806	Anti-sigma factor ChrR, cupin superfamily	216
2918280488	190	92.47	15	190	8	179	1.7e-40	133.3	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918280489	485	79.75	2	478	113	557	0.0e+00	493.1	COG3829	Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding Fis domains	560
2918280490	753	99.21	4	752	5	753	0.0e+00	1044.4	COG1882	Pyruvate-formate lyase	755
2918280491	60	76.92	2	60	16	65	1.6e-07	26	COG2879	Uncharacterized short protein YbdD, DUF466 family	65
2918280492	692	97.38	32	679	1	595	0.0e+00	768.5	COG1966	Carbon starvation protein CstA	575
2918280493	325	99.39	4	325	1	324	8.9e-111	365	COG0523	GTPase, G3E family	323
2918280494	341	58.63	19	333	170	461	7.0e-13	37.4	COG2319	WD40 repeat	466
2918280495	256	93.89	4	233	2	216	3.5e-70	230.4	COG5482	Uncharacterized protein	229
2918280496	717	97.63	10	551	12	546	0.0e+00	833.7	COG1884	Methylmalonyl-CoA mutase, N-terminal domain/subunit	548
2918280497	197	90.81	21	197	13	180	1.1e-45	149.9	COG1268	Biotin transporter BioY	184
2918280498	666	99.85	1	666	1	645	0.0e+00	910.5	COG4770	Acetyl/propionyl-CoA carboxylase, alpha subunit	645
2918280499	510	97.91	1	510	12	526	0.0e+00	748.6	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component	526
2918280500	483	78.26	1	73	5	58	4.7e-09	29.8	COG1476	DNA-binding transcriptional regulator, XRE-family HTH domain	68
2918280500	483	99.1	143	474	3	331	0.0e+00	454.9	COG3800	Predicted transcriptional regulator	332
2918280501	241	99.57	10	241	1	229	3.9e-74	243.9	COG1794	Aspartate/glutamate racemase	230
2918280502	248	98.78	3	248	2	243	2.0e-95	313.3	COG1189	Predicted rRNA methylase YqxC, contains S4 and FtsJ domains	245
2918280503	318	91.23	101	318	14	221	7.5e-51	166.9	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
2918280504	259	98.13	4	255	4	266	3.1e-48	159.1	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918280505	254	56.58	2	234	95	339	2.5e-36	115.9	COG0593	Chromosomal replication initiation ATPase DnaA	408
2918280506	356	92.78	2	351	15	348	2.2e-86	284.5	COG0628	Predicted PurR-regulated permease PerM	355
2918280507	186	88.66	1	182	14	185	1.8e-35	117.3	COG0558	Phosphatidylglycerophosphate synthase	192
2918280509	344	95.94	1	336	11	341	0.0e+00	456.6	COG0150	Phosphoribosylaminoimidazole (AIR) synthetase	345
2918280510	217	98.5	4	204	2	198	4.8e-78	255.8	COG0299	Folate-dependent phosphoribosylglycinamide formyltransferase PurN	200
2918280513	140	97.78	2	136	2	133	2.7e-59	193.4	COG0105	Nucleoside diphosphate kinase	135
2918280514	639	99.07	8	528	2	531	0.0e+00	590.4	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
2918280515	217	95.22	12	216	6	204	1.7e-37	123	COG3932	Uncharacterized conserved protein	209
2918280516	155	72.68	4	155	51	191	2.1e-30	100.2	COG3963	Phospholipid N-methyltransferase	194
2918280517	253	96.6	1	253	6	261	1.3e-50	166.5	COG0300	Short-chain dehydrogenase	265
2918280518	288	98.62	1	288	5	290	5.1e-88	289.9	COG1561	Uncharacterized conserved protein YicC, UPF0701 family	290
2918280519	201	94.87	1	192	8	192	1.4e-74	244.4	COG0194	Guanylate kinase	191
2918280520	124	22.08	27	73	70	103	4.1e-02	5.7	COG3133	Outer membrane lipoprotein SlyB	154
2918280520	124	26.62	69	118	69	109	4.1e-02	7	COG3133	Outer membrane lipoprotein SlyB	154
2918280521	357	85.19	11	165	20	157	2.0e-23	76.8	COG3666	Transposase	161
2918280524	542	75.63	163	521	93	390	5.2e-48	158.7	COG0642	Signal transduction histidine kinase	336
2918280525	483	98.96	6	483	4	481	0.0e+00	689.5	COG0064	Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit	483
2918280526	493	98.96	1	491	3	478	0.0e+00	600.4	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
2918280527	95	98.96	1	95	1	95	1.7e-31	103	COG0721	Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit	96
2918280528	168	93.58	1	164	12	186	8.7e-17	55.9	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
2918280529	178	95.74	15	159	2	136	1.9e-41	135.7	COG0816	RNase H-fold protein, predicted Holliday junction resolvase in Firmicutes and mycoplasms, involved in anti-termination at Rho-dependent terminators	141
2918280530	305	98.4	1	305	2	309	4.2e-46	151.9	COG0679	Predicted permease	311
2918280531	118	82.22	1	116	21	131	8.3e-23	75.4	COG3791	Uncharacterized conserved protein	133
2918280532	144	86.67	3	135	6	122	2.5e-29	96.3	COG3791	Uncharacterized conserved protein	133
2918280533	73	92.06	11	72	6	63	4.0e-21	69	COG5457	Uncharacterized conserved protein YjiS, DUF1127 family	63
2918280534	319	98.67	6	298	2	298	5.8e-72	237.4	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918280537	320	97.78	7	317	5	312	1.4e-116	383.3	COG0540	Aspartate carbamoyltransferase, catalytic chain	316
2918280538	435	96.75	8	435	6	422	0.0e+00	445.6	COG0044	Dihydroorotase or related cyclic amidohydrolase	430
2918280539	198	97.07	1	191	6	204	3.2e-62	204.5	COG0344	Phospholipid biosynthesis protein PlsY, probable glycerol-3-phosphate acyltransferase	200
2918280540	373	99.16	8	373	2	357	3.5e-111	366.1	COG0758	Predicted Rossmann fold nucleotide-binding protein DprA/Smf involved in DNA uptake	350
2918280541	929	97.57	4	588	2	562	0.0e+00	681.8	COG0550	DNA topoisomerase IA	570
2918280541	929	98.12	581	921	7	320	1.2e-85	281.6	COG1754	Uncharacterized C-terminal domain of topoisomerase IA	298
2918280543	749	99.16	9	718	5	709	0.0e+00	637.4	COG0557	Exoribonuclease R	706
2918280544	503	76.23	83	442	59	369	2.7e-79	261.2	COG0793	C-terminal processing protease CtpA/Prc, contains a PDZ domain	406
2918280545	55	92.16	3	53	5	51	2.5e-21	70.3	COG0267	Ribosomal protein L33	50
2918280546	462	98.85	4	457	1	430	0.0e+00	466.2	COG3706	Two-component response regulator, PleD family, consists of two REC domains and a diguanylate cyclase (GGDEF) domain	435
2918280547	129	92.48	7	129	5	127	1.3e-36	119.8	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918280548	247	92.35	47	232	6	174	4.4e-45	148	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2918280550	326	98.78	8	326	3	325	1.6e-102	337.2	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
2918280553	1149	49.19	81	169	20	80	5.9e-07	5.7	COG2351	5-hydroxyisourate hydrolase (purine catabolism), transthyretin-related family	124
2918280553	1149	49.19	289	372	20	80	5.9e-07	5.1	COG2351	5-hydroxyisourate hydrolase (purine catabolism), transthyretin-related family	124
2918280553	1149	49.19	492	575	20	80	5.9e-07	8.4	COG2351	5-hydroxyisourate hydrolase (purine catabolism), transthyretin-related family	124
2918280554	606	99.49	4	595	1	583	0.0e+00	754.5	COG0173	Aspartyl-tRNA synthetase	585
2918280555	388	99.45	4	366	1	360	5.7e-122	401.8	COG0349	Ribonuclease D	361
2918280556	429	36.19	240	424	87	179	3.9e-05	15.7	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
2918280557	505	91.72	14	489	2	455	5.1e-96	316.7	COG0248	Exopolyphosphatase/pppGpp-phosphohydrolase	492
2918280558	715	98.43	9	700	6	693	0.0e+00	935.1	COG0855	Polyphosphate kinase	696
2918280559	172	98.77	1	170	1	161	1.4e-40	133.2	COG2062	Phosphohistidine phosphatase SixA	163
2918280560	521	88.84	13	512	24	421	4.8e-66	217.7	COG3025	Inorganic triphosphatase YgiF, contains CYTH and CHAD domains	432
2918280561	638	99.04	5	634	2	622	0.0e+00	860.6	COG1154	Deoxyxylulose-5-phosphate synthase	627
2918280562	296	78.05	3	296	4	259	1.8e-78	258	COG0142	Geranylgeranyl pyrophosphate synthase	322
2918280563	84	79.01	1	81	7	70	4.3e-23	75.5	COG1722	Exonuclease VII small subunit	81
2918280564	309	89.63	1	308	4	314	5.4e-103	339	COG0123	Acetoin utilization deacetylase AcuC or a related deacetylase	340
2918280565	75	91.25	1	75	6	78	4.5e-25	82	COG0425	TusA-related sulfurtransferase	78
2918280566	118	67.8	6	105	13	92	1.7e-17	58.5	COG0640	DNA-binding transcriptional regulator, ArsR family	110
2918280567	134	95.16	4	129	3	120	7.6e-30	98.2	COG2363	Uncharacterized membrane protein YgdD, TMEM256/DUF423 family	124
2918280568	173	93.98	30	164	7	131	7.3e-37	120.5	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918280569	183	95.6	1	183	8	181	8.9e-68	222.3	COG3803	Uncharacterized conserved protein, DUF924 family	182
2918280570	254	96.39	3	254	11	277	4.5e-75	247.2	COG2857	Cytochrome c1	250
2918280571	422	98.77	8	398	5	404	0.0e+00	497.5	COG1290	Cytochrome b subunit of the bc complex	381
2918280572	189	90	13	189	7	168	3.1e-53	174.7	COG0723	Rieske Fe-S protein	177
2918280573	150	96.1	1	149	2	149	1.3e-49	162.4	COG0219	tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain	155
2918280574	294	91.09	9	294	4	279	3.2e-122	401.6	COG0408	Coproporphyrinogen III oxidase	303
2918280575	416	97.59	9	412	4	408	9.1e-90	296.1	COG0617	tRNA nucleotidyltransferase/poly(A) polymerase	412
2918280577	216	77.33	31	206	13	145	3.1e-19	63.6	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2918280578	195	62.62	25	190	46	174	5.2e-55	180.4	COG3816	Uncharacterized protein	205
2918280579	343	96.06	19	340	3	319	5.8e-96	315.8	COG0714	MoxR-like ATPase	329
2918280580	299	59.47	10	294	164	411	9.8e-46	150.9	COG1721	Uncharacterized conserved protein, DUF58 family, contains vWF domain	416
2918280584	4234	65.28	4	446	226	648	0.0e+00	237.6	COG1020	Non-ribosomal peptide synthetase component F	642
2918280584	4234	67.1	3865	4190	2	258	3.0e-48	159.1	COG3320	Thioester reductase domain of alpha aminoadipate reductase Lys2 and NRPSs	382
2918280584	4234	74.32	3737	3803	7	61	4.7e-08	14	COG3433	Aryl carrier domain	74
2918280584	4234	79.73	544	617	4	62	4.7e-08	4.6	COG3433	Aryl carrier domain	74
2918280584	4234	98.77	860	1508	8	647	0.0e+00	319.3	COG1020	Non-ribosomal peptide synthetase component F	642
2918280584	4234	99.69	1919	2574	3	648	0.0e+00	335	COG1020	Non-ribosomal peptide synthetase component F	642
2918280584	4234	99.85	2974	3640	2	648	0.0e+00	365.7	COG1020	Non-ribosomal peptide synthetase component F	642
2918280586	136	87.96	3	102	12	106	4.3e-05	12.6	COG5569	Periplasmic Cu and Ag efflux protein CusF	108
2918280588	566	49.87	315	560	4	194	7.6e-35	17.8	COG0477	MFS family permease	338
2918280588	566	75.2	65	349	3	290	7.6e-35	98.9	COG0477	MFS family permease	338
2918280589	373	96.02	1	359	8	345	2.4e-120	395.7	COG1566	Multidrug resistance efflux pump	352
2918280590	209	88.52	4	207	13	197	1.0e-23	79.3	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918280591	390	95.81	18	385	10	375	1.7e-113	373.5	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
2918280592	430	97.49	1	429	7	433	0.0e+00	444.3	COG1253	Hemolysin or related protein, contains CBS domains	429
2918280593	201	93.78	2	200	9	204	1.8e-46	152.4	COG3932	Uncharacterized conserved protein	209
2918280594	393	76.14	21	393	90	389	2.3e-72	239.1	COG0642	Signal transduction histidine kinase	336
2918280595	366	92.51	140	365	13	222	1.3e-41	136.4	COG5012	Methanogenic corrinoid protein MtbC1	227
2918280596	144	90.98	16	144	8	128	4.2e-28	92.3	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918280597	712	50.4	595	701	22	84	2.0e-07	26	COG2198	HPt (histidine-containing phosphotransfer) domain	122
2918280597	712	60.44	443	584	13	122	5.4e-05	16.5	COG4567	Two-component response regulator, ActR/RegA family, consists of REC and Fis-type HTH domains	182
2918280597	712	72.59	41	421	107	392	8.8e-85	280.1	COG0642	Signal transduction histidine kinase	336
2918280598	199	27.84	47	197	39	92	8.0e-07	22.8	COG1896	5'-deoxynucleotidase YfbR and related HD superfamily hydrolases	193
2918280599	171	64.62	18	136	2	85	4.0e-19	63.5	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918280600	554	98.18	1	553	10	547	0.0e+00	507.6	COG1766	Flagellar biosynthesis/type III secretory pathway M-ring protein FliF/YscJ	545
2918280601	252	74.49	9	251	40	220	6.2e-22	72.6	COG1317	Flagellar biosynthesis/type III secretory pathway protein FliH	234
2918280602	109	53.19	7	103	67	141	1.0e-30	101.7	COG1886	Flagellar motor switch/type III secretory pathway protein FliN	136
2918280603	304	94.38	40	300	2	253	3.0e-53	174.8	COG1291	Flagellar motor component MotA	266
2918280604	508	97.22	1	498	7	460	0.0e+00	469.4	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2918280605	723	98.42	20	723	9	694	0.0e+00	858.8	COG1298	Flagellar biosynthesis pathway, component FlhA	696
2918280606	354	17.15	1	103	1	71	2.1e-48	29.4	COG1419	Flagellar biosynthesis GTPase FlhF	407
2918280606	354	47.34	105	338	210	405	2.1e-48	129.1	COG1419	Flagellar biosynthesis GTPase FlhF	407
2918280607	264	90.23	18	264	3	242	2.0e-50	166.2	COG0455	MinD-like ATPase involved in chromosome partitioning or flagellar assembly	262
2918280612	145	54.8	2	141	47	143	1.5e-03	13.3	COG1592	Rubrerythrin	166
2918280613	449	96.83	3	441	13	440	0.0e+00	563.1	COG1157	Flagellar biosynthesis/type III secretory pathway ATPase	441
2918280614	243	99.57	1	225	1	231	4.4e-76	249.7	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918280615	40	57.14	2	39	27	62	1.3e-13	45	COG5457	Uncharacterized conserved protein YjiS, DUF1127 family	63
2918280616	302	98.34	5	297	2	297	1.9e-67	222.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918280617	280	95.19	3	268	2	258	1.5e-83	274.5	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
2918280618	393	98.3	25	393	2	347	1.1e-100	331.7	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
2918280619	121	89.47	1	119	5	123	1.9e-33	109.6	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918280620	167	88.48	9	167	13	158	3.8e-32	105.6	COG0835	Chemotaxis signal transduction protein	165
2918280621	923	11.54	655	778	616	702	0.0e+00	27.8	COG0643	Chemotaxis protein histidine kinase CheA	716
2918280621	923	17.64	1	199	6	138	0.0e+00	80.8	COG0643	Chemotaxis protein histidine kinase CheA	716
2918280621	923	53.45	179	642	341	743	0.0e+00	522	COG0643	Chemotaxis protein histidine kinase CheA	716
2918280621	923	65.38	790	923	6	124	7.7e-07	22.9	COG4567	Two-component response regulator, ActR/RegA family, consists of REC and Fis-type HTH domains	182
2918280623	214	85.98	4	213	17	200	1.3e-33	110.5	COG5385	Uncharacterized protein	214
2918280625	126	83.09	1	126	20	132	6.2e-33	108.2	COG3474	Cytochrome c2	135
2918280627	341	97.58	6	338	5	327	7.6e-117	384.9	COG1995	4-hydroxy-L-threonine phosphate dehydrogenase PdxA	332
2918280628	489	79.38	21	297	13	270	7.4e-35	115.5	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
2918280629	364	99.18	5	364	3	364	1.6e-61	202.9	COG0795	Lipopolysaccharide export LptBFGC system, permease protein LptF	364
2918280630	504	97.33	5	502	12	485	0.0e+00	571.4	COG0260	Leucyl aminopeptidase	485
2918280631	149	100	1	147	1	144	5.5e-40	131.2	COG2927	DNA polymerase III, chi subunit	144
2918280632	525	95.61	173	525	4	221	1.6e-47	155.8	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
2918280633	778	73.6	248	647	101	390	1.5e-69	228.7	COG0642	Signal transduction histidine kinase	336
2918280633	778	92.48	652	778	6	128	4.0e-20	64.5	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918280634	404	71.57	13	403	107	388	6.6e-71	234.2	COG0642	Signal transduction histidine kinase	336
2918280635	516	98.48	3	197	3	197	6.4e-69	225.9	COG0518	GMP synthase - Glutamine amidotransferase domain	198
2918280635	516	100	198	516	1	316	0.0e+00	503.9	COG0519	GMP synthase, PP-ATPase domain/subunit	315
2918280636	185	58.58	4	152	28	126	8.2e-09	29.4	COG1247	L-amino acid N-acyltransferase YncA	169
2918280637	455	89.39	99	434	38	357	2.8e-94	310.8	COG0144	16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family	355
2918280638	387	31.13	50	170	18	135	1.3e-92	26.9	COG2821	Membrane-bound lytic murein transglycosylase	373
2918280638	387	65.17	138	384	129	375	1.3e-92	284.2	COG2821	Membrane-bound lytic murein transglycosylase	373
2918280639	179	74.69	6	171	36	156	1.8e-09	32.6	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2918280640	181	82.3	1	181	28	199	2.4e-19	65.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918280641	362	95.13	1	356	9	379	2.0e-53	176.3	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918280642	1042	99.9	8	1021	1	1013	0.0e+00	948.9	COG0841	Multidrug efflux pump subunit AcrB	1009
2918280643	110	93.04	3	108	2	108	4.3e-16	52.1	COG5447	Uncharacterized protein	115
2918280644	472	63.85	6	189	78	243	1.8e-15	51.9	COG5010	Flp pilus assembly protein TadD, contains TPR repeats	257
2918280645	301	98.92	11	295	3	278	1.7e-89	294.2	COG0287	Prephenate dehydrogenase	279
2918280646	363	98.61	8	363	3	358	3.7e-106	349.5	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
2918280647	298	84.16	2	100	8	92	6.4e-16	52.4	COG1605	Chorismate mutase	101
2918280648	399	94.09	8	386	21	370	0.0e+00	488.7	COG2021	Homoserine acetyltransferase	368
2918280649	221	44.8	4	217	54	178	1.6e-08	29.7	COG0500	SAM-dependent methyltransferase	257
2918280650	174	51.14	81	152	7	51	4.1e-03	11.3	COG1873	Sporulation protein YlmC, PRC-barrel domain family	87
2918280651	249	99.25	2	246	2	267	3.1e-63	208.2	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918280652	189	97.24	2	184	3	178	2.7e-60	197.6	COG3545	Predicted esterase of the alpha/beta hydrolase fold	181
2918280653	403	67.76	88	392	134	421	1.3e-43	144.1	COG0840	Methyl-accepting chemotaxis protein	408
2918280654	259	27.96	9	243	110	187	1.0e-06	23.8	COG0500	SAM-dependent methyltransferase	257
2918280655	253	91.92	1	226	20	258	5.4e-55	181.2	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2918280656	201	95.81	1	201	1	206	2.8e-35	116.6	COG0625	Glutathione S-transferase	211
2918280657	140	84.15	2	139	7	144	1.2e-47	156.2	COG3542	Predicted sugar epimerase, cupin superfamily	162
2918280658	138	96.97	1	121	1	128	5.3e-34	111.7	COG0789	DNA-binding transcriptional regulator, MerR family	124
2918280659	814	9.3	14	85	4	71	0.0e+00	37.8	COG2217	Cation transport ATPase	713
2918280659	814	99.59	81	808	2	729	0.0e+00	910.4	COG2217	Cation transport ATPase	713
2918280660	359	98.61	11	356	4	287	3.3e-89	293.3	COG0191	Fructose/tagatose bisphosphate aldolase	286
2918280661	981	73.6	506	828	102	391	2.6e-62	206.3	COG0642	Signal transduction histidine kinase	336
2918280661	981	91.73	840	967	9	130	8.3e-18	57.5	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918280662	66	93.15	1	66	4	71	8.4e-17	56	COG2608	Copper chaperone CopZ	71
2918280664	99	94.81	1	92	1	73	3.8e-33	107.9	COG0227	Ribosomal protein L28	77
2918280666	331	98.14	6	326	4	320	5.5e-114	375	COG1703	Putative periplasmic protein kinase ArgK or related GTPase of G3E family	323
2918280667	184	93.88	2	181	12	195	2.7e-22	69.9	COG3230	Heme oxygenase	196
2918280668	618	100	105	600	1	497	0.0e+00	792.7	COG5265	ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components	497
2918280669	806	12.24	378	456	99	150	4.4e-111	6.8	COG0840	Methyl-accepting chemotaxis protein	408
2918280669	806	24.24	227	383	41	143	4.4e-111	37.3	COG0840	Methyl-accepting chemotaxis protein	408
2918280669	806	78.12	437	745	94	425	4.4e-111	336.4	COG0840	Methyl-accepting chemotaxis protein	408
2918280672	107	91.59	1	105	7	104	9.1e-22	71.9	COG4392	Branched-chain amino acid transport protein	107
2918280673	241	94.14	1	240	11	235	8.8e-61	199.9	COG1296	Predicted branched-chain amino acid permease (azaleucine resistance)	238
2918280674	218	91.45	2	218	18	231	8.4e-51	166.8	COG1272	Predicted membrane channel-forming protein YqfA, hemolysin III family	226
2918280675	246	88.64	4	243	10	165	9.8e-28	91.5	COG0681	Signal peptidase I	166
2918280676	170	94.01	2	165	5	161	4.4e-28	92.7	COG3685	Ferritin-like metal-binding protein YciE	167
2918280677	876	99.38	5	858	1	800	0.0e+00	1170.7	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
2918280678	174	79.65	27	172	12	148	4.2e-20	66.7	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2918280679	258	97.41	1	258	2	264	3.2e-22	70.2	COG3217	Uncharacterized conserved protein YcbX, contains MOSC and Fe-S domains	270
2918280681	283	98.26	2	283	1	282	2.2e-75	247.9	COG2890	Methylase of polypeptide chain release factors	280
2918280682	142	82.17	10	127	15	120	7.8e-41	132.9	COG2852	Very-short-patch-repair endonuclease	129
2918280683	357	98.07	1	357	5	360	0.0e+00	522.6	COG0216	Protein chain release factor A	363
2918280684	435	95.89	4	409	2	398	5.4e-90	296.4	COG0373	Glutamyl-tRNA reductase	414
2918280685	376	98.65	9	369	2	366	0.0e+00	482	COG0821	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase IspG/GcpE	361
2918280686	440	26.46	24	151	4	80	3.8e-30	86.5	COG1426	Cytoskeletal protein RodZ, contains Xre-like HTH and DUF4115 domains	284
2918280686	440	40.55	249	390	161	278	3.8e-30	15.3	COG1426	Cytoskeletal protein RodZ, contains Xre-like HTH and DUF4115 domains	284
2918280687	769	98.41	23	769	5	748	0.0e+00	890.3	COG3605	Signal transduction protein containing GAF and PtsI domains	756
2918280688	359	95.07	22	345	11	338	2.1e-62	205.7	COG2070	NAD(P)H-dependent flavin oxidoreductase YrpB, nitropropane dioxygenase family	336
2918280689	411	99.77	1	409	1	442	0.0e+00	478.8	COG0527	Aspartokinase	447
2918280690	250	95.49	1	250	10	242	2.7e-91	299.6	COG2227	2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase	243
2918280691	152	96.71	1	149	4	150	8.4e-41	133.7	COG1762	Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type)	152
2918280692	196	94.55	1	110	1	104	2.0e-25	82.5	COG1544	Ribosome-associated translation inhibitor RaiA	110
2918280693	506	96.65	1	502	15	447	0.0e+00	513.4	COG1508	DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog	444
2918280694	269	98.35	30	269	5	243	1.2e-114	375.9	COG1137	ABC-type lipopolysaccharide export system, ATPase component	243
2918280695	285	68.21	9	142	6	123	1.2e-25	33.8	COG1934	Lipopolysaccharide export system protein LptA	173
2918280695	285	84.39	127	280	25	170	1.2e-25	52	COG1934	Lipopolysaccharide export system protein LptA	173
2918280696	232	87.04	20	225	25	212	6.8e-30	98.5	COG5375	Uncharacterized protein	216
2918280697	338	98.02	26	224	4	201	9.8e-75	244.5	COG0794	D-arabinose 5-phosphate isomerase GutQ	202
2918280698	208	53.31	5	208	12	204	3.9e-71	234.6	COG0349	Ribonuclease D	361
2918280700	332	96.74	8	293	3	269	7.2e-57	187.1	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
2918280701	266	97.8	1	266	5	271	6.0e-95	312.2	COG1968	Undecaprenyl pyrophosphate phosphatase UppP	270
2918280702	482	99.13	24	475	2	455	0.0e+00	493.6	COG0493	NADPH-dependent glutamate synthase beta chain or related oxidoreductase	457
2918280703	1515	92.43	1214	1505	4	284	6.9e-99	325.1	COG0070	Glutamate synthase domain 3	301
2918280703	1515	98.77	724	1209	5	487	0.0e+00	654.6	COG0069	Glutamate synthase domain 2	485
2918280703	1515	99.19	25	407	3	371	1.7e-128	422.8	COG0067	Glutamate synthase domain 1	371
2918280704	150	79.63	6	143	27	155	6.5e-13	43.6	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2918280705	222	94.42	2	211	2	204	9.6e-40	131	COG0625	Glutathione S-transferase	211
2918280706	277	63.86	4	267	119	353	2.0e-15	52	COG0457	Tetratricopeptide (TPR) repeat	291
2918280707	292	19.63	1	95	3	65	1.6e-21	13.2	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2918280707	292	59.19	100	291	115	304	1.6e-21	57.3	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2918280708	146	90.28	6	145	4	133	2.0e-27	90.2	COG2703	Hemerythrin	144
2918280710	376	100	1	376	1	365	1.8e-113	373.9	COG0592	DNA polymerase III sliding clamp (beta) subunit, PCNA homolog	364
2918280711	393	99.45	16	392	2	362	1.8e-94	311.2	COG1195	Recombinational DNA repair ATPase RecF	363
2918280712	822	99.69	6	822	3	641	0.0e+00	955.4	COG0187	DNA gyrase/topoisomerase IV, subunit B	635
2918280713	89	44.62	7	86	2	59	7.0e-17	56.9	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918280715	456	23.67	23	99	15	85	8.2e-12	8.6	COG4974	Site-specific recombinase XerD	300
2918280715	456	85.33	121	416	8	263	8.2e-12	25.9	COG4974	Site-specific recombinase XerD	300
2918280716	187	88.05	1	186	9	207	5.2e-40	131.9	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
2918280719	38	8.36	4	38	296	322	6.9e-05	16.8	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918280720	402	98.42	22	402	7	379	5.3e-78	256.8	COG1454	Alcohol dehydrogenase, class IV	377
2918280721	676	29.46	496	669	336	500	2.3e-31	71.1	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918280721	676	59.82	2	572	126	460	2.3e-31	47.4	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918280722	1831	15.32	1577	1774	74	128	6.9e-13	5.3	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
2918280722	1831	18.08	498	564	125	171	5.9e-04	9.7	COG5010	Flp pilus assembly protein TadD, contains TPR repeats	257
2918280722	1831	24.79	260	482	20	108	6.9e-13	36.3	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
2918280722	1831	45	580	752	108	224	5.9e-04	14.8	COG5010	Flp pilus assembly protein TadD, contains TPR repeats	257
2918280722	1831	58.92	1168	1550	158	398	2.9e-16	53.5	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918280724	422	17.39	162	421	156	219	6.8e-04	14.4	COG0457	Tetratricopeptide (TPR) repeat	291
2918280726	379	88.04	1	378	6	395	1.1e-57	185.2	COG3182	Uncharacterized iron-regulated membrane protein	442
2918280727	703	97.61	1	703	20	795	1.4e-121	402.2	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2918280728	147	85.71	11	137	13	126	1.5e-25	84.2	COG2346	Truncated hemoglobin YjbI	133
2918280732	441	99.02	6	421	2	406	1.0e-36	121.4	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918280734	434	92.42	6	416	3	380	3.2e-28	93.5	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918280735	273	60.22	8	270	54	221	2.2e-14	48.6	COG0500	SAM-dependent methyltransferase	257
2918280736	795	72.84	484	740	2	229	4.9e-31	102.1	COG1216	Glycosyltransferase, GT2 family	305
2918280737	256	7.14	47	88	414	453	5.8e-34	26.4	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918280737	256	9.29	84	136	398	449	5.8e-34	33.2	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918280737	256	10	1	59	398	453	5.8e-34	32.7	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918280737	256	23.57	121	251	398	529	5.8e-34	57.4	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918280738	455	97.95	24	446	8	389	7.8e-34	111.8	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918280739	570	95	2	566	14	564	0.0e+00	684.7	COG4618	ABC-type protease/lipase transport system, ATPase and permease components	580
2918280740	338	99.7	5	329	1	328	0.0e+00	437.1	COG1087	UDP-glucose 4-epimerase	329
2918280741	167	78.95	21	154	6	110	2.8e-15	50.8	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918280742	391	84.89	6	362	11	319	1.5e-39	130.6	COG5330	Uncharacterized conserved protein, DUF2336 family	364
2918280744	287	92.39	10	287	14	280	4.6e-87	286.4	COG5473	Uncharacterized membrane protein	290
2918280745	206	98.42	7	198	3	189	3.3e-89	292.2	COG3005	Tetraheme cytochrome c subunit of nitrate or TMAO reductase	190
2918280746	156	89.68	1	150	15	153	3.8e-53	174.1	COG3043	Nitrate reductase cytochrome c-type subunit	155
2918280747	831	99.75	2	831	2	809	0.0e+00	738.4	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
2918280748	96	87.23	1	88	6	87	1.4e-16	54.6	COG3062	Cytoplasmic chaperone NapD for the signal peptide of periplasmic nitrate reductase NapAB	94
2918280749	56	75.81	1	56	7	53	4.8e-18	59.5	COG4459	Periplasmic nitrate reductase system, NapE component	62
2918280750	202	35.78	8	86	3	80	4.2e-18	26.6	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2918280750	202	47.25	81	188	104	206	4.2e-18	34.1	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2918280751	322	82.32	1	318	63	388	5.2e-44	145.6	COG3213	Uncharacterized protein involved in response to NO	396
2918280752	304	78.86	5	298	2	277	2.1e-40	133.2	COG0826	Collagenase-like protease, PrtC family	347
2918280753	328	80.57	1	326	3	284	1.2e-99	328.1	COG0826	Collagenase-like protease, PrtC family	347
2918280754	211	67.26	24	185	37	149	1.1e-24	81.3	COG3154	Predicted lipid carrier protein YhbT, SCP2 domain	168
2918280756	603	96.63	1	591	16	618	7.8e-129	425.7	COG3387	Glucoamylase (glucan-1,4-alpha-glucosidase), GH15 family	612
2918280757	666	50.36	247	648	131	412	1.1e-13	45.6	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918280758	311	98.01	2	300	1	295	5.4e-65	214.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918280759	187	95.83	1	187	2	185	1.1e-71	234.8	COG0450	Alkyl hydroperoxide reductase subunit AhpC (peroxiredoxin)	194
2918280760	526	99.23	1	521	1	517	0.0e+00	940.4	COG3634	Alkyl hydroperoxide reductase subunit AhpF	520
2918280762	863	97.61	1	863	6	741	0.0e+00	557	COG0643	Chemotaxis protein histidine kinase CheA	716
2918280763	137	86.47	11	134	5	119	9.1e-27	87.9	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918280764	287	99.26	16	287	1	268	5.6e-83	272.7	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
2918280766	354	98.01	1	354	1	345	1.6e-104	344.2	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
2918280767	513	92.73	170	336	9	161	2.4e-107	108.2	COG0835	Chemotaxis signal transduction protein	165
2918280767	513	93.33	2	167	9	162	2.4e-107	110.1	COG0835	Chemotaxis signal transduction protein	165
2918280767	513	93.33	343	507	6	159	2.4e-107	137.2	COG0835	Chemotaxis signal transduction protein	165
2918280768	642	64.71	38	346	146	420	6.7e-91	159.2	COG0840	Methyl-accepting chemotaxis protein	408
2918280768	642	66.12	338	642	133	413	6.7e-91	146.4	COG0840	Methyl-accepting chemotaxis protein	408
2918280769	134	89.58	4	134	3	131	9.9e-28	91.4	COG2703	Hemerythrin	144
2918280770	641	78.68	104	487	83	392	4.7e-55	182.2	COG0642	Signal transduction histidine kinase	336
2918280770	641	86.47	515	640	5	119	1.5e-19	64.3	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918280771	208	66.83	1	199	7	141	1.1e-25	85	COG1776	Chemotaxis protein CheY-P-specific phosphatase CheC	203
2918280772	120	87.22	2	119	6	121	1.0e-22	74.8	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918280773	342	71.92	3	141	32	136	4.7e-17	55.6	COG2172	Anti-sigma regulatory factor (Ser/Thr protein kinase)	146
2918280774	135	89.04	4	135	14	143	3.7e-25	82.6	COG2172	Anti-sigma regulatory factor (Ser/Thr protein kinase)	146
2918280775	121	81.2	1	111	5	99	9.3e-19	61.8	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
2918280776	277	88.03	152	263	3	105	2.1e-27	88.1	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
2918280777	128	93.23	1	127	5	128	1.1e-17	58.5	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918280778	526	71.07	129	502	111	390	1.3e-49	164.5	COG0642	Signal transduction histidine kinase	336
2918280780	122	93.23	1	122	5	128	9.3e-33	107.5	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918280781	411	61.41	72	387	160	420	1.6e-36	120.2	COG0840	Methyl-accepting chemotaxis protein	408
2918280782	207	88.61	1	182	22	200	2.0e-56	185.1	COG4566	Two-component response regulator, FixJ family, consists of REC and HTH domains	202
2918280783	621	79.19	227	611	78	389	1.6e-60	199.8	COG0642	Signal transduction histidine kinase	336
2918280784	213	97.03	13	213	4	199	1.4e-78	257.5	COG4566	Two-component response regulator, FixJ family, consists of REC and HTH domains	202
2918280785	247	90.73	35	232	9	194	6.3e-67	219.3	COG0437	Fe-S-cluster-containing dehydrogenase component	203
2918280786	377	83.61	6	313	9	263	5.9e-22	72.3	COG3301	Formate-dependent nitrite reductase, membrane component NrfD	305
2918280787	1035	98.77	2	1032	2	801	1.2e-126	418.5	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
2918280788	329	90.37	10	317	28	299	5.5e-109	358.4	COG3258	Cytochrome c	293
2918280791	525	90.7	1	511	5	511	9.1e-73	240	COG0143	Methionyl-tRNA synthetase	558
2918280792	146	76.74	25	142	16	114	2.9e-17	56.9	COG0662	Mannose-6-phosphate isomerase, cupin superfamily	127
2918280793	456	95.18	18	455	6	420	7.4e-104	342.1	COG3486	Lysine/ornithine N-monooxygenase	436
2918280794	365	80.72	1	353	85	444	1.2e-94	312	COG0160	4-aminobutyrate aminotransferase or related aminotransferase	447
2918280795	415	83.05	2	381	3	340	1.5e-43	143.7	COG0644	Dehydrogenase (flavoprotein)	396
2918280797	155	79.01	2	146	27	154	1.0e-10	36.6	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2918280798	422	91.86	108	396	7	277	5.0e-24	80.2	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918280799	561	62.81	5	456	236	642	5.8e-70	231.1	COG1020	Non-ribosomal peptide synthetase component F	642
2918280800	87	27.16	1	57	28	49	2.9e-04	15.3	COG0236	Acyl carrier protein	80
2918280801	308	87.74	10	308	31	309	8.8e-32	105.4	COG0657	Acetyl esterase/lipase	312
2918280802	138	97.37	17	125	3	113	7.7e-21	68.7	COG0607	Rhodanese-related sulfurtransferase	110
2918280803	1444	89.49	1180	1425	5	234	2.7e-21	68.6	COG3319	Thioesterase domain of type I polyketide synthase or non-ribosomal peptide synthetase	257
2918280803	1444	99.07	339	990	7	648	0.0e+00	438.5	COG1020	Non-ribosomal peptide synthetase component F	642
2918280804	315	87.71	2	280	33	296	1.7e-10	34.9	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918280805	393	96.91	6	385	4	379	1.4e-62	206.6	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918280807	298	64.67	1	298	158	459	5.4e-78	257.3	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2918280810	271	98.87	9	268	4	265	6.4e-52	171	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918280811	360	89.52	1	357	5	320	1.4e-113	374.2	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
2918280812	593	96.88	21	579	7	533	3.0e-120	396.5	COG1178	ABC-type Fe3+ transport system, permease component	540
2918280813	353	85.71	68	353	3	260	5.2e-35	115.7	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
2918280814	256	99.25	9	253	2	267	1.1e-69	229.4	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918280815	149	91.19	1	147	13	157	5.8e-40	130.6	COG2030	Acyl dehydratase	159
2918280816	142	75.18	11	129	17	122	3.1e-19	63.2	COG1545	Uncharacterized OB-fold protein, contains Zn-ribbon domain	140
2918280817	388	97.97	6	388	5	390	5.6e-57	187.9	COG0183	Acetyl-CoA acetyltransferase	392
2918280818	400	98.5	1	400	5	399	0.0e+00	474.1	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2918280819	336	97.67	42	333	3	296	4.5e-44	145.7	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918280820	501	93.66	6	498	27	558	9.4e-125	411.3	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2918280821	176	90.65	16	145	11	136	7.8e-24	78.5	COG0824	Acyl-CoA thioesterase FadM	137
2918280822	751	97.48	42	751	21	795	6.1e-74	244.5	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2918280824	541	93.23	12	431	6	418	1.3e-40	134.3	COG3182	Uncharacterized iron-regulated membrane protein	442
