gene_oid	gene_length	percent_identity	query_start	query_end	subj_start	subj_end	evalue	bit_score	cog_id	cog_name	cog_length
644915202	593	62.46	257	589	79	408	1.0e-126	447	COG0593	Chromosomal replication initiation ATPase DnaA	408
644915203	367	41.58	1	367	1	364	9.0e-90	323	COG0592	DNA polymerase III sliding clamp (beta) subunit, PCNA homolog	364
644915204	378	32.05	4	365	3	362	3.0e-70	259	COG1195	Recombinational DNA repair ATPase RecF	363
644915205	808	63.51	4	558	2	556	0.0e+00	875	COG0187	DNA gyrase/topoisomerase IV, subunit B	635
644915206	236	27.75	58	230	4	156	5.0e-20	91.5	COG1225	Peroxiredoxin	157
644915207	298	30.3	4	294	2	294	7.0e-34	137	COG0583	DNA-binding transcriptional regulator, LysR family	297
644915209	324	29.81	15	324	11	322	1.0e-49	190	COG0598	Mg2+ and Co2+ transporter CorA	322
644915210	1033	31.09	376	713	1	335	1.0e-39	158	COG0642	Signal transduction histidine kinase	336
644915215	203	36.71	1	203	1	207	2.0e-23	102	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
644915218	638	31.38	77	613	2	519	6.0e-101	361	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
644915219	259	24.35	2	191	7	192	1.0e-11	63.8	COG2968	Uncharacterized conserved protein YggE, contains kinase-interacting SIMPL domain	243
644915221	235	31.34	8	220	2	212	1.0e-25	110	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
644915222	686	50.95	3	685	6	691	0.0e+00	806	COG0751	Glycyl-tRNA synthetase, beta subunit	691
644915223	316	74.92	3	297	1	294	0.0e+00	549	COG0752	Glycyl-tRNA synthetase, alpha subunit	298
644915224	294	31.19	1	292	13	307	1.0e-53	203	COG1560	Lauroyl/myristoyl acyltransferase	308
644915229	482	41.33	1	482	1	488	6.0e-92	331	COG0168	Trk-type K+ transport system, membrane component	499
644915230	483	38.96	1	229	1	225	1.0e-46	181	COG0569	Trk K+ transport system, NAD-binding component	225
644915231	433	40.73	90	433	1	355	2.0e-87	316	COG0144	16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family	355
644915232	321	54.7	7	300	3	300	2.0e-112	399	COG0223	Methionyl-tRNA formyltransferase	307
644915233	168	54.17	1	165	1	168	1.0e-56	212	COG0242	Peptide deformylase	168
644915235	389	40.49	9	376	10	349	9.0e-87	314	COG0758	Predicted Rossmann fold nucleotide-binding protein DprA/Smf involved in DNA uptake	350
644915236	168	50.31	4	163	3	161	2.0e-44	171	COG0041	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase	162
644915237	186	37.5	7	186	14	196	4.0e-41	160	COG0009	tRNA A37 threonylcarbamoyladenosine synthetase subunit TsaC/SUA5/YrdC	211
644915238	307	71.1	7	306	4	303	0.0e+00	490	COG0408	Coproporphyrinogen III oxidase	303
644915239	273	39.21	1	273	2	278	2.0e-72	265	COG0169	Shikimate 5-dehydrogenase	283
644915244	522	18.43	233	441	11	219	3.0e-12	67.3	COG0421	Spermidine synthase	282
644915246	265	46.56	1	262	5	266	3.0e-39	155	COG1108	ABC-type Mn2+/Zn2+ transport system, permease component	274
644915247	247	44.84	1	232	4	254	4.0e-70	257	COG1121	ABC-type Mn2+/Zn2+ transport system, ATPase component	254
644915248	160	31.11	25	159	12	143	2.0e-24	105	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
644915249	297	22.08	1	218	9	234	3.0e-20	92.8	COG0803	ABC-type Zn uptake system ZnuABC, Zn-binding component ZnuA	303
644915261	908	59.47	308	908	1	593	0.0e+00	792	COG0749	DNA polymerase I - 3'-5' exonuclease and polymerase domains	593
644915262	111	72.32	2	111	1	112	2.0e-42	163	COG2824	Uncharacterized Zn-ribbon-containing protein	112
