gene_oid	gene_length	percent_identity	query_start	query_end	subj_start	subj_end	evalue	bit_score	cog_id	cog_name	cog_length
649912068	478	42.8	14	474	1	407	1.0e-116	413	COG0593	Chromosomal replication initiation ATPase DnaA	408
649912070	450	27.45	4	345	9	375	4.0e-46	179	COG1680	CubicO group peptidase, beta-lactamase class C family	390
649912071	842	32.22	37	840	5	753	2.0e-123	437	COG1193	dsDNA-specific endonuclease/ATPase MutS2	753
649912072	331	43.89	1	316	1	315	1.0e-91	330	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
649912074	329	60.67	1	326	3	325	0.0e+00	487	COG0113	Delta-aminolevulinic acid dehydratase, porphobilinogen synthase	330
649912077	176	24.85	20	173	29	193	2.0e-05	42.6	COG4636	Endonuclease, Uma2 family (restriction endonuclease fold)	200
649912078	472	45.05	6	458	5	450	2.0e-124	440	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
649912079	134	48.91	39	130	13	103	5.0e-25	106	COG1733	DNA-binding transcriptional regulator, HxlR family	120
649912081	366	29.28	1	360	1	335	2.0e-36	146	COG0673	Predicted dehydrogenase	342
649912084	284	32.49	1	268	2	275	5.0e-24	104	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
649912085	131	37.17	12	124	1	113	2.0e-24	105	COG1733	DNA-binding transcriptional regulator, HxlR family	120
649912087	439	44.11	1	433	23	454	1.0e-114	407	COG1113	L-asparagine transporter and related permeases	462
649912092	319	22.41	65	291	22	252	1.0e-16	80.7	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
649912093	187	26.01	8	179	1	162	1.0e-17	83.1	COG0262	Dihydrofolate reductase	167
649912094	137	22.56	8	122	4	134	1.0e-02	32.6	COG4319	Ketosteroid isomerase homolog	137
649912095	314	37.17	9	309	3	279	3.0e-70	259	COG0656	Aldo/keto reductase, related to diketogulonate reductase	280
649912097	109	47.62	1	105	2	106	7.0e-21	92.1	COG2076	Multidrug transporter EmrE and related cation transporters	106
649912098	218	19.49	6	197	10	176	1.0e-16	80	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
649912100	359	65.34	1	352	1	351	0.0e+00	542	COG0722	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase	351
649912106	429	31.58	221	427	1	204	2.0e-35	144	COG2140	Oxalate decarboxylase/archaeal phosphoglucose isomerase, cupin superfamily	209
649912107	179	53.7	17	178	3	162	7.0e-63	233	COG0386	Glutathione peroxidase, house-cleaning role in reducing lipid peroxides	162
649912108	745	71.97	10	743	3	729	0.0e+00	1155	COG0376	Catalase (peroxidase I)	730
649912110	335	42.2	1	323	1	316	3.0e-88	318	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
649912112	196	24.21	11	196	3	192	2.0e-05	42.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
649912113	854	18.82	519	854	76	419	9.0e-17	82.9	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
649912114	918	16.24	91	506	1	418	2.0e-14	75.6	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
649912114	918	21.51	520	918	22	408	9.0e-11	63	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
649912115	331	28.05	2	322	1	287	2.0e-31	130	COG2159	Predicted metal-dependent hydrolase, TIM-barrel fold	293
649912116	171	33.33	41	171	7	130	8.0e-17	79.9	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
649912117	192	25.47	9	168	2	162	4.0e-06	44.6	COG1309	DNA-binding transcriptional regulator, AcrR family	201
649912118	326	26.48	19	267	2	239	9.0e-24	104	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
649912119	390	29.59	9	385	1	365	6.0e-95	341	COG1932	Phosphoserine aminotransferase	365
649912122	445	29.59	65	445	29	403	2.0e-47	183	COG1228	Imidazolonepropionase or related amidohydrolase	406
649912123	314	30.36	1	298	1	297	3.0e-28	119	COG0583	DNA-binding transcriptional regulator, LysR family	297
649912124	234	17.8	6	228	21	282	3.0e-08	52.4	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
649912125	120	29.9	21	115	11	107	2.0e-09	54.8	COG1695	DNA-binding transcriptional regulator, PadR family	138
649912126	381	17.58	143	371	19	282	4.0e-05	42.8	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
649912127	322	27.83	206	320	1	108	1.0e-11	64.6	COG0607	Rhodanese-related sulfurtransferase	110
649912129	309	24.73	54	287	2	282	2.0e-18	86.3	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
649912130	544	19.79	279	538	45	317	1.0e-04	42.2	COG2706	6-phosphogluconolactonase, cycloisomerase 2 family	346
649912134	140	21.21	21	135	8	137	9.0e-04	36.3	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
649912135	305	21.72	48	305	14	272	1.0e-18	87.6	COG1082	Sugar phosphate isomerase/epimerase	274
649912138	145	27.27	1	141	1	140	1.0e-13	69.4	COG1848	Predicted nucleic acid-binding protein, contains PIN domain	140
649912139	244	36.12	1	227	9	211	9.0e-53	200	COG0321	Lipoate-protein ligase B	221
649912140	661	41.84	235	656	1	398	3.0e-94	339	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
649912141	232	27.23	11	195	3	182	2.0e-14	72.7	COG1751	Uncharacterized protein	186
649912145	386	41.69	7	385	1	367	1.0e-103	369	COG0026	Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)	375
649912146	166	57.93	2	165	1	162	4.0e-52	196	COG0041	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase	162
649912147	359	36.09	1	337	1	313	5.0e-61	228	COG2826	Transposase and inactivated derivatives, IS30 family	318
649912159	393	21.28	16	393	11	380	2.0e-08	53.8	COG4695	Phage portal protein BeeE	398
649912167	340	27.4	1	332	2	334	7.0e-33	134	COG0673	Predicted dehydrogenase	342
649912169	112	39.56	23	111	1	91	1.0e-16	78	COG2929	Uncharacterized conserved protein, DUF497 family	93
649912171	316	40.37	3	316	2	314	1.0e-55	210	COG0451	Nucleoside-diphosphate-sugar epimerase	314
649912172	452	47.11	16	442	2	424	0.0e+00	478	COG0677	UDP-N-acetyl-D-mannosaminuronate dehydrogenase	436
649912173	259	31.95	3	255	1	251	1.0e-34	140	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
649912176	217	43.6	15	217	1	211	2.0e-49	188	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
649912178	1997	17.29	658	1197	37	615	2.0e-07	53.3	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
649912189	199	39.11	14	195	2	201	2.0e-25	109	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
649912191	89	32.73	24	78	6	60	1.0e-05	41.3	COG1476	DNA-binding transcriptional regulator, XRE-family HTH domain	68
649912195	394	27.24	81	372	5	295	4.0e-20	92.6	COG4974	Site-specific recombinase XerD	300
649912197	191	28.42	1	186	5	192	6.0e-14	70.8	COG0558	Phosphatidylglycerophosphate synthase	192
649912198	164	36	2	151	1	140	2.0e-28	118	COG1959	DNA-binding transcriptional regulator, IscR family	150
649912199	414	58.21	13	398	1	386	0.0e+00	549	COG1104	Cysteine sulfinate desulfinase/cysteine desulfurase or related enzyme	386
649912201	141	52.74	1	127	5	146	1.0e-36	145	COG0822	NifU homolog involved in Fe-S cluster formation	150
649912202	155	45.61	41	154	2	109	7.0e-28	116	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
649912203	884	16.51	495	884	1	419	1.0e-15	79.4	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
649912204	283	25.87	38	283	3	282	2.0e-17	83.6	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
649912206	202	29.65	1	169	1	151	1.0e-10	60	COG1076	DnaJ-domain-containing proteins 1	174
649912207	137	21.13	7	137	2	135	3.0e-20	90.7	COG2764	Uncharacterized conserved protein PhnB, glyoxalase superfamily	136
649912208	659	47.94	8	611	2	578	0.0e+00	517	COG0443	Molecular chaperone DnaK (HSP70)	579
649912210	219	65.54	41	217	5	175	1.0e-68	253	COG5405	ATP-dependent protease HslVU (ClpYQ), peptidase subunit	178
649912211	534	53.67	17	534	2	444	0.0e+00	592	COG1220	ATP-dependent protease HslVU (ClpYQ), ATPase subunit	444
649912212	181	29.19	19	171	16	176	1.0e-11	62.9	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
649912213	332	35.42	5	319	1	239	3.0e-59	222	COG0176	Transaldolase	239
649912216	184	38.76	4	181	2	178	9.0e-41	159	COG4502	5'(3')-deoxyribonucleotidase	180
649912219	143	38.3	7	141	4	143	2.0e-21	95	COG1764	Organic hydroperoxide reductase OsmC/OhrA	143
649912220	548	23.53	129	493	11	377	2.0e-28	121	COG2234	Zn-dependent amino- or carboxypeptidase, M28 family	435
649912221	356	37.46	14	340	2	339	6.0e-76	277	COG1194	Adenine-specific DNA glycosylase, acts on AG and A-oxoG pairs	342
649912223	938	30.57	489	917	3	436	6.0e-67	249	COG0612	Predicted Zn-dependent peptidase	438
649912226	258	30.7	19	245	4	207	1.0e-32	133	COG0177	Endonuclease III	211
649912227	567	53.66	244	562	16	342	2.0e-88	320	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
649912229	155	30.07	5	150	13	163	2.0e-11	61.9	COG5654	Uncharacterized conserved protein, contains RES domain	163
649912232	407	44.2	9	407	1	403	2.0e-116	413	COG2081	Predicted flavoprotein YhiN	408
649912236	180	50.84	2	179	1	169	4.0e-46	177	COG4675	Microcystin-dependent protein  (function unknown)	170
649912237	180	19.32	12	177	10	180	4.0e-05	41.5	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
649912240	253	40.08	4	243	60	294	1.0e-55	209	COG4302	Ethanolamine ammonia-lyase, small subunit	294
649912241	464	58.3	1	446	1	444	0.0e+00	670	COG4303	Ethanolamine ammonia-lyase, large subunit	453
649912242	446	27.72	1	443	4	447	3.0e-26	113	COG0531	Amino acid transporter	466
649912244	702	41.16	2	558	4	527	3.0e-126	446	COG3511	Phospholipase C	527
649912246	407	20	23	389	31	396	9.0e-10	58.3	COG2223	Nitrate/nitrite transporter NarK	417
649912247	852	22.39	115	831	31	765	1.0e-80	295	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
649912248	428	34.29	51	422	4	380	3.0e-71	262	COG0006	Xaa-Pro aminopeptidase	384
649912253	97	40.21	1	97	7	103	8.0e-11	58.7	COG0640	DNA-binding transcriptional regulator, ArsR family	110
649912254	1055	31.13	2	1043	1	1006	0.0e+00	673	COG0841	Multidrug efflux pump subunit AcrB	1009
649912255	417	27.62	28	417	6	368	5.0e-18	85.6	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
649912256	498	35.42	37	498	1	447	1.0e-63	237	COG1538	Outer membrane protein TolC	457
649912267	429	26.24	21	423	21	442	2.0e-26	114	COG1538	Outer membrane protein TolC	457
649912268	365	29.38	3	364	1	364	2.0e-30	126	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
649912269	1038	37.95	1	1024	2	1014	0.0e+00	882	COG3696	Cu/Ag efflux pump CusA	1027
649912270	1050	46.86	867	1039	8	181	1.0e-44	176	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
649912273	66	56.72	1	66	1	67	9.0e-20	88.3	COG1278	Cold shock protein, CspA family	67
649912279	850	18.66	86	710	47	641	2.0e-39	158	COG3408	Glycogen debranching enzyme (alpha-1,6-glucosidase)	641
649912280	300	56.06	17	280	1	264	4.0e-100	357	COG0413	Ketopantoate hydroxymethyltransferase	268
649912281	286	53.66	1	283	1	285	6.0e-93	334	COG0414	Panthothenate synthetase	285
649912282	414	50.13	1	390	5	387	6.0e-95	341	COG0452	Phosphopantothenoylcysteine synthetase/decarboxylase	392
649912283	140	52.46	2	123	1	122	6.0e-38	149	COG0853	Aspartate 1-decarboxylase	126
649912286	442	22.47	78	425	63	386	2.0e-06	47.5	COG2814	Predicted arabinose efflux permease, MFS family	394
649912287	355	33.51	4	347	3	357	8.0e-61	227	COG1858	Cytochrome c peroxidase	364
649912289	355	29.28	42	354	4	304	2.0e-26	113	COG3391	DNA-binding beta-propeller fold protein YncE	381
649912290	511	27.6	7	502	121	754	8.0e-57	215	COG4993	Glucose dehydrogenase	773
649912292	474	28.12	10	467	1	443	1.0e-50	194	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
649912293	319	30.25	1	310	3	274	5.0e-35	141	COG1082	Sugar phosphate isomerase/epimerase	274
649912294	390	27.37	1	377	1	335	6.0e-50	191	COG0673	Predicted dehydrogenase	342
649912297	193	32.16	23	193	15	179	8.0e-27	113	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
649912301	519	29.25	28	518	4	567	1.0e-67	250	COG3653	N-acyl-D-aspartate/D-glutamate deacylase	579
649912302	624	44.52	53	624	2	539	0.0e+00	541	COG0405	Gamma-glutamyltranspeptidase	539
649912303	269	21.2	75	269	1	216	2.0e-10	59.5	COG2755	Lysophospholipase L1 or related esterase	216
649912304	282	24.83	4	282	1	270	1.0e-17	83.7	COG1082	Sugar phosphate isomerase/epimerase	274
649912306	436	25.24	29	433	2	407	1.0e-30	127	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
649912307	455	49.45	8	455	2	435	0.0e+00	525	COG0017	Aspartyl/asparaginyl-tRNA synthetase	435
649912310	132	31.78	7	130	10	138	2.0e-07	48.1	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
649912311	70	34.29	1	69	15	84	1.0e-05	41.5	COG5450	Transcription regulator of the Arc/MetJ class	84
649912312	131	28.12	1	124	3	126	2.0e-10	57.9	COG1487	Predicted nucleic acid-binding protein, contains PIN domain	133
649912314	335	24.34	8	334	1	336	8.0e-37	148	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
649912318	365	56.72	1	365	1	372	0.0e+00	477	COG0012	Ribosome-binding ATPase YchF, GTP1/OBG family	372
649912319	211	27.4	4	209	3	208	1.0e-21	96.5	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
649912320	91	32.43	3	76	4	77	2.0e-07	47.6	COG5460	Uncharacterized conserved protein, DUF2164 family	82
649912323	375	41.53	3	354	1	315	1.0e-87	316	COG1181	D-alanine-D-alanine ligase and related ATP-grasp enzymes	317
649912326	280	38.08	17	270	7	251	5.0e-56	211	COG2134	CDP-diacylglycerol pyrophosphatase	252
649912328	694	50.72	1	694	5	666	0.0e+00	840	COG0272	NAD-dependent DNA ligase	667
649912329	355	28.48	1	153	1	151	5.0e-08	52.4	COG1988	Membrane-bound metal-dependent hydrolase YbcI, DUF457 family	190
649912332	208	21.79	1	153	11	160	2.0e-09	56	COG1238	Uncharacterized membrane protein YqaA, SNARE-associated domain	161
649912333	168	42.5	9	165	10	169	9.0e-34	136	COG0521	Molybdopterin biosynthesis enzyme MoaB	169
649912334	341	20.09	109	337	47	240	5.0e-04	39	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
649912336	306	41.83	2	306	1	305	3.0e-84	305	COG0324	tRNA A37 N6-isopentenylltransferase MiaA	308
649912339	441	40.27	10	441	3	423	6.0e-104	371	COG0044	Dihydroorotase or related cyclic amidohydrolase	430
649912340	326	43.67	17	323	9	313	1.0e-76	279	COG0540	Aspartate carbamoyltransferase, catalytic chain	316
649912342	202	53.67	24	199	1	177	2.0e-54	205	COG2065	Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase	179
649912344	456	20.24	42	449	47	455	2.0e-15	77.5	COG1538	Outer membrane protein TolC	457
649912346	242	26.17	100	206	1	106	4.0e-10	58.6	COG0789	DNA-binding transcriptional regulator, MerR family	124
649912348	293	39.19	19	288	1	266	3.0e-63	235	COG0294	Dihydropteroate synthase	274
649912349	487	24.74	84	455	29	409	6.0e-50	192	COG1322	DNA anti-recombination protein (rearrangement mutator) RmuC	448
649912350	424	45.98	240	409	1	172	9.0e-35	141	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
649912351	79	64.1	1	78	3	80	5.0e-12	62.6	COG0236	Acyl carrier protein	80
649912352	422	56.42	10	420	3	411	0.0e+00	483	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
649912353	448	34.62	4	441	9	443	6.0e-61	228	COG0534	Na+-driven multidrug efflux pump	455
649912358	150	32.03	8	146	10	161	1.0e-16	79.2	COG5654	Uncharacterized conserved protein, contains RES domain	163
649912366	309	27.32	103	294	60	243	4.0e-16	79.1	COG1651	Protein-disulfide isomerase	244
649912368	257	17.76	5	235	25	280	1.0e-05	43.9	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
649912372	332	27.9	10	316	34	316	1.0e-16	81	COG3391	DNA-binding beta-propeller fold protein YncE	381
649912376	412	32.49	29	412	6	371	1.0e-55	210	COG4299	Predicted acyltransferase	371
649912378	250	34.68	11	246	1	245	2.0e-39	156	COG1801	Uncharacterized conserved protein YecE, DUF72 family	263
649912379	346	31.96	8	339	18	337	8.0e-53	201	COG0429	Predicted hydrolase of the alpha/beta-hydrolase fold	345
649912385	436	23.92	19	410	4	380	7.0e-26	112	COG2814	Predicted arabinose efflux permease, MFS family	394
649912387	360	55.32	5	331	4	332	3.0e-112	398	COG0416	Fatty acid/phospholipid biosynthesis enzyme	338
649912388	61	57.89	1	57	1	57	7.0e-12	62.2	COG0333	Ribosomal protein L32	57
649912390	373	23.08	248	361	11	123	9.0e-04	38.3	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
649912391	184	28.4	30	183	2	157	1.0e-15	76.2	COG3708	Predicted transcriptional regulator YdeE, contains AraC-type DNA-binding domain	157
649912392	114	41.23	4	114	2	112	8.0e-26	108	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
649912393	434	20.5	144	415	27	291	2.0e-13	70.3	COG0501	Zn-dependent protease with chaperone function	302
649912394	578	22.72	41	527	1	437	2.0e-29	123	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
649912395	550	19.42	132	535	68	454	1.0e-16	82	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
649912396	219	28	41	185	21	161	1.0e-06	47	COG3184	Uncharacterized protein	183
649912399	156	26.62	9	146	2	140	5.0e-14	70.7	COG2193	Bacterioferritin (cytochrome b1)	157
649912401	617	32.67	15	602	15	601	1.0e-105	377	COG3387	Glucoamylase (glucan-1,4-alpha-glucosidase), GH15 family	612
649912403	119	35.79	5	97	15	109	3.0e-09	54	COG0640	DNA-binding transcriptional regulator, ArsR family	110
649912404	309	32.28	151	308	9	149	2.0e-16	80.5	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
649912406	191	33.83	2	134	1	131	8.0e-23	100	COG0231	Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)	131
649912407	871	32	73	403	56	394	6.0e-61	229	COG1472	Periplasmic beta-glucosidase and related glycosidases	397
649912409	130	44.19	1	129	8	136	2.0e-25	108	COG3193	Uncharacterized conserved protein GlcG, DUF336 family	141
649912410	678	32.26	9	486	116	628	7.0e-73	268	COG3525	N-acetyl-beta-hexosaminidase	732
649912412	604	49.76	1	602	5	584	0.0e+00	736	COG0173	Aspartyl-tRNA synthetase	585
649912417	437	48.65	4	436	3	424	5.0e-121	428	COG0124	Histidyl-tRNA synthetase	429
649912418	231	25.96	7	207	5	212	1.0e-19	90.3	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
649912419	189	24.87	1	189	5	197	6.0e-13	67.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
649912420	349	25.67	6	331	3	302	2.0e-29	123	COG0451	Nucleoside-diphosphate-sugar epimerase	314
649912421	1204	36.84	406	1174	249	1009	0.0e+00	700	COG0841	Multidrug efflux pump subunit AcrB	1009
649912423	1054	37.72	4	1026	3	1009	0.0e+00	938	COG0841	Multidrug efflux pump subunit AcrB	1009
649912424	548	30.32	118	489	27	366	8.0e-32	132	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
649912425	502	22.15	192	499	10	286	1.0e-21	98	COG0382	4-hydroxybenzoate polyprenyltransferase	289
649912426	369	45.03	14	367	4	335	5.0e-102	364	COG0016	Phenylalanyl-tRNA synthetase alpha subunit	335
649912427	688	36.7	43	687	14	650	0.0e+00	468	COG0072	Phenylalanyl-tRNA synthetase beta subunit	650
649912428	477	26.23	30	470	28	443	2.0e-27	117	COG0531	Amino acid transporter	466
649912429	490	40.14	23	459	29	458	4.0e-99	355	COG0165	Argininosuccinate lyase	459
649912431	434	32.7	117	425	4	306	7.0e-43	168	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
649912432	950	25.82	58	236	2	169	1.0e-11	65.9	COG2120	N-acetylglucosaminyl deacetylase, LmbE family	237
649912434	1021	61.27	17	1006	6	977	0.0e+00	1396	COG3383	Predicted molibdopterin-dependent oxidoreductase YjgC	978
649912435	146	29.93	15	145	10	145	2.0e-07	48.4	COG2427	Uncharacterized conserved protein YjgD, DUF1641 family	148
649912436	1218	19.18	30	623	193	779	3.0e-10	61.6	COG2374	Predicted extracellular nuclease	798
649912438	441	43.35	77	422	3	288	4.0e-74	272	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
649912439	251	18.52	1	249	11	279	2.0e-12	66.4	COG0682	Prolipoprotein diacylglyceryltransferase	287
649912441	352	25.38	196	322	1	127	1.0e-08	54.5	COG0526	Thiol-disulfide isomerase or thioredoxin	127
649912442	112	29.87	10	84	1	77	7.0e-09	52.6	COG3027	Cell division protein ZapA, inhibits GTPase activity of FtsZ	105
649912445	199	27.04	10	197	1	194	1.0e-21	96.5	COG4636	Endonuclease, Uma2 family (restriction endonuclease fold)	200
649912447	136	32.33	4	131	1	133	4.0e-16	77.2	COG1569	Predicted nucleic acid-binding protein, contains PIN domain	142
649912449	235	53.51	1	227	1	228	4.0e-73	267	COG0081	Ribosomal protein L1	228
649912450	243	38.86	1	175	1	175	6.0e-28	118	COG0244	Ribosomal protein L10	175
649912451	124	60.8	1	124	2	124	6.0e-21	93	COG0222	Ribosomal protein L7/L12	124
649912454	1396	49.31	19	853	7	807	0.0e+00	837	COG0086	DNA-directed RNA polymerase, beta' subunit/160 kD subunit	808
649912457	156	21.64	5	136	4	136	2.0e-08	51.8	COG1943	REP element-mobilizing transposase RayT	136
649912461	387	41.13	102	376	2	283	3.0e-81	295	COG2230	Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases	283
649912465	270	39.92	23	268	2	251	1.0e-41	163	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
649912468	380	32.33	3	377	11	440	7.0e-67	247	COG3325	Chitinase, GH18 family	441
649912469	388	38.32	50	380	57	437	6.0e-74	271	COG3325	Chitinase, GH18 family	441
649912470	387	27.09	28	376	13	366	3.0e-28	119	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
649912471	1079	44.98	21	1062	2	1007	0.0e+00	924	COG0841	Multidrug efflux pump subunit AcrB	1009
649912473	885	34.01	20	406	11	368	2.0e-61	231	COG1472	Periplasmic beta-glucosidase and related glycosidases	397
649912474	353	31.06	4	350	2	350	6.0e-60	224	COG3424	Predicted naringenin-chalcone synthase	356
649912476	367	24.8	1	360	2	360	7.0e-20	91.7	COG0644	Dehydrogenase (flavoprotein)	396
649912477	92	43.59	1	77	3	80	4.0e-07	46.5	COG0236	Acyl carrier protein	80
649912478	402	42.13	1	401	2	412	2.0e-92	332	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
649912480	709	52.37	1	706	9	694	0.0e+00	810	COG1523	Pullulanase/glycogen debranching enzyme	697
649912481	533	23.97	22	526	142	719	2.0e-59	223	COG4993	Glucose dehydrogenase	773
649912482	251	27.59	2	111	35	147	2.0e-07	50	COG2010	Cytochrome c, mono- and diheme variants	150
649912483	767	34.81	9	767	17	745	0.0e+00	474	COG3537	Putative alpha-1,2-mannosidase	768
649912485	400	49.6	1	360	1	370	0.0e+00	476	COG0562	UDP-galactopyranose mutase	374
649912486	436	19.1	44	366	64	416	2.0e-14	74.1	COG2723	Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase	460
649912488	701	23.74	380	691	28	322	8.0e-28	119	COG3469	Chitinase	332
649912491	822	43.63	85	819	4	701	0.0e+00	787	COG0317	(p)ppGpp synthase/hydrolase, HD superfamily	701
649912492	260	39.08	4	239	3	240	6.0e-65	240	COG1131	ABC-type multidrug transport system, ATPase component	293
649912494	710	38.92	45	705	2	648	0.0e+00	567	COG1505	Prolyl oligopeptidase PreP, S9A serine peptidase family	648
649912496	132	54.33	4	129	2	126	1.0e-34	138	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
649912497	135	58.59	8	134	2	129	6.0e-54	202	COG0229	Peptide methionine sulfoxide reductase MsrB	140
649912498	70	41.67	1	70	1	72	3.0e-15	73.4	COG0227	Ribosomal protein L28	77
649912499	198	23.12	4	198	1	199	7.0e-09	53.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
649912500	188	27.72	9	186	5	205	7.0e-24	103	COG1335	Nicotinamidase-related amidase	205
649912502	427	16.3	42	379	54	411	8.0e-06	45.2	COG2270	MFS-type transporter involved in bile tolerance, Atg22 family	438
649912503	375	25.26	52	339	35	290	8.0e-17	81.9	COG3547	Transposase	303
649912505	842	17.54	450	842	1	419	4.0e-14	74	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
649912506	154	42.98	36	147	15	128	6.0e-24	103	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
649912507	409	17.9	11	405	1	393	1.0e-18	88.3	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
649912515	263	34.24	75	257	1	177	8.0e-26	110	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
649912517	110	49.02	1	99	1	102	1.0e-20	91.8	COG0261	Ribosomal protein L21	103
649912518	85	60	1	85	1	85	6.0e-26	108	COG0211	Ribosomal protein L27	87
649912522	276	23.96	21	210	27	212	3.0e-08	52.8	COG0705	Membrane associated serine protease, rhomboid family	228
649912523	315	41.69	4	315	6	310	1.0e-71	263	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
649912528	252	29.84	13	247	5	246	7.0e-20	91.1	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
649912529	166	40.36	2	157	1	166	4.0e-45	173	COG0350	O6-methylguanine-DNA--protein-cysteine methyltransferase	168
649912532	237	26.29	16	178	2	175	2.0e-09	56.6	COG2203	GAF domain	175
649912534	517	28.27	44	514	1	448	1.0e-55	211	COG1231	Monoamine oxidase	450
649912535	162	37.88	29	160	13	128	1.0e-18	86.1	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
649912536	405	31.38	53	387	17	355	8.0e-62	231	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
649912538	521	23.26	40	427	58	447	8.0e-28	118	COG1032	Radical SAM superfamily enzyme YgiQ, UPF0313 family	490
649912539	654	33.95	17	651	13	650	0.0e+00	487	COG3733	Cu2+-containing amine oxidase	654
649912541	458	20.42	7	436	1	384	6.0e-14	72.5	COG2814	Predicted arabinose efflux permease, MFS family	394
649912542	311	34.81	1	310	4	310	1.0e-48	186	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
649912543	794	30.96	51	787	8	713	5.0e-115	409	COG4354	Uncharacterized protein, contains GBA2_N and DUF608 domains	721
649912544	358	73.7	1	345	2	345	0.0e+00	571	COG1089	GDP-D-mannose dehydratase	345
649912545	320	32.83	8	320	2	313	8.0e-44	170	COG0451	Nucleoside-diphosphate-sugar epimerase	314
649912547	396	34.82	23	388	10	376	9.0e-59	221	COG1820	N-acetylglucosamine-6-phosphate deacetylase	380
649912548	462	34.62	14	453	8	467	3.0e-88	319	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
649912552	817	44.79	13	812	8	749	0.0e+00	831	COG0058	Glucan phosphorylase	750
649912553	794	62.55	1	793	5	792	0.0e+00	1137	COG3957	Phosphoketolase	793
649912554	379	40.66	10	372	3	389	5.0e-101	361	COG0282	Acetate kinase	396
649912557	912	27.47	141	315	24	204	1.0e-23	105	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
649912558	338	24.8	19	259	4	251	1.0e-16	80.9	COG1216	Glycosyltransferase, GT2 family	305
649912559	249	39.09	13	249	7	226	4.0e-58	217	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
649912560	508	32.93	30	499	1	487	2.0e-103	370	COG5476	Microcystin degradation protein MlrC, contains DUF1485 domain	488
649912562	420	20	32	402	3	342	1.0e-30	127	COG0673	Predicted dehydrogenase	342
649912563	329	24.19	61	325	13	274	4.0e-20	92.6	COG1082	Sugar phosphate isomerase/epimerase	274
649912564	382	28.95	77	375	5	302	2.0e-38	153	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
649912565	430	27.68	46	430	1	419	9.0e-27	115	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
649912567	303	55.59	1	302	1	282	1.0e-99	356	COG0190	5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase	283
649912568	224	29.15	1	222	2	193	3.0e-32	131	COG0237	Dephospho-CoA kinase	201
649912569	407	40.92	86	404	40	345	2.0e-59	223	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
649912570	200	49.75	1	198	1	198	9.0e-65	239	COG0299	Folate-dependent phosphoribosylglycinamide formyltransferase PurN	200
649912571	368	52.94	26	365	1	339	5.0e-117	414	COG0150	Phosphoribosylaminoimidazole (AIR) synthetase	345
649912572	432	59.21	4	432	3	430	0.0e+00	582	COG0001	Glutamate-1-semialdehyde aminotransferase	432
649912573	203	55.34	1	203	2	203	4.0e-73	267	COG0605	Superoxide dismutase	204
649912574	807	21.27	39	699	3	612	7.0e-65	242	COG3387	Glucoamylase (glucan-1,4-alpha-glucosidase), GH15 family	612
649912575	660	56.89	1	659	2	663	0.0e+00	934	COG0021	Transketolase	663
649912577	156	48	1	149	1	149	6.0e-42	163	COG0698	Ribose 5-phosphate isomerase RpiB	151
649912578	285	38.19	2	196	1	199	3.0e-45	175	COG0300	Short-chain dehydrogenase	265
649912579	204	24.14	1	190	1	201	7.0e-16	77.3	COG1011	FMN phosphatase YigB, HAD superfamily	229
649912580	301	55.48	1	301	1	299	3.0e-112	398	COG1023	6-phosphogluconate dehydrogenase (decarboxylating)	300
649912581	510	50.71	19	508	1	481	0.0e+00	630	COG0364	Glucose-6-phosphate 1-dehydrogenase	483
649912582	268	37.4	11	251	5	237	4.0e-49	188	COG0363	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase	238
649912583	350	34.74	2	332	8	319	8.0e-73	267	COG0837	Glucokinase	320
649912584	855	26.76	27	832	19	847	8.0e-111	395	COG0308	Aminopeptidase N	859
649912585	925	35.2	613	916	2	280	1.0e-61	232	COG2333	Metal-dependent hydrolase, beta-lactamase superfamily II	293
649912586	450	30.73	6	444	6	432	1.0e-67	251	COG2265	tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family	432
649912588	283	45.56	4	261	1	251	5.0e-67	247	COG1521	Pantothenate kinase type III	251
649912589	269	38.84	26	263	1	233	1.0e-42	166	COG0340	Biotin-(acetyl-CoA carboxylase) ligase	238
649912590	298	42.01	8	295	6	279	6.0e-69	254	COG0157	Nicotinate-nucleotide pyrophosphorylase	280
649912592	932	48.82	5	930	1	875	0.0e+00	1089	COG0525	Valyl-tRNA synthetase	877
649912594	393	30	124	391	43	296	1.0e-28	121	COG2382	Enterochelin esterase or related enzyme	299
649912595	596	30.69	118	306	29	214	1.0e-27	118	COG4105	Outer membrane protein assembly factor BamD, BamD/ComL family	254
649912596	222	51.6	1	219	3	220	9.0e-73	266	COG0036	Pentose-5-phosphate-3-epimerase	220
649912598	460	36.93	11	460	3	454	2.0e-82	299	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
649912599	475	39.7	19	473	4	454	6.0e-111	394	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
649912602	413	35.48	23	392	2	323	3.0e-76	279	COG0042	tRNA-dihydrouridine synthase	323
649912603	78	47.95	3	72	2	74	1.0e-17	81.5	COG0254	Ribosomal protein L31	75
649912604	261	23.91	33	261	54	254	8.0e-24	104	COG1484	DNA replication protein DnaC	254
649912605	292	61.32	4	290	2	287	3.0e-117	414	COG1210	UTP-glucose-1-phosphate uridylyltransferase	291
649912606	583	20.92	9	577	5	584	7.0e-34	138	COG4805	Uncharacterized conserved protein, DUF885 familyt	588
649912607	1210	41.36	25	1202	4	1134	0.0e+00	1112	COG1197	Transcription-repair coupling factor (superfamily II helicase)	1139
649912608	493	55.21	14	491	5	481	0.0e+00	657	COG0064	Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit	483
649912611	113	35.14	1	74	8	81	1.0e-10	58.5	COG2331	Predicted nucleic acid-binding protein, contains Zn-ribbon domain	82
649912612	537	48.14	1	319	4	322	1.0e-85	311	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
649912613	386	41.85	1	386	1	386	1.0e-103	369	COG0754	Glutathionylspermidine synthase	387
649912615	391	39.19	1	388	2	383	2.0e-88	319	COG0075	Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism protein PucG	383
649912616	157	37.42	1	154	1	148	2.0e-24	105	COG1610	Uncharacterized conserved protein YqeY	148
649912617	214	30	22	155	4	150	3.0e-19	88.9	COG0328	Ribonuclease HI	154
649912618	322	33.93	1	319	3	317	1.0e-55	210	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
649912620	411	27.7	57	411	36	386	3.0e-57	216	COG4289	Uncharacterized protein	458
649912621	502	24.75	7	488	4	485	3.0e-40	160	COG0591	Na+/proline symporter	493
649912623	290	53.29	128	279	1	152	3.0e-47	181	COG0054	6,7-dimethyl-8-ribityllumazine synthase (Riboflavin synthase beta chain)	152
649912624	146	31.51	1	146	7	151	1.0e-26	111	COG0781	Transcription termination factor NusB	151
649912625	315	51.82	11	310	19	320	3.0e-100	358	COG0158	Fructose-1,6-bisphosphatase	326
649912627	260	37.21	1	249	1	251	2.0e-44	172	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
649912628	175	26.57	1	143	3	145	6.0e-06	43.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
649912631	879	18.7	556	879	70	419	4.0e-13	70.9	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
649912632	294	29.75	11	293	4	312	2.0e-53	202	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
649912633	219	20	11	208	1	200	2.0e-10	59.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
649912634	345	32.56	1	341	3	337	8.0e-75	274	COG2055	Malate/lactate/ureidoglycolate dehydrogenase, LDH2 family	349
649912639	293	25.34	1	292	3	291	5.0e-23	102	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
649912640	316	42.14	3	311	2	311	5.0e-57	214	COG0451	Nucleoside-diphosphate-sugar epimerase	314
649912642	466	36.87	18	465	7	458	1.0e-98	354	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
649912643	406	37.26	10	365	96	457	4.0e-84	305	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
649912644	381	28.46	1	378	1	380	6.0e-33	135	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649912645	437	16.88	122	436	69	381	2.0e-07	50.8	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649912647	358	24.73	1	355	1	376	6.0e-39	155	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649912648	389	22.62	1	375	9	395	4.0e-18	86.1	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
649912649	458	46.19	262	457	33	225	1.0e-58	221	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
