gene_oid	gene_length	percent_identity	query_start	query_end	subj_start	subj_end	evalue	bit_score	cog_id	cog_name	cog_length
648912359	267	44.32	2	265	1	254	1.0e-66	246	COG4105	Outer membrane protein assembly factor BamD, BamD/ComL family	254
648912360	373	49.66	28	322	2	289	6.0e-86	311	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
648912361	257	47.79	15	256	1	249	2.0e-74	272	COG1496	Copper oxidase (laccase) domain	249
648912362	563	18.55	9	557	1	459	6.0e-52	198	COG0277	FAD/FMN-containing dehydrogenase	459
648912364	196	31.07	19	190	1	177	5.0e-21	94.5	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
648912365	362	22.4	4	358	10	384	7.0e-30	124	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
648912369	259	61.09	1	257	1	253	7.0e-94	337	COG3022	Cytoplasmic iron level regulating protein YaaA, DUF328/UPF0246 family	253
648912370	396	33.17	4	393	3	388	1.0e-76	280	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
648912372	129	54.69	1	127	2	128	9.0e-31	125	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
648912373	391	45.18	5	391	21	410	1.0e-115	410	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
648912374	197	45.41	3	197	2	193	3.0e-61	227	COG0127	Inosine/xanthosine triphosphate pyrophosphatase, all-alpha NTP-PPase family	194
648912376	377	29.74	1	377	2	342	2.0e-71	262	COG3317	Uncharacterized lipoprotein	342
648912377	291	51.54	1	291	4	296	3.0e-93	335	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
648912378	463	44.3	13	452	4	440	2.0e-95	343	COG2233	Xanthine/uracil permease	451
648912379	389	35.42	1	388	1	414	2.0e-113	402	COG1004	UDP-glucose 6-dehydrogenase	414
648912381	619	41.15	98	617	55	564	5.0e-113	402	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
648912382	396	28.27	12	385	9	373	4.0e-35	142	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
648912383	411	28.42	122	408	98	381	5.0e-34	138	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
648912384	396	36.69	8	390	6	389	4.0e-94	338	COG4671	Predicted glycosyl transferase	400
648912385	376	21.08	1	376	1	354	1.0e-19	90.8	COG3203	Outer membrane protein (porin)	354
648912387	593	21.06	83	590	149	699	7.0e-38	152	COG1328	Anaerobic ribonucleoside-triphosphate reductase	700
648912390	150	53.02	3	150	2	148	2.0e-49	188	COG0756	dUTPase	148
648912391	210	56.4	2	210	4	214	2.0e-79	288	COG0259	Pyridoxine/pyridoxamine 5'-phosphate oxidase	214
648912392	348	43.82	95	338	1	247	5.0e-61	228	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
648912393	633	65.1	144	608	1	432	0.0e+00	750	COG0422	Thiamine biosynthesis protein ThiC	432
648912394	249	48.15	2	243	19	257	2.0e-70	258	COG0566	tRNA G18 (ribose-2'-O)-methylase SpoU	260
648912395	247	42.35	1	247	4	257	7.0e-50	190	COG0725	ABC-type molybdate transport system, periplasmic component	258
648912396	264	54.26	38	260	1	223	9.0e-64	236	COG4149	ABC-type molybdate transport system, permease component	225
648912398	375	66.49	7	375	2	374	0.0e+00	582	COG5008	Tfp pilus assembly protein, ATPase PilU	375
648912399	233	51.08	5	233	4	233	3.0e-60	224	COG0775	Nucleoside phosphorylase	234
648912400	597	71.24	1	597	6	603	0.0e+00	1060	COG0481	Translation elongation factor EF-4, membrane-bound GTPase	603
648912403	957	68.8	12	950	3	935	0.0e+00	1587	COG0178	Excinuclease UvrABC ATPase subunit	935
648912405	350	57.02	1	349	1	363	0.0e+00	482	COG4174	ABC-type microcin C transport system, permease component YejB	364
648912406	348	54.71	18	346	12	339	2.0e-116	411	COG4239	ABC-type microcin C transport system, permease component YejE	341
648912407	513	52.76	1	509	4	528	0.0e+00	641	COG4172	ABC-type microcin C transport system, duplicated ATPase component YejF	534
648912409	432	29.51	7	432	4	415	3.0e-65	242	COG2733	Uncharacterized membrane-anchored protein YjiN, DUF445 family	415
648912410	91	37.78	1	90	24	113	2.0e-18	84.2	COG2919	Cell division protein FtsB	117
648912411	428	68.31	1	426	1	423	0.0e+00	669	COG0148	Enolase	423
648912412	487	30.32	257	477	1	170	8.0e-36	144	COG0516	IMP dehydrogenase/GMP reductase	170
648912414	444	53.39	1	442	1	436	0.0e+00	530	COG2704	Anaerobic C4-dicarboxylate transporter	436
648912416	120	36.61	10	120	15	124	1.0e-18	85.3	COG3671	Uncharacterized membrane protein	125
648912417	161	39.86	9	150	2	144	7.0e-34	136	COG2606	Cys-tRNA(Pro) deacylase, prolyl-tRNA editing enzyme YbaK/EbsC	155
648912418	117	37.5	1	114	8	127	1.0e-24	104	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
648912419	300	33.11	10	298	10	298	9.0e-55	207	COG0354	Folate-binding Fe-S cluster repair protein YgfZ, possible role in tRNA modification	305
648912420	335	26.3	20	273	1	240	4.0e-23	102	COG2890	Methylase of polypeptide chain release factors	280
648912422	597	52.53	85	497	1	409	3.0e-128	452	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
648912425	352	53.64	8	349	4	344	6.0e-124	437	COG1613	ABC-type sulfate transport system, periplasmic component	348
648912426	398	55.92	4	397	1	394	0.0e+00	549	COG0282	Acetate kinase	396
648912428	63	48.21	1	56	1	56	2.0e-14	70.3	COG3197	Uncharacterized protein, possibly involved in nitrogen fixation	58
648912431	116	41.88	1	116	2	117	4.0e-34	136	COG3215	Tfp pilus assembly protein PilZ	117
648912432	257	48.44	1	252	1	256	2.0e-80	292	COG0084	Tat protein secretion system quality control protein TatD (DNase activity)	256
648912433	103	45.57	22	99	1	79	3.0e-17	80.1	COG3042	Putative hemolysin	85
648912434	224	47.3	4	218	3	219	4.0e-37	148	COG2836	Sulfite exporter TauE/SafE	232
648912435	268	27.57	1	266	1	253	5.0e-14	72	COG0730	Uncharacterized membrane protein YfcA	258
648912436	249	41.18	12	247	1	234	2.0e-48	185	COG1183	Phosphatidylserine synthase	234
648912437	169	47.37	1	169	1	157	1.0e-48	185	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
648912438	471	30.42	30	471	6	457	4.0e-61	229	COG0471	Di- and tricarboxylate transporter	461
648912439	333	61.11	11	333	8	329	0.0e+00	511	COG0113	Delta-aminolevulinic acid dehydratase, porphobilinogen synthase	330
648912441	167	37.95	2	165	1	166	3.0e-21	94.6	COG1076	DnaJ-domain-containing proteins 1	174
648912442	106	54.21	1	106	4	110	2.0e-37	146	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
648912444	128	51.03	1	126	5	146	2.0e-36	144	COG0822	NifU homolog involved in Fe-S cluster formation	150
648912446	404	61.95	5	388	1	386	0.0e+00	564	COG1104	Cysteine sulfinate desulfinase/cysteine desulfurase or related enzyme	386
648912447	148	37.06	1	142	1	143	6.0e-36	143	COG1959	DNA-binding transcriptional regulator, IscR family	150
648912448	390	43.78	11	380	1	348	1.0e-112	400	COG1304	FMN-dependent dehydrogenase, includes L-lactate dehydrogenase and type II isopentenyl diphosphate isomerase	360
648912449	383	38.71	4	369	3	371	2.0e-77	283	COG3705	ATP phosphoribosyltransferase regulatory subunit HisZ	390
648912450	434	61.86	5	434	2	430	0.0e+00	651	COG0104	Adenylosuccinate synthase	430
648912451	761	64.71	11	759	10	754	0.0e+00	1088	COG1882	Pyruvate-formate lyase	755
648912452	253	33.74	9	253	18	257	4.0e-61	228	COG1180	Pyruvate-formate lyase-activating enzyme	260
648912453	658	17.19	1	658	3	699	5.0e-26	113	COG4771	Outer membrane receptor for ferrienterochelin and colicins	699
648912454	357	51.27	1	350	1	345	3.0e-118	418	COG1118	ABC-type sulfate/molybdate transport systems, ATPase component	345
648912455	286	66.55	1	284	4	287	2.0e-109	388	COG4208	ABC-type sulfate transport system, permease component	287
648912456	278	53.68	4	275	3	274	5.0e-71	261	COG0555	ABC-type sulfate transport system, permease component	274
648912457	502	41.48	5	493	1	492	1.0e-127	450	COG0248	Exopolyphosphatase/pppGpp-phosphohydrolase	492
648912458	209	25.66	4	208	35	260	4.0e-14	71.3	COG0741	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)	296
648912459	464	21.7	36	395	30	383	1.0e-22	101	COG2814	Predicted arabinose efflux permease, MFS family	394
648912460	176	35.91	1	176	1	167	1.0e-35	142	COG0629	Single-stranded DNA-binding protein	167
648912461	249	39.41	48	247	53	250	6.0e-37	147	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
648912462	279	41.04	17	278	4	266	2.0e-70	259	COG3384	Aromatic ring-opening dioxygenase, catalytic subunit, LigB family	268
648912464	99	39.74	22	99	1	74	6.0e-12	62.3	COG4456	Virulence-associated protein VagC (function unknown)	74
648912465	1660	20.44	854	1618	64	726	8.0e-26	113	COG1112	Superfamily I DNA and/or RNA helicase	767
648912467	158	54.9	6	158	1	151	3.0e-39	154	COG0782	Transcription elongation factor, GreA/GreB family	151
648912468	94	47.19	5	93	1	89	1.0e-24	104	COG1534	RNA-binding protein YhbY	97
648912469	206	55.94	5	206	1	202	1.0e-73	269	COG0293	23S rRNA U2552 (ribose-2'-O)-methylase RlmE/FtsJ	205
648912470	653	60.13	9	607	1	596	0.0e+00	769	COG0465	ATP-dependent Zn proteases	596
648912472	378	50	10	374	2	364	0.0e+00	463	COG0026	Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)	375
648912474	491	47.49	19	490	1	462	0.0e+00	507	COG0147	Anthranilate/para-aminobenzoate synthases component I	462
648912476	259	30.05	5	187	9	195	2.0e-20	93	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
648912477	204	33.5	9	202	1	184	4.0e-34	137	COG2840	DNA-nicking endonuclease, Smr domain	184
648912478	887	69.33	1	883	2	883	0.0e+00	1411	COG2609	Pyruvate dehydrogenase complex, dehydrogenase (E1) component	887
648912479	533	44.16	109	533	1	403	2.0e-100	359	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
648912480	595	50.75	118	579	4	454	0.0e+00	481	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
648912481	306	31.05	61	302	42	285	3.0e-43	169	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
648912482	431	48.29	2	430	1	429	0.0e+00	476	COG0124	Histidyl-tRNA synthetase	429
648912483	209	34.78	1	207	1	204	8.0e-36	143	COG2976	Putative negative regulator of RcsB-dependent stress response	207
648912484	492	48.08	8	446	2	444	0.0e+00	560	COG1160	Predicted GTPases	444
648912485	96	72.37	3	78	2	77	2.0e-25	107	COG1923	sRNA-binding regulator protein Hfq	77
648912487	123	43.2	1	121	1	124	4.0e-20	90.3	COG3094	Uncharacterized membrane protein SirB2	129
648912488	165	50	1	158	1	158	2.0e-50	191	COG0801	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase	160
648912489	212	27	4	194	5	204	1.0e-24	106	COG1428	Deoxyadenosine/deoxycytidine kinase	216
648912490	154	51.97	8	152	1	152	2.0e-47	181	COG1225	Peroxiredoxin	157
648912491	292	50.84	1	291	3	299	2.0e-96	345	COG4974	Site-specific recombinase XerD	300
648912492	172	49.28	31	99	1	69	5.0e-14	70.7	COG3585	Molybdopterin-binding protein	69
648912493	68	44.9	1	49	1	49	2.0e-08	50.7	COG2906	Bacterioferritin-associated ferredoxin	63
648912495	445	49.42	11	443	3	431	7.0e-111	394	COG1114	Branched-chain amino acid permeases	431
648912497	287	50.53	1	285	1	279	1.0e-93	336	COG1091	dTDP-4-dehydrorhamnose reductase	281
648912500	287	36.04	6	285	4	246	1.0e-70	260	COG0152	Phosphoribosylaminoimidazole-succinocarboxamide synthase	247
648912501	705	66.14	1	696	1	692	0.0e+00	1005	COG1185	Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase)	692
648912503	234	31.58	10	234	2	214	1.0e-42	166	COG2932	Phage repressor protein C, contains Cro/C1-type HTH and peptisase s24 domains	214
648912504	87	63.1	1	84	1	82	4.0e-27	112	COG3423	Predicted transcriptional regulator, lambda repressor-like DNA-binding domain	82
648912506	304	45.18	1	300	7	297	3.0e-83	301	COG2842	Bacteriophage DNA transposition protein, AAA+ family ATPase	297
648912519	91	61.54	1	91	2	92	5.0e-28	116	COG0776	Bacterial nucleoid DNA-binding protein	94
648912520	159	47.53	1	159	1	161	3.0e-44	170	COG4382	Mu-like prophage protein gp16	170
648912523	181	25.65	1	179	41	231	2.0e-20	92.4	COG0860	N-acetylmuramoyl-L-alanine amidase	231
648912528	56	55.36	1	56	3	58	9.0e-17	78.4	COG3422	Uncharacterized conserved protein YegP, UPF0339 family	59
648912535	519	61	5	519	1	515	0.0e+00	782	COG4383	Mu-like prophage protein gp29	517
648912537	165	44.85	1	164	1	140	3.0e-42	164	COG5005	Mu-like prophage protein gpG	140
648912538	354	71.79	1	354	1	353	7.0e-110	390	COG4388	Mu-like prophage I protein	357
648912539	300	65.47	1	299	2	308	0.0e+00	529	COG4397	Mu-like prophage major head subunit gpT	308
648912541	141	52.48	1	141	1	137	8.0e-51	192	COG4387	Mu-like prophage protein gp36	139
648912542	222	44.37	1	147	1	151	5.0e-52	197	COG5003	Mu-like prophage protein gp37	151
648912544	475	52.86	4	475	1	487	0.0e+00	580	COG4386	Mu-like prophage tail sheath protein gpL	487
648912549	455	33.55	3	455	5	451	0.0e+00	476	COG4228	Mu-like prophage DNA circulation protein	451
648912550	209	52.71	1	202	1	203	8.0e-68	249	COG4384	Mu-like prophage protein gp45	203
648912551	117	46.27	1	117	2	135	2.0e-33	134	COG4381	Mu-like prophage protein gp46	135
648912553	188	40	1	186	1	188	2.0e-62	232	COG3778	Uncharacterized protein YmfQ in lambdoid prophage, DUF2313 family	188
648912558	252	53.44	1	241	1	247	8.0e-87	313	COG0496	Broad specificity polyphosphatase and 5'/3'-nucleotidase SurE	252
648912562	351	25	4	271	19	271	3.0e-21	96.6	COG1566	Multidrug resistance efflux pump	352
648912563	241	18.52	1	238	3	202	2.0e-15	76.2	COG0778	Nitroreductase	207
648912564	189	28.57	1	186	1	181	3.0e-22	98.4	COG2249	Putative NADPH-quinone reductase (modulator of drug activity B)	189
648912567	248	26.07	1	245	2	278	4.0e-13	68.6	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
648912568	201	46.34	1	201	3	207	4.0e-57	214	COG4832	Uncharacterized protein	207
648912569	940	27.22	1	505	3	532	2.0e-70	261	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
648912570	116	34.19	1	115	1	103	8.0e-16	75.7	COG2315	Predicted DNA-binding protein with ?double-wing? structural motif, MmcQ/YjbR family	118
648912571	230	55.65	1	230	1	230	2.0e-80	291	COG1794	Aspartate/glutamate racemase	230
648912572	370	22.9	73	368	4	285	1.0e-15	77.6	COG0842	ABC-type multidrug transport system, permease component	286
648912573	471	29.57	1	470	2	448	1.0e-46	181	COG1538	Outer membrane protein TolC	457
648912574	759	35.52	43	753	1	654	0.0e+00	598	COG0209	Ribonucleotide reductase alpha subunit	696
648912576	384	37.07	10	380	2	347	5.0e-91	328	COG0208	Ribonucleotide reductase beta subunit, ferritin-like domain	348
648912577	100	40.24	8	81	14	95	1.0e-12	65.1	COG0633	Ferredoxin	102
648912578	244	61.54	21	228	1	204	2.0e-87	315	COG1636	Predicted ATPase, Adenine nucleotide alpha hydrolases (AANH) superfamily	204
648912579	473	71.18	6	470	1	464	0.0e+00	772	COG1027	Aspartate ammonia-lyase	471
648912580	404	39.01	8	403	1	393	3.0e-100	358	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
648912582	491	45.07	12	485	1	471	0.0e+00	506	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
648912583	347	46.22	1	340	2	339	1.0e-103	370	COG1064	D-arabinose 1-dehydrogenase, Zn-dependent alcohol dehydrogenase family	339
648912584	152	25.49	1	152	32	182	1.0e-16	79.3	COG2020	Protein-S-isoprenylcysteine O-methyltransferase Ste14	187
648912585	247	42.34	9	245	3	237	2.0e-56	212	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
648912592	447	57.84	88	291	1	203	8.0e-85	307	COG0108	3,4-dihydroxy-2-butanone 4-phosphate synthase	203
648912595	314	31.36	1	307	1	351	2.0e-52	199	COG0484	DnaJ-class molecular chaperone with C-terminal Zn finger domain	371
648912596	411	41.19	4	411	16	447	3.0e-79	289	COG2233	Xanthine/uracil permease	451
648912597	219	50.47	7	218	6	219	1.0e-68	252	COG0283	Cytidylate kinase	222
648912598	561	58.61	2	546	1	537	0.0e+00	587	COG0539	Ribosomal protein S1	541
648912599	104	47.92	1	96	2	91	3.0e-26	109	COG0776	Bacterial nucleoid DNA-binding protein	94
648912600	381	48.75	16	374	9	367	7.0e-129	453	COG1485	Predicted ATPase	367
648912601	141	62.22	2	136	1	135	4.0e-56	209	COG0105	Nucleoside diphosphate kinase	135
648912602	364	57.67	2	351	1	349	0.0e+00	465	COG0820	Adenine C2-methylase RlmN of 23S rRNA A2503 and tRNA A37	349
648912603	251	43.09	2	247	3	246	2.0e-57	215	COG3063	Tfp pilus assembly protein PilF	250
648912605	421	45.43	5	409	2	361	1.0e-128	453	COG0821	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase IspG/GcpE	361
648912606	328	59.24	5	316	3	314	4.0e-117	414	COG0462	Phosphoribosylpyrophosphate synthetase	314
648912607	190	46.81	2	95	1	93	4.0e-25	108	COG1825	Ribosomal protein L25 (general stress protein Ctc)	93
648912608	712	18.05	40	300	32	296	6.0e-08	53.2	COG0741	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)	296
648912610	348	48.54	4	344	9	348	8.0e-118	417	COG1613	ABC-type sulfate transport system, periplasmic component	348
648912611	143	43.75	1	143	1	144	9.0e-46	175	COG2867	Ribosome association toxin PasT (RatA) of the RatAB toxin-antitoxin module	146
648912612	94	45.74	1	94	3	96	1.0e-22	97.7	COG2914	Putative antitoxin component PasI (RatB) of the RatAB toxin-antitoxin module, ubiquitin-RnfH superfamily	99
648912613	191	55.85	4	191	2	189	3.0e-74	270	COG0193	Peptidyl-tRNA hydrolase	190
648912616	129	19.66	13	125	29	145	5.0e-06	43.7	COG5652	VanZ like family protein (function unknown)	148
648912618	187	23.41	2	186	10	211	4.0e-06	44.5	COG2755	Lysophospholipase L1 or related esterase	216
648912620	720	44.75	3	716	2	709	0.0e+00	694	COG2217	Cation transport ATPase	713
648912621	315	48.73	1	315	1	316	9.0e-76	277	COG0385	Predicted Na+-dependent transporter	319
648912622	125	54.05	2	111	1	111	2.0e-33	134	COG0360	Ribosomal protein S6	112
648912623	98	32	1	98	3	102	9.0e-20	88.5	COG2965	Primosomal replication protein N	103
648912624	76	68.66	3	69	9	75	6.0e-20	89.1	COG0238	Ribosomal protein S18	75
648912625	151	56.38	1	149	1	148	3.0e-40	157	COG0359	Ribosomal protein L9	148
648912626	358	38.41	45	358	29	340	4.0e-77	281	COG2951	Membrane-bound lytic murein transglycosylase B	343
648912627	718	41.26	20	524	1	503	6.0e-128	451	COG2812	DNA polymerase III, gamma/tau subunits	515
648912628	111	52.83	1	106	1	104	4.0e-23	99	COG0718	Conserved DNA-binding protein YbaB (function unknown)	105
648912629	636	20.65	118	596	26	490	3.0e-36	147	COG0366	Glycosidase	505
648912630	1338	24.12	478	1197	1	660	2.0e-34	142	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
648912634	456	41.5	1	451	4	447	0.0e+00	486	COG0160	4-aminobutyrate aminotransferase or related aminotransferase	447
648912635	510	30.38	33	498	5	452	1.0e-84	307	COG0076	Glutamate or tyrosine decarboxylase or a related PLP-dependent protein	460
648912636	145	22.45	1	144	5	138	8.0e-06	43.1	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
648912638	521	68.83	198	521	2	315	0.0e+00	550	COG0519	GMP synthase, PP-ATPase domain/subunit	315
648912641	148	56.76	1	148	6	152	1.0e-50	192	COG0691	tmRNA-binding protein	153
648912643	67	62.69	1	67	1	67	5.0e-25	105	COG1278	Cold shock protein, CspA family	67
648912644	123	46.23	18	123	2	107	2.0e-30	124	COG2127	ATP-dependent Clp protease adapter protein ClpS	107
648912645	760	46.2	1	748	1	786	0.0e+00	850	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
648912648	572	43.93	1	572	1	577	0.0e+00	598	COG0018	Arginyl-tRNA synthetase	577
648912650	224	62.33	1	214	5	219	4.0e-72	264	COG0274	Deoxyribose-phosphate aldolase	228
648912652	309	35.99	2	305	1	310	2.0e-53	203	COG0524	Sugar or nucleoside kinase, ribokinase family	311
648912653	400	23.57	15	393	14	414	3.0e-34	140	COG0814	Amino acid permease	415
648912654	478	48.6	15	475	9	468	0.0e+00	502	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
648912655	412	51.35	16	409	41	446	0.0e+00	462	COG0160	4-aminobutyrate aminotransferase or related aminotransferase	447
648912656	252	32.24	9	250	1	245	2.0e-40	159	COG1414	DNA-binding transcriptional regulator, IclR family	246
648912658	297	21.99	51	288	49	289	5.0e-06	45.2	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
648912660	538	25.55	131	516	8	374	8.0e-29	121	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
648912661	206	46.83	5	204	3	206	3.0e-63	234	COG0135	Phosphoribosylanthranilate isomerase	208
648912662	300	25	14	138	12	135	1.0e-05	44.4	COG2510	Uncharacterized membrane protein	140
648912663	212	41.71	22	196	1	169	1.0e-49	189	COG3663	G:T/U-mismatch repair DNA glycosylase	169
648912664	400	67.59	5	399	1	393	0.0e+00	677	COG0133	Tryptophan synthase beta chain	396
648912665	173	33.33	30	168	23	168	3.0e-12	65	COG3161	4-hydroxybenzoate synthetase (chorismate-pyruvate lyase)	174
648912667	231	40.6	2	223	12	245	1.0e-54	206	COG0846	NAD-dependent protein deacetylase, SIR2 family	250
648912668	350	52.57	11	339	2	330	1.0e-114	406	COG0502	Biotin synthase or related enzyme	335
