gene_oid	gene_length	percent_identity	query_start	query_end	subj_start	subj_end	evalue	bit_score	cog_id	cog_name	cog_length
2918742440	233	58.12	1	232	165	393	9.6e-118	387.8	COG0050	Translation elongation factor EF-Tu, a GTPase	394
2918742442	127	90.41	49	120	6	71	3.3e-20	66.3	COG0690	Preprotein translocase subunit SecE	73
2918742443	203	97.27	28	203	4	181	8.4e-64	209.2	COG0250	Transcription antitermination factor NusG	178
2918742444	143	99.29	2	143	1	140	1.5e-63	207.6	COG0080	Ribosomal protein L11	141
2918742445	232	99.57	1	227	1	229	1.9e-92	303.6	COG0081	Ribosomal protein L1	228
2918742446	177	94.32	1	170	3	168	2.6e-48	158.5	COG0244	Ribosomal protein L10	175
2918742447	125	100	1	125	1	125	1.4e-48	159.2	COG0222	Ribosomal protein L7/L12	124
2918742448	1374	99.45	5	1374	3	1082	0.0e+00	1459.5	COG0085	DNA-directed RNA polymerase, beta subunit/140 kD subunit	1060
2918742449	1409	3.58	881	982	420	448	0.0e+00	10.9	COG0086	DNA-directed RNA polymerase, beta' subunit/160 kD subunit	808
2918742449	1409	8.01	1234	1387	689	753	0.0e+00	19.9	COG0086	DNA-directed RNA polymerase, beta' subunit/160 kD subunit	808
2918742449	1409	99.63	12	852	3	810	0.0e+00	956.5	COG0086	DNA-directed RNA polymerase, beta' subunit/160 kD subunit	808
2918742451	442	99.16	89	441	3	357	5.6e-91	300.1	COG0144	16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family	355
2918742453	776	97.75	16	761	13	708	0.0e+00	579.7	COG5000	Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation	712
2918742454	233	13.92	138	231	400	464	2.0e-50	36.3	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2918742454	233	26.77	1	135	4	128	2.0e-50	128.7	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2918742456	433	81.88	6	375	78	425	3.5e-112	370.3	COG0840	Methyl-accepting chemotaxis protein	408
2918742457	163	92.99	5	141	11	156	2.6e-14	47.9	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
2918742458	209	21.69	124	200	227	290	1.3e-11	19.8	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918742458	209	35.93	3	134	25	130	1.3e-11	19.8	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918742459	127	88.64	1	126	9	125	2.0e-36	119.1	COG2343	Uncharacterized conserved protein, DUF427 family	132
2918742460	370	95.91	11	369	4	331	4.0e-55	181.6	COG0668	Small-conductance mechanosensitive channel	316
2918742462	541	99.27	1	536	2	547	0.0e+00	601.8	COG0459	Chaperonin GroEL (HSP60 family)	524
2918742463	106	98.96	1	96	1	95	1.0e-37	122.8	COG0234	Co-chaperonin GroES (HSP10)	96
2918742465	364	98.78	3	345	4	407	1.5e-35	116.1	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918742466	716	93.5	38	689	42	645	0.0e+00	466.6	COG3408	Glycogen debranching enzyme (alpha-1,6-glucosidase)	641
2918742467	368	97.73	48	368	3	304	2.3e-86	283.9	COG3386	Sugar lactone lactonase YvrE	307
2918742468	144	95.09	1	120	8	162	4.5e-27	89.8	COG0517	CBS domain	117
2918742470	732	87.82	13	727	86	727	0.0e+00	803.9	COG2217	Cation transport ATPase	713
2918742471	507	98.13	4	473	3	474	6.5e-118	389.2	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
2918742472	328	97.49	6	327	7	317	9.1e-89	292.2	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918742473	304	97.01	9	304	6	297	5.9e-55	181.6	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918742474	125	94.68	1	93	3	91	7.9e-29	93.9	COG0776	Bacterial nucleoid DNA-binding protein	94
2918742475	302	97.67	6	302	3	296	1.0e-66	220.3	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918742476	319	68.37	11	296	49	275	2.0e-24	80.9	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
2918742477	989	64.71	476	987	215	643	4.4e-111	366.2	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2918742478	801	59.5	119	490	99	242	3.9e-24	35.2	COG2202	PAS domain	232
2918742478	801	66.53	443	614	81	241	3.9e-24	52.2	COG2202	PAS domain	232
2918742478	801	97.27	601	781	5	182	2.7e-54	177.8	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2918742479	641	77.92	56	506	84	390	1.5e-63	209.1	COG0642	Signal transduction histidine kinase	336
2918742480	282	94.53	24	281	4	262	4.4e-71	233.7	COG0171	NH3-dependent NAD+ synthetase	268
2918742481	389	67.51	151	389	102	315	1.2e-55	183.4	COG2829	Outer membrane phospholipase A	317
2918742483	701	99.55	3	678	1	668	0.0e+00	617.4	COG0210	Superfamily I DNA or RNA helicase	655
2918742484	337	96.81	1	337	4	306	8.3e-44	143.5	COG0679	Predicted permease	311
2918742487	704	14.71	3	136	6	113	0.0e+00	36.9	COG1198	Primosomal protein N' (replication factor Y) - superfamily II helicase	730
2918742487	704	73.57	117	704	195	734	0.0e+00	613.1	COG1198	Primosomal protein N' (replication factor Y) - superfamily II helicase	730
2918742488	365	98.02	1	362	6	351	1.8e-128	423.1	COG0407	Uroporphyrinogen-III decarboxylase	352
2918742489	311	98.01	12	309	1	295	1.1e-46	154.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918742490	239	99.63	1	237	1	267	6.2e-42	138.5	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918742491	457	47.26	252	455	9	189	1.6e-34	22.1	COG0477	MFS family permease	338
2918742491	457	82.25	32	312	5	319	1.6e-34	98.1	COG0477	MFS family permease	338
2918742492	230	84.08	49	197	4	135	1.3e-07	22.9	COG1225	Peroxiredoxin	157
2918742493	704	70.05	215	704	179	606	9.3e-102	336.2	COG4232	Thiol:disulfide interchange protein	569
2918742494	249	96.3	1	248	1	234	7.5e-72	236.3	COG2872	Ser-tRNA(Ala) deacylase AlaX (editing enzyme)	241
2918742495	451	98.31	8	451	6	411	9.5e-130	427.8	COG2133	Glucose/arabinose dehydrogenase, beta-propeller fold	399
2918742496	188	93.58	4	187	6	180	2.4e-34	113.5	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
2918742497	336	96.68	1	335	11	330	9.9e-81	266.3	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2918742498	305	98.01	4	300	2	296	3.6e-65	215.2	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918742499	265	98.51	3	262	2	265	2.7e-58	192.2	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918742501	427	71.68	6	414	13	374	6.1e-72	237.2	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
2918742502	679	31.34	207	320	130	213	2.8e-22	19.4	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
2918742502	679	38.06	40	146	3	104	2.8e-22	52.5	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
2918742504	275	95.18	11	266	9	245	6.7e-61	200.2	COG1402	 Creatinine amidohydrolase/Fe(II)-dependent formamide hydrolase involved in riboflavin and F420 biosynthesis	250
2918742505	325	92.2	1	324	9	327	1.0e-84	279.1	COG1171	Threonine dehydratase	347
2918742506	210	98.56	2	209	2	206	1.3e-55	182.4	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
2918742508	307	98.97	1	307	3	291	7.8e-81	259.6	COG0384	Predicted epimerase YddE/YHI9, PhzF superfamily	291
2918742509	213	92.56	2	211	3	201	2.1e-47	156.3	COG0625	Glutathione S-transferase	211
2918742510	223	98.08	2	208	2	205	1.1e-52	172.8	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
2918742511	210	45.54	2	187	41	188	1.7e-17	57.9	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
2918742512	400	85.75	4	388	64	454	8.0e-121	398.4	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
2918742513	318	97.01	8	305	4	295	5.2e-37	122.1	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918742514	199	98.08	1	199	1	204	9.0e-32	104.5	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
2918742515	471	97.15	6	471	4	446	3.1e-98	324.1	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
2918742516	247	48.62	50	158	39	91	2.1e-05	19.6	COG2058	Ribosomal protein L12E/L44/L45/RPP1/RPP2	109
2918742517	426	92.03	6	426	29	386	4.5e-34	109.4	COG4398	Small ligand-binding sensory domain FIST	389
2918742518	433	96.65	1	431	5	379	2.7e-67	222.1	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918742521	360	99.14	1	351	3	349	0.0e+00	536.3	COG1088	dTDP-D-glucose 4,6-dehydratase	340
2918742522	296	99.29	1	296	1	280	2.6e-101	333	COG1091	dTDP-4-dehydrorhamnose reductase	281
2918742523	300	98.97	9	297	1	288	3.2e-123	404.9	COG1209	dTDP-glucose pyrophosphorylase	286
2918742524	182	95.48	2	177	7	175	3.2e-71	232.9	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase or related enzyme	173
2918742525	370	97.31	8	368	9	406	3.7e-32	107	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918742526	416	99.51	2	391	2	408	9.5e-32	105.7	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918742527	324	97.82	10	318	3	316	6.6e-67	220.7	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2918742529	342	52.32	8	318	147	360	1.3e-09	32.9	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918742531	297	96.57	2	289	3	312	2.6e-54	179.3	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2918742532	345	99.42	1	342	1	342	0.0e+00	528.5	COG1089	GDP-D-mannose dehydratase	345
2918742533	1349	62.84	982	1343	142	398	1.1e-17	58.7	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918742533	1349	73.48	413	644	5	234	5.0e-34	111.1	COG1216	Glycosyltransferase, GT2 family	305
2918742534	249	93.23	1	247	2	235	2.4e-86	283.8	COG1134	ABC-type polysaccharide/polyol phosphate transport system, ATPase component	249
2918742535	268	98.87	8	268	4	265	2.1e-67	221.7	COG1682	ABC-type polysaccharide/polyol phosphate export permease	263
2918742536	444	90.75	1	307	32	335	4.6e-96	316.3	COG0836	Mannose-1-phosphate guanylyltransferase	333
2918742536	444	96.12	316	442	5	128	5.0e-34	110.8	COG0662	Mannose-6-phosphate isomerase, cupin superfamily	127
2918742537	626	73.48	330	580	2	231	7.4e-27	87.6	COG1216	Glycosyltransferase, GT2 family	305
2918742538	334	29.25	5	242	4	108	1.6e-12	41.5	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
2918742539	353	60.45	17	343	2	218	2.9e-27	91.2	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
2918742540	677	91.52	9	381	11	366	1.5e-99	327.8	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
2918742541	252	76.68	8	246	3	242	5.9e-25	82.5	COG1216	Glycosyltransferase, GT2 family	305
2918742542	365	96.93	1	336	7	322	2.6e-49	162.9	COG0472	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase	319
2918742543	297	99.62	28	296	1	264	2.7e-101	332.7	COG0548	Acetylglutamate kinase	265
2918742545	345	99.39	4	338	2	328	0.0e+00	439.7	COG1087	UDP-glucose 4-epimerase	329
2918742546	183	86.12	1	183	17	196	2.0e-17	59.3	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918742547	507	96.21	1	492	13	494	0.0e+00	724.7	COG0753	Catalase	496
2918742548	200	97.12	1	200	5	206	4.4e-68	223.8	COG5588	Uncharacterized protein	207
2918742549	259	93.99	1	259	14	279	1.8e-79	261.6	COG5486	Predicted metal-binding membrane protein	283
2918742550	295	95.68	12	294	9	296	2.4e-29	97	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918742551	352	96.85	2	352	8	345	9.6e-103	338.3	COG2055	Malate/lactate/ureidoglycolate dehydrogenase, LDH2 family	349
2918742552	508	14.32	8	102	177	233	0.0e+00	5.8	COG2721	Altronate dehydratase	381
2918742552	508	99.5	100	508	3	398	0.0e+00	538.1	COG2721	Altronate dehydratase	381
2918742553	464	99.74	43	464	1	378	0.0e+00	491	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
2918742554	185	84.75	19	184	15	164	9.6e-34	110.7	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
2918742555	331	90.36	4	330	5	304	3.3e-98	323.5	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
2918742556	237	95.02	2	236	5	233	5.1e-61	200.5	COG2186	DNA-binding transcriptional regulator, FadR family	241
2918742557	244	99.63	1	243	1	267	5.5e-61	201	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918742558	248	99.25	4	247	2	267	3.9e-68	224.5	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918742559	282	96.34	10	281	8	270	1.2e-86	285.3	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
2918742560	260	97.07	1	239	7	238	2.5e-51	168.6	COG2188	DNA-binding transcriptional regulator, GntR family	236
2918742561	400	94.54	8	394	9	354	1.2e-46	153.9	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918742562	290	97.67	3	290	3	296	5.1e-71	234.2	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2918742563	326	95.36	3	316	9	316	1.8e-72	238.7	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918742564	253	99.21	1	238	2	253	4.1e-87	285.6	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2918742565	236	99.16	2	236	2	236	6.0e-90	295.1	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2918742566	321	97.18	4	319	7	316	2.9e-84	277.3	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918742567	429	99.3	10	428	3	428	0.0e+00	437.5	COG0065	Homoaconitase/3-isopropylmalate dehydratase large subunit	423
2918742568	174	91.71	4	174	10	186	3.4e-38	125.9	COG0066	3-isopropylmalate dehydratase small subunit	191
2918742569	447	91.01	7	438	9	423	1.5e-40	133.5	COG2079	2-methylcitrate dehydratase PrpD	453
2918742570	322	97.18	2	320	7	316	5.3e-100	329	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918742571	562	96.99	4	561	2	549	0.0e+00	479	COG0146	N-methylhydantoinase B/oxoprolinase/acetone carboxylase, alpha subunit	563
2918742572	684	99.56	6	684	3	678	0.0e+00	619.5	COG0145	N-methylhydantoinase A/oxoprolinase/acetone carboxylase, beta subunit	674
2918742573	198	96.6	1	198	3	201	2.1e-36	120.2	COG1335	Nicotinamidase-related amidase	205
2918742574	471	12.72	360	471	347	418	2.2e-37	18	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
2918742574	471	47.88	17	318	7	277	2.2e-37	110	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
2918742575	287	94.5	2	286	10	284	5.4e-89	292.5	COG2513	2-Methylisocitrate lyase and related enzymes, PEP mutase family	289
2918742576	295	97.67	3	295	2	295	1.3e-58	193.8	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918742577	252	99.19	1	252	3	246	1.0e-84	278.7	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
2918742578	232	87.08	6	229	4	185	1.5e-16	56.2	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918742579	598	96.99	12	464	9	395	7.9e-99	325.7	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918742580	144	75.15	1	144	41	164	8.6e-15	49.3	COG4731	Uncharacterized conserved protein, DUF2147 family	162
2918742581	799	16.11	344	485	196	248	1.1e-87	16.3	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
2918742581	799	85.28	481	774	23	248	2.5e-38	125.8	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918742581	799	87.23	4	342	2	288	1.1e-87	270.8	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
2918742582	139	88.37	1	120	10	123	7.4e-40	130.4	COG2852	Very-short-patch-repair endonuclease	129
2918742583	400	99.75	6	400	2	394	0.0e+00	451.9	COG0183	Acetyl-CoA acetyltransferase	392
2918742584	301	96.44	1	283	9	279	1.3e-58	193.1	COG4757	Predicted alpha/beta hydrolase	281
2918742585	277	93.45	4	277	12	282	9.2e-06	18.4	COG1946	Acyl-CoA thioesterase	289
2918742586	249	93.28	1	243	1	250	5.0e-34	112.7	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918742587	197	96.55	1	197	6	201	1.7e-72	237.9	COG3917	2-hydroxychromene-2-carboxylate isomerase	203
2918742588	254	98.49	1	251	5	265	8.8e-68	223.1	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918742589	371	92.9	3	358	11	350	3.2e-32	106.4	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918742590	141	77.07	7	141	11	131	1.5e-42	139.4	COG1607	Acyl-CoA hydrolase	157
2918742591	614	99.8	110	605	1	496	0.0e+00	741.8	COG5265	ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components	497
2918742592	312	88.69	3	312	30	319	2.8e-81	267.4	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
2918742593	480	99.38	3	477	3	480	1.4e-124	411.2	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
2918742594	328	91.36	1	298	1	275	2.9e-48	159.6	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918742595	483	98.09	2	470	3	464	0.0e+00	699.2	COG1027	Aspartate ammonia-lyase	471
2918742596	300	96.47	1	272	5	277	4.4e-49	161.8	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918742597	243	92.54	4	232	16	226	9.1e-61	199.9	COG0765	ABC-type amino acid transport system, permease component	222
2918742598	229	92.98	1	229	15	226	6.5e-63	207	COG0765	ABC-type amino acid transport system, permease component	222
2918742599	249	99.17	4	247	2	241	6.4e-107	350.7	COG1126	ABC-type polar amino acid transport system, ATPase component	240
2918742600	312	99.36	1	312	2	312	5.1e-106	349.1	COG1957	Inosine-uridine nucleoside N-ribohydrolase	311
2918742601	345	96.69	1	342	9	329	3.7e-87	287.2	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
2918742602	432	98.68	51	431	3	376	2.1e-108	356.7	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
2918742603	194	83.62	22	189	10	157	8.2e-30	98	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
2918742604	337	95.92	13	335	11	316	2.3e-85	280.9	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918742605	647	96.48	37	586	13	560	3.0e-85	281	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2918742606	330	97.81	9	329	6	317	8.2e-86	282.5	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918742607	402	98.75	1	402	6	401	0.0e+00	467.6	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2918742608	270	99.25	1	259	3	265	4.7e-65	214.1	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918742609	380	92.23	1	375	3	370	1.1e-69	230	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918742610	402	98.75	1	402	1	394	1.1e-88	292.6	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918742611	396	99.49	1	395	1	392	4.6e-115	379.3	COG0183	Acetyl-CoA acetyltransferase	392
2918742612	711	25.23	612	703	188	270	8.1e-100	20.5	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
2918742612	711	95.85	9	295	6	259	2.0e-61	201.5	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918742612	711	96.66	303	638	4	321	8.1e-100	312.6	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
2918742613	310	98.67	1	302	1	297	2.7e-65	215.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918742615	172	88.69	9	171	3	151	4.0e-43	141.3	COG3194	Ureidoglycolate hydrolase (allantoin degradation)	168
2918742616	120	88.43	3	120	7	113	5.6e-18	59.5	COG3070	Transcriptional regulator of competence genes, TfoX/Sxy family	121
2918742617	393	83.37	15	392	69	469	5.5e-80	263.4	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
2918742618	340	99.08	12	329	2	323	1.0e-117	387.3	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
2918742619	345	96.56	11	319	2	310	1.6e-109	360.6	COG4608	ABC-type oligopeptide transport system, ATPase component	309
2918742620	303	93.62	13	303	16	294	6.9e-86	282.4	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2918742621	317	99.06	1	317	1	315	1.3e-97	321.6	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2918742622	552	95.16	3	549	14	563	6.7e-77	254.1	COG0747	ABC-type transport system, periplasmic component	556
2918742623	343	99.42	1	343	2	343	0.0e+00	504.4	COG0418	Dihydroorotase	344
2918742625	273	23.01	64	117	43	68	9.2e-04	7.8	COG4634	Predicted nuclease, contains PIN domain, potential toxin-antitoxin system component	113
2918742625	273	30.09	1	48	67	100	9.2e-04	3.9	COG4634	Predicted nuclease, contains PIN domain, potential toxin-antitoxin system component	113
2918742627	291	94.55	1	291	12	306	1.9e-68	225.7	COG0501	Zn-dependent protease with chaperone function	302
2918742628	269	55.45	71	264	18	134	4.4e-17	57.3	COG3109	sRNA-binding protein	208
2918742629	214	94.05	9	209	7	180	3.4e-44	145.1	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
2918742630	546	98.97	5	545	2	482	0.0e+00	538.4	COG2509	Uncharacterized FAD-dependent dehydrogenase	486
2918742631	306	99.01	2	301	3	301	4.9e-116	381.5	COG0031	Cysteine synthase	300
2918742633	159	82.71	17	149	18	127	1.8e-21	71.1	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918742634	692	97.08	6	687	6	671	1.1e-88	292.6	COG1289	Uncharacterized membrane protein YccC	674
2918742636	311	93.18	3	306	12	339	2.3e-85	274.4	COG1566	Multidrug resistance efflux pump	352
2918742637	489	98.26	13	479	3	454	2.3e-90	298.2	COG1538	Outer membrane protein TolC	457
2918742639	237	95.12	8	237	3	236	5.9e-31	101.8	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
2918742640	553	77.91	8	216	13	146	1.1e-15	51.9	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2918742640	553	84.62	280	548	19	238	8.3e-35	114.5	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2918742641	347	95.92	18	345	12	317	4.4e-80	263.6	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918742643	316	98.34	13	313	4	299	2.7e-42	140.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918742644	362	96.24	12	355	8	340	1.4e-51	170	COG1816	Adenosine deaminase	345
2918742645	329	96.87	5	328	6	314	6.2e-74	243.5	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918742646	329	96.35	15	306	6	295	9.5e-42	137.7	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918742647	400	91.75	3	400	23	411	1.0e-56	186.8	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
2918742651	788	98.48	1	594	5	523	0.0e+00	490.2	COG3511	Phospholipase C	527
2918742655	317	82.58	190	317	17	125	1.2e-28	93.7	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918742656	96	87.88	1	95	2	88	7.1e-13	43	COG1359	Quinol monooxygenase YgiN	100
2918742658	313	98.01	7	304	2	296	2.6e-53	176.3	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918742660	219	94.58	4	213	9	200	1.2e-52	172.9	COG3917	2-hydroxychromene-2-carboxylate isomerase	203
2918742661	294	99.63	3	290	1	270	1.9e-95	313.9	COG0253	Diaminopimelate epimerase	272
2918742662	221	99.08	1	221	2	217	4.6e-48	158.3	COG3159	Uncharacterized conserved protein YigA, DUF484 family	218
2918742663	212	67.97	3	194	31	187	2.0e-16	54.7	COG1434	Uncharacterized SAM-binding protein YcdF, DUF218 family	223
2918742664	339	96.66	5	321	9	297	2.4e-104	343.3	COG4973	Site-specific recombinase XerC	299
2918742665	406	98.73	4	403	2	389	2.8e-106	350.1	COG1092	23S rRNA G2069 N7-methylase RlmK or C1962 C5-methylase RlmI	393
2918742666	350	99.39	4	350	1	324	2.1e-105	345	COG0523	GTPase, G3E family	323
2918742667	493	12.66	2	80	3	63	1.0e-14	9.3	COG5339	Uncharacterized conserved protein YdgA, DUF945 family	479
2918742667	493	29.46	303	491	326	467	1.0e-14	13.4	COG5339	Uncharacterized conserved protein YdgA, DUF945 family	479
2918742667	493	32.37	96	261	86	241	1.0e-14	22.8	COG5339	Uncharacterized conserved protein YdgA, DUF945 family	479
2918742668	207	99.17	88	207	1	119	2.4e-38	125.8	COG1734	RNA polymerase-binding transcription factor DksA	120
2918742669	548	81.82	448	544	14	94	5.6e-04	13	COG3113	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, MlaB component, contains STAS domain	99
2918742670	181	97.75	3	181	2	175	1.5e-86	283	COG5405	ATP-dependent protease HslVU (ClpYQ), peptidase subunit	178
2918742671	442	99.55	1	442	3	444	0.0e+00	701	COG1220	ATP-dependent protease HslVU (ClpYQ), ATPase subunit	444
2918742672	125	86.3	1	125	18	143	4.4e-33	108.7	COG2001	MraZ, DNA-binding transcriptional regulator and inhibitor of RsmH methyltransferase activity	146
2918742673	308	98.1	1	306	5	313	5.3e-107	352.6	COG0275	16S rRNA C1402 N4-methylase RsmH	314
2918742674	115	81.73	1	86	19	103	8.0e-22	71.7	COG3116	Cell division protein FtsL, interacts with FtsB, FtsL and FtsQ	105
2918742675	582	97.47	14	567	14	629	0.0e+00	435.9	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
2918742676	517	22.31	4	134	18	125	0.0e+00	72	COG0769	UDP-N-acetylmuramyl tripeptide synthase	475
2918742676	517	73.14	148	514	129	482	0.0e+00	370	COG0769	UDP-N-acetylmuramyl tripeptide synthase	475
2918742677	475	98.68	6	465	5	452	3.8e-128	422.4	COG0770	UDP-N-acetylmuramyl pentapeptide synthase	451
2918742678	390	98.77	21	390	2	323	3.5e-108	355.6	COG0472	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase	319
2918742679	705	23.11	1	134	4	107	3.5e-130	55.1	COG0771	UDP-N-acetylmuramoylalanine-D-glutamate ligase	448
2918742679	705	75.78	256	685	109	449	3.5e-130	372.5	COG0771	UDP-N-acetylmuramoylalanine-D-glutamate ligase	448
2918742680	432	95.29	44	431	13	376	1.7e-114	376.9	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
2918742681	354	99.16	4	354	3	357	1.2e-109	361.3	COG0707	UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase	357
2918742682	484	98.48	1	468	4	457	0.0e+00	549.1	COG0773	UDP-N-acetylmuramate-alanine ligase	459
2918742683	323	99.37	8	315	2	317	2.2e-98	323.8	COG1181	D-alanine-D-alanine ligase and related ATP-grasp enzymes	317
2918742684	262	84.5	3	252	27	255	8.6e-38	124.6	COG1589	Cell division septal protein FtsQ	269
2918742685	409	87.56	1	402	4	383	0.0e+00	455.8	COG0849	Cell division ATPase FtsA	418
2918742686	407	93.1	3	340	3	326	1.1e-118	390.9	COG0206	Cell division GTPase FtsZ	338
2918742687	307	96.68	1	304	3	293	2.6e-120	395.5	COG0774	UDP-3-O-acyl-N-acetylglucosamine deacetylase	300
2918742689	318	95.68	12	318	5	292	1.0e-41	138.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918742690	440	94.22	26	434	13	403	8.0e-83	272.8	COG0112	Glycine/serine hydroxymethyltransferase	413
2918742691	182	95.03	4	166	1	153	4.9e-54	176.9	COG0817	Holliday junction resolvasome RuvABC endonuclease subunit	160
2918742692	329	99.34	12	328	2	302	1.7e-74	245.8	COG4589	Predicted CDP-diglyceride synthetase/phosphatidate cytidylyltransferase	303
2918742693	301	62.45	2	299	61	223	4.0e-17	52.5	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
2918742695	247	27.91	1	246	56	254	2.8e-63	208.1	COG0744	Membrane carboxypeptidase (penicillin-binding protein)	661
2918742696	285	96.83	1	283	7	281	1.8e-75	248.2	COG0169	Shikimate 5-dehydrogenase	283
2918742697	283	55.11	6	275	123	273	5.0e-12	40.3	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
2918742698	686	15.19	488	620	543	650	2.2e-57	53.5	COG0557	Exoribonuclease R	706
2918742698	686	30.94	109	486	259	478	2.2e-57	133.2	COG0557	Exoribonuclease R	706
2918742699	197	96.39	4	196	3	189	2.8e-52	172	COG3150	Predicted esterase YcpF, UPF0227 family	191
2918742700	242	98.58	14	239	3	210	1.7e-43	143.1	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918742701	597	68.27	269	594	110	365	7.5e-30	99.1	COG4585	Signal transduction histidine kinase	365
2918742702	384	96.34	9	384	9	376	2.6e-112	369.8	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
2918742703	486	98.68	25	485	6	455	0.0e+00	512.2	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
2918742705	372	99.15	18	372	3	350	0.0e+00	533.8	COG0722	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase	351
2918742706	169	85.98	1	164	4	144	2.1e-42	139.4	COG3542	Predicted sugar epimerase, cupin superfamily	162
2918742707	467	98.26	1	463	8	460	0.0e+00	440.6	COG0773	UDP-N-acetylmuramate-alanine ligase	459
2918742709	181	89.33	24	162	14	147	9.6e-13	43.1	COG0526	Thiol-disulfide isomerase or thioredoxin	127
2918742710	153	98.64	6	153	2	146	2.6e-43	142.9	COG0511	Biotin carboxyl carrier protein	140
2918742711	449	99.56	1	448	1	448	0.0e+00	675.6	COG0439	Biotin carboxylase	449
2918742712	294	98.03	1	294	5	302	3.1e-71	234.9	COG2264	Ribosomal protein L11 methylase PrmA	300
2918742714	300	93.99	3	298	4	300	4.4e-41	135.4	COG0524	Sugar or nucleoside kinase, ribokinase family	311
2918742716	355	96.49	13	355	10	339	9.8e-102	334.9	COG0208	Ribonucleotide reductase beta subunit, ferritin-like domain	348
2918742717	971	5.77	80	154	29	72	0.0e+00	8.8	COG0209	Ribonucleotide reductase alpha subunit	696
2918742717	971	98.03	207	971	11	758	0.0e+00	604.6	COG0209	Ribonucleotide reductase alpha subunit	696
2918742718	202	68.2	13	201	3	180	1.6e-58	192.5	COG3023	N-acetyl-anhydromuramyl-L-alanine amidase AmpD	257
2918742719	518	98.29	7	509	3	461	0.0e+00	507.3	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2918742720	566	80.2	95	543	56	371	3.6e-41	135.3	COG0642	Signal transduction histidine kinase	336
2918742722	270	88.3	2	267	31	264	2.1e-46	153.3	COG4137	ABC-type uncharacterized transport system, permease component	265
2918742723	462	99.12	1	456	1	448	0.0e+00	586.2	COG0541	Signal recognition particle GTPase	451
2918742724	379	81.07	235	378	3	139	1.0e-22	74.8	COG4639	Predicted kinase	168
2918742726	671	79.76	18	670	51	637	0.0e+00	706.5	COG2943	Membrane glycosyltransferase	736
2918742728	462	98.72	2	451	5	465	0.0e+00	549.6	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2918742730	475	88.07	4	475	42	388	2.9e-53	172.9	COG0642	Signal transduction histidine kinase	336
2918742731	454	99.32	1	441	2	439	0.0e+00	526.9	COG0621	tRNA A37 methylthiotransferase MiaB	437
2918742733	403	95.9	1	379	13	386	1.7e-61	203.1	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918742734	1055	99.9	2	1027	1	1013	0.0e+00	1117	COG0841	Multidrug efflux pump subunit AcrB	1009
2918742735	215	91.87	3	210	3	194	6.8e-53	174	COG0406	Broad specificity phosphatase PhoE	208
2918742737	310	81.49	28	306	2	252	8.8e-71	233	COG0037	tRNA(Ile)-lysidine synthase TilS/MesJ	298
2918742738	124	84.3	7	121	3	104	6.4e-21	69.4	COG1539	Dihydroneopterin aldolase	121
2918742739	262	98.51	10	256	4	267	4.0e-41	135.8	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918742740	371	95.14	14	362	7	358	2.3e-89	294.2	COG1565	SAM-dependent methyltransferase, MidA family	370
2918742741	287	98.26	3	287	2	283	1.9e-84	278	COG2175	Taurine dioxygenase, alpha-ketoglutarate-dependent	286
2918742743	258	97.68	6	257	5	257	1.4e-62	205.8	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
2918742745	308	86.13	1	305	9	275	3.2e-48	157.6	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
2918742746	502	98.68	2	480	3	452	6.3e-124	408.8	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
2918742748	461	95.93	1	461	15	485	0.0e+00	495.5	COG0380	Trehalose-6-phosphate synthase	486
2918742749	640	95.67	47	635	21	617	3.7e-90	297.6	COG3387	Glucoamylase (glucan-1,4-alpha-glucosidase), GH15 family	612
2918742750	260	90.3	6	255	17	258	1.9e-52	172.6	COG1877	Trehalose-6-phosphatase	266
2918742751	419	91.57	1	404	23	402	5.6e-89	293.7	COG0617	tRNA nucleotidyltransferase/poly(A) polymerase	412
2918742752	241	100	1	241	1	218	1.4e-48	160	COG3047	Outer membrane protein W	213
2918742753	227	94.88	3	221	4	207	1.1e-35	118	COG0625	Glutathione S-transferase	211
2918742754	189	61.95	18	169	5	144	2.2e-49	162.7	COG1285	Uncharacterized membrane protein YhiD, involved in acid resistance	221
2918742755	667	98.68	348	647	3	301	7.5e-54	178.3	COG0741	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)	296
2918742756	205	96.34	15	203	5	188	1.7e-35	116.7	COG0212	5-formyltetrahydrofolate cyclo-ligase	191
2918742757	327	96.68	13	312	5	295	3.4e-65	215.3	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918742760	256	99.54	22	237	2	218	2.3e-31	103.5	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2918742762	476	99.13	10	475	3	457	0.0e+00	571.5	COG1207	Bifunctional protein GlmU, N-acetylglucosamine-1-phosphate-uridyltransferase/glucosamine-1-phosphate-acetyltransferase	460
2918742763	161	96.2	1	159	1	152	1.8e-30	100.7	COG1522	DNA-binding transcriptional regulator, Lrp family	154
2918742764	626	100	1	626	1	615	0.0e+00	726	COG0449	Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains	597
2918742765	273	91.76	9	266	15	259	4.4e-69	227	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
2918742766	282	93.4	1	281	12	280	2.3e-65	215.3	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
2918742767	342	94.18	1	341	12	367	8.8e-48	157.7	COG0687	Spermidine/putrescine-binding periplasmic protein	363
2918742768	137	86.76	5	137	18	135	2.8e-22	73.7	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
2918742769	223	83.4	1	222	1	221	1.5e-51	169.9	COG3342	Uncharacterized conserved protein, Ntn-hydrolase superfamily	265
2918742770	319	98.01	5	302	2	296	4.8e-53	175.3	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918742771	385	95.93	1	385	15	415	3.0e-73	241.9	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
2918742772	380	96.68	7	380	2	350	1.1e-126	417	COG1304	FMN-dependent dehydrogenase, includes L-lactate dehydrogenase and type II isopentenyl diphosphate isomerase	360
2918742773	416	92.6	1	414	6	418	1.6e-56	186.5	COG2072	Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD	443
2918742774	385	90.37	18	379	3	321	3.5e-128	422.3	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
2918742775	325	100	1	325	1	331	8.9e-86	282.8	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2918742776	206	98.14	2	206	1	211	1.6e-28	94.6	COG0625	Glutathione S-transferase	211
2918742777	158	97.26	10	155	3	144	9.9e-50	162.4	COG0757	3-dehydroquinate dehydratase	146
2918742778	318	85.28	15	318	45	322	5.1e-75	246.8	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
2918742779	596	96.63	27	585	5	548	3.9e-121	399.5	COG0659	Sulfate permease or related transporter, MFS superfamily	554
2918742782	89	50	21	89	2	66	2.0e-06	23.5	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918742783	92	83.16	10	92	5	83	2.1e-22	73.4	COG2827	Predicted endonuclease, GIY-YIG superfamily	95
2918742784	413	98.88	52	411	3	356	1.1e-109	361	COG1071	TPP-dependent pyruvate or acetoin dehydrogenase subunit alpha	358
2918742785	337	99.38	3	337	2	323	0.0e+00	460.3	COG0022	Pyruvate/2-oxoglutarate/acetoin dehydrogenase complex, dehydrogenase (E1) component	324
2918742786	412	99.31	2	412	2	432	4.3e-127	419.4	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
2918742787	118	92.19	51	115	2	60	6.0e-24	78.3	COG3411	(2Fe-2S) ferredoxin	64
2918742788	326	99.6	1	252	1	249	1.7e-100	330	COG1010	Precorrin-3B methylase	249
2918742789	264	96.67	1	248	3	234	1.3e-30	101.1	COG5446	Uncharacterized membrane protein, predicted cobalt tansporter CbtA	233
2918742791	134	33.96	1	132	203	310	1.1e-22	75.4	COG2073	Cobalamin biosynthesis protein CbiG	298
2918742793	266	98.72	4	242	2	233	2.2e-54	179	COG2243	Precorrin-2 methylase	234
2918742794	442	94.76	12	235	6	204	8.0e-40	130.4	COG2241	Precorrin-6B methylase 1	210
2918742794	442	98.4	242	432	2	185	5.0e-55	179.7	COG2242	Precorrin-6B methylase 2	187
2918742795	365	95.64	2	364	9	359	8.4e-93	305.5	COG1903	Cobalamin biosynthesis protein CbiD	367
2918742796	229	97.63	12	226	4	209	2.8e-57	188.2	COG2082	Precorrin isomerase	210
2918742797	315	97.61	2	254	4	248	7.1e-49	161	COG2138	Sirohydrochlorin ferrochelatase	245
2918742798	282	97.65	14	272	4	252	3.3e-85	279.8	COG2875	Precorrin-4 methylase	254
2918742801	332	96.87	9	330	7	315	6.3e-96	315.7	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918742802	354	99.14	1	354	1	345	6.9e-124	407.9	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
2918742803	309	97.01	7	305	5	296	8.0e-66	217.2	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918742804	423	90.78	1	353	29	343	2.7e-116	383	COG2951	Membrane-bound lytic murein transglycosylase B	343
2918742806	554	59.32	266	522	35	209	1.4e-05	19.9	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918742807	195	53.08	11	124	2	70	6.0e-18	59.8	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918742808	187	72.84	11	161	37	154	1.6e-10	35.7	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2918742809	326	96.01	4	302	5	293	6.6e-32	105.4	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918742810	291	97.67	1	291	1	294	3.8e-60	198.8	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918742812	357	98.08	10	356	2	308	4.9e-78	257	COG2017	Galactose mutarotase or related enzyme	308
2918742814	290	83.7	7	279	2	232	6.2e-44	145	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
2918742815	295	97.67	3	295	3	296	7.0e-69	227.4	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918742816	317	94.5	18	310	16	307	2.8e-78	257.5	COG3386	Sugar lactone lactonase YvrE	307
2918742817	258	99.25	11	258	2	267	2.2e-52	172.9	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918742818	319	97.01	13	311	3	294	1.0e-56	187.4	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918742819	483	98.12	10	481	2	471	0.0e+00	502.7	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918742820	321	92.66	1	318	5	307	3.0e-70	231.2	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
2918742821	356	97.95	3	356	6	339	0.0e+00	440.7	COG4213	ABC-type xylose transport system, periplasmic component	341
2918742822	521	98.8	4	513	5	499	0.0e+00	636.4	COG1129	ABC-type sugar transport system, ATPase component	500
2918742823	404	95.94	11	404	16	393	0.0e+00	507.7	COG4214	ABC-type xylose transport system, permease component	394
2918742824	506	97.6	3	506	7	495	0.0e+00	583	COG1129	ABC-type sugar transport system, ATPase component	500
2918742825	344	94.98	1	332	9	311	3.1e-77	254.1	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
2918742826	342	94.67	22	342	13	314	2.0e-82	271.1	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
2918742827	583	98.44	1	571	7	575	0.0e+00	613.4	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
2918742828	305	96.99	1	300	2	291	6.4e-51	167.3	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
2918742829	349	98.34	1	300	1	296	3.5e-63	208.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918742830	259	98.13	7	258	5	267	2.0e-59	195.8	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918742833	135	81.01	1	72	2	65	1.8e-01	11.5	COG4238	Outer membrane murein-binding lipoprotein Lpp	78
2918742834	855	76.86	450	854	93	464	1.4e-56	186.4	COG0769	UDP-N-acetylmuramyl tripeptide synthase	475
2918742834	855	88.36	150	465	33	313	7.1e-43	140.8	COG1181	D-alanine-D-alanine ligase and related ATP-grasp enzymes	317
2918742835	748	97.8	168	484	5	315	1.1e-25	84.4	COG1181	D-alanine-D-alanine ligase and related ATP-grasp enzymes	317
2918742836	669	98.99	60	637	4	589	0.0e+00	584.5	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
2918742838	368	92.8	13	368	14	374	1.1e-57	190.2	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
2918742839	237	94.59	4	237	3	212	4.9e-71	233.1	COG0603	7-cyano-7-deazaguanine synthase (queuosine biosynthesis)	222
2918742840	593	95.39	1	589	18	596	0.0e+00	608.4	COG4178	ABC-type uncharacterized transport system, permease and ATPase components	604
2918742841	186	95.16	1	185	7	183	6.4e-60	196.3	COG4341	Predicted HD phosphohydrolase	186
2918742843	417	51.17	224	416	8	203	7.0e-24	31.4	COG0477	MFS family permease	338
2918742843	417	59.27	14	247	8	234	7.0e-24	51.9	COG0477	MFS family permease	338
2918742844	734	99.05	1	577	4	525	0.0e+00	529.8	COG3511	Phospholipase C	527
2918742847	411	99.75	1	411	1	397	2.1e-116	383.4	COG1459	Type II secretory pathway, component PulF	397
2918742848	463	95.67	1	463	22	507	0.0e+00	553.6	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
2918742849	772	95.94	14	707	7	597	0.0e+00	457.1	COG1450	Type II secretory pathway component GspD/PulD (secretin)	587
2918742851	177	80.66	1	164	20	165	5.1e-15	50.2	COG3149	Type II secretory pathway, component PulM	181
2918742853	333	96.91	11	324	4	317	2.3e-39	129.7	COG3156	Type II secretory pathway, component PulK	323
2918742854	227	36.54	1	223	7	63	2.9e-08	28.4	COG2165	Type II secretory pathway, pseudopilin PulG	149
2918742855	124	52.56	1	120	5	86	1.0e-11	40.3	COG2165	Type II secretory pathway, pseudopilin PulG	149
2918742857	146	96.79	9	145	6	156	5.2e-31	102.8	COG2165	Type II secretory pathway, pseudopilin PulG	149
2918742859	529	97.69	9	348	8	345	1.9e-130	429.4	COG1171	Threonine dehydratase	347
2918742860	376	66.87	66	369	93	316	1.4e-08	29.3	COG0582	Integrase	309
2918742861	362	87.78	7	362	45	360	6.0e-41	135.2	COG3203	Outer membrane protein (porin)	354
2918742863	149	97.08	1	148	2	134	3.9e-36	118.5	COG1765	Uncharacterized OsmC-related protein	137
2918742864	209	98.07	5	209	5	207	8.5e-63	206.2	COG2941	Demethoxyubiquinone hydroxylase, CLK1/Coq7/Cat5 family	204
2918742865	414	100	1	414	1	360	9.0e-50	164.2	COG3203	Outer membrane protein (porin)	354
2918742866	326	99.69	1	322	1	317	1.1e-109	361.3	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2918742867	424	96.95	16	406	7	387	1.7e-123	406.9	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
2918742868	528	95.85	2	527	19	572	5.3e-100	330.4	COG0747	ABC-type transport system, periplasmic component	556
2918742869	303	91.28	2	303	25	296	1.2e-100	330.8	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2918742870	356	99.38	3	318	1	323	2.4e-125	412.3	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
2918742871	332	96.56	3	321	3	311	5.7e-116	381.8	COG4608	ABC-type oligopeptide transport system, ATPase component	309
2918742872	308	98.51	44	308	4	268	4.0e-81	266.9	COG3384	Aromatic ring-opening dioxygenase, catalytic subunit, LigB family	268
2918742873	489	98.56	1	488	7	485	0.0e+00	579.9	COG0364	Glucose-6-phosphate 1-dehydrogenase	483
2918742874	337	96.35	37	334	9	298	1.9e-79	261.5	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
2918742875	757	97.61	170	740	9	539	0.0e+00	467.1	COG1178	ABC-type Fe3+ transport system, permease component	540
2918742876	349	97.45	1	348	5	348	4.8e-115	379.2	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
2918742877	210	86.58	1	207	5	204	3.1e-30	100.3	COG1011	FMN phosphatase YigB, HAD superfamily	229
2918742878	226	84	61	226	23	169	6.8e-42	137.2	COG3040	Bacterial lipocalin	174
2918742879	318	99.34	4	315	2	303	3.4e-98	323.6	COG0176	Transaldolase	239
2918742880	520	96.03	45	508	5	439	0.0e+00	546.6	COG0166	Glucose-6-phosphate isomerase	446
2918742881	109	92.36	3	109	4	136	1.9e-25	80.4	COG3152	Uncharacterized membrane protein YhaH, DUF805 family	125
2918742882	354	98.49	12	342	2	327	4.7e-95	313.3	COG1995	4-hydroxy-L-threonine phosphate dehydrogenase PdxA	332
2918742883	325	98.12	4	324	6	318	4.5e-89	293.2	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918742884	311	96.01	16	311	4	292	9.3e-56	184.4	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918742885	436	97.29	1	433	12	442	2.4e-68	226.1	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
2918742886	285	94.63	1	285	11	292	1.5e-76	252.2	COG1175	ABC-type sugar transport system, permease component	295
2918742887	274	96.11	1	274	12	283	4.4e-68	224.4	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
2918742888	345	99.71	1	339	1	349	0.0e+00	447.8	COG3839	ABC-type sugar transport system, ATPase component	338
2918742889	486	93.04	9	480	18	458	1.2e-124	411	COG0246	Mannitol-1-phosphate/altronate dehydrogenases	473
2918742890	262	99.25	3	260	2	267	8.8e-71	233.1	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918742891	223	79.93	3	215	9	251	1.8e-42	134.3	COG0176	Transaldolase	239
2918742892	322	97.47	2	313	2	309	6.4e-61	200.6	COG0524	Sugar or nucleoside kinase, ribokinase family	311
2918742893	312	77.27	106	310	24	125	1.1e-27	90	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918742894	489	98.21	1	489	6	498	0.0e+00	492.2	COG1070	Sugar (pentulose or hexulose) kinase	502
2918742895	550	98.73	1	539	1	543	0.0e+00	603.4	COG0459	Chaperonin GroEL (HSP60 family)	524
2918742896	96	98.96	1	96	1	95	6.5e-40	129.9	COG0234	Co-chaperonin GroES (HSP10)	96
2918742897	249	72.35	9	205	6	196	6.7e-11	35.4	COG5266	Uncharacterized conserved protein, contains GH25 family domain	264
2918742898	677	93.71	1	675	42	786	2.2e-111	368.4	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2918742899	534	76.7	40	500	64	435	1.2e-74	246.1	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
2918742900	700	95.72	22	700	35	795	1.1e-104	346.3	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2918742901	395	87.58	1	385	7	394	4.3e-73	241	COG3182	Uncharacterized iron-regulated membrane protein	442
2918742902	60	22.07	5	60	47	95	1.3e-03	12.9	COG3201	Nicotinamide riboside transporter PnuC	222
2918742903	709	96.6	1	704	25	792	2.4e-80	265.8	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2918742904	434	97.94	31	418	4	383	4.4e-75	247.9	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918742905	243	99.17	1	240	2	241	1.2e-109	359.7	COG1126	ABC-type polar amino acid transport system, ATPase component	240
2918742906	216	92.11	1	216	14	223	6.9e-69	226.6	COG0765	ABC-type amino acid transport system, permease component	222
2918742907	253	92.23	1	253	12	272	3.8e-54	178.6	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918742908	215	53.08	32	161	2	70	1.8e-15	52.4	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918742909	393	99.23	1	393	2	387	0.0e+00	618.6	COG0192	S-adenosylmethionine synthetase	388
2918742910	298	90.58	1	291	22	300	2.5e-58	192	COG1560	Lauroyl/myristoyl acyltransferase	308
2918742911	294	93.83	2	294	19	307	2.3e-75	248.1	COG1560	Lauroyl/myristoyl acyltransferase	308
2918742912	303	97.29	7	303	8	294	1.8e-36	120.8	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918742913	229	95.5	15	213	5	195	2.0e-55	181.7	COG0218	GTP-binding protein EngB required for normal cell division	200
2918742914	222	53.33	146	222	43	114	2.4e-51	60.8	COG2863	Cytochrome c553	121
2918742914	222	88.89	3	145	15	134	2.4e-51	107.7	COG2863	Cytochrome c553	121
2918742915	702	98.46	7	669	1	513	2.1e-103	340.9	COG1333	Cytochrome c biogenesis protein ResB	478
2918742916	438	99.29	101	437	2	281	4.0e-68	224.7	COG0755	ABC-type transport system involved in cytochrome c biogenesis, permease component	281
2918742917	336	96.89	27	310	4	283	3.2e-90	296.6	COG2041	Periplasmic DMSO/TMAO reductase YedYZ, molybdopterin-dependent catalytic subunit	271
2918742918	222	89.15	2	208	15	203	7.0e-60	196.8	COG2717	Periplasmic DMSO/TMAO reductase YedYZ, heme-binding membrane subunit	209
2918742919	427	98.99	12	402	5	395	5.9e-130	428	COG0019	Diaminopimelate decarboxylase	394
2918742920	73	44.83	1	72	10	35	1.4e-06	22.8	COG5567	Predicted small periplasmic lipoprotein YifL (function unknown0	58
2918742921	110	99.06	1	108	1	105	1.8e-31	102.9	COG1965	Iron-binding protein CyaY, frataxin homolog	106
2918742922	774	91.32	1	728	8	733	0.0e+00	880.3	COG5009	Membrane carboxypeptidase/penicillin-binding protein	797
2918742923	345	96.33	1	344	13	353	1.4e-100	331.3	COG4972	Tfp pilus assembly protein, ATPase PilM	354
2918742924	206	89.42	1	203	7	192	7.4e-40	131.3	COG3166	Tfp pilus assembly protein PilN	206
2918742925	227	92.42	21	227	9	203	1.9e-66	218.2	COG3167	Tfp pilus assembly protein PilO	211
2918742926	180	97.65	4	179	4	169	3.1e-48	158.5	COG3168	Tfp pilus assembly protein PilP	170
2918742927	690	92.73	2	685	52	714	0.0e+00	524.4	COG4796	Type II secretory pathway, component HofQ	709
2918742928	182	94.19	1	169	5	166	2.2e-51	168.8	COG0703	Shikimate kinase	172
2918742929	370	99.17	10	369	3	359	0.0e+00	442.8	COG0337	3-dehydroquinate synthetase	360
2918742930	376	97.39	1	373	11	420	5.3e-111	366.5	COG0232	dGTP triphosphohydrolase	412
2918742931	418	49.61	216	417	5	194	4.5e-12	9.7	COG0477	MFS family permease	338
2918742931	418	82.77	8	278	5	321	4.5e-12	33.6	COG0477	MFS family permease	338
2918742932	191	88.78	3	187	13	186	2.6e-74	243.4	COG3310	Uncharacterized protein	196
2918742934	231	97.06	1	140	1	132	4.4e-20	66.6	COG1943	REP element-mobilizing transposase RayT	136
2918742935	1582	6.13	642	710	355	384	0.0e+00	4.6	COG0069	Glutamate synthase domain 2	485
2918742935	1582	97.04	1243	1562	2	296	3.3e-106	349.4	COG0070	Glutamate synthase domain 3	301
2918742935	1582	99.39	718	1237	2	487	0.0e+00	711.9	COG0069	Glutamate synthase domain 2	485
2918742935	1582	99.73	13	400	2	372	0.0e+00	480.2	COG0067	Glutamate synthase domain 1	371
2918742936	492	99.13	22	490	1	454	0.0e+00	566.6	COG0493	NADPH-dependent glutamate synthase beta chain or related oxidoreductase	457
2918742937	275	96.2	3	265	6	258	4.7e-104	341.8	COG1127	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, ATPase component MlaF	263
2918742938	260	93.63	5	260	15	264	4.7e-87	286.1	COG0767	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, permease component MlaE	267
2918742939	163	44.59	1	163	1	165	2.4e-46	153.2	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2918742940	201	76.1	1	200	42	232	9.4e-69	225.9	COG2853	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, lipoprotein component MlaA	250
2918742941	219	96.04	12	212	8	201	4.5e-53	174.5	COG2854	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic MlaC component	202
2918742942	90	84.85	1	89	13	96	6.6e-14	46.7	COG3113	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, MlaB component, contains STAS domain	99
2918742943	315	98.69	1	306	3	304	6.0e-87	286.5	COG1131	ABC-type multidrug transport system, ATPase component	293
2918742944	254	74.4	8	253	74	291	3.9e-18	60.2	COG0842	ABC-type multidrug transport system, permease component	286
2918742945	80	96.25	1	80	1	77	1.5e-32	106.4	COG5007	Acid stress-induced BolA-like protein IbaG/YrbA, predicted regulator of iron metabolism	80
2918742946	429	99.52	1	427	1	419	0.0e+00	602.4	COG0766	UDP-N-acetylglucosamine enolpyruvyl transferase	421
2918742947	213	73.38	1	213	2	216	1.8e-74	245.3	COG0040	ATP phosphoribosyltransferase	290
2918742948	440	95.8	8	440	17	427	0.0e+00	568.8	COG0141	Histidinol dehydrogenase	425
2918742950	363	96.68	9	363	7	355	4.7e-98	322.8	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
2918742951	202	99.49	6	202	2	195	8.3e-86	281.2	COG0131	Imidazoleglycerol phosphate dehydratase HisB	195
2918742952	218	99.02	5	218	2	203	3.9e-74	243.5	COG0118	Imidazoleglycerol phosphate synthase glutamine amidotransferase subunit HisH	204
2918742953	247	97.93	1	243	2	237	2.3e-92	303.1	COG0106	Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase	241
2918742954	390	98.93	1	390	3	372	2.0e-109	360.3	COG4637	Predicted ATPase	373
2918742955	306	95.05	1	284	5	273	3.8e-55	181.7	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918742956	435	97.85	1	427	4	412	0.0e+00	432.7	COG1301	Na+/H+-dicarboxylate symporter	415
2918742957	278	85.22	3	277	34	281	3.4e-60	198.1	COG0676	D-hexose-6-phosphate mutarotase	287
2918742958	259	99.61	1	259	1	256	2.6e-114	375.4	COG0107	Imidazole glycerol phosphate synthase subunit HisF	256
2918742959	129	92.86	1	110	7	110	1.3e-42	138.8	COG0139	Phosphoribosyl-AMP cyclohydrolase	111
2918742960	126	97.92	11	117	1	94	9.4e-31	100.5	COG0140	Phosphoribosyl-ATP pyrophosphohydrolase	92
2918742961	129	84.8	1	128	13	118	2.5e-16	53.9	COG3671	Uncharacterized membrane protein	125
2918742962	119	73.05	5	116	2	104	1.8e-32	106.6	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
2918742963	82	65.96	1	82	1	62	5.1e-21	69.7	COG1826	Sec-independent protein translocase protein TatA	94
2918742964	152	88.3	1	94	3	85	3.2e-17	57.2	COG1826	Sec-independent protein translocase protein TatA	94
2918742965	271	96.91	9	267	6	256	9.5e-73	239.3	COG0805	Sec-independent protein secretion pathway component TatC	255
2918742966	386	96.99	6	377	5	358	1.7e-119	393.7	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
2918742967	447	48.83	248	444	8	194	2.3e-30	13	COG0477	MFS family permease	338
2918742967	447	74.93	24	291	4	290	2.3e-30	94.3	COG0477	MFS family permease	338
2918742968	257	98.82	3	257	3	253	5.4e-60	197.3	COG0327	Putative GTP cyclohydrolase 1 type 2, NIF3 family	250
2918742969	352	97.28	6	352	5	326	2.3e-103	340.7	COG1995	4-hydroxy-L-threonine phosphate dehydrogenase PdxA	332
2918742970	143	99.24	1	143	1	130	5.1e-50	163.9	COG1970	Large-conductance mechanosensitive channel	130
2918742971	230	66.38	2	168	59	212	2.0e-07	23.7	COG0671	Membrane-associated phospholipid phosphatase	232
2918742972	369	19.68	252	337	134	182	1.1e-50	15.3	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
2918742972	369	92.77	32	285	17	247	1.1e-50	158.3	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
2918742973	151	98.65	1	141	2	147	1.1e-40	133.7	COG0394	Protein-tyrosine-phosphatase	139
2918742974	750	82.87	493	747	23	259	4.9e-44	143.9	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
2918742974	750	98.71	3	482	5	463	5.0e-64	211.4	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
2918742975	237	84.89	6	237	31	221	1.6e-67	221.7	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
2918742976	382	64.25	84	370	85	332	3.6e-18	59.7	COG2327	Polysaccharide pyruvyl transferase family protein WcaK	385
2918742977	355	93.89	3	355	21	404	1.1e-46	154.8	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918742979	409	82.37	4	407	14	410	8.0e-10	31.6	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
2918742983	168	76.67	1	168	36	173	1.3e-39	130.4	COG0723	Rieske Fe-S protein	177
2918742984	478	99.01	12	472	5	405	0.0e+00	541.9	COG1290	Cytochrome b subunit of the bc complex	381
2918742985	257	88.45	3	257	33	277	1.5e-52	173.5	COG2857	Cytochrome c1	250
2918742986	185	86.51	1	184	19	204	6.2e-40	131.9	COG0625	Glutathione S-transferase	211
2918742987	197	65.81	3	121	4	105	5.0e-50	162.4	COG2969	Stringent starvation protein B	155
2918742990	262	92.48	9	244	3	211	1.7e-27	90.8	COG3619	Uncharacterized membrane protein YoaK, UPF0700 family	226
2918742991	337	98.51	89	334	2	265	9.6e-69	226.3	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918742992	573	95.04	34	550	10	488	0.0e+00	457.6	COG0608	Single-stranded DNA-specific exonuclease, DHH superfamily, may be involved in archaeal DNA replication intiation	491
2918742994	418	99.76	1	418	2	410	0.0e+00	460.6	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
2918742995	235	96.49	11	235	6	225	6.2e-83	272.3	COG4181	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component	228
2918742996	198	93.5	1	198	9	195	8.5e-59	193.4	COG0740	ATP-dependent protease ClpP, protease subunit	200
2918742997	129	87.5	3	128	17	135	1.2e-35	117	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
2918742998	524	97.4	9	524	6	568	9.0e-83	273.7	COG0747	ABC-type transport system, periplasmic component	556
2918742999	313	99.06	1	313	1	315	3.1e-114	376.3	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2918743000	277	91.61	2	276	25	297	1.2e-95	314.4	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2918743001	344	98.77	8	335	2	322	7.6e-126	413.9	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
2918743002	325	96.88	4	309	3	312	8.1e-120	394.5	COG4608	ABC-type oligopeptide transport system, ATPase component	309
2918743003	436	97.57	33	436	6	367	3.0e-89	293.8	COG3616	D-serine deaminase, pyridoxal phosphate-dependent	368
2918743004	303	98.23	1	281	4	280	1.3e-58	193	COG1737	DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains	281
2918743005	491	34.72	296	491	370	570	1.3e-107	137.8	COG3653	N-acyl-D-aspartate/D-glutamate deacylase	579
2918743005	491	53.02	2	305	8	314	1.3e-107	216.4	COG3653	N-acyl-D-aspartate/D-glutamate deacylase	579
2918743006	202	85.95	6	194	21	179	6.9e-34	111.5	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
2918743007	267	90.43	3	257	10	217	4.4e-26	86.2	COG1266	Membrane protease YdiL, CAAX protease family	226
2918743008	186	44.44	39	186	104	187	4.0e-22	73.8	COG2020	Protein-S-isoprenylcysteine O-methyltransferase Ste14	187
2918743009	252	99.25	2	250	2	267	3.2e-78	257.6	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918743010	684	93.71	519	682	10	158	4.5e-45	145.3	COG2030	Acyl dehydratase	159
2918743010	684	99.16	5	505	2	476	9.3e-78	256.3	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918743011	243	98.73	3	239	3	236	1.4e-88	290.6	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2918743012	633	96.59	19	346	8	319	2.2e-71	235.1	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918743012	633	98.82	373	623	3	253	1.1e-90	297.8	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2918743013	342	24.92	2	88	5	79	2.4e-60	49.3	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2918743013	342	79.4	83	342	52	290	2.4e-60	155.5	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2918743014	382	96.17	13	382	4	355	4.1e-59	195	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918743015	364	90.67	1	299	3	245	1.6e-64	212.4	COG1018	Ferredoxin-NADP reductase	266
2918743016	176	87.61	1	155	10	108	5.0e-24	79.1	COG2151	Metal-sulfur cluster biosynthetic enzyme	111
2918743017	259	92.45	5	259	21	265	2.5e-72	237.7	COG3396	1,2-phenylacetyl-CoA epoxidase, catalytic subunit	265
2918743018	98	88.03	2	98	7	109	1.1e-39	129.6	COG3460	1,2-phenylacetyl-CoA epoxidase, PaaB subunit	117
2918743019	336	98.49	38	304	5	265	8.4e-104	340.9	COG3396	1,2-phenylacetyl-CoA epoxidase, catalytic subunit	265
2918743020	438	96.12	5	438	15	435	0.0e+00	524.1	COG1541	Phenylacetate-coenzyme A ligase PaaK, adenylate-forming domain family	438
2918743021	147	96.45	6	143	3	138	8.5e-31	101.2	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
2918743022	267	97.74	1	264	7	265	5.5e-78	256.6	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918743023	200	95.48	1	175	7	175	3.4e-52	171	COG0663	Carbonic anhydrase or acetyltransferase, isoleucine patch superfamily	176
2918743024	213	86.6	1	199	4	184	8.2e-29	96.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918743025	345	24.09	191	291	166	231	6.0e-09	7.9	COG1240	Mg-chelatase subunit ChlD	261
2918743025	345	27.37	72	176	92	166	6.0e-09	22.7	COG1240	Mg-chelatase subunit ChlD	261
2918743026	332	60.67	16	317	164	416	5.3e-46	151.5	COG1721	Uncharacterized conserved protein, DUF58 family, contains vWF domain	416
2918743027	337	97.27	4	327	9	329	5.3e-98	322.7	COG0714	MoxR-like ATPase	329
2918743028	330	64.93	35	328	17	253	1.2e-56	186.9	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
2918743029	286	98.05	2	271	3	254	1.1e-64	212.8	COG0084	Tat protein secretion system quality control protein TatD (DNase activity)	256
2918743030	137	8.13	12	111	46	121	1.4e+00	1.5	COG5373	Uncharacterized membrane protein	931
2918743031	175	95.86	16	173	2	163	5.0e-32	106	COG3663	G:T/U-mismatch repair DNA glycosylase	169
2918743032	260	90.43	2	258	22	276	3.9e-36	119.1	COG0421	Spermidine synthase	282
2918743033	595	96.46	95	593	17	506	0.0e+00	525.5	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
2918743035	504	99.01	1	504	1	499	0.0e+00	677.4	COG3333	TctA family transporter	504
2918743036	309	98.34	9	306	2	297	4.6e-59	195.2	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918743037	324	97.81	3	323	4	315	1.2e-91	301.7	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918743038	537	96.51	7	537	19	544	0.0e+00	583.9	COG0405	Gamma-glutamyltranspeptidase	539
2918743039	316	96.01	16	315	7	295	5.4e-37	122.2	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918743040	265	98.13	4	261	4	266	4.5e-45	148.7	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918743041	302	97.01	4	302	5	296	3.6e-42	139.2	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918743042	328	99.4	3	328	2	330	1.3e-94	311.8	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2918743043	136	52.13	4	130	3	112	7.0e-15	49.8	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918743044	553	99.07	1	535	5	534	0.0e+00	549.4	COG1283	Na+/phosphate symporter	533
2918743045	285	85.57	9	282	2	339	4.3e-30	99.4	COG1409	3',5'-cyclic AMP phosphodiesterase CpdA	301
2918743046	353	97.45	4	350	5	348	1.8e-105	347.5	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
2918743047	266	95.88	1	265	6	261	1.1e-54	180	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
2918743048	275	93.07	4	275	13	267	4.5e-57	187.6	COG0555	ABC-type sulfate transport system, permease component	274
2918743049	338	98.67	45	338	2	298	8.6e-60	197.2	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
2918743050	336	98.8	1	331	2	331	8.2e-94	309.2	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
2918743051	164	93.41	2	164	5	160	1.3e-47	156	COG0597	Lipoprotein signal peptidase	167
2918743052	949	99.47	8	943	2	943	0.0e+00	1045.2	COG0060	Isoleucyl-tRNA synthetase	933
2918743053	345	95.77	1	330	14	307	2.1e-85	280.6	COG0196	FAD synthase	304
2918743055	262	96.23	3	260	11	265	7.4e-70	229.9	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918743056	450	46.44	13	277	21	157	6.4e-10	34.1	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918743057	371	98.75	1	368	1	394	2.1e-63	209.4	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918743058	393	98.75	1	393	1	394	7.1e-82	270.2	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918743059	198	93	2	197	2	187	1.0e-71	235.1	COG0299	Folate-dependent phosphoribosylglycinamide formyltransferase PurN	200
2918743060	106	39.22	1	100	14	93	4.1e-03	11.1	COG3056	Uncharacterized lipoprotein YajG	204
2918743061	82	54.84	4	82	39	106	1.0e-25	85	COG4728	Uncharacterized protein	124
2918743062	617	49.68	8	335	151	305	2.5e-14	46.3	COG0501	Zn-dependent protease with chaperone function	302
2918743063	423	86.31	76	423	49	357	1.4e-94	311.9	COG0144	16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family	355
2918743064	404	85.52	6	270	41	288	3.7e-88	290	COG1398	Fatty-acid desaturase	289
2918743065	57	94.12	5	55	4	51	1.1e-24	81.1	COG0267	Ribosomal protein L33	50
2918743066	77	98.7	1	76	1	76	6.7e-37	120.2	COG0227	Ribosomal protein L28	77
2918743067	319	98.7	4	317	2	304	2.9e-122	401.9	COG0492	Thioredoxin reductase	305
2918743068	224	98.62	9	219	2	216	3.0e-42	139.2	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2918743069	799	17.27	40	244	34	194	0.0e+00	7.1	COG1674	DNA segregation ATPase FtsK/SpoIIIE and related proteins	858
2918743069	799	56.97	217	799	398	928	0.0e+00	797.5	COG1674	DNA segregation ATPase FtsK/SpoIIIE and related proteins	858
2918743070	210	93.9	3	210	13	212	6.6e-40	131.4	COG2834	Outer membrane lipoprotein-sorting protein	211
2918743071	430	97.03	1	430	11	434	0.0e+00	582.3	COG2256	Replication-associated recombination protein RarA (DNA-dependent ATPase)	436
2918743072	309	98.34	1	308	2	297	1.2e-88	292.1	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2918743073	398	97.21	1	355	6	319	5.0e-93	306.3	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918743074	257	99.21	2	254	3	254	2.5e-103	339.4	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2918743075	266	99.16	31	266	2	236	1.8e-94	309.9	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2918743076	324	97.81	1	322	5	316	1.8e-80	264.9	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918743077	354	84.47	5	103	13	99	1.6e-13	44.3	COG0633	Ferredoxin	102
2918743077	354	95.33	101	347	8	252	1.1e-58	192.8	COG0543	NAD(P)H-flavin reductase	252
2918743078	312	92.52	16	308	4	300	1.8e-33	110.8	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2918743081	300	98.68	2	296	4	301	1.9e-108	356.7	COG0031	Cysteine synthase	300
2918743082	192	47.89	1	159	116	251	6.3e-25	82.9	COG2816	NADH pyrophosphatase NudC, Nudix superfamily	279
2918743083	75	92.5	1	75	5	78	1.6e-24	80.3	COG0425	TusA-related sulfurtransferase	78
2918743084	296	97.93	5	296	3	286	7.9e-120	393.9	COG1210	UTP-glucose-1-phosphate uridylyltransferase	291
2918743085	959	99.66	16	959	2	881	0.0e+00	1205.5	COG0525	Valyl-tRNA synthetase	877
2918743086	260	99.21	1	260	1	251	3.1e-85	280.4	COG3022	Cytoplasmic iron level regulating protein YaaA, DUF328/UPF0246 family	253
2918743088	299	96.95	2	293	7	292	7.4e-40	131.9	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918743089	292	81.75	9	134	10	121	1.8e-50	164.6	COG2904	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF, N-terminal domain	137
2918743090	301	97.01	1	250	4	263	8.5e-54	177.4	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918743091	296	97.01	5	296	1	292	1.3e-60	200.3	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918743092	295	96.35	3	294	2	291	3.3e-59	195.7	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918743093	384	90.88	3	376	30	368	6.5e-89	292.7	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
2918743094	335	98.43	13	332	4	317	6.0e-71	233.7	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918743095	235	95.8	2	235	8	235	1.0e-38	127.9	COG3473	Maleate cis-trans isomerase	238
2918743096	453	96.27	3	449	6	444	1.1e-102	338.4	COG2079	2-methylcitrate dehydratase PrpD	453
2918743097	387	96.99	3	387	11	397	6.6e-106	349.2	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918743098	262	50.76	25	255	176	376	4.1e-32	105.9	COG0372	Citrate synthase	390
2918743099	775	91.23	2	370	21	384	1.1e-118	158.7	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918743099	775	97.24	384	775	9	396	1.1e-118	238.5	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918743100	328	94.04	7	326	6	305	1.5e-84	278.4	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918743101	503	97.36	1	501	7	559	2.9e-98	324.1	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2918743104	393	94.66	2	362	17	353	5.7e-101	332.5	COG3569	DNA topoisomerase IB	354
2918743105	354	92.55	16	354	25	347	1.1e-62	205.1	COG5042	Purine nucleoside permease	349
2918743107	416	10.16	12	52	1	38	2.0e-82	34.3	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
2918743107	416	90.91	58	394	27	366	2.0e-82	235.9	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
2918743110	187	95.79	1	186	7	188	1.2e-40	133.9	COG3554	Uncharacterized protein	190
2918743111	334	96.24	12	328	6	312	6.7e-75	246.5	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918743112	306	99.34	1	306	1	299	8.7e-60	197.6	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918743113	912	64.41	182	526	87	276	5.3e-05	14.5	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918743114	450	69.16	105	406	91	303	8.6e-06	15.9	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
2918743115	324	97.81	1	323	7	318	6.4e-84	276.4	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918743116	411	48.83	212	408	8	194	1.2e-39	31.3	COG0477	MFS family permease	338
2918743116	411	62.92	1	254	8	248	1.2e-39	106.6	COG0477	MFS family permease	338
2918743117	385	96.4	10	384	2	349	4.0e-129	424.9	COG1304	FMN-dependent dehydrogenase, includes L-lactate dehydrogenase and type II isopentenyl diphosphate isomerase	360
2918743118	294	97.34	7	294	4	296	4.5e-52	172.3	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918743119	196	90.91	1	196	14	203	2.2e-23	78.8	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918743120	140	88.96	1	140	2	138	1.4e-73	240.6	COG3558	Uncharacterized conserved protein, nuclear transport factor 2 (NTF2) superfamily	154
2918743121	395	61.07	74	391	147	375	1.7e-54	180	COG4585	Signal transduction histidine kinase	365
2918743122	222	98.58	4	219	1	208	1.0e-53	176.7	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918743123	451	96.12	62	391	11	332	6.1e-73	240.2	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918743124	289	10.08	1	36	5	30	1.4e-67	4.7	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2918743124	289	84.88	55	289	34	252	1.4e-67	221.8	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2918743125	275	96.81	12	274	3	245	4.9e-83	272.9	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2918743126	147	97.35	1	147	5	151	3.3e-58	190.6	COG1513	Cyanate lyase	151
2918743127	250	92.28	1	231	1	227	1.2e-65	216.1	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
2918743128	483	98.25	5	475	5	452	3.7e-121	399.5	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
2918743129	377	85.35	3	372	52	389	2.8e-52	172.5	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
2918743130	196	98.37	3	193	2	182	9.3e-31	101.6	COG0431	NAD(P)H-dependent FMN reductase	184
2918743133	528	96.37	1	527	11	567	6.0e-74	244.5	COG0747	ABC-type transport system, periplasmic component	556
2918743134	313	99.37	1	313	1	316	2.8e-113	373.2	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2918743135	315	91.61	12	313	24	296	6.6e-91	298.9	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2918743136	538	98.91	1	533	3	548	0.0e+00	643.5	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
2918743137	500	96.97	1	500	1	480	0.0e+00	473.5	COG5476	Microcystin degradation protein MlrC, contains DUF1485 domain	488
2918743138	394	97.96	5	394	6	390	1.4e-130	430.4	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
2918743139	426	96.46	26	422	11	392	3.7e-126	415.6	COG2807	Cyanate permease	395
2918743140	229	94.61	1	227	6	233	3.1e-57	188.3	COG2186	DNA-binding transcriptional regulator, FadR family	241
2918743141	751	79.16	9	652	10	590	1.3e-127	421.1	COG4953	Membrane carboxypeptidase/penicillin-binding protein PbpC	733
2918743143	208	99.52	1	206	1	207	1.3e-54	179.2	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
2918743144	89	98.86	1	88	1	87	1.1e-35	116.6	COG5552	Uncharacterized protein	88
2918743145	164	86.63	8	164	19	180	3.2e-19	64.2	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
2918743146	141	57.41	3	129	62	154	2.5e-08	29.3	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2918743147	357	71.64	8	303	13	252	6.6e-40	131.7	COG2603	tRNA 2-selenouridine synthase SelU, contains rhodanese domain	334
2918743149	149	89.74	4	145	4	143	1.0e-23	77.4	COG0328	Ribonuclease HI	154
2918743151	173	96.15	1	173	2	176	8.9e-61	199.5	COG2110	O-acetyl-ADP-ribose deacetylase (regulator of RNase III), contains Macro domain	179
2918743152	2011	10.47	1778	2010	1461	1631	6.1e-78	50.2	COG2373	Uncharacterized conserved protein YfaS, alpha-2-macroglobulin family	1621
2918743152	2011	22.17	1144	1528	823	1184	6.1e-78	119.2	COG2373	Uncharacterized conserved protein YfaS, alpha-2-macroglobulin family	1621
2918743152	2011	32.88	501	1136	291	827	6.1e-78	92.9	COG2373	Uncharacterized conserved protein YfaS, alpha-2-macroglobulin family	1621
2918743153	380	77.32	1	362	21	337	3.1e-42	139.3	COG4645	Uncharacterized protein	410
2918743154	264	75.11	84	247	41	206	1.5e-12	41.6	COG2755	Lysophospholipase L1 or related esterase	216
2918743157	492	12.72	3	35	3	31	1.5e-35	3.5	COG0705	Membrane associated serine protease, rhomboid family	228
2918743157	492	65.35	112	302	59	207	1.5e-35	116.2	COG0705	Membrane associated serine protease, rhomboid family	228
2918743158	465	99.35	8	465	2	457	0.0e+00	655.2	COG0165	Argininosuccinate lyase	459
2918743159	332	35.91	95	332	351	550	4.2e-46	151.9	COG3275	Sensor histidine kinase, LytS/YehU family	557
2918743160	243	98.79	2	242	2	246	2.8e-55	182.4	COG3279	DNA-binding response regulator, LytR/AlgR family	244
2918743161	417	95	52	417	12	353	1.2e-72	239.4	COG0628	Predicted PurR-regulated permease PerM	355
2918743162	417	45.95	220	415	20	195	2.3e-23	24	COG0477	MFS family permease	338
2918743162	417	76.5	8	266	8	300	2.3e-23	54.4	COG0477	MFS family permease	338
2918743163	174	97.04	10	174	2	165	4.0e-54	177.6	COG1247	L-amino acid N-acyltransferase YncA	169
2918743164	307	98.67	5	301	1	297	3.4e-62	205.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918743165	412	97.47	15	405	5	389	2.0e-99	327.4	COG2814	Predicted arabinose efflux permease, MFS family	394
2918743167	2729	10.7	1461	1608	323	435	0.0e+00	27.6	COG3459	Cellobiose phosphorylase	1056
2918743167	2729	96.21	1651	2708	3	1018	0.0e+00	793	COG3459	Cellobiose phosphorylase	1056
2918743169	947	99.67	12	947	4	913	0.0e+00	1097.6	COG2352	Phosphoenolpyruvate carboxylase	910
2918743170	301	96.42	1	301	3	298	4.5e-113	372	COG0181	Porphobilinogen deaminase	307
2918743171	257	96	3	257	2	241	1.1e-33	111	COG1587	Uroporphyrinogen-III synthase	248
2918743172	363	83.84	2	362	26	357	2.3e-47	156.4	COG2959	Uncharacterized conserved protein HemX (no evidence of involvement in heme biosynthesis)	391
2918743173	427	95.25	1	426	3	383	2.5e-36	119	COG3071	Uncharacterized conserved protein HemY, contains two TPR repeats	400
2918743174	1073	99.59	1	490	1	487	0.0e+00	657.4	COG1530	Ribonuclease G or E	487
2918743175	370	98.63	38	346	4	291	3.1e-75	247.7	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
2918743176	223	96.85	9	222	5	219	1.5e-50	166.8	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
2918743177	123	96.26	2	115	4	106	1.2e-17	58.3	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
2918743178	317	91.25	9	316	12	303	1.0e-74	246.4	COG0616	Periplasmic serine protease, ClpP class	317
2918743179	384	37.72	13	184	234	382	6.6e-19	37.7	COG2814	Predicted arabinose efflux permease, MFS family	394
2918743179	384	55.95	165	384	170	390	6.6e-19	32.9	COG2814	Predicted arabinose efflux permease, MFS family	394
2918743180	254	79.41	1	254	3	218	2.3e-45	149.4	COG0313	16S rRNA C1402 (ribose-2'-O) methylase RsmI	275
2918743181	193	98.45	1	193	2	192	1.0e-57	189.2	COG0424	Predicted house-cleaning NTP pyrophosphatase, Maf/HAM1 superfamily	193
2918743182	185	94.97	1	179	7	176	1.1e-24	82.1	COG1399	Uncharacterized metal-binding protein YceD, DUF177 family	176
2918743183	60	98.25	1	56	1	56	2.2e-23	76.9	COG0333	Ribosomal protein L32	57
2918743184	365	98.23	15	348	2	334	1.6e-123	406.5	COG0416	Fatty acid/phospholipid biosynthesis enzyme	338
2918743185	325	98.77	2	325	3	324	0.0e+00	430.3	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
2918743186	317	96.76	1	316	1	329	3.4e-75	247.8	COG0331	Malonyl CoA-acyl carrier protein transacylase	310
2918743187	247	99.25	4	246	2	267	1.6e-77	255.3	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918743188	79	96.3	1	78	3	80	2.5e-31	102.3	COG0236	Acyl carrier protein	80
2918743189	414	99.52	2	414	2	413	0.0e+00	523	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
2918743191	211	97.31	15	208	4	184	2.8e-53	174.9	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918743192	214	58.22	1	201	6	129	2.7e-15	51.5	COG3073	Negative regulator of sigma E activity	213
2918743193	352	92.5	16	351	19	314	8.2e-61	200.3	COG3026	Negative regulator of sigma E activity	320
2918743194	493	14.52	401	487	294	346	1.1e-124	28.3	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
2918743194	493	89.04	10	383	36	360	1.1e-124	385.1	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
2918743195	603	98.84	1	603	6	601	0.0e+00	1003	COG0481	Translation elongation factor EF-4, membrane-bound GTPase	603
2918743196	321	86.93	92	311	3	155	5.1e-33	108	COG0681	Signal peptidase I	166
2918743198	228	94.49	3	227	9	231	3.0e-68	224	COG0571	dsRNA-specific ribonuclease	235
2918743199	321	97.99	22	321	4	295	2.8e-105	346.2	COG1159	GTPase Era, involved in 16S rRNA processing	298
2918743200	244	92.86	1	244	12	245	1.5e-38	127.2	COG1381	Recombinational DNA repair protein (RecF pathway)	251
2918743201	254	98.77	10	254	2	241	7.9e-73	239.3	COG0854	Pyridoxine 5'-phosphate synthase PdxJ	243
2918743202	130	98.43	1	130	1	125	2.3e-35	116.2	COG0736	Phosphopantetheinyl transferase (holo-ACP synthase)	127
2918743203	367	65.95	6	332	8	282	1.0e-81	269.7	COG1472	Periplasmic beta-glucosidase and related glycosidases	397
2918743204	176	71.81	1	167	58	220	1.6e-30	101.2	COG1451	Predicted metal-dependent hydrolase	223
2918743205	420	16.01	294	415	257	353	3.7e-58	28	COG0443	Molecular chaperone DnaK (HSP70)	579
2918743205	420	47.36	3	291	7	293	3.7e-58	162	COG0443	Molecular chaperone DnaK (HSP70)	579
2918743206	520	97.84	12	520	11	508	0.0e+00	691.8	COG1190	Lysyl-tRNA synthetase (class II)	502
2918743207	215	90.05	1	213	6	204	1.3e-42	140.8	COG2802	Uncharacterized protein, similar to the N-terminal domain of Lon protease	221
2918743208	198	58.33	13	101	36	91	1.1e-24	26	COG0762	Uncharacterized conserved protein YggT, Ycf19 family	96
2918743208	198	87.5	104	195	9	92	1.1e-24	61.4	COG0762	Uncharacterized conserved protein YggT, Ycf19 family	96
2918743209	290	97.28	1	290	1	286	1.4e-124	409.7	COG0777	Acetyl-CoA carboxylase beta subunit	294
2918743210	309	98.49	29	297	3	263	9.9e-92	301.2	COG0159	Tryptophan synthase alpha chain	265
2918743211	425	98.23	6	411	2	390	0.0e+00	649.4	COG0133	Tryptophan synthase beta chain	396
2918743212	231	99.04	6	225	2	208	6.0e-55	180.9	COG0135	Phosphoribosylanthranilate isomerase	208
2918743213	270	93.26	1	261	3	251	2.4e-78	257.7	COG0101	tRNA U38,U39,U40 pseudouridine synthase TruA	266
2918743214	913	98.01	2	913	17	853	3.1e-80	252	COG3170	Tfp pilus assembly protein FimV	755
2918743215	380	98.81	7	378	4	335	1.5e-99	328.1	COG0136	Aspartate-semialdehyde dehydrogenase	334
2918743216	362	98.56	1	358	4	346	0.0e+00	451.3	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
2918743217	216	98.45	1	212	1	190	3.4e-82	269.5	COG0066	3-isopropylmalate dehydratase small subunit	191
2918743218	473	99.53	1	473	2	428	0.0e+00	638.1	COG0065	Homoaconitase/3-isopropylmalate dehydratase large subunit	423
2918743219	317	97.34	12	311	1	293	8.3e-57	187.7	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918743220	46	97.73	1	43	2	44	5.4e-15	49.6	COG5510	Predicted small secreted protein	44
2918743221	436	99.75	30	436	2	396	0.0e+00	517.8	COG0372	Citrate synthase	390
2918743222	107	84.04	3	95	11	89	1.6e-20	67.3	COG2938	Succinate dehydrogenase flavin-adding protein, antitoxin component of the CptAB toxin-antitoxin module	94
2918743223	233	98.3	1	233	1	231	4.5e-93	305.3	COG0479	Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit	234
2918743224	602	99.47	6	588	3	565	0.0e+00	736.5	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
2918743225	121	94.02	6	121	7	116	6.0e-30	98.1	COG2142	Succinate dehydrogenase, hydrophobic anchor subunit	117
2918743226	148	92.48	15	148	8	130	1.7e-22	74.5	COG2009	Succinate dehydrogenase/fumarate reductase, cytochrome b subunit	132
2918743227	252	96.65	8	251	6	236	1.2e-61	202.8	COG2188	DNA-binding transcriptional regulator, GntR family	236
2918743228	328	98.41	6	328	1	310	6.9e-82	269.7	COG0039	Malate/lactate dehydrogenase	313
2918743229	259	99.22	2	259	2	256	3.0e-110	362.5	COG4106	Trans-aconitate methyltransferase	257
2918743230	332	93.33	32	319	17	282	2.5e-50	165.6	COG2301	Citrate lyase beta subunit	283
2918743231	179	89.31	1	151	7	123	4.8e-05	15.4	COG5455	Periplasmic regulator RcnB of Ni and Co efflux	129
2918743232	862	99.53	1	861	1	848	0.0e+00	1501.5	COG1049	Aconitase B	852
2918743233	752	18.55	416	550	325	398	3.1e-82	9.2	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918743233	752	86.22	47	417	17	360	3.1e-82	254.8	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918743234	281	44.62	20	138	3	60	2.7e-11	38.3	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918743236	964	98.97	9	963	9	869	0.0e+00	1182.9	COG1048	Aconitase A	861
2918743237	150	92.44	1	149	3	161	8.3e-28	91.4	COG0622	Predicted phosphodiesterase	172
2918743238	102	94.67	15	94	3	73	1.4e-17	58	COG1918	Fe2+ transport system protein FeoA	75
2918743239	631	24.16	16	198	4	161	0.0e+00	200.1	COG0370	Fe2+ transport system protein B	653
2918743239	631	63.61	192	630	237	652	0.0e+00	465.2	COG0370	Fe2+ transport system protein B	653
2918743241	394	96.69	1	393	2	381	5.5e-58	191.8	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2918743243	286	99.62	25	286	2	262	2.2e-125	412.1	COG3483	Tryptophan 2,3-dioxygenase (vermilion)	262