2918280825	98	6.83	2	85	171	224	2.1e-03	11	COG1287	Asparagine N-glycosylation enzyme, membrane subunit Stt3	773
2918280826	386	93.08	1	371	15	377	2.5e-58	192.5	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918280827	662	97.79	20	244	2	222	1.0e-86	284	COG1136	ABC-type lipoprotein export system, ATPase component	226
2918280827	662	99.8	284	662	2	510	3.6e-76	251.8	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
2918280828	488	98.48	18	484	2	454	2.9e-105	347.1	COG1538	Outer membrane protein TolC	457
2918280829	393	16.48	240	329	49	121	3.2e-46	15.8	COG3182	Uncharacterized iron-regulated membrane protein	442
2918280829	393	17.83	305	392	317	395	3.2e-46	30.8	COG3182	Uncharacterized iron-regulated membrane protein	442
2918280829	393	46.73	8	242	7	213	3.2e-46	121.4	COG3182	Uncharacterized iron-regulated membrane protein	442
2918280830	595	16.29	479	585	292	356	5.8e-95	1.5	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918280830	595	96.99	18	456	9	395	5.8e-95	313.3	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918280831	768	19.15	314	421	180	242	6.1e-87	18.6	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
2918280831	768	72.45	452	720	16	207	1.0e-32	106.1	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918280831	768	87.23	3	335	2	288	6.1e-87	266	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
2918280832	377	99.49	1	377	1	392	1.4e-114	377.7	COG0183	Acetyl-CoA acetyltransferase	392
2918280833	515	97.54	1	515	6	559	6.1e-124	408.9	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2918280834	232	93.78	12	208	6	201	2.5e-26	88	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918280835	328	75.99	11	321	3	252	4.8e-62	204.5	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
2918280836	310	98.99	3	305	3	297	7.5e-106	348.2	COG3246	Uncharacterized conserved protein, DUF849 family	298
2918280837	405	98.09	15	384	5	363	3.1e-44	145.8	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918280838	510	94.23	1	510	11	516	0.0e+00	571.9	COG0578	Glycerol-3-phosphate dehydrogenase	532
2918280839	367	98.57	1	354	4	348	2.7e-92	304.2	COG3839	ABC-type sugar transport system, ATPase component	338
2918280840	361	99.14	1	353	1	347	2.3e-99	327.4	COG3839	ABC-type sugar transport system, ATPase component	338
2918280841	294	94.97	1	294	12	294	1.2e-64	213.1	COG1175	ABC-type sugar transport system, permease component	295
2918280842	265	94.35	2	265	16	282	1.9e-70	231.9	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
2918280843	93	94.85	1	93	6	97	9.5e-33	107.1	COG5477	Predicted small integral membrane protein	97
2918280844	584	98.42	1	515	7	442	2.3e-70	232.5	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
2918280845	496	98.2	1	496	6	497	0.0e+00	717.4	COG0554	Glycerol kinase	499
2918280846	256	99.25	5	255	2	267	6.6e-66	217.1	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918280847	579	36.68	180	406	142	276	1.0e-14	14.6	COG0457	Tetratricopeptide (TPR) repeat	291
2918280847	579	63.86	9	239	131	365	1.0e-14	40.7	COG0457	Tetratricopeptide (TPR) repeat	291
2918280850	995	24.87	20	212	93	239	5.6e-48	12.9	COG4625	Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain	577
2918280850	995	90.52	370	995	57	591	5.6e-48	158.1	COG4625	Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain	577
2918280851	401	96.25	1	386	12	370	1.4e-103	341	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
2918280852	238	94.4	2	226	10	228	3.4e-62	204.3	COG1802	DNA-binding transcriptional regulator, GntR family	230
2918280853	329	96.69	4	329	3	323	6.7e-91	299.3	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
2918280854	178	88.7	1	167	9	165	3.4e-33	108.9	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
2918280855	425	98.94	45	425	3	377	9.2e-116	381.5	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
2918280856	716	79.7	7	388	64	432	6.7e-15	48.8	COG2723	Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase	460
2918280856	716	84.04	446	706	2	238	1.6e-61	201.9	COG1091	dTDP-4-dehydrorhamnose reductase	281
2918280857	314	93.29	9	308	14	305	2.8e-56	185.4	COG2017	Galactose mutarotase or related enzyme	308
2918280858	369	16.63	255	328	346	422	1.6e-08	8.7	COG2723	Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase	460
2918280858	369	39.31	27	216	72	253	1.6e-08	14.2	COG2723	Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase	460
2918280859	599	99.16	13	586	5	591	0.0e+00	484.1	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
2918280860	749	79.91	5	396	63	432	6.2e-19	61.6	COG2723	Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase	460
2918280860	749	90.43	460	732	4	258	3.5e-46	151.5	COG1091	dTDP-4-dehydrorhamnose reductase	281
2918280861	342	41.07	4	317	154	445	3.0e-13	43.3	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
2918280862	343	45.97	45	335	184	371	2.4e-07	25.4	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918280863	422	98.66	29	394	2	370	0.0e+00	490.4	COG0562	UDP-galactopyranose mutase	374
2918280865	348	84.99	1	333	23	356	2.2e-98	323.8	COG0153	Galactokinase	390
2918280866	356	97.36	46	356	2	333	4.2e-65	214.2	COG1085	Galactose-1-phosphate uridylyltransferase	338
2918280867	130	61.18	9	129	54	146	1.4e-12	42.3	COG0782	Transcription elongation factor, GreA/GreB family	151
2918280868	419	98.79	2	414	5	411	0.0e+00	497.9	COG0334	Glutamate dehydrogenase/leucine dehydrogenase	411
2918280869	554	85.28	49	548	56	391	6.1e-51	168.1	COG0642	Signal transduction histidine kinase	336
2918280870	213	97.52	13	213	3	199	1.0e-69	228.5	COG4566	Two-component response regulator, FixJ family, consists of REC and HTH domains	202
2918280871	239	99.19	1	238	1	246	3.6e-66	217.8	COG3279	DNA-binding response regulator, LytR/AlgR family	244
2918280872	564	98.74	5	563	3	552	0.0e+00	705.7	COG3275	Sensor histidine kinase, LytS/YehU family	557
2918280873	466	27.27	4	87	52	126	4.9e-129	21.9	COG1760	L-serine deaminase	262
2918280873	466	100	168	449	1	275	4.9e-129	400.3	COG1760	L-serine deaminase	262
2918280874	424	97.84	14	424	6	412	5.0e-114	375.6	COG0814	Amino acid permease	415
2918280876	801	70.3	289	657	113	389	2.2e-58	192.9	COG0642	Signal transduction histidine kinase	336
2918280876	801	90.98	672	800	9	129	6.5e-13	42.1	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918280878	503	81.21	60	488	79	454	6.6e-57	187.1	COG0076	Glutamate or tyrosine decarboxylase or a related PLP-dependent protein	460
2918280879	514	81.96	47	443	20	378	7.0e-22	71.9	COG1541	Phenylacetate-coenzyme A ligase PaaK, adenylate-forming domain family	438
2918280884	115	70.68	2	114	5	98	1.8e-22	74.1	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918280885	160	52.31	27	150	2	69	1.8e-16	55.4	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918280886	228	80.38	1	209	8	175	2.8e-26	87.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918280887	409	96.15	28	397	15	389	7.2e-68	223.9	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918280888	1024	99.8	2	1007	2	1013	0.0e+00	1048.6	COG0841	Multidrug efflux pump subunit AcrB	1009
2918280889	39	8.05	3	39	296	321	1.2e-04	16.1	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918280891	394	98.98	1	394	2	391	1.0e-116	384.7	COG0183	Acetyl-CoA acetyltransferase	392
2918280892	94	41.98	8	90	70	137	2.3e-13	44.7	COG3666	Transposase	161
2918280895	842	99.76	1	836	2	828	0.0e+00	504.5	COG3127	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component	829
2918280896	299	97.01	8	299	6	297	3.1e-65	215.3	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918280897	393	97.22	1	388	10	393	0.0e+00	431.7	COG2814	Predicted arabinose efflux permease, MFS family	394
2918280898	274	96.1	1	274	7	277	2.2e-94	310	COG0656	Aldo/keto reductase, related to diketogulonate reductase	280
2918280899	382	83.55	18	378	24	343	7.2e-03	10.3	COG0477	MFS family permease	338
2918280901	150	21.27	8	130	302	398	1.5e-11	38.2	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
2918280902	52	17.42	1	52	18	63	1.7e-03	12.2	COG3665	Uncharacterized conserved protein YcgI, DUF1989 family	264
2918280905	1176	70.05	727	1039	117	392	1.3e-57	190.9	COG0642	Signal transduction histidine kinase	336
2918280905	1176	90.98	1051	1176	8	128	7.5e-13	41.2	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918280906	2657	17.5	2531	2648	402	499	2.0e-26	40.9	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918280906	2657	21.07	459	649	267	384	2.0e-26	17.8	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918280906	2657	58.93	8	606	160	489	2.0e-26	14.9	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918280906	2657	61.07	935	1388	196	537	2.0e-26	10	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918280906	2657	75.71	2082	2551	33	456	2.0e-26	34.5	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918280908	338	61.62	22	338	3	307	1.1e-95	315.7	COG0248	Exopolyphosphatase/pppGpp-phosphohydrolase	492
2918280909	217	98.54	8	214	1	202	3.8e-78	256.4	COG0293	23S rRNA U2552 (ribose-2'-O)-methylase RlmE/FtsJ	205
2918280910	492	94.04	1	216	9	213	3.7e-116	171.6	COG0516	IMP dehydrogenase/GMP reductase	170
2918280910	492	94.5	262	481	12	217	3.7e-116	214.4	COG0516	IMP dehydrogenase/GMP reductase	170
2918280911	253	97.34	8	252	1	256	6.6e-31	101.8	COG0566	tRNA G18 (ribose-2'-O)-methylase SpoU	260
2918280912	82	94.05	1	81	1	79	5.2e-43	139.7	COG3813	Uncharacterized protein	84
2918280913	626	98.43	1	593	4	568	0.0e+00	648.1	COG3263	NhaP-type Na+/H+ and K+/H+ antiporter with C-terminal TrkAC and CorC domains	574
2918280915	154	96.32	12	154	5	135	2.5e-29	96.5	COG4520	Surface antigen	136
2918280917	597	98.65	16	588	8	591	0.0e+00	583.6	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
2918280918	245	71.2	61	245	55	232	3.1e-20	67.1	COG2365	Protein tyrosine/serine phosphatase	249
2918280921	279	100	1	278	1	279	3.8e-112	368.3	COG2961	23S rRNA A2030 N6-methylase RlmJ	279
2918280923	450	18.47	30	97	8	60	3.4e-73	6.7	COG4976	Predicted methyltransferase, contains TPR repeat	287
2918280923	450	20.21	98	170	13	70	3.4e-73	6.5	COG4976	Predicted methyltransferase, contains TPR repeat	287
2918280923	450	97.91	167	449	6	286	3.4e-73	236	COG4976	Predicted methyltransferase, contains TPR repeat	287
2918280925	69	25.29	1	69	10	74	2.6e-11	38.5	COG5662	Transmembrane transcriptional regulator (anti-sigma factor RsiW)	256
2918280926	286	98.88	38	284	2	266	3.2e-76	250.9	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918280927	157	87.63	1	157	16	178	1.5e-37	123.6	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918280928	490	11.75	27	97	90	126	1.4e-76	1.1	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
2918280928	490	96.83	166	484	9	313	1.4e-76	248.8	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
2918280929	398	92.06	23	177	11	184	4.0e-31	102.4	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
2918280930	832	99.2	9	821	6	751	0.0e+00	961.9	COG0058	Glucan phosphorylase	750
2918280931	337	98.81	8	337	3	334	1.3e-111	367.8	COG0136	Aspartate-semialdehyde dehydrogenase	334
2918280932	535	99.24	1	527	4	527	0.0e+00	773.8	COG4108	Peptide chain release factor RF-3	528
2918280933	526	38.91	90	515	368	602	1.1e-62	206.9	COG4191	Signal transduction histidine kinase regulating C4-dicarboxylate transport system	603
2918280934	134	48.28	9	133	2	113	3.7e-22	73.3	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918280935	318	92.6	11	316	9	321	1.6e-55	183.4	COG1305	Transglutaminase-like enzyme, putative cysteine protease	319
2918280936	870	97.13	36	520	9	482	0.0e+00	586.4	COG2308	Uncharacterized conserved protein, circularly permuted ATPgrasp superfamily	488
2918280936	870	99.04	545	867	1	310	2.6e-63	208.6	COG2307	Uncharacterized conserved protein, Alpha-E superfamily	313
2918280938	1114	88.76	3	314	16	315	1.3e-53	176.5	COG1305	Transglutaminase-like enzyme, putative cysteine protease	319
2918280938	1114	99.38	284	1114	2	804	0.0e+00	1145.2	COG4196	Uncharacterized conserved protein, DUF2126 family	808
2918280940	262	89.84	1	122	11	125	6.7e-14	46.2	COG3755	Uncharacterized conserved protein YecT, DUF1311 family	127
2918280941	157	98.06	2	156	3	154	9.4e-52	169.7	COG5528	Uncharacterized membrane protein	155
2918280942	419	82.61	1	255	1	228	7.2e-18	59.2	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
2918280943	316	92.33	13	315	23	311	8.5e-55	180.4	COG2017	Galactose mutarotase or related enzyme	308
2918280945	268	50.62	105	267	53	134	1.8e-05	18.9	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2918280946	176	95.54	23	173	4	153	3.3e-49	160.9	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
2918280948	79	23.21	1	68	7	58	6.3e-04	13.9	COG5461	Type IV pilus biogenesis protein CpaD/CtpE	224
2918280949	111	99.08	1	111	2	109	6.7e-27	88.7	COG3784	Uncharacterized conserved protein YdbL, DUF1318 family	109
2918280950	671	77.88	120	659	135	620	0.0e+00	467.9	COG3914	Predicted O-linked N-acetylglucosamine transferase, SPINDLY family	620
2918280951	241	53.16	32	93	23	64	1.8e-03	12.5	COG3074	Cell division protein ZapB, interacts with FtsZ	79
2918280952	186	85.25	1	180	6	161	7.8e-44	143.8	COG0241	Histidinol phosphatase or a related phosphatase	181
2918280953	766	94.22	9	761	26	775	1.9e-104	344.4	COG1452	LPS assembly outer membrane protein LptD (organic solvent tolerance protein OstA)	784
2918280954	80	49.37	1	80	71	148	4.4e-09	31.3	COG1522	DNA-binding transcriptional regulator, Lrp family	154
2918280955	514	89.81	1	490	30	496	0.0e+00	501.5	COG0513	Superfamily II DNA and RNA helicase	513
2918280956	180	26.7	3	56	3	57	1.4e-19	17.5	COG1335	Nicotinamidase-related amidase	205
2918280956	180	45.63	55	169	104	197	1.4e-19	46.6	COG1335	Nicotinamidase-related amidase	205
2918280957	234	91.19	2	233	24	292	2.1e-32	107.3	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918280960	662	99.69	10	660	3	641	0.0e+00	771	COG0187	DNA gyrase/topoisomerase IV, subunit B	635
2918280961	131	75.16	2	131	14	131	4.0e-45	147.8	COG1607	Acyl-CoA hydrolase	157
2918280963	129	68.64	9	113	32	112	1.6e-11	38.5	COG2919	Cell division protein FtsB	117
2918280964	338	92.18	2	338	15	344	0.0e+00	441.9	COG1071	TPP-dependent pyruvate or acetoin dehydrogenase subunit alpha	358
2918280965	465	99.07	141	464	2	322	0.0e+00	471.5	COG0022	Pyruvate/2-oxoglutarate/acetoin dehydrogenase complex, dehydrogenase (E1) component	324
2918280966	453	99.77	1	453	1	433	0.0e+00	489.8	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
2918280967	94	87.13	1	93	8	95	8.9e-22	71.9	COG1605	Chorismate mutase	101
2918280968	465	99.34	2	455	3	454	0.0e+00	577.9	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
2918280970	318	98.04	3	308	5	304	0.0e+00	466.6	COG0320	Lipoate synthase	306
2918280971	155	98.63	1	145	1	144	4.1e-52	170.2	COG2867	Ribosome association toxin PasT (RatA) of the RatAB toxin-antitoxin module	146
2918280972	167	95.09	1	162	5	159	6.3e-60	195.8	COG1546	Nicotinamide mononucleotide (NMN) deamidase PncC	162
2918280973	388	96.98	1	225	4	228	6.6e-72	235.1	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	230
2918280973	388	97.48	227	387	1	155	1.3e-63	207.7	COG0245	2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	159
2918280974	271	90.19	3	271	25	263	1.2e-31	104.8	COG4137	ABC-type uncharacterized transport system, permease component	265
2918280975	328	97.85	3	322	2	319	4.3e-110	362.4	COG0042	tRNA-dihydrouridine synthase	323
2918280976	365	95.87	1	353	12	359	2.6e-125	412.6	COG3852	Signal transduction histidine kinase, nitrogen specific	363
2918280977	481	98.07	1	479	3	460	0.0e+00	586.6	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2918280978	770	98.31	24	745	10	709	0.0e+00	768.1	COG5000	Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation	712
2918280979	466	98.5	1	462	4	463	0.0e+00	549.9	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2918280980	458	97.32	234	454	2	219	2.4e-109	146.2	COG0569	Trk K+ transport system, NAD-binding component	225
2918280980	458	98.66	1	230	2	222	2.4e-109	216.2	COG0569	Trk K+ transport system, NAD-binding component	225
2918280981	294	98.95	2	285	2	283	1.9e-80	265.3	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
2918280982	244	95.05	16	224	5	215	1.2e-35	117.8	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
2918280983	82	94.81	2	78	2	74	3.0e-36	117.5	COG1923	sRNA-binding regulator protein Hfq	77
2918280984	406	94.66	3	404	21	410	0.0e+00	458.3	COG2262	50S ribosomal subunit-associated GTPase HflX	411
2918280987	270	94.59	6	269	11	255	4.1e-54	178.1	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
2918280988	269	52.46	1	266	232	487	3.4e-80	265	COG3956	Uncharacterized conserved protein YabN, contains tetrapyrrole methylase and MazG-like pyrophosphatase domain	488
2918280989	211	63.05	15	192	30	157	4.1e-09	30.1	COG3271	Predicted double-glycine peptidase	201
2918280990	143	12.63	97	139	119	142	1.4e-03	6.1	COG3005	Tetraheme cytochrome c subunit of nitrate or TMAO reductase	190
2918280990	143	18.95	6	72	121	156	1.4e-03	6.3	COG3005	Tetraheme cytochrome c subunit of nitrate or TMAO reductase	190
2918280991	143	38.41	5	107	30	92	3.4e-04	15.3	COG2010	Cytochrome c, mono- and diheme variants	150
2918280992	151	25	4	141	14	61	6.2e-03	5.7	COG3658	Cytochrome b	192
2918280993	51	4.68	2	43	193	229	3.9e-03	10.2	COG1287	Asparagine N-glycosylation enzyme, membrane subunit Stt3	773
2918280994	124	56.55	17	109	61	142	1.1e-15	52.9	COG3212	Uncharacterized membrane protein YkoI	144
2918280995	219	99.14	1	219	1	230	2.8e-82	270	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918280996	455	88.58	76	455	40	388	5.4e-34	113	COG0642	Signal transduction histidine kinase	336
2918280997	391	60.54	4	165	12	123	3.6e-10	33.8	COG4461	Uncharacterized protein YPO0702	185
2918280998	258	97.07	1	258	3	267	4.6e-55	181.3	COG1235	Phosphoribosyl 1,2-cyclic phosphodiesterase	269
2918280999	261	98.83	1	256	2	255	2.4e-90	296.9	COG0084	Tat protein secretion system quality control protein TatD (DNase activity)	256
2918281000	516	97.67	1	516	4	549	0.0e+00	639.1	COG0143	Methionyl-tRNA synthetase	558
2918281002	156	69.7	4	146	50	164	5.6e-23	76.1	COG4731	Uncharacterized conserved protein, DUF2147 family	162
2918281003	212	98.08	2	209	2	205	3.2e-73	240.3	COG0125	Thymidylate kinase	208
2918281004	389	93.38	3	386	18	384	2.9e-117	386.5	COG1686	D-alanyl-D-alanine carboxypeptidase	389
2918281005	306	62.9	8	212	60	215	1.3e-64	212.7	COG0797	Rare lipoprotein A, peptidoglycan hydrolase digesting "naked" glycans, contains C-terminal SPOR domain	233
2918281006	263	98.27	16	255	2	228	3.4e-38	126.1	COG1434	Uncharacterized SAM-binding protein YcdF, DUF218 family	223
2918281007	652	88	163	648	50	423	1.3e-61	203.9	COG0840	Methyl-accepting chemotaxis protein	408
2918281008	883	99.66	2	883	2	881	0.0e+00	1259.6	COG0525	Valyl-tRNA synthetase	877
2918281009	233	99.57	11	232	1	233	3.8e-26	83.1	COG3827	Cell pole-organizing protein PopZ	231
2918281010	468	91.3	5	448	35	454	2.0e-70	232.5	COG1538	Outer membrane protein TolC	457
2918281011	108	92.98	3	108	8	113	8.6e-30	97.7	COG0607	Rhodanese-related sulfurtransferase	110
2918281012	218	96.21	7	218	2	204	1.6e-56	185.7	COG2518	Protein-L-isoaspartate O-methyltransferase	209
2918281015	70	24.51	1	65	63	125	1.1e-03	13.5	COG5662	Transmembrane transcriptional regulator (anti-sigma factor RsiW)	256
2918281018	336	86.85	7	332	46	362	1.5e-38	127.2	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
2918281019	202	78.49	43	194	13	147	1.4e-19	65	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2918281020	334	98.01	3	314	6	301	2.5e-109	359.5	COG0031	Cysteine synthase	300
2918281021	236	96.71	1	236	4	238	6.5e-77	252.9	COG2872	Ser-tRNA(Ala) deacylase AlaX (editing enzyme)	241
2918281022	290	96.17	2	288	11	286	2.4e-90	297	COG2897	3-mercaptopyruvate sulfurtransferase SseA, contains two rhodanese domains	285
2918281023	135	57.67	1	120	53	161	4.5e-18	60.3	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
2918281024	210	59.26	47	189	61	156	6.1e-10	34.1	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2918281025	361	98.34	5	361	3	357	1.4e-96	318.1	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
2918281026	258	99.17	16	256	2	241	5.0e-118	387.1	COG1126	ABC-type polar amino acid transport system, ATPase component	240
2918281027	367	91.67	135	365	19	227	6.1e-66	217	COG0765	ABC-type amino acid transport system, permease component	222
2918281028	399	96.73	2	399	14	397	0.0e+00	559	COG4597	ABC-type amino acid transport system, permease component	397
2918281029	340	87.63	1	270	9	256	9.3e-42	137.5	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918281030	392	98.74	1	389	5	396	1.8e-125	413.4	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
2918281031	141	94.64	4	113	6	111	4.7e-43	140	COG0139	Phosphoribosyl-AMP cyclohydrolase	111
2918281032	79	13.64	2	69	145	201	9.7e-04	12.5	COG1301	Na+/H+-dicarboxylate symporter	415
2918281038	410	99.8	18	410	2	510	6.4e-76	251.1	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
2918281039	250	98.23	20	244	2	223	4.2e-84	275.8	COG1136	ABC-type lipoprotein export system, ATPase component	226
2918281040	447	67.33	47	331	52	288	1.7e-47	156.4	COG1566	Multidrug resistance efflux pump	352
2918281041	156	95.24	30	156	3	122	4.1e-43	140.8	COG1430	Uncharacterized conserved membrane protein, UPF0127 family	126
2918281042	185	25	17	179	42	107	1.1e-03	13.7	COG1729	Periplasmic TolA-binding protein (function unknown)	262
2918281043	192	15.26	1	136	44	108	1.4e-04	15.4	COG4942	Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB	420
2918281045	375	91.07	3	333	8	323	2.5e-74	244.7	COG0123	Acetoin utilization deacetylase AcuC or a related deacetylase	340
2918281048	253	96.02	13	253	4	244	3.8e-68	224.2	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2918281049	253	94.96	1	247	12	256	1.3e-72	239	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2918281050	313	92.84	1	309	6	316	4.4e-58	191.7	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918281051	274	37.11	153	274	98	156	8.5e-20	47.7	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2918281051	274	95.6	1	145	5	156	8.5e-20	22.2	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2918281052	346	96.88	15	335	3	312	2.7e-105	346.3	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
2918281053	279	93.26	1	278	6	268	2.8e-80	263.8	COG0656	Aldo/keto reductase, related to diketogulonate reductase	280
2918281054	698	94.07	2	697	47	808	0.0e+00	476.1	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
2918281055	282	96.17	3	282	6	281	2.6e-59	195.5	COG2175	Taurine dioxygenase, alpha-ketoglutarate-dependent	286
2918281056	338	94.63	1	335	8	324	6.2e-39	128.7	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918281057	269	97.21	4	261	4	247	7.3e-91	298.6	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2918281058	259	96.51	1	258	7	255	1.2e-73	242.3	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2918281060	1019	78.21	1	239	2	220	9.6e-33	108.6	COG3629	DNA-binding transcriptional activator of the SARP family	280
2918281061	128	57.14	1	63	23	58	5.8e-21	36.5	COG5457	Uncharacterized conserved protein YjiS, DUF1127 family	63
2918281061	128	66.67	64	116	13	54	5.8e-21	31.2	COG5457	Uncharacterized conserved protein YjiS, DUF1127 family	63
2918281062	514	65	4	208	1	182	1.4e-25	84.5	COG3629	DNA-binding transcriptional activator of the SARP family	280
2918281062	514	96.61	232	503	7	291	1.7e-28	94.9	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918281063	203	71.53	68	202	34	131	7.1e-18	58.9	COG1765	Uncharacterized OsmC-related protein	137
2918281064	418	52.02	1	370	7	238	2.1e-48	160.1	COG2072	Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD	443
2918281065	385	89.93	4	383	2	367	5.2e-34	111.5	COG0644	Dehydrogenase (flavoprotein)	396
2918281066	152	77.36	14	149	30	152	1.8e-25	83.5	COG2030	Acyl dehydratase	159
2918281067	1049	99.8	1	1029	2	1013	0.0e+00	1230	COG0841	Multidrug efflux pump subunit AcrB	1009
2918281068	391	96.41	2	378	13	388	8.6e-73	240.1	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918281069	229	88.52	13	218	16	200	4.3e-22	74.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918281070	283	94.34	142	283	7	156	1.4e-18	62.2	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2918281071	215	90.43	8	214	12	200	2.7e-29	97.8	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918281072	271	99.25	1	270	2	266	7.8e-41	134.6	COG0725	ABC-type molybdate transport system, periplasmic component	258
2918281073	310	96.68	1	298	3	293	8.5e-54	177.8	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918281074	158	88.55	2	156	15	161	7.7e-47	153.2	COG1905	NADH:ubiquinone oxidoreductase 24 kD subunit (chain E)	160
2918281075	521	98.11	97	518	3	418	0.0e+00	549.7	COG1894	NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F)	424
2918281076	939	21.88	14	239	3	216	0.0e+00	276.5	COG3383	Predicted molibdopterin-dependent oxidoreductase YjgC	978
2918281076	939	70.86	231	937	262	954	0.0e+00	956.8	COG3383	Predicted molibdopterin-dependent oxidoreductase YjgC	978
2918281077	261	89.14	8	261	21	258	1.9e-74	244.8	COG1526	Formate dehydrogenase assembly factor FdhD	266
2918281078	278	97	14	278	7	265	3.4e-82	270.2	COG1526	Formate dehydrogenase assembly factor FdhD	266
2918281079	211	93.58	5	211	3	206	7.7e-81	265.4	COG2864	Cytochrome b subunit of formate dehydrogenase	218
2918281080	295	95.61	16	237	8	203	1.6e-58	192	COG0437	Fe-S-cluster-containing dehydrogenase component	203
2918281081	1020	99.88	2	1018	1	809	0.0e+00	675.6	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
2918281082	305	13.96	20	94	25	67	1.9e-63	25.6	COG3058	Formate dehydrogenase maturation protein FdhE	308
2918281082	305	66.23	83	305	102	305	1.9e-63	182.4	COG3058	Formate dehydrogenase maturation protein FdhE	308
2918281083	697	80.2	252	685	74	389	1.0e-57	191	COG0642	Signal transduction histidine kinase	336
2918281084	466	97	23	466	6	458	0.0e+00	526.1	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2918281085	119	53.6	9	115	25	91	5.4e-14	47.3	COG3293	Transposase	124
2918281087	223	89.22	1	214	12	218	7.4e-54	177.1	COG1802	DNA-binding transcriptional regulator, GntR family	230
2918281088	241	92.45	1	241	15	259	7.1e-54	177.5	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918281089	499	98.96	21	499	3	476	0.0e+00	517.4	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918281090	399	99.18	15	375	2	364	3.5e-41	135.8	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918281091	299	99.3	2	293	2	285	2.8e-101	333	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
2918281092	326	99.4	2	326	2	330	1.2e-95	315.3	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2918281093	466	88.38	1	463	56	557	9.5e-112	368.6	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2918281097	289	98.01	2	289	3	297	1.4e-68	226.2	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2918281098	329	97.52	2	321	7	321	1.2e-67	223	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918281099	241	99.21	1	238	3	254	1.9e-91	299.8	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2918281100	570	91.29	57	565	36	423	6.0e-60	197.7	COG0840	Methyl-accepting chemotaxis protein	408
2918281101	193	93.38	63	193	9	135	1.3e-21	71.9	COG4520	Surface antigen	136
2918281102	538	97.46	16	537	2	539	0.0e+00	521.1	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
2918281103	250	95.75	3	250	6	253	2.9e-35	116.4	COG0730	Uncharacterized membrane protein YfcA	258
2918281104	234	98.73	1	234	3	236	6.4e-92	301.6	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2918281105	91	86.87	1	91	11	96	3.5e-18	60.4	COG2388	Predicted acetyltransferase, GNAT superfamily	99
2918281106	206	94.74	3	205	4	201	1.3e-57	189	COG2860	Uncharacterized membrane protein YeiH	209
2918281107	232	87.86	1	232	1	246	2.0e-64	212.4	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
2918281110	279	12.44	4	59	99	125	2.9e-65	13.4	COG4711	Uncharacterized membrane protein	217
2918281110	279	99.08	52	279	2	216	2.9e-65	204.8	COG4711	Uncharacterized membrane protein	217
2918281111	191	90.12	2	185	10	164	1.3e-20	68.3	COG2137	SOS response regulatory protein OraA/RecX, interacts with RecA	174
2918281112	260	80	31	257	44	255	1.1e-14	48.1	COG1682	ABC-type polysaccharide/polyol phosphate export permease	263
2918281113	384	94.32	1	384	18	399	0.0e+00	497	COG4992	Acetylornithine/succinyldiaminopimelate/putrescine aminotransferase	404
2918281114	306	98.71	1	303	4	310	6.4e-122	401.3	COG0078	Ornithine carbamoyltransferase	310
2918281115	326	98.26	9	310	4	285	2.7e-89	293.8	COG1281	Redox-regulated molecular chaperone, HSP33 family	286
2918281117	629	13.18	260	336	94	149	2.0e-107	7.9	COG0840	Methyl-accepting chemotaxis protein	408
2918281117	629	14.35	171	284	82	142	2.0e-107	9.4	COG0840	Methyl-accepting chemotaxis protein	408
2918281117	629	78.12	318	628	94	425	2.0e-107	343.9	COG0840	Methyl-accepting chemotaxis protein	408
2918281118	434	99.52	6	426	3	419	0.0e+00	687.7	COG0499	S-adenosylhomocysteine hydrolase	420
2918281120	247	73.71	21	235	57	227	5.4e-28	93.1	COG0671	Membrane-associated phospholipid phosphatase	232
2918281123	306	97.2	1	306	2	313	5.1e-51	168.7	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2918281124	422	99.28	4	422	3	414	2.3e-126	416.5	COG3395	Uncharacterized conserved protein YgbK, DUF1537 family	413
2918281125	261	98.85	1	259	1	257	6.8e-108	354.7	COG3622	Hydroxypyruvate isomerase	260
2918281130	333	95.85	64	332	5	258	2.0e-64	211.7	COG2220	L-ascorbate metabolism protein UlaG, beta-lactamase superfamily	258
2918281131	923	99.56	4	923	5	913	0.0e+00	1151.1	COG2352	Phosphoenolpyruvate carboxylase	910
2918281133	546	93.44	322	538	10	180	4.7e-54	175.2	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2918281135	71	97.22	1	71	3	72	3.7e-20	66.8	COG2900	Uncharacterized coiled-coil protein SlyX (sensitive to lysis X)	72
2918281137	145	32.48	56	141	15	52	7.8e-03	10	COG3462	Uncharacterized membrane protein	117
2918281139	722	91.06	230	713	37	423	3.2e-60	198.7	COG0840	Methyl-accepting chemotaxis protein	408
2918281140	258	83.03	24	247	37	217	6.1e-34	112	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2918281143	149	37.7	10	43	12	34	2.3e-03	12.4	COG0199	Ribosomal protein S14	61
2918281143	149	45.9	80	125	15	42	2.3e-03	3.7	COG0199	Ribosomal protein S14	61
2918281145	60	92.86	1	52	4	55	5.5e-28	91.2	COG0401	Uncharacterized membrane protein YqaE, homolog of Blt101, UPF0057 family	56
2918281147	122	82.71	1	121	7	116	3.6e-22	73.3	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918281150	135	92.48	12	135	6	128	5.4e-21	69.5	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918281151	2099	81.22	1250	1676	69	388	5.5e-72	238.2	COG0642	Signal transduction histidine kinase	336
2918281151	2099	87.22	1712	1835	8	123	1.4e-55	45.5	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918281151	2099	89.29	997	1077	2	76	0.0e+00	28.6	COG2770	HAMP domain	83
2918281151	2099	91.67	1089	1190	2	78	0.0e+00	31	COG2770	HAMP domain	83
2918281151	2099	92.48	1975	2099	6	128	1.4e-55	105.4	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918281151	2099	93.23	1830	1957	6	129	1.4e-55	24.9	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918281151	2099	95.24	169	249	2	81	0.0e+00	48	COG2770	HAMP domain	83
2918281151	2099	95.24	537	617	2	81	0.0e+00	45	COG2770	HAMP domain	83
2918281151	2099	95.24	629	709	2	81	0.0e+00	47.5	COG2770	HAMP domain	83
2918281151	2099	95.24	721	801	2	81	0.0e+00	42.6	COG2770	HAMP domain	83
2918281151	2099	96.43	261	341	2	82	0.0e+00	46.7	COG2770	HAMP domain	83
2918281151	2099	96.43	353	433	2	82	0.0e+00	51.8	COG2770	HAMP domain	83
2918281151	2099	96.43	445	525	2	82	0.0e+00	49.9	COG2770	HAMP domain	83
2918281151	2099	96.43	813	893	2	82	0.0e+00	51.8	COG2770	HAMP domain	83
2918281151	2099	96.43	905	985	2	82	0.0e+00	46.7	COG2770	HAMP domain	83
2918281152	689	66.75	165	543	128	390	1.4e-54	180.6	COG0642	Signal transduction histidine kinase	336
2918281152	689	93.23	6	135	5	128	2.0e-45	89.6	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918281152	689	93.23	557	685	5	128	2.0e-45	61.7	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918281153	127	93.23	5	127	4	127	3.1e-18	60.6	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918281154	560	92.98	274	545	12	223	3.0e-66	217	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
2918281155	273	91.86	1	227	2	159	4.0e-18	55.8	COG0622	Predicted phosphodiesterase	172
2918281156	381	78.31	1	371	15	339	3.9e-46	152.3	COG3919	Predicted ATP-dependent carboligase, ATP-grasp superfamily	415
2918281157	393	9.11	13	86	38	74	6.5e-11	5	COG5653	Acetyltransferase involved in cellulose biosynthesis, CelD/BcsL family	406
2918281157	393	35.47	145	349	191	334	6.5e-11	30.5	COG5653	Acetyltransferase involved in cellulose biosynthesis, CelD/BcsL family	406
2918281160	335	98.02	7	334	4	350	7.3e-94	308.8	COG0306	Phosphate/sulfate permease	326
2918281161	217	98.16	1	216	4	216	3.8e-42	138.7	COG1392	Uncharacterized conserved protein YkaA, distantly related to PhoU, UPF0111/DUF47 family	217
2918281162	350	91.33	2	348	21	315	1.4e-106	349.5	COG4111	Uncharacterized conserved protein	322
2918281163	170	75.94	4	170	13	173	1.1e-52	173.3	COG0684	Regulator of RNase E activity RraA	210
2918281164	96	10.38	2	94	63	116	4.5e-04	13.6	COG0815	Apolipoprotein N-acyltransferase	518
2918281165	861	99.65	1	861	2	850	0.0e+00	1512.2	COG1049	Aconitase B	852
2918281167	141	97.74	9	141	3	132	2.2e-28	93.7	COG3766	Uncharacterized membrane protein YjfL, UPF0719 family	133
2918281168	256	15.92	16	255	694	879	1.3e-06	20.8	COG1196	Chromosome segregation ATPase	1163
2918281169	141	71.51	1	139	21	143	1.3e-15	52.5	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2918281170	1051	18.04	940	1046	413	513	1.9e-32	45.1	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918281170	1051	36.07	55	477	343	544	1.9e-32	29.5	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918281170	1051	78.04	353	954	21	457	1.9e-32	25.6	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918281171	329	98.34	2	299	2	297	3.1e-71	235	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918281172	269	83.02	1	268	44	307	9.7e-61	200.6	COG0657	Acetyl esterase/lipase	312