649912650	317	29.18	83	310	24	242	2.0e-25	109	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
649912651	313	37.4	1	261	9	269	3.0e-46	178	COG3267	Type II secretory pathway, component ExeA (predicted ATPase)	269
649912652	506	18.95	9	455	14	458	5.0e-24	105	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
649912654	212	34.38	26	212	15	204	1.0e-23	103	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
649912657	764	20.63	159	379	21	243	4.0e-08	53.8	COG3063	Tfp pilus assembly protein PilF	250
649912660	509	23.27	32	428	10	400	2.0e-21	97.1	COG1807	4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferase of PMT family	535
649912663	539	37.09	13	363	2	357	2.0e-77	283	COG0793	C-terminal processing protease CtpA/Prc, contains a PDZ domain	406
649912664	645	21.1	76	371	22	313	2.0e-11	64.7	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
649912665	327	34.64	38	315	22	286	2.0e-36	146	COG3481	3'-5' exoribonuclease YhaM, can participate in 23S rRNA maturation,  HD superfamily	287
649912668	393	43.56	1	387	8	369	7.0e-109	387	COG0082	Chorismate synthase	369
649912669	169	52.1	1	165	2	168	2.0e-52	198	COG0242	Peptide deformylase	168
649912670	310	48.7	1	307	2	307	2.0e-98	352	COG0223	Methionyl-tRNA formyltransferase	307
649912671	419	32.43	99	418	1	354	4.0e-56	212	COG0144	16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family	355
649912672	298	27.63	32	257	2	219	1.0e-19	90.8	COG2815	PASTA domain, binds beta-lactams	303
649912673	478	34.68	23	317	14	302	9.0e-56	211	COG0053	Divalent metal cation (Fe/Co/Zn/Cd) transporter	304
649912674	250	39.24	13	244	4	235	4.0e-59	221	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
649912675	372	46.45	1	359	1	360	3.0e-105	375	COG0337	3-dehydroquinate synthetase	360
649912676	310	24.16	46	309	1	254	2.0e-31	130	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
649912678	260	33.74	21	257	8	249	1.0e-37	150	COG0805	Sec-independent protein secretion pathway component TatC	255
649912679	165	33.33	1	66	3	68	3.0e-12	64.6	COG1826	Sec-independent protein translocase protein TatA	94
649912680	142	26.52	1	132	1	114	1.0e-11	62.7	COG4911	Uncharacterized protein	123
649912681	219	42.13	5	216	10	225	2.0e-40	159	COG1272	Predicted membrane channel-forming protein YqfA, hemolysin III family	226
649912682	335	30.67	8	316	5	299	5.0e-32	131	COG0657	Acetyl esterase/lipase	312
649912683	168	31.62	2	133	1	131	2.0e-22	98.4	COG0563	Adenylate kinase or related kinase	178
649912685	160	29.58	1	141	1	141	1.0e-21	95.8	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
649912686	375	21.94	43	298	51	318	5.0e-07	49.1	COG2706	6-phosphogluconolactonase, cycloisomerase 2 family	346
649912687	655	37.78	1	655	1	638	0.0e+00	531	COG0323	DNA mismatch repair ATPase MutL	638
649912689	229	44.64	8	227	2	221	3.0e-59	222	COG0283	Cytidylate kinase	222
649912690	66	55.22	1	66	1	67	2.0e-20	90.6	COG1278	Cold shock protein, CspA family	67
649912693	108	35.78	1	108	2	110	2.0e-06	44	COG1950	Uncharacterized membrane protein YvlD, DUF360 family	120
649912694	559	21.37	68	430	46	391	6.0e-15	76.4	COG2814	Predicted arabinose efflux permease, MFS family	394
649912696	342	32.46	1	340	1	325	3.0e-58	219	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
649912699	297	23.33	1	281	1	294	1.0e-27	117	COG0451	Nucleoside-diphosphate-sugar epimerase	314
649912700	335	34.29	197	301	18	122	2.0e-21	96.9	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
649912701	550	23.98	205	405	2	204	2.0e-08	54.2	COG2755	Lysophospholipase L1 or related esterase	216
649912703	843	47.13	33	839	75	905	0.0e+00	919	COG0567	2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes	906
649912704	438	21.51	13	437	1	403	1.0e-37	150	COG1819	UDP:flavonoid glycosyltransferase YjiC, YdhE family	406
649912706	369	28.66	27	360	7	332	6.0e-40	158	COG2855	Uncharacterized membrane protein YadS	334
649912708	547	60.92	26	547	2	522	0.0e+00	686	COG0033	Phosphoglucomutase	524
649912710	502	20.99	33	219	38	296	2.0e-05	44.5	COG4225	Rhamnogalacturonyl hydrolase YesR	357
649912714	412	44.04	1	411	1	403	3.0e-102	365	COG1972	Nucleoside permease NupC	404
649912715	279	42.38	9	272	4	262	2.0e-62	232	COG0005	Purine nucleoside phosphorylase	262
649912716	212	43.9	10	204	6	209	2.0e-51	195	COG0572	Uridine kinase	218
649912718	274	29.15	20	274	16	284	1.0e-30	126	COG3176	Putative hemolysin	292
649912719	164	21.43	6	150	13	162	1.0e-03	36.4	COG3216	Uncharacterized conserved protein, DUF2062 family	184
649912721	474	26.75	23	463	1	375	1.0e-54	207	COG1488	Nicotinic acid phosphoribosyltransferase	405
649912723	62	60	1	60	2	61	2.0e-17	80.6	COG1476	DNA-binding transcriptional regulator, XRE-family HTH domain	68
649912724	354	34.03	8	337	7	318	3.0e-72	265	COG1899	Deoxyhypusine synthase	318
649912725	441	47.37	1	437	2	435	1.0e-129	456	COG0213	Thymidine phosphorylase	435
649912726	138	43.09	12	134	8	127	3.0e-30	124	COG0295	Cytidine deaminase	134
649912727	1600	32.94	18	945	2	808	0.0e+00	681	COG1201	Lhr-like helicase	814
649912728	301	30.07	1	279	1	273	4.0e-50	191	COG0266	Formamidopyrimidine-DNA glycosylase	273
649912729	394	23.75	1	361	7	363	1.0e-15	78.3	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
649912730	843	36.91	155	779	59	655	0.0e+00	476	COG0744	Membrane carboxypeptidase (penicillin-binding protein)	661
649912731	613	38.74	29	609	1	500	2.0e-128	453	COG0442	Prolyl-tRNA synthetase	500
649912732	290	30.33	160	268	12	133	2.0e-13	70.3	COG1225	Peroxiredoxin	157
649912733	325	47.47	13	209	10	201	3.0e-48	185	COG0794	D-arabinose 5-phosphate isomerase GutQ	202
649912734	200	27.7	63	197	7	152	1.0e-12	66.8	COG1225	Peroxiredoxin	157
649912736	498	36.84	3	486	5	470	2.0e-119	423	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
649912738	124	41.41	1	124	1	128	4.0e-29	120	COG3744	PIN domain nuclease, a component of toxin-antitoxin system (PIN domain)	130
649912739	202	49.36	1	152	1	155	1.0e-46	179	COG0245	2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	159
649912740	237	41.53	1	236	3	229	6.0e-57	213	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	230
649912742	358	34.6	20	255	21	251	2.0e-33	136	COG0037	tRNA(Ile)-lysidine synthase TilS/MesJ	298
649912743	639	55.48	9	602	1	595	0.0e+00	714	COG0465	ATP-dependent Zn proteases	596
649912744	169	26.83	3	162	7	154	1.0e-03	36.4	COG2980	Outer membrane lipoprotein LptE/RlpB (LPS assembly)	178
649912745	263	33.33	37	263	2	236	3.0e-33	135	COG0412	Dienelactone hydrolase	236
649912747	643	29.95	34	643	13	562	3.0e-80	293	COG2936	Predicted acyl esterase	563
649912749	392	24.39	11	377	2	334	8.0e-30	125	COG1466	DNA polymerase III, delta subunit	334
649912750	109	35.92	4	106	3	104	7.0e-16	75.6	COG1695	DNA-binding transcriptional regulator, PadR family	138
649912752	182	34.81	5	180	17	191	4.0e-29	121	COG5516	Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding	196
649912753	317	27.46	39	315	5	282	1.0e-20	94	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
649912755	248	50	3	245	2	250	1.0e-47	183	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
649912757	360	62.11	1	282	3	279	9.0e-83	300	COG0468	RecA/RadA recombinase	279
649912758	137	29.03	10	133	3	123	7.0e-16	76.4	COG3682	Predicted transcriptional regulator	123
649912759	447	20.81	8	339	1	332	1.0e-17	85	COG4219	Signal transducer regulating beta-lactamase production, contains  metallopeptidase domain	337
649912760	226	22.22	67	201	37	160	3.0e-04	38.8	COG3678	Periplasmic protein refolding chaperone Spy/CpxP family	160
649912762	203	36.94	34	190	22	172	2.0e-22	98.6	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
649912763	285	22.12	37	231	42	207	2.0e-10	60	COG3485	Protocatechuate 3,4-dioxygenase beta subunit	226
649912764	180	51.61	5	159	4	157	5.0e-59	220	COG0669	Phosphopantetheine adenylyltransferase	159
649912765	466	29.84	34	466	17	410	8.0e-60	224	COG2124	Cytochrome P450	411
649912766	390	39.95	5	390	2	393	3.0e-99	355	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
649912767	477	32.14	1	471	4	457	2.0e-95	343	COG1109	Phosphomannomutase	464
649912768	217	37	8	197	4	203	9.0e-34	136	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
649912769	246	46.47	7	246	5	243	5.0e-65	240	COG1212	CMP-2-keto-3-deoxyoctulosonic acid synthetase	247
649912771	423	27.63	4	406	1	403	4.0e-43	169	COG0793	C-terminal processing protease CtpA/Prc, contains a PDZ domain	406
649912772	823	38.46	39	728	13	727	0.0e+00	639	COG5009	Membrane carboxypeptidase/penicillin-binding protein	797
649912773	331	36.13	4	313	2	303	6.0e-68	251	COG0196	FAD synthase	304
649912774	271	27.7	5	271	6	266	2.0e-33	136	COG1235	Phosphoribosyl 1,2-cyclic phosphodiesterase	269
649912776	322	24.91	26	296	25	277	7.0e-33	134	COG0354	Folate-binding Fe-S cluster repair protein YgfZ, possible role in tRNA modification	305
649912778	288	45.63	2	248	14	262	7.0e-73	267	COG0005	Purine nucleoside phosphorylase	262
649912779	315	24.92	2	302	1	308	5.0e-17	81.8	COG0524	Sugar or nucleoside kinase, ribokinase family	311
649912781	271	36.2	2	265	1	271	6.0e-50	191	COG0253	Diaminopimelate epimerase	272
649912782	310	38.87	1	309	2	312	2.0e-67	249	COG1619	Muramoyltetrapeptide carboxypeptidase LdcA (peptidoglycan recycling)	313
649912783	481	38.45	1	472	4	459	5.0e-109	388	COG0773	UDP-N-acetylmuramate-alanine ligase	459
649912784	236	32.03	7	230	2	225	2.0e-23	102	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
649912786	262	40	3	206	2	211	1.0e-33	137	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
649912790	534	19.56	28	419	15	413	6.0e-12	65.9	COG1807	4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferase of PMT family	535
649912793	345	35.41	1	342	1	350	3.0e-75	275	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
649912794	401	50.78	8	391	4	384	1.0e-117	416	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
649912796	413	21.17	30	352	2	344	6.0e-12	65.7	COG2706	6-phosphogluconolactonase, cycloisomerase 2 family	346
649912798	691	41.25	42	691	6	654	0.0e+00	611	COG3590	Predicted metalloendopeptidase	654
649912799	214	25.71	7	207	5	214	8.0e-26	110	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
649912800	354	22.38	14	252	20	290	6.0e-10	58.9	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
649912804	243	36	2	239	1	249	5.0e-43	168	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
649912806	105	32.99	1	97	6	102	2.0e-12	64.1	COG1695	DNA-binding transcriptional regulator, PadR family	138
649912807	889	18.43	499	889	1	419	4.0e-16	80.6	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
649912811	270	23.38	8	211	1	218	2.0e-13	69.9	COG2908	UDP-2,3-diacylglucosamine pyrophosphatase LpxH	237
649912812	384	35.01	1	382	6	396	2.0e-89	322	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
649912815	255	38.34	1	244	1	250	8.0e-44	170	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
649912817	214	38.28	3	210	2	205	5.0e-46	177	COG0288	Carbonic anhydrase	207
649912818	221	26.17	52	157	16	112	3.0e-03	35.7	COG5395	Uncharacterized membrane protein	131
649912819	516	29.7	19	498	19	511	1.0e-75	277	COG0659	Sulfate permease or related transporter, MFS superfamily	554
649912820	217	40.1	1	205	4	205	1.0e-42	166	COG0288	Carbonic anhydrase	207
649912823	304	33.21	20	293	28	295	4.0e-53	201	COG3781	Predicted membrane chloride channel, bestrophin family	306
649912824	233	32.85	20	225	8	213	1.0e-28	119	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
649912825	550	45.14	23	529	5	517	1.0e-127	450	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
649912827	414	17.06	61	399	56	381	2.0e-07	50.6	COG2814	Predicted arabinose efflux permease, MFS family	394
649912828	238	51.34	3	225	1	224	8.0e-75	273	COG1136	ABC-type lipoprotein export system, ATPase component	226
649912830	126	48.41	1	126	1	125	3.0e-33	134	COG0736	Phosphopantetheinyl transferase (holo-ACP synthase)	127
649912831	361	19.8	14	314	10	289	2.0e-17	83.6	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
649912833	170	50.57	1	170	3	175	1.0e-45	176	COG2110	O-acetyl-ADP-ribose deacetylase (regulator of RNase III), contains Macro domain	179
649912834	380	41.56	130	283	33	183	3.0e-28	119	COG1386	Chromosome segregation and condensation protein ScpB	184
649912835	301	45.24	12	260	1	241	1.0e-64	240	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
649912838	158	56.96	1	158	4	161	3.0e-60	224	COG0225	Peptide methionine sulfoxide reductase MsrA	174
649912839	453	22.4	29	444	12	398	1.0e-23	105	COG1228	Imidazolonepropionase or related amidohydrolase	406
649912840	309	21.65	28	297	3	283	2.0e-12	67.1	COG1216	Glycosyltransferase, GT2 family	305
649912841	467	16.51	35	462	10	414	1.0e-03	38.5	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
649912843	501	36.95	5	450	3	421	2.0e-100	359	COG0513	Superfamily II DNA and RNA helicase	513
649912845	186	30.32	16	166	21	175	3.0e-17	81.7	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
649912846	376	23.4	7	374	1	374	3.0e-31	129	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649912847	246	54.73	4	245	3	230	5.0e-67	247	COG0689	Ribonuclease PH	230
649912848	512	45.82	35	511	1	457	5.0e-130	458	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
649912851	731	28.79	137	727	15	559	3.0e-73	270	COG2936	Predicted acyl esterase	563
649912854	136	20.59	4	135	6	131	4.0e-04	37.2	COG5485	Predicted ester cyclase	131
649912857	506	24.11	20	464	1	416	2.0e-56	213	COG1239	Mg-chelatase subunit ChlI	423
649912858	232	28.12	10	232	10	221	1.0e-27	116	COG1285	Uncharacterized membrane protein YhiD, involved in acid resistance	221
649912860	172	44.08	1	152	2	152	1.0e-37	149	COG1607	Acyl-CoA hydrolase	157
649912861	283	42.73	17	239	49	265	7.0e-48	184	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
649912862	358	31.91	4	348	1	339	2.0e-53	203	COG1420	Transcriptional regulator of heat shock response	346
649912863	180	32.02	1	174	15	192	4.0e-27	114	COG0576	Molecular chaperone GrpE (heat shock protein)	193
649912864	378	52.39	6	378	1	370	5.0e-128	451	COG0484	DnaJ-class molecular chaperone with C-terminal Zn finger domain	371
649912865	237	35.56	20	237	20	244	6.0e-44	170	COG1385	16S rRNA U1498 N3-methylase RsmE	246
649912866	478	45.61	179	474	1	262	9.0e-79	287	COG1760	L-serine deaminase	262
649912868	527	51.66	14	523	1	489	0.0e+00	568	COG0606	Predicted ATPase with chaperone activity	490
649912870	416	71.22	1	415	4	420	0.0e+00	682	COG1158	Transcription termination factor Rho	422
649912871	324	48.58	30	275	2	245	2.0e-67	249	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
649912872	606	58.4	8	606	12	606	0.0e+00	828	COG1274	Phosphoenolpyruvate carboxykinase, GTP-dependent	608
649912873	115	30.36	1	110	1	105	4.0e-09	53.4	COG3254	L-rhamnose mutarotase	105
649912874	346	40.13	13	314	2	300	4.0e-80	291	COG0031	Cysteine synthase	300
649912875	412	27.79	12	411	6	426	3.0e-44	173	COG0038	H+/Cl- antiporter ClcA	443
649912876	108	36.63	3	101	6	106	4.0e-15	73.1	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
649912877	416	24.62	31	404	6	384	2.0e-36	147	COG3182	Uncharacterized iron-regulated membrane protein	442
649912880	432	21.86	87	332	58	288	8.0e-10	58.7	COG4975	Glucose uptake protein GlcU	288
649912881	338	39.94	3	333	1	329	2.0e-79	289	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
649912885	416	33.22	94	390	3	299	2.0e-43	170	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
649912886	736	30.73	47	423	11	393	7.0e-60	226	COG1472	Periplasmic beta-glucosidase and related glycosidases	397
649912888	486	49.66	49	484	3	433	0.0e+00	552	COG3538	Meiotically up-regulated gene 157 (Mug157) protein (function unknown)	434
649912889	430	22.64	5	423	24	434	2.0e-28	120	COG2271	Sugar phosphate permease	448
649912891	207	44.29	4	205	1	210	7.0e-46	177	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
649912893	252	33.14	78	246	43	203	8.0e-25	107	COG0684	Regulator of RNase E activity RraA	210
649912894	433	22.28	50	429	11	373	9.0e-24	104	COG1921	Seryl-tRNA(Sec) selenium transferase	395
649912895	167	32.56	48	167	4	128	7.0e-17	80.3	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
649912896	542	24.68	55	341	5	296	1.0e-29	124	COG1921	Seryl-tRNA(Sec) selenium transferase	395
649912897	519	34.12	56	431	2	371	4.0e-68	252	COG3964	Predicted amidohydrolase	386
649912899	232	40.18	6	220	2	215	2.0e-53	202	COG1136	ABC-type lipoprotein export system, ATPase component	226
649912900	417	19.39	1	415	8	406	4.0e-16	79.5	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
649912901	235	41.29	17	216	5	203	1.0e-45	176	COG3142	Copper homeostasis protein CutC	241
649912904	239	39.53	23	237	1	210	4.0e-48	184	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
649912905	524	28.72	324	511	2	189	1.0e-27	118	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
649912906	257	55.06	4	249	3	246	1.0e-74	273	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
649912907	871	27.61	8	863	3	858	5.0e-127	449	COG1674	DNA segregation ATPase FtsK/SpoIIIE and related proteins	858
649912909	144	30.58	1	120	2	122	5.0e-17	80.4	COG4270	Uncharacterized membrane protein	131
649912910	289	36.14	1	285	3	267	5.0e-48	184	COG1968	Undecaprenyl pyrophosphate phosphatase UppP	270
649912912	334	45.68	4	325	6	319	2.0e-85	309	COG1171	Threonine dehydratase	347
649912914	557	45.03	8	555	7	555	0.0e+00	545	COG0595	mRNA degradation ribonuclease J1/J2	555
649912916	282	40.61	3	282	1	269	1.0e-44	173	COG2171	Tetrahydrodipicolinate N-succinyltransferase	271
649912917	339	53.24	1	339	1	299	5.0e-112	397	COG1023	6-phosphogluconate dehydrogenase (decarboxylating)	300
649912918	394	33.25	1	389	1	384	3.0e-69	255	COG0498	Threonine synthase	411
649912920	548	25.06	48	477	83	481	6.0e-53	202	COG5434	Polygalacturonase	542
649912921	311	44.3	2	298	1	296	2.0e-75	275	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
649912922	205	32.07	8	190	13	196	2.0e-33	135	COG3548	Uncharacterized membrane protein	197
649912924	421	41.73	19	420	3	384	1.0e-107	383	COG2309	Leucyl aminopeptidase (aminopeptidase T)	385
649912925	123	26.67	11	120	15	122	1.0e-03	35.3	COG3324	Predicted enzyme related to lactoylglutathione lyase	127
649912926	227	32.58	1	221	3	264	6.0e-38	150	COG0289	Dihydrodipicolinate reductase	266
649912927	479	37.61	7	459	2	447	3.0e-100	359	COG0527	Aspartokinase	447
649912928	361	40.16	5	346	3	334	2.0e-80	292	COG0136	Aspartate-semialdehyde dehydrogenase	334
649912931	155	53.9	1	154	1	154	7.0e-47	179	COG1327	Transcriptional regulator NrdR, contains Zn-ribbon and ATP-cone domains	156
649912933	237	29.55	15	224	59	278	7.0e-18	84.4	COG0741	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)	296
649912934	309	27.63	5	308	1	262	3.0e-39	155	COG0561	Hydroxymethylpyrimidine pyrophosphatase and other HAD family phosphatases	264
649912935	308	21.18	9	289	8	282	4.0e-06	45.9	COG2962	Uncharacterized membrane protein RarD, contains two EamA domains	293
649912939	391	28.57	3	294	2	283	1.0e-35	143	COG1792	Cell shape-determining protein MreC	284
649912940	354	64.5	19	351	1	338	2.0e-122	432	COG1077	Actin-like ATPase involved in cell morphogenesis	342
649912941	371	61.73	1	371	1	371	0.0e+00	493	COG0686	Alanine dehydrogenase	371
649912942	791	25.1	16	752	8	689	7.0e-82	299	COG5000	Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation	712
649912943	456	47.39	1	456	4	460	0.0e+00	475	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
649912944	349	46.81	1	328	2	297	3.0e-96	345	COG1159	GTPase Era, involved in 16S rRNA processing	298
649912945	435	26.5	1	435	2	428	2.0e-55	210	COG1253	Hemolysin or related protein, contains CBS domains	429
649912946	156	38.46	9	143	9	151	5.0e-26	110	COG0319	ssRNA-specific RNase YbeY, 16S rRNA maturation enzyme	153
649912947	345	49.37	11	322	25	339	2.0e-93	336	COG1702	Phosphate starvation-inducible protein PhoH, predicted ATPase	348
649912948	86	40	4	82	2	81	4.0e-07	46.6	COG2261	Uncharacterized membrane protein YeaQ/YmgE, transglycosylase-associated protein family	82
649912950	91	37.5	1	88	1	88	4.0e-10	56.1	COG0268	Ribosomal protein S20	88
649912951	653	31.96	28	611	23	598	2.0e-113	403	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
649912952	366	40.87	8	366	12	375	9.0e-70	257	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
649912953	256	23.77	35	256	38	243	2.0e-11	63.4	COG2968	Uncharacterized conserved protein YggE, contains kinase-interacting SIMPL domain	243
649912954	1201	40.59	795	1200	74	480	5.0e-89	323	COG1530	Ribonuclease G or E	487
649912956	434	47.28	22	422	14	410	1.0e-87	317	COG0738	Fucose permease	422
649912957	452	32.4	53	431	26	369	1.0e-49	191	COG0006	Xaa-Pro aminopeptidase	384
649912959	547	25.87	35	406	5	365	2.0e-35	144	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
649912960	321	43.7	54	321	47	312	2.0e-48	186	COG0657	Acetyl esterase/lipase	312
649912961	394	29.31	14	345	5	350	7.0e-40	158	COG0644	Dehydrogenase (flavoprotein)	396
649912963	165	21.68	6	140	17	146	4.0e-04	37.6	COG4243	Uncharacterized membrane protein	156
649912965	706	39.15	245	512	2	282	6.0e-65	242	COG0169	Shikimate 5-dehydrogenase	283
649912966	163	34.94	4	163	2	167	1.0e-29	122	COG0629	Single-stranded DNA-binding protein	167
649912968	125	24.27	16	118	1	100	5.0e-09	53.3	COG1965	Iron-binding protein CyaY, frataxin homolog	106
649912969	255	23.57	1	251	2	264	8.0e-18	84.4	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
649912970	333	34.98	52	333	4	248	3.0e-54	205	COG1496	Copper oxidase (laccase) domain	249
649912972	188	38.41	19	182	11	172	1.0e-25	109	COG2322	Uncharacterized membrane protein YozB, DUF420 family	177
649912973	317	34.82	5	316	1	302	1.0e-51	196	COG0109	Polyprenyltransferase (heme O synthase)	304
649912974	330	22.39	1	328	23	352	3.0e-23	102	COG0628	Predicted PurR-regulated permease PerM	355
649912975	191	42.69	22	189	3	167	2.0e-32	131	COG0703	Shikimate kinase	172
649912977	217	39.11	27	205	2	177	3.0e-33	135	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
649912978	350	42.4	12	257	10	252	1.0e-57	217	COG0476	Molybdopterin or thiamine biosynthesis adenylyltransferase	254
649912979	471	40.81	1	464	1	451	6.0e-97	348	COG0770	UDP-N-acetylmuramyl pentapeptide synthase	451
649912981	453	29.53	145	433	5	289	2.0e-45	176	COG2421	Acetamidase/formamidase	305
649912982	378	39.29	21	378	1	316	5.0e-52	198	COG0472	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase	319
649912983	452	47.9	3	452	5	448	0.0e+00	462	COG0771	UDP-N-acetylmuramoylalanine-D-glutamate ligase	448
649912984	363	40.93	3	361	10	371	1.0e-74	273	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
649912985	350	36.77	1	350	5	356	2.0e-80	292	COG0707	UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase	357
649912987	454	50.98	1	453	2	457	0.0e+00	542	COG0773	UDP-N-acetylmuramate-alanine ligase	459
649912988	458	20.37	66	331	15	260	5.0e-18	86.2	COG1589	Cell division septal protein FtsQ	269
649912989	407	38.63	1	407	1	418	2.0e-94	339	COG0849	Cell division ATPase FtsA	418
649912991	510	57.01	18	345	11	338	2.0e-100	360	COG0206	Cell division GTPase FtsZ	338
649912993	526	41.14	211	509	1	282	1.0e-55	210	COG0063	NAD(P)H-hydrate repair enzyme Nnr, NAD(P)H-hydrate dehydratase domain	284
649912994	152	44.44	11	145	1	131	3.0e-28	117	COG0802	tRNA A37 threonylcarbamoyladenosine biosynthesis protein TsaE	149
649912995	337	20.63	55	337	5	282	3.0e-21	95.9	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
649912996	318	37.34	13	314	22	326	1.0e-63	237	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
649912998	171	37.33	16	165	3	151	6.0e-32	130	COG0783	DNA-binding ferritin-like protein (oxidative damage protectant)	156
649912999	601	38.73	2	504	1	530	3.0e-118	419	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
649913000	362	24.06	1	339	30	365	2.0e-23	103	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
649913001	255	58.82	1	255	1	255	2.0e-98	352	COG0623	Enoyl-[acyl-carrier-protein] reductase (NADH)	259
649913002	125	34.53	3	120	5	143	2.0e-20	90.8	COG2947	Predicted RNA-binding protein, contains PUA-like domain	156
649913003	283	36.01	1	278	1	308	4.0e-67	247	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
649913005	238	24.44	10	224	15	225	8.0e-20	90.9	COG0860	N-acetylmuramoyl-L-alanine amidase	231
649913006	470	22.48	1	469	1	404	2.0e-34	140	COG4198	Uncharacterized conserved protein, DUF1015 family	405
649913007	524	18.24	60	495	59	501	4.0e-03	36.6	COG1807	4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferase of PMT family	535
649913010	198	35.65	2	193	4	219	1.0e-24	106	COG1214	tRNA A37 threonylcarbamoyladenosine modification protein TsaB	220
649913011	144	33.06	25	140	49	172	1.0e-12	65.8	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
649913012	208	35.71	1	201	28	235	3.0e-34	138	COG0688	Phosphatidylserine decarboxylase	239
649913013	281	34.26	8	256	1	222	5.0e-38	151	COG1183	Phosphatidylserine synthase	234
649913014	344	24.4	7	334	3	333	2.0e-25	109	COG0136	Aspartate-semialdehyde dehydrogenase	334
649913016	216	14.83	1	207	6	193	2.0e-03	36.1	COG2834	Outer membrane lipoprotein-sorting protein	211
649913018	440	57.24	1	439	1	429	0.0e+00	577	COG0172	Seryl-tRNA synthetase	429
649913020	309	40.65	8	309	1	309	3.0e-67	248	COG0167	Dihydroorotate dehydrogenase	310
649913022	530	59.4	7	529	2	515	0.0e+00	689	COG0138	AICAR transformylase/IMP cyclohydrolase PurH	515
649913024	381	35.95	15	370	14	403	1.0e-67	250	COG0232	dGTP triphosphohydrolase	412
649913027	1184	28.98	762	1173	10	426	1.0e-48	188	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
649913029	219	22.75	3	203	2	210	3.0e-21	95.4	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
649913030	544	37.3	225	541	1	300	2.0e-55	210	COG0492	Thioredoxin reductase	305
649913032	367	31.1	1	326	2	322	6.0e-62	231	COG1477	Thiamine biosynthesis lipoprotein ApbE	337
649913038	197	24.22	42	165	1	127	1.0e-10	60.3	COG0526	Thiol-disulfide isomerase or thioredoxin	127
649913040	542	44.51	16	542	2	475	0.0e+00	532	COG0043	3-polyprenyl-4-hydroxybenzoate decarboxylase	477
649913042	167	39.04	4	149	9	139	2.0e-32	132	COG1143	Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)	172
649913044	426	34.9	7	405	4	398	1.0e-77	284	COG0498	Threonine synthase	411
649913045	93	27.78	2	91	1	84	4.0e-07	46.5	COG1977	Molybdopterin converting factor, small subunit	84
649913048	820	58.54	23	797	6	782	0.0e+00	1073	COG0466	ATP-dependent Lon protease, bacterial type	782
649913049	429	63.03	14	416	1	390	0.0e+00	604	COG1219	ATP-dependent protease Clp, ATPase subunit	408
649913050	198	71.43	1	196	1	193	3.0e-78	284	COG0740	ATP-dependent protease ClpP, protease subunit	200
649913051	471	32.94	41	460	8	414	5.0e-63	235	COG0544	FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)	441
649913053	237	28.88	4	235	1	200	5.0e-26	111	COG1573	Uracil-DNA glycosylase	202
649913054	105	32.94	1	85	2	86	6.0e-07	45.7	COG4980	Gas vesicle protein	115
649913055	826	49.75	4	804	1	777	0.0e+00	866	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
649913056	229	41.74	9	225	1	218	1.0e-66	246	COG1136	ABC-type lipoprotein export system, ATPase component	226
649913058	897	30.41	28	893	29	859	1.0e-110	394	COG2844	UTP:GlnB (protein PII) uridylyltransferase	867
649913059	112	58.93	1	112	1	112	3.0e-33	133	COG0347	Nitrogen regulatory protein PII	112
649913060	495	55.08	71	493	1	407	3.0e-121	429	COG0004	Ammonia channel protein AmtB	409
649913062	205	56.29	36	201	5	170	3.0e-64	237	COG0377	NADH:ubiquinone oxidoreductase 20 kD subunit (chhain B) or related Fe-S oxidoreductase	194
649913063	540	19.46	350	494	17	159	2.0e-04	41	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
649913064	669	18.82	8	337	11	332	2.0e-05	45	COG4447	Uncharacterized protein related to plant photosystem II stability/assembly factor	339
649913066	611	38.12	33	601	5	586	0.0e+00	501	COG4805	Uncharacterized conserved protein, DUF885 familyt	588
649913067	123	24.6	1	117	2	124	1.0e-10	59.2	COG3324	Predicted enzyme related to lactoylglutathione lyase	127
649913068	467	52.18	12	467	1	407	0.0e+00	498	COG0538	Isocitrate dehydrogenase	407
649913069	495	33.63	12	451	4	400	8.0e-94	337	COG0579	L-2-hydroxyglutarate oxidase LhgO	429
649913071	173	46.43	9	170	1	156	5.0e-45	173	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
649913072	283	40.8	94	259	1	157	4.0e-35	141	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
649913073	373	33.52	17	371	3	310	7.0e-66	244	COG2355	Zn-dependent dipeptidase, microsomal dipeptidase homolog	313
649913076	331	20.34	41	322	6	262	1.0e-09	57.7	COG1409	3',5'-cyclic AMP phosphodiesterase CpdA	301
649913078	259	32.66	9	255	1	234	1.0e-54	206	COG0479	Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit	234
649913079	593	40.17	6	579	8	561	0.0e+00	493	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
649913080	266	20.69	29	139	17	131	4.0e-06	45.3	COG2009	Succinate dehydrogenase/fumarate reductase, cytochrome b subunit	132
649913081	198	45.64	4	198	4	190	1.0e-49	189	COG0127	Inosine/xanthosine triphosphate pyrophosphatase, all-alpha NTP-PPase family	194
649913082	312	33.99	11	301	1	306	8.0e-38	151	COG0524	Sugar or nucleoside kinase, ribokinase family	311
649913083	443	23.69	19	412	5	351	2.0e-34	140	COG1260	Myo-inositol-1-phosphate synthase	362
649913086	428	24.31	1	426	1	405	2.0e-42	167	COG1819	UDP:flavonoid glycosyltransferase YjiC, YdhE family	406
649913087	417	21.76	34	417	42	445	8.0e-16	78.7	COG2271	Sugar phosphate permease	448
649913088	386	19.15	7	374	15	409	1.0e-16	81.5	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
649913089	332	24.76	25	327	16	331	4.0e-39	155	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
649913090	420	43.35	4	409	1	361	1.0e-122	433	COG0821	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase IspG/GcpE	361
649913092	464	37.69	54	373	24	347	5.0e-68	252	COG5042	Purine nucleoside permease	349
649913094	473	23.89	231	449	40	257	3.0e-20	93.3	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
649913097	768	32.09	34	757	35	765	0.0e+00	483	COG3537	Putative alpha-1,2-mannosidase	768
649913098	164	28.04	45	151	17	123	2.0e-11	62.3	COG1846	DNA-binding transcriptional regulator, MarR family	126
649913099	324	36.88	7	130	2	138	4.0e-10	59.1	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
649913100	212	32.64	21	210	16	203	3.0e-19	88.4	COG0400	Predicted esterase	207
649913105	227	44.98	1	223	1	228	2.0e-52	199	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
649913106	470	29.81	144	464	21	331	1.0e-37	151	COG0642	Signal transduction histidine kinase	336
649913108	1035	30.95	19	1030	7	1008	0.0e+00	642	COG0841	Multidrug efflux pump subunit AcrB	1009
649913110	453	28.33	43	453	44	445	5.0e-28	119	COG1538	Outer membrane protein TolC	457
649913113	385	24.67	33	170	4	135	5.0e-10	59.1	COG1225	Peroxiredoxin	157
649913114	341	36.99	13	327	1	308	7.0e-75	274	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
649913115	459	24.38	10	459	8	481	2.0e-24	107	COG1345	Flagellar capping protein FliD	483
649913116	157	32.5	3	122	10	129	9.0e-14	69.6	COG1516	Flagellin-specific chaperone FliS	132
649913117	252	35.41	5	248	2	250	1.0e-43	169	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
649913118	276	30.32	1	276	7	278	1.0e-47	183	COG3618	Predicted metal-dependent hydrolase, TIM-barrel fold	279
649913120	394	32.9	8	394	4	371	2.0e-56	213	COG4299	Predicted acyltransferase	371
649913121	281	21.53	36	276	2	274	4.0e-17	82.2	COG1082	Sugar phosphate isomerase/epimerase	274
649913122	163	37.27	3	162	6	166	3.0e-35	141	COG4702	Uncharacterized protein, UPF0303 family	168
649913123	1029	29.02	40	542	9	457	1.0e-58	222	COG0277	FAD/FMN-containing dehydrogenase	459
649913124	163	28.16	46	144	25	126	9.0e-10	56.4	COG0526	Thiol-disulfide isomerase or thioredoxin	127
649913125	351	21.78	5	345	50	381	8.0e-14	71.5	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
649913126	428	21.13	11	415	25	432	1.0e-22	101	COG2271	Sugar phosphate permease	448
649913127	342	27.63	7	263	25	241	2.0e-25	110	COG2333	Metal-dependent hydrolase, beta-lactamase superfamily II	293
649913128	268	39.37	6	252	1	251	4.0e-47	181	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
649913129	349	38	1	343	2	350	6.0e-75	274	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
649913131	137	32.14	1	135	2	127	1.0e-17	82.3	COG0720	6-pyruvoyl-tetrahydropterin synthase	127