2918743244	428	98.77	1	418	5	406	0.0e+00	534.3	COG3844	Kynureninase	407
2918743245	217	97.26	6	216	5	217	2.6e-44	145.6	COG1878	Kynurenine formamidase	218
2918743246	102	54.93	1	97	12	89	1.0e-09	33.2	COG0727	Fe-S-cluster containining protein	132
2918743247	311	98.39	5	308	5	310	3.7e-116	382.4	COG0078	Ornithine carbamoyltransferase	310
2918743248	402	96.79	1	399	9	400	0.0e+00	474.4	COG4992	Acetylornithine/succinyldiaminopimelate/putrescine aminotransferase	404
2918743250	104	94.32	1	97	5	87	5.0e-28	92.1	COG0268	Ribosomal protein S20	88
2918743251	517	98.84	1	517	6	517	0.0e+00	510.7	COG0728	Peptidoglycan biosynthesis protein MviN/MurJ, putative lipid II flippase	518
2918743252	283	94.07	9	283	12	265	6.0e-68	223.6	COG2912	Regulator of sirC expression, contains transglutaminase-like and TPR domains	269
2918743253	142	21.17	21	64	2	30	2.6e-08	9.2	COG2764	Uncharacterized conserved protein PhnB, glyoxalase superfamily	136
2918743253	142	32.12	86	137	83	126	2.6e-08	17.7	COG2764	Uncharacterized conserved protein PhnB, glyoxalase superfamily	136
2918743254	140	99.19	1	120	1	122	3.7e-44	144.2	COG3795	Uncharacterized conserved protein	123
2918743255	138	99.19	1	124	1	122	2.3e-37	122.5	COG3795	Uncharacterized conserved protein	123
2918743256	324	84.38	6	324	51	331	2.5e-76	251.6	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
2918743257	431	98.55	8	430	5	413	0.0e+00	552.3	COG4941	Predicted RNA polymerase sigma factor, contains C-terminal TPR domain	415
2918743258	330	93.23	2	326	4	306	1.1e-62	206.3	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
2918743259	207	56.92	1	205	8	192	4.5e-44	145.4	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
2918743260	194	94.66	1	178	4	198	2.0e-23	77.3	COG1335	Nicotinamidase-related amidase	205
2918743261	354	91.11	9	352	15	342	6.3e-16	50.7	COG0628	Predicted PurR-regulated permease PerM	355
2918743262	346	96.81	6	345	4	337	0.0e+00	457	COG0150	Phosphoribosylaminoimidazole (AIR) synthetase	345
2918743263	228	15.94	1	83	96	164	2.0e-34	28.5	COG0593	Chromosomal replication initiation ATPase DnaA	408
2918743263	228	31.18	89	228	201	335	2.0e-34	84	COG0593	Chromosomal replication initiation ATPase DnaA	408
2918743264	543	97.11	35	471	5	407	4.6e-94	310.5	COG0617	tRNA nucleotidyltransferase/poly(A) polymerase	412
2918743265	211	84.47	59	210	3	138	1.2e-44	146.3	COG0801	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase	160
2918743266	214	98.16	1	213	5	217	7.5e-50	164	COG1392	Uncharacterized conserved protein YkaA, distantly related to PhoU, UPF0111/DUF47 family	217
2918743267	336	99.44	7	336	3	354	7.5e-93	305.6	COG0306	Phosphate/sulfate permease	326
2918743268	148	47.42	1	93	8	53	8.6e-03	9	COG2314	Uncharacterized membrane protein YozV, TM2 domain	95
2918743269	174	98.22	2	170	2	167	1.9e-54	178.7	COG1247	L-amino acid N-acyltransferase YncA	169
2918743270	87	92.22	1	87	1	83	6.9e-32	104	COG0228	Ribosomal protein S16	87
2918743271	184	95.4	6	184	6	171	6.9e-46	150.5	COG0806	Ribosomal 30S subunit maturation factor RimM, required for 16S rRNA processing	174
2918743272	248	95.49	1	247	1	233	5.9e-93	304.9	COG0336	tRNA G37 N-methylase TrmD	240
2918743273	127	94.26	1	116	7	121	9.8e-49	159	COG0335	Ribosomal protein L19	115
2918743274	239	75.58	54	216	15	144	5.5e-21	69.6	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2918743275	333	96.56	1	333	10	318	5.0e-47	152.5	COG1270	Cobalamin biosynthesis protein CobD/CbiB	320
2918743276	362	98.61	8	362	2	357	4.0e-102	336.3	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
2918743277	318	93.38	15	318	15	296	3.9e-73	240.7	COG1162	Putative ribosome biogenesis GTPase RsgA	301
2918743278	116	93.07	13	114	4	97	5.9e-30	97.8	COG2154	Pterin-4a-carbinolamine dehydratase	101
2918743279	421	88.46	47	421	30	305	5.4e-43	141.7	COG0501	Zn-dependent protease with chaperone function	302
2918743280	198	97.83	16	198	2	181	6.7e-81	264.7	COG1949	Oligoribonuclease (3'-5' exoribonuclease)	184
2918743281	637	74.62	40	513	28	415	1.2e-130	430.1	COG0513	Superfamily II DNA and RNA helicase	513
2918743283	330	86.32	1	325	5	288	7.4e-81	266.4	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
2918743284	267	97.29	4	265	7	293	2.4e-28	94.3	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918743285	292	35.65	170	292	214	331	7.7e-55	50.2	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2918743285	292	53.17	1	177	1	176	7.7e-55	129.3	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2918743286	158	93.23	18	147	5	128	2.8e-26	86.6	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918743287	730	97.05	9	708	16	640	0.0e+00	736.1	COG4231	TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit	640
2918743288	502	94.12	5	218	3	194	1.7e-27	90.6	COG1014	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, gamma subunit	203
2918743289	330	97.39	3	269	5	265	4.2e-53	174.9	COG1018	Ferredoxin-NADP reductase	266
2918743290	437	89.1	15	421	3	337	3.4e-54	179	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
2918743291	162	89.63	4	154	6	152	3.0e-21	70.6	COG5517	3-phenylpropionate/cinnamic acid dioxygenase, small subunit	164
2918743292	545	91.9	3	532	38	559	4.1e-79	260.8	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2918743293	390	88.83	12	386	29	378	7.4e-48	157.9	COG0183	Acetyl-CoA acetyltransferase	392
2918743294	417	67.38	32	139	22	116	4.0e-19	62.5	COG1545	Uncharacterized OB-fold protein, contains Zn-ribbon domain	140
2918743294	417	77.99	165	410	5	213	3.6e-28	93.3	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918743295	270	98.17	23	267	3	217	1.2e-61	202.2	COG1878	Kynurenine formamidase	218
2918743296	243	99.25	1	238	1	266	1.1e-53	177.2	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918743297	388	95.63	13	388	3	352	4.6e-54	178.4	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918743298	381	97.54	12	381	2	358	4.2e-59	195	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918743299	441	88.3	16	441	4	335	3.0e-50	166	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
2918743300	155	87.2	4	147	11	153	3.5e-26	86.6	COG5517	3-phenylpropionate/cinnamic acid dioxygenase, small subunit	164
2918743301	387	92.9	9	385	8	347	2.7e-50	165.9	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918743302	351	98.67	2	347	3	299	9.9e-55	172.8	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2918743303	595	97.21	4	317	9	322	6.0e-68	223.7	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918743303	595	99.21	343	593	3	254	5.3e-93	305.3	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2918743304	243	99.16	2	237	2	236	8.3e-92	301.2	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2918743305	534	97.71	5	524	10	564	1.2e-88	292.3	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2918743306	253	98.88	6	252	3	267	1.5e-72	239	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918743307	258	98.88	4	257	2	266	2.6e-70	231.7	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918743308	175	88.72	28	166	7	124	3.7e-24	79.7	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918743309	152	93.53	11	148	5	134	2.6e-27	90	COG0824	Acyl-CoA thioesterase FadM	137
2918743314	235	97.39	3	235	4	264	3.2e-48	159.3	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918743316	194	71.43	20	193	12	131	7.0e-29	90.5	COG4960	Flp pilus assembly protein, protease CpaA	168
2918743317	280	89.49	1	263	1	247	3.2e-62	204.8	COG3745	Flp pilus assembly protein CpaB	276
2918743318	502	82.99	115	502	66	470	1.4e-94	312.1	COG4964	Flp pilus assembly protein, secretin CpaC	455
2918743320	71	67.24	8	67	3	41	2.6e-13	44.3	COG3847	Flp pilus assembly protein, pilin Flp	58
2918743321	58	63.79	1	54	4	40	2.8e-09	31.4	COG3847	Flp pilus assembly protein, pilin Flp	58
2918743323	152	31.63	2	126	19	80	1.9e-14	48.3	COG4961	Flp pilus assembly protein TadG	185
2918743324	138	36.22	1	98	25	95	2.7e-09	31.7	COG4961	Flp pilus assembly protein TadG	185
2918743325	383	72.12	11	381	88	369	3.6e-53	175.3	COG4963	Flp pilus assembly protein, ATPase CpaE	366
2918743326	457	95.3	55	416	14	358	0.0e+00	470.3	COG4962	Pilus assembly protein, ATPase of CpaF family	355
2918743327	330	98.38	9	330	5	308	3.1e-79	260.7	COG4965	Flp pilus assembly protein TadB	309
2918743328	302	66.04	70	296	107	318	1.2e-44	147.2	COG2064	Pilus assembly protein TadC	320
2918743329	229	98.1	9	226	3	209	3.2e-42	139.1	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918743330	562	98.93	95	562	5	375	9.6e-33	108.1	COG4585	Signal transduction histidine kinase	365
2918743332	288	37.42	14	277	59	177	3.8e-29	97	COG0657	Acetyl esterase/lipase	312
2918743333	325	28.44	4	70	17	78	1.3e-34	9.2	COG0516	IMP dehydrogenase/GMP reductase	170
2918743333	325	88.53	125	316	1	193	1.3e-34	94.8	COG0516	IMP dehydrogenase/GMP reductase	170
2918743334	153	97.35	2	153	4	150	8.0e-65	212.2	COG3241	Azurin	151
2918743335	809	99.11	25	709	2	666	0.0e+00	728.8	COG0210	Superfamily I DNA or RNA helicase	655
2918743337	348	96.12	1	345	5	326	1.2e-65	213.3	COG2334	Ser/Thr protein kinase RdoA involved in Cpx stress response, MazF antagonist	331
2918743339	940	93.58	1	310	9	314	1.7e-81	268.2	COG0258	5'-3' exonuclease	310
2918743339	940	99.83	342	940	2	597	0.0e+00	796	COG0749	DNA polymerase I - 3'-5' exonuclease and polymerase domains	593
2918743340	428	97.37	27	423	10	416	1.8e-56	186.6	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
2918743341	300	98.67	1	300	1	297	5.0e-54	178.7	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918743342	406	92.53	1	403	5	363	6.6e-66	215.6	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918743343	295	96.47	1	275	7	279	1.8e-59	196	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918743344	245	99.13	4	245	2	229	8.0e-43	141.3	COG1794	Aspartate/glutamate racemase	230
2918743345	299	97.89	59	299	3	234	1.2e-71	235.4	COG0412	Dienelactone hydrolase	236
2918743346	292	94.49	1	269	8	264	6.6e-32	105.7	COG0428	Zinc transporter ZupT	266
2918743348	486	34.54	296	486	371	570	4.3e-121	126.6	COG3653	N-acyl-D-aspartate/D-glutamate deacylase	579
2918743348	486	53.71	3	299	4	314	4.3e-121	273.4	COG3653	N-acyl-D-aspartate/D-glutamate deacylase	579
2918743349	332	97.19	6	321	3	313	6.4e-117	385	COG4608	ABC-type oligopeptide transport system, ATPase component	309
2918743350	342	99.69	15	331	1	324	0.0e+00	447.6	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
2918743351	302	92.62	17	301	22	297	7.5e-89	292.2	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2918743352	311	98.74	1	311	3	316	1.8e-105	347.5	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2918743353	526	94.46	1	524	13	558	6.6e-79	260.8	COG0747	ABC-type transport system, periplasmic component	556
2918743354	481	98.18	1	481	1	486	0.0e+00	539.4	COG5476	Microcystin degradation protein MlrC, contains DUF1485 domain	488
2918743355	386	98.71	7	381	4	386	8.8e-55	181.1	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918743356	242	47.69	24	155	2	63	1.4e-12	41.6	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918743357	400	46.74	217	399	12	190	9.4e-14	24.8	COG0477	MFS family permease	338
2918743357	400	69.97	15	250	6	273	9.4e-14	24.5	COG0477	MFS family permease	338
2918743358	423	99.28	33	423	3	417	8.5e-53	174.5	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
2918743360	212	85.54	42	210	20	161	3.1e-38	125.8	COG3495	Uncharacterized protein	166
2918743361	420	35.12	228	418	262	405	2.1e-18	39.5	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
2918743361	420	48.54	1	210	4	202	2.1e-18	18.4	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
2918743362	249	84.07	28	241	25	214	5.7e-62	203.4	COG1136	ABC-type lipoprotein export system, ATPase component	226
2918743364	302	95.82	1	301	11	285	2.9e-74	241.5	COG2897	3-mercaptopyruvate sulfurtransferase SseA, contains two rhodanese domains	285
2918743365	310	95.68	1	304	8	295	6.0e-28	92.4	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918743366	380	97.07	9	380	3	367	1.5e-47	157.2	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
2918743367	88	71.6	9	88	10	67	2.5e-20	66.8	COG1722	Exonuclease VII small subunit	81
2918743368	305	79.27	13	305	10	269	2.3e-82	270.9	COG0142	Geranylgeranyl pyrophosphate synthase	322
2918743369	627	98.56	10	625	4	621	0.0e+00	910.6	COG1154	Deoxyxylulose-5-phosphate synthase	627
2918743370	360	99.72	1	357	1	362	0.0e+00	506.4	COG4663	TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component	363
2918743371	597	98.21	3	534	2	440	0.0e+00	673.1	COG4664	TRAP-type mannitol/chloroaromatic compound transport system, large permease component	447
2918743372	198	97.8	1	182	1	178	1.3e-71	234.4	COG4665	TRAP-type mannitol/chloroaromatic compound transport system, small permease component	182
2918743373	430	23.72	354	430	252	330	1.3e-29	21.9	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
2918743373	430	41.74	120	358	67	205	1.3e-29	80.8	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
2918743374	479	48.83	267	472	12	198	1.4e-41	36.8	COG0477	MFS family permease	338
2918743374	479	75.72	18	306	1	290	1.4e-41	104.3	COG0477	MFS family permease	338
2918743375	370	72.52	4	131	16	110	7.9e-21	68.3	COG2005	DNA-binding transcriptional regulator ModE (molybdenum-dependent)	130
2918743375	370	97.31	123	352	4	220	6.4e-54	176.8	COG1910	Periplasmic molybdate-binding protein/domain	223
2918743376	451	96.87	14	451	10	442	0.0e+00	465.3	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
2918743377	293	97.01	1	293	1	292	2.0e-43	143.9	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918743378	261	96.27	11	250	5	236	2.1e-48	159.2	COG2186	DNA-binding transcriptional regulator, FadR family	241
2918743379	401	96.99	13	386	6	360	5.2e-44	145.2	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918743380	286	98.34	1	286	2	297	1.6e-71	235.9	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2918743381	319	97.52	1	300	8	322	1.2e-74	246	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918743382	255	99.61	1	248	2	254	7.1e-81	265.8	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2918743383	237	99.58	4	234	2	237	6.5e-91	298.3	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2918743384	418	98.8	11	415	4	416	1.2e-55	183.8	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
2918743385	490	98.18	1	489	1	486	6.0e-112	369.3	COG5476	Microcystin degradation protein MlrC, contains DUF1485 domain	488
2918743386	251	97.36	2	228	5	225	2.3e-68	224.4	COG4662	ABC-type tungstate transport system, periplasmic component	227
2918743387	239	95.87	14	238	8	239	6.8e-49	159.1	COG1126	ABC-type polar amino acid transport system, ATPase component	240
2918743388	286	95	4	286	10	275	1.3e-95	314	COG2998	ABC-type tungstate transport system, permease component	280
2918743390	370	7.68	295	365	561	607	4.8e-53	31.8	COG3284	Transcriptional regulator of acetoin/glycerol metabolism	606
2918743390	370	42.48	4	294	24	283	4.8e-53	142	COG3284	Transcriptional regulator of acetoin/glycerol metabolism	606
2918743391	165	94.87	1	155	2	149	2.7e-64	210.2	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
2918743392	794	99.19	8	790	6	744	0.0e+00	747.2	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
2918743393	263	98.6	1	263	1	282	8.7e-71	233.5	COG1319	CO or xanthine dehydrogenase, FAD-binding subunit	284
2918743394	300	79.39	2	298	15	276	1.2e-63	209.6	COG0714	MoxR-like ATPase	329
2918743395	404	96.98	1	401	9	393	1.0e-77	256.4	COG3552	Uncharacterized conserved protein, contains von Willebrand factor type A (vWA) domain	395
2918743396	202	98.63	1	156	1	144	1.3e-39	128.6	COG3427	Carbon monoxide dehydrogenase subunit G	146
2918743397	340	98.01	6	337	3	297	1.3e-81	268.7	COG1975	Xanthine and CO dehydrogenase maturation factor, XdhC/CoxF family	278
2918743398	118	84.96	10	115	2	97	9.5e-27	87.9	COG1320	Multisubunit Na+/H+ antiporter, MnhG subunit	113
2918743399	92	97.75	4	91	3	89	5.8e-27	88.4	COG2212	Multisubunit Na+/H+ antiporter, MnhF subunit	89
2918743400	163	100	4	162	1	158	4.4e-35	115.7	COG1863	Multisubunit Na+/H+ antiporter, MnhE subunit	158
2918743401	568	99.21	17	556	2	503	2.6e-113	373.2	COG0651	Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit	504
2918743402	117	99.12	1	115	1	113	4.2e-38	124.3	COG1006	Multisubunit Na+/H+ antiporter, MnhC subunit	115
2918743403	984	83.03	798	957	19	155	7.1e-67	77.2	COG2111	Multisubunit Na+/H+ antiporter, MnhB subunit	162
2918743403	984	88.65	3	623	2	548	0.0e+00	578.2	COG1009	NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit	606
2918743403	984	98.79	611	783	2	164	7.1e-67	156.9	COG2111	Multisubunit Na+/H+ antiporter, MnhB subunit	162
2918743404	125	96.03	1	124	4	124	4.2e-31	102.2	COG0239	Fluoride ion exporter CrcB/FEX, affects chromosome condensation	126
2918743405	433	98.68	52	432	4	377	5.6e-93	306	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
2918743406	169	87.01	1	168	5	158	1.4e-21	71.3	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
2918743407	322	96.39	1	322	10	329	2.7e-59	195.7	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
2918743408	153	3.89	34	146	825	869	3.1e-05	16.8	COG0587	DNA polymerase III, alpha subunit	1139
2918743409	392	98.46	5	392	5	387	3.5e-88	290.5	COG2956	Lipopolysaccharide biosynthesis regulator YciM, contains six TPR domains and a predicted metal-binding C-terminal domain	389
2918743410	112	73.47	1	78	23	94	3.1e-11	37.6	COG5416	Uncharacterized integral membrane protein	98
2918743411	104	96.81	1	94	2	92	4.9e-35	114.3	COG0776	Bacterial nucleoid DNA-binding protein	94
2918743412	562	99.09	1	551	2	546	0.0e+00	717.7	COG0539	Ribosomal protein S1	541
2918743413	670	96.43	445	666	5	220	1.5e-72	237.9	COG0283	Cytidylate kinase	222
2918743413	670	96.51	6	445	13	427	0.0e+00	449.6	COG0128	5-enolpyruvylshikimate-3-phosphate synthase	428
2918743414	293	98.92	1	283	3	278	4.9e-81	266.6	COG0287	Prephenate dehydrogenase	279
2918743415	373	91.09	10	107	7	98	3.3e-24	79.2	COG1605	Chorismate mutase	101
2918743415	373	97.5	99	373	3	275	6.0e-89	292.4	COG0077	Prephenate dehydratase	279
2918743416	377	98.65	9	377	5	369	0.0e+00	445	COG1932	Phosphoserine aminotransferase	365
2918743417	195	76.09	2	194	44	183	2.7e-04	15	COG3184	Uncharacterized protein	183
2918743418	881	99.38	1	859	5	812	0.0e+00	1179.1	COG0188	DNA gyrase/topoisomerase IV, subunit A	804
2918743419	217	78.89	12	213	42	198	5.4e-48	158.5	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
2918743420	238	95.49	1	232	11	243	2.1e-91	300.1	COG2227	2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase	243
2918743421	222	97.75	3	222	4	220	8.4e-44	144.8	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
2918743423	531	94.42	254	528	5	258	3.5e-19	58.7	COG4797	Predicted regulatory domain of a methyltransferase	268
2918743424	578	98.72	20	578	8	545	0.0e+00	681.6	COG0405	Gamma-glutamyltranspeptidase	539
2918743425	249	97.15	1	244	3	241	4.2e-66	217.2	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
2918743426	335	30.52	198	334	103	225	4.3e-26	37.1	COG3391	DNA-binding beta-propeller fold protein YncE	381
2918743426	335	45.91	15	245	128	312	4.3e-26	48.5	COG3391	DNA-binding beta-propeller fold protein YncE	381
2918743427	271	81.72	4	271	48	266	1.7e-29	94.5	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
2918743428	324	93.95	12	316	11	274	3.2e-54	178.9	COG3000	Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily	271
2918743430	266	88.72	2	260	4	231	1.4e-54	179.6	COG1058	Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA	255
2918743431	471	99.55	3	471	2	445	0.0e+00	576.9	COG0174	Glutamine synthetase	443
2918743433	359	95.87	5	359	7	354	1.7e-119	393.6	COG3852	Signal transduction histidine kinase, nitrogen specific	363
2918743434	509	97.64	1	509	5	460	0.0e+00	595.7	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2918743436	261	99.61	1	259	1	258	1.9e-78	257.9	COG0708	Exonuclease III	261
2918743438	543	96.7	1	537	17	543	0.0e+00	455.8	COG0405	Gamma-glutamyltranspeptidase	539
2918743439	329	98.43	8	328	4	317	1.3e-76	252.4	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918743440	322	99	14	314	2	299	1.7e-40	134.2	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918743441	441	98.45	14	434	2	383	7.5e-104	342.5	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918743442	239	37.07	10	114	59	101	8.3e-17	9.1	COG3450	Predicted enzyme of the cupin superfamily	116
2918743442	239	68.97	128	236	36	115	8.3e-17	45	COG3450	Predicted enzyme of the cupin superfamily	116
2918743443	493	98.54	16	486	2	473	0.0e+00	517.3	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918743445	317	92.46	2	310	11	292	1.7e-51	169.5	COG0053	Divalent metal cation (Fe/Co/Zn/Cd) transporter	304
2918743447	501	91.19	15	253	6	243	9.7e-71	139.2	COG0467	RecA-superfamily ATPase, KaiC/GvpD/RAD55 family	260
2918743447	501	91.19	255	489	3	240	9.7e-71	91.6	COG0467	RecA-superfamily ATPase, KaiC/GvpD/RAD55 family	260
2918743448	493	78.43	6	358	83	391	2.5e-71	235.6	COG0642	Signal transduction histidine kinase	336
2918743449	337	95.06	15	320	9	316	1.0e-50	167.3	COG0392	Uncharacterized membrane protein YbhN, UPF0104 family	322
2918743450	850	96.69	548	844	5	296	1.8e-92	303.8	COG3285	Eukaryotic-type DNA primase	299
2918743450	850	97.76	74	542	1	481	1.3e-105	348.4	COG1793	ATP-dependent DNA ligase	444
2918743453	173	98.82	5	168	2	169	5.3e-48	157.6	COG0262	Dihydrofolate reductase	167
2918743454	279	98.9	7	279	4	273	3.8e-119	391.4	COG0207	Thymidylate synthase	268
2918743458	477	99.36	12	477	2	467	1.3e-114	378.2	COG0277	FAD/FMN-containing dehydrogenase	459
2918743459	135	87.02	1	130	13	126	5.7e-38	124.5	COG3308	Uncharacterized membrane protein	131
2918743460	399	90.43	2	287	11	284	3.1e-55	181.8	COG1295	Uncharacterized membrane protein, BrkB/YihY/UPF0761 family (not an RNase)	303
2918743461	112	97.14	8	112	3	104	6.0e-51	166	COG4323	Uncharacterized protein	105
2918743462	127	20	11	109	43	103	9.3e-12	39.8	COG3118	Negative regulator of GroEL, contains thioredoxin-like and TPR-like domains	304
2918743463	221	55.8	1	211	1	154	7.5e-15	49.5	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
2918743464	312	97.34	9	303	6	298	1.2e-54	180.6	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918743465	473	84.21	7	453	15	366	1.9e-39	130.3	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
2918743466	329	96.55	7	328	11	318	7.9e-86	282.5	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918743467	270	96.27	1	269	10	293	4.5e-43	142.6	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918743468	436	98.83	3	431	5	426	0.0e+00	606.1	COG2873	O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent	426
2918743469	146	42.94	67	140	2	71	7.1e-26	30.8	COG0517	CBS domain	117
2918743469	146	93.25	1	121	11	162	7.1e-26	64.4	COG0517	CBS domain	117
2918743470	326	97.49	3	326	8	318	1.5e-84	278.3	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918743471	364	95.09	9	347	8	336	1.5e-47	156.7	COG1816	Adenosine deaminase	345
2918743472	318	98.34	9	304	2	297	6.2e-53	175.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918743473	405	97.59	1	404	1	405	0.0e+00	491.3	COG4553	Poly-beta-hydroxyalkanoate depolymerase	415
2918743474	218	92.09	5	217	4	201	6.8e-28	92.6	COG0625	Glutathione S-transferase	211
2918743475	273	99.19	14	265	2	245	9.4e-39	127.2	COG1414	DNA-binding transcriptional regulator, IclR family	246
2918743476	331	99.06	6	330	3	318	3.2e-79	260.9	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918743477	438	48.14	22	324	27	207	7.0e-37	122	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
2918743478	115	86.67	5	115	10	113	1.7e-31	103.2	COG3805	Aromatic ring-cleaving dioxygenase	120
2918743480	324	76.34	24	319	14	226	9.8e-10	33.6	COG0500	SAM-dependent methyltransferase	257
2918743481	141	85.4	1	123	4	120	2.3e-16	54.5	COG3011	Predicted thiol-disulfide oxidoreductase YuxK, DCC family	137
2918743482	200	95.48	1	175	2	170	1.0e-41	137.2	COG1510	DNA-binding transcriptional regulator GbsR, MarR family	177
2918743483	364	96.97	50	350	6	293	5.5e-90	296	COG1533	DNA repair photolyase	297
2918743484	168	97.52	9	167	1	157	9.5e-50	162.8	COG3265	Gluconate kinase	161
2918743485	474	98.95	3	473	2	470	0.0e+00	708.4	COG0362	6-phosphogluconate dehydrogenase	473
2918743486	202	39.23	34	199	11	152	1.3e-15	52	COG0349	Ribonuclease D	361
2918743487	128	90.91	1	117	9	118	1.5e-24	80.6	COG3070	Transcriptional regulator of competence genes, TfoX/Sxy family	121
2918743488	129	99.32	1	129	1	145	1.1e-20	69.9	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2918743489	167	54.5	4	158	77	179	2.4e-12	41.7	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
2918743490	291	98.15	1	291	4	321	5.6e-75	247.2	COG0627	S-formylglutathione hydrolase FrmB	316
2918743491	308	96.95	7	301	7	292	3.1e-33	110.2	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918743492	368	99.73	1	368	1	365	0.0e+00	565.5	COG1062	Zn-dependent alcohol dehydrogenase	366
2918743493	212	89.3	2	204	2	193	9.7e-41	134.5	COG0625	Glutathione S-transferase	211
2918743494	287	9.84	7	54	27	63	1.2e-32	4.3	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
2918743494	287	68.88	47	287	114	372	1.2e-32	103.5	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
2918743495	225	97.2	5	118	3	106	2.6e-17	57	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
2918743496	146	94.52	2	146	2	139	8.3e-66	214.7	COG0757	3-dehydroquinate dehydratase	146
2918743497	515	96.37	13	514	7	484	0.0e+00	715.3	COG2719	Stage V sporulation protein SpoVR/YcgB, involved in spore cortex formation (function unknown)	495
2918743498	430	98.35	4	429	3	419	0.0e+00	502.8	COG2718	Uncharacterized conserved protein YeaH/YhbH, required for sporulation, DUF444 family	423
2918743499	640	99.85	1	640	1	649	0.0e+00	961.6	COG2766	Predicted Ser/Thr protein kinase	649
2918743500	378	99.22	2	378	2	383	0.0e+00	487.6	COG0484	DnaJ-class molecular chaperone with C-terminal Zn finger domain	371
2918743501	646	99.17	1	606	5	605	0.0e+00	846.7	COG0443	Molecular chaperone DnaK (HSP70)	579
2918743502	179	88.27	2	179	23	195	1.6e-56	185.8	COG0576	Molecular chaperone GrpE (heat shock protein)	193
2918743503	116	51.94	1	116	99	205	6.6e-54	177.7	COG0545	FKBP-type peptidyl-prolyl cis-trans isomerase	205
2918743504	150	82.5	1	108	10	108	1.9e-15	49.9	COG1733	DNA-binding transcriptional regulator, HxlR family	120
2918743505	283	98.84	8	277	3	257	1.1e-76	251.7	COG0688	Phosphatidylserine decarboxylase	239
2918743506	330	97.18	3	329	9	318	2.0e-85	281.2	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918743507	363	98.84	28	361	4	345	4.1e-80	264.1	COG2706	6-phosphogluconolactonase, cycloisomerase 2 family	346
2918743508	326	97.81	10	325	5	316	3.3e-88	290.3	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918743509	253	99.25	2	251	2	267	3.2e-69	228	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918743510	529	99.75	109	529	2	398	0.0e+00	491	COG2721	Altronate dehydratase	381
2918743511	431	99.74	48	428	1	378	2.6e-123	406.1	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
2918743512	162	88.14	1	161	6	161	1.1e-36	120.4	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
2918743513	325	98.8	1	325	2	329	9.0e-112	368.2	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
2918743514	296	95.47	1	294	15	309	3.2e-79	260.7	COG3386	Sugar lactone lactonase YvrE	307
2918743515	277	59.19	11	243	3	192	1.2e-30	101.5	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2918743516	273	97.51	26	264	5	239	7.5e-65	213.1	COG2186	DNA-binding transcriptional regulator, FadR family	241
2918743517	324	95.92	5	323	12	317	1.4e-80	265.4	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918743518	57	16.05	7	57	4	51	4.8e-10	33.4	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
2918743519	30	7.61	1	30	1	30	1.2e-15	51.2	COG0050	Translation elongation factor EF-Tu, a GTPase	394
2918743523	239	91.89	16	237	6	209	9.6e-69	225.9	COG0692	Uracil DNA glycosylase	223
2918743524	266	99.61	5	266	1	253	7.4e-95	311.5	COG0134	Indole-3-glycerol phosphate synthase	254
2918743525	341	98.82	1	339	3	338	0.0e+00	437.9	COG0547	Anthranilate phosphoribosyltransferase	338
2918743526	219	98.56	2	212	2	206	5.7e-61	199.9	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
2918743527	352	99.13	7	351	2	341	1.1e-107	354.5	COG2008	Threonine aldolase	342
2918743528	194	97.91	1	194	2	188	1.7e-74	244	COG0512	Anthranilate/para-aminobenzoate synthase component II	191
2918743530	500	98.93	19	499	2	463	0.0e+00	537.8	COG0147	Anthranilate/para-aminobenzoate synthases component I	462
2918743532	236	95.95	9	236	4	216	1.2e-57	190	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
2918743538	465	98.68	15	456	2	451	1.4e-83	275.8	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
2918743539	160	65	49	155	24	101	5.8e-05	17	COG2044	Predicted peroxiredoxin	120
2918743540	348	97.48	6	302	3	273	2.1e-52	172.5	COG0388	Predicted amidohydrolase	274
2918743541	373	98.23	18	369	4	336	2.5e-52	172.2	COG2516	Biotin synthase-related protein, radical SAM superfamily	339
2918743542	186	53.59	21	166	48	129	9.2e-08	26.5	COG1246	N-acetylglutamate synthase or related acetyltransferase, GNAT family	153
2918743543	332	96.6	2	327	3	315	1.9e-81	268.1	COG2144	Selenophosphate synthetase-related protein	324
2918743545	441	91.48	3	440	6	413	1.5e-55	183.3	COG2072	Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD	443
2918743546	227	97.16	1	224	1	205	7.6e-54	176.9	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918743547	441	60.23	20	213	84	242	2.8e-14	47.3	COG3455	Type VI protein secretion system component VasF	262
2918743548	372	29.72	3	368	49	402	2.7e-32	106	COG3523	Type VI protein secretion system component VasK	1188
2918743549	170	92.55	16	170	7	155	2.5e-40	132.3	COG3521	Predicted component of the type VI protein secretion system	159
2918743550	343	16.43	235	339	281	338	6.6e-38	36.5	COG3515	Predicted component of the type VI protein secretion system	346
2918743550	343	32.01	9	213	14	126	6.6e-38	90.8	COG3515	Predicted component of the type VI protein secretion system	346
2918743551	172	97.63	2	169	2	166	1.8e-68	223.9	COG3516	Predicted component of the type VI protein secretion system	169
2918743552	497	97.17	1	495	14	494	0.0e+00	758.3	COG3517	Predicted component of the type VI protein secretion system	495
2918743553	160	99.37	1	160	1	157	4.6e-41	134.9	COG3157	Type VI protein secretion system component Hcp (secreted cytotoxin)	162
2918743556	279	88.6	5	253	16	256	1.5e-41	136.8	COG0631	Serine/threonine protein phosphatase PrpC	262
2918743557	551	49.07	1	230	6	217	1.3e-70	58.5	COG3456	Predicted component of the type VI protein secretion system, contains a FHA domain	430
2918743557	551	64.35	242	550	152	429	1.3e-70	176.3	COG3456	Predicted component of the type VI protein secretion system, contains a FHA domain	430
2918743562	345	33.09	12	311	222	358	1.1e-10	34.8	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
2918743563	370	97.82	1	368	1	359	9.3e-123	404.4	COG5351	Uncharacterized protein	367
2918743565	792	94.64	2	750	22	568	0.0e+00	476.1	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
2918743568	353	36.65	147	243	73	164	7.4e-53	47.1	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2918743568	353	39.04	236	345	83	180	7.4e-53	65.7	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2918743568	353	63.35	4	174	48	206	7.4e-53	78	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2918743569	865	22.71	792	853	108	164	2.4e-50	36.6	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2918743569	865	51.79	523	667	84	213	2.4e-50	75	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2918743569	865	74.9	620	806	49	236	2.4e-50	83.8	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2918743570	938	96.54	2	626	18	575	0.0e+00	495.9	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
2918743571	909	99.13	12	909	2	799	0.0e+00	960.6	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
2918743572	444	22.65	124	198	8	72	4.1e-67	5	COG4976	Predicted methyltransferase, contains TPR repeat	287
2918743572	444	25.09	55	143	13	84	4.1e-67	12.5	COG4976	Predicted methyltransferase, contains TPR repeat	287
2918743572	444	93.03	160	443	18	284	4.1e-67	206.8	COG4976	Predicted methyltransferase, contains TPR repeat	287
2918743573	359	93.13	10	345	18	329	2.9e-89	294	COG3520	Predicted component of the type VI protein secretion system	335
2918743574	630	99.68	1	630	1	619	0.0e+00	637.2	COG3519	Type VI protein secretion system component VasA	621
2918743575	171	96.18	4	165	2	152	8.4e-34	110.9	COG3518	Predicted component of the type VI protein secretion system	157
2918743576	266	95.97	1	266	7	268	1.0e-81	269	COG4455	Protein of avirulence locus involved in temperature-dependent protein secretion	273
2918743581	531	29.55	387	500	265	376	7.3e-67	128.9	COG2821	Membrane-bound lytic murein transglycosylase	373
2918743581	531	54.35	17	316	21	226	7.3e-67	90.6	COG2821	Membrane-bound lytic murein transglycosylase	373
2918743582	641	63.4	45	481	3	300	1.1e-31	105.1	COG0515	Serine/threonine protein kinase	384
2918743584	203	59.91	2	160	7	142	4.1e-29	96.2	COG3913	Uncharacterized protein	227
2918743585	1199	99.08	2	1199	9	1188	0.0e+00	1066.1	COG3523	Type VI protein secretion system component VasK	1188
2918743586	444	84.85	13	280	38	261	3.0e-79	260.5	COG3455	Type VI protein secretion system component VasF	262
2918743587	443	100	1	443	1	446	0.0e+00	514.2	COG3522	Predicted component of the type VI protein secretion system	446
2918743588	102	11.48	9	60	167	190	1.5e-02	1.5	COG3932	Uncharacterized conserved protein	209
2918743588	102	20.57	33	95	43	85	1.5e-02	12.6	COG3932	Uncharacterized conserved protein	209
2918743589	347	93.02	3	309	6	285	9.9e-42	137.4	COG3221	ABC-type phosphate/phosphonate transport system, periplasmic component	299
2918743590	339	97.01	1	304	5	296	1.0e-49	163.9	COG3221	ABC-type phosphate/phosphonate transport system, periplasmic component	299
2918743591	629	84.01	92	479	55	385	2.5e-62	206.4	COG0642	Signal transduction histidine kinase	336
2918743592	331	68.94	81	330	91	312	1.7e-12	41.2	COG2984	ABC-type uncharacterized transport system, periplasmic component	322
2918743593	665	83.25	71	528	63	390	2.1e-54	179.2	COG0642	Signal transduction histidine kinase	336
2918743595	259	12.81	6	204	80	125	8.0e-03	9.9	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
2918743596	365	65.36	2	318	20	253	1.2e-23	78.3	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
2918743598	576	90.71	9	576	53	560	1.3e-96	319.1	COG2831	Hemolysin activation/secretion protein	554
2918743599	716	78.87	227	711	90	425	3.8e-53	175.5	COG4995	Uncharacterized conserved protein, contains CHAT domain	420
2918743600	728	98.4	22	528	3	495	0.0e+00	731.7	COG0753	Catalase	496
2918743602	272	49.11	68	269	138	303	3.9e-38	126.4	COG1305	Transglutaminase-like enzyme, putative cysteine protease	319
2918743603	302	96.36	4	299	7	297	6.8e-99	325.2	COG3285	Eukaryotic-type DNA primase	299
2918743604	341	97.85	8	295	4	276	2.1e-85	280.5	COG1273	Non-homologous end joining protein Ku, dsDNA break repair	278
2918743605	331	12.12	188	306	202	241	5.8e-18	1.9	COG3608	Predicted deacylase	331
2918743605	331	36.06	3	174	38	156	5.8e-18	55.6	COG3608	Predicted deacylase	331
2918743607	232	97.27	3	229	4	217	4.2e-87	285.4	COG0036	Pentose-5-phosphate-3-epimerase	220
2918743608	131	91.27	1	122	6	120	5.2e-50	163.2	COG2967	Uncharacterized protein affecting Mg2+/Co2+ transport	126
2918743609	657	95.57	1	657	18	664	0.0e+00	498.7	COG4389	Site-specific recombinase	677
2918743610	423	91.5	21	412	9	374	1.0e-13	45	COG0475	Kef-type K+ transport system, membrane component KefB	397
2918743611	399	97.02	36	397	2	359	3.6e-120	395.9	COG2170	Gamma-glutamyl:cysteine ligase YbdK, ATP-grasp superfamily	369
2918743612	322	95.69	1	322	11	321	5.3e-99	325.9	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
2918743613	209	95.15	5	184	5	200	2.9e-32	106.5	COG1335	Nicotinamidase-related amidase	205
2918743614	319	99.38	1	318	3	320	2.1e-99	327	COG0611	Thiamine monophosphate kinase	317
2918743616	494	48.83	281	492	8	194	3.4e-26	11.2	COG0477	MFS family permease	338
2918743616	494	80.16	28	307	5	311	3.4e-26	79.9	COG0477	MFS family permease	338
2918743617	175	98.14	3	173	3	160	1.4e-36	120.7	COG1267	Phosphatidylglycerophosphatase A	160
2918743618	180	95.71	10	170	5	160	4.1e-61	199.6	COG1546	Nicotinamide mononucleotide (NMN) deamidase PncC	162
2918743620	104	87.88	2	95	10	96	6.7e-21	68.9	COG2388	Predicted acetyltransferase, GNAT superfamily	99
2918743621	413	94.94	7	410	12	386	1.9e-19	63.9	COG2814	Predicted arabinose efflux permease, MFS family	394
2918743622	260	15.67	22	104	23	56	4.7e-12	4	COG3318	Uncharacterized conserved protein YecA, UPF0149 family, contains C-terminal Zn-binding SEC-C motif	216
2918743622	260	51.15	127	260	106	216	4.7e-12	36.3	COG3318	Uncharacterized conserved protein YecA, UPF0149 family, contains C-terminal Zn-binding SEC-C motif	216
2918743623	575	97.14	34	517	14	488	6.7e-123	404.5	COG0069	Glutamate synthase domain 2	485
2918743624	306	72.2	101	273	47	194	1.2e-03	12.2	COG3642	tRNA A-37 threonylcarbamoyl transferase component Bud32	204
2918743625	84	7.77	5	73	218	270	5.9e-04	12.3	COG2216	High-affinity K+ transport system, ATPase chain B	681
2918743627	81	10.98	51	78	120	137	1.3e-03	3.9	COG5472	Predicted small integral membrane protein	164
2918743627	81	27.44	2	60	105	149	1.3e-03	11.7	COG5472	Predicted small integral membrane protein	164
2918743628	142	83.8	8	137	3	121	8.1e-13	43.3	COG1569	Predicted nucleic acid-binding protein, contains PIN domain	142
2918743629	412	98.95	2	410	3	379	1.3e-110	364.5	COG0116	23S rRNA G2445 N2-methylase RlmL	381
2918743630	208	96.13	20	203	5	178	6.2e-47	154	COG3038	Cytochrome b561	181
2918743631	192	97.93	1	186	1	189	8.8e-36	117.8	COG2353	Polyisoprenoid-binding periplasmic protein YceI	192
2918743632	211	95.34	1	210	8	191	7.4e-47	150.7	COG2353	Polyisoprenoid-binding periplasmic protein YceI	192
2918743633	187	86.54	1	185	26	205	1.9e-38	126.4	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
2918743634	535	84.54	26	529	45	454	3.9e-78	257.6	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
2918743635	530	99.55	1	530	1	446	0.0e+00	477.9	COG1508	DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog	444
2918743636	264	98.77	15	264	4	243	2.2e-113	371.9	COG1137	ABC-type lipopolysaccharide export system, ATPase component	243
2918743637	243	91.33	20	209	11	168	2.8e-32	105.9	COG1934	Lipopolysaccharide export system protein LptA	173
2918743638	215	16	47	101	5	40	4.0e-14	6.8	COG2761	Predicted dithiol-disulfide isomerase, DsbA family	225
2918743638	215	41.33	93	203	106	198	4.0e-14	40.4	COG2761	Predicted dithiol-disulfide isomerase, DsbA family	225
2918743639	246	14.61	1	58	13	51	4.4e-24	4.3	COG3087	Cell division protein FtsN	264
2918743639	246	46.44	110	246	140	263	4.4e-24	80.5	COG3087	Cell division protein FtsN	264
2918743640	561	99.48	2	561	4	581	0.0e+00	550.5	COG0018	Arginyl-tRNA synthetase	577
2918743641	135	26.88	1	131	11	121	1.9e-02	8.5	COG2133	Glucose/arabinose dehydrogenase, beta-propeller fold	399
2918743642	674	96.34	3	428	8	376	4.1e-01	8.7	COG0477	MFS family permease	338
2918743643	150	99.33	1	150	1	149	2.6e-45	148.8	COG3556	Uncharacterized membrane protein	150
2918743644	323	98.34	2	319	2	297	1.1e-63	210.4	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918743645	396	97.76	1	392	7	398	5.3e-125	411.9	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2918743646	312	63.68	4	283	3	265	8.1e-51	167.7	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
2918743647	246	97.56	21	246	2	241	4.6e-40	129.6	COG1414	DNA-binding transcriptional regulator, IclR family	246
2918743648	225	96.1	1	225	6	227	8.7e-32	105.5	COG1011	FMN phosphatase YigB, HAD superfamily	229
2918743649	724	99.13	4	724	3	573	0.0e+00	722.3	COG2225	Malate synthase	545
2918743650	412	50.65	199	411	14	207	3.6e-15	14.8	COG0477	MFS family permease	338
2918743650	412	70.76	7	244	5	275	3.6e-15	39.1	COG0477	MFS family permease	338
2918743652	308	98.67	14	308	2	298	9.5e-52	171.2	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918743654	392	99.75	1	392	1	393	6.2e-121	398.7	COG0183	Acetyl-CoA acetyltransferase	392
2918743655	268	98.87	2	265	4	265	5.9e-73	240.1	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918743656	387	97.24	4	387	7	394	3.4e-120	396.3	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918743657	418	90.76	4	381	8	331	7.6e-52	170.8	COG0205	6-phosphofructokinase	347
2918743659	435	95.99	29	420	4	338	4.1e-127	418	COG4307	Uncharacterized protein	349
2918743660	494	47.59	22	242	9	196	3.5e-30	85.2	COG2814	Predicted arabinose efflux permease, MFS family	394
2918743660	494	48.35	250	466	172	362	3.5e-30	25	COG2814	Predicted arabinose efflux permease, MFS family	394
2918743661	379	93.72	10	378	9	351	1.4e-32	107.6	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918743662	255	97.27	1	254	1	249	8.7e-87	285.4	COG0121	Predicted glutamine amidotransferase	252
2918743663	755	98.36	12	755	14	795	3.4e-63	209.1	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2918743664	432	40.86	1	201	5	185	3.2e-53	87.8	COG3182	Uncharacterized iron-regulated membrane protein	442
2918743664	432	53.5	193	425	161	397	3.2e-53	90.4	COG3182	Uncharacterized iron-regulated membrane protein	442
2918743665	318	99.05	2	317	3	314	4.8e-86	283	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
2918743666	421	96.28	1	391	13	400	0.0e+00	461.5	COG3135	Predicted benzoate:H+ symporter BenE	402
2918743668	307	40.67	15	232	75	183	1.4e-08	28.2	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
2918743669	255	93.1	22	247	7	222	6.7e-57	187.1	COG1802	DNA-binding transcriptional regulator, GntR family	230
2918743670	623	98.25	2	623	12	627	0.0e+00	832.6	COG3158	K+ transporter	627
2918743672	431	99.52	6	431	3	417	0.0e+00	560.4	COG0014	Gamma-glutamyl phosphate reductase	417
2918743673	357	93.71	3	346	4	316	7.0e-67	220.6	COG1466	DNA polymerase III, delta subunit	334
2918743674	173	86.74	9	173	8	164	4.4e-31	102.4	COG2980	Outer membrane lipoprotein LptE/RlpB (LPS assembly)	178
2918743675	876	99.51	1	876	4	822	0.0e+00	980.4	COG0495	Leucyl-tRNA synthetase	814
2918743676	325	97.49	1	323	7	317	9.1e-87	285.6	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918743678	202	97.85	11	196	3	184	2.9e-33	110.1	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
2918743679	173	88.6	1	173	9	179	2.7e-36	119.9	COG4950	N-terminal domain of uncharacterized protein YciW (function unknown)	193
2918743680	491	95.96	42	490	7	434	2.6e-67	222.4	COG2072	Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD	443
2918743681	557	97.1	15	523	1	502	3.1e-129	427.1	COG0366	Glycosidase	505
2918743682	723	16.75	1	105	5	110	0.0e+00	3.6	COG0296	1,4-alpha-glucan branching enzyme	628
2918743682	723	99.05	101	722	5	631	0.0e+00	842	COG0296	1,4-alpha-glucan branching enzyme	628
2918743683	693	96.73	1	693	13	693	0.0e+00	735.3	COG1523	Pullulanase/glycogen debranching enzyme	697
2918743684	437	97.96	19	436	3	386	0.0e+00	509	COG0448	ADP-glucose pyrophosphorylase	393
2918743685	495	98.77	1	494	1	483	0.0e+00	517.8	COG0297	Glycogen synthase	487
2918743686	827	99.34	8	823	5	751	0.0e+00	965.8	COG0058	Glucan phosphorylase	750
2918743687	147	93.04	1	145	6	152	5.4e-32	105.6	COG1522	DNA-binding transcriptional regulator, Lrp family	154
2918743688	300	95.68	1	293	8	295	1.7e-41	137.1	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918743689	159	94.24	15	151	7	137	1.5e-43	142.7	COG0848	Biopolymer transport protein ExbD	137
2918743690	235	94.44	6	218	3	206	3.2e-48	159.1	COG0811	Biopolymer transport protein ExbB/TolQ	216
2918743691	284	98.88	19	283	4	267	9.2e-102	334.5	COG0289	Dihydrodipicolinate reductase	266
2918743692	186	86.67	3	166	4	133	8.2e-29	95.1	COG2913	Outer membrane protein assembly factor BamE, lipoprotein component of the BamABCDE complex	147
2918743693	139	92.41	1	139	9	142	9.1e-46	150	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
2918743694	319	96.75	4	317	7	304	1.6e-91	301.3	COG1493	Serine kinase of the HPr protein, regulates carbohydrate metabolism	308
2918743695	155	97.37	3	152	3	150	3.5e-34	112.3	COG1762	Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type)	152
2918743696	109	91.82	1	108	1	101	3.1e-35	115.4	COG1544	Ribosome-associated translation inhibitor RaiA	110
2918743697	705	98.96	25	682	2	665	0.0e+00	495.3	COG0210	Superfamily I DNA or RNA helicase	655
2918743698	328	95.73	3	327	15	328	9.6e-64	209.7	COG0598	Mg2+ and Co2+ transporter CorA	322
2918743699	265	97.05	7	256	5	234	1.9e-66	218.3	COG0775	Nucleoside phosphorylase	234
2918743700	546	97.75	10	546	9	573	0.0e+00	432.5	COG0747	ABC-type transport system, periplasmic component	556
2918743701	348	97.5	8	314	4	315	4.2e-111	365.7	COG4608	ABC-type oligopeptide transport system, ATPase component	309
2918743702	345	99.08	4	321	1	322	1.5e-125	413	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
2918743703	300	95.97	8	300	11	296	2.2e-103	339.8	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2918743704	334	99.37	1	334	1	316	2.1e-125	413	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2918743705	559	97.01	15	559	6	556	0.0e+00	469.3	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2918743706	475	100	1	474	1	470	0.0e+00	720.1	COG1282	NAD/NADP transhydrogenase beta subunit	463
2918743707	109	30.3	1	108	99	208	2.5e-31	104	COG3288	NAD/NADP transhydrogenase alpha subunit	356
2918743708	376	99.72	2	372	2	363	0.0e+00	481.9	COG3288	NAD/NADP transhydrogenase alpha subunit	356
2918743709	237	98.71	1	227	1	229	3.1e-58	191.4	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918743711	159	84.88	1	147	14	159	6.4e-12	40.4	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2918743712	369	98.6	1	369	2	353	0.0e+00	445.5	COG0482	tRNA U34 2-thiouridine synthase MnmA/TrmU, contains the PP-loop ATPase domain	356
2918743713	328	96.79	10	327	5	336	2.0e-70	232	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2918743716	237	93.42	2	236	11	237	2.6e-61	201.7	COG0217	Transcriptional and/or translational regulatory protein YebC/TACO1	241
2918743717	142	94.81	8	141	4	131	2.8e-31	102.9	COG3791	Uncharacterized conserved protein	133
2918743718	658	96.27	199	651	15	375	1.8e-55	182.5	COG4585	Signal transduction histidine kinase	365
2918743719	180	100	1	180	1	171	3.0e-54	178.7	COG0629	Single-stranded DNA-binding protein	167
2918743720	463	95.51	6	435	6	430	3.0e-80	264.5	COG0038	H+/Cl- antiporter ClcA	443
2918743721	1028	35.49	683	1028	606	939	0.0e+00	592.7	COG0178	Excinuclease UvrABC ATPase subunit	935
2918743721	1028	64.29	31	664	3	607	0.0e+00	820.7	COG0178	Excinuclease UvrABC ATPase subunit	935
2918743722	296	97.01	1	295	5	296	3.9e-35	116.1	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918743723	251	97.49	6	249	5	237	3.1e-67	221	COG2188	DNA-binding transcriptional regulator, GntR family	236
2918743724	1083	81.47	1	406	4	412	2.0e-58	192.5	COG1070	Sugar (pentulose or hexulose) kinase	502
2918743724	1083	97.77	506	1056	11	535	2.5e-109	358.7	COG0578	Glycerol-3-phosphate dehydrogenase	532
2918743725	346	95.72	1	337	11	323	2.3e-58	192.2	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
2918743726	508	98.6	3	502	6	499	0.0e+00	630.2	COG1129	ABC-type sugar transport system, ATPase component	500
2918743727	338	97.18	23	338	6	315	2.4e-91	300.5	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
2918743728	330	98.12	5	329	1	314	9.0e-94	308.5	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
2918743729	283	97.4	1	272	8	269	2.0e-68	225.3	COG1830	Fructose-bisphosphate aldolase class Ia, DhnA family	265
2918743730	1569	7.3	110	189	149	175	3.1e-06	1.9	COG5276	Uncharacterized conserved protein	370
2918743730	1569	13.41	1312	1431	61	82	6.5e-06	8.5	COG2010	Cytochrome c, mono- and diheme variants	150
2918743730	1569	40.54	202	447	140	289	3.1e-06	16.1	COG5276	Uncharacterized conserved protein	370
2918743730	1569	52.44	1146	1325	35	120	6.5e-06	11.9	COG2010	Cytochrome c, mono- and diheme variants	150
2918743731	79	85	2	77	12	79	1.2e-17	58.4	COG0636	FoF1-type ATP synthase, membrane subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K	79
2918743732	402	97.27	24	385	5	360	1.7e-46	153.4	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918743733	306	97.01	3	306	5	296	1.4e-75	249.1	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2918743734	326	96.59	5	313	9	320	6.7e-75	246.8	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918743735	251	98.43	1	245	5	254	4.9e-88	289.3	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2918743736	239	99.58	5	239	2	237	5.8e-79	259.1	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2918743737	403	46.74	212	402	14	192	3.6e-33	8.7	COG0477	MFS family permease	338
2918743737	403	62.66	5	242	8	247	3.6e-33	104.7	COG0477	MFS family permease	338
2918743738	317	84.09	180	314	17	127	2.7e-27	89.4	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918743739	84	11.9	2	76	11	77	1.9e-14	47.4	COG0659	Sulfate permease or related transporter, MFS superfamily	554
2918743740	237	98.51	3	235	4	267	3.1e-54	178.9	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918743741	202	97.21	1	202	1	209	4.9e-34	112.7	COG0625	Glutathione S-transferase	211
2918743742	572	37.63	329	569	323	535	7.4e-34	23.4	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
2918743742	572	40.11	6	368	5	231	7.4e-34	81.1	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
2918743743	247	97.39	4	242	6	266	2.3e-65	215.4	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918743744	249	99.25	1	247	2	267	1.9e-70	232	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918743745	239	99.58	3	239	2	237	7.5e-94	307.9	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2918743746	258	99.21	2	249	3	254	2.7e-96	316.3	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2918743747	327	96.59	9	314	8	319	8.7e-83	272.7	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918743748	300	97.34	6	298	5	297	2.9e-62	205.4	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2918743749	404	95.36	8	403	9	357	6.8e-44	144.8	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918743750	259	98.51	6	257	4	267	2.1e-62	205.7	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918743751	238	90.52	1	223	14	223	1.2e-49	163.3	COG1802	DNA-binding transcriptional regulator, GntR family	230
2918743752	292	96.9	9	292	6	286	2.4e-94	310.2	COG1946	Acyl-CoA thioesterase	289
2918743754	324	97.18	1	322	8	317	8.0e-66	216.8	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918743755	329	96.55	6	327	7	314	4.8e-70	230.6	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918743756	427	94.15	8	395	4	373	3.0e-66	218.9	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2918743757	234	78.39	14	234	56	269	9.5e-73	239.6	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
2918743758	361	96.87	6	361	10	349	0.0e+00	493	COG3435	Gentisate 1,2-dioxygenase	351
2918743759	298	98.01	4	297	1	295	4.6e-49	162.2	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918743760	149	85.99	1	146	14	148	1.2e-46	152.7	COG1607	Acyl-CoA hydrolase	157
2918743761	168	87.96	15	128	5	99	2.6e-06	21	COG3937	Polyhydroxyalkanoate synthesis regulator phasin	108
2918743762	237	85.65	1	237	6	184	4.0e-22	74	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918743763	279	53.8	21	277	109	306	3.3e-05	18.2	COG0457	Tetratricopeptide (TPR) repeat	291
2918743764	85	94.25	3	85	2	83	8.9e-31	100.5	COG4281	Acyl-CoA-binding protein	87
2918743765	412	98.75	3	411	6	401	0.0e+00	452.5	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2918743766	296	79.55	158	292	21	125	7.7e-21	68.4	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918743767	306	93.88	1	306	9	315	5.9e-78	256.6	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
2918743768	506	98.8	3	502	5	499	0.0e+00	630.5	COG1129	ABC-type sugar transport system, ATPase component	500
2918743769	326	95.61	17	326	6	310	3.4e-107	352.6	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
2918743770	378	100	20	372	1	353	5.0e-91	299.5	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
2918743771	508	99.4	1	508	3	501	0.0e+00	448.5	COG1070	Sugar (pentulose or hexulose) kinase	502
2918743772	245	99.25	5	244	2	267	7.8e-58	190.8	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918743774	376	89.36	3	359	37	372	3.2e-111	366.3	COG4324	Predicted aminopeptidase	376
2918743775	693	94.81	2	686	42	809	0.0e+00	493.8	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
2918743776	374	94.26	7	373	9	353	5.3e-47	155.1	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918743778	400	96.69	1	396	12	391	0.0e+00	431.7	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
2918743779	395	97.42	11	389	6	269	9.2e-74	243	COG0584	Glycerophosphoryl diester phosphodiesterase	257
2918743780	388	96.17	2	384	11	412	5.3e-70	231	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
2918743781	420	98.55	8	419	6	414	2.7e-115	380.5	COG2733	Uncharacterized membrane-anchored protein YjiN, DUF445 family	415
2918743782	552	7.65	517	552	192	218	1.7e-17	6	COG4257	Streptogramin lyase	353
2918743782	552	9.92	461	514	191	225	1.7e-17	5.4	COG4257	Streptogramin lyase	353
2918743782	552	18.7	34	123	184	249	1.7e-17	4.1	COG4257	Streptogramin lyase	353
2918743782	552	19.26	369	458	62	129	1.7e-17	16	COG4257	Streptogramin lyase	353
2918743782	552	20.11	259	342	67	137	1.7e-17	15	COG4257	Streptogramin lyase	353
2918743782	552	33.14	142	268	208	324	1.7e-17	9.5	COG4257	Streptogramin lyase	353
2918743783	257	95.76	8	241	5	230	9.5e-52	170	COG3300	MHYT domain, NO-binding membrane sensor	236
2918743784	386	97.49	1	383	5	393	6.9e-103	339.3	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918743785	252	72.43	2	251	10	227	3.0e-59	191.5	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
2918743786	423	80.38	1	422	29	446	0.0e+00	458.2	COG0513	Superfamily II DNA and RNA helicase	513
2918743787	121	91.43	15	121	6	101	7.4e-28	91.1	COG0023	Translation initiation factor 1 (eIF-1/SUI1)	104
2918743788	77	98.59	1	71	1	70	2.0e-33	109	COG3530	Uncharacterized conserved protein, DUF3820 family	71
2918743790	149	43.24	91	117	15	30	3.2e-02	2.4	COG4890	Predicted outer membrane lipoprotein	37
2918743790	149	62.16	27	59	3	25	3.2e-02	9.8	COG4890	Predicted outer membrane lipoprotein	37
2918743791	503	99.01	1	503	1	499	0.0e+00	677.8	COG3333	TctA family transporter	504
2918743792	448	87.31	251	447	7	178	1.5e-76	48.4	COG2059	Chromate transport protein ChrA	195
2918743792	448	88.32	11	205	6	179	1.5e-76	207.9	COG2059	Chromate transport protein ChrA	195
2918743793	252	97.3	1	252	5	256	1.6e-43	143.5	COG0730	Uncharacterized membrane protein YfcA	258
2918743795	557	98.38	4	554	2	547	0.0e+00	551.8	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
2918743796	409	98.23	15	409	6	394	8.5e-122	401.5	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
2918743797	301	98.59	2	277	3	281	1.7e-46	153.3	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918743798	512	97.29	18	499	12	477	0.0e+00	449.8	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918743799	286	97.97	9	255	3	243	1.2e-53	176.1	COG1414	DNA-binding transcriptional regulator, IclR family	246
2918743800	356	97.73	1	350	4	348	7.2e-127	418	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
2918743801	283	94.79	1	281	5	277	3.0e-80	264.2	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
2918743802	264	91.39	1	258	14	257	4.8e-76	250.1	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
2918743803	102	7.26	17	101	6	76	1.2e-03	11.3	COG3383	Predicted molibdopterin-dependent oxidoreductase YjgC	978
2918743804	471	8.6	6	59	150	186	3.5e-29	26.4	COG0446	NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase	415
2918743804	471	85.58	56	448	42	409	3.5e-29	76.4	COG0446	NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase	415
2918743805	376	98.45	5	376	3	384	1.4e-71	236.4	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918743806	357	97.01	55	357	2	293	3.8e-34	112.6	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
2918743807	542	97.54	1	542	5	558	0.0e+00	456.7	COG2303	Choline dehydrogenase or related flavoprotein	542
2918743808	296	97.01	1	296	2	293	6.0e-47	155.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918743809	388	97.38	115	386	7	266	1.3e-83	274.7	COG0767	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, permease component MlaE	267
2918743810	272	94.3	1	262	6	253	1.0e-87	288.2	COG1127	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, ATPase component MlaF	263
2918743811	323	77.57	1	317	1	287	7.7e-38	124.8	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2918743812	223	94.15	3	221	11	203	1.2e-15	52	COG3218	ABC-type uncharacterized transport system, auxiliary component	205
2918743813	73	38.19	3	72	23	77	3.9e-04	15.3	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
2918743814	170	92.59	11	147	7	131	4.1e-27	89.2	COG3791	Uncharacterized conserved protein	133
2918743815	248	96.5	12	247	3	250	6.9e-58	190.1	COG0846	NAD-dependent protein deacetylase, SIR2 family	250
2918743816	287	99.59	15	274	1	245	7.4e-59	193	COG1414	DNA-binding transcriptional regulator, IclR family	246
2918743817	319	83.08	12	283	18	233	1.1e-24	81.8	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2918743818	545	97.2	23	410	2	383	2.8e-78	258.8	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2918743820	437	98.36	7	437	3	422	0.0e+00	583.5	COG3508	Homogentisate 1,2-dioxygenase	427
2918743821	325	97.18	5	324	8	317	6.0e-92	302.6	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918743822	424	88.28	51	424	30	270	6.6e-45	147.7	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
2918743823	655	97.63	3	621	10	626	0.0e+00	533	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
2918743824	173	94.61	7	165	2	159	6.3e-32	105.4	COG2891	Cell shape-determining protein MreD	167
2918743825	323	94.41	12	300	2	271	1.1e-61	202.9	COG1792	Cell shape-determining protein MreC	284
2918743826	347	98.24	5	347	2	336	0.0e+00	500.3	COG1077	Actin-like ATPase involved in cell morphogenesis	342
2918743827	99	98.96	1	99	1	95	9.0e-24	78.4	COG0721	Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit	96
2918743828	496	99.17	2	494	4	480	0.0e+00	555.2	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
2918743829	496	98.55	20	496	5	480	0.0e+00	648.9	COG0064	Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit	483
2918743831	227	99.01	10	224	3	203	1.4e-60	199	COG0461	Orotate phosphoribosyltransferase	201
2918743832	267	99.61	2	265	1	258	3.2e-78	257.2	COG0708	Exonuclease III	261
2918743835	661	18.73	341	472	210	271	1.8e-07	2	COG0790	TPR repeat	292
2918743835	661	66.47	391	615	25	244	1.8e-07	21.9	COG0790	TPR repeat	292
2918743836	254	89.66	17	241	15	222	2.7e-48	158.8	COG1802	DNA-binding transcriptional regulator, GntR family	230
2918743837	223	90.29	13	218	3	188	4.8e-41	135.3	COG1335	Nicotinamidase-related amidase	205
2918743838	531	99.4	17	521	4	501	0.0e+00	531.5	COG3845	ABC-type uncharacterized transport system, ATPase component	501
2918743839	234	96.6	23	234	2	200	6.9e-49	161	COG1335	Nicotinamidase-related amidase	205
2918743840	307	93.42	5	305	6	289	3.1e-75	247.3	COG1079	ABC-type uncharacterized transport system, permease component	304
2918743841	353	94.41	1	349	9	346	2.5e-88	290.6	COG4603	ABC-type uncharacterized transport system, permease component	356
2918743842	372	96.03	5	353	4	342	4.4e-73	240.8	COG1744	Basic membrane lipoprotein Med, periplasmic binding protein (PBP1-ABC) superfamily	345
2918743844	277	95.62	28	277	3	242	6.7e-65	213.7	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2918743846	276	94.96	21	276	11	255	2.6e-64	211.7	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2918743847	334	93.43	10	332	6	318	1.4e-35	117.3	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918743848	569	84.41	5	413	70	475	7.2e-97	319.7	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
2918743849	288	43.3	21	287	55	264	5.8e-34	112	COG4783	Putative Zn-dependent protease, contains TPR repeats	484
2918743850	461	50.91	263	460	8	202	4.2e-10	14.2	COG0477	MFS family permease	338
2918743850	461	58.22	30	296	4	226	4.2e-10	23.7	COG0477	MFS family permease	338
2918743851	398	98.07	6	398	7	412	1.3e-85	282.2	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
2918743853	568	84.77	5	398	3	347	7.0e-30	98.5	COG0644	Dehydrogenase (flavoprotein)	396
2918743854	237	99.14	4	236	2	231	4.3e-81	266.2	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918743855	399	79.19	73	399	79	390	5.0e-64	211.8	COG0642	Signal transduction histidine kinase	336
2918743856	419	86.71	6	406	42	413	6.9e-13	42.6	COG3307	O-antigen ligase	424
2918743857	140	16.27	2	129	492	600	2.0e-01	4.4	COG1269	Archaeal/vacuolar-type H+-ATPase subunit I/STV1	660
2918743858	69	59.68	10	61	25	61	3.1e-15	50.2	COG4391	Uncharacterized conserved protein, contains Zn-finger domain	62
2918743859	317	99.3	12	307	2	284	3.2e-93	307.3	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
2918743860	334	98.68	3	301	3	301	1.6e-84	278.2	COG2974	DNA recombination-dependent growth factor C	303
2918743862	462	99.56	1	461	1	454	0.0e+00	632.8	COG1066	Predicted ATP-dependent serine protease	456
2918743863	144	87.22	13	142	11	126	3.1e-18	60.6	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918743864	211	79.12	2	209	57	272	8.5e-26	85.5	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
2918743865	256	80.22	3	256	52	270	2.0e-77	255	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
2918743866	330	98.12	8	329	5	317	1.2e-85	282	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918743867	488	99.16	4	480	2	476	0.0e+00	584.5	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918743868	324	98.43	1	322	5	318	4.9e-93	306.4	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918743869	287	99.26	5	282	2	268	4.4e-75	247.2	COG3384	Aromatic ring-opening dioxygenase, catalytic subunit, LigB family	268
2918743870	134	99.21	1	134	1	126	7.0e-28	92	COG3232	5-carboxymethyl-2-hydroxymuconate isomerase	127
2918743871	267	98.48	1	267	1	260	2.8e-110	362.3	COG3971	2-keto-4-pentenoate hydratase	264
2918743872	273	99.22	1	263	2	254	4.7e-106	348.3	COG3836	2-keto-3-deoxy-L-rhamnonate aldolase RhmA	255
2918743873	576	98.1	1	569	8	574	0.0e+00	598.2	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
2918743874	329	97.81	5	327	6	317	1.2e-72	239.3	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918743875	265	90.62	19	242	3	205	8.9e-45	147.5	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
2918743876	325	99.03	1	325	1	306	8.0e-74	241.6	COG1893	Ketopantoate reductase	307
2918743879	366	98.35	1	362	2	359	2.0e-109	360.3	COG0787	Alanine racemase	360
2918743880	434	95.56	2	411	3	368	8.1e-14	46	COG0477	MFS family permease	338
2918743881	296	95.35	1	289	10	296	4.1e-27	89.8	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918743882	163	98.77	1	162	2	161	3.6e-73	238.8	COG0386	Glutathione peroxidase, house-cleaning role in reducing lipid peroxides	162
2918743884	410	99.25	15	410	3	400	1.5e-80	265.6	COG0247	Fe-S oxidoreductase	388
2918743885	369	36.25	183	369	297	466	7.5e-41	3	COG0277	FAD/FMN-containing dehydrogenase	459
2918743885	369	37.31	4	195	43	217	7.5e-41	135.2	COG0277	FAD/FMN-containing dehydrogenase	459
2918743886	500	98.72	20	476	6	468	2.8e-117	386.9	COG0277	FAD/FMN-containing dehydrogenase	459
2918743887	293	97.34	7	293	2	294	9.4e-53	174.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918743888	312	92.23	5	310	24	308	1.1e-62	204.6	COG3386	Sugar lactone lactonase YvrE	307
2918743889	511	98.3	72	511	2	406	0.0e+00	504.9	COG0004	Ammonia channel protein AmtB	409
2918743890	112	100	1	112	1	112	4.3e-49	160.3	COG0347	Nitrogen regulatory protein PII	112
2918743892	516	98.98	15	516	1	487	0.0e+00	603.3	COG0606	Predicted ATPase with chaperone activity	490
2918743893	721	63.83	13	387	3	302	2.6e-34	113.7	COG0515	Serine/threonine protein kinase	384
2918743894	241	58.59	12	174	5	137	6.1e-26	85.8	COG3913	Uncharacterized protein	227
2918743895	1211	99.58	1	1210	2	1187	0.0e+00	1070.3	COG3523	Type VI protein secretion system component VasK	1188
2918743896	459	87.5	26	288	30	260	6.3e-77	253.4	COG3455	Type VI protein secretion system component VasF	262
2918743897	458	99.1	17	458	4	445	0.0e+00	483.8	COG3522	Predicted component of the type VI protein secretion system	446
2918743898	171	87.58	1	163	7	147	3.0e-31	102.9	COG3521	Predicted component of the type VI protein secretion system	159
2918743900	634	48.38	13	260	23	231	1.2e-53	41.4	COG3456	Predicted component of the type VI protein secretion system, contains a FHA domain	430
2918743900	634	73.84	249	631	111	429	1.2e-53	141.5	COG3456	Predicted component of the type VI protein secretion system, contains a FHA domain	430
2918743901	273	87.5	10	254	20	257	7.3e-36	118.2	COG0631	Serine/threonine protein phosphatase PrpC	262
2918743904	349	52.99	5	153	104	236	1.5e-67	87.3	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2918743904	349	54.18	111	245	50	185	1.5e-67	68.9	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2918743904	349	66.14	157	345	35	200	1.5e-67	93	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2918743905	868	60.96	490	693	44	196	1.1e-51	86.6	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2918743905	868	67.3	35	303	71	317	4.4e-26	85.8	COG5351	Uncharacterized protein	367
2918743905	868	71.71	660	865	58	237	1.1e-51	89.8	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2918743907	797	95.67	1	610	9	561	0.0e+00	578.4	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
2918743908	909	98.63	12	908	2	795	0.0e+00	934.9	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
2918743909	382	94.63	29	362	16	332	1.0e-98	325.2	COG3520	Predicted component of the type VI protein secretion system	335
2918743910	623	99.84	1	623	1	620	0.0e+00	695.4	COG3519	Type VI protein secretion system component VasA	621
2918743911	186	93.63	22	182	5	151	6.4e-34	111.2	COG3518	Predicted component of the type VI protein secretion system	157
2918743912	288	94.87	5	287	11	269	4.5e-60	189.7	COG4455	Protein of avirulence locus involved in temperature-dependent protein secretion	273
2918743913	160	96.2	1	160	1	152	2.8e-27	90.2	COG3157	Type VI protein secretion system component Hcp (secreted cytotoxin)	162
2918743914	502	98.59	1	499	7	494	0.0e+00	762.4	COG3517	Predicted component of the type VI protein secretion system	495
2918743915	190	96.45	6	173	2	164	2.4e-65	213.7	COG3516	Predicted component of the type VI protein secretion system	169
2918743916	363	97.17	6	357	6	348	2.0e-30	99.7	COG3515	Predicted component of the type VI protein secretion system	346
2918743917	395	99.21	5	395	4	379	0.0e+00	547.8	COG3970	Fumarylacetoacetate (FAA) hydrolase family protein	379
2918743918	1250	16.64	36	192	457	580	1.6e-86	50.6	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
2918743918	1250	31.71	786	900	41	92	2.1e-36	15.1	COG2010	Cytochrome c, mono- and diheme variants	150
2918743918	1250	70.12	1109	1247	46	160	2.1e-36	41	COG2010	Cytochrome c, mono- and diheme variants	150
2918743918	1250	75.57	177	775	182	744	1.6e-86	229.6	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
2918743918	1250	99.39	938	1111	1	163	2.1e-36	81.2	COG2010	Cytochrome c, mono- and diheme variants	150
2918743919	167	96.79	9	164	4	154	2.0e-56	184.4	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
2918743920	386	92.08	17	383	11	347	1.6e-44	147	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918743921	240	94.17	33	239	5	198	7.4e-54	177.1	COG1335	Nicotinamidase-related amidase	205
2918743922	244	99.16	5	244	2	236	1.4e-85	280.8	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2918743923	267	98.43	1	245	4	253	1.1e-83	275	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2918743924	641	90.09	2	306	29	319	2.7e-102	96.4	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918743924	641	96.28	318	622	9	319	2.7e-102	246.8	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918743925	401	90.44	9	386	28	358	1.1e-53	177	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918743928	302	88.28	2	266	11	236	1.8e-41	136.2	COG2122	Uncharacterized protein, UPF0280 family, ApbE superfamily	256
2918743930	257	98.88	1	254	4	268	1.0e-58	193.5	COG1018	Ferredoxin-NADP reductase	266
2918743931	256	75.6	3	230	8	165	8.7e-22	73.2	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918743932	399	12.53	8	90	27	77	2.9e-16	36.7	COG1228	Imidazolonepropionase or related amidohydrolase	406
2918743932	399	17.2	177	378	309	378	2.9e-16	17.3	COG1228	Imidazolonepropionase or related amidohydrolase	406
2918743933	134	92.09	1	133	10	137	1.8e-18	61.3	COG2246	Putative flippase GtrA (transmembrane translocase of bactoprenol-linked glucose)	139
2918743934	325	48.19	13	246	4	176	2.9e-14	48.6	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
2918743936	915	98.95	2	885	10	857	0.0e+00	1261.6	COG1410	Methionine synthase I, cobalamin-binding domain	842
2918743938	153	94.63	1	145	6	146	2.8e-52	171.2	COG4125	Uncharacterized membrane protein	149
2918743939	308	96.68	3	300	4	294	4.7e-48	159.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918743940	255	87.42	1	156	12	150	3.4e-30	99.3	COG4991	Uncharacterized conserved protein YraI	155
2918743941	348	98.08	6	332	6	311	7.1e-122	401	COG0646	Methionine synthase I (cobalamin-dependent), methyltransferase domain	311
2918743942	271	95.59	3	271	8	267	5.8e-94	308.9	COG3741	N-formylglutamate amidohydrolase	272
2918743943	460	88.44	1	452	49	423	2.1e-80	265	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
2918743944	416	98.03	8	416	4	402	1.1e-122	404.4	COG1228	Imidazolonepropionase or related amidohydrolase	406
2918743945	190	70.62	1	184	11	147	6.0e-49	161.2	COG3758	Various environmental stresses-induced protein Ves (function unknown)	193
2918743946	222	92.98	2	219	15	226	4.2e-78	256.6	COG0765	ABC-type amino acid transport system, permease component	222
2918743947	250	92.93	1	250	10	272	3.0e-60	198.6	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918743948	244	97.97	10	244	4	244	2.0e-51	168.8	COG1414	DNA-binding transcriptional regulator, IclR family	246
2918743949	323	96.24	2	321	10	316	2.6e-89	293.9	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918743950	268	68.11	33	259	85	289	2.1e-15	51	COG3221	ABC-type phosphate/phosphonate transport system, periplasmic component	299
2918743951	339	98.79	10	339	4	329	5.1e-87	286.7	COG2423	Ornithine cyclodeaminase/archaeal alanine dehydrogenase, mu-crystallin family	330
2918743952	574	98.4	11	574	5	556	0.0e+00	988	COG2987	Urocanate hydratase	561
2918743953	517	99	8	507	2	494	0.0e+00	668	COG2986	Histidine ammonia-lyase	498
2918743954	245	96.65	2	236	8	238	9.2e-68	222.8	COG2188	DNA-binding transcriptional regulator, GntR family	236
2918743955	262	98.01	4	260	3	248	5.7e-97	318.6	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2918743956	292	96.12	38	292	7	254	2.1e-69	228.3	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2918743957	322	93.73	2	322	10	323	7.4e-47	154.8	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918743958	633	98.17	9	633	7	597	0.0e+00	734.4	COG0514	Superfamily II DNA helicase RecQ	590
2918743959	396	98.72	45	387	3	311	9.1e-66	216.3	COG1957	Inosine-uridine nucleoside N-ribohydrolase	311
2918743960	540	61.27	141	430	77	326	4.0e-25	81.5	COG0793	C-terminal processing protease CtpA/Prc, contains a PDZ domain	406
2918743961	775	27.98	544	744	295	442	3.6e-48	105.2	COG0464	AAA+-type ATPase, SpoVK/Ycf46/Vps4 family	494
2918743961	775	35.35	283	544	296	482	3.6e-48	51.7	COG0464	AAA+-type ATPase, SpoVK/Ycf46/Vps4 family	494
2918743962	401	96.53	1	335	8	341	1.5e-112	371	COG1171	Threonine dehydratase	347
2918743964	620	98.52	4	620	9	607	0.0e+00	951.1	COG1274	Phosphoenolpyruvate carboxykinase, GTP-dependent	608
2918743965	182	32.23	7	179	39	165	6.6e-03	10.9	COG0642	Signal transduction histidine kinase	336
2918743966	326	99	8	317	1	298	1.9e-47	157	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918743968	271	12.79	201	251	111	132	1.8e-06	3.7	COG0622	Predicted phosphodiesterase	172
2918743968	271	39.53	3	114	2	69	1.8e-06	16.5	COG0622	Predicted phosphodiesterase	172
2918743969	527	81.86	30	520	58	454	3.6e-82	271	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
2918743970	409	28.64	237	309	7	65	4.1e-79	4.4	COG2715	Spore maturation protein SpmA (function unknown)	206
2918743970	409	98.54	1	215	2	204	4.1e-79	259.6	COG2715	Spore maturation protein SpmA (function unknown)	206
2918743971	670	98.17	4	657	12	654	0.0e+00	992.1	COG2015	Alkyl sulfatase BDS1 and related hydrolases, metallo-beta-lactamase superfamily	655
2918743972	303	97.34	1	299	1	293	7.8e-41	135.3	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918743973	169	83.24	5	168	10	163	1.4e-39	130.2	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
2918743975	299	96.35	5	299	8	297	4.8e-42	138.8	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918743976	312	99.68	1	312	2	309	2.9e-114	375.7	COG2066	Glutaminase	309
2918743977	330	97.51	1	322	3	315	8.1e-38	125.2	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2918743978	311	97.34	5	294	4	296	2.6e-54	179.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918743980	397	98.36	23	387	4	363	2.0e-66	219	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918743981	300	98.67	2	300	3	299	4.3e-92	303.4	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2918743982	350	96.9	7	343	8	320	3.6e-72	237.9	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918743983	266	96.88	15	266	6	253	1.3e-106	350.3	COG4674	ABC-type uncharacterized transport system, ATPase component	249
2918743984	229	96.2	1	229	3	230	4.8e-83	272.6	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2918743985	345	89.21	23	279	14	261	2.3e-44	145.8	COG0388	Predicted amidohydrolase	274
2918743986	437	93.75	3	436	10	429	2.0e-47	156.2	COG1457	Purine-cytosine permease or related protein	442
2918743987	336	90.05	1	333	17	351	2.1e-65	215.7	COG2021	Homoserine acetyltransferase	368
2918743988	275	68.79	2	268	27	253	1.5e-37	124	COG0714	MoxR-like ATPase	329
2918743990	384	95.36	1	359	7	355	2.3e-54	179.4	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918743991	215	95.88	13	205	7	192	1.8e-39	129.9	COG3707	Two-component response regulator, AmiR/NasT family, consists of REC and RNA-binding antiterminator (ANTAR) domains	194
2918743992	298	98.01	4	298	1	295	4.2e-60	198.7	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918743993	63	74.6	1	63	8	54	1.3e-09	31.1	COG5457	Uncharacterized conserved protein YjiS, DUF1127 family	63
2918743995	343	99.7	10	341	1	333	2.7e-109	360.1	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
2918743996	288	76.32	65	283	45	218	5.6e-37	121.9	COG3485	Protocatechuate 3,4-dioxygenase beta subunit	226
2918743997	254	99.25	7	253	2	267	9.0e-53	174.1	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918743998	295	99.33	1	293	2	297	1.0e-88	292.1	COG3246	Uncharacterized conserved protein, DUF849 family	298
2918743999	333	99.7	10	333	2	331	3.5e-58	192.1	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2918744001	332	98.43	11	330	3	316	2.4e-86	284.2	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918744002	557	99.44	21	544	3	534	9.1e-116	381.9	COG1574	Predicted amidohydrolase YtcJ	535
2918744003	193	94.06	1	188	12	201	6.4e-48	157.4	COG1573	Uracil-DNA glycosylase	202
2918744004	276	89.35	1	274	5	264	6.3e-71	233.4	COG2513	2-Methylisocitrate lyase and related enzymes, PEP mutase family	289
2918744005	152	91.93	1	151	6	153	6.5e-21	69.5	COG5615	Uncharacterized membrane protein	161
2918744006	146	97.95	13	140	2	144	5.2e-15	51.2	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2918744007	412	98.25	1	412	8	401	0.0e+00	489.7	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2918744008	399	98.5	10	398	3	395	2.0e-106	350.9	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918744009	302	98.67	6	302	2	298	1.5e-58	193.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918744010	134	93.33	5	122	2	113	4.9e-33	108.6	COG1950	Uncharacterized membrane protein YvlD, DUF360 family	120
2918744011	279	99.59	31	276	1	245	6.8e-73	239.2	COG1414	DNA-binding transcriptional regulator, IclR family	246
2918744012	358	83.13	10	292	3	278	2.3e-39	129.9	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
2918744013	222	89.83	23	203	12	170	1.4e-16	54.9	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
2918744014	430	97.63	50	430	7	376	7.7e-100	329.2	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
2918744015	346	81.63	1	279	6	276	6.5e-35	115.3	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
2918744016	459	99.58	1	459	1	479	6.9e-123	405.8	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
2918744017	261	95.45	15	261	9	260	1.1e-32	106.6	COG3971	2-keto-4-pentenoate hydratase	264
2918744018	237	98.31	2	237	5	236	6.6e-110	360.4	COG3826	Uncharacterized protein	236
2918744019	622	80.33	397	622	35	230	2.4e-47	155.2	COG2114	Adenylate cyclase, class 3	227
2918744020	671	98.91	70	640	1	546	0.0e+00	432.7	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
2918744021	242	95.22	2	231	7	205	2.0e-24	81.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918744022	314	82.39	1	308	2	277	4.6e-46	152.2	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918744023	260	97.21	5	260	3	246	4.9e-85	279.6	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2918744024	284	97.29	26	283	4	254	9.1e-53	173.7	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2918744025	264	94.96	4	264	11	255	1.1e-66	219.5	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2918744026	268	83.11	4	262	36	217	8.4e-27	88.4	COG1878	Kynurenine formamidase	218