648912669	219	64.38	1	219	4	222	2.0e-103	368	COG0692	Uracil DNA glycosylase	223
648912670	336	41.93	1	314	3	314	7.0e-91	327	COG0180	Tryptophanyl-tRNA synthetase	314
648912671	857	55.76	5	857	1	782	0.0e+00	962	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
648912672	590	35.58	8	569	5	566	2.0e-107	383	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
648912675	587	34.24	37	584	21	567	1.0e-100	360	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
648912676	311	33.44	3	309	1	309	2.0e-81	295	COG0167	Dihydroorotate dehydrogenase	310
648912677	121	31.53	1	110	1	111	5.0e-15	73.2	COG0789	DNA-binding transcriptional regulator, MerR family	124
648912678	221	23.71	30	220	3	179	2.0e-21	96.1	COG3545	Predicted esterase of the alpha/beta hydrolase fold	181
648912679	435	18.56	39	424	43	386	5.0e-08	52.5	COG2814	Predicted arabinose efflux permease, MFS family	394
648912686	1028	33.83	3	999	2	1009	0.0e+00	799	COG0841	Multidrug efflux pump subunit AcrB	1009
648912689	241	27.95	14	241	34	258	6.0e-30	124	COG3713	Outer membrane scaffolding protein for murein synthesis, MipA/OmpV family	258
648912690	157	25.23	29	135	12	118	2.0e-11	62.3	COG1846	DNA-binding transcriptional regulator, MarR family	126
648912692	319	39.93	3	268	1	268	4.0e-42	165	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
648912693	137	23.88	3	136	7	139	4.0e-10	57.2	COG1585	Membrane protein implicated in regulation of membrane protease activity	140
648912695	304	22.62	49	267	11	210	1.0e-12	67.6	COG3619	Uncharacterized membrane protein YoaK, UPF0700 family	226
648912696	316	39.01	1	313	69	387	3.0e-92	331	COG1092	23S rRNA G2069 N7-methylase RlmK or C1962 C5-methylase RlmI	393
648912697	443	42.86	1	443	27	472	7.0e-120	424	COG0513	Superfamily II DNA and RNA helicase	513
648912700	197	29	1	179	3	202	8.0e-30	123	COG3017	Outer membrane lipoprotein LolB, involved in outer membrane biogenesis	206
648912701	281	43.36	8	281	4	289	7.0e-85	307	COG1947	4-diphosphocytidyl-2C-methyl-D-erythritol kinase	289
648912706	469	58.54	212	455	1	244	2.0e-84	306	COG0007	Uroporphyrinogen-III methylase (siroheme synthase)	244
648912708	275	54.51	1	275	1	273	5.0e-96	344	COG0266	Formamidopyrimidine-DNA glycosylase	273
648912710	245	68.86	3	164	1	165	3.0e-69	255	COG0678	Peroxiredoxin	165
648912711	468	33.91	2	458	1	454	4.0e-98	351	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
648912713	111	40.82	11	107	19	116	8.0e-13	65.4	COG0599	Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family	124
648912714	118	35.35	22	118	7	105	2.0e-15	74.6	COG0607	Rhodanese-related sulfurtransferase	110
648912715	161	41.73	37	161	11	137	8.0e-28	116	COG3439	Uncharacterized conserved protein, DUF302 family	137
648912716	237	46.88	17	235	1	224	1.0e-65	242	COG0220	tRNA G46 methylase TrmB	227
648912717	361	29.97	103	361	2	284	2.0e-22	100	COG1408	Predicted phosphohydrolase, MPP superfamily	284
648912718	584	41.62	42	582	2	528	0.0e+00	581	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
648912721	308	39.8	1	301	2	271	8.0e-70	257	COG0130	tRNA U55 pseudouridine synthase TruB, may also work on U342 of tmRNA	271
648912723	123	47.79	9	119	5	117	2.0e-29	120	COG0858	Ribosome-binding factor A	118
648912724	348	31.18	3	348	1	340	4.0e-47	182	COG0673	Predicted dehydrogenase	342
648912725	348	62.46	1	282	3	279	6.0e-92	331	COG0468	RecA/RadA recombinase	279
648912726	241	49.32	91	235	7	152	7.0e-45	173	COG0590	tRNA(Arg) A34 adenosine deaminase TadA	152
648912727	313	47.6	3	294	2	290	5.0e-95	341	COG0324	tRNA A37 N6-isopentenylltransferase MiaA	308
648912728	504	49.9	1	500	6	508	0.0e+00	561	COG4262	Predicted spermidine synthase with an N-terminal membrane domain	508
648912729	128	43.55	5	128	9	132	2.0e-23	101	COG3766	Uncharacterized membrane protein YjfL, UPF0719 family	133
648912731	340	34.42	4	338	6	340	3.0e-81	295	COG4260	Membrane protease subunit, stomatin/prohibitin family, contains C-terminal Zn-ribbon domain	345
648912734	118	41.03	1	116	10	125	9.0e-26	108	COG1586	S-adenosylmethionine decarboxylase or arginine decarboxylase	136
648912735	538	17.96	63	534	2	444	6.0e-07	49.5	COG1232	Protoporphyrinogen oxidase	444
648912738	148	25.9	1	138	4	141	3.0e-11	61.5	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
648912739	352	54.12	11	350	1	338	3.0e-114	405	COG0547	Anthranilate phosphoribosyltransferase	338
648912740	188	48.17	25	186	1	156	7.0e-52	196	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
648912741	187	41.27	1	187	3	191	1.0e-45	176	COG2353	Polyisoprenoid-binding periplasmic protein YceI	192
648912743	512	32.15	61	506	60	438	3.0e-63	236	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
648912745	301	65.52	10	297	14	303	4.0e-130	457	COG0408	Coproporphyrinogen III oxidase	303
648912746	619	52.91	1	617	8	575	0.0e+00	799	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
648912750	145	52.99	6	121	2	118	4.0e-39	153	COG3536	Uncharacterized conserved protein, DUF971 family	120
648912751	307	45.78	1	307	2	291	4.0e-79	288	COG1234	Ribonuclease BN, tRNA processing enzyme	292
648912752	245	56.9	10	245	1	238	3.0e-80	291	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
648912753	635	43.7	1	533	1	530	0.0e+00	539	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
648912754	69	47.76	1	67	1	67	1.0e-13	68.5	COG2608	Copper chaperone CopZ	71
648912755	397	38.74	2	381	3	384	7.0e-65	241	COG2814	Predicted arabinose efflux permease, MFS family	394
648912757	435	51.06	1	319	1	329	7.0e-103	367	COG0460	Homoserine dehydrogenase	333
648912758	123	35.77	1	123	5	127	4.0e-26	110	COG3737	Uncharacterized conserved protein, contains Mth938-like domain	127
648912759	272	37.02	9	262	2	254	3.0e-54	205	COG0171	NH3-dependent NAD+ synthetase	268
648912761	161	49.34	1	151	3	154	4.0e-51	193	COG1607	Acyl-CoA hydrolase	157
648912762	356	39.46	64	356	33	322	1.0e-62	234	COG0598	Mg2+ and Co2+ transporter CorA	322
648912763	603	69.55	1	601	2	602	0.0e+00	1028	COG1217	Predicted membrane GTPase involved in stress response	603
648912765	154	54.19	1	154	1	154	3.0e-48	183	COG2193	Bacterioferritin (cytochrome b1)	157
648912766	157	63.69	1	157	1	157	2.0e-50	191	COG2193	Bacterioferritin (cytochrome b1)	157
648912767	170	48.06	36	164	10	134	2.0e-44	171	COG1607	Acyl-CoA hydrolase	157
648912768	312	25	15	309	6	282	6.0e-17	81.7	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
648912769	190	41.9	2	179	5	169	2.0e-43	168	COG0521	Molybdopterin biosynthesis enzyme MoaB	169
648912770	240	41.07	1	220	18	233	2.0e-50	192	COG0005	Purine nucleoside phosphorylase	262
648912772	356	35.69	18	342	22	339	2.0e-42	167	COG0628	Predicted PurR-regulated permease PerM	355
648912773	344	60.58	2	344	1	345	0.0e+00	493	COG0150	Phosphoribosylaminoimidazole (AIR) synthetase	345
648912775	214	32.03	88	206	14	140	1.0e-13	70.2	COG0663	Carbonic anhydrase or acetyltransferase, isoleucine patch superfamily	176
648912776	610	29.33	10	600	16	557	8.0e-94	338	COG1626	Neutral trehalase	558
648912777	411	17.18	8	407	16	418	3.0e-18	86.4	COG0738	Fucose permease	422
648912779	431	43.3	17	429	17	425	2.0e-117	416	COG0128	5-enolpyruvylshikimate-3-phosphate synthase	428
648912780	177	44.83	2	175	1	171	4.0e-47	180	COG0221	Inorganic pyrophosphatase	171
648912781	194	64.17	1	186	3	189	2.0e-83	302	COG0512	Anthranilate/para-aminobenzoate synthase component II	191
648912783	256	31.75	8	251	12	258	6.0e-39	154	COG3568	Metal-dependent hydrolase, endonuclease/exonuclease/phosphatase family	259
648912784	294	41.84	38	294	2	283	1.0e-71	263	COG1469	GTP cyclohydrolase FolE2	289
648912785	385	47.46	1	385	6	396	0.0e+00	470	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
648912786	259	27.14	5	259	1	266	4.0e-39	155	COG1018	Ferredoxin-NADP reductase	266
648912787	459	62.61	1	456	1	455	0.0e+00	670	COG1066	Predicted ATP-dependent serine protease	456
648912788	492	41.65	8	415	1	405	9.0e-96	344	COG0793	C-terminal processing protease CtpA/Prc, contains a PDZ domain	406
648912789	588	29.84	222	587	40	418	5.0e-51	196	COG4942	Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB	420
648912790	184	51.88	1	160	3	161	3.0e-47	181	COG3045	Periplasmic catabolite regulation protein CreA (function unknown)	165
648912791	182	52.72	1	182	11	194	1.0e-61	229	COG1678	Putative transcriptional regulator, AlgH/UPF0301 family	194
648912792	153	44.03	7	139	2	135	8.0e-36	143	COG0816	RNase H-fold protein, predicted Holliday junction resolvase in Firmicutes and mycoplasms, involved in anti-termination at Rho-dependent terminators	141
648912793	212	38.61	12	212	1	202	2.0e-35	142	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
648912794	476	58.58	1	476	4	481	0.0e+00	696	COG0064	Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit	483
648912795	291	39.66	6	289	11	299	9.0e-75	273	COG2990	Uncharacterized protein VirK/YbjX	300
648912796	485	51.02	1	481	4	474	0.0e+00	521	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
648912797	96	38.54	1	96	1	96	4.0e-19	86.4	COG0721	Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit	96
648912798	345	57.06	7	343	3	341	1.0e-110	393	COG1077	Actin-like ATPase involved in cell morphogenesis	342
648912799	287	30.4	18	287	8	280	1.0e-38	153	COG1792	Cell shape-determining protein MreC	284
648912800	167	33.56	15	159	11	156	4.0e-09	54.4	COG2891	Cell shape-determining protein MreD	167
648912801	645	34.46	2	602	26	599	8.0e-122	431	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
648912802	372	42.9	9	369	4	375	5.0e-76	278	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
648912803	221	36.99	1	219	1	203	1.0e-33	136	COG2095	Small neutral amino acid transporter SnatA, MarC family	203
648912804	447	40.13	1	447	15	468	2.0e-109	389	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
648912805	279	33.57	2	279	21	296	2.0e-42	166	COG0501	Zn-dependent protease with chaperone function	302
648912806	1211	29.85	1	1187	1	1139	0.0e+00	602	COG1074	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)	1139
648912807	302	38.51	1	302	22	343	4.0e-79	288	COG2837	Periplasmic deferrochelatase/peroxidase EfeB	352
648912809	116	37.29	1	116	2	117	2.0e-28	117	COG1393	Arsenate reductase and related proteins, glutaredoxin family	117
648912811	206	46.7	8	204	2	198	2.0e-69	255	COG0353	Recombinational DNA repair protein RecR	198
648912813	416	46.63	3	416	4	408	3.0e-107	382	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
648912814	241	47.53	17	238	1	223	4.0e-74	271	COG1136	ABC-type lipoprotein export system, ATPase component	226
648912817	133	51.58	4	98	3	97	2.0e-23	101	COG1188	Ribosomal 50S subunit-recycling heat shock protein, contains S4 domain	100
648912818	319	66.56	2	318	1	317	0.0e+00	507	COG0825	Acetyl-CoA carboxylase alpha subunit	317
648912819	430	32.54	7	249	19	267	6.0e-41	161	COG0037	tRNA(Ile)-lysidine synthase TilS/MesJ	298
648912820	199	35.29	7	193	2	181	3.0e-32	131	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
648912821	201	26.88	13	164	8	164	7.0e-06	43.9	COG3073	Negative regulator of sigma E activity	213
648912822	262	32.45	4	260	1	259	4.0e-49	188	COG0566	tRNA G18 (ribose-2'-O)-methylase SpoU	260
648912823	220	36.41	10	218	6	216	9.0e-39	153	COG3318	Uncharacterized conserved protein YecA, UPF0149 family, contains C-terminal Zn-binding SEC-C motif	216
648912824	163	44.16	1	151	1	152	5.0e-16	77.2	COG2839	Uncharacterized conserved protein YqgC, DUF456 family	160
648912825	319	36.33	13	265	1	249	2.0e-51	196	COG0037	tRNA(Ile)-lysidine synthase TilS/MesJ	298
648912826	284	49.13	1	282	5	278	1.0e-70	259	COG0682	Prolipoprotein diacylglyceryltransferase	287
648912827	376	41.53	5	371	1	367	8.0e-80	290	COG2866	Murein tripeptide amidase MpaA	374
648912828	156	21.77	1	141	5	146	2.0e-10	58.4	COG2110	O-acetyl-ADP-ribose deacetylase (regulator of RNase III), contains Macro domain	179
648912829	295	53.96	30	292	4	264	4.0e-81	295	COG0548	Acetylglutamate kinase	265
648912831	665	43.05	1	664	1	638	0.0e+00	651	COG0323	DNA mismatch repair ATPase MutL	638
648912832	279	35.48	1	279	5	314	4.0e-57	215	COG0627	S-formylglutathione hydrolase FrmB	316
648912833	569	45.96	1	566	1	500	0.0e+00	572	COG0442	Prolyl-tRNA synthetase	500
648912834	450	44.36	64	449	14	389	3.0e-93	335	COG1686	D-alanyl-D-alanine carboxypeptidase	389
648912835	508	53.76	5	346	3	347	9.0e-121	427	COG1171	Threonine dehydratase	347
648912837	379	52.85	4	372	8	367	0.0e+00	462	COG2021	Homoserine acetyltransferase	368
648912840	334	44.41	1	332	2	340	2.0e-94	338	COG1816	Adenosine deaminase	345
648912841	67	51.52	1	66	1	64	1.0e-15	74.6	COG1942	Phenylpyruvate tautomerase PptA, 4-oxalocrotonate tautomerase family	69
648912842	199	24.14	1	195	1	202	1.0e-21	96.1	COG2854	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic MlaC component	202
648912843	416	34.5	1	393	23	411	1.0e-80	294	COG0617	tRNA nucleotidyltransferase/poly(A) polymerase	412
648912844	436	25.11	1	432	1	438	9.0e-35	141	COG4487	Uncharacterized protein	438
648912845	486	42.2	3	485	93	591	0.0e+00	512	COG4178	ABC-type uncharacterized transport system, permease and ATPase components	604
648912846	708	21.18	15	708	41	768	2.0e-28	121	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
648912847	343	71.04	16	343	4	331	0.0e+00	533	COG2255	Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit	332
648912851	129	71.32	1	129	1	127	3.0e-53	200	COG3445	Autonomous glycyl radical cofactor GrcA	127
648912852	384	42.04	8	384	1	370	1.0e-108	386	COG4394	Uncharacterized protein	370
648912853	186	45.74	1	128	3	129	5.0e-32	130	COG0231	Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)	131
648912854	225	59.56	1	225	1	220	1.0e-84	306	COG0036	Pentose-5-phosphate-3-epimerase	220
648912855	147	20.18	31	140	25	138	6.0e-10	56.9	COG3678	Periplasmic protein refolding chaperone Spy/CpxP family	160
648912856	288	58.54	1	285	4	285	2.0e-104	371	COG2607	Predicted ATPase, AAA+ superfamily	287
648912857	235	42.23	23	227	1	198	1.0e-62	233	COG0307	Riboflavin synthase alpha chain	204
648912858	89	59.55	1	89	2	90	1.0e-25	107	COG0776	Bacterial nucleoid DNA-binding protein	94
648912859	817	65.41	6	797	2	782	0.0e+00	1178	COG0466	ATP-dependent Lon protease, bacterial type	782
648912860	89	47.19	1	89	2	90	5.0e-26	109	COG2921	Putative lipoic acid-binding regulatory protein	90
648912861	214	55.45	1	200	11	211	6.0e-75	273	COG0321	Lipoate-protein ligase B	221
648912862	332	64.82	19	323	1	306	0.0e+00	498	COG0320	Lipoate synthase	306
648912863	404	45.28	1	404	2	412	7.0e-112	397	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
648912864	175	32.05	16	169	1	145	3.0e-35	141	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
648912865	271	31.6	4	271	19	286	3.0e-48	185	COG1562	Phytoene/squalene synthetase	288
648912866	603	39.6	1	601	1	567	0.0e+00	522	COG4232	Thiol:disulfide interchange protein	569
648912867	293	46.38	3	277	6	267	6.0e-59	221	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
648912868	323	43.04	6	321	1	285	7.0e-70	257	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
648912869	374	49.45	8	368	1	346	9.0e-122	430	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
648912870	225	50.45	1	224	1	224	2.0e-69	255	COG2003	DNA repair protein RadC, contains a helix-hairpin-helix DNA-binding motif	224
648912871	453	36.17	31	445	2	411	4.0e-82	298	COG0617	tRNA nucleotidyltransferase/poly(A) polymerase	412
648912873	222	39.81	12	222	12	218	2.0e-45	175	COG4122	Predicted O-methyltransferase YrrM	219
648912874	225	22.88	8	225	26	261	1.0e-24	106	COG1729	Periplasmic TolA-binding protein (function unknown)	262
648912875	161	68.94	1	161	2	160	7.0e-60	223	COG0041	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase	162
648912876	352	45.3	4	348	1	351	3.0e-95	342	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
648912877	243	36.48	5	243	5	242	6.0e-48	184	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
648912878	220	45.03	1	189	1	188	6.0e-48	184	COG3658	Cytochrome b	192
648912879	295	40.07	25	289	20	282	1.0e-53	203	COG0063	NAD(P)H-hydrate repair enzyme Nnr, NAD(P)H-hydrate dehydratase domain	284
648912880	120	43.09	1	117	1	123	1.0e-13	68.7	COG0239	Fluoride ion exporter CrcB/FEX, affects chromosome condensation	126
648912881	159	55.9	1	159	63	222	2.0e-32	131	COG3235	Uncharacterized membrane protein	223
648912882	1017	35.88	343	1013	199	856	0.0e+00	486	COG1674	DNA segregation ATPase FtsK/SpoIIIE and related proteins	858
648912883	136	29.93	2	128	1	136	2.0e-14	71.6	COG3187	Heat shock protein HslJ	142
648912884	235	41.23	1	224	4	227	2.0e-42	165	COG2378	Predicted DNA-binding transcriptional regulator YafY, contains an HTH and WYL domains	311
648912885	217	28.84	6	212	4	211	4.0e-23	101	COG0625	Glutathione S-transferase	211
648912886	353	56.78	1	351	2	352	1.0e-128	453	COG0407	Uroporphyrinogen-III decarboxylase	352
648912887	406	30.94	1	400	1	397	8.0e-77	281	COG3071	Uncharacterized conserved protein HemY, contains two TPR repeats	400
648912888	475	35.37	8	379	17	389	5.0e-72	265	COG2959	Uncharacterized conserved protein HemX (no evidence of involvement in heme biosynthesis)	391
648912890	286	45.24	35	285	16	266	2.0e-67	249	COG1526	Formate dehydrogenase assembly factor FdhD	266
648912891	315	28.71	3	305	2	303	3.0e-46	179	COG3058	Formate dehydrogenase maturation protein FdhE	308
648912892	258	35.45	1	255	2	266	6.0e-55	207	COG1018	Ferredoxin-NADP reductase	266
648912893	587	39.09	10	582	1	567	0.0e+00	473	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
648912895	470	34.39	1	466	1	410	2.0e-100	359	COG0498	Threonine synthase	411
648912896	435	57.97	3	431	4	433	0.0e+00	601	COG2256	Replication-associated recombination protein RarA (DNA-dependent ATPase)	436
648912897	748	35.3	23	748	31	719	0.0e+00	477	COG4773	Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid	719
648912899	501	18.94	3	372	1	391	2.0e-26	114	COG3182	Uncharacterized iron-regulated membrane protein	442
648912901	698	17.7	30	698	61	768	6.0e-34	139	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
648912902	595	47.55	9	595	3	587	0.0e+00	573	COG0369	Sulfite reductase, alpha subunit (flavoprotein)	587
648912905	320	50.8	4	313	3	302	1.0e-93	336	COG0492	Thioredoxin reductase	305
648912906	613	48.36	7	612	3	581	0.0e+00	661	COG0322	Excinuclease UvrABC, nuclease subunit	581
648912907	190	62.43	7	179	2	169	5.0e-54	203	COG3198	Uncharacterized protein	172
648912908	483	35.83	33	458	1	386	6.0e-82	298	COG0348	Polyferredoxin	386
648912909	659	63.35	1	659	6	662	0.0e+00	1051	COG0021	Transketolase	663
648912910	669	14.87	53	643	41	615	2.0e-31	131	COG1368	Phosphoglycerol transferase MdoB or a related enzyme of AlkP superfamily	650
648912911	334	27.65	1	332	1	311	5.0e-39	155	COG0451	Nucleoside-diphosphate-sugar epimerase	314
648912913	246	50.21	14	246	11	239	1.0e-67	249	COG0284	Orotidine-5'-phosphate decarboxylase	240
648912914	215	44.5	1	214	1	178	2.0e-48	185	COG0563	Adenylate kinase or related kinase	178
648912916	253	59.29	1	253	1	245	7.0e-95	340	COG1212	CMP-2-keto-3-deoxyoctulosonic acid synthetase	247
648912917	66	56.67	7	66	1	60	4.0e-18	83	COG2835	Uncharacterized conserved protein YbaR, Trm112 family	60
648912918	193	34.62	2	183	4	178	1.0e-28	119	COG3184	Uncharacterized protein	183
648912919	343	47.79	9	339	1	328	1.0e-89	323	COG1663	Tetraacyldisaccharide-1-P 4'-kinase	336
648912921	451	50.34	10	442	6	437	0.0e+00	489	COG1570	Exonuclease VII, large subunit	440
648912922	165	35.88	1	163	14	171	3.0e-35	141	COG1881	Uncharacterized conserved protein, phosphatidylethanolamine-binding protein (PEBP) family	174
648912923	920	53.54	11	896	3	803	0.0e+00	999	COG0188	DNA gyrase/topoisomerase IV, subunit A	804
648912924	458	42.92	1	458	7	458	0.0e+00	476	COG0773	UDP-N-acetylmuramate-alanine ligase	459
648912926	356	53.61	1	356	2	345	6.0e-128	450	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
648912929	154	32.89	1	146	1	149	2.0e-28	118	COG2731	Beta-galactosidase, beta subunit	154
648912931	213	55.92	1	211	1	190	1.0e-78	285	COG0066	3-isopropylmalate dehydratase small subunit	191
648912933	468	56.26	2	468	1	423	0.0e+00	635	COG0065	Homoaconitase/3-isopropylmalate dehydratase large subunit	423
648912936	233	37.22	1	222	1	218	4.0e-59	221	COG1556	L-lactate utilization protein LutC, contains LUD domain	218
648912937	481	49.57	9	474	1	459	0.0e+00	616	COG1139	L-lactate utilization protein LutB, contains a ferredoxin-type domain	459