649913132	148	28.91	9	133	7	120	5.0e-12	63.8	COG0720	6-pyruvoyl-tetrahydropterin synthase	127
649913133	193	60.85	1	189	6	194	1.0e-75	275	COG0302	GTP cyclohydrolase I	195
649913134	291	33.45	3	277	16	257	2.0e-51	196	COG0130	tRNA U55 pseudouridine synthase TruB, may also work on U342 of tmRNA	271
649913135	247	29.61	67	247	9	214	7.0e-18	84.2	COG2755	Lysophospholipase L1 or related esterase	216
649913136	235	48.9	6	231	2	226	3.0e-73	268	COG1136	ABC-type lipoprotein export system, ATPase component	226
649913137	854	31.54	5	853	3	828	7.0e-122	431	COG3127	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component	829
649913138	141	38.14	4	121	2	119	6.0e-28	116	COG1733	DNA-binding transcriptional regulator, HxlR family	120
649913140	232	53.18	2	221	1	220	2.0e-69	255	COG0120	Ribose 5-phosphate isomerase	227
649913141	818	32.86	16	269	2	278	2.0e-40	161	COG0515	Serine/threonine protein kinase	384
649913143	264	41.87	28	262	9	250	2.0e-48	186	COG0631	Serine/threonine protein phosphatase PrpC	262
649913144	1142	23.41	4	1141	14	1188	5.0e-77	283	COG3523	Type VI protein secretion system component VasK	1188
649913145	238	26.09	6	210	38	238	2.0e-18	86.5	COG3455	Type VI protein secretion system component VasF	262
649913146	451	30.6	1	446	1	444	2.0e-68	253	COG3522	Predicted component of the type VI protein secretion system	446
649913148	456	33.26	1	445	1	442	1.0e-75	277	COG3522	Predicted component of the type VI protein secretion system	446
649913149	171	47.31	4	170	2	166	8.0e-46	176	COG3516	Predicted component of the type VI protein secretion system	169
649913150	499	56.48	1	494	1	491	0.0e+00	687	COG3517	Predicted component of the type VI protein secretion system	495
649913151	163	23.97	10	146	6	151	5.0e-09	54.2	COG3157	Type VI protein secretion system component Hcp (secreted cytotoxin)	162
649913152	630	24.75	6	296	6	289	1.0e-10	62	COG3515	Predicted component of the type VI protein secretion system	346
649913153	159	35.06	5	158	1	153	9.0e-23	99.6	COG3518	Predicted component of the type VI protein secretion system	157
649913154	613	38.66	1	610	1	618	0.0e+00	492	COG3519	Type VI protein secretion system component VasA	621
649913155	353	39.69	25	344	19	325	5.0e-76	278	COG3520	Predicted component of the type VI protein secretion system	335
649913156	887	41.86	11	856	1	767	0.0e+00	757	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
649913157	688	34.57	5	568	7	549	9.0e-108	384	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
649913158	353	20.48	7	287	3	284	8.0e-11	61.5	COG0451	Nucleoside-diphosphate-sugar epimerase	314
649913159	99	31.18	7	99	19	98	8.0e-08	48.7	COG0640	DNA-binding transcriptional regulator, ArsR family	110
649913165	266	30.43	31	260	14	235	3.0e-41	162	COG5255	Uncharacterized protein	239
649913170	509	28.43	19	501	35	551	7.0e-78	284	COG0747	ABC-type transport system, periplasmic component	556
649913171	391	39.9	1	388	2	367	3.0e-78	285	COG2377	1,6-Anhydro-N-acetylmuramate kinase	371
649913172	889	46.05	19	884	7	842	0.0e+00	824	COG0249	DNA mismatch repair ATPase MutS	843
649913174	431	26.35	1	423	1	401	2.0e-42	167	COG1819	UDP:flavonoid glycosyltransferase YjiC, YdhE family	406
649913175	432	27.93	1	422	1	400	2.0e-47	183	COG1819	UDP:flavonoid glycosyltransferase YjiC, YdhE family	406
649913176	438	27.61	1	427	1	406	2.0e-49	190	COG1819	UDP:flavonoid glycosyltransferase YjiC, YdhE family	406
649913177	272	21.48	1	255	1	251	1.0e-11	64.1	COG4137	ABC-type uncharacterized transport system, permease component	265
649913178	428	43.91	1	419	1	414	1.0e-112	400	COG0373	Glutamyl-tRNA reductase	414
649913179	350	39.44	1	348	2	304	4.0e-80	291	COG0181	Porphobilinogen deaminase	307
649913180	252	37.65	5	248	2	244	5.0e-38	151	COG1587	Uroporphyrinogen-III synthase	248
649913181	254	46.19	41	250	1	209	3.0e-67	248	COG0177	Endonuclease III	211
649913182	256	29.82	30	255	10	229	1.0e-38	153	COG3253	Chlorite dismutase	230
649913183	213	33.33	16	201	11	199	7.0e-34	137	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
649913184	392	18.9	1	324	2	316	3.0e-12	66.8	COG0701	Uncharacterized membrane protein YraQ, UPF0718 family	317
649913185	284	35.45	1	265	2	244	4.0e-46	178	COG1360	Flagellar motor protein MotB	244
649913186	256	36.61	1	253	1	254	2.0e-55	209	COG1291	Flagellar motor component MotA	266
649913187	82	44.83	1	58	1	58	3.0e-13	66.8	COG1582	Uncharacterized protein YlzI, FlbEa/FlbD family	67
649913188	399	27.59	5	399	3	360	4.0e-23	102	COG1344	Flagellin and related hook-associated protein FlgL	360
649913191	346	38.08	4	338	2	326	8.0e-57	214	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
649913192	165	23.62	38	160	37	162	2.0e-04	38.4	COG2318	Uncharacterized damage-inducible protein DinB (forms a four-helix bundle)	172
649913194	340	64.24	1	329	2	331	0.0e+00	495	COG0059	Ketol-acid reductoisomerase	338
649913195	205	42.51	1	167	3	162	2.0e-34	138	COG0440	Acetolactate synthase, small subunit	163
649913196	588	46.47	10	575	1	549	0.0e+00	580	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
649913197	564	48.5	7	563	10	570	0.0e+00	651	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
649913199	208	51.78	1	197	1	185	1.0e-63	236	COG0066	3-isopropylmalate dehydratase small subunit	191
649913200	487	57.2	2	469	1	423	0.0e+00	624	COG0065	Homoaconitase/3-isopropylmalate dehydratase large subunit	423
649913201	361	47.8	1	359	2	348	5.0e-106	377	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
649913202	393	51.05	9	386	1	375	3.0e-110	392	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
649913203	308	32.77	1	293	1	292	1.0e-31	130	COG0583	DNA-binding transcriptional regulator, LysR family	297
649913205	203	18.65	11	203	14	199	9.0e-03	33.8	COG3637	Opacity protein and related surface antigens	199
649913209	326	50.46	1	321	1	325	5.0e-129	454	COG1087	UDP-glucose 4-epimerase	329
649913212	654	47.59	79	639	1	528	0.0e+00	676	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
649913213	791	33.24	420	783	94	447	2.0e-59	224	COG5002	Signal transduction histidine kinase	459
649913214	179	22.77	67	165	29	129	1.0e-04	39.6	COG4319	Ketosteroid isomerase homolog	137
649913215	466	41.94	57	455	6	405	3.0e-76	279	COG1301	Na+/H+-dicarboxylate symporter	415
649913216	629	51.48	4	608	4	612	0.0e+00	780	COG1154	Deoxyxylulose-5-phosphate synthase	627
649913217	181	25	5	168	4	146	2.0e-11	62.8	COG4276	Ligand-binding SRPBCC domain	153
649913218	890	31.49	120	890	47	750	3.0e-117	416	COG4774	Outer membrane receptor for monomeric catechols	750
649913219	226	57.71	1	226	3	229	8.0e-86	309	COG3128	Predicted 2-oxoglutarate- and Fe(II)-dependent dioxygenase YbiX	229
649913221	169	28.97	20	164	7	147	2.0e-15	75.8	COG3305	Uncharacterized membrane protein, DUF2068 family	152
649913222	146	32.21	1	146	1	146	4.0e-20	90.7	COG2001	MraZ, DNA-binding transcriptional regulator and inhibitor of RsmH methyltransferase activity	146
649913223	319	49.68	5	299	6	314	1.0e-96	346	COG0275	16S rRNA C1402 N4-methylase RsmH	314
649913225	771	36.88	3	591	2	599	1.0e-123	437	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
649913227	506	39.38	21	502	9	475	2.0e-101	363	COG0769	UDP-N-acetylmuramyl tripeptide synthase	475
649913228	1102	20.93	343	1102	85	766	3.0e-63	237	COG4775	Outer membrane protein assembly factor BamA	766
649913231	255	25.17	27	173	50	196	1.0e-11	63.8	COG2823	Osmotically-inducible protein OsmY, contains BON domain	196
649913232	288	34.72	1	285	3	289	3.0e-33	135	COG0382	4-hydroxybenzoate polyprenyltransferase	289
649913234	119	38.18	1	55	3	57	3.0e-03	33.7	COG3237	Uncharacterized conserved protein YjbJ, UPF0337 family	67
649913236	273	36.59	1	273	3	275	1.0e-68	253	COG0077	Prephenate dehydratase	279
649913237	818	52.84	27	797	10	774	0.0e+00	982	COG0466	ATP-dependent Lon protease, bacterial type	782
649913238	85	35.71	2	80	1	84	1.0e-08	51.5	COG1977	Molybdopterin converting factor, small subunit	84
649913239	148	44.93	1	137	4	141	2.0e-36	144	COG0314	Molybdopterin synthase catalytic subunit	149
649913241	290	45.04	8	263	3	255	5.0e-60	224	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
649913244	245	28.69	3	244	5	241	3.0e-28	118	COG1381	Recombinational DNA repair protein (RecF pathway)	251
649913245	311	26.11	1	310	2	300	2.0e-34	140	COG1597	Diacylglycerol kinase family enzyme	301
649913246	595	41.29	15	592	2	587	0.0e+00	541	COG4805	Uncharacterized conserved protein, DUF885 familyt	588
649913249	357	33.7	1	356	1	286	9.0e-64	237	COG0812	UDP-N-acetylenolpyruvoylglucosamine reductase	291
649913251	222	43.13	1	211	4	214	1.0e-45	176	COG4149	ABC-type molybdate transport system, permease component	225
649913252	263	25.86	1	263	4	258	2.0e-36	146	COG0725	ABC-type molybdate transport system, periplasmic component	258
649913253	456	41.5	77	431	52	401	7.0e-87	314	COG0498	Threonine synthase	411
649913254	301	36.12	5	301	4	296	9.0e-57	213	COG0083	Homoserine kinase	299
649913255	278	56.09	5	273	18	287	1.0e-74	273	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
649913256	264	23.27	20	254	10	244	2.0e-12	66.4	COG1922	UDP-N-acetyl-D-mannosaminuronic acid transferase, WecB/TagA/CpsF family	253
649913260	488	24.84	196	475	27	313	1.0e-29	124	COG3469	Chitinase	332
649913265	307	32.67	14	284	10	305	1.0e-59	223	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
649913266	130	31.58	1	113	1	111	2.0e-10	58.2	COG0789	DNA-binding transcriptional regulator, MerR family	124
649913268	545	36.36	35	542	6	536	2.0e-103	370	COG2303	Choline dehydrogenase or related flavoprotein	542
649913269	418	31.62	18	383	9	371	2.0e-33	137	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
649913270	1066	44.2	2	1041	1	1008	0.0e+00	961	COG0841	Multidrug efflux pump subunit AcrB	1009
649913271	462	31.92	13	459	1	444	2.0e-63	236	COG1538	Outer membrane protein TolC	457
649913273	251	25	10	207	11	209	3.0e-23	102	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
649913274	342	50.29	1	341	2	339	4.0e-108	384	COG1064	D-arabinose 1-dehydrogenase, Zn-dependent alcohol dehydrogenase family	339
649913278	183	25	17	165	9	162	4.0e-16	77.9	COG0723	Rieske Fe-S protein	177
649913279	488	33.81	14	363	2	348	7.0e-58	218	COG1290	Cytochrome b subunit of the bc complex	381
649913280	460	42.73	3	453	16	467	1.0e-120	426	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
649913282	224	43.6	22	224	1	211	3.0e-46	178	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
649913284	273	25.44	1	273	1	281	2.0e-29	122	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
649913288	216	28	8	205	11	209	4.0e-23	101	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
649913289	508	22.67	25	486	10	480	2.0e-19	91.3	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
649913290	219	32.41	72	214	5	145	1.0e-19	90.1	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
649913292	370	42.48	1	369	2	374	1.0e-98	353	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
649913294	561	28.97	182	539	10	360	8.0e-65	241	COG0337	3-dehydroquinate synthetase	360
649913295	335	27.65	1	306	5	286	2.0e-22	100	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
649913296	415	20.33	1	390	4	420	2.0e-24	107	COG1486	Alpha-galactosidase/6-phospho-beta-glucosidase, family 4 of glycosyl hydrolase	442
649913297	318	26.53	1	317	1	341	2.0e-33	136	COG0673	Predicted dehydrogenase	342
649913299	413	26.41	4	398	1	379	1.0e-25	111	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649913300	304	31.75	2	293	3	312	4.0e-48	185	COG1087	UDP-glucose 4-epimerase	329
649913301	329	26.41	1	329	1	311	4.0e-34	138	COG0451	Nucleoside-diphosphate-sugar epimerase	314
649913303	210	41.23	8	210	1	211	4.0e-47	181	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
649913306	131	33.07	1	125	6	131	6.0e-18	83.3	COG1917	Cupin domain protein related to quercetin dioxygenase	131
649913307	495	26.1	31	455	2	443	4.0e-48	186	COG3119	Arylsulfatase A or related enzyme	475
649913308	275	20.25	31	267	73	298	1.0e-07	50.5	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
649913309	318	34.65	33	318	46	313	5.0e-46	178	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
649913310	606	23.08	317	594	26	279	2.0e-14	74.9	COG0668	Small-conductance mechanosensitive channel	316
649913311	193	55.44	1	193	3	190	8.0e-75	273	COG0512	Anthranilate/para-aminobenzoate synthase component II	191
649913313	186	36.15	1	130	2	131	2.0e-27	115	COG0231	Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)	131
649913314	301	23.91	1	294	2	280	3.0e-19	89.4	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
649913315	94	42.86	1	84	3	86	4.0e-18	83	COG1254	Acylphosphatase	92
649913316	179	51.74	10	179	8	179	3.0e-45	174	COG0503	Adenine/guanine phosphoribosyltransferase or related PRPP-binding protein	179
649913317	347	39.26	1	346	1	339	1.0e-105	376	COG1064	D-arabinose 1-dehydrogenase, Zn-dependent alcohol dehydrogenase family	339
649913322	504	43.15	60	504	3	440	1.0e-114	406	COG1570	Exonuclease VII, large subunit	440
649913323	447	42.21	1	447	6	463	2.0e-93	336	COG1109	Phosphomannomutase	464
649913324	127	47.31	5	97	6	98	4.0e-20	90.4	COG1188	Ribosomal 50S subunit-recycling heat shock protein, contains S4 domain	100
649913326	139	37.84	28	137	6	112	7.0e-20	89.9	COG1416	Intracellular sulfur oxidation protein, DsrE/DsrF family	112
649913327	372	24.73	71	329	46	311	2.0e-19	90.2	COG4833	Predicted alpha-1,6-mannanase, GH76 family	377
649913328	401	46.47	213	381	12	180	2.0e-38	153	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
649913330	934	48.57	398	934	37	593	0.0e+00	584	COG0749	DNA polymerase I - 3'-5' exonuclease and polymerase domains	593
649913332	356	53.78	1	355	1	342	0.0e+00	464	COG0809	S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase)	348
649913333	218	32.2	12	215	9	210	9.0e-36	143	COG2121	Uncharacterized conserved protein, lysophospholipid acyltransferase (LPLAT) superfamily	214
649913335	874	18.01	487	873	1	418	4.0e-16	81	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
649913336	119	36	10	109	2	101	3.0e-14	70.6	COG1695	DNA-binding transcriptional regulator, PadR family	138
649913337	427	51.58	16	426	1	411	0.0e+00	498	COG0334	Glutamate dehydrogenase/leucine dehydrogenase	411
649913340	214	34.85	1	195	12	192	3.0e-23	101	COG0558	Phosphatidylglycerophosphate synthase	192
649913342	228	42.33	32	220	14	198	2.0e-33	136	COG2860	Uncharacterized membrane protein YeiH	209
649913344	201	20.66	61	177	14	121	2.0e-04	39.2	COG2010	Cytochrome c, mono- and diheme variants	150
649913346	464	51.3	1	460	2	463	0.0e+00	587	COG1027	Aspartate ammonia-lyase	471
649913347	140	34.41	41	133	39	131	8.0e-12	63	COG5485	Predicted ester cyclase	131
649913348	507	47.21	1	302	2	297	1.0e-99	357	COG1951	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain	297
649913348	507	52.97	313	497	1	183	1.0e-66	247	COG1838	Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain	184
649913349	207	25	18	201	5	206	3.0e-14	71.9	COG0778	Nitroreductase	207
649913350	336	28.7	6	324	3	295	1.0e-36	147	COG0492	Thioredoxin reductase	305
649913352	277	20.6	42	274	54	282	1.0e-03	37.2	COG0842	ABC-type multidrug transport system, permease component	286
649913353	323	38.44	14	319	4	293	2.0e-73	269	COG1131	ABC-type multidrug transport system, ATPase component	293
649913354	403	27.81	28	399	8	366	8.0e-28	118	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
649913355	1089	28.93	2	1068	1	1008	0.0e+00	640	COG0841	Multidrug efflux pump subunit AcrB	1009
649913357	307	31.82	1	238	4	243	4.0e-27	115	COG2971	BadF-type ATPase, related to human N-acetylglucosamine kinase	301
649913358	771	35.58	4	771	1	760	0.0e+00	611	COG3537	Putative alpha-1,2-mannosidase	768
649913359	323	54.22	7	314	1	291	5.0e-117	414	COG0752	Glycyl-tRNA synthetase, alpha subunit	298
649913360	697	41.28	1	695	3	691	0.0e+00	641	COG0751	Glycyl-tRNA synthetase, beta subunit	691
649913364	241	60.08	1	241	2	243	7.0e-99	353	COG1137	ABC-type lipopolysaccharide export system, ATPase component	243
649913365	514	33.53	3	512	1	442	1.0e-86	314	COG1508	DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog	444
649913366	120	21.28	1	92	1	93	3.0e-04	37.5	COG1544	Ribosome-associated translation inhibitor RaiA	110
649913367	344	50.53	58	337	2	285	7.0e-94	337	COG1660	RNase adaptor protein for sRNA GlmZ degradation, contains a P-loop ATPase domain	286
649913368	621	38.81	1	603	1	565	2.0e-126	446	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
649913369	300	37.92	5	300	2	290	4.0e-58	218	COG1561	Uncharacterized conserved protein YicC, UPF0701 family	290
649913370	221	53.23	3	188	4	184	3.0e-59	221	COG0194	Guanylate kinase	191
649913372	319	44.1	131	312	3	196	3.0e-39	155	COG1573	Uracil-DNA glycosylase	202
649913373	832	37.47	4	831	3	730	0.0e+00	646	COG1198	Primosomal protein N' (replication factor Y) - superfamily II helicase	730
649913374	89	45.88	1	85	2	86	1.0e-20	91	COG0776	Bacterial nucleoid DNA-binding protein	94
649913375	183	38.83	2	183	1	181	6.0e-55	207	COG0717	Deoxycytidine triphosphate deaminase	183
649913376	236	31.25	29	227	2	209	8.0e-25	107	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
649913377	234	37.96	9	221	6	217	8.0e-40	157	COG2930	Lipid-binding SYLF domain	227
649913378	307	35.05	1	307	6	307	2.0e-57	216	COG1560	Lauroyl/myristoyl acyltransferase	308
649913379	306	41.67	4	306	6	324	2.0e-61	229	COG1044	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase	338
649913382	625	38.94	9	293	12	311	1.0e-66	248	COG0646	Methionine synthase I (cobalamin-dependent), methyltransferase domain	311
649913383	73	50	1	62	9	70	4.0e-08	49.6	COG1722	Exonuclease VII small subunit	81
649913386	329	38.08	13	328	4	321	3.0e-70	258	COG0142	Geranylgeranyl pyrophosphate synthase	322
649913387	166	53.05	1	164	1	164	4.0e-42	163	COG1666	Uncharacterized conserved protein YajQ, UPF0234 family	165
649913388	285	40.43	1	275	2	254	7.0e-69	253	COG0084	Tat protein secretion system quality control protein TatD (DNase activity)	256
649913390	709	39.03	5	559	4	553	0.0e+00	537	COG0143	Methionyl-tRNA synthetase	558
649913392	463	22.6	35	463	17	428	4.0e-52	199	COG5520	O-Glycosyl hydrolase	433
649913393	420	37.12	24	416	1	347	2.0e-89	323	COG0820	Adenine C2-methylase RlmN of 23S rRNA A2503 and tRNA A37	349
649913394	446	20.98	21	425	27	433	2.0e-18	87.6	COG2271	Sugar phosphate permease	448
649913395	326	30.49	3	324	1	312	8.0e-38	151	COG0451	Nucleoside-diphosphate-sugar epimerase	314
649913396	306	34.3	1	300	4	305	1.0e-50	193	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
649913398	479	50.32	11	473	5	460	0.0e+00	547	COG1207	Bifunctional protein GlmU, N-acetylglucosamine-1-phosphate-uridyltransferase/glucosamine-1-phosphate-acetyltransferase	460
649913400	717	47.5	5	697	3	695	0.0e+00	767	COG0855	Polyphosphate kinase	696
649913402	309	23.1	28	294	34	307	3.0e-16	79.6	COG1612	Heme A synthase	323
649913403	287	44.7	22	285	3	264	4.0e-66	245	COG0345	Pyrroline-5-carboxylate reductase	266
649913405	426	58.87	1	421	1	420	0.0e+00	577	COG0766	UDP-N-acetylglucosamine enolpyruvyl transferase	421
649913407	325	46.78	26	320	1	295	3.0e-87	315	COG2103	N-acetylmuramic acid 6-phosphate (MurNAc-6-P) etherase	298
649913408	339	27.44	7	316	23	327	5.0e-25	108	COG2367	Beta-lactamase class A	329
649913410	251	46.18	1	248	1	245	6.0e-74	270	COG0149	Triosephosphate isomerase	251
649913411	406	57.95	1	405	2	394	0.0e+00	521	COG0126	3-phosphoglycerate kinase	395
649913412	124	34.62	1	124	1	129	2.0e-17	81.1	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
649913413	335	63.14	2	330	1	330	1.0e-127	449	COG0057	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase	335
649913414	258	34.29	92	226	4	142	2.0e-17	83.1	COG4639	Predicted kinase	168
649913416	215	50.95	1	210	13	219	4.0e-48	184	COG1174	ABC-type proline/glycine betaine transport system, permease component	221
649913417	288	39.46	1	286	7	300	3.0e-74	271	COG1732	Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)	300
649913418	170	36.09	10	142	5	134	7.0e-29	120	COG3871	General stress protein 26 (function unknown)	145
649913419	190	30.81	10	184	26	208	1.0e-29	122	COG3295	Uncharacterized protein	213
649913420	529	31.37	57	355	40	334	1.0e-39	158	COG1477	Thiamine biosynthesis lipoprotein ApbE	337
649913421	273	19.65	81	249	15	149	3.0e-05	42.5	COG5126	Ca2+-binding protein, EF-hand superfamily	160
649913422	218	25.35	1	212	1	208	1.0e-22	100	COG2834	Outer membrane lipoprotein-sorting protein	211
649913424	305	31.87	12	168	14	172	5.0e-18	85.1	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
649913426	236	48.74	1	236	3	240	3.0e-83	301	COG1054	Predicted sulfurtransferase	308
649913428	883	19.28	98	480	4	418	3.0e-14	74.8	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
649913429	335	21.45	50	335	1	282	5.0e-23	102	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
649913430	126	29.46	14	125	8	119	3.0e-14	71.1	COG3682	Predicted transcriptional regulator	123
649913436	343	22.06	19	273	19	276	8.0e-13	68.5	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
649913437	761	62.01	428	756	2	328	7.0e-124	438	COG0620	Methionine synthase II (cobalamin-independent)	330
649913441	540	27.2	59	388	11	340	8.0e-29	122	COG1921	Seryl-tRNA(Sec) selenium transferase	395
649913445	549	47.74	30	531	10	517	0.0e+00	476	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
649913446	286	27.35	168	283	2	118	2.0e-14	73.4	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
649913447	442	39.24	22	437	16	438	4.0e-91	328	COG0612	Predicted Zn-dependent peptidase	438
649913448	188	26.2	1	179	1	186	4.0e-20	91.6	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
649913449	351	39.49	5	311	7	297	2.0e-70	259	COG0391	Archaeal 2-phospho-L-lactate transferase/Bacterial gluconeogenesis factor, CofD/UPF0052 family	323
649913452	498	49.16	19	492	8	465	0.0e+00	475	COG2870	ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase	467
649913455	836	25.4	586	820	2	253	1.0e-24	109	COG1192	Cellulose biosynthesis protein BcsQ	259
649913456	1504	26.16	108	509	10	387	3.0e-49	191	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
649913457	386	33.97	14	375	10	350	7.0e-57	214	COG3405	Endo-1,4-beta-D-glucanase Y	360
649913459	1777	16.95	278	511	13	232	2.0e-05	46.1	COG5010	Flp pilus assembly protein TadD, contains TPR repeats	257
649913463	350	19.81	16	323	23	310	4.0e-05	42.7	COG0392	Uncharacterized membrane protein YbhN, UPF0104 family	322
649913464	661	26.88	21	661	20	577	5.0e-92	332	COG0018	Arginyl-tRNA synthetase	577
649913465	519	41.98	8	512	1	480	0.0e+00	470	COG0260	Leucyl aminopeptidase	485
649913466	176	53.79	31	175	9	153	1.0e-49	189	COG0691	tmRNA-binding protein	153
649913468	156	18.67	9	156	4	149	2.0e-09	55.1	COG2165	Type II secretory pathway, pseudopilin PulG	149
649913469	134	31.06	3	132	2	130	5.0e-11	60.1	COG2165	Type II secretory pathway, pseudopilin PulG	149
649913473	257	34.82	10	242	2	246	1.0e-46	179	COG3375	Predicted acetyltransferase, GNAT superfamily	266
649913474	373	26.19	1	366	1	372	3.0e-51	196	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
649913478	793	18.07	32	515	21	459	5.0e-19	90.2	COG0531	Amino acid transporter	466
649913480	538	30.94	1	526	4	513	4.0e-78	286	COG0815	Apolipoprotein N-acyltransferase	518
649913481	375	61.76	124	361	1	238	2.0e-93	336	COG1186	Protein chain release factor B	239
649913483	135	52.42	10	131	13	136	2.0e-40	158	COG1832	Predicted CoA-binding protein	140
649913485	708	31.1	287	707	139	568	1.0e-76	281	COG4232	Thiol:disulfide interchange protein	569
649913488	445	56.71	21	445	12	434	0.0e+00	560	COG2256	Replication-associated recombination protein RarA (DNA-dependent ATPase)	436
649913489	264	36.12	12	262	1	258	1.0e-43	170	COG0566	tRNA G18 (ribose-2'-O)-methylase SpoU	260
649913490	214	42.25	3	214	1	210	9.0e-48	183	COG0009	tRNA A37 threonylcarbamoyladenosine synthetase subunit TsaC/SUA5/YrdC	211
649913491	223	22.71	17	219	28	223	7.0e-11	61	COG1434	Uncharacterized SAM-binding protein YcdF, DUF218 family	223
649913494	189	33.33	19	189	1	176	8.0e-25	107	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
649913495	266	50.61	6	252	4	241	7.0e-72	263	COG1189	Predicted rRNA methylase YqxC, contains S4 and FtsJ domains	245
649913496	285	40.64	3	283	2	280	7.0e-65	240	COG0061	NAD kinase	281
649913497	115	32.41	3	110	1	107	1.0e-13	68.7	COG1695	DNA-binding transcriptional regulator, PadR family	138
649913498	892	19.03	498	892	2	419	1.0e-13	72.9	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
649913499	320	18.18	5	305	19	308	3.0e-07	49.6	COG2017	Galactose mutarotase or related enzyme	308
649913500	452	19.05	52	426	2	335	9.0e-17	81.8	COG0673	Predicted dehydrogenase	342
649913503	267	45.28	15	267	1	252	5.0e-66	244	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
649913504	313	34.73	3	306	1	310	3.0e-44	172	COG0524	Sugar or nucleoside kinase, ribokinase family	311
649913506	426	58.17	9	421	7	422	0.0e+00	541	COG4573	Tagatose-1,6-bisphosphate aldolase non-catalytic subunit AgaZ/GatZ	426
649913507	352	20.46	50	349	52	289	1.0e-10	60.8	COG2159	Predicted metal-dependent hydrolase, TIM-barrel fold	293
649913509	151	62.24	3	145	2	140	1.0e-57	215	COG0229	Peptide methionine sulfoxide reductase MsrB	140
649913510	172	44.77	2	167	3	174	8.0e-61	226	COG0225	Peptide methionine sulfoxide reductase MsrA	174
649913511	114	32.65	7	104	4	100	2.0e-11	61.4	COG1695	DNA-binding transcriptional regulator, PadR family	138
649913512	903	19.54	635	903	119	419	2.0e-12	68.6	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
649913513	241	53.85	15	230	1	221	3.0e-75	275	COG1136	ABC-type lipoprotein export system, ATPase component	226
649913514	360	20.71	6	360	14	408	4.0e-19	89.2	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
649913515	409	20.85	1	406	1	406	2.0e-19	90.7	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
649913519	863	13.19	61	689	6	660	9.0e-08	53	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
649913520	160	42.54	8	141	2	132	2.0e-27	115	COG1321	Mn-dependent transcriptional regulator, DtxR family	154
649913522	389	40.1	1	381	2	386	1.0e-96	347	COG0153	Galactokinase	390
649913523	349	43.86	9	349	2	337	2.0e-93	336	COG1085	Galactose-1-phosphate uridylyltransferase	338
649913526	488	46.85	13	484	6	458	0.0e+00	492	COG1139	L-lactate utilization protein LutB, contains a ferredoxin-type domain	459
649913527	212	27.23	2	212	1	216	5.0e-23	101	COG1556	L-lactate utilization protein LutC, contains LUD domain	218
649913530	71	47.76	5	71	2	68	6.0e-16	75.6	COG1476	DNA-binding transcriptional regulator, XRE-family HTH domain	68
649913531	400	40.84	5	395	26	426	5.0e-107	381	COG4952	L-rhamnose isomerase	430
649913532	362	29.39	71	359	28	312	7.0e-24	104	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
649913533	731	37.81	7	452	1	404	2.0e-103	370	COG3347	Rhamnose utilisation protein RhaD, predicted bifunctional aldolase and dehydrogenase	404
649913534	485	24.74	25	481	2	468	8.0e-47	181	COG1070	Sugar (pentulose or hexulose) kinase	502
649913535	362	23.74	12	341	1	314	3.0e-30	126	COG0451	Nucleoside-diphosphate-sugar epimerase	314
649913538	447	31.67	36	436	6	372	6.0e-92	331	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
649913540	237	26.42	8	232	9	251	1.0e-17	83.4	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
649913541	358	29.89	5	347	4	355	2.0e-58	219	COG0337	3-dehydroquinate synthetase	360
649913542	601	31.97	8	562	1	542	2.0e-90	327	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
649913543	347	31.08	28	342	2	308	3.0e-39	155	COG0451	Nucleoside-diphosphate-sugar epimerase	314
649913544	311	21.28	1	292	2	291	4.0e-18	85.6	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
649913545	153	21.05	9	140	14	136	3.0e-04	38.4	COG2246	Putative flippase GtrA (transmembrane translocase of bactoprenol-linked glucose)	139
649913546	306	25.21	61	286	69	300	2.0e-18	86.9	COG0657	Acetyl esterase/lipase	312
649913547	409	39.23	1	409	3	408	3.0e-83	302	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
649913550	284	34.41	7	278	33	293	4.0e-38	151	COG0501	Zn-dependent protease with chaperone function	302
649913553	156	23.6	1	152	1	148	2.0e-06	45.7	COG3088	Cytochrome c-type biogenesis protein CcmH/NrfF	153
649913554	700	33.99	14	672	1	636	7.0e-114	405	COG1138	Cytochrome c biogenesis factor	648
649913556	602	21.21	4	560	2	490	1.0e-33	138	COG0591	Na+/proline symporter	493
649913558	818	30.3	9	289	2	285	3.0e-38	154	COG0515	Serine/threonine protein kinase	384
649913560	193	30.95	18	185	16	178	2.0e-22	99	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
649913563	429	67.37	1	426	1	420	0.0e+00	659	COG0148	Enolase	423
649913564	537	48.96	2	532	1	506	0.0e+00	619	COG0696	Phosphoglycerate mutase (BPG-independent, AlkP superfamily)	509
649913565	118	29.51	1	117	6	127	2.0e-16	77.6	COG3324	Predicted enzyme related to lactoylglutathione lyase	127
649913566	199	50	2	199	1	198	7.0e-64	236	COG0353	Recombinational DNA repair protein RecR	198
649913567	109	42.86	9	103	7	101	6.0e-16	75.6	COG0718	Conserved DNA-binding protein YbaB (function unknown)	105
649913568	763	38.49	78	530	1	448	1.0e-101	364	COG2812	DNA polymerase III, gamma/tau subunits	515
649913574	106	45.9	42	99	4	64	2.0e-12	64.1	COG1983	Phage shock protein PspC (stress-responsive transcriptional regulator)	70
649913575	437	48.88	19	414	3	394	4.0e-109	388	COG0019	Diaminopimelate decarboxylase	394
649913577	246	57.68	1	241	1	241	1.0e-92	332	COG0217	Transcriptional and/or translational regulatory protein YebC/TACO1	241
649913579	307	45.27	8	300	4	297	1.0e-78	286	COG3643	Glutamate formiminotransferase	302
649913581	359	35.21	1	337	1	313	3.0e-60	225	COG2826	Transposase and inactivated derivatives, IS30 family	318
649913583	208	42.93	15	198	1	177	1.0e-30	126	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
649913584	793	31.65	560	791	54	289	2.0e-20	94.8	COG0741	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)	296
649913585	418	27.12	18	418	1	419	8.0e-32	131	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
649913586	419	27.49	18	419	1	419	4.0e-35	142	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
649913590	449	35.95	57	445	33	421	3.0e-72	265	COG2379	Glycerate-2-kinase	422
649913595	304	45.1	2	287	1	286	2.0e-73	269	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
649913596	550	39.56	13	550	1	521	2.0e-100	360	COG1620	L-lactate permease	522
649913597	251	35.44	17	248	1	237	2.0e-44	172	COG2186	DNA-binding transcriptional regulator, FadR family	241
649913599	225	41.92	1	224	1	227	3.0e-51	194	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
649913600	476	30.58	142	466	17	333	1.0e-37	151	COG0642	Signal transduction histidine kinase	336
649913602	902	13.77	104	864	28	760	4.0e-12	67.6	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
649913604	435	28.3	1	423	2	405	3.0e-47	182	COG1819	UDP:flavonoid glycosyltransferase YjiC, YdhE family	406
649913605	229	33.81	6	213	3	210	4.0e-39	154	COG2258	Uncharacterized conserved protein YiiM, contains MOSC domain	210
649913610	358	27.86	8	344	1	330	1.0e-35	144	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
649913612	469	19.64	12	454	1	382	1.0e-10	61.4	COG2814	Predicted arabinose efflux permease, MFS family	394
649913614	775	21.62	32	705	5	683	3.0e-62	234	COG3250	Beta-galactosidase/beta-glucuronidase	808
649913618	255	39.34	1	242	1	230	2.0e-41	162	COG3279	DNA-binding response regulator, LytR/AlgR family	244
649913622	638	27.2	8	630	1	542	1.0e-67	251	COG2303	Choline dehydrogenase or related flavoprotein	542
649913626	194	45.56	14	193	1	170	3.0e-48	185	COG1778	 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsC and related HAD superfamily phosphatases	170
649913631	112	47.57	8	110	2	103	3.0e-23	100	COG4357	Uncharacterized protein, contains Zn-finger domain of CHY type	105
649913632	209	49.61	82	209	2	130	1.0e-51	196	COG0229	Peptide methionine sulfoxide reductase MsrB	140
649913633	576	28.77	1	212	10	217	3.0e-26	113	COG0785	Cytochrome c biogenesis protein CcdA	220
649913634	503	27.5	36	478	1	443	3.0e-53	203	COG3119	Arylsulfatase A or related enzyme	475
649913636	471	31.33	38	443	3	442	4.0e-56	212	COG3119	Arylsulfatase A or related enzyme	475
649913640	345	39.14	38	339	13	298	3.0e-65	242	COG2421	Acetamidase/formamidase	305
649913644	259	36.36	3	246	2	239	7.0e-34	137	COG3279	DNA-binding response regulator, LytR/AlgR family	244