2918744027	440	88.28	49	439	30	270	8.1e-46	150.9	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
2918744029	302	97.39	1	299	2	300	6.4e-41	134.8	COG0492	Thioredoxin reductase	305
2918744030	153	89.33	1	150	1	134	4.5e-28	92.6	COG1959	DNA-binding transcriptional regulator, IscR family	150
2918744032	146	88.68	1	146	16	156	6.1e-38	124.2	COG2030	Acyl dehydratase	159
2918744033	430	13.4	84	211	191	270	1.0e-53	5.9	COG0369	Sulfite reductase, alpha subunit (flavoprotein)	587
2918744033	430	37.19	201	430	376	597	1.0e-53	170.5	COG0369	Sulfite reductase, alpha subunit (flavoprotein)	587
2918744033	430	63.74	4	70	28	85	1.7e-10	34.4	COG1144	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit	91
2918744035	558	43.77	309	538	118	233	9.7e-36	23.6	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918744035	558	69.43	49	306	25	208	9.7e-36	97.7	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918744036	315	76.81	29	103	5	57	7.1e-05	16	COG1476	DNA-binding transcriptional regulator, XRE-family HTH domain	68
2918744036	315	91.28	141	312	2	158	2.9e-36	119.3	COG0703	Shikimate kinase	172
2918744038	516	98.33	5	510	3	473	2.8e-73	241.5	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918744039	515	97.46	1	515	5	542	1.1e-129	427.8	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
2918744040	268	90.51	7	263	22	288	1.8e-31	102.1	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918744041	390	94.26	11	379	8	352	5.1e-55	181.5	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918744042	290	97.34	2	290	4	296	7.6e-79	260	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2918744043	324	95.36	5	321	13	320	4.0e-74	244.3	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918744044	249	99.61	1	247	2	254	2.4e-82	270.6	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2918744045	233	99.16	1	233	3	237	3.8e-79	259.8	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2918744046	303	96.68	8	303	5	295	7.4e-67	220.8	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918744047	246	98.88	2	243	3	267	7.1e-61	200.6	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918744048	80	92.75	1	67	1	64	6.0e-23	74.9	COG1942	Phenylpyruvate tautomerase PptA, 4-oxalocrotonate tautomerase family	69
2918744049	643	99.67	1	639	2	611	0.0e+00	663.6	COG3284	Transcriptional regulator of acetoin/glycerol metabolism	606
2918744050	404	98.28	1	404	2	402	1.5e-39	130.8	COG1819	UDP:flavonoid glycosyltransferase YjiC, YdhE family	406
2918744051	214	95.69	4	209	5	204	2.9e-23	78.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918744052	600	63.97	6	116	17	103	5.7e-06	20.5	COG3631	Ketosteroid isomerase-related protein	133
2918744052	600	97.98	158	592	6	442	5.0e-104	343.3	COG2072	Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD	443
2918744053	236	95.87	12	228	7	215	6.7e-24	79	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2918744054	317	99.33	13	307	2	297	9.9e-64	209.8	COG3246	Uncharacterized conserved protein, DUF849 family	298
2918744055	330	97.18	4	328	8	317	5.3e-61	201	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918744056	313	80.55	3	306	4	268	1.8e-71	235.6	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
2918744057	605	85.74	33	586	13	499	1.4e-54	179.9	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2918744058	462	97.15	1	459	3	445	1.1e-99	328.9	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
2918744059	428	95	2	427	22	439	5.3e-126	415.1	COG1257	Hydroxymethylglutaryl-CoA reductase	436
2918744062	445	16.54	2	116	4	115	2.6e-04	14.2	COG2982	Uncharacterized protein involved in outer membrane biogenesis	648
2918744062	445	20.09	212	413	473	608	2.6e-04	1.1	COG2982	Uncharacterized protein involved in outer membrane biogenesis	648
2918744063	140	85.11	2	140	20	139	5.2e-38	124.7	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
2918744064	428	94.96	9	428	8	440	4.0e-116	382.6	COG2233	Xanthine/uracil permease	451
2918744065	258	98.69	12	258	1	226	7.4e-58	190.8	COG0850	Septum formation inhibitor MinC	219
2918744066	271	98.53	1	271	1	268	3.3e-130	427.7	COG2894	Septum formation inhibitor-activating ATPase MinD	272
2918744067	92	94.32	1	90	1	83	2.3e-31	102.2	COG0851	Septum formation topological specificity factor MinE	88
2918744068	305	93.9	30	305	13	289	1.4e-18	56.6	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918744070	200	92.34	1	200	9	201	3.3e-14	48.8	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918744071	314	98.34	1	299	1	296	1.3e-57	190.3	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918744073	147	95.42	4	146	6	130	6.7e-30	97.7	COG5455	Periplasmic regulator RcnB of Ni and Co efflux	129
2918744075	212	96.38	23	212	5	217	2.4e-25	80.6	COG2755	Lysophospholipase L1 or related esterase	216
2918744076	172	98.32	2	172	2	177	3.4e-27	90.1	COG1437	Adenylate cyclase class IV, CYTH domain (includes archaeal enzymes of unknown function)	178
2918744078	201	97.84	2	183	2	182	2.1e-61	201.3	COG2096	Cob(I)alamin adenosyltransferase	184
2918744080	474	97.65	22	474	10	467	1.7e-127	420.6	COG0277	FAD/FMN-containing dehydrogenase	459
2918744081	299	81.57	8	264	22	229	7.4e-05	15.3	COG1462	Curli biogenesis system outer membrane secretion channel CsgG	252
2918744082	315	90.91	40	304	12	251	5.7e-63	207.7	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
2918744083	181	96.13	2	181	4	177	2.3e-58	191.5	COG3545	Predicted esterase of the alpha/beta hydrolase fold	181
2918744084	304	98.11	1	261	1	259	1.0e-78	259.3	COG1192	Cellulose biosynthesis protein BcsQ	259
2918744085	204	97.6	2	204	4	206	1.7e-49	162.5	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
2918744086	213	97.67	5	213	4	213	4.2e-56	184.3	COG0357	16S rRNA G527 N7-methylase RsmG (former glucose-inhibited division protein B)	215
2918744087	652	99.52	3	635	2	622	0.0e+00	948	COG0445	tRNA U34 5-carboxymethylaminomethyl modifying enzyme MnmG/GidA	621
2918744088	61	92.59	1	54	1	50	7.1e-18	59.1	COG5487	Uncharacterized membrane protein YtjA, UPF0391 family	54
2918744089	202	98.6	1	200	1	212	9.8e-47	154.1	COG0625	Glutathione S-transferase	211
2918744090	367	98.07	1	367	3	358	3.6e-109	360	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
2918744091	173	79.41	8	160	23	130	1.7e-08	29	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
2918744092	480	84.26	98	468	56	387	6.2e-46	152.5	COG0642	Signal transduction histidine kinase	336
2918744093	229	99.14	1	229	1	230	6.7e-63	206.6	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918744094	292	92.59	13	273	16	240	1.9e-15	50.2	COG1647	Esterase/lipase	243
2918744095	99	93.83	7	95	3	78	4.0e-14	47.1	COG0236	Acyl carrier protein	80
2918744096	410	99.03	2	408	3	412	2.4e-100	330.8	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
2918744097	160	87.7	2	160	17	180	1.4e-19	65.4	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
2918744098	735	99.45	1	735	3	729	0.0e+00	839.9	COG2217	Cation transport ATPase	713
2918744099	64	89.04	1	64	5	69	1.0e-15	52.5	COG2608	Copper chaperone CopZ	71
2918744100	135	95.45	8	125	2	127	4.1e-34	112.3	COG0789	DNA-binding transcriptional regulator, MerR family	124
2918744101	316	43.75	7	115	77	139	8.4e-07	17.7	COG3793	Tellurite resistance protein	144
2918744101	316	78.42	149	294	4	112	3.2e-11	38	COG3597	Uncharacterized conserved protein, DUF697 family	139
2918744102	261	98.71	5	255	2	230	8.5e-73	238.9	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918744103	479	83.25	118	479	61	388	1.7e-60	200.4	COG0642	Signal transduction histidine kinase	336
2918744105	797	91.57	19	758	7	734	0.0e+00	891.8	COG5009	Membrane carboxypeptidase/penicillin-binding protein	797
2918744106	493	97.52	7	485	4	435	5.9e-108	355.6	COG4452	Inner membrane protein involved in colicin E2 resistance	443
2918744111	250	35.45	88	243	99	165	2.1e-08	28.5	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
2918744112	299	97.86	16	298	6	279	7.5e-93	305.5	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
2918744113	363	92.02	104	353	2	197	2.0e-25	84.2	COG0655	Multimeric flavodoxin WrbA	207
2918744116	260	97.67	9	260	5	255	2.0e-73	241.7	COG3568	Metal-dependent hydrolase, endonuclease/exonuclease/phosphatase family	259
2918744117	425	84.74	2	408	65	475	1.5e-77	255.8	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
2918744118	323	93.52	5	316	16	318	5.9e-52	171.5	COG0392	Uncharacterized membrane protein YbhN, UPF0104 family	322
2918744121	395	95.56	108	392	12	291	1.5e-50	166.2	COG1408	Predicted phosphohydrolase, MPP superfamily	284
2918744126	874	99.69	31	874	3	641	0.0e+00	910.7	COG0187	DNA gyrase/topoisomerase IV, subunit B	635
2918744127	368	98.36	3	368	6	364	1.4e-107	354.6	COG0592	DNA polymerase III sliding clamp (beta) subunit, PCNA homolog	364
2918744128	459	99.77	11	455	1	432	0.0e+00	549.9	COG0593	Chromosomal replication initiation ATPase DnaA	408
2918744129	44	100	1	44	1	44	2.8e-23	76.4	COG0230	Ribosomal protein L34	44
2918744130	139	88.98	1	132	5	109	7.9e-15	49.4	COG0594	RNase P protein component	117
2918744131	95	81.52	1	83	6	80	2.9e-33	108.1	COG0759	Membrane-anchored protein YidD, putatitve component of membrane protein insertase Oxa1/YidC/SpoIIIJ	92
2918744132	565	93.02	269	562	2	294	6.6e-94	309.4	COG0706	Membrane protein insertase Oxa1/YidC/SpoIIIJ, required for the localization of integral membrane proteins	314
2918744133	471	99.56	3	471	3	454	0.0e+00	506.4	COG0486	tRNA U34 5-carboxymethylaminomethyl modifying GTPase MnmE/TrmE	454
2918744134	154	50.92	14	153	21	131	2.0e-20	67.8	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2918744136	661	78.03	400	581	18	191	2.0e-26	88	COG1226	Voltage-gated potassium channel Kch	212
2918744136	661	96.5	1	400	10	395	4.2e-91	300.1	COG0475	Kef-type K+ transport system, membrane component KefB	397
2918744137	332	98.51	15	215	3	201	2.9e-77	253	COG0794	D-arabinose 5-phosphate isomerase GutQ	202
2918744138	182	94.71	10	178	5	165	2.3e-58	191.1	COG1778	 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsC and related HAD superfamily phosphatases	170
2918744139	211	92.51	1	205	8	180	3.3e-16	54.1	COG3117	Lipopolysaccharide export system protein LptC	188
2918744140	260	96.6	1	257	8	263	3.8e-51	168.4	COG0300	Short-chain dehydrogenase	265
2918744143	187	95.83	1	186	1	184	3.5e-62	203.9	COG2119	Putative Ca2+/H+ antiporter, TMEM165/GDT1 family	190
2918744144	386	95.7	1	375	15	370	0.0e+00	470.6	COG2021	Homoserine acetyltransferase	368
2918744145	195	45.19	3	151	41	148	4.9e-10	33.3	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
2918744146	196	95.05	1	194	5	196	8.4e-50	163.4	COG1739	Putative translation regulator, IMPACT (imprinted ancient) protein family	203
2918744147	310	13.9	30	74	29	59	7.4e-10	3.5	COG1226	Voltage-gated potassium channel Kch	212
2918744147	310	72.65	78	268	5	166	7.4e-10	33.9	COG1226	Voltage-gated potassium channel Kch	212
2918744148	154	55.48	33	152	42	122	8.0e-14	45.7	COG1664	Cytoskeletal protein CcmA, bactofilin family	146
2918744149	261	93.61	7	261	2	250	2.8e-65	215.2	COG1801	Uncharacterized conserved protein YecE, DUF72 family	263
2918744150	503	97.61	18	492	9	416	8.6e-36	118.4	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
2918744151	288	94.81	8	288	15	306	1.2e-60	199.7	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
2918744152	392	48.83	206	391	16	202	2.6e-15	23.8	COG0477	MFS family permease	338
2918744152	392	60.57	2	248	17	248	2.6e-15	27	COG0477	MFS family permease	338
2918744153	153	86	1	146	11	139	1.6e-35	117	COG3753	Uncharacterized conserved protein YidB, DUF937 family	143
2918744154	451	95.45	55	424	7	405	4.4e-39	129.2	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
2918744155	244	96.75	1	243	3	240	6.0e-66	216.7	COG1385	16S rRNA U1498 N3-methylase RsmE	246
2918744156	364	94.3	15	358	13	343	1.9e-110	363.6	COG3178	Predicted phosphotransferase, aminoglycoside/choline kinase (APH/ChoK) family	351
2918744157	860	94.47	16	851	35	786	2.1e-125	414.5	COG1452	LPS assembly outer membrane protein LptD (organic solvent tolerance protein OstA)	784
2918744158	469	50.77	309	468	156	320	1.7e-67	124.8	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
2918744158	469	73.54	50	314	28	266	1.7e-67	103.4	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
2918744159	256	96.54	3	255	5	255	7.2e-80	262.4	COG0030	16S rRNA A1518 and A1519 N6-dimethyltransferase RsmA/KsgA/DIM1 (may also have DNA glycosylase/AP lyase activity)	259
2918744161	159	74.73	65	151	14	81	1.4e-06	22.3	COG2732	Barstar, RNAse (barnase) inhibitor	91
2918744162	136	84.21	1	136	24	151	9.3e-47	153.7	COG4290	Guanyl-specific ribonuclease Sa	152
2918744163	780	96.83	7	446	13	440	0.0e+00	567.6	COG0281	Malic enzyme	432
2918744163	780	99.39	443	780	1	325	1.3e-106	350.2	COG0280	Phosphotransacetylase	327
2918744164	349	98.26	1	349	1	339	2.5e-97	320.4	COG4260	Membrane protease subunit, stomatin/prohibitin family, contains C-terminal Zn-ribbon domain	345
2918744165	493	24.59	210	237	21	35	4.6e-04	10.3	COG2888	Predicted RNA-binding protein involved in translation, contains  Zn-ribbon domain, DUF1610 family	61
2918744165	493	50.82	6	53	10	40	4.6e-04	8.5	COG2888	Predicted RNA-binding protein involved in translation, contains  Zn-ribbon domain, DUF1610 family	61
2918744166	72	41.35	7	72	77	131	5.0e-07	24.1	COG3766	Uncharacterized membrane protein YjfL, UPF0719 family	133
2918744167	514	98.43	9	508	8	507	0.0e+00	588.7	COG4262	Predicted spermidine synthase with an N-terminal membrane domain	508
2918744168	542	63.44	47	384	4	291	1.8e-16	51.6	COG1231	Monoamine oxidase	450
2918744169	454	97.57	19	441	11	412	0.0e+00	446.1	COG4222	Uncharacterized conserved protein	391
2918744170	324	97.01	5	301	5	296	3.8e-69	228.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918744171	464	95.9	16	459	16	389	9.5e-91	298.1	COG0006	Xaa-Pro aminopeptidase	384
2918744172	245	61.11	6	243	3	233	7.0e-41	134.4	COG1208	NDP-sugar pyrophosphorylase, includes eIF-2Bgamma, eIF-2Bepsilon, and LPS biosynthesis proteins	358
2918744173	126	80.29	1	126	15	124	1.3e-23	78.1	COG1586	S-adenosylmethionine decarboxylase or arginine decarboxylase	136
2918744174	701	99.25	1	700	5	662	0.0e+00	940.6	COG0021	Transketolase	663
2918744175	333	98.51	2	333	2	331	0.0e+00	480.6	COG0057	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase	335
2918744178	102	93.94	1	102	3	95	2.4e-21	70.2	COG1359	Quinol monooxygenase YgiN	100
2918744179	442	96.9	20	441	12	418	0.0e+00	466.3	COG1914	Mn2+ and Fe2+ transporters of the NRAMP family	416
2918744181	356	52.63	29	354	244	513	1.4e-98	326	COG3227	Zn-dependent metalloprotease	507
2918744182	96	89.13	1	91	3	84	6.7e-16	53.1	COG2350	Uncharacterized conserved protein YciI, contains a putative active-site phosphohistidine	92
2918744183	363	95	31	332	14	279	1.3e-69	229.3	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
2918744184	140	96.99	2	135	3	131	8.1e-55	179	COG3607	Predicted lactoylglutathione lyase	133
2918744185	457	22.04	334	455	363	468	9.8e-103	63	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
2918744185	457	66.53	7	342	5	324	9.8e-103	275.2	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
2918744186	534	87.5	2	501	3	394	4.6e-42	138.4	COG3025	Inorganic triphosphatase YgiF, contains CYTH and CHAD domains	432
2918744187	158	91.53	1	158	1	162	3.9e-44	144.9	COG1047	FKBP-type peptidyl-prolyl cis-trans isomerase 2	174
2918744188	312	98.34	2	299	1	296	1.2e-67	223.3	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918744189	285	86.07	6	274	5	245	6.4e-45	148.3	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
2918744190	263	95.09	13	233	3	215	8.9e-52	170.4	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
2918744191	522	95.16	1	521	21	570	5.0e-111	367	COG0747	ABC-type transport system, periplasmic component	556
2918744192	323	98.43	3	323	3	315	1.9e-112	370.3	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2918744193	283	94.63	2	281	14	295	1.1e-98	324.4	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2918744194	552	99.09	7	543	4	550	0.0e+00	659.4	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
2918744195	322	88.04	18	322	40	326	2.3e-69	228.2	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
2918744196	456	97.76	5	455	4	440	0.0e+00	517.2	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
2918744197	352	89.34	1	352	7	316	3.0e-82	271	COG0123	Acetoin utilization deacetylase AcuC or a related deacetylase	340
2918744198	308	96.35	14	300	7	296	1.5e-40	133.4	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918744199	242	91.38	10	235	12	223	1.0e-52	173.3	COG1802	DNA-binding transcriptional regulator, GntR family	230
2918744200	342	87.03	1	342	15	316	1.1e-83	275.7	COG0123	Acetoin utilization deacetylase AcuC or a related deacetylase	340
2918744201	351	95.22	8	348	5	323	1.0e-69	229.4	COG2334	Ser/Thr protein kinase RdoA involved in Cpx stress response, MazF antagonist	331
2918744202	427	96.19	1	427	15	443	0.0e+00	461.3	COG0160	4-aminobutyrate aminotransferase or related aminotransferase	447
2918744203	401	98.22	1	399	5	390	6.1e-129	425.1	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
2918744204	324	97.18	5	322	7	316	2.8e-78	257.7	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918744205	304	97.32	2	300	4	294	2.7e-83	273.7	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
2918744206	380	95.63	17	379	6	355	1.9e-75	248.7	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918744207	312	96.77	1	312	5	334	6.5e-101	332.3	COG3938	Proline racemase	341
2918744208	376	96.91	1	371	4	379	5.2e-67	221.3	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918744209	82	24.36	2	82	39	76	5.1e-06	20.3	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
2918744210	430	11.63	2	70	146	195	1.0e-34	36.3	COG0446	NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase	415
2918744210	430	80.47	51	420	64	409	1.0e-34	84	COG0446	NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase	415
2918744211	222	90.95	1	222	7	217	2.0e-39	130.1	COG1802	DNA-binding transcriptional regulator, GntR family	230
2918744212	307	86.17	1	305	18	316	2.1e-48	159.7	COG3239	Fatty acid desaturase	343
2918744215	476	73.85	4	455	29	412	0.0e+00	438.6	COG0513	Superfamily II DNA and RNA helicase	513
2918744216	90	96	1	74	1	72	1.5e-28	92.6	COG0361	Translation initiation factor IF-1	75
2918744218	351	99.28	7	325	3	278	5.2e-50	164.9	COG1082	Sugar phosphate isomerase/epimerase	274
2918744219	283	83.2	4	264	19	221	1.3e-53	176.4	COG2071	Gamma-glutamyl-gamma-aminobutyrate hydrolase PuuD (putrescine degradation), contains GATase1-like domain	243
2918744220	60	8.13	1	55	3	38	7.3e-03	10.6	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
2918744221	290	94.85	7	288	7	264	2.8e-63	208	COG3741	N-formylglutamate amidohydrolase	272
2918744222	321	96.87	1	319	4	312	3.6e-87	287.1	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918744223	308	98.34	8	302	2	297	3.6e-61	202.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918744224	331	96.87	6	329	8	316	9.3e-80	262.5	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918744225	982	20	755	778	7	19	1.1e-02	5.1	COG3024	Endogenous inhibitor of DNA gyrase, YacG/DUF329 family	65
2918744225	982	21.54	644	668	6	19	1.1e-02	3.5	COG3024	Endogenous inhibitor of DNA gyrase, YacG/DUF329 family	65
2918744225	982	98.43	2	647	1	566	0.0e+00	476.1	COG0550	DNA topoisomerase IA	570
2918744227	275	98.74	29	271	2	237	5.2e-48	158.4	COG0340	Biotin-(acetyl-CoA carboxylase) ligase	238
2918744229	481	81.98	119	479	63	385	8.8e-57	188.2	COG0642	Signal transduction histidine kinase	336
2918744230	223	99.14	1	222	1	230	5.8e-73	239.5	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918744231	161	69.17	26	146	15	106	3.5e-13	44.2	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918744232	372	98.97	11	294	2	289	1.1e-129	426	COG0468	RecA/RadA recombinase	279
2918744233	150	84.3	5	150	21	165	6.0e-38	124.9	COG2137	SOS response regulatory protein OraA/RecX, interacts with RecA	174
2918744234	307	95.7	1	307	2	335	8.3e-73	236.1	COG0002	N-acetyl-gamma-glutamylphosphate reductase	349
2918744235	388	99.74	1	388	1	382	0.0e+00	520.6	COG0045	Succinyl-CoA synthetase, beta subunit	387
2918744236	297	97.96	1	297	1	288	1.7e-118	389.7	COG0074	Succinyl-CoA synthetase, alpha subunit	293
2918744237	228	93.36	1	227	8	246	5.8e-46	150.1	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
2918744238	266	94.12	10	264	5	260	2.3e-63	208.6	COG0631	Serine/threonine protein phosphatase PrpC	262
2918744240	753	24.88	2	119	17	117	6.7e-47	65.6	COG4252	Extracellular (periplasmic) sensor domain CHASE2 (specificity unknown)	400
2918744240	753	40.15	246	455	230	392	6.7e-47	94.1	COG4252	Extracellular (periplasmic) sensor domain CHASE2 (specificity unknown)	400
2918744240	753	91.8	437	681	10	233	1.6e-51	168.9	COG2114	Adenylate cyclase, class 3	227
2918744241	267	82.84	1	242	2	252	2.0e-18	53.2	COG1234	Ribonuclease BN, tRNA processing enzyme	292
2918744242	162	97.44	5	146	3	154	3.3e-19	64.2	COG2165	Type II secretory pathway, pseudopilin PulG	149
2918744244	143	90.2	4	141	14	151	3.8e-30	99.4	COG1963	Acid phosphatase family membrane protein YuiD	153
2918744245	281	95.17	1	276	12	287	5.5e-37	121.7	COG0382	4-hydroxybenzoate polyprenyltransferase	289
2918744246	151	92.81	11	151	9	137	6.3e-07	22.9	COG2246	Putative flippase GtrA (transmembrane translocase of bactoprenol-linked glucose)	139
2918744247	430	83.37	24	418	56	446	1.5e-37	124	COG0277	FAD/FMN-containing dehydrogenase	459
2918744248	190	59.62	2	189	97	254	9.0e-23	75.4	COG0300	Short-chain dehydrogenase	265
2918744253	1214	85.84	241	1211	77	979	1.2e-116	385.9	COG3419	Tfp pilus assembly protein, tip-associated adhesin PilY1	1036
2918744254	228	84.24	2	154	4	142	3.9e-10	34	COG4967	Tfp pilus assembly protein PilV	162
2918744255	392	22.09	238	389	200	271	1.2e-12	8.4	COG4966	Tfp pilus assembly protein PilW	318
2918744255	392	33.44	9	213	8	116	1.2e-12	36.1	COG4966	Tfp pilus assembly protein PilW	318
2918744256	126	46.67	1	121	13	89	3.7e-13	43.7	COG4967	Tfp pilus assembly protein PilV	162
2918744257	207	94.02	3	198	6	178	1.7e-24	81.4	COG4970	Tfp pilus assembly protein FimT	181
2918744258	163	97.12	12	156	5	139	3.9e-27	89.9	COG4968	Tfp pilus assembly protein PilE	139
2918744259	576	64.1	120	426	139	413	3.7e-14	47.2	COG3307	O-antigen ligase	424
2918744260	163	98.08	1	160	2	154	1.9e-63	207.6	COG0315	Molybdenum cofactor biosynthesis enzyme	157
2918744261	487	90.93	2	481	33	473	3.9e-85	281	COG4783	Putative Zn-dependent protease, contains TPR repeats	484
2918744262	117	93.33	1	116	2	113	1.2e-33	110.6	COG1950	Uncharacterized membrane protein YvlD, DUF360 family	120
2918744264	244	92.97	1	240	13	250	8.8e-49	159.8	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
2918744265	154	82.43	67	140	6	66	1.7e-16	54.4	COG3313	Predicted Fe-S protein YdhL, DUF1289 family	74
2918744267	186	98.34	1	186	1	178	5.0e-60	196.7	COG4681	Uncharacterized conserved protein YaeQ, suppresses RfaH defect	181
2918744268	723	94.56	4	723	42	754	0.0e+00	618.7	COG4772	Outer membrane receptor for Fe3+-dicitrate	753
2918744269	380	22.12	265	379	295	392	5.8e-50	54.7	COG3182	Uncharacterized iron-regulated membrane protein	442
2918744269	380	59.37	2	279	3	265	5.8e-50	115.7	COG3182	Uncharacterized iron-regulated membrane protein	442
2918744270	459	99.32	12	459	1	436	1.0e-126	417.9	COG0015	Adenylosuccinate lyase	438
2918744271	203	93.95	1	203	1	202	5.5e-44	145.2	COG0625	Glutathione S-transferase	211
2918744272	205	90.74	47	203	12	158	2.0e-55	181	COG0386	Glutathione peroxidase, house-cleaning role in reducing lipid peroxides	162
2918744273	285	42.72	55	116	44	87	3.2e-07	11.5	COG3461	Uncharacterized protein	103
2918744273	285	52.43	115	194	29	82	3.2e-07	12.5	COG3461	Uncharacterized protein	103
2918744274	293	85.48	2	171	20	178	6.5e-33	108.5	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918744275	155	73.66	5	150	48	184	1.7e-35	117.3	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
2918744276	376	62.5	5	263	63	217	2.5e-61	202.2	COG0797	Rare lipoprotein A, peptidoglycan hydrolase digesting "naked" glycans, contains C-terminal SPOR domain	233
2918744277	919	93.98	2	919	50	954	0.0e+00	825.8	COG1391	Glutamine synthetase adenylyltransferase	963
2918744278	1350	97.17	1	1334	30	1264	0.0e+00	682.6	COG3164	Uncharacterized conserved protein YhdP, contains DUF3971 and AsmA2 domains	1271
2918744279	271	94.24	1	269	3	264	1.0e-74	245.6	COG0388	Predicted amidohydrolase	274
2918744280	678	8.94	16	81	6	59	1.8e-50	5.9	COG4191	Signal transduction histidine kinase regulating C4-dicarboxylate transport system	603
2918744280	678	58.11	200	678	251	601	1.8e-50	166	COG4191	Signal transduction histidine kinase regulating C4-dicarboxylate transport system	603
2918744281	208	94.06	5	208	6	195	1.2e-62	205.5	COG4566	Two-component response regulator, FixJ family, consists of REC and HTH domains	202
2918744282	187	86.93	2	186	24	196	5.3e-39	129.1	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
2918744283	219	88.44	16	215	21	196	2.1e-44	146.8	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
2918744285	382	69.13	72	382	114	375	1.0e-77	256.2	COG2821	Membrane-bound lytic murein transglycosylase	373
2918744286	750	99.36	16	750	4	622	0.0e+00	550.9	COG3211	Secreted phosphatase, PhoX family	616
2918744287	154	96.84	1	152	5	157	1.0e-42	140.5	COG1522	DNA-binding transcriptional regulator, Lrp family	154
2918744288	888	96.17	15	887	5	857	0.0e+00	1190.6	COG2609	Pyruvate dehydrogenase complex, dehydrogenase (E1) component	887
2918744289	153	26.23	4	116	119	198	3.0e-05	18.2	COG0053	Divalent metal cation (Fe/Co/Zn/Cd) transporter	304
2918744290	258	94.61	6	238	8	235	6.8e-64	209.9	COG2186	DNA-binding transcriptional regulator, FadR family	241
2918744291	440	48.83	252	439	4	190	1.9e-30	19.9	COG0477	MFS family permease	338
2918744291	440	53.79	25	253	6	211	1.9e-30	87.3	COG0477	MFS family permease	338
2918744292	308	98.95	8	296	3	285	5.4e-90	296	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
2918744293	297	98.31	4	296	5	294	1.8e-38	127.4	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918744294	337	97.2	1	329	2	313	1.7e-42	140.6	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2918744295	423	98.8	4	423	3	412	2.1e-130	429.8	COG3395	Uncharacterized conserved protein YgbK, DUF1537 family	413
2918744296	222	88.39	1	222	3	200	2.1e-41	136.6	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
2918744297	272	99.23	1	271	1	258	1.6e-108	356.8	COG3622	Hydroxypyruvate isomerase	260
2918744298	399	88.68	11	398	25	400	5.7e-36	118.4	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
2918744299	155	89.71	2	151	14	135	1.0e-17	55.2	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
2918744300	217	81.34	27	214	20	189	5.9e-18	60.8	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918744301	319	98.51	3	260	4	267	6.0e-64	210.5	COG1018	Ferredoxin-NADP reductase	266
2918744302	196	98.43	1	196	1	188	1.1e-35	117.9	COG2249	Putative NADPH-quinone reductase (modulator of drug activity B)	189
2918744303	328	92.24	1	320	19	327	7.2e-33	108.8	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918744304	459	3.62	421	451	449	465	1.0e-39	3.3	COG0277	FAD/FMN-containing dehydrogenase	459
2918744304	459	46.91	14	364	6	225	1.0e-39	127.1	COG0277	FAD/FMN-containing dehydrogenase	459
2918744305	293	97.29	29	289	6	256	1.1e-61	203.1	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2918744306	266	96.81	9	261	3	245	5.0e-85	279.6	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2918744307	273	97.59	9	264	5	247	2.5e-70	231.3	COG1402	 Creatinine amidohydrolase/Fe(II)-dependent formamide hydrolase involved in riboflavin and F420 biosynthesis	250
2918744309	385	93.31	1	282	3	239	3.4e-59	194.4	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
2918744310	598	91.92	20	583	7	529	0.0e+00	672.7	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
2918744311	204	84.98	5	194	29	209	3.4e-34	112.5	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
2918744312	233	93.9	13	233	11	210	1.2e-62	205.6	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
2918744313	104	86.96	2	104	13	112	1.9e-54	177.2	COG5605	Cytochrome c oxidase subunit IV	115
2918744314	542	50.39	232	464	13	205	9.7e-21	19.7	COG0477	MFS family permease	338
2918744314	542	53.79	26	253	4	209	9.7e-21	54.7	COG0477	MFS family permease	338
2918744315	256	92.54	6	254	17	227	4.0e-79	259.9	COG0765	ABC-type amino acid transport system, permease component	222
2918744316	252	93.99	1	251	9	274	4.7e-59	194.6	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918744317	158	94.94	1	153	3	152	1.3e-37	123.9	COG1522	DNA-binding transcriptional regulator, Lrp family	154
2918744318	1198	93.14	760	967	5	194	1.5e-28	93.5	COG1014	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, gamma subunit	203
2918744318	1198	98.91	26	740	3	639	0.0e+00	591.8	COG4231	TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit	640
2918744319	111	90.72	16	111	7	94	2.3e-31	102.4	COG1862	Preprotein translocase subunit YajC	97
2918744320	627	99.62	75	610	3	523	0.0e+00	586.9	COG0342	Preprotein translocase subunit SecD	506
2918744321	319	96.75	1	305	2	299	3.3e-106	349.4	COG0341	Preprotein translocase subunit SecF	305
2918744323	172	89.81	1	172	1	141	4.1e-34	104.8	COG2922	Uncharacterized conserved protein Smg, DUF494 family	157
2918744324	386	98.89	1	383	4	358	1.3e-111	367.7	COG0758	Predicted Rossmann fold nucleotide-binding protein DprA/Smf involved in DNA uptake	350
2918744326	173	99.41	1	165	1	168	1.9e-62	204.3	COG0242	Peptide deformylase	168
2918744328	318	99.35	3	315	2	307	5.6e-105	345.6	COG0223	Methionyl-tRNA formyltransferase	307
2918744329	246	91.63	3	240	8	226	3.5e-46	152.1	COG1296	Predicted branched-chain amino acid permease (azaleucine resistance)	238
2918744330	111	92.52	4	109	6	104	2.7e-22	73.8	COG4392	Branched-chain amino acid transport protein	107
2918744331	324	97.81	1	323	6	317	1.3e-86	285.3	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918744332	323	78.08	11	296	18	220	2.6e-25	84	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2918744334	550	97.2	30	417	3	384	3.8e-65	215	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2918744335	373	69.49	86	373	87	291	8.2e-07	23.3	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918744336	182	99.32	12	144	2	146	2.0e-16	56	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2918744337	301	98.01	3	300	2	296	2.5e-66	219	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918744338	397	97.74	4	396	8	396	0.0e+00	482	COG0126	3-phosphoglycerate kinase	395
2918744339	482	98.54	6	481	5	475	0.0e+00	583.1	COG0469	Pyruvate kinase	477
2918744340	338	99.38	1	335	1	321	5.5e-127	417.9	COG2515	1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase, PLP-dependent ACC family	323
2918744341	169	97.47	15	169	3	156	2.8e-36	119.6	COG1522	DNA-binding transcriptional regulator, Lrp family	154
2918744342	354	99.65	1	329	1	287	4.5e-110	362	COG0191	Fructose/tagatose bisphosphate aldolase	286
2918744343	301	99.27	6	301	3	275	8.5e-94	308.3	COG0152	Phosphoribosylaminoimidazole-succinocarboxamide synthase	247
2918744344	150	94.48	10	149	5	141	8.8e-24	78.5	COG3187	Heat shock protein HslJ	142
2918744345	306	91.15	1	305	26	303	1.8e-72	238.1	COG3118	Negative regulator of GroEL, contains thioredoxin-like and TPR-like domains	304
2918744346	181	92.07	1	161	4	154	4.1e-70	229.1	COG0041	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase	162
2918744347	396	96.54	11	387	2	364	8.9e-129	424.1	COG0026	Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)	375
2918744348	333	94.34	2	214	11	210	3.3e-68	223	COG0009	tRNA A37 threonylcarbamoyladenosine synthetase subunit TsaC/SUA5/YrdC	211
2918744349	527	84.07	87	478	21	268	1.5e-06	22.5	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918744350	477	98.95	1	477	1	471	1.7e-99	328.4	COG2027	D-alanyl-D-alanine carboxypeptidase	470
2918744351	196	86.05	33	193	10	157	1.0e-11	39.5	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2918744352	254	96.85	1	252	1	246	3.2e-69	228	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
2918744353	338	95.02	7	321	7	292	7.4e-29	95.4	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918744354	238	98.19	2	219	3	219	4.5e-50	165.2	COG1214	tRNA A37 threonylcarbamoyladenosine modification protein TsaB	220
2918744355	180	90.48	1	171	16	186	6.8e-24	79.3	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
2918744356	264	76.24	108	261	43	196	2.4e-21	69.8	COG1573	Uracil-DNA glycosylase	202
2918744357	273	98.75	2	270	2	238	1.2e-48	160.1	COG0284	Orotidine-5'-phosphate decarboxylase	240
2918744358	244	75.34	9	73	15	69	5.3e-05	16.8	COG3655	DNA-binding transcriptional regulator, XRE family	73
2918744360	653	76.25	414	647	11	209	6.2e-44	144.1	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
2918744361	165	70.83	3	79	6	73	1.3e-23	38.1	COG4298	Uncharacterized protein	95
2918744361	165	76.04	74	163	12	84	1.3e-23	39.3	COG4298	Uncharacterized protein	95
2918744362	152	23.33	28	141	4	97	1.7e-02	8.9	COG3391	DNA-binding beta-propeller fold protein YncE	381
2918744363	265	88.5	1	263	6	259	7.4e-64	210.1	COG4727	Uncharacterized protein	287
2918744364	373	78.69	285	343	10	57	1.4e-02	9.5	COG2888	Predicted RNA-binding protein involved in translation, contains  Zn-ribbon domain, DUF1610 family	61
2918744366	261	99.25	16	261	2	267	2.4e-57	189.2	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918744368	405	15.59	343	405	306	363	0.0e+00	59.9	COG0343	Queuine/archaeosine tRNA-ribosyltransferase	372
2918744368	405	81.18	14	330	5	306	0.0e+00	460.1	COG0343	Queuine/archaeosine tRNA-ribosyltransferase	372
2918744369	417	68.52	59	411	124	406	7.7e-34	111.7	COG2133	Glucose/arabinose dehydrogenase, beta-propeller fold	399
2918744370	347	98.85	4	346	2	346	0.0e+00	437.6	COG0809	S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase)	348
2918744371	709	96.46	18	702	23	676	0.0e+00	783.4	COG1200	RecG-like helicase	677
2918744372	312	98.67	1	301	1	297	5.2e-45	149	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918744374	390	94.21	2	385	22	395	3.3e-108	356.5	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
2918744375	300	93.99	1	277	13	278	6.3e-49	161.3	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918744376	245	91.67	3	240	18	226	1.5e-66	219	COG0765	ABC-type amino acid transport system, permease component	222
2918744377	229	93.42	2	228	14	226	3.4e-69	227.5	COG0765	ABC-type amino acid transport system, permease component	222
2918744378	166	66.46	42	162	52	156	1.6e-34	113.9	COG4454	Uncharacterized copper-binding protein, cupredoxin-like subfamily	158
2918744379	321	97.34	1	316	1	293	1.1e-64	213.6	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918744380	188	98.09	31	187	4	157	2.7e-52	171.5	COG0783	DNA-binding ferritin-like protein (oxidative damage protectant)	156
2918744381	286	96.9	1	284	8	288	1.1e-77	255.5	COG0382	4-hydroxybenzoate polyprenyltransferase	289
2918744382	155	67.3	1	148	21	127	4.3e-24	79.2	COG2030	Acyl dehydratase	159
2918744383	285	98.51	17	281	4	267	1.2e-83	275.2	COG0345	Pyrroline-5-carboxylate reductase	266
2918744384	380	81.31	45	379	74	408	1.5e-30	100.5	COG4222	Uncharacterized conserved protein	391
2918744385	122	100	1	122	1	123	2.5e-56	183.6	COG0093	Ribosomal protein L14	122
2918744386	110	97.22	1	108	3	107	2.7e-26	86.7	COG0198	Ribosomal protein L24	104
2918744387	179	99.44	1	179	1	179	6.8e-80	261.6	COG0094	Ribosomal protein L5	180
2918744388	101	98.36	41	101	2	61	1.1e-25	83.5	COG0199	Ribosomal protein S14	61
2918744389	131	99.25	1	131	1	132	1.2e-52	172	COG0096	Ribosomal protein S8	132
2918744390	171	94.97	1	171	8	177	5.5e-63	206.4	COG0097	Ribosomal protein L6P/L9E	178
2918744391	122	96.83	1	122	5	126	2.2e-35	116.6	COG0256	Ribosomal protein L18	125
2918744392	172	90.22	1	172	16	181	5.8e-67	219.3	COG0098	Ribosomal protein S5	181
2918744393	61	96.36	8	61	1	53	1.7e-25	83.2	COG1841	Ribosomal protein L30/L7E	55
2918744394	143	97.4	1	143	1	150	1.3e-41	137	COG0200	Ribosomal protein L15	152
2918744395	437	97.05	2	433	9	435	0.0e+00	517.3	COG0201	Preprotein translocase subunit SecY	436
2918744396	37	100	1	37	1	38	5.1e-23	75.1	COG0257	Ribosomal protein L36	38
2918744397	121	97.52	1	121	1	118	2.4e-50	164.6	COG0099	Ribosomal protein S13	121
2918744398	134	96.92	1	134	5	130	1.1e-57	188.6	COG0100	Ribosomal protein S11	129
2918744399	207	99.52	1	207	2	210	3.1e-67	221	COG0522	Ribosomal protein S4 or related protein	205
2918744400	329	98.43	5	328	2	315	3.4e-117	385.7	COG0202	DNA-directed RNA polymerase, alpha subunit/40 kD subunit	317
2918744401	132	100	1	116	1	116	1.7e-51	167.9	COG0203	Ribosomal protein L17	116
2918744404	190	53.08	8	120	1	69	7.8e-16	53.4	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918744406	132	95.59	1	132	6	135	3.0e-28	93.1	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
2918744407	542	97.64	28	542	4	542	1.3e-121	401.1	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
2918744408	397	95.49	14	397	14	394	9.6e-98	322.4	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918744409	284	98.49	21	281	5	265	3.4e-69	227.7	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918744410	158	94.74	13	149	2	127	1.6e-24	81	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918744411	778	88.55	2	395	4	351	2.7e-52	172.9	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2918744411	778	96.69	397	762	4	354	1.2e-104	344.7	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
2918744412	422	98.25	99	396	6	286	1.1e-99	327.7	COG2230	Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases	283
2918744414	339	98.12	10	337	4	316	2.3e-92	304	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918744415	308	98.34	2	302	3	298	1.3e-75	249.6	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918744416	253	98.88	10	252	3	267	2.9e-69	228.1	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918744417	140	94.74	7	138	6	131	6.1e-20	66.2	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918744418	321	99.07	6	321	2	322	4.0e-107	352.4	COG0022	Pyruvate/2-oxoglutarate/acetoin dehydrogenase complex, dehydrogenase (E1) component	324
2918744419	337	87.71	3	335	30	343	1.3e-95	313.9	COG1071	TPP-dependent pyruvate or acetoin dehydrogenase subunit alpha	358
2918744420	704	97.36	5	703	16	789	5.8e-73	241.4	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2918744421	852	38.53	634	852	368	597	1.2e-90	194.7	COG0369	Sulfite reductase, alpha subunit (flavoprotein)	587
2918744421	852	43.22	356	642	51	308	1.2e-90	103.3	COG0369	Sulfite reductase, alpha subunit (flavoprotein)	587
2918744422	288	97.34	1	288	3	295	1.7e-58	193.4	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918744423	143	97.83	5	143	3	137	4.5e-61	199.6	COG3565	Predicted dioxygenase of extradiol dioxygenase family	138
2918744424	340	97.36	1	329	9	340	1.0e-110	364.8	COG4213	ABC-type xylose transport system, periplasmic component	341
2918744425	396	95.43	4	393	18	393	2.1e-114	377	COG4214	ABC-type xylose transport system, permease component	394
2918744426	258	48.3	4	258	5	246	1.5e-87	288.9	COG1129	ABC-type sugar transport system, ATPase component	500
2918744427	387	25.81	281	366	226	305	1.6e-41	7.3	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
2918744427	387	60.97	76	288	7	195	1.6e-41	133.4	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
2918744428	806	99.74	14	805	3	773	0.0e+00	1025	COG4993	Glucose dehydrogenase	773
2918744429	427	6.7	325	415	567	607	1.7e-49	33	COG3284	Transcriptional regulator of acetoin/glycerol metabolism	606
2918744429	427	42.65	21	319	17	277	1.7e-49	129.9	COG3284	Transcriptional regulator of acetoin/glycerol metabolism	606
2918744430	697	16.16	254	396	176	239	1.1e-30	10.2	COG1520	Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat	370
2918744430	697	23.23	485	621	268	359	1.1e-30	23.7	COG1520	Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat	370
2918744430	697	39.9	23	231	84	241	1.1e-30	77.9	COG1520	Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat	370
2918744431	326	75	259	326	18	77	5.9e-17	55	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2918744433	324	98.12	1	323	6	318	8.5e-88	289.1	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918744434	396	22.76	153	241	231	301	1.9e-18	20.6	COG0501	Zn-dependent protease with chaperone function	302
2918744434	396	46.47	5	157	34	178	1.9e-18	39.4	COG0501	Zn-dependent protease with chaperone function	302
2918744435	190	93.88	11	186	3	186	1.5e-44	146.5	COG0693	Putative intracellular protease/amidase	188
2918744437	423	92.01	2	417	21	423	1.1e-57	189.2	COG1541	Phenylacetate-coenzyme A ligase PaaK, adenylate-forming domain family	438
2918744438	270	99.16	5	248	3	237	4.5e-86	282.4	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2918744439	443	79.51	33	406	19	309	2.8e-12	40.8	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918744440	354	96.59	22	346	7	318	1.9e-74	245.3	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918744441	309	98.34	1	307	2	297	9.3e-63	207	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2918744442	262	98.82	7	260	3	253	3.8e-94	309.3	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2918744443	651	96.74	2	615	15	607	0.0e+00	456.3	COG1022	Long-chain acyl-CoA synthetase (AMP-forming)	613
2918744444	264	83.49	27	235	34	215	2.1e-20	67.7	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2918744447	256	91.79	1	252	5	250	7.7e-37	121.9	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918744449	348	63.46	80	324	22	186	3.2e-27	90.1	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2918744450	325	97.49	4	323	6	316	5.7e-97	319.2	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918744451	277	92.93	1	272	12	274	2.9e-49	162.4	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918744452	221	92.11	2	221	16	225	1.1e-61	203	COG0765	ABC-type amino acid transport system, permease component	222
2918744453	215	90.79	1	215	17	223	1.9e-58	192.4	COG0765	ABC-type amino acid transport system, permease component	222
2918744454	272	98.35	8	259	2	239	1.4e-97	320.2	COG1126	ABC-type polar amino acid transport system, ATPase component	240
2918744455	442	19.86	23	156	21	103	6.6e-37	19.4	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
2918744455	442	59.57	179	430	169	417	6.6e-37	101.7	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
2918744456	235	76.89	3	234	45	247	1.5e-49	163	COG3665	Uncharacterized conserved protein YcgI, DUF1989 family	264
2918744457	211	48.46	28	188	2	64	4.9e-13	43.3	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918744458	314	98.71	11	310	2	306	4.5e-89	293.2	COG0010	Arginase family enzyme	305
2918744459	125	78.08	7	124	7	120	2.3e-08	25.7	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2918744460	193	96.59	1	193	2	199	2.4e-73	241.1	COG0605	Superoxide dismutase	204
2918744461	222	93.61	12	222	13	217	1.8e-59	195.9	COG2345	Predicted transcriptional regulator, ArsR family	218
2918744464	601	98.75	2	599	7	559	0.0e+00	802.5	COG2060	K+-transporting ATPase, A chain	560
2918744465	698	99.41	4	698	4	681	0.0e+00	1097.3	COG2216	High-affinity K+ transport system, ATPase chain B	681
2918744466	189	98.94	1	189	2	188	4.8e-73	239.6	COG2156	K+-transporting ATPase, c chain	190
2918744468	918	99.22	1	917	4	893	0.0e+00	978	COG2205	K+-sensing histidine kinase KdpD	890
2918744469	230	97.84	4	230	3	229	1.5e-75	248.2	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918744470	376	65.56	7	261	12	228	9.1e-28	90.6	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2918744471	192	50.8	27	166	47	173	2.0e-22	74.3	COG2365	Protein tyrosine/serine phosphatase	249
2918744473	379	98.88	3	379	1	354	3.5e-55	181.8	COG0707	UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase	357
2918744474	273	95.12	6	273	3	236	8.8e-68	221.7	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
2918744476	218	98.28	1	218	1	228	5.7e-72	236.4	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918744477	474	84.26	17	469	61	392	1.8e-60	200.2	COG0642	Signal transduction histidine kinase	336
2918744479	235	98.37	2	232	4	244	1.9e-63	208.6	COG0580	Glycerol uptake facilitator and related aquaporins (Major Intrinsic Protein Family)	241
2918744480	336	97.28	8	336	10	331	5.6e-84	276.9	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2918744481	305	98.01	3	304	3	297	8.7e-71	233.8	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918744482	329	98.67	29	327	3	299	8.1e-70	230.2	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
2918744483	678	41.53	404	678	362	621	0.0e+00	252.3	COG0326	Molecular chaperone, HSP90 family	623
2918744483	678	57.99	3	383	4	366	0.0e+00	558.7	COG0326	Molecular chaperone, HSP90 family	623
2918744485	301	96.01	1	293	2	290	4.4e-59	195.2	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918744486	381	92.52	1	371	6	376	6.4e-128	421.6	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2918744487	328	97.81	5	327	7	318	1.2e-99	328	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918744488	569	8.77	458	546	121	155	2.6e-74	2.2	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918744488	569	89.97	54	455	36	394	2.6e-74	245.5	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918744489	298	99	1	298	1	298	6.7e-63	207.9	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918744490	344	97.91	8	344	5	332	2.6e-74	244.5	COG2334	Ser/Thr protein kinase RdoA involved in Cpx stress response, MazF antagonist	331
2918744492	141	96.5	1	141	5	142	1.5e-43	143.1	COG1764	Organic hydroperoxide reductase OsmC/OhrA	143
2918744493	141	72.18	14	140	4	99	1.6e-27	90.5	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918744494	280	82.26	52	279	44	261	7.8e-17	55.6	COG1682	ABC-type polysaccharide/polyol phosphate export permease	263
2918744495	312	98.04	7	306	7	306	3.2e-85	280.8	COG1131	ABC-type multidrug transport system, ATPase component	293
2918744496	296	97.67	2	295	2	295	1.2e-69	230	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918744497	219	96.28	12	215	1	207	4.2e-47	155.3	COG0625	Glutathione S-transferase	211
2918744498	323	32.76	198	286	56	112	1.4e-30	17.6	COG3576	Predicted flavin-nucleotide-binding protein, pyridoxine 5'-phosphate oxidase superfamily	173
2918744498	323	89.08	6	205	1	155	1.4e-30	82.4	COG3576	Predicted flavin-nucleotide-binding protein, pyridoxine 5'-phosphate oxidase superfamily	173
2918744499	390	89.55	3	388	29	405	5.5e-52	171.5	COG2124	Cytochrome P450	411
2918744500	231	76.27	5	102	15	104	1.2e-13	45.6	COG0640	DNA-binding transcriptional regulator, ArsR family	110
2918744501	336	95.61	15	336	11	315	1.1e-61	203.3	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918744502	505	99.58	213	484	1	236	9.8e-59	192.8	COG0775	Nucleoside phosphorylase	234
2918744503	182	63.9	18	176	11	141	2.2e-26	87.3	COG1611	Predicted Rossmann fold nucleotide-binding protein	205
2918744504	273	47.06	2	273	15	270	9.8e-43	140.9	COG1178	ABC-type Fe3+ transport system, permease component	540
2918744505	362	98.01	66	362	2	296	1.1e-42	141	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
2918744506	342	89.52	1	339	8	323	1.6e-107	354.4	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
2918744507	255	92.13	1	255	15	260	2.5e-47	156	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
2918744508	302	97.67	6	299	2	295	4.7e-54	178.8	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918744509	298	98.71	1	298	1	305	3.5e-83	274	COG1893	Ketopantoate reductase	307
2918744510	452	99.34	2	447	3	454	0.0e+00	486.5	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
2918744513	637	99.11	1	637	4	446	0.0e+00	613.4	COG4664	TRAP-type mannitol/chloroaromatic compound transport system, large permease component	447
2918744514	222	96.7	1	182	5	180	2.9e-55	181.2	COG4665	TRAP-type mannitol/chloroaromatic compound transport system, small permease component	182
2918744515	369	93.66	5	363	17	356	1.6e-119	393.7	COG4663	TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component	363
2918744516	137	92.98	11	137	7	112	8.0e-17	55.6	COG0607	Rhodanese-related sulfurtransferase	110
2918744517	153	78.67	1	153	55	279	2.1e-25	82.8	COG1652	Nucleoid-associated protein YgaU, contains BON and LysM domains	269
2918744518	256	98.81	4	255	2	251	3.7e-46	152.3	COG1521	Pantothenate kinase type III	251
2918744519	271	97.36	10	268	8	265	4.6e-58	191.2	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918744520	282	86.02	1	282	1	283	7.6e-113	371.6	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
2918744521	400	99.24	1	399	1	391	0.0e+00	581	COG0027	Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase)	394
2918744522	313	92.14	1	312	24	316	5.5e-88	290	COG0657	Acetyl esterase/lipase	312
2918744523	276	79.55	142	267	21	125	2.0e-15	50.9	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918744524	291	98.67	1	290	4	300	1.1e-72	239.7	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2918744525	358	95.98	17	332	9	318	2.3e-84	277.8	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918744526	274	99.21	4	262	3	254	9.8e-92	301.4	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2918744527	257	99.16	3	239	3	237	1.3e-95	313.7	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2918744528	626	96.57	22	626	16	607	0.0e+00	557.5	COG1022	Long-chain acyl-CoA synthetase (AMP-forming)	613
2918744529	388	96.99	15	388	6	360	6.5e-54	178	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918744530	153	95.51	1	153	1	149	1.3e-61	201.7	COG2947	Predicted RNA-binding protein, contains PUA-like domain	156
2918744531	217	98.54	1	213	3	204	4.4e-57	187.4	COG2095	Small neutral amino acid transporter SnatA, MarC family	203
2918744532	248	97.76	2	248	6	267	2.4e-62	205.5	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918744533	201	96.55	1	201	6	201	6.0e-52	170.9	COG3917	2-hydroxychromene-2-carboxylate isomerase	203
2918744534	227	99.16	1	227	1	235	1.6e-56	186	COG0412	Dienelactone hydrolase	236
2918744535	301	98.34	2	297	2	297	1.8e-71	235.9	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918744537	386	70.43	52	382	98	328	1.8e-39	128.3	COG0598	Mg2+ and Co2+ transporter CorA	322
2918744538	336	98.79	5	336	4	329	0.0e+00	482	COG0113	Delta-aminolevulinic acid dehydratase, porphobilinogen synthase	330
2918744539	142	95.3	1	142	8	149	2.3e-49	162.2	COG1981	Uncharacterized membrane protein	149
2918744540	371	72	2	138	27	134	6.1e-14	46.9	COG5652	VanZ like family protein (function unknown)	148
2918744541	117	87.5	56	116	2	57	3.9e-24	79	COG3411	(2Fe-2S) ferredoxin	64
2918744542	210	96.19	2	209	3	204	4.1e-59	193.9	COG2945	Alpha/beta superfamily hydrolase	210
2918744543	389	96.18	1	389	12	389	1.0e-116	385	COG1686	D-alanyl-D-alanine carboxypeptidase	389
2918744544	125	95.35	1	123	7	129	6.2e-62	201.5	COG0048	Ribosomal protein S12	129
2918744545	157	99.32	2	150	2	148	1.7e-59	194.3	COG0049	Ribosomal protein S7	148
2918744546	699	99.31	1	699	1	724	0.0e+00	989.8	COG0480	Translation elongation factor EF-G, a GTPase	697
2918744547	30	7.61	1	30	1	30	1.9e-15	51.2	COG0050	Translation elongation factor EF-Tu, a GTPase	394
2918744549	931	84.13	869	929	3	55	2.7e-06	20.8	COG2906	Bacterioferritin-associated ferredoxin	63
2918744549	931	94.44	1	714	45	809	0.0e+00	621.4	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
2918744550	301	88.24	1	301	4	303	1.9e-56	186.1	COG0547	Anthranilate phosphoribosyltransferase	338
2918744551	268	95.49	8	264	3	235	2.0e-82	271.1	COG0007	Uroporphyrinogen-III methylase (siroheme synthase)	244
2918744552	371	68.27	8	256	5	245	8.7e-108	350	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
2918744553	422	91.01	8	421	7	350	1.3e-31	103.8	COG0687	Spermidine/putrescine-binding periplasmic protein	363
2918744554	305	91.32	9	304	11	273	7.3e-73	239.8	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
2918744555	290	93.26	1	288	10	258	9.6e-57	186.7	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
2918744556	376	90.39	88	376	21	274	3.1e-66	218.6	COG3000	Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily	271
2918744557	260	16.45	181	232	179	216	4.0e-08	5.5	COG3863	Uncharacterized protein YycO	231
2918744557	260	40.26	33	154	79	171	4.0e-08	20.5	COG3863	Uncharacterized protein YycO	231
2918744558	413	98.03	7	413	4	402	0.0e+00	432.3	COG2081	Predicted flavoprotein YhiN	408
2918744559	70	95.52	1	66	1	64	1.0e-29	97	COG0828	Ribosomal protein S21	67
2918744560	149	99.32	1	147	1	147	1.0e-56	186.1	COG1610	Uncharacterized conserved protein YqeY	148
2918744561	158	58.72	3	155	18	118	1.3e-14	49.1	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2918744562	255	96.53	13	255	7	256	6.0e-20	66.1	COG0730	Uncharacterized membrane protein YfcA	258
2918744563	301	98.67	3	301	1	297	1.3e-60	200.3	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918744564	180	96.51	8	177	5	170	1.3e-38	127.1	COG3613	Nucleoside 2-deoxyribosyltransferase	172
2918744567	119	82.71	1	112	6	115	3.9e-11	37.8	COG2346	Truncated hemoglobin YjbI	133
2918744568	1023	85	943	1016	11	78	6.0e-24	77	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2918744569	190	43.25	3	173	26	166	3.0e-06	21.5	COG2203	GAF domain	175
2918744570	321	98.43	2	320	4	317	6.0e-97	319.2	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918744571	611	97.43	1	611	14	544	1.4e-123	408.2	COG0405	Gamma-glutamyltranspeptidase	539
2918744572	311	97.01	13	311	2	293	1.3e-37	124.8	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918744573	313	80.3	174	310	20	125	1.5e-26	86.6	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918744574	264	79.12	5	264	55	270	8.6e-72	236.6	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
2918744575	456	99.12	19	456	4	455	6.5e-117	385.6	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
2918744576	218	84.49	18	204	25	182	1.0e-47	156.6	COG3028	Ribosomal 50S subunit-associated protein YjgA (function unknown), DUF615 family	187
2918744577	194	97.06	1	180	4	168	7.4e-58	189.4	COG0521	Molybdopterin biosynthesis enzyme MoaB	169
2918744578	1051	99.61	1	1046	1	1026	0.0e+00	1427.7	COG3696	Cu/Ag efflux pump CusA	1027
2918744579	432	93.59	5	430	12	376	3.0e-40	132.7	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918744580	439	96.74	3	438	12	456	1.4e-58	193.4	COG1538	Outer membrane protein TolC	457
2918744582	225	99.14	1	223	1	230	1.1e-83	274.7	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918744583	443	84.01	89	443	57	387	6.4e-55	181.5	COG0642	Signal transduction histidine kinase	336
2918744584	420	97	1	415	5	392	2.3e-74	245.1	COG0475	Kef-type K+ transport system, membrane component KefB	397
2918744585	761	98.91	47	760	6	728	0.0e+00	734	COG2217	Cation transport ATPase	713
2918744586	157	98.48	1	119	1	130	4.3e-32	105.7	COG0789	DNA-binding transcriptional regulator, MerR family	124
2918744587	256	88.78	1	191	5	178	4.4e-75	245.9	COG1045	Serine acetyltransferase	194
2918744588	243	95.56	1	242	4	240	1.6e-71	235.4	COG0565	tRNA C32,U32 (ribose-2'-O)-methylase TrmJ or a related methyltransferase	242
2918744589	352	98.07	6	264	2	255	2.0e-86	284	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
2918744590	746	86.3	13	737	25	616	2.3e-41	136.1	COG1289	Uncharacterized membrane protein YccC	674
2918744591	353	56.73	13	338	61	254	2.7e-25	83.9	COG0668	Small-conductance mechanosensitive channel	316
2918744592	152	90.51	1	144	4	146	2.2e-32	106.9	COG1522	DNA-binding transcriptional regulator, Lrp family	154
2918744593	207	99.04	1	205	1	206	4.2e-31	102.4	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
2918744594	405	97.77	1	396	8	401	9.3e-83	273.1	COG2311	Uncharacterized membrane protein YeiB	394
2918744595	322	98.01	10	310	2	296	1.0e-54	180.9	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918744596	337	97.81	17	335	6	317	2.2e-77	254.7	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918744597	174	86.47	8	146	15	129	1.9e-22	74.3	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918744598	335	96.87	13	333	10	318	4.3e-72	237.4	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918744599	330	98.75	8	330	4	318	6.4e-71	233.6	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918744600	438	41.8	1	205	4	207	3.8e-77	130.9	COG3119	Arylsulfatase A or related enzyme	475
2918744600	438	55.53	156	426	200	470	3.8e-77	136.6	COG3119	Arylsulfatase A or related enzyme	475
2918744602	1107	16.48	322	391	9	66	1.7e-22	8.6	COG3614	Extracellular (periplasmic) sensor domain CHASE1 (specificity unknown)	348
2918744602	1107	49.72	2	212	13	187	1.7e-22	64.4	COG3614	Extracellular (periplasmic) sensor domain CHASE1 (specificity unknown)	348
2918744602	1107	64.71	602	1099	216	644	2.5e-121	400.1	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2918744603	275	75.43	1	249	17	234	3.2e-48	158.6	COG1639	HD-like signal output (HDOD) domain, no enzymatic activity	289
2918744604	205	63.5	51	198	4	90	5.9e-27	88.6	COG1695	DNA-binding transcriptional regulator, PadR family	138
2918744605	278	96.99	12	273	7	264	4.9e-80	263.2	COG2375	NADPH-dependent ferric siderophore reductase, contains FAD-binding and SIP domains	265
2918744606	325	91.46	3	325	29	328	8.9e-71	232.9	COG0598	Mg2+ and Co2+ transporter CorA	322
2918744608	885	99.77	13	876	3	854	0.0e+00	945.5	COG0249	DNA mismatch repair ATPase MutS	843
2918744609	279	96.47	1	260	1	246	2.5e-111	365.4	COG3484	Predicted proteasome-type protease	255
2918744610	269	92.2	2	267	23	294	1.7e-19	65.1	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918744612	222	97.16	13	222	3	207	3.9e-33	109.4	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918744613	783	97.76	466	722	6	267	1.7e-55	179.7	COG1018	Ferredoxin-NADP reductase	266
2918744613	783	98.1	20	440	8	420	1.1e-90	298.9	COG2124	Cytochrome P450	411
2918744614	322	99.37	1	321	1	317	6.5e-85	279.7	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918744615	273	99.59	22	269	1	245	9.3e-48	156.9	COG1414	DNA-binding transcriptional regulator, IclR family	246
2918744616	274	98.53	1	268	3	271	3.2e-103	339.5	COG1968	Undecaprenyl pyrophosphate phosphatase UppP	270
2918744617	217	27.83	134	216	50	113	2.2e-06	12	COG1794	Aspartate/glutamate racemase	230
2918744617	217	29.13	4	126	60	126	2.2e-06	8.8	COG1794	Aspartate/glutamate racemase	230
2918744618	304	96.47	3	285	7	279	2.2e-55	182.5	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918744619	444	95.08	1	443	20	444	0.0e+00	483.6	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
2918744620	288	96.45	1	277	6	277	2.7e-62	205	COG1737	DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains	281
2918744622	497	98.04	21	478	1	451	1.1e-106	351.9	COG1538	Outer membrane protein TolC	457
2918744623	1078	99.9	2	1062	1	1013	0.0e+00	1053.6	COG0841	Multidrug efflux pump subunit AcrB	1009
2918744624	1035	99.7	2	1022	3	1013	0.0e+00	1083.4	COG0841	Multidrug efflux pump subunit AcrB	1009
2918744625	445	97.18	28	409	7	385	3.2e-64	212	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918744627	317	78.29	2	256	48	267	2.7e-45	149.5	COG3000	Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily	271
2918744629	339	22.67	156	335	291	375	3.8e-11	35.8	COG4585	Signal transduction histidine kinase	365
2918744629	339	31.47	64	235	56	173	3.8e-11	4.2	COG4585	Signal transduction histidine kinase	365
2918744630	281	96.77	3	281	4	243	2.0e-55	182.5	COG3279	DNA-binding response regulator, LytR/AlgR family	244
2918744632	604	98.54	46	581	8	480	4.2e-124	409.7	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
2918744633	100	40.25	1	82	6	69	1.1e-03	13.2	COG3126	Uncharacterized lipoprotein YbaY	158
2918744634	297	44.3	32	297	165	304	1.8e-36	121.4	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
2918744635	311	33.33	10	310	44	153	6.4e-12	37.7	COG3608	Predicted deacylase	331
2918744636	322	87.69	39	320	3	230	2.4e-29	97.2	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2918744637	400	98.54	5	399	3	408	6.0e-100	329.4	COG0004	Ammonia channel protein AmtB	409
2918744639	414	97.17	1	402	5	382	8.2e-13	42.5	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
2918744640	139	85.11	1	134	13	132	2.7e-22	73.6	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
2918744642	145	85.52	1	138	17	140	2.2e-28	92.9	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
2918744643	314	87.77	1	295	24	310	3.5e-62	205.1	COG1161	Ribosome biogenesis GTPase A	322
2918744645	142	88.96	18	122	19	163	3.6e-24	80.4	COG0517	CBS domain	117
2918744646	119	91.82	1	116	1	101	2.7e-06	22.3	COG1544	Ribosome-associated translation inhibitor RaiA	110
2918744647	148	95.45	9	130	1	126	1.7e-23	77.9	COG0789	DNA-binding transcriptional regulator, MerR family	124
2918744648	143	97.06	1	134	4	135	3.0e-24	80.4	COG3631	Ketosteroid isomerase-related protein	133
2918744649	307	79.1	6	242	2	213	2.4e-54	179.5	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918744650	126	53.55	3	125	4	116	6.4e-18	59.7	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918744651	518	99.23	1	502	3	516	0.0e+00	500.7	COG2918	Gamma-glutamylcysteine synthetase	518
2918744652	99	94.95	1	96	3	96	4.4e-21	69.3	COG1359	Quinol monooxygenase YgiN	100
2918744653	223	94.26	1	220	9	205	5.3e-55	180.8	COG0400	Predicted esterase	207
2918744654	155	92.41	9	155	7	140	2.0e-21	70.9	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
2918744655	397	99.39	5	374	1	324	7.7e-111	365.2	COG0523	GTPase, G3E family	323
2918744656	220	95.81	7	211	2	207	2.7e-26	87.2	COG0625	Glutathione S-transferase	211
2918744657	301	97.67	1	299	1	294	2.6e-52	173	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918744658	443	47.52	236	436	8	189	2.0e-35	28	COG0477	MFS family permease	338
2918744658	443	64.23	18	273	2	247	2.0e-35	93.1	COG0477	MFS family permease	338
2918744660	265	90.94	4	264	25	265	1.1e-57	190	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918744662	90	85.37	1	78	4	73	1.6e-10	35.3	COG5460	Uncharacterized conserved protein, DUF2164 family	82
2918744663	395	19.11	303	392	96	172	3.0e-23	18	COG3391	DNA-binding beta-propeller fold protein YncE	381
2918744663	395	44.91	31	253	106	286	3.0e-23	46.8	COG3391	DNA-binding beta-propeller fold protein YncE	381
2918744664	67	25.37	4	65	91	141	2.0e-04	15.3	COG4723	Phage-related protein, tail component	198
2918744665	302	99.67	1	299	1	302	3.2e-117	385.7	COG2354	Uncharacterized membrane protein MutK, may be involved in DNA repair	303
2918744666	172	50.26	1	153	70	164	4.0e-15	50.7	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
2918744668	100	55.88	11	99	10	85	2.7e-35	116.2	COG4628	Uncharacterized conserved protein, DUF2132 family	136
2918744669	93	75.73	3	91	19	96	2.9e-15	50.5	COG0633	Ferredoxin	102
2918744670	422	27.15	284	419	73	176	1.2e-10	8.8	COG0477	MFS family permease	338
2918744670	422	71.02	19	288	4	275	1.2e-10	33.6	COG0477	MFS family permease	338
2918744671	225	71.92	1	215	82	291	3.6e-65	215	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
2918744672	147	96.86	1	146	4	157	1.1e-33	111.8	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2918744673	250	86.28	33	247	24	218	1.3e-50	166.3	COG4340	Uncharacterized protein	226
2918744674	94	73.48	1	94	28	124	2.8e-35	115.5	COG2343	Uncharacterized conserved protein, DUF427 family	132
2918744675	337	95.36	17	336	12	319	1.4e-101	334.1	COG4301	Uncharacterized conserved protein, contains predicted SAM-dependent methyltransferase domain	321
2918744676	418	27.03	332	418	243	332	2.9e-52	66.2	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
2918744676	418	56.46	91	337	5	192	2.9e-52	105.9	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
2918744677	448	98.54	7	436	2	405	2.0e-129	426.7	COG1252	NADH dehydrogenase, FAD-containing subunit	405
2918744678	641	99.36	8	641	4	622	0.0e+00	702.1	COG3211	Secreted phosphatase, PhoX family	616
2918744679	175	80.93	2	169	31	187	7.5e-34	111.1	COG1525	Endonuclease YncB, thermonuclease family	192
2918744680	563	96.3	17	563	12	558	8.7e-125	411.7	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2918744681	146	96.5	3	143	5	142	7.3e-29	95.3	COG1764	Organic hydroperoxide reductase OsmC/OhrA	143
2918744682	325	97.81	1	324	6	317	6.7e-92	302.7	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918744683	257	92.24	1	218	15	228	3.8e-55	181.6	COG1802	DNA-binding transcriptional regulator, GntR family	230
2918744684	266	94.35	5	265	9	275	5.6e-52	171.3	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918744685	218	90.35	2	217	19	224	1.5e-64	212.2	COG0765	ABC-type amino acid transport system, permease component	222
2918744686	217	92.11	1	216	15	224	2.1e-66	218.5	COG0765	ABC-type amino acid transport system, permease component	222
2918744687	256	99.17	14	255	2	241	8.6e-109	356.9	COG1126	ABC-type polar amino acid transport system, ATPase component	240
2918744688	321	94.36	3	306	3	253	3.8e-80	263.9	COG1801	Uncharacterized conserved protein YecE, DUF72 family	263
2918744690	330	94.1	15	318	13	267	1.8e-45	150.2	COG0584	Glycerophosphoryl diester phosphodiesterase	257
2918744692	155	89.26	1	155	15	147	2.1e-46	152	COG3019	Uncharacterized conserved protein	149
2918744693	432	97.42	12	432	5	382	8.7e-57	184.4	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918744694	349	91.95	7	348	12	331	3.0e-90	297.2	COG3191	L-aminopeptidase/D-esterase	348
2918744695	464	60.56	8	296	22	216	7.6e-27	88.2	COG2358	TRAP-type uncharacterized transport system, periplasmic component	321
2918744696	163	93.18	5	157	1	123	2.3e-30	100.2	COG0789	DNA-binding transcriptional regulator, MerR family	124
2918744697	139	81.45	13	135	20	120	4.4e-29	95.8	COG0599	Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family	124
2918744698	279	49.38	17	273	37	235	1.3e-12	39.9	COG3391	DNA-binding beta-propeller fold protein YncE	381
2918744699	553	99.44	3	536	3	534	0.0e+00	589.4	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
2918744700	597	73.27	1	509	29	409	0.0e+00	490.5	COG0513	Superfamily II DNA and RNA helicase	513
2918744701	337	84.05	31	336	32	247	3.7e-12	39	COG3568	Metal-dependent hydrolase, endonuclease/exonuclease/phosphatase family	259
2918744702	355	99.71	1	349	1	349	0.0e+00	473.4	COG3839	ABC-type sugar transport system, ATPase component	338
2918744703	283	96.82	1	282	10	283	1.8e-73	242.1	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
2918744704	292	93.62	18	292	11	289	2.1e-58	192.5	COG1175	ABC-type sugar transport system, permease component	295
2918744705	461	98.65	1	461	2	438	5.9e-48	159	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
2918744706	247	92.53	2	233	12	234	7.6e-61	200	COG2186	DNA-binding transcriptional regulator, FadR family	241
2918744707	578	98.27	1	566	7	574	0.0e+00	619.9	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
2918744708	302	94.44	1	297	6	294	4.9e-81	266.7	COG3734	2-keto-3-deoxy-galactonokinase	306
2918744709	213	96.68	3	212	3	206	3.2e-62	204.2	COG0800	2-keto-3-deoxy-6-phosphogluconate aldolase	211
2918744710	245	96.88	8	232	3	219	2.2e-39	130	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
2918744712	468	95.43	7	457	10	448	1.4e-69	229.1	COG0534	Na+-driven multidrug efflux pump	455
2918744713	411	47.78	217	411	8	190	1.6e-16	25.2	COG0477	MFS family permease	338
2918744713	411	68.67	5	256	4	266	1.6e-16	34	COG0477	MFS family permease	338
2918744714	165	86.47	19	150	2	116	9.6e-17	55.7	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918744715	182	85.11	42	180	19	138	3.6e-35	115.2	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
2918744716	231	97.69	13	231	4	214	8.7e-22	72.4	COG0778	Nitroreductase	207
2918744719	353	99.67	51	352	1	300	8.1e-65	213.6	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
2918744720	555	97.06	10	553	9	536	3.2e-128	422.9	COG1178	ABC-type Fe3+ transport system, permease component	540
2918744721	227	59.77	1	223	6	216	4.9e-83	273.8	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
2918744722	226	95.81	6	213	1	206	6.6e-49	161.2	COG0625	Glutathione S-transferase	211
2918744723	146	99.32	1	126	1	145	1.9e-25	85.5	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2918744725	353	92.8	3	353	11	371	8.1e-45	147.9	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
2918744726	242	96.1	8	242	4	225	2.0e-24	81.2	COG1011	FMN phosphatase YigB, HAD superfamily	229
2918744727	211	97.63	2	211	4	209	8.0e-75	245.4	COG0800	2-keto-3-deoxy-6-phosphogluconate aldolase	211
2918744728	608	98.27	4	608	5	572	0.0e+00	622.7	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
2918744729	183	53.27	49	183	92	197	1.5e-15	52	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
2918744730	242	94.74	15	201	9	188	2.7e-51	168.4	COG3703	Cation transport regulator ChaC	190
2918744731	180	90.71	4	178	17	182	1.7e-38	127	COG2032	Cu/Zn superoxide dismutase	179
2918744732	190	19	5	57	8	45	2.4e-31	22.7	COG2068	CTP:molybdopterin cytidylyltransferase MocA	199
2918744732	190	58	54	184	81	196	2.4e-31	82.7	COG2068	CTP:molybdopterin cytidylyltransferase MocA	199
2918744733	220	98.6	9	220	4	214	6.3e-84	275.3	COG0259	Pyridoxine/pyridoxamine 5'-phosphate oxidase	214
2918744734	401	76.38	188	398	46	197	5.1e-18	59.8	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
2918744735	127	21.37	14	121	283	379	2.2e+00	1.3	COG3846	Type IV secretory pathway, TrbL components	452
2918744736	316	98.4	2	316	4	311	6.4e-46	151.3	COG0679	Predicted permease	311
2918744737	702	25.91	4	222	18	223	2.0e-59	67.8	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2918744737	702	53.58	233	702	370	795	2.0e-59	135.3	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2918744739	183	91.38	3	175	5	163	1.2e-70	231.6	COG0225	Peptide methionine sulfoxide reductase MsrA	174
2918744740	225	85.65	13	221	6	184	3.0e-26	87.8	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918744741	225	87.68	10	218	3	187	5.2e-53	174.2	COG2518	Protein-L-isoaspartate O-methyltransferase	209
2918744742	112	92.98	1	112	7	112	8.2e-22	72	COG0607	Rhodanese-related sulfurtransferase	110
2918744743	511	95.87	2	449	13	453	1.9e-74	245.6	COG1538	Outer membrane protein TolC	457
2918744744	460	98.56	5	435	3	414	2.9e-115	377.3	COG1519	3-deoxy-D-manno-octulosonic-acid transferase	419
2918744745	460	96.86	1	453	11	473	9.2e-121	398.6	COG1109	Phosphomannomutase	464
2918744746	530	80.28	251	515	47	278	2.0e-49	162.6	COG0122	3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase	285
2918744746	530	94.71	7	205	6	184	2.8e-57	187.7	COG2169	Methylphosphotriester-DNA--protein-cysteine methyltransferase (N-terminal fragment of Ada), contains Zn-binding and two AraC-type DNA-binding domains	187
2918744747	164	98.21	7	164	3	167	2.7e-52	172.2	COG0350	O6-methylguanine-DNA--protein-cysteine methyltransferase	168
2918744748	322	95.68	14	305	7	294	1.1e-45	150.8	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918744749	219	89.91	5	219	21	225	2.6e-53	175.8	COG4291	Uncharacterized membrane protein	228
2918744751	296	77.74	29	292	46	279	6.8e-21	69.3	COG3221	ABC-type phosphate/phosphonate transport system, periplasmic component	299
2918744752	234	94.42	21	231	3	205	6.3e-57	187.3	COG0625	Glutathione S-transferase	211
2918744753	205	88.71	1	184	15	179	2.0e-22	71.1	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918744754	71	13	5	71	25	66	3.5e-06	21	COG3712	Periplasmic ferric-dicitrate binding protein FerR, regulates iron transport through sigma-19	322
2918744756	563	95.97	13	560	7	530	0.0e+00	514.5	COG4615	ABC-type siderophore export system, fused ATPase and permease components	546
2918744757	281	86.85	32	269	33	250	3.1e-29	97	COG4114	Ferric iron reductase protein FhuF, involved in iron transport	251
2918744758	281	60.5	102	278	59	179	1.3e-13	42.9	COG0299	Folate-dependent phosphoribosylglycinamide formyltransferase PurN	200
2918744760	443	93.81	1	439	5	413	3.3e-128	422.7	COG3486	Lysine/ornithine N-monooxygenase	436
2918744761	722	97.74	4	722	19	795	6.4e-112	370.2	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2918744762	1357	97.28	1088	1350	2	251	7.3e-18	59	COG3319	Thioesterase domain of type I polyketide synthase or non-ribosomal peptide synthetase	257
2918744762	1357	99.54	273	909	2	646	3.5e-117	387.5	COG1020	Non-ribosomal peptide synthetase component F	642
2918744763	2623	66.22	1026	1095	18	66	1.2e-04	10.9	COG3433	Aryl carrier domain	74
2918744763	2623	72.84	2519	2594	6	64	9.8e-06	14.6	COG0236	Acyl carrier protein	80
2918744763	2623	99.07	1782	2434	7	648	0.0e+00	550.8	COG1020	Non-ribosomal peptide synthetase component F	642
2918744763	2623	99.38	280	935	5	648	0.0e+00	501.5	COG1020	Non-ribosomal peptide synthetase component F	642
2918744764	1113	99.54	279	932	4	648	0.0e+00	569.4	COG1020	Non-ribosomal peptide synthetase component F	642
2918744765	1520	66.22	1444	1503	20	68	3.5e-05	16.4	COG3433	Aryl carrier domain	74
2918744765	1520	98.32	8	1265	8	1174	0.0e+00	1117.3	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
2918744766	1771	59.26	17	482	260	643	0.0e+00	68.9	COG1020	Non-ribosomal peptide synthetase component F	642
2918744766	1771	99.69	924	1577	3	648	0.0e+00	569.1	COG1020	Non-ribosomal peptide synthetase component F	642
2918744767	330	82.58	13	326	31	267	8.9e-14	42.2	COG2175	Taurine dioxygenase, alpha-ketoglutarate-dependent	286
2918744768	229	76.23	16	228	27	196	1.4e-30	100.8	COG2091	Phosphopantetheinyl transferase	223
2918744769	245	94.67	1	240	6	236	2.1e-66	218	COG3208	Surfactin synthase thioesterase subunit	244
2918744770	86	98.59	1	72	1	70	2.7e-27	89	COG3251	Uncharacterized conserved protein YbdZ, MbtH family	71
2918744771	67	16.1	1	67	12	63	4.3e-07	23.9	COG3712	Periplasmic ferric-dicitrate binding protein FerR, regulates iron transport through sigma-19	322
2918744772	181	87.63	4	180	14	176	3.1e-30	99.8	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918744774	194	77.97	19	193	7	183	2.2e-34	112.9	COG2930	Lipid-binding SYLF domain	227
2918744775	484	99.04	64	480	4	417	3.2e-75	248.4	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
2918744776	412	64.22	4	188	66	214	1.6e-13	46.2	COG0671	Membrane-associated phospholipid phosphatase	232
2918744780	462	97.71	1	462	8	476	0.0e+00	487.9	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
2918744781	408	98.24	9	406	7	396	3.8e-128	422.1	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
2918744782	500	97.87	1	481	4	463	0.0e+00	607.7	COG0034	Glutamine phosphoribosylpyrophosphate amidotransferase	470
2918744783	161	85.16	1	161	3	157	4.2e-25	83.4	COG1286	Uncharacterized membrane protein, required for colicin V production	182
2918744784	290	48.74	166	288	113	228	9.8e-26	68.9	COG3147	Cell division protein DedD (periplasmic protein involved in septation)	226
2918744784	290	66.39	31	178	2	159	9.8e-26	20.7	COG3147	Cell division protein DedD (periplasmic protein involved in septation)	226
2918744785	431	97.44	1	423	5	422	5.6e-128	422.1	COG0285	Folylpolyglutamate synthase/Dihydropteroate synthase	427
2918744786	118	95.73	1	117	2	113	6.5e-32	104.8	COG1393	Arsenate reductase and related proteins, glutaredoxin family	117
2918744788	108	97.87	14	108	2	93	2.9e-34	111.9	COG3123	Uncharacterized conserved protein YaiE, UPF0345 family	94
2918744789	446	98.26	8	427	3	398	0.0e+00	450.6	COG0137	Argininosuccinate synthase	403
2918744790	279	89.96	49	279	23	264	8.8e-55	180.6	COG4278	Uncharacterized protein	269
2918744791	350	97.62	1	350	2	288	4.4e-83	273.1	COG0812	UDP-N-acetylenolpyruvoylglucosamine reductase	291
2918744792	161	98.18	1	161	4	165	7.9e-64	209.4	COG1666	Uncharacterized conserved protein YajQ, UPF0234 family	165
2918744793	214	57.67	17	213	90	213	2.3e-37	123.4	COG3577	Predicted aspartyl protease	215
2918744794	117	90.44	1	117	12	134	1.4e-26	87.7	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
2918744795	211	97.07	4	206	6	204	1.2e-69	228.8	COG0344	Phospholipid biosynthesis protein PlsY, probable glycerol-3-phosphate acyltransferase	200
2918744796	163	97.42	9	161	2	152	1.9e-41	135.8	COG2606	Cys-tRNA(Pro) deacylase, prolyl-tRNA editing enzyme YbaK/EbsC	155
2918744797	353	98.75	1	353	1	316	1.3e-92	304.8	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
2918744798	309	98.98	9	309	2	293	2.7e-37	123.7	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918744799	230	97.39	2	230	3	226	4.8e-49	161.8	COG1794	Aspartate/glutamate racemase	230
2918744800	273	97.41	4	271	7	269	3.2e-85	280	COG1464	ABC-type metal ion transport system, periplasmic component/surface antigen	268
2918744801	220	95.95	1	220	10	222	1.2e-85	281.1	COG2011	ABC-type methionine transport system, permease component	222
2918744802	290	70	16	278	1	238	8.2e-106	348.7	COG1135	ABC-type methionine transport system, ATPase component	339
2918744803	270	98.15	1	270	6	270	3.2e-102	335.9	COG1464	ABC-type metal ion transport system, periplasmic component/surface antigen	268
2918744805	300	99.58	63	300	1	238	1.4e-106	349.8	COG1186	Protein chain release factor B	239
2918744806	229	95.48	7	224	1	211	4.6e-51	168.4	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
2918744807	898	98.85	7	890	9	865	0.0e+00	775.8	COG0308	Aminopeptidase N	859
2918744808	337	98.78	5	337	3	326	0.0e+00	466.6	COG0158	Fructose-1,6-bisphosphatase	326
2918744810	317	20.18	12	89	4	69	6.3e-65	15.2	COG0280	Phosphotransacetylase	327
2918744810	317	66.67	81	308	106	323	6.3e-65	200.2	COG0280	Phosphotransacetylase	327
2918744811	1001	98.6	48	943	3	705	3.8e-71	234.3	COG0744	Membrane carboxypeptidase (penicillin-binding protein)	661
2918744812	101	54.84	7	96	49	116	2.2e-03	12.7	COG2363	Uncharacterized membrane protein YgdD, TMEM256/DUF423 family	124