648912938	72	62.5	1	72	1	72	5.0e-18	82.6	COG2841	Uncharacterized conserved protein YdcH, DUF465 family	72
648912939	249	33.01	1	187	2	207	2.0e-25	109	COG0778	Nitroreductase	207
648912941	416	68.29	7	415	6	413	0.0e+00	660	COG0112	Glycine/serine hydroxymethyltransferase	413
648912942	515	40.13	201	507	1	300	2.0e-83	303	COG1732	Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)	300
648912943	222	30.37	10	218	9	212	1.0e-24	107	COG4912	3-methyladenine DNA glycosylase AlkD	222
648912944	182	34.04	29	169	7	145	6.0e-22	97.4	COG4815	Uncharacterized protein	145
648912945	313	31.37	1	313	2	323	6.0e-35	141	COG1275	Tellurite resistance protein TehA and related permeases	329
648912947	149	35.71	29	140	15	126	3.0e-13	67.6	COG1846	DNA-binding transcriptional regulator, MarR family	126
648912950	237	32.5	42	236	58	257	1.0e-31	130	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
648912951	284	58.65	9	245	1	237	4.0e-99	354	COG1125	ABC-type proline/glycine betaine transport system, ATPase component	309
648912952	439	20.23	14	436	25	446	2.0e-13	71	COG2271	Sugar phosphate permease	448
648912953	216	33.53	46	211	33	190	7.0e-27	114	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
648912962	675	65.87	8	674	2	663	0.0e+00	1079	COG0556	Excinuclease UvrABC helicase subunit UvrB	663
648912965	468	52.49	18	459	1	435	0.0e+00	556	COG0305	Replicative DNA helicase	435
648912966	222	31.94	3	217	5	181	1.0e-24	106	COG4970	Tfp pilus assembly protein FimT	181
648912967	222	24.69	20	180	8	154	4.0e-15	75	COG4967	Tfp pilus assembly protein PilV	162
648912968	293	25.88	16	293	11	318	7.0e-23	101	COG4966	Tfp pilus assembly protein PilW	318
648912969	186	38.71	14	185	12	192	2.0e-32	132	COG4726	Tfp pilus assembly protein PilX	196
648912970	157	33.98	9	109	7	107	7.0e-14	70	COG4968	Tfp pilus assembly protein PilE	139
648912971	478	25.9	176	465	2	281	3.0e-18	87	COG0790	TPR repeat	292
648912972	815	45.75	26	721	2	705	0.0e+00	714	COG0557	Exoribonuclease R	706
648912977	338	39.44	15	334	9	320	9.0e-77	280	COG0042	tRNA-dihydrouridine synthase	323
648912978	317	47.13	4	317	2	311	3.0e-98	351	COG1957	Inosine-uridine nucleoside N-ribohydrolase	311
648912980	441	35.01	1	433	1	429	5.0e-99	355	COG1253	Hemolysin or related protein, contains CBS domains	429
648912981	497	33.19	48	497	1	438	4.0e-72	265	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
648912983	393	57.65	2	392	14	400	0.0e+00	552	COG4992	Acetylornithine/succinyldiaminopimelate/putrescine aminotransferase	404
648912984	688	45.31	19	656	1	649	0.0e+00	599	COG0210	Superfamily I DNA or RNA helicase	655
648912985	517	26.38	1	506	1	470	4.0e-68	252	COG5339	Uncharacterized conserved protein YdgA, DUF945 family	479
648912987	280	58.42	1	279	3	279	3.0e-123	435	COG2877	3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase	279
648912988	127	73.02	2	127	1	126	6.0e-52	195	COG0853	Aspartate 1-decarboxylase	126
648912989	108	40.2	6	106	3	104	4.0e-24	103	COG1324	Uncharacterized protein involved in tolerance to divalent cations	104
648912991	222	33.94	1	218	4	202	7.0e-45	173	COG0560	Phosphoserine phosphatase	212
648912994	855	39.95	29	855	36	863	0.0e+00	812	COG2844	UTP:GlnB (protein PII) uridylyltransferase	867
648912995	409	24.54	18	392	6	346	2.0e-22	100	COG1566	Multidrug resistance efflux pump	352
648912996	735	33.67	9	699	19	696	0.0e+00	502	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
648912997	429	18.14	43	417	45	441	6.0e-20	92.1	COG1538	Outer membrane protein TolC	457
648912998	261	47.69	1	258	1	260	4.0e-75	274	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
648912999	271	44.4	12	270	2	239	4.0e-70	258	COG0565	tRNA C32,U32 (ribose-2'-O)-methylase TrmJ or a related methyltransferase	242
648913000	282	67.82	2	282	1	289	8.0e-90	323	COG3782	Uncharacterized protein	289
648913001	418	39.4	120	418	53	354	4.0e-77	282	COG0144	16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family	355
648913002	103	61.17	1	103	1	103	2.0e-44	170	COG0278	Glutaredoxin-related protein	105
648913003	208	57.89	1	208	2	210	2.0e-79	288	COG0035	Uracil phosphoribosyltransferase	210
648913004	107	63.81	1	105	1	105	1.0e-34	137	COG4390	Uncharacterized protein	106
648913005	268	46.82	1	264	1	264	6.0e-78	284	COG5266	Uncharacterized conserved protein, contains GH25 family domain	264
648913008	741	77.6	1	741	2	742	0.0e+00	1274	COG2838	Monomeric isocitrate dehydrogenase	744
648913009	147	34.69	1	145	1	147	6.0e-24	103	COG0698	Ribose 5-phosphate isomerase RpiB	151
648913010	459	32.1	13	445	12	440	3.0e-66	246	COG0534	Na+-driven multidrug efflux pump	455
648913011	257	29.56	2	251	6	259	2.0e-32	132	COG3680	Uncharacterized protein	259
648913012	346	34.5	4	343	3	289	1.0e-77	283	COG0812	UDP-N-acetylenolpyruvoylglucosamine reductase	291
648913013	218	19.8	1	194	5	201	5.0e-11	61.6	COG1309	DNA-binding transcriptional regulator, AcrR family	201
648913014	258	24.12	12	237	8	263	8.0e-18	84.2	COG0451	Nucleoside-diphosphate-sugar epimerase	314
648913015	189	30.26	1	187	8	202	3.0e-31	128	COG3165	Ubiquinone biosynthesis protein UbiJ, contains SCP2 domain	204
648913016	296	46.05	6	293	1	281	1.0e-71	262	COG0061	NAD kinase	281
648913017	520	28.6	1	507	1	501	3.0e-83	302	COG1292	Choline-glycine betaine transporter	537
648913019	216	35.85	1	209	1	203	1.0e-41	162	COG0062	NAD(P)H-hydrate repair enzyme Nnr, NAD(P)H-hydrate epimerase domain	203
648913020	88	26.58	4	82	1	70	6.0e-06	42.5	COG1918	Fe2+ transport system protein FeoA	75
648913021	620	41.89	1	620	1	652	0.0e+00	536	COG0370	Fe2+ transport system protein B	653
648913022	377	64.63	1	376	1	376	0.0e+00	486	COG1929	Glycerate kinase	378
648913023	553	44.36	1	552	1	556	0.0e+00	536	COG0497	DNA repair ATPase RecN	557
648913025	318	38.18	1	318	1	317	8.0e-65	240	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
648913026	182	19.6	6	162	1	199	2.0e-10	59.5	COG1335	Nicotinamidase-related amidase	205
648913027	680	53.26	4	671	10	675	0.0e+00	849	COG1200	RecG-like helicase	677
648913028	144	53.96	1	139	5	142	6.0e-47	179	COG1952	Preprotein translocase subunit SecB	157
648913029	85	48.1	3	80	2	80	1.0e-19	88.1	COG0695	Glutaredoxin	80
648913030	497	43.51	15	497	1	483	0.0e+00	485	COG1530	Ribonuclease G or E	487
648913031	130	47.54	9	130	1	122	3.0e-29	120	COG0818	Diacylglycerol kinase	123
648913032	159	50	1	148	3	151	3.0e-36	144	COG2847	Copper(I)-binding protein	151
648913033	367	57.3	5	356	1	352	0.0e+00	466	COG0482	tRNA U34 2-thiouridine synthase MnmA/TrmU, contains the PP-loop ATPase domain	356
648913034	557	35.14	13	557	1	528	0.0e+00	474	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
648913035	544	65.01	2	543	1	531	0.0e+00	897	COG0504	CTP synthase (UTP-ammonia lyase)	533
648913036	249	40.89	3	245	1	246	1.0e-63	236	COG3338	Carbonic anhydrase	250
648913037	574	42.65	5	568	5	509	0.0e+00	525	COG0155	Sulfite reductase, beta subunit (hemoprotein)	510
648913038	208	49.46	1	185	1	184	2.0e-44	172	COG1386	Chromosome segregation and condensation protein ScpB	184
648913040	314	39.1	1	301	12	322	4.0e-66	245	COG1161	Ribosome biogenesis GTPase A	322
648913041	284	50	1	280	1	285	6.0e-100	357	COG1660	RNase adaptor protein for sRNA GlmZ degradation, contains a P-loop ATPase domain	286
648913042	320	44.27	2	314	1	308	3.0e-86	312	COG1493	Serine kinase of the HPr protein, regulates carbohydrate metabolism	308
648913043	149	38.78	3	147	1	147	4.0e-30	124	COG1762	Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type)	152
648913044	301	41.64	18	297	9	289	8.0e-50	190	COG0382	4-hydroxybenzoate polyprenyltransferase	289
648913047	199	56.7	3	195	1	193	2.0e-69	255	COG0807	GTP cyclohydrolase II	193
648913051	158	42	4	151	3	138	9.0e-35	139	COG0394	Protein-tyrosine-phosphatase	139
648913053	359	52.92	36	357	1	322	1.0e-117	416	COG0158	Fructose-1,6-bisphosphatase	326
648913054	255	61.94	1	247	2	240	1.0e-107	382	COG1126	ABC-type polar amino acid transport system, ATPase component	240
648913055	238	45.58	11	235	1	221	5.0e-56	211	COG0765	ABC-type amino acid transport system, permease component	222
648913056	274	36.02	25	274	11	270	9.0e-35	140	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
648913057	193	18.78	1	180	2	176	7.0e-06	44.1	COG1704	Uncharacterized conserved protein	185
648913058	278	57.04	1	277	1	284	2.0e-105	375	COG0414	Panthothenate synthetase	285
648913059	263	62.12	1	262	1	264	6.0e-100	357	COG0413	Ketopantoate hydroxymethyltransferase	268
648913062	263	24.2	1	261	1	280	1.0e-40	160	COG0421	Spermidine synthase	282
648913063	212	42.51	1	207	1	204	4.0e-56	211	COG2945	Alpha/beta superfamily hydrolase	210
648913065	254	46.81	19	253	1	229	2.0e-58	219	COG0710	3-dehydroquinate dehydratase	231
648913066	230	41.67	7	230	2	229	5.0e-31	127	COG1814	Predicted Fe2+/Mn2+ transporter, VIT1/CCC1 family	229
648913070	164	61.39	1	157	1	158	6.0e-61	226	COG2077	Peroxiredoxin	158
648913071	898	25.07	30	379	19	369	4.0e-34	140	COG0612	Predicted Zn-dependent peptidase	438
648913072	399	42.54	1	399	6	403	7.0e-94	337	COG0303	Molybdopterin biosynthesis enzyme	404
648913073	198	32.99	4	198	1	189	1.0e-35	143	COG0746	Molybdopterin-guanine dinucleotide biosynthesis protein A	192
648913074	155	38	1	150	2	149	5.0e-36	143	COG0314	Molybdopterin synthase catalytic subunit	149
648913075	82	35.71	1	82	1	84	4.0e-12	63	COG1977	Molybdopterin converting factor, small subunit	84
648913076	641	31.33	9	638	1	571	3.0e-129	455	COG3850	Signal transduction histidine kinase, nitrate/nitrite-specific	574
648913077	218	40.38	3	215	1	211	4.0e-53	200	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
648913078	179	25.49	40	179	9	159	6.0e-08	50.8	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
648913079	117	37.82	1	117	2	120	6.0e-25	106	COG1539	Dihydroneopterin aldolase	121
648913080	202	48.51	1	197	3	200	1.0e-46	179	COG0344	Phospholipid biosynthesis protein PlsY, probable glycerol-3-phosphate acyltransferase	200
648913082	279	52.9	1	279	1	292	2.0e-97	349	COG2321	Predicted metalloprotease	295
648913083	460	31.24	3	452	4	459	4.0e-98	351	COG1109	Phosphomannomutase	464
648913084	281	49.47	2	280	1	277	4.0e-97	347	COG2961	23S rRNA A2030 N6-methylase RlmJ	279
648913086	187	42.02	1	187	10	189	7.0e-23	100	COG0558	Phosphatidylglycerophosphate synthase	192
648913094	356	23.68	74	316	28	289	1.0e-12	67.9	COG4974	Site-specific recombinase XerD	300
648913107	100	33.33	13	84	5	72	1.0e-06	45.3	COG3905	Predicted transcriptional regulator	83
648913108	98	33.33	1	89	1	89	3.0e-10	57	COG3668	Plasmid stabilization system protein ParE	98
648913125	354	24.65	5	345	7	342	1.0e-21	97.5	COG3515	Predicted component of the type VI protein secretion system	346
648913126	174	55.49	8	170	2	165	5.0e-52	197	COG3516	Predicted component of the type VI protein secretion system	169
648913127	499	62.37	1	497	1	494	0.0e+00	788	COG3517	Predicted component of the type VI protein secretion system	495
648913128	160	22.5	1	148	1	153	2.0e-19	88.8	COG3157	Type VI protein secretion system component Hcp (secreted cytotoxin)	162
648913129	265	26.14	1	263	17	265	3.0e-29	122	COG4455	Protein of avirulence locus involved in temperature-dependent protein secretion	273
648913130	172	31.1	6	168	4	157	1.0e-19	89.2	COG3518	Predicted component of the type VI protein secretion system	157
648913131	657	30.35	1	657	1	621	4.0e-122	432	COG3519	Type VI protein secretion system component VasA	621
648913132	359	34.6	46	356	18	329	8.0e-70	257	COG3520	Predicted component of the type VI protein secretion system	335
648913133	876	39.45	12	876	1	784	0.0e+00	779	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
648913134	378	25.47	3	369	2	359	1.0e-45	177	COG5351	Uncharacterized protein	367
648913135	758	33.94	2	544	10	550	3.0e-124	439	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
648913136	1182	27	4	1181	5	1183	0.0e+00	603	COG3523	Type VI protein secretion system component VasK	1188
648913137	417	33.04	16	236	39	259	1.0e-41	164	COG3455	Type VI protein secretion system component VasF	262
648913138	448	39.51	1	446	1	446	8.0e-107	381	COG3522	Predicted component of the type VI protein secretion system	446
648913139	217	28.17	10	147	8	142	2.0e-23	102	COG3521	Predicted component of the type VI protein secretion system	159
648913155	346	35.41	1	344	1	349	6.0e-79	288	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
648913156	349	46.22	1	343	5	339	1.0e-104	373	COG1194	Adenine-specific DNA glycosylase, acts on AG and A-oxoG pairs	342
648913157	289	48.61	5	289	4	290	3.0e-77	282	COG1561	Uncharacterized conserved protein YicC, UPF0701 family	290
648913158	246	57.45	7	240	11	230	5.0e-74	270	COG0689	Ribonuclease PH	230
648913159	406	43.93	1	405	1	447	1.0e-116	413	COG0527	Aspartokinase	447
648913160	421	58.25	10	421	1	411	0.0e+00	554	COG0334	Glutamate dehydrogenase/leucine dehydrogenase	411
648913161	236	42.79	7	228	3	218	2.0e-42	165	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
648913162	156	40.67	5	149	20	169	1.0e-20	92.7	COG2137	SOS response regulatory protein OraA/RecX, interacts with RecA	174
648913164	356	33.79	1	356	1	364	4.0e-54	205	COG0795	Lipopolysaccharide export LptBFGC system, permease protein LptF	364
648913165	371	30.68	1	353	2	364	2.0e-50	193	COG0795	Lipopolysaccharide export LptBFGC system, permease protein LptF	364
648913166	469	44.78	16	467	25	482	0.0e+00	479	COG0260	Leucyl aminopeptidase	485
648913168	145	34.93	1	144	1	144	3.0e-27	114	COG2927	DNA polymerase III, chi subunit	144
648913169	271	42.92	39	250	1	204	6.0e-49	187	COG0545	FKBP-type peptidyl-prolyl cis-trans isomerase	205
648913170	208	58.88	2	195	1	197	4.0e-77	280	COG0299	Folate-dependent phosphoribosylglycinamide formyltransferase PurN	200
648913172	285	43.22	1	272	5	276	2.0e-63	236	COG1737	DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains	281
648913173	318	54.81	1	311	9	320	2.0e-119	422	COG0837	Glucokinase	320
648913174	231	31.06	3	231	2	230	2.0e-47	182	COG0363	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase	238
648913175	481	52.25	1	480	2	483	0.0e+00	643	COG0364	Glucose-6-phosphate 1-dehydrogenase	483
648913176	625	40.89	27	624	5	575	0.0e+00	637	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
648913177	212	58.96	1	211	1	211	5.0e-66	243	COG0800	2-keto-3-deoxy-6-phosphogluconate aldolase	211
648913178	224	57.01	2	212	3	215	8.0e-58	216	COG2864	Cytochrome b subunit of formate dehydrogenase	218
648913179	306	41.86	23	237	5	202	1.0e-57	216	COG0437	Fe-S-cluster-containing dehydrogenase component	203
648913180	1017	27.99	2	733	1	595	5.0e-92	332	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
648913183	331	59.7	1	330	2	310	2.0e-130	459	COG0078	Ornithine carbamoyltransferase	310
648913184	289	44.91	119	282	2	168	8.0e-44	171	COG0350	O6-methylguanine-DNA--protein-cysteine methyltransferase	168
648913185	185	45.05	4	185	3	173	3.0e-43	167	COG1881	Uncharacterized conserved protein, phosphatidylethanolamine-binding protein (PEBP) family	174
648913186	264	27.93	143	252	17	127	4.0e-15	75.3	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
648913187	381	34.75	1	378	10	409	7.0e-82	297	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
648913190	194	72.19	47	194	1	151	1.0e-49	189	COG3241	Azurin	151
648913192	917	56.22	2	910	1	822	0.0e+00	1079	COG0653	Preprotein translocase subunit SecA (ATPase, RNA helicase)	822
648913193	370	57.72	2	363	1	368	0.0e+00	525	COG0082	Chorismate synthase	369
648913195	304	32.25	6	304	17	261	1.0e-47	183	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
648913196	205	24.47	14	195	1	173	5.0e-19	87.7	COG3545	Predicted esterase of the alpha/beta hydrolase fold	181
648913197	833	42.08	110	833	2	710	0.0e+00	638	COG2217	Cation transport ATPase	713
648913198	393	51.06	14	389	1	354	7.0e-114	404	COG2262	50S ribosomal subunit-associated GTPase HflX	411
648913199	256	43.78	6	215	24	239	1.0e-55	209	COG0688	Phosphatidylserine decarboxylase	239
648913202	365	35.86	5	364	16	396	2.0e-67	250	COG3213	Uncharacterized protein involved in response to NO	396
648913203	204	64.22	1	204	1	204	4.0e-58	217	COG4300	Cadmium resistance protein CadD, predicted permease	205
648913204	230	36.07	1	206	3	220	2.0e-39	155	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
648913205	265	25.81	21	265	9	255	1.0e-29	123	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
648913207	323	23.24	1	319	3	316	1.0e-20	94.1	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
648913208	462	66.88	1	462	1	462	0.0e+00	772	COG0114	Fumarate hydratase class II	462
648913209	236	47.26	1	236	4	235	7.0e-47	180	COG3471	Predicted secreted (periplasmic) protein	235
648913210	469	27.92	1	239	1	225	4.0e-40	159	COG0569	Trk K+ transport system, NAD-binding component	225
648913212	483	39.03	10	482	9	461	4.0e-57	215	COG0471	Di- and tricarboxylate transporter	461
648913213	417	44.33	18	410	24	416	4.0e-112	398	COG1894	NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F)	424
648913214	543	41.42	87	487	7	395	3.0e-80	293	COG0029	Aspartate oxidase	518
648913216	252	23.45	45	244	79	302	1.0e-22	99	COG0501	Zn-dependent protease with chaperone function	302
648913218	424	67.8	9	421	1	408	0.0e+00	668	COG1219	ATP-dependent protease Clp, ATPase subunit	408
648913219	861	78.47	1	861	1	852	0.0e+00	1498	COG1049	Aconitase B	852
648913220	1105	16.12	516	1105	203	768	5.0e-16	80.7	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
648913224	146	30	9	138	9	137	3.0e-17	81.1	COG3154	Predicted lipid carrier protein YhbT, SCP2 domain	168
648913225	302	26.33	2	290	1	299	7.0e-44	171	COG0826	Collagenase-like protease, PrtC family	347
648913226	335	37.87	3	335	5	312	4.0e-78	285	COG0826	Collagenase-like protease, PrtC family	347
648913227	661	70.86	1	651	17	664	0.0e+00	818	COG4389	Site-specific recombinase	677
648913231	642	43.98	1	522	3	530	0.0e+00	533	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
648913232	309	32.81	7	309	1	315	5.0e-62	231	COG0523	GTPase, G3E family	323
648913233	173	22.93	17	173	1	141	3.0e-22	98.1	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
648913234	275	61.09	3	240	9	246	5.0e-89	320	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
648913235	153	36.81	11	153	7	147	4.0e-29	120	COG3909	Cytochrome c556	147
648913236	424	56.37	1	423	13	421	0.0e+00	563	COG0281	Malic enzyme	432
648913237	211	49.04	1	207	1	208	6.0e-61	227	COG0125	Thymidylate kinase	208
648913238	331	38.82	1	331	4	340	1.0e-95	343	COG1559	Cell division protein YceG, involved in septum cleavage	342
648913241	830	46.78	1	823	4	667	0.0e+00	817	COG0272	NAD-dependent DNA ligase	667
648913242	344	24.44	1	273	22	327	2.0e-21	96.9	COG3049	Penicillin V acylase or related amidase, Ntn superfamily	353
648913244	290	61.54	1	284	1	285	2.0e-123	435	COG1210	UTP-glucose-1-phosphate uridylyltransferase	291
648913245	485	38.7	6	485	5	488	2.0e-87	316	COG0168	Trk-type K+ transport system, membrane component	499
648913246	91	35.29	1	85	1	72	2.0e-17	80.3	COG0254	Ribosomal protein L31	75
648913248	163	46.41	9	160	1	151	6.0e-35	140	COG0782	Transcription elongation factor, GreA/GreB family	151
648913249	513	50.91	1	488	4	469	0.0e+00	594	COG0034	Glutamine phosphoribosylpyrophosphate amidotransferase	470
648913250	172	26.92	1	154	1	156	2.0e-16	78.4	COG1286	Uncharacterized membrane protein, required for colicin V production	182
648913252	425	43.85	1	424	4	421	2.0e-123	435	COG0285	Folylpolyglutamate synthase/Dihydropteroate synthase	427
648913255	242	67.92	1	240	2	240	3.0e-113	401	COG1126	ABC-type polar amino acid transport system, ATPase component	240
648913256	259	51.19	5	254	3	254	5.0e-84	304	COG0030	16S rRNA A1518 and A1519 N6-dimethyltransferase RsmA/KsgA/DIM1 (may also have DNA glycosylase/AP lyase activity)	259
648913257	198	48.96	1	191	3	188	1.0e-62	232	COG0424	Predicted house-cleaning NTP pyrophosphatase, Maf/HAM1 superfamily	193
648913259	178	42.61	1	176	1	169	7.0e-55	206	COG0663	Carbonic anhydrase or acetyltransferase, isoleucine patch superfamily	176
648913260	459	63.3	5	459	4	458	0.0e+00	662	COG0165	Argininosuccinate lyase	459
648913262	248	43.15	7	247	10	222	4.0e-50	191	COG0765	ABC-type amino acid transport system, permease component	222
648913264	450	42.5	1	398	4	346	7.0e-105	374	COG0826	Collagenase-like protease, PrtC family	347
648913266	245	60.41	1	245	1	245	8.0e-101	359	COG1135	ABC-type methionine transport system, ATPase component	339