649913645	167	34.18	1	151	3	156	1.0e-31	129	COG1956	GAF domain-containing protein, putative methionine-R-sulfoxide reductase	163
649913647	347	17.87	80	265	18	217	1.0e-06	47.9	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
649913649	295	34.36	34	282	2	258	2.0e-46	179	COG3622	Hydroxypyruvate isomerase	260
649913650	480	26.73	27	369	1	417	4.0e-38	152	COG3119	Arylsulfatase A or related enzyme	475
649913651	227	36.36	7	221	5	223	1.0e-30	126	COG1802	DNA-binding transcriptional regulator, GntR family	230
649913653	650	25.3	80	649	63	618	8.0e-69	255	COG1506	Dipeptidyl aminopeptidase/acylaminoacyl peptidase	620
649913654	551	23.2	194	546	73	427	8.0e-23	102	COG2234	Zn-dependent amino- or carboxypeptidase, M28 family	435
649913655	334	20.25	12	331	24	316	2.0e-16	80	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
649913656	349	30.91	33	344	16	326	1.0e-46	180	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
649913665	155	22.41	9	124	10	123	1.0e-09	56.4	COG1917	Cupin domain protein related to quercetin dioxygenase	131
649913680	266	33.33	46	156	15	122	1.0e-09	56.9	COG1846	DNA-binding transcriptional regulator, MarR family	126
649913681	315	25	8	312	5	282	8.0e-19	87.8	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
649913682	339	19.03	9	336	1	281	4.0e-16	79	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
649913683	150	23.19	16	146	1	138	7.0e-08	50.2	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
649913687	97	30.43	1	87	1	92	3.0e-11	59.9	COG2350	Uncharacterized conserved protein YciI, contains a putative active-site phosphohistidine	92
649913688	146	24	19	141	1	125	8.0e-08	49.9	COG1846	DNA-binding transcriptional regulator, MarR family	126
649913689	165	21.74	13	150	16	125	6.0e-05	40.7	COG3439	Uncharacterized conserved protein, DUF302 family	137
649913691	334	38.02	1	330	1	325	2.0e-62	232	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
649913692	371	24.54	27	366	3	368	6.0e-41	161	COG2021	Homoserine acetyltransferase	368
649913694	1167	24.24	43	908	196	942	3.0e-65	244	COG0383	Alpha-mannosidase	943
649913696	713	30	13	152	12	145	2.0e-17	84.6	COG3710	DNA-binding winged helix-turn-helix (wHTH) domain	148
649913697	763	31.29	61	762	28	737	4.0e-130	459	COG3537	Putative alpha-1,2-mannosidase	768
649913698	347	40.94	6	342	2	340	1.0e-103	369	COG2008	Threonine aldolase	342
649913699	479	20.58	39	471	13	430	3.0e-19	90.1	COG3669	Alpha-L-fucosidase	430
649913701	518	42.9	65	401	36	340	3.0e-59	223	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
649913703	137	25	8	127	3	122	3.0e-14	70.7	COG3682	Predicted transcriptional regulator	123
649913705	957	47.04	673	957	9	293	5.0e-85	309	COG3285	Eukaryotic-type DNA primase	299
649913706	310	39.15	1	280	2	276	1.0e-63	236	COG1273	Non-homologous end joining protein Ku, dsDNA break repair	278
649913707	147	33.65	33	136	17	120	2.0e-08	52.2	COG1846	DNA-binding transcriptional regulator, MarR family	126
649913708	131	30.09	20	125	16	124	3.0e-08	51.1	COG3324	Predicted enzyme related to lactoylglutathione lyase	127
649913710	316	37.27	1	316	1	312	5.0e-70	257	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
649913711	536	48.07	2	531	12	545	0.0e+00	564	COG2225	Malate synthase	545
649913712	257	23.97	6	257	3	262	1.0e-26	113	COG3971	2-keto-4-pentenoate hydratase	264
649913713	321	36.52	15	292	2	269	3.0e-58	219	COG2041	Periplasmic DMSO/TMAO reductase YedYZ, molybdopterin-dependent catalytic subunit	271
649913714	232	37.83	3	232	5	208	1.0e-30	126	COG2717	Periplasmic DMSO/TMAO reductase YedYZ, heme-binding membrane subunit	209
649913716	228	30.98	44	227	4	154	2.0e-26	113	COG1225	Peroxiredoxin	157
649913717	460	52.39	1	460	1	451	0.0e+00	558	COG0541	Signal recognition particle GTPase	451
649913719	204	38.27	6	195	8	193	1.0e-41	162	COG0218	GTP-binding protein EngB required for normal cell division	200
649913721	249	25.12	23	232	2	209	1.0e-32	133	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
649913722	197	44.68	13	197	5	191	3.0e-41	161	COG2353	Polyisoprenoid-binding periplasmic protein YceI	192
649913723	415	22.77	33	411	28	394	3.0e-19	89.9	COG2814	Predicted arabinose efflux permease, MFS family	394
649913724	570	35.25	19	538	8	499	3.0e-108	386	COG0155	Sulfite reductase, beta subunit (hemoprotein)	510
649913725	210	41.49	1	188	1	188	7.0e-44	170	COG1648	Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain)	210
649913726	258	44.07	1	233	2	233	7.0e-53	200	COG0007	Uroporphyrinogen-III methylase (siroheme synthase)	244
649913727	210	29.55	20	195	12	181	7.0e-16	77.4	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
649913729	1355	34.45	942	1348	16	409	2.0e-70	261	COG3876	Uncharacterized conserved protein YbbC, DUF1343 family	409
649913730	380	41.21	3	379	2	377	1.0e-91	330	COG1820	N-acetylglucosamine-6-phosphate deacetylase	380
649913733	461	44.11	2	461	3	461	0.0e+00	561	COG1904	Glucuronate isomerase	463
649913734	163	49.69	6	163	1	159	5.0e-48	183	COG3265	Gluconate kinase	161
649913735	258	39.76	6	252	1	251	6.0e-44	171	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
649913736	246	55.2	6	246	3	252	2.0e-68	252	COG1691	NCAIR mutase (PurE)-related protein	254
649913737	150	38.18	46	148	18	126	2.0e-16	78.8	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
649913738	317	37.45	42	308	1	264	9.0e-61	227	COG1606	ATP-utilizing enzyme, PP-loop superfamily	269
649913739	276	43.53	28	274	1	251	6.0e-44	171	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
649913741	392	28.75	83	385	35	357	2.0e-42	166	COG4225	Rhamnogalacturonyl hydrolase YesR	357
649913742	276	50	1	276	1	278	1.0e-97	349	COG3717	5-keto 4-deoxyuronate isomerase	278
649913743	361	25.43	15	356	1	311	5.0e-24	105	COG0524	Sugar or nucleoside kinase, ribokinase family	311
649913744	222	45.24	8	217	2	211	2.0e-56	211	COG0800	2-keto-3-deoxy-6-phosphogluconate aldolase	211
649913746	627	33.11	9	396	15	452	8.0e-96	345	COG0147	Anthranilate/para-aminobenzoate synthases component I	462
649913747	1092	30.88	256	1085	200	939	1.0e-123	438	COG0383	Alpha-mannosidase	943
649913751	380	27.53	46	344	3	309	4.0e-34	139	COG2706	6-phosphogluconolactonase, cycloisomerase 2 family	346
649913752	520	18.02	9	519	13	459	2.0e-20	94.2	COG0277	FAD/FMN-containing dehydrogenase	459
649913753	388	38.53	36	388	5	345	3.0e-72	265	COG2706	6-phosphogluconolactonase, cycloisomerase 2 family	346
649913754	336	24.6	1	241	5	245	2.0e-12	67	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
649913756	627	20.26	178	627	3	501	1.0e-30	128	COG3534	Alpha-L-arabinofuranosidase	501
649913757	228	36.84	1	227	4	218	2.0e-51	195	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
649913758	531	29.98	1	520	2	542	9.0e-91	328	COG1069	Ribulose kinase	544
649913760	633	20.53	45	606	4	595	2.0e-48	187	COG1874	Beta-galactosidase GanA	673
649913763	400	27.1	90	388	36	352	4.0e-42	165	COG4225	Rhamnogalacturonyl hydrolase YesR	357
649913764	294	19.49	47	277	6	216	9.0e-12	64.6	COG2755	Lysophospholipase L1 or related esterase	216
649913766	444	20.63	187	402	3	211	7.0e-15	75.3	COG2755	Lysophospholipase L1 or related esterase	216
649913775	460	23.88	41	458	43	445	2.0e-27	117	COG1538	Outer membrane protein TolC	457
649913777	381	35.07	11	373	16	343	2.0e-53	203	COG1566	Multidrug resistance efflux pump	352
649913778	144	31.08	1	144	4	151	3.0e-06	44.2	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
649913780	597	35.2	142	265	27	149	2.0e-21	97.6	COG5616	TolB amino-terminal domain (function unknown)	152
649913781	317	30	160	298	6	140	8.0e-14	71.4	COG5616	TolB amino-terminal domain (function unknown)	152
649913782	348	33.19	35	262	18	236	5.0e-43	168	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
649913783	559	52.55	26	551	9	530	0.0e+00	528	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
649913784	198	34.07	19	197	29	207	5.0e-30	124	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
649913786	245	23.76	142	242	22	108	1.0e-03	37.3	COG2863	Cytochrome c553	121
649913787	211	23.75	26	180	10	169	3.0e-14	71.7	COG0723	Rieske Fe-S protein	177
649913788	508	32.96	16	372	8	347	1.0e-53	204	COG1290	Cytochrome b subunit of the bc complex	381
649913789	288	30.86	8	263	9	259	1.0e-26	113	COG3336	Cytochrome c oxidase assembly factor CtaG	299
649913791	1025	28.26	722	990	96	365	2.0e-31	131	COG4585	Signal transduction histidine kinase	365
649913792	208	43.6	6	208	1	211	8.0e-52	196	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
649913793	222	20.23	3	200	8	269	7.0e-14	71	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
649913795	767	30.95	49	366	2	306	9.0e-40	159	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
649913796	549	52.05	53	539	2	446	0.0e+00	518	COG0166	Glucose-6-phosphate isomerase	446
649913797	489	43.48	29	482	2	483	0.0e+00	514	COG0364	Glucose-6-phosphate 1-dehydrogenase	483
649913800	238	32.86	12	221	10	218	8.0e-28	117	COG3619	Uncharacterized membrane protein YoaK, UPF0700 family	226
649913802	367	39.78	1	356	2	337	2.0e-70	259	COG1600	Epoxyqueuosine reductase  QueG (queuosine biosynthesis)	337
649913803	331	22.74	60	330	20	296	3.0e-19	89.6	COG1295	Uncharacterized membrane protein, BrkB/YihY/UPF0761 family (not an RNase)	303
649913804	714	33.01	412	713	95	364	2.0e-41	164	COG2208	Serine phosphatase RsbU, regulator of sigma subunit	367
649913805	405	27.09	34	329	46	320	2.0e-20	93.7	COG3391	DNA-binding beta-propeller fold protein YncE	381
649913808	226	31.7	4	224	1	221	1.0e-26	112	COG2386	ABC-type transport system involved in cytochrome c biogenesis, permease component	221
649913809	159	44.08	2	153	1	152	5.0e-33	133	COG2606	Cys-tRNA(Pro) deacylase, prolyl-tRNA editing enzyme YbaK/EbsC	155
649913810	223	34.55	8	221	4	218	4.0e-47	181	COG1131	ABC-type multidrug transport system, ATPase component	293
649913811	152	25.78	11	136	12	136	2.0e-14	71.8	COG2332	Cytochrome c-type biogenesis protein CcmE	153
649913812	492	65.58	42	468	2	430	0.0e+00	678	COG0422	Thiamine biosynthesis protein ThiC	432
649913814	132	43.36	1	111	3	114	1.0e-24	105	COG1970	Large-conductance mechanosensitive channel	130
649913816	354	55.62	4	348	5	346	6.0e-123	433	COG0182	Methylthioribose-1-phosphate isomerase (methionine salvage pathway), a paralog of eIF-2B alpha subunit	346
649913819	201	36.9	4	190	1	175	6.0e-35	140	COG0461	Orotate phosphoribosyltransferase	201
649913820	307	26.67	98	290	44	216	7.0e-05	41.4	COG1266	Membrane protease YdiL, CAAX protease family	226
649913821	1012	59.79	1	925	1	931	0.0e+00	1368	COG0178	Excinuclease UvrABC ATPase subunit	935
649913825	212	26.17	1	207	1	206	1.0e-25	110	COG0778	Nitroreductase	207
649913826	328	25.26	50	314	2	282	2.0e-20	93.2	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
649913827	205	45.64	5	199	3	189	2.0e-53	202	COG0163	3-polyprenyl-4-hydroxybenzoate decarboxylase	191
649913830	431	45.21	1	431	1	438	0.0e+00	476	COG0015	Adenylosuccinate lyase	438
649913831	615	36.26	30	454	14	443	1.0e-60	227	COG0038	H+/Cl- antiporter ClcA	443
649913832	89	29.03	4	63	1	62	3.0e-08	50	COG0695	Glutaredoxin	80
649913833	258	46.64	5	251	2	250	2.0e-52	199	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
649913834	171	57.05	1	149	3	151	1.0e-47	182	COG0590	tRNA(Arg) A34 adenosine deaminase TadA	152
649913838	348	37.78	5	348	7	345	2.0e-82	299	COG2957	Agmatine/peptidylarginine deiminase	346
649913840	305	35.76	4	303	1	274	5.0e-55	208	COG0388	Predicted amidohydrolase	274
649913841	187	38.25	1	183	2	163	5.0e-41	160	COG1945	Pyruvoyl-dependent arginine decarboxylase (PvlArgDC)	163
649913842	476	31.88	37	447	2	427	8.0e-75	274	COG0174	Glutamine synthetase	443
649913843	270	36.96	12	263	1	251	2.0e-36	146	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
649913844	537	21.07	46	417	18	421	2.0e-33	137	COG3669	Alpha-L-fucosidase	430
649913847	662	65.81	1	657	3	658	0.0e+00	1036	COG0556	Excinuclease UvrABC helicase subunit UvrB	663
649913848	468	28.44	25	458	3	389	5.0e-49	188	COG2311	Uncharacterized membrane protein YeiB	394
649913849	477	17.98	8	463	9	394	1.0e-13	71.4	COG2814	Predicted arabinose efflux permease, MFS family	394
649913850	242	33.92	9	234	3	218	2.0e-30	125	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
649913852	400	26.47	1	298	9	287	3.0e-27	116	COG1566	Multidrug resistance efflux pump	352
649913853	201	40.2	1	201	2	201	4.0e-45	174	COG1974	SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase)	201
649913854	246	44.83	1	227	1	227	5.0e-50	191	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
649913856	423	40.29	12	414	1	384	1.0e-91	330	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
649913857	120	26.02	11	118	11	133	4.0e-13	66.9	COG1815	Flagellar basal body rod protein FlgB	133
649913858	152	36.84	1	152	1	137	6.0e-35	140	COG1558	Flagellar basal body rod protein FlgC	137
649913859	105	32.69	1	104	1	104	8.0e-12	62.3	COG1677	Flagellar hook-basal body complex protein FliE	105
649913860	559	30.36	19	552	5	542	9.0e-83	301	COG1766	Flagellar biosynthesis/type III secretory pathway M-ring protein FliF/YscJ	545
649913861	341	35.91	3	339	4	339	6.0e-65	241	COG1536	Flagellar motor switch protein FliG	339
649913863	434	50.81	2	431	8	438	0.0e+00	531	COG1157	Flagellar biosynthesis/type III secretory pathway ATPase	441
649913867	408	38	1	408	2	423	1.0e-64	241	COG1749	Flagellar hook protein FlgE	423
649913868	174	25.43	4	173	1	159	7.0e-12	63.7	COG1580	Flagellar basal body-associated protein FliL	159
649913871	271	51	72	271	48	247	2.0e-54	206	COG1338	Flagellar biosynthetic protein FliP	248
649913872	89	32.58	1	89	1	89	5.0e-12	62.9	COG1987	Flagellar biosynthesis protein FliQ	89
649913873	262	28.17	11	261	4	255	6.0e-26	111	COG1684	Flagellar biosynthesis protein FliR	258
649913874	373	37.22	1	348	5	355	4.0e-75	275	COG1377	Flagellar biosynthesis protein FlhB	363
649913875	696	46.66	1	696	2	694	0.0e+00	693	COG1298	Flagellar biosynthesis pathway, component FlhA	696
649913876	294	41.81	58	286	23	247	3.0e-47	182	COG1191	DNA-directed RNA polymerase specialized sigma subunit	247
649913877	326	25.42	1	292	17	315	2.0e-31	130	COG1868	Flagellar motor switch protein FliM	332
649913879	249	31.66	1	240	1	259	6.0e-34	137	COG4786	Flagellar basal body rod protein FlgG	265
649913880	262	49.44	1	262	1	265	4.0e-69	254	COG4786	Flagellar basal body rod protein FlgG	265
649913882	269	26.13	36	251	1	216	9.0e-27	114	COG2063	Flagellar basal body L-ring protein FlgH	230
649913883	371	45.82	3	371	1	365	2.0e-93	336	COG1706	Flagellar basal body P-ring protein FlgI	365
649913888	299	20.14	8	283	9	291	9.0e-13	67.8	COG1344	Flagellin and related hook-associated protein FlgL	360
649913890	406	31.32	37	380	8	339	3.0e-59	222	COG3693	Endo-1,4-beta-xylanase, GH35 family	345
649913891	443	25.89	23	435	3	398	8.0e-49	188	COG1819	UDP:flavonoid glycosyltransferase YjiC, YdhE family	406
649913892	426	28.4	1	415	1	398	6.0e-50	191	COG1819	UDP:flavonoid glycosyltransferase YjiC, YdhE family	406
649913894	88	59.09	1	88	2	89	5.0e-24	102	COG0184	Ribosomal protein S15P/S13E	89
649913895	799	54.83	1	692	3	691	0.0e+00	858	COG1185	Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase)	692
649913897	340	25.54	1	336	6	371	6.0e-19	88.7	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
649913898	249	26.91	4	246	1	236	2.0e-32	132	COG0412	Dienelactone hydrolase	236
649913899	318	37.14	3	312	1	296	3.0e-64	238	COG1090	NAD dependent epimerase/dehydratase family enzyme	297
649913900	279	36.88	18	278	5	245	1.0e-64	239	COG1127	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, ATPase component MlaF	263
649913901	259	46.15	12	258	21	267	1.0e-55	210	COG0767	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, permease component MlaE	267
649913902	361	34.1	1	333	1	339	2.0e-55	209	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
649913903	319	32.13	24	299	4	279	4.0e-43	168	COG1562	Phytoene/squalene synthetase	288
649913904	318	29.61	2	304	3	280	6.0e-41	161	COG1562	Phytoene/squalene synthetase	288
649913905	457	26.28	4	453	3	484	4.0e-40	159	COG3349	Uncharacterized conserved protein, contains NAD-binding domain and a Fe-S cluster	485
649913908	360	18.56	69	353	18	301	2.0e-14	73.4	COG0668	Small-conductance mechanosensitive channel	316
649913909	492	21.24	33	465	30	485	5.0e-32	132	COG1032	Radical SAM superfamily enzyme YgiQ, UPF0313 family	490
649913911	432	20.87	25	421	47	449	4.0e-18	86.4	COG1538	Outer membrane protein TolC	457
649913914	616	36.58	52	553	9	466	1.0e-86	314	COG0608	Single-stranded DNA-specific exonuclease, DHH superfamily, may be involved in archaeal DNA replication intiation	491
649913916	119	57.69	49	100	3	54	7.0e-16	76.1	COG3411	(2Fe-2S) ferredoxin	64
649913920	326	27.71	10	311	1	307	8.0e-34	137	COG0451	Nucleoside-diphosphate-sugar epimerase	314
649913921	242	22.73	6	220	4	211	4.0e-09	55.5	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
649913922	341	30.32	1	339	1	313	3.0e-46	179	COG0451	Nucleoside-diphosphate-sugar epimerase	314
649913924	452	43.15	16	450	3	436	0.0e+00	467	COG0621	tRNA A37 methylthiotransferase MiaB	437
649913925	165	39.87	5	156	2	151	5.0e-29	120	COG1259	Bifunctional DNase/RNase	151
649913926	434	42.24	7	434	2	427	5.0e-100	358	COG0128	5-enolpyruvylshikimate-3-phosphate synthase	428
649913927	622	31.21	342	621	86	365	8.0e-44	172	COG2208	Serine phosphatase RsbU, regulator of sigma subunit	367
649913928	251	53.1	20	244	4	228	1.0e-62	233	COG0274	Deoxyribose-phosphate aldolase	228
649913929	215	36.08	20	207	9	199	4.0e-34	137	COG1573	Uracil-DNA glycosylase	202
649913930	184	51.18	13	182	9	178	1.0e-58	218	COG0634	Hypoxanthine-guanine phosphoribosyltransferase	178
649913931	393	23.88	58	386	4	333	1.0e-24	108	COG0673	Predicted dehydrogenase	342
649913932	279	24.31	5	278	16	284	1.0e-19	90.3	COG0682	Prolipoprotein diacylglyceryltransferase	287
649913936	435	24.76	21	222	23	222	6.0e-09	55.7	COG3063	Tfp pilus assembly protein PilF	250
649913937	981	47.74	6	978	3	934	0.0e+00	1168	COG0178	Excinuclease UvrABC ATPase subunit	935
649913938	175	33.33	8	164	4	156	6.0e-29	120	COG0597	Lipoprotein signal peptidase	167
649913939	956	46.03	17	946	3	933	0.0e+00	1051	COG0060	Isoleucyl-tRNA synthetase	933
649913941	324	22.03	148	323	69	243	2.0e-07	50.1	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
649913942	203	25.99	5	169	3	170	4.0e-07	48.3	COG1437	Adenylate cyclase class IV, CYTH domain (includes archaeal enzymes of unknown function)	178
649913943	340	46.94	16	210	16	210	4.0e-56	212	COG0009	tRNA A37 threonylcarbamoyladenosine synthetase subunit TsaC/SUA5/YrdC	211
649913945	242	20.71	17	209	6	200	4.0e-15	75.3	COG1011	FMN phosphatase YigB, HAD superfamily	229
649913947	434	27.9	1	417	2	399	4.0e-44	172	COG1819	UDP:flavonoid glycosyltransferase YjiC, YdhE family	406
649913949	500	18.31	4	418	5	359	8.0e-13	68.7	COG2814	Predicted arabinose efflux permease, MFS family	394
649913950	705	15.44	80	644	63	646	3.0e-14	74.3	COG1289	Uncharacterized membrane protein YccC	674
649913951	404	26.43	2	401	6	337	1.0e-43	171	COG1566	Multidrug resistance efflux pump	352
649913953	487	25.78	71	485	44	452	4.0e-36	146	COG1538	Outer membrane protein TolC	457
649913954	207	21.5	5	205	4	217	8.0e-14	70.7	COG1011	FMN phosphatase YigB, HAD superfamily	229
649913955	391	26.23	10	382	12	390	2.0e-44	173	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
649913956	210	33.49	1	210	12	229	8.0e-30	123	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
649913957	99	46.75	5	81	2	77	4.0e-11	59.8	COG1314	Preprotein translocase subunit SecG	86
649913958	303	26.97	10	152	3	153	2.0e-10	60	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
649913962	250	43.5	2	246	4	233	8.0e-60	223	COG3910	Predicted ATPase	233
649913967	217	39.45	1	217	1	205	7.0e-45	173	COG0125	Thymidylate kinase	208
649913971	845	20.71	128	431	119	419	3.0e-16	81	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
649913974	795	14.9	1	795	7	768	1.0e-21	98.8	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
649913975	198	56.35	12	187	3	183	4.0e-65	240	COG2818	3-methyladenine DNA glycosylase Tag	188
649913977	155	54.05	8	150	4	151	1.0e-45	175	COG3865	Glyoxalase superfamily enzyme, possibly 3-demethylubiquinone-9 3-methyltransferase	151
649913982	337	42.09	1	333	4	338	2.0e-82	299	COG1044	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase	338
649913984	583	22.08	23	420	14	381	6.0e-28	119	COG0617	tRNA nucleotidyltransferase/poly(A) polymerase	412
649913986	1173	47.5	4	1135	3	1108	0.0e+00	1227	COG0587	DNA polymerase III, alpha subunit	1139
649913987	281	62.69	19	278	56	315	2.0e-104	372	COG0825	Acetyl-CoA carboxylase alpha subunit	317
649913988	338	23.77	15	232	5	224	6.0e-08	52.2	COG1266	Membrane protease YdiL, CAAX protease family	226
649913992	256	47.19	25	255	8	235	3.0e-52	198	COG0284	Orotidine-5'-phosphate decarboxylase	240
649913994	273	38.46	13	272	5	263	3.0e-63	235	COG0351	Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase	263
649913995	74	42.03	4	72	3	68	9.0e-12	61.8	COG2104	Sulfur carrier protein ThiS (thiamine biosynthesis)	68
649913998	391	26.7	26	383	6	381	5.0e-25	108	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649913999	397	25	9	397	4	379	1.0e-31	130	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649914000	224	26.46	12	195	22	205	5.0e-16	78.2	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
649914001	495	49.75	300	495	40	226	2.0e-63	237	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
649914006	392	22.06	60	389	48	381	2.0e-17	83.5	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649914007	328	19.87	15	306	6	294	2.0e-16	80.2	COG1216	Glycosyltransferase, GT2 family	305
649914011	501	18.28	22	465	18	454	4.0e-24	106	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
649914012	454	20.19	27	447	9	434	3.0e-15	77.1	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
649914013	482	19.13	48	431	9	382	5.0e-03	36.3	COG3307	O-antigen ligase	424
649914014	355	30.24	7	355	3	378	2.0e-36	146	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649914016	377	30.73	5	377	4	378	7.0e-34	138	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649914017	386	61.08	5	207	2	203	1.0e-79	290	COG0108	3,4-dihydroxy-2-butanone 4-phosphate synthase	203
649914019	241	55.88	69	237	1	152	5.0e-57	214	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
649914020	333	36.01	1	331	1	283	1.0e-60	226	COG1319	CO or xanthine dehydrogenase, FAD-binding subunit	284
649914021	746	33.91	11	746	5	728	0.0e+00	503	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
649914023	312	65.05	3	311	2	295	3.0e-114	405	COG0214	Pyridoxal biosynthesis lyase PdxS	296
649914024	197	50	7	195	1	194	1.0e-55	209	COG0311	Glutamine amidotransferase PdxT (pyridoxal biosynthesis)	194
649914025	239	23.83	12	239	19	222	1.0e-25	110	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
649914026	552	44.34	3	522	11	501	2.0e-117	416	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
649914027	267	25.57	45	263	5	203	1.0e-24	106	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
649914029	344	29.14	5	344	15	408	1.0e-36	147	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
649914030	222	39.13	11	215	11	204	1.0e-31	129	COG2945	Alpha/beta superfamily hydrolase	210
649914031	417	44.61	13	408	9	404	3.0e-120	425	COG4992	Acetylornithine/succinyldiaminopimelate/putrescine aminotransferase	404
649914033	475	46.96	19	474	6	463	0.0e+00	487	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
649914034	357	36.52	9	357	2	350	4.0e-64	238	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
649914037	336	24.78	1	328	1	314	2.0e-34	139	COG0451	Nucleoside-diphosphate-sugar epimerase	314
649914039	256	38.43	1	246	1	251	3.0e-43	168	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
649914041	382	25.24	17	311	8	309	2.0e-23	103	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
649914043	693	31.83	133	683	1	513	2.0e-77	284	COG1657	Squalene cyclase	517
649914044	343	61.77	22	313	1	293	4.0e-109	388	COG0761	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH	294
649914045	590	42.01	1	584	1	552	0.0e+00	469	COG0497	DNA repair ATPase RecN	557
649914046	262	34.63	45	245	12	216	1.0e-33	137	COG0811	Biopolymer transport protein ExbB/TolQ	216
649914047	134	36.57	1	131	1	134	6.0e-25	106	COG0848	Biopolymer transport protein ExbD	137
649914048	262	22.17	52	262	40	244	7.0e-09	54.4	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
649914049	444	29.09	10	442	1	422	2.0e-47	183	COG0823	Periplasmic component of the Tol biopolymer transport system	425
649914051	314	21.18	58	306	28	261	2.0e-21	97	COG1729	Periplasmic TolA-binding protein (function unknown)	262
649914053	1094	66.17	13	414	1	390	0.0e+00	551	COG0458	Carbamoylphosphate synthase large subunit	400
649914054	378	57.37	1	378	2	367	0.0e+00	538	COG0505	Carbamoylphosphate synthase small subunit	368
649914055	111	33.96	1	104	2	105	1.0e-19	88.1	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
649914057	141	29.71	9	139	12	138	3.0e-07	47.7	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
649914058	416	33.25	4	409	8	411	2.0e-64	240	COG4102	Uncharacterized conserved protein, DUF1501 family	418
649914059	727	50	386	727	1	324	2.0e-120	427	COG0022	Pyruvate/2-oxoglutarate/acetoin dehydrogenase complex, dehydrogenase (E1) component	324
649914062	315	23.96	30	313	31	313	1.0e-25	110	COG0668	Small-conductance mechanosensitive channel	316
649914063	714	40.66	15	714	8	667	0.0e+00	571	COG1331	Uncharacterized conserved protein YyaL, SSP411 family, contains thoiredoxin and six-hairpin glycosidase-like domains	667
649914064	685	17.33	244	644	83	457	3.0e-24	107	COG1538	Outer membrane protein TolC	457
649914065	287	42.16	17	284	4	253	1.0e-74	273	COG0101	tRNA U38,U39,U40 pseudouridine synthase TruA	266
649914066	406	24.07	38	403	21	406	9.0e-24	104	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
649914068	550	37.57	53	430	17	344	5.0e-59	222	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
649914071	135	34	30	129	13	111	4.0e-13	67.3	COG2919	Cell division protein FtsB	117
649914073	190	40.12	22	185	9	173	9.0e-19	86.8	COG1268	Biotin transporter BioY	184
649914074	300	48.12	26	291	2	263	1.0e-84	306	COG2107	Predicted periplasmic solute-binding protein	272
649914076	493	30.68	44	480	2	438	2.0e-45	176	COG0534	Na+-driven multidrug efflux pump	455
649914077	119	39.17	1	119	1	120	1.0e-22	98.5	COG1733	DNA-binding transcriptional regulator, HxlR family	120
649914081	959	13.51	77	733	16	624	9.0e-07	49.9	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
649914083	406	24.68	11	393	5	387	1.0e-44	174	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
649914085	432	23.56	27	423	3	339	1.0e-32	134	COG0673	Predicted dehydrogenase	342
649914086	537	31.62	172	528	90	458	5.0e-31	129	COG0531	Amino acid transporter	466
649914087	516	26.79	4	501	1	445	1.0e-25	111	COG0531	Amino acid transporter	466
649914088	218	36.23	15	218	3	207	4.0e-34	138	COG0352	Thiamine monophosphate synthase	211
649914089	257	35.46	20	251	4	249	3.0e-39	155	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
649914090	365	33.73	11	343	2	307	2.0e-44	173	COG2070	NAD(P)H-dependent flavin oxidoreductase YrpB, nitropropane dioxygenase family	336
649914091	468	31.03	25	467	2	394	5.0e-55	208	COG2311	Uncharacterized membrane protein YeiB	394
649914093	457	61.97	1	446	1	446	0.0e+00	602	COG0439	Biotin carboxylase	449
649914094	157	33.78	9	156	1	140	5.0e-21	94	COG0511	Biotin carboxyl carrier protein	140
649914095	358	38.27	3	358	19	383	2.0e-72	266	COG0006	Xaa-Pro aminopeptidase	384
649914096	285	34.45	7	285	2	283	2.0e-38	152	COG1408	Predicted phosphohydrolase, MPP superfamily	284
649914098	581	41.48	5	577	17	607	0.0e+00	504	COG1022	Long-chain acyl-CoA synthetase (AMP-forming)	613
649914099	359	36.09	1	337	1	313	2.0e-61	229	COG2826	Transposase and inactivated derivatives, IS30 family	318
649914100	1512	47.1	689	1220	8	485	0.0e+00	528	COG0069	Glutamate synthase domain 2	485
649914101	146	34	1	145	3	150	6.0e-29	119	COG1438	Arginine repressor	150
649914102	348	41.95	4	348	3	343	1.0e-92	333	COG0002	N-acetyl-gamma-glutamylphosphate reductase	349
649914103	260	43.85	3	257	5	263	1.0e-55	209	COG0548	Acetylglutamate kinase	265
649914104	443	48.28	22	428	1	402	0.0e+00	493	COG4992	Acetylornithine/succinyldiaminopimelate/putrescine aminotransferase	404
649914105	368	50.32	41	348	1	310	8.0e-106	377	COG0078	Ornithine carbamoyltransferase	310
649914106	404	59.09	1	394	3	397	0.0e+00	559	COG0137	Argininosuccinate synthase	403
649914107	466	48.14	1	457	5	459	0.0e+00	483	COG0165	Argininosuccinate lyase	459
649914108	183	38	5	152	3	150	2.0e-26	112	COG1246	N-acetylglutamate synthase or related acetyltransferase, GNAT family	153
649914110	274	37.34	10	245	27	257	5.0e-46	178	COG1119	ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA	257
649914111	205	34.07	10	189	2	183	4.0e-35	141	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
649914112	403	23.96	25	380	1	322	5.0e-39	155	COG0673	Predicted dehydrogenase	342
649914113	319	24.18	51	312	23	272	2.0e-16	80.3	COG1082	Sugar phosphate isomerase/epimerase	274
649914115	443	20.14	28	443	36	447	3.0e-25	109	COG1524	Predicted pyrophosphatase or phosphodiesterase, AlkP superfamily	450
649914116	346	30.86	25	346	29	346	8.0e-62	230	COG0208	Ribonucleotide reductase beta subunit, ferritin-like domain	348
649914117	815	33.74	67	777	1	649	0.0e+00	502	COG0209	Ribonucleotide reductase alpha subunit	696
649914118	582	39.43	1	550	2	544	0.0e+00	462	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
649914119	203	46.33	1	177	1	175	1.0e-51	196	COG0279	Phosphoheptose isomerase	176
649914120	291	59.72	1	288	1	285	2.0e-116	412	COG1209	dTDP-glucose pyrophosphorylase	286
649914121	371	63.35	4	354	2	340	0.0e+00	530	COG1088	dTDP-D-glucose 4,6-dehydratase	340
649914122	199	52.49	1	181	1	171	3.0e-55	208	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase or related enzyme	173
649914123	280	22.39	40	232	1	187	2.0e-10	59.6	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
649914124	449	32.04	116	433	64	389	2.0e-50	194	COG1306	Uncharacterized protein	400
649914125	335	33.02	201	304	5	106	4.0e-08	52.6	COG0607	Rhodanese-related sulfurtransferase	110
649914125	335	33.87	7	188	15	200	1.0e-27	117	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
649914126	681	45.53	1	681	12	694	0.0e+00	714	COG1523	Pullulanase/glycogen debranching enzyme	697
649914127	434	27.76	1	424	2	406	1.0e-50	194	COG1819	UDP:flavonoid glycosyltransferase YjiC, YdhE family	406
649914128	750	52.13	15	725	14	739	0.0e+00	802	COG2183	Transcriptional accessory protein Tex/SPT6	780
649914130	188	46.15	17	172	23	175	7.0e-31	127	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
649914131	361	20.28	1	279	1	250	1.0e-07	51.2	COG5662	Transmembrane transcriptional regulator (anti-sigma factor RsiW)	256
649914133	154	31.71	7	129	1	114	5.0e-12	64.1	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
649914138	384	47.69	17	361	8	311	2.0e-91	329	COG0646	Methionine synthase I (cobalamin-dependent), methyltransferase domain	311
649914139	910	57.18	15	874	10	842	0.0e+00	1071	COG1410	Methionine synthase I, cobalamin-binding domain	842
649914140	204	41.9	2	203	1	210	4.0e-46	177	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
649914141	155	54.25	3	155	2	153	1.0e-31	129	COG3918	Uncharacterized membrane protein	153
649914142	1009	26.59	730	988	103	365	2.0e-36	148	COG4585	Signal transduction histidine kinase	365
649914145	311	19.27	1	298	3	263	1.0e-12	67.8	COG1235	Phosphoribosyl 1,2-cyclic phosphodiesterase	269
649914146	251	35.11	8	230	10	233	5.0e-44	171	COG5424	Pyrroloquinoline quinone (PQQ) biosynthesis protein C	242
649914148	364	31.96	13	343	17	346	2.0e-39	156	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
649914149	584	29.74	81	448	23	402	2.0e-34	141	COG2319	WD40 repeat	466
649914153	603	22.13	246	588	3	334	2.0e-25	111	COG0642	Signal transduction histidine kinase	336
649914154	235	43.36	14	235	3	227	4.0e-61	227	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
649914155	1821	20.47	114	433	1	283	1.0e-03	40.4	COG3386	Sugar lactone lactonase YvrE	307
649914157	543	43.2	12	541	13	549	0.0e+00	518	COG4716	Myosin-crossreactive antigen  (function unknown)	587