2918744813	187	93.81	5	187	6	187	7.7e-35	115.3	COG1896	5'-deoxynucleotidase YfbR and related HD superfamily hydrolases	193
2918744814	254	96.15	73	245	2	151	4.6e-68	222.2	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
2918744815	330	98.25	1	329	1	281	6.6e-90	296.2	COG1319	CO or xanthine dehydrogenase, FAD-binding subunit	284
2918744816	725	98.93	4	724	4	740	0.0e+00	618	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
2918744817	309	85.11	1	297	18	280	1.1e-48	160.2	COG3386	Sugar lactone lactonase YvrE	307
2918744818	310	99.64	1	307	1	280	3.6e-32	106.3	COG3302	DMSO reductase anchor subunit	281
2918744819	241	92.68	18	237	10	199	4.5e-65	213.4	COG0437	Fe-S-cluster-containing dehydrogenase component	203
2918744820	981	95.93	4	944	33	809	0.0e+00	559.9	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
2918744821	311	97.67	16	309	1	294	2.9e-59	195.8	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918744822	256	97.07	13	252	5	236	7.4e-51	167.4	COG2188	DNA-binding transcriptional regulator, GntR family	236
2918744824	391	98.49	4	391	4	395	2.5e-115	380	COG2721	Altronate dehydratase	381
2918744825	309	92.94	1	309	5	307	7.5e-86	282.5	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
2918744826	333	94.84	1	333	5	335	3.6e-94	310.2	COG2055	Malate/lactate/ureidoglycolate dehydrogenase, LDH2 family	349
2918744827	330	96.87	7	329	10	318	4.2e-84	276.9	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918744828	401	98.99	3	398	3	396	1.0e-126	417.5	COG0282	Acetate kinase	396
2918744829	607	97.84	19	598	1	543	0.0e+00	484.9	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
2918744830	274	97.15	19	262	4	242	1.1e-64	212.3	COG1414	DNA-binding transcriptional regulator, IclR family	246
2918744831	327	90	17	326	4	300	7.2e-46	151.4	COG0714	MoxR-like ATPase	329
2918744832	583	35.48	7	246	14	233	5.1e-90	52.4	COG4547	Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide:5, 6-dimethylbenzimidazole phosphorib...	620
2918744832	583	46.61	225	579	312	600	5.1e-90	242.4	COG4547	Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide:5, 6-dimethylbenzimidazole phosphorib...	620
2918744833	270	99.59	3	248	2	246	9.4e-72	235.4	COG1414	DNA-binding transcriptional regulator, IclR family	246
2918744834	330	98.12	10	328	4	316	1.5e-93	307.8	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918744835	479	91.44	3	455	39	476	8.2e-49	160.8	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918744836	507	94.72	4	505	16	553	1.1e-111	368.3	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2918744837	266	96.53	10	261	4	253	2.0e-16	54.2	COG0730	Uncharacterized membrane protein YfcA	258
2918744838	271	97.56	28	271	2	241	1.7e-70	231.3	COG1414	DNA-binding transcriptional regulator, IclR family	246
2918744839	552	98.06	1	546	5	561	0.0e+00	485.2	COG2303	Choline dehydrogenase or related flavoprotein	542
2918744840	438	47.26	236	436	11	191	1.8e-36	30.2	COG0477	MFS family permease	338
2918744840	438	62.92	9	271	4	244	1.8e-36	94.5	COG0477	MFS family permease	338
2918744841	131	81.25	57	129	14	78	5.8e-22	71	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2918744842	74	59.32	1	52	12	46	4.6e-06	21.6	COG5466	Predicted small metal-binding protein	59
2918744843	167	95.51	1	153	4	152	5.3e-61	199.4	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
2918744844	749	94.63	14	730	36	740	3.5e-121	400.6	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
2918744845	434	22.56	5	79	51	87	1.6e-33	9	COG2010	Cytochrome c, mono- and diheme variants	150
2918744845	434	74.39	298	433	34	155	1.6e-33	43.5	COG2010	Cytochrome c, mono- and diheme variants	150
2918744845	434	99.39	123	297	1	163	1.6e-33	63.1	COG2010	Cytochrome c, mono- and diheme variants	150
2918744846	338	97.67	2	296	3	296	7.3e-67	220.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918744847	282	94.57	21	282	12	255	7.3e-85	279	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2918744848	262	98.84	1	262	1	256	9.2e-108	354.3	COG4525	ABC-type taurine transport system, ATPase component	259
2918744849	339	98.2	1	338	5	332	1.9e-116	383.5	COG4521	ABC-type taurine transport system, periplasmic component	334
2918744850	506	98.68	20	498	4	453	1.5e-114	377.6	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
2918744851	141	67.88	7	123	13	105	9.6e-10	33	COG4319	Ketosteroid isomerase homolog	137
2918744852	482	96.91	62	451	4	379	2.2e-63	209.2	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918744853	532	95.16	2	530	17	566	4.1e-96	317.6	COG0747	ABC-type transport system, periplasmic component	556
2918744854	324	99.06	3	324	2	316	1.7e-113	373.9	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2918744855	303	95.3	14	303	14	297	7.1e-97	318.5	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2918744856	349	95.38	7	337	1	310	0.0e+00	434.9	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
2918744857	345	97.19	7	322	3	313	5.6e-107	352.2	COG4608	ABC-type oligopeptide transport system, ATPase component	309
2918744858	558	97.2	1	556	11	530	2.7e-98	324.2	COG1574	Predicted amidohydrolase YtcJ	535
2918744859	314	95.09	1	311	1	310	1.9e-64	212.7	COG0523	GTPase, G3E family	323
2918744860	153	83.95	13	151	19	154	5.7e-14	47.1	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2918744863	219	92.12	4	198	16	202	1.4e-54	179.1	COG5514	Uncharacterized protein	203
2918744864	436	97.26	1	435	7	432	2.3e-115	380.3	COG1253	Hemolysin or related protein, contains CBS domains	429
2918744865	283	86.71	69	263	17	153	1.2e-13	46.2	COG0639	Diadenosine tetraphosphatase ApaH/serine/threonine protein phosphatase, PP2A family	155
2918744866	238	91.44	25	208	15	185	2.7e-32	106.9	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
2918744867	491	98.68	22	490	3	452	1.2e-125	414.5	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
2918744868	791	95.67	2	596	14	566	0.0e+00	568.3	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
2918744874	321	95.22	6	320	4	322	9.9e-57	187.2	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918744875	389	70.12	84	232	30	144	6.4e-20	65.2	COG2010	Cytochrome c, mono- and diheme variants	150
2918744876	265	96.41	16	264	4	245	2.4e-92	303.6	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2918744877	360	94.57	102	357	12	255	2.4e-50	166.2	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2918744878	337	82.39	9	322	9	284	2.0e-41	136.8	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918744879	274	92.86	36	254	4	211	2.2e-50	165.8	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
2918744880	369	95.63	11	362	13	340	9.8e-74	243	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2918744881	330	95.52	6	329	5	324	7.7e-43	141.3	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918744882	410	94.74	10	408	18	395	5.9e-61	201.1	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918744883	326	95.82	7	326	5	325	1.6e-39	130.7	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918744884	206	94.76	2	195	10	190	3.7e-57	188	COG5553	Predicted metal-dependent enzyme of the double-stranded beta helix superfamily	191
2918744885	541	75.44	266	361	10	95	8.2e-46	23	COG0607	Rhodanese-related sulfurtransferase	110
2918744885	541	86.84	7	112	11	109	8.2e-46	46.1	COG0607	Rhodanese-related sulfurtransferase	110
2918744885	541	87.72	130	236	8	107	8.2e-46	48.3	COG0607	Rhodanese-related sulfurtransferase	110
2918744885	541	94.74	380	491	6	113	8.2e-46	28.3	COG0607	Rhodanese-related sulfurtransferase	110
2918744887	486	81.92	1	484	28	453	0.0e+00	503.3	COG0513	Superfamily II DNA and RNA helicase	513
2918744888	296	98.99	1	296	1	293	1.2e-113	373.9	COG2321	Predicted metalloprotease	295
2918744889	188	97.84	2	188	2	182	6.8e-68	222.7	COG0717	Deoxycytidine triphosphate deaminase	183
2918744890	428	91.98	1	425	23	412	1.1e-97	321.8	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
2918744891	327	54.96	2	247	36	229	4.4e-08	26.8	COG4257	Streptogramin lyase	353
2918744892	201	74.63	1	197	7	206	1.2e-18	60.4	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918744893	293	97.67	2	293	2	295	8.6e-65	214.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918744894	366	94.62	2	341	6	339	3.4e-82	270.7	COG1744	Basic membrane lipoprotein Med, periplasmic binding protein (PBP1-ABC) superfamily	345
2918744895	843	49.55	6	407	13	398	1.6e-65	167.2	COG2366	Acyl-homoserine lactone (AHL) acylase PvdQ	768
2918744895	843	56.87	397	842	327	769	1.6e-65	54.9	COG2366	Acyl-homoserine lactone (AHL) acylase PvdQ	768
2918744896	268	82.58	121	262	12	120	2.8e-18	60.4	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918744897	314	98.67	6	312	1	297	4.9e-43	142.6	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918744898	432	48.3	227	430	10	194	4.7e-16	13.1	COG0477	MFS family permease	338
2918744898	432	80.42	12	276	10	317	4.7e-16	43.6	COG0477	MFS family permease	338
2918744899	353	96.82	20	352	6	340	1.2e-110	364.2	COG1816	Adenosine deaminase	345
2918744900	104	89.09	1	104	9	106	1.5e-27	90.6	COG4654	Cytochrome c551/c552	110
2918744901	300	98.01	9	300	1	295	1.0e-35	118.6	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918744902	337	99.4	3	337	3	331	2.6e-79	261.5	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2918744903	394	50	41	392	283	605	2.9e-12	36.4	COG3408	Glycogen debranching enzyme (alpha-1,6-glucosidase)	641
2918744904	332	95.69	9	332	7	317	7.0e-84	276.1	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
2918744905	378	19.9	264	332	130	168	2.8e-18	4.4	COG0693	Putative intracellular protease/amidase	188
2918744905	378	95.41	34	231	7	193	2.8e-18	57.4	COG0693	Putative intracellular protease/amidase	188
2918744906	320	96.87	3	318	8	316	3.1e-95	313.4	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918744907	290	99.29	14	290	2	279	2.6e-47	156.3	COG3618	Predicted metal-dependent hydrolase, TIM-barrel fold	279
2918744908	397	94.51	12	396	6	384	1.3e-103	341.5	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2918744909	330	98.75	9	329	3	317	3.2e-79	260.9	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918744910	289	97.19	3	285	2	278	1.6e-78	258.3	COG2301	Citrate lyase beta subunit	283
2918744911	298	96.35	1	290	1	290	4.5e-61	201.8	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918744912	390	98.3	5	368	3	349	1.3e-88	291.8	COG1744	Basic membrane lipoprotein Med, periplasmic binding protein (PBP1-ABC) superfamily	345
2918744913	306	97.04	1	306	7	301	3.8e-98	322.8	COG1079	ABC-type uncharacterized transport system, permease component	304
2918744914	383	97.21	3	360	6	353	4.3e-105	345.6	COG4603	ABC-type uncharacterized transport system, permease component	356
2918744915	509	99.4	2	495	4	501	0.0e+00	578.2	COG3845	ABC-type uncharacterized transport system, ATPase component	501
2918744916	459	98.87	25	457	4	441	0.0e+00	568.8	COG2252	Xanthine/uracil/vitamin C permease, AzgA family	436
2918744917	327	99.34	10	310	1	299	4.1e-48	159.3	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918744918	816	98.21	26	816	10	776	0.0e+00	1203	COG4631	Xanthine dehydrogenase, molybdopterin-binding subunit B	781
2918744919	535	97.16	6	520	5	483	0.0e+00	618.2	COG4630	Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A	493
2918744920	417	96.19	1	417	11	414	2.0e-78	258.6	COG1914	Mn2+ and Fe2+ transporters of the NRAMP family	416
2918744921	305	99	9	305	1	298	7.5e-52	171.6	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918744922	719	99.07	7	707	4	641	0.0e+00	557.6	COG4231	TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit	640
2918744923	540	93.63	4	223	3	193	2.2e-19	63.7	COG1014	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, gamma subunit	203
2918744924	329	97.18	8	328	8	317	3.9e-85	280.4	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918744925	144	94.96	3	144	4	135	1.3e-25	84.7	COG0824	Acyl-CoA thioesterase FadM	137
2918744928	916	93.17	44	913	50	949	0.0e+00	701.5	COG0474	Magnesium-transporting ATPase (P-type)	917
2918744929	480	98.75	8	479	2	474	0.0e+00	551.9	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918744930	446	98.82	13	446	5	421	0.0e+00	541.2	COG2379	Glycerate-2-kinase	422
2918744931	401	99.75	1	401	1	407	0.0e+00	471.8	COG3748	Uncharacterized membrane protein	407
2918744932	268	90.03	3	268	9	279	1.9e-60	199.3	COG1975	Xanthine and CO dehydrogenase maturation factor, XdhC/CoxF family	278
2918744934	116	91.94	1	116	11	124	5.1e-45	147.2	COG2351	5-hydroxyisourate hydrolase (purine catabolism), transthyretin-related family	124
2918744935	221	89.22	1	213	15	221	1.4e-59	195.9	COG1802	DNA-binding transcriptional regulator, GntR family	230
2918744936	323	98.13	8	312	3	265	4.2e-47	155.4	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
2918744937	592	92.11	176	589	33	417	4.8e-44	145.4	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
2918744937	592	93.18	1	176	6	169	4.9e-56	183.6	COG3195	2-oxo-4-hydroxy-4-carboxy--5-ureidoimidazoline (OHCU) decarboxylase	176
2918744938	411	97.37	6	411	10	416	2.9e-68	225.4	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
2918744939	303	99.32	18	300	1	293	1.3e-45	151	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918744940	438	97.56	12	429	7	405	2.8e-42	139.3	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
2918744941	297	97.88	1	276	1	277	3.4e-52	172	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918744942	307	96.68	2	295	1	291	1.5e-50	167.3	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918744943	156	30.15	6	150	336	480	1.6e-17	57.6	COG2940	SET domain-containing protein (function unknown)	480
2918744944	497	92.83	13	497	23	488	0.0e+00	502.7	COG1953	Cytosine/uracil/thiamine/allantoin permease	497
2918744945	245	99.57	1	229	2	230	1.6e-81	267.7	COG4126	Asp/Glu/hydantoin racemase	230
2918744946	251	93.1	14	242	6	221	2.4e-52	172.2	COG1802	DNA-binding transcriptional regulator, GntR family	230
2918744947	231	91.87	1	221	11	202	2.2e-26	88.5	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918744948	329	93.77	1	319	18	318	2.0e-35	117	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2918744949	420	21.52	165	393	95	145	6.6e-07	19.1	COG0412	Dienelactone hydrolase	236
2918744950	496	97.15	1	494	7	449	0.0e+00	535.1	COG2233	Xanthine/uracil permease	451
2918744951	285	93.97	1	284	5	269	5.9e-81	266	COG0656	Aldo/keto reductase, related to diketogulonate reductase	280
2918744952	726	98.68	17	725	6	601	0.0e+00	481.4	COG4191	Signal transduction histidine kinase regulating C4-dicarboxylate transport system	603
2918744953	204	91.09	3	202	7	190	1.8e-60	198.3	COG4566	Two-component response regulator, FixJ family, consists of REC and HTH domains	202
2918744954	450	46.48	253	447	9	186	9.5e-38	27.7	COG0477	MFS family permease	338
2918744954	450	74.93	34	295	4	290	9.5e-38	105	COG0477	MFS family permease	338
2918744956	445	84.16	42	438	21	445	5.3e-58	191.4	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
2918744957	444	97.37	1	424	4	410	0.0e+00	458.7	COG1301	Na+/H+-dicarboxylate symporter	415
2918744958	234	87.5	2	217	21	223	4.1e-53	174.7	COG1802	DNA-binding transcriptional regulator, GntR family	230
2918744959	360	94.72	1	358	12	352	9.2e-72	236.6	COG0628	Predicted PurR-regulated permease PerM	355
2918744960	143	89.4	4	143	14	148	4.1e-31	102.4	COG4704	Uncharacterized conserved protein, DUF2141 family	151
2918744961	499	95.71	26	499	19	487	0.0e+00	439.1	COG3670	Carotenoid cleavage dioxygenase or a related enzyme	490
2918744962	300	98.01	2	298	3	297	1.3e-70	233.2	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918744963	597	99.32	1	596	1	588	0.0e+00	1177.7	COG3960	Glyoxylate carboligase	592
2918744964	259	98.46	1	259	1	256	1.8e-120	396.1	COG3622	Hydroxypyruvate isomerase	260
2918744965	302	100	5	292	1	286	1.8e-105	346.9	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
2918744966	444	81.08	8	396	3	332	4.6e-39	129.1	COG0644	Dehydrogenase (flavoprotein)	396
2918744967	767	96.61	2	440	14	440	0.0e+00	556.2	COG0281	Malic enzyme	432
2918744967	767	99.39	437	765	1	325	3.1e-107	352.7	COG0280	Phosphotransacetylase	327
2918744968	204	84.75	12	202	9	158	1.4e-26	81.9	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
2918744969	421	98.94	45	421	1	375	2.1e-123	406.3	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
2918744970	333	93.37	5	329	8	317	7.3e-76	250	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
2918744971	344	85.07	1	337	10	294	7.2e-29	95.7	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918744972	286	94.82	11	272	3	240	1.2e-83	275.1	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2918744973	256	96.51	1	253	7	255	7.4e-72	236.5	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2918744974	160	93.46	1	156	5	147	3.8e-28	93.1	COG0590	tRNA(Arg) A34 adenosine deaminase TadA	152
2918744977	298	97.59	4	293	3	286	1.5e-116	383.1	COG3555	Aspartyl/asparaginyl beta-hydroxylase, cupin superfamily	291
2918744978	132	94.89	1	132	2	131	1.0e-25	84.9	COG1765	Uncharacterized OsmC-related protein	137
2918744979	155	94.3	1	152	4	152	2.0e-45	149.3	COG1522	DNA-binding transcriptional regulator, Lrp family	154
2918744980	433	97.94	1	423	5	384	1.8e-92	305.1	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918744981	360	88.03	3	344	21	351	2.1e-37	123.5	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
2918744982	342	76.42	1	312	4	259	1.8e-24	81.3	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918744983	174	95.42	13	174	4	149	2.5e-34	113.2	COG0590	tRNA(Arg) A34 adenosine deaminase TadA	152
2918744984	276	98.16	1	274	6	272	1.2e-47	157.4	COG0829	Urease accessory protein UreH	269
2918744985	292	98.34	4	288	1	296	3.7e-52	172.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918744986	196	64.92	8	185	38	161	1.0e-13	46.2	COG5553	Predicted metal-dependent enzyme of the double-stranded beta helix superfamily	191
2918744987	528	85.96	1	106	10	107	1.0e-45	26.3	COG0607	Rhodanese-related sulfurtransferase	110
2918744987	528	85.96	125	232	7	104	1.0e-45	48.5	COG0607	Rhodanese-related sulfurtransferase	110
2918744987	528	85.96	259	358	6	103	1.0e-45	38.4	COG0607	Rhodanese-related sulfurtransferase	110
2918744987	528	92.98	366	468	6	111	1.0e-45	27.8	COG0607	Rhodanese-related sulfurtransferase	110
2918744988	336	96.24	10	335	10	316	3.6e-91	300.2	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918744989	400	98.49	6	398	5	395	4.7e-117	385.7	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
2918744990	278	69.52	82	258	42	187	2.7e-09	23.9	COG2945	Alpha/beta superfamily hydrolase	210
2918744992	139	20.24	22	136	114	180	5.2e-10	33.9	COG0790	TPR repeat	292
2918744993	719	94.93	4	719	34	745	8.3e-122	402.1	COG4774	Outer membrane receptor for monomeric catechols	750
2918744994	68	90.77	7	68	7	65	4.9e-28	91.6	COG2879	Uncharacterized short protein YbdD, DUF466 family	65
2918744995	688	99.18	32	685	1	606	0.0e+00	899	COG1966	Carbon starvation protein CstA	575
2918744997	172	54.22	12	170	115	249	3.6e-40	133.4	COG0791	Cell wall-associated hydrolase, NlpC family	197
2918744998	141	91.67	1	131	9	129	2.7e-55	180.5	COG5649	Uncharacterized protein	132
2918745000	397	79	22	268	16	237	8.5e-21	68.2	COG2339	Membrane proteinase PrsW, cleaves anti-sigma factor RsiW, M82 family	274
2918745001	259	70.67	4	259	88	299	6.6e-55	181.8	COG3921	Uncharacterized conserved protein	300
2918745002	131	13.14	5	131	436	502	2.8e-01	4.6	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
2918745004	521	78.96	163	519	69	387	4.4e-36	119.8	COG1680	CubicO group peptidase, beta-lactamase class C family	390
2918745005	208	54.84	2	206	43	195	8.7e-06	20.9	COG0500	SAM-dependent methyltransferase	257
2918745006	214	98.1	8	210	2	208	1.9e-63	208.5	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918745007	456	97.6	1	454	1	448	0.0e+00	569.1	COG4564	Signal transduction histidine kinase	459
2918745009	312	89.9	1	200	17	203	6.0e-39	128.2	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
2918745009	312	92.98	201	311	5	110	9.3e-10	32.7	COG0607	Rhodanese-related sulfurtransferase	110
2918745010	336	97.81	3	333	3	315	6.0e-102	335.4	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
2918745011	513	99.23	1	511	1	518	0.0e+00	465.1	COG3540	Phosphodiesterase/alkaline phosphatase D	522
2918745012	256	95.94	1	256	10	269	1.2e-39	131.2	COG0584	Glycerophosphoryl diester phosphodiesterase	257
2918745013	306	95.05	2	306	11	279	1.8e-78	258.3	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
2918745014	303	96.31	10	301	7	293	1.1e-71	236.1	COG1175	ABC-type sugar transport system, permease component	295
2918745015	442	98.87	1	435	5	442	2.6e-61	202.9	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
2918745016	450	92.16	13	433	8	336	7.9e-50	163.8	COG0371	Glycerol dehydrogenase or related enzyme, iron-containing ADH family	360
2918745017	320	96.25	1	314	10	317	8.0e-89	292.4	COG2390	DNA-binding transcriptional regulator LsrR, DeoR family	321
2918745018	424	96.46	19	408	12	392	1.2e-113	374.1	COG2814	Predicted arabinose efflux permease, MFS family	394
2918745019	230	94.94	1	229	3	227	2.9e-87	286.4	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2918745020	292	96.48	40	292	7	253	2.8e-120	395	COG4674	ABC-type uncharacterized transport system, ATPase component	249
2918745021	407	97.83	19	365	6	321	5.3e-90	296.4	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918745022	515	98.01	215	513	6	300	5.1e-97	319.3	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2918745023	422	98.91	12	396	3	364	1.3e-71	236.2	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918745024	486	49.35	279	483	4	192	5.3e-40	22.2	COG0477	MFS family permease	338
2918745024	486	85.38	23	301	4	330	5.3e-40	114.1	COG0477	MFS family permease	338
2918745026	308	85.61	176	307	15	127	3.8e-25	81.4	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918745027	355	84.98	37	345	45	310	2.6e-47	155.8	COG3509	Poly(3-hydroxybutyrate) depolymerase	312
2918745028	293	88.52	2	263	30	268	3.3e-115	378.8	COG2326	Polyphosphate kinase 2, PPK2 family	270
2918745029	345	90.24	30	345	31	326	4.0e-48	158.5	COG0598	Mg2+ and Co2+ transporter CorA	322
2918745030	285	97.67	4	266	2	253	7.1e-72	236.8	COG0613	Predicted metal-dependent phosphoesterase TrpH, contains PHP domain	258
2918745031	325	95.02	32	318	4	289	4.4e-35	115.9	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918745032	211	95.75	2	211	2	204	6.0e-62	203.1	COG0009	tRNA A37 threonylcarbamoyladenosine synthetase subunit TsaC/SUA5/YrdC	211
2918745033	223	85.59	2	219	14	215	2.3e-36	120.1	COG1994	Zn-dependent protease (includes SpoIVFB)	230
2918745034	443	74.58	357	409	5	48	2.2e-05	17.6	COG3422	Uncharacterized conserved protein YegP, UPF0339 family	59
2918745034	443	98.42	5	318	5	316	3.3e-92	303.5	COG0180	Tryptophanyl-tRNA synthetase	314
2918745035	200	99.53	1	198	1	210	2.2e-40	132.6	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918745036	471	79.19	52	462	77	388	5.2e-52	172.2	COG0642	Signal transduction histidine kinase	336
2918745038	443	99.07	1	443	1	427	0.0e+00	584.1	COG0172	Seryl-tRNA synthetase	429
2918745039	133	96.35	1	133	2	133	3.2e-42	138.6	COG2764	Uncharacterized conserved protein PhnB, glyoxalase superfamily	136
2918745040	320	89.31	6	320	13	321	4.5e-78	257.4	COG1171	Threonine dehydratase	347
2918745041	322	97.63	5	297	3	290	2.9e-124	408.4	COG0761	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH	294
2918745042	147	77.97	3	147	3	140	2.0e-32	106.7	COG1047	FKBP-type peptidyl-prolyl cis-trans isomerase 2	174
2918745043	225	100	1	225	1	224	6.7e-82	268.9	COG2003	DNA repair protein RadC, contains a helix-hairpin-helix DNA-binding motif	224
2918745044	218	94.02	7	218	7	179	1.7e-49	162.5	COG2840	DNA-nicking endonuclease, Smr domain	184
2918745045	407	83.02	4	402	1	357	3.0e-64	212.6	COG0446	NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase	415
2918745046	140	90.23	5	139	7	126	2.2e-35	116.1	COG2346	Truncated hemoglobin YjbI	133
2918745047	398	99.5	1	397	1	396	0.0e+00	655.2	COG3007	Trans-2-enoyl-CoA reductase	398
2918745048	275	95.05	1	262	6	274	1.2e-54	180.1	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918745049	231	92.98	3	230	14	225	5.3e-67	220.3	COG0765	ABC-type amino acid transport system, permease component	222
2918745050	240	92.54	4	226	17	227	3.0e-70	231	COG0765	ABC-type amino acid transport system, permease component	222
2918745051	247	99.17	1	240	2	241	1.7e-112	369.1	COG1126	ABC-type polar amino acid transport system, ATPase component	240
2918745052	334	98.77	2	329	3	323	5.1e-101	332.9	COG3491	Isopenicillin N synthase and related dioxygenases	322
2918745053	229	97.29	1	221	1	215	2.0e-53	176.1	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
2918745054	432	47.78	241	431	8	190	3.5e-24	20.4	COG0477	MFS family permease	338
2918745054	432	61.1	18	275	8	241	3.5e-24	61.1	COG0477	MFS family permease	338
2918745055	316	91.34	1	246	22	253	2.6e-79	260.4	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
2918745056	668	99.65	48	617	3	569	0.0e+00	771.7	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
2918745057	221	89.2	15	220	23	212	5.5e-72	236.1	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
2918745058	137	95.54	7	128	6	112	5.7e-43	139.9	COG3125	Heme/copper-type cytochrome/quinol oxidase, subunit 4	111
2918745059	285	93.7	13	264	7	244	5.3e-78	256.2	COG3346	Cytochrome oxidase assembly protein ShyY1	252
2918745060	468	81.47	37	445	70	390	2.4e-31	104.3	COG0642	Signal transduction histidine kinase	336
2918745061	182	97.25	1	182	5	181	2.9e-73	240.3	COG4567	Two-component response regulator, ActR/RegA family, consists of REC and Fis-type HTH domains	182
2918745062	220	90.17	2	218	18	228	3.6e-59	194.2	COG1272	Predicted membrane channel-forming protein YqfA, hemolysin III family	226
2918745063	74	94.44	5	74	5	72	4.2e-13	44.2	COG2900	Uncharacterized coiled-coil protein SlyX (sensitive to lysis X)	72
2918745064	506	90.86	5	334	3	350	1.3e-23	78.9	COG0477	MFS family permease	338
2918745065	298	98.01	2	294	3	297	1.0e-80	266.3	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918745066	493	15.02	4	67	24	58	7.2e-10	11.2	COG3910	Predicted ATPase	233
2918745066	493	22.32	311	438	142	193	7.2e-10	20.1	COG3910	Predicted ATPase	233
2918745067	838	99.28	2	836	6	828	0.0e+00	739.7	COG3127	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component	829
2918745068	286	94.01	8	276	16	266	5.5e-59	194.1	COG1526	Formate dehydrogenase assembly factor FdhD	266
2918745070	401	95.87	162	383	2	210	2.2e-62	204.8	COG2864	Cytochrome b subunit of formate dehydrogenase	218
2918745072	204	72.68	1	191	14	162	6.0e-46	150.8	COG0437	Fe-S-cluster-containing dehydrogenase component	203
2918745073	996	99.75	39	996	2	809	0.0e+00	638.7	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
2918745075	205	89.22	7	202	8	189	1.5e-33	110.3	COG3381	Cytoplasmic chaperone TorD involved in molybdoenzyme TorA maturation	204
2918745076	712	41.13	605	697	41	91	4.9e-28	19.2	COG1145	Ferredoxin	99
2918745076	712	50.81	181	254	39	101	4.9e-28	17.7	COG1145	Ferredoxin	99
2918745076	712	53.23	282	383	39	104	4.9e-28	47	COG1145	Ferredoxin	99
2918745076	712	55.65	549	662	36	104	4.9e-28	38.5	COG1145	Ferredoxin	99
2918745079	265	54	3	240	30	218	7.1e-76	250.3	COG1118	ABC-type sulfate/molybdate transport systems, ATPase component	345
2918745080	250	93.63	1	250	16	265	8.0e-69	226.5	COG0725	ABC-type molybdate transport system, periplasmic component	258
2918745081	227	94.67	8	226	3	215	3.6e-82	269.6	COG4149	ABC-type molybdate transport system, permease component	225
2918745082	115	77.86	3	113	2	103	1.1e-36	120.3	COG2005	DNA-binding transcriptional regulator ModE (molybdenum-dependent)	130
2918745083	957	21.78	11	235	5	217	0.0e+00	163.9	COG3383	Predicted molibdopterin-dependent oxidoreductase YjgC	978
2918745083	957	69.12	231	944	262	937	0.0e+00	691.5	COG3383	Predicted molibdopterin-dependent oxidoreductase YjgC	978
2918745084	610	87.35	36	198	17	161	1.5e-24	80.3	COG1905	NADH:ubiquinone oxidoreductase 24 kD subunit (chain E)	160
2918745084	610	92.69	222	610	24	416	1.7e-119	392	COG1894	NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F)	424
2918745085	314	97.01	3	305	3	294	4.2e-44	146	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918745086	363	95.8	34	313	10	283	1.1e-97	321.1	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
2918745087	397	84.33	1	381	7	275	1.6e-37	123.7	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
2918745088	227	95.35	1	221	6	210	5.8e-64	210.6	COG3132	Uncharacterized conserved protein YceH, UPF0502 family	215
2918745089	238	92.4	1	237	16	246	1.9e-79	260.8	COG3698	Uncharacterized protein YigE, DUF2233 family	250
2918745090	343	97.99	2	343	6	346	9.2e-106	348.3	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
2918745091	696	71.83	574	691	9	110	3.9e-36	117.8	COG0073	tRNA-binding EMAP/Myf domain	123
2918745091	696	98.39	1	564	4	553	0.0e+00	615.6	COG0143	Methionyl-tRNA synthetase	558
2918745092	251	96.6	2	248	10	265	6.3e-51	167.8	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918745094	558	92.72	12	553	14	535	0.0e+00	456.2	COG0659	Sulfate permease or related transporter, MFS superfamily	554
2918745097	278	95.97	42	277	2	239	7.2e-67	220.2	COG1354	Chromatin segregation and condensation protein Rec8/ScpA/Scc1, kleisin family	248
2918745098	523	96.54	1	523	8	509	0.0e+00	690.9	COG0029	Aspartate oxidase	518
2918745099	297	95.15	32	297	6	260	5.3e-97	318.8	COG0413	Ketopantoate hydroxymethyltransferase	268
2918745100	279	99.3	1	276	1	283	5.1e-103	338.5	COG0414	Panthothenate synthetase	285
2918745101	212	99.08	1	212	2	216	3.5e-39	129.1	COG0602	Organic radical activating enzyme	212
2918745102	120	67.11	1	115	1	102	3.4e-24	80.4	COG0720	6-pyruvoyl-tetrahydropterin synthase	127
2918745103	374	95.38	21	356	15	324	1.1e-117	387.3	COG0379	Quinolinate synthase	324
2918745104	292	97.5	12	292	6	278	3.0e-101	332.7	COG0157	Nicotinate-nucleotide pyrophosphorylase	280
2918745105	337	98.78	1	333	2	326	3.3e-105	346.6	COG0240	Glycerol-3-phosphate dehydrogenase	329
2918745106	154	91.08	1	152	6	148	1.3e-55	181.9	COG1952	Preprotein translocase subunit SecB	157
2918745107	86	96.25	2	80	3	79	6.2e-22	72.4	COG0695	Glutaredoxin	80
2918745108	138	88.6	35	138	12	112	3.0e-27	89.7	COG0607	Rhodanese-related sulfurtransferase	110
2918745109	247	99.57	1	230	1	229	7.6e-104	341.1	COG0588	Phosphoglycerate mutase (BPG-dependent)	230
2918745110	481	89.95	19	424	34	400	2.9e-124	409.4	COG0793	C-terminal processing protease CtpA/Prc, contains a PDZ domain	406
2918745111	252	97.32	1	250	4	257	1.6e-88	290.8	COG0476	Molybdopterin or thiamine biosynthesis adenylyltransferase	254
2918745112	670	27.47	7	189	7	192	1.9e-68	63.8	COG2982	Uncharacterized protein involved in outer membrane biogenesis	648
2918745112	670	66.32	162	643	216	664	1.9e-68	162.3	COG2982	Uncharacterized protein involved in outer membrane biogenesis	648
2918745113	137	51.66	5	128	4	112	2.6e-12	41.4	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918745114	210	99.53	2	210	1	210	3.4e-59	194.6	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918745115	447	76.8	5	443	88	375	4.7e-54	176.6	COG4585	Signal transduction histidine kinase	365
2918745116	54	98.15	1	54	1	53	3.1e-21	70.1	COG5487	Uncharacterized membrane protein YtjA, UPF0391 family	54
2918745117	124	95.19	1	118	3	101	2.0e-09	29.7	COG4575	Membrane-anchored ribosome-binding protein, inhibits growth in stationary phase, ElaB/YqjD/DUF883 family	104
2918745120	186	84.71	41	186	6	138	9.0e-37	120.9	COG2193	Bacterioferritin (cytochrome b1)	157
2918745121	166	50.25	19	166	98	196	1.1e-17	57.7	COG2823	Osmotically-inducible protein OsmY, contains BON domain	196
2918745123	293	96.35	1	293	6	295	4.7e-18	60.1	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918745125	237	90.86	41	236	16	194	8.2e-48	156.8	COG0302	GTP cyclohydrolase I	195
2918745126	250	96.5	3	250	6	253	1.1e-53	177.1	COG3568	Metal-dependent hydrolase, endonuclease/exonuclease/phosphatase family	259
2918745127	157	75	4	155	17	145	7.5e-16	53.2	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2918745128	601	99.66	3	597	1	584	0.0e+00	846	COG0173	Aspartyl-tRNA synthetase	585
2918745129	206	88.74	1	205	5	201	1.2e-70	231.9	COG2928	Uncharacterized membrane protein	222
2918745130	110	89.02	1	76	8	80	3.2e-30	98.5	COG2331	Predicted nucleic acid-binding protein, contains Zn-ribbon domain	82
2918745131	479	94.6	1	475	5	477	6.2e-82	270.3	COG0591	Na+/proline symporter	493
2918745132	521	94.14	1	519	15	496	0.0e+00	550.7	COG0661	Predicted unusual protein kinase regulating ubiquinone biosynthesis, AarF/ABC1/UbiB family	517
2918745133	190	67.16	30	173	12	148	6.0e-19	62.8	COG3165	Ubiquinone biosynthesis protein UbiJ, contains SCP2 domain	204
2918745134	336	99.64	32	336	1	280	2.8e-27	88.3	COG4395	Predicted lipid-binding transport protein, Tim44 family	281
2918745135	243	99.58	8	243	1	238	6.4e-88	288.5	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
2918745136	137	96.67	8	126	4	119	6.6e-49	159.4	COG3536	Uncharacterized conserved protein, DUF971 family	120
2918745137	145	94.33	4	136	2	134	4.8e-22	72.9	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
2918745138	1292	14.46	757	872	58	115	2.5e-69	11.9	COG0247	Fe-S oxidoreductase	388
2918745138	1292	99	872	1272	2	398	2.5e-69	216.7	COG0247	Fe-S oxidoreductase	388
2918745138	1292	99.36	152	776	2	467	0.0e+00	543.1	COG0277	FAD/FMN-containing dehydrogenase	459
2918745139	410	99.08	9	337	2	324	3.7e-109	359	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
2918745140	437	98.42	1	432	7	442	6.9e-68	224.6	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
2918745141	293	96.64	2	293	6	293	3.4e-85	280.6	COG1175	ABC-type sugar transport system, permease component	295
2918745142	283	95.05	1	283	11	279	2.4e-83	274.5	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
2918745143	335	99.71	1	329	1	349	0.0e+00	456.6	COG3839	ABC-type sugar transport system, ATPase component	338
2918745144	245	95.94	1	245	6	265	2.6e-45	149.8	COG0584	Glycerophosphoryl diester phosphodiesterase	257
2918745145	812	86.62	37	784	78	815	0.0e+00	451.3	COG3264	Small-conductance mechanosensitive channel	835
2918745146	382	99.17	1	363	2	361	1.6e-126	416.9	COG1377	Flagellar biosynthesis protein FlhB	363
2918745147	697	98.28	3	696	11	695	0.0e+00	958.5	COG1298	Flagellar biosynthesis pathway, component FlhA	696
2918745148	784	13.29	9	72	4	58	2.4e-102	27	COG1419	Flagellar biosynthesis GTPase FlhF	407
2918745148	784	66.43	79	395	132	406	2.4e-102	307.8	COG1419	Flagellar biosynthesis GTPase FlhF	407
2918745149	298	32.33	20	112	3	88	1.3e-16	14.5	COG0455	MinD-like ATPase involved in chromosome partitioning or flagellar assembly	262
2918745149	298	50.75	116	270	117	251	1.3e-16	39.3	COG0455	MinD-like ATPase involved in chromosome partitioning or flagellar assembly	262
2918745150	243	89.68	2	242	25	250	1.4e-67	222.4	COG1191	DNA-directed RNA polymerase specialized sigma subunit	247
2918745151	157	99.32	4	141	2	146	2.2e-11	39.8	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2918745152	198	97.31	6	193	4	184	3.6e-51	167.7	COG3575	Uncharacterized protein	184
2918745153	218	95.85	1	218	10	217	2.6e-86	283.5	COG3143	Chemotaxis regulator CheZ, phosphatase of CheY~P	217
2918745154	132	94.74	3	130	6	131	8.5e-31	101.1	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918745155	360	99.15	3	357	1	349	0.0e+00	465.2	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
2918745156	213	94.51	26	190	5	159	3.2e-55	180.6	COG1871	Chemotaxis receptor (MCP) glutamine deamidase CheD	164
2918745157	273	98.15	9	271	2	266	1.9e-84	277.7	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
2918745158	437	98.28	29	434	4	403	3.8e-38	125.3	COG3434	c-di-GMP-related signal transduction protein, contains EAL and HDOD domains	407
2918745159	685	19.5	1	186	5	151	0.0e+00	105.2	COG0643	Chemotaxis protein histidine kinase CheA	716
2918745159	685	65.25	169	674	256	747	0.0e+00	590.1	COG0643	Chemotaxis protein histidine kinase CheA	716
2918745160	315	96.3	5	264	9	268	5.5e-60	197.8	COG1360	Flagellar motor protein MotB	244
2918745161	286	97.75	1	285	5	265	1.4e-92	304.1	COG1291	Flagellar motor component MotA	266
2918745164	97	90.22	1	92	6	88	1.3e-25	84.2	COG2257	Type III secretion system substrate exporter, FlhB-like	92
2918745167	140	87.88	6	139	6	121	2.5e-32	106.1	COG1516	Flagellin-specific chaperone FliS	132
2918745168	482	99.6	1	480	3	498	9.4e-123	405.4	COG1345	Flagellar capping protein FliD	483
2918745169	115	60	17	115	47	118	2.0e-18	61.6	COG1334	Uncharacterized conserved protein, FlaG/YvyC family	120
2918745170	412	100	3	412	1	388	1.0e-111	368.7	COG1344	Flagellin and related hook-associated protein FlgL	360
2918745171	105	96.23	1	104	3	104	2.0e-28	93.5	COG1677	Flagellar hook-basal body complex protein FliE	105
2918745172	559	97.08	14	559	15	546	0.0e+00	568.6	COG1766	Flagellar biosynthesis/type III secretory pathway M-ring protein FliF/YscJ	545
2918745173	318	93.53	1	318	23	340	1.4e-104	344.7	COG1536	Flagellar motor switch protein FliG	339
2918745174	247	91.77	21	245	15	237	3.2e-38	126.1	COG1317	Flagellar biosynthesis/type III secretory pathway protein FliH	234
2918745175	478	98.87	16	477	4	440	0.0e+00	627.6	COG1157	Flagellar biosynthesis/type III secretory pathway ATPase	441
2918745176	151	99.32	1	148	1	147	6.6e-32	105.2	COG2882	Flagellar biosynthesis chaperone FliJ	148
2918745177	454	77.85	6	439	83	423	6.5e-30	97.3	COG3144	Flagellar hook-length control protein FliK	417
2918745178	141	85.53	1	141	24	159	1.6e-26	87.6	COG1580	Flagellar basal body-associated protein FliL	159
2918745179	333	97	1	331	3	325	3.4e-106	349.5	COG1868	Flagellar motor switch protein FliM	332
2918745180	155	85.11	2	142	22	141	2.3e-35	116.9	COG1886	Flagellar motor switch/type III secretory pathway protein FliN	136
2918745181	161	71.43	22	157	7	106	1.6e-26	87.5	COG3190	Flagellar biogenesis protein FliO	137
2918745182	253	95.58	2	252	11	248	1.7e-101	333.4	COG1338	Flagellar biosynthetic protein FliP	248
2918745183	89	98.88	1	89	1	88	1.1e-37	122.7	COG1987	Flagellar biosynthesis protein FliQ	89
2918745184	264	98.45	5	263	3	256	7.9e-74	242.9	COG1684	Flagellar biosynthesis protein FliR	258
2918745185	402	99.23	1	402	1	385	2.9e-48	159.7	COG1344	Flagellin and related hook-associated protein FlgL	360
2918745186	652	99.32	1	652	5	588	0.0e+00	436.1	COG1256	Flagellar hook-associated protein FlgK	552
2918745187	519	81.65	90	517	78	424	2.3e-113	374.3	COG0840	Methyl-accepting chemotaxis protein	408
2918745188	544	91.76	36	514	36	425	7.5e-116	382.4	COG0840	Methyl-accepting chemotaxis protein	408
2918745189	680	81.88	197	653	78	425	3.7e-115	380.4	COG0840	Methyl-accepting chemotaxis protein	408
2918745190	132	8.98	2	107	238	313	4.9e-05	16.5	COG1511	Uncharacterized membrane protein YhgE, phage infection protein (PIP) family	780
2918745191	31	7.36	1	30	365	393	1.2e-11	38.7	COG0050	Translation elongation factor EF-Tu, a GTPase	394
2918745192	104	98.08	2	104	2	103	2.0e-44	144.6	COG0051	Ribosomal protein S10	104
2918745195	218	96.92	1	215	4	223	1.8e-70	231.8	COG0087	Ribosomal protein L3	218
2918745196	206	97.7	1	206	2	213	2.1e-66	218	COG0088	Ribosomal protein L4	214
2918745197	111	96.81	18	110	2	92	2.4e-31	102.8	COG0089	Ribosomal protein L23	94
2918745198	274	100	1	274	1	275	1.5e-119	393	COG0090	Ribosomal protein L2	275
2918745199	92	98.92	1	92	1	92	6.2e-43	139.4	COG0185	Ribosomal protein S19	93
2918745200	110	89.93	1	110	11	144	1.5e-40	133.2	COG0091	Ribosomal protein L22	120
2918745201	308	87.55	12	240	1	204	4.0e-96	315.3	COG0092	Ribosomal protein S3	233
2918745202	138	93.29	1	137	2	140	3.8e-57	186.8	COG0197	Ribosomal protein L16/L10AE	146
2918745203	83	91.18	13	81	5	66	1.3e-19	64.4	COG0255	Ribosomal protein L29	69
2918745204	89	95.4	2	88	4	86	5.6e-34	110.7	COG0186	Ribosomal protein S17	87
2918745205	168	98.8	1	166	2	165	1.2e-61	201.7	COG0678	Peroxiredoxin	165
2918745206	195	60.32	25	195	66	179	7.4e-16	53.4	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
2918745207	237	94.27	12	204	5	185	8.9e-39	127.2	COG3658	Cytochrome b	192
2918745208	148	97.96	1	148	2	145	2.9e-30	100.1	COG3909	Cytochrome c556	147
2918745209	165	91.08	23	165	10	152	1.6e-13	45.2	COG1225	Peroxiredoxin	157
2918745211	415	98.17	12	408	3	378	4.7e-19	61.6	COG0477	MFS family permease	338
2918745212	151	96.5	1	144	1	138	3.7e-28	92.7	COG2893	Phosphotransferase system, mannose/fructose-specific component IIA	143
2918745213	84	93.26	1	83	6	88	3.8e-28	92.1	COG1925	Phosphotransferase system, HPr and related phosphotransfer proteins	88
2918745214	597	96.86	3	595	3	558	0.0e+00	621	COG1080	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria)	574
2918745216	155	87.5	3	155	5	144	2.4e-05	18.5	COG3678	Periplasmic protein refolding chaperone Spy/CpxP family	160
2918745219	230	98.28	2	226	2	229	3.0e-79	260.2	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918745220	466	83.76	80	466	56	385	6.5e-52	171.9	COG0642	Signal transduction histidine kinase	336
2918745221	347	98.24	1	346	6	339	4.0e-128	421.7	COG2130	NADPH-dependent curcumin reductase CurA	340
2918745223	280	94.35	1	280	10	293	1.4e-33	111.2	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918745224	234	71.21	86	232	20	113	4.7e-15	50	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918745225	378	85.61	21	375	29	391	2.6e-29	94.6	COG1055	Na+/H+ antiporter NhaD or related arsenite permease	424
2918745226	520	97.18	7	520	6	557	1.2e-105	348.6	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2918745227	301	97.67	3	289	2	295	1.1e-52	174.2	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918745228	523	73.63	7	297	4	285	2.6e-34	113.8	COG0477	MFS family permease	338
2918745229	327	97.71	22	327	4	302	0.0e+00	462	COG0320	Lipoate synthase	306
2918745230	226	89.33	1	226	12	212	7.1e-71	232.7	COG0321	Lipoate-protein ligase B	221
2918745231	104	94.44	8	104	6	90	4.5e-29	95.3	COG2921	Putative lipoic acid-binding regulatory protein	90
2918745232	297	97.19	10	289	4	280	9.1e-53	174.4	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
2918745233	161	80.47	41	155	19	121	3.2e-07	25	COG3312	FoF1-type ATP synthase assembly protein I	128
2918745234	269	90.48	2	269	25	252	1.6e-77	254.8	COG0356	FoF1-type ATP synthase, membrane subunit a	246
2918745235	87	90	1	77	8	79	1.2e-21	71.3	COG0636	FoF1-type ATP synthase, membrane subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K	79
2918745236	146	90.68	1	146	13	158	9.0e-39	127.3	COG0711	FoF1-type ATP synthase, membrane subunit b or b'	161
2918745237	176	99.44	1	175	1	177	6.6e-42	138	COG0712	FoF1-type ATP synthase, delta subunit	178
2918745238	517	99.21	1	517	1	500	0.0e+00	784	COG0056	FoF1-type ATP synthase, alpha subunit	504
2918745239	291	99.31	5	289	1	286	2.8e-108	356.6	COG0224	FoF1-type ATP synthase, gamma subunit	287
2918745240	129	23.92	4	128	75	168	9.6e-02	6.7	COG2948	Type IV secretory pathway, VirB10 components	360
2918745241	466	99.36	1	466	1	465	0.0e+00	778.6	COG0055	FoF1-type ATP synthase, beta subunit	468
2918745242	139	97.78	1	135	1	132	4.4e-44	144.2	COG0355	FoF1-type ATP synthase, epsilon subunit	135
2918745243	400	96.45	74	397	8	306	2.9e-69	228.1	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
2918745244	512	98.8	5	505	6	500	0.0e+00	583.4	COG1129	ABC-type sugar transport system, ATPase component	500
2918745245	333	96.24	14	333	6	312	3.1e-90	296.9	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
2918745246	320	96.33	1	320	10	324	1.6e-62	206	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
2918745247	387	97.15	6	385	3	343	7.1e-64	210.9	COG0673	Predicted dehydrogenase	342
2918745248	235	73.71	17	228	37	207	1.9e-08	29	COG0671	Membrane-associated phospholipid phosphatase	232
2918745251	258	96.12	2	258	8	255	9.4e-65	213.2	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2918745252	277	97.61	27	276	3	247	6.3e-70	230	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2918745253	335	89.85	10	335	6	306	9.5e-24	78.7	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918745254	181	97.95	10	134	2	144	3.1e-10	35.7	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2918745255	404	88.3	1	375	3	349	5.4e-34	112.7	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2918745257	301	98.01	3	301	4	298	8.4e-48	158.3	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918745258	381	94.05	8	343	17	427	3.6e-36	116.5	COG1236	RNA processing exonuclease, beta-lactamase fold, Cft2 family	427
2918745259	551	96.95	58	549	14	490	1.1e-78	259.6	COG1793	ATP-dependent DNA ligase	444
2918745260	887	97.23	13	855	8	848	0.0e+00	556.9	COG1201	Lhr-like helicase	814
2918745261	149	78	7	148	28	144	1.5e-19	64	COG0526	Thiol-disulfide isomerase or thioredoxin	127
2918745262	208	76.15	2	198	14	195	1.8e-34	113.5	COG1407	Metallophosphoesterase superfamily enzyme	235
2918745263	174	69.95	5	174	64	212	4.9e-34	111.1	COG3762	Uncharacterized membrane protein	213
2918745264	310	97.84	6	310	7	278	5.2e-66	214.6	COG1512	Uncharacterized membrane protein YgcG, contains a TPM-fold domain	271
2918745265	200	98.38	1	193	3	184	2.2e-69	227.2	COG1704	Uncharacterized conserved protein	185
2918745267	272	92.13	6	268	12	257	2.1e-78	257.7	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
2918745268	297	93.4	9	295	10	278	7.2e-77	253	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
2918745269	371	98.02	13	369	4	349	1.6e-119	393.9	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
2918745270	348	88.36	1	347	2	335	3.2e-40	132.8	COG0687	Spermidine/putrescine-binding periplasmic protein	363
2918745271	324	96.92	1	324	4	318	9.2e-83	272.9	COG3491	Isopenicillin N synthase and related dioxygenases	322
2918745272	234	98.06	21	224	1	202	1.9e-30	100.8	COG1335	Nicotinamidase-related amidase	205
2918745273	310	98.03	1	308	6	303	5.1e-79	259.9	COG1079	ABC-type uncharacterized transport system, permease component	304
2918745274	383	96.09	33	382	6	349	4.6e-83	273.2	COG4603	ABC-type uncharacterized transport system, permease component	356
2918745275	510	99.6	1	508	2	500	0.0e+00	513.9	COG3845	ABC-type uncharacterized transport system, ATPase component	501
2918745276	369	93.77	8	347	7	337	8.5e-66	216.7	COG1744	Basic membrane lipoprotein Med, periplasmic binding protein (PBP1-ABC) superfamily	345
2918745277	128	13.14	4	43	14	31	2.3e-07	5.2	COG2764	Uncharacterized conserved protein PhnB, glyoxalase superfamily	136
2918745277	128	40.88	50	127	75	130	2.3e-07	18.9	COG2764	Uncharacterized conserved protein PhnB, glyoxalase superfamily	136
2918745278	334	94.77	2	331	5	312	3.0e-75	248	COG3491	Isopenicillin N synthase and related dioxygenases	322
2918745279	240	89.47	22	239	11	197	4.8e-27	90.5	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918745280	181	87.03	11	179	10	170	1.4e-46	152.9	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
2918745281	197	97.22	7	197	4	213	1.3e-30	101.6	COG0778	Nitroreductase	207
2918745282	266	96.27	1	259	11	294	2.3e-42	140.2	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918745283	130	89.71	2	128	13	134	1.3e-29	97.4	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
2918745284	252	97.57	39	250	3	203	1.9e-51	169.3	COG1335	Nicotinamidase-related amidase	205
2918745285	370	94.75	6	357	17	341	2.5e-74	245.1	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2918745286	150	91.24	11	140	10	134	2.2e-13	44.7	COG4319	Ketosteroid isomerase homolog	137
2918745287	351	87.93	3	342	15	320	2.1e-84	277.7	COG0429	Predicted hydrolase of the alpha/beta-hydrolase fold	345
2918745289	202	65.87	54	173	42	124	3.8e-26	86.7	COG3245	Cytochrome c5	126
2918745290	474	97.83	13	472	1	450	1.1e-130	431.1	COG1538	Outer membrane protein TolC	457
2918745291	1054	99.8	1	1027	2	1013	0.0e+00	1197.9	COG0841	Multidrug efflux pump subunit AcrB	1009
2918745292	429	95.9	7	394	5	378	3.3e-78	257.9	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918745293	223	84.21	1	214	7	182	1.1e-25	86.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918745296	312	78.99	21	158	26	134	3.3e-01	5.4	COG3105	Uncharacterized membrane-anchored protein YhcB, DUF1043 family	138
2918745301	326	55.77	1	75	29	86	7.8e-08	26	COG3093	Plasmid maintenance system antidote protein VapI, contains XRE-type HTH domain	104
2918745304	80	43.08	13	80	6	61	4.6e-11	38.4	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918745307	308	94.52	16	306	7	282	2.1e-54	179.5	COG0384	Predicted epimerase YddE/YHI9, PhzF superfamily	291
2918745308	331	97.49	9	329	6	316	1.3e-85	281.8	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918745309	257	64.39	117	254	26	110	7.2e-11	36.2	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918745310	217	98.06	14	210	3	204	2.5e-17	53.7	COG1335	Nicotinamidase-related amidase	205
2918745311	94	95.7	1	93	1	89	5.4e-33	107.7	COG4317	Xanthosine utilization system component, XapX domain	93
2918745312	629	99.07	4	541	4	533	0.0e+00	592	COG1574	Predicted amidohydrolase YtcJ	535
2918745313	145	78.47	8	137	16	128	4.5e-22	73.5	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
2918745314	524	48.83	219	453	9	195	5.6e-21	13.4	COG0477	MFS family permease	338
2918745314	524	63.19	9	250	4	245	5.6e-21	59.5	COG0477	MFS family permease	338
2918745315	273	97.63	1	273	6	293	1.4e-48	160.7	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918745317	171	91.91	9	161	11	135	1.7e-12	41.9	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
2918745318	303	77.27	182	303	24	125	8.9e-32	103.4	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918745319	200	80.6	1	193	39	225	6.4e-44	144.6	COG1802	DNA-binding transcriptional regulator, GntR family	230
2918745320	312	93.71	25	292	1	268	3.4e-30	99.6	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
2918745321	212	96.23	1	207	8	211	9.1e-61	199.7	COG0684	Regulator of RNase E activity RraA	210
2918745322	324	98.12	1	322	4	316	5.1e-84	276.6	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918745323	317	95.61	1	316	6	310	3.1e-72	237.9	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918745324	302	99.29	27	295	2	279	3.8e-51	168.9	COG3618	Predicted metal-dependent hydrolase, TIM-barrel fold	279
2918745325	154	97.95	1	147	1	143	4.8e-53	173.3	COG0757	3-dehydroquinate dehydratase	146
2918745326	273	96.13	1	272	6	278	1.3e-77	255.1	COG0169	Shikimate 5-dehydrogenase	283
2918745327	407	98.5	1	404	6	400	7.4e-124	408.3	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2918745328	151	90.57	1	151	15	158	6.2e-34	111.2	COG2030	Acyl dehydratase	159
2918745329	128	97.26	9	112	4	145	6.1e-06	20.1	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2918745330	309	99.03	1	309	1	306	2.0e-78	258.3	COG1893	Ketopantoate reductase	307
2918745331	320	98.34	14	311	3	298	3.5e-48	159.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918745332	652	89.07	208	647	41	374	1.7e-36	119	COG4585	Signal transduction histidine kinase	365
2918745333	220	98.58	3	219	2	209	4.2e-52	171.3	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918745335	560	97.5	1	560	14	559	3.5e-129	426.8	COG2831	Hemolysin activation/secretion protein	554
2918745336	312	97.16	9	289	5	278	5.3e-49	161.2	COG1737	DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains	281
2918745337	389	95.22	11	388	16	413	4.4e-57	188.5	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
2918745338	332	97.49	11	331	8	318	8.2e-93	305.5	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918745339	333	91.08	7	323	3	298	2.1e-71	235.4	COG3491	Isopenicillin N synthase and related dioxygenases	322
2918745340	336	93.43	1	334	16	328	3.9e-35	116.2	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918745341	295	98.34	2	288	2	297	1.6e-57	190.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918745342	224	99.5	1	207	1	201	7.9e-42	137.5	COG1182	FMN-dependent NADH-azoreductase	202
2918745343	242	93.49	3	228	2	202	7.8e-10	30.2	COG0625	Glutathione S-transferase	211
2918745344	260	58.33	2	247	144	374	1.1e-29	97.9	COG0372	Citrate synthase	390
2918745345	503	95.95	3	502	15	559	3.5e-99	327.1	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2918745346	329	98.12	9	328	5	317	7.2e-97	318.9	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918745347	279	97.15	36	275	2	240	2.5e-45	148.8	COG1414	DNA-binding transcriptional regulator, IclR family	246
2918745348	316	98.53	25	307	3	270	5.8e-88	289	COG0313	16S rRNA C1402 (ribose-2'-O) methylase RsmI	275
2918745349	123	98.25	6	120	2	113	1.3e-29	97	COG0792	Predicted endonuclease distantly related to archaeal Holliday junction resolvase	114
2918745350	214	98.87	2	195	2	176	3.0e-41	132.5	COG0279	Phosphoheptose isomerase	176
2918745351	252	91.37	5	198	16	195	2.1e-40	133.5	COG2823	Osmotically-inducible protein OsmY, contains BON domain	196
2918745352	302	98.6	15	302	2	283	9.2e-108	354.4	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
2918745353	378	98.67	4	378	4	373	0.0e+00	619.1	COG5008	Tfp pilus assembly protein, ATPase PilU	375
2918745354	347	96.88	1	346	4	345	0.0e+00	535.5	COG2805	Tfp pilus assembly protein PilT, pilus retraction ATPase	353
2918745355	226	97.38	1	226	5	227	3.4e-81	266.9	COG0325	Uncharacterized pyridoxal phosphate-containing protein, affects Ilv metabolism, UPF0001 family	228
2918745356	157	96.84	1	155	5	157	6.5e-40	131.4	COG1522	DNA-binding transcriptional regulator, Lrp family	154
2918745357	993	13.32	421	530	6	108	0.0e+00	102.1	COG4230	Delta 1-pyrroline-5-carboxylate dehydrogenase	769
2918745357	993	57.7	521	990	143	588	0.0e+00	642.8	COG4230	Delta 1-pyrroline-5-carboxylate dehydrogenase	769
2918745357	993	95.04	10	422	20	402	2.9e-80	264.5	COG0506	Proline dehydrogenase	391
2918745359	423	98.79	13	422	6	412	0.0e+00	537.8	COG0334	Glutamate dehydrogenase/leucine dehydrogenase	411
2918745360	218	68.09	4	214	72	263	4.1e-43	141.9	COG1072	Panthothenate kinase	283
2918745362	342	44.46	4	336	357	661	1.5e-16	54.3	COG1289	Uncharacterized membrane protein YccC	674
2918745363	307	91.59	1	306	23	305	6.3e-74	243.4	COG0010	Arginase family enzyme	305
2918745364	685	99.7	7	681	2	675	0.0e+00	794.8	COG1505	Prolyl oligopeptidase PreP, S9A serine peptidase family	648
2918745368	211	77.03	2	208	14	174	4.0e-19	64.5	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918745369	257	47.8	22	249	18	158	3.8e-09	31	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918745370	1076	93.35	7	459	17	409	1.1e-79	262.6	COG2124	Cytochrome P450	411
2918745370	1076	94.81	445	1073	32	597	0.0e+00	469.7	COG0369	Sulfite reductase, alpha subunit (flavoprotein)	587
2918745371	418	94.81	18	399	6	352	5.9e-46	151.5	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918745372	232	79.9	29	229	11	177	4.1e-21	69.8	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918745373	537	96.48	3	537	10	557	2.5e-118	390.4	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2918745374	1098	7.28	664	735	119	165	0.0e+00	5	COG4770	Acetyl/propionyl-CoA carboxylase, alpha subunit	645
2918745374	1098	13.93	464	561	556	645	0.0e+00	51.6	COG4770	Acetyl/propionyl-CoA carboxylase, alpha subunit	645
2918745374	1098	71.98	1	491	2	466	0.0e+00	513.1	COG4770	Acetyl/propionyl-CoA carboxylase, alpha subunit	645
2918745375	445	90.5	206	440	10	209	1.3e-22	74.8	COG2755	Lysophospholipase L1 or related esterase	216
2918745377	285	98.26	1	285	5	286	4.4e-122	401.8	COG0788	Formyltetrahydrofolate hydrolase	287
2918745378	444	96.87	2	444	9	441	0.0e+00	468	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
2918745379	258	71.19	17	256	55	264	1.2e-26	88	COG3016	Uncharacterized iron-regulated protein	295
2918745380	353	96.31	4	353	11	349	3.1e-56	185.2	COG3180	Uncharacterized membrane protein AbrB, regulator of aidB expression	352
2918745383	357	98.9	4	335	2	271	6.6e-60	197.5	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
2918745384	259	73.75	186	259	16	74	9.9e-13	41.2	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2918745385	596	95.67	62	460	3	378	8.6e-65	213.7	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2918745387	324	98.12	3	323	5	317	1.1e-86	285.3	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918745388	403	33.91	49	156	96	174	6.0e-18	39.2	COG2849	Antitoxin component YwqK of the YwqJK toxin-antitoxin module	230
2918745388	403	35.62	200	399	142	224	6.0e-18	16.8	COG2849	Antitoxin component YwqK of the YwqJK toxin-antitoxin module	230
2918745389	137	98.55	1	137	3	138	1.7e-64	210.7	COG3565	Predicted dioxygenase of extradiol dioxygenase family	138
2918745390	380	90.64	32	318	28	298	7.4e-39	128.1	COG3735	Uncharacterized conserved protein YbaP, TraB family	299
2918745392	760	91.57	1	759	41	768	2.9e-53	176.3	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2918745393	302	78.57	143	302	22	142	5.5e-45	146.9	COG2847	Copper(I)-binding protein	151
2918745394	579	90.72	19	574	42	481	1.2e-81	269	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
2918745395	636	99.25	1	523	1	531	0.0e+00	567.6	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
2918745406	309	83.46	3	272	19	235	2.1e-39	130.1	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2918745407	563	97.54	13	563	4	557	7.3e-126	415.4	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2918745408	292	87.97	23	292	31	286	2.2e-105	346.5	COG3186	Phenylalanine-4-hydroxylase	291
2918745409	266	93.99	3	266	7	272	2.3e-36	120.1	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918745410	375	98.62	1	375	4	361	0.0e+00	494.7	COG3185	4-hydroxyphenylpyruvate dioxygenase and related hemolysins	363
2918745411	157	97.47	1	157	3	156	1.2e-41	137.1	COG1522	DNA-binding transcriptional regulator, Lrp family	154
2918745412	242	64.81	40	183	29	133	2.1e-07	25.5	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2918745413	292	91.81	3	291	11	279	1.0e-95	314.7	COG4535	Mg2+ and Co2+ transporter CorC, contains CBS pair and CorC-HlyC domains	293
2918745414	529	95.96	8	529	17	515	4.9e-108	356.5	COG0815	Apolipoprotein N-acyltransferase	518
2918745415	457	5.12	386	448	443	466	2.0e-39	10.7	COG0277	FAD/FMN-containing dehydrogenase	459
2918745415	457	42.22	15	331	30	227	2.0e-39	118.9	COG0277	FAD/FMN-containing dehydrogenase	459
2918745416	267	96.51	6	263	8	256	7.4e-63	206.7	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2918745417	276	97.21	18	272	4	247	1.0e-86	284.9	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2918745418	328	94.03	1	327	9	323	1.0e-37	124.6	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918745419	287	97.19	12	262	4	245	5.3e-71	233.4	COG1402	 Creatinine amidohydrolase/Fe(II)-dependent formamide hydrolase involved in riboflavin and F420 biosynthesis	250
2918745420	424	88.21	14	416	26	399	5.1e-30	98.6	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
2918745421	195	98.43	1	195	1	188	5.8e-42	138.3	COG2249	Putative NADPH-quinone reductase (modulator of drug activity B)	189
2918745422	407	95.7	13	407	10	387	9.0e-29	94.7	COG2814	Predicted arabinose efflux permease, MFS family	394
2918745423	313	98.01	9	306	3	297	2.4e-64	212.6	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918745425	239	92.79	49	239	2	194	2.2e-49	162.6	COG0288	Carbonic anhydrase	207
2918745426	236	92.34	17	224	7	199	1.9e-19	65.6	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918745427	356	94.13	7	356	18	354	5.2e-105	345.8	COG0252	L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D	351
2918745428	273	76.72	63	273	39	216	2.4e-24	81.6	COG0671	Membrane-associated phospholipid phosphatase	232
2918745429	274	66.84	4	249	3	266	5.6e-16	53	COG1409	3',5'-cyclic AMP phosphodiesterase CpdA	301
2918745430	321	96.69	9	316	6	297	5.0e-44	145	COG1597	Diacylglycerol kinase family enzyme	301
2918745431	301	97.65	1	291	5	295	0.0e+00	536.5	COG0752	Glycyl-tRNA synthetase, alpha subunit	298
2918745432	712	99.57	3	712	3	690	0.0e+00	731.3	COG0751	Glycyl-tRNA synthetase, beta subunit	691
2918745433	192	92.35	1	184	5	173	9.5e-49	159.9	COG0241	Histidinol phosphatase or a related phosphatase	181
2918745434	258	90.8	7	257	4	240	3.2e-45	149	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
2918745435	325	90.31	82	321	15	219	4.0e-51	168.1	COG1451	Predicted metal-dependent hydrolase	223
2918745436	256	98.88	7	253	2	266	1.4e-64	212.9	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918745437	303	81.85	27	297	51	289	3.9e-50	165.4	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
2918745439	359	85	17	335	18	238	2.5e-30	99.3	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2918745440	132	94.7	6	132	1	125	5.8e-26	86	COG0789	DNA-binding transcriptional regulator, MerR family	124
2918745441	259	95.19	2	203	3	200	9.0e-67	219.2	COG0288	Carbonic anhydrase	207
2918745442	606	98.27	6	604	3	570	0.0e+00	750.5	COG4579	Isocitrate dehydrogenase kinase/phosphatase	578
2918745443	394	99.24	2	394	2	392	1.2e-127	420.9	COG0183	Acetyl-CoA acetyltransferase	392
2918745444	416	98.33	31	415	7	417	1.1e-57	190.6	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
2918745445	376	96.74	1	376	7	392	0.0e+00	438.6	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918745446	142	84.11	2	142	4	130	1.1e-31	104.6	COG3012	Uncharacterized conserved protein YchJ, contains N- and C-terminal SEC-C domains	151
2918745448	628	99.54	131	592	2	433	0.0e+00	730.4	COG0422	Thiamine biosynthesis protein ThiC	432
2918745449	230	98.64	5	227	2	219	2.5e-53	175.8	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
2918745450	108	62.67	2	106	36	129	2.3e-08	29.1	COG0526	Thiol-disulfide isomerase or thioredoxin	127
2918745451	342	82.58	212	341	17	125	1.6e-21	69.8	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918745452	390	98.25	6	390	2	393	2.1e-125	413.5	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918745453	558	97.01	17	557	11	561	1.2e-129	427.7	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2918745454	540	99.43	12	540	3	525	0.0e+00	683.8	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component	526
2918745455	262	98.49	1	259	5	265	5.4e-62	204.2	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918745457	667	99.69	1	664	1	644	0.0e+00	884.9	COG4770	Acetyl/propionyl-CoA carboxylase, alpha subunit	645
2918745460	306	97.85	1	306	6	324	4.3e-69	227.5	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
2918745461	245	97.56	4	245	4	243	4.0e-47	154.8	COG1414	DNA-binding transcriptional regulator, IclR family	246
2918745462	127	74.81	6	123	22	119	5.7e-16	53.1	COG1917	Cupin domain protein related to quercetin dioxygenase	131
2918745463	336	97.81	16	335	7	318	2.6e-81	267.8	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918745464	408	98.5	1	397	6	400	3.7e-110	363.2	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2918745465	389	99.5	1	389	1	397	1.5e-104	344.9	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918745466	97	92.47	4	95	4	89	1.9e-25	83.9	COG1254	Acylphosphatase	92
2918745467	306	67.8	5	305	2	281	9.3e-67	220.3	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
2918745468	162	95.48	14	162	6	153	2.4e-34	112.8	COG2606	Cys-tRNA(Pro) deacylase, prolyl-tRNA editing enzyme YbaK/EbsC	155
2918745469	92	71.62	23	89	4	56	4.8e-19	62.7	COG3313	Predicted Fe-S protein YdhL, DUF1289 family	74
2918745470	214	95.57	1	191	8	201	1.4e-30	101	COG3917	2-hydroxychromene-2-carboxylate isomerase	203
2918745471	547	47.52	235	543	8	189	6.3e-34	8	COG0477	MFS family permease	338
2918745471	547	75.2	6	265	2	289	6.3e-34	104.6	COG0477	MFS family permease	338
2918745473	371	94.26	7	369	8	352	2.4e-44	146.3	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918745474	368	95.36	13	367	4	352	5.2e-45	148.6	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918745475	1949	31.77	1042	1372	5	303	0.0e+00	264.3	COG0178	Excinuclease UvrABC ATPase subunit	935
2918745475	1949	57.07	1356	1949	403	939	0.0e+00	758.3	COG0178	Excinuclease UvrABC ATPase subunit	935
2918745475	1949	99.47	1	1015	2	937	0.0e+00	1096.1	COG0178	Excinuclease UvrABC ATPase subunit	935
2918745476	349	99.09	1	323	3	329	1.8e-90	298.2	COG2423	Ornithine cyclodeaminase/archaeal alanine dehydrogenase, mu-crystallin family	330
2918745477	349	90.49	4	349	5	318	2.7e-86	284.2	COG0123	Acetoin utilization deacetylase AcuC or a related deacetylase	340
2918745478	327	97.49	5	322	8	318	4.2e-85	280.2	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918745479	189	80.86	7	185	13	181	2.2e-14	49.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918745480	420	45.43	227	414	13	186	3.7e-18	18.3	COG0477	MFS family permease	338
2918745480	420	66.84	20	252	6	261	3.7e-18	44.3	COG0477	MFS family permease	338
2918745481	278	97.06	30	275	7	270	9.8e-20	61.8	COG0561	Hydroxymethylpyrimidine pyrophosphatase and other HAD family phosphatases	264
2918745482	331	98.46	1	326	3	322	1.5e-105	347.6	COG4586	ABC-type uncharacterized transport system, ATPase component	325
2918745483	280	98.88	4	280	4	268	5.2e-25	82.9	COG4587	ABC-type uncharacterized transport system, permease component	268
2918745486	267	97.31	3	267	8	260	1.2e-54	180.3	COG3694	ABC-type uncharacterized transport system, permease component	260
2918745487	544	99.24	1	535	5	528	0.0e+00	746.8	COG4108	Peptide chain release factor RF-3	528
2918745489	163	67.72	1	159	48	154	6.4e-04	13.3	COG5490	Uncharacterized protein	158
2918745492	479	99.28	11	471	4	419	0.0e+00	645.8	COG0499	S-adenosylhomocysteine hydrolase	420
2918745493	263	97.96	1	259	3	242	6.3e-76	249.4	COG1189	Predicted rRNA methylase YqxC, contains S4 and FtsJ domains	245
2918745494	274	93.86	2	274	16	290	4.3e-83	273.3	COG0685	5,10-methylenetetrahydrofolate reductase	291
2918745495	200	47.18	55	199	85	201	1.2e-50	167.2	COG0797	Rare lipoprotein A, peptidoglycan hydrolase digesting "naked" glycans, contains C-terminal SPOR domain	233
2918745496	316	97.85	2	315	2	274	1.9e-90	295	COG2961	23S rRNA A2030 N6-methylase RlmJ	279
2918745497	143	95.27	2	143	2	142	4.6e-61	199.6	COG0102	Ribosomal protein L13	148
2918745498	112	84.21	1	112	22	133	2.0e-44	145.8	COG0103	Ribosomal protein S9	130
2918745499	121	96.36	12	121	4	109	2.3e-44	144.5	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
2918745500	375	99.2	1	375	2	372	1.7e-122	404.1	COG2377	1,6-Anhydro-N-acetylmuramate kinase	371
2918745501	446	45.25	42	421	160	302	3.1e-56	185.9	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
2918745502	410	98.27	13	410	7	403	1.7e-122	403.9	COG0162	Tyrosyl-tRNA synthetase	401
2918745503	205	56.78	3	205	84	196	8.5e-29	95.5	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
2918745504	163	33.04	15	163	65	176	4.5e-14	47.2	COG4254	Uncharacterized conserved protein, contains LysM and FecR  domains	339
2918745505	304	92.79	5	302	14	296	4.2e-79	260.3	COG0053	Divalent metal cation (Fe/Co/Zn/Cd) transporter	304
2918745506	146	99.31	1	145	1	144	4.3e-60	196.9	COG1490	D-Tyr-tRNAtyr deacylase	145
2918745507	152	86.36	10	152	19	151	1.6e-38	126.3	COG0319	ssRNA-specific RNase YbeY, 16S rRNA maturation enzyme	153
2918745508	313	92.65	3	312	16	330	2.2e-127	419.1	COG1702	Phosphate starvation-inducible protein PhoH, predicted ATPase	348
2918745509	190	99.5	1	189	1	200	2.5e-63	207.7	COG0632	Holliday junction resolvasome RuvABC DNA-binding subunit	201
2918745510	208	94	17	208	12	199	2.3e-50	165.7	COG4430	Uncharacterized conserved protein YdeI, YjbR/CyaY-like superfamily, DUF1801 family	200
2918745511	317	99.67	8	316	2	303	0.0e+00	440.6	COG4589	Predicted CDP-diglyceride synthetase/phosphatidate cytidylyltransferase	303
2918745512	240	62.07	37	239	61	222	7.6e-21	68.9	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
2918745514	449	81.47	4	215	21	209	4.4e+00	11.3	COG0671	Membrane-associated phospholipid phosphatase	232
2918745515	589	96.43	4	288	7	303	1.3e-71	235.3	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
2918745516	200	94.85	14	200	3	186	3.3e-27	90.5	COG0558	Phosphatidylglycerophosphate synthase	192
2918745517	354	97.59	13	344	7	330	0.0e+00	534.5	COG2255	Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit	332
2918745518	320	96.32	2	320	8	295	2.7e-81	267.5	COG1230	Co/Zn/Cd efflux system component	296
2918745519	289	99.59	36	273	1	240	5.4e-71	233.3	COG2908	UDP-2,3-diacylglucosamine pyrophosphatase LpxH	237
2918745520	429	16.46	100	160	118	144	4.7e-32	5.2	COG2010	Cytochrome c, mono- and diheme variants	150
2918745520	429	32.93	6	86	33	86	4.7e-32	20	COG2010	Cytochrome c, mono- and diheme variants	150
2918745520	429	67.07	301	427	41	150	4.7e-32	50.2	COG2010	Cytochrome c, mono- and diheme variants	150
2918745520	429	100	126	312	1	164	4.7e-32	40.7	COG2010	Cytochrome c, mono- and diheme variants	150
2918745521	243	72.59	120	235	25	122	2.5e-39	53.9	COG2863	Cytochrome c553	121
2918745521	243	95.56	6	140	5	133	2.5e-39	80.9	COG2863	Cytochrome c553	121
2918745523	484	99.12	1	473	3	454	0.0e+00	431.6	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
2918745524	220	95	3	214	10	199	3.3e-54	178.6	COG3145	Alkylated DNA repair dioxygenase AlkB	194
2918745527	222	96.24	20	220	3	181	1.6e-41	136.5	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918745529	259	99.25	1	256	3	265	3.1e-87	286.9	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918745531	618	87.24	19	555	1	499	0.0e+00	513.5	COG3975	Predicted metalloprotease, contains C-terminal PDZ domain	558
2918745532	240	96.79	1	239	6	246	5.1e-21	69.9	COG1651	Protein-disulfide isomerase	244
2918745533	378	31.04	4	127	4	125	2.0e-65	58.4	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2918745533	378	61.07	125	378	153	392	2.0e-65	163.8	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2918745534	293	95.56	9	289	2	259	3.0e-56	185.1	COG3217	Uncharacterized conserved protein YcbX, contains MOSC and Fe-S domains	270
2918745535	132	99.26	1	132	2	135	9.8e-44	143.1	COG1869	D-ribose pyranose/furanose isomerase RbsD	135
2918745536	322	98.1	16	313	1	310	1.2e-76	252.3	COG0524	Sugar or nucleoside kinase, ribokinase family	311
2918745537	369	99.4	2	336	1	332	1.4e-119	393.9	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
2918745538	327	96.87	12	325	8	316	3.0e-88	290.2	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
2918745539	547	98.6	11	515	7	500	0.0e+00	562.6	COG1129	ABC-type sugar transport system, ATPase component	500
2918745540	318	92.66	1	318	12	314	2.2e-77	254.7	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
2918745541	363	99.73	1	363	1	371	0.0e+00	486.7	COG0012	Ribosome-binding ATPase YchF, GTP1/OBG family	372
2918745542	224	97.67	1	220	2	211	1.5e-41	137.2	COG0625	Glutathione S-transferase	211
2918745543	156	92.55	1	155	7	155	1.2e-48	159.5	COG1238	Uncharacterized membrane protein YqaA, SNARE-associated domain	161
2918745544	352	98.46	3	327	2	321	9.1e-111	364.7	COG0042	tRNA-dihydrouridine synthase	323
2918745545	78	76.53	1	77	23	97	3.5e-29	95.9	COG2901	DNA-binding protein Fis (factor for inversion stimulation)	98
2918745546	535	99.81	1	535	2	515	0.0e+00	737.4	COG0138	AICAR transformylase/IMP cyclohydrolase PurH	515
2918745547	431	98.84	1	430	3	429	0.0e+00	595.1	COG0001	Glutamate-1-semialdehyde aminotransferase	432
2918745548	321	95.82	32	294	3	254	1.0e-31	104.4	COG0351	Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase	263
2918745549	56	94.55	3	56	2	53	1.1e-26	87.2	COG1773	Rubredoxin	55
2918745550	123	48.71	1	121	3	115	2.2e-30	100.3	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918745551	121	89.47	1	121	6	124	3.6e-34	112.2	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918745552	177	84.24	11	176	17	155	3.3e-14	47.3	COG0835	Chemotaxis signal transduction protein	165
2918745553	769	30.59	45	280	78	207	8.7e-85	4.3	COG0840	Methyl-accepting chemotaxis protein	408
2918745553	769	81.88	306	768	78	425	8.7e-85	280.3	COG0840	Methyl-accepting chemotaxis protein	408
2918745554	2018	15.25	1209	1352	9	123	0.0e+00	40.8	COG0643	Chemotaxis protein histidine kinase CheA	716
2918745554	2018	17.11	1052	1216	9	137	0.0e+00	15.8	COG0643	Chemotaxis protein histidine kinase CheA	716
2918745554	2018	46.02	659	1045	5	351	0.0e+00	60.7	COG0643	Chemotaxis protein histidine kinase CheA	716
2918745554	2018	55.31	1341	1862	333	749	0.0e+00	439.3	COG0643	Chemotaxis protein histidine kinase CheA	716
2918745554	2018	61.54	1885	2016	11	122	6.2e-10	33.3	COG4567	Two-component response regulator, ActR/RegA family, consists of REC and Fis-type HTH domains	182
2918745555	362	72.5	299	361	18	75	1.1e-13	43.6	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2918745558	515	99.14	13	493	4	462	0.0e+00	478.6	COG0415	Deoxyribodipyrimidine photolyase	461
2918745559	192	94.85	1	192	11	194	3.0e-66	217.1	COG1678	Putative transcriptional regulator, AlgH/UPF0301 family	194
2918745560	149	95.04	24	149	3	136	1.2e-31	103	COG0816	RNase H-fold protein, predicted Holliday junction resolvase in Firmicutes and mycoplasms, involved in anti-termination at Rho-dependent terminators	141
2918745561	165	70.39	13	162	31	156	3.5e-37	122.1	COG2065	Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase	179
2918745562	320	97.46	9	320	6	312	6.7e-111	364.8	COG0540	Aspartate carbamoyltransferase, catalytic chain	316
2918745563	428	97.22	2	428	3	421	3.0e-121	399.8	COG0044	Dihydroorotase or related cyclic amidohydrolase	430
2918745564	248	70.88	19	248	23	207	1.0e-27	91.5	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
2918745567	337	84.85	192	331	15	126	2.8e-26	86.1	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918745568	771	95.85	7	770	31	792	1.1e-77	256.9	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2918745569	375	67.15	149	369	49	232	8.9e-06	18.5	COG1240	Mg-chelatase subunit ChlD	261
2918745572	373	59.7	42	325	11	207	3.1e-38	125.8	COG0714	MoxR-like ATPase	329
2918745576	182	93.66	1	135	4	136	1.9e-08	26.6	COG1569	Predicted nucleic acid-binding protein, contains PIN domain	142
2918745577	162	43.88	1	146	183	329	7.2e-22	73	COG0582	Integrase	309
2918745581	340	97.81	9	337	7	318	4.3e-90	296.6	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918745583	509	97.02	1	503	1	489	0.0e+00	646.1	COG3333	TctA family transporter	504
2918745584	278	94.97	2	191	3	172	1.2e-10	34.1	COG1102	Cytidylate kinase	179
2918745585	202	90.37	15	201	2	198	3.2e-14	47.3	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2918745586	606	96.4	45	602	3	537	0.0e+00	450.7	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
2918745587	425	98.75	1	425	6	401	1.2e-122	404.3	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2918745588	145	49.17	1	127	121	239	6.8e-16	53.2	COG2202	PAS domain	232
2918745589	416	98.5	1	416	7	401	2.2e-123	406.7	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2918745591	389	99.48	1	387	1	381	0.0e+00	517.6	COG0045	Succinyl-CoA synthetase, beta subunit	387
2918745592	299	98.3	1	293	1	289	4.5e-122	401.4	COG0074	Succinyl-CoA synthetase, alpha subunit	293
2918745593	261	85.35	2	261	36	268	4.5e-57	188.3	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
2918745594	337	99.03	1	327	1	306	1.2e-75	248.7	COG1893	Ketopantoate reductase	307
2918745595	471	99.58	1	470	2	477	0.0e+00	548.1	COG0469	Pyruvate kinase	477
2918745596	315	97.01	4	298	2	293	1.5e-67	223	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918745598	441	53	232	439	6	208	1.4e-19	22.1	COG0477	MFS family permease	338
2918745598	441	63.19	27	267	9	250	1.4e-19	44.8	COG0477	MFS family permease	338
2918745600	282	96.68	1	281	1	291	1.5e-46	154	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918745601	89	12.85	10	82	241	290	2.7e-04	14.6	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
2918745602	1357	7.8	263	387	449	552	3.5e-84	16.3	COG2911	Autotransporter translocation and assembly factor TamB	1278
2918745602	1357	18.89	15	270	3	254	3.5e-84	29.8	COG2911	Autotransporter translocation and assembly factor TamB	1278
2918745602	1357	26.16	981	1356	982	1330	3.5e-84	205.4	COG2911	Autotransporter translocation and assembly factor TamB	1278
2918745602	1357	35.16	418	989	535	1003	3.5e-84	36.9	COG2911	Autotransporter translocation and assembly factor TamB	1278
2918745603	616	87.89	70	616	74	603	3.1e-76	251.8	COG0729	Outer membrane translocation and assembly module TamA	594
2918745604	395	99.75	1	395	1	392	0.0e+00	612.6	COG3825	Uncharacterized conserved protein,  contains von Willebrand factor type A (vWA) domain	393
2918745605	198	89.84	5	186	18	185	8.5e-27	89.1	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
2918745607	284	70.91	1	274	23	256	8.3e-58	190.6	COG0714	MoxR-like ATPase	329
2918745608	230	51.85	114	227	45	114	1.4e-40	46.8	COG2863	Cytochrome c553	121
2918745608	230	87.41	1	125	6	123	1.4e-40	86.6	COG2863	Cytochrome c553	121
2918745609	202	91.23	1	202	20	227	1.5e-39	130.5	COG3485	Protocatechuate 3,4-dioxygenase beta subunit	226
2918745610	241	95.61	10	241	11	228	2.6e-65	214.6	COG3485	Protocatechuate 3,4-dioxygenase beta subunit	226
2918745611	314	98.34	1	307	3	298	2.1e-57	189.8	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918745614	166	60.3	5	166	77	196	5.1e-40	132.4	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
2918745615	1023	86.56	617	1022	60	452	1.8e-60	199.1	COG0770	UDP-N-acetylmuramyl pentapeptide synthase	451
2918745617	614	74.82	27	588	164	695	8.9e-124	408.6	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
2918745618	434	96.92	11	425	11	388	8.4e-29	95.3	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918745619	517	96.96	18	458	3	448	4.5e-39	129	COG1538	Outer membrane protein TolC	457
2918745620	476	96.57	7	470	9	459	6.2e-97	319.8	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2918745621	679	8.32	422	522	377	423	7.5e-41	7	COG4655	Uncharacterized membrane protein	565
2918745621	679	65.66	5	390	4	374	7.5e-41	135.2	COG4655	Uncharacterized membrane protein	565
2918745622	164	46.43	4	145	10	100	2.7e-16	54.5	COG4961	Flp pilus assembly protein TadG	185
2918745623	161	42.86	4	140	16	99	3.1e-15	50.7	COG4961	Flp pilus assembly protein TadG	185