648913267	228	54.93	16	228	10	222	2.0e-64	238	COG2011	ABC-type methionine transport system, permease component	222
648913269	305	46.26	6	283	4	267	9.0e-77	280	COG1464	ABC-type metal ion transport system, periplasmic component/surface antigen	268
648913273	271	35.87	1	269	1	275	7.0e-41	160	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
648913274	431	57.57	1	431	1	428	0.0e+00	581	COG0172	Seryl-tRNA synthetase	429
648913275	794	51.08	4	790	3	736	0.0e+00	766	COG0574	Phosphoenolpyruvate synthase/pyruvate phosphate dikinase	740
648913276	273	47.64	5	273	4	272	2.0e-85	309	COG1806	Regulator of PEP synthase PpsR, kinase-PPPase family (combines ADP:protein kinase and phosphorylase activities)	273
648913278	566	44.14	36	535	1	477	5.0e-114	405	COG0608	Single-stranded DNA-specific exonuclease, DHH superfamily, may be involved in archaeal DNA replication intiation	491
648913282	184	50.87	8	175	15	187	2.0e-54	205	COG3028	Ribosomal 50S subunit-associated protein YjgA (function unknown), DUF615 family	187
648913283	443	35.6	12	443	3	454	9.0e-93	334	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
648913284	290	43.26	10	289	8	288	7.0e-65	241	COG1562	Phytoene/squalene synthetase	288
648913285	440	31.46	6	433	8	444	3.0e-77	282	COG2907	Predicted NAD/FAD-binding protein	447
648913286	180	23.95	1	165	8	170	2.0e-08	52	COG1714	Uncharacterized membrane protein YckC, RDD family	172
648913287	249	28.16	3	214	16	248	7.0e-18	84.5	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
648913290	1298	36.28	162	992	1	743	0.0e+00	747	COG0046	Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain	743
648913291	112	73.21	1	112	1	112	1.0e-38	151	COG0347	Nitrogen regulatory protein PII	112
648913292	1277	21.95	866	1257	2	388	3.0e-46	181	COG0247	Fe-S oxidoreductase	388
648913293	344	66.57	1	343	2	344	0.0e+00	534	COG0418	Dihydroorotase	344
648913295	73	39.73	2	73	5	77	2.0e-17	80.7	COG0425	TusA-related sulfurtransferase	78
648913297	139	42.34	1	110	1	111	3.0e-23	100	COG0789	DNA-binding transcriptional regulator, MerR family	124
648913298	374	21.96	2	374	3	354	2.0e-31	130	COG3203	Outer membrane protein (porin)	354
648913301	144	27.83	30	144	1	104	1.0e-07	49.5	COG4575	Membrane-anchored ribosome-binding protein, inhibits growth in stationary phase, ElaB/YqjD/DUF883 family	104
648913302	296	72.54	1	294	1	293	7.0e-121	426	COG0074	Succinyl-CoA synthetase, alpha subunit	293
648913303	388	60.67	1	388	1	386	0.0e+00	515	COG0045	Succinyl-CoA synthetase, beta subunit	387
648913305	477	48.93	1	467	2	454	0.0e+00	496	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
648913307	393	52.1	1	392	1	404	2.0e-112	399	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
648913308	946	56.66	8	946	1	906	0.0e+00	1300	COG0567	2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes	906
648913309	428	53.02	32	428	4	390	0.0e+00	487	COG0372	Citrate synthase	390
648913310	82	41.98	1	81	7	87	7.0e-17	78.7	COG2938	Succinate dehydrogenase flavin-adding protein, antitoxin component of the CptAB toxin-antitoxin module	94
648913311	242	54.24	9	242	1	232	2.0e-81	295	COG0479	Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit	234
648913312	587	53.38	5	573	4	562	0.0e+00	643	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
648913313	113	41.23	1	113	2	115	8.0e-20	89.1	COG2142	Succinate dehydrogenase, hydrophobic anchor subunit	117
648913314	125	40.94	4	125	1	127	1.0e-12	65.3	COG2009	Succinate dehydrogenase/fumarate reductase, cytochrome b subunit	132
648913315	123	44.21	22	115	15	107	6.0e-16	76.5	COG3339	Uncharacterized membrane protein YkvA, DUF1232 family	116
648913317	310	60.93	3	303	1	300	7.0e-119	420	COG0031	Cysteine synthase	300
648913319	282	51.07	4	282	1	272	6.0e-91	327	COG0253	Diaminopimelate epimerase	272
648913321	351	44.87	10	349	5	335	1.0e-90	326	COG1477	Thiamine biosynthesis lipoprotein ApbE	337
648913322	71	59.15	1	71	1	71	2.0e-23	100	COG2991	Uncharacterized protein	77
648913323	329	52.55	1	325	10	342	5.0e-104	371	COG1702	Phosphate starvation-inducible protein PhoH, predicted ATPase	348
648913325	262	36.03	2	262	25	296	4.0e-56	211	COG4558	ABC-type hemin transport system, periplasmic component	300
648913326	313	42.96	30	312	42	332	2.0e-40	160	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
648913327	248	38.4	10	245	1	250	3.0e-55	208	COG1120	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	258
648913328	606	28.61	55	423	37	410	5.0e-64	239	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
648913330	1045	14.72	409	1045	178	768	4.0e-13	71.1	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
648913335	526	67.3	4	526	2	515	0.0e+00	789	COG0138	AICAR transformylase/IMP cyclohydrolase PurH	515
648913336	291	21.64	18	281	31	285	1.0e-10	61.1	COG5006	Threonine/homoserine efflux transporter RhtA	292
648913339	80	54.17	7	78	27	98	3.0e-22	96.6	COG2901	DNA-binding protein Fis (factor for inversion stimulation)	98
648913340	230	35.27	26	230	3	207	5.0e-29	121	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
648913341	332	43.38	1	322	2	323	1.0e-85	310	COG0042	tRNA-dihydrouridine synthase	323
648913342	217	32.02	1	199	7	204	2.0e-18	85.8	COG1994	Zn-dependent protease (includes SpoIVFB)	230
648913343	288	43.62	4	97	6	99	4.0e-29	122	COG3615	Uncharacterized protein/domain, possibly involved in tellurite resistance	99
648913344	145	62.94	2	141	1	143	1.0e-49	188	COG0328	Ribonuclease HI	154
648913345	132	27.86	1	131	1	137	4.0e-16	77	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
648913346	396	37.5	57	360	10	313	1.0e-75	277	COG1619	Muramoyltetrapeptide carboxypeptidase LdcA (peptidoglycan recycling)	313
648913347	371	63.11	4	369	1	365	0.0e+00	560	COG0343	Queuine/archaeosine tRNA-ribosyltransferase	372
648913351	208	50.48	1	208	17	224	6.0e-44	170	COG1272	Predicted membrane channel-forming protein YqfA, hemolysin III family	226
648913352	186	49.42	10	181	5	176	8.0e-44	170	COG0503	Adenine/guanine phosphoribosyltransferase or related PRPP-binding protein	179
648913354	205	53.68	4	193	1	189	6.0e-67	246	COG0194	Guanylate kinase	191
648913355	68	52.17	1	68	1	69	8.0e-13	65.3	COG1758	DNA-directed RNA polymerase, subunit K/omega	74
648913356	718	43.96	15	718	7	701	0.0e+00	807	COG0317	(p)ppGpp synthase/hydrolase, HD superfamily	701
648913357	70	62.5	1	64	1	64	4.0e-06	43.3	COG0828	Ribosomal protein S21	67
648913358	148	59.46	1	147	1	148	1.0e-37	148	COG1610	Uncharacterized conserved protein YqeY	148
648913359	591	40.24	1	591	1	565	0.0e+00	482	COG0358	DNA primase (bacterial type)	568
648913360	648	49.55	308	642	9	342	7.0e-92	331	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
648913361	360	51.45	87	360	2	277	4.0e-92	331	COG0077	Prephenate dehydratase	279
648913362	508	57.67	185	505	1	325	6.0e-111	394	COG0280	Phosphotransacetylase	327
648913365	341	40.06	2	340	1	334	5.0e-77	281	COG0859	ADP-heptose:LPS heptosyltransferase	334
648913366	419	56.59	4	419	1	417	0.0e+00	566	COG0014	Gamma-glutamyl phosphate reductase	417
648913367	428	52.13	1	418	7	413	0.0e+00	530	COG2895	Sulfate adenylyltransferase subunit 1, EFTu-like GTPase family	431
648913368	160	36.02	1	160	4	164	9.0e-33	132	COG2980	Outer membrane lipoprotein LptE/RlpB (LPS assembly)	178
648913369	333	35.85	13	329	13	328	3.0e-56	212	COG1466	DNA polymerase III, delta subunit	334
648913371	239	29.96	4	228	3	222	5.0e-28	118	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
648913372	451	72.16	3	451	1	445	0.0e+00	603	COG2848	Uncharacterized conserved protein, UPF0210 family	445
648913373	90	58.89	1	90	1	90	5.0e-26	109	COG3830	ACT domain, binds amino acids and other small ligands	90
648913374	352	50.7	1	350	2	358	4.0e-115	408	COG0787	Alanine racemase	360
648913375	154	43.14	1	153	3	154	2.0e-33	134	COG1522	DNA-binding transcriptional regulator, Lrp family	154
648913380	751	56.74	3	751	1	714	0.0e+00	830	COG3256	Nitric oxide reductase large subunit	717
648913381	384	21.75	65	349	95	424	5.0e-20	92.5	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
648913382	251	28.31	19	250	49	311	2.0e-34	139	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
648913383	89	57.3	1	89	1	89	3.0e-28	116	COG0184	Ribosomal protein S15P/S13E	89
648913384	291	60.55	1	289	1	288	5.0e-123	433	COG0777	Acetyl-CoA carboxylase beta subunit	294
648913385	263	50.57	1	262	1	265	7.0e-84	303	COG0159	Tryptophan synthase alpha chain	265
648913386	159	31.06	1	159	2	156	1.0e-22	99.5	COG3030	Protein affecting phage T7 exclusion by the F plasmid, UPF0716 family	158
648913388	188	40.31	3	188	2	181	8.0e-60	223	COG0717	Deoxycytidine triphosphate deaminase	183
648913389	138	32.8	13	133	17	138	2.0e-17	81.1	COG4642	Uncharacterized conserved protein	139
648913390	299	42.19	1	299	1	301	1.0e-98	353	COG2974	DNA recombination-dependent growth factor C	303
648913394	388	44.64	1	388	2	393	7.0e-127	447	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
648913395	397	61.87	2	397	1	396	0.0e+00	628	COG1448	Aspartate/tyrosine/aromatic aminotransferase	396
648913396	405	39.41	1	400	7	380	8.0e-88	317	COG1488	Nicotinic acid phosphoribosyltransferase	405
648913397	287	43.32	44	283	1	247	3.0e-50	192	COG1354	Chromatin segregation and condensation protein Rec8/ScpA/Scc1, kleisin family	248
648913398	270	53.26	2	257	3	258	7.0e-90	323	COG1179	tRNA A37 threonylcarbamoyladenosine dehydratase	263
648913399	155	37.42	1	151	4	154	3.0e-18	84.6	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
648913400	227	29.29	22	208	5	189	5.0e-20	91.5	COG1525	Endonuclease YncB, thermonuclease family	192
648913401	223	54.02	3	218	2	225	1.0e-70	259	COG0120	Ribose 5-phosphate isomerase	227
648913402	162	64.78	3	161	1	159	3.0e-62	230	COG0245	2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	159
648913404	228	45.26	1	226	1	227	1.0e-55	209	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	230
648913405	240	35.5	4	232	14	238	4.0e-38	151	COG0847	DNA polymerase III, epsilon subunit or related 3'-5' exonuclease	243
648913407	227	37.45	1	226	3	234	1.0e-53	203	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
648913409	454	45.01	5	454	3	434	1.0e-105	377	COG0733	Na+-dependent transporter, SNF family	439
648913411	436	41.31	1	436	1	441	9.0e-96	344	COG0544	FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)	441
648913412	206	70.35	8	206	2	198	4.0e-87	314	COG0740	ATP-dependent protease ClpP, protease subunit	200
648913413	961	27.06	59	513	38	470	1.0e-09	59.6	COG2931	Ca2+-binding protein, RTX toxin-related	510
648913414	945	61.98	445	945	3	507	0.0e+00	665	COG0532	Translation initiation factor IF-2, a GTPase	509
648913415	500	54.04	163	359	1	190	2.0e-46	180	COG0195	Transcription antitermination factor NusA, contains S1 and KH domains	190
648913416	157	47.97	13	155	6	153	4.0e-41	160	COG0779	Ribosome maturation factor RimP	153
648913417	368	50.27	6	368	6	365	0.0e+00	460	COG1932	Phosphoserine aminotransferase	365
648913418	185	26.6	1	185	3	204	9.0e-22	97	COG0778	Nitroreductase	207
648913419	293	26.84	2	291	1	308	9.0e-39	154	COG0524	Sugar or nucleoside kinase, ribokinase family	311
648913420	441	19.8	11	419	16	384	2.0e-12	67.2	COG2814	Predicted arabinose efflux permease, MFS family	394
648913422	100	44.68	2	95	1	93	5.0e-26	109	COG0776	Bacterial nucleoid DNA-binding protein	94
648913423	787	43.03	144	786	1	650	0.0e+00	655	COG0072	Phenylalanyl-tRNA synthetase beta subunit	650
648913425	357	36.14	47	357	1	324	2.0e-65	242	COG0270	Site-specific DNA-cytosine methylase	328
648913426	139	37.93	1	115	2	115	2.0e-23	101	COG3727	G:T-mismatch repair DNA endonuclease, very short patch repair protein	150
648913427	330	54.19	1	327	3	335	1.0e-126	446	COG0016	Phenylalanyl-tRNA synthetase alpha subunit	335
648913428	119	79.66	1	118	1	118	5.0e-40	156	COG0292	Ribosomal protein L20	118
648913429	86	61.54	22	86	1	65	8.0e-16	75.3	COG0291	Ribosomal protein L35	65
648913430	155	69.03	1	155	21	175	1.0e-59	221	COG0290	Translation initiation factor IF-3	176
648913431	648	54.58	45	643	1	582	0.0e+00	786	COG0441	Threonyl-tRNA synthetase	589
648913434	827	47.78	15	816	1	750	0.0e+00	825	COG0058	Glucan phosphorylase	750
648913435	660	47.21	7	658	11	691	0.0e+00	714	COG1523	Pullulanase/glycogen debranching enzyme	697
648913436	1441	55.7	806	1427	1	627	0.0e+00	778	COG0296	1,4-alpha-glucan branching enzyme	628
648913437	159	43.37	1	159	1	163	2.0e-35	141	COG1047	FKBP-type peptidyl-prolyl cis-trans isomerase 2	174
648913439	457	37.84	31	457	25	457	2.0e-94	339	COG0277	FAD/FMN-containing dehydrogenase	459
648913440	670	56.11	51	636	7	624	0.0e+00	570	COG1297	Uncharacterized membrane protein, oligopeptide transporter (OPT) family	624
648913442	290	33.33	3	290	10	271	6.0e-39	154	COG1512	Uncharacterized membrane protein YgcG, contains a TPM-fold domain	271
648913443	196	51.3	2	194	1	185	4.0e-57	214	COG1704	Uncharacterized conserved protein	185
648913446	196	28.72	6	193	14	181	6.0e-22	97.5	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
648913447	289	36.86	39	282	42	293	2.0e-57	215	COG2333	Metal-dependent hydrolase, beta-lactamase superfamily II	293
648913448	459	34.22	13	459	21	469	1.0e-73	270	COG1757	Na+/H+ antiporter NhaC	485
648913450	299	40.69	11	298	2	279	1.0e-54	207	COG2890	Methylase of polypeptide chain release factors	280
648913451	265	27.13	69	252	43	230	1.0e-28	120	COG2849	Antitoxin component YwqK of the YwqJK toxin-antitoxin module	230
648913454	448	27.61	35	445	32	412	2.0e-60	226	COG0232	dGTP triphosphohydrolase	412
648913455	419	72.08	1	419	4	421	0.0e+00	720	COG1158	Transcription termination factor Rho	422
648913456	563	32.26	21	538	1	472	4.0e-100	358	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
648913457	206	28.44	1	203	1	205	1.0e-22	99.9	COG0625	Glutathione S-transferase	211
648913458	255	34.44	2	242	15	253	7.0e-56	210	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
648913459	238	27.75	10	236	2	223	8.0e-30	124	COG1802	DNA-binding transcriptional regulator, GntR family	230
648913460	138	46.32	1	136	2	136	7.0e-33	132	COG1765	Uncharacterized OsmC-related protein	137
648913461	270	54.58	10	270	7	263	5.0e-95	340	COG0351	Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase	263
648913463	790	20.8	1	790	10	768	4.0e-49	190	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
648913464	205	56.61	4	189	8	196	9.0e-57	213	COG3230	Heme oxygenase	196
648913465	249	34.54	15	247	38	285	2.0e-44	172	COG3176	Putative hemolysin	292
648913466	266	28.11	22	200	1	183	3.0e-23	102	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
648913467	135	23.4	1	125	1	138	1.0e-13	69.1	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
648913468	513	64.11	2	366	1	356	5.0e-125	441	COG3288	NAD/NADP transhydrogenase alpha subunit	356
648913469	127	56.69	1	127	1	124	1.0e-32	131	COG3686	Uncharacterized conserved protein, MAPEG superfamily	125
648913470	133	36.72	3	126	6	132	2.0e-17	81.2	COG3791	Uncharacterized conserved protein	133
648913473	461	57.05	1	459	1	463	0.0e+00	626	COG1282	NAD/NADP transhydrogenase beta subunit	463
648913475	228	35.48	14	228	3	217	2.0e-42	166	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
648913476	319	46	1	299	2	296	1.0e-74	273	COG1230	Co/Zn/Cd efflux system component	296
648913477	276	57.25	6	267	6	267	3.0e-101	361	COG2833	Uncharacterized conserved protein, contains ferritin-like DUF455 domain	268
648913479	206	37.98	1	206	3	210	5.0e-36	144	COG2834	Outer membrane lipoprotein-sorting protein	211
648913480	362	30.05	3	353	84	432	5.0e-77	281	COG2265	tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family	432
648913481	329	30.77	1	326	18	348	4.0e-58	218	COG0252	L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D	351
648913482	230	28.79	1	198	7	203	1.0e-33	136	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
648913483	446	46.62	1	442	5	458	3.0e-116	412	COG1109	Phosphomannomutase	464
648913484	287	47.92	18	279	8	264	2.0e-72	266	COG0294	Dihydropteroate synthase	274
648913485	397	57.32	1	396	1	396	0.0e+00	595	COG1448	Aspartate/tyrosine/aromatic aminotransferase	396
648913487	290	53.6	163	287	3	126	3.0e-26	112	COG3245	Cytochrome c5	126
648913488	292	31.01	33	288	1	247	1.0e-44	173	COG2876	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase	286
648913489	705	18.86	19	702	11	645	5.0e-42	166	COG2982	Uncharacterized protein involved in outer membrane biogenesis	648
648913490	300	39.66	6	295	4	293	4.0e-40	158	COG0583	DNA-binding transcriptional regulator, LysR family	297
648913491	196	37.25	1	194	1	189	5.0e-39	154	COG2249	Putative NADPH-quinone reductase (modulator of drug activity B)	189
648913492	174	35.87	1	174	2	180	3.0e-21	95	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
648913493	492	57.93	1	492	1	475	0.0e+00	675	COG0043	3-polyprenyl-4-hydroxybenzoate decarboxylase	477
648913497	412	40.87	3	410	1	412	2.0e-113	402	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
648913498	242	41.43	1	241	4	250	8.0e-42	163	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
648913499	167	33.33	6	155	7	152	2.0e-31	128	COG4706	Predicted 3-hydroxylacyl-ACP dehydratase, HotDog domain	161
648913502	305	35.65	1	305	5	318	5.0e-68	251	COG2334	Ser/Thr protein kinase RdoA involved in Cpx stress response, MazF antagonist	331
648913504	395	44.48	24	357	11	344	7.0e-85	308	COG1566	Multidrug resistance efflux pump	352
648913505	481	27.29	35	479	4	445	2.0e-45	177	COG1538	Outer membrane protein TolC	457
648913506	164	27.59	48	163	15	125	5.0e-10	57.6	COG1846	DNA-binding transcriptional regulator, MarR family	126
648913507	157	58.39	3	151	1	149	9.0e-54	202	COG0780	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF, C-terminal domain, T-fold superfamily	149
648913508	228	42.99	1	215	14	233	8.0e-42	163	COG1738	Uncharacterized PurR-regulated membrane protein YhhQ, DUF165 family	233
648913509	394	33.33	6	394	4	384	7.0e-70	258	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
648913510	90	70.45	1	88	1	87	1.0e-30	124	COG0211	Ribosomal protein L27	87
648913511	102	59.8	1	102	1	102	3.0e-32	129	COG0261	Ribosomal protein L21	103
648913512	324	38.89	8	324	3	322	2.0e-80	292	COG0142	Geranylgeranyl pyrophosphate synthase	322
648913513	148	58.5	3	148	2	148	7.0e-30	123	COG2707	Uncharacterized membrane protein, DUF441 family	151
648913515	51	59.18	1	49	2	50	7.0e-10	55.6	COG0267	Ribosomal protein L33	50
648913516	77	71.43	1	76	1	77	9.0e-22	95	COG0227	Ribosomal protein L28	77
648913517	440	40.74	197	410	57	270	2.0e-40	160	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
648913518	327	38.37	1	327	1	318	4.0e-51	195	COG4255	Uncharacterized protein	318
648913519	224	39.27	25	215	1	190	8.0e-36	143	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
648913521	308	48.7	1	306	1	302	2.0e-90	326	COG0196	FAD synthase	304
648913522	930	49.16	2	922	1	931	0.0e+00	1177	COG0060	Isoleucyl-tRNA synthetase	933
648913523	389	40.93	8	389	2	387	1.0e-129	456	COG2956	Lipopolysaccharide biosynthesis regulator YciM, contains six TPR domains and a predicted metal-binding C-terminal domain	389
648913524	131	46.15	24	101	22	98	1.0e-11	61.8	COG5416	Uncharacterized integral membrane protein	98
648913525	587	55.37	1	586	178	769	0.0e+00	731	COG4230	Delta 1-pyrroline-5-carboxylate dehydrogenase	769
648913526	609	43.81	24	439	1	391	2.0e-106	380	COG0506	Proline dehydrogenase	391
648913527	508	49.2	1	496	2	493	2.0e-88	320	COG0591	Na+/proline symporter	493
648913543	479	49.39	1	478	1	480	0.0e+00	525	COG0297	Glycogen synthase	487
648913544	436	49.52	14	426	2	391	0.0e+00	514	COG0448	ADP-glucose pyrophosphorylase	393
648913545	470	33.11	1	436	8	446	2.0e-80	293	COG2027	D-alanyl-D-alanine carboxypeptidase	470
648913546	240	38.22	12	235	2	217	1.0e-33	136	COG3201	Nicotinamide riboside transporter PnuC	222
648913547	188	29.89	3	179	1	175	5.0e-28	117	COG0431	NAD(P)H-dependent FMN reductase	184
648913549	252	26.47	22	250	2	235	5.0e-19	88.1	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
648913551	83	25	1	80	1	80	5.0e-07	46.1	COG0236	Acyl carrier protein	80
648913552	144	47.65	4	144	45	193	4.0e-34	137	COG4648	Uncharacterized membrane protein	201
648913554	584	23.44	23	456	41	511	7.0e-28	119	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
648913556	145	33.91	9	122	6	118	2.0e-21	95.3	COG0824	Acyl-CoA thioesterase FadM	137
648913557	196	22.45	1	190	5	194	8.0e-07	47.3	COG2834	Outer membrane lipoprotein-sorting protein	211