644915263	223	23.04	9	204	7	210	5.0e-20	91.4	COG0625	Glutathione S-transferase	211
644915269	447	25.73	9	447	12	450	7.0e-51	195	COG0534	Na+-driven multidrug efflux pump	455
644915270	379	33.71	8	271	1	234	1.0e-52	200	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
644915271	527	52.96	7	525	5	527	0.0e+00	535	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
644915272	206	31.69	5	181	4	184	2.0e-36	145	COG3175	Cytochrome c oxidase assembly protein Cox11	195
644915273	307	32.02	55	307	1	207	2.0e-36	146	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
644915275	243	27.54	4	234	8	241	2.0e-28	119	COG3346	Cytochrome oxidase assembly protein ShyY1	252
644915277	423	25.63	29	419	19	318	4.0e-29	122	COG1612	Heme A synthase	323
644915278	311	49.83	22	308	18	304	7.0e-83	300	COG0109	Polyprenyltransferase (heme O synthase)	304
644915279	221	33.66	19	220	8	207	3.0e-33	135	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
644915283	794	16.54	10	794	35	768	6.0e-17	83.4	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
644915285	287	20.86	38	282	34	310	9.0e-16	77.8	COG0627	S-formylglutathione hydrolase FrmB	316
644915287	733	30.6	4	179	45	224	2.0e-24	107	COG2114	Adenylate cyclase, class 3	227
644915289	733	31.32	4	178	45	223	9.0e-26	112	COG2114	Adenylate cyclase, class 3	227
644915290	179	24.72	2	178	11	187	6.0e-20	90.8	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
644915291	1213	22.68	54	508	2	451	2.0e-47	185	COG0591	Na+/proline symporter	493
644915292	616	36.18	23	614	8	598	9.0e-125	440	COG1164	Oligoendopeptidase F	598
644915293	402	31.51	1	387	4	371	2.0e-76	280	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
644915294	87	43.02	1	86	2	86	5.0e-19	85.8	COG4327	Uncharacterized membrane protein	101
644915295	576	39.08	4	570	7	529	7.0e-127	448	COG4147	Na+(or H+)/acetate symporter ActP	529
644915297	628	35.58	4	624	1	608	2.0e-128	453	COG2905	Signal-transduction protein containing cAMP-binding, CBS, and nucleotidyltransferase domains	610
644915300	224	29.47	6	183	7	193	6.0e-24	104	COG0300	Short-chain dehydrogenase	265
644915301	392	51.04	6	391	1	360	6.0e-127	447	COG1312	D-mannonate dehydratase	362
644915303	494	43.26	1	493	4	496	0.0e+00	530	COG2317	Zn-dependent carboxypeptidase, M32 family	497
644915309	353	47.8	10	191	9	187	2.0e-50	193	COG2169	Methylphosphotriester-DNA--protein-cysteine methyltransferase (N-terminal fragment of Ada), contains Zn-binding and two AraC-type DNA-binding domains	187
644915310	199	19.1	1	199	2	200	1.0e-06	46.6	COG1309	DNA-binding transcriptional regulator, AcrR family	201
644915312	1013	29	5	1006	1	1008	0.0e+00	764	COG0841	Multidrug efflux pump subunit AcrB	1009
644915313	354	30.25	5	350	13	367	6.0e-26	112	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
644915314	204	21.97	1	173	5	175	2.0e-06	46.2	COG1309	DNA-binding transcriptional regulator, AcrR family	201
644915315	191	40.98	1	182	1	182	1.0e-35	142	COG2119	Putative Ca2+/H+ antiporter, TMEM165/GDT1 family	190
644915317	422	27.14	84	413	33	333	6.0e-26	112	COG3866	Pectate lyase	345
644915318	610	31.52	343	599	1	247	6.0e-57	215	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
644915319	1096	33.88	550	851	40	336	1.0e-43	172	COG0642	Signal transduction histidine kinase	336
644915323	446	29.47	43	224	25	214	5.0e-14	72.6	COG0666	Ankyrin repeat	235
644915324	161	29.25	15	160	5	145	4.0e-12	64.3	COG3909	Cytochrome c556	147