649914158	143	25.66	16	127	1	113	2.0e-09	55.3	COG1846	DNA-binding transcriptional regulator, MarR family	126
649914159	413	54.5	5	413	3	411	0.0e+00	467	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
649914160	451	20.76	40	434	3	338	3.0e-31	129	COG0673	Predicted dehydrogenase	342
649914165	465	25.14	1	352	10	350	2.0e-26	113	COG1566	Multidrug resistance efflux pump	352
649914166	253	56	21	243	1	225	4.0e-84	304	COG1136	ABC-type lipoprotein export system, ATPase component	226
649914167	267	23.75	23	261	22	260	1.0e-15	77.3	COG0428	Zinc transporter ZupT	266
649914168	130	36.07	11	129	18	139	1.0e-20	92.3	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
649914169	151	43.55	1	122	4	127	3.0e-25	107	COG1522	DNA-binding transcriptional regulator, Lrp family	154
649914170	281	39.48	18	281	2	265	2.0e-65	242	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
649914171	434	25.42	6	424	3	368	1.0e-52	200	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
649914174	349	21.04	24	349	8	379	2.0e-26	113	COG2309	Leucyl aminopeptidase (aminopeptidase T)	385
649914175	420	29.58	48	397	10	355	1.0e-58	220	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
649914176	1050	48.21	1	1034	1	1018	0.0e+00	1137	COG3696	Cu/Ag efflux pump CusA	1027
649914177	389	28.39	69	373	54	356	8.0e-21	95.2	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
649914178	444	24.88	34	432	22	438	2.0e-25	111	COG1538	Outer membrane protein TolC	457
649914179	387	33.59	124	378	78	334	6.0e-37	148	COG0642	Signal transduction histidine kinase	336
649914180	468	49.89	1	454	2	456	0.0e+00	508	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
649914181	195	33.33	7	186	5	196	4.0e-32	131	COG0406	Broad specificity phosphatase PhoE	208
649914184	202	38.31	38	191	15	165	6.0e-28	117	COG4333	Uncharacterized protein	167
649914186	623	51.83	2	623	5	622	0.0e+00	736	COG0326	Molecular chaperone, HSP90 family	623
649914187	798	34.11	7	785	38	832	0.0e+00	484	COG1643	HrpA-like RNA helicase	845
649914190	374	20.66	1	292	30	314	1.0e-11	64.6	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
649914191	237	42.19	1	237	1	227	7.0e-62	230	COG4947	Esterase/lipase superfamily enzyme	227
649914192	285	24.05	31	280	12	264	2.0e-26	113	COG2819	Predicted hydrolase of the alpha/beta superfamily	264
649914193	86	48.68	2	76	4	79	6.0e-19	85.7	COG0228	Ribosomal protein S16	87
649914194	88	46.58	10	82	4	76	2.0e-15	74.1	COG1837	Predicted RNA-binding protein YlqC, contains KH domain, UPF0109 family	76
649914195	188	28.34	1	185	1	174	1.0e-27	116	COG0806	Ribosomal 30S subunit maturation factor RimM, required for 16S rRNA processing	174
649914197	268	49.24	2	263	1	236	2.0e-87	315	COG0336	tRNA G37 N-methylase TrmD	240
649914198	315	34.45	1	307	1	326	1.0e-55	210	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
649914199	118	56.36	5	113	4	113	6.0e-32	129	COG0335	Ribosomal protein L19	115
649914201	248	46.67	38	229	1	194	2.0e-57	215	COG0164	Ribonuclease HII	199
649914202	238	31.39	1	223	14	222	1.0e-27	116	COG2120	N-acetylglucosaminyl deacetylase, LmbE family	237
649914204	286	36.99	42	286	1	245	9.0e-52	197	COG1414	DNA-binding transcriptional regulator, IclR family	246
649914206	499	30.46	2	414	4	393	4.0e-56	212	COG1696	D-alanyl-lipoteichoic acid acyltransferase DltB, MBOAT superfamily	425
649914207	323	29.55	7	323	3	311	2.0e-48	186	COG1482	Mannose-6-phosphate isomerase, class I	312
649914208	338	36.76	56	326	20	280	5.0e-59	221	COG1398	Fatty-acid desaturase	289
649914210	249	40.08	7	242	3	229	5.0e-49	187	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
649914211	782	25.41	1	365	1	364	6.0e-45	176	COG0795	Lipopolysaccharide export LptBFGC system, permease protein LptF	364
649914212	206	35.8	28	189	46	203	2.0e-27	115	COG0545	FKBP-type peptidyl-prolyl cis-trans isomerase	205
649914213	582	40.56	5	575	4	567	3.0e-126	446	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
649914214	324	28.95	10	196	14	203	9.0e-27	114	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
649914215	419	35.53	27	416	5	338	4.0e-62	232	COG1566	Multidrug resistance efflux pump	352
649914216	480	25.92	65	467	42	443	3.0e-31	130	COG1538	Outer membrane protein TolC	457
649914217	363	31.52	2	360	1	342	2.0e-45	176	COG0673	Predicted dehydrogenase	342
649914218	371	29.27	6	365	1	342	1.0e-40	160	COG0673	Predicted dehydrogenase	342
649914219	407	46.37	9	407	15	404	4.0e-112	398	COG1364	N-acetylglutamate synthase (N-acetylornithine aminotransferase)	404
649914220	890	56.16	16	887	13	884	0.0e+00	1146	COG2609	Pyruvate dehydrogenase complex, dehydrogenase (E1) component	887
649914221	272	20.59	10	265	24	323	2.0e-17	83	COG1071	TPP-dependent pyruvate or acetoin dehydrogenase subunit alpha	358
649914223	312	35.46	4	307	1	308	7.0e-51	194	COG0451	Nucleoside-diphosphate-sugar epimerase	314
649914224	474	48.85	6	440	2	413	0.0e+00	491	COG1004	UDP-glucose 6-dehydrogenase	414
649914225	383	22.56	1	383	1	380	7.0e-28	118	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649914226	210	23.86	22	192	3	178	8.0e-20	90.3	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
649914228	447	43.75	3	258	1	248	1.0e-76	280	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
649914229	589	34.15	64	587	1	523	5.0e-97	348	COG4986	ABC-type anion transport system, duplicated permease component	523
649914231	443	18.16	23	377	28	407	6.0e-10	59.2	COG0366	Glycosidase	505
649914234	881	20.57	491	881	3	419	2.0e-17	84.8	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
649914235	947	20.73	604	947	72	419	3.0e-16	81.3	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
649914236	113	31.96	10	106	4	100	4.0e-15	73.3	COG1695	DNA-binding transcriptional regulator, PadR family	138
649914238	231	50.22	1	226	3	228	3.0e-83	301	COG0047	Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain	231
649914239	266	32.4	1	243	1	241	4.0e-42	165	COG4464	Tyrosine-protein phosphatase YwqE	254
649914240	244	40.64	5	242	2	250	1.0e-40	160	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
649914242	98	56.84	4	98	2	96	1.0e-30	124	COG0234	Co-chaperonin GroES (HSP10)	96
649914243	557	47.68	1	545	2	524	0.0e+00	484	COG0459	Chaperonin GroEL (HSP60 family)	524
649914244	415	20.13	44	343	23	256	2.0e-09	57.7	COG2333	Metal-dependent hydrolase, beta-lactamase superfamily II	293
649914246	250	22.62	85	250	2	169	1.0e-11	63.9	COG3652	Predicted outer membrane protein	170
649914249	154	45.53	16	138	6	128	5.0e-33	133	COG5478	Low affinity Fe/Cu permease	141
649914251	339	45.48	1	326	1	329	6.0e-82	297	COG2008	Threonine aldolase	342
649914252	383	33.25	1	380	31	411	3.0e-77	282	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
649914253	656	36.64	29	642	2	567	1.0e-123	437	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
649914254	203	22.01	1	202	9	217	9.0e-13	67.2	COG1392	Uncharacterized conserved protein YkaA, distantly related to PhoU, UPF0111/DUF47 family	217
649914255	355	36.15	5	342	1	324	2.0e-53	203	COG0306	Phosphate/sulfate permease	326
649914256	401	37.57	7	378	2	363	2.0e-79	289	COG0763	Lipid A disaccharide synthetase	381
649914260	531	34.51	5	497	14	514	8.0e-111	394	COG1640	4-alpha-glucanotransferase	520
649914266	392	23.41	2	382	4	401	1.0e-18	87.7	COG3182	Uncharacterized iron-regulated membrane protein	442
649914267	795	26.38	152	791	79	746	1.0e-54	208	COG4774	Outer membrane receptor for monomeric catechols	750
649914268	342	24.63	4	333	2	317	2.0e-24	107	COG0226	ABC-type phosphate transport system, periplasmic component	318
649914269	545	26.17	42	473	82	480	6.0e-55	209	COG5434	Polygalacturonase	542
649914270	238	46.49	5	232	3	228	5.0e-58	217	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
649914271	448	34.5	83	445	88	447	2.0e-54	207	COG5002	Signal transduction histidine kinase	459
649914272	488	32.39	145	460	19	327	2.0e-41	163	COG0642	Signal transduction histidine kinase	336
649914273	224	44.3	1	222	1	227	8.0e-53	200	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
649914283	287	39.83	171	287	5	122	1.0e-19	90.3	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
649914286	318	25.17	27	308	6	277	4.0e-22	99.2	COG3618	Predicted metal-dependent hydrolase, TIM-barrel fold	279
649914289	206	35.64	8	195	1	181	3.0e-26	111	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
649914290	156	34.72	8	150	1	141	1.0e-11	62.7	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
649914291	266	31.44	7	233	5	222	9.0e-36	144	COG5429	Uncharacterized protein	261
649914294	293	42.22	10	275	2	270	4.0e-78	284	COG3220	Uncharacterized conserved protein, UPF0276 family	282
649914301	679	26.98	46	650	1	617	2.0e-73	270	COG1506	Dipeptidyl aminopeptidase/acylaminoacyl peptidase	620
649914302	987	11.31	121	856	37	730	3.0e-05	44.9	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
649914304	306	38.78	4	304	1	307	5.0e-56	211	COG0524	Sugar or nucleoside kinase, ribokinase family	311
649914307	723	26.98	479	722	51	312	2.0e-24	107	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
649914308	326	43.64	1	326	3	332	4.0e-88	318	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
649914310	896	19.25	496	896	1	419	1.0e-15	79.4	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
649914312	231	41.59	6	229	3	227	1.0e-54	206	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
649914318	316	40.73	13	311	4	300	7.0e-77	280	COG0031	Cysteine synthase	300
649914319	236	17.97	9	234	25	277	5.0e-08	51.6	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
649914320	705	37.8	55	705	6	654	0.0e+00	555	COG3590	Predicted metalloendopeptidase	654
649914323	306	27.11	25	295	2	279	9.0e-26	110	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
649914325	440	27.14	1	418	2	401	2.0e-42	167	COG1819	UDP:flavonoid glycosyltransferase YjiC, YdhE family	406
649914330	223	20.73	13	201	2	194	6.0e-08	51.2	COG1309	DNA-binding transcriptional regulator, AcrR family	201
649914331	1064	27.36	2	1045	1	1008	0.0e+00	662	COG0841	Multidrug efflux pump subunit AcrB	1009
649914332	433	30.31	36	417	1	367	5.0e-28	119	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
649914333	479	34.9	15	479	1	454	1.0e-57	217	COG1538	Outer membrane protein TolC	457
649914334	207	23.78	8	170	2	165	3.0e-05	41.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
649914335	250	43.75	2	248	1	251	1.0e-48	186	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
649914336	200	34.39	1	181	2	189	2.0e-30	125	COG2085	Predicted dinucleotide-binding enzyme	211
649914337	133	34.11	1	129	1	129	1.0e-21	95.8	COG3631	Ketosteroid isomerase-related protein	133
649914338	325	35.92	215	317	19	121	3.0e-21	96.1	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
649914339	244	36.51	2	242	1	251	4.0e-43	168	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
649914340	509	30.83	44	490	25	478	2.0e-75	276	COG1621	Sucrose-6-phosphate hydrolase SacC, GH32 family	486
649914341	326	28.15	8	288	3	297	1.0e-32	134	COG0524	Sugar or nucleoside kinase, ribokinase family	311
649914342	431	28.76	199	411	5	204	3.0e-14	73.4	COG2755	Lysophospholipase L1 or related esterase	216
649914343	365	24.38	50	364	2	312	4.0e-25	109	COG0657	Acetyl esterase/lipase	312
649914345	427	22.42	203	417	10	204	3.0e-11	63.4	COG2755	Lysophospholipase L1 or related esterase	216
649914346	285	24.15	3	251	1	261	3.0e-28	119	COG1082	Sugar phosphate isomerase/epimerase	274
649914347	391	28.19	137	388	59	311	1.0e-26	114	COG0657	Acetyl esterase/lipase	312
649914349	365	28.12	36	360	8	331	5.0e-42	165	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
649914352	260	24.7	6	224	13	259	7.0e-14	71.2	COG5486	Predicted metal-binding membrane protein	283
649914354	260	23.27	1	242	8	252	8.0e-11	61.2	COG0730	Uncharacterized membrane protein YfcA	258
649914355	116	32.35	8	109	13	113	5.0e-08	49.9	COG3169	Uncharacterized conserved protein, DUF486 family	116
649914357	861	20	406	853	119	450	1.0e-16	82.1	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
649914359	283	25.82	46	273	9	236	1.0e-11	64.1	COG0528	Uridylate kinase	238
649914361	154	52.94	1	151	1	153	3.0e-55	207	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
649914362	767	24.76	82	765	35	725	5.0e-80	292	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
649914363	112	24.35	1	111	15	126	1.0e-06	45	COG2010	Cytochrome c, mono- and diheme variants	150
649914366	538	19.51	71	231	49	199	3.0e-04	40.4	COG3637	Opacity protein and related surface antigens	199
649914370	787	30.56	7	114	2	107	2.0e-13	71.5	COG3710	DNA-binding winged helix-turn-helix (wHTH) domain	148
649914375	415	21.29	57	402	37	375	3.0e-17	83.2	COG3550	Serine/threonine protein kinase HipA, toxin component of the HipAB toxin-antitoxin module	392
649914376	195	18.68	13	194	18	197	1.0e-05	43.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
649914377	221	33.71	42	216	4	156	4.0e-25	108	COG1225	Peroxiredoxin	157
649914378	410	20.15	6	410	1	394	4.0e-22	99.5	COG2814	Predicted arabinose efflux permease, MFS family	394
649914379	322	46.95	13	322	5	305	5.0e-85	307	COG0492	Thioredoxin reductase	305
649914385	312	26.03	4	291	1	286	5.0e-23	101	COG0583	DNA-binding transcriptional regulator, LysR family	297
649914386	419	31.51	125	351	62	282	3.0e-24	106	COG4974	Site-specific recombinase XerD	300
649914391	261	48.22	8	255	2	251	8.0e-52	197	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
649914392	334	48.31	13	332	2	324	5.0e-76	278	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
649914393	226	28.02	1	226	2	217	3.0e-20	92.3	COG1985	Pyrimidine reductase, riboflavin biosynthesis	218
649914395	484	35.07	44	484	11	447	2.0e-63	236	COG1538	Outer membrane protein TolC	457
649914397	1055	30.38	2	1045	1	1006	0.0e+00	674	COG0841	Multidrug efflux pump subunit AcrB	1009
649914398	330	40.51	1	312	1	310	1.0e-87	316	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
649914399	178	35.61	41	170	1	131	6.0e-19	87.2	COG1917	Cupin domain protein related to quercetin dioxygenase	131
649914400	399	38.08	55	395	5	337	5.0e-101	361	COG1064	D-arabinose 1-dehydrogenase, Zn-dependent alcohol dehydrogenase family	339
649914401	294	25.2	173	294	2	122	5.0e-16	78.5	COG0599	Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family	124
649914402	255	44.92	3	253	1	251	9.0e-53	200	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
649914403	335	33.07	201	327	1	127	7.0e-18	84.9	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
649914404	529	32.02	9	186	2	174	4.0e-21	96.5	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
649914413	186	35.26	28	183	12	163	8.0e-34	136	COG4333	Uncharacterized protein	167
649914415	664	18.86	165	609	90	570	2.0e-22	101	COG3505	Type IV secretory pathway, VirD4 component, TraG/TraD family ATPase	596
649914420	326	40.48	13	304	49	336	3.0e-59	222	COG4962	Pilus assembly protein, ATPase of CpaF family	355
649914421	116	43.1	1	115	1	115	2.0e-26	110	COG4683	Uncharacterized protein	120
649914423	261	22.64	22	230	25	220	4.0e-04	38.8	COG3701	Type IV secretory pathway, TrbF components	228
649914430	418	21.1	111	407	48	352	7.0e-21	95.5	COG2948	Type IV secretory pathway, VirB10 components	360
649914432	789	22.7	25	751	21	751	2.0e-48	187	COG3451	Type IV secretory pathway, VirB4 component	796
649914435	338	25.5	7	300	1	296	6.0e-25	108	COG0583	DNA-binding transcriptional regulator, LysR family	297
649914437	419	26.47	114	396	2	281	3.0e-22	99.9	COG4974	Site-specific recombinase XerD	300
649914438	292	42.54	12	271	15	278	1.0e-57	216	COG1398	Fatty-acid desaturase	289
649914439	449	30.81	107	449	1	332	4.0e-39	156	COG0642	Signal transduction histidine kinase	336
649914440	243	40	15	234	3	226	3.0e-55	208	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
649914444	486	44.37	24	473	24	485	1.0e-119	423	COG1953	Cytosine/uracil/thiamine/allantoin permease	497
649914445	342	31.27	4	341	1	328	1.0e-63	236	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
649914446	451	40.43	254	441	1	178	1.0e-38	154	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
649914447	312	28.16	74	247	27	180	3.0e-15	76.1	COG0684	Regulator of RNase E activity RraA	210
649914448	313	26.74	15	267	33	287	3.0e-28	119	COG0657	Acetyl esterase/lipase	312
649914449	544	15.17	41	544	76	603	1.0e-26	115	COG1874	Beta-galactosidase GanA	673
649914451	792	34.03	169	775	141	735	2.0e-130	460	COG1501	Alpha-glucosidase, glycosyl hydrolase family GH31	772
649914456	401	44.33	1	401	4	403	0.0e+00	488	COG4992	Acetylornithine/succinyldiaminopimelate/putrescine aminotransferase	404
649914460	357	23.18	12	336	9	362	5.0e-17	82.1	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
649914461	274	19.01	1	266	3	285	1.0e-10	60.5	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
649914462	326	33.92	54	311	97	378	4.0e-27	115	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649914463	362	17.63	1	269	1	277	4.0e-03	36.2	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649914464	295	18.83	1	287	1	305	2.0e-16	79.8	COG1216	Glycosyltransferase, GT2 family	305
649914465	210	21.88	76	171	23	118	5.0e-11	61.4	COG1917	Cupin domain protein related to quercetin dioxygenase	131
649914466	365	28.37	12	361	9	368	5.0e-29	122	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
649914468	337	27.2	24	256	9	239	9.0e-19	87.9	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
649914469	732	26.3	26	455	19	458	6.0e-50	192	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
649914470	420	26.9	130	407	89	375	1.0e-23	104	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649914471	384	22.51	1	373	1	381	1.0e-26	114	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649914472	378	30.08	27	374	8	372	2.0e-25	110	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
649914474	396	46.31	10	393	4	395	2.0e-122	432	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
649914476	281	30.08	1	264	1	235	2.0e-30	126	COG3394	Predicted glycoside hydrolase or deacetylase ChbG, UPF0249 family	257
649914478	215	48.26	12	212	1	193	3.0e-57	214	COG0807	GTP cyclohydrolase II	193
649914480	249	30.25	77	235	30	190	2.0e-19	89.9	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
649914481	665	40.06	1	643	3	581	0.0e+00	550	COG0322	Excinuclease UvrABC, nuclease subunit	581
649914482	142	23.66	4	126	1	131	3.0e-06	44.7	COG1848	Predicted nucleic acid-binding protein, contains PIN domain	140
649914484	680	21.53	36	664	22	604	2.0e-23	104	COG4206	Outer membrane cobalamin receptor protein	608
649914485	298	43.1	3	298	1	295	4.0e-76	278	COG2321	Predicted metalloprotease	295
649914486	807	34.39	28	805	33	759	6.0e-127	448	COG3537	Putative alpha-1,2-mannosidase	768
649914487	305	23.53	33	303	62	329	5.0e-17	82	COG2367	Beta-lactamase class A	329
649914488	545	28.26	36	347	30	331	1.0e-51	197	COG3673	Uncharacterized protein, PA2063/DUF2235 family	423
649914489	179	28.46	41	168	4	133	2.0e-18	85.4	COG4319	Ketosteroid isomerase homolog	137
649914493	472	28.38	36	465	20	447	3.0e-31	129	COG0531	Amino acid transporter	466
649914494	484	41.75	1	483	1	484	0.0e+00	475	COG0297	Glycogen synthase	487
649914495	264	38.4	1	263	1	255	3.0e-69	255	COG0030	16S rRNA A1518 and A1519 N6-dimethyltransferase RsmA/KsgA/DIM1 (may also have DNA glycosylase/AP lyase activity)	259
649914498	168	54.72	5	163	2	155	8.0e-45	173	COG0817	Holliday junction resolvasome RuvABC endonuclease subunit	160
649914499	256	60.31	1	256	5	260	8.0e-98	350	COG2022	Thiamin biosynthesis thiazole synthase ThiGH, ThiG subunit	262
649914502	381	25.69	58	376	31	335	6.0e-20	92	COG3240	Phospholipase/lecithinase/hemolysin	370
649914503	292	35.29	4	291	2	253	5.0e-22	98.5	COG1989	Prepilin signal peptidase PulO (type II secretory pathway) or related peptidase	254
649914505	135	45.45	9	129	7	121	1.0e-26	112	COG0838	NADH:ubiquinone oxidoreductase subunit 3 (chain A)	123
649914506	160	40.88	23	159	16	152	6.0e-37	146	COG0852	NADH:ubiquinone oxidoreductase 27 kD subunit (chain C)	176
649914507	426	58.66	40	426	12	398	0.0e+00	567	COG0649	NADH:ubiquinone oxidoreductase 49 kD subunit (chain D)	398
649914509	169	38.46	8	163	4	159	5.0e-43	167	COG1905	NADH:ubiquinone oxidoreductase 24 kD subunit (chain E)	160
649914510	440	50.24	7	424	6	424	0.0e+00	539	COG1894	NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F)	424
649914511	801	31.24	3	721	1	672	1.0e-125	444	COG1034	NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)	693
649914512	352	50.86	1	350	1	329	1.0e-90	327	COG1005	NADH:ubiquinone oxidoreductase subunit 1 (chain H)	332
649914513	168	40.72	1	167	3	165	6.0e-15	73.7	COG0839	NADH:ubiquinone oxidoreductase subunit 6 (chain J)	166
649914514	100	57.58	1	99	1	99	7.0e-22	95.5	COG0713	NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K)	100
649914515	681	41.68	6	670	1	604	3.0e-127	449	COG1009	NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit	606
649914516	530	41.65	8	511	5	495	2.0e-103	369	COG1008	NADH:ubiquinone oxidoreductase subunit 4 (chain M)	497
649914517	513	41.77	3	488	1	475	2.0e-92	333	COG1007	NADH:ubiquinone oxidoreductase subunit 2 (chain N)	475
649914518	101	40.85	28	98	3	73	3.0e-05	40.2	COG0636	FoF1-type ATP synthase, membrane subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K	79
649914519	243	37.62	45	242	37	246	1.0e-35	143	COG0356	FoF1-type ATP synthase, membrane subunit a	246
649914523	561	50.85	20	546	6	502	0.0e+00	630	COG1190	Lysyl-tRNA synthetase (class II)	502
649914524	264	53.53	1	264	1	259	1.0e-88	319	COG1692	Calcineurin-like phosphoesterase	266
649914526	1288	29.85	179	1282	89	1160	0.0e+00	464	COG1196	Chromosome segregation ATPase	1163
649914527	307	34.98	17	296	9	246	6.0e-64	237	COG0152	Phosphoribosylaminoimidazole-succinocarboxamide synthase	247
649914534	394	24.86	19	387	1	338	5.0e-40	158	COG2222	Fructoselysine-6-P-deglycase FrlB and related proteins with duplicated sugar isomerase (SIS) domain	340
649914535	453	19.03	56	424	5	332	2.0e-17	83.8	COG0673	Predicted dehydrogenase	342
649914536	419	25.37	31	419	4	371	2.0e-25	110	COG4299	Predicted acyltransferase	371
649914537	252	43.25	1	252	2	252	3.0e-62	232	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
649914545	229	31.51	61	205	14	157	6.0e-17	81.3	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
649914549	207	18.78	1	206	5	217	3.0e-05	41.8	COG1392	Uncharacterized conserved protein YkaA, distantly related to PhoU, UPF0111/DUF47 family	217
649914550	351	34.49	3	342	1	323	1.0e-53	203	COG0306	Phosphate/sulfate permease	326
649914552	194	46.07	1	191	19	208	2.0e-54	204	COG2808	Predicted FMN-binding regulatory protein PaiB	209
649914553	594	43.33	58	510	20	474	3.0e-116	413	COG0539	Ribosomal protein S1	541
649914554	322	28.48	1	307	1	308	1.0e-30	127	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
649914557	526	44.72	36	526	8	488	0.0e+00	560	COG0397	Uncharacterized conserved protein YdiU, UPF0061 family	488
649914561	369	25.92	6	351	4	345	1.0e-26	114	COG0644	Dehydrogenase (flavoprotein)	396
649914563	342	28.99	1	342	4	368	1.0e-25	111	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
649914564	180	32.77	5	180	1	174	1.0e-27	115	COG3040	Bacterial lipocalin	174
649914565	193	37.65	25	184	15	176	1.0e-24	106	COG1268	Biotin transporter BioY	184
649914566	141	45.59	1	136	1	135	2.0e-33	134	COG3543	Uncharacterized protein	135
649914567	149	23.36	34	140	19	123	4.0e-07	47.6	COG1846	DNA-binding transcriptional regulator, MarR family	126
649914568	109	35.35	7	105	4	102	4.0e-15	73.3	COG1695	DNA-binding transcriptional regulator, PadR family	138
649914571	472	48.05	24	472	5	457	4.0e-121	428	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
649914572	640	22.39	233	624	85	448	2.0e-28	121	COG1538	Outer membrane protein TolC	457
649914573	848	19.07	23	435	4	418	2.0e-16	82.1	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
649914574	240	49.55	7	228	1	223	5.0e-78	284	COG1136	ABC-type lipoprotein export system, ATPase component	226
649914575	419	23.86	10	311	7	289	1.0e-18	88.1	COG1566	Multidrug resistance efflux pump	352
649914576	116	33.33	7	108	4	104	2.0e-11	61	COG1695	DNA-binding transcriptional regulator, PadR family	138
649914577	887	15.22	97	483	4	417	1.0e-14	75.9	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
649914579	435	53.26	6	433	7	436	2.0e-110	393	COG2252	Xanthine/uracil/vitamin C permease, AzgA family	436
649914581	553	40	274	544	4	268	7.0e-66	245	COG0171	NH3-dependent NAD+ synthetase	268
649914582	510	43.16	278	509	1	224	1.0e-64	241	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
649914583	340	47.11	92	332	5	246	6.0e-71	261	COG1127	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, ATPase component MlaF	263
649914584	226	28.71	1	201	4	189	8.0e-29	120	COG0746	Molybdopterin-guanine dinucleotide biosynthesis protein A	192
649914585	457	27.33	3	457	1	407	3.0e-56	213	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
649914586	259	27.35	12	235	1	231	1.0e-17	83.8	COG4106	Trans-aconitate methyltransferase	257
649914587	108	40	1	108	1	110	3.0e-18	83.4	COG0607	Rhodanese-related sulfurtransferase	110
649914588	475	49.13	8	467	5	454	0.0e+00	475	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
649914589	629	24.66	191	617	30	447	9.0e-28	118	COG5002	Signal transduction histidine kinase	459
649914592	271	20	43	257	6	209	4.0e-10	58.8	COG2755	Lysophospholipase L1 or related esterase	216
649914593	319	40.45	1	314	2	300	7.0e-79	287	COG4974	Site-specific recombinase XerD	300
649914594	311	44.04	9	302	5	300	1.0e-76	280	COG4974	Site-specific recombinase XerD	300
649914596	152	31.93	1	152	2	167	6.0e-23	100	COG0622	Predicted phosphodiesterase	172
649914598	317	51.59	6	317	2	315	2.0e-92	332	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
649914599	481	38.19	6	457	4	428	3.0e-93	335	COG1253	Hemolysin or related protein, contains CBS domains	429
649914601	263	27.75	44	261	2	209	8.0e-20	91.1	COG0560	Phosphoserine phosphatase	212
649914602	157	29.93	23	154	10	141	1.0e-09	56.2	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
649914603	422	29.23	7	413	7	409	8.0e-60	224	COG1914	Mn2+ and Fe2+ transporters of the NRAMP family	416
649914605	146	25	10	142	7	146	2.0e-13	68.1	COG2172	Anti-sigma regulatory factor (Ser/Thr protein kinase)	146
649914606	115	27.59	1	115	1	116	3.0e-09	53.9	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
649914607	209	45.83	17	205	1	185	2.0e-48	185	COG1704	Uncharacterized conserved protein	185
649914608	282	31.91	6	282	1	271	1.0e-37	150	COG1512	Uncharacterized membrane protein YgcG, contains a TPM-fold domain	271
649914609	218	27.33	65	211	21	169	2.0e-11	62.4	COG3652	Predicted outer membrane protein	170
649914610	700	51.66	8	697	7	680	0.0e+00	804	COG1770	Protease II	682
649914611	631	39.69	39	610	1	566	3.0e-125	442	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
649914613	298	25	132	282	48	192	6.0e-20	91.6	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
649914615	1189	21.14	1	1156	1	1115	2.0e-75	278	COG1074	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)	1139
649914618	856	15.05	82	687	27	659	8.0e-04	39.9	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
649914619	325	25.17	1	297	2	291	8.0e-23	101	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
649914621	501	47.11	23	501	1	460	0.0e+00	488	COG0147	Anthranilate/para-aminobenzoate synthases component I	462
649914622	409	25.84	1	404	1	403	5.0e-31	128	COG1668	ABC-type Na+ efflux pump, permease component	407
649914623	305	45.15	7	303	1	299	2.0e-88	319	COG4152	ABC-type uncharacterized transport system, ATPase component	300
649914624	222	30.09	4	214	10	224	4.0e-28	118	COG1802	DNA-binding transcriptional regulator, GntR family	230
649914625	749	33.71	406	747	7	344	3.0e-56	213	COG1363	Putative aminopeptidase FrvX	355
649914628	343	29.23	7	325	2	314	6.0e-40	158	COG0451	Nucleoside-diphosphate-sugar epimerase	314
649914630	426	19.19	52	370	44	382	5.0e-05	42.8	COG3307	O-antigen ligase	424
649914631	156	24.74	58	153	25	112	8.0e-07	46.5	COG2863	Cytochrome c553	121
649914634	299	37.55	38	281	11	252	2.0e-56	212	COG1922	UDP-N-acetyl-D-mannosaminuronic acid transferase, WecB/TagA/CpsF family	253
649914635	386	46.96	202	379	37	217	4.0e-51	195	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
649914636	396	21.88	1	371	1	378	1.0e-29	124	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649914640	1026	29.29	332	524	43	239	7.0e-22	100	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
649914643	404	58.82	3	206	1	203	5.0e-79	288	COG0108	3,4-dihydroxy-2-butanone 4-phosphate synthase	203
649914644	312	20.53	11	285	9	284	1.0e-12	67.3	COG5285	Ectoine hydroxylase-related dioxygenase, phytanoyl-CoA dioxygenase (PhyH) family	299
649914647	445	25.6	19	431	1	406	4.0e-46	179	COG1819	UDP:flavonoid glycosyltransferase YjiC, YdhE family	406
649914648	415	23.5	40	365	26	420	1.0e-16	81.3	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
649914650	497	23.23	13	396	17	406	1.0e-33	137	COG1032	Radical SAM superfamily enzyme YgiQ, UPF0313 family	490
649914651	218	51.24	1	201	1	193	7.0e-59	220	COG0807	GTP cyclohydrolase II	193
649914654	747	44.94	1	719	6	662	0.0e+00	705	COG1200	RecG-like helicase	677
649914655	145	34.88	1	124	2	128	9.0e-13	66	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
649914656	305	37.41	14	304	8	291	2.0e-52	199	COG0384	Predicted epimerase YddE/YHI9, PhzF superfamily	291
649914657	218	38.05	1	199	1	193	2.0e-58	219	COG0450	Alkyl hydroperoxide reductase subunit AhpC (peroxiredoxin)	194
649914659	883	17.76	494	882	1	418	3.0e-14	74.4	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
649914660	114	36.36	4	102	2	100	1.0e-16	78.7	COG1695	DNA-binding transcriptional regulator, PadR family	138
649914661	471	35.53	18	471	1	447	2.0e-62	233	COG1538	Outer membrane protein TolC	457
649914662	1078	45.12	1	1031	2	1007	0.0e+00	891	COG0841	Multidrug efflux pump subunit AcrB	1009
649914663	413	26.63	18	397	6	365	4.0e-27	115	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
649914664	232	20.59	17	220	4	201	6.0e-07	48.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
649914665	516	20.91	11	472	7	466	2.0e-15	77.5	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
649914667	402	34.92	12	384	26	368	1.0e-71	264	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
649914668	402	32.67	97	394	8	309	3.0e-45	176	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
649914669	252	38.19	1	246	1	251	9.0e-40	157	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
649914670	405	22.57	59	400	4	341	5.0e-25	109	COG0673	Predicted dehydrogenase	342
649914671	463	22.94	35	416	1	321	7.0e-28	118	COG0673	Predicted dehydrogenase	342
649914675	192	24.08	2	192	10	200	7.0e-09	53.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
649914678	276	33.64	69	276	29	238	1.0e-28	120	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
649914679	385	30.8	132	385	55	298	2.0e-28	120	COG2382	Enterochelin esterase or related enzyme	299
649914680	482	23.54	39	481	9	464	1.0e-25	111	COG0531	Amino acid transporter	466
649914682	333	32.56	1	331	2	348	6.0e-56	211	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
649914684	110	27.93	1	109	1	104	3.0e-09	53.7	COG3254	L-rhamnose mutarotase	105
649914685	777	25.92	63	550	10	430	3.0e-43	170	COG3669	Alpha-L-fucosidase	430
649914686	555	28.17	71	495	1	373	6.0e-78	285	COG3669	Alpha-L-fucosidase	430
649914688	697	24.01	47	692	11	666	1.0e-56	215	COG1874	Beta-galactosidase GanA	673
649914689	529	29.46	64	527	1	426	2.0e-86	313	COG3664	Beta-xylosidase	428
649914691	353	38.58	4	339	2	333	9.0e-77	280	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
649914692	264	30.89	21	261	1	246	3.0e-35	142	COG1414	DNA-binding transcriptional regulator, IclR family	246
649914694	473	31.96	147	459	47	336	2.0e-35	143	COG0642	Signal transduction histidine kinase	336
649914695	245	41.59	12	235	3	227	5.0e-51	194	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
649914696	436	30.06	80	430	24	372	3.0e-36	146	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
649914697	1160	36.46	2	777	1	771	0.0e+00	690	COG0841	Multidrug efflux pump subunit AcrB	1009
649914698	1036	35.66	2	1015	1	1009	0.0e+00	863	COG0841	Multidrug efflux pump subunit AcrB	1009
649914699	506	37.21	66	501	36	456	3.0e-56	213	COG1538	Outer membrane protein TolC	457
649914702	424	21.07	10	369	39	406	3.0e-12	66.7	COG1538	Outer membrane protein TolC	457