648913560	81	26.92	1	77	6	83	1.0e-08	51.5	COG2388	Predicted acetyltransferase, GNAT superfamily	99
648913561	385	21.07	9	382	3	319	1.0e-38	154	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
648913564	304	37.33	1	288	4	288	4.0e-67	248	COG1131	ABC-type multidrug transport system, ATPase component	293
648913565	406	24.64	191	399	78	282	2.0e-13	70.3	COG0842	ABC-type multidrug transport system, permease component	286
648913573	442	51.47	1	441	2	437	0.0e+00	547	COG0621	tRNA A37 methylthiotransferase MiaB	437
648913575	428	60.98	2	428	4	431	0.0e+00	585	COG0001	Glutamate-1-semialdehyde aminotransferase	432
648913576	737	51.53	21	737	12	701	0.0e+00	822	COG0317	(p)ppGpp synthase/hydrolase, HD superfamily	701
648913577	216	58.8	1	216	1	215	2.0e-85	308	COG2999	Glutaredoxin 2	215
648913578	299	32.76	8	299	4	292	4.0e-49	188	COG2962	Uncharacterized membrane protein RarD, contains two EamA domains	293
648913579	456	43.01	1	446	28	479	3.0e-113	402	COG0513	Superfamily II DNA and RNA helicase	513
648913580	258	31.15	1	241	2	241	9.0e-43	167	COG2186	DNA-binding transcriptional regulator, FadR family	241
648913583	479	40.71	16	467	1	446	7.0e-78	284	COG1538	Outer membrane protein TolC	457
648913584	1077	49.14	1	1039	2	1009	0.0e+00	990	COG0841	Multidrug efflux pump subunit AcrB	1009
648913585	404	38.89	13	368	24	372	5.0e-32	132	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
648913587	212	23.3	1	206	3	201	4.0e-15	74.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
648913588	172	46.3	8	169	1	160	6.0e-58	216	COG3265	Gluconate kinase	161
648913589	461	42.89	12	461	2	442	2.0e-85	310	COG2610	H+/gluconate symporter or related permease	442
648913590	177	41.72	8	167	2	160	1.0e-33	136	COG0597	Lipoprotein signal peptidase	167
648913591	322	66.67	3	296	1	294	3.0e-123	435	COG0761	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH	294
648913592	295	39.87	2	292	3	308	2.0e-52	199	COG0524	Sugar or nucleoside kinase, ribokinase family	311
648913593	290	56.67	1	286	1	300	4.0e-86	311	COG2354	Uncharacterized membrane protein MutK, may be involved in DNA repair	303
648913594	513	33.73	10	508	10	510	1.0e-94	340	COG0815	Apolipoprotein N-acyltransferase	518
648913595	287	39.78	12	284	64	335	1.0e-65	242	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
648913596	417	49.28	1	414	1	412	9.0e-122	430	COG0373	Glutamyl-tRNA reductase	414
648913597	314	18.69	15	313	1	293	4.0e-46	178	COG1518	CRISPR/Cas system-associated endonuclease Cas1	327
648913603	164	30.54	1	161	7	167	1.0e-12	66.2	COG1495	Disulfide bond formation protein DsbB	170
648913604	950	58.42	443	921	10	496	0.0e+00	708	COG1003	Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain	496
648913605	178	59.17	8	176	1	169	9.0e-65	239	COG1778	 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsC and related HAD superfamily phosphatases	170
648913606	193	32.29	1	192	2	186	2.0e-35	141	COG3117	Lipopolysaccharide export system protein LptC	188
648913607	174	41.32	9	174	12	168	3.0e-30	124	COG1934	Lipopolysaccharide export system protein LptA	173
648913608	244	68.88	6	244	3	243	5.0e-108	384	COG1137	ABC-type lipopolysaccharide export system, ATPase component	243
648913609	453	40.84	1	451	1	442	9.0e-112	397	COG1508	DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog	444
648913610	104	43.4	1	104	1	106	1.0e-17	81	COG1544	Ribosome-associated translation inhibitor RaiA	110
648913611	235	32.82	4	194	3	193	6.0e-36	144	COG0518	GMP synthase - Glutamine amidotransferase domain	198
648913612	236	32.35	1	236	3	226	4.0e-50	191	COG0313	16S rRNA C1402 (ribose-2'-O) methylase RsmI	275
648913613	196	39.18	4	196	2	192	1.0e-49	189	COG0424	Predicted house-cleaning NTP pyrophosphatase, Maf/HAM1 superfamily	193
648913614	165	29.94	1	165	4	175	4.0e-19	87.7	COG1399	Uncharacterized metal-binding protein YceD, DUF177 family	176
648913615	59	47.37	1	56	1	57	2.0e-12	64.1	COG0333	Ribosomal protein L32	57
648913616	175	30.61	1	174	1	192	4.0e-33	134	COG2236	Hypoxanthine phosphoribosyltransferase	192
648913617	355	48.66	1	335	1	336	1.0e-108	386	COG0416	Fatty acid/phospholipid biosynthesis enzyme	338
648913618	320	58.2	1	320	1	322	1.0e-119	423	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
648913620	308	53.72	1	307	2	310	2.0e-92	332	COG0331	Malonyl CoA-acyl carrier protein transacylase	310
648913621	616	33.33	18	608	4	560	6.0e-120	425	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
648913622	280	21.59	4	239	2	258	2.0e-23	103	COG1216	Glycosyltransferase, GT2 family	305
648913624	687	52.81	1	686	1	690	0.0e+00	830	COG0751	Glycyl-tRNA synthetase, beta subunit	691
648913627	248	49.8	5	246	2	251	4.0e-52	198	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
648913628	687	40.9	28	422	3	397	1.0e-63	238	COG0475	Kef-type K+ transport system, membrane component KefB	397
648913632	159	26.81	29	158	50	187	3.0e-09	54.8	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
648913633	303	73.91	1	299	4	298	0.0e+00	550	COG0752	Glycyl-tRNA synthetase, alpha subunit	298
648913634	241	42.04	1	239	3	246	5.0e-64	237	COG1385	16S rRNA U1498 N3-methylase RsmE	246
648913635	262	32.96	1	258	4	260	2.0e-52	199	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
648913636	156	47.68	4	153	2	151	1.0e-48	185	COG3012	Uncharacterized conserved protein YchJ, contains N- and C-terminal SEC-C domains	151
648913637	284	52.41	5	165	37	198	3.0e-46	178	COG2878	Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit	198
648913638	343	56.64	3	340	2	335	2.0e-125	442	COG0057	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase	335
648913639	378	61.26	1	378	1	370	0.0e+00	499	COG0484	DnaJ-class molecular chaperone with C-terminal Zn finger domain	371
648913640	878	51.93	3	878	1	814	0.0e+00	1064	COG0495	Leucyl-tRNA synthetase	814
648913645	595	32.86	35	450	7	387	7.0e-63	235	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
648913646	523	56.02	197	360	4	169	2.0e-68	253	COG0225	Peptide methionine sulfoxide reductase MsrA	174
648913647	528	34.77	1	528	4	517	5.0e-118	418	COG1620	L-lactate permease	522
648913648	900	47.49	6	900	1	910	0.0e+00	1067	COG2352	Phosphoenolpyruvate carboxylase	910
648913649	166	56.13	1	155	1	154	2.0e-51	195	COG0315	Molybdenum cofactor biosynthesis enzyme	157
648913650	249	47.22	1	246	3	253	2.0e-63	236	COG0476	Molybdopterin or thiamine biosynthesis adenylyltransferase	254
648913651	204	41.67	1	204	6	207	8.0e-52	197	COG0352	Thiamine monophosphate synthase	211
648913652	130	39.17	12	129	1	120	5.0e-17	80.2	COG0789	DNA-binding transcriptional regulator, MerR family	124
648913653	125	39.83	11	124	3	119	4.0e-16	77	COG0599	Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family	124
648913654	894	45.52	2	893	47	960	0.0e+00	996	COG1391	Glutamine synthetase adenylyltransferase	963
648913656	503	64.36	1	487	7	495	0.0e+00	753	COG0753	Catalase	496
648913657	735	42.43	12	655	1	652	0.0e+00	571	COG0210	Superfamily I DNA or RNA helicase	655
648913660	470	24.46	139	461	41	347	4.0e-41	162	COG3177	Fic family protein	348
648913661	135	24.19	5	125	4	126	4.0e-10	57.3	COG1765	Uncharacterized OsmC-related protein	137
648913664	678	57.27	1	676	7	683	0.0e+00	877	COG0339	Zn-dependent oligopeptidase	683
648913666	354	19.53	10	350	14	339	1.0e-10	61.1	COG0628	Predicted PurR-regulated permease PerM	355
648913667	521	26.3	3	516	10	532	3.0e-61	230	COG0659	Sulfate permease or related transporter, MFS superfamily	554
648913668	224	39.18	8	198	7	200	1.0e-49	189	COG0288	Carbonic anhydrase	207
648913669	413	39.47	1	408	4	415	2.0e-65	243	COG0814	Amino acid permease	415
648913671	355	22.31	11	355	6	377	3.0e-20	93.2	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
648913672	192	45.76	1	177	5	176	2.0e-51	195	COG0241	Histidinol phosphatase or a related phosphatase	181
648913673	244	30.77	6	233	1	228	4.0e-31	128	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
648913674	231	35.14	7	228	4	221	3.0e-43	168	COG1451	Predicted metal-dependent hydrolase	223
648913675	329	48.02	1	329	2	329	3.0e-108	385	COG0240	Glycerol-3-phosphate dehydrogenase	329
648913677	98	31.58	4	98	2	96	6.0e-14	69.2	COG3027	Cell division protein ZapA, inhibits GTPase activity of FtsZ	105
648913678	143	66.67	1	143	1	144	2.0e-54	204	COG0102	Ribosomal protein L13	148
648913679	130	60	1	130	1	130	9.0e-46	175	COG0103	Ribosomal protein S9	130
648913680	82	39.47	1	75	1	76	3.0e-06	43.5	COG2261	Uncharacterized membrane protein YeaQ/YmgE, transglycosylase-associated protein family	82
648913681	169	14.73	27	155	1	111	4.0e-06	44.5	COG0526	Thiol-disulfide isomerase or thioredoxin	127
648913682	145	29.2	26	138	12	124	4.0e-10	57.2	COG1846	DNA-binding transcriptional regulator, MarR family	126
648913683	166	28.12	9	166	6	163	1.0e-27	116	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
648913685	402	50.3	9	343	6	338	3.0e-90	325	COG0206	Cell division GTPase FtsZ	338
648913686	414	50.12	1	414	1	418	0.0e+00	462	COG0849	Cell division ATPase FtsA	418
648913687	237	31.38	3	233	35	269	2.0e-36	145	COG1589	Cell division septal protein FtsQ	269
648913688	303	43.35	3	300	1	316	1.0e-78	286	COG1181	D-alanine-D-alanine ligase and related ATP-grasp enzymes	317
648913689	469	52.02	1	468	2	459	0.0e+00	568	COG0773	UDP-N-acetylmuramate-alanine ligase	459
648913690	356	46.24	4	355	1	355	5.0e-94	338	COG0707	UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase	357
648913691	386	38.83	16	385	11	381	2.0e-84	306	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
648913692	445	45.09	1	445	3	446	0.0e+00	475	COG0771	UDP-N-acetylmuramoylalanine-D-glutamate ligase	448
648913693	360	41.94	26	360	6	316	5.0e-59	221	COG0472	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase	319
648913695	455	48.07	16	452	16	451	2.0e-126	446	COG0770	UDP-N-acetylmuramyl pentapeptide synthase	451
648913698	492	46.81	26	491	13	475	0.0e+00	486	COG0769	UDP-N-acetylmuramyl tripeptide synthase	475
648913699	581	38.77	17	570	6	599	1.0e-125	444	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
648913700	87	23.81	1	83	20	103	3.0e-06	43.7	COG3116	Cell division protein FtsL, interacts with FtsB, FtsL and FtsQ	105
648913701	323	54.49	5	313	3	313	6.0e-118	417	COG0275	16S rRNA C1402 N4-methylase RsmH	314
648913702	151	41.3	1	138	1	136	3.0e-35	140	COG2001	MraZ, DNA-binding transcriptional regulator and inhibitor of RsmH methyltransferase activity	146
648913703	383	40.64	18	377	2	370	1.0e-85	310	COG1565	SAM-dependent methyltransferase, MidA family	370
648913706	273	32.1	9	271	2	263	2.0e-45	175	COG2819	Predicted hydrolase of the alpha/beta superfamily	264
648913707	700	39.03	1	700	18	719	0.0e+00	661	COG4773	Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid	719
648913709	1144	46.11	3	1143	1	1139	0.0e+00	1243	COG0587	DNA polymerase III, alpha subunit	1139
648913710	77	53.42	2	74	1	73	2.0e-19	86.8	COG2501	Ribosome-associated protein YbcJ, S4-like RNA binding protein	73
648913712	278	44.36	1	256	3	255	2.0e-60	226	COG0613	Predicted metal-dependent phosphoesterase TrpH, contains PHP domain	258
648913713	168	64.81	1	162	1	161	2.0e-73	268	COG1854	S-ribosylhomocysteine lyase LuxS, autoinducer biosynthesis	161
648913714	107	50.94	2	105	1	106	1.0e-31	127	COG1965	Iron-binding protein CyaY, frataxin homolog	106
648913716	406	50.52	1	381	9	394	7.0e-121	427	COG0019	Diaminopimelate decarboxylase	394
648913717	75	42.86	6	75	5	72	4.0e-08	49.5	COG2900	Uncharacterized coiled-coil protein SlyX (sensitive to lysis X)	72
648913718	456	56.77	1	456	1	444	0.0e+00	523	COG2056	Predicted histidine transporter YuiF, NhaC family	444
648913722	274	43.82	5	268	12	274	3.0e-65	241	COG2890	Methylase of polypeptide chain release factors	280
648913723	304	24.42	23	304	2	300	6.0e-11	61.7	COG1721	Uncharacterized conserved protein, DUF58 family, contains vWF domain	416
648913724	302	41.48	1	300	11	321	7.0e-67	247	COG0714	MoxR-like ATPase	329
648913725	466	28.81	226	451	60	270	4.0e-18	86.3	COG0790	TPR repeat	292
648913726	295	39.3	6	289	2	279	1.0e-68	253	COG0287	Prephenate dehydrogenase	279
648913728	289	43.99	1	289	18	307	8.0e-81	293	COG1560	Lauroyl/myristoyl acyltransferase	308
648913729	182	58	11	160	1	150	3.0e-52	197	COG0817	Holliday junction resolvasome RuvABC endonuclease subunit	160
648913730	279	39.21	2	273	1	262	7.0e-54	204	COG0388	Predicted amidohydrolase	274
648913732	368	27.35	18	366	1	330	2.0e-46	180	COG0859	ADP-heptose:LPS heptosyltransferase	334
648913733	430	56.54	1	427	1	413	0.0e+00	617	COG3977	Alanine-alpha-ketoisovalerate (or valine-pyruvate) aminotransferase	417
648913734	1089	50.68	7	1089	1	1087	0.0e+00	1342	COG3513	CRISPR/Cas system Type II  associated protein, contains McrA/HNH and RuvC-like nuclease domains	1088
648913735	304	24.07	1	304	2	324	4.0e-52	198	COG1518	CRISPR/Cas system-associated endonuclease Cas1	327
648913736	108	76.85	1	108	1	108	4.0e-44	169	COG3512	CRISPR/Cas system-associated protein Cas2, endoribonuclease	116
648913739	329	36.18	1	319	5	351	4.0e-83	301	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
648913741	195	34.33	1	185	1	199	6.0e-38	150	COG0288	Carbonic anhydrase	207
648913742	202	44.33	1	202	2	196	6.0e-58	217	COG1057	Nicotinic acid mononucleotide adenylyltransferase	197
648913743	130	46.49	7	120	1	114	1.0e-30	125	COG0799	Ribosomal silencing factor RsfS, regulates association of 30S and 50S subunits	115
648913745	3852	20.94	3127	3852	8	715	2.0e-06	50.5	COG5295	Autotransporter adhesin	715
648913746	473	35.7	38	473	5	441	1.0e-59	224	COG0038	H+/Cl- antiporter ClcA	443
648913747	406	46.83	2	406	1	404	6.0e-130	457	COG1364	N-acetylglutamate synthase (N-acetylornithine aminotransferase)	404
648913749	221	33.7	35	209	18	197	3.0e-30	125	COG0791	Cell wall-associated hydrolase, NlpC family	197
648913750	547	34.73	9	517	4	514	8.0e-96	344	COG0661	Predicted unusual protein kinase regulating ubiquinone biosynthesis, AarF/ABC1/UbiB family	517
648913751	300	42.4	8	283	4	286	5.0e-77	281	COG1281	Redox-regulated molecular chaperone, HSP33 family	286
648913752	266	55	1	259	3	262	1.0e-100	359	COG1127	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, ATPase component MlaF	263
648913754	258	46.48	1	256	9	263	3.0e-62	231	COG0767	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, permease component MlaE	267
648913756	200	36.32	1	193	3	202	1.0e-43	169	COG2854	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic MlaC component	202
648913757	91	29.03	1	89	5	96	9.0e-14	68.3	COG3113	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, MlaB component, contains STAS domain	99
648913758	276	43.69	18	238	32	249	3.0e-65	241	COG2853	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, lipoprotein component MlaA	250
648913759	220	25.91	4	220	1	206	5.0e-30	124	COG0778	Nitroreductase	207
648913761	128	35.11	1	128	8	137	4.0e-25	106	COG0824	Acyl-CoA thioesterase FadM	137
648913762	162	25.64	21	162	3	154	6.0e-14	70.3	COG1225	Peroxiredoxin	157
648913763	383	58.09	1	376	1	361	0.0e+00	513	COG0536	GTPase involved in cell partioning and DNA repair	369
648913767	473	56.55	1	473	1	464	0.0e+00	673	COG0215	Cysteinyl-tRNA synthetase	464
648913768	72	53.42	1	71	1	73	1.0e-20	91.5	COG0254	Ribosomal protein L31	75
648913771	929	56.79	329	929	2	593	0.0e+00	768	COG0749	DNA polymerase I - 3'-5' exonuclease and polymerase domains	593
648913774	210	35.91	1	208	2	221	8.0e-45	173	COG2323	Uncharacterized membrane protein YcaP, DUF421 family	224
648913775	281	35.21	1	276	15	297	1.0e-37	150	COG0668	Small-conductance mechanosensitive channel	316
648913777	231	38.16	1	228	3	230	1.0e-47	183	COG1346	Putative effector of murein hydrolase	230
648913778	130	29.37	4	129	1	126	4.0e-19	87.1	COG1380	Putative effector of murein hydrolase LrgA, UPF0299 family	128
648913779	296	32.23	1	296	1	295	5.0e-35	141	COG0583	DNA-binding transcriptional regulator, LysR family	297
648913780	221	32.74	3	220	2	220	6.0e-38	151	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
648913781	752	48.9	1	749	1	767	0.0e+00	947	COG1554	Trehalose and maltose hydrolase (possible phosphorylase)	772
648913782	335	29.45	14	333	8	307	4.0e-47	182	COG2017	Galactose mutarotase or related enzyme	308
648913784	359	41.79	47	311	10	264	3.0e-60	225	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
648913785	319	45.51	6	315	1	310	8.0e-95	340	COG0039	Malate/lactate dehydrogenase	313
648913786	544	46.15	240	541	4	305	4.0e-77	282	COG0706	Membrane protein insertase Oxa1/YidC/SpoIIIJ, required for the localization of integral membrane proteins	314
648913787	72	61.43	3	72	5	74	9.0e-26	108	COG0759	Membrane-anchored protein YidD, putatitve component of membrane protein insertase Oxa1/YidC/SpoIIIJ	92
648913788	112	37.38	5	111	1	107	4.0e-17	79.9	COG0594	RNase P protein component	117
648913790	504	50.14	155	500	65	408	9.0e-118	417	COG0593	Chromosomal replication initiation ATPase DnaA	408
648913791	367	38.95	7	367	6	364	2.0e-88	319	COG0592	DNA polymerase III sliding clamp (beta) subunit, PCNA homolog	364
648913792	1306	23.52	289	1306	68	1036	9.0e-66	246	COG3419	Tfp pilus assembly protein, tip-associated adhesin PilY1	1036
648913794	371	31.17	1	368	2	334	9.0e-92	330	COG0136	Aspartate-semialdehyde dehydrogenase	334
648913796	154	19.7	15	140	2	131	4.0e-20	90.8	COG2913	Outer membrane protein assembly factor BamE, lipoprotein component of the BamABCDE complex	147
648913798	238	32.71	18	227	1	192	4.0e-31	128	COG0406	Broad specificity phosphatase PhoE	208
648913799	243	31.47	1	241	1	243	1.0e-28	120	COG3279	DNA-binding response regulator, LytR/AlgR family	244
648913801	226	37.44	9	216	3	219	4.0e-33	135	COG1214	tRNA A37 threonylcarbamoyladenosine modification protein TsaB	220
648913802	158	30.12	1	148	12	177	2.0e-19	88.5	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
648913803	265	27.61	124	265	39	201	7.0e-14	71.2	COG1573	Uracil-DNA glycosylase	202
648913805	496	37.79	45	478	1	422	5.0e-82	298	COG1322	DNA anti-recombination protein (rearrangement mutator) RmuC	448
648913806	187	35.06	14	187	4	177	1.0e-55	209	COG0634	Hypoxanthine-guanine phosphoribosyltransferase	178
648913807	152	28.68	1	134	1	134	2.0e-22	98	COG2893	Phosphotransferase system, mannose/fructose-specific component IIA	143
648913808	89	48.86	1	88	1	88	1.0e-24	104	COG1925	Phosphotransferase system, HPr and related phosphotransfer proteins	88
648913809	587	43.28	3	581	1	574	0.0e+00	633	COG1080	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria)	574
648913812	170	19.59	18	163	2	142	9.0e-26	109	COG2913	Outer membrane protein assembly factor BamE, lipoprotein component of the BamABCDE complex	147
648913813	183	24.86	10	181	10	187	2.0e-11	62.5	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
648913814	210	34.72	1	209	10	225	2.0e-28	119	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
648913817	120	44.87	6	83	3	77	4.0e-12	63.7	COG1314	Preprotein translocase subunit SecG	86
648913818	257	45.06	9	257	2	250	3.0e-72	265	COG0149	Triosephosphate isomerase	251
648913819	165	49.67	8	157	9	156	4.0e-47	180	COG1956	GAF domain-containing protein, putative methionine-R-sulfoxide reductase	163
648913820	218	40.3	6	205	1	201	3.0e-52	198	COG2518	Protein-L-isoaspartate O-methyltransferase	209
648913821	107	36.36	1	107	1	110	3.0e-18	83.4	COG0607	Rhodanese-related sulfurtransferase	110
648913822	324	45.26	1	324	1	322	3.0e-92	332	COG2896	Molybdenum cofactor biosynthesis enzyme MoaA	322
648913824	185	63.74	1	182	1	182	6.0e-83	299	COG1949	Oligoribonuclease (3'-5' exoribonuclease)	184
648913830	558	67.93	5	558	1	554	0.0e+00	895	COG2759	Formyltetrahydrofolate synthetase	554
648913831	143	50.71	3	142	1	140	2.0e-37	147	COG2510	Uncharacterized membrane protein	140
648913832	410	52.35	79	410	1	340	2.0e-112	399	COG0552	Signal recognition particle GTPase	340
648913833	454	53.73	3	454	2	454	0.0e+00	549	COG0486	tRNA U34 5-carboxymethylaminomethyl modifying GTPase MnmE/TrmE	454
648913834	86	46.25	7	86	1	79	1.0e-21	94.6	COG5007	Acid stress-induced BolA-like protein IbaG/YrbA, predicted regulator of iron metabolism	80
648913835	723	28.85	1	717	2	674	2.0e-104	373	COG1289	Uncharacterized membrane protein YccC	674
648913836	238	57.26	8	237	11	241	4.0e-84	304	COG2227	2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase	243
648913838	215	37.26	2	197	78	288	4.0e-44	171	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
648913839	190	39.25	1	185	1	185	3.0e-35	141	COG2119	Putative Ca2+/H+ antiporter, TMEM165/GDT1 family	190