2918281173	388	97.44	1	376	8	387	1.2e-57	190.4	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918281174	1060	99.9	2	1039	1	1013	0.0e+00	1189.4	COG0841	Multidrug efflux pump subunit AcrB	1009
2918281175	588	85.79	154	588	53	390	3.7e-46	153.2	COG0642	Signal transduction histidine kinase	336
2918281177	208	94.03	7	73	3	65	2.6e-24	52.5	COG1278	Cold shock protein, CspA family	67
2918281177	208	94.03	141	208	4	66	2.6e-24	25.5	COG1278	Cold shock protein, CspA family	67
2918281179	464	48.3	248	452	10	194	6.0e-24	19.7	COG0477	MFS family permease	338
2918281179	464	62.92	28	294	8	248	6.0e-24	62.6	COG0477	MFS family permease	338
2918281181	385	91.73	1	246	21	253	4.2e-76	249.8	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
2918281182	665	99.65	48	617	3	569	0.0e+00	773.2	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
2918281183	216	89.2	4	214	23	212	2.1e-66	217.8	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
2918281184	146	92.86	26	137	9	112	3.6e-43	140.3	COG3125	Heme/copper-type cytochrome/quinol oxidase, subunit 4	111
2918281185	258	92.52	2	250	12	246	1.0e-80	265.2	COG3346	Cytochrome oxidase assembly protein ShyY1	252
2918281186	425	97.16	24	413	3	379	3.6e-74	244.8	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918281187	401	97.71	6	396	7	390	0.0e+00	452.4	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
2918281188	173	58.45	9	162	86	213	7.0e-05	15.1	COG2345	Predicted transcriptional regulator, ArsR family	218
2918281189	248	98.73	15	248	3	236	2.5e-94	309.4	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2918281190	257	98.82	3	252	3	253	7.3e-99	324.7	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2918281191	352	95.36	17	331	9	316	6.5e-84	276.2	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918281192	305	98.01	4	305	4	298	8.8e-77	253	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2918281193	373	95.36	13	371	6	354	2.6e-67	221.8	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918281195	383	97.35	43	352	8	301	1.8e-72	238.4	COG0031	Cysteine synthase	300
2918281196	130	93.38	5	130	7	133	4.9e-35	114.9	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
2918281197	156	95.57	1	155	5	155	2.9e-42	139	COG1522	DNA-binding transcriptional regulator, Lrp family	154
2918281198	393	98.48	2	392	5	393	1.6e-111	367.1	COG2814	Predicted arabinose efflux permease, MFS family	394
2918281199	144	55.92	25	143	2	119	9.3e-18	59	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918281200	1948	63.1	94	158	31	83	1.8e-124	15.5	COG2770	HAMP domain	83
2918281200	1948	81.73	1072	1493	67	388	9.4e-74	243.3	COG0642	Signal transduction histidine kinase	336
2918281200	1948	83.46	1658	1789	6	116	2.2e-63	25.6	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918281200	1948	89.29	814	894	2	76	1.8e-124	26.6	COG2770	HAMP domain	83
2918281200	1948	90.23	1537	1660	6	125	2.2e-63	65.2	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918281200	1948	91.67	906	1008	2	78	1.8e-124	30.7	COG2770	HAMP domain	83
2918281200	1948	93.98	1804	1933	6	130	2.2e-63	110.4	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918281200	1948	96.43	170	250	2	82	1.8e-124	52	COG2770	HAMP domain	83
2918281200	1948	96.43	262	342	2	82	1.8e-124	46.7	COG2770	HAMP domain	83
2918281200	1948	96.43	354	434	2	82	1.8e-124	45.9	COG2770	HAMP domain	83
2918281200	1948	96.43	446	526	2	82	1.8e-124	49.3	COG2770	HAMP domain	83
2918281200	1948	96.43	538	618	2	82	1.8e-124	49.6	COG2770	HAMP domain	83
2918281200	1948	96.43	630	710	2	82	1.8e-124	48.9	COG2770	HAMP domain	83
2918281200	1948	96.43	722	802	2	82	1.8e-124	51.6	COG2770	HAMP domain	83
2918281201	717	67.51	146	572	127	392	1.6e-54	180.2	COG0642	Signal transduction histidine kinase	336
2918281203	227	94.62	2	226	12	222	1.0e-45	150.6	COG1418	HD superfamily phosphodieaserase, includes HD domain of RNase Y	222
2918281205	179	59.25	1	178	32	204	4.5e-30	99.3	COG1284	Uncharacterized membrane-anchored protein YitT, contains DUF161 and DUF2179 domains	289
2918281208	341	97.41	1	323	1	301	1.5e-75	248.7	COG1893	Ketopantoate reductase	307
2918281209	147	93.25	3	126	12	163	4.6e-20	66.9	COG0517	CBS domain	117
2918281210	129	9.73	1	101	5	36	2.7e-05	18.3	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
2918281211	560	58.45	29	556	2	461	9.8e-108	355.6	COG0574	Phosphoenolpyruvate synthase/pyruvate phosphate dikinase	740
2918281212	310	90.49	1	310	3	316	1.6e-99	327.8	COG0123	Acetoin utilization deacetylase AcuC or a related deacetylase	340
2918281213	149	92.64	2	126	12	162	4.3e-27	89.7	COG0517	CBS domain	117
2918281214	146	60.49	6	139	53	150	6.1e-07	24.8	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2918281215	247	96.53	1	247	5	254	1.2e-32	107.9	COG0730	Uncharacterized membrane protein YfcA	258
2918281216	340	97.41	1	324	1	301	6.9e-76	249.8	COG1893	Ketopantoate reductase	307
2918281217	390	100	2	374	1	363	0.0e+00	489.6	COG3288	NAD/NADP transhydrogenase alpha subunit	356
2918281218	150	28.93	8	150	98	202	1.6e-25	84.9	COG3288	NAD/NADP transhydrogenase alpha subunit	356
2918281219	465	99.15	1	462	4	469	0.0e+00	725	COG1282	NAD/NADP transhydrogenase beta subunit	463
2918281220	215	85.78	1	212	18	216	1.9e-44	146.3	COG1802	DNA-binding transcriptional regulator, GntR family	230
2918281221	573	96.76	8	565	3	539	0.0e+00	443.6	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
2918281222	424	98	1	415	7	399	1.1e-125	414.3	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2918281223	580	81.93	22	178	26	161	2.0e-23	76.6	COG1905	NADH:ubiquinone oxidoreductase 24 kD subunit (chain E)	160
2918281223	580	94.81	166	574	21	422	1.6e-125	412.9	COG1894	NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F)	424
2918281224	917	95.4	1	917	6	938	0.0e+00	890.1	COG3383	Predicted molibdopterin-dependent oxidoreductase YjgC	978
2918281225	274	99.59	25	270	1	245	9.7e-74	241.9	COG1414	DNA-binding transcriptional regulator, IclR family	246
2918281226	444	53.52	224	440	5	209	2.4e-22	27.8	COG0477	MFS family permease	338
2918281226	444	67.62	16	278	9	267	2.4e-22	47.9	COG0477	MFS family permease	338
2918281228	333	100	7	331	1	331	4.0e-104	343.1	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2918281229	433	52.48	221	426	4	204	7.7e-19	20.7	COG0477	MFS family permease	338
2918281229	433	63.19	12	250	31	272	7.7e-19	44.8	COG0477	MFS family permease	338
2918281230	420	99.29	1	420	3	421	0.0e+00	572.4	COG2379	Glycerate-2-kinase	422
2918281231	302	100	1	284	1	286	2.3e-115	379.3	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
2918281232	273	99.23	9	268	1	258	4.0e-118	388.2	COG3622	Hydroxypyruvate isomerase	260
2918281233	300	99.59	26	271	1	245	1.1e-79	261.4	COG1414	DNA-binding transcriptional regulator, IclR family	246
2918281234	589	98.48	1	588	1	583	0.0e+00	1182.7	COG3960	Glyoxylate carboligase	592
2918281235	204	87.68	2	203	8	192	1.5e-43	142.8	COG0352	Thiamine monophosphate synthase	211
2918281236	229	90.52	1	226	11	220	3.6e-50	165.1	COG1802	DNA-binding transcriptional regulator, GntR family	230
2918281237	493	99.37	1	470	3	477	0.0e+00	556.5	COG0469	Pyruvate kinase	477
2918281238	240	76.16	1	186	14	144	5.9e-15	49.9	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2918281239	191	96.3	21	181	2	157	2.4e-41	136.1	COG1763	Molybdopterin-guanine dinucleotide biosynthesis protein	161
2918281242	162	95.68	22	159	5	137	4.2e-28	92.5	COG0824	Acyl-CoA thioesterase FadM	137
2918281243	172	40.31	17	172	29	182	4.3e-34	112.3	COG3448	CBS-domain-containing membrane protein	382
2918281244	142	48.76	4	127	123	240	3.1e-18	60.7	COG2202	PAS domain	232
2918281245	416	98.75	1	416	6	401	1.9e-126	416.7	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2918281246	86	54.14	7	86	27	98	2.1e-04	15.9	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918281247	641	91.1	227	608	33	503	5.1e-60	197.2	COG0366	Glycosidase	505
2918281249	836	64.4	331	833	217	643	2.2e-107	354	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2918281250	240	89.68	1	226	5	230	1.2e-42	140.5	COG1381	Recombinational DNA repair protein (RecF pathway)	251
2918281251	752	86.35	1	751	7	708	0.0e+00	816.1	COG0188	DNA gyrase/topoisomerase IV, subunit A	804
2918281252	363	99.45	1	357	1	361	0.0e+00	554.5	COG4663	TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component	363
2918281254	501	97.76	4	458	3	439	0.0e+00	696.7	COG4664	TRAP-type mannitol/chloroaromatic compound transport system, large permease component	447
2918281255	178	94.51	1	178	3	174	1.6e-71	234.2	COG4665	TRAP-type mannitol/chloroaromatic compound transport system, small permease component	182
2918281256	246	95.26	3	246	6	246	2.3e-79	261	COG2935	Arginyl-tRNA--protein-N-Asp/Glu arginylyltransferase	253
2918281257	325	99.04	3	318	1	310	2.0e-77	255.3	COG2307	Uncharacterized conserved protein, Alpha-E superfamily	313
2918281258	494	95.9	12	491	11	478	0.0e+00	648.6	COG2308	Uncharacterized conserved protein, circularly permuted ATPgrasp superfamily	488
2918281259	341	98.52	12	337	4	269	9.9e-62	201.6	COG1360	Flagellar motor protein MotB	244
2918281260	159	85.95	1	158	10	168	3.9e-45	148.3	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
2918281261	405	97.98	1	336	5	343	1.6e-109	360.8	COG1171	Threonine dehydratase	347
2918281262	802	98.33	1	790	1	766	0.0e+00	570.7	COG2366	Acyl-homoserine lactone (AHL) acylase PvdQ	768
2918281264	201	98.51	1	201	1	199	3.4e-68	223.8	COG1279	Arginine exporter protein ArgO	202
2918281265	294	96.35	2	293	2	291	3.2e-44	146.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918281266	754	67.01	315	622	128	391	2.0e-55	183.7	COG0642	Signal transduction histidine kinase	336
2918281266	754	97.46	1	233	6	235	5.2e-65	213.4	COG3300	MHYT domain, NO-binding membrane sensor	236
2918281269	283	93.22	17	282	12	286	6.0e-34	112.5	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918281270	66	24.46	3	56	40	84	1.0e-02	9.8	COG3216	Uncharacterized conserved protein, DUF2062 family	184
2918281271	281	97.31	24	281	4	256	2.4e-80	264	COG0030	16S rRNA A1518 and A1519 N6-dimethyltransferase RsmA/KsgA/DIM1 (may also have DNA glycosylase/AP lyase activity)	259
2918281272	118	38.06	23	108	48	98	1.1e-09	32.5	COG3335	Transposase	132
2918281273	1020	14.46	902	1015	415	495	1.3e-43	42.5	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918281273	1020	33.57	4	227	294	481	1.3e-43	64.2	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918281273	1020	65.18	220	909	89	453	1.3e-43	37.8	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918281274	238	98.71	2	227	2	230	3.2e-52	171.6	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918281275	658	80.46	267	655	73	389	5.0e-53	175.8	COG0642	Signal transduction histidine kinase	336
2918281276	366	99.45	1	361	1	361	0.0e+00	552.6	COG4663	TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component	363
2918281277	460	95.69	16	440	4	403	0.0e+00	531.1	COG1301	Na+/H+-dicarboxylate symporter	415
2918281281	558	72.4	18	264	66	288	1.9e-28	93.8	COG0223	Methionyl-tRNA formyltransferase	307
2918281281	558	88.3	280	531	7	240	1.8e-26	87.8	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918281282	381	99.46	1	372	1	365	0.0e+00	499.8	COG0409	Hydrogenase maturation factor	364
2918281283	213	24.81	11	168	30	94	1.2e-04	16.1	COG3103	Uncharacterized conserved protein YgiM, contains N-terminal SH3 domain, DUF1202 family	205
2918281284	645	8.19	9	113	25	95	1.2e-28	2.1	COG0308	Aminopeptidase N	859
2918281284	645	43.02	131	492	158	530	1.2e-28	89.2	COG0308	Aminopeptidase N	859
2918281285	220	90.53	34	220	10	181	2.1e-64	211.1	COG3703	Cation transport regulator ChaC	190
2918281286	337	96.45	1	335	13	338	1.9e-13	41.8	COG4093	Uncharacterized protein	338
2918281288	721	55.98	2	301	141	346	7.3e-23	75.9	COG0457	Tetratricopeptide (TPR) repeat	291
2918281289	890	99.79	3	890	2	472	6.2e-73	233.7	COG1749	Flagellar hook protein FlgE	423
2918281290	469	29.59	282	469	414	587	5.8e-62	67.5	COG1256	Flagellar hook-associated protein FlgK	552
2918281290	469	49.83	1	304	1	293	5.8e-62	143.6	COG1256	Flagellar hook-associated protein FlgK	552
2918281291	720	21.13	5	96	7	88	3.2e-12	17	COG1344	Flagellin and related hook-associated protein FlgL	360
2918281291	720	70.1	202	720	114	385	3.2e-12	22.4	COG1344	Flagellin and related hook-associated protein FlgL	360
2918281292	171	73.91	14	115	30	114	1.2e-09	32.6	COG5442	Flagellar biosynthesis regulator FlaF	115
2918281293	336	26.47	3	107	3	92	2.4e-43	59.8	COG0859	ADP-heptose:LPS heptosyltransferase	334
2918281293	336	45.29	103	314	162	315	2.4e-43	82	COG0859	ADP-heptose:LPS heptosyltransferase	334
2918281294	372	99.73	1	362	1	364	1.1e-54	180.6	COG0795	Lipopolysaccharide export LptBFGC system, permease protein LptF	364
2918281296	257	34.26	3	216	3	125	6.1e-12	39.8	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
2918281297	533	63.71	15	384	140	390	1.1e-56	187.5	COG0642	Signal transduction histidine kinase	336
2918281297	533	87.97	396	525	7	123	1.8e-13	43.8	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918281299	309	96.57	1	307	3	312	1.2e-79	262.7	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2918281300	295	98.67	5	293	2	298	5.0e-60	198.4	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918281301	250	94.98	1	247	7	252	6.3e-07	23.3	COG0730	Uncharacterized membrane protein YfcA	258
2918281302	143	90.62	1	143	5	149	1.3e-21	72	COG0680	Ni,Fe-hydrogenase maturation factor	160
2918281303	552	98.5	1	531	8	534	0.0e+00	540.1	COG1283	Na+/phosphate symporter	533
2918281304	302	94.35	16	302	12	295	6.5e-43	141.6	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918281305	299	91.69	16	297	1	276	1.5e-59	196.7	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918281306	430	96.26	2	430	3	439	1.1e-98	325.7	COG3259	Coenzyme F420-reducing hydrogenase, alpha subunit	441
2918281307	119	82.95	1	118	14	120	1.6e-40	132.7	COG2852	Very-short-patch-repair endonuclease	129
2918281308	258	86.75	3	243	5	220	2.6e-47	155.6	COG1941	Coenzyme F420-reducing hydrogenase, gamma subunit	247
2918281309	286	96.5	13	279	7	254	3.4e-48	158.4	COG0543	NAD(P)H-flavin reductase	252
2918281310	157	51.38	10	156	30	141	2.6e-10	34.7	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2918281311	392	66.94	227	391	28	110	1.2e-08	24.5	COG1145	Ferredoxin	99
2918281312	272	87.84	1	271	7	230	7.1e-10	32.5	COG1462	Curli biogenesis system outer membrane secretion channel CsgG	252
2918281315	151	93.79	5	149	6	141	3.5e-40	131.8	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
2918281317	220	99.13	1	220	3	229	3.7e-56	184.8	COG3128	Predicted 2-oxoglutarate- and Fe(II)-dependent dioxygenase YbiX	229
2918281318	613	98.82	13	588	5	589	3.4e-91	301.1	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
2918281319	381	76.54	16	311	16	289	1.8e-37	123.6	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
2918281320	226	17.72	91	161	166	207	1.7e-15	36.5	COG0775	Nucleoside phosphorylase	234
2918281320	226	19.41	27	119	73	118	1.7e-15	15.1	COG0775	Nucleoside phosphorylase	234
2918281321	143	92.05	1	140	12	150	3.2e-32	105.9	COG4704	Uncharacterized conserved protein, DUF2141 family	151
2918281322	643	7.93	13	81	137	177	2.4e-88	1.1	COG1657	Squalene cyclase	517
2918281322	643	98.84	109	643	2	512	2.4e-88	288.4	COG1657	Squalene cyclase	517
2918281323	886	9.25	16	108	13	80	1.2e-60	18	COG1033	Predicted exporter protein, RND superfamily	727
2918281323	886	23.81	671	878	559	733	1.2e-60	85.6	COG1033	Predicted exporter protein, RND superfamily	727
2918281323	886	37.41	226	533	178	452	1.2e-60	97.2	COG1033	Predicted exporter protein, RND superfamily	727
2918281325	365	35.54	246	362	100	158	5.3e-04	14.4	COG4304	Uncharacterized protein	166
2918281326	211	96.53	6	204	6	200	1.1e-24	81.9	COG2854	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic MlaC component	202
2918281327	321	95.95	3	320	5	312	8.5e-59	193.9	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2918281328	301	94.35	12	298	12	295	4.3e-38	125.7	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918281329	281	57.69	19	176	2	76	5.0e-13	44.3	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918281330	283	97.63	15	283	7	294	6.2e-47	154.9	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918281332	266	55.91	4	262	54	209	2.5e-19	64.6	COG0500	SAM-dependent methyltransferase	257
2918281333	253	89.42	2	252	31	292	1.0e-21	72	COG0842	ABC-type multidrug transport system, permease component	286
2918281334	308	99.35	1	306	2	305	2.7e-87	287.6	COG1131	ABC-type multidrug transport system, ATPase component	293
2918281335	356	93.23	102	356	15	262	4.6e-71	233.3	COG2375	NADPH-dependent ferric siderophore reductase, contains FAD-binding and SIP domains	265
2918281336	283	97.29	7	260	2	252	3.1e-64	211.2	COG1120	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	258
2918281337	151	44.18	1	150	186	333	5.5e-48	158.3	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
2918281338	187	42.69	18	173	5	147	3.1e-28	93.2	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
2918281339	391	88.89	20	355	37	324	4.2e-36	119.3	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
2918281340	774	99.25	21	774	7	795	3.2e-105	348.2	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2918281341	302	79.55	172	301	21	125	3.9e-27	88.4	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918281342	416	44.65	217	414	16	186	8.5e-21	24.9	COG0477	MFS family permease	338
2918281342	416	59.27	15	246	3	229	8.5e-21	46.3	COG0477	MFS family permease	338
2918281343	224	94.74	1	204	7	168	6.6e-13	39.1	COG3652	Predicted outer membrane protein	170
2918281344	643	99.84	1	643	1	636	0.0e+00	549.8	COG4548	Nitric oxide reductase activation protein	637
2918281345	268	72.42	13	265	44	282	1.3e-45	150.5	COG0714	MoxR-like ATPase	329
2918281346	449	64.3	1	439	245	705	0.0e+00	486.8	COG3256	Nitric oxide reductase large subunit	717
2918281347	150	51.83	16	148	54	138	7.6e-06	20.5	COG2010	Cytochrome c, mono- and diheme variants	150
2918281348	354	19.42	237	332	389	482	8.4e-23	12.8	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
2918281348	354	49.17	3	269	3	240	8.4e-23	64.6	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
2918281349	540	99.25	1	534	3	533	0.0e+00	618	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
2918281351	382	98.2	3	380	6	386	4.6e-62	204.9	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918281353	232	98.62	2	232	4	218	1.8e-63	208.6	COG3047	Outer membrane protein W	213
2918281354	144	47.85	70	144	3	80	7.3e-25	50.7	COG0517	CBS domain	117
2918281354	144	58.28	2	78	10	104	7.3e-25	39	COG0517	CBS domain	117
2918281355	215	96.68	1	214	1	204	1.7e-58	192.1	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918281356	596	96.99	29	461	9	395	1.8e-102	336.1	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918281357	775	19.45	319	458	183	246	3.4e-88	20.6	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
2918281357	775	72.83	457	760	16	208	4.7e-33	108.6	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918281357	775	89.06	1	330	1	293	3.4e-88	267.9	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
2918281358	379	99.75	1	379	1	393	4.6e-129	425.5	COG0183	Acetyl-CoA acetyltransferase	392
2918281359	161	87.12	28	157	1	115	8.7e-28	91.7	COG0789	DNA-binding transcriptional regulator, MerR family	124
2918281361	68	26.52	4	68	6	66	2.0e-03	12.3	COG0081	Ribosomal protein L1	228
2918281362	1601	93.26	41	1601	108	1630	0.0e+00	1031.3	COG2373	Uncharacterized conserved protein YfaS, alpha-2-macroglobulin family	1621
2918281363	544	72.34	167	544	101	385	8.8e-71	234.2	COG0642	Signal transduction histidine kinase	336
2918281364	387	96.97	5	387	9	392	2.2e-98	324.4	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
2918281367	282	90.11	12	281	25	270	4.9e-89	293	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
2918281368	667	99.11	1	636	3	673	1.2e-80	265.6	COG2982	Uncharacterized protein involved in outer membrane biogenesis	648
2918281370	441	38.6	241	398	18	83	5.0e-03	9.8	COG3652	Predicted outer membrane protein	170
2918281372	154	75	50	114	4	69	5.4e-06	20.4	COG1873	Sporulation protein YlmC, PRC-barrel domain family	87
2918281373	308	97.34	11	297	5	297	2.2e-41	136.6	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918281374	400	98.5	1	400	7	401	0.0e+00	529.4	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2918281375	401	98.75	15	400	4	397	1.8e-101	334.6	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918281376	309	98.34	1	301	1	296	1.7e-64	212.9	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918281377	369	98.87	8	368	3	351	1.2e-127	420.6	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
2918281378	348	91.53	1	348	13	358	9.7e-68	223.5	COG0687	Spermidine/putrescine-binding periplasmic protein	363
2918281379	420	25.35	18	131	10	82	3.3e-86	4.9	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
2918281379	420	76.04	138	417	61	279	3.3e-86	279.7	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
2918281380	277	96.63	8	273	7	264	4.3e-85	279.6	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
2918281381	328	96.08	1	328	9	327	2.0e-53	176.4	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
2918281382	199	77.69	14	143	2	102	1.0e-16	56.2	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918281383	486	98.96	12	486	2	475	0.0e+00	619.6	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918281384	428	95.96	1	426	18	445	0.0e+00	564.3	COG0160	4-aminobutyrate aminotransferase or related aminotransferase	447
2918281385	371	88.79	2	365	37	329	1.3e-62	205.7	COG3608	Predicted deacylase	331
2918281386	404	97.28	1	404	5	398	0.0e+00	483.7	COG4992	Acetylornithine/succinyldiaminopimelate/putrescine aminotransferase	404
2918281387	323	91.26	2	311	25	306	3.8e-78	257.1	COG0010	Arginase family enzyme	305
2918281388	142	91.77	1	141	6	150	1.4e-26	88	COG1522	DNA-binding transcriptional regulator, Lrp family	154
2918281389	356	96.97	15	268	2	257	8.9e-47	154.5	COG1192	Cellulose biosynthesis protein BcsQ	259
2918281390	486	96.65	13	484	3	463	1.3e-110	364.8	COG4529	Uncharacterized NAD(P)/FAD-binding protein YdhS	474
2918281391	194	96.34	3	191	2	185	7.0e-43	141.1	COG2249	Putative NADPH-quinone reductase (modulator of drug activity B)	189
2918281394	434	97.34	9	198	4	186	9.0e-38	124.2	COG3778	Uncharacterized protein YmfQ in lambdoid prophage, DUF2313 family	188
2918281395	351	98.87	5	350	2	352	1.4e-80	265.3	COG3299	Uncharacterized phage protein gp47/JayE	353
2918281396	147	78.52	16	145	24	129	6.6e-28	91.7	COG4381	Mu-like prophage protein gp46	135
2918281398	304	57	8	86	31	87	1.5e-09	31.8	COG4104	Zn-binding Pro-Ala-Ala-Arg (PAAR) domain, incolved in TypeVI secretion	98
2918281399	164	68.47	1	158	2	140	3.3e-41	135.5	COG4384	Mu-like prophage protein gp45	203
2918281400	356	91.45	1	351	1	353	3.3e-72	237.7	COG4379	Mu-like prophage tail protein gpP	386
2918281406	496	100	1	492	1	487	0.0e+00	581.6	COG4386	Mu-like prophage tail sheath protein gpL	487
2918281410	218	58.01	2	218	94	227	3.1e-12	41.2	COG2932	Phage repressor protein C, contains Cro/C1-type HTH and peptisase s24 domains	214
2918281412	38	10.77	1	38	222	256	1.3e-10	35.9	COG3491	Isopenicillin N synthase and related dioxygenases	322
2918281414	216	93.3	1	215	11	205	5.1e-41	135	COG0400	Predicted esterase	207
2918281415	72	27.12	1	61	122	169	2.9e-03	12.7	COG1592	Rubrerythrin	166
2918281416	476	90.13	65	215	13	149	3.5e-63	205.8	COG5616	TolB amino-terminal domain (function unknown)	152
2918281417	166	74.39	2	138	42	163	2.2e-08	28.4	COG2010	Cytochrome c, mono- and diheme variants	150
2918281418	339	69.58	5	270	45	275	9.5e-38	124.7	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
2918281419	705	84.77	198	696	56	389	1.8e-77	255.3	COG0642	Signal transduction histidine kinase	336
2918281420	424	98.27	12	424	6	402	0.0e+00	433	COG0162	Tyrosyl-tRNA synthetase	401
2918281422	827	85.53	118	474	56	392	3.2e-52	173.2	COG0642	Signal transduction histidine kinase	336
2918281422	827	97.67	534	826	4	297	7.1e-29	95.3	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
2918281423	224	98.71	1	222	1	229	5.1e-70	230	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918281424	276	79.87	1	269	23	149	4.3e-13	35.9	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2918281425	214	78.12	2	214	18	217	2.8e-48	158.9	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
2918281426	509	98.81	1	503	1	498	0.0e+00	659	COG3333	TctA family transporter	504
2918281428	325	97.18	6	325	10	319	6.3e-92	302.6	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918281429	325	98.12	6	325	7	319	4.1e-89	293.4	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918281430	263	98.49	1	260	5	265	1.8e-83	274.6	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918281431	455	88.83	245	450	5	179	9.4e-77	47.3	COG2059	Chromate transport protein ChrA	195
2918281431	455	90.86	1	214	4	182	9.4e-77	210.1	COG2059	Chromate transport protein ChrA	195
2918281432	494	90.25	1	471	15	449	3.3e-32	106.1	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
2918281433	481	82.67	258	481	37	222	8.7e-70	228.8	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
2918281434	434	85.78	38	420	51	418	6.6e-32	105.3	COG3307	O-antigen ligase	424
2918281436	396	97.31	7	368	9	406	3.7e-43	143.2	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918281437	385	95.84	1	356	13	404	7.5e-48	158.6	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918281438	302	60.07	19	271	23	183	1.4e-11	38.3	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
2918281439	97	95.06	10	92	5	81	2.7e-14	47.6	COG0236	Acyl carrier protein	80
2918281440	513	95.77	2	513	13	556	3.9e-125	412.8	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2918281441	668	95.99	1	635	1	526	0.0e+00	451.4	COG0367	Asparagine synthetase B (glutamine-hydrolyzing)	542
2918281442	335	94.16	13	327	2	259	3.3e-64	210.6	COG0171	NH3-dependent NAD+ synthetase	268
2918281443	368	41.36	11	150	42	108	3.3e-05	15.4	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2918281447	324	96.99	1	324	8	329	7.0e-88	289.7	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
2918281448	652	89.41	174	647	45	424	1.5e-50	167.5	COG0840	Methyl-accepting chemotaxis protein	408
2918281449	165	66.41	33	162	32	118	5.4e-10	33.7	COG1917	Cupin domain protein related to quercetin dioxygenase	131
2918281450	418	93.92	30	416	16	386	1.4e-27	90.8	COG2814	Predicted arabinose efflux permease, MFS family	394
2918281451	602	97.36	4	565	7	559	1.0e-123	408.4	COG1165	2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase	566
2918281452	1148	64.1	652	1147	216	640	1.1e-97	321.9	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2918281455	76	70.73	1	74	8	65	1.1e-08	29.7	COG2331	Predicted nucleic acid-binding protein, contains Zn-ribbon domain	82
2918281456	512	99.42	1	512	1	512	0.0e+00	645.1	COG3283	Transcriptional regulator of aromatic amino acids metabolism	511
2918281457	437	96.91	1	424	5	380	1.7e-85	282.1	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918281458	227	97.18	14	227	4	210	3.7e-65	214.1	COG1515	Deoxyinosine 3'endonuclease (endonuclease V)	212
2918281459	206	53.66	48	194	29	138	1.0e-25	85	COG1611	Predicted Rossmann fold nucleotide-binding protein	205
2918281460	227	47.73	134	193	8	49	6.4e-07	6.3	COG1873	Sporulation protein YlmC, PRC-barrel domain family	87
2918281460	227	69.32	42	103	7	67	6.4e-07	15.6	COG1873	Sporulation protein YlmC, PRC-barrel domain family	87
2918281461	190	97.45	6	183	3	193	7.8e-50	164	COG0693	Putative intracellular protease/amidase	188
2918281462	221	97.41	1	221	5	230	1.2e-80	264.8	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918281463	469	82.74	123	463	63	388	8.5e-59	194.4	COG0642	Signal transduction histidine kinase	336
2918281464	359	95.56	23	358	9	352	5.1e-61	200.3	COG0628	Predicted PurR-regulated permease PerM	355
2918281465	367	97.05	7	365	2	363	4.4e-69	227.8	COG4641	Spore maturation protein CgeB	373
2918281466	366	94.91	6	360	2	355	5.8e-78	257	COG4641	Spore maturation protein CgeB	373
2918281467	389	96.25	3	370	2	360	1.4e-60	199.7	COG4641	Spore maturation protein CgeB	373
2918281468	372	96.82	11	366	12	407	5.0e-28	93.4	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918281470	356	98.44	4	346	3	318	8.8e-77	253.1	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2918281471	372	98.44	1	354	3	318	2.6e-82	271.4	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2918281472	174	38.43	6	143	135	227	9.1e-08	26.9	COG2202	PAS domain	232
2918281473	435	80.94	3	428	80	423	7.3e-55	177.9	COG0840	Methyl-accepting chemotaxis protein	408
2918281474	70	91.3	1	65	1	63	5.2e-12	39.9	COG1942	Phenylpyruvate tautomerase PptA, 4-oxalocrotonate tautomerase family	69
2918281475	151	82.5	1	127	9	107	5.2e-30	98.1	COG1733	DNA-binding transcriptional regulator, HxlR family	120
2918281476	559	80.94	136	553	78	421	1.4e-54	177.4	COG0840	Methyl-accepting chemotaxis protein	408
2918281477	101	76.92	1	100	11	100	7.3e-13	43	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
2918281478	415	54.62	133	391	128	328	6.7e-24	78.9	COG2208	Serine phosphatase RsbU, regulator of sigma subunit	367
2918281479	301	89.47	3	189	7	125	9.5e-25	81.4	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918281480	1100	72.8	984	1095	13	103	2.9e-06	20.8	COG2198	HPt (histidine-containing phosphotransfer) domain	122
2918281480	1100	74.37	253	701	97	389	1.0e-79	263.6	COG0642	Signal transduction histidine kinase	336
2918281480	1100	91.73	711	840	6	127	8.5e-59	61.5	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918281480	1100	93.98	852	980	5	129	8.5e-59	126.8	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918281481	269	94.7	2	268	8	275	1.8e-41	136.7	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918281482	643	98.56	15	643	10	627	0.0e+00	858.8	COG3158	K+ transporter	627
2918281484	459	55.87	76	384	18	231	7.6e-07	19.1	COG1474	Cdc6-related protein, AAA superfamily ATPase	366
2918281486	230	98.1	4	214	3	209	5.3e-54	177.5	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918281487	246	98.1	23	223	1	207	2.3e-19	64.2	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918281488	213	98.1	1	213	1	207	6.1e-58	190.5	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918281489	187	64.97	7	130	7	108	9.4e-11	35.4	COG1225	Peroxiredoxin	157
2918281490	214	93.21	1	212	3	208	7.9e-45	147.6	COG4649	Uncharacterized protein	221
2918281491	453	28.54	336	453	68	180	2.3e-48	39.1	COG1520	Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat	370
2918281491	453	61.11	96	349	56	297	2.3e-48	120.2	COG1520	Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat	370
2918281492	463	99.1	1	462	4	444	0.0e+00	560.2	COG1160	Predicted GTPases	444
2918281493	440	21.94	254	338	104	146	6.9e-17	3.6	COG4961	Flp pilus assembly protein TadG	185
2918281493	440	35.2	7	120	7	75	6.9e-17	53.7	COG4961	Flp pilus assembly protein TadG	185
2918281494	152	48.28	8	53	5	32	1.8e-06	21.6	COG3847	Flp pilus assembly protein, pilin Flp	58
2918281495	129	53.57	1	128	14	118	7.7e-19	63	COG4961	Flp pilus assembly protein TadG	185
2918281496	235	83.96	2	234	2	226	1.1e-54	180.5	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918281497	482	97.02	12	477	2	457	0.0e+00	637.1	COG0034	Glutamine phosphoribosylpyrophosphate amidotransferase	470
2918281498	228	82.97	6	178	2	152	2.1e-27	90.7	COG1286	Uncharacterized membrane protein, required for colicin V production	182
2918281499	460	96.93	1	455	2	443	0.0e+00	611.4	COG1066	Predicted ATP-dependent serine protease	456
2918281500	278	98.39	14	267	4	308	2.0e-84	278	COG0024	Methionine aminopeptidase	255
2918281501	194	53.49	40	185	22	113	4.3e-14	47.1	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2918281502	304	92.54	21	301	21	293	1.7e-34	114.4	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918281503	69	86.96	1	67	6	65	9.9e-13	42.3	COG1942	Phenylpyruvate tautomerase PptA, 4-oxalocrotonate tautomerase family	69
2918281504	258	96.2	1	257	5	257	1.1e-98	324.2	COG1127	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, ATPase component MlaF	263
2918281505	258	95.13	1	258	12	265	3.0e-89	293.4	COG0767	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, permease component MlaE	267
2918281506	368	98.9	6	365	4	363	1.3e-112	370.9	COG0787	Alanine racemase	360
2918281507	509	99.54	30	501	1	434	0.0e+00	501.4	COG0305	Replicative DNA helicase	435
2918281508	406	97.55	99	379	8	286	2.0e-109	359.6	COG2230	Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases	283
2918281509	188	99.32	1	148	1	147	3.3e-50	164.4	COG0359	Ribosomal protein L9	148
2918281511	90	84.81	6	85	13	79	1.8e-31	103.2	COG0238	Ribosomal protein S18	75
2918281512	145	95.54	2	113	3	109	4.1e-35	114.6	COG0360	Ribosomal protein S6	112
2918281513	313	95.29	1	311	4	327	1.2e-80	265.6	COG0331	Malonyl CoA-acyl carrier protein transacylase	310
2918281514	245	99.25	2	244	2	267	1.9e-77	255	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918281515	79	95.06	1	78	3	79	4.2e-30	98.4	COG0236	Acyl carrier protein	80
2918281516	420	99.28	1	420	2	412	0.0e+00	539.2	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
2918281517	328	96.51	2	320	11	342	7.1e-95	312.2	COG1559	Cell division protein YceG, involved in septum cleavage	342
2918281519	664	97.69	361	657	2	297	2.6e-59	196.3	COG0741	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)	296
2918281520	291	97.66	1	291	4	295	1.0e-115	380.3	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
2918281521	158	94.12	5	158	7	150	1.5e-59	194.7	COG0691	tmRNA-binding protein	153
2918281522	342	87.42	50	341	35	298	6.7e-54	175.6	COG2813	16S rRNA G1207 methylase RsmC	300
2918281523	337	98.79	8	337	4	329	0.0e+00	472.5	COG0113	Delta-aminolevulinic acid dehydratase, porphobilinogen synthase	330
2918281524	300	85.06	2	266	1	336	2.1e-27	89.2	COG1409	3',5'-cyclic AMP phosphodiesterase CpdA	301
2918281525	306	98.68	1	303	3	300	3.4e-57	188.3	COG1597	Diacylglycerol kinase family enzyme	301