649914705	251	41.05	19	245	3	229	4.0e-51	194	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
649914712	99	41.33	16	90	1	75	3.0e-14	69.8	COG1837	Predicted RNA-binding protein YlqC, contains KH domain, UPF0109 family	76
649914715	494	28.66	18	327	1	322	2.0e-34	140	COG3344	Retron-type reverse transcriptase	328
649914716	133	32.12	1	128	2	137	3.0e-24	104	COG0394	Protein-tyrosine-phosphatase	139
649914717	136	35.35	1	98	8	106	9.0e-12	62.9	COG0640	DNA-binding transcriptional regulator, ArsR family	110
649914718	373	51.46	18	359	7	339	3.0e-93	335	COG0798	Arsenite efflux pump ArsB, ACR3 family	342
649914719	102	26.92	3	102	1	104	2.0e-07	47.5	COG1695	DNA-binding transcriptional regulator, PadR family	138
649914720	482	23.94	47	471	43	443	1.0e-21	98.3	COG1538	Outer membrane protein TolC	457
649914721	1048	26.41	7	1027	6	1009	0.0e+00	576	COG0841	Multidrug efflux pump subunit AcrB	1009
649914722	363	28.61	7	363	19	365	5.0e-22	99	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
649914725	667	20.49	2	280	5	271	4.0e-08	53.9	COG1689	Uncharacterized protein	274
649914728	326	30.36	28	326	31	322	7.0e-59	220	COG0598	Mg2+ and Co2+ transporter CorA	322
649914729	230	30.05	1	211	20	232	3.0e-28	118	COG1738	Uncharacterized PurR-regulated membrane protein YhhQ, DUF165 family	233
649914734	414	32.88	45	408	3	313	8.0e-54	204	COG2355	Zn-dependent dipeptidase, microsomal dipeptidase homolog	313
649914735	308	42.23	6	301	2	278	2.0e-79	289	COG1091	dTDP-4-dehydrorhamnose reductase	281
649914736	383	39.14	12	358	2	331	2.0e-97	349	COG0836	Mannose-1-phosphate guanylyltransferase	333
649914737	370	39.24	29	368	2	307	3.0e-61	229	COG2017	Galactose mutarotase or related enzyme	308
649914738	396	37.13	51	392	33	357	2.0e-75	276	COG4225	Rhamnogalacturonyl hydrolase YesR	357
649914739	331	34.74	6	329	1	330	6.0e-59	221	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
649914740	330	30.55	37	304	89	392	2.0e-41	163	COG4677	Pectin methylesterase and related acyl-CoA thioesterases	405
649914743	1204	22.71	52	917	200	921	6.0e-53	203	COG0383	Alpha-mannosidase	943
649914744	396	31.73	4	390	2	350	1.0e-49	191	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
649914746	290	34.07	9	141	8	140	5.0e-20	91.9	COG3710	DNA-binding winged helix-turn-helix (wHTH) domain	148
649914749	131	29.57	9	119	15	127	4.0e-06	43.7	COG2246	Putative flippase GtrA (transmembrane translocase of bactoprenol-linked glucose)	139
649914750	225	49.55	6	223	1	220	3.0e-74	271	COG1136	ABC-type lipoprotein export system, ATPase component	226
649914751	387	19.2	39	387	26	408	5.0e-20	92.3	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
649914753	748	27.48	47	747	2	686	3.0e-110	393	COG3345	Alpha-galactosidase	687
649914755	439	22.81	36	411	3	341	2.0e-33	136	COG0673	Predicted dehydrogenase	342
649914756	514	33.6	37	504	1	486	1.0e-103	370	COG5476	Microcystin degradation protein MlrC, contains DUF1485 domain	488
649914757	441	23.36	13	434	15	440	4.0e-35	143	COG2271	Sugar phosphate permease	448
649914758	266	27.82	16	259	1	236	4.0e-41	162	COG0363	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase	238
649914759	365	35.59	11	339	3	332	4.0e-58	218	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
649914760	417	22.63	9	403	30	428	2.0e-21	97.2	COG2271	Sugar phosphate permease	448
649914761	538	24.62	14	537	127	773	7.0e-55	208	COG4993	Glucose dehydrogenase	773
649914762	278	23.2	30	149	29	148	8.0e-07	48	COG2010	Cytochrome c, mono- and diheme variants	150
649914766	265	39.26	10	251	3	244	3.0e-47	181	COG1414	DNA-binding transcriptional regulator, IclR family	246
649914767	345	22.71	16	326	7	289	8.0e-11	61.8	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
649914768	343	22.4	35	325	3	310	2.0e-11	63.4	COG0451	Nucleoside-diphosphate-sugar epimerase	314
649914770	530	22.47	14	493	1	484	2.0e-34	141	COG0591	Na+/proline symporter	493
649914771	257	25.81	13	255	1	237	5.0e-38	151	COG0363	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase	238
649914772	307	21.14	65	288	13	257	4.0e-17	82.6	COG1082	Sugar phosphate isomerase/epimerase	274
649914773	310	24.6	52	284	18	252	2.0e-17	83.3	COG1082	Sugar phosphate isomerase/epimerase	274
649914774	361	36.94	10	332	1	333	2.0e-62	233	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
649914776	392	42.08	21	379	4	351	2.0e-94	339	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
649914779	275	35.29	149	267	5	123	3.0e-23	102	COG3324	Predicted enzyme related to lactoylglutathione lyase	127
649914780	254	32.49	12	232	2	236	1.0e-54	206	COG4312	Predicted dithiol-disulfide oxidoreductase, DUF899 family	247
649914781	611	24.81	124	570	3	495	2.0e-46	180	COG0366	Glycosidase	505
649914783	739	29.93	9	155	8	148	1.0e-20	95.4	COG3710	DNA-binding winged helix-turn-helix (wHTH) domain	148
649914784	834	37.39	109	782	119	745	0.0e+00	481	COG1501	Alpha-glucosidase, glycosyl hydrolase family GH31	772
649914785	460	27.11	53	449	92	515	5.0e-36	145	COG5434	Polygalacturonase	542
649914786	353	27.86	28	336	82	404	4.0e-34	139	COG4677	Pectin methylesterase and related acyl-CoA thioesterases	405
649914789	397	21.52	90	383	31	321	8.0e-16	78.7	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
649914792	126	35.85	1	104	1	104	8.0e-20	89.2	COG3254	L-rhamnose mutarotase	105
649914793	478	21.58	8	478	6	474	5.0e-100	358	COG2160	L-arabinose isomerase	497
649914795	500	27.93	51	493	1	467	7.0e-54	205	COG3119	Arylsulfatase A or related enzyme	475
649914798	261	32.94	8	260	1	244	2.0e-40	159	COG3279	DNA-binding response regulator, LytR/AlgR family	244
649914799	406	33.91	12	405	30	396	2.0e-57	216	COG2133	Glucose/arabinose dehydrogenase, beta-propeller fold	399
649914801	466	31.89	146	466	20	331	3.0e-35	143	COG0642	Signal transduction histidine kinase	336
649914802	233	43.04	7	231	2	228	3.0e-52	198	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
649914804	438	26.11	36	437	43	445	8.0e-28	118	COG1538	Outer membrane protein TolC	457
649914805	405	30.36	8	397	12	371	4.0e-20	92.9	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
649914806	1054	29.34	1	1048	2	1008	0.0e+00	642	COG0841	Multidrug efflux pump subunit AcrB	1009
649914807	443	57.76	1	438	1	438	0.0e+00	663	COG2115	Xylose isomerase	438
649914808	142	47.62	49	130	14	97	1.0e-16	79.2	COG3695	Alkylated DNA nucleotide flippase Atl1, participates in nucleotide excision repair, Ada-like DNA-binding domain	103
649914812	197	34.81	36	193	21	175	2.0e-27	115	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
649914813	931	34.15	86	362	2	282	2.0e-35	144	COG0515	Serine/threonine protein kinase	384
649914814	206	30.11	31	202	10	178	4.0e-08	51.6	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
649914815	297	36.65	48	294	1	250	4.0e-51	195	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
649914818	413	24.07	61	354	25	274	2.0e-30	127	COG1446	Isoaspartyl peptidase or L-asparaginase, Ntn-hydrolase superfamily	307
649914820	315	34.6	1	308	3	316	2.0e-64	239	COG2423	Ornithine cyclodeaminase/archaeal alanine dehydrogenase, mu-crystallin family	330
649914821	327	42.43	18	318	11	314	6.0e-74	270	COG1171	Threonine dehydratase	347
649914822	314	47.6	1	311	1	313	1.0e-83	303	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
649914823	276	48.55	1	274	13	288	2.0e-64	238	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
649914824	548	50.19	10	537	4	536	0.0e+00	578	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
649914825	484	23.4	19	297	41	367	1.0e-23	104	COG1680	CubicO group peptidase, beta-lactamase class C family	390
649914826	388	52.85	1	384	1	378	2.0e-117	416	COG2828	2-Methylaconitate cis-trans-isomerase PrpF (2-methyl citrate pathway)	378
649914827	944	56.84	7	942	1	861	0.0e+00	1156	COG1048	Aconitase A	861
649914828	544	28.31	33	541	21	550	7.0e-67	248	COG0747	ABC-type transport system, periplasmic component	556
649914830	250	25	56	250	1	215	7.0e-15	74.6	COG2755	Lysophospholipase L1 or related esterase	216
649914831	894	54.23	6	888	1	861	0.0e+00	1017	COG1048	Aconitase A	861
649914832	315	27.23	87	307	10	229	3.0e-19	89.4	COG1802	DNA-binding transcriptional regulator, GntR family	230
649914833	453	19.95	60	445	38	393	4.0e-14	72.9	COG2814	Predicted arabinose efflux permease, MFS family	394
649914834	167	43.2	1	164	6	174	8.0e-41	159	COG0684	Regulator of RNase E activity RraA	210
649914835	409	25.79	24	403	6	394	4.0e-28	119	COG3182	Uncharacterized iron-regulated membrane protein	442
649914837	366	29.73	49	365	61	390	6.0e-55	208	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
649914838	457	26.68	12	457	1	449	8.0e-55	208	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
649914840	259	27.48	1	251	2	259	1.0e-31	129	COG0345	Pyrroline-5-carboxylate reductase	266
649914843	385	38.58	5	383	1	377	9.0e-94	337	COG1454	Alcohol dehydrogenase, class IV	377
649914844	274	31.15	10	250	12	252	2.0e-35	143	COG3836	2-keto-3-deoxy-L-rhamnonate aldolase RhmA	255
649914845	522	24.8	1	486	1	487	1.0e-39	158	COG0591	Na+/proline symporter	493
649914846	330	41.46	7	320	4	329	4.0e-85	308	COG1995	4-hydroxy-L-threonine phosphate dehydrogenase PdxA	332
649914847	356	22.38	12	348	5	413	8.0e-25	108	COG3395	Uncharacterized conserved protein YgbK, DUF1537 family	413
649914848	412	26.6	51	402	24	379	3.0e-27	116	COG4692	Predicted neuraminidase (sialidase)	381
649914849	292	35.54	40	279	1	242	6.0e-42	164	COG1414	DNA-binding transcriptional regulator, IclR family	246
649914851	289	32.77	171	289	4	122	1.0e-23	103	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
649914852	551	34.91	25	542	1	541	1.0e-102	367	COG2303	Choline dehydrogenase or related flavoprotein	542
649914853	469	32.49	20	455	20	447	1.0e-47	184	COG1538	Outer membrane protein TolC	457
649914855	276	34.04	1	234	3	236	1.0e-37	149	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
649914857	785	34.88	2	130	4	130	3.0e-22	100	COG3710	DNA-binding winged helix-turn-helix (wHTH) domain	148
649914858	508	28.73	101	508	80	481	6.0e-34	139	COG3488	Uncharacterized conserved protein with two CxxC motifs, DUF1111 family	481
649914860	234	22.83	40	223	8	189	2.0e-09	56.2	COG1309	DNA-binding transcriptional regulator, AcrR family	201
649914863	565	34.47	227	547	3	300	1.0e-53	204	COG0492	Thioredoxin reductase	305
649914864	277	23.24	19	259	2	227	1.0e-18	87.1	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
649914869	445	22.65	29	445	41	445	2.0e-31	130	COG1524	Predicted pyrophosphatase or phosphodiesterase, AlkP superfamily	450
649914871	266	34.31	23	261	4	236	2.0e-37	149	COG2188	DNA-binding transcriptional regulator, GntR family	236
649914872	305	24.73	27	288	35	304	2.0e-16	79.9	COG0524	Sugar or nucleoside kinase, ribokinase family	311
649914875	854	14.07	101	854	41	768	1.0e-04	42.2	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
649914876	472	34.41	155	463	34	334	1.0e-39	157	COG0642	Signal transduction histidine kinase	336
649914877	225	44.3	1	222	1	227	3.0e-54	204	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
649914878	468	47.65	1	467	4	456	0.0e+00	474	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
649914879	555	27.04	232	542	32	335	3.0e-35	143	COG0642	Signal transduction histidine kinase	336
649914882	427	17.46	1	401	1	385	3.0e-09	56.8	COG2814	Predicted arabinose efflux permease, MFS family	394
649914884	434	28.54	13	426	8	423	5.0e-51	195	COG1055	Na+/H+ antiporter NhaD or related arsenite permease	424
649914885	150	38.19	7	150	5	147	9.0e-16	76.4	COG3238	Uncharacterized membrane protein YdcZ, DUF606 family	150
649914889	232	36.12	6	229	1	227	1.0e-27	116	COG1814	Predicted Fe2+/Mn2+ transporter, VIT1/CCC1 family	229
649914890	489	29.48	146	471	4	328	1.0e-36	148	COG0642	Signal transduction histidine kinase	336
649914891	224	45.41	1	224	1	228	2.0e-55	209	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
649914897	376	24.03	1	300	2	300	5.0e-19	89	COG0644	Dehydrogenase (flavoprotein)	396
649914900	216	29.08	12	205	15	209	6.0e-23	101	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
649914902	172	37.5	33	154	13	134	2.0e-20	92	COG3727	G:T-mismatch repair DNA endonuclease, very short patch repair protein	150
649914903	169	44.31	3	157	1	167	4.0e-40	157	COG0350	O6-methylguanine-DNA--protein-cysteine methyltransferase	168
649914904	224	41.06	25	220	71	276	2.0e-46	179	COG0122	3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase	285
649914905	359	50.27	10	194	2	184	2.0e-57	216	COG2169	Methylphosphotriester-DNA--protein-cysteine methyltransferase (N-terminal fragment of Ada), contains Zn-binding and two AraC-type DNA-binding domains	187
649914906	257	73.21	33	256	12	235	4.0e-97	347	COG3826	Uncharacterized protein	236
649914907	217	40.7	14	211	8	194	2.0e-41	162	COG3145	Alkylated DNA repair dioxygenase AlkB	194
649914909	254	23.66	52	237	11	185	5.0e-20	91.8	COG3548	Uncharacterized membrane protein	197
649914910	271	31.45	147	269	1	124	7.0e-18	84.5	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
649914911	391	25.83	18	369	3	358	5.0e-42	165	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
649914912	375	25.26	52	339	35	290	8.0e-17	81.9	COG3547	Transposase	303
649914913	1105	19.44	155	395	12	250	1.0e-06	49.3	COG1305	Transglutaminase-like enzyme, putative cysteine protease	319
649914915	206	37.1	116	177	8	69	5.0e-09	54.6	COG2442	Uncharacterized conserved protein, DUF433 family	79
649914917	124	36.05	32	117	22	106	1.0e-13	68.5	COG1733	DNA-binding transcriptional regulator, HxlR family	120
649914919	448	25.24	39	448	44	451	1.0e-27	117	COG1538	Outer membrane protein TolC	457
649914922	415	31.86	10	415	7	341	2.0e-53	203	COG1566	Multidrug resistance efflux pump	352
649914923	304	23.83	5	301	2	297	1.0e-22	100	COG0583	DNA-binding transcriptional regulator, LysR family	297
649914924	244	36.84	11	238	18	262	1.0e-46	180	COG2375	NADPH-dependent ferric siderophore reductase, contains FAD-binding and SIP domains	265
649914925	260	37.5	146	256	7	118	1.0e-15	76.8	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
649914928	849	31.36	153	835	79	745	4.0e-92	333	COG4774	Outer membrane receptor for monomeric catechols	750
649914929	227	56.14	1	227	3	229	4.0e-74	271	COG3128	Predicted 2-oxoglutarate- and Fe(II)-dependent dioxygenase YbiX	229
649914931	533	19.69	1	420	1	439	1.0e-17	84.6	COG3182	Uncharacterized iron-regulated membrane protein	442
649914934	682	25.9	393	663	68	333	1.0e-29	125	COG0642	Signal transduction histidine kinase	336
649914935	230	29.7	3	163	2	161	4.0e-14	71.6	COG3666	Transposase	161
649914937	550	29.58	35	244	7	214	7.0e-22	99.2	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
649914950	365	25.26	130	308	2	188	3.0e-14	73.1	COG2856	Zn-dependent peptidase ImmA, M78 family	213
649914960	285	32.79	162	276	1	122	2.0e-15	76.3	COG0629	Single-stranded DNA-binding protein	167
649914961	322	38.64	13	318	49	348	1.0e-58	220	COG4962	Pilus assembly protein, ATPase of CpaF family	355
649914962	268	20.18	33	249	39	234	2.0e-05	43	COG3736	Type IV secretory pathway, component VirB8	239
649914968	423	23.66	142	413	84	353	6.0e-22	99	COG2948	Type IV secretory pathway, VirB10 components	360
649914970	789	22.25	25	749	21	749	1.0e-48	189	COG3451	Type IV secretory pathway, VirB4 component	796
649914973	319	29.44	6	251	2	242	2.0e-20	93.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
649914975	432	25.98	122	365	49	278	2.0e-06	47.5	COG4974	Site-specific recombinase XerD	300
649914977	264	31.89	78	262	1	177	8.0e-28	117	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
649914982	375	25.26	52	339	35	290	8.0e-17	81.9	COG3547	Transposase	303
649914984	107	47.31	1	93	2	94	3.0e-27	113	COG0776	Bacterial nucleoid DNA-binding protein	94
649914985	154	44.53	21	147	9	134	4.0e-27	113	COG0824	Acyl-CoA thioesterase FadM	137
649914986	212	32.24	11	185	7	172	3.0e-27	114	COG1335	Nicotinamidase-related amidase	205
649914987	178	31.25	65	159	1	96	8.0e-09	53.5	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
649914988	289	49.41	17	271	5	245	6.0e-74	271	COG0020	Undecaprenyl pyrophosphate synthase	245
649914989	280	32.84	2	271	4	263	1.0e-29	123	COG0575	CDP-diglyceride synthetase	265
649914991	385	55.32	1	383	1	382	0.0e+00	484	COG0743	1-deoxy-D-xylulose 5-phosphate reductoisomerase	385
649914993	461	25	58	354	12	317	8.0e-29	121	COG1921	Seryl-tRNA(Sec) selenium transferase	395
649914994	190	21.43	55	180	24	128	3.0e-10	58.4	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
649914996	539	33.8	12	434	9	423	2.0e-60	227	COG0025	NhaP-type Na+/H+ or K+/H+ antiporter	429
649914997	836	32.09	39	822	6	755	3.0e-109	389	COG2366	Acyl-homoserine lactone (AHL) acylase PvdQ	768
649914999	309	37.13	6	309	1	322	2.0e-61	229	COG0142	Geranylgeranyl pyrophosphate synthase	322
649915000	128	25.89	4	115	13	111	5.0e-09	53.4	COG2151	Metal-sulfur cluster biosynthetic enzyme	111
649915002	536	27.54	46	513	39	514	4.0e-54	206	COG4365	Uncharacterized protein YllA, UPF0747 family	537
649915003	207	26.83	54	202	2	158	2.0e-09	56.1	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
649915004	71	55.38	5	68	3	67	1.0e-19	87.9	COG1278	Cold shock protein, CspA family	67
649915005	580	40.79	1	329	3	326	4.0e-74	272	COG1796	DNA polymerase/3'-5' exonuclease PolX	326
649915008	306	28.01	1	306	2	383	2.0e-28	120	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
649915009	377	49.33	9	377	19	390	1.0e-115	409	COG0372	Citrate synthase	390
649915010	248	35.18	3	246	2	251	5.0e-44	171	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
649915011	220	25.25	31	219	24	222	9.0e-11	60.5	COG1418	HD superfamily phosphodieaserase, includes HD domain of RNase Y	222
649915012	794	20.84	56	790	1	719	2.0e-36	148	COG4773	Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid	719
649915013	251	38.67	8	248	4	250	4.0e-36	144	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
649915015	189	33.54	29	189	14	177	2.0e-19	89	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
649915016	928	17.13	113	888	41	758	5.0e-22	100	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
649915017	298	27.68	52	274	27	237	5.0e-17	81.9	COG0327	Putative GTP cyclohydrolase 1 type 2, NIF3 family	250
649915018	303	36.36	69	300	2	233	3.0e-42	165	COG0412	Dienelactone hydrolase	236
649915019	140	55	10	129	13	132	2.0e-41	161	COG5649	Uncharacterized protein	132
649915020	307	29.35	1	305	1	297	3.0e-31	129	COG0583	DNA-binding transcriptional regulator, LysR family	297
649915021	246	44	3	243	2	249	2.0e-42	166	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
649915022	371	52.23	3	370	2	382	4.0e-128	451	COG1104	Cysteine sulfinate desulfinase/cysteine desulfurase or related enzyme	386
649915023	389	43.94	20	388	6	354	5.0e-115	407	COG0482	tRNA U34 2-thiouridine synthase MnmA/TrmU, contains the PP-loop ATPase domain	356
649915025	130	29.76	15	98	12	95	1.0e-04	38.8	COG4980	Gas vesicle protein	115
649915026	421	28.61	1	421	2	403	4.0e-45	176	COG1819	UDP:flavonoid glycosyltransferase YjiC, YdhE family	406
649915031	590	31.99	7	572	1	502	5.0e-98	352	COG1543	Predicted glycosyl hydrolase, contains GH57 and DUF1957 domains	504
649915034	183	33.93	1	166	2	162	1.0e-19	89.6	COG2062	Phosphohistidine phosphatase SixA	163
649915035	532	33.4	1	478	2	446	2.0e-85	310	COG0248	Exopolyphosphatase/pppGpp-phosphohydrolase	492
649915038	395	23.24	1	368	9	369	9.0e-24	105	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
649915039	146	37.89	11	104	1	94	1.0e-13	69	COG0789	DNA-binding transcriptional regulator, MerR family	124
649915040	348	36.28	37	251	4	213	5.0e-45	175	COG0300	Short-chain dehydrogenase	265
649915041	406	41.16	6	394	3	351	2.0e-95	342	COG0484	DnaJ-class molecular chaperone with C-terminal Zn finger domain	371
649915043	305	26.97	1	294	1	272	2.0e-46	179	COG0266	Formamidopyrimidine-DNA glycosylase	273
649915044	104	44.57	13	104	7	97	8.0e-21	91.9	COG3093	Plasmid maintenance system antidote protein VapI, contains XRE-type HTH domain	104
649915045	92	44.68	1	92	1	94	2.0e-23	101	COG3549	Plasmid maintenance system killer protein	94
649915047	638	60.07	1	600	4	579	0.0e+00	670	COG0443	Molecular chaperone DnaK (HSP70)	579
649915048	358	22.41	4	356	13	333	9.0e-12	64.7	COG4447	Uncharacterized protein related to plant photosystem II stability/assembly factor	339
649915052	223	22.62	19	186	21	182	1.0e-04	39.9	COG3166	Tfp pilus assembly protein PilN	206
649915054	544	43.79	33	539	5	499	0.0e+00	504	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
649915055	399	37.56	1	393	1	393	3.0e-78	285	COG1459	Type II secretory pathway, component PulF	397
649915056	126	47.71	18	126	2	110	4.0e-32	129	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
649915058	412	38.27	46	402	5	311	8.0e-69	254	COG2355	Zn-dependent dipeptidase, microsomal dipeptidase homolog	313
649915059	381	21.33	14	374	15	373	3.0e-19	89.8	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
649915060	251	63.09	15	246	4	236	4.0e-90	324	COG0528	Uridylate kinase	238
649915062	308	56.52	1	253	1	252	2.0e-95	342	COG0052	Ribosomal protein S2	252
649915063	131	57.03	4	131	3	130	2.0e-39	154	COG0103	Ribosomal protein S9	130
649915064	144	51.75	1	142	1	143	5.0e-45	173	COG0102	Ribosomal protein L13	148
649915065	510	15.97	42	510	33	498	1.0e-07	51.7	COG1807	4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferase of PMT family	535
649915066	368	22.67	16	368	26	408	8.0e-21	95	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
649915067	300	24.37	1	293	11	319	2.0e-27	116	COG1305	Transglutaminase-like enzyme, putative cysteine protease	319
649915068	391	69.97	4	379	2	383	0.0e+00	662	COG0192	S-adenosylmethionine synthetase	388
649915069	330	29.95	25	230	1	201	6.0e-25	108	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
649915070	423	25.23	1	423	2	406	7.0e-40	158	COG1819	UDP:flavonoid glycosyltransferase YjiC, YdhE family	406
649915072	357	40.64	11	194	3	184	4.0e-41	162	COG2169	Methylphosphotriester-DNA--protein-cysteine methyltransferase (N-terminal fragment of Ada), contains Zn-binding and two AraC-type DNA-binding domains	187
649915073	476	53.8	9	468	2	420	0.0e+00	626	COG0499	S-adenosylhomocysteine hydrolase	420
649915076	113	53.4	6	108	10	110	5.0e-35	139	COG0139	Phosphoribosyl-AMP cyclohydrolase	111
649915077	291	38.18	3	290	1	289	2.0e-60	225	COG0040	ATP phosphoribosyltransferase	290
649915078	440	46.96	10	426	5	421	7.0e-129	454	COG0141	Histidinol dehydrogenase	425
649915079	372	36.34	5	350	2	354	4.0e-74	271	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
649915080	221	51.53	26	221	2	195	3.0e-67	248	COG0131	Imidazoleglycerol phosphate dehydratase HisB	195
649915081	202	45.37	1	202	3	202	8.0e-63	233	COG0118	Imidazoleglycerol phosphate synthase glutamine amidotransferase subunit HisH	204
649915082	258	60.31	1	257	1	256	1.0e-99	355	COG0107	Imidazole glycerol phosphate synthase subunit HisF	256
649915083	233	32.22	1	229	3	227	4.0e-36	144	COG0106	Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase	241
649915085	342	24.39	89	287	65	255	2.0e-05	44.1	COG1240	Mg-chelatase subunit ChlD	261
649915087	309	19.05	205	309	37	139	1.0e-03	37.5	COG2510	Uncharacterized membrane protein	140
649915088	273	33.74	16	260	26	270	4.0e-67	248	COG2326	Polyphosphate kinase 2, PPK2 family	270
649915091	421	49.75	1	407	3	390	2.0e-130	459	COG0448	ADP-glucose pyrophosphorylase	393
649915095	375	45.09	4	375	3	375	3.0e-108	385	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
649915096	129	51.16	1	126	3	131	2.0e-34	137	COG0509	Glycine cleavage system H protein (lipoate-binding)	131
649915098	443	43.93	1	443	10	446	2.0e-130	459	COG0403	Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain	450
649915100	515	49.39	17	499	2	485	0.0e+00	623	COG1003	Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain	496
649915107	370	22.19	11	370	10	364	1.0e-26	114	COG0592	DNA polymerase III sliding clamp (beta) subunit, PCNA homolog	364
649915118	1627	21.27	753	1465	1	661	1.0e-18	89.9	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
649915121	660	30.53	12	635	4	603	4.0e-96	346	COG5525	Phage terminase, large subunit GpA	611
649915122	305	24.23	9	279	20	283	2.0e-04	40.2	COG4974	Site-specific recombinase XerD	300
649915127	536	41.67	1	532	3	528	0.0e+00	527	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
649915128	335	43.64	1	324	1	306	6.0e-78	284	COG3684	Tagatose-1,6-bisphosphate aldolase	306
649915129	286	34.47	33	232	5	210	2.0e-28	119	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
649915130	140	39.34	14	135	2	123	7.0e-26	109	COG1725	DNA-binding transcriptional regulator YhcF, GntR family	125
649915131	272	19.23	42	272	19	241	4.0e-09	55.5	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
649915132	551	65.23	227	551	1	315	0.0e+00	532	COG0519	GMP synthase, PP-ATPase domain/subunit	315
649915135	846	51.07	14	845	4	814	0.0e+00	980	COG0495	Leucyl-tRNA synthetase	814
649915137	291	36.3	8	275	1	263	1.0e-62	233	COG0648	Endonuclease IV	280
649915139	94	39.78	1	88	27	119	7.0e-24	101	COG2343	Uncharacterized conserved protein, DUF427 family	132
649915140	951	40.62	782	902	13	140	2.0e-18	89	COG0551	ssDNA-binding Zn-finger and Zn-ribbon domains of topoisomerase 1	140
649915140	951	47.37	3	602	1	562	0.0e+00	602	COG0550	DNA topoisomerase IA	570
649915141	410	39.11	28	408	3	349	6.0e-85	308	COG0758	Predicted Rossmann fold nucleotide-binding protein DprA/Smf involved in DNA uptake	350
649915142	227	22.44	22	218	8	206	3.0e-09	55.3	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
649915143	338	52	12	336	3	322	2.0e-106	379	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
649915146	560	34.58	56	559	1	436	8.0e-113	401	COG0621	tRNA A37 methylthiotransferase MiaB	437
649915148	74	43.64	1	53	2	56	3.0e-08	50.4	COG3024	Endogenous inhibitor of DNA gyrase, YacG/DUF329 family	65
649915149	175	35.46	30	169	22	159	2.0e-16	78.8	COG1267	Phosphatidylglycerophosphatase A	160
649915151	214	26.14	27	113	1	88	9.0e-06	43.9	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
649915153	420	35.09	1	265	2	255	7.0e-47	181	COG1058	Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA	255
649915154	205	43.35	1	202	2	200	3.0e-40	158	COG0344	Phospholipid biosynthesis protein PlsY, probable glycerol-3-phosphate acyltransferase	200
649915155	330	50.76	1	330	1	329	2.0e-105	375	COG0240	Glycerol-3-phosphate dehydrogenase	329
649915156	376	48.05	50	375	8	340	3.0e-98	352	COG0552	Signal recognition particle GTPase	340
649915157	416	27.15	49	333	12	296	2.0e-27	117	COG1921	Seryl-tRNA(Sec) selenium transferase	395
649915158	518	29.5	48	516	5	450	2.0e-57	217	COG1231	Monoamine oxidase	450
649915159	397	56.25	5	148	2	145	7.0e-52	198	COG0117	Pyrimidine deaminase domain of riboflavin biosynthesis protein RibD	146
649915160	217	40.19	1	209	1	202	4.0e-51	194	COG0307	Riboflavin synthase alpha chain	204
649915161	206	42.25	8	187	4	189	3.0e-51	194	COG1435	Thymidine kinase	201
649915162	125	33.68	39	122	31	125	5.0e-06	43.4	COG3324	Predicted enzyme related to lactoylglutathione lyase	127
649915163	109	39.25	5	109	2	108	2.0e-21	94.5	COG0393	Uncharacterized conserved protein YbjQ, UPF0145 family	108
649915164	339	51.53	8	333	12	329	1.0e-94	339	COG0547	Anthranilate phosphoribosyltransferase	338
649915165	392	54.59	1	390	1	386	0.0e+00	488	COG0045	Succinyl-CoA synthetase, beta subunit	387
649915166	291	66.67	1	290	1	291	2.0e-114	405	COG0074	Succinyl-CoA synthetase, alpha subunit	293
649915167	138	52.24	1	134	1	134	4.0e-45	173	COG0105	Nucleoside diphosphate kinase	135
649915171	269	29.17	76	267	1	181	4.0e-33	135	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
649915172	176	35.75	5	173	6	178	2.0e-25	108	COG2032	Cu/Zn superoxide dismutase	179
649915173	399	26.42	190	390	7	201	7.0e-15	75.3	COG2755	Lysophospholipase L1 or related esterase	216
649915177	203	36.72	23	191	1	158	8.0e-28	116	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
649915184	313	38.14	7	292	2	283	2.0e-62	233	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
649915185	344	30.52	1	338	10	375	4.0e-45	175	COG1680	CubicO group peptidase, beta-lactamase class C family	390
649915187	445	45.21	10	410	4	400	9.0e-106	377	COG1252	NADH dehydrogenase, FAD-containing subunit	405
649915188	523	27.01	53	514	2	484	5.0e-42	165	COG0591	Na+/proline symporter	493
649915189	727	31.88	11	727	10	726	1.0e-120	427	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
649915190	324	33.1	36	317	19	301	7.0e-40	158	COG1295	Uncharacterized membrane protein, BrkB/YihY/UPF0761 family (not an RNase)	303
649915191	307	32.21	45	306	10	258	4.0e-30	125	COG2220	L-ascorbate metabolism protein UlaG, beta-lactamase superfamily	258
649915192	359	22.05	12	310	4	308	2.0e-12	67.3	COG0451	Nucleoside-diphosphate-sugar epimerase	314
649915195	104	43.82	9	95	6	94	4.0e-15	73	COG1872	Uncharacterized conserved protein YggU, UPF0235/DUF167 family	102
649915196	235	44.87	1	234	1	226	3.0e-66	245	COG0325	Uncharacterized pyridoxal phosphate-containing protein, affects Ilv metabolism, UPF0001 family	228
649915199	318	49.68	6	318	2	305	4.0e-87	314	COG0492	Thioredoxin reductase	305
649915200	155	25.34	17	152	18	163	4.0e-13	67.6	COG3477	Uncharacterized membrane protein YagU, involved in acid resistance, DUF1440 family	176
649915201	363	25.5	41	363	13	355	3.0e-35	143	COG4225	Rhamnogalacturonyl hydrolase YesR	357
649915202	97	28.57	6	96	6	93	2.0e-09	54.5	COG1550	Uncharacterized conserved protein YlxP, DUF503 family	95
649915203	178	36.52	5	118	1	115	2.0e-18	85.2	COG0858	Ribosome-binding factor A	118
649915204	618	26.67	27	500	2	422	6.0e-32	132	COG1807	4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferase of PMT family	535
649915210	397	24.7	1	397	9	383	4.0e-28	119	COG0006	Xaa-Pro aminopeptidase	384
649915211	507	27.08	256	495	1	169	3.0e-30	126	COG0516	IMP dehydrogenase/GMP reductase	170
649915212	254	34.07	24	244	17	240	2.0e-47	182	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
649915214	195	31.22	6	194	8	152	3.0e-23	101	COG0779	Ribosome maturation factor RimP	153
649915215	562	47.96	159	354	1	190	6.0e-42	165	COG0195	Transcription antitermination factor NusA, contains S1 and KH domains	190
649915216	1088	56.97	541	1048	3	507	0.0e+00	647	COG0532	Translation initiation factor IF-2, a GTPase	509
649915223	415	17.78	124	414	7	314	2.0e-06	47.6	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
649915224	195	48.15	1	162	4	165	6.0e-31	127	COG3685	Ferritin-like metal-binding protein YciE	167
649915227	158	54.31	1	116	1	116	3.0e-36	144	COG0203	Ribosomal protein L17	116
649915228	366	47.02	6	324	1	315	1.0e-88	320	COG0202	DNA-directed RNA polymerase, alpha subunit/40 kD subunit	317
649915229	209	51.9	1	209	1	205	7.0e-57	213	COG0522	Ribosomal protein S4 or related protein	205
649915230	141	62.5	14	141	2	129	1.0e-43	168	COG0100	Ribosomal protein S11	129
649915231	126	61.48	1	122	1	121	5.0e-37	146	COG0099	Ribosomal protein S13	121
649915232	37	73.68	1	37	1	38	2.0e-03	34.4	COG0257	Ribosomal protein L36	38
649915233	72	65.28	1	72	1	72	1.0e-23	101	COG0361	Translation initiation factor IF-1	75
649915234	249	52.99	1	249	1	251	4.0e-89	320	COG0024	Methionine aminopeptidase	255
649915235	236	38.86	21	231	3	178	4.0e-40	158	COG0563	Adenylate kinase or related kinase	178
649915236	465	46.27	1	452	6	430	2.0e-114	406	COG0201	Preprotein translocase subunit SecY	436
649915237	162	49.67	5	151	3	152	2.0e-30	124	COG0200	Ribosomal protein L15	152
649915238	62	40	8	62	1	55	1.0e-08	51.3	COG1841	Ribosomal protein L30/L7E	55
649915239	168	59.15	6	168	16	178	6.0e-50	190	COG0098	Ribosomal protein S5	181
649915240	121	55.65	1	121	2	125	2.0e-32	131	COG0256	Ribosomal protein L18	125
649915241	179	45.56	1	178	1	178	6.0e-46	176	COG0097	Ribosomal protein L6P/L9E	178
649915242	132	51.52	1	132	1	132	6.0e-44	169	COG0096	Ribosomal protein S8	132
649915243	61	54.1	1	61	1	61	7.0e-15	72.2	COG0199	Ribosomal protein S14	61
649915244	181	58.43	2	179	1	178	7.0e-67	246	COG0094	Ribosomal protein L5	180
649915245	107	54.81	1	102	3	103	2.0e-16	77.3	COG0198	Ribosomal protein L24	104
649915246	123	61.98	3	123	2	122	2.0e-41	161	COG0093	Ribosomal protein L14	122
649915247	115	52.94	17	101	1	85	2.0e-21	94.5	COG0186	Ribosomal protein S17	87
649915248	83	34.92	4	66	6	68	3.0e-04	37.2	COG0255	Ribosomal protein L29	69
649915249	143	53.79	1	143	2	146	1.0e-44	171	COG0197	Ribosomal protein L16/L10AE	146