644915325	241	37.3	24	207	3	186	2.0e-29	123	COG3658	Cytochrome b	192
644915332	501	33.9	209	500	120	408	2.0e-41	163	COG0840	Methyl-accepting chemotaxis protein	408
644915334	519	28.04	167	482	1	316	2.0e-35	144	COG0668	Small-conductance mechanosensitive channel	316
644915335	560	33.5	168	558	21	406	3.0e-47	183	COG0840	Methyl-accepting chemotaxis protein	408
644915338	257	21.35	7	250	24	279	2.0e-10	59.7	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
644915340	203	32.67	5	203	1	196	1.0e-34	139	COG0288	Carbonic anhydrase	207
644915343	200	33.5	2	198	1	201	2.0e-30	126	COG0625	Glutathione S-transferase	211
644915344	200	28.86	5	197	4	204	9.0e-21	93.8	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
644915346	295	29.77	4	295	2	297	1.0e-30	127	COG0583	DNA-binding transcriptional regulator, LysR family	297
644915347	196	47.29	1	190	1	202	1.0e-58	219	COG1182	FMN-dependent NADH-azoreductase	202
644915348	282	38.43	2	278	5	273	2.0e-56	212	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
644915350	222	22.57	1	222	3	207	4.0e-16	78.5	COG0778	Nitroreductase	207
644915352	310	27.91	1	299	1	289	5.0e-36	145	COG0583	DNA-binding transcriptional regulator, LysR family	297
644915353	234	35	1	212	1	216	1.0e-34	139	COG2045	Phosphosulfolactate phosphohydrolase or related enzyme	230
644915354	415	57.89	3	401	4	390	1.0e-119	423	COG3004	Na+/H+ antiporter NhaA	390
644915355	127	43.75	1	127	1	128	1.0e-31	128	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
644915356	704	42.66	1	701	6	700	0.0e+00	806	COG0317	(p)ppGpp synthase/hydrolase, HD superfamily	701
644915357	93	61.19	1	66	1	67	5.0e-14	69.2	COG1758	DNA-directed RNA polymerase, subunit K/omega	74
644915358	205	51.85	2	190	1	188	1.0e-69	255	COG0194	Guanylate kinase	191
644915359	288	46.9	1	288	1	290	1.0e-78	286	COG1561	Uncharacterized conserved protein YicC, UPF0701 family	290
644915360	239	59.49	2	237	8	229	4.0e-76	277	COG0689	Ribonuclease PH	230
644915362	272	52.21	1	271	1	272	1.0e-95	342	COG0266	Formamidopyrimidine-DNA glycosylase	273
644915364	51	55.1	1	49	2	50	5.0e-10	56	COG0267	Ribosomal protein L33	50
644915365	78	59.74	1	76	1	77	2.0e-20	90.7	COG0227	Ribosomal protein L28	77
644915367	224	50.89	1	224	1	224	4.0e-76	277	COG2003	DNA repair protein RadC, contains a helix-hairpin-helix DNA-binding motif	224
644915368	409	53.03	9	403	1	391	4.0e-112	398	COG0452	Phosphopantothenoylcysteine synthetase/decarboxylase	392
644915369	845	35.7	385	837	4	464	6.0e-97	349	COG1109	Phosphomannomutase	464
644915370	308	49.64	30	305	2	265	2.0e-82	299	COG0548	Acetylglutamate kinase	265
644915371	197	22.03	1	177	5	179	1.0e-08	53.5	COG1309	DNA-binding transcriptional regulator, AcrR family	201
644915373	213	37.26	3	210	1	201	7.0e-44	170	COG0461	Orotate phosphoribosyltransferase	201
644915374	257	30.3	1	254	1	261	2.0e-51	196	COG0708	Exonuclease III	261
644915375	465	60.57	6	464	1	459	0.0e+00	655	COG0165	Argininosuccinate lyase	459
644915377	243	38.02	1	240	2	241	5.0e-44	171	COG3279	DNA-binding response regulator, LytR/AlgR family	244
644915378	324	58.17	15	319	1	306	2.0e-115	408	COG0181	Porphobilinogen deaminase	307
644915379	266	26.1	7	254	2	241	2.0e-29	122	COG1587	Uroporphyrinogen-III synthase	248
644915380	421	30	39	405	2	356	1.0e-40	160	COG2959	Uncharacterized conserved protein HemX (no evidence of involvement in heme biosynthesis)	391
644915381	401	32.57	1	391	1	389	7.0e-61	228	COG3071	Uncharacterized conserved protein HemY, contains two TPR repeats	400