2918281526	359	98.11	8	330	6	265	2.6e-78	256.2	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918281527	157	94.74	10	144	3	128	1.4e-19	65	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918281528	425	94.27	1	420	6	416	8.5e-56	183.8	COG0025	NhaP-type Na+/H+ or K+/H+ antiporter	429
2918281529	251	99.21	2	248	3	254	1.3e-89	294.4	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2918281530	235	99.58	4	235	2	237	3.4e-87	286.1	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2918281531	409	97.54	11	398	7	363	8.2e-46	151.1	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918281532	295	97.67	9	295	4	297	5.0e-82	270.3	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2918281533	325	95.36	17	322	10	317	1.4e-82	272.1	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918281534	237	97.47	1	200	1	193	1.6e-43	143.3	COG0518	GMP synthase - Glutamine amidotransferase domain	198
2918281535	505	96.4	3	504	3	511	7.9e-111	365.8	COG0737	2',3'-cyclic-nucleotide 2'-phosphodiesterase/5'- or 3'-nucleotidase, 5'-nucleotidase family	517
2918281536	213	31.65	2	65	43	92	1.8e-07	3.5	COG5490	Uncharacterized protein	158
2918281536	213	93.67	59	212	7	154	1.8e-07	26.1	COG5490	Uncharacterized protein	158
2918281537	372	99.73	1	371	1	369	0.0e+00	559.5	COG0686	Alanine dehydrogenase	371
2918281538	532	97	335	532	2	195	2.4e-59	195.4	COG2068	CTP:molybdopterin cytidylyltransferase MocA	199
2918281539	237	47.18	6	237	144	285	4.7e-52	171.7	COG1975	Xanthine and CO dehydrogenase maturation factor, XdhC/CoxF family	278
2918281540	104	33.55	3	104	2	102	5.6e-32	105.9	COG1975	Xanthine and CO dehydrogenase maturation factor, XdhC/CoxF family	278
2918281541	402	97.48	1	388	8	394	7.3e-128	421.5	COG3552	Uncharacterized conserved protein, contains von Willebrand factor type A (vWA) domain	395
2918281542	307	77.58	3	301	21	276	3.9e-66	217.9	COG0714	MoxR-like ATPase	329
2918281543	264	98.25	1	264	1	281	1.5e-76	252.4	COG1319	CO or xanthine dehydrogenase, FAD-binding subunit	284
2918281544	797	99.46	2	788	4	744	0.0e+00	781.2	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
2918281545	165	96.79	3	157	3	153	2.9e-69	226.1	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
2918281546	312	96.27	2	312	10	319	3.7e-103	339.5	COG2358	TRAP-type uncharacterized transport system, periplasmic component	321
2918281547	698	96.19	5	693	18	648	0.0e+00	710.6	COG4666	TRAP-type uncharacterized transport system, fused permease components	642
2918281548	126	64.74	2	124	35	135	4.5e-17	56.8	COG4729	Uncharacterized protein	156
2918281549	483	99.29	42	483	3	423	6.0e-71	233.8	COG1055	Na+/H+ antiporter NhaD or related arsenite permease	424
2918281550	326	94.46	3	324	12	318	5.4e-94	309.5	COG0042	tRNA-dihydrouridine synthase	323
2918281551	153	90.07	14	152	6	132	5.0e-52	169.8	COG0229	Peptide methionine sulfoxide reductase MsrB	140
2918281552	329	97.96	12	328	3	338	6.7e-70	230.3	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2918281553	603	84.43	1	112	2	104	3.1e-76	118.5	COG1445	Phosphotransferase system fructose-specific component IIB	122
2918281553	603	85.25	122	243	4	107	3.1e-76	134.2	COG1445	Phosphotransferase system fructose-specific component IIB	122
2918281553	603	97.09	247	591	3	336	0.0e+00	455.3	COG1299	Phosphotransferase system, fructose-specific IIC component	343
2918281554	314	99.03	6	314	2	308	1.2e-93	308	COG1105	Fructose-1-phosphate kinase or kinase (PfkB)	310
2918281555	834	94.38	156	242	3	86	4.8e-23	74.4	COG1925	Phosphotransferase system, HPr and related phosphotransfer proteins	88
2918281555	834	97.89	2	143	2	140	1.2e-48	158.1	COG4668	Mannitol/fructose-specific phosphotransferase system, IIA domain	142
2918281555	834	98.78	268	830	2	568	0.0e+00	652.8	COG1080	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria)	574
2918281558	263	98.13	10	250	4	266	5.1e-50	165	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918281559	655	99.67	45	651	3	598	0.0e+00	750.3	COG0322	Excinuclease UvrABC, nuclease subunit	581
2918281560	200	92.78	1	186	11	190	1.6e-46	153.4	COG0558	Phosphatidylglycerophosphate synthase	192
2918281561	170	98.15	1	161	2	160	1.3e-43	143.5	COG1763	Molybdopterin-guanine dinucleotide biosynthesis protein	161
2918281562	417	98.53	10	417	5	405	0.0e+00	455.3	COG0303	Molybdopterin biosynthesis enzyme	404
2918281563	83	97.62	1	83	3	84	7.3e-24	79.1	COG1977	Molybdopterin converting factor, small subunit	84
2918281565	157	95.97	1	147	5	147	3.9e-51	167.4	COG0314	Molybdopterin synthase catalytic subunit	149
2918281566	240	73.76	44	178	30	133	3.0e-12	40.8	COG4642	Uncharacterized conserved protein	139
2918281567	210	99.52	1	209	1	207	3.4e-54	177.7	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
2918281568	381	20.68	40	254	99	147	1.6e-04	15.3	COG0412	Dienelactone hydrolase	236
2918281570	181	61.38	10	164	57	172	7.4e-13	43.2	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
2918281573	448	79.53	22	443	86	423	2.0e-62	206.4	COG0840	Methyl-accepting chemotaxis protein	408
2918281574	295	78.3	3	289	66	332	9.8e-88	289.3	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
2918281576	163	91.12	1	158	13	166	9.4e-51	166.7	COG1247	L-amino acid N-acyltransferase YncA	169
2918281577	136	87.16	2	136	11	139	8.8e-63	205.3	COG4957	Predicted transcriptional regulator	148
2918281578	91	95.74	1	91	2	91	1.5e-34	112.8	COG0776	Bacterial nucleoid DNA-binding protein	94
2918281580	361	86.53	1	354	13	346	1.9e-31	103.5	COG2327	Polysaccharide pyruvyl transferase family protein WcaK	385
2918281583	426	99.23	26	408	2	386	4.2e-84	277.5	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918281584	444	97.98	1	443	8	444	2.0e-128	423.4	COG0174	Glutamine synthetase	443
2918281587	366	96.03	1	366	13	375	3.3e-86	284.3	COG0687	Spermidine/putrescine-binding periplasmic protein	363
2918281588	383	98.58	19	383	3	350	0.0e+00	451.4	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
2918281589	307	94.79	6	307	12	284	7.9e-111	364.5	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
2918281590	283	95.51	1	268	12	266	1.8e-96	317	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
2918281591	339	97.69	1	338	8	345	3.0e-115	379.6	COG2957	Agmatine/peptidylarginine deiminase	346
2918281592	408	90.45	65	397	19	321	1.6e-17	58.8	COG0582	Integrase	309
2918281596	128	39.75	1	111	38	101	7.8e-04	14	COG5353	Uncharacterized protein YpmB	161
2918281597	297	98.67	2	296	1	297	6.0e-75	247.2	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918281598	550	97.48	6	543	2	542	1.5e-124	410.9	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
2918281601	475	48.83	253	464	8	194	4.7e-39	13.8	COG0477	MFS family permease	338
2918281601	475	76.76	3	292	8	301	4.7e-39	118.9	COG0477	MFS family permease	338
2918281602	268	98.11	9	265	6	265	1.6e-60	199.2	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918281603	553	96.19	1	552	20	575	3.1e-71	235.6	COG0747	ABC-type transport system, periplasmic component	556
2918281604	321	99.06	1	318	1	315	2.4e-114	376.7	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2918281605	283	90.27	1	282	28	296	6.5e-92	302.3	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2918281607	397	98.73	1	396	3	390	0.0e+00	452.8	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
2918281608	205	97.67	1	205	1	210	7.6e-43	141.5	COG0625	Glutathione S-transferase	211
2918281609	468	98.57	24	460	5	418	5.3e-125	412	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
2918281612	409	96.95	1	403	7	387	0.0e+00	521.8	COG3004	Na+/H+ antiporter NhaA	390
2918281614	363	99.64	45	363	1	280	6.7e-61	200.3	COG4395	Predicted lipid-binding transport protein, Tim44 family	281
2918281615	254	88.51	10	253	13	243	1.8e-64	211.8	COG4544	Uncharacterized conserved protein	260
2918281617	235	25.54	1	76	27	85	1.0e-21	32.2	COG3148	Uncharacterized conserved protein YfiP, DTW domain	231
2918281617	235	28.14	95	220	132	196	1.0e-21	38.7	COG3148	Uncharacterized conserved protein YfiP, DTW domain	231
2918281618	192	77.33	11	167	32	164	2.4e-26	86.7	COG5350	Predicted protein tyrosine phosphatase	172
2918281619	1048	92.65	1	1033	3	1074	0.0e+00	1016.9	COG0587	DNA polymerase III, alpha subunit	1139
2918281620	511	12.83	17	71	18	65	7.9e-41	8.9	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
2918281620	511	99.2	68	474	2	372	7.9e-41	125.3	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
2918281621	173	31	21	165	41	133	8.3e-01	4.1	COG3921	Uncharacterized conserved protein	300
2918281622	187	92.54	1	187	10	195	2.1e-21	70.6	COG2370	Hydrogenase/urease accessory protein HupE	201
2918281623	338	91.61	2	326	25	319	1.8e-78	258	COG2358	TRAP-type uncharacterized transport system, periplasmic component	321
2918281624	217	97.21	5	216	4	212	1.6e-39	130.6	COG0625	Glutathione S-transferase	211
2918281625	460	91.58	9	458	40	485	0.0e+00	441.9	COG0260	Leucyl aminopeptidase	485
2918281626	340	96.18	2	339	11	337	8.8e-100	328.8	COG1536	Flagellar motor switch protein FliG	339
2918281629	84	90.36	3	84	3	77	1.4e-15	51.8	COG3905	Predicted transcriptional regulator	83
2918281630	101	89.9	1	101	4	92	3.4e-12	41.6	COG3668	Plasmid stabilization system protein ParE	98
2918281631	148	60.15	4	140	17	96	1.0e-17	59	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918281632	312	86.5	12	312	45	326	5.6e-83	273	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
2918281633	212	70.33	1	191	65	237	6.4e-66	216.6	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
2918281635	546	99.06	7	537	5	533	0.0e+00	868.1	COG4172	ABC-type microcin C transport system, duplicated ATPase component YejF	534
2918281636	380	99.12	16	356	3	340	0.0e+00	592.7	COG4239	ABC-type microcin C transport system, permease component YejE	341
2918281637	371	99.73	1	370	1	363	0.0e+00	620.7	COG4174	ABC-type microcin C transport system, permease component YejB	364
2918281638	612	98.78	1	601	6	572	0.0e+00	513.3	COG4166	ABC-type oligopeptide transport system, periplasmic component	562
2918281639	613	97.74	1	613	7	567	0.0e+00	440.2	COG4166	ABC-type oligopeptide transport system, periplasmic component	562
2918281640	246	98.37	1	231	3	243	1.5e-67	222.1	COG0580	Glycerol uptake facilitator and related aquaporins (Major Intrinsic Protein Family)	241
2918281643	260	97.68	7	259	6	258	1.6e-65	215.6	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
2918281644	303	91.55	13	301	1	260	3.1e-75	248	COG2816	NADH pyrophosphatase NudC, Nudix superfamily	279
2918281645	494	93.96	1	492	11	539	0.0e+00	446	COG0659	Sulfate permease or related transporter, MFS superfamily	554
2918281646	288	98.21	3	279	3	277	3.5e-82	270.4	COG0077	Prephenate dehydratase	279
2918281647	242	97.17	1	242	6	245	7.6e-92	301.5	COG1212	CMP-2-keto-3-deoxyoctulosonic acid synthetase	247
2918281648	178	81.62	37	174	25	135	2.7e-43	141.7	COG3474	Cytochrome c2	135
2918281649	198	46.15	3	188	40	189	2.0e-11	37.9	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
2918281650	197	97.98	1	197	4	197	1.8e-73	240.7	COG0353	Recombinational DNA repair protein RecR	198
2918281651	107	97.14	1	104	4	105	5.6e-38	123.9	COG0718	Conserved DNA-binding protein YbaB (function unknown)	105
2918281652	615	62.74	21	585	2	368	0.0e+00	503.7	COG2812	DNA polymerase III, gamma/tau subunits	515
2918281654	269	78.03	134	263	21	123	1.5e-23	77.1	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918281655	401	53.79	203	398	3	208	9.9e-24	25.3	COG0477	MFS family permease	338
2918281655	401	70.5	5	258	8	277	9.9e-24	58.9	COG0477	MFS family permease	338
2918281656	829	71.83	240	684	108	390	1.4e-80	264.7	COG0642	Signal transduction histidine kinase	336
2918281657	397	98.49	1	397	4	395	0.0e+00	495.9	COG0126	3-phosphoglycerate kinase	395
2918281658	378	69.04	169	354	21	185	3.2e-23	76.3	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
2918281659	534	94.2	6	487	2	423	5.0e-74	244.1	COG3025	Inorganic triphosphatase YgiF, contains CYTH and CHAD domains	432
2918281660	207	25	1	74	2	67	5.3e-27	54.2	COG1192	Cellulose biosynthesis protein BcsQ	259
2918281660	207	47.35	72	206	127	251	5.3e-27	34.4	COG1192	Cellulose biosynthesis protein BcsQ	259
2918281661	254	98.83	1	254	1	254	7.8e-95	312	COG4106	Trans-aconitate methyltransferase	257
2918281663	461	89.59	10	461	34	386	3.2e-42	139.8	COG0642	Signal transduction histidine kinase	336
2918281664	456	99.34	2	432	4	455	9.6e-125	410.9	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
2918281665	233	90.62	5	232	10	212	7.3e-38	124.7	COG0398	Uncharacterized membrane protein YdjX, TVP38/TMEM64 family, SNARE-associated domain	223
2918281666	481	98.94	4	481	3	469	0.0e+00	581.3	COG2870	ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase	467
2918281667	52	95.45	3	46	3	44	1.2e-14	48.3	COG5510	Predicted small secreted protein	44
2918281668	292	98.31	6	292	3	292	4.5e-38	126.2	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918281669	466	99.78	2	456	2	455	0.0e+00	575.4	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
2918281670	319	98.67	13	315	5	300	2.0e-71	235.3	COG4974	Site-specific recombinase XerD	300
2918281671	227	98.62	2	224	2	216	2.5e-38	126.4	COG3159	Uncharacterized conserved protein YigA, DUF484 family	218
2918281672	218	97.04	1	218	8	302	9.6e-69	224.6	COG0176	Transaldolase	239
2918281673	741	99.59	20	740	4	734	0.0e+00	765.8	COG1198	Primosomal protein N' (replication factor Y) - superfamily II helicase	730
2918281676	189	97.75	7	183	5	178	3.5e-51	168.1	COG0712	FoF1-type ATP synthase, delta subunit	178
2918281677	509	99.21	1	509	1	500	0.0e+00	795.7	COG0056	FoF1-type ATP synthase, alpha subunit	504
2918281678	295	99.65	5	295	1	287	3.6e-104	343.1	COG0224	FoF1-type ATP synthase, gamma subunit	287
2918281679	479	99.36	9	477	3	467	0.0e+00	795.3	COG0055	FoF1-type ATP synthase, beta subunit	468
2918281680	139	97.78	1	135	1	132	5.8e-39	127.6	COG0355	FoF1-type ATP synthase, epsilon subunit	135
2918281681	275	85.96	14	174	21	173	1.4e-05	18.1	COG1633	Rubrerythrin	176
2918281682	164	86.63	3	156	11	159	8.0e-24	79	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2918281683	425	97.25	173	425	2	249	1.6e-64	211.8	COG2861	Uncharacterized conserved protein YibQ, putative polysaccharide deacetylase 2 family	250
2918281684	477	89.46	4	401	25	389	0.0e+00	439.6	COG0793	C-terminal processing protease CtpA/Prc, contains a PDZ domain	406
2918281685	496	50.47	285	489	208	422	8.1e-77	179	COG4942	Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB	420
2918281685	496	57.04	32	296	33	275	8.1e-77	82.7	COG4942	Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB	420
2918281686	521	99.21	5	513	4	508	0.0e+00	689.6	COG0696	Phosphoglycerate mutase (BPG-independent, AlkP superfamily)	509
2918281687	152	100	1	151	1	156	7.0e-47	154.1	COG1576	23S rRNA pseudoU1915 N3-methylase RlmH	155
2918281688	144	89.57	27	140	4	106	2.7e-38	124.8	COG0799	Ribosomal silencing factor RsfS, regulates association of 30S and 50S subunits	115
2918281689	205	86.93	14	205	4	176	2.9e-42	139.4	COG1057	Nicotinic acid mononucleotide adenylyltransferase	197
2918281690	426	99.04	11	426	4	416	0.0e+00	580.8	COG0014	Gamma-glutamyl phosphate reductase	417
2918281691	247	96.14	1	247	5	253	6.9e-42	138.2	COG0730	Uncharacterized membrane protein YfcA	258
2918281692	366	82.21	38	329	8	275	4.6e-10	33.9	COG2203	GAF domain	175
2918281693	227	96.83	10	225	2	215	1.9e-46	153.2	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
2918281694	386	98.65	13	386	5	369	0.0e+00	462	COG0263	Glutamate 5-kinase	369
2918281695	387	92.84	1	349	1	337	0.0e+00	450.6	COG0536	GTPase involved in cell partioning and DNA repair	369
2918281696	94	97.7	1	87	1	85	1.9e-44	144.1	COG0211	Ribosomal protein L27	87
2918281697	108	99.03	4	106	1	102	1.4e-43	142.3	COG0261	Ribosomal protein L21	103
2918281699	280	70.75	17	274	66	290	2.4e-25	81.6	COG0657	Acetyl esterase/lipase	312
2918281700	233	99.16	1	233	3	237	3.8e-83	272.9	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2918281701	251	98.82	1	246	3	253	1.2e-88	291.2	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2918281702	331	95.98	3	331	8	317	3.3e-78	257.7	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918281704	231	98.2	2	230	3	220	6.0e-83	272.1	COG0603	7-cyano-7-deazaguanine synthase (queuosine biosynthesis)	222
2918281706	304	96.68	2	304	5	295	2.1e-73	242.1	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2918281707	388	96.17	14	374	3	354	2.5e-53	175.9	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918281708	388	96.99	9	372	5	359	2.8e-50	165.8	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918281710	669	87.53	181	663	52	423	2.7e-64	212.8	COG0840	Methyl-accepting chemotaxis protein	408
2918281711	374	93.04	37	347	4	337	4.8e-41	136.4	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
2918281713	391	84.9	4	387	36	378	6.6e-57	188	COG1680	CubicO group peptidase, beta-lactamase class C family	390
2918281714	138	93.43	1	124	7	134	2.8e-06	21.2	COG4319	Ketosteroid isomerase homolog	137
2918281716	513	71.03	423	512	12	87	3.1e-09	30.3	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
2918281716	513	96.39	27	401	4	377	1.0e-48	160.9	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918281717	554	87.05	3	249	3	244	1.5e-58	192.1	COG0388	Predicted amidohydrolase	274
2918281717	554	97.81	262	543	3	270	1.2e-79	261.9	COG0171	NH3-dependent NAD+ synthetase	268
2918281719	189	88.2	1	178	4	160	3.5e-08	27.6	COG5405	ATP-dependent protease HslVU (ClpYQ), peptidase subunit	178
2918281720	222	98.62	5	222	3	216	1.7e-91	300.2	COG3155	Enhancing lycopene biosynthesis protein 2	217
2918281721	545	97.67	1	541	6	550	4.4e-88	290.8	COG3961	TPP-dependent 2-oxoacid decarboxylase, includes indolepyruvate decarboxylase	557
2918281724	142	100	1	142	1	144	7.9e-43	140.4	COG5458	Uncharacterized protein	144
2918281726	304	95.35	1	294	7	293	8.1e-45	148	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918281727	265	95.51	1	265	2	256	8.8e-52	170.8	COG0289	Dihydrodipicolinate reductase	266
2918281729	282	98.63	6	280	3	291	7.1e-50	164.5	COG1408	Predicted phosphohydrolase, MPP superfamily	284
2918281730	200	96.55	1	198	6	201	2.9e-60	198.1	COG3917	2-hydroxychromene-2-carboxylate isomerase	203
2918281731	237	99.14	1	234	1	230	6.2e-79	259.2	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918281733	144	95.59	19	144	4	133	1.2e-25	84.6	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
2918281734	702	65.68	115	579	149	437	8.4e-11	35.2	COG5316	Uncharacterized protein	421
2918281735	206	96.15	1	205	6	205	1.6e-52	172.7	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
2918281737	147	92.2	6	146	7	136	4.8e-31	101.9	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
2918281738	261	97.71	1	261	4	259	3.6e-110	361.9	COG2022	Thiamin biosynthesis thiazole synthase ThiGH, ThiG subunit	262
2918281739	69	97.06	1	69	3	68	1.4e-19	64.8	COG2104	Sulfur carrier protein ThiS (thiamine biosynthesis)	68
2918281740	393	98.2	13	392	5	385	3.6e-72	238.3	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918281742	485	97.14	42	485	10	450	0.0e+00	506.5	COG2239	Mg/Co/Ni transporter MgtE (contains CBS domain)	451
2918281743	100	74.36	1	100	15	101	1.0e-12	42.6	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
2918281745	221	91.56	1	221	10	215	9.5e-81	265.1	COG0321	Lipoate-protein ligase B	221
2918281749	96	87.1	4	93	3	83	5.5e-25	82.4	COG1254	Acylphosphatase	92
2918281750	88	11.72	5	83	351	408	1.5e-03	12	COG3428	Uncharacterized membrane protein YdbT, contains bPH2 (bacterial pleckstrin homology) domain	494
2918281751	570	96.83	27	569	12	561	0.0e+00	432.2	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2918281752	229	93.9	41	203	4	157	6.9e-45	147	COG1871	Chemotaxis receptor (MCP) glutamine deamidase CheD	164
2918281753	352	83.42	1	348	35	371	7.0e-41	135.4	COG1680	CubicO group peptidase, beta-lactamase class C family	390
2918281754	139	90.97	3	139	3	133	3.4e-24	80	COG2703	Hemerythrin	144
2918281755	897	99.62	10	890	2	785	0.0e+00	792.6	COG0574	Phosphoenolpyruvate synthase/pyruvate phosphate dikinase	740
2918281757	695	99.57	1	695	3	690	0.0e+00	839.1	COG0751	Glycyl-tRNA synthetase, beta subunit	691
2918281758	295	94.3	10	295	5	285	0.0e+00	519.1	COG0752	Glycyl-tRNA synthetase, alpha subunit	298
2918281759	85	57.89	32	83	12	44	4.9e-05	17.9	COG0333	Ribosomal protein L32	57
2918281760	262	95.75	1	262	5	252	8.3e-45	147.7	COG0730	Uncharacterized membrane protein YfcA	258
2918281761	75	82.19	4	74	4	63	8.4e-14	45.9	COG1598	Predicted nuclease of the RNAse H fold, HicB family	73
2918281762	290	71.56	5	287	61	289	1.5e-66	219.6	COG0616	Periplasmic serine protease, ClpP class	317
2918281763	568	91.29	117	562	36	423	5.4e-62	205.2	COG0840	Methyl-accepting chemotaxis protein	408
2918281764	243	95.16	1	242	10	245	3.9e-58	191.1	COG4123	tRNA1(Val) A37 N6-methylase TrmN6	248
2918281766	338	99.39	18	338	2	327	1.1e-101	334.8	COG0142	Geranylgeranyl pyrophosphate synthase	322
2918281770	129	22.04	83	126	145	185	2.2e-16	25.2	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
2918281770	129	32.26	10	92	39	98	2.2e-16	33	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
2918281771	263	90.2	43	236	15	198	8.7e-23	75.1	COG3381	Cytoplasmic chaperone TorD involved in molybdoenzyme TorA maturation	204
2918281772	334	54.84	15	181	37	104	8.2e-21	27.7	COG1145	Ferredoxin	99
2918281772	334	63.71	218	313	30	108	8.2e-21	44.6	COG1145	Ferredoxin	99
2918281773	713	66.75	186	578	127	389	1.7e-59	197.1	COG0642	Signal transduction histidine kinase	336
2918281773	713	96.99	588	713	3	131	2.4e-20	66.3	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918281776	302	99.3	19	301	2	285	1.9e-107	353.3	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
2918281777	316	91.41	189	314	4	120	1.2e-40	132.6	COG3603	Uncharacterized protein	128
2918281778	1208	98.86	5	1166	10	1136	0.0e+00	1303	COG1197	Transcription-repair coupling factor (superfamily II helicase)	1139
2918281779	95	89.36	1	93	6	89	9.0e-29	93.9	COG2938	Succinate dehydrogenase flavin-adding protein, antitoxin component of the CptAB toxin-antitoxin module	94
2918281780	555	69.04	47	409	121	392	2.3e-63	209.3	COG0642	Signal transduction histidine kinase	336
2918281780	555	91.73	419	547	6	127	4.3e-18	58.1	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918281781	466	97.87	17	466	9	467	2.5e-126	416.8	COG0277	FAD/FMN-containing dehydrogenase	459
2918281784	1211	92.39	702	1211	2	523	0.0e+00	701.8	COG0146	N-methylhydantoinase B/oxoprolinase/acetone carboxylase, alpha subunit	563
2918281784	1211	99.71	16	690	2	678	0.0e+00	793.8	COG0145	N-methylhydantoinase A/oxoprolinase/acetone carboxylase, beta subunit	674
2918281785	186	33.69	17	147	95	157	2.6e-06	22.2	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
2918281786	246	98.85	66	240	1	172	8.2e-32	105.3	COG1076	DnaJ-domain-containing proteins 1	174
2918281787	608	98.69	5	505	4	531	0.0e+00	497	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
2918281788	292	96.68	1	288	7	297	1.1e-42	141	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918281789	228	89.27	2	225	27	259	1.3e-73	242	COG3023	N-acetyl-anhydromuramyl-L-alanine amidase AmpD	257
2918281790	194	95	1	187	8	197	3.2e-26	86.4	COG4636	Endonuclease, Uma2 family (restriction endonuclease fold)	200
2918281791	420	50.65	204	416	8	201	3.6e-17	36.6	COG0477	MFS family permease	338
2918281791	420	51.7	11	210	5	202	3.6e-17	27.6	COG0477	MFS family permease	338
2918281793	165	91.1	3	152	1	133	1.1e-28	94.4	COG2001	MraZ, DNA-binding transcriptional regulator and inhibitor of RsmH methyltransferase activity	146
2918281794	324	98.41	1	313	4	313	3.4e-117	386.2	COG0275	16S rRNA C1402 N4-methylase RsmH	314
2918281796	598	32.28	19	209	19	222	4.9e-107	73.9	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
2918281796	598	61.39	188	553	241	628	4.9e-107	280.9	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
2918281797	485	97.52	4	483	11	482	0.0e+00	471.1	COG0769	UDP-N-acetylmuramyl tripeptide synthase	475
2918281798	486	99.12	5	463	2	451	0.0e+00	443.1	COG0770	UDP-N-acetylmuramyl pentapeptide synthase	451
2918281799	361	98.77	20	361	2	323	2.1e-109	360.1	COG0472	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase	319
2918281800	463	98.22	5	459	8	449	0.0e+00	440	COG0771	UDP-N-acetylmuramoylalanine-D-glutamate ligase	448
2918281801	373	96.07	7	372	7	373	5.2e-94	309.5	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
2918281802	386	99.16	9	370	1	355	4.2e-99	326.7	COG0707	UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase	357
2918281804	472	98.05	3	466	8	459	0.0e+00	556	COG0773	UDP-N-acetylmuramate-alanine ligase	459
2918281805	307	97.96	21	306	3	290	8.1e-95	311.5	COG0812	UDP-N-acetylenolpyruvoylglucosamine reductase	291
2918281806	309	99.37	3	305	2	317	5.0e-93	306.2	COG1181	D-alanine-D-alanine ligase and related ATP-grasp enzymes	317
2918281807	314	82.66	25	304	34	257	2.1e-43	142.8	COG1589	Cell division septal protein FtsQ	269
2918281808	400	85.25	1	385	10	379	1.0e-120	398	COG0849	Cell division ATPase FtsA	418
2918281809	583	90.52	5	350	10	324	0.0e+00	455.8	COG0206	Cell division GTPase FtsZ	338
2918281810	312	93.69	10	301	2	283	4.2e-119	391.6	COG0774	UDP-3-O-acyl-N-acetylglucosamine deacetylase	300
2918281814	138	87.5	2	133	3	128	2.6e-31	103	COG2703	Hemerythrin	144
2918281815	795	24.33	618	794	510	673	0.0e+00	152.5	COG0272	NAD-dependent DNA ligase	667
2918281815	795	86.2	18	624	4	584	0.0e+00	767.7	COG0272	NAD-dependent DNA ligase	667
2918281816	105	8.43	4	104	369	448	2.0e-04	14.2	COG0419	DNA repair exonuclease SbcCD ATPase subunit	908
2918281820	569	99.1	15	568	2	554	0.0e+00	600.1	COG0497	DNA repair ATPase RecN	557
2918281821	275	96.46	6	259	6	250	4.4e-90	296.1	COG4105	Outer membrane protein assembly factor BamD, BamD/ComL family	254
2918281822	235	80.18	37	235	38	211	3.6e-09	28	COG3143	Chemotaxis regulator CheZ, phosphatase of CheY~P	217
2918281824	403	30.88	50	144	22	88	2.3e-12	6.5	COG3143	Chemotaxis regulator CheZ, phosphatase of CheY~P	217
2918281824	403	37.79	143	237	129	210	2.3e-12	35.1	COG3143	Chemotaxis regulator CheZ, phosphatase of CheY~P	217
2918281825	121	50.86	1	121	1	118	5.6e-29	95.7	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918281826	672	34.1	74	218	10	142	4.4e-91	8.7	COG0006	Xaa-Pro aminopeptidase	384
2918281826	672	97.18	237	628	8	386	4.4e-91	289.6	COG0006	Xaa-Pro aminopeptidase	384
2918281827	155	95.27	1	143	5	145	1.9e-25	84.2	COG4103	Uncharacterized conserved protein, tellurite resistance protein B (TerB) family	148
2918281828	300	75.33	16	297	75	303	1.1e-54	180.7	COG2264	Ribosomal protein L11 methylase PrmA	300
2918281831	779	98.81	39	675	2	664	0.0e+00	774.8	COG0210	Superfamily I DNA or RNA helicase	655
2918281832	226	98.58	1	213	2	209	6.2e-55	180.7	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918281833	238	96.68	13	237	2	205	2.3e-54	178.7	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918281834	896	67.26	440	753	126	390	2.9e-63	209.5	COG0642	Signal transduction histidine kinase	336
2918281834	896	91.73	768	894	6	127	6.7e-21	67.6	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918281835	105	98.96	1	96	1	95	1.1e-43	142	COG0234	Co-chaperonin GroES (HSP10)	96
2918281836	542	98.55	1	538	1	542	0.0e+00	623.1	COG0459	Chaperonin GroEL (HSP60 family)	524
2918281837	264	15.59	159	255	215	260	3.5e-12	4.7	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918281837	264	53.22	21	220	18	174	3.5e-12	39.4	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918281839	106	29.63	1	91	99	162	1.1e-10	36.2	COG3316	Transposase (or an inactivated derivative)	215
2918281840	371	82.03	1	362	30	376	5.1e-60	198	COG3673	Uncharacterized protein, PA2063/DUF2235 family	423
2918281841	369	8.2	17	92	97	121	7.0e-16	8.8	COG2333	Metal-dependent hydrolase, beta-lactamase superfamily II	293
2918281841	369	29.51	192	330	178	267	7.0e-16	38.4	COG2333	Metal-dependent hydrolase, beta-lactamase superfamily II	293
2918281842	894	10.97	215	449	32	57	5.6e-03	9.4	COG1122	Energy-coupling factor transporter ATP-binding protein EcfA2	235
2918281845	644	50.44	102	629	155	440	1.6e-22	74.7	COG1404	Serine protease, subtilisin family	508
2918281848	107	23.86	2	105	208	291	5.3e-09	29.4	COG1566	Multidrug resistance efflux pump	352
2918281849	378	38.42	4	268	60	253	7.6e-14	45.7	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
2918281850	258	69.73	11	228	56	237	1.8e-12	40.8	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
2918281851	520	98.59	13	515	6	495	5.4e-97	320.3	COG1233	Phytoene dehydrogenase-related protein	487
2918281852	517	98.19	1	494	5	492	8.7e-106	349.4	COG1233	Phytoene dehydrogenase-related protein	487
2918281853	471	88.52	2	421	52	475	1.7e-82	271.6	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918281854	102	50.33	5	99	75	150	3.4e-23	76.7	COG4704	Uncharacterized conserved protein, DUF2141 family	151
2918281856	342	80.59	7	335	56	300	5.8e-21	69.3	COG2159	Predicted metal-dependent hydrolase, TIM-barrel fold	293
2918281858	391	48.83	195	391	8	194	5.3e-20	11.4	COG0477	MFS family permease	338
2918281858	391	74.41	1	232	8	292	5.3e-20	60	COG0477	MFS family permease	338
2918281859	137	87.5	2	136	4	129	3.1e-26	86.5	COG2703	Hemerythrin	144
2918281860	428	98.42	53	428	2	374	5.0e-104	342.7	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
2918281861	169	81.36	3	168	14	157	8.6e-10	31.9	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
2918281862	341	89.16	1	323	3	298	2.9e-51	169.2	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
2918281863	317	95.16	1	317	4	337	7.1e-52	171.5	COG0673	Predicted dehydrogenase	342
2918281865	432	93.36	5	285	2	268	3.7e-25	82.1	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
2918281866	407	29.57	6	98	1	89	5.4e-77	95.7	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918281866	407	97.01	109	406	5	296	5.4e-77	164.2	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918281867	223	97.64	3	216	3	209	7.6e-63	206.5	COG0684	Regulator of RNase E activity RraA	210
2918281868	352	97.62	1	352	5	373	0.0e+00	461.8	COG2828	2-Methylaconitate cis-trans-isomerase PrpF (2-methyl citrate pathway)	378
2918281869	289	97.5	15	289	5	277	3.0e-49	162.7	COG3618	Predicted metal-dependent hydrolase, TIM-barrel fold	279
2918281872	252	99.6	1	252	1	251	2.8e-117	385.4	COG4604	ABC-type enterochelin transport system, ATPase component	252
2918281873	300	94.3	1	300	18	315	5.3e-124	408.2	COG4605	ABC-type enterochelin transport system, permease component	316
2918281874	319	95.64	3	319	14	320	0.0e+00	434.1	COG4606	ABC-type enterochelin transport system, permease component	321
2918281875	318	87.81	29	315	39	319	1.0e-108	357.4	COG4607	ABC-type enterochelin transport system, periplasmic component	320
2918281876	145	97.86	6	145	3	139	9.1e-55	179.2	COG2510	Uncharacterized membrane protein	140
2918281877	489	92.65	169	489	12	326	2.4e-45	149.4	COG0547	Anthranilate phosphoribosyltransferase	338
2918281878	766	94.27	26	766	43	749	1.9e-120	397.6	COG4774	Outer membrane receptor for monomeric catechols	750
2918281879	228	98.69	1	228	4	229	7.5e-93	305	COG3128	Predicted 2-oxoglutarate- and Fe(II)-dependent dioxygenase YbiX	229
2918281880	226	8.76	167	219	117	145	1.8e-28	5.9	COG0790	TPR repeat	292
2918281880	226	19.94	3	96	201	266	1.8e-28	59.8	COG0790	TPR repeat	292
2918281880	226	23.87	82	169	93	171	1.8e-28	41.5	COG0790	TPR repeat	292
2918281881	361	96.4	10	361	3	350	1.2e-91	301.7	COG1304	FMN-dependent dehydrogenase, includes L-lactate dehydrogenase and type II isopentenyl diphosphate isomerase	360
2918281882	298	97.38	4	298	5	301	4.6e-81	266.7	COG2113	ABC-type proline/glycine betaine transport system, periplasmic component	302
2918281883	312	94.5	1	283	9	283	2.7e-116	382.5	COG4176	ABC-type proline/glycine betaine transport system, permease component	290
2918281884	398	99.23	1	398	2	386	0.0e+00	512.6	COG4175	ABC-type proline/glycine betaine transport system, ATPase component	386
2918281885	418	47	3	203	3	182	2.8e-20	35.6	COG0477	MFS family permease	338
2918281885	418	51.96	193	402	8	206	2.8e-20	37.3	COG0477	MFS family permease	338
2918281886	662	93.51	1	556	9	512	0.0e+00	652.7	COG1292	Choline-glycine betaine transporter	537
2918281887	176	22.22	81	168	37	64	9.7e-05	2.9	COG4854	Uncharacterized membrane protein	126
2918281887	176	58.73	4	91	45	118	9.7e-05	14.8	COG4854	Uncharacterized membrane protein	126
2918281889	199	76.61	3	107	4	98	1.1e-37	123.3	COG4288	Uncharacterized protein	124
2918281891	763	99.19	14	759	6	744	0.0e+00	622.2	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
2918281892	330	98.95	1	329	1	283	2.7e-103	340.2	COG1319	CO or xanthine dehydrogenase, FAD-binding subunit	284
2918281893	168	96.15	14	166	2	151	4.5e-70	228.9	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
2918281894	401	98.25	1	400	8	401	3.7e-64	211.5	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2918281895	250	99.25	3	249	2	267	7.7e-68	223.6	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918281896	320	98.34	1	300	1	296	8.6e-58	191	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918281897	577	19.05	2	83	81	156	7.6e-115	2.3	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918281897	577	97.49	177	577	7	395	7.6e-115	379	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918281898	886	99.24	2	871	7	922	0.0e+00	869.7	COG0567	2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes	906
2918281899	361	98.9	1	356	1	359	0.0e+00	517.7	COG4663	TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component	363
2918281900	215	96.7	10	191	1	176	2.1e-65	214.2	COG4665	TRAP-type mannitol/chloroaromatic compound transport system, small permease component	182
2918281901	650	98.88	50	623	4	445	0.0e+00	673.6	COG4664	TRAP-type mannitol/chloroaromatic compound transport system, large permease component	447
2918281902	327	98.06	1	326	1	303	1.1e-68	226.2	COG1893	Ketopantoate reductase	307
2918281903	484	98.33	8	484	3	473	0.0e+00	513.1	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918281904	488	99.36	20	484	3	468	9.3e-126	415	COG0277	FAD/FMN-containing dehydrogenase	459
2918281905	284	99.27	1	282	2	272	2.7e-85	280.6	COG3777	Hydroxyacyl-ACP dehydratase HTD2, hotdog domain	273
2918281906	292	98.95	13	288	1	282	3.7e-84	276.9	COG2301	Citrate lyase beta subunit	283