2918745625	311	70	14	249	30	211	3.3e-24	78.9	COG5010	Flp pilus assembly protein TadD, contains TPR repeats	257
2918745626	321	75.7	64	318	78	320	4.9e-32	105.5	COG2064	Pilus assembly protein TadC	320
2918745627	326	98.06	1	326	4	306	5.7e-53	174.3	COG4965	Flp pilus assembly protein TadB	309
2918745628	438	96.41	41	401	9	357	0.0e+00	458.4	COG4962	Pilus assembly protein, ATPase of CpaF family	355
2918745629	427	73.4	59	412	80	366	8.3e-52	170.5	COG4963	Flp pilus assembly protein, ATPase CpaE	366
2918745630	464	16.8	7	146	31	112	4.1e-94	15.6	COG4964	Flp pilus assembly protein, secretin CpaC	455
2918745630	464	55.74	137	441	169	440	4.1e-94	297.4	COG4964	Flp pilus assembly protein, secretin CpaC	455
2918745631	328	83.7	1	256	7	237	2.9e-42	138.9	COG3745	Flp pilus assembly protein CpaB	276
2918745632	165	85.12	2	161	13	155	5.8e-24	79	COG4960	Flp pilus assembly protein, protease CpaA	168
2918745633	61	98.28	1	61	1	57	2.3e-23	76.5	COG3847	Flp pilus assembly protein, pilin Flp	58
2918745634	475	63.33	194	430	44	233	7.2e-25	82	COG3034	Murein L,D-transpeptidase YafK	298
2918745635	394	44.84	11	382	99	263	4.6e-13	44.7	COG0457	Tetratricopeptide (TPR) repeat	291
2918745636	237	98.1	16	237	4	210	5.4e-46	151.4	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918745637	338	93.42	9	336	17	314	2.9e-64	211.7	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918745638	490	91.02	38	472	38	412	4.4e-56	184.8	COG4222	Uncharacterized conserved protein	391
2918745639	261	99.19	19	261	1	244	2.0e-72	237.6	COG1414	DNA-binding transcriptional regulator, IclR family	246
2918745640	233	98.18	2	223	2	217	3.4e-82	269.5	COG1788	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit	220
2918745641	214	93.33	1	214	2	211	6.4e-79	259.2	COG2057	Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit	225
2918745642	401	99.49	2	401	3	394	0.0e+00	446.4	COG0183	Acetyl-CoA acetyltransferase	392
2918745643	324	98.12	1	322	4	316	7.4e-80	263	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918745644	160	93.94	16	132	2	125	3.5e-26	86.5	COG0789	DNA-binding transcriptional regulator, MerR family	124
2918745646	246	98.28	7	241	2	229	8.8e-77	252	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918745647	139	95.8	1	139	5	141	1.7e-41	136.4	COG1764	Organic hydroperoxide reductase OsmC/OhrA	143
2918745648	459	83.76	11	455	56	385	6.2e-53	174.7	COG0642	Signal transduction histidine kinase	336
2918745649	596	69.33	251	453	16	119	2.9e-12	41.2	COG0526	Thiol-disulfide isomerase or thioredoxin	127
2918745649	596	93.39	1	219	13	224	4.8e-29	95.9	COG0785	Cytochrome c biogenesis protein CcdA	220
2918745651	315	95.45	1	314	6	320	4.1e-87	287	COG2423	Ornithine cyclodeaminase/archaeal alanine dehydrogenase, mu-crystallin family	330
2918745652	278	89.29	4	274	33	307	2.6e-31	103.6	COG1073	Fermentation-respiration switch protein FrsA, has esterase activity, DUF1100 family	299
2918745653	83	31.16	1	59	5	47	6.1e-06	21	COG3565	Predicted dioxygenase of extradiol dioxygenase family	138
2918745654	536	99.06	1	536	1	526	0.0e+00	833.1	COG4650	Sigma54-dependent transcription regulator containing an AAA-type ATPase domain and a DNA-binding domain	531
2918745655	383	9.97	2	51	25	54	1.6e-27	4.6	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
2918745655	383	17.94	297	357	244	297	1.6e-27	24	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
2918745655	383	56.81	148	311	24	194	1.6e-27	72.1	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
2918745656	407	98.92	10	407	6	463	5.3e-106	349.7	COG1690	RNA-splicing ligase RtcB, repairs tRNA damage	432
2918745658	281	95.18	32	278	2	238	2.7e-76	251	COG3541	Predicted nucleotidyltransferase	248
2918745659	345	97.36	1	343	2	333	1.1e-102	338.2	COG0430	RNA 3'-terminal phosphate cyclase	341
2918745660	547	84.84	316	545	21	227	4.2e-31	102.4	COG2114	Adenylate cyclase, class 3	227
2918745661	239	96.79	13	223	1	211	5.9e-32	105.4	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2918745662	159	90.28	22	158	10	139	3.1e-19	64.2	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
2918745663	252	98.46	6	252	3	257	3.8e-29	96.4	COG0730	Uncharacterized membrane protein YfcA	258
2918745664	119	98.29	2	119	2	116	5.0e-52	169.6	COG5507	Uncharacterized  conserved protein YbaA, DUF1428 family	117
2918745665	495	50.91	276	487	15	209	2.6e-40	11.5	COG0477	MFS family permease	338
2918745665	495	80.42	8	303	7	314	2.6e-40	125.1	COG0477	MFS family permease	338
2918745666	139	94.89	3	138	2	131	3.2e-40	131.9	COG2764	Uncharacterized conserved protein PhnB, glyoxalase superfamily	136
2918745667	145	95.62	2	145	2	132	1.6e-34	113.6	COG2764	Uncharacterized conserved protein PhnB, glyoxalase superfamily	136
2918745668	220	89.47	4	220	11	197	8.0e-19	63.8	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918745669	163	88.72	22	163	15	132	1.5e-24	81	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918745670	585	96.49	19	457	9	393	1.2e-96	319	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918745671	329	96.87	4	327	9	317	9.8e-69	226.4	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918745672	254	98.88	1	250	1	265	2.8e-52	172.5	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918745673	617	86.27	32	613	10	499	2.2e-59	195.8	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2918745674	257	98.11	1	254	3	262	1.9e-59	195.8	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918745675	288	80.26	1	288	58	301	5.7e-70	230.9	COG2159	Predicted metal-dependent hydrolase, TIM-barrel fold	293
2918745676	616	77.13	409	588	29	200	4.2e-33	109.8	COG1226	Voltage-gated potassium channel Kch	212
2918745676	616	96.25	1	400	2	386	6.5e-98	322.5	COG0475	Kef-type K+ transport system, membrane component KefB	397
2918745677	220	96.34	13	184	3	186	8.5e-43	140.8	COG2249	Putative NADPH-quinone reductase (modulator of drug activity B)	189
2918745678	206	20.45	1	69	2	55	6.1e-28	57.9	COG1192	Cellulose biosynthesis protein BcsQ	259
2918745678	206	43.94	75	204	127	242	6.1e-28	33.4	COG1192	Cellulose biosynthesis protein BcsQ	259
2918745679	153	88.05	1	153	18	157	5.9e-45	147.1	COG2030	Acyl dehydratase	159
2918745680	153	97.4	1	153	1	150	8.3e-62	202.3	COG0219	tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain	155
2918745681	238	95.54	12	235	10	223	1.7e-50	166.2	COG1040	Predicted amidophosphoribosyltransferases	225
2918745682	304	24.37	38	273	120	187	2.9e-05	18.6	COG0500	SAM-dependent methyltransferase	257
2918745683	158	87.2	14	158	19	161	2.4e-27	90.1	COG5488	Uncharacterized membrane protein	164
2918745684	392	83.86	14	301	24	236	7.2e-71	232.4	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
2918745685	543	90.86	19	542	5	521	0.0e+00	739.4	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
2918745687	208	90.15	3	205	13	195	2.0e-60	196.9	COG3175	Cytochrome c oxidase assembly protein Cox11	195
2918745689	293	94.84	53	293	9	210	4.0e-63	206.6	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
2918745691	269	96.06	6	267	8	251	5.5e-45	148	COG3346	Cytochrome oxidase assembly protein ShyY1	252
2918745693	406	9.38	15	53	93	124	1.6e-71	1.5	COG1612	Heme A synthase	323
2918745693	406	92.08	31	390	18	331	1.6e-71	235.5	COG1612	Heme A synthase	323
2918745694	301	93.81	2	301	15	302	5.3e-107	352.3	COG0109	Polyprenyltransferase (heme O synthase)	304
2918745695	205	89.05	6	205	22	208	4.0e-53	174.6	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
2918745696	279	77.25	142	279	17	145	1.4e-21	70.9	COG4335	3-methyladenine DNA glycosylase AlkC	167
2918745697	313	77.71	4	312	65	329	4.1e-84	277.4	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
2918745698	154	83.89	14	154	5	155	5.9e-21	68.1	COG4539	Uncharacterized membrane protein YGL010W	180
2918745699	237	94.79	25	237	3	202	9.8e-43	140.7	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918745700	597	76.9	50	440	89	391	9.9e-62	203.9	COG0642	Signal transduction histidine kinase	336
2918745702	414	87.78	77	414	44	359	8.3e-113	371.7	COG0552	Signal recognition particle GTPase	340
2918745703	483	95.88	32	467	11	429	2.7e-99	327.1	COG0612	Predicted Zn-dependent peptidase	438
2918745704	445	96.8	13	445	7	429	4.1e-79	260.7	COG0612	Predicted Zn-dependent peptidase	438
2918745705	305	98.01	2	303	2	296	5.9e-41	135.7	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918745706	211	98.02	6	207	3	200	2.6e-58	191.6	COG1279	Arginine exporter protein ArgO	202
2918745707	222	84.04	30	217	2	159	4.7e-40	131.6	COG0742	16S rRNA G966 N2-methylase RsmD	187
2918745708	167	98.11	3	162	3	158	1.8e-62	204.5	COG0669	Phosphopantetheine adenylyltransferase	159
2918745709	221	93.39	10	221	2	213	6.4e-82	268.8	COG2049	Allophanate hydrolase subunit 1	223
2918745710	332	97.47	2	326	3	310	5.3e-108	355.3	COG1984	Allophanate hydrolase subunit 2	314
2918745711	246	98.81	1	246	2	250	4.1e-109	358.4	COG1540	Lactam utilization protein B (function unknown)	252
2918745712	219	99.03	5	212	2	206	4.6e-85	279.3	COG2039	Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase)	207
2918745713	233	91.53	1	232	24	293	2.6e-32	107.2	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918745714	228	90.91	6	216	3	192	8.6e-52	170.5	COG0406	Broad specificity phosphatase PhoE	208
2918745715	531	16.58	26	136	4	99	7.0e-77	63	COG3653	N-acyl-D-aspartate/D-glutamate deacylase	579
2918745715	531	73.92	132	531	143	570	7.0e-77	194.7	COG3653	N-acyl-D-aspartate/D-glutamate deacylase	579
2918745717	132	89.86	67	131	4	65	1.5e-16	8.3	COG1942	Phenylpyruvate tautomerase PptA, 4-oxalocrotonate tautomerase family	69
2918745717	132	94.2	1	68	1	65	1.5e-16	44.9	COG1942	Phenylpyruvate tautomerase PptA, 4-oxalocrotonate tautomerase family	69
2918745718	289	97.67	4	289	2	295	8.5e-48	158.2	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918745719	208	65.41	12	208	18	208	5.8e-38	125.2	COG1284	Uncharacterized membrane-anchored protein YitT, contains DUF161 and DUF2179 domains	289
2918745720	467	99.58	3	465	2	480	3.2e-119	393.7	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
2918745721	495	94.29	1	493	17	561	9.8e-96	316.3	COG0747	ABC-type transport system, periplasmic component	556
2918745722	497	96.02	1	495	8	562	7.1e-89	293.7	COG0747	ABC-type transport system, periplasmic component	556
2918745723	276	81.88	7	270	2	263	1.2e-100	331.5	COG4608	ABC-type oligopeptide transport system, ATPase component	309
2918745724	329	99.38	3	319	1	323	3.3e-120	395.5	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
2918745725	291	94.63	3	290	15	296	3.0e-91	300	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2918745726	316	99.37	1	315	1	316	2.3e-111	366.8	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2918745727	99	59.68	1	88	40	113	1.0e-13	45.8	COG1145	Ferredoxin	99
2918745729	210	98.94	1	190	1	187	4.7e-70	229.6	COG0193	Peptidyl-tRNA hydrolase	190
2918745730	222	26.88	101	157	31	55	5.0e-31	2.7	COG1825	Ribosomal protein L25 (general stress protein Ctc)	93
2918745730	222	98.92	1	93	2	93	5.0e-31	96.8	COG1825	Ribosomal protein L25 (general stress protein Ctc)	93
2918745731	323	98.43	3	317	5	317	0.0e+00	442.1	COG0462	Phosphoribosylpyrophosphate synthetase	314
2918745733	262	85.17	1	257	35	281	3.9e-61	201.2	COG1947	4-diphosphocytidyl-2C-methyl-D-erythritol kinase	289
2918745734	173	47.09	12	147	47	143	6.8e-15	49.6	COG3017	Outer membrane lipoprotein LolB, involved in outer membrane biogenesis	206
2918745735	616	92.66	56	615	22	362	3.1e-19	49.4	COG0457	Tetratricopeptide (TPR) repeat	291
2918745736	270	100	1	270	1	274	7.9e-86	282.8	COG0266	Formamidopyrimidine-DNA glycosylase	273
2918745738	353	98.31	5	353	5	352	1.2e-116	384.6	COG1194	Adenine-specific DNA glycosylase, acts on AG and A-oxoG pairs	342
2918745739	292	98.95	3	292	2	284	1.5e-105	347.3	COG1660	RNase adaptor protein for sRNA GlmZ degradation, contains a P-loop ATPase domain	286
2918745740	559	99.28	2	556	2	555	0.0e+00	593.4	COG0497	DNA repair ATPase RecN	557
2918745741	303	94.39	17	300	17	285	3.2e-76	250.6	COG0061	NAD kinase	281
2918745750	80	24.12	3	73	96	150	1.4e-04	16.4	COG0705	Membrane associated serine protease, rhomboid family	228
2918745754	442	7.79	1	59	7	37	4.6e-19	25.6	COG4128	Zona occludens toxin, predicted ATPase	398
2918745754	442	22.11	134	412	124	211	4.6e-19	34.3	COG4128	Zona occludens toxin, predicted ATPase	398
2918745756	180	83.19	1	175	9	196	2.2e-42	139.9	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
2918745757	335	98.84	1	335	3	343	7.9e-104	342.4	COG1420	Transcriptional regulator of heat shock response	346
2918745761	193	99.34	33	184	1	151	2.9e-46	151.8	COG0782	Transcription elongation factor, GreA/GreB family	151
2918745762	752	98.07	23	748	14	723	0.0e+00	823.1	COG0317	(p)ppGpp synthase/hydrolase, HD superfamily	701
2918745763	67	91.89	1	67	1	68	5.7e-21	69	COG1758	DNA-directed RNA polymerase, subunit K/omega	74
2918745764	206	95.38	1	197	6	191	7.3e-75	245.5	COG0194	Guanylate kinase	191
2918745765	304	99.66	2	304	2	290	8.3e-81	266.3	COG1561	Uncharacterized conserved protein YicC, UPF0701 family	290
2918745766	335	66.81	12	331	2	315	1.3e-43	144.3	COG0515	Serine/threonine protein kinase	384
2918745767	304	93.01	1	257	8	260	2.5e-45	149.3	COG0631	Serine/threonine protein phosphatase PrpC	262
2918745768	243	96.1	2	241	9	230	7.7e-94	307.8	COG0689	Ribonuclease PH	230
2918745769	201	98.46	2	199	2	193	1.5e-56	185.6	COG0127	Inosine/xanthosine triphosphate pyrophosphatase, all-alpha NTP-PPase family	194
2918745770	419	91.43	15	419	31	414	8.1e-121	398.1	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
2918745772	439	90.89	4	437	24	432	2.1e-29	96.5	COG2271	Sugar phosphate permease	448
2918745773	400	92.57	5	388	5	378	6.5e-44	145.2	COG1680	CubicO group peptidase, beta-lactamase class C family	390
2918745774	242	97.48	1	240	4	235	4.5e-42	138.8	COG3473	Maleate cis-trans isomerase	238
2918745775	475	98.14	6	454	2	424	2.4e-109	360.5	COG0044	Dihydroorotase or related cyclic amidohydrolase	430
2918745776	251	96.52	1	228	1	222	2.9e-46	152.3	COG4126	Asp/Glu/hydantoin racemase	230
2918745777	235	92.67	4	231	12	226	2.6e-55	182	COG1802	DNA-binding transcriptional regulator, GntR family	230
2918745778	296	95.68	3	296	8	295	4.6e-46	152.6	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918745779	324	96.55	1	322	10	317	2.4e-77	254.9	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918745780	393	95.26	1	392	5	386	0.0e+00	449.1	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2918745781	252	92.08	2	252	14	257	8.0e-53	174	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918745782	313	48.12	50	242	47	161	5.8e-15	49.5	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
2918745783	412	70.45	8	361	22	269	2.9e-07	14.3	COG1566	Multidrug resistance efflux pump	352
2918745785	1135	84.95	57	500	14	442	1.2e-48	160.4	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
2918745785	1135	97.83	677	1135	2	451	2.7e-97	320.9	COG1538	Outer membrane protein TolC	457
2918745786	93	96.81	1	93	2	92	2.4e-34	112.2	COG0776	Bacterial nucleoid DNA-binding protein	94
2918745788	135	20.99	6	127	3	100	3.2e-05	17.6	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2918745791	668	96.45	4	649	13	665	0.0e+00	488	COG2982	Uncharacterized protein involved in outer membrane biogenesis	648
2918745792	148	96.23	1	148	4	156	4.1e-29	97.1	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2918745793	407	68.93	101	406	71	283	1.1e-18	60.8	COG3386	Sugar lactone lactonase YvrE	307
2918745794	264	98.88	3	261	2	266	2.1e-52	172.9	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918745795	234	92.86	22	233	9	190	1.8e-42	139.8	COG0693	Putative intracellular protease/amidase	188
2918745796	305	97.67	1	297	3	296	5.1e-69	227.9	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918745797	216	95.45	9	213	8	196	8.8e-76	248.3	COG0378	Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase	202
2918745798	223	99.56	1	223	2	229	4.5e-59	195	COG0830	Urease accessory protein UreF	229
2918745799	204	86.54	1	170	20	154	2.2e-39	129.3	COG2371	Urease accessory protein UreE	155
2918745800	572	100	1	572	1	569	0.0e+00	1026.2	COG0804	Urease alpha subunit	568
2918745802	101	95.28	1	101	1	101	2.3e-46	150.9	COG0832	Urease beta subunit	106
2918745803	199	95.52	1	199	10	201	8.4e-53	173.4	COG2370	Hydrogenase/urease accessory protein HupE	201
2918745804	100	99	1	100	1	99	9.7e-54	174.4	COG0831	Urease gamma subunit	100
2918745805	1209	85.28	589	984	56	391	1.5e-70	233.5	COG0642	Signal transduction histidine kinase	336
2918745805	1209	93.23	1000	1143	5	128	2.5e-21	68.9	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918745805	1209	93.53	34	502	14	432	4.0e-18	59.1	COG1457	Purine-cytosine permease or related protein	442
2918745806	343	53.02	18	183	3	125	2.4e-42	138.9	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918745806	343	82.5	257	334	10	75	1.4e-18	59.9	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2918745808	102	56.17	2	101	11	101	2.5e-03	12.4	COG4701	Uncharacterized protein	162
2918745809	930	99.76	2	923	3	840	0.0e+00	1271	COG0653	Preprotein translocase subunit SecA (ATPase, RNA helicase)	822
2918745810	409	97.28	4	409	12	405	0.0e+00	498.5	COG1364	N-acetylglutamate synthase (N-acetylornithine aminotransferase)	404
2918745811	291	96.54	1	291	5	283	3.6e-110	362.2	COG2607	Predicted ATPase, AAA+ superfamily	287
2918745812	155	87.79	9	149	12	162	8.5e-21	69	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2918745813	651	95.89	1	367	10	382	8.7e-97	318.8	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
2918745814	70	76.92	8	68	7	56	2.0e-21	70.1	COG3024	Endogenous inhibitor of DNA gyrase, YacG/DUF329 family	65
2918745815	251	99.18	1	251	2	243	4.8e-74	243.6	COG4582	Cell division protein ZapD, interacts with FtsZ	244
2918745817	503	92.29	8	446	6	400	1.9e-106	350.8	COG1696	D-alanyl-lipoteichoic acid acyltransferase DltB, MBOAT superfamily	425
2918745818	201	96.02	1	199	2	194	1.7e-52	172.7	COG0237	Dephospho-CoA kinase	201
2918745819	321	96.09	9	310	5	250	4.3e-65	214.4	COG1989	Prepilin signal peptidase PulO (type II secretory pathway) or related peptidase	254
2918745820	409	99.25	15	409	3	397	0.0e+00	472.2	COG1459	Type II secretory pathway, component PulF	397
2918745821	555	98.82	49	555	6	507	0.0e+00	593.6	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
2918745823	330	98.48	13	330	5	327	8.5e-103	338.3	COG0142	Geranylgeranyl pyrophosphate synthase	322
2918745824	103	99.03	1	103	1	102	1.0e-41	136.3	COG0261	Ribosomal protein L21	103
2918745825	85	95.4	1	85	1	83	6.8e-41	132.8	COG0211	Ribosomal protein L27	87
2918745826	362	93.11	1	353	1	338	0.0e+00	466	COG0536	GTPase involved in cell partioning and DNA repair	369
2918745827	379	99.19	8	377	3	369	0.0e+00	443.3	COG0263	Glutamate 5-kinase	369
2918745829	225	92.44	1	164	11	169	3.4e-25	83.3	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2918745830	581	99.24	1	576	1	523	0.0e+00	659.6	COG0442	Prolyl-tRNA synthetase	500
2918745831	224	59.08	8	217	85	263	6.5e-30	99.4	COG0741	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)	296
2918745832	427	97.95	1	427	2	430	9.1e-122	401.5	COG1253	Hemolysin or related protein, contains CBS domains	429
2918745833	166	97.18	9	162	5	142	3.4e-52	170.4	COG4101	Uncharacterized protein, RmlC-like cupin domain	142
2918745834	110	95.24	1	107	2	101	6.8e-45	145.9	COG0278	Glutaredoxin-related protein	105
2918745835	283	95.82	5	282	9	283	1.1e-75	248.9	COG2890	Methylase of polypeptide chain release factors	280
2918745836	362	98.9	1	359	4	362	0.0e+00	522.5	COG0216	Protein chain release factor A	363
2918745837	423	99.28	1	423	1	411	0.0e+00	460.3	COG0373	Glutamyl-tRNA reductase	414
2918745839	255	84.86	5	206	24	208	3.1e-20	67	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2918745840	148	89.73	1	147	13	143	6.6e-14	46.9	COG3418	Flagellar biosynthesis/type III secretory pathway chaperone	146
2918745841	98	90.32	1	91	7	90	1.4e-11	39.7	COG2747	Negative regulator of flagellin synthesis (anti-sigma28 factor)	93
2918745842	237	87.27	13	236	26	217	1.2e-36	121.1	COG1261	Flagella basal body P-ring formation protein FlgA	220
2918745843	136	97.78	2	136	2	133	6.7e-43	140.9	COG1815	Flagellar basal body rod protein FlgB	133
2918745844	138	98.55	5	138	3	138	9.5e-56	182.4	COG1558	Flagellar basal body rod protein FlgC	137
2918745845	228	98.21	1	228	2	220	7.2e-55	180.7	COG1843	Flagellar hook assembly protein FlgD	222
2918745846	404	99.15	1	404	4	471	1.2e-104	343.1	COG1749	Flagellar hook protein FlgE	423
2918745847	248	99.2	1	248	1	249	4.3e-96	316	COG4787	Flagellar basal body rod protein FlgF	251
2918745848	260	98.87	1	260	1	262	1.0e-103	341.1	COG4786	Flagellar basal body rod protein FlgG	265
2918745849	187	80.09	1	184	46	230	2.1e-64	211.9	COG2063	Flagellar basal body L-ring protein FlgH	230
2918745850	371	98.63	7	371	6	365	0.0e+00	488.5	COG1706	Flagellar basal body P-ring protein FlgI	365
2918745851	323	56.07	32	323	103	259	8.2e-65	213.5	COG1705	Flagellum-specific peptidoglycan hydrolase FlgJ	201
2918745852	168	88.48	9	166	13	158	1.0e-47	156.2	COG0835	Chemotaxis signal transduction protein	165
2918745853	287	76.19	182	259	10	73	2.1e-09	32.5	COG2770	HAMP domain	83
2918745855	230	91.38	2	226	15	226	7.5e-57	187	COG1802	DNA-binding transcriptional regulator, GntR family	230
2918745856	575	97.92	2	563	11	576	0.0e+00	588.6	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
2918745857	236	95.28	1	223	8	209	6.8e-58	190.3	COG0684	Regulator of RNase E activity RraA	210
2918745858	331	96.55	7	330	9	316	4.9e-94	309.6	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918745859	302	97.34	4	297	2	294	2.3e-50	166.6	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918745860	217	96.12	14	210	2	199	1.7e-18	56.8	COG1335	Nicotinamidase-related amidase	205
2918745861	95	98.92	1	95	1	92	2.9e-35	115	COG4317	Xanthosine utilization system component, XapX domain	93
2918745862	633	99.25	4	541	4	534	0.0e+00	584.7	COG1574	Predicted amidohydrolase YtcJ	535
2918745863	134	84.03	1	130	8	128	2.3e-23	77.8	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
2918745864	533	48.04	21	234	4	187	2.0e-19	56.4	COG0477	MFS family permease	338
2918745864	533	48.83	225	463	10	196	2.0e-19	14.8	COG0477	MFS family permease	338
2918745865	273	98.31	1	273	4	293	4.5e-49	162.2	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918745866	366	99.71	1	353	1	349	2.5e-127	419.6	COG3839	ABC-type sugar transport system, ATPase component	338
2918745867	254	92.95	13	248	9	232	2.0e-59	195.3	COG2186	DNA-binding transcriptional regulator, FadR family	241
2918745868	455	97.29	11	451	10	440	5.6e-42	139.1	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
2918745869	300	95.64	6	300	8	292	2.9e-71	234.8	COG1175	ABC-type sugar transport system, permease component	295
2918745870	278	93.99	3	277	18	283	4.6e-76	250.5	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
2918745871	267	92.96	5	267	4	267	3.7e-61	201.3	COG0169	Shikimate 5-dehydrogenase	283
2918745872	327	98.43	2	325	2	315	4.0e-84	276.9	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918745873	272	98.82	1	256	4	255	2.0e-98	323.3	COG3836	2-keto-3-deoxy-L-rhamnonate aldolase RhmA	255
2918745874	587	98.1	3	576	7	573	0.0e+00	578.5	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
2918745875	259	96.53	10	256	8	257	2.9e-16	54.1	COG0730	Uncharacterized membrane protein YfcA	258
2918745876	349	95.1	6	330	7	297	4.1e-62	204.7	COG3684	Tagatose-1,6-bisphosphate aldolase	306
2918745877	305	98.1	7	302	1	310	1.5e-55	183	COG0524	Sugar or nucleoside kinase, ribokinase family	311
2918745878	354	99.71	1	347	1	349	0.0e+00	471.5	COG3839	ABC-type sugar transport system, ATPase component	338
2918745879	324	98.58	1	323	2	349	9.8e-57	186.7	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
2918745880	270	95.41	2	269	14	283	1.5e-74	245.5	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
2918745881	289	93.96	1	289	13	292	1.1e-82	272.5	COG1175	ABC-type sugar transport system, permease component	295
2918745882	243	98.51	7	241	4	267	1.1e-62	206.6	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918745883	442	97.74	10	441	8	440	5.0e-65	215.2	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
2918745884	347	99.1	6	339	3	333	2.7e-101	333.8	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
2918745885	155	85.71	19	144	18	131	1.7e-17	58.2	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918745886	321	99.25	1	260	2	267	1.4e-61	202.7	COG1018	Ferredoxin-NADP reductase	266
2918745887	351	92.55	1	347	23	370	1.5e-84	278.9	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
2918745888	445	51.7	252	444	2	199	5.3e-32	22.6	COG0477	MFS family permease	338
2918745888	445	75.72	15	297	8	297	5.3e-32	89.1	COG0477	MFS family permease	338
2918745889	501	96.72	304	494	5	181	1.7e-48	158.2	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2918745890	653	97.71	13	651	11	608	0.0e+00	539.1	COG3284	Transcriptional regulator of acetoin/glycerol metabolism	606
2918745891	506	99.37	19	501	2	477	0.0e+00	581	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918745894	474	88.48	14	461	41	447	2.7e-34	111.8	COG1538	Outer membrane protein TolC	457
2918745895	471	29.34	197	336	335	476	3.4e-67	103.3	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
2918745895	471	36.78	4	213	1	178	3.4e-67	132.9	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
2918745896	168	96.2	7	163	6	157	5.6e-47	154.5	COG4454	Uncharacterized copper-binding protein, cupredoxin-like subfamily	158
2918745897	95	64.81	2	93	38	107	3.9e-26	86	COG5569	Periplasmic Cu and Ag efflux protein CusF	108
2918745900	1609	5.84	549	650	79	128	1.1e-77	.8	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
2918745900	1609	12.97	714	837	17	127	1.1e-77	56.3	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
2918745900	1609	14.49	628	771	25	148	1.1e-77	36.5	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
2918745900	1609	37.38	1118	1578	421	740	1.1e-77	131.3	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
2918745900	1609	37.5	844	1173	22	342	1.1e-77	78.6	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
2918745901	971	94.81	2	597	15	562	0.0e+00	560.7	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
2918745902	388	92.23	9	387	25	368	6.7e-52	170.9	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
2918745903	234	97.39	4	231	6	266	1.2e-45	150.5	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918745904	323	96.24	3	321	8	314	4.9e-81	266.8	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918745905	312	97.66	3	312	4	295	4.2e-63	207.6	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
2918745906	308	97.34	8	308	1	293	8.0e-45	148.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918745907	294	97.01	1	293	1	292	2.4e-61	202.7	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918745908	183	75.35	25	173	5	111	1.3e-07	22.3	COG1661	Predicted DNA-binding protein with PD1-like DNA-binding motif	141
2918745909	133	81.69	6	128	5	120	1.3e-09	32.2	COG1661	Predicted DNA-binding protein with PD1-like DNA-binding motif	141
2918745910	271	98.88	6	253	3	267	4.4e-73	240.7	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918745911	390	97.46	2	389	3	386	2.8e-70	232	COG0183	Acetyl-CoA acetyltransferase	392
2918745912	529	97.01	2	527	10	560	3.4e-116	383.3	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2918745913	337	96.99	2	334	6	327	1.9e-100	330.8	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
2918745914	622	84.75	19	187	14	163	1.3e-37	123.7	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
2918745914	622	98.42	248	622	1	373	3.9e-95	313.7	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
2918745916	277	96.6	17	277	6	261	1.0e-73	242.4	COG0300	Short-chain dehydrogenase	265
2918745917	221	76.56	7	221	4	163	9.0e-12	40.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918745919	598	90.8	79	594	35	508	0.0e+00	432.7	COG3540	Phosphodiesterase/alkaline phosphatase D	522
2918745920	286	89.86	1	263	2	249	2.0e-39	130.2	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
2918745921	271	68.75	26	126	28	115	9.1e-08	26	COG1708	Predicted nucleotidyltransferase	128
2918745922	328	97.18	7	326	7	316	1.4e-71	235.7	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918745923	324	97.81	3	323	6	317	5.7e-79	260.1	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918745924	268	52.02	11	245	165	370	1.1e-29	97.9	COG0372	Citrate synthase	390
2918745925	305	64.47	50	280	44	190	7.0e-37	119.3	COG3485	Protocatechuate 3,4-dioxygenase beta subunit	226
2918745926	387	93.77	1	380	8	383	2.4e-112	370.3	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2918745927	303	97.67	1	295	1	294	3.5e-70	231.7	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918745929	205	45.35	24	187	49	170	1.3e-17	58.3	COG5340	Transcriptional regulator, predicted component of viral defense system	269
2918745933	414	97.05	21	390	6	268	5.2e-70	230.6	COG0584	Glycerophosphoryl diester phosphodiesterase	257
2918745934	481	94.74	18	478	3	434	1.4e-121	401	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
2918745935	247	75.08	1	225	2	242	6.8e-24	73.8	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2918745936	179	80.15	47	173	14	118	1.3e-18	61.5	COG1917	Cupin domain protein related to quercetin dioxygenase	131
2918745937	146	72.09	5	137	22	145	2.0e-18	61.3	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2918745938	231	92.92	1	231	13	235	3.6e-63	207.8	COG0284	Orotidine-5'-phosphate decarboxylase	240
2918745939	334	76.52	8	136	3	103	1.6e-21	71	COG0789	DNA-binding transcriptional regulator, MerR family	124
2918745940	492	98.75	13	491	2	474	0.0e+00	594.8	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918745941	362	98.85	2	362	3	346	1.9e-124	409.8	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
2918745942	541	98.73	2	528	6	550	0.0e+00	555.6	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
2918745943	301	88.26	14	300	26	288	1.0e-67	222.7	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2918745944	318	99.06	1	318	2	316	3.6e-97	320.3	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2918745945	540	97.58	24	537	7	570	1.4e-79	262.9	COG0747	ABC-type transport system, periplasmic component	556
2918745946	430	95.1	21	410	3	371	4.2e-73	241.4	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918745947	221	96.1	3	220	3	224	1.4e-29	98.2	COG1011	FMN phosphatase YigB, HAD superfamily	229
2918745948	292	72.9	28	143	32	144	1.3e-09	32.2	COG2153	Predicted N-acyltransferase, GNAT family	155
2918745949	310	91.1	2	310	30	326	3.5e-77	254	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
2918745950	467	98.43	9	460	5	444	0.0e+00	476.9	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
2918745951	164	91.14	3	156	5	148	1.6e-38	126.7	COG1522	DNA-binding transcriptional regulator, Lrp family	154
2918745952	86	52.81	1	83	2	48	4.9e-13	44.1	COG3609	Transcriptional regulator, contains Arc/MetJ-type RHH (ribbon-helix-helix) DNA-binding domain	89
2918745953	105	94.95	2	105	4	97	2.2e-14	48.5	COG3668	Plasmid stabilization system protein ParE	98
2918745954	486	47.78	269	484	25	207	1.9e-39	15.3	COG0477	MFS family permease	338
2918745954	486	81.2	10	309	4	314	1.9e-39	118.6	COG0477	MFS family permease	338
2918745955	323	99.06	1	321	2	317	5.5e-74	243.8	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918745956	469	97.09	1	465	8	474	7.6e-121	399	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
2918745957	299	98.67	4	299	1	297	4.3e-56	185.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918745958	166	11.33	2	72	164	209	2.0e-03	10.4	COG0786	Na+/glutamate symporter	404
2918745958	166	14.78	79	164	179	238	2.0e-03	3	COG0786	Na+/glutamate symporter	404
2918745959	93	45.38	6	92	2	60	1.7e-13	46.2	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918745961	232	98.7	3	230	2	229	1.0e-33	111.7	COG1011	FMN phosphatase YigB, HAD superfamily	229
2918745963	329	96.24	9	326	7	313	9.6e-79	259.3	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918745964	315	97.34	1	296	1	293	4.2e-49	162.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918745965	135	92.65	3	130	10	135	4.9e-28	92.3	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
2918745966	296	97.34	3	296	4	296	2.8e-55	182.8	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918745967	186	78.41	1	156	39	176	1.8e-12	41.4	COG4719	Uncharacterized protein	176
2918745971	273	98.71	39	266	2	230	1.2e-27	91.3	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918745972	1059	76.29	565	1059	157	658	4.2e-51	169.2	COG3468	Type V secretory pathway, adhesin AidA	644
2918745973	191	62.81	3	187	73	197	2.4e-26	87.9	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
2918745974	243	95.41	5	234	9	216	4.2e-15	50.4	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2918745977	190	86.56	2	174	17	177	1.1e-32	107.8	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918745978	333	97.52	1	333	7	321	1.7e-76	251.8	COG3712	Periplasmic ferric-dicitrate binding protein FerR, regulates iron transport through sigma-19	322
2918745979	838	94.34	88	838	22	771	7.1e-59	194.8	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2918745980	461	50.39	254	458	1	193	1.5e-22	8.2	COG0477	MFS family permease	338
2918745980	461	52.22	27	250	5	204	1.5e-22	72.8	COG0477	MFS family permease	338
2918745981	557	84.9	2	410	34	376	4.3e-61	201.8	COG1680	CubicO group peptidase, beta-lactamase class C family	390
2918745982	788	92.88	493	781	5	278	3.4e-23	77.7	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918745982	788	98.59	1	487	1	488	0.0e+00	513.1	COG5476	Microcystin degradation protein MlrC, contains DUF1485 domain	488
2918745983	383	95.69	2	381	14	368	7.0e-86	282.8	COG3616	D-serine deaminase, pyridoxal phosphate-dependent	368
2918745984	284	96.76	75	283	2	210	6.8e-52	171.1	COG0811	Biopolymer transport protein ExbB/TolQ	216
2918745985	142	94.24	3	141	7	137	4.7e-33	108.7	COG0848	Biopolymer transport protein ExbD	137
2918745986	145	91.37	3	142	10	136	4.5e-29	95.7	COG0848	Biopolymer transport protein ExbD	137
2918745989	252	95.42	1	250	10	238	7.6e-52	169.3	COG5343	Anti-sigma-K factor RskA	240
2918745990	191	91.4	9	190	10	179	1.1e-36	120.9	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918745992	185	71.71	5	185	54	200	2.1e-51	169.5	COG2335	Uncaracterized surface protein containing fasciclin (FAS1) repeats	187
2918745995	153	94.3	1	151	5	153	2.7e-29	96.9	COG1522	DNA-binding transcriptional regulator, Lrp family	154
2918745996	106	71.85	1	105	14	110	2.3e-17	57.9	COG3791	Uncharacterized conserved protein	133
2918745997	269	99.17	5	253	2	241	9.8e-105	343.6	COG1126	ABC-type polar amino acid transport system, ATPase component	240
2918745998	264	93.42	17	264	13	225	2.8e-68	224.5	COG0765	ABC-type amino acid transport system, permease component	222
2918745999	277	93.29	3	272	6	269	1.5e-32	107.5	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918746000	418	97.42	1	418	5	382	4.9e-61	200	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918746001	583	97.84	1	570	2	544	0.0e+00	451.7	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
2918746002	376	95.1	6	369	2	370	1.0e-65	216.8	COG1748	Saccharopine dehydrogenase, NADP-dependent	389
2918746003	308	89.32	29	303	23	298	6.4e-51	167.7	COG3386	Sugar lactone lactonase YvrE	307
2918746004	295	98.57	19	293	4	279	2.1e-54	179.6	COG3618	Predicted metal-dependent hydrolase, TIM-barrel fold	279
2918746005	318	96.24	1	316	8	314	8.4e-87	285.8	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918746006	308	92.94	2	308	9	311	6.5e-87	285.9	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
2918746007	229	87.26	9	218	20	204	7.6e-56	183.5	COG0684	Regulator of RNase E activity RraA	210
2918746008	328	98.43	4	327	5	318	6.0e-86	283	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918746009	302	98.21	20	294	5	279	1.2e-51	170.5	COG3618	Predicted metal-dependent hydrolase, TIM-barrel fold	279
2918746010	336	97.49	12	334	6	316	4.4e-102	335.9	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918746011	299	98.67	1	299	1	297	7.2e-56	184.8	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918746012	164	45.42	8	164	61	174	4.6e-16	49.6	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2918746013	215	84.49	6	171	4	161	1.4e-30	101	COG4185	Predicted ABC-type ATPase	187
2918746014	115	62.79	11	79	7	60	8.1e-04	13.6	COG2161	Antitoxin component YafN of the YafNO toxin-antitoxin module, PHD/YefM family	86
2918746015	274	52.83	142	274	73	156	5.3e-18	49.6	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2918746015	274	76.1	1	142	6	126	5.3e-18	11.6	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2918746016	450	99.77	1	450	1	436	3.9e-92	303.5	COG1236	RNA processing exonuclease, beta-lactamase fold, Cft2 family	427
2918746017	700	45.05	570	698	11	92	2.2e-05	18	COG4567	Two-component response regulator, ActR/RegA family, consists of REC and Fis-type HTH domains	182
2918746017	700	66.75	242	561	125	387	2.5e-51	169.9	COG0642	Signal transduction histidine kinase	336
2918746018	249	98.71	5	246	2	230	7.9e-75	245.7	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918746019	343	99.41	1	341	1	339	1.9e-130	429.4	COG1064	D-arabinose 1-dehydrogenase, Zn-dependent alcohol dehydrogenase family	339
2918746020	217	30.46	1	71	129	188	1.3e-31	34.5	COG2823	Osmotically-inducible protein OsmY, contains BON domain	196
2918746020	217	77.66	62	217	44	196	1.3e-31	73.3	COG2823	Osmotically-inducible protein OsmY, contains BON domain	196
2918746021	150	96.86	1	148	4	157	1.4e-29	98.5	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2918746022	124	89.17	4	124	9	115	6.8e-24	79.4	COG1734	RNA polymerase-binding transcription factor DksA	120
2918746023	499	25.21	389	486	267	358	6.1e-104	30.8	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
2918746023	499	93.42	8	379	18	358	6.1e-104	314	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
2918746025	140	94.97	1	140	6	156	1.8e-20	68.9	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2918746026	217	34.01	1	70	129	195	8.2e-39	41.3	COG2823	Osmotically-inducible protein OsmY, contains BON domain	196
2918746026	217	78.17	64	217	42	195	8.2e-39	90.1	COG2823	Osmotically-inducible protein OsmY, contains BON domain	196
2918746027	169	41.8	4	161	12	141	2.8e-15	50.9	COG0078	Ornithine carbamoyltransferase	310
2918746028	264	88.07	18	238	18	209	2.4e-33	109.9	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2918746029	147	65.4	1	145	19	156	2.7e-24	80.8	COG2391	Uncharacterized membrane protein YedE/YeeE, contains two sulfur transport domains	198
2918746030	144	70.62	2	144	16	164	4.9e-26	86.4	COG2391	Uncharacterized membrane protein YedE/YeeE, contains two sulfur transport domains	198
2918746031	108	77.97	15	108	18	109	2.6e-19	64.4	COG0640	DNA-binding transcriptional regulator, ArsR family	110
2918746032	297	89.62	1	270	17	249	1.3e-43	144	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2918746033	245	52.09	18	193	18	179	8.8e-15	48.1	COG0078	Ornithine carbamoyltransferase	310
2918746037	280	72.33	152	280	42	156	1.8e-25	62.3	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2918746037	280	96.23	1	150	4	156	1.8e-25	27.7	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2918746038	509	82.79	3	322	20	298	4.6e-86	283.1	COG2187	Aminoglycoside phosphotransferase family enzyme	337
2918746038	509	96.47	328	505	2	165	3.5e-39	129.2	COG0645	Predicted kinase	170
2918746039	398	96.72	11	397	14	396	7.5e-92	303.3	COG3213	Uncharacterized protein involved in response to NO	396
2918746041	118	83.19	16	118	13	106	6.6e-28	91.4	COG2151	Metal-sulfur cluster biosynthetic enzyme	111
2918746042	155	90.67	1	148	1	136	6.1e-38	124.8	COG1959	DNA-binding transcriptional regulator, IscR family	150
2918746043	773	99.3	3	747	2	713	0.0e+00	953.8	COG3256	Nitric oxide reductase large subunit	717
2918746044	98	93.88	1	98	4	95	5.6e-31	101.2	COG4309	Uncharacterized conserved protein, DUF2249 family	98
2918746046	293	68.2	23	227	7	184	9.5e-32	104.6	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
2918746047	212	82.41	17	202	22	199	2.5e-22	74.2	COG0778	Nitroreductase	207
2918746048	800	85.58	12	596	92	744	9.8e-111	365.3	COG0209	Ribonucleotide reductase alpha subunit	696
2918746049	410	93.04	24	399	14	334	8.5e-68	223.6	COG2070	NAD(P)H-dependent flavin oxidoreductase YrpB, nitropropane dioxygenase family	336
2918746050	226	96.63	3	205	3	203	9.1e-54	176.9	COG0288	Carbonic anhydrase	207
2918746052	264	99.12	3	230	2	227	9.4e-79	258.9	COG2181	Nitrate reductase gamma subunit	228
2918746053	227	96.11	2	183	2	174	1.5e-48	159.4	COG2180	Nitrate reductase assembly protein NarJ, required for insertion of molybdenum cofactor	179
2918746054	510	98.64	1	510	1	506	0.0e+00	928.3	COG1140	Nitrate reductase beta subunit	513
2918746055	1262	100	1	1246	1	1242	0.0e+00	2114.4	COG5013	Nitrate reductase alpha subunit	1227
2918746056	550	49.52	27	282	2	209	8.3e-101	180.9	COG2223	Nitrate/nitrite transporter NarK	417
2918746056	550	55	276	549	177	407	8.3e-101	157.5	COG2223	Nitrate/nitrite transporter NarK	417
2918746057	441	95.95	15	437	6	408	2.5e-115	380.1	COG2223	Nitrate/nitrite transporter NarK	417
2918746058	216	62.67	11	208	21	203	4.2e-33	109.1	COG1284	Uncharacterized membrane-anchored protein YitT, contains DUF161 and DUF2179 domains	289
2918746059	158	68.75	25	137	38	136	2.3e-16	54.5	COG2703	Hemerythrin	144
2918746060	406	98.98	3	398	2	390	3.1e-82	271.7	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2918746061	214	92.06	1	191	7	180	1.2e-17	58.9	COG3945	Hemerythrin-like domain	189
2918746063	256	92.2	3	212	14	214	6.0e-21	69.5	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2918746066	276	63.82	103	275	72	198	1.4e-33	111.3	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
2918746067	2136	7.71	1550	1617	419	478	0.0e+00	17	COG5295	Autotransporter adhesin	715
2918746067	2136	7.84	525	606	437	497	0.0e+00	1.9	COG5295	Autotransporter adhesin	715
2918746067	2136	15.04	285	406	445	561	0.0e+00	2.3	COG5295	Autotransporter adhesin	715
2918746067	2136	16.45	1433	1563	459	586	0.0e+00	44.5	COG5295	Autotransporter adhesin	715
2918746067	2136	18.77	1980	2136	633	778	0.0e+00	138.8	COG5295	Autotransporter adhesin	715
2918746067	2136	21.85	357	531	417	586	0.0e+00	49.3	COG5295	Autotransporter adhesin	715
2918746067	2136	23.26	598	810	448	628	0.0e+00	39.2	COG5295	Autotransporter adhesin	715
2918746067	2136	24.55	1599	1799	493	683	0.0e+00	51.5	COG5295	Autotransporter adhesin	715
2918746067	2136	27.76	1032	1241	295	510	0.0e+00	8.4	COG5295	Autotransporter adhesin	715
2918746067	2136	28.53	1229	1451	397	618	0.0e+00	49.4	COG5295	Autotransporter adhesin	715
2918746067	2136	33.42	1745	1992	321	580	0.0e+00	29.6	COG5295	Autotransporter adhesin	715
2918746067	2136	50.51	762	1154	294	686	0.0e+00	51.6	COG5295	Autotransporter adhesin	715
2918746069	621	73.6	273	616	98	373	2.8e-47	156.5	COG4585	Signal transduction histidine kinase	365
2918746070	451	51.17	224	446	8	203	1.4e-22	33.9	COG0477	MFS family permease	338
2918746070	451	66.32	18	282	13	266	1.4e-22	43.5	COG0477	MFS family permease	338
2918746071	253	97.63	18	253	1	206	6.0e-65	213.1	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918746072	130	92.47	11	124	8	142	9.6e-07	22.8	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2918746073	180	67.03	6	172	38	159	1.8e-04	15.8	COG1514	2'-5' RNA ligase	180
2918746074	212	96.17	7	212	4	204	1.8e-27	92	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918746075	297	97.07	1	296	4	301	1.1e-52	173.5	COG0492	Thioredoxin reductase	305
2918746076	281	97.97	4	281	4	292	4.4e-32	106.6	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918746077	293	79.93	1	269	9	231	2.1e-20	68.3	COG0500	SAM-dependent methyltransferase	257
2918746078	268	90.3	1	244	3	244	4.7e-53	175.1	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918746079	153	78.31	1	153	37	184	4.8e-29	96.3	COG2020	Protein-S-isoprenylcysteine O-methyltransferase Ste14	187
2918746081	358	97.25	1	358	6	358	5.9e-104	342.8	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
2918746082	266	95.09	2	262	3	254	1.9e-75	248	COG0300	Short-chain dehydrogenase	265
2918746083	176	94.74	34	165	4	129	2.7e-15	51.1	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918746084	117	85.19	1	117	1	115	1.5e-30	100.6	COG3791	Uncharacterized conserved protein	133
2918746085	686	98.35	5	685	8	724	0.0e+00	483.2	COG0480	Translation elongation factor EF-G, a GTPase	697
2918746086	545	96.71	10	514	2	501	0.0e+00	441.9	COG0366	Glycosidase	505
2918746087	762	95.22	201	758	12	549	2.5e-38	123.3	COG2936	Predicted acyl esterase	563
2918746088	586	95.39	1	586	15	593	0.0e+00	473.8	COG4178	ABC-type uncharacterized transport system, permease and ATPase components	604
2918746089	466	6.73	45	106	268	309	6.4e-23	12.3	COG3387	Glucoamylase (glucan-1,4-alpha-glucosidase), GH15 family	612
2918746089	466	34.13	193	458	404	616	6.4e-23	61.9	COG3387	Glucoamylase (glucan-1,4-alpha-glucosidase), GH15 family	612
2918746090	432	94.46	3	432	10	435	2.4e-108	356.4	COG5368	Uncharacterized protein	451
2918746091	714	93.29	11	481	1	389	3.7e-96	317	COG1472	Periplasmic beta-glucosidase and related glycosidases	397
2918746093	87	61.63	1	70	3	55	4.2e-09	30.8	COG2161	Antitoxin component YafN of the YafNO toxin-antitoxin module, PHD/YefM family	86
2918746094	111	53.44	2	111	46	115	1.8e-10	35.6	COG1917	Cupin domain protein related to quercetin dioxygenase	131
2918746095	381	97.59	10	380	5	368	6.1e-73	240.2	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
2918746096	241	97.91	1	239	5	238	3.1e-48	159	COG2188	DNA-binding transcriptional regulator, GntR family	236
2918746097	256	96.51	1	256	7	255	1.6e-74	245.3	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2918746098	271	97.61	7	263	4	248	5.9e-93	305.4	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2918746099	334	96.72	1	334	5	328	1.5e-43	144.1	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918746100	537	97.01	1	536	7	557	0.0e+00	436.5	COG2303	Choline dehydrogenase or related flavoprotein	542
2918746101	431	96.83	85	404	9	313	2.8e-90	296.9	COG0540	Aspartate carbamoyltransferase, catalytic chain	316
2918746102	403	98.5	1	402	6	400	3.4e-129	425.9	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2918746104	319	98.12	3	316	5	317	3.2e-88	290.4	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918746105	292	91.59	1	289	17	299	5.0e-66	217.5	COG3386	Sugar lactone lactonase YvrE	307
2918746106	523	92.47	67	513	33	425	4.3e-116	383.2	COG0840	Methyl-accepting chemotaxis protein	408
2918746107	1074	65.91	540	1074	212	648	1.0e-124	411.5	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2918746108	139	95.07	1	138	2	136	5.7e-21	69.8	COG1569	Predicted nucleic acid-binding protein, contains PIN domain	142
2918746111	302	98.01	3	302	3	297	2.6e-68	225.6	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918746112	363	93	7	341	16	334	1.9e-55	182.8	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2918746113	311	87.57	6	181	10	171	1.6e-46	152.2	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
2918746114	386	95.99	4	386	12	394	2.2e-75	248.8	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918746115	369	90.23	8	361	10	369	2.6e-30	100.2	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918746116	253	97.74	1	250	7	265	7.7e-69	226.6	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918746117	710	99.68	7	629	2	633	0.0e+00	487.6	COG1042	Acyl-CoA synthetase (NDP forming)	598
2918746118	252	99.25	3	249	1	266	9.7e-61	200.3	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918746119	126	86.61	6	122	15	124	3.3e-11	37.9	COG3324	Predicted enzyme related to lactoylglutathione lyase	127
2918746121	412	8.96	349	380	173	196	1.1e-45	6.5	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918746121	412	97.39	1	239	6	266	1.1e-45	147.4	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918746122	329	96.24	6	328	11	317	1.5e-83	275.1	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918746123	1161	96.5	525	1161	24	658	2.3e-32	107.3	COG3468	Type V secretory pathway, adhesin AidA	644
2918746124	320	84.09	177	313	11	121	2.8e-26	86.1	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918746125	216	96.15	48	216	3	152	3.5e-67	219.5	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
2918746126	316	98.6	1	316	1	282	3.2e-98	323.5	COG1319	CO or xanthine dehydrogenase, FAD-binding subunit	284
2918746127	736	99.6	13	733	2	743	0.0e+00	677.2	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
2918746132	110	53.08	16	107	2	70	7.6e-10	34.5	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918746135	152	94.87	1	151	5	152	9.8e-56	182.3	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
2918746136	726	8.86	65	157	456	521	4.6e-61	16.8	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
2918746136	726	15.44	167	280	5	119	4.6e-61	21.8	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
2918746136	726	15.84	249	420	172	289	4.6e-61	49.3	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
2918746136	726	27.92	508	705	527	734	4.6e-61	116.6	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
2918746137	230	93.12	7	219	13	215	5.5e-21	69.7	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2918746138	596	15.31	445	504	147	178	3.0e-04	2.7	COG0400	Predicted esterase	207
2918746138	596	25.84	197	283	93	146	3.0e-04	9.6	COG0400	Predicted esterase	207
2918746140	740	8.01	66	166	83	132	3.8e-123	2.6	COG3914	Predicted O-linked N-acetylglucosamine transferase, SPINDLY family	620
2918746140	740	75.48	180	729	153	623	3.8e-123	401.8	COG3914	Predicted O-linked N-acetylglucosamine transferase, SPINDLY family	620
2918746144	599	6.33	472	518	8	36	4.4e-86	6.9	COG0493	NADPH-dependent glutamate synthase beta chain or related oxidoreductase	457
2918746144	599	92.58	10	426	32	455	4.4e-86	276.7	COG0493	NADPH-dependent glutamate synthase beta chain or related oxidoreductase	457
2918746145	639	96.07	231	636	3	369	9.7e-65	213.6	COG0674	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, alpha subunit	365
2918746145	639	96.57	33	223	3	199	1.7e-24	80.5	COG1014	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, gamma subunit	203
2918746146	351	72.24	17	292	10	225	7.8e-54	177.4	COG1013	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, beta subunit	294
2918746147	145	94.48	1	123	9	162	4.0e-23	77.1	COG0517	CBS domain	117
2918746148	366	98.39	2	364	3	369	4.6e-85	280.1	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
2918746149	310	98.67	6	304	1	297	3.5e-51	169.4	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918746150	364	99.13	23	360	2	341	8.1e-79	259.6	COG2008	Threonine aldolase	342
2918746151	326	98.12	6	323	5	317	5.4e-79	260.1	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918746152	542	85.28	114	536	56	391	8.7e-62	204.7	COG0642	Signal transduction histidine kinase	336
2918746153	229	98.71	3	228	2	230	4.2e-84	276.1	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918746154	161	93.63	4	158	9	155	1.7e-73	239.7	COG4875	Uncharacterized protein	156
2918746155	152	87.26	5	151	7	143	6.9e-22	72.7	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
2918746156	115	69.49	2	105	19	100	5.3e-10	34.4	COG0640	DNA-binding transcriptional regulator, ArsR family	110
2918746157	229	97.67	4	210	1	210	3.2e-43	142.6	COG0625	Glutathione S-transferase	211
2918746158	244	99.17	1	242	2	241	1.9e-110	362.3	COG1126	ABC-type polar amino acid transport system, ATPase component	240
2918746159	416	97.61	11	416	9	416	2.9e-72	238.6	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
2918746160	979	10.31	116	172	3	42	2.4e-70	25.4	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918746160	979	20.88	170	336	159	239	2.4e-70	5.3	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918746160	979	80.95	490	552	4	54	5.1e-03	10.5	COG2906	Bacterioferritin-associated ferredoxin	63
2918746160	979	97.68	598	979	4	382	2.4e-70	212.3	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918746161	298	97.99	1	295	2	294	2.5e-89	293.5	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
2918746162	276	94.7	1	267	5	272	3.5e-36	119.4	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918746163	239	92.54	4	222	18	228	1.7e-75	248.1	COG0765	ABC-type amino acid transport system, permease component	222
2918746164	486	98.61	6	463	2	426	4.8e-108	356.3	COG0044	Dihydroorotase or related cyclic amidohydrolase	430
2918746165	228	92.24	11	228	11	224	1.1e-50	166.9	COG1802	DNA-binding transcriptional regulator, GntR family	230
2918746168	98	75.96	1	92	19	97	1.3e-22	74.1	COG3093	Plasmid maintenance system antidote protein VapI, contains XRE-type HTH domain	104
2918746169	89	96.81	1	89	2	92	5.5e-14	46.7	COG3549	Plasmid maintenance system killer protein	94
2918746174	664	99.69	6	654	2	645	0.0e+00	788.8	COG4770	Acetyl/propionyl-CoA carboxylase, alpha subunit	645
2918746175	539	98.1	12	538	4	519	0.0e+00	518.9	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component	526
2918746177	286	80.95	160	238	10	77	2.8e-15	51.4	COG2770	HAMP domain	83
2918746178	181	39.85	1	164	218	374	7.0e-38	125.9	COG0642	Signal transduction histidine kinase	336
2918746179	118	40.95	9	116	77	171	2.4e-22	73.9	COG3039	Transposase and inactivated derivatives, IS5 family	230
2918746180	230	98.71	2	228	2	230	3.0e-76	250.4	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918746181	528	82.74	155	528	66	391	5.6e-59	195.5	COG0642	Signal transduction histidine kinase	336
2918746184	226	98.71	2	225	2	230	1.8e-62	205.3	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918746185	788	98.45	1	788	13	774	0.0e+00	694.2	COG4775	Outer membrane protein assembly factor BamA	766
2918746187	385	99.44	1	385	3	360	5.5e-53	174.9	COG3203	Outer membrane protein (porin)	354
2918746189	152	75.54	7	114	10	114	8.9e-08	24	COG3415	Transposase	138
2918746190	568	11.33	159	250	247	280	3.3e-28	3.3	COG4974	Site-specific recombinase XerD	300
2918746190	568	88	227	562	23	286	3.3e-28	89.1	COG4974	Site-specific recombinase XerD	300
2918746195	67	13.18	1	67	71	104	1.0e-03	13.3	COG1684	Flagellar biosynthesis protein FliR	258
2918746202	445	96.41	11	436	14	389	1.3e-28	94.7	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918746203	584	94.48	2	563	21	568	0.0e+00	623.3	COG4618	ABC-type protease/lipase transport system, ATPase and permease components	580
2918746204	1805	15.91	974	1041	200	241	9.5e-07	3.7	COG5266	Uncharacterized conserved protein, contains GH25 family domain	264
2918746204	1805	16.67	651	717	200	243	9.5e-07	2.8	COG5266	Uncharacterized conserved protein, contains GH25 family domain	264
2918746204	1805	17.8	866	933	200	246	9.5e-07	1.7	COG5266	Uncharacterized conserved protein, contains GH25 family domain	264
2918746204	1805	21.97	1083	1152	201	258	9.5e-07	2.4	COG5266	Uncharacterized conserved protein, contains GH25 family domain	264
2918746204	1805	22.73	537	608	199	258	9.5e-07	6.7	COG5266	Uncharacterized conserved protein, contains GH25 family domain	264
2918746204	1805	23.11	756	826	199	259	9.5e-07	5.5	COG5266	Uncharacterized conserved protein, contains GH25 family domain	264
2918746204	1805	28.57	1	180	377	536	1.2e-34	55.6	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918746204	1805	52.5	1507	1799	265	558	1.2e-34	75.3	COG2931	Ca2+-binding protein, RTX toxin-related	510
2918746205	147	77.78	1	110	7	97	3.4e-11	38.1	COG2963	Transposase and inactivated derivatives	116
2918746207	160	54.93	1	157	126	281	6.5e-40	131.9	COG2801	Transposase InsO and inactivated derivatives	232
2918746208	48	8.13	1	46	328	367	1.7e-13	45	COG1793	ATP-dependent DNA ligase	444
2918746209	45	14.93	1	43	228	267	1.1e-06	23.1	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918746212	167	87.97	15	148	6	122	9.8e-16	52.5	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918746213	291	79.72	1	254	53	276	3.9e-47	155.8	COG3000	Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily	271
2918746214	304	96.35	9	303	2	291	4.0e-45	149.4	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918746215	457	38.3	3	192	285	469	8.4e-15	22.9	COG0471	Di- and tricarboxylate transporter	461
2918746215	457	40.58	260	457	285	480	8.4e-15	32	COG0471	Di- and tricarboxylate transporter	461
2918746217	110	79.59	24	109	8	85	2.0e-06	22.6	COG3052	Citrate lyase, gamma subunit	98
2918746218	293	32.32	3	234	43	212	3.7e-23	76.3	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component	526
2918746221	287	94.83	15	284	8	282	1.5e-48	160	COG1767	Triphosphoribosyl-dephospho-CoA synthetase	288
2918746222	302	5.88	1	34	3	22	4.9e-38	3.8	COG0331	Malonyl CoA-acyl carrier protein transacylase	310
2918746222	302	72.65	49	295	79	325	4.9e-38	122.3	COG0331	Malonyl CoA-acyl carrier protein transacylase	310
2918746223	309	98.01	2	298	2	296	3.6e-67	222	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918746224	270	89.93	1	246	4	244	6.9e-53	174.6	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918746225	1025	99.9	7	1015	1	1013	0.0e+00	894.3	COG0841	Multidrug efflux pump subunit AcrB	1009
2918746226	371	97.18	1	361	8	386	1.1e-45	151.1	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918746227	205	80.86	6	204	5	173	8.1e-24	80.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918746228	489	98.48	12	484	2	454	1.8e-98	325	COG1538	Outer membrane protein TolC	457
2918746229	170	84.21	37	166	5	116	2.3e-13	45	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918746230	196	91.87	1	191	12	203	4.7e-21	71.2	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918746231	394	99.49	1	394	1	392	6.1e-112	369.2	COG0183	Acetyl-CoA acetyltransferase	392
2918746232	592	97.24	10	460	7	394	6.4e-104	343.1	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918746233	328	97.39	1	321	3	338	1.6e-84	278.8	COG2070	NAD(P)H-dependent flavin oxidoreductase YrpB, nitropropane dioxygenase family	336
2918746234	246	91.42	4	240	5	249	4.1e-33	109.8	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918746235	196	96.06	1	196	6	200	6.1e-66	216.7	COG3917	2-hydroxychromene-2-carboxylate isomerase	203
2918746236	546	96.13	19	546	11	556	0.0e+00	433.4	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2918746237	236	89.47	60	236	10	179	2.6e-53	175	COG3703	Cation transport regulator ChaC	190
2918746238	304	97.67	6	303	1	294	3.1e-45	149.9	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918746239	421	99.2	16	418	3	375	3.6e-85	281.1	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
2918746240	156	98.17	1	156	2	162	8.5e-38	124.7	COG5517	3-phenylpropionate/cinnamic acid dioxygenase, small subunit	164
2918746241	105	97.2	2	105	3	106	1.7e-30	99.8	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
2918746242	405	83.02	6	385	1	357	6.5e-73	241.1	COG0446	NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase	415
2918746243	455	98.5	4	455	6	465	0.0e+00	535.2	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2918746244	611	97.52	20	597	15	603	0.0e+00	527.6	COG4191	Signal transduction histidine kinase regulating C4-dicarboxylate transport system	603
2918746245	251	98.51	3	250	4	267	2.1e-70	232.1	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918746246	448	97.37	7	430	4	410	0.0e+00	524.5	COG1301	Na+/H+-dicarboxylate symporter	415
2918746249	332	97.18	8	330	9	318	1.3e-76	252.4	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918746250	297	98.01	1	296	1	295	1.1e-50	167.7	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918746253	449	97.09	2	448	7	473	9.5e-111	365.7	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
2918746255	466	97.89	84	466	6	376	2.2e-100	331.1	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
2918746256	209	88.7	1	170	7	163	7.5e-19	62.3	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
2918746257	357	83.43	1	313	3	279	1.9e-41	137	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
2918746259	305	96.35	1	293	1	290	1.5e-57	190.3	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918746260	458	50.13	244	452	4	195	5.0e-37	29.3	COG0477	MFS family permease	338
2918746260	458	54.83	17	239	5	214	5.0e-37	99.5	COG0477	MFS family permease	338
2918746261	325	97.7	3	325	5	301	1.7e-62	206.3	COG2159	Predicted metal-dependent hydrolase, TIM-barrel fold	293
2918746262	289	82.46	50	274	3	190	7.4e-38	124.8	COG3485	Protocatechuate 3,4-dioxygenase beta subunit	226
2918746263	353	98.94	4	346	5	379	2.5e-76	249	COG1454	Alcohol dehydrogenase, class IV	377
2918746264	317	98.01	6	307	1	295	1.4e-43	144.3	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918746265	154	90.23	19	149	8	127	7.0e-22	72.4	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918746266	397	92.48	7	395	29	397	2.5e-32	104.3	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918746267	185	87.57	8	181	8	169	1.3e-41	136.8	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
2918746268	289	97.34	6	289	3	295	2.5e-54	179.8	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918746269	303	95.02	11	300	11	296	3.7e-42	139.2	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918746270	132	87.5	3	124	15	133	1.1e-35	117.1	COG3474	Cytochrome c2	135
2918746271	189	12.92	46	115	26	48	2.4e-09	9.6	COG1633	Rubrerythrin	176
2918746271	189	33.15	118	185	21	79	2.4e-09	19.3	COG1633	Rubrerythrin	176
2918746272	241	95.7	19	209	3	180	2.5e-42	139.1	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918746273	283	64.06	14	221	2	222	1.4e-29	98	COG2070	NAD(P)H-dependent flavin oxidoreductase YrpB, nitropropane dioxygenase family	336
2918746274	506	99.4	2	506	1	501	0.0e+00	678.6	COG3333	TctA family transporter	504
2918746276	138	72.93	11	132	14	110	6.6e-18	59.6	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918746277	585	96.85	5	439	10	440	1.2e-96	318.6	COG0038	H+/Cl- antiporter ClcA	443
2918746280	280	91.87	5	262	16	275	1.1e-51	170.3	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918746281	244	98.76	1	242	2	240	1.1e-110	363.2	COG1126	ABC-type polar amino acid transport system, ATPase component	240
2918746282	252	93.42	6	229	15	227	1.4e-68	225.6	COG0765	ABC-type amino acid transport system, permease component	222
2918746283	233	92.98	2	231	15	226	5.9e-67	220.3	COG0765	ABC-type amino acid transport system, permease component	222
2918746284	250	97.97	1	237	4	244	1.7e-76	251.8	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
2918746285	254	96.83	1	250	2	245	2.1e-97	319.9	COG1540	Lactam utilization protein B (function unknown)	252
2918746286	131	51.7	29	130	71	146	5.6e-14	47.8	COG0511	Biotin carboxyl carrier protein	140
2918746287	331	99.05	2	322	1	313	2.1e-110	363.3	COG1984	Allophanate hydrolase subunit 2	314
2918746288	222	92.07	8	221	2	210	2.6e-70	230.8	COG2049	Allophanate hydrolase subunit 1	223
2918746289	450	69.35	1	450	1	448	0.0e+00	656.6	COG4770	Acetyl/propionyl-CoA carboxylase, alpha subunit	645
2918746290	144	97.96	6	144	1	144	1.7e-31	104.6	COG0511	Biotin carboxyl carrier protein	140
2918746291	312	97.67	1	298	2	295	1.5e-59	196.9	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918746292	402	98.99	8	402	2	393	1.1e-120	398	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
2918746293	223	93.87	6	223	11	209	2.6e-61	201.6	COG0684	Regulator of RNase E activity RraA	210
2918746295	324	98.12	2	322	3	315	3.8e-80	263.9	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918746296	318	97.81	1	316	6	317	5.2e-96	316.1	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918746297	458	98.54	10	453	7	480	9.7e-115	378.6	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
2918746298	222	91.98	8	218	14	208	7.6e-46	151	COG0684	Regulator of RNase E activity RraA	210
2918746299	317	98.34	11	304	2	297	1.2e-53	177.4	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918746300	324	96.24	4	319	10	316	1.1e-71	236.2	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918746301	353	98.28	1	347	4	346	5.1e-71	234	COG2055	Malate/lactate/ureidoglycolate dehydrogenase, LDH2 family	349
2918746302	296	97.01	2	296	2	293	3.0e-60	199.2	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918746303	612	89.73	23	593	21	527	2.7e-88	287.9	COG2936	Predicted acyl esterase	563
2918746304	330	97.81	2	328	6	317	4.8e-83	273.4	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918746305	327	96.87	1	325	8	316	2.1e-90	297.7	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918746307	341	98.67	1	296	1	297	1.0e-57	190.7	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918746308	338	96.61	34	333	6	290	1.1e-18	62.2	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918746309	264	75.76	132	261	22	121	1.5e-21	70.9	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918746310	181	50.96	1	161	6	85	7.3e-09	30.3	COG1225	Peroxiredoxin	157
2918746313	109	56.16	30	106	64	145	2.1e-11	37.8	COG0071	Molecular chaperone IbpA, HSP20 family	146
2918746314	185	97.96	8	184	4	195	1.6e-49	163	COG0693	Putative intracellular protease/amidase	188
2918746315	139	98.77	2	119	2	162	5.7e-24	79.6	COG0517	CBS domain	117
2918746316	168	25.77	2	167	161	260	7.9e-01	3.1	COG3064	Membrane protein involved in colicin uptake	387
2918746317	455	95.41	1	455	18	474	0.0e+00	476.1	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918746318	169	80.45	47	163	8	114	1.5e-13	45.3	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918746319	93	23.85	7	93	117	194	9.2e-04	13.1	COG3173	Predicted  kinase, aminoglycoside phosphotransferase (APT) family	321
2918746320	394	87.69	149	394	1	235	8.4e-71	232.9	COG1018	Ferredoxin-NADP reductase	266
2918746320	394	98.67	1	149	2	149	1.7e-60	197.9	COG1017	Hemoglobin-like flavoprotein	150
2918746321	526	89.64	4	522	53	545	0.0e+00	533.9	COG3604	Transcriptional regulator containing GAF, AAA-type ATPase, and DNA-binding Fis domains	550
2918746322	230	81.79	1	224	51	279	8.2e-43	141.6	COG3618	Predicted metal-dependent hydrolase, TIM-barrel fold	279
2918746323	329	95.3	9	327	12	315	5.3e-95	312.7	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918746325	292	95.02	1	290	6	291	3.6e-52	172.6	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918746326	114	90.91	5	114	7	106	9.8e-32	104	COG4654	Cytochrome c551/c552	110
2918746327	756	95.84	29	756	25	738	0.0e+00	451	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
2918746328	157	95.51	1	157	5	153	5.2e-60	196.4	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
2918746329	316	61.89	37	312	83	298	1.2e-11	36.5	COG5397	Uncharacterized protein	349
2918746331	228	12.6	150	203	182	214	2.3e-09	9.2	COG3823	Glutamine cyclotransferase	262
2918746331	228	13.36	113	156	181	215	2.3e-09	10.2	COG3823	Glutamine cyclotransferase	262
2918746331	228	29.77	9	108	135	212	2.3e-09	7	COG3823	Glutamine cyclotransferase	262
2918746332	265	97.92	5	249	4	238	2.6e-99	326.3	COG4312	Predicted dithiol-disulfide oxidoreductase, DUF899 family	247
2918746334	305	89.25	3	179	11	176	8.0e-44	143.8	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918746335	253	89.55	2	239	4	243	3.2e-27	90.3	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918746336	415	38.38	256	413	51	197	5.3e-32	50.2	COG0477	MFS family permease	338
2918746336	415	80.16	13	275	8	314	5.3e-32	59.9	COG0477	MFS family permease	338
2918746337	325	96.87	1	324	10	318	5.0e-71	234.1	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918746338	341	18.62	228	341	301	370	1.1e-42	7.6	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
2918746338	341	46.28	1	220	24	197	1.1e-42	135.6	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
2918746339	268	71.25	203	268	17	73	1.6e-11	35.7	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2918746340	161	91.67	26	161	10	141	1.1e-25	85.3	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
2918746342	280	95.74	2	280	5	274	1.2e-94	311.3	COG3220	Uncharacterized conserved protein, UPF0276 family	282
2918746343	95	84.62	1	94	15	102	1.5e-34	113	COG5572	Uncharacterized membrane protein	104
2918746345	410	86.74	8	401	44	442	9.5e-17	55.4	COG1538	Outer membrane protein TolC	457
2918746346	500	12.82	1	160	47	96	4.7e-32	11.9	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918746346	500	52.05	174	411	180	382	4.7e-32	94.7	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918746347	1048	99.51	1	1042	1	1025	0.0e+00	1364.6	COG3696	Cu/Ag efflux pump CusA	1027
2918746348	340	60.6	44	333	102	304	1.3e-12	42.7	COG0582	Integrase	309
2918746349	124	98.32	7	124	2	118	1.3e-31	103.9	COG2832	Uncharacterized membrane protein YbaN, DUF454 family	119
2918746351	190	93.01	5	174	5	177	1.9e-40	133	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918746353	404	99.37	157	317	1	158	1.5e-63	207.8	COG4804	Predicted nuclease of restriction endonuclease-like (RecB) superfamily,  DUF1016 family	159
2918746354	727	98.99	7	727	9	795	1.7e-72	239.9	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2918746355	592	9.8	402	550	353	411	0.0e+00	20.4	COG0514	Superfamily II DNA helicase RecQ	590
2918746355	592	58.64	17	409	4	356	0.0e+00	451.6	COG0514	Superfamily II DNA helicase RecQ	590
2918746356	162	87.5	2	148	14	153	3.3e-25	83.4	COG4244	Uncharacterized membrane protein	160
2918746357	147	86.52	1	137	2	123	2.9e-45	148	COG5478	Low affinity Fe/Cu permease	141
2918746359	52	14.38	1	52	252	294	5.8e-06	20.1	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
2918746361	451	98.66	14	421	4	371	7.7e-84	276.3	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
2918746362	478	98.54	4	478	2	473	0.0e+00	527.5	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918746363	417	90.89	16	415	34	392	8.4e-17	54.9	COG2814	Predicted arabinose efflux permease, MFS family	394
2918746364	341	98.67	5	307	2	298	2.3e-51	169.9	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918746365	516	87.44	306	510	23	217	1.3e-66	218.2	COG1174	ABC-type proline/glycine betaine transport system, permease component	221
2918746365	516	95.67	4	290	12	298	1.4e-78	258.5	COG1732	Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)	300
2918746366	350	38.06	32	183	184	301	9.6e-09	6.3	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
2918746366	350	43.87	178	349	8	143	9.6e-09	21.6	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
2918746367	509	98.04	14	508	1	451	3.8e-104	343.6	COG1538	Outer membrane protein TolC	457
2918746368	372	72.35	102	371	77	288	5.8e-32	105.6	COG0842	ABC-type multidrug transport system, permease component	286
2918746369	373	83.28	87	373	45	288	6.8e-31	102	COG0842	ABC-type multidrug transport system, permease component	286
2918746370	586	77.12	1	305	12	247	0.0e+00	254.4	COG1131	ABC-type multidrug transport system, ATPase component	293
2918746370	586	78.43	332	585	4	243	0.0e+00	275	COG1131	ABC-type multidrug transport system, ATPase component	293
2918746371	341	76.42	1	304	19	287	3.5e-47	155.2	COG1566	Multidrug resistance efflux pump	352
2918746372	241	92.82	7	227	11	204	1.2e-22	76.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918746373	459	74.85	53	452	64	426	6.4e-64	210.8	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
2918746374	221	95.81	3	210	2	207	4.0e-39	129.3	COG0625	Glutathione S-transferase	211
2918746375	373	97.58	6	368	6	328	8.3e-66	216.8	COG0620	Methionine synthase II (cobalamin-independent)	330
2918746376	257	93.53	3	244	13	229	2.0e-54	179.1	COG1802	DNA-binding transcriptional regulator, GntR family	230
2918746377	391	96.99	18	381	4	358	2.5e-49	162.7	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918746378	290	97.67	1	290	5	298	7.7e-78	256.7	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2918746379	327	93.81	12	318	12	314	3.8e-67	221.3	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918746380	253	99.21	1	247	2	253	5.6e-87	285.9	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2918746381	234	99.58	2	232	2	237	1.6e-82	270.9	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2918746383	243	97.64	9	222	2	208	7.1e-80	262.1	COG3531	Predicted protein-disulfide isomerase , contains CxxC motif	212
2918746384	294	77.69	19	281	30	231	1.0e-24	82.1	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2918746385	305	98.67	4	304	1	297	1.7e-52	173.8	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918746386	315	63.92	9	290	6	269	1.3e-43	144	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
2918746387	401	98.5	1	400	6	400	3.1e-123	406.4	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2918746388	328	95.92	8	327	12	317	7.5e-80	263.1	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918746389	104	97.17	1	104	2	104	1.8e-38	126	COG2076	Multidrug transporter EmrE and related cation transporters	106
2918746390	376	94.5	3	375	14	374	5.3e-120	395	COG3448	CBS-domain-containing membrane protein	382
2918746391	411	51.96	217	410	4	202	2.0e-35	16.8	COG0477	MFS family permease	338
2918746391	411	62.66	10	246	7	246	2.0e-35	102.3	COG0477	MFS family permease	338
2918746392	733	21.41	142	274	44	116	5.5e-129	6.6	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
2918746392	733	99.12	365	731	4	341	5.5e-129	419.9	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
2918746393	659	72.48	2	651	2	433	0.0e+00	503.6	COG0358	DNA primase (bacterial type)	568
2918746394	313	90.76	8	309	14	288	6.8e-40	131.6	COG1295	Uncharacterized membrane protein, BrkB/YihY/UPF0761 family (not an RNase)	303
2918746395	252	99.25	1	248	1	266	2.3e-49	163.1	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918746396	183	66.46	2	115	48	152	3.6e-05	18.8	COG5490	Uncharacterized protein	158
2918746397	308	86.46	1	306	9	308	5.8e-77	253.6	COG0123	Acetoin utilization deacetylase AcuC or a related deacetylase	340
2918746398	147	91.37	13	147	10	136	1.1e-31	104.4	COG0824	Acyl-CoA thioesterase FadM	137
2918746399	137	64.6	18	137	53	156	5.1e-02	6.9	COG0711	FoF1-type ATP synthase, membrane subunit b or b'	161
2918746400	77	94.03	1	65	4	66	2.0e-25	83.4	COG3237	Uncharacterized conserved protein YjbJ, UPF0337 family	67
2918746401	406	90.49	1	406	10	380	3.5e-104	343.4	COG1488	Nicotinic acid phosphoribosyltransferase	405
2918746402	470	99.53	30	470	3	424	2.8e-77	254.8	COG1055	Na+/H+ antiporter NhaD or related arsenite permease	424
2918746403	328	99.08	2	322	2	325	4.6e-105	345.8	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
2918746404	456	82.63	17	455	51	421	1.6e-104	344.7	COG1322	DNA anti-recombination protein (rearrangement mutator) RmuC	448
2918746405	387	48.56	207	386	4	189	6.7e-24	31.2	COG0477	MFS family permease	338
2918746405	387	49.61	6	222	23	212	6.7e-24	53.5	COG0477	MFS family permease	338
2918746406	297	91.22	65	297	10	196	1.2e-63	208.9	COG1611	Predicted Rossmann fold nucleotide-binding protein	205
2918746407	259	96.23	1	259	4	258	2.7e-64	211.9	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918746408	184	98.47	1	128	3	131	3.4e-41	134.6	COG0231	Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)	131
2918746409	365	97.57	1	364	3	363	1.6e-86	285.3	COG4394	Uncharacterized protein	370
2918746410	485	95.69	41	485	17	416	4.4e-62	205.1	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
2918746411	684	97.8	80	680	12	544	0.0e+00	561.5	COG0405	Gamma-glutamyltranspeptidase	539
2918746412	653	99.5	5	652	4	598	0.0e+00	718.3	COG0322	Excinuclease UvrABC, nuclease subunit	581
2918746413	188	93.3	1	187	12	192	4.1e-48	158.8	COG0558	Phosphatidylglycerophosphate synthase	192
2918746414	294	94.68	9	294	12	296	2.0e-39	130.3	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918746415	320	98.67	6	311	1	297	1.7e-57	190.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918746416	304	97.97	9	296	5	293	5.5e-32	106.3	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918746417	361	99.14	1	361	1	345	1.8e-125	413.2	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
2918746418	90	95.74	1	90	2	91	3.1e-34	111.9	COG0776	Bacterial nucleoid DNA-binding protein	94
2918746420	637	25.23	8	160	9	90	1.9e-40	1.6	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
2918746420	637	62.46	202	429	120	322	1.9e-40	132.7	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
2918746421	224	94.74	1	220	2	199	1.2e-27	91.6	COG0406	Broad specificity phosphatase PhoE	208
2918746423	82	97.56	1	82	1	80	3.4e-19	63.6	COG2261	Uncharacterized membrane protein YeaQ/YmgE, transglycosylase-associated protein family	82
2918746424	230	93.3	37	212	12	178	3.3e-33	109.4	COG1881	Uncharacterized conserved protein, phosphatidylethanolamine-binding protein (PEBP) family	174
2918746426	114	94.53	1	114	8	128	1.4e-18	62.4	COG2916	DNA-binding protein H-NS	128
2918746427	299	90.33	1	298	31	329	3.8e-89	293.9	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2918746428	252	97.66	1	248	1	250	1.5e-83	274.9	COG0496	Broad specificity polyphosphatase and 5'/3'-nucleotidase SurE	252
2918746429	257	94.79	43	257	4	203	1.7e-64	211.9	COG2518	Protein-L-isoaspartate O-methyltransferase	209
2918746430	283	95.89	56	283	3	305	4.5e-45	149.2	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
2918746431	333	80.35	31	333	66	339	8.5e-87	286.4	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
2918746432	482	98.39	20	475	8	436	3.4e-100	330.4	COG2265	tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family	432
2918746433	233	92.67	2	232	17	231	4.3e-47	155.2	COG0670	Integral membrane protein, interacts with FtsH	233
2918746434	135	97.16	1	135	2	138	1.8e-41	136.4	COG3193	Uncharacterized conserved protein GlcG, DUF336 family	141
2918746435	70	69.84	12	70	20	63	6.9e-17	56.2	COG4256	Hemin uptake protein HemP	63
2918746436	137	98.56	1	137	1	137	2.0e-44	145.7	COG0848	Biopolymer transport protein ExbD	137
2918746437	238	97.22	10	224	2	211	2.6e-55	182.5	COG0811	Biopolymer transport protein ExbB/TolQ	216
2918746438	232	77.01	2	232	63	273	1.0e-17	58.2	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