644915382	233	32.58	5	221	4	223	5.0e-33	134	COG0300	Short-chain dehydrogenase	265
644915385	183	23.89	5	180	3	179	4.0e-08	51.2	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
644915386	1022	28.96	664	1019	65	418	5.0e-37	150	COG4995	Uncharacterized conserved protein, contains CHAT domain	420
644915388	185	35.71	13	68	5	60	1.0e-07	50.2	COG1476	DNA-binding transcriptional regulator, XRE-family HTH domain	68
644915389	474	33.33	293	474	2	180	1.0e-37	151	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
644915390	486	61.32	1	486	2	475	0.0e+00	680	COG0043	3-polyprenyl-4-hydroxybenzoate decarboxylase	477
644915391	419	74.22	1	419	4	421	0.0e+00	701	COG1158	Transcription termination factor Rho	422
644915393	711	51.9	22	703	2	683	0.0e+00	882	COG0855	Polyphosphate kinase	696
644915394	781	30.14	148	491	2	327	3.0e-44	173	COG0642	Signal transduction histidine kinase	336
644915395	388	42.86	11	388	34	412	1.0e-105	376	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
644915397	203	47	3	201	2	192	2.0e-64	238	COG0127	Inosine/xanthosine triphosphate pyrophosphatase, all-alpha NTP-PPase family	194
644915400	383	46.9	9	379	10	368	4.0e-121	428	COG2021	Homoserine acetyltransferase	368
644915401	99	49.45	8	96	9	96	1.0e-20	91.5	COG1872	Uncharacterized conserved protein YggU, UPF0235/DUF167 family	102
644915403	277	45.35	7	274	3	266	5.0e-71	261	COG0345	Pyrroline-5-carboxylate reductase	266
644915404	228	50.22	4	227	3	227	3.0e-69	254	COG0325	Uncharacterized pyridoxal phosphate-containing protein, affects Ilv metabolism, UPF0001 family	228
644915405	344	66.96	1	344	3	347	0.0e+00	546	COG2805	Tfp pilus assembly protein PilT, pilus retraction ATPase	353
644915406	380	68.73	1	371	5	375	0.0e+00	587	COG5008	Tfp pilus assembly protein, ATPase PilU	375
644915407	146	43.48	9	145	3	140	1.0e-36	145	COG0816	RNase H-fold protein, predicted Holliday junction resolvase in Firmicutes and mycoplasms, involved in anti-termination at Rho-dependent terminators	141
644915408	192	47.42	1	192	1	194	5.0e-63	233	COG1678	Putative transcriptional regulator, AlgH/UPF0301 family	194
644915410	319	40.43	5	316	1	315	4.0e-74	271	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
644915413	179	18.63	17	177	2	161	5.0e-21	94.2	COG0835	Chemotaxis signal transduction protein	165
644915414	733	31.84	269	669	10	408	8.0e-45	175	COG0840	Methyl-accepting chemotaxis protein	408
644915415	285	30.74	13	268	1	252	2.0e-56	213	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
644915416	2283	31.8	1469	2131	2	707	3.0e-125	444	COG0643	Chemotaxis protein histidine kinase CheA	716
644915419	290	41.03	1	284	3	286	1.0e-71	263	COG1281	Redox-regulated molecular chaperone, HSP33 family	286
644915420	130	57.78	2	91	7	96	2.0e-22	98.1	COG1188	Ribosomal 50S subunit-recycling heat shock protein, contains S4 domain	100
644915421	217	21.08	4	214	1	222	9.0e-17	80.3	COG1011	FMN phosphatase YigB, HAD superfamily	229
644915422	180	32.58	46	175	12	140	1.0e-06	46.2	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
644915423	274	46.35	4	273	6	273	1.0e-71	262	COG1218	3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase	276
644915425	961	30.86	16	862	1	841	0.0e+00	552	COG3072	Adenylate cyclase	853
644915426	162	59.49	1	158	2	159	2.0e-60	225	COG0669	Phosphopantetheine adenylyltransferase	159
644915427	191	44.02	12	189	1	184	8.0e-52	196	COG0742	16S rRNA G966 N2-methylase RsmD	187