649915250	222	55.66	12	221	1	212	9.0e-70	256	COG0092	Ribosomal protein S3	233
649915251	174	42.74	12	128	7	118	2.0e-20	91.8	COG0091	Ribosomal protein L22	120
649915252	94	65.59	1	93	1	93	5.0e-35	139	COG0185	Ribosomal protein S19	93
649915253	274	58.55	1	274	1	275	5.0e-107	380	COG0090	Ribosomal protein L2	275
649915254	97	49.43	4	89	1	87	4.0e-20	89.5	COG0089	Ribosomal protein L23	94
649915255	226	46.48	1	210	1	212	1.0e-49	190	COG0088	Ribosomal protein L4	214
649915256	242	43.98	3	216	1	214	2.0e-59	221	COG0087	Ribosomal protein L3	218
649915257	106	71.72	4	102	3	101	4.0e-37	146	COG0051	Ribosomal protein S10	104
649915258	395	75.19	1	395	1	394	0.0e+00	678	COG0050	Translation elongation factor EF-Tu, a GTPase	394
649915259	696	66.33	1	695	1	695	0.0e+00	983	COG0480	Translation elongation factor EF-G, a GTPase	697
649915260	157	57.05	2	150	1	148	4.0e-50	190	COG0049	Ribosomal protein S7	148
649915261	127	78.05	1	123	7	129	4.0e-48	183	COG0048	Ribosomal protein S12	129
649915264	196	20.83	12	167	9	176	1.0e-07	50	COG1309	DNA-binding transcriptional regulator, AcrR family	201
649915265	205	45.08	1	192	1	188	7.0e-51	193	COG1182	FMN-dependent NADH-azoreductase	202
649915266	127	20	4	120	2	136	6.0e-06	43.3	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
649915267	690	28.27	25	679	2	617	4.0e-73	269	COG1506	Dipeptidyl aminopeptidase/acylaminoacyl peptidase	620
649915271	179	20.14	37	169	23	148	7.0e-04	37.3	COG2318	Uncharacterized damage-inducible protein DinB (forms a four-helix bundle)	172
649915272	280	26.81	32	263	8	228	8.0e-16	77.8	COG0705	Membrane associated serine protease, rhomboid family	228
649915275	152	37.5	1	150	10	158	5.0e-22	97.1	COG2030	Acyl dehydratase	159
649915276	241	39.27	3	239	14	251	1.0e-50	193	COG0631	Serine/threonine protein phosphatase PrpC	262
649915277	278	26.22	4	278	12	268	1.0e-21	96.9	COG0863	DNA modification methylase	302
649915278	247	28.85	1	244	1	259	3.0e-20	91.9	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
649915279	311	16.97	36	293	1	237	8.0e-08	51.5	COG1409	3',5'-cyclic AMP phosphodiesterase CpdA	301
649915280	143	30.08	12	143	4	135	6.0e-18	83.4	COG0355	FoF1-type ATP synthase, epsilon subunit	135
649915281	480	68.83	5	479	3	468	0.0e+00	768	COG0055	FoF1-type ATP synthase, beta subunit	468
649915282	363	37.33	6	363	2	286	2.0e-71	262	COG0224	FoF1-type ATP synthase, gamma subunit	287
649915284	515	69.46	3	503	2	502	0.0e+00	794	COG0056	FoF1-type ATP synthase, alpha subunit	504
649915285	181	34.09	1	176	4	177	6.0e-27	113	COG0712	FoF1-type ATP synthase, delta subunit	178
649915286	238	29.38	74	231	1	160	1.0e-08	54.1	COG0711	FoF1-type ATP synthase, membrane subunit b or b'	161
649915287	155	25.2	18	144	12	138	4.0e-07	47.6	COG0711	FoF1-type ATP synthase, membrane subunit b or b'	161
649915288	500	51.87	74	472	17	411	4.0e-113	402	COG2262	50S ribosomal subunit-associated GTPase HflX	411
649915289	95	51.43	4	73	2	71	2.0e-20	90.8	COG1923	sRNA-binding regulator protein Hfq	77
649915290	382	38.02	6	380	1	370	5.0e-94	338	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
649915291	233	25	7	233	1	227	1.0e-15	77.3	COG1814	Predicted Fe2+/Mn2+ transporter, VIT1/CCC1 family	229
649915293	194	22.53	3	183	9	185	8.0e-10	57.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
649915295	494	50.41	15	491	5	477	0.0e+00	512	COG0469	Pyruvate kinase	477
649915296	291	25.63	10	285	14	287	3.0e-30	125	COG1295	Uncharacterized membrane protein, BrkB/YihY/UPF0761 family (not an RNase)	303
649915298	308	31.25	62	298	11	248	7.0e-32	131	COG1354	Chromatin segregation and condensation protein Rec8/ScpA/Scc1, kleisin family	248
649915300	360	43.57	5	341	3	314	2.0e-100	359	COG0180	Tryptophanyl-tRNA synthetase	314
649915301	230	32.37	5	206	13	192	2.0e-11	63.1	COG1994	Zn-dependent protease (includes SpoIVFB)	230
649915303	237	25.51	2	237	4	242	2.0e-16	80	COG2968	Uncharacterized conserved protein YggE, contains kinase-interacting SIMPL domain	243
649915310	351	44.44	22	351	1	322	7.0e-89	321	COG2896	Molybdenum cofactor biosynthesis enzyme MoaA	322
649915311	428	36.2	177	336	11	171	4.0e-29	122	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
649915314	289	34.08	12	289	2	309	4.0e-69	254	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
649915316	559	63.15	4	542	2	533	0.0e+00	850	COG0504	CTP synthase (UTP-ammonia lyase)	533
649915318	134	19.7	1	129	1	126	2.0e-03	35	COG5455	Periplasmic regulator RcnB of Ni and Co efflux	129
649915320	142	20.3	5	133	2	130	2.0e-07	48.6	COG1848	Predicted nucleic acid-binding protein, contains PIN domain	140
649915322	275	60	1	273	1	271	6.0e-104	370	COG2877	3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase	279
649915326	150	52.67	1	149	4	153	6.0e-50	189	COG1225	Peroxiredoxin	157
649915328	239	34.59	52	236	1	175	7.0e-25	107	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
649915331	502	59.49	34	501	9	477	0.0e+00	641	COG2308	Uncharacterized conserved protein, circularly permuted ATPgrasp superfamily	488
649915333	329	36.31	1	321	1	309	1.0e-60	227	COG2307	Uncharacterized conserved protein, Alpha-E superfamily	313
649915334	329	28.85	1	288	11	313	2.0e-34	140	COG1305	Transglutaminase-like enzyme, putative cysteine protease	319
649915335	248	25.79	1	245	3	254	7.0e-29	121	COG0300	Short-chain dehydrogenase	265
649915336	458	19.86	27	445	24	442	1.0e-33	137	COG0277	FAD/FMN-containing dehydrogenase	459
649915337	190	30.22	5	184	14	193	6.0e-20	90.8	COG3230	Heme oxygenase	196
649915339	129	59.48	1	116	1	116	2.0e-32	131	COG0292	Ribosomal protein L20	118
649915340	65	63.08	1	65	1	65	4.0e-10	56.4	COG0291	Ribosomal protein L35	65
649915341	606	16.79	72	466	66	448	1.0e-03	38.6	COG1807	4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferase of PMT family	535
649915342	877	59.35	25	603	2	578	0.0e+00	826	COG0187	DNA gyrase/topoisomerase IV, subunit B	635
649915344	136	37.31	1	134	2	131	1.0e-21	95.6	COG1487	Predicted nucleic acid-binding protein, contains PIN domain	133
649915345	396	28.88	23	385	21	425	1.0e-49	190	COG3325	Chitinase, GH18 family	441
649915346	613	30.65	128	612	3	475	2.0e-75	276	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
649915347	236	37.34	1	234	1	241	6.0e-48	184	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
649915349	94	37.5	7	86	5	84	1.0e-12	64.8	COG4095	Uncharacterized conserved protein, contains PQ loop repeat	89
649915350	147	30.1	32	134	5	94	4.0e-12	64.2	COG3536	Uncharacterized conserved protein, DUF971 family	120
649915355	493	26.14	71	481	43	443	4.0e-29	123	COG1538	Outer membrane protein TolC	457
649915358	352	25.76	43	311	18	311	4.0e-22	99.3	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
649915359	541	25.09	268	535	65	328	3.0e-29	123	COG0642	Signal transduction histidine kinase	336
649915360	608	60.87	10	605	5	602	0.0e+00	896	COG1217	Predicted membrane GTPase involved in stress response	603
649915362	309	36.46	101	278	32	202	1.0e-35	143	COG1611	Predicted Rossmann fold nucleotide-binding protein	205
649915363	588	40.19	50	542	1	492	2.0e-90	327	COG0366	Glycosidase	505
649915365	640	43.68	1	532	3	527	0.0e+00	536	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
649915367	946	39.14	21	946	1	910	0.0e+00	746	COG2352	Phosphoenolpyruvate carboxylase	910
649915370	443	36.47	27	437	15	421	2.0e-75	276	COG0738	Fucose permease	422
649915371	689	44	16	263	1	250	1.0e-67	251	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
649915375	1452	26.62	103	557	11	430	4.0e-49	191	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
649915376	379	36.92	36	374	4	307	3.0e-58	219	COG2017	Galactose mutarotase or related enzyme	308
649915377	307	28.75	3	306	8	327	5.0e-38	151	COG0506	Proline dehydrogenase	391
649915378	487	22.17	75	464	4	364	2.0e-27	117	COG0006	Xaa-Pro aminopeptidase	384
649915382	242	24.19	27	241	25	230	2.0e-22	99.4	COG1802	DNA-binding transcriptional regulator, GntR family	230
649915383	530	42.95	51	530	1	470	8.0e-122	431	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
649915384	521	27.77	6	515	4	490	6.0e-70	258	COG2939	Carboxypeptidase C (cathepsin A)	498
649915387	433	26.82	1	433	2	402	9.0e-35	141	COG1819	UDP:flavonoid glycosyltransferase YjiC, YdhE family	406
649915390	213	34.47	6	180	4	205	1.0e-26	113	COG3179	Predicted chitinase	206
649915393	436	25.89	1	429	7	454	2.0e-28	120	COG0531	Amino acid transporter	466
649915395	176	48.77	12	172	10	171	4.0e-46	177	COG0221	Inorganic pyrophosphatase	171
649915396	88	41.98	8	88	2	81	6.0e-17	79.1	COG1828	Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component	83
649915398	384	27.88	1	377	4	381	2.0e-35	143	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649915401	921	16.78	100	510	7	419	5.0e-17	83.6	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
649915402	113	36.36	10	108	8	105	1.0e-12	64.9	COG1695	DNA-binding transcriptional regulator, PadR family	138
649915403	138	41.54	70	133	2	66	2.0e-08	51.9	COG3585	Molybdopterin-binding protein	69
649915407	244	31.91	4	229	8	239	2.0e-37	149	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
649915409	644	50.7	1	644	1	597	0.0e+00	745	COG0449	Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains	597
649915410	270	37.82	4	270	2	272	2.0e-48	186	COG0338	Site-specific DNA-adenine methylase	274
649915414	187	38.32	1	166	2	152	2.0e-40	158	COG0242	Peptide deformylase	168
649915420	329	42.68	16	329	14	321	3.0e-79	288	COG4301	Uncharacterized conserved protein, contains predicted SAM-dependent methyltransferase domain	321
649915421	449	26.37	202	449	51	311	1.0e-27	117	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
649915422	842	18.69	22	436	4	418	3.0e-18	87.9	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
649915423	227	44.25	1	224	1	226	1.0e-65	243	COG1136	ABC-type lipoprotein export system, ATPase component	226
649915425	493	27.27	47	490	5	444	3.0e-52	199	COG1231	Monoamine oxidase	450
649915426	195	20.21	2	194	8	198	8.0e-10	57.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
649915427	269	42.75	7	267	4	265	3.0e-69	255	COG0300	Short-chain dehydrogenase	265
649915428	281	39.11	14	258	3	223	6.0e-36	144	COG1040	Predicted amidophosphoribosyltransferases	225
649915429	236	33.33	73	203	1	128	1.0e-12	66.9	COG1403	5-methylcytosine-specific restriction endonuclease McrA	146
649915432	636	47.96	73	608	2	532	0.0e+00	520	COG0539	Ribosomal protein S1	541
649915433	317	28.78	40	310	38	292	1.0e-10	61.1	COG5006	Threonine/homoserine efflux transporter RhtA	292
649915434	271	22.95	24	263	2	224	1.0e-16	80.5	COG3828	Type 1 glutamine amidotransferase (GATase1)-like domain	239
649915435	355	64.16	20	351	1	332	0.0e+00	481	COG2255	Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit	332
649915436	376	30.21	1	376	1	369	6.0e-26	112	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
649915437	838	20.8	58	827	66	915	5.0e-16	80.4	COG5373	Uncharacterized membrane protein	931
649915438	359	36.2	1	336	1	312	4.0e-61	228	COG2826	Transposase and inactivated derivatives, IS30 family	318
649915439	179	33.87	43	166	11	131	3.0e-16	78	COG1664	Cytoskeletal protein CcmA, bactofilin family	146
649915441	202	31.12	4	190	12	200	4.0e-25	108	COG2191	Formylmethanofuran dehydrogenase subunit E	206
649915442	183	29.79	4	183	9	190	3.0e-21	95	COG0352	Thiamine monophosphate synthase	211
649915444	379	20.69	11	349	2	360	1.0e-13	71.4	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
649915445	270	44.57	1	269	1	272	2.0e-71	262	COG0266	Formamidopyrimidine-DNA glycosylase	273
649915447	435	54.74	5	425	2	423	0.0e+00	578	COG0104	Adenylosuccinate synthase	430
649915448	95	33.78	1	74	3	76	3.0e-12	63.5	COG1359	Quinol monooxygenase YgiN	100
649915449	177	23.58	34	151	3	125	1.0e-06	46.5	COG4319	Ketosteroid isomerase homolog	137
649915451	191	30.92	36	186	2	138	1.0e-28	119	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
649915452	492	43.47	5	492	4	464	0.0e+00	519	COG0215	Cysteinyl-tRNA synthetase	464
649915453	379	47.18	6	378	2	332	2.0e-102	366	COG0533	tRNA A37 threonylcarbamoyltransferase TsaD	342
649915454	457	35.62	13	445	6	400	8.0e-71	261	COG0617	tRNA nucleotidyltransferase/poly(A) polymerase	412
649915455	447	23.97	4	440	10	444	9.0e-33	135	COG1231	Monoamine oxidase	450
649915456	354	34.03	39	322	9	282	1.0e-47	184	COG1533	DNA repair photolyase	297
649915460	458	27.23	1	457	1	399	1.0e-58	220	COG2133	Glucose/arabinose dehydrogenase, beta-propeller fold	399
649915461	144	64.79	3	144	1	140	3.0e-47	180	COG0080	Ribosomal protein L11	141
649915462	209	48.86	33	207	2	177	2.0e-47	182	COG0250	Transcription antitermination factor NusG	178
649915463	86	28.57	14	76	9	71	4.0e-06	43.1	COG0690	Preprotein translocase subunit SecE	73
649915465	49	55.1	1	49	2	50	2.0e-08	50.6	COG0267	Ribosomal protein L33	50
649915466	395	75.19	1	395	1	394	0.0e+00	678	COG0050	Translation elongation factor EF-Tu, a GTPase	394
649915473	245	36.44	6	226	4	214	6.0e-33	134	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
649915475	451	18.76	50	449	35	459	1.0e-21	98	COG0277	FAD/FMN-containing dehydrogenase	459
649915476	153	25.93	1	153	5	166	7.0e-06	43.5	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
649915478	794	21.94	31	607	7	581	2.0e-64	241	COG3250	Beta-galactosidase/beta-glucuronidase	808
649915479	483	40.7	39	480	2	453	2.0e-111	396	COG2723	Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase	460
649915481	330	37.46	6	328	2	316	1.0e-57	217	COG0611	Thiamine monophosphate kinase	317
649915483	201	36.84	3	191	1	187	3.0e-37	148	COG0742	16S rRNA G966 N2-methylase RsmD	187
649915484	379	21.17	5	223	4	224	9.0e-09	55	COG1994	Zn-dependent protease (includes SpoIVFB)	230
649915485	293	48.39	9	287	1	269	6.0e-84	304	COG0313	16S rRNA C1402 (ribose-2'-O) methylase RsmI	275
649915486	158	75.33	9	158	5	154	4.0e-63	233	COG3558	Uncharacterized conserved protein, nuclear transport factor 2 (NTF2) superfamily	154
649915492	325	43.56	23	319	4	299	5.0e-84	304	COG0031	Cysteine synthase	300
649915493	145	23.48	1	128	1	120	1.0e-10	59	COG1310	Proteasome lid subunit RPN8/RPN11, contains Jab1/MPN domain metalloenzyme (JAMM) motif	134
649915494	498	54.94	106	353	2	254	2.0e-75	276	COG0476	Molybdopterin or thiamine biosynthesis adenylyltransferase	254
649915496	243	36.4	2	239	1	249	6.0e-43	167	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
649915497	472	21.88	72	460	18	439	4.0e-33	136	COG1524	Predicted pyrophosphatase or phosphodiesterase, AlkP superfamily	450
649915498	449	36.39	27	340	1	327	6.0e-72	265	COG0460	Homoserine dehydrogenase	333
649915499	161	38.1	1	125	1	125	5.0e-33	133	COG0590	tRNA(Arg) A34 adenosine deaminase TadA	152
649915500	455	38.98	17	445	9	428	2.0e-100	360	COG0044	Dihydroorotase or related cyclic amidohydrolase	430
649915501	171	27.88	5	164	8	168	3.0e-09	55.3	COG3195	2-oxo-4-hydroxy-4-carboxy--5-ureidoimidazoline (OHCU) decarboxylase	176
649915502	112	42.11	3	112	11	124	9.0e-28	115	COG2351	5-hydroxyisourate hydrolase (purine catabolism), transthyretin-related family	124
649915503	280	33.68	9	280	15	298	2.0e-54	205	COG3648	Uricase (urate oxidase)	299
649915504	402	23.87	28	396	27	407	5.0e-32	132	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
649915505	246	35.06	1	238	11	261	9.0e-54	203	COG3257	Uncharacterized protein, possibly involved in glyoxylate utilization	264
649915506	419	20.63	16	418	5	408	2.0e-28	120	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
649915507	454	41.45	1	453	14	467	2.0e-119	422	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
649915508	973	13.92	119	764	37	680	5.0e-04	40.7	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
649915510	582	29.39	3	576	39	627	1.0e-117	417	COG0296	1,4-alpha-glucan branching enzyme	628
649915511	889	43.87	3	888	2	889	0.0e+00	806	COG3280	Maltooligosyltrehalose synthase	889
649915513	1081	35.93	21	524	1	505	1.0e-96	348	COG0366	Glycosidase	505
649915516	84	25.32	1	79	1	79	9.0e-07	45.3	COG0236	Acyl carrier protein	80
649915518	927	47.79	6	519	1	514	7.0e-127	448	COG0210	Superfamily I DNA or RNA helicase	655
649915520	523	29.67	23	523	1	460	8.0e-42	165	COG0531	Amino acid transporter	466
649915521	239	26.74	6	190	19	196	4.0e-16	78.6	COG3361	Uncharacterized protein YqjF, DUF2071 family	240
649915526	328	53.55	18	325	3	310	3.0e-94	338	COG0331	Malonyl CoA-acyl carrier protein transacylase	310
649915527	277	54.34	9	271	1	265	3.0e-100	358	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
649915528	253	23.15	1	214	2	152	2.0e-08	53.5	COG0622	Predicted phosphodiesterase	172
649915529	734	31.29	26	333	6	306	2.0e-36	148	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
649915530	132	38.46	15	131	4	112	9.0e-16	76	COG0792	Predicted endonuclease distantly related to archaeal Holliday junction resolvase	114
649915533	1261	21.14	213	983	42	788	2.0e-28	122	COG2374	Predicted extracellular nuclease	798
649915534	197	20.92	11	187	6	199	5.0e-03	34.6	COG3637	Opacity protein and related surface antigens	199
649915536	624	23.47	46	617	10	597	8.0e-50	192	COG3250	Beta-galactosidase/beta-glucuronidase	808
649915538	821	25.81	133	341	24	239	4.0e-19	90.6	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
649915542	623	40.53	75	592	20	545	1.0e-130	460	COG3882	Predicted enzyme involved in methoxymalonyl-ACP biosynthesis	574
649915544	349	25.94	1	330	1	331	5.0e-29	122	COG0859	ADP-heptose:LPS heptosyltransferase	334
649915545	194	36.02	1	185	4	181	4.0e-40	158	COG0241	Histidinol phosphatase or a related phosphatase	181
649915546	250	44.71	49	250	37	226	2.0e-56	212	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
649915547	388	24.22	1	360	1	376	2.0e-20	93.5	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649915549	108	40	9	108	2	96	2.0e-17	80.6	COG0721	Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit	96
649915550	482	50.82	1	480	2	466	0.0e+00	474	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
649915553	465	38.16	1	454	1	454	2.0e-116	412	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
649915554	372	27.73	12	352	14	368	9.0e-41	161	COG1680	CubicO group peptidase, beta-lactamase class C family	390
649915555	633	46.17	163	631	4	442	0.0e+00	471	COG1160	Predicted GTPases	444
649915556	673	34.93	18	665	1	646	3.0e-121	429	COG1199	Rad3-related DNA helicase	654
649915560	761	28.17	12	712	2	613	2.0e-77	284	COG1297	Uncharacterized membrane protein, oligopeptide transporter (OPT) family	624
649915562	94	41.46	8	89	6	87	2.0e-14	70.4	COG5606	Predicted DNA-binding protein, XRE-type HTH domain	91
649915563	223	37.06	9	205	1	169	1.0e-36	146	COG1778	 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsC and related HAD superfamily phosphatases	170
649915564	252	44.77	9	247	11	229	1.0e-52	200	COG0571	dsRNA-specific ribonuclease	235
649915566	255	22.47	8	185	2	157	7.0e-11	61.2	COG0681	Signal peptidase I	166
649915567	265	20.81	17	165	4	138	1.0e-08	53.8	COG0681	Signal peptidase I	166
649915570	263	42.91	1	246	21	260	1.0e-59	222	COG0566	tRNA G18 (ribose-2'-O)-methylase SpoU	260
649915571	210	32.62	17	203	1	182	2.0e-22	99.4	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
649915574	278	34.42	3	278	2	243	8.0e-45	174	COG3279	DNA-binding response regulator, LytR/AlgR family	244
649915577	558	44.46	1	549	2	552	0.0e+00	567	COG3961	TPP-dependent 2-oxoacid decarboxylase, includes indolepyruvate decarboxylase	557
649915578	436	23.21	81	427	63	382	3.0e-09	57.1	COG2814	Predicted arabinose efflux permease, MFS family	394
649915579	365	24.01	47	354	28	350	4.0e-31	129	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
649915580	276	41.24	4	273	12	280	3.0e-72	265	COG2897	3-mercaptopyruvate sulfurtransferase SseA, contains two rhodanese domains	285
649915581	218	35.61	1	199	1	193	7.0e-55	206	COG0450	Alkyl hydroperoxide reductase subunit AhpC (peroxiredoxin)	194
649915582	179	37.97	13	170	28	182	6.0e-26	110	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
649915583	255	26.06	1	254	1	282	2.0e-20	92.8	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
649915585	230	26.32	1	215	3	212	5.0e-19	88.2	COG0543	NAD(P)H-flavin reductase	252
649915586	163	53.09	4	163	3	157	1.0e-49	189	COG0315	Molybdenum cofactor biosynthesis enzyme	157
649915587	403	42.61	1	402	3	400	2.0e-96	346	COG0303	Molybdopterin biosynthesis enzyme	404
649915588	143	35.71	21	131	1	112	9.0e-13	66.1	COG1846	DNA-binding transcriptional regulator, MarR family	126
649915589	819	23.51	543	819	118	419	2.0e-15	78.6	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
649915590	321	31.17	1	308	3	303	6.0e-46	178	COG2378	Predicted DNA-binding transcriptional regulator YafY, contains an HTH and WYL domains	311
649915591	160	18.99	10	155	1	156	7.0e-10	56.9	COG2318	Uncharacterized damage-inducible protein DinB (forms a four-helix bundle)	172
649915593	236	48.44	14	236	2	220	1.0e-64	239	COG0603	7-cyano-7-deazaguanine synthase (queuosine biosynthesis)	222
649915595	346	45.01	1	344	10	348	5.0e-84	304	COG5042	Purine nucleoside permease	349
649915597	285	52.65	3	285	6	287	2.0e-103	369	COG0788	Formyltetrahydrofolate hydrolase	287
649915598	229	31.14	1	222	4	210	1.0e-31	130	COG0602	Organic radical activating enzyme	212
649915599	125	39.2	1	125	2	126	3.0e-28	117	COG0720	6-pyruvoyl-tetrahydropterin synthase	127
649915604	1489	35.95	20	909	9	812	0.0e+00	651	COG1201	Lhr-like helicase	814
649915608	210	35.45	13	201	1	175	7.0e-26	110	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
649915610	297	35.09	5	284	1	279	4.0e-36	145	COG0583	DNA-binding transcriptional regulator, LysR family	297
649915612	165	47.24	1	163	1	163	2.0e-37	148	COG5472	Predicted small integral membrane protein	164
649915614	1082	28.9	2	1047	1	1009	0.0e+00	665	COG0841	Multidrug efflux pump subunit AcrB	1009
649915615	558	26.22	68	495	1	366	4.0e-25	109	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
649915616	713	26.34	334	704	111	453	7.0e-25	109	COG1538	Outer membrane protein TolC	457
649915618	353	19.93	14	310	5	290	1.0e-07	50.9	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
649915619	761	23.16	441	628	42	227	1.0e-11	65.8	COG3063	Tfp pilus assembly protein PilF	250
649915620	499	30.36	12	366	5	346	5.0e-48	185	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
649915624	611	30.73	32	607	7	565	1.0e-80	294	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
649915627	192	36.9	30	111	17	100	1.0e-10	59.6	COG1605	Chorismate mutase	101
649915629	322	25.1	42	278	20	240	2.0e-19	89.8	COG3000	Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily	271
649915630	248	29.73	27	239	21	241	3.0e-30	125	COG3403	Uncharacterized protein YcgG, contains conserved FPC and CPF motifs	257
649915631	602	20.35	1	587	1	600	8.0e-31	128	COG4206	Outer membrane cobalamin receptor protein	608
649915632	307	54.61	5	306	16	316	3.0e-103	368	COG0502	Biotin synthase or related enzyme	335
649915637	192	25.13	1	191	6	196	2.0e-09	55.8	COG1309	DNA-binding transcriptional regulator, AcrR family	201
649915639	248	43.91	1	227	1	229	6.0e-58	217	COG3967	Short-chain dehydrogenase involved in D-alanine esterification of teichoic acids	245
649915642	471	29.67	28	471	5	445	4.0e-57	216	COG1231	Monoamine oxidase	450
649915643	130	26.14	23	109	3	88	1.0e-06	45.3	COG2350	Uncharacterized conserved protein YciI, contains a putative active-site phosphohistidine	92
649915644	434	25.28	1	434	1	404	8.0e-39	154	COG1819	UDP:flavonoid glycosyltransferase YjiC, YdhE family	406
649915645	437	27.23	1	416	2	400	1.0e-50	194	COG1819	UDP:flavonoid glycosyltransferase YjiC, YdhE family	406
649915646	786	19.11	31	756	2	620	9.0e-20	92.9	COG1506	Dipeptidyl aminopeptidase/acylaminoacyl peptidase	620
649915649	220	28.41	33	208	1	174	5.0e-15	74.7	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
649915650	772	20.23	42	739	4	620	7.0e-22	99.9	COG1506	Dipeptidyl aminopeptidase/acylaminoacyl peptidase	620
649915653	215	30.86	28	202	1	173	7.0e-21	94	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
649915657	476	26.44	22	448	14	375	2.0e-33	137	COG0153	Galactokinase	390
649915658	299	33.33	55	299	6	253	6.0e-47	181	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
649915660	279	28.8	44	274	9	257	5.0e-31	128	COG0584	Glycerophosphoryl diester phosphodiesterase	257
649915663	409	27.6	1	409	2	387	6.0e-27	115	COG0475	Kef-type K+ transport system, membrane component KefB	397
649915664	319	34.81	12	319	4	261	5.0e-49	188	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
649915665	544	59.95	17	448	1	424	0.0e+00	595	COG2895	Sulfate adenylyltransferase subunit 1, EFTu-like GTPase family	431
649915666	255	38.26	33	255	22	248	3.0e-44	172	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
649915667	471	28.57	42	456	32	440	5.0e-53	202	COG0076	Glutamate or tyrosine decarboxylase or a related PLP-dependent protein	460
649915668	358	26.99	12	335	11	265	1.0e-26	114	COG1975	Xanthine and CO dehydrogenase maturation factor, XdhC/CoxF family	278
649915669	188	30.21	1	188	3	194	3.0e-31	128	COG2068	CTP:molybdopterin cytidylyltransferase MocA	199
649915670	477	22.86	40	424	36	361	2.0e-14	74.5	COG2814	Predicted arabinose efflux permease, MFS family	394
649915671	203	26.35	10	157	1	148	3.0e-08	52	COG1309	DNA-binding transcriptional regulator, AcrR family	201
649915672	550	29.25	36	535	2	487	5.0e-73	269	COG1233	Phytoene dehydrogenase-related protein	487
649915673	500	29.82	1	500	1	484	1.0e-71	264	COG1233	Phytoene dehydrogenase-related protein	487
649915674	185	30	8	184	1	180	3.0e-20	91.7	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
649915677	328	25.85	5	276	2	285	1.0e-12	68	COG3594	Fucose 4-O-acetylase or related acetyltransferase	343
649915680	109	30.3	5	103	4	101	1.0e-10	58.3	COG1695	DNA-binding transcriptional regulator, PadR family	138
649915681	905	21.1	523	905	8	419	5.0e-19	90.6	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
649915682	305	29.96	44	284	3	248	3.0e-24	105	COG1402	 Creatinine amidohydrolase/Fe(II)-dependent formamide hydrolase involved in riboflavin and F420 biosynthesis	250
649915685	114	36.08	11	107	4	100	3.0e-14	70.3	COG1695	DNA-binding transcriptional regulator, PadR family	138
649915686	260	20.93	12	218	35	239	2.0e-08	53	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
649915689	448	54.69	2	447	4	436	0.0e+00	577	COG1206	Folate-dependent tRNA-U54 methylase TrmFO/GidA	439
649915691	301	24.38	1	301	1	310	6.0e-16	78.3	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
649915692	338	24.58	44	336	4	279	1.0e-22	100	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
649915694	384	27.35	27	364	3	322	6.0e-36	145	COG0673	Predicted dehydrogenase	342
649915695	351	26.14	59	331	66	365	4.0e-30	125	COG1680	CubicO group peptidase, beta-lactamase class C family	390
649915698	247	25.45	22	244	12	225	1.0e-06	47.2	COG3619	Uncharacterized membrane protein YoaK, UPF0700 family	226
649915699	434	19.82	4	324	30	339	2.0e-15	77	COG3875	Nickel-dependent lactate racemase	423
649915700	229	20.13	50	195	26	170	5.0e-07	48	COG2825	Periplasmic chaperone for outer membrane proteins, Skp family	170
649915702	600	67.5	1	600	4	603	0.0e+00	1008	COG0481	Translation elongation factor EF-4, membrane-bound GTPase	603
649915705	182	45.51	29	181	1	156	7.0e-45	173	COG1225	Peroxiredoxin	157
649915706	293	37.01	7	284	6	275	6.0e-54	204	COG3494	Uncharacterized conserved protein, DUF1009 family	279
649915707	113	38.14	13	109	4	100	4.0e-20	90	COG2944	DNA-binding transcriptional regulator YiaG, XRE-type HTH domain	104
649915708	122	49.59	1	121	1	120	9.0e-30	122	COG4737	Uncharacterized protein	123
649915709	261	55.04	3	260	6	259	7.0e-84	303	COG1043	Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase	260
649915710	173	54.42	13	157	2	147	3.0e-45	174	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
649915712	269	40.54	12	264	1	249	4.0e-40	158	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
649915714	142	22.95	1	121	1	117	1.0e-06	46	COG2315	Predicted DNA-binding protein with ?double-wing? structural motif, MmcQ/YjbR family	118
649915716	417	39.17	12	416	5	399	1.0e-103	369	COG0162	Tyrosyl-tRNA synthetase	401
649915719	299	19.37	67	288	29	223	2.0e-09	56.8	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
649915723	522	19.43	1	520	3	540	7.0e-44	172	COG2303	Choline dehydrogenase or related flavoprotein	542
649915724	295	23.83	45	284	14	263	1.0e-21	97.2	COG1082	Sugar phosphate isomerase/epimerase	274
649915725	377	27.06	1	377	12	375	1.0e-23	104	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
649915728	444	16.25	1	358	1	358	2.0e-07	50.9	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
649915729	155	25.27	29	119	27	116	1.0e-09	56.2	COG0662	Mannose-6-phosphate isomerase, cupin superfamily	127
649915732	266	31.9	150	265	6	121	2.0e-22	99.6	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
649915733	184	39.66	15	183	5	178	2.0e-31	128	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
649915734	319	22.86	6	317	2	280	2.0e-21	97.1	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
649915735	362	58.75	118	277	1	158	4.0e-49	189	COG4804	Predicted nuclease of restriction endonuclease-like (RecB) superfamily,  DUF1016 family	159
649915736	145	30.69	29	129	5	104	4.0e-14	70.8	COG1733	DNA-binding transcriptional regulator, HxlR family	120
649915737	359	41.19	1	358	3	358	2.0e-85	309	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
649915738	239	27.23	8	239	7	235	3.0e-34	138	COG0412	Dienelactone hydrolase	236
649915739	249	21.21	13	247	20	282	1.0e-07	50.5	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
649915740	198	21.32	3	135	2	136	2.0e-07	49.5	COG1225	Peroxiredoxin	157
649915742	223	26.74	43	214	4	154	3.0e-20	92.2	COG1225	Peroxiredoxin	157
649915743	99	27.84	1	97	1	97	3.0e-10	56.9	COG1359	Quinol monooxygenase YgiN	100
649915744	577	35.74	238	555	1	304	3.0e-59	223	COG0492	Thioredoxin reductase	305
649915745	302	32.24	1	300	1	297	8.0e-37	147	COG0583	DNA-binding transcriptional regulator, LysR family	297
649915746	342	40.24	5	334	4	340	9.0e-78	284	COG1816	Adenosine deaminase	345
649915747	132	40.77	4	130	2	130	8.0e-27	112	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
649915748	127	37.4	1	123	2	124	7.0e-20	89.5	COG0239	Fluoride ion exporter CrcB/FEX, affects chromosome condensation	126
649915749	303	31.25	1	300	1	297	1.0e-34	140	COG0583	DNA-binding transcriptional regulator, LysR family	297
649915750	301	22.92	15	296	1	282	9.0e-17	81.3	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
649915751	189	25.9	45	175	35	168	2.0e-09	55.8	COG3576	Predicted flavin-nucleotide-binding protein, pyridoxine 5'-phosphate oxidase superfamily	173
649915752	255	29.73	24	236	23	217	3.0e-22	98.9	COG4117	Thiosulfate reductase cytochrome b subunit	221
649915755	252	34.01	21	217	7	200	1.0e-21	96.9	COG3222	Uncharacterized conserved protein, glycosyltransferase A (GT-A) superfamily, DUF2064 family	211
649915758	376	29.41	6	352	1	312	3.0e-42	166	COG0451	Nucleoside-diphosphate-sugar epimerase	314
649915760	619	36.8	34	602	1	586	2.0e-128	452	COG4805	Uncharacterized conserved protein, DUF885 familyt	588
649915762	196	41.58	4	193	3	187	6.0e-44	170	COG2094	3-methyladenine DNA glycosylase Mpg	200
649915763	181	29.09	16	180	2	166	2.0e-32	131	COG3663	G:T/U-mismatch repair DNA glycosylase	169
649915764	136	62.69	1	134	1	133	1.0e-44	172	COG3558	Uncharacterized conserved protein, nuclear transport factor 2 (NTF2) superfamily	154
649915765	181	27.78	18	171	15	176	8.0e-12	63.7	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
649915766	187	23.46	12	170	18	178	5.0e-05	41.2	COG1309	DNA-binding transcriptional regulator, AcrR family	201
649915775	1126	29.04	197	857	3	639	1.0e-83	305	COG0210	Superfamily I DNA or RNA helicase	655
649915779	439	25.69	26	326	2	311	2.0e-34	140	COG0420	DNA repair exonuclease SbcCD nuclease subunit	390
649915780	1150	17.96	372	1135	191	972	3.0e-25	111	COG4717	Uncharacterized protein YhaN	984
649915782	678	20.26	227	640	148	590	4.0e-27	116	COG3505	Type IV secretory pathway, VirD4 component, TraG/TraD family ATPase	596
649915786	124	31.97	1	115	1	122	3.0e-16	77.4	COG0629	Single-stranded DNA-binding protein	167
649915787	322	38.96	13	318	49	348	6.0e-58	218	COG4962	Pilus assembly protein, ATPase of CpaF family	355
649915788	268	22.67	13	234	18	217	8.0e-04	38.1	COG3701	Type IV secretory pathway, TrbF components	228