2918746440	739	95.6	2	739	32	748	2.7e-112	370.7	COG4774	Outer membrane receptor for monomeric catechols	750
2918746441	228	98.69	1	228	3	228	1.4e-89	294.3	COG3128	Predicted 2-oxoglutarate- and Fe(II)-dependent dioxygenase YbiX	229
2918746442	99	71.84	1	97	24	97	4.3e-09	31.3	COG5591	Uncharacterized protein	103
2918746443	184	94.79	4	183	4	185	1.7e-41	135.6	COG3658	Cytochrome b	192
2918746444	158	98.73	1	157	1	155	2.1e-71	233.6	COG2193	Bacterioferritin (cytochrome b1)	157
2918746445	190	95.83	1	190	2	185	1.6e-71	234.5	COG0450	Alkyl hydroperoxide reductase subunit AhpC (peroxiredoxin)	194
2918746446	523	99.23	1	518	1	517	0.0e+00	894.1	COG3634	Alkyl hydroperoxide reductase subunit AhpF	520
2918746447	273	98.9	1	273	1	270	2.4e-94	310.6	COG1806	Regulator of PEP synthase PpsR, kinase-PPPase family (combines ADP:protein kinase and phosphorylase activities)	273
2918746448	797	99.11	7	797	3	782	0.0e+00	900.7	COG0574	Phosphoenolpyruvate synthase/pyruvate phosphate dikinase	740
2918746450	124	98.21	2	113	1	110	3.2e-41	134.4	COG0360	Ribosomal protein S6	112
2918746451	105	90.29	8	105	4	96	7.6e-17	56	COG2965	Primosomal replication protein N	103
2918746452	93	96.2	8	85	3	78	1.8e-29	96.7	COG0238	Ribosomal protein S18	75
2918746453	150	98.65	1	149	1	146	2.2e-51	168.6	COG0359	Ribosomal protein L9	148
2918746454	469	99.77	22	462	1	435	0.0e+00	560.8	COG0305	Replicative DNA helicase	435
2918746455	237	70.93	1	236	4	225	7.2e-68	224	COG2378	Predicted DNA-binding transcriptional regulator YafY, contains an HTH and WYL domains	311
2918746456	155	92.36	7	154	1	145	1.8e-16	55.3	COG3708	Predicted transcriptional regulator YdeE, contains AraC-type DNA-binding domain	157
2918746458	123	93.7	1	123	6	124	3.1e-34	112.8	COG3324	Predicted enzyme related to lactoylglutathione lyase	127
2918746459	594	99.77	126	594	2	440	0.0e+00	527.7	COG1875	Predicted ribonuclease YlaK, contains NYN-type RNase and PhoH-family ATPase domains	436
2918746460	193	97.45	35	191	4	156	4.8e-52	170.5	COG1225	Peroxiredoxin	157
2918746461	126	94.49	1	121	7	126	2.9e-28	93.4	COG3737	Uncharacterized conserved protein, contains Mth938-like domain	127
2918746462	410	99.24	8	403	3	395	2.7e-119	393.4	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
2918746464	440	99.1	1	324	1	331	2.2e-111	367	COG0460	Homoserine dehydrogenase	333
2918746465	471	99.52	1	469	2	418	0.0e+00	463.2	COG0498	Threonine synthase	411
2918746466	181	93.83	1	166	2	153	7.9e-44	144.2	COG1763	Molybdopterin-guanine dinucleotide biosynthesis protein	161
2918746467	425	98.03	7	424	6	404	1.4e-130	430.1	COG0303	Molybdopterin biosynthesis enzyme	404
2918746468	83	100	2	83	1	84	5.8e-21	69.8	COG1977	Molybdopterin converting factor, small subunit	84
2918746469	299	95.65	10	298	4	289	3.3e-73	240.7	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
2918746470	158	96.64	1	150	2	145	6.5e-51	166.8	COG0314	Molybdopterin synthase catalytic subunit	149
2918746471	330	98.12	12	328	5	317	3.1e-63	208.4	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918746472	873	98.76	5	865	1	795	0.0e+00	1125.9	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
2918746474	632	96.74	24	632	16	608	0.0e+00	523.2	COG1022	Long-chain acyl-CoA synthetase (AMP-forming)	613
2918746475	275	99.16	8	252	3	237	1.5e-88	290.6	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2918746476	394	83.33	17	363	5	309	2.4e-35	116.8	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918746477	345	96.59	18	337	10	321	7.2e-76	250.1	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918746478	292	99	2	291	2	299	4.3e-64	211.6	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2918746479	286	98.82	13	267	4	254	4.6e-97	318.9	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2918746480	232	96.17	22	223	5	205	1.9e-28	95	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918746481	394	99.75	3	394	2	394	0.0e+00	458.2	COG0183	Acetyl-CoA acetyltransferase	392
2918746482	135	52.3	3	133	105	229	2.5e-29	96.9	COG1186	Protein chain release factor B	239
2918746483	176	61.07	8	117	15	94	5.5e-06	21.2	COG5395	Uncharacterized membrane protein	131
2918746484	189	85.54	9	188	19	160	7.5e-35	115.1	COG3495	Uncharacterized protein	166
2918746485	581	94.85	16	548	2	535	9.4e-105	345.6	COG0659	Sulfate permease or related transporter, MFS superfamily	554
2918746487	403	99.28	1	403	3	413	3.6e-111	366.5	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
2918746488	80	90.12	1	79	6	78	1.6e-16	55	COG0236	Acyl carrier protein	80
2918746489	238	82.33	7	226	22	212	2.1e-05	18.2	COG0671	Membrane-associated phospholipid phosphatase	232
2918746490	280	89.39	152	279	8	125	1.2e-22	74.5	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918746491	417	49.35	221	416	5	193	1.1e-28	36.6	COG0477	MFS family permease	338
2918746491	417	50.65	13	225	8	201	1.1e-28	64.7	COG0477	MFS family permease	338
2918746492	127	97.44	11	126	3	116	8.9e-36	117.2	COG1393	Arsenate reductase and related proteins, glutaredoxin family	117
2918746493	227	97.21	11	224	2	210	1.7e-34	114.2	COG0625	Glutathione S-transferase	211
2918746494	170	93.42	9	163	10	151	2.1e-44	145.7	COG0054	6,7-dimethyl-8-ribityllumazine synthase (Riboflavin synthase beta chain)	152
2918746496	364	87.78	5	364	27	378	7.1e-65	214.1	COG3214	Uncharacterized conserved protein YcaQ, contains winged helix DNA-binding domain	400
2918746497	292	98.2	11	287	6	278	1.8e-33	110.8	COG1082	Sugar phosphate isomerase/epimerase	274
2918746499	387	98.01	5	384	6	349	7.8e-57	187.9	COG0673	Predicted dehydrogenase	342
2918746500	476	45.84	86	366	102	272	1.2e-07	24.6	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
2918746501	259	96.81	4	256	3	245	3.3e-94	309.6	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2918746502	334	89.55	1	333	9	308	4.0e-46	152.5	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918746503	257	95.35	2	254	12	257	1.2e-77	255.5	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2918746504	327	99.37	1	325	1	317	8.0e-89	292.6	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918746505	218	89.47	8	217	7	193	2.2e-27	91.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918746506	575	97.3	5	570	4	543	0.0e+00	495.2	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
2918746508	260	77.27	102	257	21	122	3.3e-23	76.3	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918746509	75	31.09	1	75	123	196	6.8e-25	83	COG5531	Chromatin remodeling complex protein RSC6, contains SWIB domain	237
2918746511	308	96.68	7	308	6	296	6.3e-34	112.3	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918746512	143	95.83	14	142	4	118	1.0e-23	78.7	COG2105	Uncharacterized conserved protein YtfP, gamma-glutamylcyclotransferase (GGCT)/AIG2-like family	120
2918746513	439	38.98	254	438	289	472	0.0e+00	281.2	COG2224	Isocitrate lyase	433
2918746513	439	54.66	8	262	5	262	0.0e+00	372.6	COG2224	Isocitrate lyase	433
2918746515	635	98.82	34	635	2	588	0.0e+00	866.3	COG0441	Threonyl-tRNA synthetase	589
2918746516	150	72.73	1	129	48	175	4.2e-57	187.2	COG0290	Translation initiation factor IF-3	176
2918746517	67	96.92	1	65	1	63	1.0e-27	91.1	COG0291	Ribosomal protein L35	65
2918746518	119	99.15	1	118	1	117	4.3e-54	176.4	COG0292	Ribosomal protein L20	118
2918746519	358	99.11	1	356	4	337	8.7e-111	365.2	COG0016	Phenylalanyl-tRNA synthetase alpha subunit	335
2918746520	813	99.85	148	812	2	652	0.0e+00	664	COG0072	Phenylalanyl-tRNA synthetase beta subunit	650
2918746521	123	95.74	15	108	2	91	6.0e-31	101.2	COG0776	Bacterial nucleoid DNA-binding protein	94
2918746522	159	71.21	14	156	1	94	2.3e-21	71	COG0789	DNA-binding transcriptional regulator, MerR family	124
2918746524	416	94.63	86	402	9	325	8.8e-26	85.5	COG0582	Integrase	309
2918746526	307	58.31	7	270	14	199	9.0e-17	55.1	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
2918746528	112	87.14	44	112	8	68	2.7e-21	69.5	COG3311	Predicted DNA-binding transcriptional regulator AlpA	70
2918746532	674	94.04	355	665	18	317	3.0e-72	237.8	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918746532	674	98.15	1	357	5	375	1.7e-125	413.4	COG2828	2-Methylaconitate cis-trans-isomerase PrpF (2-methyl citrate pathway)	378
2918746533	323	97.49	4	322	6	316	7.7e-91	299.1	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918746534	317	98.34	5	301	1	296	1.4e-74	246.2	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918746535	444	97.13	2	424	5	410	0.0e+00	460.1	COG1301	Na+/H+-dicarboxylate symporter	415
2918746536	448	98.63	11	446	5	437	0.0e+00	450.9	COG0015	Adenylosuccinate lyase	438
2918746537	276	97.19	11	276	2	278	1.8e-75	248.4	COG2301	Citrate lyase beta subunit	283
2918746538	396	98	1	396	8	400	0.0e+00	444.5	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2918746539	286	98.17	3	285	4	271	9.1e-81	265.8	COG3777	Hydroxyacyl-ACP dehydratase HTD2, hotdog domain	273
2918746540	154	85.81	4	154	21	153	1.9e-19	64.6	COG2606	Cys-tRNA(Pro) deacylase, prolyl-tRNA editing enzyme YbaK/EbsC	155
2918746541	107	96	1	102	1	96	7.0e-25	82	COG4541	Uncharacterized membrane protein	100
2918746542	221	88.28	1	219	27	237	7.7e-47	154.5	COG1296	Predicted branched-chain amino acid permease (azaleucine resistance)	238
2918746543	315	83.33	144	313	15	124	3.8e-25	82.4	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918746544	91	13.06	10	89	232	266	1.3e-05	19.7	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918746547	249	56.18	5	180	30	188	1.4e-12	42	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918746548	395	99.21	2	392	2	376	0.0e+00	519.7	COG2828	2-Methylaconitate cis-trans-isomerase PrpF (2-methyl citrate pathway)	378
2918746549	296	82.66	1	289	59	344	2.4e-60	199.2	COG2706	6-phosphogluconolactonase, cycloisomerase 2 family	346
2918746550	327	97.49	6	325	7	317	9.8e-90	295.4	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918746551	308	31.47	1	81	7	79	4.2e-41	42	COG1802	DNA-binding transcriptional regulator, GntR family	230
2918746551	308	78.02	100	301	38	218	4.2e-41	97.9	COG1802	DNA-binding transcriptional regulator, GntR family	230
2918746552	319	97.49	4	319	7	317	2.0e-87	287.8	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918746553	926	99.08	2	882	7	868	0.0e+00	1085.6	COG1048	Aconitase A	861
2918746555	299	97.67	2	298	4	297	4.4e-71	234.7	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918746558	328	98.34	22	320	2	297	7.2e-47	155.3	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918746559	801	89.28	1	370	15	372	0.0e+00	191.7	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2918746559	801	98.5	372	781	7	401	0.0e+00	340.5	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2918746560	327	96.87	9	327	8	316	6.3e-76	250.1	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918746561	266	97.36	7	263	8	265	6.4e-71	233.4	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918746562	200	92.78	7	198	13	192	3.1e-31	103	COG3707	Two-component response regulator, AmiR/NasT family, consists of REC and RNA-binding antiterminator (ANTAR) domains	194
2918746563	390	94.54	1	355	10	355	1.8e-47	156.7	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918746564	462	98.91	42	449	4	365	2.5e-47	156.3	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918746565	550	97.67	253	550	6	299	7.9e-89	292.5	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2918746566	365	95.36	17	361	13	320	7.2e-75	246.7	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918746567	248	95.7	1	248	9	253	1.5e-105	347	COG4674	ABC-type uncharacterized transport system, ATPase component	249
2918746568	244	94.94	1	242	3	227	6.6e-83	271.6	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2918746569	331	95.85	27	331	8	307	3.2e-63	208.2	COG2421	Acetamidase/formamidase	305
2918746570	253	98.88	3	248	2	266	2.8e-56	185.7	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918746571	492	98.11	47	467	3	418	8.9e-59	186.2	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
2918746572	117	77.08	6	117	19	129	1.5e-13	46	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
2918746573	180	86.96	1	180	1	160	3.1e-51	168.5	COG0431	NAD(P)H-dependent FMN reductase	184
2918746574	104	61.32	4	103	31	95	2.5e-03	12.5	COG2329	Heme-degrading monooxygenase HmoA and related ABM domain proteins	105
2918746575	101	98.91	1	91	1	91	1.6e-19	64.9	COG2350	Uncharacterized conserved protein YciI, contains a putative active-site phosphohistidine	92
2918746576	128	97.06	1	128	4	135	1.0e-31	104.4	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
2918746577	364	99.21	4	351	4	379	5.3e-77	251.4	COG1454	Alcohol dehydrogenase, class IV	377
2918746578	280	94.3	50	279	4	218	1.0e-40	134.1	COG3485	Protocatechuate 3,4-dioxygenase beta subunit	226
2918746579	389	93.16	1	388	14	381	5.0e-33	108.8	COG2814	Predicted arabinose efflux permease, MFS family	394
2918746580	241	80.75	1	237	1	214	1.3e-44	147.3	COG3342	Uncharacterized conserved protein, Ntn-hydrolase superfamily	265
2918746581	327	98.12	9	326	5	317	5.6e-81	266.8	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918746582	239	87.92	1	233	1	233	3.4e-50	165.6	COG3342	Uncharacterized conserved protein, Ntn-hydrolase superfamily	265
2918746583	327	97.81	9	326	6	317	3.2e-81	267.6	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918746584	306	98.34	2	299	3	298	1.3e-69	230	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918746585	211	85.65	8	210	4	182	2.3e-22	75.3	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918746586	555	97.54	1	555	5	558	0.0e+00	452	COG2303	Choline dehydrogenase or related flavoprotein	542
2918746587	410	95.26	2	400	5	386	0.0e+00	433.4	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2918746588	294	99.25	37	291	3	265	6.9e-85	279.3	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918746589	330	99.4	5	328	3	331	4.5e-72	237.9	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2918746591	272	99.19	12	255	1	244	5.1e-48	157.8	COG1414	DNA-binding transcriptional regulator, IclR family	246
2918746593	167	87.22	27	156	16	131	5.4e-21	69.4	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918746594	133	91.91	7	133	8	132	3.2e-26	86.5	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
2918746595	307	86.25	11	287	13	244	6.4e-17	56.2	COG3384	Aromatic ring-opening dioxygenase, catalytic subunit, LigB family	268
2918746596	270	92.57	1	269	9	257	1.4e-16	55.4	COG3384	Aromatic ring-opening dioxygenase, catalytic subunit, LigB family	268
2918746597	491	98.96	4	486	2	475	0.0e+00	519.5	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918746598	150	91.18	8	145	12	135	4.5e-26	85.8	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
2918746599	270	98.11	1	262	4	262	2.1e-95	313.6	COG3971	2-keto-4-pentenoate hydratase	264
2918746600	254	95.83	1	254	7	259	1.9e-76	251.5	COG3971	2-keto-4-pentenoate hydratase	264
2918746601	317	98.39	1	314	1	305	0.0e+00	544.7	COG4569	Acetaldehyde dehydrogenase (acetylating)	310
2918746602	305	74.62	41	292	31	224	1.3e-22	75	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2918746603	354	81.6	4	347	1	337	4.6e-71	234.6	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
2918746604	771	93.46	6	755	53	809	0.0e+00	470.7	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
2918746605	478	88.17	4	458	5	399	5.7e-34	108.4	COG1457	Purine-cytosine permease or related protein	442
2918746606	259	99.09	14	259	2	218	1.1e-56	186.2	COG1878	Kynurenine formamidase	218
2918746607	327	57.55	8	321	17	199	9.5e-21	66.6	COG0657	Acetyl esterase/lipase	312
2918746609	326	92.77	2	326	7	327	3.5e-112	369.6	COG1171	Threonine dehydratase	347
2918746610	331	99.39	1	329	2	329	1.4e-105	347.9	COG2423	Ornithine cyclodeaminase/archaeal alanine dehydrogenase, mu-crystallin family	330
2918746612	96	22.16	1	90	297	382	3.9e-29	96.8	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918746615	682	89.77	26	368	7	243	8.2e-29	94.9	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
2918746617	146	96.26	43	146	2	104	4.7e-37	120.6	COG5489	Uncharacterized conserved protein, DUF736 family	107
2918746619	105	54.62	24	101	2	72	2.5e-13	45.6	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918746622	183	93.75	10	167	10	159	1.4e-20	68.5	COG5419	Uncharacterized protein	160
2918746624	334	84.6	2	319	17	340	1.4e-79	262.8	COG5534	Plasmid replication initiator protein	383
2918746625	253	23.48	41	109	3	64	9.3e-44	68	COG1192	Cellulose biosynthesis protein BcsQ	259
2918746625	253	53.41	104	253	119	259	9.3e-44	75.4	COG1192	Cellulose biosynthesis protein BcsQ	259
2918746628	170	97.69	1	169	4	172	2.2e-55	181.6	COG4959	Type IV secretory pathway, protease TraF	173
2918746629	656	93.66	72	410	7	331	4.6e-70	230.2	COG3843	Type IV secretory pathway, VirD2 components (relaxase)	326
2918746630	456	96.41	11	456	14	443	2.1e-126	416.8	COG0160	4-aminobutyrate aminotransferase or related aminotransferase	447
2918746632	140	20.64	19	136	14	110	1.6e-08	28	COG2865	Predicted transcriptional regulator, contains HTH domain	467
2918746633	243	92.67	1	233	9	223	9.0e-42	137.6	COG1802	DNA-binding transcriptional regulator, GntR family	230
2918746634	270	98.76	12	269	3	241	1.6e-98	323.4	COG1126	ABC-type polar amino acid transport system, ATPase component	240
2918746635	259	99.25	3	257	2	267	3.6e-71	234.5	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918746636	313	93.64	23	296	10	274	1.2e-24	81.5	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918746637	530	10.07	447	524	356	412	6.2e-28	2.7	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
2918746637	530	47.53	1	339	6	274	6.2e-28	90.8	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
2918746638	222	92.98	3	222	14	225	3.2e-53	175.3	COG0765	ABC-type amino acid transport system, permease component	222
2918746639	226	93.86	3	226	12	225	3.5e-57	188.3	COG0765	ABC-type amino acid transport system, permease component	222
2918746640	351	98.89	1	351	5	360	8.6e-46	151.2	COG3203	Outer membrane protein (porin)	354
2918746641	396	100	1	393	1	396	0.0e+00	521.9	COG1448	Aspartate/tyrosine/aromatic aminotransferase	396
2918746642	240	94.76	4	230	10	226	3.8e-46	151.8	COG3382	B3/B4 domain (DNA/RNA-binding domain of Phe-tRNA-synthetase)	229
2918746643	480	98.96	2	480	2	475	0.0e+00	519	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918746644	284	78.64	3	279	58	300	5.4e-55	181.2	COG1893	Ketopantoate reductase	307
2918746645	317	81.68	20	270	49	271	3.2e-47	156	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
2918746646	302	91.45	1	279	22	267	1.5e-20	68.3	COG3384	Aromatic ring-opening dioxygenase, catalytic subunit, LigB family	268
2918746647	491	99.16	15	483	2	476	0.0e+00	506.7	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918746648	479	97.23	7	474	13	468	2.1e-111	367.7	COG0277	FAD/FMN-containing dehydrogenase	459
2918746649	268	98.43	2	256	4	254	7.2e-111	364.1	COG3836	2-keto-3-deoxy-L-rhamnonate aldolase RhmA	255
2918746650	268	97.73	2	268	5	262	2.5e-102	336.2	COG3971	2-keto-4-pentenoate hydratase	264
2918746651	306	98.34	6	303	2	297	5.8e-55	181.9	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918746652	146	75.96	41	140	21	99	1.7e-10	34.2	COG2944	DNA-binding transcriptional regulator YiaG, XRE-type HTH domain	104
2918746656	321	65.15	146	320	40	125	8.8e-17	55.3	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918746659	275	97.35	7	272	8	264	3.4e-35	116.3	COG5266	Uncharacterized conserved protein, contains GH25 family domain	264
2918746661	329	16.21	2	67	7	59	1.7e-08	4.3	COG4531	ABC-type Zn2+ transport system, periplasmic component/surface adhesin	318
2918746661	329	41.9	146	314	162	298	1.7e-08	22.4	COG4531	ABC-type Zn2+ transport system, periplasmic component/surface adhesin	318
2918746662	301	96.74	17	296	5	271	2.6e-70	231.3	COG1108	ABC-type Mn2+/Zn2+ transport system, permease component	274
2918746663	225	88.19	2	225	4	227	7.7e-62	203.7	COG1121	ABC-type Mn2+/Zn2+ transport system, ATPase component	254
2918746664	310	95.74	5	307	12	303	2.0e-62	205.8	COG0803	ABC-type Zn uptake system ZnuABC, Zn-binding component ZnuA	303
2918746666	163	11.85	1	155	403	503	1.7e-02	8	COG3264	Small-conductance mechanosensitive channel	835
2918746671	706	95.09	3	706	40	795	4.4e-71	235.3	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2918746672	223	97.79	3	206	2	178	6.1e-38	124.2	COG3038	Cytochrome b561	181
2918746673	484	98.75	5	483	2	474	0.0e+00	537.8	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918746674	215	92.56	1	206	13	211	5.1e-35	116	COG0625	Glutathione S-transferase	211
2918746675	326	94.67	1	323	8	309	2.6e-77	254.7	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918746676	328	97.18	7	327	9	318	2.3e-89	294.3	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918746677	276	99.19	36	276	1	244	2.1e-48	158.9	COG1414	DNA-binding transcriptional regulator, IclR family	246
2918746678	208	99.07	1	206	1	213	3.0e-43	142.8	COG0625	Glutathione S-transferase	211
2918746679	351	51.6	166	351	105	217	2.8e-04	13.3	COG1878	Kynurenine formamidase	218
2918746680	332	97.49	9	329	5	315	1.9e-69	228.8	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918746681	244	98.78	2	244	2	244	7.9e-42	137.6	COG1414	DNA-binding transcriptional regulator, IclR family	246
2918746682	279	85.89	1	278	44	317	1.2e-62	206.5	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918746683	519	95.86	3	519	1	532	6.9e-91	297.2	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
2918746684	264	99.25	3	261	2	267	1.2e-59	196.7	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918746685	351	6.19	90	126	100	120	4.4e-13	6.8	COG4447	Uncharacterized protein related to plant photosystem II stability/assembly factor	339
2918746685	351	22.42	1	101	101	176	4.4e-13	12.5	COG4447	Uncharacterized protein related to plant photosystem II stability/assembly factor	339
2918746685	351	42.18	138	315	105	247	4.4e-13	23.4	COG4447	Uncharacterized protein related to plant photosystem II stability/assembly factor	339
2918746686	159	16.85	3	64	170	215	3.8e-14	28.6	COG2514	Catechol-2,3-dioxygenase	265
2918746686	159	17.22	73	150	82	128	3.8e-14	17.2	COG2514	Catechol-2,3-dioxygenase	265
2918746688	289	98.31	4	280	4	293	8.7e-49	161.4	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918746690	560	97.2	5	386	4	385	3.5e-70	231.8	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2918746691	477	98.54	7	477	3	474	0.0e+00	535	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918746692	491	98.33	12	481	2	472	0.0e+00	600.9	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918746693	198	84.26	9	193	9	190	3.6e-15	48.7	COG0778	Nitroreductase	207
2918746694	490	86.79	17	482	19	445	6.2e-44	144.9	COG0531	Amino acid transporter	466
2918746695	311	96.01	18	310	2	290	2.3e-49	163.4	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918746696	666	94.68	1	592	6	575	0.0e+00	642.7	COG3505	Type IV secretory pathway, VirD4 component, TraG/TraD family ATPase	596
2918746697	155	18.07	48	104	12	26	1.2e-04	2.3	COG3905	Predicted transcriptional regulator	83
2918746697	155	42.17	3	55	7	41	1.2e-04	13.6	COG3905	Predicted transcriptional regulator	83
2918746698	321	83.15	1	298	50	350	1.1e-100	331.6	COG4962	Pilus assembly protein, ATPase of CpaF family	355
2918746699	110	98.15	1	109	2	107	1.4e-32	106.9	COG3838	Type IV secretory pathway, VirB2 components (pilins)	108
2918746700	94	91.4	5	94	8	92	9.5e-37	119.9	COG5268	Type IV secretory pathway, TrbD component	93
2918746701	832	99.62	1	816	3	799	0.0e+00	725.5	COG3451	Type IV secretory pathway, VirB4 component	796
2918746702	254	90.08	4	254	24	250	1.6e-74	245.2	COG5314	Conjugal transfer/entry exclusion protein	252
2918746704	457	94.27	1	450	27	454	5.2e-122	402.5	COG3846	Type IV secretory pathway, TrbL components	452
2918746705	238	99.56	1	228	1	227	5.7e-107	350.9	COG3701	Type IV secretory pathway, TrbF components	228
2918746706	334	94.87	44	330	2	260	2.7e-75	247.8	COG3504	Type IV secretory pathway, VirB9 components	265
2918746707	439	97.71	15	433	7	390	1.0e-95	315.9	COG2948	Type IV secretory pathway, VirB10 components	360
2918746708	77	96.1	3	77	1	74	5.2e-33	107.8	COG5639	Uncharacterized protein	77
2918746711	287	6.4	258	285	231	246	5.6e-53	3.8	COG4422	Bacteriophage protein gp37	250
2918746711	287	90.8	1	250	3	229	5.6e-53	169.1	COG4422	Bacteriophage protein gp37	250
2918746714	591	60.74	139	235	50	131	3.3e-03	11	COG4954	Uncharacterized protein	135
2918746717	457	87.84	384	454	5	69	1.1e-06	22.5	COG4479	Uncharacterized protein YozE, UPF0346 family	74
2918746722	154	32.31	1	99	30	71	4.0e-08	28.9	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918746723	68	16.61	13	66	2	51	1.7e-18	62	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918746725	172	87.93	4	172	22	174	6.4e-29	95.7	COG5430	Spore coat protein U (SCPU) domain, function unknown	174
2918746726	746	90.21	2	731	64	819	5.5e-112	369.7	COG3188	Outer membrane usher protein FimD/PapC	835
2918746727	265	92.05	2	249	9	228	3.0e-32	106.2	COG3121	P pilus assembly protein, chaperone PapD	235
2918746728	176	87.93	4	176	22	174	1.9e-32	107.2	COG5430	Spore coat protein U (SCPU) domain, function unknown	174
2918746729	374	80.96	12	374	71	389	1.2e-33	111.9	COG0642	Signal transduction histidine kinase	336
2918746731	528	65.99	88	518	130	389	9.1e-31	102.4	COG0642	Signal transduction histidine kinase	336
2918746732	250	68.11	1	221	2	206	4.2e-51	169	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918746733	217	98.54	11	206	2	204	2.0e-23	70.5	COG1335	Nicotinamidase-related amidase	205
2918746734	422	39.07	28	349	72	180	1.1e-04	17.2	COG0500	SAM-dependent methyltransferase	257
2918746736	335	70.69	23	167	44	166	4.9e-39	24.2	COG5430	Spore coat protein U (SCPU) domain, function unknown	174
2918746736	335	98.28	158	335	4	174	4.9e-39	111.1	COG5430	Spore coat protein U (SCPU) domain, function unknown	174
2918746737	775	88.9	11	769	93	837	7.5e-122	402.5	COG3188	Outer membrane usher protein FimD/PapC	835
2918746738	242	87.45	1	226	8	216	3.9e-40	132.1	COG3121	P pilus assembly protein, chaperone PapD	235
2918746739	168	89.66	2	168	19	174	1.0e-30	101.5	COG5430	Spore coat protein U (SCPU) domain, function unknown	174
2918746740	357	23.69	229	296	123	181	4.7e-44	15.5	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
2918746740	357	92.37	13	273	17	246	4.7e-44	140.4	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
2918746741	235	88	3	235	28	225	2.8e-74	243.7	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
2918746742	377	98.75	1	358	2	318	3.3e-76	251.3	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2918746745	421	81.54	3	419	15	407	4.7e-05	14.8	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
2918746747	281	96.77	1	280	8	277	5.7e-125	410.6	COG2877	3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase	279
2918746748	316	98.02	11	211	3	200	9.7e-75	244.8	COG0794	D-arabinose 5-phosphate isomerase GutQ	202
2918746749	186	85.26	6	183	23	184	1.7e-28	94.1	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
2918746750	752	24.52	21	152	12	125	1.2e-60	62	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
2918746750	752	58.28	210	489	194	464	1.2e-60	139.5	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
2918746750	752	78.67	499	752	30	254	1.5e-46	152.8	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
2918746751	144	98.65	1	141	2	147	3.7e-42	138.6	COG0394	Protein-tyrosine-phosphatase	139
2918746755	264	73.67	1	220	1	291	1.4e-40	134.3	COG1409	3',5'-cyclic AMP phosphodiesterase CpdA	301
2918746756	450	98.55	7	442	3	411	7.0e-65	213.9	COG3395	Uncharacterized conserved protein YgbK, DUF1537 family	413
2918746757	422	91.38	3	422	34	425	1.6e-107	354.2	COG1850	Ribulose 1,5-bisphosphate carboxylase, large subunit, or a RuBisCO-like protein	429
2918746758	179	77.4	7	145	5	117	4.3e-04	15.6	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2918746759	631	86.44	25	190	10	162	3.4e-39	128.8	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
2918746759	631	98.42	255	631	3	375	1.8e-100	331.3	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
2918746760	339	96.99	5	337	7	328	3.0e-91	300.6	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
2918746761	349	62.08	15	349	80	282	7.1e-47	154	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
2918746762	267	97.65	1	254	5	253	3.1e-111	365.3	COG3836	2-keto-3-deoxy-L-rhamnonate aldolase RhmA	255
2918746763	489	98.75	13	488	2	474	0.0e+00	595.4	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918746764	507	15.33	9	96	171	231	0.0e+00	11.9	COG2721	Altronate dehydratase	381
2918746764	507	99.5	103	507	2	397	0.0e+00	519.1	COG2721	Altronate dehydratase	381
2918746765	331	98.12	10	326	5	317	5.1e-82	270.1	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918746766	313	98.67	12	313	2	298	1.4e-53	177.2	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918746767	139	57.8	4	138	13	138	3.8e-12	40.6	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2918746771	64	48.87	1	64	61	125	5.8e-16	53.3	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918746772	445	78.49	10	233	14	148	4.6e-12	39.7	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2918746774	240	97.83	34	226	2	181	2.7e-48	158.7	COG0431	NAD(P)H-dependent FMN reductase	184
2918746775	148	97.44	6	122	2	115	3.6e-37	121.6	COG1393	Arsenate reductase and related proteins, glutaredoxin family	117
2918746776	107	71.19	1	96	16	99	2.5e-08	29	COG0640	DNA-binding transcriptional regulator, ArsR family	110
2918746777	161	23.97	1	127	1	35	4.2e-04	15.6	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2918746778	164	97.97	1	142	2	146	1.0e-27	91.6	COG0394	Protein-tyrosine-phosphatase	139
2918746779	360	96.5	15	359	9	339	1.7e-111	367	COG0798	Arsenite efflux pump ArsB, ACR3 family	342
2918746780	260	99.61	1	257	1	258	2.5e-80	264.1	COG0708	Exonuclease III	261
2918746781	248	87.55	14	247	16	240	1.7e-51	168.4	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
2918746782	642	98.03	81	642	8	505	0.0e+00	507.1	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
2918746783	1026	20.25	467	523	101	149	6.0e-44	20.2	COG2202	PAS domain	232
2918746783	1026	63.64	688	854	89	242	6.0e-44	56.9	COG2202	PAS domain	232
2918746783	1026	65.29	522	718	47	204	6.0e-44	30.6	COG2202	PAS domain	232
2918746783	1026	72.31	254	482	68	242	6.0e-44	49.7	COG2202	PAS domain	232
2918746783	1026	95.63	842	1025	6	180	3.3e-51	167.5	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2918746784	554	97.49	10	514	1	504	3.8e-97	321.2	COG0366	Glycosidase	505
2918746785	536	97.29	10	517	2	504	0.0e+00	459	COG0366	Glycosidase	505
2918746786	448	96.06	2	430	16	405	1.8e-112	370.8	COG2312	Erythromycin esterase homolog	405
2918746787	221	95.91	3	219	3	213	1.4e-83	274.1	COG1926	Predicted phosphoribosyltransferase	220
2918746790	139	86.3	1	137	21	146	2.6e-25	83.6	COG0071	Molecular chaperone IbpA, HSP20 family	146
2918746791	145	89.04	1	145	16	145	2.0e-28	93.7	COG0071	Molecular chaperone IbpA, HSP20 family	146
2918746794	632	98.89	6	629	7	632	0.0e+00	816.5	COG0296	1,4-alpha-glucan branching enzyme	628
2918746795	682	14.7	519	630	430	505	8.1e-31	11.8	COG0366	Glycosidase	505
2918746795	682	60.35	217	495	2	313	8.1e-31	88.8	COG0366	Glycosidase	505
2918746796	1109	87.8	668	1107	49	451	7.5e-89	292.8	COG3281	Predicted trehalose synthase	438
2918746796	1109	99.81	27	530	1	516	3.2e-122	403.5	COG0366	Glycosidase	505
2918746798	721	95.17	3	718	7	676	0.0e+00	916.6	COG1523	Pullulanase/glycogen debranching enzyme	697
2918746799	613	88.94	2	589	22	584	0.0e+00	526.5	COG0296	1,4-alpha-glucan branching enzyme	628
2918746800	1690	6.43	1318	1355	378	411	0.0e+00	.8	COG1640	4-alpha-glucanotransferase	520
2918746800	1690	99.43	150	718	1	526	0.0e+00	560.5	COG1640	4-alpha-glucanotransferase	520
2918746800	1690	99.44	730	1685	2	885	0.0e+00	976	COG3280	Maltooligosyltrehalose synthase	889
2918746802	112	68.18	4	68	8	67	1.9e-05	18.9	COG1873	Sporulation protein YlmC, PRC-barrel domain family	87
2918746803	136	89.39	1	108	6	123	1.1e-19	65.4	COG0789	DNA-binding transcriptional regulator, MerR family	124
2918746804	283	58.78	4	273	36	199	1.7e-16	55.5	COG0500	SAM-dependent methyltransferase	257
2918746805	844	78.87	645	827	29	196	9.1e-15	49.3	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
2918746805	844	92.27	25	573	8	532	0.0e+00	588.8	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
2918746806	314	88.98	2	236	18	243	2.2e-49	162	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
2918746807	132	75	18	132	29	130	5.0e-10	26	COG3474	Cytochrome c2	135
2918746808	287	53.05	19	174	57	143	5.2e-18	36.2	COG2010	Cytochrome c, mono- and diheme variants	150
2918746808	287	55.49	156	286	50	140	5.2e-18	27	COG2010	Cytochrome c, mono- and diheme variants	150
2918746812	593	99.1	2	568	2	551	0.0e+00	481	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
2918746813	159	66.07	10	159	3	150	1.1e-37	124	COG2323	Uncharacterized membrane protein YcaP, DUF421 family	224
2918746814	104	57.58	1	95	4	60	3.0e-05	18.7	COG3668	Plasmid stabilization system protein ParE	98
2918746815	130	97.95	1	128	3	145	9.5e-08	27.3	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2918746816	202	87.38	18	191	5	184	1.4e-24	81.4	COG1335	Nicotinamidase-related amidase	205
2918746819	259	20	146	238	218	276	1.3e-15	9.8	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918746819	259	49.83	7	171	21	167	1.3e-15	44.5	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918746821	164	46.78	4	130	69	148	1.5e-05	19	COG5592	Hemerythrin superfamily protein	171
2918746822	188	13.57	80	133	115	144	3.6e-06	7.3	COG2846	Iron-sulfur cluster repair protein YtfE, RIC family, contains ScdAN and hemerythrin domains	221
2918746822	188	33.03	4	112	102	174	3.6e-06	14.1	COG2846	Iron-sulfur cluster repair protein YtfE, RIC family, contains ScdAN and hemerythrin domains	221
2918746824	807	61.22	644	797	3	122	5.5e-08	26.7	COG0693	Putative intracellular protease/amidase	188
2918746824	807	96.41	112	615	11	493	0.0e+00	700	COG0753	Catalase	496
2918746825	437	97.94	34	419	4	383	3.6e-76	251.4	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918746826	474	99.58	1	474	2	480	0.0e+00	588.3	COG5310	Homospermidine synthase	481
2918746827	537	75.26	32	484	67	431	7.0e-84	276.6	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
2918746828	167	41.77	8	166	173	304	5.5e-37	122.8	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
2918746829	168	86.67	13	167	13	155	5.1e-59	192.8	COG3045	Periplasmic catabolite regulation protein CreA (function unknown)	165
2918746830	183	93.84	36	173	4	140	2.3e-24	80.4	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
2918746831	233	78.39	4	233	56	269	6.2e-72	236.9	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
2918746832	213	97.67	2	212	1	210	1.8e-49	163	COG0625	Glutathione S-transferase	211
2918746833	255	98.41	4	255	2	248	7.3e-74	242.8	COG1496	Copper oxidase (laccase) domain	249
2918746834	107	46.1	1	85	19	83	2.2e-03	12.7	COG1585	Membrane protein implicated in regulation of membrane protease activity	140
2918746835	584	99.78	127	582	1	451	0.0e+00	556	COG3243	Poly(3-hydroxyalkanoate) synthetase	445
2918746836	392	99.75	1	392	1	393	0.0e+00	486.1	COG0183	Acetyl-CoA acetyltransferase	392
2918746837	303	98.67	3	301	1	297	9.4e-59	194.2	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918746838	324	97.18	1	322	7	316	8.9e-90	295.5	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918746839	302	97.44	17	301	6	271	2.5e-79	260.9	COG3777	Hydroxyacyl-ACP dehydratase HTD2, hotdog domain	273
2918746840	393	98.5	1	393	7	401	0.0e+00	440.2	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2918746841	294	97.54	10	286	2	279	5.6e-74	243.3	COG2301	Citrate lyase beta subunit	283
2918746842	334	98.43	7	333	5	318	1.9e-99	327.4	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918746843	82	17.17	6	78	158	197	4.8e-05	17.7	COG2849	Antitoxin component YwqK of the YwqJK toxin-antitoxin module	230
2918746844	172	93.87	7	166	9	161	7.7e-36	117.4	COG1546	Nicotinamide mononucleotide (NMN) deamidase PncC	162
2918746845	245	98.51	1	243	3	266	1.3e-70	232.6	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918746846	447	97.37	10	434	4	410	0.0e+00	527.9	COG1301	Na+/H+-dicarboxylate symporter	415
2918746847	567	96.81	1	411	1	395	0.0e+00	544.1	COG4651	Predicted Kef-type K+ transport protein, K+/H+ antiporter domain	408
2918746849	452	98.2	20	342	3	330	2.2e-105	347.2	COG0460	Homoserine dehydrogenase	333
2918746850	113	29.11	73	107	38	60	1.0e-03	9.5	COG4238	Outer membrane murein-binding lipoprotein Lpp	78
2918746850	113	30.38	53	83	43	66	1.0e-03	3	COG4238	Outer membrane murein-binding lipoprotein Lpp	78
2918746850	113	31.65	18	56	31	55	1.0e-03	5.2	COG4238	Outer membrane murein-binding lipoprotein Lpp	78
2918746851	283	87.23	1	279	29	267	3.6e-60	198	COG1718	Serine/threonine-protein kinase RIO1	268
2918746853	323	99.06	1	321	2	317	1.7e-78	258.6	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918746856	323	98.12	1	322	6	318	1.5e-88	291.6	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918746858	265	98.95	1	221	1	189	2.8e-66	217.5	COG2249	Putative NADPH-quinone reductase (modulator of drug activity B)	189
2918746859	297	97.67	7	297	1	294	7.7e-49	161.6	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918746860	264	70.14	1	163	50	197	2.3e-19	64.2	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918746862	584	97.76	1	577	8	574	0.0e+00	653.7	COG4618	ABC-type protease/lipase transport system, ATPase and permease components	580
2918746863	575	96.03	1	574	12	568	0.0e+00	677.2	COG4618	ABC-type protease/lipase transport system, ATPase and permease components	580
2918746864	457	97.44	26	448	10	389	6.1e-34	112.3	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918746865	445	88.48	4	440	44	450	3.1e-70	231.7	COG1538	Outer membrane protein TolC	457
2918746866	145	89.24	1	144	12	152	2.3e-41	136.1	COG1522	DNA-binding transcriptional regulator, Lrp family	154
2918746867	599	98.92	28	591	2	550	0.0e+00	686.7	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
2918746868	335	98.31	62	335	4	293	2.8e-51	169.3	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918746869	158	94.74	31	156	6	131	6.0e-26	85.5	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918746872	320	95.36	7	320	13	341	1.8e-77	255.5	COG2070	NAD(P)H-dependent flavin oxidoreductase YrpB, nitropropane dioxygenase family	336
2918746873	387	95.12	9	386	9	378	4.9e-25	82.4	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
2918746874	568	93.56	18	565	7	529	0.0e+00	508.9	COG4988	ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components	559
2918746875	568	96.34	8	562	5	556	0.0e+00	500.3	COG4987	ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components	573
2918746876	538	97.81	2	521	2	447	0.0e+00	629.5	COG1271	Cytochrome bd-type quinol oxidase, subunit 1	457
2918746877	384	99.13	6	379	2	343	2.6e-122	403.1	COG1294	Cytochrome bd-type quinol oxidase, subunit 2	346
2918746878	49	94.59	1	38	1	35	2.8e-22	73.1	COG4890	Predicted outer membrane lipoprotein	37
2918746879	193	97.74	3	181	4	176	1.2e-57	189.3	COG1510	DNA-binding transcriptional regulator GbsR, MarR family	177
2918746880	140	58.78	31	130	49	125	1.0e-11	39.1	COG1917	Cupin domain protein related to quercetin dioxygenase	131
2918746881	148	92.37	1	102	8	116	6.6e-18	59.8	COG0640	DNA-binding transcriptional regulator, ArsR family	110
2918746882	107	70.7	1	103	46	156	2.0e-21	71.2	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
2918746883	61	47.41	1	61	18	72	3.3e-03	12.1	COG5336	FoF1-type ATP synthase assembly protein I	116
2918746884	370	98.38	2	362	2	365	0.0e+00	498	COG0082	Chorismate synthase	369
2918746885	394	47.78	205	393	8	190	1.3e-17	29.2	COG0477	MFS family permease	338
2918746885	394	72.58	9	274	8	285	1.3e-17	34.2	COG0477	MFS family permease	338
2918746889	334	93.88	1	325	8	314	4.2e-70	230.7	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
2918746890	319	95.3	7	319	11	314	5.4e-92	302.6	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
2918746891	265	49.9	3	265	5	254	1.8e-87	288.6	COG1129	ABC-type sugar transport system, ATPase component	500
2918746892	409	97.74	90	400	1	303	9.8e-35	114.6	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
2918746894	340	98.43	6	337	5	318	8.4e-71	233.2	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918746895	472	87.56	95	472	45	389	8.6e-53	175.1	COG0642	Signal transduction histidine kinase	336
2918746896	221	99.14	1	221	1	230	6.4e-68	223.1	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918746897	335	96.87	16	333	9	317	2.4e-82	271	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918746898	264	97.56	22	264	2	241	5.7e-61	200.1	COG1414	DNA-binding transcriptional regulator, IclR family	246
2918746899	307	95.07	4	284	4	273	1.2e-48	160	COG0169	Shikimate 5-dehydrogenase	283
2918746900	201	94.35	1	175	5	171	4.1e-47	154.5	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
2918746901	426	99.21	47	425	2	377	0.0e+00	464.3	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
2918746902	334	97.29	1	331	6	328	1.1e-109	361.2	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
2918746903	277	90.49	1	274	1	257	4.1e-58	191.2	COG0169	Shikimate 5-dehydrogenase	283
2918746904	402	79.73	4	368	6	355	5.9e-101	332.8	COG0015	Adenylosuccinate lyase	438
2918746905	143	95.97	15	136	2	120	1.6e-21	71.2	COG0599	Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family	124
2918746906	406	47.52	203	404	14	195	7.6e-27	10.4	COG0477	MFS family permease	338
2918746906	406	69.19	7	246	8	272	7.6e-27	80.7	COG0477	MFS family permease	338
2918746907	254	91.19	2	254	25	293	1.2e-36	121.5	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918746908	632	95.04	277	632	9	353	6.6e-97	319.1	COG3185	4-hydroxyphenylpyruvate dioxygenase and related hemolysins	363
2918746908	632	96.4	1	270	3	270	8.2e-47	153.8	COG1082	Sugar phosphate isomerase/epimerase	274
2918746909	470	44.91	241	436	24	195	8.9e-38	24.6	COG0477	MFS family permease	338
2918746909	470	70.76	16	278	3	273	8.9e-38	102.8	COG0477	MFS family permease	338
2918746910	224	94.67	1	223	5	217	8.3e-63	206.7	COG2761	Predicted dithiol-disulfide isomerase, DsbA family	225
2918746912	531	70.16	83	531	97	444	6.0e-89	292.9	COG5267	Uncharacterized conserved protein, DUF1800 family	496
2918746913	403	94.5	1	398	7	401	6.8e-62	204.2	COG4102	Uncharacterized conserved protein, DUF1501 family	418
2918746914	248	94.37	1	240	3	220	2.1e-82	270.6	COG3148	Uncharacterized conserved protein YfiP, DTW domain	231
2918746915	352	97.68	1	352	3	339	3.3e-82	271.2	COG2070	NAD(P)H-dependent flavin oxidoreductase YrpB, nitropropane dioxygenase family	336
2918746916	221	89.95	5	220	19	206	1.6e-36	120.3	COG0400	Predicted esterase	207
2918746919	968	30.99	107	391	201	354	0.0e+00	25.5	COG1003	Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain	496
2918746919	968	94.37	458	935	26	494	0.0e+00	692.8	COG1003	Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain	496
2918746920	123	92.37	1	123	9	129	6.2e-46	150	COG0509	Glycine cleavage system H protein (lipoate-binding)	131
2918746921	392	98.96	9	392	2	382	1.9e-104	343.7	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
2918746924	182	13.26	115	174	24	47	6.9e-01	2.3	COG3149	Type II secretory pathway, component PulM	181
2918746924	182	34.25	4	111	56	117	6.9e-01	4.8	COG3149	Type II secretory pathway, component PulM	181
2918746925	425	99.21	45	423	1	376	0.0e+00	456	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
2918746926	164	77.97	2	163	15	152	5.2e-31	101.8	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
2918746927	323	98.49	1	323	2	328	1.4e-111	367.6	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
2918746928	338	97.2	1	330	2	313	2.3e-44	146.7	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2918746929	301	93.69	1	291	1	282	2.0e-53	176.6	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918746930	271	95.47	3	267	12	264	1.1e-116	383	COG4336	Uncharacterized protein YcsI, UPF0317 family	265
2918746931	430	50.39	238	428	11	203	8.0e-41	35.6	COG0477	MFS family permease	338
2918746931	430	83.55	29	288	2	321	8.0e-41	103.9	COG0477	MFS family permease	338
2918746932	1218	92.57	707	1218	2	524	0.0e+00	670	COG0146	N-methylhydantoinase B/oxoprolinase/acetone carboxylase, alpha subunit	563
2918746932	1218	98.82	9	695	2	672	0.0e+00	733.8	COG0145	N-methylhydantoinase A/oxoprolinase/acetone carboxylase, beta subunit	674
2918746933	567	57.53	493	559	20	61	1.7e-03	12.3	COG1146	NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit	68
2918746933	567	100	15	478	1	407	2.0e-125	413.5	COG0644	Dehydrogenase (flavoprotein)	396
2918746934	260	99.25	5	259	2	267	6.5e-72	236.9	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918746935	140	94.24	8	140	3	133	5.4e-27	89.1	COG0824	Acyl-CoA thioesterase FadM	137
2918746936	450	81.22	42	449	59	378	2.7e-42	140.3	COG0642	Signal transduction histidine kinase	336
2918746937	213	93.97	1	209	13	230	8.0e-65	213	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918746938	241	81.12	10	233	32	233	2.1e-43	143.2	COG3907	Membrane-associated enzyme, PAP2 (acid phosphatase) superfamily	249
2918746939	189	64.66	2	186	58	207	6.8e-17	56.8	COG0671	Membrane-associated phospholipid phosphatase	232
2918746940	583	96.58	36	583	11	547	0.0e+00	464.7	COG2194	Phosphoethanolamine transferase for periplasmic glucans (OPG), alkaline phosphatase superfamily	555
2918746941	193	91.94	2	180	15	185	4.5e-34	112.8	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
2918746942	419	48.11	178	356	75	176	7.2e-08	25.7	COG0560	Phosphoserine phosphatase	212
2918746943	260	79.93	1	243	59	293	1.8e-77	255	COG4302	Ethanolamine ammonia-lyase, small subunit	294
2918746944	464	97.79	1	451	1	443	0.0e+00	701.8	COG4303	Ethanolamine ammonia-lyase, large subunit	453
2918746945	473	92.89	15	469	9	465	3.0e-63	208.5	COG0531	Amino acid transporter	466
2918746946	122	53.4	3	120	97	206	1.6e-53	176.3	COG0545	FKBP-type peptidyl-prolyl cis-trans isomerase	205
2918746947	250	99.25	3	249	2	267	2.8e-72	238	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918746948	305	97.67	2	301	3	296	1.6e-69	229.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918746949	532	96.82	1	532	12	529	0.0e+00	649.3	COG3131	Periplasmic glucans biosynthesis protein	534
2918746950	285	88.33	1	270	10	274	2.5e-31	103.5	COG3315	O-Methyltransferase involved in polyketide biosynthesis	297
2918746952	502	99.37	5	489	2	477	0.0e+00	527.3	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918746953	314	98.01	9	312	3	297	1.1e-62	207	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918746954	303	96.68	10	302	2	292	3.6e-53	175.8	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918746955	391	93.02	1	387	9	381	0.0e+00	437.8	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2918746956	327	69.98	7	305	2	290	5.6e-59	194.6	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
2918746957	323	97.81	1	321	6	317	3.6e-96	316.5	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918746959	188	76.25	118	187	15	75	3.6e-17	55.9	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2918746960	267	98.64	1	221	2	218	2.8e-96	315.4	COG1788	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit	220
2918746961	212	92	1	212	6	212	2.3e-92	303.1	COG2057	Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit	225
2918746962	461	35.66	24	195	189	331	1.1e-46	9.5	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2918746962	461	50.37	196	397	7	208	1.1e-46	149.1	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2918746964	298	99	1	292	1	298	2.3e-58	192.9	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918746965	507	99.16	14	492	2	476	0.0e+00	488.5	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918746966	118	84.38	1	116	15	122	1.8e-28	93.6	COG3755	Uncharacterized conserved protein YecT, DUF1311 family	127
2918746967	384	99	1	382	1	395	0.0e+00	441.3	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918746968	371	96.23	2	340	11	265	3.7e-64	210.4	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918746969	300	99.65	1	296	1	285	6.1e-98	322.1	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
2918746971	431	48.83	10	219	8	194	5.2e-30	63.5	COG0477	MFS family permease	338
2918746971	431	50.39	227	423	2	194	5.2e-30	42.3	COG0477	MFS family permease	338
2918746972	327	98.01	6	297	2	296	4.6e-66	218.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918746973	146	51.52	15	84	29	79	1.5e-02	11.9	COG2440	Ferredoxin-like protein FixX	99
2918746974	308	97.34	6	303	2	294	9.5e-57	187.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918746975	781	55.29	5	358	17	199	0.0e+00	40.8	COG0620	Methionine synthase II (cobalamin-independent)	330
2918746975	781	99.7	440	777	2	331	0.0e+00	430.3	COG0620	Methionine synthase II (cobalamin-independent)	330
2918746977	503	59.23	5	130	2	78	1.9e-16	53.1	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918746977	503	99.1	143	474	2	330	0.0e+00	460.8	COG3800	Predicted transcriptional regulator	332
2918746978	178	81.53	37	178	7	134	1.0e-34	113.9	COG1607	Acyl-CoA hydrolase	157
2918746979	388	95.96	9	387	17	396	0.0e+00	449.1	COG0372	Citrate synthase	390
2918746980	484	99.56	7	482	2	455	0.0e+00	596.6	COG2079	2-methylcitrate dehydratase PrpD	453
2918746981	292	97.94	1	291	4	288	1.5e-84	278.1	COG2513	2-Methylisocitrate lyase and related enzymes, PEP mutase family	289
2918746983	191	97.34	6	189	3	185	1.1e-75	247.9	COG2818	3-methyladenine DNA glycosylase Tag	188
2918746984	158	85.62	7	154	13	137	1.1e-17	59	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
2918746988	696	15.81	577	695	41	111	5.4e+00	1.3	COG1322	DNA anti-recombination protein (rearrangement mutator) RmuC	448
2918746988	696	16.48	298	396	93	166	5.4e+00	6.3	COG1322	DNA anti-recombination protein (rearrangement mutator) RmuC	448
2918746988	696	29.84	166	318	38	171	5.4e+00	3.4	COG1322	DNA anti-recombination protein (rearrangement mutator) RmuC	448
2918746988	696	33.41	392	581	34	183	5.4e+00	1.2	COG1322	DNA anti-recombination protein (rearrangement mutator) RmuC	448
2918746989	218	52.59	38	209	126	267	1.4e-32	108	COG1360	Flagellar motor protein MotB	244
2918746992	320	37.66	163	318	217	361	4.2e-71	98.6	COG0484	DnaJ-class molecular chaperone with C-terminal Zn finger domain	371
2918746992	320	38.18	1	165	3	149	4.2e-71	132.3	COG0484	DnaJ-class molecular chaperone with C-terminal Zn finger domain	371
2918746993	213	77.03	31	188	5	165	5.1e-31	100.1	COG0406	Broad specificity phosphatase PhoE	208
2918746994	192	93.49	2	191	1	201	6.4e-41	135.1	COG0625	Glutathione S-transferase	211
2918746995	213	63.71	12	213	2	152	2.1e-41	136.9	COG1183	Phosphatidylserine synthase	234
2918746996	178	95.54	8	155	6	155	7.7e-19	62.6	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
2918746997	113	81.36	1	112	7	102	1.3e-13	45.8	COG0640	DNA-binding transcriptional regulator, ArsR family	110
2918746998	299	83.23	5	298	48	325	4.6e-58	191.5	COG2367	Beta-lactamase class A	329
2918746999	433	99.52	1	433	1	419	3.0e-90	297.4	COG0766	UDP-N-acetylglucosamine enolpyruvyl transferase	421
2918747000	145	55.77	46	139	39	96	1.2e-10	31.2	COG2944	DNA-binding transcriptional regulator YiaG, XRE-type HTH domain	104
2918747001	206	88.03	1	206	23	228	3.3e-59	194.5	COG1272	Predicted membrane channel-forming protein YqfA, hemolysin III family	226
2918747002	303	98.67	2	300	2	298	8.0e-69	227.3	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918747003	151	91.67	7	151	10	141	3.0e-23	77.3	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
2918747004	216	97.44	54	209	3	154	4.6e-68	222.2	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
2918747005	331	99.3	1	331	1	284	4.5e-91	299.7	COG1319	CO or xanthine dehydrogenase, FAD-binding subunit	284
2918747006	746	98.93	9	746	5	741	0.0e+00	504.9	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
2918747010	619	97.64	7	604	14	591	0.0e+00	503.3	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
2918747011	314	98.34	2	299	2	297	3.4e-71	235	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918747012	276	97.77	4	273	6	268	5.0e-65	214.1	COG3384	Aromatic ring-opening dioxygenase, catalytic subunit, LigB family	268
2918747013	290	97.97	25	290	4	292	6.3e-30	99.4	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918747014	271	98.06	18	271	6	258	4.2e-35	116.1	COG3713	Outer membrane scaffolding protein for murein synthesis, MipA/OmpV family	258
2918747015	469	83.25	37	464	61	388	2.5e-50	166.8	COG0642	Signal transduction histidine kinase	336
2918747016	221	99.14	1	220	1	230	1.3e-69	228.6	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918747017	338	97.49	14	337	9	319	7.4e-76	249.8	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918747018	332	98.12	7	331	6	318	4.0e-82	270.4	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918747019	483	49.62	42	344	5	199	5.1e-07	22.6	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2918747020	280	99.59	27	272	1	245	8.5e-55	179.9	COG1414	DNA-binding transcriptional regulator, IclR family	246
2918747021	431	10.42	1	51	4	45	4.3e-98	28.4	COG1679	Predicted aconitase	403
2918747021	431	81.64	70	423	74	402	4.3e-98	293.3	COG1679	Predicted aconitase	403
2918747022	148	97.73	8	142	3	131	2.1e-32	106	COG1786	Swiveling domain associated with predicted aconitase	131
2918747023	566	95.16	2	560	25	574	0.0e+00	485.5	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
2918747024	377	98.89	6	377	5	360	2.0e-39	129.8	COG3203	Outer membrane protein (porin)	354
2918747025	325	95.3	4	323	13	316	1.0e-71	236.1	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918747026	314	95.94	40	312	1	307	4.9e-45	142	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
2918747027	268	59	6	194	31	184	1.1e-16	54.8	COG4544	Uncharacterized conserved protein	260
2918747028	449	76.74	10	399	22	308	9.0e-07	21.5	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
2918747029	1118	92.65	32	1116	3	1074	0.0e+00	915.3	COG0587	DNA polymerase III, alpha subunit	1139
2918747033	504	95.35	340	466	6	128	5.8e-38	123.7	COG0662	Mannose-6-phosphate isomerase, cupin superfamily	127
2918747033	504	99.4	5	331	2	334	2.7e-105	347	COG0836	Mannose-1-phosphate guanylyltransferase	333
2918747034	262	97.63	47	262	2	207	6.2e-49	161	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918747035	415	98.53	1	415	4	406	5.7e-36	119.6	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918747036	421	60.17	21	349	16	305	3.1e-13	43.9	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
2918747039	365	78.24	1	357	34	353	1.2e-16	56.3	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918747041	326	98.44	1	317	2	317	8.1e-68	223.8	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2918747042	220	81.33	4	220	39	221	4.8e-67	220	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
2918747043	764	23.87	368	486	352	462	4.0e-53	74.8	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
2918747043	764	25.16	11	187	14	130	4.0e-53	68	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
2918747043	764	27.53	202	367	141	268	4.0e-53	38.6	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
2918747043	764	76.92	499	760	34	253	7.0e-49	160.2	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
2918747044	393	18.88	278	363	134	180	2.5e-47	18.9	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
2918747044	393	76.71	62	280	26	216	2.5e-47	139.3	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
2918747046	272	46.67	7	157	26	123	7.8e-10	32.5	COG2945	Alpha/beta superfamily hydrolase	210
2918747047	253	71.75	27	226	24	183	4.0e-38	125.3	COG2091	Phosphopantetheinyl transferase	223
2918747048	1666	32.72	1310	1565	5	216	0.0e+00	37.1	COG1020	Non-ribosomal peptide synthetase component F	642
2918747048	1666	59.26	1557	1623	9	56	4.1e-07	10.9	COG0236	Acyl carrier protein	80
2918747048	1666	90.12	989	1063	8	80	4.1e-07	11.4	COG0236	Acyl carrier protein	80
2918747048	1666	97.99	243	897	9	643	0.0e+00	409.8	COG1020	Non-ribosomal peptide synthetase component F	642
2918747049	2429	23.93	5	436	874	1157	0.0e+00	1.4	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
2918747049	2429	86.44	795	1980	5	1030	0.0e+00	1027.2	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
2918747049	2429	99.31	1949	2375	3	431	3.0e-105	346.4	COG0001	Glutamate-1-semialdehyde aminotransferase	432
2918747055	874	99.32	1	874	5	880	0.0e+00	1122.1	COG0013	Alanyl-tRNA synthetase	879
2918747056	343	96.44	12	331	3	300	5.0e-54	178.1	COG1893	Ketopantoate reductase	307
2918747057	418	95.36	1	417	5	374	4.5e-92	303.7	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918747058	327	98.12	5	326	6	318	8.7e-78	256.1	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918747059	271	98.88	23	270	3	267	3.1e-60	198.6	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918747060	182	56.59	17	167	32	104	1.1e-09	32.5	COG0662	Mannose-6-phosphate isomerase, cupin superfamily	127
2918747061	291	98.31	27	291	2	291	5.0e-37	122.6	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918747062	278	99.59	19	264	2	246	9.2e-73	238.7	COG1414	DNA-binding transcriptional regulator, IclR family	246
2918747063	277	98.88	12	275	3	267	1.0e-55	183.8	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918747064	571	95.68	8	543	2	532	2.3e-122	403.7	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
2918747065	264	99.61	4	264	1	254	9.6e-85	278.5	COG1712	Predicted dinucleotide-utilizing enzyme	255
2918747066	492	98.12	8	485	5	474	0.0e+00	540.3	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918747067	323	15.38	109	208	163	204	3.8e-10	12.2	COG2514	Catechol-2,3-dioxygenase	265
2918747067	323	48.72	148	288	4	136	3.8e-10	27.7	COG2514	Catechol-2,3-dioxygenase	265
2918747068	330	97.49	5	329	7	317	2.2e-86	284.3	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918747069	385	90.84	5	374	5	361	5.6e-61	201.4	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2918747071	351	91.49	11	346	22	365	5.6e-53	173.1	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
2918747072	322	97.01	1	261	7	266	8.0e-60	197	COG1018	Ferredoxin-NADP reductase	266
2918747073	368	100	1	368	1	360	2.8e-35	116.2	COG3203	Outer membrane protein (porin)	354
2918747074	436	48.56	220	433	8	193	2.6e-21	22.2	COG0477	MFS family permease	338
2918747074	436	73.89	4	254	8	290	2.6e-21	55.1	COG0477	MFS family permease	338
2918747075	740	67.94	62	715	26	614	9.3e-102	335.3	COG0308	Aminopeptidase N	859
2918747077	251	86.93	2	246	27	272	1.6e-25	84.4	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918747078	272	98.88	9	270	3	266	5.2e-24	79.4	COG0725	ABC-type molybdate transport system, periplasmic component	258
2918747079	257	79.55	114	256	21	125	1.5e-27	90.3	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918747080	303	95.68	4	293	7	294	4.0e-19	63.3	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918747081	94	19.57	23	91	37	82	3.1e-03	11.6	COG3471	Predicted secreted (periplasmic) protein	235
2918747082	383	69.29	24	379	116	388	1.1e-48	161.2	COG0642	Signal transduction histidine kinase	336
2918747083	301	54.5	12	142	3	117	4.4e-38	56.2	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918747083	301	55.45	181	299	89	205	4.4e-38	68.2	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918747084	1129	83.76	528	899	56	385	3.7e-67	222.3	COG0642	Signal transduction histidine kinase	336
2918747084	1129	90.18	21	486	24	427	2.6e-24	80.3	COG1457	Purine-cytosine permease or related protein	442
2918747084	1129	93.23	915	1041	7	130	7.2e-27	86.9	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918747085	421	93.17	21	407	9	349	6.9e-54	177.7	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918747086	304	99	6	304	2	299	1.0e-82	272.6	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2918747087	402	97.21	10	354	8	321	3.8e-73	241	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918747088	247	95.7	1	247	9	253	1.0e-106	350.6	COG4674	ABC-type uncharacterized transport system, ATPase component	249
2918747089	233	99.16	3	233	2	236	1.5e-84	277.5	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2918747090	410	97.44	12	389	5	309	1.9e-90	297.5	COG2421	Acetamidase/formamidase	305
2918747091	115	52.44	1	70	8	50	1.0e-05	19.6	COG2331	Predicted nucleic acid-binding protein, contains Zn-ribbon domain	82
2918747094	759	92.33	48	472	1	385	2.7e-102	337.4	COG1472	Periplasmic beta-glucosidase and related glycosidases	397
2918747095	326	97.18	5	325	8	317	1.5e-96	317.8	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918747096	408	47.58	5	118	43	101	8.6e-03	8.1	COG1145	Ferredoxin	99
2918747097	475	74.38	2	475	9	429	6.0e-39	127.9	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
2918747098	308	98.67	1	297	1	297	1.7e-51	170.4	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918747099	255	91.52	13	233	3	207	4.4e-52	171.4	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
2918747100	196	67.74	17	182	21	146	5.6e-30	98.7	COG4341	Predicted HD phosphohydrolase	186
2918747101	239	97.25	15	229	2	213	9.3e-35	114.6	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2918747102	386	90.98	26	382	5	337	3.6e-37	122.7	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918747103	245	98.24	25	245	2	224	6.0e-75	246.3	COG0220	tRNA G46 methylase TrmB	227
2918747104	308	52.92	1	293	11	264	5.7e-70	231.3	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
2918747105	360	96.99	20	360	5	326	2.0e-65	215.8	COG3380	Predicted NAD/FAD-dependent oxidoreductase	331
2918747106	317	97.34	8	310	4	296	3.9e-48	159.2	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918747107	233	88.21	1	233	1	247	2.0e-61	202.6	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
2918747108	139	92.36	1	139	5	137	6.8e-38	124.9	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
2918747109	183	13.15	1	36	3	30	1.6e-26	10.4	COG0655	Multimeric flavodoxin WrbA	207
2918747109	183	66.67	34	183	69	210	1.6e-26	76.3	COG0655	Multimeric flavodoxin WrbA	207
2918747110	307	98.57	1	279	4	279	3.0e-84	277.4	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
2918747111	263	78.25	1	256	4	244	2.8e-79	260.9	COG1054	Predicted sulfurtransferase	308
2918747112	1172	98.53	1	1169	3	1142	0.0e+00	1311	COG0587	DNA polymerase III, alpha subunit	1139
2918747113	308	86.86	16	305	9	246	3.2e-11	37.3	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
2918747114	145	94.96	1	143	4	135	1.8e-38	126.3	COG0848	Biopolymer transport protein ExbD	137
2918747115	240	98.15	10	225	2	213	5.5e-69	227	COG0811	Biopolymer transport protein ExbB/TolQ	216
2918747116	152	93.53	1	144	7	136	1.2e-39	130	COG0824	Acyl-CoA thioesterase FadM	137
2918747117	398	98.74	5	396	3	393	1.4e-110	364.5	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
2918747118	181	94.12	25	169	8	151	6.7e-33	108.2	COG0781	Transcription termination factor NusB	151
2918747119	156	95.39	6	154	7	151	2.3e-51	168.1	COG0054	6,7-dimethyl-8-ribityllumazine synthase (Riboflavin synthase beta chain)	152
2918747120	384	85.71	221	383	3	170	9.0e-27	88.1	COG0807	GTP cyclohydrolase II	193
2918747120	384	98.52	18	221	3	202	2.5e-84	276.3	COG0108	3,4-dihydroxy-2-butanone 4-phosphate synthase	203
2918747121	221	95.12	1	211	1	195	3.5e-65	213.4	COG0307	Riboflavin synthase alpha chain	204
2918747122	365	74.51	1	139	12	125	3.8e-15	50.3	COG0590	tRNA(Arg) A34 adenosine deaminase TadA	152
2918747122	365	99.09	142	361	2	219	3.5e-62	204.2	COG1985	Pyrimidine reductase, riboflavin biosynthesis	218
2918747123	149	75	1	147	15	152	1.1e-15	52.5	COG4970	Tfp pilus assembly protein FimT	181
2918747124	163	65.45	1	140	14	121	5.3e-19	63.2	COG4967	Tfp pilus assembly protein PilV	162
2918747125	265	24.36	3	214	6	43	2.7e-05	18	COG2165	Type II secretory pathway, pseudopilin PulG	149
2918747126	232	92.35	4	227	7	187	5.1e-24	75.7	COG4726	Tfp pilus assembly protein PilX	196
2918747127	1129	67.49	123	1070	264	973	1.1e-122	404.3	COG3419	Tfp pilus assembly protein, tip-associated adhesin PilY1	1036
2918747128	154	97.12	10	152	5	139	1.2e-37	124	COG4968	Tfp pilus assembly protein PilE	139
2918747129	147	93.59	1	147	1	146	6.7e-60	196.2	COG1327	Transcriptional regulator NrdR, contains Zn-ribbon and ATP-cone domains	156
2918747130	414	98.31	3	414	7	414	0.0e+00	632.6	COG0112	Glycine/serine hydroxymethyltransferase	413
2918747135	97	92.31	1	97	8	103	5.0e-34	110.9	COG4274	Uncharacterized protein, contains GYD domain	104
2918747136	263	91.73	1	263	6	249	3.5e-62	204.9	COG3228	Mlc titration factor MtfA, regulates ptsG expression	266
2918747137	258	90.46	23	256	3	220	2.2e-48	159.2	COG2908	UDP-2,3-diacylglucosamine pyrophosphatase LpxH	237
2918747138	170	94.9	6	169	6	154	2.4e-48	158.7	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
2918747139	199	98.73	38	199	2	156	6.4e-52	170.3	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
2918747140	196	23.08	104	189	116	175	2.4e-11	11.4	COG5010	Flp pilus assembly protein TadD, contains TPR repeats	257
2918747140	196	38.46	21	156	112	211	2.4e-11	36	COG5010	Flp pilus assembly protein TadD, contains TPR repeats	257
2918747141	458	99.35	2	457	2	463	0.0e+00	589.8	COG0215	Cysteinyl-tRNA synthetase	464
2918747142	217	73.7	5	213	65	277	1.1e-55	183.6	COG0122	3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase	285
2918747143	326	99.05	3	319	3	316	0.0e+00	493.3	COG0825	Acetyl-CoA carboxylase alpha subunit	317
2918747144	325	75	3	284	26	256	8.3e-59	193.5	COG0037	tRNA(Ile)-lysidine synthase TilS/MesJ	298
2918747145	422	99.55	1	418	1	441	0.0e+00	467.6	COG0527	Aspartokinase	447
2918747147	347	99.04	18	339	2	310	1.8e-64	212.4	COG1907	Predicted archaeal sugar kinase	312
2918747148	305	30.51	66	286	118	218	3.1e-06	21.3	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2918747149	380	94.36	1	380	11	378	3.5e-37	122.7	COG2232	Predicted ATP-dependent carboligase, ATP-grasp superfamily	389
2918747150	335	96.82	13	331	1	304	1.2e-84	278.8	COG3252	Methenyltetrahydromethanopterin cyclohydrolase	314
2918747151	316	73.02	37	300	77	306	4.9e-42	138.3	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
2918747152	313	95.17	6	295	7	282	2.8e-21	69.9	COG1767	Triphosphoribosyl-dephospho-CoA synthetase	288
2918747153	170	95.29	6	170	3	164	2.2e-60	198	COG1795	Formaldehyde-activating enzyme nesessary for methanogenesis	170
2918747154	173	96.69	30	149	2	118	6.5e-30	98.4	COG1539	Dihydroneopterin aldolase	121
2918747155	684	99.02	5	680	5	610	0.0e+00	599.3	COG3284	Transcriptional regulator of acetoin/glycerol metabolism	606
2918747156	217	14.52	162	204	204	238	1.9e-31	7.1	COG1036	Archaeal flavoprotein	187
2918747156	217	57.68	30	167	9	147	1.9e-31	95.1	COG1036	Archaeal flavoprotein	187
2918747157	492	7.91	94	202	31	52	2.4e-12	5.5	COG0294	Dihydropteroate synthase	274
2918747157	492	9.35	395	444	252	277	2.4e-12	13	COG0294	Dihydropteroate synthase	274
2918747157	492	42.09	246	388	75	191	2.4e-12	20.1	COG0294	Dihydropteroate synthase	274
2918747158	193	91.5	1	182	13	195	2.2e-16	54.8	COG2457	Uncharacterized protein	199
2918747159	234	35.32	125	225	148	230	1.4e-31	48.3	COG1891	Uncharacterized protein, UPF0264 family	235
2918747159	234	37.45	3	114	2	89	1.4e-31	54.7	COG1891	Uncharacterized protein, UPF0264 family	235
2918747160	199	65.57	1	181	1	139	6.0e-27	89.3	COG2054	Uncharacterized archaeal kinase related to aspartokinase	212
2918747161	366	87.58	5	342	5	293	1.9e-58	192.5	COG1548	Uncharacterized protein, hydantoinase/oxoprolinase family	330
2918747162	329	90.23	3	318	2	278	1.1e-37	124.3	COG1821	Predicted ATP-dependent carboligase, ATP-grasp superfamily	307
2918747163	244	93.91	5	241	1	216	9.0e-33	107.8	COG1411	Uncharacterized protein related to proFAR isomerase (HisA)	229
2918747164	407	35.43	12	174	7	158	2.8e-19	44.3	COG1029	Formylmethanofuran dehydrogenase subunit B	429
2918747164	407	51.05	182	402	210	428	2.8e-19	17.1	COG1029	Formylmethanofuran dehydrogenase subunit B	429
2918747165	561	93.74	1	533	2	540	0.0e+00	489.4	COG1229	Formylmethanofuran dehydrogenase subunit A	575
2918747166	317	99.66	4	310	2	297	7.4e-100	328.7	COG2037	Formylmethanofuran:tetrahydromethanopterin formyltransferase	297
2918747167	276	77.95	1	245	9	213	1.3e-45	150.3	COG2218	Formylmethanofuran dehydrogenase subunit C	264
2918747168	177	88.24	6	176	13	162	7.3e-43	141	COG1795	Formaldehyde-activating enzyme nesessary for methanogenesis	170
2918747169	630	62.96	43	416	164	457	1.6e-101	335.2	COG0147	Anthranilate/para-aminobenzoate synthases component I	462
2918747170	223	92.92	1	220	5	201	7.1e-46	150.8	COG0560	Phosphoserine phosphatase	212
2918747171	215	99.53	8	214	1	210	4.1e-60	197.6	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918747172	459	86.4	3	451	52	375	1.8e-46	152.5	COG4585	Signal transduction histidine kinase	365
2918747173	331	92.88	4	321	5	278	2.9e-35	116.9	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918747174	307	94.51	1	306	4	261	4.5e-26	85.9	COG1235	Phosphoribosyl 1,2-cyclic phosphodiesterase	269
2918747175	254	93.39	18	254	5	230	5.9e-73	239.9	COG5424	Pyrroloquinoline quinone (PQQ) biosynthesis protein C	242
2918747177	383	94.13	3	341	20	356	2.9e-61	202.1	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
2918747178	513	69	55	215	30	167	5.1e-15	49.9	COG5620	Uncharacterized protein	200
2918747180	183	51.36	26	172	103	291	1.4e-04	16.7	COG0457	Tetratricopeptide (TPR) repeat	291
2918747183	291	53	17	288	175	395	3.6e-11	36.9	COG1721	Uncharacterized conserved protein, DUF58 family, contains vWF domain	416
2918747184	339	94.55	2	339	16	327	1.6e-54	179.8	COG0714	MoxR-like ATPase	329
2918747185	181	71.92	35	145	3	107	6.7e-04	13.3	COG3427	Carbon monoxide dehydrogenase subunit G	146
2918747186	327	49.13	24	216	97	294	1.1e-52	109.3	COG3391	DNA-binding beta-propeller fold protein YncE	381
2918747186	327	56.33	138	320	83	309	1.1e-52	77.2	COG3391	DNA-binding beta-propeller fold protein YncE	381
2918747190	134	44.51	16	132	72	144	4.6e-07	24.9	COG2010	Cytochrome c, mono- and diheme variants	150
2918747191	608	80.72	14	608	150	773	0.0e+00	504.1	COG4993	Glucose dehydrogenase	773
2918747192	237	73.86	1	232	5	230	2.1e-72	238.7	COG1131	ABC-type multidrug transport system, ATPase component	293
2918747193	332	24.07	223	331	83	179	1.5e-37	25.9	COG3391	DNA-binding beta-propeller fold protein YncE	381
2918747193	332	36.97	130	281	111	259	1.5e-37	69.5	COG3391	DNA-binding beta-propeller fold protein YncE	381
2918747194	393	24.86	60	240	96	186	3.2e-09	19.6	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918747194	393	26.5	249	362	250	346	3.2e-09	9.4	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918747195	295	78.84	20	278	47	277	4.9e-18	59.8	COG0842	ABC-type multidrug transport system, permease component	286
2918747196	337	97.81	18	334	7	318	2.4e-72	238.3	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918747197	765	97.86	2	762	16	793	9.7e-51	167.7	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2918747198	325	97.67	7	303	3	296	3.3e-70	231.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918747199	485	99.3	15	469	3	428	0.0e+00	569	COG1850	Ribulose 1,5-bisphosphate carboxylase, large subunit, or a RuBisCO-like protein	429
2918747200	139	82.68	1	129	8	112	4.6e-39	127.7	COG4451	Ribulose bisphosphate carboxylase small subunit	127
2918747201	307	4.47	68	99	200	221	9.3e-08	10	COG0606	Predicted ATPase with chaperone activity	490
2918747201	307	35.77	98	294	261	436	9.3e-08	14.7	COG0606	Predicted ATPase with chaperone activity	490
2918747202	267	83.71	2	220	2	186	1.0e-35	118.1	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
2918747203	227	96.36	1	217	4	215	2.6e-89	292.6	COG0036	Pentose-5-phosphate-3-epimerase	220
2918747204	243	95.95	7	224	4	216	2.9e-42	139.5	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
2918747205	357	99.39	6	338	2	327	7.0e-129	424	COG0158	Fructose-1,6-bisphosphatase	326
2918747206	292	99.65	1	289	1	288	0.0e+00	485.2	COG3954	Phosphoribulokinase	289
2918747207	679	99.1	4	668	6	662	0.0e+00	936.2	COG0021	Transketolase	663
2918747208	338	99.65	1	329	1	287	9.9e-109	357.7	COG0191	Fructose/tagatose bisphosphate aldolase	286
2918747210	278	94.01	12	273	15	265	1.0e-82	272	COG1526	Formate dehydrogenase assembly factor FdhD	266
2918747211	957	21.78	16	240	3	215	0.0e+00	278.3	COG3383	Predicted molibdopterin-dependent oxidoreductase YjgC	978
2918747211	957	71.17	236	953	263	958	0.0e+00	962.3	COG3383	Predicted molibdopterin-dependent oxidoreductase YjgC	978
2918747212	518	98.11	94	515	2	417	0.0e+00	530.1	COG1894	NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F)	424
2918747213	154	84.34	2	153	25	164	1.5e-42	139.4	COG1905	NADH:ubiquinone oxidoreductase 24 kD subunit (chain E)	160
2918747214	371	85.5	4	122	3	114	5.2e-21	69.1	COG2005	DNA-binding transcriptional regulator ModE (molybdenum-dependent)	130
2918747214	371	92.83	123	350	14	220	3.6e-52	171.3	COG1910	Periplasmic molybdate-binding protein/domain	223
2918747216	268	81.85	5	254	48	268	4.9e-80	263.4	COG2326	Polyphosphate kinase 2, PPK2 family	270
2918747217	144	89	1	97	8	96	2.9e-31	102.4	COG1188	Ribosomal 50S subunit-recycling heat shock protein, contains S4 domain	100
2918747218	473	84.26	85	471	56	387	9.1e-50	165.2	COG0642	Signal transduction histidine kinase	336
2918747219	226	99.14	1	226	1	230	6.5e-66	216.6	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918747220	319	97.18	4	319	8	317	3.1e-90	297.1	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918747222	504	98.02	1	503	1	494	0.0e+00	627.7	COG3333	TctA family transporter	504
2918747223	1036	99.9	2	1006	1	1013	0.0e+00	983.2	COG0841	Multidrug efflux pump subunit AcrB	1009
2918747224	409	95.9	1	380	7	380	2.6e-46	153.1	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918747225	498	97.83	17	486	3	452	3.4e-103	340.5	COG1538	Outer membrane protein TolC	457
2918747226	240	84.69	7	236	9	185	2.1e-21	71.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918747228	514	79.03	11	512	114	554	0.0e+00	435.6	COG3829	Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding Fis domains	560
2918747230	397	95.36	11	379	5	353	1.3e-36	120.9	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918747231	485	20.13	24	200	141	203	1.6e-13	21.1	COG3509	Poly(3-hydroxybutyrate) depolymerase	312
2918747231	485	24.92	212	334	41	118	1.6e-13	31.6	COG3509	Poly(3-hydroxybutyrate) depolymerase	312
2918747232	255	98.03	1	249	5	253	1.7e-83	274.4	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2918747233	242	99.16	4	240	2	236	3.4e-80	263.2	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2918747234	326	97.67	26	326	3	296	9.9e-68	223.4	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2918747235	355	98.45	13	355	5	322	6.4e-75	246.9	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918747236	295	95.93	9	294	2	284	5.9e-27	89.7	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918747237	168	86.53	1	168	26	192	1.3e-63	209	COG3812	Uncharacterized protein	193
2918747238	354	98.13	16	340	5	319	1.9e-107	353.7	COG0276	Protoheme ferro-lyase (ferrochelatase)	320
2918747239	243	87.88	16	240	2	204	1.7e-32	107.8	COG1011	FMN phosphatase YigB, HAD superfamily	229
2918747242	419	69.57	1	355	11	321	7.1e-32	104.2	COG2907	Predicted NAD/FAD-binding protein	447
2918747243	279	96.19	1	279	10	287	6.6e-91	299.3	COG1562	Phytoene/squalene synthetase	288
2918747244	303	92.04	11	294	20	285	1.4e-42	140.4	COG1562	Phytoene/squalene synthetase	288
2918747245	640	97.13	14	640	16	624	0.0e+00	788.4	COG3158	K+ transporter	627
2918747246	397	94.1	4	361	9	375	2.4e-51	169.9	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918747247	1052	99.9	16	1041	1	1013	0.0e+00	913.2	COG0841	Multidrug efflux pump subunit AcrB	1009
2918747249	437	99.11	1	437	1	444	0.0e+00	454.6	COG0544	FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)	441
2918747250	202	95.5	5	202	3	193	6.0e-91	298.3	COG0740	ATP-dependent protease ClpP, protease subunit	200
2918747251	421	98.53	16	421	1	403	0.0e+00	675.3	COG1219	ATP-dependent protease Clp, ATPase subunit	408
2918747252	813	98.6	6	785	8	780	0.0e+00	1129.4	COG0466	ATP-dependent Lon protease, bacterial type	782
2918747257	439	96.03	11	438	12	446	1.5e-59	196.3	COG2270	MFS-type transporter involved in bile tolerance, Atg22 family	438
2918747259	264	94.78	1	264	5	258	4.4e-71	233.9	COG0796	Glutamate racemase	269
2918747260	517	97.66	1	308	3	294	1.5e-113	373.1	COG1951	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain	297
2918747260	517	97.84	321	506	2	182	7.1e-70	228.4	COG1838	Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain	184
2918747261	335	96.07	2	334	10	302	4.0e-73	240.5	COG2113	ABC-type proline/glycine betaine transport system, periplasmic component	302
2918747262	383	95.88	60	348	10	288	6.2e-112	368.2	COG4176	ABC-type proline/glycine betaine transport system, permease component	290
2918747263	417	98.97	1	398	3	386	0.0e+00	519.6	COG4175	ABC-type proline/glycine betaine transport system, ATPase component	386
2918747264	465	99.35	5	465	2	460	0.0e+00	759.6	COG0114	Fumarate hydratase class II	462
2918747265	205	99.53	2	205	2	211	1.7e-74	244.7	COG2910	Putative NADH-flavin reductase	211
2918747266	302	99.34	2	299	2	300	3.9e-74	244.7	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918747267	211	93.49	12	211	8	165	1.9e-51	163.4	COG2862	Uncharacterized membrane protein YqhA	169
2918747269	52	14.72	1	52	252	295	1.1e-06	22.5	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
2918747270	320	96.87	1	319	8	316	6.5e-90	296.1	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918747271	451	98.66	14	421	4	371	6.9e-83	273.1	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
2918747272	340	86.23	1	319	23	335	1.1e-64	213.6	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