648913841	347	66.86	5	346	3	349	0.0e+00	574	COG0722	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase	351
648913844	395	50.63	1	394	3	391	2.0e-106	379	COG0452	Phosphopantothenoylcysteine synthetase/decarboxylase	392
648913845	308	50.17	14	308	1	295	2.0e-104	372	COG1159	GTPase Era, involved in 16S rRNA processing	298
648913846	302	45.76	67	297	1	235	1.0e-63	237	COG0571	dsRNA-specific ribonuclease	235
648913847	107	61.68	1	107	1	105	4.0e-30	123	COG4859	Uncharacterized protein	105
648913848	159	44.97	1	145	1	149	7.0e-43	166	COG0054	6,7-dimethyl-8-ribityllumazine synthase (Riboflavin synthase beta chain)	152
648913849	142	41.1	1	139	6	151	1.0e-30	125	COG0781	Transcription termination factor NusB	151
648913850	208	21.2	16	199	10	193	2.0e-07	49.3	COG1309	DNA-binding transcriptional regulator, AcrR family	201
648913851	681	16.42	24	681	41	768	1.0e-29	125	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
648913854	432	32.36	58	429	144	489	5.0e-58	218	COG0286	Type I restriction-modification system, DNA methylase subunit	489
648913857	302	21.78	1	299	12	265	2.0e-22	99.6	COG0863	DNA modification methylase	302
648913858	871	23.88	18	768	1	738	3.0e-64	240	COG0610	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases ...	962
648913859	358	70.99	1	358	1	362	0.0e+00	559	COG0216	Protein chain release factor A	363
648913860	265	38.13	1	252	1	254	5.0e-61	228	COG0084	Tat protein secretion system quality control protein TatD (DNase activity)	256
648913861	425	19.8	49	346	34	317	2.0e-11	63.7	COG2814	Predicted arabinose efflux permease, MFS family	394
648913862	509	24.14	19	502	6	519	2.0e-32	133	COG0433	Archaeal DNA helicase HerA or a related bacterial ATPase, contains HAS-barrel and ATPase domains	520
648913863	757	62.05	423	754	1	330	5.0e-128	452	COG0620	Methionine synthase II (cobalamin-independent)	330
648913864	293	47.1	7	292	1	291	7.0e-83	300	COG0685	5,10-methylenetetrahydrofolate reductase	291
648913865	65	60	1	65	1	64	2.0e-19	87.3	COG2975	Fe-S-cluster formation regulator IscX/YfhJ	64
648913866	113	44.86	1	105	1	102	3.0e-17	80.5	COG0633	Ferredoxin	102
648913868	620	46.4	18	606	4	579	0.0e+00	549	COG0443	Molecular chaperone DnaK (HSP70)	579
648913869	789	54.19	1	785	10	791	0.0e+00	987	COG3957	Phosphoketolase	793
648913871	269	37.82	3	267	5	278	6.0e-67	247	COG0169	Shikimate 5-dehydrogenase	283
648913872	472	50.84	1	472	1	443	0.0e+00	525	COG0174	Glutamine synthetase	443
648913874	211	26.32	3	211	10	174	3.0e-06	45.4	COG5430	Spore coat protein U (SCPU) domain, function unknown	174
648913875	241	24.38	1	235	5	231	2.0e-23	102	COG3121	P pilus assembly protein, chaperone PapD	235
648913876	822	24.03	50	822	65	835	1.0e-95	344	COG3188	Outer membrane usher protein FimD/PapC	835
648913877	328	27.56	174	328	26	174	1.0e-10	60.8	COG5430	Spore coat protein U (SCPU) domain, function unknown	174
648913878	345	37.88	15	339	6	318	8.0e-80	290	COG0042	tRNA-dihydrouridine synthase	323
648913881	156	38.62	11	152	11	147	2.0e-25	108	COG3772	Phage-related lysozyme (muramidase), GH24 family	152
648913887	1227	32.39	3	898	2	897	0.0e+00	590	COG4733	Phage-related protein, tail component	952
648913888	240	40.93	1	182	5	195	2.0e-37	149	COG4723	Phage-related protein, tail component	198
648913889	251	38.28	5	123	3	130	2.0e-16	79.8	COG1310	Proteasome lid subunit RPN8/RPN11, contains Jab1/MPN domain metalloenzyme (JAMM) motif	134
648913890	229	50	2	229	8	231	1.0e-75	276	COG4672	Phage-related protein	231
648913891	110	37.27	1	110	2	111	1.0e-22	98.5	COG4718	Phage-related protein	111
648913900	520	26.96	30	520	16	489	1.0e-74	274	COG5511	Bacteriophage capsid protein	492
648913904	675	26.25	11	657	1	600	6.0e-72	265	COG5525	Phage terminase, large subunit GpA	611
648913905	163	20.81	1	162	5	174	8.0e-06	43.5	COG4220	Phage DNA packaging protein, Nu1 subunit of terminase	174
648913909	138	32.88	1	73	2	72	7.0e-08	49.6	COG1598	Predicted nuclease of the RNAse H fold, HicB family	73
648913912	233	30.22	11	230	1	210	2.0e-29	122	COG2932	Phage repressor protein C, contains Cro/C1-type HTH and peptisase s24 domains	214
648913918	285	53.45	5	279	6	264	7.0e-80	290	COG5532	Uncharacterized conserved protein YfdQ, DUF2303 family	269
648913925	692	42.16	32	684	1	574	0.0e+00	543	COG1966	Carbon starvation protein CstA	575
648913926	62	41.54	1	62	1	65	2.0e-13	67.2	COG2879	Uncharacterized short protein YbdD, DUF466 family	65
648913928	339	30.38	6	335	4	323	1.0e-55	210	COG1477	Thiamine biosynthesis lipoprotein ApbE	337
648913929	165	60.24	1	165	1	163	4.0e-62	230	COG4314	Nitrous oxide reductase accessory protein NosL	176
648913930	276	22.78	1	276	1	277	5.0e-15	75.2	COG1277	ABC-type transport system involved in multi-copper enzyme maturation, permease component	278
648913931	297	35.93	6	294	5	293	3.0e-63	235	COG1131	ABC-type multidrug transport system, ATPase component	293
648913932	358	60.31	1	318	81	400	6.0e-122	430	COG3420	Nitrous oxidase accessory protein NosD, contains tandem CASH domains	408
648913933	655	56.65	11	654	10	637	0.0e+00	793	COG4263	Nitrous oxide reductase	637
648913934	779	41.07	12	513	15	481	3.0e-118	419	COG3901	Regulator of nitric oxide reductase transcription	482
648913935	349	66.07	11	345	1	336	0.0e+00	542	COG0059	Ketol-acid reductoisomerase	338
648913936	97	44.44	1	81	1	81	2.0e-20	90.8	COG1359	Quinol monooxygenase YgiN	100
648913937	163	54.04	1	161	3	163	3.0e-48	184	COG0440	Acetolactate synthase, small subunit	163
648913938	592	50.53	2	563	1	549	0.0e+00	660	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
648913941	223	49.73	42	223	22	204	9.0e-43	167	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
648913942	217	50.93	4	215	1	214	6.0e-61	227	COG0040	ATP phosphoribosyltransferase	290
648913943	274	53.14	3	272	1	243	1.0e-63	236	COG3680	Uncharacterized protein	259
648913944	430	54.88	1	430	1	423	0.0e+00	564	COG0141	Histidinol dehydrogenase	425
648913945	280	34.57	10	273	16	268	1.0e-56	213	COG0656	Aldo/keto reductase, related to diketogulonate reductase	280
648913946	563	38.56	3	563	25	588	0.0e+00	502	COG4178	ABC-type uncharacterized transport system, permease and ATPase components	604
648913948	737	33.78	3	735	12	717	0.0e+00	469	COG4773	Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid	719
648913949	278	48.79	72	278	6	212	1.0e-56	213	COG0560	Phosphoserine phosphatase	212
648913950	602	65.05	1	595	1	585	0.0e+00	933	COG0173	Aspartyl-tRNA synthetase	585
648913951	229	48.11	10	220	1	210	4.0e-61	227	COG2928	Uncharacterized membrane protein	222
648913952	380	36.5	55	378	8	317	2.0e-88	319	COG2829	Outer membrane phospholipase A	317
648913953	87	62.07	1	87	1	87	1.0e-09	54.9	COG0268	Ribosomal protein S20	88
648913954	395	36.98	13	393	2	362	3.0e-76	278	COG0687	Spermidine/putrescine-binding periplasmic protein	363
648913955	233	54.19	4	227	1	226	2.0e-69	255	COG2908	UDP-2,3-diacylglucosamine pyrophosphatase LpxH	237
648913956	361	40.82	6	344	3	335	4.0e-76	278	COG1472	Periplasmic beta-glucosidase and related glycosidases	397
648913957	507	35.5	6	495	1	481	4.0e-74	272	COG1757	Na+/H+ antiporter NhaC	485
648913958	498	41.06	37	391	15	340	3.0e-68	253	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
648913959	210	55.77	1	208	1	208	2.0e-84	305	COG0177	Endonuclease III	211
648913960	311	58.03	3	306	1	305	4.0e-108	384	COG0181	Porphobilinogen deaminase	307
648913961	171	40.79	19	169	5	153	8.0e-38	150	COG0319	ssRNA-specific RNase YbeY, 16S rRNA maturation enzyme	153
648913962	277	57.91	1	276	9	285	5.0e-101	360	COG4535	Mg2+ and Co2+ transporter CorC, contains CBS pair and CorC-HlyC domains	293
648913963	134	29.37	10	133	32	146	3.0e-08	51.1	COG2010	Cytochrome c, mono- and diheme variants	150
648913965	268	30.53	6	135	5	131	3.0e-07	49.3	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
648913966	128	40.94	1	127	1	127	5.0e-35	139	COG0736	Phosphopantetheinyl transferase (holo-ACP synthase)	127
648913967	242	65.7	1	239	1	242	8.0e-92	329	COG0854	Pyridoxine 5'-phosphate synthase PdxJ	243
648913968	291	38.55	7	280	4	274	1.0e-39	157	COG1108	ABC-type Mn2+/Zn2+ transport system, permease component	274
648913969	251	43.75	10	243	2	241	3.0e-71	261	COG1121	ABC-type Mn2+/Zn2+ transport system, ATPase component	254
648913970	223	44.1	1	219	1	226	2.0e-55	208	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
648913971	418	24.06	81	398	1	316	6.0e-34	138	COG0642	Signal transduction histidine kinase	336
648913973	722	45.71	1	722	1	730	0.0e+00	810	COG1198	Primosomal protein N' (replication factor Y) - superfamily II helicase	730
648913974	266	20.68	35	266	10	243	2.0e-24	106	COG1651	Protein-disulfide isomerase	244
648913975	224	42.33	1	213	1	215	2.0e-49	189	COG0819	Thiaminase	218
648913976	353	53.26	1	351	1	337	6.0e-125	440	COG0533	tRNA A37 threonylcarbamoyltransferase TsaD	342
648913978	396	29.86	121	395	1	281	4.0e-29	122	COG0755	ABC-type transport system involved in cytochrome c biogenesis, permease component	281
648913979	675	27.72	22	642	1	478	4.0e-96	346	COG1333	Cytochrome c biogenesis protein ResB	478
648913980	207	39.2	1	125	1	121	2.0e-26	112	COG2863	Cytochrome c553	121
648913981	215	48	1	199	1	199	4.0e-62	230	COG0218	GTP-binding protein EngB required for normal cell division	200
648913982	799	52.3	2	720	1	734	0.0e+00	932	COG5009	Membrane carboxypeptidase/penicillin-binding protein	797
648913983	368	40.52	24	368	10	353	1.0e-84	306	COG4972	Tfp pilus assembly protein, ATPase PilM	354
648913984	196	30.43	6	166	6	165	2.0e-25	108	COG3166	Tfp pilus assembly protein PilN	206
648913985	223	41.04	8	214	5	210	3.0e-45	175	COG3167	Tfp pilus assembly protein PilO	211
648913986	187	41.57	1	163	1	166	4.0e-36	144	COG3168	Tfp pilus assembly protein PilP	170
648913987	715	32	45	707	44	708	6.0e-104	372	COG4796	Type II secretory pathway, component HofQ	709
648913988	174	48.17	10	172	4	167	3.0e-53	200	COG0703	Shikimate kinase	172
648913989	359	56.39	1	359	1	358	0.0e+00	472	COG0337	3-dehydroquinate synthetase	360
648913990	280	49.41	1	253	1	247	3.0e-77	281	COG0121	Predicted glutamine amidotransferase	252
648913991	154	56.29	1	151	1	151	1.0e-52	199	COG1327	Transcriptional regulator NrdR, contains Zn-ribbon and ATP-cone domains	156
648913993	367	69.18	1	146	1	146	5.0e-60	225	COG0117	Pyrimidine deaminase domain of riboflavin biosynthesis protein RibD	146
648913994	434	47.99	6	422	2	421	0.0e+00	524	COG0677	UDP-N-acetyl-D-mannosaminuronate dehydrogenase	436
648913995	350	29.51	8	348	2	342	4.0e-50	192	COG0673	Predicted dehydrogenase	342
648913998	361	42.93	1	361	1	373	7.0e-108	384	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
648913999	474	22.11	3	471	9	480	2.0e-15	77.5	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
648914000	392	29.02	57	388	34	380	6.0e-38	151	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
648914002	358	23.48	1	354	3	375	3.0e-27	115	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
648914003	355	23.68	1	354	3	375	5.0e-26	112	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
648914004	390	19.08	99	390	80	380	2.0e-13	70.4	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
648914005	206	50.26	1	184	36	224	2.0e-65	242	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
648914007	224	20.17	5	223	1	226	2.0e-12	66.5	COG1011	FMN phosphatase YigB, HAD superfamily	229
648914008	261	28.19	3	245	2	253	3.0e-28	119	COG0223	Methionyl-tRNA formyltransferase	307
648914009	391	42.15	8	389	9	374	6.0e-116	411	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
648914010	633	43.7	17	625	1	588	0.0e+00	643	COG1086	NDP-sugar epimerase, includes UDP-GlcNAc-inverting 4,6-dehydratase FlaA1 and capsular polysaccharide biosynthesis protein EpsC	588
648914011	377	40	48	292	6	239	7.0e-42	164	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
648914012	153	34.72	8	150	1	139	3.0e-30	124	COG0394	Protein-tyrosine-phosphatase	139
648914013	726	23.21	6	454	1	458	2.0e-47	184	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
648914014	460	28.12	16	455	1	444	4.0e-50	192	COG1538	Outer membrane protein TolC	457
648914018	645	53.1	3	226	1	226	4.0e-80	292	COG1136	ABC-type lipoprotein export system, ATPase component	226
648914019	394	26.79	1	370	2	352	2.0e-29	123	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
648914021	140	33.33	1	129	1	139	4.0e-23	100	COG4968	Tfp pilus assembly protein PilE	139
648914022	242	61.34	1	237	1	237	2.0e-96	345	COG0217	Transcriptional and/or translational regulatory protein YebC/TACO1	241
648914023	475	52.81	2	459	1	450	0.0e+00	475	COG1115	Na+/alanine symporter	452
648914024	615	29.93	310	606	1	296	2.0e-25	111	COG0741	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)	296
648914026	867	39.93	1	861	7	859	0.0e+00	668	COG0308	Aminopeptidase N	859
648914028	447	78.3	1	447	1	447	0.0e+00	752	COG1726	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrA	447
648914029	410	73.09	2	405	1	400	0.0e+00	529	COG1805	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrB	400
648914030	258	66.79	1	258	1	262	1.0e-105	375	COG2869	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrC	264
648914031	208	80.77	1	208	1	208	8.0e-94	336	COG1347	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrD	208
648914032	197	83.84	1	197	1	198	6.0e-80	290	COG2209	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrE	198
648914033	405	88.45	1	405	4	410	0.0e+00	781	COG2871	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrF	410
648914036	387	39.26	15	387	1	363	3.0e-80	292	COG0687	Spermidine/putrescine-binding periplasmic protein	363
648914037	182	19.28	11	170	5	161	3.0e-08	51.9	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
648914038	661	46.56	2	661	1	635	0.0e+00	773	COG0187	DNA gyrase/topoisomerase IV, subunit B	635
648914039	155	35.67	5	155	24	179	3.0e-24	104	COG3038	Cytochrome b561	181
648914040	132	48.62	13	121	7	115	1.0e-26	111	COG2967	Uncharacterized protein affecting Mg2+/Co2+ transport	126
648914041	162	43.12	1	159	2	160	4.0e-31	127	COG1267	Phosphatidylglycerophosphatase A	160
648914042	319	47.5	1	318	3	317	5.0e-87	314	COG0611	Thiamine monophosphate kinase	317
648914044	316	26.73	1	301	1	295	2.0e-34	139	COG0583	DNA-binding transcriptional regulator, LysR family	297
648914045	244	37.93	27	228	9	211	3.0e-35	142	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
648914046	468	41.11	27	458	7	416	2.0e-125	442	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
648914047	83	37.66	4	80	1	73	6.0e-13	65.8	COG3313	Predicted Fe-S protein YdhL, DUF1289 family	74
648914048	1070	39.67	1	1063	1	1078	0.0e+00	885	COG1330	Exonuclease V gamma subunit	1078
648914049	468	40.79	15	466	4	442	4.0e-100	358	COG3182	Uncharacterized iron-regulated membrane protein	442
648914051	209	36.54	55	209	11	166	5.0e-36	144	COG1247	L-amino acid N-acyltransferase YncA	169
648914053	562	32.83	18	476	1	396	2.0e-77	283	COG0644	Dehydrogenase (flavoprotein)	396
648914056	302	35.55	6	302	17	303	6.0e-67	247	COG0803	ABC-type Zn uptake system ZnuABC, Zn-binding component ZnuA	303
648914057	250	35.66	4	240	3	246	6.0e-38	151	COG1381	Recombinational DNA repair protein (RecF pathway)	251
648914058	343	61.38	1	342	1	346	0.0e+00	499	COG0809	S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase)	348
648914062	456	64.67	1	448	1	449	0.0e+00	624	COG0439	Biotin carboxylase	449
648914063	295	41.12	1	295	2	300	2.0e-84	306	COG2264	Ribosomal protein L11 methylase PrmA	300
648914065	591	25.25	1	576	7	550	5.0e-67	249	COG4166	ABC-type oligopeptide transport system, periplasmic component	562
648914066	408	26.78	1	284	2	296	2.0e-37	150	COG1295	Uncharacterized membrane protein, BrkB/YihY/UPF0761 family (not an RNase)	303
648914067	201	33.33	5	199	3	205	3.0e-29	121	COG0655	Multimeric flavodoxin WrbA	207
648914068	94	40.7	1	85	10	95	9.0e-06	42.1	COG0640	DNA-binding transcriptional regulator, ArsR family	110
648914069	256	45.21	1	256	1	261	1.0e-90	326	COG0708	Exonuclease III	261
648914071	367	51.21	1	367	2	370	1.0e-111	396	COG2377	1,6-Anhydro-N-acetylmuramate kinase	371
648914072	379	42.71	2	374	1	377	1.0e-109	390	COG0116	23S rRNA G2445 N2-methylase RlmL	381
648914073	242	41.55	38	242	1	206	3.0e-58	218	COG0009	tRNA A37 threonylcarbamoyladenosine synthetase subunit TsaC/SUA5/YrdC	211
648914074	403	56.82	5	397	2	394	0.0e+00	557	COG0282	Acetate kinase	396
648914075	389	67.01	1	389	1	378	0.0e+00	536	COG2828	2-Methylaconitate cis-trans-isomerase PrpF (2-methyl citrate pathway)	378
648914076	869	50.92	4	865	2	861	0.0e+00	1108	COG1048	Aconitase A	861
648914077	384	47.83	1	384	3	390	1.0e-122	433	COG0372	Citrate synthase	390
648914078	291	62.07	1	290	1	289	1.0e-102	366	COG2513	2-Methylisocitrate lyase and related enzymes, PEP mutase family	289
648914079	439	58.43	9	438	4	436	4.0e-120	424	COG2252	Xanthine/uracil/vitamin C permease, AzgA family	436
648914080	310	26.73	11	303	9	304	2.0e-15	76.9	COG0679	Predicted permease	311
648914081	411	57.18	3	411	2	404	8.0e-113	400	COG0786	Na+/glutamate symporter	404
648914082	767	26.81	2	767	13	782	3.0e-62	233	COG4258	Predicted exporter	788
648914083	413	21.81	5	404	3	387	2.0e-34	140	COG0644	Dehydrogenase (flavoprotein)	396
648914084	194	34.92	1	173	1	188	2.0e-37	148	COG2249	Putative NADPH-quinone reductase (modulator of drug activity B)	189
648914086	405	33.25	1	400	1	409	3.0e-68	252	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
648914087	445	49.89	1	443	2	434	1.0e-114	406	COG0733	Na+-dependent transporter, SNF family	439
648914091	614	21.81	28	259	3	220	1.0e-12	68.9	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
648914092	405	29.95	6	373	10	402	8.0e-50	191	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
648914094	670	20.09	49	670	78	768	1.0e-31	132	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
648914095	518	47.35	1	242	6	249	8.0e-70	258	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
648914096	219	42.11	4	211	2	208	1.0e-50	192	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
648914097	632	28.16	2	632	1	574	1.0e-108	387	COG3850	Signal transduction histidine kinase, nitrate/nitrite-specific	574
648914098	457	39.2	10	451	1	404	2.0e-87	316	COG2223	Nitrate/nitrite transporter NarK	417
648914099	419	35.94	12	413	5	402	2.0e-86	312	COG2223	Nitrate/nitrite transporter NarK	417
648914100	227	47.11	4	227	2	224	1.0e-55	209	COG2181	Nitrate reductase gamma subunit	228
648914101	216	39.41	5	174	4	170	4.0e-34	138	COG2180	Nitrate reductase assembly protein NarJ, required for insertion of molybdenum cofactor	179
648914102	522	70.67	1	506	1	505	0.0e+00	887	COG1140	Nitrate reductase beta subunit	513
648914103	119	23.21	1	112	1	111	8.0e-09	52.7	COG0662	Mannose-6-phosphate isomerase, cupin superfamily	127
648914104	1226	66.37	1	1220	1	1227	0.0e+00	1961	COG5013	Nitrate reductase alpha subunit	1227
648914105	300	50.17	6	298	6	299	4.0e-92	331	COG4973	Site-specific recombinase XerC	299
648914106	142	30.37	9	141	1	133	6.0e-17	80.3	COG0824	Acyl-CoA thioesterase FadM	137
648914107	354	47.27	1	329	1	286	2.0e-98	352	COG0191	Fructose/tagatose bisphosphate aldolase	286
648914111	64	50.88	4	60	2	58	2.0e-14	70.9	COG3024	Endogenous inhibitor of DNA gyrase, YacG/DUF329 family	65
648914112	202	36.22	1	196	1	194	2.0e-35	142	COG0237	Dephospho-CoA kinase	201
648914113	286	43.54	17	282	9	254	4.0e-36	145	COG1989	Prepilin signal peptidase PulO (type II secretory pathway) or related peptidase	254
648914114	413	41.46	18	413	2	397	3.0e-110	391	COG1459	Type II secretory pathway, component PulF	397
648914115	559	47.83	61	559	5	500	0.0e+00	568	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
648914118	544	49.82	1	532	1	522	0.0e+00	514	COG0459	Chaperonin GroEL (HSP60 family)	524
648914119	110	62.11	16	110	1	95	5.0e-34	136	COG0234	Co-chaperonin GroES (HSP10)	96
648914120	264	27.72	3	263	2	263	2.0e-37	149	COG0561	Hydroxymethylpyrimidine pyrophosphatase and other HAD family phosphatases	264
648914121	336	46.56	18	334	6	320	1.0e-101	363	COG0276	Protoheme ferro-lyase (ferrochelatase)	320
648914124	311	46.28	1	308	1	305	8.0e-82	297	COG0341	Preprotein translocase subunit SecF	305
648914125	620	50.77	76	596	2	501	0.0e+00	488	COG0342	Preprotein translocase subunit SecD	506
648914126	88	45.45	1	88	3	90	3.0e-21	93.3	COG1862	Preprotein translocase subunit YajC	97
648914127	369	39.57	21	342	3	325	5.0e-81	294	COG0123	Acetoin utilization deacetylase AcuC or a related deacetylase	340