644915428	334	55.33	2	332	3	340	2.0e-111	395	COG0552	Signal recognition particle GTPase	340
644915429	225	58.26	1	218	1	218	3.0e-84	304	COG2884	ABC-type ATPase involved in cell division	223
644915430	324	35.43	23	324	1	297	7.0e-56	211	COG2177	Cell division protein FtsX	297
644915431	284	34.98	8	284	60	333	2.0e-62	232	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
644915432	156	47.11	36	156	3	121	2.0e-23	101	COG2363	Uncharacterized membrane protein YgdD, TMEM256/DUF423 family	124
644915433	229	42.67	8	229	2	226	3.0e-61	228	COG0220	tRNA G46 methylase TrmB	227
644915436	253	38.97	28	240	3	205	7.0e-46	177	COG0545	FKBP-type peptidyl-prolyl cis-trans isomerase	205
644915438	154	33.12	1	154	1	159	7.0e-32	130	COG3160	Regulator of sigma D	162
644915439	139	25	19	138	44	159	1.0e-17	82.2	COG1580	Flagellar basal body-associated protein FliL	159
644915440	536	45.42	4	524	2	517	0.0e+00	503	COG2918	Gamma-glutamylcysteine synthetase	518
644915441	330	21.84	35	326	14	275	2.0e-25	110	COG3031	Type II secretory pathway, component PulC	275
644915442	661	31.71	28	635	32	583	8.0e-96	345	COG1450	Type II secretory pathway component GspD/PulD (secretin)	587
644915443	514	52.05	31	511	14	498	0.0e+00	551	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
644915444	410	41.22	1	410	1	397	2.0e-96	346	COG1459	Type II secretory pathway, component PulF	397
644915445	149	37.58	1	141	1	149	2.0e-20	91.7	COG2165	Type II secretory pathway, pseudopilin PulG	149
644915448	230	27.83	13	223	4	189	1.0e-15	77	COG4795	Type II secretory pathway, component PulJ	194
644915449	348	31.47	5	343	4	315	2.0e-42	166	COG3156	Type II secretory pathway, component PulK	323
644915450	410	22.08	24	404	26	387	4.0e-27	115	COG3297	Type II secretory pathway, component PulL	390
644915451	159	25.32	4	156	24	176	6.0e-13	67	COG3149	Type II secretory pathway, component PulM	181
644915453	333	34.74	4	327	8	329	2.0e-63	236	COG1477	Thiamine biosynthesis lipoprotein ApbE	337
644915457	608	31.46	245	608	39	436	2.0e-51	197	COG3325	Chitinase, GH18 family	441
644915464	770	29.33	260	758	174	644	2.0e-67	251	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
644915466	143	23.28	25	136	5	119	1.0e-07	48.7	COG2346	Truncated hemoglobin YjbI	133
644915467	346	22.1	3	336	2	346	6.0e-23	101	COG4663	TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component	363
644915468	440	31.99	1	439	2	447	5.0e-64	238	COG4664	TRAP-type mannitol/chloroaromatic compound transport system, large permease component	447
644915469	201	28.85	45	198	11	166	2.0e-21	95.3	COG4665	TRAP-type mannitol/chloroaromatic compound transport system, small permease component	182
644915470	272	42.45	8	252	64	294	2.0e-64	239	COG4302	Ethanolamine ammonia-lyase, small subunit	294
644915471	527	56.61	53	506	1	452	0.0e+00	670	COG4303	Ethanolamine ammonia-lyase, large subunit	453
644915472	413	25.86	5	409	1	381	3.0e-43	169	COG5505	Uncharacterized membrane protein	384
644915475	148	25.66	2	144	1	147	2.0e-11	62	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
644915476	121	34.45	1	119	1	119	2.0e-27	114	COG1733	DNA-binding transcriptional regulator, HxlR family	120
644915477	374	39.11	11	364	6	341	1.0e-82	300	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
644915479	220	28.47	57	193	25	142	1.0e-14	73.4	COG0262	Dihydrofolate reductase	167
644915482	135	28.36	8	134	7	130	6.0e-10	56.8	COG3607	Predicted lactoylglutathione lyase	133