2918281907	138	41.76	1	110	1	109	1.1e-36	120.9	COG2086	Electron transfer flavoprotein, alpha and beta subunits	260
2918281908	282	96.51	5	264	3	251	2.2e-96	316.6	COG3638	ABC-type phosphate/phosphonate transport system, ATPase component	258
2918281909	332	94.35	1	294	9	292	5.4e-85	279.8	COG3221	ABC-type phosphate/phosphonate transport system, periplasmic component	299
2918281910	263	91.2	1	263	25	283	1.2e-95	314.8	COG3639	ABC-type phosphate/phosphonate transport system, permease component	283
2918281911	218	83.16	15	187	29	186	5.2e-37	122	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
2918281912	198	92.19	5	192	5	181	2.3e-59	194.7	COG3709	Ribose 1,5-bisphosphokinase PhnN	192
2918281913	381	99.73	5	381	2	377	0.0e+00	521.4	COG3454	Alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase PhnM	377
2918281914	227	96.17	1	227	1	226	2.5e-111	365.4	COG4778	Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL	235
2918281915	256	98.45	1	256	4	257	0.0e+00	477.2	COG4107	ABC-type phosphonate transport system, ATPase component	258
2918281916	284	95.88	1	284	8	286	0.0e+00	574.7	COG3627	Alpha-D-ribose 1-methylphosphonate 5-phosphate C-P lyase	291
2918281917	369	97.28	1	369	1	357	0.0e+00	631	COG3626	Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnI	367
2918281918	209	97.96	9	209	4	195	1.3e-71	234.8	COG3625	Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnH	196
2918281919	149	97.35	3	149	5	151	1.8e-58	191.3	COG3624	Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnG	151
2918281920	245	97.07	4	243	7	238	3.0e-64	211.3	COG2188	DNA-binding transcriptional regulator, GntR family	236
2918281921	385	99.47	3	379	2	376	4.0e-86	283.8	COG3454	Alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase PhnM	377
2918281922	234	19.23	47	145	37	71	6.3e-07	7.9	COG1514	2'-5' RNA ligase	180
2918281922	234	32.97	127	222	107	166	6.3e-07	14.2	COG1514	2'-5' RNA ligase	180
2918281924	157	32.47	48	157	12	111	2.4e-17	57.7	COG1073	Fermentation-respiration switch protein FrsA, has esterase activity, DUF1100 family	299
2918281925	399	97.47	10	398	7	391	1.8e-111	367	COG2814	Predicted arabinose efflux permease, MFS family	394
2918281926	349	99.12	1	346	2	339	3.7e-130	428.5	COG1064	D-arabinose 1-dehydrogenase, Zn-dependent alcohol dehydrogenase family	339
2918281927	265	70.97	32	140	34	121	4.8e-49	70.1	COG0599	Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family	124
2918281927	265	85.48	150	265	15	120	4.8e-49	88.4	COG0599	Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family	124
2918281928	298	97.01	5	298	3	294	1.1e-73	243.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918281930	98	21.67	7	97	5	87	3.2e-05	18.4	COG0477	MFS family permease	338
2918281931	131	92.37	1	125	10	130	1.6e-36	119.7	COG1917	Cupin domain protein related to quercetin dioxygenase	131
2918281933	131	67.18	21	116	10	97	1.2e-21	71.5	COG1917	Cupin domain protein related to quercetin dioxygenase	131
2918281935	311	98.34	5	299	3	298	1.2e-62	207	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918281936	249	99.63	1	248	1	267	2.2e-74	245.1	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918281937	281	97.53	4	246	7	243	9.2e-96	314.3	COG3959	Transketolase, N-terminal subunit	243
2918281938	331	97.12	19	331	9	311	8.5e-116	380.5	COG3958	Transketolase, C-terminal subunit	312
2918281939	326	96.39	1	326	11	330	9.7e-110	361.6	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
2918281940	186	92.09	16	186	8	170	2.3e-31	103.2	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
2918281941	419	97.89	46	419	2	372	3.3e-121	399.6	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
2918281942	295	99.3	2	286	2	285	5.1e-91	299.5	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
2918281943	319	97.86	3	319	3	322	2.9e-87	287.2	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
2918281944	662	98.79	6	662	6	660	0.0e+00	777.5	COG0021	Transketolase	663
2918281946	76	51.8	1	76	1	72	1.1e-11	39.4	COG3415	Transposase	138
2918281947	497	91	13	491	27	471	4.4e-89	289.7	COG1757	Na+/H+ antiporter NhaC	485
2918281948	312	99.36	1	303	1	310	1.9e-114	376.6	COG0549	Carbamate kinase	312
2918281949	334	99.04	2	333	3	310	1.4e-128	423.2	COG0078	Ornithine carbamoyltransferase	310
2918281950	409	99.02	1	408	4	406	0.0e+00	491.3	COG2235	Arginine deiminase	409
2918281951	501	93.29	14	496	7	465	4.5e-75	247.1	COG0531	Amino acid transporter	466
2918281952	190	86.96	1	190	16	195	4.2e-44	145.2	COG4245	Uncharacterized conserved protein YegL, contains vWA domain of TerY type	207
2918281959	434	47.46	173	430	157	315	8.0e-07	21.2	COG0582	Integrase	309
2918281960	239	29.5	42	87	4	44	1.2e-05	8.6	COG3415	Transposase	138
2918281960	239	76.98	96	196	7	113	1.2e-05	8.4	COG3415	Transposase	138
2918281962	288	55.07	214	272	5	42	7.4e-08	26	COG1476	DNA-binding transcriptional regulator, XRE-family HTH domain	68
2918281967	172	92	15	138	4	118	9.5e-23	75.4	COG3293	Transposase	124
2918281973	274	33.42	112	258	95	217	1.2e-13	30.3	COG0457	Tetratricopeptide (TPR) repeat	291
2918281973	274	38.04	1	155	165	304	1.2e-13	29.4	COG0457	Tetratricopeptide (TPR) repeat	291
2918281974	247	56.8	4	105	20	90	1.1e-09	23.7	COG3293	Transposase	124
2918281974	247	99.2	117	243	1	124	1.1e-09	10.5	COG3293	Transposase	124
2918281977	290	55.52	5	281	134	319	1.1e-14	49.3	COG0582	Integrase	309
2918281978	356	66.87	20	344	92	315	2.1e-20	66.8	COG0582	Integrase	309
2918281979	348	31.4	20	213	15	95	6.8e-09	29.6	COG2253	Predicted nucleotidyltransferase component of viral defense system	258
2918281983	189	78.37	1	189	54	245	1.3e-30	101.4	COG4923	Predicted nuclease (RNAse H fold)	245
2918281994	263	21.59	19	89	3	59	7.7e-23	50.6	COG1192	Cellulose biosynthesis protein BcsQ	259
2918281994	263	55.3	79	247	113	258	7.7e-23	24.3	COG1192	Cellulose biosynthesis protein BcsQ	259
2918281995	132	21.89	4	116	156	250	1.6e-03	12.3	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
2918281996	336	97.35	69	328	4	260	8.4e-53	174.3	COG1192	Cellulose biosynthesis protein BcsQ	259
2918281997	304	65.91	30	263	5	178	8.2e-38	125.3	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
2918282008	266	48.1	41	105	20	57	1.6e-03	11.9	COG1654	Biotin operon repressor	79
2918282017	67	36.24	6	63	91	144	1.0e-13	46	COG5642	Uncharacterized conserved protein, DUF2384 family	149
2918282022	389	89	80	381	17	283	6.4e-38	122.2	COG4974	Site-specific recombinase XerD	300
2918282023	92	23.47	20	92	38	102	1.1e-04	16.2	COG0338	Site-specific DNA-adenine methylase	274
2918282026	102	28.28	9	81	39	66	8.3e-04	14	COG3526	Predicted selenoprotein, Rdx family	99
2918282032	133	93.23	3	131	6	129	1.4e-10	35.4	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918282048	306	97.26	13	306	2	320	1.0e-45	143.9	COG1518	CRISPR/Cas system-associated endonuclease Cas1	327
2918282061	401	93.35	36	376	24	360	5.5e-36	118.9	COG3177	Fic family protein	348
2918282067	248	25	183	248	100	133	2.3e-11	7.1	COG4520	Surface antigen	136
2918282067	248	56.62	1	103	14	90	2.3e-11	31.4	COG4520	Surface antigen	136
2918282068	260	80	188	258	17	80	2.2e-24	79	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2918282069	441	8.75	295	345	401	449	3.0e-25	26.9	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918282069	441	14.29	338	436	417	496	3.0e-25	39	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918282069	441	35	6	310	265	460	3.0e-25	36.2	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918282070	306	96.01	15	303	7	295	8.0e-33	108.5	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918282071	207	58.46	85	197	2	77	5.1e-17	57.1	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918282073	180	43.07	19	172	93	179	2.0e-04	15.4	COG1573	Uracil-DNA glycosylase	202
2918282080	128	89.38	25	128	11	111	5.0e-30	98.2	COG2151	Metal-sulfur cluster biosynthetic enzyme	111
2918282082	401	96.72	5	400	14	396	1.2e-110	365.2	COG3213	Uncharacterized protein involved in response to NO	396
2918282083	241	98.17	9	222	2	215	1.4e-38	127.2	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2918282084	305	98.34	2	297	2	297	2.5e-53	176.4	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918282085	344	98.67	43	344	1	297	1.1e-34	114.8	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
2918282086	350	98.58	1	345	5	352	1.2e-121	401	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
2918282087	306	91.32	18	304	11	273	1.4e-72	239	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
2918282088	266	91.76	1	258	14	258	3.8e-78	257	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
2918282089	376	98.2	5	375	3	383	2.4e-56	186.2	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918282090	98	7.87	8	98	4	80	3.3e-04	13.3	COG3383	Predicted molibdopterin-dependent oxidoreductase YjgC	978
2918282091	469	9.53	1	55	146	186	1.1e-26	37	COG0446	NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase	415
2918282091	469	80.23	54	447	64	408	1.1e-26	56.3	COG0446	NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase	415
2918282092	380	97.94	6	379	5	384	1.5e-75	249.4	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918282093	115	90.44	2	115	11	133	1.6e-30	100.4	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
2918282094	254	95.05	1	254	5	273	2.8e-60	198.7	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918282095	115	85.29	2	115	19	134	1.1e-19	65.4	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
2918282096	253	77.99	1	126	4	127	1.0e-17	17.2	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2918282096	253	88.05	109	253	17	156	1.0e-17	42.9	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2918282097	268	27.46	131	239	211	291	3.3e-18	16.8	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918282097	268	37.29	7	163	22	131	3.3e-18	45.4	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918282099	158	94.07	1	141	6	132	4.5e-30	98.9	COG3791	Uncharacterized conserved protein	133
2918282100	99	68.22	2	98	24	111	2.0e-07	24.8	COG0662	Mannose-6-phosphate isomerase, cupin superfamily	127
2918282101	1736	92.84	203	1735	117	1632	0.0e+00	1159.3	COG2373	Uncharacterized conserved protein YfaS, alpha-2-macroglobulin family	1621
2918282102	678	9.67	580	678	662	732	0.0e+00	33.9	COG4953	Membrane carboxypeptidase/penicillin-binding protein PbpC	733
2918282102	678	75.2	3	601	13	564	0.0e+00	715.8	COG4953	Membrane carboxypeptidase/penicillin-binding protein PbpC	733
2918282103	1092	38.02	802	962	65	156	1.9e-66	13.1	COG2202	PAS domain	232
2918282103	1092	57.85	718	850	103	242	1.9e-66	53	COG2202	PAS domain	232
2918282103	1092	58.26	465	601	102	242	1.9e-66	58.7	COG2202	PAS domain	232
2918282103	1092	75.62	242	475	59	241	1.9e-66	63.5	COG2202	PAS domain	232
2918282103	1092	76.86	540	727	57	242	1.9e-66	84.9	COG2202	PAS domain	232
2918282104	556	78.68	213	552	82	391	1.2e-46	155	COG0642	Signal transduction histidine kinase	336
2918282105	147	87.97	4	141	3	119	7.2e-29	95	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918282106	453	31.26	3	160	133	268	1.5e-76	61	COG3706	Two-component response regulator, PleD family, consists of two REC domains and a diguanylate cyclase (GGDEF) domain	435
2918282106	453	39.31	218	439	262	432	1.5e-76	189.7	COG3706	Two-component response regulator, PleD family, consists of two REC domains and a diguanylate cyclase (GGDEF) domain	435
2918282107	362	56.85	3	267	62	285	4.3e-31	103.5	COG0642	Signal transduction histidine kinase	336
2918282108	292	64	187	283	14	93	3.8e-06	21.4	COG2198	HPt (histidine-containing phosphotransfer) domain	122
2918282108	292	93.98	44	169	6	130	8.0e-41	132.8	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918282109	824	84.71	283	711	53	412	1.1e-54	176.9	COG0840	Methyl-accepting chemotaxis protein	408
2918282110	125	60	10	121	14	88	3.5e-07	25.1	COG2198	HPt (histidine-containing phosphotransfer) domain	122
2918282111	213	96.68	1	210	1	204	3.8e-49	161.7	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918282113	114	89.38	8	113	2	102	3.7e-29	95.7	COG1320	Multisubunit Na+/H+ antiporter, MnhG subunit	113
2918282114	93	97.75	4	92	3	89	1.3e-30	100.3	COG2212	Multisubunit Na+/H+ antiporter, MnhF subunit	89
2918282115	162	100	4	162	1	158	1.2e-40	133.8	COG1863	Multisubunit Na+/H+ antiporter, MnhE subunit	158
2918282116	543	98.62	5	533	2	500	1.0e-122	404.9	COG0651	Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit	504
2918282117	114	98.25	1	114	1	112	1.5e-37	122.6	COG1006	Multisubunit Na+/H+ antiporter, MnhC subunit	115
2918282118	985	80.61	800	960	23	155	4.5e-58	66.7	COG2111	Multisubunit Na+/H+ antiporter, MnhB subunit	162
2918282118	985	89.47	7	645	2	553	0.0e+00	570.1	COG1009	NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit	606
2918282118	985	98.18	615	786	3	164	4.5e-58	138.9	COG2111	Multisubunit Na+/H+ antiporter, MnhB subunit	162
2918282119	162	92.76	2	149	8	148	2.6e-29	96.5	COG1762	Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type)	152
2918282121	288	94.97	139	282	5	155	5.6e-32	64.7	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2918282121	288	96.23	3	138	6	158	5.6e-32	47.1	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2918282122	542	76.9	134	539	90	392	1.9e-49	163.6	COG0642	Signal transduction histidine kinase	336
2918282123	206	97.52	2	203	4	200	1.8e-72	237.7	COG4566	Two-component response regulator, FixJ family, consists of REC and HTH domains	202
2918282124	157	82.88	18	156	13	133	1.9e-16	54.5	COG2172	Anti-sigma regulatory factor (Ser/Thr protein kinase)	146
2918282125	213	40.1	7	162	119	197	4.4e-23	76.9	COG2823	Osmotically-inducible protein OsmY, contains BON domain	196
2918282127	347	97.29	4	345	7	329	5.6e-79	260.4	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
2918282128	725	79.51	408	647	41	234	3.5e-45	149.1	COG2114	Adenylate cyclase, class 3	227
2918282129	192	60.49	15	186	19	116	1.7e-06	23.4	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2918282130	799	94.43	389	797	11	383	9.1e-12	39	COG2814	Predicted arabinose efflux permease, MFS family	394
2918282131	379	72.98	108	376	78	312	7.9e-11	35.5	COG2984	ABC-type uncharacterized transport system, periplasmic component	322
2918282132	387	98.35	7	373	5	362	7.5e-77	253.1	COG0787	Alanine racemase	360
2918282133	381	92.48	31	379	9	303	1.6e-49	163.7	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
2918282134	155	11.27	1	42	13	36	3.9e-13	6.1	COG0655	Multimeric flavodoxin WrbA	207
2918282134	155	32.39	44	127	74	142	3.9e-13	36.8	COG0655	Multimeric flavodoxin WrbA	207
2918282135	447	99.49	41	444	3	396	0.0e+00	538.2	COG0372	Citrate synthase	390
2918282136	113	89.42	1	99	8	100	6.5e-15	49.4	COG4274	Uncharacterized protein, contains GYD domain	104
2918282138	188	68.97	26	186	23	162	1.4e-34	113.3	COG3271	Predicted double-glycine peptidase	201
2918282141	288	95.21	1	288	13	310	8.8e-43	141.4	COG2017	Galactose mutarotase or related enzyme	308
2918282142	208	96.59	1	208	6	203	2.8e-58	191.3	COG2095	Small neutral amino acid transporter SnatA, MarC family	203
2918282143	126	55.45	3	124	2	118	1.1e-18	62.1	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918282144	210	73.27	1	196	6	153	2.8e-27	89.5	COG1776	Chemotaxis protein CheY-P-specific phosphatase CheC	203
2918282145	654	62.82	51	355	152	418	8.2e-82	140.7	COG0840	Methyl-accepting chemotaxis protein	408
2918282145	654	66.82	347	653	135	418	8.2e-82	130.4	COG0840	Methyl-accepting chemotaxis protein	408
2918282146	519	86.06	4	161	17	158	1.2e-91	83.2	COG0835	Chemotaxis signal transduction protein	165
2918282146	519	86.06	352	517	16	157	1.2e-91	111.9	COG0835	Chemotaxis signal transduction protein	165
2918282146	519	87.27	178	341	11	154	1.2e-91	100.9	COG0835	Chemotaxis signal transduction protein	165
2918282147	356	98.58	1	356	1	347	9.2e-104	341.9	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
2918282148	207	43.34	2	179	52	204	1.8e-16	53.3	COG1413	HEAT repeat	335
2918282149	278	98.89	7	278	2	268	2.6e-81	267.4	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
2918282150	133	89.47	1	128	5	123	1.0e-29	97.8	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918282151	730	97.48	1	730	7	741	0.0e+00	544.3	COG0643	Chemotaxis protein histidine kinase CheA	716
2918282153	579	20.38	2	75	192	266	9.6e-23	19.9	COG0457	Tetratricopeptide (TPR) repeat	291
2918282153	579	62.5	69	344	98	327	9.6e-23	58.4	COG0457	Tetratricopeptide (TPR) repeat	291
2918282154	132	50.43	1	121	1	117	2.1e-14	48	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918282155	623	48.76	2	133	120	237	4.1e-30	15.8	COG2202	PAS domain	232
2918282155	623	56.61	254	401	106	242	4.1e-30	21.9	COG2202	PAS domain	232
2918282155	623	58.68	98	256	100	241	4.1e-30	58.8	COG2202	PAS domain	232
2918282155	623	96.93	391	611	3	223	1.5e-51	168.6	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
2918282156	211	68.81	1	199	8	146	3.0e-27	90.2	COG1776	Chemotaxis protein CheY-P-specific phosphatase CheC	203
2918282157	376	94.98	1	376	20	416	8.2e-69	227.4	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
2918282158	629	67.01	82	478	127	390	4.3e-55	182.2	COG0642	Signal transduction histidine kinase	336
2918282158	629	89.47	504	628	7	125	4.8e-13	42.6	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918282159	115	27.62	5	101	58	123	1.1e-03	13	COG1579	Predicted  nucleic acid-binding protein, contains Zn-ribbon domain	239
2918282161	431	98.42	6	430	2	436	1.0e-90	296.8	COG1486	Alpha-galactosidase/6-phospho-beta-glucosidase, family 4 of glycosyl hydrolase	442
2918282162	441	98.27	3	441	3	457	0.0e+00	440.4	COG2723	Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase	460
2918282163	706	39.83	19	274	7	149	3.3e-20	67.9	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
2918282165	591	95.39	2	587	25	603	0.0e+00	497.1	COG4178	ABC-type uncharacterized transport system, permease and ATPase components	604
2918282166	450	97.41	10	449	4	454	0.0e+00	437	COG2723	Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase	460
2918282167	458	98.49	18	457	2	457	0.0e+00	452.8	COG2723	Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase	460
2918282168	157	94.59	4	150	6	145	1.7e-63	207.5	COG4957	Predicted transcriptional regulator	148
2918282169	432	72.76	194	420	64	258	8.8e-49	160.5	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
2918282171	352	90.29	2	352	34	405	2.0e-87	287.7	COG0334	Glutamate dehydrogenase/leucine dehydrogenase	411
2918282172	69	24.54	1	59	158	210	4.6e-12	40.7	COG3316	Transposase (or an inactivated derivative)	215
2918282173	119	54.42	1	115	1	123	1.8e-32	107.5	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
2918282174	596	33.12	12	151	46	147	1.5e-18	35.2	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
2918282174	596	37.66	255	517	34	149	1.5e-18	29.1	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
2918282175	837	87.49	80	826	81	814	1.2e-78	259.7	COG3250	Beta-galactosidase/beta-glucuronidase	808
2918282177	307	44.32	62	307	228	418	3.5e-18	60.1	COG0172	Seryl-tRNA synthetase	429
2918282178	382	92.23	1	375	18	385	4.8e-44	145.5	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918282179	104	75.31	18	101	16	76	1.5e-10	35.6	COG0236	Acyl carrier protein	80
2918282180	141	93.01	2	139	10	142	6.4e-35	114.9	COG1764	Organic hydroperoxide reductase OsmC/OhrA	143
2918282181	284	71.21	39	271	5	192	2.4e-36	120.5	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
2918282182	345	96.97	71	335	4	259	3.3e-56	185.5	COG1192	Cellulose biosynthesis protein BcsQ	259
2918282183	300	84.47	11	264	6	228	4.2e-31	103.4	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
2918282184	665	80.24	73	563	71	411	3.9e-58	191.1	COG0840	Methyl-accepting chemotaxis protein	408
2918282185	301	43.66	262	301	9	39	4.9e-04	6.7	COG3763	Uncharacterized protein YneF, UPF0154 family	71
2918282185	301	57.75	205	254	7	47	4.9e-04	4.9	COG3763	Uncharacterized protein YneF, UPF0154 family	71
2918282186	655	89.46	5	646	51	483	4.8e-83	274.4	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
2918282188	1065	79.58	9	496	6	457	2.4e-51	169.5	COG2303	Choline dehydrogenase or related flavoprotein	542
2918282188	1065	99.38	586	1065	1	481	3.0e-59	194.9	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
2918282189	315	96.55	1	314	10	317	1.5e-90	298.2	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918282190	354	81.9	33	336	51	317	4.5e-92	302.8	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
2918282191	686	99.27	4	685	5	682	0.0e+00	790.8	COG0339	Zn-dependent oligopeptidase	683
2918282195	285	86.36	36	282	2	229	1.9e-39	130.8	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
2918282196	341	96.97	76	337	4	259	5.5e-62	204.5	COG1192	Cellulose biosynthesis protein BcsQ	259
2918282198	211	67.78	1	169	13	174	7.7e-29	95	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
2918282199	420	96.39	1	417	14	440	5.9e-59	195.2	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
2918282200	295	96.31	3	292	6	292	4.4e-93	306.4	COG1175	ABC-type sugar transport system, permease component	295
2918282201	277	96.82	1	276	10	283	5.3e-81	266.8	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
2918282202	351	99.71	1	347	1	349	0.0e+00	458.6	COG3839	ABC-type sugar transport system, ATPase component	338
2918282205	1802	69.57	674	1355	60	315	1.3e-04	15.9	COG0457	Tetratricopeptide (TPR) repeat	291
2918282205	1802	77.92	1407	1802	82	388	2.3e-47	157.3	COG0642	Signal transduction histidine kinase	336
2918282206	316	94.72	1	316	16	320	7.0e-39	128.4	COG2984	ABC-type uncharacterized transport system, periplasmic component	322
2918282207	907	69.04	214	772	118	389	1.1e-75	241.9	COG0642	Signal transduction histidine kinase	336
2918282208	157	79.63	15	155	23	151	6.5e-12	40.7	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2918282212	251	85.05	1	251	40	295	1.8e-33	110.8	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918282213	139	56.49	15	127	45	118	1.3e-08	27.7	COG1917	Cupin domain protein related to quercetin dioxygenase	131
2918282214	510	96.59	1	510	3	512	0.0e+00	632.9	COG4670	Acyl CoA:acetate/3-ketoacid CoA transferase	527
2918282215	521	96.65	4	517	4	464	1.1e-48	160.5	COG4529	Uncharacterized NAD(P)/FAD-binding protein YdhS	474
2918282216	295	95.02	6	288	1	286	6.9e-52	171.6	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918282217	286	94.15	34	272	2	194	6.5e-59	193.1	COG1611	Predicted Rossmann fold nucleotide-binding protein	205
2918282219	263	97.64	2	253	4	251	2.3e-78	257.8	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
2918282220	222	94.94	8	222	9	233	1.2e-44	147.2	COG0412	Dienelactone hydrolase	236
2918282221	223	91.39	9	223	11	201	5.0e-26	87.3	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918282222	269	95.74	6	262	11	257	4.2e-77	253.7	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2918282223	336	91.94	1	327	9	316	1.4e-42	140.7	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918282224	275	97.61	21	274	2	246	1.4e-92	304.3	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2918282226	383	97.72	3	380	7	349	2.4e-59	196.1	COG0673	Predicted dehydrogenase	342
2918282228	292	95.32	16	287	14	278	3.3e-32	106.6	COG1082	Sugar phosphate isomerase/epimerase	274
2918282230	438	94.74	2	428	10	405	0.0e+00	438.2	COG1301	Na+/H+-dicarboxylate symporter	415
2918282231	651	98.34	16	618	10	603	0.0e+00	580.9	COG4191	Signal transduction histidine kinase regulating C4-dicarboxylate transport system	603
2918282232	451	97.43	11	451	6	460	0.0e+00	548.5	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2918282233	426	99.05	1	420	4	421	0.0e+00	570.9	COG2379	Glycerate-2-kinase	422
2918282234	297	96.68	4	297	3	293	1.1e-69	230.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918282235	129	92.37	1	123	10	130	1.3e-32	107.1	COG1917	Cupin domain protein related to quercetin dioxygenase	131
2918282236	354	98.83	1	345	4	340	8.5e-126	414.1	COG1064	D-arabinose 1-dehydrogenase, Zn-dependent alcohol dehydrogenase family	339
2918282237	391	97.59	43	388	3	367	4.4e-96	316.8	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
2918282238	195	14.35	123	181	133	162	1.5e-15	6.7	COG0406	Broad specificity phosphatase PhoE	208
2918282238	195	31.58	38	136	5	70	1.5e-15	44.9	COG0406	Broad specificity phosphatase PhoE	208
2918282239	419	94.28	1	409	17	428	4.6e-105	346.3	COG0612	Predicted Zn-dependent peptidase	438
2918282241	353	78.79	221	352	20	123	7.1e-29	94.1	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918282242	671	97.23	7	671	20	792	4.9e-44	143.9	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2918282243	96	13.58	1	69	38	81	1.0e-03	13.2	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
2918282244	103	97.92	1	95	1	94	4.8e-30	98.5	COG3553	Uncharacterized protein	96
2918282248	174	45.16	8	166	71	182	2.0e-46	153.6	COG0797	Rare lipoprotein A, peptidoglycan hydrolase digesting "naked" glycans, contains C-terminal SPOR domain	233
2918282249	370	16.3	7	113	36	57	5.2e-45	3.9	COG2863	Cytochrome c553	121
2918282249	370	66.67	273	369	28	117	5.2e-45	57.2	COG2863	Cytochrome c553	121
2918282249	370	69.63	144	285	41	134	5.2e-45	90.2	COG2863	Cytochrome c553	121
2918282250	333	87.8	13	252	10	232	2.6e-57	188.2	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
2918282251	843	77.93	649	823	29	194	7.0e-14	46.4	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
2918282251	843	92.27	27	581	10	534	0.0e+00	598.6	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
2918282252	119	21.9	1	116	183	274	2.5e-03	11.6	COG1668	ABC-type Na+ efflux pump, permease component	407
2918282253	624	95.44	8	585	4	568	0.0e+00	434.1	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
2918282259	349	57.11	1	247	6	230	4.7e-40	132.2	COG3621	Patatin-like phospholipase/acyl hydrolase	394
2918282261	140	95.65	1	139	4	135	1.1e-23	77.3	COG1558	Flagellar basal body rod protein FlgC	137
2918282262	274	93.38	3	273	6	259	1.7e-51	169.2	COG0631	Serine/threonine protein phosphatase PrpC	262
2918282263	525	34.26	11	374	3	163	4.1e-22	73.9	COG0515	Serine/threonine protein kinase	384
2918282265	173	88.51	35	173	4	134	1.4e-61	200.7	COG3260	Ni,Fe-hydrogenase III small subunit	148
2918282266	519	95.79	146	519	4	367	3.9e-99	326.2	COG3261	Ni,Fe-hydrogenase III large subunit	382
2918282267	477	92.69	2	476	7	475	1.4e-88	292.2	COG0651	Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit	504
2918282268	220	95.87	8	217	10	218	4.2e-26	86.6	COG4237	Hydrogenase-4 membrane subunit HyfE	218
2918282269	318	98.06	1	314	6	308	1.2e-71	236	COG0650	Formate hydrogenlyase subunit 4	309
2918282270	673	94.07	1	540	7	482	2.0e-117	387.3	COG0651	Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit	504
2918282273	792	98.72	1	790	9	780	0.0e+00	1070.4	COG2183	Transcriptional accessory protein Tex/SPT6	780
2918282274	369	59.5	5	201	99	242	1.5e-25	84.7	COG2202	PAS domain	232
2918282274	369	97.27	188	367	4	181	4.6e-56	183.7	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2918282275	211	97.12	2	208	5	206	6.7e-40	131	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
2918282280	211	46.92	11	130	11	71	3.2e-03	13.1	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918282281	146	90.98	13	140	3	123	1.0e-28	94.5	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918282283	232	51.35	5	144	4	98	1.4e-25	84.1	COG4461	Uncharacterized protein YPO0702	185
2918282284	106	97.22	1	106	1	105	8.3e-41	133.3	COG0393	Uncharacterized conserved protein YbjQ, UPF0145 family	108
2918282285	398	96.51	20	398	12	370	2.4e-90	297.8	COG2021	Homoserine acetyltransferase	368
2918282288	459	97.43	1	458	1	455	1.7e-92	305.2	COG4267	Uncharacterized membrane protein	467
2918282289	505	96.33	10	493	11	404	3.0e-37	123.5	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918282290	368	55.98	105	362	122	327	1.5e-04	16.6	COG0457	Tetratricopeptide (TPR) repeat	291
2918282292	197	70.39	31	193	19	125	4.5e-10	32.4	COG5616	TolB amino-terminal domain (function unknown)	152
2918282294	1018	14.23	402	564	335	403	2.1e-12	9.2	COG4783	Putative Zn-dependent protease, contains TPR repeats	484
2918282294	1018	14.64	30	122	357	427	2.1e-12	9.5	COG4783	Putative Zn-dependent protease, contains TPR repeats	484
2918282294	1018	14.64	943	1017	328	398	2.1e-12	21.4	COG4783	Putative Zn-dependent protease, contains TPR repeats	484
2918282294	1018	20	812	954	310	406	2.1e-12	15.7	COG4783	Putative Zn-dependent protease, contains TPR repeats	484
2918282294	1018	22.47	62	179	318	426	2.1e-12	9.4	COG4783	Putative Zn-dependent protease, contains TPR repeats	484
2918282296	293	74	36	292	65	286	2.3e-24	80.5	COG2342	Endo alpha-1,4 polygalactosaminidase, GH114 family (was erroneously annotated as Cys-tRNA synthetase)	300
2918282297	308	97.51	1	308	3	315	1.9e-82	272.1	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2918282298	136	91.73	6	134	6	127	1.9e-30	100	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918282299	119	87.22	2	119	8	123	4.6e-26	85.9	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918282300	607	98.61	1	599	3	568	0.0e+00	509.8	COG4166	ABC-type oligopeptide transport system, periplasmic component	562
2918282302	206	96.74	5	203	2	209	4.0e-45	148.9	COG0625	Glutathione S-transferase	211
2918282303	361	96.14	1	356	14	362	0.0e+00	504.3	COG4663	TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component	363
2918282304	544	97.87	11	512	3	508	1.1e-106	352.8	COG0366	Glycosidase	505
2918282306	373	95.79	4	364	12	352	1.5e-119	393.8	COG3569	DNA topoisomerase IB	354
2918282308	185	95.58	2	181	6	178	7.1e-57	186.5	COG3038	Cytochrome b561	181
2918282309	658	74.73	346	645	78	352	2.4e-37	123.1	COG2208	Serine phosphatase RsbU, regulator of sigma subunit	367
2918282309	658	77.56	10	200	25	145	3.6e-03	8.9	COG2165	Type II secretory pathway, pseudopilin PulG	149
2918282310	325	93.91	9	293	15	307	3.8e-44	145.4	COG0501	Zn-dependent protease with chaperone function	302
2918282311	311	33.51	159	309	219	347	3.3e-73	110.8	COG0484	DnaJ-class molecular chaperone with C-terminal Zn finger domain	371
2918282311	311	36.36	1	166	7	146	3.3e-73	130.2	COG0484	DnaJ-class molecular chaperone with C-terminal Zn finger domain	371
2918282313	63	35.24	1	58	29	65	1.1e-04	17.2	COG3027	Cell division protein ZapA, inhibits GTPase activity of FtsZ	105
2918282314	532	90.69	14	532	3	518	0.0e+00	770.5	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
2918282315	298	84.65	10	298	18	232	9.5e-70	229.1	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
2918282316	305	98.37	3	303	4	305	3.4e-64	211.4	COG0492	Thioredoxin reductase	305
2918282318	125	70.4	12	122	4	91	6.3e-11	37.4	COG2198	HPt (histidine-containing phosphotransfer) domain	122
2918282319	128	92.48	2	128	6	128	1.9e-30	100.2	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918282322	315	99.69	1	314	1	321	0.0e+00	503.1	COG0435	Glutathionyl-hydroquinone reductase	324
2918282323	200	98.12	1	200	3	211	1.4e-50	166.9	COG0655	Multimeric flavodoxin WrbA	207
2918282324	318	99	2	298	2	299	8.3e-87	286.4	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918282326	298	94.68	15	298	12	296	6.0e-43	141.9	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918282327	839	94.5	1	472	6	417	6.8e-67	220.1	COG0025	NhaP-type Na+/H+ or K+/H+ antiporter	429
2918282328	518	77.92	171	518	81	387	1.8e-43	144.5	COG0642	Signal transduction histidine kinase	336
2918282329	268	98.28	7	245	2	229	7.3e-46	150.9	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918282331	420	81.98	16	334	3	316	2.5e-15	49.2	COG0477	MFS family permease	338
2918282333	353	59.62	47	127	13	74	6.1e-03	4.6	COG4575	Membrane-anchored ribosome-binding protein, inhibits growth in stationary phase, ElaB/YqjD/DUF883 family	104
2918282333	353	65.38	100	183	30	97	6.1e-03	8.6	COG4575	Membrane-anchored ribosome-binding protein, inhibits growth in stationary phase, ElaB/YqjD/DUF883 family	104
2918282336	154	88.67	2	148	2	134	7.4e-35	114.8	COG1959	DNA-binding transcriptional regulator, IscR family	150
2918282337	495	99.54	40	493	2	433	0.0e+00	524.5	COG0719	Fe-S cluster assembly scaffold protein SufB	412
2918282338	97	94.74	1	96	3	92	5.8e-34	110.7	COG2827	Predicted endonuclease, GIY-YIG superfamily	95
2918282339	250	96.03	1	249	3	244	1.5e-105	346.5	COG0396	Fe-S cluster assembly ATPase SufC	251
2918282340	448	71.89	102	441	108	419	3.3e-72	238.1	COG0719	Fe-S cluster assembly scaffold protein SufB	412
2918282341	422	99.02	10	421	2	406	0.0e+00	516.3	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
2918282342	157	93.38	3	157	3	143	3.5e-43	141.8	COG0822	NifU homolog involved in Fe-S cluster formation	150
2918282343	133	85.84	24	133	10	106	3.7e-37	121.1	COG2151	Metal-sulfur cluster biosynthetic enzyme	111
2918282344	114	97.27	6	114	4	110	2.7e-39	128.2	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
2918282346	143	7.36	11	35	3	19	1.7e-11	6	COG1011	FMN phosphatase YigB, HAD superfamily	229
2918282346	143	42.86	30	139	98	196	1.7e-11	31.7	COG1011	FMN phosphatase YigB, HAD superfamily	229
2918282347	1006	16.43	291	430	369	460	3.1e-22	26.4	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918282347	1006	20.89	60	252	345	461	3.1e-22	36.8	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918282347	1006	44.29	468	879	264	511	3.1e-22	28.6	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918282348	467	91.03	25	458	34	388	1.7e-34	114.2	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918282349	720	98.59	4	716	10	710	0.0e+00	728.4	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
2918282352	236	61.9	4	236	4	237	3.3e-51	169	COG1208	NDP-sugar pyrophosphorylase, includes eIF-2Bgamma, eIF-2Bepsilon, and LPS biosynthesis proteins	358
2918282353	525	21.52	71	517	292	379	2.7e-06	21.9	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918282354	351	98.85	4	346	4	346	5.1e-122	401.7	COG2089	Sialic acid synthase SpsE, contains C-terminal SAF domain	347
2918282355	254	98.76	10	253	3	240	7.3e-68	222.8	COG1861	Spore coat polysaccharide biosynthesis protein SpsF, cytidylyltransferase family	241
2918282356	79	76.54	5	76	16	77	2.6e-08	28.6	COG0236	Acyl carrier protein	80
2918282357	271	98.64	5	268	4	294	3.1e-42	139.7	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918282358	83	85.19	2	79	6	74	3.2e-07	24.8	COG0236	Acyl carrier protein	80