648914128	354	34.53	1	352	2	350	4.0e-67	248	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
648914129	379	35.65	5	338	3	341	1.0e-75	277	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
648914133	531	69.32	1	527	1	528	0.0e+00	889	COG4108	Peptide chain release factor RF-3	528
648914134	259	30.38	4	259	1	256	2.0e-14	73.1	COG0730	Uncharacterized membrane protein YfcA	258
648914136	172	35.16	1	171	2	183	7.0e-32	130	COG3009	Uncharacterized lipoprotein YmbA	190
648914137	553	43.35	7	553	7	552	0.0e+00	591	COG3008	Paraquat-inducible protein B	553
648914138	437	39.51	20	422	11	409	6.0e-109	388	COG2995	Uncharacterized paraquat-inducible protein A	418
648914139	366	20.89	1	366	19	354	6.0e-28	118	COG3203	Outer membrane protein (porin)	354
648914140	275	49.21	13	264	2	252	5.0e-84	304	COG0101	tRNA U38,U39,U40 pseudouridine synthase TruA	266
648914141	789	18.87	2	787	30	754	6.0e-32	133	COG3170	Tfp pilus assembly protein FimV	755
648914142	178	44.07	1	176	1	176	9.0e-41	159	COG2917	Intracellular septation protein A	180
648914143	96	52.69	3	95	2	92	8.0e-22	95.4	COG2350	Uncharacterized conserved protein YciI, contains a putative active-site phosphohistidine	92
648914144	89	37.08	1	88	2	88	4.0e-13	66.5	COG0271	Stress-induced morphogen (activity unknown)	90
648914146	153	59.73	1	149	1	145	2.0e-54	204	COG1490	D-Tyr-tRNAtyr deacylase	145
648914147	558	46.52	4	540	1	530	0.0e+00	575	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
648914148	351	24.13	9	351	1	238	9.0e-33	134	COG0176	Transaldolase	239
648914149	325	57.21	8	207	1	201	1.0e-65	243	COG0794	D-arabinose 5-phosphate isomerase GutQ	202
648914150	190	39.38	1	174	1	188	5.0e-45	173	COG2818	3-methyladenine DNA glycosylase Tag	188
648914151	227	41.08	17	199	3	183	4.0e-49	187	COG0132	Dethiobiotin synthetase	223
648914152	429	47.06	6	428	5	446	0.0e+00	519	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
648914153	133	63.57	6	133	1	129	2.0e-43	168	COG0509	Glycine cleavage system H protein (lipoate-binding)	131
648914154	366	45.55	1	364	2	376	6.0e-102	364	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
648914155	160	40.91	1	154	1	154	2.0e-38	152	COG1522	DNA-binding transcriptional regulator, Lrp family	154
648914156	120	50.42	2	120	1	119	3.0e-30	123	COG2832	Uncharacterized membrane protein YbaN, DUF454 family	119
648914157	482	24.04	39	478	4	424	3.0e-54	206	COG1055	Na+/H+ antiporter NhaD or related arsenite permease	424
648914158	271	25.26	3	266	9	293	1.0e-32	133	COG3315	O-Methyltransferase involved in polyketide biosynthesis	297
648914160	359	38.72	8	358	2	352	3.0e-76	279	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
648914161	305	59.79	110	303	4	195	1.0e-80	293	COG0131	Imidazoleglycerol phosphate dehydratase HisB	195
648914164	290	37.06	7	288	1	286	2.0e-69	255	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
648914165	215	50.47	1	212	2	202	1.0e-73	269	COG0118	Imidazoleglycerol phosphate synthase glutamine amidotransferase subunit HisH	204
648914166	247	53.31	1	242	2	239	4.0e-82	297	COG0106	Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase	241
648914168	255	70.87	3	255	2	255	8.0e-113	399	COG0107	Imidazole glycerol phosphate synthase subunit HisF	256
648914169	132	62.39	1	109	3	111	3.0e-44	170	COG0139	Phosphoribosyl-AMP cyclohydrolase	111
648914170	107	54.95	6	96	1	91	2.0e-24	103	COG0140	Phosphoribosyl-ATP pyrophosphohydrolase	92
648914171	107	49.06	2	104	1	103	6.0e-25	105	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
648914172	68	30.88	1	68	1	68	2.0e-10	57.7	COG1826	Sec-independent protein translocase protein TatA	94
648914173	217	36.67	1	90	1	90	5.0e-13	68.1	COG1826	Sec-independent protein translocase protein TatA	94
648914174	258	51.19	4	252	1	252	3.0e-61	228	COG0805	Sec-independent protein secretion pathway component TatC	255
648914175	126	51.59	1	124	1	125	8.0e-27	112	COG3308	Uncharacterized membrane protein	131
648914176	625	20.35	38	425	25	398	5.0e-16	79.8	COG3307	O-antigen ligase	424
648914177	225	43.67	3	225	2	228	9.0e-59	220	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
648914178	457	27.27	131	457	12	330	2.0e-38	154	COG0642	Signal transduction histidine kinase	336
648914179	801	23.27	9	404	6	445	2.0e-40	161	COG1042	Acyl-CoA synthetase (NDP forming)	598
648914180	82	57.32	1	82	1	81	2.0e-25	106	COG0228	Ribosomal protein S16	87
648914181	169	38.95	1	169	1	172	9.0e-44	169	COG0806	Ribosomal 30S subunit maturation factor RimM, required for 16S rRNA processing	174
648914182	248	58.75	1	239	1	239	3.0e-100	357	COG0336	tRNA G37 N-methylase TrmD	240
648914183	121	65.52	1	116	3	115	6.0e-39	152	COG0335	Ribosomal protein L19	115
648914184	404	19.08	1	404	11	411	6.0e-28	118	COG1914	Mn2+ and Fe2+ transporters of the NRAMP family	416
648914185	445	47.09	18	445	1	411	0.0e+00	512	COG0334	Glutamate dehydrogenase/leucine dehydrogenase	411
648914186	264	74.81	1	264	3	268	1.0e-124	438	COG0207	Thymidylate synthase	268
648914190	1161	33.76	1	1158	1	1163	0.0e+00	674	COG1196	Chromosome segregation ATPase	1163
648914191	504	43.92	24	504	11	488	0.0e+00	516	COG0397	Uncharacterized conserved protein YdiU, UPF0061 family	488
648914192	322	55.73	1	319	2	320	4.0e-101	361	COG4607	ABC-type enterochelin transport system, periplasmic component	320
648914193	74	61.76	10	74	3	70	9.0e-21	91.6	COG5515	Uncharacterized protein	70
648914194	322	59.69	4	322	2	321	1.0e-96	346	COG4606	ABC-type enterochelin transport system, permease component	321
648914195	324	51.11	10	324	1	315	6.0e-93	334	COG4605	ABC-type enterochelin transport system, permease component	316
648914196	207	26.47	38	205	15	162	1.0e-07	50	COG2191	Formylmethanofuran dehydrogenase subunit E	206
648914197	252	56.57	1	251	1	251	4.0e-108	384	COG4604	ABC-type enterochelin transport system, ATPase component	252
648914198	382	22.8	15	377	4	330	2.0e-54	206	COG0620	Methionine synthase II (cobalamin-independent)	330
648914199	241	34.88	40	241	2	212	2.0e-44	172	COG0602	Organic radical activating enzyme	212
648914200	123	52.85	1	123	1	121	1.0e-29	121	COG3759	Uncharacterized membrane protein	121
648914201	140	36.05	1	140	3	127	3.0e-25	107	COG0720	6-pyruvoyl-tetrahydropterin synthase	127
648914203	219	46.76	4	214	3	213	5.0e-73	267	COG0603	7-cyano-7-deazaguanine synthase (queuosine biosynthesis)	222
648914204	199	28.8	14	199	1	188	2.0e-14	72.4	COG0558	Phosphatidylglycerophosphate synthase	192
648914205	206	53.03	4	201	5	202	2.0e-67	248	COG3647	Uncharacterized membrane protein YjdF	205
648914206	580	32.99	1	278	7	294	1.0e-44	174	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
648914211	228	26.4	17	210	40	226	4.0e-14	71.9	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
648914212	329	47.85	25	327	5	302	2.0e-89	322	COG4589	Predicted CDP-diglyceride synthetase/phosphatidate cytidylyltransferase	303
648914213	453	50.81	328	450	3	126	1.0e-31	131	COG3245	Cytochrome c5	126
648914214	55	34.04	1	47	5	51	3.0e-07	46.7	COG4736	Cbb3-type cytochrome oxidase, subunit 3	60
648914215	203	58.74	2	203	1	223	9.0e-88	316	COG2993	Cbb3-type cytochrome oxidase, cytochrome c subunit	227
648914216	482	74.89	9	480	10	481	0.0e+00	700	COG3278	Cbb3-type cytochrome oxidase, subunit 1	482
648914217	585	45.02	2	580	1	544	0.0e+00	547	COG3975	Predicted metalloprotease, contains C-terminal PDZ domain	558
648914218	144	45.8	1	131	1	130	7.0e-35	139	COG3453	Predicted phosphohydrolase, protein tyrosine phosphatase (PTP) superfamily, DUF442 family	130
648914219	146	44.06	1	143	1	136	1.0e-30	125	COG0848	Biopolymer transport protein ExbD	137
648914220	219	35.51	6	219	1	214	2.0e-39	155	COG0811	Biopolymer transport protein ExbB/TolQ	216
648914223	150	45.11	1	131	1	133	3.0e-32	130	COG1959	DNA-binding transcriptional regulator, IscR family	150
648914225	385	42.23	6	384	12	396	4.0e-75	275	COG3213	Uncharacterized protein involved in response to NO	396
648914226	338	47.34	1	336	1	329	0.0e+00	481	COG1087	UDP-glucose 4-epimerase	329
648914230	1209	22.74	477	834	36	388	2.0e-23	105	COG1887	CDP-glycerol glycerophosphotransferase, TagB/SpsB family	388
648914231	392	35.04	41	289	1	239	2.0e-37	150	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
648914232	391	69.02	26	391	12	372	0.0e+00	476	COG3524	Capsule polysaccharide export protein KpsE/RkpR	372
648914233	265	32.45	1	265	1	262	2.0e-45	175	COG1682	ABC-type polysaccharide/polyol phosphate export permease	263
648914234	216	39.27	1	215	24	241	7.0e-70	257	COG1134	ABC-type polysaccharide/polyol phosphate transport system, ATPase component	249
648914235	151	27.89	1	146	1	138	7.0e-20	90.1	COG4968	Tfp pilus assembly protein PilE	139
648914236	700	36.6	14	694	1	681	0.0e+00	614	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
648914237	431	20.6	19	409	8	340	7.0e-17	82.3	COG1566	Multidrug resistance efflux pump	352
648914241	440	26.03	3	432	22	451	9.0e-39	154	COG1538	Outer membrane protein TolC	457
648914242	355	68.47	2	352	1	337	0.0e+00	596	COG1088	dTDP-D-glucose 4,6-dehydratase	340
648914243	299	59.93	1	287	1	284	3.0e-119	421	COG1209	dTDP-glucose pyrophosphorylase	286
648914244	179	61.71	1	175	1	173	3.0e-65	240	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase or related enzyme	173
648914246	674	69.73	3	673	17	670	0.0e+00	916	COG3563	Capsule polysaccharide export protein KpsC/LpsZ	671
648914247	454	56.01	18	408	15	399	2.0e-127	449	COG3562	Capsule polysaccharide modification protein KpsS	403
648914248	480	38.44	20	477	2	454	2.0e-114	405	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
648914250	583	38.56	89	322	3	236	2.0e-49	190	COG0340	Biotin-(acetyl-CoA carboxylase) ligase	238
648914255	283	59.5	4	282	1	279	7.0e-110	390	COG0190	5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase	283
648914256	1092	19.77	220	1041	230	1002	7.0e-41	163	COG3419	Tfp pilus assembly protein, tip-associated adhesin PilY1	1036
648914259	376	58.71	4	376	3	367	0.0e+00	567	COG0505	Carbamoylphosphate synthase small subunit	368
648914261	129	55.04	1	129	1	129	7.0e-48	182	COG2852	Very-short-patch-repair endonuclease	129
648914263	1071	70.2	13	408	1	393	0.0e+00	591	COG0458	Carbamoylphosphate synthase large subunit	400
648914264	1493	45.28	1	1439	1	1322	0.0e+00	1402	COG4889	Predicted helicase	1518
648914267	226	45.18	3	225	1	227	2.0e-54	205	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
648914269	344	25.15	1	338	2	296	1.0e-31	131	COG1073	Fermentation-respiration switch protein FrsA, has esterase activity, DUF1100 family	299
648914270	411	20.82	16	401	21	367	9.0e-12	65.1	COG1106	ATPase/GTPase, AAA15 family	371
648914272	301	27.61	4	294	3	293	2.0e-30	127	COG0583	DNA-binding transcriptional regulator, LysR family	297
648914273	360	31.05	28	329	19	319	3.0e-29	122	COG0642	Signal transduction histidine kinase	336
648914274	326	19	125	324	69	260	1.0e-07	50.8	COG3087	Cell division protein FtsN	264
648914276	274	46.69	1	268	1	270	4.0e-71	261	COG1968	Undecaprenyl pyrophosphate phosphatase UppP	270
648914278	64	47.17	3	55	11	60	4.0e-09	53.1	COG4391	Uncharacterized conserved protein, contains Zn-finger domain	62
648914279	309	44.37	9	298	1	284	9.0e-73	267	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
648914280	434	33.59	173	430	6	231	8.0e-55	208	COG0860	N-acetylmuramoyl-L-alanine amidase	231
648914281	156	48.97	9	152	3	147	4.0e-46	177	COG0802	tRNA A37 threonylcarbamoyladenosine biosynthesis protein TsaE	149
648914282	269	48.31	5	269	4	268	9.0e-81	293	COG0796	Glutamate racemase	269
648914283	643	61.78	1	606	4	579	0.0e+00	657	COG0443	Molecular chaperone DnaK (HSP70)	579
648914284	180	46.96	6	179	14	193	1.0e-32	132	COG0576	Molecular chaperone GrpE (heat shock protein)	193
648914285	272	56.02	81	270	3	193	1.0e-67	249	COG1045	Serine acetyltransferase	194
648914286	292	38.28	4	287	20	304	2.0e-58	219	COG1560	Lauroyl/myristoyl acyltransferase	308
648914287	389	67.35	1	389	2	388	0.0e+00	657	COG0192	S-adenosylmethionine synthetase	388
648914288	97	41.67	1	81	10	93	1.0e-15	75.1	COG2960	Uncharacterized conserved protein YqiC, BMFP domain	103
648914289	499	56.53	16	499	2	488	0.0e+00	599	COG0606	Predicted ATPase with chaperone activity	490
648914290	119	47.9	1	119	1	119	2.0e-26	111	COG2018	Predicted regulator of Ras-like GTPase activity, Roadblock/LC7/MglB family	119
648914292	178	43.33	1	178	8	185	2.0e-44	171	COG2229	Signal recognition particle receptor subunit beta, a GTPase	187
648914296	348	50.43	3	348	1	349	1.0e-127	449	COG0002	N-acetyl-gamma-glutamylphosphate reductase	349
648914298	231	30.36	10	231	1	213	3.0e-37	149	COG2932	Phage repressor protein C, contains Cro/C1-type HTH and peptisase s24 domains	214
648914300	503	50.1	1	501	4	511	0.0e+00	523	COG0661	Predicted unusual protein kinase regulating ubiquinone biosynthesis, AarF/ABC1/UbiB family	517
648914301	258	42.21	2	255	1	260	1.0e-79	289	COG0708	Exonuclease III	261
648914302	330	54.08	1	330	1	328	2.0e-111	396	COG1995	4-hydroxy-L-threonine phosphate dehydrogenase PdxA	332
648914303	328	29.58	20	300	2	280	2.0e-54	206	COG0616	Periplasmic serine protease, ClpP class	317
648914305	438	38.66	22	286	1	265	8.0e-62	231	COG0548	Acetylglutamate kinase	265
648914308	213	38.39	3	210	1	201	3.0e-49	188	COG0461	Orotate phosphoribosyltransferase	201
648914309	221	35.32	5	219	1	218	4.0e-40	157	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
648914310	332	40.92	16	316	6	289	2.0e-68	252	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
648914311	989	52.55	1	489	1	487	0.0e+00	531	COG1530	Ribonuclease G or E	487
648914312	269	41.26	4	269	2	266	2.0e-41	162	COG0428	Zinc transporter ZupT	266
648914313	91	53.41	1	88	1	88	4.0e-34	136	COG2924	Fe-S cluster biosynthesis and repair protein YggX	90
648914315	300	35.25	3	296	8	293	4.0e-44	171	COG1575	1,4-dihydroxy-2-naphthoate octaprenyltransferase	303
648914316	228	31.6	1	228	5	233	1.0e-22	99	COG0670	Integral membrane protein, interacts with FtsH	233
648914317	171	43.67	7	164	3	156	3.0e-48	184	COG0669	Phosphopantetheine adenylyltransferase	159
648914320	556	21.66	10	379	11	370	2.0e-11	65	COG1479	Uncharacterized conserved protein, contains ParB-like and HNH nuclease domains	409
648914323	309	64.23	35	280	25	270	3.0e-103	368	COG2326	Polyphosphate kinase 2, PPK2 family	270
648914324	631	34.29	52	425	131	462	6.0e-84	305	COG0147	Anthranilate/para-aminobenzoate synthases component I	462
648914325	415	60.72	2	413	1	411	0.0e+00	487	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
648914326	78	62.34	1	77	3	79	4.0e-14	69.6	COG0236	Acyl carrier protein	80
648914328	673	47.39	3	671	1	648	0.0e+00	760	COG1505	Prolyl oligopeptidase PreP, S9A serine peptidase family	648
648914330	260	53.31	5	260	1	253	1.0e-82	299	COG0134	Indole-3-glycerol phosphate synthase	254
648914335	513	51.07	1	511	7	518	2.0e-118	419	COG0728	Peptidoglycan biosynthesis protein MviN/MurJ, putative lipid II flippase	518
648914336	317	40.68	5	317	2	321	5.0e-82	297	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
648914339	584	33.33	12	565	8	537	4.0e-58	219	COG2268	Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain	548
648914343	160	23.38	4	155	5	143	2.0e-19	88.5	COG1764	Organic hydroperoxide reductase OsmC/OhrA	143
648914348	220	24.19	8	218	6	218	1.0e-08	53.4	COG1842	Phage shock protein A	225
648914350	634	63.9	9	633	1	621	0.0e+00	982	COG0445	tRNA U34 5-carboxymethylaminomethyl modifying enzyme MnmG/GidA	621
648914352	254	38.68	1	240	1	233	4.0e-57	215	COG3967	Short-chain dehydrogenase involved in D-alanine esterification of teichoic acids	245
648914356	207	46.23	4	207	2	213	6.0e-57	214	COG0357	16S rRNA G527 N7-methylase RsmG (former glucose-inhibited division protein B)	215
648914357	258	42.02	3	257	2	257	9.0e-58	216	COG1192	Cellulose biosynthesis protein BcsQ	259
648914358	196	55.96	5	194	1	193	1.0e-61	229	COG0164	Ribonuclease HII	199
648914359	382	51.46	7	380	4	379	3.0e-124	438	COG0763	Lipid A disaccharide synthetase	381
648914360	258	55.43	1	258	3	260	2.0e-107	381	COG1043	Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase	260
648914361	154	52.74	4	147	1	142	2.0e-43	168	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
648914362	350	51.03	4	340	2	338	2.0e-96	346	COG1044	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase	338
648914363	168	38.79	10	168	6	170	7.0e-18	83.5	COG2825	Periplasmic chaperone for outer membrane proteins, Skp family	170
648914364	799	41.82	1	799	1	766	0.0e+00	712	COG4775	Outer membrane protein assembly factor BamA	766
648914366	394	59.17	4	389	2	379	0.0e+00	545	COG0743	1-deoxy-D-xylulose 5-phosphate reductoisomerase	385
648914367	251	29.36	17	248	13	233	3.0e-21	95.8	COG2859	Uncharacterized protein	237
648914368	264	33.83	1	264	1	264	3.0e-38	152	COG0575	CDP-diglyceride synthetase	265
648914369	248	53.48	14	237	16	245	2.0e-87	315	COG0020	Undecaprenyl pyrophosphate synthase	245
648914370	185	56.22	1	185	3	187	3.0e-61	227	COG0233	Ribosome recycling factor	187
648914371	796	62.48	5	566	2	563	0.0e+00	884	COG0187	DNA gyrase/topoisomerase IV, subunit B	635
648914374	723	31.74	5	723	15	719	6.0e-122	432	COG4773	Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid	719
648914375	136	42.76	1	136	4	155	5.0e-43	166	COG2969	Stringent starvation protein B	155
648914376	201	34.65	2	191	1	201	3.0e-31	128	COG0625	Glutathione S-transferase	211
648914377	267	38.46	11	267	7	250	2.0e-62	232	COG2857	Cytochrome c1	250
648914378	449	51.13	7	404	2	372	7.0e-92	331	COG1290	Cytochrome b subunit of the bc complex	381
648914379	193	34.2	1	192	2	167	2.0e-32	132	COG0723	Rieske Fe-S protein	177
648914380	249	41.94	5	249	4	250	1.0e-62	232	COG0327	Putative GTP cyclohydrolase 1 type 2, NIF3 family	250
648914381	310	32.67	5	301	1	296	3.0e-35	142	COG0583	DNA-binding transcriptional regulator, LysR family	297
648914382	484	45.72	42	484	5	448	9.0e-123	433	COG2239	Mg/Co/Ni transporter MgtE (contains CBS domain)	451
648914383	227	67.84	1	227	2	228	5.0e-106	377	COG0588	Phosphoglycerate mutase (BPG-dependent)	230
648914384	102	51.22	21	102	17	98	1.0e-19	87.7	COG3691	Uncharacterized conserved protein YfcZ, UPF0381/DUF406 family	98
648914386	769	42.32	17	767	13	751	0.0e+00	717	COG0188	DNA gyrase/topoisomerase IV, subunit A	804
648914387	525	20.83	224	525	31	333	4.0e-26	112	COG0642	Signal transduction histidine kinase	336
648914388	541	34.62	7	541	6	457	6.0e-101	361	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
648914389	246	46.02	11	236	1	217	1.0e-69	256	COG2360	Leu/Phe-tRNA-protein transferase	221
648914390	166	45.21	21	166	1	145	7.0e-39	153	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
648914391	133	40.31	1	121	3	131	4.0e-27	113	COG2913	Outer membrane protein assembly factor BamE, lipoprotein component of the BamABCDE complex	147
648914392	268	54.68	2	266	1	266	7.0e-91	327	COG0289	Dihydrodipicolinate reductase	266
648914394	363	66.67	1	363	1	372	0.0e+00	530	COG0012	Ribosome-binding ATPase YchF, GTP1/OBG family	372
648914396	432	49.31	1	431	2	400	0.0e+00	468	COG0162	Tyrosyl-tRNA synthetase	401
648914397	757	60.8	1	757	8	778	0.0e+00	975	COG2183	Transcriptional accessory protein Tex/SPT6	780
648914398	353	27.99	8	344	10	347	6.0e-42	164	COG3177	Fic family protein	348
648914400	164	38.81	31	164	7	140	3.0e-22	98	COG3193	Uncharacterized conserved protein GlcG, DUF336 family	141
648914401	945	52.41	1	945	1	877	0.0e+00	1176	COG0525	Valyl-tRNA synthetase	877
648914403	259	52.94	3	254	2	253	8.0e-93	333	COG0024	Methionine aminopeptidase	255
648914405	202	35.57	8	199	8	195	1.0e-33	136	COG2823	Osmotically-inducible protein OsmY, contains BON domain	196
648914406	197	59.78	4	182	1	176	1.0e-64	238	COG0279	Phosphoheptose isomerase	176
648914407	115	48.65	6	115	3	113	3.0e-35	140	COG0792	Predicted endonuclease distantly related to archaeal Holliday junction resolvase	114
648914408	295	48.39	12	289	1	275	1.0e-86	312	COG0313	16S rRNA C1402 (ribose-2'-O) methylase RsmI	275
648914409	122	40.17	1	115	1	114	2.0e-24	104	COG3189	Uncharacterized conserved protein YeaO, DUF488 family	117
648914411	152	33.33	10	96	5	93	4.0e-10	57.7	COG4969	Tfp pilus assembly protein, major pilin PilA	125
648914412	154	32.2	5	121	4	121	7.0e-13	66.9	COG4969	Tfp pilus assembly protein, major pilin PilA	125
648914413	239	59.66	3	239	1	238	3.0e-91	327	COG0528	Uridylate kinase	238
648914414	284	53.38	1	283	1	295	9.0e-83	300	COG0264	Translation elongation factor EF-Ts	296