2918747273	505	93.26	22	503	28	456	1.3e-110	364.9	COG1538	Outer membrane protein TolC	457
2918747274	1068	99.7	2	1037	1	1011	0.0e+00	1138.7	COG0841	Multidrug efflux pump subunit AcrB	1009
2918747275	391	95.9	1	377	7	380	1.4e-55	183.6	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918747276	314	98.67	2	301	2	298	2.7e-69	228.9	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918747277	462	99.34	2	450	3	454	0.0e+00	474.1	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
2918747278	302	97.01	3	300	5	296	2.2e-74	245.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918747279	114	77.42	8	110	19	114	4.4e-21	69.9	COG0599	Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family	124
2918747280	363	98.35	1	360	3	359	1.9e-97	321.3	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
2918747281	204	98.6	1	200	1	212	3.1e-42	139.4	COG0625	Glutathione S-transferase	211
2918747282	291	95.35	51	271	3	207	2.2e-52	172.5	COG0625	Glutathione S-transferase	211
2918747283	303	97.76	2	245	6	267	4.2e-46	150.7	COG1018	Ferredoxin-NADP reductase	266
2918747284	307	23.56	193	276	65	105	2.0e-12	7	COG3576	Predicted flavin-nucleotide-binding protein, pyridoxine 5'-phosphate oxidase superfamily	173
2918747284	307	88.51	6	203	1	154	2.0e-12	33.6	COG3576	Predicted flavin-nucleotide-binding protein, pyridoxine 5'-phosphate oxidase superfamily	173
2918747286	312	98.34	2	298	3	298	4.9e-58	191.9	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918747292	555	94.46	2	555	32	560	0.0e+00	548.2	COG2831	Hemolysin activation/secretion protein	554
2918747295	294	98.01	7	294	2	296	2.7e-55	182.9	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918747296	424	91.84	5	424	32	425	2.1e-120	396.4	COG1850	Ribulose 1,5-bisphosphate carboxylase, large subunit, or a RuBisCO-like protein	429
2918747297	467	99.28	2	460	2	413	3.9e-73	241.2	COG3395	Uncharacterized conserved protein YgbK, DUF1537 family	413
2918747298	339	96.08	5	336	8	326	8.5e-92	302.4	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
2918747299	623	88.14	16	179	4	159	3.9e-35	115.6	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
2918747299	623	98.42	249	623	1	373	1.2e-96	318.7	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
2918747300	256	98.51	3	251	4	267	7.0e-75	246.6	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918747301	157	74.51	1	150	12	125	1.7e-33	110.5	COG0590	tRNA(Arg) A34 adenosine deaminase TadA	152
2918747302	326	97.49	7	326	7	317	1.5e-75	248.8	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918747303	265	97.92	10	239	5	239	2.1e-84	270.9	COG4312	Predicted dithiol-disulfide oxidoreductase, DUF899 family	247
2918747304	514	60.8	327	503	60	211	2.0e-02	6	COG3063	Tfp pilus assembly protein PilF	250
2918747304	514	94.08	100	251	8	150	9.6e-46	149.2	COG5616	TolB amino-terminal domain (function unknown)	152
2918747305	138	90.14	2	138	15	142	8.6e-41	133.5	COG4101	Uncharacterized protein, RmlC-like cupin domain	142
2918747306	163	67.65	8	159	25	116	2.4e-06	22	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
2918747307	46	16.27	1	39	4	37	6.5e-10	33.6	COG2860	Uncharacterized membrane protein YeiH	209
2918747308	162	77.16	4	149	29	153	4.5e-09	31.6	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2918747309	298	96.68	3	298	2	292	1.7e-65	216.4	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918747310	292	20	219	292	250	313	5.3e-67	62.2	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
2918747310	292	64.06	9	225	10	214	5.3e-67	156.9	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
2918747312	157	71.96	13	145	27	162	1.1e-14	49.2	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
2918747313	648	89.6	198	645	40	375	2.4e-45	147.3	COG4585	Signal transduction histidine kinase	365
2918747314	306	97.32	4	300	5	295	4.7e-53	174.3	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
2918747315	395	90.35	32	393	31	367	2.0e-84	278	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
2918747316	303	97.06	1	300	5	301	1.4e-77	255.3	COG3734	2-keto-3-deoxy-galactonokinase	306
2918747317	198	91.47	1	198	14	206	6.2e-55	180.5	COG0800	2-keto-3-deoxy-6-phosphogluconate aldolase	211
2918747318	332	97.49	6	331	8	318	1.5e-81	268.5	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918747319	330	97.18	12	329	8	317	4.1e-69	227.6	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918747320	590	97.97	39	284	2	242	5.1e-67	219.7	COG1414	DNA-binding transcriptional regulator, IclR family	246
2918747320	590	98.38	289	588	5	308	5.1e-86	282.8	COG3386	Sugar lactone lactonase YvrE	307
2918747321	197	68.92	25	150	9	110	1.9e-24	80.2	COG3710	DNA-binding winged helix-turn-helix (wHTH) domain	148
2918747324	250	91.19	2	250	22	290	1.4e-19	65.1	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918747325	351	79.08	56	335	70	345	2.2e-77	254.8	COG0820	Adenine C2-methylase RlmN of 23S rRNA A2503 and tRNA A37	349
2918747326	506	98.61	1	499	1	497	0.0e+00	587.7	COG3333	TctA family transporter	504
2918747328	420	45.17	232	419	14	186	4.1e-08	16.3	COG0477	MFS family permease	338
2918747328	420	71.02	15	287	8	279	4.1e-08	13.4	COG0477	MFS family permease	338
2918747329	486	49.17	5	157	124	242	1.8e-15	23.8	COG2202	PAS domain	232
2918747329	486	77.27	98	317	56	242	1.8e-15	38.5	COG2202	PAS domain	232
2918747329	486	92.9	305	485	6	175	2.3e-37	122	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2918747330	119	91.67	2	108	9	107	1.4e-08	29.5	COG5569	Periplasmic Cu and Ag efflux protein CusF	108
2918747331	790	96.96	2	790	13	777	1.5e-126	418	COG0417	DNA polymerase elongation subunit (family B)	792
2918747333	133	59.21	29	124	60	149	4.2e-20	66.8	COG0782	Transcription elongation factor, GreA/GreB family	151
2918747335	160	92.47	11	122	8	142	8.7e-08	25.6	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2918747336	133	96.83	2	127	2	123	9.0e-52	168.9	COG0853	Aspartate 1-decarboxylase	126
2918747337	109	15.17	1	109	626	738	2.0e-27	90.8	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
2918747338	242	66.81	32	236	58	212	1.8e-15	52.6	COG0671	Membrane-associated phospholipid phosphatase	232
2918747340	457	82.99	54	456	57	383	1.5e-50	167.6	COG0642	Signal transduction histidine kinase	336
2918747341	228	98.71	2	225	2	230	1.2e-61	202.6	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918747342	281	89.15	29	281	29	258	3.1e-33	110	COG3713	Outer membrane scaffolding protein for murein synthesis, MipA/OmpV family	258
2918747343	266	95.82	6	241	9	237	3.6e-55	181.5	COG2188	DNA-binding transcriptional regulator, GntR family	236
2918747344	362	97.78	8	362	9	360	1.8e-34	113.5	COG3203	Outer membrane protein (porin)	354
2918747347	327	96.55	6	326	10	317	7.0e-72	236.8	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918747348	353	97.16	3	350	7	348	1.8e-58	192.5	COG3180	Uncharacterized membrane protein AbrB, regulator of aidB expression	352
2918747349	557	96.65	13	557	8	556	2.0e-129	427.1	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2918747350	417	48.83	9	221	8	194	1.6e-20	36.2	COG0477	MFS family permease	338
2918747350	417	51.17	221	416	6	201	1.6e-20	38.3	COG0477	MFS family permease	338
2918747351	347	98.01	4	299	3	297	9.9e-58	190.8	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918747352	558	97.35	7	554	2	551	3.0e-121	399.8	COG0146	N-methylhydantoinase B/oxoprolinase/acetone carboxylase, alpha subunit	563
2918747353	710	99.41	3	691	3	677	0.0e+00	575.2	COG0145	N-methylhydantoinase A/oxoprolinase/acetone carboxylase, beta subunit	674
2918747354	339	86.2	6	333	32	312	4.8e-86	283	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
2918747355	467	96.93	4	456	7	448	2.7e-119	393.2	COG2079	2-methylcitrate dehydratase PrpD	453
2918747357	108	45.38	29	108	2	60	1.5e-07	27.2	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918747358	291	60.53	3	288	84	267	1.0e-15	52.7	COG2159	Predicted metal-dependent hydrolase, TIM-barrel fold	293
2918747359	309	42.47	153	287	2	63	1.1e-06	23.9	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2918747360	298	81.68	17	291	48	270	1.1e-70	232.7	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
2918747361	131	96.32	1	131	5	135	9.2e-30	98	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
2918747362	350	98.57	1	347	3	346	3.8e-100	329.7	COG2055	Malate/lactate/ureidoglycolate dehydrogenase, LDH2 family	349
2918747363	140	60.31	22	125	33	111	8.3e-10	33	COG1917	Cupin domain protein related to quercetin dioxygenase	131
2918747364	258	96.51	1	254	6	254	1.7e-73	241.8	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2918747365	260	90.44	2	246	17	243	2.8e-85	280.3	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2918747366	338	80.3	1	314	11	279	5.1e-36	119.2	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918747367	533	86.77	7	369	2	342	5.4e-58	192.1	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2918747368	245	97.39	5	240	2	262	8.3e-54	177.6	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918747369	223	92.24	2	223	9	222	5.9e-55	180.8	COG1802	DNA-binding transcriptional regulator, GntR family	230
2918747370	329	75.76	206	328	24	123	1.4e-22	74	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918747371	265	99.25	3	251	2	267	1.8e-58	192.9	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918747372	319	98.13	1	259	6	268	5.2e-51	168	COG1018	Ferredoxin-NADP reductase	266
2918747373	354	81.82	226	354	17	124	2.7e-18	60.2	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918747374	353	92.29	7	352	26	372	2.6e-55	182.7	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
2918747375	390	94.81	12	371	8	354	5.1e-43	142	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918747376	242	99.16	5	242	2	236	5.2e-76	249.6	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2918747377	251	99.61	1	247	2	254	7.8e-86	282.1	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2918747378	334	96.28	23	331	9	319	4.0e-72	237.7	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918747379	306	97.34	2	306	4	296	2.3e-69	228.8	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2918747380	455	59.84	11	384	4	228	9.8e-51	167.7	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
2918747381	178	91.46	19	178	3	152	7.9e-20	66.2	COG5517	3-phenylpropionate/cinnamic acid dioxygenase, small subunit	164
2918747382	200	88.35	1	193	3	184	2.7e-33	110	COG1335	Nicotinamidase-related amidase	205
2918747383	316	75.76	184	314	22	121	1.2e-18	61.5	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918747384	342	50.75	239	313	49	116	1.8e-19	19.4	COG3335	Transposase	132
2918747384	342	66.91	5	122	4	96	1.0e-09	31	COG3415	Transposase	138
2918747384	342	99.25	147	274	2	134	1.8e-19	51.1	COG3335	Transposase	132
2918747385	389	95.63	12	372	5	354	1.2e-42	140.8	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918747386	262	92.2	4	260	23	294	3.9e-23	75.9	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918747387	395	95.9	16	382	4	354	1.5e-32	106.1	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918747388	228	38.06	18	220	176	395	2.7e-20	67	COG0747	ABC-type transport system, periplasmic component	556
2918747389	136	32.92	8	128	11	115	2.5e-26	87	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918747390	507	95.59	10	219	5	199	3.7e-24	79.6	COG1014	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, gamma subunit	203
2918747391	750	97.2	9	721	16	641	0.0e+00	678.5	COG4231	TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit	640
2918747392	259	98.17	14	259	3	217	1.6e-67	221.6	COG1878	Kynurenine formamidase	218
2918747393	531	97.18	6	531	5	487	1.4e-124	411.5	COG1233	Phytoene dehydrogenase-related protein	487
2918747396	141	57.84	16	129	14	120	4.3e-22	73.1	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
2918747397	74	24.65	1	74	208	277	1.2e-14	49.2	COG2801	Transposase InsO and inactivated derivatives	232
2918747399	291	98.64	17	288	3	293	2.5e-36	120.5	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918747401	297	91.25	212	291	5	77	4.8e-14	45.8	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2918747402	301	98.01	4	301	3	297	6.6e-49	161.9	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918747403	325	95.92	8	323	7	312	3.0e-74	244.4	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918747404	301	97.63	20	292	7	294	2.5e-36	120.4	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918747405	618	96.65	33	564	13	561	1.3e-75	249.3	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2918747407	310	98.34	8	310	2	297	1.5e-54	180.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918747408	418	19.84	304	414	353	450	6.8e-95	46	COG2272	Carboxylesterase type B	491
2918747408	418	62.15	1	314	7	313	6.8e-95	266.4	COG2272	Carboxylesterase type B	491
2918747409	316	96.55	1	315	10	317	1.1e-81	269.1	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918747410	400	100	1	400	1	360	1.2e-47	157.3	COG3203	Outer membrane protein (porin)	354
2918747413	64	37.4	12	64	61	109	5.3e-10	33.9	COG1917	Cupin domain protein related to quercetin dioxygenase	131
2918747414	559	89.24	7	332	7	288	1.7e-70	231.9	COG4227	Antirestriction protein ArdC	316
2918747417	190	53.85	8	123	1	70	1.1e-15	53	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918747418	83	71.43	15	74	13	62	1.3e-16	54.7	COG3311	Predicted DNA-binding transcriptional regulator AlpA	70
2918747419	1136	90.3	230	1090	10	800	0.0e+00	561.1	COG4096	Type I site-specific restriction endonuclease, part of a restriction-modification system	875
2918747420	526	82.22	2	436	7	436	3.1e-79	261.2	COG0286	Type I restriction-modification system, DNA methylase subunit	489
2918747421	347	100	112	262	1	159	3.5e-46	151.1	COG4804	Predicted nuclease of restriction endonuclease-like (RecB) superfamily,  DUF1016 family	159
2918747422	567	77.78	4	346	67	381	2.2e-31	103.6	COG0732	Restriction endonuclease S subunit	391
2918747423	657	20.92	296	373	107	156	7.5e-04	3.1	COG1579	Predicted  nucleic acid-binding protein, contains Zn-ribbon domain	239
2918747423	657	43.51	390	522	32	135	7.5e-04	13.2	COG1579	Predicted  nucleic acid-binding protein, contains Zn-ribbon domain	239
2918747424	322	98.02	214	314	2	100	3.1e-21	69.9	COG3586	Predicted transport protein	101
2918747425	1040	92.65	3	1038	3	1074	0.0e+00	961.4	COG0587	DNA polymerase III, alpha subunit	1139
2918747426	449	83.69	30	417	38	350	3.5e-08	27.2	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
2918747427	280	57.85	18	207	33	183	1.4e-14	48.1	COG4544	Uncharacterized conserved protein	260
2918747428	307	69.47	94	304	28	184	3.3e-15	50.3	COG2135	Putative SOS response-associated peptidase YedK	226
2918747430	311	96.77	1	277	7	276	4.1e-77	253.5	COG1273	Non-homologous end joining protein Ku, dsDNA break repair	278
2918747433	860	95.73	78	549	1	471	6.3e-99	326.4	COG1793	ATP-dependent DNA ligase	444
2918747433	860	97.68	558	856	3	297	1.1e-98	324.1	COG3285	Eukaryotic-type DNA primase	299
2918747434	83	22.54	1	82	169	232	1.8e-10	35.5	COG2801	Transposase InsO and inactivated derivatives	232
2918747435	314	90.19	1	313	11	295	9.9e-73	239.5	COG4227	Antirestriction protein ArdC	316
2918747436	198	76.24	37	120	23	99	3.3e-13	43.4	COG1605	Chorismate mutase	101
2918747437	250	99.17	10	250	2	241	1.7e-105	346.1	COG1126	ABC-type polar amino acid transport system, ATPase component	240
2918747439	226	96.49	2	226	4	223	6.0e-75	246.2	COG4160	ABC-type arginine/histidine transport system, permease component	228
2918747440	223	96.96	2	223	3	225	3.2e-69	227.4	COG4215	ABC-type arginine transport system, permease component	230
2918747441	237	87.28	1	237	28	274	1.4e-59	196.4	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918747443	173	40	2	109	19	70	2.1e-12	42.3	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918747448	651	78.41	78	586	109	580	6.9e-121	399	COG3505	Type IV secretory pathway, VirD4 component, TraG/TraD family ATPase	596
2918747449	382	90.71	39	371	15	297	3.9e-71	233.9	COG0630	Type IV secretory pathway ATPase VirB11/Archaellum biosynthesis ATPase	312
2918747450	445	94.91	11	441	19	391	7.6e-70	230.8	COG2948	Type IV secretory pathway, VirB10 components	360
2918747451	280	88.28	10	278	27	267	2.1e-47	156.3	COG3504	Type IV secretory pathway, VirB9 components	265
2918747452	240	91.21	1	230	15	232	4.4e-53	174.5	COG3736	Type IV secretory pathway, component VirB8	239
2918747453	350	70.77	7	300	61	365	1.4e-21	69.5	COG3704	Type IV secretory pathway, VirB6 components	406
2918747455	835	99.38	1	822	1	795	0.0e+00	691.4	COG3451	Type IV secretory pathway, VirB4 component	796
2918747456	122	94.29	3	109	2	100	4.1e-29	95.7	COG3702	Type IV secretory pathway, VirB3 components	105
2918747457	110	74.07	13	110	23	102	7.6e-09	30.1	COG3838	Type IV secretory pathway, VirB2 components (pilins)	108
2918747459	262	97.73	1	250	2	259	1.3e-41	137.8	COG1192	Cellulose biosynthesis protein BcsQ	259
2918747461	326	31.08	1	117	9	109	4.0e-42	18.5	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
2918747461	326	47.38	164	323	168	321	4.0e-42	121.9	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
2918747462	235	86.25	161	234	11	79	1.8e-22	72.7	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2918747463	220	88.04	1	208	4	187	3.1e-52	171.9	COG3916	N-acyl-L-homoserine lactone synthetase	209
2918747464	274	95.02	1	274	13	298	1.3e-27	91.6	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918747465	723	96.86	1	189	3	187	2.8e-64	210.2	COG0512	Anthranilate/para-aminobenzoate synthase component II	191
2918747465	723	97.43	219	685	6	460	1.8e-130	430.7	COG0147	Anthranilate/para-aminobenzoate synthases component I	462
2918747466	172	97.47	3	160	3	156	5.0e-42	138.2	COG1522	DNA-binding transcriptional regulator, Lrp family	154
2918747467	1200	92.65	741	949	4	192	1.2e-24	81	COG1014	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, gamma subunit	203
2918747467	1200	98.6	25	720	3	637	0.0e+00	523.8	COG4231	TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit	640
2918747468	229	87.26	11	219	22	206	2.2e-56	185.3	COG0684	Regulator of RNase E activity RraA	210
2918747469	329	95.92	9	328	12	317	8.8e-91	298.9	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918747470	384	94.44	1	382	20	393	5.0e-124	408.8	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
2918747471	332	96.68	3	297	2	292	8.0e-52	171.4	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918747473	332	96.71	17	332	4	326	8.5e-43	141.1	COG1275	Tellurite resistance protein TehA and related permeases	329
2918747474	317	96	1	317	9	320	1.4e-88	291.7	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
2918747475	1055	84.8	573	1048	57	441	1.6e-60	199.3	COG0770	UDP-N-acetylmuramyl pentapeptide synthase	451
2918747478	737	97.67	21	731	15	684	3.6e-122	403.3	COG1289	Uncharacterized membrane protein YccC	674
2918747479	180	87.22	14	154	15	130	6.9e-24	78.9	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918747480	326	97.49	6	326	8	318	8.8e-61	200.3	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918747481	402	48.83	1	209	5	191	6.2e-16	36.5	COG0477	MFS family permease	338
2918747481	402	48.83	198	395	8	194	6.2e-16	20.9	COG0477	MFS family permease	338
2918747482	452	15.99	314	450	387	461	3.8e-44	9.1	COG0277	FAD/FMN-containing dehydrogenase	459
2918747482	452	40.51	16	218	20	209	3.8e-44	137.6	COG0277	FAD/FMN-containing dehydrogenase	459
2918747483	301	97.01	5	301	2	293	1.7e-55	183.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918747484	43	31.67	1	42	79	116	4.8e-07	24.2	COG1733	DNA-binding transcriptional regulator, HxlR family	120
2918747486	324	98.75	4	323	4	318	2.4e-93	307.4	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918747487	384	93.27	1	376	6	379	3.5e-120	396.1	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2918747488	297	97.34	5	297	2	294	1.3e-64	213.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918747489	182	68.06	12	180	39	168	6.0e-48	157.6	COG4420	Uncharacterized membrane protein	191
2918747490	249	61.63	5	81	17	69	4.2e-04	15.1	COG3831	WGR domain, predicted DNA-binding domain in MolR	85
2918747492	199	98.12	1	199	3	211	1.1e-48	160.7	COG0655	Multimeric flavodoxin WrbA	207
2918747493	303	97.67	5	302	3	296	6.5e-49	161.8	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918747495	318	99.4	2	318	3	331	3.0e-71	235.1	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2918747496	257	98.88	4	255	3	267	3.6e-66	218.1	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918747497	144	87.6	9	142	9	121	1.2e-09	32.2	COG4922	Predicted SnoaL-like aldol condensation-catalyzing enzyme	129
2918747498	258	99.25	4	253	2	267	2.4e-75	248.1	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918747499	147	87.5	8	138	13	138	4.3e-30	99.4	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
2918747500	321	81.82	193	320	14	121	9.9e-28	90.7	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918747501	278	92.16	1	257	4	250	3.8e-61	201.6	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918747502	301	78.03	180	301	23	125	5.4e-33	107.9	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918747503	248	98.78	1	248	4	246	1.6e-90	297.8	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
2918747504	237	93.78	7	237	10	235	5.6e-54	177.7	COG2186	DNA-binding transcriptional regulator, FadR family	241
2918747505	396	99.48	34	394	2	383	2.2e-71	235.5	COG4134	ABC-type uncharacterized transport system YnjBCD, periplasmic component	384
2918747506	366	98	5	359	3	345	2.9e-113	373.3	COG3839	ABC-type sugar transport system, ATPase component	338
2918747507	287	90.97	2	280	16	277	2.0e-47	156.5	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
2918747508	280	93.26	1	272	11	259	9.0e-58	190.1	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
2918747509	400	95.44	1	396	12	367	5.9e-93	306.2	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
2918747510	326	95.21	4	308	14	311	2.6e-46	152.9	COG2017	Galactose mutarotase or related enzyme	308
2918747511	301	96.66	9	301	4	292	4.1e-58	191.1	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
2918747512	321	98.43	2	320	4	317	9.6e-91	298.7	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918747513	301	98.01	6	301	3	297	8.8e-68	223.9	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918747514	296	95.29	1	282	2	264	2.6e-31	103.6	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
2918747515	176	56.71	8	159	50	142	1.5e-07	24.6	COG2010	Cytochrome c, mono- and diheme variants	150
2918747516	215	91.16	21	213	14	209	2.5e-39	129.9	COG0625	Glutathione S-transferase	211
2918747517	361	95.16	26	356	17	370	9.5e-48	155.2	COG2021	Homoserine acetyltransferase	368
2918747518	270	43.93	26	203	51	155	1.9e-26	87	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
2918747519	276	52.72	46	234	41	166	1.0e-24	81.1	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
2918747521	192	50	15	182	78	170	1.4e-08	28.2	COG3247	Uncharacterized membrane protein HdeD, DUF308 family	185
2918747522	489	15.91	109	175	219	274	5.5e-31	4	COG2206	HD-GYP domain, c-di-GMP phosphodiesterase class II (or its inactivated variant)	344
2918747522	489	48.58	176	418	147	317	5.5e-31	95.2	COG2206	HD-GYP domain, c-di-GMP phosphodiesterase class II (or its inactivated variant)	344
2918747523	69	27.65	2	67	103	149	7.5e-08	27.2	COG0262	Dihydrofolate reductase	167
2918747525	249	94.19	1	241	15	306	4.4e-86	283.5	COG0024	Methionine aminopeptidase	255
2918747526	382	8.08	76	131	39	70	2.2e-53	2.4	COG0372	Citrate synthase	390
2918747526	382	52.27	137	382	182	388	2.2e-53	172	COG0372	Citrate synthase	390
2918747527	317	88.07	1	316	35	322	7.4e-75	246.4	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
2918747528	323	98.12	3	321	3	315	2.0e-90	297.7	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918747529	325	98.12	3	324	6	318	1.2e-83	275.4	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918747530	131	72.26	1	115	13	111	5.8e-09	30.4	COG4319	Ketosteroid isomerase homolog	137
2918747531	290	94.06	3	285	2	270	5.7e-71	233.6	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
2918747533	135	95.21	3	130	2	140	1.3e-13	46.9	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2918747534	164	33.54	2	121	212	320	1.3e-27	91	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
2918747535	159	99.34	1	153	2	151	3.2e-63	207	COG3865	Glyoxalase superfamily enzyme, possibly 3-demethylubiquinone-9 3-methyltransferase	151
2918747536	225	97.21	1	211	1	209	1.2e-34	114.6	COG0625	Glutathione S-transferase	211
2918747537	143	97.95	3	131	2	144	1.6e-14	50	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2918747538	288	98.64	3	284	3	293	3.7e-30	100.3	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918747539	174	91.76	4	165	2	157	6.3e-21	69.1	COG0645	Predicted kinase	170
2918747540	137	82.35	1	136	1	126	1.6e-09	31.9	COG1246	N-acetylglutamate synthase or related acetyltransferase, GNAT family	153
2918747542	249	93.75	1	241	7	246	3.5e-75	247.1	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
2918747543	148	96.82	1	144	6	157	1.0e-24	81.8	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
2918747545	286	82.58	157	282	17	125	1.0e-22	74.5	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918747546	234	97.38	3	229	4	226	9.0e-58	189.7	COG3382	B3/B4 domain (DNA/RNA-binding domain of Phe-tRNA-synthetase)	229
2918747547	260	98.78	3	252	3	245	4.1e-65	213.8	COG1414	DNA-binding transcriptional regulator, IclR family	246
2918747548	335	94.28	1	330	7	319	2.4e-108	356.8	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
2918747549	149	98.63	1	146	1	144	2.6e-52	170.9	COG0757	3-dehydroquinate dehydratase	146
2918747550	337	97.59	1	336	3	326	1.1e-108	358.1	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
2918747551	194	95.11	10	194	2	176	3.7e-47	155.1	COG0431	NAD(P)H-dependent FMN reductase	184
2918747552	232	93.1	6	232	15	230	1.0e-46	153.7	COG1802	DNA-binding transcriptional regulator, GntR family	230
2918747553	183	41.39	10	157	16	128	2.2e-13	44.6	COG2514	Catechol-2,3-dioxygenase	265
2918747554	287	87.18	15	287	35	272	3.0e-80	264.3	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
2918747555	323	97.49	3	322	6	316	9.7e-86	282.3	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918747557	339	99.4	5	333	2	330	1.2e-74	246.3	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2918747558	188	81.62	10	184	20	170	6.0e-40	131.4	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
2918747559	371	92.54	13	363	21	293	2.9e-27	90.6	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918747560	304	96.35	2	296	1	290	1.6e-57	190.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918747562	301	97.67	2	297	3	296	1.4e-59	196.9	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918747563	486	99.13	15	486	2	457	4.4e-91	300.7	COG1538	Outer membrane protein TolC	457
2918747564	320	94.6	4	319	9	341	1.1e-85	281.7	COG1566	Multidrug resistance efflux pump	352
2918747566	672	97.81	3	672	5	675	1.3e-79	262.8	COG1289	Uncharacterized membrane protein YccC	674
2918747568	323	57.25	44	156	41	115	1.3e-03	12.8	COG1917	Cupin domain protein related to quercetin dioxygenase	131
2918747568	323	70.45	186	322	33	125	2.1e-21	70.4	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918747569	259	98.88	7	254	2	266	3.8e-63	208.1	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918747570	381	98.94	2	378	2	375	5.1e-102	336.3	COG2828	2-Methylaconitate cis-trans-isomerase PrpF (2-methyl citrate pathway)	378
2918747571	119	49.65	31	117	53	122	1.1e-07	26.1	COG1545	Uncharacterized OB-fold protein, contains Zn-ribbon domain	140
2918747572	378	97.97	1	374	1	386	1.2e-68	226.5	COG0183	Acetyl-CoA acetyltransferase	392
2918747573	259	99.25	10	255	2	267	3.5e-71	234.5	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918747574	388	96.01	1	385	13	397	4.2e-129	425.5	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2918747575	258	97.74	1	255	7	265	3.2e-85	280.4	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918747576	327	97.18	6	326	8	317	1.2e-67	222.8	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918747577	298	97.41	7	298	2	302	3.3e-54	178.8	COG1893	Ketopantoate reductase	307
2918747578	279	92.91	3	274	8	269	3.3e-60	198	COG1737	DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains	281
2918747579	135	43.85	1	135	163	294	2.2e-06	21.8	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918747580	290	95.68	8	290	6	293	1.3e-59	197	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918747581	413	51.96	215	410	6	204	1.4e-17	27.3	COG0477	MFS family permease	338
2918747581	413	52.48	11	220	8	208	1.4e-17	37.9	COG0477	MFS family permease	338
2918747582	240	98.31	5	237	4	236	5.1e-78	256.1	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2918747583	254	98.43	1	246	5	254	5.4e-82	269.5	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2918747584	337	95.05	18	324	13	319	7.9e-62	203.7	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918747585	289	97.01	2	289	5	296	1.6e-72	239.2	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2918747586	392	96.45	8	375	6	358	4.5e-43	142.1	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918747587	213	92.72	24	207	8	198	5.8e-33	108.9	COG1335	Nicotinamidase-related amidase	205
2918747589	331	94.41	2	323	16	302	5.5e-53	174.9	COG2159	Predicted metal-dependent hydrolase, TIM-barrel fold	293
2918747590	171	96.34	15	171	4	161	1.4e-17	58.9	COG5517	3-phenylpropionate/cinnamic acid dioxygenase, small subunit	164
2918747591	436	92.55	27	422	4	351	6.7e-60	197.7	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
2918747592	417	90.47	6	387	1	389	4.9e-57	188.7	COG0446	NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase	415
2918747593	105	95.33	1	101	3	104	2.4e-29	95.9	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
2918747595	793	99.73	11	784	2	744	0.0e+00	542.9	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
2918747596	283	97.55	1	274	1	279	3.5e-50	165.8	COG1319	CO or xanthine dehydrogenase, FAD-binding subunit	284
2918747597	405	97.26	223	370	4	145	9.6e-20	65.2	COG3427	Carbon monoxide dehydrogenase subunit G	146
2918747597	405	97.44	2	155	3	154	6.5e-56	182.4	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
2918747598	268	96.95	8	265	7	292	3.0e-29	97	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918747599	175	91.73	39	169	6	127	1.3e-20	68.3	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918747600	175	34.09	10	175	7	142	1.5e-27	91.4	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918747601	352	62.32	1	350	8	361	3.0e-58	192.1	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2918747602	615	92.51	71	609	4	460	7.0e-96	316.5	COG2272	Carboxylesterase type B	491
2918747603	358	81.06	209	357	20	126	2.5e-21	69.8	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918747604	494	98.59	8	494	8	497	0.0e+00	591.8	COG0397	Uncharacterized conserved protein YdiU, UPF0061 family	488
2918747605	136	83.69	5	136	12	129	6.1e-54	176.1	COG0229	Peptide methionine sulfoxide reductase MsrB	140
2918747606	179	98.33	1	178	1	177	2.1e-60	198.6	COG2917	Intracellular septation protein A	180
2918747607	93	84.44	1	93	6	81	1.4e-27	90.6	COG0271	Stress-induced morphogen (activity unknown)	90
2918747608	261	94.46	5	261	2	308	1.7e-43	143.1	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
2918747609	1340	97.75	176	1014	3	742	0.0e+00	875	COG0046	Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain	743
2918747609	1340	99.18	1087	1340	2	243	3.7e-81	266.1	COG0047	Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain	231
2918747610	274	99.03	1	261	1	307	4.3e-87	286.5	COG0024	Methionine aminopeptidase	255
2918747611	868	95.85	5	868	32	862	0.0e+00	945.2	COG2844	UTP:GlnB (protein PII) uridylyltransferase	867
2918747612	551	99.24	27	551	2	521	0.0e+00	680.3	COG0033	Phosphoglucomutase	524
2918747614	352	90.35	94	351	21	226	6.3e-61	200	COG0765	ABC-type amino acid transport system, permease component	222
2918747615	333	38.29	175	331	243	394	1.2e-95	189.3	COG4597	ABC-type amino acid transport system, permease component	397
2918747615	333	41.06	2	179	25	187	1.2e-95	130.6	COG4597	ABC-type amino acid transport system, permease component	397
2918747616	344	87.28	2	266	3	249	1.2e-41	137.2	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918747617	131	87.5	1	131	12	137	4.2e-22	73.8	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
2918747618	179	91.12	1	166	1	154	1.0e-48	159.6	COG0242	Peptide deformylase	168
2918747620	694	99.55	1	689	3	673	0.0e+00	897.9	COG0272	NAD-dependent DNA ligase	667
2918747622	1171	99.83	1	1168	2	1167	0.0e+00	791.6	COG1196	Chromosome segregation ATPase	1163
2918747624	109	47.69	5	103	4	65	2.9e-05	20	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918747627	167	88.44	8	167	18	170	5.4e-34	112.2	COG1495	Disulfide bond formation protein DsbB	170
2918747628	365	99.71	1	360	1	349	0.0e+00	470.1	COG1118	ABC-type sulfate/molybdate transport systems, ATPase component	345
2918747629	300	95.82	4	288	9	283	0.0e+00	472.6	COG4208	ABC-type sulfate transport system, permease component	287
2918747630	295	97.81	21	294	6	273	6.2e-112	367.5	COG0555	ABC-type sulfate transport system, permease component	274
2918747631	338	94.56	2	338	18	347	0.0e+00	442.7	COG1613	ABC-type sulfate transport system, periplasmic component	348
2918747632	191	97.79	1	177	2	178	1.1e-61	202.3	COG3545	Predicted esterase of the alpha/beta hydrolase fold	181
2918747633	213	95.31	2	193	3	185	4.7e-69	226.3	COG0450	Alkyl hydroperoxide reductase subunit AhpC (peroxiredoxin)	194
2918747634	304	98.01	2	301	2	296	1.1e-66	220.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918747635	215	98.02	1	202	3	200	1.9e-64	211.4	COG1182	FMN-dependent NADH-azoreductase	202
2918747636	185	90.76	4	184	2	168	2.1e-48	159.2	COG0431	NAD(P)H-dependent FMN reductase	184
2918747637	311	99.03	1	310	1	306	3.6e-68	224.7	COG1893	Ketopantoate reductase	307
2918747639	455	79.85	18	373	3	327	2.5e-42	139.8	COG0644	Dehydrogenase (flavoprotein)	396
2918747640	304	80.61	114	302	7	164	3.9e-49	161.1	COG1045	Serine acetyltransferase	194
2918747641	71	97.1	4	71	2	68	4.3e-31	101.7	COG3585	Molybdopterin-binding protein	69
2918747642	428	99.3	1	427	3	426	0.0e+00	654.8	COG2873	O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent	426
2918747643	276	97.21	16	256	4	247	2.7e-87	286.9	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2918747644	324	94.03	1	319	5	319	3.1e-60	198.8	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918747645	284	95.74	23	279	11	257	6.4e-89	292.3	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2918747646	389	99.42	6	363	1	341	5.5e-87	286.7	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2918747648	318	93.13	5	314	5	316	3.2e-54	178.9	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918747650	194	91.3	1	176	2	169	2.7e-38	126.1	COG0431	NAD(P)H-dependent FMN reductase	184
2918747651	346	94.84	3	346	17	347	0.0e+00	525.4	COG1613	ABC-type sulfate transport system, periplasmic component	348
2918747652	90	98.89	1	90	1	89	1.7e-42	138.1	COG2924	Fe-S cluster biosynthesis and repair protein YggX	90
2918747653	619	91.34	2	235	12	243	5.1e-60	197.1	COG4121	tRNA U34 5-methylaminomethyl-2-thiouridine-forming methyltransferase MnmC	252
2918747653	619	94.07	246	614	8	372	2.2e-39	129.3	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918747654	299	88.17	1	295	10	307	8.6e-35	114.2	COG1305	Transglutaminase-like enzyme, putative cysteine protease	319
2918747656	233	90.8	41	213	4	161	1.4e-61	202.1	COG0225	Peptide methionine sulfoxide reductase MsrA	174
2918747657	343	98.49	2	335	5	331	4.0e-120	395.2	COG3588	Fructose-bisphosphate aldolase class 1	332
2918747658	390	95.36	1	379	4	373	4.0e-66	218.4	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918747659	297	97.34	6	297	1	293	1.3e-61	203.7	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918747660	342	97.81	1	327	2	314	3.2e-104	342.9	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
2918747663	152	73.46	4	137	40	158	2.3e-12	42	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2918747664	152	93.94	13	130	2	125	2.2e-13	45.2	COG0789	DNA-binding transcriptional regulator, MerR family	124
2918747665	321	95.04	9	286	4	271	1.3e-66	219	COG1737	DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains	281
2918747666	318	99.03	3	317	3	307	3.9e-107	352.8	COG1446	Isoaspartyl peptidase or L-asparaginase, Ntn-hydrolase superfamily	307
2918747667	625	99.09	7	578	5	551	0.0e+00	743.8	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
2918747668	517	96.89	1	514	5	564	1.6e-115	381.7	COG0747	ABC-type transport system, periplasmic component	556
2918747669	306	99.37	1	306	1	316	7.7e-118	388.2	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2918747670	306	95.3	19	306	13	296	4.3e-103	338.9	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2918747671	358	96.26	7	344	9	343	4.1e-110	362.4	COG3191	L-aminopeptidase/D-esterase	348
2918747672	273	98.91	1	273	1	271	1.3e-95	314.3	COG2362	D-aminopeptidase	274
2918747673	592	99.61	1	583	1	512	0.0e+00	495.8	COG0155	Sulfite reductase, beta subunit (hemoprotein)	510
2918747674	131	61.08	7	129	58	159	1.7e-32	107	COG3749	Uncharacterized conserved protein, DUF934 family	167
2918747675	216	70.52	6	208	16	204	7.9e-30	98.5	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
2918747676	317	94.78	11	317	15	268	1.1e-62	206.3	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
2918747677	445	94.7	16	445	5	415	0.0e+00	456.6	COG2895	Sulfate adenylyltransferase subunit 1, EFTu-like GTPase family	431
2918747678	109	93.15	1	65	5	72	1.0e-18	61.7	COG1146	NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit	68
2918747679	344	95.77	9	321	4	297	4.1e-50	165	COG0492	Thioredoxin reductase	305
2918747680	436	98.38	18	428	3	427	2.4e-111	365.8	COG0001	Glutamate-1-semialdehyde aminotransferase	432
2918747682	446	77.01	2	425	13	357	1.0e-40	133.7	COG1457	Purine-cytosine permease or related protein	442
2918747683	287	97.34	14	277	4	259	4.7e-99	325.2	COG0351	Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase	263
2918747684	363	93.81	6	357	7	370	1.4e-44	147.1	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918747685	67	100	1	67	1	68	3.5e-19	63.4	COG2104	Sulfur carrier protein ThiS (thiamine biosynthesis)	68
2918747686	274	98.47	7	271	4	261	1.1e-109	360.3	COG2022	Thiamin biosynthesis thiazole synthase ThiGH, ThiG subunit	262
2918747687	310	91.94	96	310	14	207	3.2e-58	190.8	COG0352	Thiamine monophosphate synthase	211
2918747688	718	97.99	5	717	15	793	6.4e-58	191.6	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2918747695	491	25.48	390	491	264	356	7.9e-121	35.7	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
2918747695	491	96.99	9	395	7	360	7.9e-121	367.5	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
2918747696	442	90.61	9	442	31	387	4.5e-62	205.4	COG0642	Signal transduction histidine kinase	336
2918747697	219	98.28	1	219	1	228	7.3e-74	242.6	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918747698	256	97.97	10	256	2	242	8.4e-56	183.3	COG1414	DNA-binding transcriptional regulator, IclR family	246
2918747699	393	99.24	1	388	2	391	2.8e-76	252	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2918747700	132	68.49	3	106	5	104	1.5e-03	8.6	COG3427	Carbon monoxide dehydrogenase subunit G	146
2918747701	303	80.3	146	283	20	125	3.3e-28	92.4	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918747702	776	99.19	8	774	6	744	0.0e+00	636.6	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
2918747703	251	89.59	12	237	12	209	6.1e-72	235.4	COG2360	Leu/Phe-tRNA-protein transferase	221
2918747704	249	94.86	3	249	6	245	9.8e-87	285.3	COG2935	Arginyl-tRNA--protein-N-Asp/Glu arginylyltransferase	253
2918747705	281	100	15	256	1	246	2.6e-73	240.6	COG1414	DNA-binding transcriptional regulator, IclR family	246
2918747706	380	63.87	4	379	38	288	4.2e-71	233.5	COG1686	D-alanyl-D-alanine carboxypeptidase	389
2918747707	512	99.52	3	416	2	412	0.0e+00	498.7	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
2918747708	567	99.27	29	461	1	410	2.7e-120	396.5	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
2918747709	274	97.47	13	257	4	234	3.2e-73	240.8	COG1183	Phosphatidylserine synthase	234
2918747710	338	99.11	1	336	3	337	0.0e+00	538.6	COG0059	Ketol-acid reductoisomerase	338
2918747712	163	97.53	1	161	3	160	8.6e-67	218.6	COG0440	Acetolactate synthase, small subunit	163
2918747713	594	99.28	24	591	3	553	0.0e+00	749	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
2918747714	188	90.32	2	188	14	181	5.4e-33	108.8	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918747717	153	73.3	1	152	25	153	7.4e-13	43.1	COG1714	Uncharacterized membrane protein YckC, RDD family	172
2918747718	135	97.56	14	135	2	121	1.1e-41	136.1	COG0818	Diacylglycerol kinase	123
2918747719	196	86.34	2	190	17	193	7.3e-60	196.5	COG1611	Predicted Rossmann fold nucleotide-binding protein	205
2918747720	112	100	1	112	1	112	1.6e-48	158.5	COG0347	Nitrogen regulatory protein PII	112
2918747721	564	89.93	1	281	2	251	2.7e-55	181.7	COG0388	Predicted amidohydrolase	274
2918747721	564	96.35	270	547	5	268	3.3e-81	266.8	COG0171	NH3-dependent NAD+ synthetase	268
2918747722	393	97.67	1	393	7	384	0.0e+00	472.4	COG3146	Predicted N-acyltransferase	387
2918747723	250	97.61	1	250	1	245	3.0e-67	221.9	COG4700	Uncharacterized protein	251
2918747724	175	100	1	175	1	172	4.7e-66	216.4	COG0221	Inorganic pyrophosphatase	171
2918747725	842	78.89	677	842	41	197	7.4e-16	52.9	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
2918747725	842	99.15	2	687	6	702	0.0e+00	1000.5	COG3808	Na+ or H+-translocating membrane pyrophosphatase	703
2918747726	122	72.06	1	121	31	128	1.5e-05	19.8	COG3631	Ketosteroid isomerase-related protein	133
2918747727	209	78.95	8	208	16	180	3.9e-18	61.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918747728	278	93.21	2	268	15	275	2.9e-69	228	COG3687	Predicted metal-dependent hydrolase	280
2918747733	647	94.48	5	374	2	309	3.8e-39	127.6	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
2918747734	318	73.49	4	317	44	298	8.0e-12	39.2	COG3239	Fatty acid desaturase	343
2918747735	255	84.7	2	254	21	258	1.1e-36	121.3	COG3000	Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily	271
2918747736	524	84.74	33	520	67	477	2.6e-75	248.3	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
2918747737	184	97.45	23	178	3	155	1.3e-35	116.9	COG1225	Peroxiredoxin	157
2918747738	477	98.96	2	477	3	476	0.0e+00	515	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918747739	383	99.69	33	383	2	325	6.2e-109	358.4	COG2896	Molybdenum cofactor biosynthesis enzyme MoaA	322
2918747740	216	97.94	10	216	3	192	1.8e-54	178.8	COG0746	Molybdopterin-guanine dinucleotide biosynthesis protein A	192
2918747741	438	96.31	15	438	13	404	0.0e+00	431.5	COG0303	Molybdopterin biosynthesis enzyme	404
2918747742	149	93.59	1	148	3	148	2.3e-58	191.2	COG0328	Ribonuclease HI	154
2918747743	258	43.73	11	242	111	232	8.2e-07	24.2	COG0500	SAM-dependent methyltransferase	257
2918747744	244	87.31	1	211	32	258	1.7e-47	156.7	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2918747745	536	80.95	362	469	2	120	2.0e-03	11.6	COG1388	LysM repeat	124
2918747746	277	97.29	1	272	6	256	1.9e-71	235	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2918747747	298	26.29	213	289	182	247	1.9e-85	56	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2918747747	298	66.14	5	192	16	181	1.9e-85	223.1	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2918747748	337	90.75	1	334	12	315	7.1e-52	171.3	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918747749	130	96.8	6	130	1	121	6.4e-36	117.7	COG3686	Uncharacterized conserved protein, MAPEG superfamily	125
2918747750	196	97.47	1	196	4	196	5.0e-77	252.4	COG0353	Recombinational DNA repair protein RecR	198
2918747751	110	100	1	107	1	105	3.3e-42	137.6	COG0718	Conserved DNA-binding protein YbaB (function unknown)	105
2918747752	619	72.31	1	590	1	423	0.0e+00	489	COG2812	DNA polymerase III, gamma/tau subunits	515
2918747754	199	87.14	12	199	23	205	4.7e-17	56.7	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
2918747757	412	98.77	2	410	4	405	1.4e-122	404	COG2081	Predicted flavoprotein YhiN	408
2918747758	1087	98.18	13	1087	8	1138	0.0e+00	422.7	COG1074	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)	1139
2918747759	864	93.31	595	858	2	252	1.2e-26	87.1	COG2887	RecB family exonuclease	269
2918747760	110	34.75	1	110	25	130	1.4e-33	111.5	COG3118	Negative regulator of GroEL, contains thioredoxin-like and TPR-like domains	304
2918747761	411	96.21	1	410	15	420	0.0e+00	674.9	COG1158	Transcription termination factor Rho	422
2918747762	357	99.15	3	354	2	349	3.5e-76	251.4	COG0673	Predicted dehydrogenase	342
2918747763	89	93.33	2	88	2	71	1.2e-26	87.3	COG0254	Ribosomal protein L31	75
2918747764	575	30.53	12	224	8	174	7.3e-05	11.4	COG1807	4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferase of PMT family	535
2918747764	575	35.1	291	536	271	462	7.3e-05	15.8	COG1807	4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferase of PMT family	535
2918747765	447	92.39	4	446	27	451	7.0e-81	266.4	COG0534	Na+-driven multidrug efflux pump	455
2918747766	431	85.53	3	427	56	392	6.4e-66	216.3	COG0642	Signal transduction histidine kinase	336
2918747767	230	98.71	4	228	2	230	8.6e-86	281.6	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918747768	233	94.29	1	233	7	237	4.4e-55	181.4	COG0704	Phosphate uptake regulator	240
2918747769	259	98.43	6	259	5	254	4.9e-126	413.9	COG1117	ABC-type phosphate transport system, ATPase component	253
2918747770	294	97.28	13	294	4	289	1.7e-98	323.8	COG0581	ABC-type phosphate transport system, permease component	292
2918747771	359	94.27	40	355	17	312	4.8e-109	358.6	COG0573	ABC-type phosphate transport system, permease component	310
2918747772	345	95.69	1	324	14	324	8.7e-93	305.6	COG0226	ABC-type phosphate transport system, periplasmic component	318
2918747773	506	99.39	3	496	3	494	1.6e-121	401.1	COG0248	Exopolyphosphatase/pppGpp-phosphohydrolase	492
2918747776	153	93.87	1	153	2	154	2.4e-31	103.3	COG2062	Phosphohistidine phosphatase SixA	163
2918747777	712	97.42	9	700	11	691	0.0e+00	782.5	COG0855	Polyphosphate kinase	696
2918747778	286	86.69	17	286	33	286	4.4e-58	191.5	COG3176	Putative hemolysin	292
2918747779	559	98.7	227	557	3	305	2.0e-71	235	COG0492	Thioredoxin reductase	305
2918747780	234	96.28	5	213	4	210	2.0e-61	202.1	COG0625	Glutathione S-transferase	211
2918747784	67	6.24	2	48	77	105	1.5e-04	15.2	COG2211	Na+/melibiose symporter or related transporter	467
2918747786	312	15.67	74	162	281	335	1.6e-17	9.5	COG3435	Gentisate 1,2-dioxygenase	351
2918747786	312	35.61	160	311	52	176	1.6e-17	46.6	COG3435	Gentisate 1,2-dioxygenase	351
2918747787	424	98.33	16	420	4	414	1.1e-46	154.4	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
2918747788	293	98.98	1	272	2	293	4.2e-41	136.1	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918747789	391	92.68	7	382	27	393	7.5e-60	197.5	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
2918747790	277	98.88	3	258	3	267	3.5e-50	165.6	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918747791	247	92.67	16	244	12	226	1.0e-53	176.7	COG1802	DNA-binding transcriptional regulator, GntR family	230
2918747792	279	96.52	1	279	7	283	7.4e-69	227	COG2175	Taurine dioxygenase, alpha-ketoglutarate-dependent	286
2918747793	256	86.61	9	227	4	197	9.8e-49	160.5	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
2918747794	252	94.19	1	252	12	254	5.1e-60	197.7	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2918747795	252	97.29	1	252	6	256	5.8e-67	220.5	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2918747796	284	98.41	19	276	3	249	2.1e-89	293.8	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2918747797	335	96.42	1	333	4	326	1.9e-43	143.6	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918747798	475	98.75	4	473	3	477	1.6e-107	355.1	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
2918747800	381	96.5	12	377	14	371	1.7e-87	288	COG3616	D-serine deaminase, pyridoxal phosphate-dependent	368
2918747802	275	97.74	1	271	7	265	7.6e-63	207	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918747803	619	96.79	1	619	20	622	0.0e+00	665.2	COG3211	Secreted phosphatase, PhoX family	616
2918747804	129	98.29	1	123	2	116	1.1e-27	91.5	COG3189	Uncharacterized conserved protein YeaO, DUF488 family	117
2918747805	202	93.95	1	201	1	202	3.8e-26	86.8	COG0625	Glutathione S-transferase	211
2918747806	300	98.88	5	267	3	267	4.6e-47	155.4	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918747807	292	78.3	1	291	6	319	2.6e-47	155.7	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2918747810	217	87.23	119	211	7	88	1.4e-27	89.9	COG3326	Uncharacterized membrane protein YsdA, DUF1294 family	94
2918747810	217	95.52	2	68	3	66	2.3e-10	34.6	COG1278	Cold shock protein, CspA family	67
2918747811	801	99.8	53	719	1	497	0.0e+00	532.4	COG1032	Radical SAM superfamily enzyme YgiQ, UPF0313 family	490
2918747812	320	75.93	157	306	35	157	2.5e-10	35.4	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2918747812	320	98.5	19	152	1	131	1.3e-24	81	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918747813	501	98.21	1	501	5	499	0.0e+00	468.2	COG3333	TctA family transporter	504
2918747815	335	97.49	12	335	9	319	5.3e-72	237.2	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918747816	260	99.63	1	259	1	267	2.2e-66	218.8	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918747817	403	97.49	20	376	6	316	4.1e-60	198.4	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
2918747819	183	97.8	1	181	5	182	1.4e-76	251.1	COG3803	Uncharacterized conserved protein, DUF924 family	182
2918747820	301	93.4	1	293	13	295	1.4e-62	206.2	COG1295	Uncharacterized membrane protein, BrkB/YihY/UPF0761 family (not an RNase)	303
2918747821	196	86.8	16	195	8	178	6.7e-33	108.5	COG2059	Chromate transport protein ChrA	195
2918747822	202	88.83	7	202	4	178	1.4e-24	80.8	COG2059	Chromate transport protein ChrA	195
2918747823	321	97.81	2	321	3	315	2.7e-102	336.6	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
2918747824	173	95.27	1	168	6	166	8.1e-58	189.6	COG1247	L-amino acid N-acyltransferase YncA	169
2918747825	195	84.62	17	164	2	111	2.3e-17	58.5	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918747827	248	90.87	1	248	23	261	3.6e-78	257.2	COG0566	tRNA G18 (ribose-2'-O)-methylase SpoU	260
2918747829	240	97.81	4	229	3	225	1.2e-95	313.9	COG4181	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component	228
2918747830	210	94.12	13	210	10	217	3.0e-34	113.5	COG2755	Lysophospholipase L1 or related esterase	216
2918747832	397	97.98	1	397	7	395	4.0e-100	330	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
2918747833	287	80.3	131	284	21	126	9.3e-16	52.2	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918747834	150	96.35	5	133	2	133	2.1e-35	116.3	COG2764	Uncharacterized conserved protein PhnB, glyoxalase superfamily	136
2918747835	179	79.37	7	171	12	161	9.3e-08	24.3	COG3945	Hemerythrin-like domain	189
2918747836	174	73.96	5	164	3	144	6.4e-34	112	COG2236	Hypoxanthine phosphoribosyltransferase	192
2918747837	443	99.3	6	441	2	428	0.0e+00	599.3	COG0104	Adenylosuccinate synthase	430
2918747838	386	98.21	2	385	3	386	1.7e-95	314.5	COG3705	ATP phosphoribosyltransferase regulatory subunit HisZ	390
2918747839	62	93.55	2	62	3	60	1.0e-21	71.6	COG3242	Uncharacterized conserved protein YjeT, DUF2065 family	62
2918747840	299	96.01	1	294	9	297	3.1e-65	215	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
2918747841	453	96.35	100	407	8	297	2.6e-64	211.9	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
2918747842	389	85.19	7	386	5	355	0.0e+00	456.3	COG2262	50S ribosomal subunit-associated GTPase HflX	411
2918747843	87	96.1	8	83	2	75	4.9e-37	120.1	COG1923	sRNA-binding regulator protein Hfq	77
2918747844	447	99.33	1	444	3	444	0.0e+00	569.4	COG1160	Predicted GTPases	444
2918747845	374	94.19	4	374	16	388	8.2e-29	94.4	COG1520	Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat	370
2918747846	230	97.12	1	210	4	205	1.2e-50	166.6	COG2976	Putative negative regulator of RcsB-dependent stress response	207
2918747847	440	97.69	2	435	2	423	0.0e+00	432.6	COG0124	Histidyl-tRNA synthetase	429
2918747848	426	98.11	15	423	5	367	0.0e+00	435.6	COG0821	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase IspG/GcpE	361
2918747849	322	98.97	23	289	2	289	2.4e-27	90	COG1426	Cytoskeletal protein RodZ, contains Xre-like HTH and DUF4115 domains	284
2918747850	278	89.2	15	275	27	249	2.3e-63	208.5	COG3063	Tfp pilus assembly protein PilF	250
2918747851	382	99.43	3	355	2	348	0.0e+00	456.7	COG0820	Adenine C2-methylase RlmN of 23S rRNA A2503 and tRNA A37	349
2918747852	141	97.78	2	136	2	133	5.3e-64	208.8	COG0105	Nucleoside diphosphate kinase	135
2918747853	594	97.56	192	434	3	242	1.2e-71	235.2	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
2918747854	280	92.93	1	180	6	176	1.6e-56	185.2	COG1386	Chromosome segregation and condensation protein ScpB	184
2918747855	341	97.6	31	325	4	288	6.1e-81	266.6	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
2918747856	269	96.85	7	268	8	253	1.5e-78	258.2	COG4105	Outer membrane protein assembly factor BamD, BamD/ComL family	254
2918747857	688	35.99	417	685	423	666	1.6e-112	190.5	COG1199	Rad3-related DNA helicase	654
2918747857	688	42.63	13	402	7	295	1.6e-112	179.5	COG1199	Rad3-related DNA helicase	654
2918747858	56	73.13	1	54	15	63	1.2e-13	45.8	COG5481	Uncharacterized protein	67
2918747859	255	88.6	2	255	21	261	2.4e-32	106.9	COG0631	Serine/threonine protein phosphatase PrpC	262
2918747860	223	34.86	25	219	53	189	8.8e-01	3.5	COG2948	Type IV secretory pathway, VirB10 components	360
2918747861	367	96.77	1	360	10	369	0.0e+00	462.4	COG1485	Predicted ATPase	367
2918747862	476	99.78	2	466	2	455	0.0e+00	540.5	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
2918747863	419	99.31	2	418	2	432	0.0e+00	487.4	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
2918747864	958	99.24	11	950	7	922	0.0e+00	1328.7	COG0567	2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes	906
2918747866	637	100	45	620	1	552	0.0e+00	658.3	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
2918747867	200	93.69	3	183	6	198	7.4e-17	49.8	COG1335	Nicotinamidase-related amidase	205
2918747868	255	72.2	5	252	25	237	2.2e-07	25.1	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918747869	377	86.44	18	377	54	410	5.6e-99	326.4	COG2133	Glucose/arabinose dehydrogenase, beta-propeller fold	399
2918747870	194	50.2	8	171	125	249	2.3e-47	156.9	COG0791	Cell wall-associated hydrolase, NlpC family	197
2918747871	608	99.34	122	591	4	455	0.0e+00	522.4	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
2918747872	197	97.19	1	194	4	176	1.4e-37	123.4	COG5405	ATP-dependent protease HslVU (ClpYQ), peptidase subunit	178
2918747873	555	26.96	2	116	2	118	0.0e+00	102	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
2918747873	555	99.54	114	555	2	433	0.0e+00	493	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
2918747874	904	99.44	9	904	5	886	0.0e+00	1387.1	COG2609	Pyruvate dehydrogenase complex, dehydrogenase (E1) component	887
2918747875	846	64.72	424	836	135	389	3.6e-41	136.9	COG0642	Signal transduction histidine kinase	336
2918747876	210	96.53	4	205	4	198	4.1e-79	259.4	COG4566	Two-component response regulator, FixJ family, consists of REC and HTH domains	202
2918747877	283	98.94	4	283	1	281	5.0e-117	384.5	COG0190	5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase	283
2918747878	685	98.83	1	681	8	682	0.0e+00	819.2	COG0339	Zn-dependent oligopeptidase	683
2918747879	206	85	71	142	3	70	1.8e-05	19.2	COG0695	Glutaredoxin	80
2918747880	243	98.68	20	242	3	227	4.6e-80	262.7	COG0120	Ribose 5-phosphate isomerase	227
2918747881	357	92.58	43	356	4	290	3.0e-105	346.2	COG0167	Dihydroorotate dehydrogenase	310
2918747882	240	72.52	10	129	29	123	8.0e-06	19.9	COG5393	Uncharacterized membrane protein YqjE	131
2918747883	98	90.38	1	98	11	104	3.8e-18	60.9	COG4575	Membrane-anchored ribosome-binding protein, inhibits growth in stationary phase, ElaB/YqjD/DUF883 family	104
2918747884	367	86.51	1	366	1	372	7.5e-94	309.2	COG0579	L-2-hydroxyglutarate oxidase LhgO	429
2918747887	235	88.98	1	233	18	243	2.5e-57	189.3	COG0847	DNA polymerase III, epsilon subunit or related 3'-5' exonuclease	243
2918747888	112	86.41	1	104	7	95	1.7e-26	86.7	COG0633	Ferredoxin	102
2918747889	618	99.34	9	604	4	605	0.0e+00	632	COG0443	Molecular chaperone DnaK (HSP70)	579
2918747890	172	90.23	5	168	2	158	4.1e-27	89.9	COG1076	DnaJ-domain-containing proteins 1	174
2918747891	107	98.18	1	107	3	110	1.8e-40	132.1	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
2918747892	139	96.03	1	131	5	149	2.0e-52	171.6	COG0822	NifU homolog involved in Fe-S cluster formation	150
2918747893	406	99.48	7	390	2	385	0.0e+00	527.2	COG1104	Cysteine sulfinate desulfinase/cysteine desulfurase or related enzyme	386
2918747894	178	94.67	1	149	1	142	3.8e-49	161.1	COG1959	DNA-binding transcriptional regulator, IscR family	150
2918747895	705	98.94	30	695	4	659	0.0e+00	1076.6	COG0556	Excinuclease UvrABC helicase subunit UvrB	663
2918747896	398	100	3	398	1	396	0.0e+00	549.5	COG1448	Aspartate/tyrosine/aromatic aminotransferase	396
2918747897	471	99.04	1	425	1	411	0.0e+00	590.4	COG4553	Poly-beta-hydroxyalkanoate depolymerase	415
2918747898	212	73.74	1	168	36	181	3.2e-50	165.3	COG2878	Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit	198
2918747899	212	99.52	1	209	1	207	4.3e-51	167.6	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
2918747900	308	95.68	14	307	10	297	1.6e-38	127.3	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918747901	165	77.85	6	151	6	128	7.2e-29	95.4	COG1522	DNA-binding transcriptional regulator, Lrp family	154
2918747902	163	97.26	12	147	4	145	1.4e-03	14	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2918747903	342	93.49	13	341	12	327	5.8e-126	414.4	COG0502	Biotin synthase or related enzyme	335
2918747904	682	99.85	1	682	1	645	0.0e+00	860.3	COG4770	Acetyl/propionyl-CoA carboxylase, alpha subunit	645
2918747906	514	98.1	1	514	11	526	0.0e+00	733.7	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component	526
2918747907	350	94.74	8	346	15	320	4.3e-110	362.3	COG1703	Putative periplasmic protein kinase ArgK or related GTPase of G3E family	323
2918747908	158	53.09	12	146	72	157	2.6e-08	29.3	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2918747909	720	96.03	570	720	3	147	2.0e-58	189.7	COG2185	Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding)	143
2918747909	720	96.35	16	555	20	547	0.0e+00	805.1	COG1884	Methylmalonyl-CoA mutase, N-terminal domain/subunit	548
2918747910	215	90.09	1	215	10	218	2.3e-54	179	COG1802	DNA-binding transcriptional regulator, GntR family	230
2918747911	261	99.19	12	257	2	245	1.4e-58	192.3	COG1414	DNA-binding transcriptional regulator, IclR family	246
2918747912	334	96.87	14	333	10	318	3.0e-81	267.5	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918747913	292	95.82	1	286	4	278	1.0e-46	154.1	COG2175	Taurine dioxygenase, alpha-ketoglutarate-dependent	286
2918747914	314	89.23	1	313	17	306	2.9e-87	287.5	COG0042	tRNA-dihydrouridine synthase	323
2918747915	279	86.62	10	277	35	280	1.1e-68	226.1	COG3639	ABC-type phosphate/phosphonate transport system, permease component	283
2918747916	279	91.55	4	279	23	282	1.9e-70	231.9	COG3639	ABC-type phosphate/phosphonate transport system, permease component	283
2918747917	272	89.53	2	260	18	248	1.5e-62	205.6	COG3638	ABC-type phosphate/phosphonate transport system, ATPase component	258
2918747918	285	95.68	1	285	10	297	3.0e-79	261.1	COG3221	ABC-type phosphate/phosphonate transport system, periplasmic component	299
2918747919	416	24.32	339	415	252	332	6.7e-37	45.3	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
2918747919	416	56.76	113	342	5	193	6.7e-37	79.8	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
2918747920	330	49.14	24	327	205	405	1.2e-13	46.4	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2918747921	357	93.35	8	348	5	327	5.2e-110	362.1	COG0709	Selenophosphate synthase	346
2918747923	336	97.9	1	336	3	329	1.5e-88	291.9	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
2918747924	357	98.58	6	347	6	353	4.5e-97	319.4	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
2918747925	317	97.86	6	317	6	325	7.2e-88	289.2	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
2918747926	253	99.25	4	250	2	267	1.7e-68	225.6	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918747927	299	99.3	7	294	2	285	4.4e-88	289.8	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
2918747929	304	27.16	3	76	16	78	1.2e-45	45	COG1802	DNA-binding transcriptional regulator, GntR family	230
2918747929	304	90.09	76	300	15	223	1.2e-45	108.2	COG1802	DNA-binding transcriptional regulator, GntR family	230
2918747930	461	97.32	16	457	9	443	0.0e+00	508.5	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
2918747932	541	96.02	22	539	18	572	1.5e-90	299.2	COG0747	ABC-type transport system, periplasmic component	556
2918747933	314	99.37	1	314	1	316	1.3e-106	351.2	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2918747934	270	90.94	1	270	26	296	9.1e-93	305.1	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2918747935	555	98.88	6	537	3	530	0.0e+00	631.2	COG4172	ABC-type microcin C transport system, duplicated ATPase component YejF	534
2918747938	195	30.62	1	181	380	548	2.6e-68	225.3	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
2918747939	166	53.06	2	83	31	82	2.5e-04	15	COG5416	Uncharacterized integral membrane protein	98
2918747940	101	88.18	1	101	7	103	2.1e-30	99.8	COG4654	Cytochrome c551/c552	110
2918747942	564	97.92	2	564	9	574	0.0e+00	713.7	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
2918747943	311	98.01	6	311	1	295	1.3e-62	206.9	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918747944	310	98.67	2	300	2	298	8.3e-75	246.9	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918747945	257	99.25	4	256	2	267	2.2e-48	159.8	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918747946	273	95.14	1	273	6	279	1.5e-94	310.9	COG0682	Prolipoprotein diacylglyceryltransferase	287
2918747947	222	92.67	1	219	13	227	1.7e-56	185.7	COG1802	DNA-binding transcriptional regulator, GntR family	230
2918747949	329	98.12	7	327	4	316	6.3e-87	286.1	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918747950	511	97.18	1	509	8	559	5.7e-117	385.9	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2918747951	567	85.15	1	381	37	380	2.4e-72	238.9	COG1680	CubicO group peptidase, beta-lactamase class C family	390
2918747953	141	94.34	1	141	6	155	1.1e-20	69.6	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2918747954	273	98.07	4	273	3	256	7.4e-53	173.9	COG0730	Uncharacterized membrane protein YfcA	258
2918747955	113	83.81	1	110	1	88	8.5e-17	55.7	COG3027	Cell division protein ZapA, inhibits GTPase activity of FtsZ	105
2918747956	74	63.29	5	65	27	76	1.3e-04	16.8	COG3074	Cell division protein ZapB, interacts with FtsZ	79
2918747958	646	98.53	24	645	9	612	0.0e+00	476.4	COG4206	Outer membrane cobalamin receptor protein	608
2918747959	469	99.12	21	453	2	450	5.1e-128	422.1	COG1797	Cobyrinic acid a,c-diamide synthase	451
2918747960	191	98.29	4	189	3	174	1.5e-49	162.7	COG2087	Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase	175
2918747961	281	87.65	2	281	36	319	5.2e-38	125.7	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
2918747962	336	97.91	3	333	6	333	1.1e-76	252.7	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
2918747963	259	94.19	5	257	2	244	9.9e-66	216.1	COG1120	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	258
2918747964	189	89.9	1	188	20	197	1.4e-65	215.3	COG2109	ATP:corrinoid adenosyltransferase	198
2918747965	313	96.88	2	311	5	314	2.2e-84	277.6	COG1270	Cobalamin biosynthesis protein CobD/CbiB	320
2918747966	341	93.91	4	340	20	358	4.8e-44	144.8	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
2918747967	117	89.84	1	117	7	121	2.8e-30	99.2	COG1380	Putative effector of murein hydrolase LrgA, UPF0299 family	128
2918747968	243	97.39	13	242	5	228	1.0e-76	251.8	COG1346	Putative effector of murein hydrolase	230
2918747969	158	93.01	1	152	6	138	9.4e-24	78.8	COG1764	Organic hydroperoxide reductase OsmC/OhrA	143
2918747970	304	98.34	2	301	3	298	8.3e-74	243.7	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918747971	293	77.04	1	283	46	290	1.0e-53	177.6	COG0657	Acetyl esterase/lipase	312
2918747972	416	96.67	9	394	10	386	4.1e-68	224.7	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918747973	1091	99.9	2	1039	1	1013	0.0e+00	1192.5	COG0841	Multidrug efflux pump subunit AcrB	1009
2918747974	495	99.13	19	482	1	456	1.4e-113	374.7	COG1538	Outer membrane protein TolC	457
2918747975	479	91.56	2	467	2	446	0.0e+00	502.7	COG1492	Cobyric acid synthase	486
2918747976	348	93.43	7	348	14	340	1.3e-85	281.9	COG2038	NaMN:DMB phosphoribosyltransferase	347
2918747977	264	95.58	1	264	7	244	1.1e-53	177.3	COG0368	Cobalamin synthase	246
2918747978	184	76.56	1	183	2	161	1.3e-26	88.2	COG0406	Broad specificity phosphatase PhoE	208
2918747979	294	75	158	292	27	125	1.3e-11	38.7	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918747980	299	93.66	9	293	3	253	1.7e-45	150.3	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918747981	215	97.63	1	210	3	208	3.5e-82	269.2	COG0177	Endonuclease III	211
2918747982	395	83.99	2	395	68	450	1.3e-121	401.2	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
2918747985	355	96.56	5	351	6	342	5.3e-71	233.7	COG2055	Malate/lactate/ureidoglycolate dehydrogenase, LDH2 family	349
2918747986	236	97.64	21	236	5	211	5.6e-72	236.1	COG0560	Phosphoserine phosphatase	212
2918747987	1164	98.68	1	1158	12	1136	0.0e+00	1435	COG1197	Transcription-repair coupling factor (superfamily II helicase)	1139
2918747988	230	95.26	1	228	7	227	6.3e-64	210	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	230
2918747989	164	98.74	7	164	1	157	1.6e-66	217.9	COG0245	2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	159
2918747990	469	81.47	67	461	69	389	7.5e-50	165	COG0642	Signal transduction histidine kinase	336
2918747991	243	98.71	9	241	2	230	4.0e-86	282.7	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918747993	236	98.3	2	235	5	235	9.1e-42	137.6	COG3471	Predicted secreted (periplasmic) protein	235
2918747994	256	99.25	1	255	2	267	5.1e-70	230.7	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918747995	319	95.25	5	319	7	287	4.7e-24	80.2	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918747996	729	97.1	4	729	21	723	0.0e+00	725.7	COG0317	(p)ppGpp synthase/hydrolase, HD superfamily	701
2918747999	177	91.19	2	176	7	182	7.3e-55	179.3	COG5394	Polyhydroxyalkanoate (PHA) synthesis regulator protein, binds DNA and PHA	193
2918748000	468	98.41	14	468	3	436	7.4e-126	415.2	COG0621	tRNA A37 methylthiotransferase MiaB	437
2918748003	130	73.28	1	115	20	104	4.9e-26	85.7	COG3339	Uncharacterized membrane protein YkvA, DUF1232 family	116
2918748005	737	86.78	1	659	93	709	0.0e+00	728.8	COG0557	Exoribonuclease R	706
2918748006	254	79.1	4	238	2	213	1.5e-55	183.3	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918748007	486	90.97	216	486	21	282	1.1e-63	209.4	COG0063	NAD(P)H-hydrate repair enzyme Nnr, NAD(P)H-hydrate dehydratase domain	284
2918748007	486	94.63	11	207	8	201	3.3e-42	137.6	COG0062	NAD(P)H-hydrate repair enzyme Nnr, NAD(P)H-hydrate epimerase domain	203
2918748008	417	96.13	1	417	5	377	1.1e-63	208.6	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2918748009	441	85.86	16	441	63	475	2.1e-99	328.2	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
2918748010	250	93.36	1	250	7	245	3.6e-98	322.3	COG0052	Ribosomal protein S2	252
2918748011	307	99.66	1	302	1	296	1.8e-97	320.6	COG0264	Translation elongation factor EF-Ts	296
2918748012	240	98.74	5	240	3	237	4.2e-94	309.2	COG0528	Uridylate kinase	238
2918748013	189	97.86	4	189	5	187	1.1e-73	241.3	COG0233	Ribosome recycling factor	187
2918748014	247	92.46	1	229	20	252	8.6e-88	288.6	COG0020	Undecaprenyl pyrophosphate synthase	245
2918748015	281	98.18	1	281	1	270	4.0e-55	182.1	COG0575	CDP-diglyceride synthetase	265
2918748016	395	98.19	5	395	2	380	0.0e+00	508.1	COG0743	1-deoxy-D-xylulose 5-phosphate reductoisomerase	385
2918748017	456	99.5	1	456	2	401	2.6e-79	255.9	COG0750	Membrane-associated protease RseP, regulator of RpoE activity	375
2918748018	811	99.22	7	811	7	774	0.0e+00	691.7	COG4775	Outer membrane protein assembly factor BamA	766
2918748019	180	96.47	1	172	7	170	5.6e-38	125.4	COG2825	Periplasmic chaperone for outer membrane proteins, Skp family	170
2918748020	325	98.22	2	322	5	336	8.2e-104	336.7	COG1044	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase	338
2918748021	149	97.3	2	148	2	145	1.7e-55	181.5	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
2918748022	262	98.85	1	262	3	259	2.5e-104	342.7	COG1043	Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase	260
2918748023	382	98.95	6	382	3	378	1.8e-116	383.7	COG0763	Lipid A disaccharide synthetase	381
2918748024	234	95.54	15	207	2	194	4.2e-65	214.2	COG0164	Ribonuclease HII	199
2918748025	264	96.96	10	256	1	255	2.2e-47	156.1	COG0566	tRNA G18 (ribose-2'-O)-methylase SpoU	260
2918748026	389	98.38	10	389	4	368	0.0e+00	514.3	COG0505	Carbamoylphosphate synthase small subunit	368
2918748028	1082	93.9	566	960	1	385	0.0e+00	295.4	COG0458	Carbamoylphosphate synthase large subunit	400
2918748028	1082	100	13	430	1	410	0.0e+00	702.4	COG0458	Carbamoylphosphate synthase large subunit	400
2918748030	158	99.34	6	158	1	151	5.3e-57	186.7	COG0782	Transcription elongation factor, GreA/GreB family	151
2918748033	159	92.78	5	100	2	91	4.8e-27	88.2	COG1534	RNA-binding protein YhbY	97
2918748034	222	99.02	8	220	2	204	8.2e-75	245.6	COG0293	23S rRNA U2552 (ribose-2'-O)-methylase RlmE/FtsJ	205
2918748035	622	98.34	1	592	8	598	0.0e+00	874.7	COG0465	ATP-dependent Zn proteases	596
2918748036	296	96.76	13	289	8	276	1.2e-89	294.8	COG0294	Dihydropteroate synthase	274
2918748037	445	96.65	1	445	11	472	0.0e+00	431.7	COG1109	Phosphomannomutase	464
2918748038	161	40.12	2	151	88	152	5.0e-12	40.1	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2918748039	423	99.5	1	412	1	397	2.2e-97	321.3	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918748040	368	99.08	13	360	2	325	9.1e-91	298.9	COG3173	Predicted  kinase, aminoglycoside phosphotransferase (APT) family	321
2918748041	239	86.7	19	229	28	216	1.3e-29	97.8	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2918748042	259	97.74	1	258	6	264	8.7e-61	200.2	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918748043	506	33.13	382	498	157	265	2.1e-122	54.5	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
2918748043	506	86.32	4	337	5	288	2.1e-122	346.4	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
2918748044	385	97.47	1	385	7	391	1.2e-79	262.3	COG2814	Predicted arabinose efflux permease, MFS family	394
2918748045	335	92.33	2	335	20	320	5.4e-84	276.3	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
2918748047	227	98.52	4	225	3	202	6.0e-64	210	COG1974	SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase)	201
2918748048	329	89.66	1	329	22	342	1.7e-78	258.6	COG0252	L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D	351
2918748049	218	99.46	1	217	1	184	3.8e-70	230.5	COG0563	Adenylate kinase or related kinase	178
2918748050	257	97.98	1	255	2	243	3.1e-98	322.4	COG1212	CMP-2-keto-3-deoxyoctulosonic acid synthetase	247
2918748051	60	95.45	1	59	1	63	1.6e-24	80.3	COG2835	Uncharacterized conserved protein YbaR, Trm112 family	60
2918748052	346	90.18	19	341	4	306	2.7e-84	277.6	COG1663	Tetraacyldisaccharide-1-P 4'-kinase	336
2918748053	146	97.12	4	143	3	137	4.4e-32	105.6	COG0848	Biopolymer transport protein ExbD	137
2918748054	175	56.02	16	174	87	207	3.6e-39	129.6	COG0811	Biopolymer transport protein ExbB/TolQ	216
2918748056	436	97.98	12	430	5	440	9.6e-129	422.5	COG1570	Exonuclease VII, large subunit	440
2918748057	193	96.59	1	193	2	199	5.4e-73	240	COG0605	Superoxide dismutase	204
2918748058	152	85.71	26	150	11	118	8.2e-38	123.6	COG1430	Uncharacterized conserved membrane protein, UPF0127 family	126
2918748060	107	22.25	3	106	309	409	4.1e-01	3.8	COG3846	Type IV secretory pathway, TrbL components	452
2918748061	419	99.75	10	419	1	407	0.0e+00	627	COG0538	Isocitrate dehydrogenase	407
2918748062	81	73.83	1	80	28	106	1.6e-36	119.2	COG2127	ATP-dependent Clp protease adapter protein ClpS	107
2918748063	773	40.99	420	755	468	797	0.0e+00	442.5	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
2918748063	773	49.69	1	427	3	402	0.0e+00	520.7	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
2918748064	481	99.79	49	481	1	484	3.7e-94	310.7	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
2918748065	479	98.32	1	476	8	474	0.0e+00	627.7	COG2925	Exonuclease I	475
2918748066	426	95.28	1	424	13	416	1.4e-84	278.7	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
2918748068	307	96.71	2	306	10	303	1.8e-91	300.8	COG1079	ABC-type uncharacterized transport system, permease component	304
2918748069	354	96.93	2	354	3	349	3.1e-97	320	COG4603	ABC-type uncharacterized transport system, permease component	356
2918748070	531	99.6	3	519	3	501	0.0e+00	575.5	COG3845	ABC-type uncharacterized transport system, ATPase component	501
2918748071	314	97.05	40	313	4	233	4.2e-51	167.9	COG0775	Nucleoside phosphorylase	234
2918748072	334	97.45	2	333	6	349	3.8e-61	201.5	COG1744	Basic membrane lipoprotein Med, periplasmic binding protein (PBP1-ABC) superfamily	345
2918748073	209	100	1	209	1	210	6.1e-90	295.1	COG0035	Uracil phosphoribosyltransferase	210
2918748075	450	77.55	82	430	44	195	1.8e-39	130.2	COG0807	GTP cyclohydrolase II	193
2918748078	193	91.4	18	192	10	179	2.9e-36	119.3	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918748079	213	100	1	213	1	213	1.1e-53	176.9	COG4944	Uncharacterized protein	213
2918748080	504	99.44	16	497	3	536	2.8e-90	298.2	COG0433	Archaeal DNA helicase HerA or a related bacterial ATPase, contains HAS-barrel and ATPase domains	520
2918748081	103	96.3	16	101	3	80	4.7e-12	40.6	COG0236	Acyl carrier protein	80
2918748082	214	90.05	1	196	12	192	1.2e-15	52.4	COG4648	Uncharacterized membrane protein	201
2918748083	568	20.07	318	463	447	560	2.8e-17	25.9	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2918748083	568	46.48	21	320	96	359	2.8e-17	29	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2918748084	332	96.44	20	332	3	300	9.0e-81	266	COG4261	Predicted acyltransferase, LPLAT superfamily	309
2918748086	801	98.1	8	798	10	782	0.0e+00	577.4	COG4258	Predicted exporter	788
2918748087	274	73.13	32	273	61	256	8.3e-40	131.2	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
2918748088	261	48.39	14	258	45	179	6.9e-08	27.8	COG0500	SAM-dependent methyltransferase	257
2918748089	157	83.23	3	156	12	145	6.8e-32	105.1	COG4706	Predicted 3-hydroxylacyl-ACP dehydratase, HotDog domain	161
2918748090	243	99.63	1	243	1	267	1.3e-66	219.6	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918748091	258	30.64	9	249	7	116	3.7e-17	58.2	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
2918748092	267	79.31	21	266	21	227	5.6e-23	76.1	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
2918748093	343	81.62	184	339	24	134	6.9e-09	29.6	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
2918748094	262	95.4	24	255	6	233	3.0e-47	155.2	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
2918748095	241	99.59	1	241	1	242	9.4e-98	321.2	COG0217	Transcriptional and/or translational regulatory protein YebC/TACO1	241
2918748096	432	99.3	1	429	1	426	0.0e+00	585.4	COG0151	Phosphoribosylamine-glycine ligase	428
2918748097	305	98.35	1	305	6	303	0.0e+00	433.1	COG0408	Coproporphyrinogen III oxidase	303
2918748098	209	98.49	6	208	3	198	1.4e-53	176.4	COG1057	Nicotinic acid mononucleotide adenylyltransferase	197
2918748099	221	94.78	9	122	2	110	1.3e-35	115.5	COG0799	Ribosomal silencing factor RsfS, regulates association of 30S and 50S subunits	115
2918748100	155	100	1	154	1	156	7.3e-53	173.6	COG1576	23S rRNA pseudoU1915 N3-methylase RlmH	155
2918748101	201	96.39	4	201	5	191	1.5e-56	185.3	COG0424	Predicted house-cleaning NTP pyrophosphatase, Maf/HAM1 superfamily	193
2918748102	508	98.77	1	508	1	483	0.0e+00	540.8	COG1530	Ribonuclease G or E	487
2918748103	573	95.78	6	560	19	585	0.0e+00	487.5	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
2918748104	408	96.27	1	406	16	428	5.2e-112	369.7	COG0823	Periplasmic component of the Tol biopolymer transport system	425
2918748105	171	61.81	8	171	75	197	1.0e-42	141.3	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
2918748106	249	92.42	1	248	17	260	2.6e-41	135.5	COG1729	Periplasmic TolA-binding protein (function unknown)	262
2918748107	281	95.45	17	280	8	259	1.5e-79	261.3	COG1179	tRNA A37 threonylcarbamoyladenosine dehydratase	263
2918748109	222	61.58	3	222	77	201	2.4e-22	74.3	COG1974	SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase)	201
2918748110	167	85.61	20	157	3	121	1.1e-05	16.9	COG3597	Uncharacterized conserved protein, DUF697 family	139
2918748111	650	98.88	1	543	3	531	0.0e+00	571.9	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
2918748112	293	90.94	3	286	9	269	1.3e-53	176.6	COG2890	Methylase of polypeptide chain release factors	280
2918748113	391	96.17	1	388	15	416	1.5e-102	338.5	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
2918748114	382	95.2	1	372	7	363	1.3e-126	416.7	COG5008	Tfp pilus assembly protein, ATPase PilU	375