2918282359	411	63.22	33	408	186	534	1.6e-32	106.5	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
2918282360	244	98.88	1	243	3	267	1.6e-61	202.7	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918282361	365	98.47	7	326	4	324	1.2e-79	262	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
2918282362	621	53.09	326	621	182	387	2.4e-26	33.5	COG1344	Flagellin and related hook-associated protein FlgL	360
2918282362	621	67.53	5	382	12	273	2.4e-26	55	COG1344	Flagellin and related hook-associated protein FlgL	360
2918282363	138	81.76	1	134	3	123	1.1e-23	78.1	COG5443	Flagellar biosynthesis regulator FlbT	148
2918282364	1976	46.2	956	1137	190	359	2.3e-92	53.7	COG0457	Tetratricopeptide (TPR) repeat	291
2918282364	1976	47.83	356	537	184	359	2.3e-92	40.9	COG0457	Tetratricopeptide (TPR) repeat	291
2918282364	1976	74.46	201	423	69	342	2.3e-92	76.8	COG0457	Tetratricopeptide (TPR) repeat	291
2918282364	1976	77.72	9	252	58	343	2.3e-92	70.6	COG0457	Tetratricopeptide (TPR) repeat	291
2918282364	1976	82.07	422	972	56	357	2.3e-92	63.2	COG0457	Tetratricopeptide (TPR) repeat	291
2918282364	1976	85.33	1381	1708	42	355	2.3e-92	71	COG0457	Tetratricopeptide (TPR) repeat	291
2918282365	60	92.98	1	57	1	53	4.2e-10	34.1	COG5570	Uncharacterized protein	57
2918282366	241	65.49	3	239	106	346	1.8e-15	51.9	COG0457	Tetratricopeptide (TPR) repeat	291
2918282367	1178	62.77	133	355	95	325	5.4e-62	80.3	COG0457	Tetratricopeptide (TPR) repeat	291
2918282367	1178	70.11	2	226	100	357	5.4e-62	80.5	COG0457	Tetratricopeptide (TPR) repeat	291
2918282367	1178	70.11	599	922	101	358	5.4e-62	66.9	COG0457	Tetratricopeptide (TPR) repeat	291
2918282368	413	33.8	23	132	4	100	2.1e-68	12.9	COG4976	Predicted methyltransferase, contains TPR repeat	287
2918282368	413	94.43	126	413	14	284	2.1e-68	217.1	COG4976	Predicted methyltransferase, contains TPR repeat	287
2918282369	304	81.79	3	277	58	358	3.3e-22	70.2	COG0457	Tetratricopeptide (TPR) repeat	291
2918282372	208	92	10	208	12	195	7.4e-65	213	COG0740	ATP-dependent protease ClpP, protease subunit	200
2918282373	283	41.23	4	262	5	152	1.1e-16	56.3	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
2918282374	265	73.42	1	250	1	290	1.5e-30	101.1	COG1409	3',5'-cyclic AMP phosphodiesterase CpdA	301
2918282376	377	96.41	1	371	8	383	7.0e-59	194.1	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918282377	1040	99.8	2	1018	2	1013	0.0e+00	1134.1	COG0841	Multidrug efflux pump subunit AcrB	1009
2918282378	433	98.42	52	433	5	377	3.8e-98	323.5	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
2918282379	169	87.57	1	168	5	159	1.3e-21	71.2	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
2918282380	332	96.08	5	332	9	327	9.4e-61	200.2	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
2918282381	398	93.59	1	377	13	377	1.0e-68	226.6	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918282382	1039	99.8	2	1014	1	1012	0.0e+00	1174.9	COG0841	Multidrug efflux pump subunit AcrB	1009
2918282383	303	98.34	3	303	1	296	1.1e-57	190.6	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918282384	249	97.3	4	249	5	256	1.8e-21	71	COG0730	Uncharacterized membrane protein YfcA	258
2918282385	1044	99.7	2	1021	2	1012	0.0e+00	1063.2	COG0841	Multidrug efflux pump subunit AcrB	1009
2918282386	385	95.9	10	384	5	378	6.7e-51	167.9	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918282387	220	93.3	7	215	3	197	4.0e-26	87.3	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918282390	193	82.7	5	193	31	183	7.7e-45	147.6	COG3108	Uncharacterized conserved protein YcbK, DUF882 family	185
2918282392	1111	26.9	206	372	66	171	8.8e-57	6.2	COG0642	Signal transduction histidine kinase	336
2918282392	1111	84.77	595	970	56	389	8.8e-57	188.1	COG0642	Signal transduction histidine kinase	336
2918282392	1111	90.98	986	1111	9	129	8.1e-17	53.4	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918282394	104	97.12	1	104	3	103	2.4e-36	118.2	COG1324	Uncharacterized protein involved in tolerance to divalent cations	104
2918282395	407	50.39	4	198	8	200	1.1e-26	60.5	COG0477	MFS family permease	338
2918282395	407	50.65	203	402	2	195	1.1e-26	34.1	COG0477	MFS family permease	338
2918282397	430	99.3	1	428	3	426	0.0e+00	626.5	COG2873	O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent	426
2918282398	172	95.71	8	147	4	137	1.4e-54	177.6	COG1832	Predicted CoA-binding protein	140
2918282399	268	98.87	9	265	4	265	1.9e-76	251.3	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918282400	746	66.5	208	733	127	388	1.4e-66	219.2	COG0642	Signal transduction histidine kinase	336
2918282401	156	94.33	3	142	7	139	2.5e-28	93	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
2918282402	154	96.62	1	149	1	143	1.0e-62	204.8	COG0102	Ribosomal protein L13	148
2918282403	162	96.99	31	162	5	133	5.3e-55	179.7	COG0103	Ribosomal protein S9	130
2918282404	350	99.43	6	350	3	349	4.3e-121	398.7	COG0002	N-acetyl-gamma-glutamylphosphate reductase	349
2918282405	172	93.22	3	172	5	169	9.5e-62	201.9	COG0663	Carbonic anhydrase or acetyltransferase, isoleucine patch superfamily	176
2918282406	197	53.77	19	191	88	194	6.5e-32	105.9	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
2918282407	599	99.56	140	596	2	451	0.0e+00	629.1	COG3243	Poly(3-hydroxyalkanoate) synthetase	445
2918282409	140	94.74	2	132	7	132	1.8e-27	90.5	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918282410	436	52.22	211	422	8	207	4.4e-29	9.8	COG0477	MFS family permease	338
2918282410	436	71.02	5	240	8	279	4.4e-29	89.8	COG0477	MFS family permease	338
2918282411	423	98.48	7	401	5	394	9.1e-128	421	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
2918282412	431	98.2	3	327	4	331	1.2e-112	370.7	COG0460	Homoserine dehydrogenase	333
2918282413	328	98.5	10	328	1	328	0.0e+00	451.1	COG1494	Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase or related protein	332
2918282414	602	96.03	55	574	9	492	0.0e+00	472.5	COG0608	Single-stranded DNA-specific exonuclease, DHH superfamily, may be involved in archaeal DNA replication intiation	491
2918282417	112	39.66	19	112	134	225	3.4e-09	30.7	COG3039	Transposase and inactivated derivatives, IS5 family	230
2918282418	166	38.96	4	135	3	129	2.6e-18	60.5	COG3547	Transposase	303
2918282419	242	59.67	27	214	95	273	1.3e-46	154.3	COG3921	Uncharacterized conserved protein	300
2918282420	355	34.74	18	190	43	116	5.9e-10	33.5	COG0655	Multimeric flavodoxin WrbA	207
2918282422	296	52.67	14	263	100	247	1.9e-35	117.3	COG3000	Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily	271
2918282424	163	88.48	1	149	14	159	1.0e-27	91.4	COG1656	Uncharacterized conserved protein, contains PIN domain	165
2918282425	473	99.79	1	470	2	478	0.0e+00	564.5	COG0469	Pyruvate kinase	477
2918282426	371	92.39	5	368	3	354	1.2e-84	278.9	COG0116	23S rRNA G2445 N2-methylase RlmL	381
2918282427	312	97.67	19	309	3	296	6.6e-69	227.3	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918282428	431	96.13	26	412	4	376	6.6e-67	220.8	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918282429	228	98.71	2	226	2	230	5.0e-73	239.6	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918282430	901	99.11	5	896	3	891	0.0e+00	1111.2	COG2205	K+-sensing histidine kinase KdpD	890
2918282431	193	99.47	1	189	1	188	3.0e-74	243.4	COG2156	K+-transporting ATPase, c chain	190
2918282432	700	98.97	4	700	7	681	0.0e+00	1056.5	COG2216	High-affinity K+ transport system, ATPase chain B	681
2918282433	568	99.29	2	562	4	559	0.0e+00	830.3	COG2060	K+-transporting ATPase, A chain	560
2918282434	211	85.95	3	175	25	183	4.8e-37	122.1	COG3108	Uncharacterized conserved protein YcbK, DUF882 family	185
2918282435	65	53.19	1	58	1	50	3.6e-17	57.2	COG1826	Sec-independent protein translocase protein TatA	94
2918282436	332	87.87	5	331	29	325	3.4e-77	253.8	COG1477	Thiamine biosynthesis lipoprotein ApbE	337
2918282437	193	97.73	2	181	2	173	6.4e-62	202.8	COG4314	Nitrous oxide reductase accessory protein NosL	176
2918282438	276	99.65	1	276	1	285	2.3e-47	156.5	COG1277	ABC-type transport system involved in multi-copper enzyme maturation, permease component	278
2918282439	289	78.1	4	284	4	242	3.8e-82	270.5	COG1131	ABC-type multidrug transport system, ATPase component	293
2918282440	458	98.28	8	451	5	405	0.0e+00	543	COG3420	Nitrous oxidase accessory protein NosD, contains tandem CASH domains	408
2918282441	648	99.84	1	645	1	636	0.0e+00	981.7	COG4263	Nitrous oxide reductase	637
2918282442	755	53.23	624	743	36	101	1.1e-03	11.5	COG1145	Ferredoxin	99
2918282442	755	96.89	5	487	15	481	0.0e+00	543.1	COG3901	Regulator of nitric oxide reductase transcription	482
2918282443	306	32.58	5	86	22	79	4.9e-20	29.9	COG1633	Rubrerythrin	176
2918282443	306	76.97	96	230	23	159	4.9e-20	35.5	COG1633	Rubrerythrin	176
2918282444	150	4.18	98	148	163	192	1.2e-05	3.7	COG3256	Nitric oxide reductase large subunit	717
2918282444	150	5.58	34	108	50	89	1.2e-05	13.6	COG3256	Nitric oxide reductase large subunit	717
2918282445	449	65.41	1	441	245	713	0.0e+00	499.9	COG3256	Nitric oxide reductase large subunit	717
2918282446	270	70.91	1	269	24	257	5.5e-48	158.2	COG0714	MoxR-like ATPase	329
2918282447	634	99.37	1	634	4	636	0.0e+00	583.2	COG4548	Nitric oxide reductase activation protein	637
2918282449	445	98.87	1	439	4	441	3.6e-66	218.8	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
2918282450	294	96.98	2	293	5	293	2.8e-82	270.8	COG1175	ABC-type sugar transport system, permease component	295
2918282451	288	95.76	2	288	9	279	8.1e-86	282.3	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
2918282452	356	99.43	1	349	1	348	0.0e+00	473.5	COG3839	ABC-type sugar transport system, ATPase component	338
2918282453	172	96.05	1	172	4	173	4.9e-64	209.5	COG0663	Carbonic anhydrase or acetyltransferase, isoleucine patch superfamily	176
2918282455	1153	99.83	1	1150	2	1167	0.0e+00	816.5	COG1196	Chromosome segregation ATPase	1163
2918282456	258	92.37	17	258	18	247	9.8e-41	134.3	COG1651	Protein-disulfide isomerase	244
2918282457	158	85.64	1	154	24	178	2.0e-31	103.9	COG5389	Uncharacterized protein	181
2918282458	161	94.89	11	141	4	133	3.6e-40	131.4	COG2764	Uncharacterized conserved protein PhnB, glyoxalase superfamily	136
2918282459	352	96.89	2	349	8	350	1.0e-118	391.1	COG1194	Adenine-specific DNA glycosylase, acts on AG and A-oxoG pairs	342
2918282461	798	76.4	398	781	90	390	2.7e-52	173.3	COG0642	Signal transduction histidine kinase	336
2918282462	127	95.04	21	127	4	118	1.5e-20	64	COG1539	Dihydroneopterin aldolase	121
2918282463	319	70.96	2	235	63	277	4.1e-70	230.6	COG0863	DNA modification methylase	302
2918282464	221	94.06	29	221	2	191	2.4e-62	205.2	COG0164	Ribonuclease HII	199
2918282465	244	50.46	3	120	26	135	8.4e-45	80.8	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2918282465	244	53.21	122	242	16	131	8.4e-45	65.7	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2918282466	161	97.35	1	159	4	150	8.4e-55	179.6	COG3012	Uncharacterized conserved protein YchJ, contains N- and C-terminal SEC-C domains	151
2918282467	195	95.52	20	86	2	65	3.6e-50	71.1	COG1278	Cold shock protein, CspA family	67
2918282467	195	95.52	129	195	3	66	3.6e-50	89.8	COG1278	Cold shock protein, CspA family	67
2918282468	475	82.35	26	427	42	377	1.8e-106	350.7	COG0793	C-terminal processing protease CtpA/Prc, contains a PDZ domain	406
2918282469	240	84	23	240	37	225	1.1e-72	238.4	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
2918282470	348	99.41	17	348	3	339	8.5e-117	383.9	COG0309	Hydrogenase maturation factor	339
2918282471	80	86.59	1	77	1	71	7.5e-25	81.3	COG0298	Hydrogenase maturation factor	82
2918282472	740	99.34	4	740	2	748	0.0e+00	783.6	COG0068	Hydrogenase maturation factor HypF (carbamoyltransferase)	750
2918282473	202	97.6	1	202	3	205	5.1e-46	151	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
2918282474	226	93.94	19	219	9	194	3.1e-65	212.9	COG0378	Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase	202
2918282475	119	25	4	97	66	129	2.6e-02	8.7	COG1989	Prepilin signal peptidase PulO (type II secretory pathway) or related peptidase	254
2918282476	113	98.26	1	113	1	113	2.0e-34	112.6	COG0375	Zn finger protein HypA/HybF (possibly regulating hydrogenase expression)	115
2918282477	390	21.59	1	123	12	109	3.4e-25	35.4	COG3259	Coenzyme F420-reducing hydrogenase, alpha subunit	441
2918282477	390	32.38	233	389	289	435	3.4e-25	46	COG3259	Coenzyme F420-reducing hydrogenase, alpha subunit	441
2918282478	227	81.82	10	61	5	49	1.4e-15	51	COG1773	Rubredoxin	55
2918282479	91	90.24	1	79	1	74	1.6e-13	44.9	COG0298	Hydrogenase maturation factor	82
2918282480	200	93.03	1	200	11	197	5.3e-54	177.1	COG2370	Hydrogenase/urease accessory protein HupE	201
2918282481	335	83.46	47	329	3	219	2.9e-35	116.3	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2918282482	557	81.41	150	552	78	423	4.9e-63	206.4	COG0840	Methyl-accepting chemotaxis protein	408
2918282483	159	98.12	1	157	2	158	3.5e-37	122.5	COG0680	Ni,Fe-hydrogenase maturation factor	160
2918282484	568	99.65	2	568	2	564	0.0e+00	712.3	COG0374	Ni,Fe-hydrogenase I large subunit	545
2918282485	396	95.51	7	393	6	388	6.4e-69	227.3	COG5557	Ni/Fe-hydrogenase 2 integral membrane subunit HybB	401
2918282486	349	77.07	42	284	11	168	7.1e-50	163	COG0437	Fe-S-cluster-containing dehydrogenase component	203
2918282487	398	92.68	30	392	11	339	2.2e-118	389.6	COG1740	Ni,Fe-hydrogenase I small subunit	355
2918282488	563	91.06	75	558	37	423	2.1e-61	197.1	COG0840	Methyl-accepting chemotaxis protein	408
2918282489	574	76.14	135	572	89	388	2.7e-77	254.4	COG0642	Signal transduction histidine kinase	336
2918282491	300	49.73	1	135	5	96	1.4e-16	54.7	COG4461	Uncharacterized protein YPO0702	185
2918282492	569	98.29	1	569	7	580	0.0e+00	697.7	COG1001	Adenine deaminase	584
2918282496	84	12.14	1	77	473	539	1.1e-14	48.2	COG4626	Phage terminase-like protein, large subunit, contains N-terminal HTH domain	546
2918282497	422	75.36	3	422	58	473	1.3e-72	239.2	COG4626	Phage terminase-like protein, large subunit, contains N-terminal HTH domain	546
2918282499	134	64.38	2	133	34	136	3.0e-22	73.7	COG3747	Phage terminase, small subunit	160
2918282500	153	49.03	5	117	45	120	5.1e-08	26.5	COG1403	5-methylcytosine-specific restriction endonuclease McrA	146
2918282502	404	89.57	12	404	43	420	3.6e-67	220.6	COG4653	Predicted phage phi-C31 gp36 major capsid-like protein	422
2918282503	178	84.54	1	170	9	172	2.3e-30	100	COG3740	Phage head maturation protease	194
2918282504	422	90.37	2	399	35	400	1.6e-59	195.9	COG4695	Phage portal protein BeeE	398
2918282509	184	52.27	2	102	1	69	1.8e-08	29	COG0789	DNA-binding transcriptional regulator, MerR family	124
2918282511	179	98.11	3	164	3	158	9.8e-63	205.1	COG0669	Phosphopantetheine adenylyltransferase	159
2918282512	937	99.26	4	893	6	812	0.0e+00	1131.6	COG0188	DNA gyrase/topoisomerase IV, subunit A	804
2918282513	451	93.91	5	451	17	448	1.3e-79	262.2	COG0534	Na+-driven multidrug efflux pump	455
2918282514	50	93.18	9	50	4	44	8.8e-18	58.3	COG5510	Predicted small secreted protein	44
2918282517	209	21.07	3	202	345	462	1.2e-15	50.7	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918282519	169	81.82	1	168	3	173	8.9e-36	114.8	COG0406	Broad specificity phosphatase PhoE	208
2918282520	231	96.85	9	227	5	219	1.5e-53	176.3	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
2918282521	372	98.02	14	372	4	349	1.4e-127	420.3	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
2918282522	570	97.24	13	566	11	539	2.7e-119	393.3	COG1178	ABC-type Fe3+ transport system, permease component	540
2918282523	448	85.71	45	349	3	260	1.9e-53	176.5	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
2918282524	447	98.29	1	447	6	464	0.0e+00	555.3	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2918282525	818	96.43	24	816	7	655	5.1e-82	262.8	COG4192	Signal transduction histidine kinase regulating phosphoglycerate transport system	673
2918282526	468	85.38	49	331	3	259	4.1e-42	138.7	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
2918282527	160	98.83	1	160	3	171	8.6e-24	79.3	COG0629	Single-stranded DNA-binding protein	167
2918282528	950	99.68	1	942	3	940	0.0e+00	1495.6	COG0178	Excinuclease UvrABC ATPase subunit	935
2918282529	68	10.16	2	63	2	46	1.3e-03	12.9	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
2918282530	158	92.36	14	158	7	151	3.4e-03	11.7	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
2918282531	452	98.86	4	450	4	437	0.0e+00	685.6	COG1206	Folate-dependent tRNA-U54 methylase TrmFO/GidA	439
2918282532	690	81.41	169	685	78	423	2.5e-67	222.1	COG0840	Methyl-accepting chemotaxis protein	408
2918282534	284	93.08	1	282	7	275	4.3e-46	152	COG1562	Phytoene/squalene synthetase	288
2918282535	290	88.93	20	286	20	276	3.4e-37	122.7	COG1562	Phytoene/squalene synthetase	288
2918282536	297	95.16	6	292	8	282	2.4e-63	208.5	COG1562	Phytoene/squalene synthetase	288
2918282537	446	15.9	220	356	239	317	8.9e-18	5.3	COG1233	Phytoene dehydrogenase-related protein	487
2918282537	446	19.52	18	204	8	104	8.9e-18	50.7	COG1233	Phytoene dehydrogenase-related protein	487
2918282538	183	89.27	1	183	20	202	5.5e-69	226.7	COG0605	Superoxide dismutase	204
2918282539	125	88.98	4	124	14	126	2.0e-38	126	COG3737	Uncharacterized conserved protein, contains Mth938-like domain	127
2918282540	314	97.08	4	309	3	301	3.4e-102	336	COG0341	Preprotein translocase subunit SecF	305
2918282541	532	98.66	1	532	1	516	0.0e+00	581.6	COG0342	Preprotein translocase subunit SecD	506
2918282542	142	91.75	12	109	5	93	2.5e-33	108.3	COG1862	Preprotein translocase subunit YajC	97
2918282543	286	96.89	1	286	7	286	4.0e-120	394.7	COG2607	Predicted ATPase, AAA+ superfamily	287
2918282544	436	14.87	39	89	3	49	3.3e-52	7.3	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
2918282544	436	95.57	87	430	3	304	3.3e-52	163.3	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
2918282545	210	92.42	1	205	10	204	3.1e-72	236.9	COG2518	Protein-L-isoaspartate O-methyltransferase	209
2918282546	260	98.05	11	260	2	252	1.9e-88	290.7	COG0496	Broad specificity polyphosphatase and 5'/3'-nucleotidase SurE	252
2918282547	423	99.07	1	423	1	427	0.0e+00	613.7	COG0172	Seryl-tRNA synthetase	429
2918282548	388	93.99	206	383	10	181	4.8e-53	173.9	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2918282549	271	97.68	12	271	3	255	1.5e-86	284.5	COG0805	Sec-independent protein secretion pathway component TatC	255
2918282550	164	85.11	1	92	1	80	1.9e-17	57.7	COG1826	Sec-independent protein translocase protein TatA	94
2918282551	86	69.15	1	86	1	65	1.4e-19	65	COG1826	Sec-independent protein translocase protein TatA	94
2918282552	419	88.95	61	415	5	318	1.9e-98	324.3	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
2918282553	209	94.02	10	187	8	180	3.9e-58	190.4	COG1386	Chromosome segregation and condensation protein ScpB	184
2918282554	259	96.37	17	259	3	241	4.5e-59	194.6	COG1354	Chromatin segregation and condensation protein Rec8/ScpA/Scc1, kleisin family	248
2918282555	228	88.14	1	225	13	220	3.8e-34	112.8	COG1994	Zn-dependent protease (includes SpoIVFB)	230
2918282556	347	73.62	7	330	6	312	7.9e-74	243.6	COG1472	Periplasmic beta-glucosidase and related glycosidases	397
2918282558	586	100	1	584	1	581	0.0e+00	532.7	COG0018	Arginyl-tRNA synthetase	577
2918282559	399	98.57	2	396	5	419	2.3e-119	393.9	COG0232	dGTP triphosphohydrolase	412
2918282560	132	95.45	24	132	5	109	3.6e-41	134	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
2918282561	257	99.23	1	256	2	258	1.3e-82	271.5	COG0708	Exonuclease III	261
2918282565	218	75.69	1	217	48	240	2.9e-43	142.3	COG1948	ERCC4-type nuclease	254
2918282575	447	99.39	55	224	1	162	1.0e-11	38.4	COG3436	Transposase	157
2918282577	100	54.6	1	100	39	127	1.1e-24	81.5	COG3436	Transposase	157
2918282580	349	99.42	4	349	2	346	3.3e-124	408.7	COG2089	Sialic acid synthase SpsE, contains C-terminal SAF domain	347
2918282581	230	89.84	1	230	11	231	1.0e-33	111.6	COG2120	N-acetylglucosaminyl deacetylase, LmbE family	237
2918282582	227	59.09	15	222	71	252	1.1e-17	58.6	COG0223	Methionyl-tRNA formyltransferase	307
2918282583	235	45.78	64	233	104	244	2.7e-15	50.7	COG0223	Methionyl-tRNA formyltransferase	307
2918282584	318	77.67	42	311	70	316	2.3e-50	165.8	COG3980	Spore coat polysaccharide biosynthesis protein SpsG, predicted glycosyltransferase	318
2918282585	401	98.13	6	399	4	371	1.8e-115	380.3	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
2918282586	354	57.4	8	354	250	594	4.3e-120	396.5	COG1086	NDP-sugar epimerase, includes UDP-GlcNAc-inverting 4,6-dehydratase FlaA1 and capsular polysaccharide biosynthesis protein EpsC	588
2918282587	389	59.9	21	388	160	404	2.4e-27	91.2	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918282591	158	47.1	11	142	57	129	6.2e-04	11.3	COG1403	5-methylcytosine-specific restriction endonuclease McrA	146
2918282595	505	99.01	7	505	1	499	0.0e+00	649.4	COG3333	TctA family transporter	504
2918282596	222	93.87	2	216	10	208	1.0e-67	222.3	COG0684	Regulator of RNase E activity RraA	210
2918282598	465	16.07	343	446	401	490	1.8e-36	55.1	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918282598	465	33.75	3	358	264	452	1.8e-36	79.5	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918282604	314	78.76	1	180	1	178	4.4e-49	161.2	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
2918282605	601	99.16	19	597	4	590	5.3e-126	416.1	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
2918282608	231	21.21	1	74	1	56	5.1e-27	48	COG1192	Cellulose biosynthesis protein BcsQ	259
2918282608	231	53.03	57	216	120	259	5.1e-27	40.7	COG1192	Cellulose biosynthesis protein BcsQ	259
2918282609	196	95.48	8	183	8	176	5.7e-62	203	COG0279	Phosphoheptose isomerase	176
2918282610	498	72.13	13	413	88	382	1.4e-16	55.4	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918282611	318	67.29	45	318	109	359	3.0e-05	14.4	COG4641	Spore maturation protein CgeB	373
2918282613	414	28.97	6	264	5	108	1.4e-13	46	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
2918282614	296	50	10	260	7	207	5.1e-34	112	COG3551	Uncharacterized protein	402
2918282615	457	96.02	5	249	3	243	5.2e-92	302.2	COG1134	ABC-type polysaccharide/polyol phosphate transport system, ATPase component	249
2918282618	283	87.69	1	283	34	268	8.5e-81	265.6	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
2918282619	636	97.93	22	457	1	425	0.0e+00	654.9	COG2895	Sulfate adenylyltransferase subunit 1, EFTu-like GTPase family	431
2918282619	636	97.97	442	636	2	194	3.9e-86	281.5	COG0529	Adenylylsulfate kinase or related kinase	197
2918282621	277	97.36	1	277	7	264	5.1e-57	187.4	COG1682	ABC-type polysaccharide/polyol phosphate export permease	263
2918282622	1061	30.54	875	1050	322	492	2.7e-41	78.1	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918282622	1061	58.04	128	473	231	555	2.7e-41	38.8	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918282622	1061	59.46	356	885	128	460	2.7e-41	12.3	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918282623	1019	14.29	909	1006	412	491	3.2e-17	42.2	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918282623	1019	68.75	19	916	70	454	3.2e-17	17.3	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918282624	271	98.49	11	271	5	265	2.2e-67	221.5	COG1682	ABC-type polysaccharide/polyol phosphate export permease	263
2918282625	267	97.61	1	254	3	247	6.4e-84	275.8	COG1134	ABC-type polysaccharide/polyol phosphate transport system, ATPase component	249
2918282626	457	33.7	117	390	4	124	4.9e-11	37.8	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
2918282627	366	96.33	1	355	13	406	9.7e-19	63	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918282628	433	96.33	1	430	9	428	1.2e-125	413.9	COG0677	UDP-N-acetyl-D-mannosaminuronate dehydrogenase	436
2918282629	250	43.73	5	245	5	161	1.4e-24	82.3	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
2918282630	718	98.17	3	711	13	710	0.0e+00	723.7	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
2918282631	466	93.08	13	457	26	388	1.2e-23	78.1	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918282632	445	22.66	11	139	117	191	5.1e-77	57.5	COG0790	TPR repeat	292
2918282632	445	33.53	345	442	203	313	5.1e-77	62.2	COG0790	TPR repeat	292
2918282632	445	77.34	130	363	54	309	5.1e-77	153.1	COG0790	TPR repeat	292
2918282633	863	11.07	236	310	402	463	9.9e-58	21.6	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918282633	863	11.07	304	374	402	463	9.9e-58	39.3	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918282633	863	17.32	540	678	364	460	9.9e-58	29.2	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918282633	863	20.54	382	513	423	537	9.9e-58	36.6	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918282633	863	32.5	664	851	310	491	9.9e-58	94.8	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918282634	223	98.71	1	223	1	229	1.4e-77	254.6	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918282635	475	82.74	93	469	64	389	1.2e-61	203.3	COG0642	Signal transduction histidine kinase	336
2918282636	371	84.97	9	309	5	281	4.5e-49	161.5	COG3547	Transposase	303
2918282637	278	68.66	109	204	25	116	9.0e-13	22.7	COG3335	Transposase	132
2918282637	278	91.79	45	168	12	134	9.0e-13	25.7	COG3335	Transposase	132
2918282639	69	24.54	1	59	158	210	1.0e-11	39.4	COG3316	Transposase (or an inactivated derivative)	215
2918282641	354	91.37	2	266	8	240	5.4e-39	128.4	COG1462	Curli biogenesis system outer membrane secretion channel CsgG	252
2918282646	110	36.94	7	109	65	105	1.2e-11	38.7	COG4226	Predicted nuclease of the RNAse H fold, HicB family	111
2918282647	169	85.82	37	166	3	117	1.9e-12	41.8	COG3335	Transposase	132
2918282651	140	98.48	4	136	2	131	8.1e-41	134	COG1487	Predicted nucleic acid-binding protein, contains PIN domain	133
2918282652	74	97.33	3	74	2	74	1.3e-21	70.7	COG4456	Virulence-associated protein VagC (function unknown)	74
2918282657	76	18.82	5	75	68	121	2.0e-04	15.1	COG2897	3-mercaptopyruvate sulfurtransferase SseA, contains two rhodanese domains	285
2918282658	331	68.99	6	127	28	116	5.1e-06	20.3	COG3677	Transposase	129
2918282661	395	94.7	1	377	19	393	1.8e-120	396.9	COG2807	Cyanate permease	395
2918282662	322	99.36	9	319	2	311	5.0e-114	375	COG0549	Carbamate kinase	312
2918282664	515	99.32	19	373	1	292	9.2e-65	213.4	COG0074	Succinyl-CoA synthetase, alpha subunit	293
2918282666	426	17.3	216	275	213	262	9.4e-06	9.8	COG4235	Cytochrome c-type biogenesis protein CcmH/NrfG	287
2918282666	426	18.18	135	229	204	263	2.5e-23	17.2	COG0666	Ankyrin repeat	235
2918282666	426	21.11	355	421	140	200	9.4e-06	7.7	COG4235	Cytochrome c-type biogenesis protein CcmH/NrfG	287
2918282666	426	21.8	299	398	140	202	9.4e-06	9.6	COG4235	Cytochrome c-type biogenesis protein CcmH/NrfG	287
2918282666	426	60.3	4	208	78	276	2.5e-23	61.8	COG0666	Ankyrin repeat	235
2918282668	985	66.5	149	578	128	389	1.2e-79	263.3	COG0642	Signal transduction histidine kinase	336
2918282668	985	84.96	585	709	5	117	1.5e-50	36.6	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918282668	985	94.74	734	973	5	130	1.5e-50	123.9	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918282669	460	97.22	1	459	7	460	0.0e+00	513	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2918282672	422	35.05	1	323	95	223	9.3e-12	40.3	COG0457	Tetratricopeptide (TPR) repeat	291
2918282673	624	8.33	117	206	81	132	2.5e-110	5.1	COG3914	Predicted O-linked N-acetylglucosamine transferase, SPINDLY family	620
2918282673	624	10.9	8	153	72	139	2.5e-110	8.1	COG3914	Predicted O-linked N-acetylglucosamine transferase, SPINDLY family	620
2918282673	624	58.65	218	621	256	621	2.5e-110	348	COG3914	Predicted O-linked N-acetylglucosamine transferase, SPINDLY family	620
2918282674	604	18.08	162	227	97	143	2.4e-20	8.9	COG5010	Flp pilus assembly protein TadD, contains TPR repeats	257
2918282674	604	33.08	79	171	116	201	2.4e-20	35.2	COG5010	Flp pilus assembly protein TadD, contains TPR repeats	257
2918282674	604	33.85	4	101	112	199	2.4e-20	42.1	COG5010	Flp pilus assembly protein TadD, contains TPR repeats	257
2918282674	604	61.37	247	601	154	404	5.8e-07	23.4	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918282675	507	24.62	9	85	109	172	1.1e-23	25.3	COG5010	Flp pilus assembly protein TadD, contains TPR repeats	257
2918282675	507	47.69	77	207	100	223	1.1e-23	56.9	COG5010	Flp pilus assembly protein TadD, contains TPR repeats	257
2918282676	620	45.65	7	269	106	273	3.9e-10	34.3	COG0457	Tetratricopeptide (TPR) repeat	291
2918282677	451	48.39	55	431	46	180	2.6e-05	18.7	COG0500	SAM-dependent methyltransferase	257
2918282678	927	84.29	309	911	97	622	0.0e+00	465.1	COG3914	Predicted O-linked N-acetylglucosamine transferase, SPINDLY family	620
2918282679	1274	63.32	750	1038	103	335	3.1e-17	56	COG0457	Tetratricopeptide (TPR) repeat	291
2918282680	402	60.39	95	401	154	400	6.7e-21	69.8	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918282681	932	67.39	350	730	99	346	3.5e-18	53.6	COG0457	Tetratricopeptide (TPR) repeat	291
2918282682	604	44.23	129	266	103	217	2.5e-28	54.2	COG5010	Flp pilus assembly protein TadD, contains TPR repeats	257
2918282682	604	46.92	2	141	99	220	2.5e-28	40	COG5010	Flp pilus assembly protein TadD, contains TPR repeats	257
2918282683	632	55.16	137	363	100	302	4.5e-24	31.6	COG0457	Tetratricopeptide (TPR) repeat	291
2918282683	632	56.52	3	199	151	358	4.5e-24	58.9	COG0457	Tetratricopeptide (TPR) repeat	291
2918282684	332	98.84	1	323	3	342	7.4e-119	390.4	COG1089	GDP-D-mannose dehydratase	345
2918282685	560	26.09	185	279	244	339	1.3e-19	24.5	COG0457	Tetratricopeptide (TPR) repeat	291
2918282685	560	45.38	2	187	190	356	1.3e-19	43	COG0457	Tetratricopeptide (TPR) repeat	291
2918282686	47	21.3	1	47	13	58	6.1e-16	53.2	COG3316	Transposase (or an inactivated derivative)	215
2918282687	231	87.04	8	162	14	154	6.2e-33	107.9	COG3666	Transposase	161
2918282688	464	56.79	7	425	62	270	1.2e-07	26.3	COG0457	Tetratricopeptide (TPR) repeat	291
2918282689	200	47.09	3	186	80	168	4.8e-12	40.3	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
2918282690	1264	64.75	246	436	49	206	1.3e-18	61.9	COG2114	Adenylate cyclase, class 3	227
2918282690	1264	77.86	2	229	29	246	1.8e-42	140.4	COG3629	DNA-binding transcriptional activator of the SARP family	280
2918282691	410	94.04	2	398	20	398	0.0e+00	440.6	COG3135	Predicted benzoate:H+ symporter BenE	402
2918282692	495	98.25	20	494	3	450	1.1e-124	411.2	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
2918282693	252	51.25	3	250	45	187	1.0e-09	33.4	COG0500	SAM-dependent methyltransferase	257
2918282695	265	94.14	17	255	7	231	3.3e-33	109.4	COG2188	DNA-binding transcriptional regulator, GntR family	236
2918282696	484	98.75	10	483	3	475	0.0e+00	523.2	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918282697	481	86.92	48	155	5	97	4.6e-11	36.3	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
2918282698	317	97.76	1	258	6	267	3.6e-62	204.1	COG1018	Ferredoxin-NADP reductase	266
2918282699	561	97.36	2	544	8	560	0.0e+00	491.8	COG2303	Choline dehydrogenase or related flavoprotein	542
2918282700	485	92.42	2	456	5	455	1.5e-68	226.6	COG3119	Arylsulfatase A or related enzyme	475
2918282701	438	50.39	8	204	3	195	8.2e-26	61.6	COG0477	MFS family permease	338
2918282701	438	51.96	205	436	8	206	8.2e-26	30.2	COG0477	MFS family permease	338
2918282702	237	89.47	5	237	27	247	4.3e-88	289	COG5530	Uncharacterized membrane protein	247
2918282703	654	96.05	312	654	3	221	7.3e-39	126.9	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
2918282704	186	86.99	16	184	19	145	1.9e-38	125.8	COG0071	Molecular chaperone IbpA, HSP20 family	146
2918282705	292	76.1	1	131	4	124	3.7e-17	13.9	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2918282705	292	88.68	137	292	16	156	3.7e-17	50.1	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2918282706	712	64.25	225	711	217	642	3.0e-94	310.6	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2918282707	326	86.58	3	320	43	358	6.2e-36	118.5	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
2918282708	352	32.01	220	339	202	298	5.5e-98	72.2	COG2354	Uncharacterized membrane protein MutK, may be involved in DNA repair	303
2918282708	352	67	1	227	3	205	5.5e-98	256.6	COG2354	Uncharacterized membrane protein MutK, may be involved in DNA repair	303
2918282709	214	93.78	1	206	8	203	3.1e-25	84.5	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918282710	154	96.18	2	153	6	156	1.3e-38	126.9	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
2918282711	145	93.43	3	139	5	132	5.1e-30	98.8	COG2764	Uncharacterized conserved protein PhnB, glyoxalase superfamily	136
2918282712	156	98.01	2	149	4	151	5.6e-45	147.5	COG3865	Glyoxalase superfamily enzyme, possibly 3-demethylubiquinone-9 3-methyltransferase	151
2918282713	121	99.15	1	121	1	116	1.4e-51	168.1	COG5507	Uncharacterized  conserved protein YbaA, DUF1428 family	117
2918282714	155	72.56	3	155	35	153	4.4e-17	53.4	COG2010	Cytochrome c, mono- and diheme variants	150
2918282715	168	79.19	21	168	19	136	4.4e-44	144.2	COG3019	Uncharacterized conserved protein	149
2918282717	260	78.11	2	248	58	289	9.6e-74	242.6	COG1533	DNA repair photolyase	297
2918282718	157	36.87	7	155	47	112	1.4e-10	35.9	COG3134	Uncharacterized conserved protein YcfJ, contains glycine zipper 2TM domain	179
2918282719	337	97.59	1	305	5	287	1.8e-77	254	COG1947	4-diphosphocytidyl-2C-methyl-D-erythritol kinase	289
2918282720	581	66.03	29	331	102	344	1.1e-27	32.1	COG0457	Tetratricopeptide (TPR) repeat	291
2918282720	581	74.73	294	579	73	347	1.1e-27	67	COG0457	Tetratricopeptide (TPR) repeat	291
2918282721	329	73.09	12	265	35	273	4.1e-12	40.1	COG3173	Predicted  kinase, aminoglycoside phosphotransferase (APT) family	321
2918282722	178	94.71	6	172	6	166	5.7e-64	208.9	COG0521	Molybdopterin biosynthesis enzyme MoaB	169
2918282723	653	98.68	329	628	3	301	2.7e-49	163.2	COG0741	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)	296
2918282724	287	97.03	93	287	4	199	3.6e-65	213.3	COG1573	Uracil-DNA glycosylase	202
2918282725	548	99.75	8	459	2	407	0.0e+00	438.2	COG0644	Dehydrogenase (flavoprotein)	396
2918282728	326	86.38	1	297	6	227	7.8e-12	37.3	COG3568	Metal-dependent hydrolase, endonuclease/exonuclease/phosphatase family	259