649915797	789	23.43	25	735	21	733	9.0e-49	189	COG3451	Type IV secretory pathway, VirB4 component	796
649915800	316	24.32	5	292	1	286	9.0e-18	84.3	COG0583	DNA-binding transcriptional regulator, LysR family	297
649915802	373	24.71	97	345	50	292	2.0e-18	86.8	COG4974	Site-specific recombinase XerD	300
649915806	441	24.41	23	333	1	320	1.0e-35	144	COG3669	Alpha-L-fucosidase	430
649915807	359	35.8	1	337	1	313	4.0e-60	225	COG2826	Transposase and inactivated derivatives, IS30 family	318
649915808	459	32.97	3	458	2	442	3.0e-74	272	COG1232	Protoporphyrinogen oxidase	444
649915809	371	30.56	23	337	7	314	4.0e-55	208	COG0276	Protoheme ferro-lyase (ferrochelatase)	320
649915810	366	47.71	22	366	8	351	3.0e-105	375	COG0407	Uroporphyrinogen-III decarboxylase	352
649915811	90	35.56	1	90	1	90	1.0e-20	91.6	COG2924	Fe-S cluster biosynthesis and repair protein YggX	90
649915812	893	38.2	90	840	57	706	0.0e+00	553	COG0557	Exoribonuclease R	706
649915813	439	29.31	83	425	3	342	5.0e-53	202	COG0673	Predicted dehydrogenase	342
649915815	292	29.55	7	290	5	292	2.0e-40	159	COG1216	Glycosyltransferase, GT2 family	305
649915816	447	29.19	20	312	4	293	1.0e-41	164	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
649915817	368	28.27	16	283	7	278	2.0e-19	90.7	COG3594	Fucose 4-O-acetylase or related acetyltransferase	343
649915820	716	22.82	103	697	17	617	2.0e-40	161	COG1506	Dipeptidyl aminopeptidase/acylaminoacyl peptidase	620
649915821	240	37.13	9	240	3	239	4.0e-46	178	COG0565	tRNA C32,U32 (ribose-2'-O)-methylase TrmJ or a related methyltransferase	242
649915823	592	32.47	1	577	2	554	2.0e-93	337	COG0358	DNA primase (bacterial type)	568
649915825	186	32.85	12	137	49	185	4.0e-09	54.7	COG2020	Protein-S-isoprenylcysteine O-methyltransferase Ste14	187
649915826	350	30.23	3	296	2	289	1.0e-46	181	COG0859	ADP-heptose:LPS heptosyltransferase	334
649915827	328	35.58	2	318	16	328	6.0e-55	208	COG1663	Tetraacyldisaccharide-1-P 4'-kinase	336
649915828	439	38.96	1	433	1	419	3.0e-90	326	COG1519	3-deoxy-D-manno-octulosonic-acid transferase	419
649915831	432	41.34	250	427	4	181	1.0e-41	164	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
649915832	144	51.02	1	143	3	146	2.0e-34	138	COG0756	dUTPase	148
649915833	808	44.24	27	793	22	741	0.0e+00	785	COG0046	Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain	743
649915835	619	53.33	125	583	1	457	0.0e+00	613	COG0034	Glutamine phosphoribosylpyrophosphate amidotransferase	470
649915839	428	51.05	1	426	1	426	0.0e+00	506	COG0151	Phosphoribosylamine-glycine ligase	428
649915840	446	39	10	445	1	414	6.0e-76	278	COG1914	Mn2+ and Fe2+ transporters of the NRAMP family	416
649915843	149	36.72	28	149	1	128	4.0e-19	87.3	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
649915845	946	58.53	5	942	1	859	0.0e+00	1186	COG1048	Aconitase A	861
649915847	148	24.26	5	140	6	129	3.0e-03	34.5	COG4113	Predicted nucleic acid-binding protein, contains PIN domain	134
649915848	555	26.49	40	352	16	324	9.0e-35	142	COG3669	Alpha-L-fucosidase	430
649915849	410	31.39	1	390	1	380	2.0e-43	170	COG0644	Dehydrogenase (flavoprotein)	396
649915851	193	20.94	1	189	5	195	4.0e-10	58.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
649915852	286	32.64	2	242	6	232	1.0e-37	150	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
649915853	230	53.75	44	203	1	159	6.0e-62	230	COG0225	Peptide methionine sulfoxide reductase MsrA	174
649915854	469	25.41	1	344	7	364	2.0e-36	147	COG1680	CubicO group peptidase, beta-lactamase class C family	390
649915855	308	59.14	9	308	1	295	1.0e-103	369	COG2103	N-acetylmuramic acid 6-phosphate (MurNAc-6-P) etherase	298
649915857	758	31.55	108	739	146	765	3.0e-113	402	COG1501	Alpha-glucosidase, glycosyl hydrolase family GH31	772
649915858	147	29.93	1	147	2	147	4.0e-17	80.6	COG3238	Uncharacterized membrane protein YdcZ, DUF606 family	150
649915859	564	19.06	111	562	34	424	3.0e-15	77.3	COG3664	Beta-xylosidase	428
649915860	204	27.5	39	195	40	195	6.0e-11	60.7	COG4430	Uncharacterized conserved protein YdeI, YjbR/CyaY-like superfamily, DUF1801 family	200
649915861	440	21.58	36	414	3	342	3.0e-33	136	COG0673	Predicted dehydrogenase	342
649915862	175	21.89	7	173	15	164	5.0e-08	51.1	COG3477	Uncharacterized membrane protein YagU, involved in acid resistance, DUF1440 family	176
649915863	296	21.58	150	274	3	138	4.0e-07	49.1	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
649915865	273	28.52	1	273	1	281	4.0e-28	118	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
649915866	124	25.64	9	123	14	129	1.0e-16	78.8	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
649915868	242	44.16	7	236	8	233	7.0e-60	224	COG3910	Predicted ATPase	233
649915869	713	28.81	58	593	12	467	7.0e-73	269	COG1964	Uncharacterized Fe-S cluster-containing enzyme, radical SAM superfamily	514
649915871	206	38.42	4	203	6	205	5.0e-40	157	COG0522	Ribosomal protein S4 or related protein	205
649915875	273	40.56	19	197	5	184	3.0e-33	135	COG0797	Rare lipoprotein A, peptidoglycan hydrolase digesting "naked" glycans, contains C-terminal SPOR domain	233
649915876	203	38.65	6	203	3	209	5.0e-43	167	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
649915877	355	28.78	37	355	33	365	3.0e-38	152	COG4585	Signal transduction histidine kinase	365
649915878	259	23.53	35	254	68	281	9.0e-07	47.6	COG0842	ABC-type multidrug transport system, permease component	286
649915879	297	35.71	7	291	6	291	9.0e-61	227	COG1131	ABC-type multidrug transport system, ATPase component	293
649915882	411	53.08	11	347	7	347	1.0e-107	383	COG1171	Threonine dehydratase	347
649915883	149	25	21	136	1	116	2.0e-06	44.9	COG1846	DNA-binding transcriptional regulator, MarR family	126
649915885	285	28.27	9	284	5	278	5.0e-44	171	COG0287	Prephenate dehydrogenase	279
649915886	227	34.45	1	226	1	235	4.0e-40	158	COG0412	Dienelactone hydrolase	236
649915887	342	57.88	64	336	14	286	7.0e-102	363	COG2876	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase	286
649915888	90	30.68	1	86	8	95	5.0e-10	56.1	COG1605	Chorismate mutase	101
649915889	260	45.42	6	256	14	262	2.0e-72	265	COG0159	Tryptophan synthase alpha chain	265
649915890	409	69.05	19	409	7	396	0.0e+00	648	COG0133	Tryptophan synthase beta chain	396
649915891	258	23.14	8	253	3	254	4.0e-15	75.5	COG5662	Transmembrane transcriptional regulator (anti-sigma factor RsiW)	256
649915892	177	39.02	7	170	14	176	6.0e-32	130	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
649915894	258	44.35	135	252	10	128	4.0e-24	105	COG3474	Cytochrome c2	135
649915899	242	35.96	1	227	2	208	7.0e-43	167	COG0135	Phosphoribosylanthranilate isomerase	208
649915900	267	49.02	6	260	1	253	4.0e-75	274	COG0134	Indole-3-glycerol phosphate synthase	254
649915904	181	54.11	1	146	31	176	3.0e-49	188	COG0290	Translation initiation factor IF-3	176
649915908	753	35	493	732	19	227	4.0e-43	170	COG0860	N-acetylmuramoyl-L-alanine amidase	231
649915909	889	48.18	5	888	7	879	0.0e+00	981	COG0013	Alanyl-tRNA synthetase	879
649915910	391	41.1	206	367	11	171	3.0e-32	132	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
649915913	181	32.48	15	170	19	170	9.0e-13	66.8	COG2137	SOS response regulatory protein OraA/RecX, interacts with RecA	174
649915918	96	19.51	1	80	1	81	1.0e-05	41.8	COG2026	mRNA-degrading endonuclease RelE, toxin component of the RelBE toxin-antitoxin system	90
649915920	960	47.82	29	897	7	802	0.0e+00	872	COG0188	DNA gyrase/topoisomerase IV, subunit A	804
649915923	246	28.02	1	206	2	193	2.0e-32	132	COG0300	Short-chain dehydrogenase	265
649915925	880	20.42	493	880	2	419	1.0e-14	75.9	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
649915926	118	34.65	7	107	1	100	6.0e-16	76.4	COG1695	DNA-binding transcriptional regulator, PadR family	138
649915927	140	42.15	7	127	26	146	9.0e-28	115	COG5616	TolB amino-terminal domain (function unknown)	152
649915928	135	24.82	1	129	2	137	3.0e-06	44.4	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
649915929	901	18.24	11	294	2	310	4.0e-03	37.6	COG3420	Nitrous oxidase accessory protein NosD, contains tandem CASH domains	408
649915932	500	59.6	3	497	5	497	0.0e+00	719	COG0554	Glycerol kinase	499
649915933	528	41.89	3	525	1	530	2.0e-130	459	COG0578	Glycerol-3-phosphate dehydrogenase	532
649915934	246	41.87	1	244	4	238	2.0e-40	159	COG0580	Glycerol uptake facilitator and related aquaporins (Major Intrinsic Protein Family)	241
649915935	189	48.09	6	188	1	162	2.0e-56	212	COG0386	Glutathione peroxidase, house-cleaning role in reducing lipid peroxides	162
649915937	67	61.19	1	66	1	67	5.0e-21	92.9	COG1278	Cold shock protein, CspA family	67
649915938	215	45.02	2	202	4	214	5.0e-44	170	COG3132	Uncharacterized conserved protein YceH, UPF0502 family	215
649915940	301	28.14	40	301	23	260	7.0e-29	121	COG3358	Uncharacterized conserved protein, DUF1684 family	262
649915942	147	23.91	8	136	2	135	7.0e-05	40.1	COG1848	Predicted nucleic acid-binding protein, contains PIN domain	140
649915944	355	32.45	27	353	1	333	5.0e-55	208	COG0673	Predicted dehydrogenase	342
649915947	430	27.75	1	416	2	399	9.0e-47	181	COG1819	UDP:flavonoid glycosyltransferase YjiC, YdhE family	406
649915950	244	44.22	74	220	39	182	7.0e-36	144	COG3108	Uncharacterized conserved protein YcbK, DUF882 family	185
649915951	569	31.36	64	550	78	550	9.0e-86	311	COG2989	Murein L,D-transpeptidase YcbB/YkuD	561
649915953	551	24.86	4	529	6	475	4.0e-62	232	COG2939	Carboxypeptidase C (cathepsin A)	498
649915954	438	34.72	34	438	1	393	2.0e-76	280	COG1092	23S rRNA G2069 N7-methylase RlmK or C1962 C5-methylase RlmI	393
649915955	136	41.44	14	123	13	122	4.0e-24	103	COG3654	Prophage maintenance system killer protein	132
649915958	152	29.75	13	133	22	121	1.0e-09	55.9	COG4316	Uncharacterized protein	138
649915960	397	34.86	1	390	2	350	2.0e-75	276	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
649915963	699	53.6	16	515	1	491	0.0e+00	677	COG0753	Catalase	496
649915964	251	43.2	3	247	2	249	6.0e-46	177	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
649915965	328	37.39	1	324	1	325	3.0e-53	202	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
649915966	95	32.22	6	95	9	97	2.0e-06	44	COG0640	DNA-binding transcriptional regulator, ArsR family	110
649915967	180	46.94	1	147	1	147	5.0e-38	150	COG0359	Ribosomal protein L9	148
649915968	71	44.12	1	67	1	68	2.0e-10	57.3	COG1598	Predicted nuclease of the RNAse H fold, HicB family	73
649915969	127	58.21	55	121	9	75	2.0e-21	94.5	COG0238	Ribosomal protein S18	75
649915970	166	37.84	3	113	1	111	6.0e-26	110	COG0360	Ribosomal protein S6	112
649915971	201	41.84	1	195	2	190	2.0e-52	199	COG0193	Peptidyl-tRNA hydrolase	190
649915972	233	35.71	18	101	12	93	1.0e-13	70.3	COG1825	Ribosomal protein L25 (general stress protein Ctc)	93
649915973	362	54.95	51	361	2	313	1.0e-112	400	COG0462	Phosphoribosylpyrophosphate synthetase	314
649915975	346	29.03	1	310	2	269	2.0e-45	176	COG1947	4-diphosphocytidyl-2C-methyl-D-erythritol kinase	289
649915976	434	22.84	1	425	1	406	8.0e-41	161	COG1819	UDP:flavonoid glycosyltransferase YjiC, YdhE family	406
649915977	161	45.95	38	148	35	145	2.0e-25	108	COG0071	Molecular chaperone IbpA, HSP20 family	146
649915978	869	55.18	7	863	1	781	0.0e+00	934	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
649915979	348	28.53	3	322	2	314	1.0e-39	157	COG0451	Nucleoside-diphosphate-sugar epimerase	314
649915981	544	20.4	5	498	3	439	4.0e-38	153	COG1232	Protoporphyrinogen oxidase	444
649915984	286	40.64	7	285	1	276	9.0e-58	217	COG2890	Methylase of polypeptide chain release factors	280
649915985	355	60.72	1	354	5	363	0.0e+00	486	COG0216	Protein chain release factor A	363
649915987	153	30.28	33	141	13	120	3.0e-16	77.7	COG1733	DNA-binding transcriptional regulator, HxlR family	120
649915988	285	31.17	1	242	3	236	3.0e-41	162	COG0300	Short-chain dehydrogenase	265
649915989	303	30.58	14	214	4	193	9.0e-23	101	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
649915990	630	31.16	141	620	40	443	4.0e-62	232	COG1793	ATP-dependent DNA ligase	444
649915991	627	18.01	49	456	31	442	3.0e-19	90.6	COG0531	Amino acid transporter	466
649915992	649	19.15	63	638	10	600	2.0e-24	108	COG4206	Outer membrane cobalamin receptor protein	608
649915993	350	43.5	1	330	1	314	3.0e-84	305	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
649915995	307	43.01	1	278	20	296	8.0e-62	230	COG1230	Co/Zn/Cd efflux system component	296
649915996	144	43.04	51	128	24	100	8.0e-14	69.7	COG0633	Ferredoxin	102
649915997	71	54.84	7	68	3	64	2.0e-14	70.8	COG2975	Fe-S-cluster formation regulator IscX/YfhJ	64
649915998	171	29.68	4	151	4	158	3.0e-15	74.6	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
649915999	587	27.29	85	574	12	511	7.0e-45	175	COG0728	Peptidoglycan biosynthesis protein MviN/MurJ, putative lipid II flippase	518
649916000	359	36.2	1	336	1	312	2.0e-61	229	COG2826	Transposase and inactivated derivatives, IS30 family	318
649916001	522	30.52	25	520	17	465	6.0e-64	238	COG2027	D-alanyl-D-alanine carboxypeptidase	470
649916005	303	55.99	16	299	19	302	2.0e-115	408	COG0320	Lipoate synthase	306
649916007	98	24.36	14	86	9	86	5.0e-03	32.7	COG2161	Antitoxin component YafN of the YafNO toxin-antitoxin module, PHD/YefM family	86
649916010	194	49.73	11	193	4	186	2.0e-53	202	COG0233	Ribosome recycling factor	187
649916011	73	31.34	1	65	1	66	2.0e-04	37.2	COG1724	Predicted RNA binding protein YcfA, dsRBD-like fold, HicA-like mRNA interferase family	66
649916013	157	22.73	31	156	1	129	4.0e-05	41.1	COG4319	Ketosteroid isomerase homolog	137
649916014	758	33.07	7	714	31	761	1.0e-127	451	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
649916015	979	25.37	47	925	6	752	1.0e-98	355	COG4775	Outer membrane protein assembly factor BamA	766
649916016	459	17.19	323	449	13	140	2.0e-04	40.9	COG1714	Uncharacterized membrane protein YckC, RDD family	172
649916018	333	26.4	119	313	70	243	6.0e-15	75.2	COG1651	Protein-disulfide isomerase	244
649916019	360	17.47	75	356	56	320	5.0e-03	35.8	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
649916021	262	18.78	52	261	36	244	7.0e-09	54.8	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
649916023	395	23.41	1	380	7	387	7.0e-26	111	COG1680	CubicO group peptidase, beta-lactamase class C family	390
649916025	145	33.33	1	138	2	132	5.0e-21	93.4	COG0848	Biopolymer transport protein ExbD	137
649916026	140	36.23	1	138	1	135	4.0e-28	117	COG0848	Biopolymer transport protein ExbD	137
649916027	251	31.94	37	251	1	215	1.0e-31	129	COG0811	Biopolymer transport protein ExbB/TolQ	216
649916028	243	22.75	56	242	74	244	8.0e-08	50.9	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
649916030	479	24.42	34	463	4	407	2.0e-48	187	COG0415	Deoxyribodipyrimidine photolyase	461
649916031	476	30.69	1	470	1	480	1.0e-68	254	COG1233	Phytoene dehydrogenase-related protein	487
649916032	382	25.99	34	381	2	304	6.0e-41	161	COG2152	Predicted glycosyl hydrolase, GH43/DUF377 family	314
649916034	322	37.39	1	319	6	338	5.0e-75	274	COG1559	Cell division protein YceG, involved in septum cleavage	342
649916035	157	41.61	13	148	3	139	5.0e-36	143	COG0816	RNase H-fold protein, predicted Holliday junction resolvase in Firmicutes and mycoplasms, involved in anti-termination at Rho-dependent terminators	141
649916036	157	40.28	6	149	6	148	1.0e-25	109	COG0782	Transcription elongation factor, GreA/GreB family	151
649916037	210	26.4	18	205	4	192	4.0e-15	75	COG0558	Phosphatidylglycerophosphate synthase	192
649916039	305	33.08	28	293	24	277	4.0e-53	202	COG0676	D-hexose-6-phosphate mutarotase	287
649916040	189	50.53	1	189	3	190	6.0e-54	203	COG0424	Predicted house-cleaning NTP pyrophosphatase, Maf/HAM1 superfamily	193
649916041	376	26.77	7	371	12	404	4.0e-40	159	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
649916043	546	22.61	84	509	2	379	1.0e-24	108	COG2234	Zn-dependent amino- or carboxypeptidase, M28 family	435
649916044	285	24.35	48	237	29	212	8.0e-13	68	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
649916046	320	45.02	35	319	4	294	1.0e-81	296	COG0774	UDP-3-O-acyl-N-acetylglucosamine deacetylase	300
649916048	521	30.75	47	516	5	443	7.0e-57	215	COG1231	Monoamine oxidase	450
649916049	444	24.9	159	411	86	297	1.0e-17	84.6	COG2382	Enterochelin esterase or related enzyme	299
649916050	154	50	1	150	2	150	2.0e-39	155	COG0801	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase	160
649916051	438	25.86	1	427	2	406	6.0e-34	138	COG1819	UDP:flavonoid glycosyltransferase YjiC, YdhE family	406
649916053	366	40.11	7	347	9	357	4.0e-81	295	COG1060	2-iminoacetate synthase ThiH (tyrosine cleavage enzyme, thamine biosynthesis)	370
649916054	258	29.03	12	252	9	242	1.0e-21	97.3	COG1427	Predicted periplasmic solute-binding protein	252
649916055	382	41.74	4	345	19	363	8.0e-99	354	COG1060	2-iminoacetate synthase ThiH (tyrosine cleavage enzyme, thamine biosynthesis)	370
649916056	280	40.39	12	266	3	252	2.0e-62	232	COG2107	Predicted periplasmic solute-binding protein	272
649916058	371	51.77	5	371	1	349	2.0e-129	455	COG0343	Queuine/archaeosine tRNA-ribosyltransferase	372
649916061	107	34.02	11	107	1	95	5.0e-13	66.4	COG1862	Preprotein translocase subunit YajC	97
649916062	526	38.2	1	519	1	500	5.0e-101	362	COG0342	Preprotein translocase subunit SecD	506
649916063	317	40.33	8	307	9	299	7.0e-70	257	COG0341	Preprotein translocase subunit SecF	305
649916065	244	29.63	26	241	19	206	3.0e-31	128	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
649916066	556	46.71	26	534	3	517	3.0e-130	459	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
649916067	347	33.67	29	220	28	222	5.0e-40	158	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
649916068	304	27.11	60	225	45	197	7.0e-15	74.7	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
649916073	480	21.65	56	454	15	386	2.0e-17	83.8	COG5557	Ni/Fe-hydrogenase 2 integral membrane subunit HybB	401
649916074	1066	27.56	832	1053	11	191	2.0e-36	148	COG0437	Fe-S-cluster-containing dehydrogenase component	203
649916076	635	27.08	3	480	1	435	3.0e-29	123	COG1807	4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferase of PMT family	535
649916078	363	22.67	16	325	21	333	4.0e-25	109	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
649916081	238	35.62	15	226	64	272	1.0e-40	159	COG0122	3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase	285
649916082	403	24.06	10	354	4	332	2.0e-22	100	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
649916083	417	29.31	21	417	1	419	3.0e-34	139	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
649916084	409	25.54	18	408	1	419	5.0e-27	116	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
649916085	336	31.34	62	313	2	256	2.0e-36	146	COG2220	L-ascorbate metabolism protein UlaG, beta-lactamase superfamily	258
649916087	151	27.95	1	147	8	168	7.0e-14	70	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
649916090	129	21.59	15	98	1	88	4.0e-08	50.4	COG5606	Predicted DNA-binding protein, XRE-type HTH domain	91
649916091	560	22.16	143	523	19	374	1.0e-19	91.9	COG2234	Zn-dependent amino- or carboxypeptidase, M28 family	435
649916092	167	41.72	4	153	1	149	3.0e-16	78.5	COG3918	Uncharacterized membrane protein	153
649916093	276	25.45	2	273	6	264	1.0e-28	120	COG2273	Beta-glucanase, GH16 family	355
649916096	464	35.36	3	459	2	454	1.0e-112	400	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
649916097	420	62.95	5	416	3	413	0.0e+00	636	COG0112	Glycine/serine hydroxymethyltransferase	413
649916103	397	37.76	9	397	2	360	8.0e-82	297	COG0787	Alanine racemase	360
649916105	121	34.78	8	121	13	125	6.0e-17	79.6	COG3324	Predicted enzyme related to lactoylglutathione lyase	127
649916107	463	45.23	13	451	3	432	2.0e-120	426	COG0305	Replicative DNA helicase	435
649916109	629	52.9	3	623	1	617	0.0e+00	829	COG0445	tRNA U34 5-carboxymethylaminomethyl modifying enzyme MnmG/GidA	621
649916110	139	26.87	1	134	2	127	3.0e-13	67.5	COG1487	Predicted nucleic acid-binding protein, contains PIN domain	133
649916112	292	28.52	4	287	2	259	2.0e-38	153	COG0300	Short-chain dehydrogenase	265
649916113	328	28.8	12	199	16	206	4.0e-22	99.2	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
649916114	242	24.86	39	200	4	181	1.0e-07	50.4	COG0412	Dienelactone hydrolase	236
649916115	139	46.76	1	139	2	140	1.0e-30	125	COG2510	Uncharacterized membrane protein	140
649916118	366	48.24	1	366	2	366	1.0e-127	450	COG0536	GTPase involved in cell partioning and DNA repair	369
649916119	135	36.45	17	123	13	118	2.0e-23	101	COG1733	DNA-binding transcriptional regulator, HxlR family	120
649916120	257	35.32	7	255	4	250	3.0e-38	151	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
649916123	191	35.35	1	190	3	196	7.0e-39	153	COG1057	Nicotinic acid mononucleotide adenylyltransferase	197
649916124	162	32.59	28	159	41	175	7.0e-17	80.2	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
649916125	441	37.74	29	441	13	391	2.0e-83	303	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
649916131	313	29.77	3	286	1	297	2.0e-24	107	COG0583	DNA-binding transcriptional regulator, LysR family	297
649916132	640	20	30	605	5	589	7.0e-45	175	COG1874	Beta-galactosidase GanA	673
649916133	201	44.44	5	120	2	115	8.0e-26	110	COG0799	Ribosomal silencing factor RsfS, regulates association of 30S and 50S subunits	115
649916135	165	36.54	22	162	2	154	1.0e-24	106	COG1576	23S rRNA pseudoU1915 N3-methylase RlmH	155
649916136	183	51.12	6	183	23	198	6.0e-57	213	COG2109	ATP:corrinoid adenosyltransferase	198
649916137	680	32.92	38	666	32	674	2.0e-118	420	COG0339	Zn-dependent oligopeptidase	683
649916138	400	32.51	3	399	17	408	1.0e-68	253	COG2124	Cytochrome P450	411
649916139	401	33.76	12	400	25	408	2.0e-70	260	COG2124	Cytochrome P450	411
649916141	396	41.04	1	382	11	394	7.0e-69	254	COG2814	Predicted arabinose efflux permease, MFS family	394
649916143	980	23.99	698	973	1	277	6.0e-07	50.4	COG3386	Sugar lactone lactonase YvrE	307
649916145	298	26.74	1	258	2	254	1.0e-24	107	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
649916146	273	29.23	1	273	1	281	3.0e-32	132	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
649916148	125	37.5	1	111	14	123	6.0e-17	79.7	COG3727	G:T-mismatch repair DNA endonuclease, very short patch repair protein	150
649916149	409	32.79	5	367	2	327	2.0e-60	226	COG0270	Site-specific DNA-cytosine methylase	328
649916151	702	25.77	140	702	24	618	1.0e-49	191	COG1506	Dipeptidyl aminopeptidase/acylaminoacyl peptidase	620
649916152	279	57.6	1	279	1	283	9.0e-111	393	COG0777	Acetyl-CoA carboxylase beta subunit	294
649916153	245	23	12	215	1	213	9.0e-15	74.1	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
649916157	289	29.71	1	270	8	282	9.0e-36	144	COG3315	O-Methyltransferase involved in polyketide biosynthesis	297
649916159	455	40.13	1	450	2	423	3.0e-92	332	COG0285	Folylpolyglutamate synthase/Dihydropteroate synthase	427
649916160	268	28.16	20	258	1	239	1.0e-23	103	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
649916161	277	37.1	1	185	4	189	4.0e-36	145	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
649916162	204	24.73	4	183	2	183	4.0e-06	45	COG1309	DNA-binding transcriptional regulator, AcrR family	201
649916164	298	36.3	11	291	5	288	3.0e-56	212	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
649916167	255	39.69	5	253	3	250	1.0e-42	166	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
649916168	97	24.18	1	89	1	91	1.0e-04	38	COG1359	Quinol monooxygenase YgiN	100
649916169	313	29.67	1	296	1	293	4.0e-36	145	COG0583	DNA-binding transcriptional regulator, LysR family	297
649916175	271	29.29	1	260	1	296	2.0e-29	123	COG0451	Nucleoside-diphosphate-sugar epimerase	314
649916176	154	25.2	24	146	7	126	5.0e-13	67.3	COG1846	DNA-binding transcriptional regulator, MarR family	126
649916177	244	31.75	1	244	1	240	1.0e-37	150	COG2071	Gamma-glutamyl-gamma-aminobutyrate hydrolase PuuD (putrescine degradation), contains GATase1-like domain	243
649916178	196	40.51	11	165	12	169	8.0e-31	126	COG0357	16S rRNA G527 N7-methylase RsmG (former glucose-inhibited division protein B)	215
649916179	280	43.7	1	252	1	253	3.0e-57	215	COG1192	Cellulose biosynthesis protein BcsQ	259
649916180	302	34.68	40	286	1	234	8.0e-31	127	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
649916183	176	21.79	10	160	3	147	5.0e-16	77.8	COG4899	Uncharacterized protein	166
649916186	811	17.75	19	413	4	419	1.0e-18	89.4	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
649916187	98	40.86	5	97	2	94	4.0e-13	66.3	COG0776	Bacterial nucleoid DNA-binding protein	94
649916188	241	31.16	15	227	7	220	3.0e-31	128	COG5587	Uncharacterized conserved protein, DUF2461 family	228
649916189	418	20.79	39	414	1	369	3.0e-24	106	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
649916190	316	42.61	33	313	35	313	3.0e-59	222	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
649916191	307	31.67	5	298	1	293	4.0e-32	132	COG0583	DNA-binding transcriptional regulator, LysR family	297
649916192	377	29.86	1	344	1	337	4.0e-31	129	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
649916193	526	28.68	18	405	3	380	4.0e-41	162	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
649916195	296	22.67	1	280	1	294	1.0e-25	110	COG0451	Nucleoside-diphosphate-sugar epimerase	314
649916198	347	27.73	2	308	7	357	1.0e-23	104	COG3240	Phospholipase/lecithinase/hemolysin	370
649916200	138	42.75	1	137	1	137	2.0e-40	158	COG0432	Thiamin phosphate synthase YjbQ, UPF0047 family	137
649916202	160	35.63	2	85	20	106	9.0e-12	63	COG0607	Rhodanese-related sulfurtransferase	110
649916203	116	36.7	1	108	2	110	5.0e-09	53.3	COG0640	DNA-binding transcriptional regulator, ArsR family	110
649916204	460	30.3	16	216	29	249	2.0e-17	84.1	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
649916207	835	39.18	11	834	110	933	0.0e+00	896	COG0178	Excinuclease UvrABC ATPase subunit	935
649916208	496	33.59	14	268	2	260	1.0e-42	167	COG0467	RecA-superfamily ATPase, KaiC/GvpD/RAD55 family	260
649916212	190	31.84	1	179	3	175	4.0e-21	94.8	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
649916215	237	25	12	234	5	221	3.0e-17	82.4	COG4912	3-methyladenine DNA glycosylase AlkD	222
649916217	194	29.2	1	133	2	137	1.0e-12	66.2	COG1896	5'-deoxynucleotidase YfbR and related HD superfamily hydrolases	193
649916221	305	37.88	1	304	1	326	5.0e-47	181	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
649916222	158	25.85	9	144	4	147	2.0e-07	48.6	COG4276	Ligand-binding SRPBCC domain	153
649916223	363	24.57	21	359	3	340	2.0e-32	133	COG0673	Predicted dehydrogenase	342
649916224	143	32.61	1	136	1	128	2.0e-20	91.1	COG3744	PIN domain nuclease, a component of toxin-antitoxin system (PIN domain)	130
649916228	676	49.49	85	672	12	583	0.0e+00	698	COG0441	Threonyl-tRNA synthetase	589
649916230	386	34.36	4	384	2	388	2.0e-84	306	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
649916231	401	23.47	18	398	21	402	5.0e-63	235	COG4320	Uncharacterized conserved protein, DUF2252 family	410
649916232	220	29.33	3	209	1	207	2.0e-30	125	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
649916234	382	50	34	378	8	352	9.0e-104	370	COG2805	Tfp pilus assembly protein PilT, pilus retraction ATPase	353
649916235	315	33.22	29	315	2	299	3.0e-43	169	COG1893	Ketopantoate reductase	307
649916236	103	29	1	100	2	96	1.0e-05	41.6	COG3668	Plasmid stabilization system protein ParE	98
649916238	259	36	10	257	4	250	1.0e-40	160	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
649916240	395	31.49	58	389	66	403	4.0e-48	185	COG0793	C-terminal processing protease CtpA/Prc, contains a PDZ domain	406
649916241	113	37.11	6	102	4	100	2.0e-14	71	COG1695	DNA-binding transcriptional regulator, PadR family	138
649916242	892	19.1	504	890	10	417	4.0e-14	74	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
649916243	898	22.49	67	684	13	610	7.0e-36	146	COG4354	Uncharacterized protein, contains GBA2_N and DUF608 domains	721
649916244	186	18.07	9	171	15	179	4.0e-07	48.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
649916247	397	32.98	20	397	1	364	1.0e-63	237	COG0592	DNA polymerase III sliding clamp (beta) subunit, PCNA homolog	364
649916255	137	30.97	25	136	6	114	3.0e-10	58	COG4679	Phage-related protein	116
649916257	418	24.38	33	412	42	438	4.0e-25	109	COG2271	Sugar phosphate permease	448
649916258	198	38.92	1	198	1	201	4.0e-46	177	COG0632	Holliday junction resolvasome RuvABC DNA-binding subunit	201
649916260	517	38.89	95	516	150	551	2.0e-87	317	COG1626	Neutral trehalase	558
649916261	585	37.31	35	537	1	495	4.0e-85	309	COG0366	Glycosidase	505
649916262	487	34.67	1	487	2	497	2.0e-95	343	COG1070	Sugar (pentulose or hexulose) kinase	502
649916264	470	28.12	2	463	4	460	2.0e-76	280	COG2407	L-fucose isomerase or related protein	470
649916266	573	24.04	18	533	4	492	9.0e-40	158	COG0591	Na+/proline symporter	493
649916269	286	30.92	33	276	3	258	4.0e-35	141	COG3622	Hydroxypyruvate isomerase	260
649916270	448	18.25	20	427	19	384	4.0e-11	63.3	COG2814	Predicted arabinose efflux permease, MFS family	394
649916271	295	32.16	1	280	1	276	5.0e-34	138	COG0583	DNA-binding transcriptional regulator, LysR family	297
649916272	1057	30.15	2	1037	1	1006	0.0e+00	674	COG0841	Multidrug efflux pump subunit AcrB	1009
649916273	429	30.1	51	428	1	372	1.0e-32	134	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
649916274	486	38.3	15	484	1	452	1.0e-61	230	COG1538	Outer membrane protein TolC	457
649916275	288	50.7	5	286	1	279	4.0e-90	324	COG0157	Nicotinate-nucleotide pyrophosphorylase	280
649916276	513	47.18	1	506	7	510	0.0e+00	545	COG0029	Aspartate oxidase	518
649916277	437	37.22	68	427	12	320	4.0e-93	335	COG0379	Quinolinate synthase	324
649916278	185	52.41	1	180	1	187	3.0e-54	204	COG2156	K+-transporting ATPase, c chain	190
649916279	677	73.72	1	677	1	681	0.0e+00	1052	COG2216	High-affinity K+ transport system, ATPase chain B	681
649916280	587	61.35	5	581	4	560	0.0e+00	716	COG2060	K+-transporting ATPase, A chain	560
649916283	234	43.04	3	227	1	229	2.0e-52	199	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
649916286	418	15.85	22	399	3	458	1.0e-16	81.7	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
649916290	326	44.06	1	323	1	345	1.0e-106	379	COG1089	GDP-D-mannose dehydratase	345
649916291	401	21.3	20	401	16	380	2.0e-26	113	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649916292	333	19.81	33	328	4	304	3.0e-16	79.4	COG1216	Glycosyltransferase, GT2 family	305
649916293	377	28.39	1	373	1	376	4.0e-35	142	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649916294	412	20.06	79	412	55	380	8.0e-16	78.5	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
649916295	503	22.07	63	496	1	418	1.0e-18	88.2	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
649916296	449	46.48	4	449	1	454	0.0e+00	476	COG0486	tRNA U34 5-carboxymethylaminomethyl modifying GTPase MnmE/TrmE	454
649916298	597	32.23	264	590	7	313	5.0e-55	209	COG0706	Membrane protein insertase Oxa1/YidC/SpoIIIJ, required for the localization of integral membrane proteins	314
649916299	73	42.47	1	73	6	74	2.0e-17	81.2	COG0759	Membrane-anchored protein YidD, putatitve component of membrane protein insertase Oxa1/YidC/SpoIIIJ	92
649916300	154	27.42	32	154	3	116	2.0e-10	58.8	COG0594	RNase P protein component	117
649916301	51	60.47	3	45	2	44	3.0e-03	33.3	COG0230	Ribosomal protein L34	44
650638552	160	28.3	7	109	5	107	1.0e-08	52.9	COG1943	REP element-mobilizing transposase RayT	136
650638555	89	31.87	1	89	2	92	3.0e-07	47	COG3668	Plasmid stabilization system protein ParE	98
650638556	104	39.24	1	79	1	78	2.0e-12	63.7	COG3077	Antitoxin component of the RelBE or YafQ-DinJ toxin-antitoxin module	88
650638564	238	34.92	1	179	2	190	4.0e-30	125	COG1801	Uncharacterized conserved protein YecE, DUF72 family	263
650638604	312	26.09	6	286	26	291	4.0e-17	82.6	COG4974	Site-specific recombinase XerD	300
650638609	909	13.09	97	441	4	340	1.0e-14	75.9	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
650638616	407	27.4	23	311	4	276	1.0e-21	98.3	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
650638633	288	30.6	11	239	32	255	2.0e-32	133	COG0706	Membrane protein insertase Oxa1/YidC/SpoIIIJ, required for the localization of integral membrane proteins	314
650638639	134	40.57	19	123	12	116	3.0e-16	77.2	COG4679	Phage-related protein	116
650638643	371	18.34	52	339	35	298	9.0e-08	51.8	COG3547	Transposase	303