648914415	242	56.72	1	238	1	237	6.0e-93	333	COG0052	Ribosomal protein S2	252
648914417	205	38.02	5	194	4	191	7.0e-36	143	COG0212	5-formyltetrahydrofolate cyclo-ligase	191
648914419	490	34.11	2	472	1	429	3.0e-105	376	COG0579	L-2-hydroxyglutarate oxidase LhgO	429
648914422	421	41.67	4	418	2	419	1.0e-117	416	COG1519	3-deoxy-D-manno-octulosonic-acid transferase	419
648914424	473	36.78	31	460	1	445	5.0e-90	325	COG0415	Deoxyribodipyrimidine photolyase	461
648914426	373	53.37	3	372	1	369	4.0e-122	431	COG0263	Glutamate 5-kinase	369
648914428	491	47.34	6	491	3	475	2.0e-96	346	COG1007	NADH:ubiquinone oxidoreductase subunit 2 (chain N)	475
648914429	498	53.01	2	497	1	490	0.0e+00	525	COG1008	NADH:ubiquinone oxidoreductase subunit 4 (chain M)	497
648914430	382	21.91	2	165	27	194	3.0e-06	46.5	COG3886	HKD family nuclease	198
648914431	106	18.1	1	104	10	110	1.0e-06	45.4	COG0662	Mannose-6-phosphate isomerase, cupin superfamily	127
648914432	108	35.87	1	92	1	92	1.0e-12	64.6	COG1605	Chorismate mutase	101
648914433	674	41.63	7	667	1	606	0.0e+00	486	COG1009	NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit	606
648914434	191	44.95	1	188	14	201	7.0e-50	190	COG2184	Fido, protein-threonine AMPylation domain	201
648914435	101	61.39	1	101	1	100	2.0e-23	100	COG0713	NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K)	100
648914436	223	49.11	1	169	1	165	1.0e-32	133	COG0839	NADH:ubiquinone oxidoreductase subunit 6 (chain J)	166
648914437	159	45.73	1	159	3	161	3.0e-42	164	COG1143	Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)	172
648914441	358	49.56	17	355	3	332	3.0e-96	345	COG1005	NADH:ubiquinone oxidoreductase subunit 1 (chain H)	332
648914442	753	41.24	1	713	1	693	0.0e+00	696	COG1034	NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)	693
648914443	118	56.88	7	115	12	120	7.0e-37	145	COG2852	Very-short-patch-repair endonuclease	129
648914444	431	60.61	1	423	3	424	0.0e+00	653	COG1894	NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F)	424
648914445	174	26.97	15	163	23	164	4.0e-10	58.2	COG4333	Uncharacterized protein	167
648914446	157	47.77	1	157	4	157	6.0e-51	193	COG1905	NADH:ubiquinone oxidoreductase 24 kD subunit (chain E)	160
648914447	418	59.81	1	418	8	398	0.0e+00	619	COG0649	NADH:ubiquinone oxidoreductase 49 kD subunit (chain D)	398
648914448	261	45	64	243	2	171	2.0e-48	185	COG0852	NADH:ubiquinone oxidoreductase 27 kD subunit (chain C)	176
648914449	197	67.5	37	196	10	169	8.0e-74	269	COG0377	NADH:ubiquinone oxidoreductase 20 kD subunit (chhain B) or related Fe-S oxidoreductase	194
648914450	118	58.47	1	118	4	121	4.0e-31	126	COG0838	NADH:ubiquinone oxidoreductase subunit 3 (chain A)	123
648914451	243	43.09	43	220	12	192	4.0e-43	168	COG1611	Predicted Rossmann fold nucleotide-binding protein	205
648914453	620	17.51	14	618	2	696	5.0e-61	229	COG0557	Exoribonuclease R	706
648914455	268	41.79	1	268	2	265	2.0e-55	209	COG4137	ABC-type uncharacterized transport system, permease component	265
648914456	456	61.62	1	455	1	451	0.0e+00	616	COG0541	Signal recognition particle GTPase	451
648914459	201	68	1	200	1	200	1.0e-83	302	COG3560	Fatty acid repression mutant protein (predicted oxidoreductase)	200
648914460	133	37.31	7	133	10	142	4.0e-10	57.3	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
648914461	298	29.9	3	298	2	296	4.0e-37	148	COG0583	DNA-binding transcriptional regulator, LysR family	297
648914462	1400	25.46	33	1381	3	1275	0.0e+00	540	COG2911	Autotransporter translocation and assembly factor TamB	1278
648914463	621	29.22	61	621	31	594	4.0e-106	379	COG0729	Outer membrane translocation and assembly module TamA	594
648914464	405	73.58	1	405	1	403	0.0e+00	541	COG3633	Na+/serine symporter	407
648914465	481	38.91	1	481	8	498	3.0e-107	382	COG3104	Dipeptide/tripeptide permease	498
648914466	595	28.16	160	552	2	383	9.0e-55	208	COG0006	Xaa-Pro aminopeptidase	384
648914468	234	39.47	5	231	1	217	3.0e-44	172	COG0850	Septum formation inhibitor MinC	219
648914469	270	68.15	1	270	1	269	3.0e-122	431	COG2894	Septum formation inhibitor-activating ATPase MinD	272
648914470	88	51.14	1	88	1	86	7.0e-23	98.7	COG0851	Septum formation topological specificity factor MinE	88
648914471	306	30.87	1	295	1	289	2.0e-34	139	COG0583	DNA-binding transcriptional regulator, LysR family	297
648914472	141	47.41	1	135	1	135	2.0e-31	128	COG0355	FoF1-type ATP synthase, epsilon subunit	135
648914473	465	75.58	1	465	1	466	0.0e+00	829	COG0055	FoF1-type ATP synthase, beta subunit	468
648914474	291	50.17	5	291	1	286	6.0e-95	340	COG0224	FoF1-type ATP synthase, gamma subunit	287
648914475	515	66.21	1	515	1	504	0.0e+00	808	COG0056	FoF1-type ATP synthase, alpha subunit	504
648914476	177	37.64	1	176	1	178	4.0e-36	144	COG0712	FoF1-type ATP synthase, delta subunit	178
648914477	156	41.18	4	156	6	158	3.0e-16	78	COG0711	FoF1-type ATP synthase, membrane subunit b or b'	161
648914479	288	36.71	3	288	4	246	2.0e-47	183	COG0356	FoF1-type ATP synthase, membrane subunit a	246
648914480	117	30.25	1	117	11	128	9.0e-10	55.6	COG3312	FoF1-type ATP synthase assembly protein I	128
648914481	286	40	27	274	3	238	3.0e-35	142	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
648914482	187	52.94	3	187	2	187	1.0e-67	249	COG0163	3-polyprenyl-4-hydroxybenzoate decarboxylase	191
648914485	503	59	8	503	3	501	0.0e+00	711	COG1190	Lysyl-tRNA synthetase (class II)	502
648914486	343	29.51	22	325	18	297	9.0e-55	207	COG0630	Type IV secretory pathway ATPase VirB11/Archaellum biosynthesis ATPase	312
648914487	403	26.2	52	403	21	358	8.0e-38	151	COG2948	Type IV secretory pathway, VirB10 components	360
648914488	250	24.88	31	247	41	236	3.0e-16	79.3	COG3504	Type IV secretory pathway, VirB9 components	265
648914489	281	29.25	1	245	1	238	1.0e-27	116	COG3736	Type IV secretory pathway, component VirB8	239
648914496	328	17.91	23	302	59	349	1.0e-08	54.2	COG3704	Type IV secretory pathway, VirB6 components	406
648914499	812	36.01	5	801	14	792	0.0e+00	546	COG3451	Type IV secretory pathway, VirB4 component	796
648914504	326	29.15	58	323	2	250	1.0e-42	167	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
648914505	149	62	2	149	3	148	1.0e-32	132	COG3399	Uncharacterized protein	148
648914507	298	37.24	5	298	1	322	2.0e-62	232	COG0142	Geranylgeranyl pyrophosphate synthase	322
648914508	74	40.85	1	71	5	75	6.0e-07	45.7	COG1722	Exonuclease VII small subunit	81
648914509	288	39.93	1	287	3	293	4.0e-77	281	COG1162	Putative ribosome biogenesis GTPase RsgA	301
648914510	205	42.01	1	202	1	218	2.0e-41	162	COG2979	Uncharacterized membrane protein YebE, DUF533 family	225
648914511	456	35.75	11	456	1	435	2.0e-113	403	COG0015	Adenylosuccinate lyase	438
648914512	199	23.98	2	191	17	202	9.0e-17	80.3	COG2949	Uncharacterized periplasmic protein SanA, affects membrane permeability for vancomycin	235
648914513	367	66.95	130	367	1	239	1.0e-99	356	COG1186	Protein chain release factor B	239
648914514	305	36.36	51	305	12	297	9.0e-49	187	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
648914515	618	35.92	40	607	13	567	1.0e-115	410	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
648914517	193	53.23	1	192	1	201	6.0e-59	220	COG0632	Holliday junction resolvasome RuvABC DNA-binding subunit	201
648914518	245	45.05	42	223	58	233	9.0e-45	173	COG0797	Rare lipoprotein A, peptidoglycan hydrolase digesting "naked" glycans, contains C-terminal SPOR domain	233
648914519	154	64.29	1	153	2	154	3.0e-64	237	COG0219	tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain	155
648914520	240	37.93	6	236	2	223	3.0e-42	165	COG1040	Predicted amidophosphoribosyltransferases	225
648914521	304	24.71	64	303	24	282	1.0e-16	80.9	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
648914523	871	43.8	463	868	1	377	6.0e-121	429	COG1454	Alcohol dehydrogenase, class IV	377
648914524	732	33.05	28	730	2	636	4.0e-122	432	COG1199	Rad3-related DNA helicase	654
648914525	153	37.21	28	153	3	129	2.0e-24	105	COG4922	Predicted SnoaL-like aldol condensation-catalyzing enzyme	129
648914526	218	41.28	1	216	1	210	3.0e-47	181	COG2910	Putative NADH-flavin reductase	211
648914527	296	26.94	3	295	2	296	3.0e-29	122	COG0583	DNA-binding transcriptional regulator, LysR family	297
648914528	94	44.44	5	85	4	84	2.0e-18	83.8	COG2827	Predicted endonuclease, GIY-YIG superfamily	95
648914529	173	47.24	44	170	12	126	6.0e-19	87.4	COG3245	Cytochrome c5	126
648914531	392	54	1	390	2	393	0.0e+00	483	COG0126	3-phosphoglycerate kinase	395
648914532	519	34.5	6	519	48	587	8.0e-98	351	COG0369	Sulfite reductase, alpha subunit (flavoprotein)	587
648914533	458	30.79	44	458	20	435	2.0e-71	263	COG0612	Predicted Zn-dependent peptidase	438
648914534	442	24.13	8	431	2	429	6.0e-57	215	COG0612	Predicted Zn-dependent peptidase	438
648914535	622	49.83	4	600	3	590	0.0e+00	712	COG0514	Superfamily II DNA helicase RecQ	590
648914538	423	61.27	1	423	1	425	0.0e+00	611	COG0151	Phosphoribosylamine-glycine ligase	428
648914539	204	34	3	200	1	200	5.0e-44	170	COG1739	Putative translation regulator, IMPACT (imprinted ancient) protein family	203
648914540	311	50.47	1	311	1	312	1.0e-84	306	COG2025	Electron transfer flavoprotein, alpha subunit	313
648914541	249	45	1	249	1	260	8.0e-65	240	COG2086	Electron transfer flavoprotein, alpha and beta subunits	260
648914542	326	31.27	1	300	12	309	8.0e-51	194	COG0859	ADP-heptose:LPS heptosyltransferase	334
648914543	211	27.27	5	186	9	179	4.0e-20	91.8	COG1335	Nicotinamidase-related amidase	205
648914544	226	49.68	1	157	3	153	8.0e-43	167	COG1720	tRNA (Thr-GGU) A37 N-methylase	156
648914545	334	58.46	3	333	2	333	1.0e-128	452	COG0057	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase	335
648914546	305	57.67	1	300	2	297	2.0e-122	432	COG0774	UDP-3-O-acyl-N-acetylglucosamine deacetylase	300
648914548	76	51.39	1	72	1	71	9.0e-21	91.6	COG3205	Uncharacterized membrane protein	72
648914549	482	63.79	1	474	2	473	0.0e+00	814	COG0362	6-phosphogluconate dehydrogenase	473
648914550	600	44.13	43	600	1	539	0.0e+00	571	COG0405	Gamma-glutamyltranspeptidase	539
648914553	303	45.08	5	299	1	292	5.0e-64	238	COG2962	Uncharacterized membrane protein RarD, contains two EamA domains	293
648914554	294	25.87	11	292	4	282	3.0e-30	125	COG1307	Fatty acid-binding protein DegV (function unknown)	282
648914555	162	44.51	3	159	1	164	7.0e-39	153	COG0262	Dihydrofolate reductase	167
648914558	464	40.17	2	462	9	466	0.0e+00	469	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
648914561	220	24.43	1	220	15	222	7.0e-20	91	COG1434	Uncharacterized SAM-binding protein YcdF, DUF218 family	223
648914562	120	40.71	7	119	5	116	9.0e-28	115	COG1393	Arsenate reductase and related proteins, glutaredoxin family	117
648914563	160	24.73	9	100	1	91	1.0e-06	46	COG0526	Thiol-disulfide isomerase or thioredoxin	127
648914564	252	52.31	37	252	1	216	2.0e-86	312	COG2884	ABC-type ATPase involved in cell division	223
648914565	305	35.79	6	304	2	297	6.0e-62	231	COG2177	Cell division protein FtsX	297
648914566	159	57.24	6	157	11	162	3.0e-49	187	COG1546	Nicotinamide mononucleotide (NMN) deamidase PncC	162
648914567	187	19.5	1	186	1	199	6.0e-08	50.8	COG3637	Opacity protein and related surface antigens	199
648914569	143	36.89	11	109	25	127	7.0e-15	73.2	COG3794	Plastocyanin	128
648914570	255	36.19	1	253	2	258	2.0e-56	212	COG1120	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	258
648914571	348	38.81	18	348	2	330	9.0e-47	180	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
648914573	371	28.36	6	341	15	319	3.0e-36	146	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
648914575	685	40.85	1	556	3	558	0.0e+00	629	COG0143	Methionyl-tRNA synthetase	558
648914577	143	44.22	1	143	5	149	6.0e-34	136	COG1981	Uncharacterized membrane protein	149
648914578	156	56.49	1	154	1	154	5.0e-57	213	COG2954	CYTH domain, found in class IV adenylate cyclase and various triphosphatases	156
648914579	417	65.71	1	417	1	420	0.0e+00	628	COG0766	UDP-N-acetylglucosamine enolpyruvyl transferase	421
648914580	444	37.17	73	443	35	373	7.0e-95	341	COG2821	Membrane-bound lytic murein transglycosylase	373
648914581	278	38.08	1	271	7	308	7.0e-50	190	COG0672	High-affinity Fe2+/Pb2+ permease	383
648914582	387	65.16	13	387	1	376	0.0e+00	471	COG2822	Iron uptake system EfeUOB, periplasmic (or lipoprotein) component EfeO/EfeM	376
648914583	423	42.3	43	422	7	351	9.0e-92	330	COG2837	Periplasmic deferrochelatase/peroxidase EfeB	352
648914585	552	29.22	14	549	29	569	7.0e-89	321	COG3505	Type IV secretory pathway, VirD4 component, TraG/TraD family ATPase	596
648914595	859	47.58	1	855	1	842	0.0e+00	927	COG0249	DNA mismatch repair ATPase MutS	843
648914596	334	37.97	1	334	4	336	1.0e-80	293	COG4143	ABC-type thiamine transport system, periplasmic component	336
648914597	215	31.07	1	194	2	206	3.0e-25	108	COG1011	FMN phosphatase YigB, HAD superfamily	229
648914599	458	57.02	5	453	2	457	0.0e+00	620	COG1207	Bifunctional protein GlmU, N-acetylglucosamine-1-phosphate-uridyltransferase/glucosamine-1-phosphate-acetyltransferase	460
648914603	281	44.89	14	186	27	197	4.0e-38	152	COG3179	Predicted chitinase	206
648914604	612	50.82	1	612	1	597	0.0e+00	777	COG0449	Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains	597
648914605	145	39.13	8	145	5	141	4.0e-32	130	COG3787	Uncharacterized conserved protein YhbP, UPF0306 family	145
648914606	476	52.43	7	456	2	452	0.0e+00	531	COG1115	Na+/alanine symporter	452
648914607	146	50	1	146	1	130	1.0e-33	135	COG1970	Large-conductance mechanosensitive channel	130
648914608	261	64.34	1	258	1	256	2.0e-106	378	COG0623	Enoyl-[acyl-carrier-protein] reductase (NADH)	259
648914610	685	54.03	3	682	7	685	0.0e+00	948	COG0855	Polyphosphate kinase	696
648914611	103	56.73	1	103	17	120	3.0e-19	86.6	COG1734	RNA polymerase-binding transcription factor DksA	120
648914616	138	54.17	20	138	1	120	2.0e-25	107	COG1734	RNA polymerase-binding transcription factor DksA	120
648914618	265	41.2	1	261	2	266	2.0e-63	235	COG0345	Pyrroline-5-carboxylate reductase	266
648914619	231	52.4	2	229	1	228	8.0e-79	286	COG0325	Uncharacterized pyridoxal phosphate-containing protein, affects Ilv metabolism, UPF0001 family	228
648914620	348	64.93	1	345	3	347	0.0e+00	527	COG2805	Tfp pilus assembly protein PilT, pilus retraction ATPase	353
648914621	409	56.2	31	409	1	374	0.0e+00	517	COG5008	Tfp pilus assembly protein, ATPase PilU	375
648914623	639	58.41	4	637	2	625	0.0e+00	892	COG1154	Deoxyxylulose-5-phosphate synthase	627
648914626	447	36.08	11	432	1	403	0.0e+00	472	COG0137	Argininosuccinate synthase	403
648914627	266	32.58	1	263	1	255	4.0e-63	235	COG1058	Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA	255
648914628	334	48.26	1	332	12	351	2.0e-104	372	COG3178	Predicted phosphotransferase, aminoglycoside/choline kinase (APH/ChoK) family	351
648914629	804	33.02	90	799	46	776	2.0e-127	450	COG1452	LPS assembly outer membrane protein LptD (organic solvent tolerance protein OstA)	784
648914630	304	23	3	294	2	295	3.0e-14	72.8	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
648914631	177	23.81	19	176	15	177	7.0e-08	50.3	COG3545	Predicted esterase of the alpha/beta hydrolase fold	181
648914632	156	49.03	1	155	1	155	4.0e-52	196	COG1576	23S rRNA pseudoU1915 N3-methylase RlmH	155
648914633	125	73.28	1	116	1	116	2.0e-44	171	COG0203	Ribosomal protein L17	116
648914634	328	51.25	8	326	1	317	1.0e-96	346	COG0202	DNA-directed RNA polymerase, alpha subunit/40 kD subunit	317
648914635	206	61.54	1	206	1	205	4.0e-61	227	COG0522	Ribosomal protein S4 or related protein	205
648914636	131	64.84	4	131	2	129	5.0e-46	176	COG0100	Ribosomal protein S11	129
648914637	120	66.12	1	120	1	121	3.0e-41	160	COG0099	Ribosomal protein S13	121
648914638	72	61.11	1	72	1	72	1.0e-24	104	COG0361	Translation initiation factor IF-1	75
648914639	438	50.35	12	428	14	432	5.0e-117	414	COG0201	Preprotein translocase subunit SecY	436
648914640	144	52	1	144	1	150	2.0e-31	128	COG0200	Ribosomal protein L15	152
648914641	61	50	7	60	1	54	2.0e-11	60.9	COG1841	Ribosomal protein L30/L7E	55
648914642	172	58.43	5	169	16	181	4.0e-55	207	COG0098	Ribosomal protein S5	181
648914643	117	49.17	1	117	6	125	1.0e-27	114	COG0256	Ribosomal protein L18	125
648914644	177	54.24	1	176	1	176	2.0e-58	218	COG0097	Ribosomal protein L6P/L9E	178
648914645	130	66.41	1	129	1	131	1.0e-45	175	COG0096	Ribosomal protein S8	132
648914646	101	59.02	41	101	1	61	6.0e-16	75.6	COG0199	Ribosomal protein S14	61
648914647	179	67.04	1	179	1	179	8.0e-76	276	COG0094	Ribosomal protein L5	180
648914648	107	55.14	1	106	2	104	2.0e-17	80.3	COG0198	Ribosomal protein L24	104
648914649	122	74.59	1	122	1	122	3.0e-49	186	COG0093	Ribosomal protein L14	122
648914650	87	61.18	1	85	2	86	2.0e-23	100	COG0186	Ribosomal protein S17	87
648914651	63	50	2	63	4	65	8.0e-09	52.2	COG0255	Ribosomal protein L29	69
648914652	138	63.5	1	135	2	138	7.0e-46	176	COG0197	Ribosomal protein L16/L10AE	146
648914653	231	55.56	12	229	1	225	7.0e-76	277	COG0092	Ribosomal protein S3	233
648914654	109	63.89	1	108	9	116	7.0e-34	135	COG0091	Ribosomal protein L22	120
648914655	92	67.39	1	92	1	92	6.0e-37	145	COG0185	Ribosomal protein S19	93
648914656	277	59.34	1	272	1	273	2.0e-106	379	COG0090	Ribosomal protein L2	275
648914657	106	55.32	8	100	1	94	3.0e-23	99.9	COG0089	Ribosomal protein L23	94
648914658	206	40.95	1	206	2	211	2.0e-56	212	COG0088	Ribosomal protein L4	214
648914659	214	58.88	2	214	1	214	6.0e-73	267	COG0087	Ribosomal protein L3	218
648914660	103	71.84	1	103	1	103	6.0e-38	148	COG0051	Ribosomal protein S10	104
648914661	394	85.28	1	394	1	394	0.0e+00	732	COG0050	Translation elongation factor EF-Tu, a GTPase	394
648914662	701	64.58	1	701	1	693	0.0e+00	987	COG0480	Translation elongation factor EF-G, a GTPase	697
648914663	156	62.84	2	149	1	148	3.0e-54	203	COG0049	Ribosomal protein S7	148
648914664	123	76.42	1	123	7	129	2.0e-49	187	COG0048	Ribosomal protein S12	129
648914665	1395	50.23	15	853	1	806	0.0e+00	894	COG0086	DNA-directed RNA polymerase, beta' subunit/160 kD subunit	808
648914668	123	72.58	1	123	1	124	4.0e-28	116	COG0222	Ribosomal protein L7/L12	124
648914669	166	43.45	1	166	1	168	9.0e-33	133	COG0244	Ribosomal protein L10	175
648914670	231	60.09	1	227	1	228	4.0e-80	290	COG0081	Ribosomal protein L1	228
648914671	144	71.83	2	143	1	141	5.0e-54	203	COG0080	Ribosomal protein L11	141
648914672	177	54.8	1	177	1	177	5.0e-55	207	COG0250	Transcription antitermination factor NusG	178
648914674	394	85.28	1	394	1	394	0.0e+00	732	COG0050	Translation elongation factor EF-Tu, a GTPase	394
648914679	189	41.08	12	184	1	185	2.0e-43	168	COG0742	16S rRNA G966 N2-methylase RsmD	187
648914680	768	52.61	3	569	1	555	0.0e+00	677	COG0550	DNA topoisomerase IA	570
648914681	151	35.46	1	135	1	141	9.0e-38	149	COG2922	Uncharacterized conserved protein Smg, DUF494 family	157
648914682	393	41.94	1	391	1	350	9.0e-98	350	COG0758	Predicted Rossmann fold nucleotide-binding protein DprA/Smf involved in DNA uptake	350
648914683	492	20.9	20	395	5	353	4.0e-11	62.9	COG2814	Predicted arabinose efflux permease, MFS family	394
648914684	424	33.19	1	418	2	463	6.0e-93	334	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
648914685	710	39.01	1	701	7	707	0.0e+00	646	COG5000	Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation	712
648914687	425	33.43	92	424	3	353	5.0e-75	275	COG0144	16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family	355
648914688	308	52.6	1	306	2	307	8.0e-106	376	COG0223	Methionyl-tRNA formyltransferase	307
648914690	167	50.6	1	164	1	168	2.0e-56	211	COG0242	Peptide deformylase	168
648914693	152	53.59	1	152	2	153	5.0e-53	200	COG1781	Aspartate carbamoyltransferase, regulatory subunit	153
648914694	306	54.29	1	305	1	314	2.0e-116	412	COG0540	Aspartate carbamoyltransferase, catalytic chain	316
648914696	479	31.03	4	478	2	440	5.0e-81	295	COG2067	Long-chain fatty acid transport protein	440
648914698	443	14.96	47	436	58	434	5.0e-07	49.4	COG2270	MFS-type transporter involved in bile tolerance, Atg22 family	438
648914699	345	35.43	2	345	1	333	6.0e-68	251	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
648914701	546	45.12	48	535	3	446	0.0e+00	462	COG0166	Glucose-6-phosphate isomerase	446
648914702	273	51.61	1	273	2	271	1.0e-84	306	COG2171	Tetrahydrodipicolinate N-succinyltransferase	271
648914703	489	49.48	10	488	2	477	0.0e+00	539	COG0469	Pyruvate kinase	477