2918282729	219	93.29	33	196	7	159	4.0e-48	157.3	COG1871	Chemotaxis receptor (MCP) glutamine deamidase CheD	164
2918282730	470	10.71	385	447	416	466	7.1e-58	26.4	COG2027	D-alanyl-D-alanine carboxypeptidase	470
2918282730	470	78.36	1	375	10	382	7.1e-58	162.8	COG2027	D-alanyl-D-alanine carboxypeptidase	470
2918282731	241	84.3	15	231	20	207	3.7e-35	115.4	COG2091	Phosphopantetheinyl transferase	223
2918282732	324	98.91	17	300	4	275	4.1e-86	282.9	COG0152	Phosphoribosylaminoimidazole-succinocarboxamide synthase	247
2918282733	314	88.04	5	313	26	312	9.1e-82	268.8	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
2918282734	592	98.95	14	591	3	570	0.0e+00	617.7	COG1080	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria)	574
2918282735	114	95.51	27	114	4	88	1.3e-28	93.4	COG1925	Phosphotransferase system, HPr and related phosphotransfer proteins	88
2918282736	133	90.21	1	132	1	129	4.4e-43	140.9	COG2893	Phosphotransferase system, mannose/fructose-specific component IIA	143
2918282737	307	99.3	20	302	2	285	1.0e-94	311.6	COG1660	RNase adaptor protein for sRNA GlmZ degradation, contains a P-loop ATPase domain	286
2918282738	148	46.75	1	141	134	277	9.4e-32	105	COG1493	Serine kinase of the HPr protein, regulates carbohydrate metabolism	308
2918282739	118	40.12	17	110	23	91	1.5e-03	12.9	COG2318	Uncharacterized damage-inducible protein DinB (forms a four-helix bundle)	172
2918282740	598	84.52	183	598	56	388	2.4e-64	212.9	COG0642	Signal transduction histidine kinase	336
2918282741	231	98.28	3	231	2	229	6.8e-78	255.6	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918282742	284	95.14	33	272	9	243	2.9e-33	109.3	COG0748	Putative heme iron utilization protein	245
2918282743	607	98.03	1	599	12	607	0.0e+00	915.5	COG1274	Phosphoenolpyruvate carboxykinase, GTP-dependent	608
2918282744	286	97.75	1	284	3	263	4.9e-85	279.1	COG1291	Flagellar motor component MotA	266
2918282747	448	71.52	47	405	76	301	4.0e-54	178.8	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
2918282750	187	93.05	1	170	13	186	2.9e-20	67.7	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
2918282751	256	99.25	9	254	2	267	1.3e-60	199.7	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918282752	376	91.76	14	376	9	353	4.0e-45	148.9	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
2918282753	361	97.85	7	342	4	322	4.9e-74	243.5	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
2918282754	255	99.25	5	253	2	267	6.9e-47	154.7	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918282755	347	98.11	1	338	6	317	6.4e-40	129.7	COG3980	Spore coat polysaccharide biosynthesis protein SpsG, predicted glycosyltransferase	318
2918282756	258	81.31	1	240	3	263	7.2e-21	66.3	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2918282757	328	97.81	1	320	1	313	1.1e-75	249	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
2918282758	317	88.83	2	317	26	343	5.3e-89	292.8	COG1071	TPP-dependent pyruvate or acetoin dehydrogenase subunit alpha	358
2918282759	352	98.15	9	331	2	319	3.0e-107	352.7	COG0022	Pyruvate/2-oxoglutarate/acetoin dehydrogenase complex, dehydrogenase (E1) component	324
2918282760	426	97.87	28	423	7	373	1.5e-107	354.3	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
2918282761	334	98.75	3	317	3	319	2.6e-70	231.9	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2918282762	326	98.44	1	317	2	317	1.5e-58	193.3	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2918282763	622	50.61	230	532	148	354	9.0e-12	39.2	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918282767	342	24.58	218	338	237	324	9.7e-20	10.9	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
2918282767	342	39.94	53	249	18	160	9.7e-20	52.5	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
2918282768	348	96.54	1	344	12	346	4.0e-62	204.5	COG2089	Sialic acid synthase SpsE, contains C-terminal SAF domain	347
2918282769	258	97.93	1	239	3	238	5.7e-38	124.7	COG1861	Spore coat polysaccharide biosynthesis protein SpsF, cytidylyltransferase family	241
2918282770	330	96.01	1	329	5	341	1.9e-35	117.1	COG0673	Predicted dehydrogenase	342
2918282771	435	95.37	11	412	15	426	3.4e-99	326.5	COG0001	Glutamate-1-semialdehyde aminotransferase	432
2918282772	441	44.02	10	192	181	342	3.0e-26	29.4	COG0457	Tetratricopeptide (TPR) repeat	291
2918282772	441	73.91	154	433	74	345	3.0e-26	64.9	COG0457	Tetratricopeptide (TPR) repeat	291
2918282773	1005	26.24	753	990	156	213	1.2e-03	11.2	COG2755	Lysophospholipase L1 or related esterase	216
2918282773	1005	59.26	599	666	28	75	5.9e-09	29.5	COG0236	Acyl carrier protein	80
2918282773	1005	95.6	3	566	18	560	1.2e-71	235.7	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2918282774	218	60.53	37	218	72	186	6.3e-16	46.9	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
2918282775	199	97.33	13	197	5	186	4.4e-23	76.8	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
2918282776	79	88.89	1	74	6	77	1.3e-12	42.1	COG0236	Acyl carrier protein	80
2918282777	307	45.88	70	279	42	169	7.1e-09	30.1	COG0500	SAM-dependent methyltransferase	257
2918282778	614	68.92	165	588	154	550	5.9e-106	349.6	COG3882	Predicted enzyme involved in methoxymalonyl-ACP biosynthesis	574
2918282780	222	90.24	1	220	12	233	6.6e-28	92.5	COG2120	N-acetylglucosaminyl deacetylase, LmbE family	237
2918282781	307	92.21	1	294	2	285	3.8e-59	194.8	COG0223	Methionyl-tRNA formyltransferase	307
2918282782	387	95.83	1	380	4	371	1.2e-56	186.5	COG0381	UDP-N-acetylglucosamine 2-epimerase	383
2918282783	337	95.68	2	337	15	346	8.6e-110	361.2	COG2089	Sialic acid synthase SpsE, contains C-terminal SAF domain	347
2918282784	410	94.4	34	406	6	359	5.8e-102	335.9	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
2918282785	342	80.41	109	339	3	236	1.7e-25	83.8	COG1209	dTDP-glucose pyrophosphorylase	286
2918282786	339	98.44	4	328	3	318	1.8e-81	268.5	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2918282787	382	99.7	1	326	1	332	1.7e-89	294.9	COG2605	Predicted kinase related to galactokinase and mevalonate kinase	333
2918282788	326	94.77	1	319	14	339	2.4e-63	205.3	COG1089	GDP-D-mannose dehydratase	345
2918282790	1572	43.21	205	349	184	342	3.5e-99	49.9	COG0457	Tetratricopeptide (TPR) repeat	291
2918282790	1572	56.79	735	942	131	339	3.5e-99	67.5	COG0457	Tetratricopeptide (TPR) repeat	291
2918282790	1572	58.7	1080	1308	143	358	3.5e-99	56.3	COG0457	Tetratricopeptide (TPR) repeat	291
2918282790	1572	61.68	280	477	100	326	3.5e-99	63.1	COG0457	Tetratricopeptide (TPR) repeat	291
2918282790	1572	64.67	2	208	101	338	3.5e-99	76	COG0457	Tetratricopeptide (TPR) repeat	291
2918282790	1572	75.27	891	1114	67	343	3.5e-99	82.1	COG0457	Tetratricopeptide (TPR) repeat	291
2918282791	648	63.59	2	167	110	343	1.9e-30	54.4	COG0457	Tetratricopeptide (TPR) repeat	291
2918282791	648	71.2	129	376	97	358	1.9e-30	61	COG0457	Tetratricopeptide (TPR) repeat	291
2918282792	675	95.19	2	609	30	623	0.0e+00	643.1	COG3914	Predicted O-linked N-acetylglucosamine transferase, SPINDLY family	620
2918282795	558	19.62	11	65	14	54	6.3e-14	16.9	COG4133	ABC-type transport system involved in cytochrome c biogenesis, ATPase component	209
2918282795	558	63.64	261	419	71	203	6.3e-14	27.6	COG4133	ABC-type transport system involved in cytochrome c biogenesis, ATPase component	209
2918282796	517	37.28	212	397	228	378	2.7e-20	24.1	COG0732	Restriction endonuclease S subunit	391
2918282796	517	41.98	1	169	204	373	2.7e-20	41.7	COG0732	Restriction endonuclease S subunit	391
2918282797	476	9.56	6	62	5	54	4.5e-71	10.6	COG0286	Type I restriction-modification system, DNA methylase subunit	489
2918282797	476	59.27	92	448	142	451	4.5e-71	222.3	COG0286	Type I restriction-modification system, DNA methylase subunit	489
2918282798	755	25.05	439	613	287	408	1.7e-08	3.5	COG1061	Superfamily II DNA or RNA helicase	442
2918282798	755	29.98	187	412	35	180	1.7e-08	22.8	COG1061	Superfamily II DNA or RNA helicase	442
2918282802	290	93.29	1	287	1	264	4.3e-47	155.1	COG3649	CRISPR/Cas system type I-B associated protein Csh2, Cas7 group, RAMP superfamily	283
2918282803	218	90.36	12	199	19	196	1.3e-26	88.3	COG1468	CRISPR/Cas system-associated exonuclease Cas4, RecB family	190
2918282804	345	99.09	4	344	4	328	1.1e-80	265.6	COG1518	CRISPR/Cas system-associated endonuclease Cas1	327
2918282805	96	97.75	1	93	1	87	8.7e-25	81.6	COG1343	CRISPR/Cas system-associated endoribonuclease Cas2	89
2918282806	825	71.2	704	820	25	113	1.0e-13	45.6	COG2198	HPt (histidine-containing phosphotransfer) domain	122
2918282806	825	72.34	162	562	106	390	4.4e-58	192.5	COG0642	Signal transduction histidine kinase	336
2918282806	825	91.73	583	713	6	127	7.8e-36	116.1	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918282807	231	98.28	4	228	3	230	8.0e-64	209.7	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918282808	1139	19.29	1003	1102	374	481	5.0e-37	36.9	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918282808	1139	20.89	99	250	415	531	5.0e-37	23.8	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918282808	1139	50.71	634	1040	170	453	5.0e-37	27.9	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918282808	1139	63.57	222	612	121	476	5.0e-37	53.6	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918282809	176	86.02	1	161	20	179	1.9e-44	146.1	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918282810	300	96.89	1	297	3	251	1.3e-16	53.8	COG5662	Transmembrane transcriptional regulator (anti-sigma factor RsiW)	256
2918282811	240	92.67	2	240	16	230	8.9e-74	242.4	COG0670	Integral membrane protein, interacts with FtsH	233
2918282812	397	65.61	8	136	6	108	5.2e-08	26.8	COG1225	Peroxiredoxin	157
2918282813	369	70.56	7	364	110	387	1.5e-57	190.5	COG0642	Signal transduction histidine kinase	336
2918282814	200	99.05	5	199	2	210	5.0e-41	132.5	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918282815	150	89.33	1	148	2	135	5.8e-43	141	COG1959	DNA-binding transcriptional regulator, IscR family	150
2918282816	210	92.69	1	210	15	255	1.7e-52	173.2	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2918282818	168	79.56	25	167	18	126	1.3e-09	32.1	COG1765	Uncharacterized OsmC-related protein	137
2918282819	363	99.17	1	357	1	360	0.0e+00	513.9	COG4663	TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component	363
2918282820	332	96.31	10	331	11	323	2.0e-121	399.5	COG0379	Quinolinate synthase	324
2918282821	550	97.12	5	538	7	511	0.0e+00	551.2	COG0029	Aspartate oxidase	518
2918282822	277	97.86	2	277	4	277	1.7e-108	356.5	COG0157	Nicotinate-nucleotide pyrophosphorylase	280
2918282823	443	98.09	7	425	6	415	6.9e-98	323	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
2918282824	433	98.59	1	433	4	424	0.0e+00	670.9	COG3508	Homogentisate 1,2-dioxygenase	427
2918282825	309	95.76	5	308	6	321	2.5e-56	185.7	COG2423	Ornithine cyclodeaminase/archaeal alanine dehydrogenase, mu-crystallin family	330
2918282826	1240	99.22	471	1240	6	772	0.0e+00	1151	COG4230	Delta 1-pyrroline-5-carboxylate dehydrogenase	769
2918282826	1240	99.75	54	472	2	403	0.0e+00	524.4	COG0506	Proline dehydrogenase	391
2918282827	153	94.3	1	153	4	152	2.9e-46	152.1	COG1522	DNA-binding transcriptional regulator, Lrp family	154
2918282828	108	96.33	1	108	4	108	8.5e-43	139.6	COG1742	Uncharacterized inner membrane protein YnfA, drug/metabolite transporter superfamily	109
2918282829	146	95.45	5	122	2	127	7.1e-33	108.1	COG0789	DNA-binding transcriptional regulator, MerR family	124
2918282830	213	67.89	2	209	16	218	3.3e-34	113	COG1230	Co/Zn/Cd efflux system component	296
2918282831	187	97.37	1	187	4	188	1.6e-48	159.4	COG1971	Putative Mn2+ efflux pump MntP	190
2918282833	337	90.83	3	337	30	346	0.0e+00	545.8	COG1613	ABC-type sulfate transport system, periplasmic component	348
2918282834	277	98.18	2	276	3	271	4.3e-106	348.3	COG0555	ABC-type sulfate transport system, permease component	274
2918282835	285	95.47	1	285	11	284	0.0e+00	456.4	COG4208	ABC-type sulfate transport system, permease component	287
2918282836	346	99.43	1	346	1	348	0.0e+00	438.2	COG1118	ABC-type sulfate/molybdate transport systems, ATPase component	345
2918282841	579	73.09	383	573	23	185	1.6e-30	101.3	COG1226	Voltage-gated potassium channel Kch	212
2918282841	579	96.5	1	392	6	391	3.5e-91	300.3	COG0475	Kef-type K+ transport system, membrane component KefB	397
2918282842	67	17.79	1	59	8	57	5.6e-03	11.1	COG4395	Predicted lipid-binding transport protein, Tim44 family	281
2918282843	123	92.48	1	123	5	127	7.6e-28	91.6	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918282844	167	69.92	7	137	4	96	4.3e-17	56.9	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918282845	284	92.94	3	274	12	248	5.8e-41	134.6	COG2746	Aminoglycoside N3'-acetyltransferase	251
2918282846	252	99.21	1	252	1	250	1.7e-100	330.4	COG4604	ABC-type enterochelin transport system, ATPase component	252
2918282847	315	98.42	1	315	2	312	1.0e-97	321.7	COG4605	ABC-type enterochelin transport system, permease component	316
2918282848	322	95.64	8	322	10	316	1.9e-111	366.8	COG4606	ABC-type enterochelin transport system, permease component	321
2918282849	308	86.56	23	305	43	319	1.0e-81	268.7	COG4607	ABC-type enterochelin transport system, periplasmic component	320
2918282850	287	87.41	1	270	1	243	5.0e-33	109.2	COG1082	Sugar phosphate isomerase/epimerase	274
2918282851	427	60.49	2	81	27	75	3.2e-07	24.1	COG0236	Acyl carrier protein	80
2918282852	415	64.49	70	415	187	542	3.3e-36	107.7	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
2918282853	581	77.91	71	567	108	576	8.7e-93	306.2	COG4264	Siderophore synthetase component	602
2918282854	602	97.18	1	582	14	598	2.3e-91	300.9	COG4264	Siderophore synthetase component	602
2918282855	99	97.92	1	96	1	94	1.3e-23	77.8	COG3553	Uncharacterized protein	96
2918282856	744	98.36	66	744	14	795	4.6e-37	122.9	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2918282857	327	98.14	9	327	4	320	1.5e-80	265	COG3712	Periplasmic ferric-dicitrate binding protein FerR, regulates iron transport through sigma-19	322
2918282858	171	87.1	1	170	17	178	4.5e-33	109	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918282859	568	99.16	1	568	4	590	0.0e+00	593.5	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
2918282860	194	83.1	5	194	34	210	2.9e-42	138.9	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
2918282862	186	48.15	2	163	58	148	1.6e-06	21.4	COG3945	Hemerythrin-like domain	189
2918282864	938	40.91	17	125	144	242	1.1e-53	16.5	COG2202	PAS domain	232
2918282864	938	57.85	401	535	103	242	1.1e-53	83.7	COG2202	PAS domain	232
2918282864	938	59.5	122	409	99	242	1.1e-53	89.7	COG2202	PAS domain	232
2918282864	938	73.55	524	804	88	354	4.4e-24	79.2	COG3852	Signal transduction histidine kinase, nitrogen specific	363
2918282867	41	17.13	1	41	30	66	2.0e-11	38	COG3316	Transposase (or an inactivated derivative)	215
2918282868	401	97.91	4	369	5	378	1.1e-119	393.8	COG3448	CBS-domain-containing membrane protein	382
2918282869	497	96.69	11	494	10	477	0.0e+00	745.6	COG3278	Cbb3-type cytochrome oxidase, subunit 1	482
2918282870	292	97.01	1	282	1	292	1.5e-48	160.2	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918282872	354	98.64	61	339	3	293	1.2e-47	157.4	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918282874	187	94.02	2	187	2	174	4.5e-47	154.8	COG0431	NAD(P)H-dependent FMN reductase	184
2918282875	282	78.36	7	254	4	213	6.4e-44	145.1	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918282876	329	92.5	10	321	15	310	1.9e-62	205.4	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
2918282877	298	94.96	36	297	9	253	6.1e-61	200.5	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2918282878	279	98.01	18	272	3	248	2.5e-83	273.9	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2918282879	302	98.26	5	286	4	285	2.0e-82	271.4	COG2175	Taurine dioxygenase, alpha-ketoglutarate-dependent	286
2918282880	338	92.84	1	336	13	323	2.8e-33	110.1	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918282881	282	97.56	5	282	4	283	9.3e-89	292.2	COG2175	Taurine dioxygenase, alpha-ketoglutarate-dependent	286
2918282882	280	94.96	22	280	12	256	5.6e-79	259.7	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2918282883	260	91.89	1	260	17	254	5.8e-112	368.1	COG4525	ABC-type taurine transport system, ATPase component	259
2918282885	338	95.81	1	336	13	332	0.0e+00	502.5	COG4521	ABC-type taurine transport system, periplasmic component	334
2918282886	343	89.25	13	340	8	306	6.0e-46	151.7	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918282887	327	96.9	69	324	6	255	4.4e-48	158.7	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2918282888	262	95.62	14	260	5	244	3.1e-91	299.7	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2918282891	264	98.84	3	260	2	256	1.3e-82	271.5	COG1120	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	258
2918282892	289	84.18	3	288	52	333	2.0e-86	284.6	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
2918282893	328	87.35	5	294	41	323	3.2e-49	162.4	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
2918282894	518	90.82	48	512	38	423	2.6e-61	200.8	COG0840	Methyl-accepting chemotaxis protein	408
2918282895	320	98.42	1	306	1	311	3.1e-64	211.5	COG0524	Sugar or nucleoside kinase, ribokinase family	311
2918282896	156	98.01	1	149	1	148	5.4e-55	179.8	COG0698	Ribose 5-phosphate isomerase RpiB	151
2918282897	424	99.21	45	424	3	378	0.0e+00	444.8	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
2918282898	155	83.05	1	154	11	157	1.4e-29	97.3	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
2918282899	331	92.77	2	331	9	316	2.7e-88	290.9	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
2918282900	271	92.95	6	242	10	233	3.3e-52	171.7	COG2186	DNA-binding transcriptional regulator, FadR family	241
2918282903	279	89.35	1	272	5	264	2.0e-68	225.2	COG2513	2-Methylisocitrate lyase and related enzymes, PEP mutase family	289
2918282904	343	98.8	8	341	3	332	2.0e-82	271.1	COG2855	Uncharacterized membrane protein YadS	334
2918282905	297	96.35	1	294	2	291	3.5e-68	225	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918282909	416	67.82	1	408	1	274	9.8e-52	170.4	COG0420	DNA repair exonuclease SbcCD nuclease subunit	390
2918282910	1261	99.89	1	1236	1	948	1.6e-113	370.3	COG0419	DNA repair exonuclease SbcCD ATPase subunit	908
2918282911	750	83.22	493	750	36	273	2.5e-31	102.5	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
2918282911	750	95.7	24	493	19	463	6.6e-105	345.7	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
2918282912	280	94.47	10	266	9	247	4.2e-72	236.7	COG1922	UDP-N-acetyl-D-mannosaminuronic acid transferase, WecB/TagA/CpsF family	253
2918282913	475	88	252	474	23	220	2.4e-75	246.7	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
2918282915	442	68.07	2	421	111	402	8.5e-17	54.9	COG3307	O-antigen ligase	424
2918282916	351	92.71	1	351	19	374	1.0e-115	381.2	COG0381	UDP-N-acetylglucosamine 2-epimerase	383
2918282917	720	16.81	174	250	8	66	2.1e-53	6.8	COG0673	Predicted dehydrogenase	342
2918282917	720	97.72	393	720	5	347	2.1e-53	175.3	COG0673	Predicted dehydrogenase	342
2918282918	211	61.29	6	208	54	224	7.3e-13	43.7	COG0500	SAM-dependent methyltransferase	257
2918282920	483	88.59	5	464	7	433	1.3e-28	94.2	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
2918282921	636	98.72	1	632	2	542	6.7e-124	408.9	COG0367	Asparagine synthetase B (glutamine-hydrolyzing)	542
2918282924	379	71.39	14	378	106	397	4.4e-37	123.2	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918282925	429	95.41	10	429	10	425	0.0e+00	511.9	COG0677	UDP-N-acetyl-D-mannosaminuronate dehydrogenase	436
2918282926	442	82.91	24	442	78	465	7.1e-63	207.5	COG5338	Uncharacterized protein	468
2918282927	235	61.39	79	224	55	151	2.7e-07	25.1	COG0639	Diadenosine tetraphosphatase ApaH/serine/threonine protein phosphatase, PP2A family	155
2918282929	191	66.27	21	191	37	201	1.5e-37	123.7	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
2918282932	358	96.97	94	352	4	259	2.5e-69	228.2	COG1192	Cellulose biosynthesis protein BcsQ	259
2918282933	291	95.83	33	289	5	257	1.1e-42	141.1	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
2918282934	148	38.07	15	147	56	181	4.0e-25	83.4	COG0790	TPR repeat	292
2918282935	174	95.86	4	170	1	162	7.8e-25	82.6	COG3663	G:T/U-mismatch repair DNA glycosylase	169
2918282936	154	65.98	1	132	4	131	4.9e-18	59.8	COG3707	Two-component response regulator, AmiR/NasT family, consists of REC and RNA-binding antiterminator (ANTAR) domains	194
2918282937	554	96.81	292	549	3	245	0.0e+00	283.8	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2918282937	554	98.01	1	256	2	247	0.0e+00	291.2	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2918282938	362	94.96	54	362	8	252	1.1e-57	185.5	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2918282939	472	98.51	5	381	4	333	1.8e-68	225.5	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918282940	823	99.38	10	818	2	797	0.0e+00	1212.6	COG1251	NAD(P)H-nitrite reductase, large subunit	793
2918282941	120	95.33	8	111	3	104	4.8e-28	91.6	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
2918282942	886	84.13	829	886	3	55	1.7e-08	28.2	COG2906	Bacterioferritin-associated ferredoxin	63
2918282942	886	94.44	1	704	44	808	0.0e+00	582.2	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
2918282943	311	97.13	52	297	3	239	5.1e-81	266.4	COG0007	Uroporphyrinogen-III methylase (siroheme synthase)	244
2918282944	262	40.56	69	256	136	236	2.7e-17	58.4	COG0791	Cell wall-associated hydrolase, NlpC family	197
2918282946	354	99.41	6	353	3	340	4.5e-85	280.3	COG2222	Fructoselysine-6-P-deglycase FrlB and related proteins with duplicated sugar isomerase (SIS) domain	340
2918282947	264	98.58	36	263	2	209	1.2e-48	159.8	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918282948	691	99.6	42	634	1	496	0.0e+00	537.5	COG1032	Radical SAM superfamily enzyme YgiQ, UPF0313 family	490
2918282950	203	24.72	107	163	35	78	3.0e-06	13.8	COG1633	Rubrerythrin	176
2918282950	203	26.97	9	80	123	170	3.0e-06	6.3	COG1633	Rubrerythrin	176
2918282952	315	80.92	164	302	20	142	7.7e-13	37.2	COG5616	TolB amino-terminal domain (function unknown)	152
2918282953	184	93.51	5	184	12	184	1.1e-35	117.9	COG3108	Uncharacterized conserved protein YcbK, DUF882 family	185
2918282959	371	92.29	1	362	4	338	8.6e-120	394.8	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
2918282963	57	67.16	2	56	12	56	7.6e-07	24	COG5481	Uncharacterized protein	67
2918282964	216	74.56	15	215	48	217	3.4e-44	145.5	COG3485	Protocatechuate 3,4-dioxygenase beta subunit	226
2918282965	235	97.71	15	234	4	216	8.2e-66	216.5	COG0819	Thiaminase	218
2918282966	246	98.13	1	244	4	266	2.5e-73	241.5	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918282967	243	90.32	15	210	12	179	7.9e-45	147.2	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918282969	172	70.31	5	139	38	127	2.4e-21	70.9	COG3794	Plastocyanin	128
2918282971	73	83.08	7	68	7	60	1.1e-17	58.1	COG3024	Endogenous inhibitor of DNA gyrase, YacG/DUF329 family	65
2918282972	386	78.53	3	385	14	397	2.3e-80	264.9	COG1530	Ribonuclease G or E	487
2918282973	199	96.91	3	199	3	190	2.2e-59	194.6	COG0424	Predicted house-cleaning NTP pyrophosphatase, Maf/HAM1 superfamily	193
2918282974	72	96	1	72	1	72	4.1e-35	113.8	COG0361	Translation initiation factor IF-1	75
2918282976	760	61.54	623	757	13	124	3.4e-05	17.2	COG4567	Two-component response regulator, ActR/RegA family, consists of REC and Fis-type HTH domains	182
2918282976	760	83.5	226	610	64	392	2.9e-86	285.1	COG0642	Signal transduction histidine kinase	336
2918282977	153	96.62	9	145	3	145	2.7e-28	93.6	COG0394	Protein-tyrosine-phosphatase	139
2918282978	160	96.88	1	160	6	160	5.3e-71	232.5	COG5328	Uncharacterized protein, UPF0262 family	160
2918282979	435	96.74	3	432	11	425	0.0e+00	566.9	COG0141	Histidinol dehydrogenase	425
2918282980	241	74.74	24	241	2	220	3.0e-60	198.6	COG0040	ATP phosphoribosyltransferase	290
2918282983	258	96.67	1	258	10	270	3.0e-94	309.6	COG1464	ABC-type metal ion transport system, periplasmic component/surface antigen	268
2918282984	556	97.01	18	554	10	560	4.0e-117	386.2	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2918282985	354	99.71	1	344	1	339	0.0e+00	465	COG1135	ABC-type methionine transport system, ATPase component	339
2918282986	222	96.4	1	218	9	222	4.0e-92	302.2	COG2011	ABC-type methionine transport system, permease component	222
2918282987	266	97.78	1	266	7	270	6.0e-114	374.2	COG1464	ABC-type metal ion transport system, periplasmic component/surface antigen	268
2918282988	1267	25.38	812	884	104	169	2.1e-53	25	COG5010	Flp pilus assembly protein TadD, contains TPR repeats	257
2918282988	1267	28.08	2	89	93	165	2.1e-53	7.5	COG5010	Flp pilus assembly protein TadD, contains TPR repeats	257
2918282988	1267	36.15	83	188	104	197	2.1e-53	49.6	COG5010	Flp pilus assembly protein TadD, contains TPR repeats	257
2918282988	1267	38.08	764	865	126	224	2.1e-53	23.4	COG5010	Flp pilus assembly protein TadD, contains TPR repeats	257
2918282988	1267	46.54	168	295	110	230	2.1e-53	67.4	COG5010	Flp pilus assembly protein TadD, contains TPR repeats	257
2918282988	1267	51.54	831	981	55	188	2.1e-53	34.4	COG5010	Flp pilus assembly protein TadD, contains TPR repeats	257
2918282988	1267	56.54	593	764	73	219	2.1e-53	35.7	COG5010	Flp pilus assembly protein TadD, contains TPR repeats	257
2918282989	560	55.56	1	83	42	106	4.6e-03	9.8	COG3462	Uncharacterized membrane protein	117
2918282989	560	84.94	160	555	63	423	2.9e-59	193.7	COG0840	Methyl-accepting chemotaxis protein	408
2918282990	430	26.69	357	427	134	200	1.2e-68	50.1	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2918282990	430	29.08	260	355	106	178	1.2e-68	48.4	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2918282990	430	35.46	129	234	126	214	1.2e-68	78.6	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2918282990	430	39.44	4	138	89	187	1.2e-68	65.4	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2918282991	718	58.76	582	717	8	121	5.9e-07	22.7	COG3707	Two-component response regulator, AmiR/NasT family, consists of REC and RNA-binding antiterminator (ANTAR) domains	194
2918282991	718	80.2	158	568	76	391	1.0e-55	183.9	COG0642	Signal transduction histidine kinase	336
2918282992	756	97.73	9	716	10	697	0.0e+00	925.1	COG1523	Pullulanase/glycogen debranching enzyme	697
2918282995	92	39.1	1	85	16	67	2.4e-06	22.3	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918282996	253	99.57	1	230	1	229	1.2e-92	304.3	COG0588	Phosphoglycerate mutase (BPG-dependent)	230
2918282998	260	87.75	10	245	24	245	2.3e-39	129.5	COG1922	UDP-N-acetyl-D-mannosaminuronic acid transferase, WecB/TagA/CpsF family	253
2918282999	786	65.38	541	784	43	229	1.3e-27	90.5	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
2918282999	786	97.63	32	527	10	463	5.4e-75	246.5	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
2918283000	426	81.59	18	423	60	347	1.1e-44	147.2	COG3693	Endo-1,4-beta-xylanase, GH35 family	345
2918283001	306	59.86	21	298	54	220	1.5e-12	42.6	COG0500	SAM-dependent methyltransferase	257
2918283002	845	88.65	283	678	16	390	2.3e-53	176	COG2730	Aryl-phospho-beta-D-glucosidase BglC, GH1 family	407
2918283005	253	64.79	1	159	9	100	6.0e-06	17.9	COG0727	Fe-S-cluster containining protein	132
2918283006	157	97.35	1	157	4	150	2.8e-42	138.7	COG3012	Uncharacterized conserved protein YchJ, contains N- and C-terminal SEC-C domains	151
2918283007	673	72.34	162	515	106	390	1.4e-58	194.1	COG0642	Signal transduction histidine kinase	336
2918283007	673	92.48	537	665	8	130	4.9e-15	48.3	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918283009	147	95.04	1	141	5	138	3.3e-39	128.9	COG3193	Uncharacterized conserved protein GlcG, DUF336 family	141
2918283010	367	86.92	4	366	54	412	1.0e-113	374.9	COG2133	Glucose/arabinose dehydrogenase, beta-propeller fold	399
2918283011	822	89.63	3	815	45	770	1.7e-80	263.5	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
2918283012	176	78.33	11	164	23	163	8.6e-16	52.5	COG0723	Rieske Fe-S protein	177
2918283013	314	98.67	11	304	2	298	1.8e-60	199.8	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918283014	407	12.25	30	92	28	82	2.7e-22	11.9	COG2610	H+/gluconate symporter or related permease	442
2918283014	407	68.15	96	405	143	448	2.7e-22	65.5	COG2610	H+/gluconate symporter or related permease	442
2918283015	118	75.42	1	100	19	107	4.3e-09	31.4	COG0640	DNA-binding transcriptional regulator, ArsR family	110
2918283016	279	93.54	8	278	17	320	1.9e-53	176.1	COG0226	ABC-type phosphate transport system, periplasmic component	318
2918283017	293	89.49	7	289	26	306	5.3e-69	226.9	COG0573	ABC-type phosphate transport system, permease component	310
2918283018	285	90.48	3	278	21	286	3.0e-71	234.2	COG0581	ABC-type phosphate transport system, permease component	292
2918283019	249	96.06	1	249	10	253	2.1e-99	326.6	COG1117	ABC-type phosphate transport system, ATPase component	253
2918283020	435	95.35	12	426	17	426	8.2e-121	397.9	COG0128	5-enolpyruvylshikimate-3-phosphate synthase	428
2918283021	486	98.82	1	484	5	507	2.6e-81	267.7	COG0696	Phosphoglycerate mutase (BPG-independent, AlkP superfamily)	509
2918283022	470	98.75	1	470	4	476	0.0e+00	450.1	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918283023	385	89.53	1	164	8	161	9.2e-34	111	COG4032	Sulfopyruvate decarboxylase, TPP-binding subunit (coenzyme M biosynthesis)	172
2918283024	276	42.31	33	271	136	278	6.0e-08	27.1	COG1305	Transglutaminase-like enzyme, putative cysteine protease	319
2918283025	363	18.41	155	236	116	159	2.2e-20	22.3	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
2918283025	363	32.64	56	161	50	127	2.2e-20	43.2	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
2918283026	277	97.48	1	276	1	271	4.0e-119	391.5	COG1348	Nitrogenase subunit NifH, an ATPase	278
2918283027	444	71.4	30	400	35	361	3.4e-51	168.6	COG2710	Nitrogenase molybdenum-iron protein, alpha and beta chains	456
2918283028	435	89.96	16	434	29	440	1.6e-49	163.1	COG2710	Nitrogenase molybdenum-iron protein, alpha and beta chains	456
2918283030	345	69.55	35	340	4	252	2.1e-55	182.8	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
2918283031	138	84.75	7	109	7	106	7.5e-14	46.7	COG0640	DNA-binding transcriptional regulator, ArsR family	110
2918283032	358	96.5	13	358	9	339	4.1e-108	355.8	COG0798	Arsenite efflux pump ArsB, ACR3 family	342
2918283033	194	86.02	3	176	20	179	1.1e-43	143.4	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918283034	161	36.29	81	137	57	101	1.4e-15	16.8	COG0599	Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family	124
2918283034	161	42.74	1	73	51	103	1.4e-15	37.9	COG0599	Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family	124
2918283037	652	66.58	262	614	22	266	3.5e-05	18.6	COG0457	Tetratricopeptide (TPR) repeat	291
2918283038	470	98.29	15	470	5	463	0.0e+00	470.8	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2918283039	494	90.1	62	486	36	390	1.6e-37	124.8	COG0642	Signal transduction histidine kinase	336
2918283040	278	76.74	2	274	54	284	9.7e-28	91.8	COG3221	ABC-type phosphate/phosphonate transport system, periplasmic component	299
2918283041	313	66.23	39	213	51	201	5.4e-07	23.4	COG5014	Uncharacterized Fe-S cluster-containing protein, radical SAM superfamily	228
2918283042	289	82.21	2	260	30	260	2.0e-48	159.9	COG3000	Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily	271
2918283043	316	94.43	43	315	8	278	1.8e-43	143.1	COG2897	3-mercaptopyruvate sulfurtransferase SseA, contains two rhodanese domains	285
2918283044	173	97.3	5	143	2	145	4.1e-23	76.6	COG0394	Protein-tyrosine-phosphatase	139
2918283045	357	97.08	10	357	8	340	4.8e-111	365.5	COG0798	Arsenite efflux pump ArsB, ACR3 family	342
2918283046	413	51.7	212	412	14	211	3.4e-05	7.9	COG0477	MFS family permease	338
2918283046	413	68.67	4	258	16	278	3.4e-05	13.1	COG0477	MFS family permease	338
2918283047	335	98.81	2	335	1	331	1.5e-118	390.6	COG0057	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase	335
2918283048	124	78.81	1	99	16	108	3.0e-13	44.8	COG0640	DNA-binding transcriptional regulator, ArsR family	110
2918283050	116	69.23	8	114	2	91	3.7e-17	57.8	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918283054	63	18.56	11	61	2	37	1.4e-06	22.5	COG2452	Predicted site-specific integrase-resolvase	193
2918283055	576	52.54	312	566	146	321	1.9e-05	19.5	COG0582	Integrase	309
2918283056	358	56.42	43	350	128	316	3.8e-09	30.6	COG0582	Integrase	309
2918283058	226	23.89	30	222	85	165	3.0e-06	21	COG1442	Lipopolysaccharide biosynthesis protein, LPS:glycosyltransferase	325
2918283061	541	14.23	192	236	152	188	1.8e-27	14.6	COG5010	Flp pilus assembly protein TadD, contains TPR repeats	257
2918283061	541	27.31	128	203	121	191	1.8e-27	34.8	COG5010	Flp pilus assembly protein TadD, contains TPR repeats	257
2918283061	541	38.46	10	125	81	180	1.8e-27	51.2	COG5010	Flp pilus assembly protein TadD, contains TPR repeats	257
2918283062	499	13.75	125	212	394	470	8.3e-54	37.6	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918283062	499	24.82	1	126	300	438	8.3e-54	46.2	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918283062	499	28.57	203	350	294	453	8.3e-54	59.2	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918283062	499	47.86	252	495	292	559	8.3e-54	77.4	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918283064	642	87.5	54	638	76	621	6.9e-114	374.8	COG3914	Predicted O-linked N-acetylglucosamine transferase, SPINDLY family	620
2918283065	546	70.11	13	287	102	359	1.0e-17	59	COG0457	Tetratricopeptide (TPR) repeat	291
2918283066	404	82.4	3	404	71	407	7.9e-29	96.1	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918283069	310	44.29	2	255	3	161	2.2e-31	104.7	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
2918283070	349	54.47	95	342	116	316	6.2e-33	108.7	COG4421	Capsular polysaccharide biosynthesis protein	368
2918283071	322	98.44	12	317	3	318	1.0e-72	239.8	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2918283072	356	99.13	2	348	2	342	0.0e+00	570.9	COG1089	GDP-D-mannose dehydratase	345