2918748115	277	98.9	2	277	2	270	3.0e-96	316.8	COG2171	Tetrahydrodipicolinate N-succinyltransferase	271
2918748116	403	98.23	2	403	4	392	9.2e-92	302.7	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
2918748117	212	98.56	1	209	1	205	1.6e-55	182.1	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
2918748118	448	93.46	302	448	2	144	5.0e-47	152.3	COG1246	N-acetylglutamate synthase or related acetyltransferase, GNAT family	153
2918748118	448	99.62	24	298	1	264	3.9e-64	210.6	COG0548	Acetylglutamate kinase	265
2918748119	662	8.06	2	85	155	183	3.1e-03	4.8	COG0552	Signal recognition particle GTPase	340
2918748119	662	16.67	165	332	50	109	3.1e-03	4.4	COG0552	Signal recognition particle GTPase	340
2918748120	1283	91.5	2	922	48	844	0.0e+00	862.6	COG1643	HrpA-like RNA helicase	845
2918748121	52	28.57	1	50	20	65	1.4e-02	10	COG3402	Uncharacterized membrane protein YdbS, contains bPH2 (bacterial pleckstrin homology) domain	161
2918748122	391	96.46	12	391	9	390	4.0e-104	343.3	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
2918748123	313	98.67	1	300	1	297	1.8e-57	190	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918748124	124	44.62	5	124	3	114	8.3e-32	105.4	COG2138	Sirohydrochlorin ferrochelatase	245
2918748125	369	98.9	1	368	2	362	7.4e-72	237.1	COG0795	Lipopolysaccharide export LptBFGC system, permease protein LptF	364
2918748126	360	93.42	1	333	22	362	2.5e-46	153.1	COG0795	Lipopolysaccharide export LptBFGC system, permease protein LptF	364
2918748127	503	92.2	6	483	38	486	0.0e+00	506.4	COG0260	Leucyl aminopeptidase	485
2918748128	147	96.53	1	145	3	141	2.3e-22	74.3	COG2927	DNA polymerase III, chi subunit	144
2918748130	401	93.99	23	398	9	352	2.5e-78	258.1	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918748131	130	51.66	4	120	4	112	8.4e-12	39.6	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918748134	309	92.36	1	301	9	286	4.6e-74	243.9	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
2918748135	141	97.16	1	141	4	140	2.3e-14	48.6	COG1585	Membrane protein implicated in regulation of membrane protease activity	140
2918748136	767	98.99	140	764	2	588	0.0e+00	709.2	COG1982	Arginine/lysine/ornithine decarboxylase	557
2918748137	283	53.25	4	283	148	409	3.3e-32	104.6	COG1793	ATP-dependent DNA ligase	444
2918748138	260	97.3	1	260	1	252	1.5e-111	366.6	COG0623	Enoyl-[acyl-carrier-protein] reductase (NADH)	259
2918748139	598	94.6	1	598	15	557	4.0e-117	386.9	COG4166	ABC-type oligopeptide transport system, periplasmic component	562
2918748140	344	99.18	1	344	1	361	0.0e+00	544.4	COG4174	ABC-type microcin C transport system, permease component YejB	364
2918748141	347	98.24	5	346	6	340	0.0e+00	488.1	COG4239	ABC-type microcin C transport system, permease component YejE	341
2918748142	543	99.06	4	543	3	531	0.0e+00	706.8	COG4172	ABC-type microcin C transport system, duplicated ATPase component YejF	534
2918748143	399	24.02	298	394	6	97	5.0e-05	13.6	COG0477	MFS family permease	338
2918748143	399	94.52	9	333	8	369	5.0e-05	7.9	COG0477	MFS family permease	338
2918748144	215	75.32	2	142	10	125	5.0e-24	77.6	COG0779	Ribosome maturation factor RimP	153
2918748145	494	38.35	366	492	64	114	2.1e-05	19.1	COG3743	 Predicted 5' DNA nuclease, flap endonuclease-1-like, helix-3-turn-helix (H3TH) domain	133
2918748145	494	95.98	159	373	2	192	9.6e-77	251	COG0195	Transcription antitermination factor NusA, contains S1 and KH domains	190
2918748146	984	99.29	482	984	3	559	0.0e+00	550.7	COG0532	Translation initiation factor IF-2, a GTPase	509
2918748147	123	94.96	1	120	5	117	3.4e-34	112	COG0858	Ribosome-binding factor A	118
2918748148	322	91.29	4	305	4	286	5.0e-95	313	COG0130	tRNA U55 pseudouridine synthase TruB, may also work on U342 of tmRNA	271
2918748149	611	99.5	2	609	3	602	0.0e+00	951.7	COG1217	Predicted membrane GTPase involved in stress response	603
2918748150	309	95.68	4	298	8	295	3.9e-23	76.8	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918748151	131	86.96	1	131	19	138	3.1e-45	148.2	COG4315	Predicted lipoprotein with conserved Yx(FWY)xxD motif (function unknown)	138
2918748152	274	97.28	5	273	7	256	2.2e-56	186	COG5662	Transmembrane transcriptional regulator (anti-sigma factor RsiW)	256
2918748153	171	88.71	1	164	17	181	8.8e-45	147.3	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918748154	126	73.19	5	126	38	138	1.7e-46	152.2	COG4315	Predicted lipoprotein with conserved Yx(FWY)xxD motif (function unknown)	138
2918748155	158	97.39	4	158	3	151	7.2e-64	208.8	COG0691	tmRNA-binding protein	153
2918748156	148	99.32	1	148	1	145	3.8e-51	167.2	COG2867	Ribosome association toxin PasT (RatA) of the RatAB toxin-antitoxin module	146
2918748157	111	91.92	1	98	4	94	1.5e-20	68.1	COG2914	Putative antitoxin component PasI (RatB) of the RatAB toxin-antitoxin module, ubiquitin-RnfH superfamily	99
2918748158	170	26.46	15	167	54	157	1.8e-01	5.9	COG2948	Type IV secretory pathway, VirB10 components	360
2918748159	489	83.49	1	209	13	194	9.3e-109	141.3	COG0516	IMP dehydrogenase/GMP reductase	170
2918748159	489	100	255	478	1	218	9.3e-109	217.5	COG0516	IMP dehydrogenase/GMP reductase	170
2918748160	82	65.48	1	81	1	55	1.1e-15	52.3	COG4118	Antitoxin component of toxin-antitoxin stability system, DNA-binding transcriptional repressor	84
2918748161	144	94.78	2	139	4	130	1.3e-15	52.5	COG4113	Predicted nucleic acid-binding protein, contains PIN domain	134
2918748162	539	98.99	3	206	2	197	6.9e-70	229.3	COG0518	GMP synthase - Glutamine amidotransferase domain	198
2918748162	539	99.68	207	539	2	316	0.0e+00	495.3	COG0519	GMP synthase, PP-ATPase domain/subunit	315
2918748165	315	58.14	17	201	41	190	2.4e-09	31.8	COG2253	Predicted nucleotidyltransferase component of viral defense system	258
2918748167	308	98.67	1	302	1	297	1.3e-64	213.6	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918748168	328	96.55	4	327	9	316	1.2e-92	305	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918748169	713	99.53	4	624	2	632	0.0e+00	529.8	COG1042	Acyl-CoA synthetase (NDP forming)	598
2918748170	387	97.24	2	387	8	395	7.5e-129	425	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918748171	289	81.76	146	288	17	146	1.6e-25	83	COG2030	Acyl dehydratase	159
2918748172	249	98.88	3	248	3	267	9.4e-77	252.9	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918748173	272	96.23	5	262	11	265	5.6e-78	256.6	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918748174	398	99.75	1	398	1	393	0.0e+00	434.7	COG0183	Acetyl-CoA acetyltransferase	392
2918748175	421	97.76	1	406	10	401	2.4e-48	159.4	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2918748176	327	97.18	4	325	7	316	1.5e-76	252.1	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918748177	351	51.14	169	351	106	217	1.0e-03	11.8	COG1878	Kynurenine formamidase	218
2918748178	271	89.38	1	267	28	271	1.0e-77	255.7	COG3777	Hydroxyacyl-ACP dehydratase HTD2, hotdog domain	273
2918748179	270	96.49	7	269	1	275	4.3e-69	227.4	COG2301	Citrate lyase beta subunit	283
2918748181	189	78.95	1	189	11	175	1.4e-21	72.8	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918748182	305	80.97	13	299	2	218	3.9e-38	126.3	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918748183	323	92.54	18	289	2	249	1.7e-41	137.2	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918748184	302	97.01	3	292	5	296	1.1e-66	220.2	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918748185	250	99.25	2	248	2	267	1.6e-67	222.6	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918748186	223	96.74	4	210	1	208	1.9e-45	150	COG0625	Glutathione S-transferase	211
2918748187	73	20.44	1	73	261	334	1.4e-22	74.8	COG4962	Pilus assembly protein, ATPase of CpaF family	355
2918748188	434	40.98	1	209	8	207	1.6e-70	127.8	COG3119	Arylsulfatase A or related enzyme	475
2918748188	434	41.6	219	423	266	468	1.6e-70	110.2	COG3119	Arylsulfatase A or related enzyme	475
2918748189	323	96.87	4	322	9	317	6.3e-71	233.7	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918748190	455	28.28	14	170	4	141	5.2e-73	128.5	COG3119	Arylsulfatase A or related enzyme	475
2918748190	455	49.59	177	427	209	450	5.2e-73	111.7	COG3119	Arylsulfatase A or related enzyme	475
2918748191	271	87.38	1	267	32	294	3.1e-36	120.3	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918748193	276	80.3	148	276	20	125	2.9e-23	76.4	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918748194	239	97.12	1	238	2	237	1.3e-48	160.4	COG2872	Ser-tRNA(Ala) deacylase AlaX (editing enzyme)	241
2918748195	312	96.68	5	304	7	297	3.1e-40	132.9	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2918748196	371	95.45	1	365	13	411	3.9e-70	231.7	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
2918748197	322	98.43	3	322	4	317	1.1e-85	282.2	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918748198	302	96.35	2	300	2	291	6.9e-62	204.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918748200	129	90.44	2	129	12	134	4.8e-25	82.7	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
2918748201	301	78.62	5	295	31	280	6.3e-30	98.5	COG0657	Acetyl esterase/lipase	312
2918748202	120	83.21	1	117	16	129	3.4e-08	27.9	COG4319	Ketosteroid isomerase homolog	137
2918748203	125	81.67	14	125	8	105	1.2e-26	87.4	COG1733	DNA-binding transcriptional regulator, HxlR family	120
2918748205	51	36.84	1	48	83	131	2.0e-05	19.5	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918748207	253	93.7	8	250	3	240	2.0e-72	238.2	COG1121	ABC-type Mn2+/Zn2+ transport system, ATPase component	254
2918748208	291	97.83	4	280	5	274	7.6e-68	223.5	COG1108	ABC-type Mn2+/Zn2+ transport system, permease component	274
2918748209	301	95.74	7	299	13	304	1.4e-82	272	COG0803	ABC-type Zn uptake system ZnuABC, Zn-binding component ZnuA	303
2918748210	326	99.39	4	324	1	324	7.6e-108	355.5	COG0523	GTPase, G3E family	323
2918748211	697	97.36	2	697	22	795	2.9e-72	239.3	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2918748213	210	68.86	14	209	43	199	1.4e-38	127.4	COG3485	Protocatechuate 3,4-dioxygenase beta subunit	226
2918748214	206	97.8	32	204	3	180	3.9e-26	86.6	COG1514	2'-5' RNA ligase	180
2918748215	166	86.76	4	160	17	134	1.5e-14	48.7	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
2918748216	357	92.11	58	354	3	247	8.9e-32	105.2	COG1801	Uncharacterized conserved protein YecE, DUF72 family	263
2918748217	499	39.74	84	492	364	603	7.0e-58	191.5	COG4191	Signal transduction histidine kinase regulating C4-dicarboxylate transport system	603
2918748218	213	97.03	9	210	3	198	3.4e-71	233.6	COG4566	Two-component response regulator, FixJ family, consists of REC and HTH domains	202
2918748219	167	96.45	27	166	3	138	6.4e-34	111.8	COG3193	Uncharacterized conserved protein GlcG, DUF336 family	141
2918748220	231	47.27	129	227	108	263	5.8e-28	36.6	COG0666	Ankyrin repeat	235
2918748220	231	61.21	29	181	76	277	5.8e-28	65.7	COG0666	Ankyrin repeat	235
2918748221	214	95.24	1	203	1	200	7.7e-46	151.1	COG2808	Predicted FMN-binding regulatory protein PaiB	209
2918748223	369	95.42	7	155	8	153	5.3e-56	182.9	COG0590	tRNA(Arg) A34 adenosine deaminase TadA	152
2918748224	319	94.25	1	303	11	305	3.9e-73	240.8	COG1619	Muramoyltetrapeptide carboxypeptidase LdcA (peptidoglycan recycling)	313
2918748228	125	51.72	1	125	2	121	4.7e-21	69.9	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918748229	407	67.26	9	402	127	391	1.6e-67	222.9	COG0642	Signal transduction histidine kinase	336
2918748230	202	55.4	1	202	154	348	6.8e-51	168.2	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
2918748231	284	98.15	18	284	4	268	9.6e-59	193.5	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
2918748232	1166	84.54	21	204	25	199	8.5e-23	75.7	COG5278	Extracellular (periplasmic) sensor domain CHASE3 (specificity unknown)	207
2918748232	1166	88.72	891	1021	6	123	7.6e-80	58.9	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918748232	1166	91.73	367	895	6	127	7.6e-80	68.1	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918748232	1166	94.74	1038	1165	4	129	7.6e-80	131.9	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918748233	780	8.26	186	263	8	63	1.3e-81	38.5	COG1199	Rad3-related DNA helicase	654
2918748233	780	14.75	306	462	183	282	1.3e-81	24.5	COG1199	Rad3-related DNA helicase	654
2918748233	780	40.86	467	765	381	657	1.3e-81	204.4	COG1199	Rad3-related DNA helicase	654
2918748234	202	90	12	200	17	196	8.6e-19	62.9	COG3145	Alkylated DNA repair dioxygenase AlkB	194
2918748235	237	93.07	3	200	8	195	6.1e-52	170.4	COG1573	Uracil-DNA glycosylase	202
2918748237	470	98.43	15	454	5	444	0.0e+00	507.5	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
2918748238	410	98.97	2	402	4	389	5.8e-123	405.1	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
2918748239	242	98.21	2	229	3	221	4.2e-66	217.4	COG0132	Dethiobiotin synthetase	223
2918748240	349	97.81	1	327	1	313	4.3e-114	375.4	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
2918748241	330	76.52	185	320	21	121	2.9e-24	79.6	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918748244	147	96.23	1	147	4	156	9.6e-30	99.2	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2918748245	775	98.91	47	770	4	726	0.0e+00	637.6	COG2217	Cation transport ATPase	713
2918748246	45	74.14	1	45	1	43	2.4e-15	51.1	COG3197	Uncharacterized protein, possibly involved in nitrogen fixation	58
2918748247	479	96.49	1	478	10	476	0.0e+00	803.7	COG3278	Cbb3-type cytochrome oxidase, subunit 1	482
2918748248	209	94.74	8	209	3	218	1.1e-95	310.1	COG2993	Cbb3-type cytochrome oxidase, cytochrome c subunit	227
2918748249	46	78.33	1	46	5	51	8.1e-09	30.5	COG4736	Cbb3-type cytochrome oxidase, subunit 3	60
2918748250	303	43.9	212	302	67	138	1.7e-38	43.5	COG2010	Cytochrome c, mono- and diheme variants	150
2918748250	303	83.54	81	223	8	144	1.7e-38	87	COG2010	Cytochrome c, mono- and diheme variants	150
2918748251	487	94.96	44	456	3	379	2.8e-109	360.1	COG0348	Polyferredoxin	386
2918748252	97	32.56	12	87	4	59	9.6e-12	39.4	COG3198	Uncharacterized protein	172
2918748254	470	98.57	23	462	6	419	1.5e-130	430.4	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
2918748255	234	91.1	1	232	7	221	1.8e-26	87.7	COG2836	Sulfite exporter TauE/SafE	232
2918748256	783	97.6	2	783	19	792	0.0e+00	1252.8	COG3957	Phosphoketolase	793
2918748258	395	84.14	2	261	43	286	3.7e-78	257.3	COG1398	Fatty-acid desaturase	289
2918748260	169	96.86	1	149	4	157	1.0e-31	105.6	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2918748261	194	88.36	1	182	9	175	2.8e-19	64.4	COG3945	Hemerythrin-like domain	189
2918748263	81	17.31	7	81	35	101	1.9e-03	12	COG2309	Leucyl aminopeptidase (aminopeptidase T)	385
2918748266	171	94.02	3	171	6	178	8.9e-30	98.8	COG4970	Tfp pilus assembly protein FimT	181
2918748267	1032	71.86	106	1015	247	1002	8.0e-46	147.3	COG3419	Tfp pilus assembly protein, tip-associated adhesin PilY1	1036
2918748269	390	62.27	14	383	8	210	9.9e-20	65.3	COG4966	Tfp pilus assembly protein PilW	318
2918748270	199	89.09	5	156	6	152	1.4e-21	71.4	COG4967	Tfp pilus assembly protein PilV	162
2918748271	138	92.09	6	137	4	131	5.1e-32	105.8	COG4968	Tfp pilus assembly protein PilE	139
2918748275	579	91.91	7	257	11	260	8.0e-32	103.3	COG0631	Serine/threonine protein phosphatase PrpC	262
2918748276	270	96.23	1	267	4	258	1.3e-50	166.4	COG2116	Formate/nitrite transporter FocA, FNT family	265
2918748277	274	95.49	18	270	3	235	4.6e-82	269.9	COG0007	Uroporphyrinogen-III methylase (siroheme synthase)	244
2918748280	287	90.46	10	282	13	268	1.4e-09	29.9	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918748281	164	20.12	10	100	59	91	2.2e-12	26.8	COG2010	Cytochrome c, mono- and diheme variants	150
2918748281	164	21.95	116	164	106	141	2.2e-12	14	COG2010	Cytochrome c, mono- and diheme variants	150
2918748282	700	95.1	20	698	25	606	0.0e+00	537.5	COG3284	Transcriptional regulator of acetoin/glycerol metabolism	606
2918748283	310	97.8	1	310	4	270	1.4e-28	93.7	COG1235	Phosphoribosyl 1,2-cyclic phosphodiesterase	269
2918748284	704	12.03	391	456	424	481	4.9e-66	20.3	COG3901	Regulator of nitric oxide reductase transcription	482
2918748284	704	79.67	2	409	27	410	4.9e-66	199.2	COG3901	Regulator of nitric oxide reductase transcription	482
2918748285	335	86.39	6	328	38	329	1.2e-69	229.3	COG1477	Thiamine biosynthesis lipoprotein ApbE	337
2918748287	597	80.47	2	597	148	769	2.0e-113	374.2	COG4993	Glucose dehydrogenase	773
2918748288	510	96.39	5	446	5	431	7.6e-39	128.7	COG3182	Uncharacterized iron-regulated membrane protein	442
2918748290	819	91.95	116	810	32	762	1.8e-106	351.8	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2918748291	326	97.83	4	326	8	323	3.9e-91	300	COG3712	Periplasmic ferric-dicitrate binding protein FerR, regulates iron transport through sigma-19	322
2918748292	167	85.48	3	166	15	173	7.0e-37	121.5	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2918748294	174	72.94	18	160	3	126	3.7e-14	47.5	COG0645	Predicted kinase	170
2918748295	302	96.35	9	302	5	294	1.5e-68	226.4	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918748296	287	88.77	1	274	2	246	5.7e-41	135.4	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
2918748299	232	91.39	34	225	13	203	2.8e-17	58.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918748301	131	95.62	2	131	2	132	3.1e-30	99.8	COG2764	Uncharacterized conserved protein PhnB, glyoxalase superfamily	136
2918748302	225	20.11	5	56	50	87	3.6e-34	2	COG2020	Protein-S-isoprenylcysteine O-methyltransferase Ste14	187
2918748302	225	97.88	36	225	5	189	3.6e-34	113.2	COG2020	Protein-S-isoprenylcysteine O-methyltransferase Ste14	187
2918748305	425	76.73	75	424	69	378	2.7e-50	166.4	COG1680	CubicO group peptidase, beta-lactamase class C family	390
2918748306	501	85.86	1	501	41	544	0.0e+00	558.5	COG4716	Myosin-crossreactive antigen  (function unknown)	587
2918748307	178	72.84	9	171	39	156	4.7e-08	28.3	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2918748311	174	90.42	15	174	10	160	1.9e-42	139.2	COG0597	Lipoprotein signal peptidase	167
2918748313	180	66.67	12	173	61	184	6.9e-10	34	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
2918748314	107	80.83	7	107	9	105	2.5e-17	56.8	COG1733	DNA-binding transcriptional regulator, HxlR family	120
2918748315	310	94.98	1	308	15	317	5.7e-79	260.1	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918748316	415	98.25	19	415	4	395	3.1e-104	343.8	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918748317	522	96.65	2	519	8	556	8.5e-106	349.1	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2918748318	341	98.67	1	319	1	297	6.0e-56	181.9	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918748322	277	39.95	27	268	103	249	2.8e-06	22.5	COG0457	Tetratricopeptide (TPR) repeat	291
2918748323	283	96.77	2	281	8	277	3.5e-129	424.4	COG2877	3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase	279
2918748324	325	95.99	1	315	3	337	2.3e-77	251.9	COG0002	N-acetyl-gamma-glutamylphosphate reductase	349
2918748325	294	96.01	4	292	1	289	5.0e-54	178.7	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918748326	339	79.55	214	338	21	125	2.1e-23	76.2	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918748327	246	89.81	15	236	4	197	1.9e-30	100.9	COG0778	Nitroreductase	207
2918748328	550	95.95	15	548	16	560	1.0e-98	325.8	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2918748329	147	86.16	1	146	17	153	1.9e-20	67.4	COG2030	Acyl dehydratase	159
2918748330	387	98.75	1	386	2	395	3.7e-94	310.7	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918748331	389	96.99	2	385	9	395	2.9e-120	396.7	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918748332	322	98.12	1	321	4	316	1.2e-94	311.7	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918748333	260	99.19	13	258	2	245	2.5e-49	162.1	COG1414	DNA-binding transcriptional regulator, IclR family	246
2918748334	259	99.19	13	258	2	245	1.0e-46	153.6	COG1414	DNA-binding transcriptional regulator, IclR family	246
2918748335	417	99	14	417	5	401	6.0e-120	395.4	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2918748336	289	91.3	1	279	1	252	2.1e-46	153.1	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
2918748337	313	99.09	7	311	2	329	1.4e-71	236	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2918748338	293	97.34	1	288	1	293	1.4e-57	190.4	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918748339	208	88.52	1	208	13	197	1.9e-23	79.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918748340	167	95.35	1	162	4	167	9.0e-19	62.6	COG2318	Uncharacterized damage-inducible protein DinB (forms a four-helix bundle)	172
2918748341	153	67.2	4	147	60	184	2.1e-31	104.2	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
2918748343	304	95.93	9	294	12	294	4.3e-29	96.8	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918748344	195	77.99	1	178	13	175	8.3e-26	86.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918748345	97	80.43	1	83	13	86	3.3e-07	25.4	COG2350	Uncharacterized conserved protein YciI, contains a putative active-site phosphohistidine	92
2918748346	201	97.87	11	191	3	186	1.5e-74	244.3	COG2818	3-methyladenine DNA glycosylase Tag	188
2918748347	480	49.61	285	480	4	193	1.4e-33	24.4	COG0477	MFS family permease	338
2918748347	480	81.98	36	311	8	321	1.4e-33	92	COG0477	MFS family permease	338
2918748348	326	98.34	23	322	2	297	5.1e-49	162.4	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918748349	256	82.79	19	236	2	179	8.6e-09	29.9	COG0625	Glutathione S-transferase	211
2918748350	218	88.24	4	216	6	155	2.1e-29	96.9	COG0262	Dihydrofolate reductase	167
2918748352	97	91.86	5	87	5	83	2.0e-04	15.9	COG2161	Antitoxin component YafN of the YafNO toxin-antitoxin module, PHD/YefM family	86
2918748353	138	88.24	6	138	13	132	8.3e-29	95	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
2918748354	384	98.65	1	382	5	370	4.5e-110	362.5	COG3616	D-serine deaminase, pyridoxal phosphate-dependent	368
2918748355	328	97.49	5	327	6	316	9.8e-78	256.1	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918748356	224	96.97	12	218	3	226	2.9e-23	77.2	COG1011	FMN phosphatase YigB, HAD superfamily	229
2918748357	308	98.67	2	302	1	297	3.6e-58	192.4	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918748358	52	13.57	1	45	122	156	2.9e-04	13.5	COG0688	Phosphatidylserine decarboxylase	239
2918748359	187	71.33	18	175	24	130	8.4e-12	40.2	COG0526	Thiol-disulfide isomerase or thioredoxin	127
2918748361	182	73.89	3	163	52	201	2.3e-33	110.2	COG3917	2-hydroxychromene-2-carboxylate isomerase	203
2918748362	329	98.75	4	328	4	318	2.2e-60	199.1	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918748363	218	94.05	3	202	8	181	4.0e-44	145.1	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
2918748364	514	96.48	1	512	13	560	1.6e-115	381.2	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2918748365	232	89.95	2	207	6	193	7.6e-22	73.6	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918748366	406	97.74	1	403	1	390	1.9e-98	324.8	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918748367	358	98.17	10	350	5	325	6.0e-92	302.8	COG3173	Predicted  kinase, aminoglycoside phosphotransferase (APT) family	321
2918748368	325	98.43	3	324	4	317	4.0e-72	237.7	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918748369	238	95.37	8	233	5	210	3.8e-29	96.5	COG0778	Nitroreductase	207
2918748370	553	28.85	10	226	16	178	1.7e-105	185.7	COG2936	Predicted acyl esterase	563
2918748370	553	59.65	215	549	228	564	1.7e-105	169	COG2936	Predicted acyl esterase	563
2918748371	387	97.49	3	387	6	394	5.7e-121	399	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918748372	139	86.52	3	139	15	136	2.0e-27	90.3	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
2918748373	719	25.53	627	715	188	271	7.9e-95	8	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
2918748373	719	91.7	10	312	14	256	3.7e-58	191.9	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918748373	719	98.78	322	657	4	328	7.9e-95	310	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
2918748374	402	99.24	2	402	4	394	3.7e-108	356.7	COG0183	Acetyl-CoA acetyltransferase	392
2918748375	380	97.26	1	379	6	395	1.8e-108	357.7	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2918748376	222	96.3	1	221	3	210	3.4e-25	83.7	COG0778	Nitroreductase	207
2918748377	295	61.01	146	291	36	132	6.3e-16	48.3	COG2030	Acyl dehydratase	159
2918748378	318	94.65	9	315	16	316	5.1e-55	181.8	COG0657	Acetyl esterase/lipase	312
2918748379	538	98.21	1	494	5	442	7.9e-109	359.2	COG2072	Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD	443
2918748380	295	92.39	13	283	1	255	1.8e-38	127.2	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
2918748381	198	89.47	4	196	18	204	7.9e-22	73.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918748382	296	96.7	10	281	8	271	4.5e-80	263.9	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
2918748383	259	96.97	3	258	5	260	4.1e-23	74.8	COG3971	2-keto-4-pentenoate hydratase	264
2918748385	353	99.71	1	344	1	349	0.0e+00	475.6	COG3839	ABC-type sugar transport system, ATPase component	338
2918748387	277	97.56	9	258	3	242	2.3e-62	204.8	COG1414	DNA-binding transcriptional regulator, IclR family	246
2918748388	303	94.97	14	303	10	292	2.1e-62	205.9	COG1175	ABC-type sugar transport system, permease component	295
2918748389	277	96.82	1	276	10	283	7.6e-81	266.4	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
2918748390	440	95.03	17	439	7	427	1.5e-41	137.9	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
2918748391	285	91.9	4	272	3	263	2.2e-62	205.3	COG0169	Shikimate 5-dehydrogenase	283
2918748392	339	93.45	1	333	18	345	2.9e-30	100.5	COG0673	Predicted dehydrogenase	342
2918748393	150	54.04	23	148	33	119	1.9e-09	31.8	COG3837	Uncharacterized conserved protein, cupin superfamily	161
2918748394	458	52.74	250	455	4	205	2.2e-39	35.3	COG0477	MFS family permease	338
2918748394	458	58.22	21	262	4	226	2.2e-39	99.5	COG0477	MFS family permease	338
2918748395	255	99.25	6	254	2	267	7.5e-58	190.9	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918748396	254	98.88	8	252	2	266	1.9e-75	248.6	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918748398	262	95.09	1	251	5	256	8.4e-56	183.9	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918748399	298	90.91	8	298	29	308	1.3e-25	84.9	COG1073	Fermentation-respiration switch protein FrsA, has esterase activity, DUF1100 family	299
2918748400	206	94.59	5	199	7	181	6.8e-43	141	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
2918748401	137	68.12	69	128	5	51	1.8e-09	16.7	COG1942	Phenylpyruvate tautomerase PptA, 4-oxalocrotonate tautomerase family	69
2918748401	137	75.36	2	68	3	54	1.8e-09	13.6	COG1942	Phenylpyruvate tautomerase PptA, 4-oxalocrotonate tautomerase family	69
2918748403	297	78.3	7	296	66	314	7.7e-53	174.8	COG0657	Acetyl esterase/lipase	312
2918748404	327	78.46	42	322	19	222	1.1e-32	108.2	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2918748405	159	88.33	1	119	7	112	6.7e-23	75.2	COG1733	DNA-binding transcriptional regulator, HxlR family	120
2918748406	289	77.27	167	288	24	125	4.4e-31	101.5	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918748407	307	98.99	1	302	3	297	3.0e-107	353.1	COG3246	Uncharacterized conserved protein, DUF849 family	298
2918748408	250	98.88	3	248	2	266	1.1e-67	223	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918748409	451	48.56	255	440	8	193	2.6e-34	16.1	COG0477	MFS family permease	338
2918748409	451	76.24	21	300	4	295	2.6e-34	99.6	COG0477	MFS family permease	338
2918748410	123	60.87	64	122	18	59	8.5e-12	9.1	COG1942	Phenylpyruvate tautomerase PptA, 4-oxalocrotonate tautomerase family	69
2918748410	123	88.41	1	62	1	61	8.5e-12	28.7	COG1942	Phenylpyruvate tautomerase PptA, 4-oxalocrotonate tautomerase family	69
2918748411	51	19.37	1	51	72	126	4.5e-07	24.5	COG2801	Transposase InsO and inactivated derivatives	232
2918748412	322	96.87	2	319	8	316	5.5e-85	279.8	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918748413	271	95.85	6	258	6	259	1.3e-57	189.8	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918748414	404	98.5	1	404	7	401	5.0e-122	402.4	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2918748415	271	98.88	2	267	3	267	2.6e-74	244.8	COG0345	Pyrroline-5-carboxylate reductase	266
2918748416	110	8.93	14	110	705	773	9.3e-15	48.8	COG4230	Delta 1-pyrroline-5-carboxylate dehydrogenase	769
2918748418	192	88.55	1	150	17	163	2.7e-19	64.5	COG3467	Nitroimidazol reductase NimA or a related FMN-containing flavoprotein, pyridoxamine 5'-phosphate oxidase superfamily	166
2918748419	364	96.56	2	346	3	339	3.7e-97	320	COG2055	Malate/lactate/ureidoglycolate dehydrogenase, LDH2 family	349
2918748420	408	98.09	14	387	4	362	5.3e-38	125.5	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918748421	338	97.52	3	308	7	321	1.2e-81	269.2	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918748422	281	96.35	1	281	7	296	3.0e-78	258.1	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2918748423	234	98.73	3	234	3	236	3.9e-85	279.5	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2918748424	258	98.03	10	255	5	253	2.1e-86	284	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2918748425	227	64.12	94	206	37	120	1.2e-11	38.9	COG1917	Cupin domain protein related to quercetin dioxygenase	131
2918748426	203	63.85	18	157	2	84	2.3e-14	49	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918748427	49	4.01	6	49	742	772	3.3e-07	23.9	COG4230	Delta 1-pyrroline-5-carboxylate dehydrogenase	769
2918748428	513	98.84	1	341	5	346	0.0e+00	430.5	COG1171	Threonine dehydratase	347
2918748429	253	96.64	12	253	6	235	1.2e-48	160.5	COG3473	Maleate cis-trans isomerase	238
2918748430	544	98.03	55	542	6	452	1.3e-120	397.9	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
2918748431	481	98.34	1	475	4	476	3.2e-118	390.4	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
2918748432	231	94.58	12	176	3	159	4.5e-33	109.3	COG3467	Nitroimidazol reductase NimA or a related FMN-containing flavoprotein, pyridoxamine 5'-phosphate oxidase superfamily	166
2918748433	537	96.7	1	537	17	543	0.0e+00	473.5	COG0405	Gamma-glutamyltranspeptidase	539
2918748435	323	96.55	2	320	9	316	5.1e-84	276.6	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918748436	533	96.72	2	533	10	569	3.7e-81	268	COG3653	N-acyl-D-aspartate/D-glutamate deacylase	579
2918748437	108	52.97	1	108	16	122	1.0e-22	75.4	COG4566	Two-component response regulator, FixJ family, consists of REC and HTH domains	202
2918748438	123	51.54	8	119	18	84	6.4e-04	15.6	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918748462	187	60	23	168	57	149	1.4e-17	58.7	COG1403	5-methylcytosine-specific restriction endonuclease McrA	146
2918748464	271	92.2	15	271	21	292	3.9e-30	100.2	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918748465	446	96.95	117	443	8	293	1.5e-17	59.3	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918748466	997	27.27	442	526	106	171	1.4e-57	22.8	COG2202	PAS domain	232
2918748466	997	58.26	680	819	102	242	1.4e-57	48.9	COG2202	PAS domain	232
2918748466	997	59.5	26	447	99	242	1.4e-57	65.5	COG2202	PAS domain	232
2918748466	997	64.88	512	689	80	236	1.4e-57	66.3	COG2202	PAS domain	232
2918748466	997	96.17	807	988	7	182	1.1e-53	174.9	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2918748467	258	97.74	2	255	7	265	2.3e-70	231.7	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918748468	410	96.99	1	406	6	392	1.1e-92	305.9	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918748469	322	99.06	1	321	1	316	1.6e-92	304.8	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918748470	409	99.25	1	409	4	401	0.0e+00	503.1	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2918748471	205	95.81	5	205	1	206	2.2e-34	114	COG0625	Glutathione S-transferase	211
2918748472	274	95.71	6	274	11	278	6.5e-41	135.3	COG3618	Predicted metal-dependent hydrolase, TIM-barrel fold	279
2918748473	191	81.72	7	175	31	182	2.3e-13	45.3	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
2918748474	293	96.95	18	291	7	292	2.6e-26	87.6	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918748475	323	98.34	15	313	2	297	6.6e-51	168.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918748476	226	87.61	10	220	24	214	2.0e-19	64.6	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2918748478	442	96.05	1	441	6	443	2.8e-94	311	COG2079	2-methylcitrate dehydratase PrpD	453
2918748479	698	98.74	5	619	5	630	0.0e+00	462.2	COG1042	Acyl-CoA synthetase (NDP forming)	598
2918748480	268	96.6	1	264	4	259	1.7e-70	232	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918748481	332	98.43	10	331	4	317	1.6e-99	327.7	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918748482	272	97.15	21	262	1	239	5.9e-45	147.7	COG1414	DNA-binding transcriptional regulator, IclR family	246
2918748483	326	96.87	3	323	9	317	2.1e-89	294.3	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918748484	281	97.29	23	281	8	294	1.2e-27	91.9	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918748485	297	98.01	1	295	1	295	4.1e-65	215.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918748486	279	98.57	1	276	4	279	6.3e-47	155.2	COG3618	Predicted metal-dependent hydrolase, TIM-barrel fold	279
2918748487	266	98.88	3	264	3	267	8.8e-66	216.9	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918748488	318	96.87	1	317	9	317	3.5e-82	270.8	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918748489	176	87.63	5	176	20	182	7.6e-17	56.7	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
2918748491	296	76.52	176	295	23	123	2.7e-26	86.2	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918748492	519	99	1	504	2	498	0.0e+00	465.1	COG1070	Sugar (pentulose or hexulose) kinase	502
2918748493	450	98.66	8	450	6	448	0.0e+00	486.4	COG2610	H+/gluconate symporter or related permease	442
2918748494	343	98.8	16	343	1	330	2.7e-96	317.5	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
2918748509	209	86.08	2	209	3	206	3.3e-52	172.1	COG0412	Dienelactone hydrolase	236
2918748510	222	93.27	14	218	7	200	1.0e-59	196.1	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
2918748512	518	98.5	56	509	4	265	2.0e-71	235.2	COG0860	N-acetylmuramoyl-L-alanine amidase	231
2918748513	169	95.97	17	167	5	147	6.9e-42	137.5	COG0802	tRNA A37 threonylcarbamoyladenosine biosynthesis protein TsaE	149
2918748514	321	90.03	1	317	35	341	2.0e-119	393.4	COG1600	Epoxyqueuosine reductase  QueG (queuosine biosynthesis)	337
2918748515	301	96.17	2	299	7	307	2.8e-45	149.2	COG0679	Predicted permease	311
2918748516	324	96.24	1	322	9	315	5.6e-88	289.7	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918748517	303	97.67	4	303	7	299	3.4e-112	369.2	COG4974	Site-specific recombinase XerD	300
2918748518	254	93.23	13	254	3	250	3.6e-60	198.6	COG1801	Uncharacterized conserved protein YecE, DUF72 family	263
2918748519	323	96.87	1	322	10	318	2.1e-90	297.8	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918748520	196	89	4	196	11	196	1.2e-20	69.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918748521	377	99.49	1	377	3	394	6.8e-126	415.2	COG0183	Acetyl-CoA acetyltransferase	392
2918748522	158	92.45	2	158	12	158	8.1e-39	127.1	COG2030	Acyl dehydratase	159
2918748523	270	95.52	2	269	9	264	9.2e-103	337.7	COG2833	Uncharacterized conserved protein, contains ferritin-like DUF455 domain	268
2918748524	174	96.05	1	174	6	175	6.8e-68	222.3	COG0663	Carbonic anhydrase or acetyltransferase, isoleucine patch superfamily	176
2918748525	332	97.91	2	317	6	286	1.1e-73	242.6	COG1281	Redox-regulated molecular chaperone, HSP33 family	286
2918748527	234	93.58	8	186	10	184	2.1e-21	71.1	COG3172	Nicotinamide riboside kinase	187
2918748528	208	85.59	5	205	21	210	1.2e-35	117.7	COG3201	Nicotinamide riboside transporter PnuC	222
2918748529	92	75.42	1	92	23	111	1.0e-23	78.2	COG2919	Cell division protein FtsB	117
2918748530	427	99.76	1	426	1	424	0.0e+00	669.9	COG0148	Enolase	423
2918748531	96	98.96	1	96	1	95	1.2e-31	103.6	COG5470	Uncharacterized conserved protein, DUF1330 family	96
2918748532	285	97.85	1	281	5	277	3.3e-130	427.8	COG2877	3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase	279
2918748533	559	99.81	2	548	1	534	0.0e+00	805.7	COG0504	CTP synthase (UTP-ammonia lyase)	533
2918748534	407	99.25	3	403	2	399	4.1e-127	419.1	COG0452	Phosphopantothenoylcysteine synthetase/decarboxylase	392
2918748536	148	97.32	1	148	5	149	2.9e-54	177.5	COG0756	dUTPase	148
2918748537	166	89.61	2	165	8	145	2.0e-17	58	COG3133	Outer membrane lipoprotein SlyB	154
2918748538	174	86.44	1	166	1	153	4.8e-31	102.1	COG1047	FKBP-type peptidyl-prolyl cis-trans isomerase 2	174
2918748539	381	97.66	1	381	6	381	9.1e-87	286.2	COG2850	Ribosomal protein L16 Arg81 hydroxylase, contains JmjC domain	383
2918748542	258	95.97	1	246	4	265	1.9e-36	120.2	COG1235	Phosphoribosyl 1,2-cyclic phosphodiesterase	269
2918748543	364	97.38	6	364	9	342	1.3e-78	259.2	COG3317	Uncharacterized lipoprotein	342
2918748544	296	97.66	1	296	4	295	4.4e-110	361.9	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
2918748545	189	54.12	4	186	44	194	2.3e-13	45.5	COG0500	SAM-dependent methyltransferase	257
2918748547	407	46.74	6	219	25	203	6.8e-23	43.6	COG0477	MFS family permease	338
2918748547	407	50.39	211	405	4	196	6.8e-23	37.9	COG0477	MFS family permease	338
2918748548	665	98.91	13	665	4	637	0.0e+00	666.4	COG0187	DNA gyrase/topoisomerase IV, subunit B	635
2918748550	373	9.97	213	260	117	154	1.6e-11	2.4	COG3055	N-acetylneuraminic acid mutarotase	381
2918748550	373	9.97	253	307	321	358	1.6e-11	.9	COG3055	N-acetylneuraminic acid mutarotase	381
2918748550	373	11.55	156	212	320	363	1.6e-11	10.8	COG3055	N-acetylneuraminic acid mutarotase	381
2918748550	373	19.16	270	358	82	154	1.6e-11	6.4	COG3055	N-acetylneuraminic acid mutarotase	381
2918748550	373	22.31	68	158	71	155	1.6e-11	11.9	COG3055	N-acetylneuraminic acid mutarotase	381
2918748551	798	87.33	11	797	10	719	0.0e+00	740.1	COG0188	DNA gyrase/topoisomerase IV, subunit A	804
2918748553	367	92.45	94	361	8	252	2.7e-59	195.1	COG2220	L-ascorbate metabolism protein UlaG, beta-lactamase superfamily	258
2918748555	176	85.92	1	162	4	180	6.5e-30	98.2	COG1335	Nicotinamidase-related amidase	205
2918748557	223	92.11	1	219	15	224	1.0e-67	222.8	COG0765	ABC-type amino acid transport system, permease component	222
2918748558	217	91.67	1	214	18	226	7.3e-72	236.3	COG0765	ABC-type amino acid transport system, permease component	222
2918748559	268	95.41	3	268	6	275	1.7e-54	179.8	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2918748560	251	99.17	5	245	2	241	1.8e-115	378.9	COG1126	ABC-type polar amino acid transport system, ATPase component	240
2918748561	247	48.56	29	247	140	274	4.5e-09	30.7	COG1082	Sugar phosphate isomerase/epimerase	274
2918748562	317	98.1	8	315	1	310	6.9e-72	236.7	COG0524	Sugar or nucleoside kinase, ribokinase family	311
2918748563	327	97.55	3	323	5	323	8.5e-96	315.1	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
2918748564	341	99.4	7	341	1	332	1.6e-86	285.3	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
2918748565	152	91.91	6	152	10	134	3.6e-21	70.2	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
2918748566	328	92.6	1	307	11	323	1.9e-64	213.1	COG1305	Transglutaminase-like enzyme, putative cysteine protease	319
2918748567	907	95.49	73	565	22	487	0.0e+00	497.4	COG2308	Uncharacterized conserved protein, circularly permuted ATPgrasp superfamily	488
2918748567	907	98.4	580	900	2	309	6.5e-48	158.1	COG2307	Uncharacterized conserved protein, Alpha-E superfamily	313
2918748568	1178	88.46	1	311	15	313	3.3e-57	188.6	COG1305	Transglutaminase-like enzyme, putative cysteine protease	319
2918748568	1178	99.38	284	1178	2	804	0.0e+00	1041.2	COG4196	Uncharacterized conserved protein, DUF2126 family	808
2918748569	823	91.8	474	818	26	305	2.3e-69	227.6	COG2333	Metal-dependent hydrolase, beta-lactamase superfamily II	293
2918748570	497	96.31	1	493	12	481	0.0e+00	695.5	COG2308	Uncharacterized conserved protein, circularly permuted ATPgrasp superfamily	488
2918748571	318	98.72	1	318	1	309	4.4e-97	320.1	COG2307	Uncharacterized conserved protein, Alpha-E superfamily	313
2918748572	555	73.38	30	517	84	491	1.6e-48	160.2	COG2194	Phosphoethanolamine transferase for periplasmic glucans (OPG), alkaline phosphatase superfamily	555
2918748573	153	74.85	26	153	36	163	2.4e-15	51.1	COG3807	SH3-like domain	171
2918748574	497	98	1	497	6	496	0.0e+00	732.5	COG0554	Glycerol kinase	499
2918748575	255	98.43	1	254	3	252	5.7e-80	263.3	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
2918748576	534	93.48	7	529	11	512	0.0e+00	564.7	COG0578	Glycerol-3-phosphate dehydrogenase	532
2918748577	357	99.14	1	344	3	349	1.9e-88	291.8	COG3839	ABC-type sugar transport system, ATPase component	338
2918748578	356	93.43	4	352	17	343	4.3e-97	320	COG3839	ABC-type sugar transport system, ATPase component	338
2918748580	296	94.3	1	291	12	292	3.9e-67	221.5	COG1175	ABC-type sugar transport system, permease component	295
2918748581	270	94.35	3	270	16	282	5.7e-75	247	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
2918748582	102	93.81	1	102	6	96	4.8e-31	98.4	COG5477	Predicted small integral membrane protein	97
2918748583	576	98.42	1	519	7	442	8.3e-69	227.6	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
2918748585	377	93.56	2	375	6	310	3.5e-45	148.8	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
2918748588	302	98.37	1	298	5	305	1.6e-73	242.6	COG1131	ABC-type multidrug transport system, ATPase component	293
2918748589	385	70.99	147	385	82	289	3.0e-15	50.5	COG0842	ABC-type multidrug transport system, permease component	286
2918748590	91	53.09	7	89	34	76	2.5e-09	31.9	COG0236	Acyl carrier protein	80
2918748591	359	18.53	64	317	157	376	1.2e-24	80.1	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
2918748593	208	96.15	2	208	6	205	8.1e-57	186.8	COG4339	Predicted metal-dependent phosphohydrolase, HD superfamily	208
2918748594	363	97.12	6	363	7	343	5.9e-86	283.5	COG2951	Membrane-bound lytic murein transglycosylase B	343
2918748595	673	61.24	184	555	74	280	5.3e-37	122.5	COG1305	Transglutaminase-like enzyme, putative cysteine protease	319
2918748596	323	70.26	32	323	8	300	3.6e-29	96.8	COG1721	Uncharacterized conserved protein, DUF58 family, contains vWF domain	416
2918748597	297	86.06	1	293	21	304	9.5e-86	282.6	COG0714	MoxR-like ATPase	329
2918748598	317	90.49	1	317	3	316	8.8e-99	325.5	COG0123	Acetoin utilization deacetylase AcuC or a related deacetylase	340
2918748599	426	35.92	74	423	525	830	2.0e-92	305.5	COG3264	Small-conductance mechanosensitive channel	835
2918748600	249	99.62	1	249	1	260	9.4e-91	298.3	COG2086	Electron transfer flavoprotein, alpha and beta subunits	260
2918748601	310	99.06	1	310	1	315	2.5e-107	353.9	COG2025	Electron transfer flavoprotein, alpha subunit	313
2918748603	57	16.05	7	57	4	51	5.3e-10	33.4	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
2918748604	582	61.66	37	282	20	212	9.8e-49	62	COG3509	Poly(3-hydroxybutyrate) depolymerase	312
2918748604	582	64.54	311	578	44	245	9.8e-49	97.9	COG3509	Poly(3-hydroxybutyrate) depolymerase	312
2918748605	796	50.77	318	499	24	155	9.5e-14	45.6	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2918748606	279	45.92	109	256	99	250	1.4e-56	110.1	COG0790	TPR repeat	292
2918748606	279	48.94	6	182	90	251	1.4e-56	90.4	COG0790	TPR repeat	292
2918748607	338	98.5	13	338	1	329	1.2e-87	289	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
2918748608	360	98.2	31	360	2	329	1.3e-78	259.3	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
2918748609	367	91.42	3	365	24	364	2.3e-70	231.9	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
2918748610	329	97.81	7	326	5	316	6.6e-81	266.5	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918748611	186	82.26	10	180	26	178	1.3e-12	42.8	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
2918748612	261	55.17	12	229	2	129	1.6e-32	107.2	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918748613	237	98.28	10	237	2	229	2.2e-40	133	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918748614	696	78.93	318	696	80	390	3.0e-54	179.1	COG0642	Signal transduction histidine kinase	336
2918748615	93	91.01	6	87	7	87	7.9e-04	14.6	COG3609	Transcriptional regulator, contains Arc/MetJ-type RHH (ribbon-helix-helix) DNA-binding domain	89
2918748616	89	67.68	2	89	25	91	4.7e-10	34.7	COG3668	Plasmid stabilization system protein ParE	98
2918748617	142	85.8	1	129	19	157	1.7e-11	39.5	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2918748619	195	90.43	4	195	10	198	3.6e-22	74.8	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2918748620	169	74.55	17	165	42	164	4.0e-17	55.8	COG4731	Uncharacterized conserved protein, DUF2147 family	162
2918748621	333	99.7	1	332	1	330	7.6e-97	319.3	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2918748622	234	79.1	1	226	1	212	9.1e-41	135	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918748623	278	98.31	8	278	4	293	1.0e-40	134.8	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918748624	101	43.08	10	90	2	57	2.9e-10	36.1	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2918748625	395	92.48	6	377	24	392	1.3e-68	226.2	COG3550	Serine/threonine protein kinase HipA, toxin component of the HipAB toxin-antitoxin module	392
2918748626	215	62.42	8	204	5	195	2.1e-26	87.6	COG1131	ABC-type multidrug transport system, ATPase component	293
2918748627	270	93.66	2	270	17	282	2.4e-93	307.2	COG3639	ABC-type phosphate/phosphonate transport system, permease component	283
2918748628	315	89.04	1	282	25	292	8.4e-87	285.9	COG3221	ABC-type phosphate/phosphonate transport system, periplasmic component	299
2918748629	288	96.51	2	263	3	251	2.3e-98	323.1	COG3638	ABC-type phosphate/phosphonate transport system, ATPase component	258
2918748630	385	99.47	6	385	2	376	0.0e+00	480.9	COG3454	Alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase PhnM	377
2918748631	238	96.17	1	238	5	230	1.2e-97	320.7	COG4778	Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL	235
2918748632	263	98.45	6	263	4	257	0.0e+00	445.9	COG4107	ABC-type phosphonate transport system, ATPase component	258
2918748633	298	94.5	1	283	9	283	0.0e+00	549.4	COG3627	Alpha-D-ribose 1-methylphosphonate 5-phosphate C-P lyase	291
2918748634	365	96.19	1	364	1	353	0.0e+00	581.9	COG3626	Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnI	367
2918748635	207	97.45	4	205	5	195	2.0e-58	191.8	COG3625	Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnH	196
2918748636	172	94.7	9	162	6	148	4.8e-48	157.4	COG3624	Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnG	151
2918748637	258	96.65	18	256	8	238	1.2e-52	173.3	COG2188	DNA-binding transcriptional regulator, GntR family	236
2918748638	237	22.9	174	232	43	72	4.6e-03	6.2	COG5485	Predicted ester cyclase	131
2918748638	237	29.01	1	60	4	41	4.6e-03	3.2	COG5485	Predicted ester cyclase	131
2918748639	189	92.71	3	188	4	181	3.3e-54	177.8	COG3709	Ribose 1,5-bisphosphokinase PhnN	192
2918748640	386	98.68	5	376	6	380	4.7e-79	260.5	COG3287	Uncharacterized conserved protein, contains FIST_N domain	379
2918748641	365	73.35	5	365	102	390	3.4e-31	103.7	COG0642	Signal transduction histidine kinase	336
2918748642	755	31.75	7	188	35	101	1.7e-07	23.3	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918748642	755	64.25	233	749	216	641	4.2e-110	363.2	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2918748643	328	95.48	1	328	11	327	7.7e-98	322.5	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
2918748644	723	15.84	110	276	230	334	3.5e-113	6	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2918748644	723	62.59	267	721	227	641	3.5e-113	372	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2918748645	255	95.15	1	249	5	259	3.7e-49	162.3	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918748646	300	79.55	172	299	21	125	6.2e-25	81.9	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918748647	465	99.17	2	464	4	480	1.2e-124	411.7	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
2918748648	234	94.94	1	232	3	227	5.6e-81	265.9	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2918748649	239	95.31	1	239	11	254	2.0e-77	254.3	COG4674	ABC-type uncharacterized transport system, ATPase component	249
2918748650	362	94.74	3	324	12	317	3.2e-59	195.2	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918748651	288	96.35	1	285	7	296	2.5e-59	195.9	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2918748652	408	95.36	9	385	5	353	1.3e-57	190.1	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918748653	505	95.63	1	505	17	476	1.7e-110	365.1	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
2918748654	367	82.79	6	352	7	309	2.4e-26	87.3	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918748655	144	84.96	9	143	15	127	1.3e-21	71.8	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918748657	411	94.7	122	398	2	251	4.1e-47	155.8	COG1192	Cellulose biosynthesis protein BcsQ	259
2918748658	359	63.64	95	347	6	173	5.9e-20	66.7	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
2918748659	233	25	4	219	96	143	1.3e-08	30.1	COG1432	Uncharacterized conserved protein, LabA/DUF88 family	181
2918748660	91	15.13	9	91	290	353	4.3e-03	11	COG1239	Mg-chelatase subunit ChlI	423
2918748661	630	85.67	276	627	27	283	1.1e-19	63	COG4974	Site-specific recombinase XerD	300
2918748663	42	14.29	1	42	55	94	3.4e-04	15.1	COG3618	Predicted metal-dependent hydrolase, TIM-barrel fold	279
2918748664	360	51.02	7	50	8	32	4.4e-04	13.9	COG1996	DNA-directed RNA polymerase, subunit RPC12/RpoP, contains C4-type Zn-finger	49
2918748665	310	81.57	15	277	22	229	7.3e-04	11.8	COG1462	Curli biogenesis system outer membrane secretion channel CsgG	252
2918748666	224	89.22	1	217	16	222	4.3e-42	138.8	COG1802	DNA-binding transcriptional regulator, GntR family	230
2918748667	296	96.99	1	294	4	293	8.8e-76	249.2	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
2918748668	326	94.67	7	322	7	308	1.5e-72	238.9	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918748669	333	99.09	1	331	2	326	3.4e-115	379.2	COG2376	Dihydroxyacetone kinase	323
2918748670	199	57.01	1	199	36	222	1.9e-09	31.9	COG2376	Dihydroxyacetone kinase	323
2918748671	290	97.34	1	288	5	297	5.5e-76	250.6	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2918748672	607	94.43	3	306	9	313	1.7e-74	245.9	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918748672	607	99.21	350	590	3	254	1.4e-78	258.2	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2918748673	376	93.99	14	375	12	355	3.4e-67	221.6	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918748674	250	98.31	14	250	4	236	1.9e-85	280.5	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2918748675	468	97.87	20	468	9	467	4.7e-114	376.4	COG0277	FAD/FMN-containing dehydrogenase	459
2918748676	771	88.15	40	747	96	809	7.0e-128	422.6	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
2918748677	289	96.86	2	288	9	286	6.6e-82	269.6	COG2897	3-mercaptopyruvate sulfurtransferase SseA, contains two rhodanese domains	285
2918748678	330	95.92	8	326	8	313	1.3e-82	272.1	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918748679	452	98.63	11	446	5	437	0.0e+00	456.1	COG0015	Adenylosuccinate lyase	438
2918748680	492	99.36	19	484	2	467	5.1e-117	385.5	COG0277	FAD/FMN-containing dehydrogenase	459
2918748681	273	25.61	190	260	174	236	1.2e-45	36.1	COG1414	DNA-binding transcriptional regulator, IclR family	246
2918748681	273	55.28	47	192	2	137	1.2e-45	117.4	COG1414	DNA-binding transcriptional regulator, IclR family	246
2918748682	290	91.15	2	270	19	255	3.3e-41	135.3	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2918748683	464	89.91	12	452	20	429	9.9e-80	262.1	COG2079	2-methylcitrate dehydratase PrpD	453
2918748684	772	74.37	338	674	94	386	7.5e-49	161.5	COG0642	Signal transduction histidine kinase	336
2918748685	275	81.82	138	274	18	125	6.1e-27	87.5	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918748685	275	96.99	7	137	2	130	3.2e-32	104.4	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2918748686	701	16.18	460	516	14	57	1.3e-07	4.9	COG0631	Serine/threonine protein phosphatase PrpC	262
2918748686	701	16.54	550	606	13	57	1.3e-07	4.3	COG0631	Serine/threonine protein phosphatase PrpC	262
2918748686	701	16.54	641	695	13	57	1.3e-07	5.6	COG0631	Serine/threonine protein phosphatase PrpC	262
2918748686	701	16.91	368	424	12	57	1.3e-07	6.1	COG0631	Serine/threonine protein phosphatase PrpC	262
2918748688	627	31.01	390	626	445	644	0.0e+00	160.3	COG0323	DNA mismatch repair ATPase MutL	638
2918748688	627	51.01	11	352	4	332	0.0e+00	417.5	COG0323	DNA mismatch repair ATPase MutL	638
2918748689	332	22.08	198	285	228	295	8.7e-18	15.4	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
2918748689	332	29.87	66	208	35	126	8.7e-18	41.1	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
2918748690	328	95.45	12	326	3	296	6.7e-108	354.2	COG0324	tRNA A37 N6-isopentenylltransferase MiaA	308
2918748691	216	89.04	4	216	19	221	2.2e-69	227.3	COG4181	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component	228
2918748692	318	91.91	1	318	7	324	5.9e-115	378.1	COG1171	Threonine dehydratase	347
2918748693	234	91.81	5	223	16	228	2.4e-48	158.4	COG1802	DNA-binding transcriptional regulator, GntR family	230
2918748694	291	50.5	39	281	81	231	3.7e-18	59.5	COG5285	Ectoine hydroxylase-related dioxygenase, phytanoyl-CoA dioxygenase (PhyH) family	299
2918748695	453	99.32	1	452	2	436	0.0e+00	437.6	COG4091	Predicted homoserine dehydrogenase, contains C-terminal SAF domain	438
2918748696	123	95.12	1	122	1	117	1.5e-35	116	COG3795	Uncharacterized conserved protein	123
2918748697	409	98.07	4	409	3	409	1.9e-123	406.2	COG4941	Predicted RNA polymerase sigma factor, contains C-terminal TPR domain	415
2918748698	474	90.59	3	451	15	380	9.3e-38	124.3	COG1680	CubicO group peptidase, beta-lactamase class C family	390
2918748699	867	26.08	17	120	3	135	8.4e-35	1.6	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
2918748699	867	27.45	235	387	360	499	8.4e-35	61.1	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
2918748699	867	98.82	482	866	5	508	8.4e-35	51.7	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
2918748700	847	98.59	12	841	6	773	0.0e+00	495.3	COG2366	Acyl-homoserine lactone (AHL) acylase PvdQ	768
2918748701	358	98.01	20	331	5	300	8.5e-77	252	COG0031	Cysteine synthase	300
2918748702	358	90.42	7	352	35	355	7.4e-80	262.6	COG5621	Predicted secreted hydrolase	354
2918748704	611	94.51	6	609	14	512	1.2e-97	321.6	COG0737	2',3'-cyclic-nucleotide 2'-phosphodiesterase/5'- or 3'-nucleotidase, 5'-nucleotidase family	517
2918748705	328	96.9	1	320	5	317	4.0e-82	269.9	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918748706	287	98.01	1	287	3	297	4.0e-83	273.4	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2918748707	398	97.27	15	389	4	359	4.0e-45	148.2	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918748708	238	99.58	2	238	2	237	3.2e-86	282.3	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2918748709	256	99.61	1	247	2	254	1.6e-91	300	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2918748711	399	97.42	1	399	6	383	1.1e-109	360.8	COG2942	Mannose or cellobiose epimerase, N-acyl-D-glucosamine 2-epimerase family	388
2918748712	520	49.87	271	512	2	192	9.4e-43	11	COG0477	MFS family permease	338
2918748712	520	71.02	17	273	7	278	9.4e-43	135.2	COG0477	MFS family permease	338
2918748713	447	95.74	11	382	8	344	1.5e-113	373.1	COG1566	Multidrug resistance efflux pump	352
2918748714	492	98.26	22	485	3	454	1.1e-110	364.5	COG1538	Outer membrane protein TolC	457
2918748715	178	82.71	33	169	23	132	3.6e-24	79.3	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918748716	594	99.49	14	594	3	591	0.0e+00	554	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
2918748717	157	96.48	1	154	1	137	6.5e-47	153.1	COG5319	Uncharacterized protein	142
2918748718	201	60.47	36	169	9	112	1.9e-16	54.3	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2918748720	495	98.95	3	493	4	474	0.0e+00	471.4	COG1007	NADH:ubiquinone oxidoreductase subunit 2 (chain N)	475
2918748721	492	97.79	1	492	5	491	0.0e+00	629.7	COG1008	NADH:ubiquinone oxidoreductase subunit 4 (chain M)	497
2918748722	676	99.68	10	670	2	616	0.0e+00	743.3	COG1009	NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit	606
2918748723	102	98	2	102	3	100	8.8e-38	122.3	COG0713	NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K)	100
2918748724	217	99.4	1	170	1	167	1.2e-49	162.1	COG0839	NADH:ubiquinone oxidoreductase subunit 6 (chain J)	166
2918748725	181	87.43	22	181	8	160	1.5e-53	174.9	COG1143	Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)	172
2918748726	358	97.6	15	355	5	329	0.0e+00	430.1	COG1005	NADH:ubiquinone oxidoreductase subunit 1 (chain H)	332
2918748727	720	96.72	1	720	1	707	0.0e+00	648.6	COG1034	NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)	693
2918748728	446	94.58	17	438	20	420	0.0e+00	617	COG1894	NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F)	424
2918748729	182	93.37	7	175	10	164	1.6e-51	167.8	COG1905	NADH:ubiquinone oxidoreductase 24 kD subunit (chain E)	160
2918748730	417	97.49	1	417	11	398	0.0e+00	601.2	COG0649	NADH:ubiquinone oxidoreductase 49 kD subunit (chain D)	398
2918748731	203	90	7	187	14	175	1.8e-58	191.3	COG0852	NADH:ubiquinone oxidoreductase 27 kD subunit (chain C)	176
2918748732	159	78.35	1	159	15	166	9.1e-86	279.9	COG0377	NADH:ubiquinone oxidoreductase 20 kD subunit (chhain B) or related Fe-S oxidoreductase	194
2918748733	119	95.9	1	119	5	121	2.6e-49	160.3	COG0838	NADH:ubiquinone oxidoreductase subunit 3 (chain A)	123
2918748735	137	78.49	4	93	3	75	2.3e-27	88.3	COG1314	Preprotein translocase subunit SecG	86
2918748736	254	98.41	2	254	2	249	1.2e-92	303.8	COG0149	Triosephosphate isomerase	251
2918748737	332	99.7	1	332	1	330	2.4e-95	313.6	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2918748738	766	99.57	3	696	2	692	0.0e+00	1044	COG1185	Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase)	692
2918748739	88	96.63	1	88	4	89	2.9e-35	114.2	COG0184	Ribosomal protein S15P/S13E	89
2918748740	386	94.7	3	386	19	393	9.8e-101	331.5	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
2918748741	415	95.36	9	397	9	357	1.5e-41	136.4	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918748742	123	83.56	2	123	19	140	2.5e-16	53.8	COG0071	Molecular chaperone IbpA, HSP20 family	146
2918748743	253	44.07	8	245	91	220	4.8e-06	20.2	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918748744	354	98.84	1	347	1	340	2.6e-129	425	COG0533	tRNA A37 threonylcarbamoyltransferase TsaD	342
2918748747	414	98.21	7	356	4	332	5.3e-74	243.4	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2918748748	283	92.25	21	282	10	247	1.1e-70	231.8	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2918748749	269	98.41	5	265	3	249	3.7e-96	315.3	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2918748750	433	52.17	48	419	31	222	1.1e-01	6	COG0457	Tetratricopeptide (TPR) repeat	291
2918748751	423	95.95	2	407	7	409	1.1e-94	311.4	COG2223	Nitrate/nitrite transporter NarK	417
2918748752	566	8.46	287	374	33	55	2.6e-32	2.9	COG0631	Serine/threonine protein phosphatase PrpC	262
2918748752	566	91.54	2	242	12	260	2.6e-32	101.1	COG0631	Serine/threonine protein phosphatase PrpC	262
2918748753	25	3	2	25	1	24	9.1e-08	24.7	COG1251	NAD(P)H-nitrite reductase, large subunit	793
2918748754	304	97.34	6	297	2	294	7.6e-63	206.9	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918748755	405	46.48	221	397	13	190	8.3e-13	22.5	COG0477	MFS family permease	338
2918748755	405	56.4	24	247	17	232	8.3e-13	23.6	COG0477	MFS family permease	338
2918748756	204	94.25	2	171	2	165	6.8e-42	137.3	COG3576	Predicted flavin-nucleotide-binding protein, pyridoxine 5'-phosphate oxidase superfamily	173
2918748757	622	92.63	104	453	15	303	2.2e-23	76	COG0501	Zn-dependent protease with chaperone function	302
2918748758	405	48.83	209	402	6	192	1.1e-28	9.2	COG0477	MFS family permease	338
2918748758	405	62.92	2	241	8	248	1.1e-28	90.2	COG0477	MFS family permease	338
2918748759	482	51.44	289	481	12	208	1.1e-34	21.9	COG0477	MFS family permease	338
2918748759	482	83.81	29	317	2	322	1.1e-34	95.4	COG0477	MFS family permease	338
2918748760	213	45.22	2	205	220	408	2.7e-43	142.2	COG2995	Uncharacterized paraquat-inducible protein A	418
2918748761	238	48.56	6	223	214	416	3.4e-77	254	COG2995	Uncharacterized paraquat-inducible protein A	418
2918748762	548	97.29	10	548	7	544	0.0e+00	528.3	COG3008	Paraquat-inducible protein B	553
2918748763	210	96.32	1	200	5	187	3.5e-30	99	COG3009	Uncharacterized lipoprotein YmbA	190
2918748764	535	70.76	288	529	9	279	2.9e-43	13.5	COG0477	MFS family permease	338
2918748764	535	83.55	31	328	3	322	2.9e-43	132.6	COG0477	MFS family permease	338
2918748765	688	81.4	50	675	125	671	3.4e-78	257.8	COG1506	Dipeptidyl aminopeptidase/acylaminoacyl peptidase	620
2918748766	234	98.28	17	234	2	229	1.9e-64	211.1	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918748767	457	83.76	116	457	59	388	2.0e-51	169.9	COG0642	Signal transduction histidine kinase	336
2918748768	158	97.35	1	151	3	149	1.2e-51	168.7	COG3865	Glyoxalase superfamily enzyme, possibly 3-demethylubiquinone-9 3-methyltransferase	151
2918748769	471	95.65	9	470	14	453	5.1e-95	312.4	COG0534	Na+-driven multidrug efflux pump	455
2918748770	191	92.78	6	191	6	185	2.2e-66	217.3	COG3644	Uncharacterized protein	194
2918748771	153	90.98	11	141	7	127	1.1e-07	25.8	COG1846	DNA-binding transcriptional regulator, MarR family	126
2918748774	791	98.59	1	789	7	777	0.0e+00	971.6	COG2183	Transcriptional accessory protein Tex/SPT6	780
2918748775	85	65.12	1	79	3	58	9.9e-08	25.7	COG2161	Antitoxin component YafN of the YafNO toxin-antitoxin module, PHD/YefM family	86
2918748776	135	90.91	1	131	2	121	4.8e-29	95.3	COG1487	Predicted nucleic acid-binding protein, contains PIN domain	133
2918748778	327	98.12	7	326	6	318	3.1e-88	289.8	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918748781	370	31.08	108	188	117	194	1.4e-53	48.8	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2918748781	370	37.85	5	117	92	186	1.4e-53	53.1	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2918748781	370	60.96	170	330	52	204	1.4e-53	92.4	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2918748782	881	35.86	640	753	62	151	4.4e-54	35.4	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2918748782	881	52.99	508	688	82	214	4.4e-54	74.7	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2918748782	881	58.96	685	867	54	201	4.4e-54	90.5	COG1357	Uncharacterized protein YjbI, contains pentapeptide repeats	238
2918748784	780	95.33	2	577	11	561	0.0e+00	583.5	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
2918748785	378	99.47	1	378	2	378	4.7e-114	375.1	COG1454	Alcohol dehydrogenase, class IV	377
2918748786	325	94.97	6	324	15	316	4.4e-76	250.4	COG0657	Acetyl esterase/lipase	312
2918748787	292	82.58	165	292	24	151	1.5e-25	83	COG2153	Predicted N-acyltransferase, GNAT family	155
2918748787	292	97.84	9	146	2	137	2.7e-33	108.5	COG0824	Acyl-CoA thioesterase FadM	137
2918748789	308	81.82	5	301	16	267	2.4e-56	185.3	COG0354	Folate-binding Fe-S cluster repair protein YgfZ, possible role in tRNA modification	305
2918748790	340	95.35	1	332	13	340	3.7e-99	325.9	COG1559	Cell division protein YceG, involved in septum cleavage	342
2918748791	219	96.63	2	210	2	202	4.2e-59	193.6	COG0125	Thymidylate kinase	208
2918748793	126	95.73	10	126	6	117	7.9e-42	135.7	COG3215	Tfp pilus assembly protein PilZ	117
2918748794	269	99.22	1	265	2	256	4.3e-88	288.9	COG0084	Tat protein secretion system quality control protein TatD (DNase activity)	256
2918748795	225	46.36	12	116	76	228	2.9e-35	37.2	COG0666	Ankyrin repeat	235
2918748795	225	51.21	75	220	96	264	2.9e-35	84.3	COG0666	Ankyrin repeat	235
2918748796	161	37.98	45	157	53	101	5.6e-06	20.2	COG2852	Very-short-patch-repair endonuclease	129
2918748797	465	18.71	258	293	6	31	1.0e-07	3.9	COG3415	Transposase	138
2918748797	465	82.73	13	144	10	124	1.0e-07	19.8	COG3415	Transposase	138
2918748798	122	41.98	1	121	65	119	2.0e-08	26.4	COG1917	Cupin domain protein related to quercetin dioxygenase	131
2918748799	140	97.81	2	139	4	137	8.2e-47	152.4	COG0432	Thiamin phosphate synthase YjbQ, UPF0047 family	137
2918748800	68	95.77	1	68	1	68	8.5e-31	100.5	COG3360	Flavin-binding protein dodecin	71
2918748801	25	3	2	25	1	24	9.1e-08	24.7	COG1251	NAD(P)H-nitrite reductase, large subunit	793
2918748802	406	94.18	3	400	16	387	4.9e-15	48.7	COG2814	Predicted arabinose efflux permease, MFS family	394
2918748803	191	97.62	16	182	5	168	2.1e-34	113.2	COG0350	O6-methylguanine-DNA--protein-cysteine methyltransferase	168
2918748804	1025	97.87	24	535	8	466	1.8e-87	286.6	COG0277	FAD/FMN-containing dehydrogenase	459
2918748804	1025	98	592	1016	6	398	5.7e-55	180.3	COG0247	Fe-S oxidoreductase	388
2918748805	232	91.81	2	224	14	226	1.5e-58	191.7	COG1802	DNA-binding transcriptional regulator, GntR family	230
2918748806	414	97.65	6	402	8	381	2.8e-101	333	COG0075	Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism protein PucG	383
2918748807	326	96.55	2	323	8	315	4.1e-80	263.1	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918748808	253	15.91	1	53	7	48	2.3e-22	3.5	COG3971	2-keto-4-pentenoate hydratase	264
2918748808	253	60.98	79	253	100	260	2.3e-22	72.3	COG3971	2-keto-4-pentenoate hydratase	264
2918748809	320	96.01	9	302	6	294	1.1e-72	239	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918748810	397	97.22	1	385	10	393	6.2e-128	420.7	COG2814	Predicted arabinose efflux permease, MFS family	394
2918748811	343	98.44	1	326	1	315	3.1e-103	339	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
2918748812	239	98.51	3	219	3	201	9.9e-42	136.4	COG1182	FMN-dependent NADH-azoreductase	202
2918748813	308	97.67	15	308	3	296	6.4e-59	194.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918748814	301	92.54	3	264	2	249	8.3e-45	147.3	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918748815	312	93.49	4	233	1	201	1.8e-26	86.5	COG0625	Glutathione S-transferase	211
2918748816	546	94.24	39	450	18	393	8.2e-73	239.9	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918748817	338	97.35	1	338	8	338	4.0e-130	427.6	COG2130	NADPH-dependent curcumin reductase CurA	340
2918748818	153	89.36	1	137	15	140	2.7e-30	98.9	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
2918748819	264	98.88	10	260	2	266	8.9e-71	232.5	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918748820	100	72.73	1	95	1	72	1.1e-03	12.5	COG1359	Quinol monooxygenase YgiN	100
2918748822	617	97.74	11	486	7	396	9.1e-85	278.4	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2918748823	391	99.75	1	391	1	393	6.1e-120	394.8	COG0183	Acetyl-CoA acetyltransferase	392
2918748824	491	96.17	36	486	12	413	6.4e-70	230	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
2918748825	701	25.53	585	699	188	271	8.5e-113	27.9	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
2918748825	701	89.06	1	284	8	243	9.9e-57	186	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2918748825	701	90.27	297	611	2	298	8.5e-113	341.9	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
2918748826	231	98.73	1	231	3	236	1.9e-85	279.8	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2918748827	258	98.82	2	248	4	254	5.9e-78	255.6	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2918748828	441	95.36	22	337	9	316	7.4e-74	243	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918748829	317	98.34	2	317	3	298	9.8e-81	265.4	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2918748830	412	95.36	10	390	9	357	9.2e-44	143.7	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918748831	409	96.45	7	389	6	358	1.6e-45	149.5	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918748832	59	8.8	1	59	511	560	1.3e-10	34.3	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2918748837	324	97.81	1	323	8	319	9.9e-83	271.8	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918748838	313	95.02	12	312	2	287	2.3e-50	165.9	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918748841	144	88.05	1	135	5	144	1.6e-09	32.6	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2918748842	231	94.92	1	228	8	250	6.1e-50	162.3	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
2918748843	463	81.47	112	463	68	388	1.4e-60	200.1	COG0642	Signal transduction histidine kinase	336
2918748844	224	99.14	1	221	1	230	2.2e-76	250.1	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2918748846	301	96.5	1	299	4	306	4.9e-53	173.4	COG1397	ADP-ribosylglycohydrolase	314
2918748847	358	79.77	6	150	4	141	2.0e-28	93	COG1056	Nicotinamide mononucleotide adenylyltransferase	172
2918748847	358	91.78	202	351	5	138	2.9e-28	91.7	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
2918748848	566	85.97	1	287	2	240	2.6e-47	154.8	COG0388	Predicted amidohydrolase	274
2918748848	566	95.62	275	558	8	269	8.5e-71	232.2	COG0171	NH3-dependent NAD+ synthetase	268
2918748849	395	90	1	394	8	376	1.1e-100	331.1	COG1488	Nicotinic acid phosphoribosyltransferase	405
2918748850	287	95.63	1	285	3	199	2.6e-21	68	COG1335	Nicotinamidase-related amidase	205
2918748851	247	94.52	9	190	6	143	1.8e-35	110.9	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
2918748852	82	95.24	1	82	1	80	1.3e-42	138.2	COG3813	Uncharacterized protein	84
2918748853	187	85.29	3	182	8	152	2.0e-20	67.1	COG0262	Dihydrofolate reductase	167
2918748854	240	99.25	5	239	2	267	7.5e-59	193.4	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918748855	266	97.07	10	247	7	238	1.0e-46	153.2	COG2188	DNA-binding transcriptional regulator, GntR family	236
2918748856	289	88.32	2	281	13	269	2.6e-84	276.7	COG2513	2-Methylisocitrate lyase and related enzymes, PEP mutase family	289
2918748857	466	99.07	1	466	2	426	0.0e+00	512.6	COG0065	Homoaconitase/3-isopropylmalate dehydratase large subunit	423
2918748858	210	95.85	3	202	1	185	8.6e-58	189.2	COG0066	3-isopropylmalate dehydratase small subunit	191
2918748859	327	97.49	10	327	5	315	5.6e-70	229.9	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918748861	244	34.91	118	212	126	199	1.9e-11	16.6	COG0009	tRNA A37 threonylcarbamoyladenosine synthetase subunit TsaC/SUA5/YrdC	211
2918748861	244	35.85	5	87	17	92	1.9e-11	18.8	COG0009	tRNA A37 threonylcarbamoyladenosine synthetase subunit TsaC/SUA5/YrdC	211
2918748862	331	95.92	11	328	11	316	3.0e-77	253.7	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918748865	444	91.3	1	433	31	450	9.2e-56	183.5	COG1538	Outer membrane protein TolC	457
2918748866	730	96.62	18	719	15	701	0.0e+00	646.6	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
2918748867	411	96.15	18	403	14	388	8.0e-41	134.3	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2918748868	147	54.67	7	146	38	119	4.8e-08	26.5	COG2913	Outer membrane protein assembly factor BamE, lipoprotein component of the BamABCDE complex	147
2918748869	316	99.34	2	298	2	300	2.5e-57	188.9	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918748872	492	99.16	8	485	2	476	0.0e+00	598.8	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918748873	325	96.55	5	323	7	314	3.2e-88	289.7	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918748874	355	99.21	4	349	4	379	3.7e-78	253.6	COG1454	Alcohol dehydrogenase, class IV	377
2918748875	417	97.81	8	402	3	360	1.7e-29	96	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2918748876	239	98.43	1	237	4	253	9.8e-75	244.6	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2918748877	238	99.16	2	233	2	236	9.2e-79	257.9	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2918748878	290	97.01	1	290	5	296	3.2e-61	201.5	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2918748879	362	97.52	10	319	8	322	3.8e-68	223.9	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2918748880	288	80.26	50	259	5	187	2.7e-42	138.6	COG3485	Protocatechuate 3,4-dioxygenase beta subunit	226
2918748881	92	14.29	15	80	251	310	7.6e-02	5.9	COG1668	ABC-type Na+ efflux pump, permease component	407
2918748888	109	76.81	17	80	6	58	4.5e-10	32.9	COG1476	DNA-binding transcriptional regulator, XRE-family HTH domain	68
2918748889	448	20.05	43	144	14	93	7.0e-24	3.3	COG3550	Serine/threonine protein kinase HipA, toxin component of the HipAB toxin-antitoxin module	392
2918748889	448	36.59	182	402	179	324	7.0e-24	72.8	COG3550	Serine/threonine protein kinase HipA, toxin component of the HipAB toxin-antitoxin module	392
2918748890	92	59.83	1	81	6	75	1.7e-04	16	COG2963	Transposase and inactivated derivatives	116
2918748891	428	95.99	1	425	12	418	6.5e-93	305.7	COG4949	Uncharacterized membrane-anchored protein	424
2918748894	89	88.37	1	79	5	80	1.6e-06	21.9	COG2161	Antitoxin component YafN of the YafNO toxin-antitoxin module, PHD/YefM family	86
2918748896	337	96.39	9	336	6	325	1.8e-52	172.5	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
2918748898	570	77.11	55	567	65	438	3.9e-78	256.9	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
2918748899	227	98.1	1	221	1	207	1.9e-43	142.4	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2918748900	589	63.19	462	589	10	124	2.2e-07	23.8	COG4567	Two-component response regulator, ActR/RegA family, consists of REC and Fis-type HTH domains	182
2918748900	589	84.26	53	449	59	390	9.5e-57	186.5	COG0642	Signal transduction histidine kinase	336
2918748901	1868	17.25	396	623	461	558	1.5e-23	38.3	COG2303	Choline dehydrogenase or related flavoprotein	542
2918748901	1868	52.64	33	349	6	304	1.5e-23	42.2	COG2303	Choline dehydrogenase or related flavoprotein	542
2918748903	327	97.18	7	325	6	315	2.8e-74	243.9	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918748904	486	93.64	20	479	17	443	6.3e-66	216.7	COG2079	2-methylcitrate dehydratase PrpD	453
2918748905	67	8.8	1	61	511	560	5.4e-11	35.6	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2918748907	142	86.42	1	129	19	158	8.7e-12	39.8	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2918748911	259	94.58	9	254	15	293	6.8e-19	62.1	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918748912	260	98.88	5	257	2	266	4.7e-49	161.2	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918748914	296	97.01	1	296	3	294	1.2e-69	229.3	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918748915	316	99	3	301	1	298	4.6e-55	181.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918748916	486	93.65	2	458	6	462	6.8e-73	240.6	COG3119	Arylsulfatase A or related enzyme	475
2918748917	443	95.74	3	443	18	466	2.1e-102	337.2	COG0277	FAD/FMN-containing dehydrogenase	459
2918748918	327	98.43	1	326	5	318	2.7e-77	254	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918748919	151	69.89	4	147	55	184	1.9e-33	110.1	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
2918748920	149	88.55	14	140	14	129	2.4e-22	73.1	COG1917	Cupin domain protein related to quercetin dioxygenase	131
2918748921	321	98.34	1	318	1	296	1.3e-45	149.9	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918748923	241	90.74	14	233	4	199	8.3e-27	88.2	COG0778	Nitroreductase	207
2918748926	370	65.23	38	367	67	308	7.6e-27	88.1	COG4188	Predicted dienelactone hydrolase	365
2918748927	169	98.25	1	168	3	170	1.3e-49	162.4	COG3153	Predicted N-acetyltransferase YhbS	171
2918748930	117	43.46	8	117	5	107	3.7e-22	73	COG0412	Dienelactone hydrolase	236
2918748931	577	88.65	407	576	9	172	1.1e-39	129.5	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
2918748933	263	98.88	3	249	3	267	6.2e-57	187.1	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2918748934	332	87.88	201	331	9	124	3.9e-19	62.1	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2918748935	52	13.9	4	52	286	331	8.8e-09	29.1	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2918748936	476	98.33	5	474	3	473	0.0e+00	493	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2918748937	340	97.63	46	340	5	292	1.7e-35	117	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2918748938	584	94.98	17	575	27	575	0.0e+00	552.3	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
2918748939	272	67.78	2	205	19	180	7.8e-27	87.5	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
2918748940	266	98.78	7	246	1	243	4.8e-41	134.1	COG1414	DNA-binding transcriptional regulator, IclR family	246
2918748941	330	97.18	10	329	8	317	7.2e-90	295.2	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918748942	323	91.72	5	323	20	318	5.5e-77	252.7	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
2918748944	314	97.01	5	301	5	296	1.8e-52	172.9	COG0583	DNA-binding transcriptional regulator, LysR family	297
2918748946	332	95.92	9	330	10	315	2.6e-67	221	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2918748947	47	5.43	1	33	521	550	5.1e-10	32.3	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
2918748948	100	5.91	1	94	265	314	3.3e-04	13.3	COG1511	Uncharacterized membrane protein YhgE, phage infection protein (PIP) family	780
2918748949	566	81.88	72	520	78	425	3.4e-110	363.3	COG0840	Methyl-accepting chemotaxis protein	408
2918748950	171	90.3	5	170	11	159	1.7e-47	154.9	COG0835	Chemotaxis signal transduction protein	165
2918748951	577	90.35	39	513	42	425	2.9e-119	392.5	COG0840	Methyl-accepting chemotaxis protein	408
2918748952	311	18.12	193	228	9	33	1.8e-01	2.6	COG3105	Uncharacterized membrane-anchored protein YhcB, DUF1043 family	138
2918748952	311	42.75	107	198	56	114	1.8e-01	7.2	COG3105	Uncharacterized membrane-anchored protein YhcB, DUF1043 family	138
2918748953	819	98.75	2	808	1	791	0.0e+00	1135.3	COG1251	NAD(P)H-nitrite reductase, large subunit	793
2918748954	99	79.44	6	99	3	87	2.5e-23	76	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
2918748955	482	95.68	3	163	2	156	4.4e-39	126.4	COG3666	Transposase	161
2918748956	494	73.91	71	494	1	408	0.0e+00	540.4	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