2918283073	478	93.02	350	476	9	128	4.0e-42	137.1	COG0662	Mannose-6-phosphate isomerase, cupin superfamily	127
2918283073	478	99.7	8	341	2	335	7.8e-130	427.6	COG0836	Mannose-1-phosphate guanylyltransferase	333
2918283076	211	35.94	1	210	381	596	2.3e-70	232.4	COG1086	NDP-sugar epimerase, includes UDP-GlcNAc-inverting 4,6-dehydratase FlaA1 and capsular polysaccharide biosynthesis protein EpsC	588
2918283077	257	56.53	4	243	5	216	4.9e-66	217.7	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
2918283078	119	30.67	1	117	259	373	9.2e-23	75.6	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
2918283080	336	97.57	8	335	3	323	0.0e+00	433.9	COG1087	UDP-glucose 4-epimerase	329
2918283081	183	96.61	1	178	7	177	1.7e-69	227.4	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase or related enzyme	173
2918283082	359	98	2	349	3	345	0.0e+00	533.4	COG1088	dTDP-D-glucose 4,6-dehydratase	340
2918283083	302	99.29	1	295	2	281	9.5e-104	341	COG1091	dTDP-4-dehydrorhamnose reductase	281
2918283084	287	98.63	1	287	1	287	2.3e-123	405.4	COG1209	dTDP-glucose pyrophosphorylase	286
2918283085	317	98.44	1	316	3	318	1.5e-76	252.5	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2918283086	344	78	3	343	88	406	5.8e-22	73.6	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918283088	330	98.13	6	327	3	317	2.1e-63	209.2	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2918283090	375	94.67	8	375	18	372	8.8e-105	345.3	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
2918283091	102	83.76	1	102	6	103	3.7e-21	70.4	COG2963	Transposase and inactivated derivatives	116
2918283096	406	55.99	62	403	172	400	1.8e-20	68.6	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918283097	676	93.89	8	395	7	390	5.4e-16	53.3	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918283098	357	34.81	39	269	190	299	9.9e-28	92.3	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
2918283100	524	14.46	407	484	404	484	1.4e-34	47.4	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918283100	524	51.61	47	416	169	457	1.4e-34	75.8	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918283101	113	13.59	3	103	297	346	9.6e-05	17.6	COG0457	Tetratricopeptide (TPR) repeat	291
2918283103	211	69.33	2	181	69	224	2.8e-22	73.7	COG2057	Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit	225
2918283105	261	98.13	8	249	4	266	1.4e-59	196.4	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918283106	211	46.72	15	143	9	72	3.4e-03	10.9	COG4319	Ketosteroid isomerase homolog	137
2918283107	364	91.74	3	360	4	336	5.3e-98	323	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
2918283108	230	90.91	1	200	13	202	4.7e-25	83.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918283109	252	98.51	4	250	3	266	6.3e-62	204	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918283110	413	78.75	337	406	15	77	1.5e-13	43.6	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2918283111	412	86.89	19	399	9	326	2.9e-45	149.4	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918283112	158	93.53	3	141	6	135	4.4e-22	73.1	COG0824	Acyl-CoA thioesterase FadM	137
2918283113	258	97.01	9	257	8	267	2.3e-44	146.4	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918283114	521	96.48	1	520	11	558	3.8e-110	363.4	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2918283115	252	98.13	8	250	5	267	6.8e-75	246.5	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918283116	249	98.85	1	249	1	258	1.0e-91	301.4	COG2086	Electron transfer flavoprotein, alpha and beta subunits	260
2918283118	310	98.43	1	310	3	315	1.6e-111	367.6	COG2025	Electron transfer flavoprotein, alpha subunit	313
2918283119	546	99.51	6	457	3	407	1.3e-130	430.6	COG0644	Dehydrogenase (flavoprotein)	396
2918283121	261	98.49	1	258	5	265	2.1e-71	235	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918283122	233	76.56	18	224	11	170	2.9e-18	61.8	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918283123	254	99.25	3	251	2	267	7.3e-62	203.8	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918283124	125	87.67	1	65	6	69	5.6e-16	52.8	COG1146	NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit	68
2918283125	194	93.14	1	183	5	194	8.5e-28	91.8	COG1014	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, gamma subunit	203
2918283126	88	39.73	2	39	38	66	1.3e-11	22.4	COG1146	NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit	68
2918283126	88	84.93	10	74	5	66	1.3e-11	27.8	COG1146	NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit	68
2918283127	358	86.65	1	331	5	335	2.5e-59	193.2	COG0674	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, alpha subunit	365
2918283128	267	68.23	16	260	12	215	9.9e-45	147.5	COG1013	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, beta subunit	294
2918283129	505	96.83	1	504	7	556	1.1e-83	276	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2918283130	412	95.36	11	394	5	353	3.4e-36	119.5	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918283131	287	96.01	1	287	8	296	6.7e-59	194.4	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2918283132	340	97.21	1	314	7	320	1.2e-68	226.3	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918283133	257	99.21	1	252	3	254	4.4e-83	273	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2918283134	234	99.16	1	234	3	237	1.4e-74	244.8	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2918283135	256	98.88	1	253	4	268	1.0e-59	196.6	COG1018	Ferredoxin-NADP reductase	266
2918283136	267	98.87	3	264	4	265	1.5e-69	228.9	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918283138	297	83.49	1	296	2	269	7.1e-21	69.7	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2918283139	293	99.25	2	258	2	267	1.0e-66	219.8	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918283140	402	94.15	7	393	4	373	3.4e-70	232	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2918283141	162	81.95	13	150	21	129	3.1e-21	70.2	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918283142	220	96.74	1	220	3	210	5.6e-47	155	COG0625	Glutathione S-transferase	211
2918283143	347	96.87	1	347	9	348	0.0e+00	465.7	COG3435	Gentisate 1,2-dioxygenase	351
2918283144	239	78.75	5	232	57	271	1.4e-74	245.6	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
2918283145	263	98.51	4	260	3	266	1.7e-60	199.4	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918283146	369	98.39	1	365	1	367	1.4e-69	229.2	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
2918283147	341	87.38	62	332	1	263	3.7e-31	103.4	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
2918283148	559	96.51	2	557	13	537	2.0e-104	344.3	COG1178	ABC-type Fe3+ transport system, permease component	540
2918283149	77	92.75	1	68	1	64	4.9e-17	56	COG1942	Phenylpyruvate tautomerase PptA, 4-oxalocrotonate tautomerase family	69
2918283150	356	98.3	1	356	6	352	8.9e-114	375	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
2918283151	565	98.05	1	565	11	564	7.1e-80	255.8	COG2936	Predicted acyl esterase	563
2918283153	147	47.74	25	143	102	196	1.1e-27	91.7	COG3544	Uncharacterized conserved protein, DUF305 family	190
2918283155	549	54.92	127	464	96	257	1.1e-03	10.3	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918283156	538	95.85	2	537	17	570	1.6e-124	411.3	COG0747	ABC-type transport system, periplasmic component	556
2918283157	769	90.36	323	760	35	390	3.9e-45	149.9	COG0642	Signal transduction histidine kinase	336
2918283158	313	97.34	2	295	3	295	1.8e-45	150.1	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918283159	314	98.99	7	309	3	297	1.1e-113	374	COG3246	Uncharacterized conserved protein, DUF849 family	298
2918283160	513	96.04	1	513	2	534	1.5e-91	300.5	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
2918283161	349	85.88	2	349	20	317	5.2e-88	289.8	COG0123	Acetoin utilization deacetylase AcuC or a related deacetylase	340
2918283162	409	98.8	7	408	2	414	1.9e-54	179.7	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
2918283163	328	99.03	1	318	1	306	1.7e-44	145.7	COG1893	Ketopantoate reductase	307
2918283164	563	98.73	8	544	4	548	0.0e+00	678	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
2918283165	290	95.64	2	287	13	297	1.6e-95	314	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2918283166	326	98.74	4	325	3	316	1.3e-114	377.3	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2918283167	530	95.33	1	528	16	566	6.7e-112	369.8	COG0747	ABC-type transport system, periplasmic component	556
2918283168	436	98.33	17	432	7	417	2.0e-81	268.7	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
2918283169	337	98.67	18	317	1	297	7.3e-53	174.7	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918283170	317	98.67	14	315	2	298	4.2e-48	159.2	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918283171	281	97.44	10	281	5	270	1.7e-88	291.3	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
2918283172	250	99.25	4	248	2	267	1.6e-70	232.2	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918283173	459	53.26	247	456	4	207	5.7e-26	16.1	COG0477	MFS family permease	338
2918283173	459	73.63	24	284	6	287	5.7e-26	73.1	COG0477	MFS family permease	338
2918283174	392	90.35	36	392	30	366	2.6e-87	287.5	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
2918283175	228	93.78	1	216	1	196	5.4e-36	118.7	COG0406	Broad specificity phosphatase PhoE	208
2918283176	253	98.88	1	249	2	266	7.5e-58	190.8	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918283177	236	94.91	13	234	7	211	4.7e-36	119	COG0778	Nitroreductase	207
2918283178	254	91.29	9	238	9	228	3.9e-50	164.9	COG2186	DNA-binding transcriptional regulator, FadR family	241
2918283179	537	98.19	14	537	1	542	0.0e+00	563.2	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
2918283180	398	98.25	4	398	8	401	0.0e+00	459.9	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2918283181	261	99.25	12	260	2	267	7.1e-79	259.7	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918283182	393	99	1	393	1	395	4.3e-95	313.7	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918283183	356	94.19	9	343	5	312	5.2e-61	201.1	COG3173	Predicted  kinase, aminoglycoside phosphotransferase (APT) family	321
2918283184	387	98.73	4	386	6	394	1.1e-77	256.2	COG0183	Acetyl-CoA acetyltransferase	392
2918283185	259	99.62	1	256	2	265	7.6e-83	272.5	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918283186	401	96.99	9	378	8	362	6.1e-35	115.3	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918283187	30	11.02	2	30	2	29	2.3e-05	18.5	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2918283188	1363	44.21	1251	1360	91	174	4.2e-21	28.3	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
2918283188	1363	45.79	962	1084	67	153	4.2e-21	20.8	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
2918283188	1363	49.47	710	838	56	149	4.2e-21	20.2	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
2918283188	1363	94.57	48	543	22	543	1.3e-78	257.2	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
2918283189	282	47.91	1	276	2	173	6.2e-14	47.5	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
2918283191	367	80.68	11	354	77	406	5.5e-19	63.8	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918283193	156	52.41	33	152	53	139	8.1e-11	36.8	COG3495	Uncharacterized protein	166
2918283194	119	88.98	14	117	4	108	1.9e-15	51.8	COG0640	DNA-binding transcriptional regulator, ArsR family	110
2918283195	274	96.69	1	266	7	269	3.5e-90	296.5	COG3741	N-formylglutamate amidohydrolase	272
2918283196	136	88.19	2	134	3	129	1.1e-26	87.9	COG2703	Hemerythrin	144
2918283197	261	97.3	8	261	3	254	7.9e-98	321.5	COG0623	Enoyl-[acyl-carrier-protein] reductase (NADH)	259
2918283199	291	62.5	95	161	16	70	1.1e-03	13	COG1873	Sporulation protein YlmC, PRC-barrel domain family	87
2918283200	213	94.44	6	209	8	194	6.4e-77	252	COG0378	Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase	202
2918283201	268	98.69	40	268	4	229	3.3e-64	211.6	COG0830	Urease accessory protein UreF	229
2918283202	161	89.74	5	160	15	154	1.4e-40	133	COG2371	Urease accessory protein UreE	155
2918283203	281	94.03	1	280	8	259	1.6e-69	228.6	COG0796	Glutamate racemase	269
2918283204	569	99.82	2	569	2	569	0.0e+00	1079.2	COG0804	Urease alpha subunit	568
2918283206	101	95.28	1	101	1	101	5.9e-49	159.2	COG0832	Urease beta subunit	106
2918283207	100	100	1	100	1	100	3.7e-53	172.5	COG0831	Urease gamma subunit	100
2918283208	280	98.16	7	278	6	272	2.1e-63	208.9	COG0829	Urease accessory protein UreH	269
2918283209	780	98.08	5	779	14	779	0.0e+00	1194.4	COG4631	Xanthine dehydrogenase, molybdopterin-binding subunit B	781
2918283210	489	96.55	1	488	8	483	0.0e+00	668	COG4630	Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A	493
2918283212	260	95.74	1	254	10	256	5.6e-74	243.4	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2918283213	261	97.21	2	259	3	246	1.6e-85	281.1	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2918283214	350	94.33	9	349	10	325	3.2e-43	142.7	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918283215	144	92.02	4	122	12	161	1.2e-30	101.4	COG0517	CBS domain	117
2918283216	233	98.1	19	229	2	208	3.2e-51	168.3	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918283217	219	98.58	4	214	2	209	1.3e-44	146.7	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918283218	512	25.21	407	512	267	358	2.4e-126	14.7	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
2918283218	512	90.14	13	399	30	358	2.4e-126	407.5	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
2918283219	853	69.54	433	851	118	391	5.8e-50	165.8	COG0642	Signal transduction histidine kinase	336
2918283220	141	86.96	1	141	13	152	1.7e-48	159.1	COG1238	Uncharacterized membrane protein YqaA, SNARE-associated domain	161
2918283221	148	98.32	18	135	2	118	2.0e-33	109.5	COG2832	Uncharacterized membrane protein YbaN, DUF454 family	119
2918283222	486	97.48	23	464	2	388	2.3e-105	347.1	COG0348	Polyferredoxin	386
2918283223	182	95.29	3	172	5	166	3.9e-59	193.4	COG0521	Molybdopterin biosynthesis enzyme MoaB	169
2918283225	304	91.91	13	302	25	308	3.9e-69	227.5	COG3386	Sugar lactone lactonase YvrE	307
2918283226	514	98.81	1	503	1	498	0.0e+00	567.1	COG3333	TctA family transporter	504
2918283228	322	98.43	5	322	5	318	5.2e-94	309.4	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918283229	216	95.73	6	215	6	207	2.8e-61	201	COG0800	2-keto-3-deoxy-6-phosphogluconate aldolase	211
2918283230	345	94.44	12	335	4	292	1.9e-77	254.6	COG3734	2-keto-3-deoxy-galactonokinase	306
2918283231	269	100	22	267	1	246	3.2e-68	223.9	COG1414	DNA-binding transcriptional regulator, IclR family	246
2918283232	258	99.25	3	256	2	267	8.6e-59	193.8	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918283233	562	97.17	53	514	10	421	1.6e-84	278.8	COG1055	Na+/H+ antiporter NhaD or related arsenite permease	424
2918283234	186	39.95	4	171	6	162	3.1e-31	102.7	COG5659	SRSO17 transposase	385
2918283236	439	99.47	52	435	2	378	1.1e-118	390.6	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
2918283237	187	90.4	2	177	8	167	2.6e-33	109.3	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
2918283238	339	98.19	6	339	5	330	1.6e-68	225.8	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
2918283239	163	78.45	2	163	36	177	4.1e-29	96	COG5342	Invasion protein IalB, involved in pathogenesis	181
2918283240	1410	93.57	744	1410	39	591	3.1e-48	159.5	COG4625	Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain	577
2918283241	88	33.33	1	87	53	124	2.1e-20	67.1	COG3316	Transposase (or an inactivated derivative)	215
2918283244	290	16.54	231	290	169	211	4.3e-28	11.5	COG5010	Flp pilus assembly protein TadD, contains TPR repeats	257
2918283244	290	86.54	1	237	11	235	4.3e-28	86	COG5010	Flp pilus assembly protein TadD, contains TPR repeats	257
2918283246	438	91.39	2	437	35	480	6.0e-127	418	COG4964	Flp pilus assembly protein, secretin CpaC	455
2918283248	66	94.83	8	65	2	56	3.5e-11	37.4	COG3847	Flp pilus assembly protein, pilin Flp	58
2918283249	326	82.97	1	254	1	229	6.7e-63	206.8	COG3745	Flp pilus assembly protein CpaB	276
2918283250	499	52.04	1	198	13	114	5.9e-06	21	COG4961	Flp pilus assembly protein TadG	185
2918283251	162	46.43	1	149	4	94	1.2e-12	41.4	COG4961	Flp pilus assembly protein TadG	185
2918283253	407	72.38	37	399	82	364	1.4e-49	163.4	COG4963	Flp pilus assembly protein, ATPase CpaE	366
2918283254	466	96.13	65	425	11	358	0.0e+00	486.8	COG4962	Pilus assembly protein, ATPase of CpaF family	355
2918283255	322	98.71	6	322	5	309	2.3e-73	241.4	COG4965	Flp pilus assembly protein TadB	309
2918283256	327	76.95	12	325	69	315	4.7e-39	128.5	COG2064	Pilus assembly protein TadC	320
2918283257	165	86.9	2	164	14	159	1.5e-21	70.8	COG4960	Flp pilus assembly protein, protease CpaA	168
2918283266	1048	31.78	290	361	28	61	7.8e-05	2.3	COG5489	Uncharacterized conserved protein, DUF736 family	107
2918283266	1048	36.45	148	218	38	76	7.8e-05	8	COG5489	Uncharacterized conserved protein, DUF736 family	107
2918283270	380	95.64	1	372	17	389	5.9e-66	217.2	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918283271	1047	99.8	1	1026	2	1013	0.0e+00	1115.3	COG0841	Multidrug efflux pump subunit AcrB	1009
2918283273	221	61.09	42	210	41	186	3.6e-09	30.4	COG0340	Biotin-(acetyl-CoA carboxylase) ligase	238
2918283276	218	91.18	9	207	10	195	7.0e-36	117.3	COG3381	Cytoplasmic chaperone TorD involved in molybdoenzyme TorA maturation	204
2918283277	66	22.22	9	59	2	27	4.8e-03	11	COG4980	Gas vesicle protein	115
2918283278	965	99.63	27	965	3	809	0.0e+00	599.6	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
2918283279	215	73.66	1	180	11	161	2.8e-44	144.4	COG0437	Fe-S-cluster-containing dehydrogenase component	203
2918283280	335	94.5	110	326	4	209	5.3e-56	183.1	COG2864	Cytochrome b subunit of formate dehydrogenase	218
2918283282	293	97.97	10	290	6	294	4.2e-48	158.4	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918283283	347	31.19	3	91	15	82	7.2e-37	13.3	COG0516	IMP dehydrogenase/GMP reductase	170
2918283283	347	93.58	134	344	3	206	7.2e-37	106.6	COG0516	IMP dehydrogenase/GMP reductase	170
2918283284	616	99.5	3	614	4	598	0.0e+00	667.9	COG0322	Excinuclease UvrABC, nuclease subunit	581
2918283286	489	97.08	57	430	2	300	4.2e-48	157.7	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
2918283287	424	72.41	1	355	6	236	3.4e-19	61.8	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
2918283289	222	41.2	1	217	262	446	3.7e-33	108.8	COG2610	H+/gluconate symporter or related permease	442
2918283290	375	92.56	4	368	23	383	2.3e-44	146	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918283291	1023	99.8	5	1009	1	1012	0.0e+00	860.2	COG0841	Multidrug efflux pump subunit AcrB	1009
2918283293	426	92.56	23	424	12	372	1.6e-45	148.3	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918283294	239	96.46	11	237	2	219	7.9e-83	271.1	COG1136	ABC-type lipoprotein export system, ATPase component	226
2918283295	401	99.8	18	401	2	510	1.9e-73	242.2	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
2918283296	544	38.48	246	435	204	355	9.2e-16	2	COG2814	Predicted arabinose efflux permease, MFS family	394
2918283296	544	45.82	16	219	12	192	9.2e-16	51.5	COG2814	Predicted arabinose efflux permease, MFS family	394
2918283297	390	92.9	39	390	17	343	5.9e-100	328.2	COG1566	Multidrug resistance efflux pump	352
2918283298	143	84.67	14	142	11	126	2.8e-36	118.4	COG1586	S-adenosylmethionine decarboxylase or arginine decarboxylase	136
2918283299	163	62.5	19	135	58	152	2.3e-13	44.2	COG0782	Transcription elongation factor, GreA/GreB family	151
2918283300	312	73.1	1	291	61	310	2.3e-35	116.3	COG0668	Small-conductance mechanosensitive channel	316
2918283302	342	61.94	224	318	43	125	1.4e-06	20.5	COG3335	Transposase	132
2918283303	254	73.75	185	253	17	75	3.4e-15	48.4	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2918283304	860	7.32	1	49	417	457	3.8e-45	20.2	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918283304	860	17.5	525	653	363	460	3.8e-45	24.3	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918283304	860	31.79	653	827	308	485	3.8e-45	76.2	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918283304	860	48.93	46	390	236	509	3.8e-45	45.1	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918283305	286	96.59	4	279	8	262	4.9e-75	246	COG3665	Uncharacterized conserved protein YcgI, DUF1989 family	264
2918283309	187	17.36	15	160	111	202	2.9e-03	10.3	COG5298	Uncharacterized protein YdaL	530
2918283311	767	95.25	1	432	18	438	0.0e+00	545	COG0281	Malic enzyme	432
2918283311	767	99.08	429	755	1	324	8.0e-114	373.6	COG0280	Phosphotransacetylase	327
2918283312	437	98.09	12	432	3	412	0.0e+00	517.7	COG1301	Na+/H+-dicarboxylate symporter	415
2918283313	580	98.84	1	577	6	602	0.0e+00	573.7	COG4191	Signal transduction histidine kinase regulating C4-dicarboxylate transport system	603
2918283314	449	98.93	1	449	3	464	0.0e+00	567.4	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2918283315	193	96.32	1	191	5	187	3.5e-30	98.9	COG3009	Uncharacterized lipoprotein YmbA	190
2918283316	563	96.56	9	563	7	540	0.0e+00	451.8	COG3008	Paraquat-inducible protein B	553
2918283317	382	87.8	1	377	48	414	2.2e-113	373.2	COG2995	Uncharacterized paraquat-inducible protein A	418
2918283320	335	98.26	1	335	5	343	3.1e-108	356.2	COG1294	Cytochrome bd-type quinol oxidase, subunit 2	346
2918283321	468	97.59	2	452	2	446	0.0e+00	540.6	COG1271	Cytochrome bd-type quinol oxidase, subunit 1	457
2918283322	297	78.01	4	287	70	335	1.0e-89	295.2	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
2918283323	489	96.01	1	485	15	495	0.0e+00	737.9	COG0753	Catalase	496
2918283324	321	97.67	6	300	2	295	1.4e-64	212.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918283325	268	96.58	7	266	3	256	4.1e-55	180.8	COG0566	tRNA G18 (ribose-2'-O)-methylase SpoU	260
2918283326	66	68.25	8	57	12	54	3.0e-09	30.4	COG5457	Uncharacterized conserved protein YjiS, DUF1127 family	63
2918283328	261	74.04	4	254	62	272	1.9e-48	159.1	COG1864	DNA/RNA endonuclease G, NUC1	281
2918283329	84	28.38	3	78	79	141	1.3e-03	12.2	COG1976	Translation initiation factor 6 (eIF-6)	222
2918283330	147	51.54	7	125	4	70	6.9e-08	27.4	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918283333	270	22.11	109	243	20	61	1.7e-06	21.5	COG3703	Cation transport regulator ChaC	190
2918283334	387	52.24	203	369	37	141	3.8e-01	3.4	COG4723	Phage-related protein, tail component	198
2918283338	57	67.16	2	56	12	56	1.8e-07	25.4	COG5481	Uncharacterized protein	67
2918283339	446	65.91	149	221	12	69	1.8e-02	9.5	COG5552	Uncharacterized protein	88
2918283341	586	52.33	4	544	35	180	1.7e-14	46.7	COG0500	SAM-dependent methyltransferase	257
2918283347	356	18.36	93	173	106	152	2.8e-03	4.6	COG5595	Predicted  nucleic acid-binding protein, contains Zn-ribbon domain	256
2918283347	356	18.36	204	344	116	162	2.8e-03	3.2	COG5595	Predicted  nucleic acid-binding protein, contains Zn-ribbon domain	256
2918283349	181	93.05	2	178	7	180	1.4e-31	103.9	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
2918283351	686	97.51	1	241	3	237	2.8e-60	197	COG1861	Spore coat polysaccharide biosynthesis protein SpsF, cytidylyltransferase family	241
2918283351	686	98.38	261	664	7	431	5.8e-105	345	COG0001	Glutamate-1-semialdehyde aminotransferase	432
2918283352	332	95.44	3	327	6	340	5.8e-47	154.6	COG0673	Predicted dehydrogenase	342
2918283354	441	96.8	11	429	11	373	7.1e-99	324.1	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
2918283355	348	94.87	15	343	5	337	1.4e-35	115.3	COG0673	Predicted dehydrogenase	342
2918283356	245	97.93	2	244	3	238	3.7e-61	200	COG1861	Spore coat polysaccharide biosynthesis protein SpsF, cytidylyltransferase family	241
2918283357	251	73.16	12	190	47	185	1.1e-32	107	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
2918283359	821	60.58	193	807	244	621	4.5e-98	322.3	COG3914	Predicted O-linked N-acetylglucosamine transferase, SPINDLY family	620
2918283360	450	62.8	4	178	40	196	1.1e-09	31.5	COG3063	Tfp pilus assembly protein PilF	250
2918283361	656	92.63	4	646	44	621	1.6e-64	211.1	COG3914	Predicted O-linked N-acetylglucosamine transferase, SPINDLY family	620
2918283362	418	86.97	20	289	22	268	8.0e-27	88	COG4584	Transposase	278
2918283364	166	85.4	14	149	10	126	1.6e-03	12.1	COG4319	Ketosteroid isomerase homolog	137
2918283365	201	96.61	1	175	2	172	1.9e-53	174.4	COG0663	Carbonic anhydrase or acetyltransferase, isoleucine patch superfamily	176
2918283366	402	99.24	3	402	2	392	4.4e-121	398.6	COG0183	Acetyl-CoA acetyltransferase	392
2918283367	156	88.05	4	152	17	156	9.2e-41	132.6	COG2030	Acyl dehydratase	159
2918283368	269	97.39	21	267	3	263	3.0e-63	207.8	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918283369	396	97.74	1	392	8	397	4.5e-75	247.2	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918283370	382	97.74	1	380	1	390	1.1e-65	216.2	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918283371	292	98.13	4	252	5	267	2.6e-54	178.4	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918283372	386	99.49	5	386	2	393	5.7e-114	375.2	COG0183	Acetyl-CoA acetyltransferase	392
2918283373	350	22.06	1	126	2	89	4.4e-36	32.2	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918283373	350	36.59	182	339	243	388	4.4e-36	90.8	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918283374	387	99	1	387	3	397	5.1e-83	273.4	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918283375	255	97.36	1	249	8	265	2.9e-66	217.5	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918283376	370	98.55	8	358	3	342	2.4e-77	254.3	COG2070	NAD(P)H-dependent flavin oxidoreductase YrpB, nitropropane dioxygenase family	336
2918283377	286	86.04	7	272	6	233	1.2e-53	175.9	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918283378	250	84.39	1	249	45	298	1.8e-39	130	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2918283379	603	96.28	28	338	10	320	7.8e-43	140.6	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918283379	603	97.64	367	600	6	253	3.4e-67	207.1	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2918283380	239	96.62	1	232	3	231	1.0e-75	247.9	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2918283383	1956	31.61	1771	1946	324	500	8.1e-27	73.2	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918283383	1956	55.18	1364	1846	147	455	8.1e-27	31.3	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918283384	336	75	186	321	27	125	1.4e-15	50.5	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918283385	305	98.01	3	301	4	298	8.4e-51	167.4	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918283386	350	93.73	8	346	10	323	4.9e-43	141.4	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918283387	263	99.25	3	262	2	267	9.8e-59	193.1	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918283388	293	95.62	27	287	3	242	9.6e-85	277.9	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2918283389	257	94.96	1	252	12	256	4.3e-71	233.4	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2918283390	348	89.55	1	343	7	306	2.7e-45	148.8	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918283391	488	93.4	4	457	23	418	5.4e-57	186.8	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
2918283392	315	95.53	6	314	7	305	1.0e-87	287.9	COG2421	Acetamidase/formamidase	305
2918283394	486	98.38	8	444	2	425	0.0e+00	445.6	COG0044	Dihydroorotase or related cyclic amidohydrolase	430
2918283399	981	49.6	875	976	28	89	4.7e-06	21.1	COG2198	HPt (histidine-containing phosphotransfer) domain	122
2918283399	981	85.53	322	714	56	392	3.1e-79	261.4	COG0642	Signal transduction histidine kinase	336
2918283399	981	93.23	724	854	5	128	5.2e-37	118.3	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918283400	241	98.71	8	237	2	230	7.7e-73	238.6	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918283401	335	88.07	12	318	31	318	5.1e-38	124.5	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
2918283402	888	99.75	2	784	1	808	0.0e+00	464.7	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
2918283403	337	99.69	10	337	2	325	3.2e-116	381.7	COG2896	Molybdenum cofactor biosynthesis enzyme MoaA	322
2918283404	73	52.13	1	69	1	49	2.1e-17	57.6	COG1826	Sec-independent protein translocase protein TatA	94
2918283406	204	95.69	1	204	7	206	4.0e-70	229.6	COG2860	Uncharacterized membrane protein YeiH	209
2918283407	37	13.03	2	37	192	222	8.5e-04	13.1	COG3473	Maleate cis-trans isomerase	238
2918283414	140	98.48	4	136	2	131	8.6e-40	130.2	COG1487	Predicted nucleic acid-binding protein, contains PIN domain	133
2918283415	74	97.33	3	74	2	74	9.4e-22	70.7	COG4456	Virulence-associated protein VagC (function unknown)	74
2918283419	43	25.84	1	41	17	39	1.3e-04	16.8	COG3609	Transcriptional regulator, contains Arc/MetJ-type RHH (ribbon-helix-helix) DNA-binding domain	89
2918283420	31	12.5	2	31	23	49	4.1e-08	27.1	COG3316	Transposase (or an inactivated derivative)	215
2918283421	302	97.34	6	302	1	293	1.9e-49	163	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918283422	220	67.92	1	197	5	184	1.6e-26	87	COG0300	Short-chain dehydrogenase	265
2918283424	228	88.89	2	212	10	201	1.5e-38	126.3	COG3316	Transposase (or an inactivated derivative)	215
2918283426	93	84.16	5	93	4	88	1.1e-31	102.9	COG4327	Uncharacterized membrane protein	101
2918283427	587	98.69	1	581	7	535	0.0e+00	604.6	COG4147	Na+(or H+)/acetate symporter ActP	529
2918283428	620	99.34	4	618	3	608	0.0e+00	541.1	COG2905	Signal-transduction protein containing cAMP-binding, CBS, and nucleotidyltransferase domains	610
2918283431	333	96.3	102	322	7	214	1.2e-55	182.2	COG3316	Transposase (or an inactivated derivative)	215
2918283435	433	93.33	3	431	12	375	3.5e-34	112.1	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918283436	409	99.8	31	409	2	510	7.1e-59	193.8	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
2918283437	515	15.87	37	133	245	317	1.4e-47	10.7	COG1538	Outer membrane protein TolC	457
2918283437	515	89.57	57	508	45	456	1.4e-47	153.5	COG1538	Outer membrane protein TolC	457
2918283439	110	19.44	5	55	7	48	1.6e-14	40.5	COG3316	Transposase (or an inactivated derivative)	215
2918283439	110	22.69	49	95	166	214	1.6e-14	9.5	COG3316	Transposase (or an inactivated derivative)	215
2918283440	167	7.59	12	39	34	51	9.3e-09	5.6	COG1122	Energy-coupling factor transporter ATP-binding protein EcfA2	235
2918283440	167	27.85	37	127	162	227	9.3e-09	22.3	COG1122	Energy-coupling factor transporter ATP-binding protein EcfA2	235
2918283441	245	99.14	10	243	2	231	2.3e-62	204.3	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918283442	939	53.6	829	923	28	94	7.3e-05	15.8	COG2198	HPt (histidine-containing phosphotransfer) domain	122
2918283442	939	91.12	234	677	33	391	6.7e-70	229.7	COG0642	Signal transduction histidine kinase	336
2918283442	939	93.23	687	817	6	129	3.9e-35	113.4	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918283444	264	63.89	11	264	4	256	4.5e-100	329.1	COG3328	Transposase (or an inactivated derivative)	379
2918283449	1193	38.65	653	887	86	182	3.5e-11	36.2	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2918283455	710	57.53	2	565	57	560	0.0e+00	438.1	COG4096	Type I site-specific restriction endonuclease, part of a restriction-modification system	875
2918283456	540	68.83	133	540	158	517	6.5e-59	193.5	COG0286	Type I restriction-modification system, DNA methylase subunit	489
2918283457	410	17.78	63	170	299	370	2.4e-23	38.3	COG0732	Restriction endonuclease S subunit	391
2918283457	410	36.54	200	390	227	374	2.4e-23	36.3	COG0732	Restriction endonuclease S subunit	391
2918283458	309	99.35	1	309	1	306	4.9e-94	309.2	COG1715	Restriction endonuclease Mrr	308
2918283459	189	57.01	1	189	135	325	7.9e-26	85.5	COG0582	Integrase	309
2918283466	297	98.34	4	297	1	296	4.4e-43	142.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918283468	480	49.09	271	477	8	195	7.2e-43	31.1	COG0477	MFS family permease	338
2918283468	480	81.98	17	301	5	318	7.2e-43	114.1	COG0477	MFS family permease	338
2918283470	735	84.47	286	730	65	423	1.4e-55	183.4	COG0840	Methyl-accepting chemotaxis protein	408
2918283471	305	97.01	7	302	5	296	1.3e-38	126.8	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918283472	181	57.66	10	109	7	85	5.4e-04	13.7	COG4319	Ketosteroid isomerase homolog	137
2918283475	323	68.99	18	137	29	117	2.3e-10	33.8	COG3677	Transposase	129
2918283478	355	78.68	1	199	1	155	3.0e-16	51.3	COG1988	Membrane-bound metal-dependent hydrolase YbcI, DUF457 family	190
2918283480	244	32	34	113	64	103	1.5e-05	11.6	COG3293	Transposase	124
2918283480	244	33.6	190	233	83	124	1.5e-05	9.2	COG3293	Transposase	124
2918283483	528	97.55	99	262	4	162	1.3e-49	162.1	COG3436	Transposase	157
2918283484	117	63.8	5	117	41	144	1.7e-29	96.5	COG3436	Transposase	157
2918283485	136	62.39	12	133	5	77	5.0e-18	59.5	COG2963	Transposase and inactivated derivatives	116
2918283488	47	21.3	1	47	13	58	7.0e-15	49.2	COG3316	Transposase (or an inactivated derivative)	215
2918283489	105	17.01	5	88	272	328	5.9e-04	13.8	COG0582	Integrase	309
2918283490	193	36.12	2	152	94	214	8.6e-12	39.4	COG0582	Integrase	309
2918283492	61	23.15	2	61	7	56	1.2e-17	58.3	COG3316	Transposase (or an inactivated derivative)	215
2918283493	338	8.21	237	295	194	231	6.6e-15	13.4	COG0076	Glutamate or tyrosine decarboxylase or a related PLP-dependent protein	460
2918283493	338	26.13	31	214	59	179	6.6e-15	30.4	COG0076	Glutamate or tyrosine decarboxylase or a related PLP-dependent protein	460
2918283494	382	82.19	1	375	53	375	1.2e-114	377	COG5659	SRSO17 transposase	385
2918283496	406	98.48	11	402	6	395	0.0e+00	489.3	COG3328	Transposase (or an inactivated derivative)	379
2918283497	312	96.02	13	246	2	218	1.1e-24	81.2	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
2918283500	100	57.06	1	98	29	121	2.3e-22	73.3	COG3436	Transposase	157
2918283501	138	96.58	11	129	2	114	1.7e-18	60.9	COG2963	Transposase and inactivated derivatives	116
2918283502	295	96.36	4	233	8	219	1.7e-50	165.1	COG1788	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit	220
2918283505	217	75.37	81	202	3	103	1.5e-15	49.1	COG3335	Transposase	132
2918283506	119	85.61	1	119	1	119	3.8e-20	66	COG3415	Transposase	138
2918283508	240	99.58	9	240	2	237	3.5e-86	282.2	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2918283509	56	18.5	1	47	208	254	1.4e-16	54.5	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