644915483	696	25.86	80	648	11	488	1.0e-58	221	COG0737	2',3'-cyclic-nucleotide 2'-phosphodiesterase/5'- or 3'-nucleotidase, 5'-nucleotidase family	517
644915486	258	26.95	1	256	1	279	2.0e-24	105	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
644915487	334	39.6	1	329	1	339	5.0e-61	228	COG1294	Cytochrome bd-type quinol oxidase, subunit 2	346
644915488	454	45.59	1	444	1	454	7.0e-127	447	COG1271	Cytochrome bd-type quinol oxidase, subunit 1	457
644915489	184	37.85	1	177	2	176	2.0e-33	135	COG1510	DNA-binding transcriptional regulator GbsR, MarR family	177
644915501	724	40.21	253	723	105	544	4.0e-114	405	COG2225	Malate synthase	545
644915502	532	26.68	18	531	17	433	4.0e-108	385	COG2224	Isocitrate lyase	433
644915503	232	38.37	1	232	1	244	6.0e-47	180	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
644915504	195	37.57	1	187	1	177	3.0e-27	115	COG0431	NAD(P)H-dependent FMN reductase	184
644915506	307	32.45	10	291	2	299	1.0e-45	177	COG1397	ADP-ribosylglycohydrolase	314
644915512	448	25.23	9	440	19	447	2.0e-45	176	COG0534	Na+-driven multidrug efflux pump	455
644915513	198	31.53	2	194	1	189	6.0e-26	110	COG2249	Putative NADPH-quinone reductase (modulator of drug activity B)	189
644915514	305	37.66	1	300	1	307	1.0e-71	263	COG0039	Malate/lactate dehydrogenase	313
644915516	88	47.13	1	87	1	87	5.0e-29	119	COG2924	Fe-S cluster biosynthesis and repair protein YggX	90
644915517	352	47.55	1	346	8	342	1.0e-109	389	COG1194	Adenine-specific DNA glycosylase, acts on AG and A-oxoG pairs	342
644915518	363	46.13	1	361	4	375	2.0e-105	375	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
644915519	130	57.69	1	129	2	131	4.0e-39	153	COG0509	Glycine cleavage system H protein (lipoate-binding)	131
644915520	291	28.72	4	289	7	289	9.0e-46	177	COG1639	HD-like signal output (HDOD) domain, no enzymatic activity	289
644915522	217	34.27	1	213	5	202	4.0e-41	161	COG0560	Phosphoserine phosphatase	212
644915523	171	20.57	13	152	17	151	4.0e-11	61.2	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
644915524	753	48.01	1	748	1	754	0.0e+00	826	COG3605	Signal transduction protein containing GAF and PtsI domains	756
644915525	286	42.23	1	275	5	287	1.0e-59	223	COG0682	Prolipoprotein diacylglyceryltransferase	287
644915526	277	65.23	1	277	3	268	3.0e-116	411	COG0207	Thymidylate synthase	268
644915527	173	48.26	9	173	2	167	1.0e-45	175	COG0262	Dihydrofolate reductase	167
644915531	133	29.37	8	132	10	134	2.0e-18	84.9	COG0848	Biopolymer transport protein ExbD	137
644915534	612	53.33	1	610	8	575	0.0e+00	787	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
644915537	441	33.83	23	289	1	265	1.0e-52	201	COG0548	Acetylglutamate kinase	265
644915538	388	33	7	381	15	407	1.0e-61	230	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
644915539	267	34.71	1	267	2	291	2.0e-55	209	COG0384	Predicted epimerase YddE/YHI9, PhzF superfamily	291
644915540	592	42.45	95	588	14	500	0.0e+00	492	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
644915542	761	61.69	23	758	11	753	0.0e+00	985	COG1882	Pyruvate-formate lyase	755
644915543	184	22.11	6	175	5	190	4.0e-20	91.1	COG1057	Nicotinic acid mononucleotide adenylyltransferase	197
644915544	567	32.21	277	567	6	303	2.0e-45	177	COG0668	Small-conductance mechanosensitive channel	316
644915549	430	21.25	73	359	9	225	1.0e-12	67.9	COG0584	Glycerophosphoryl diester phosphodiesterase	257
644915550	504	51.61	5	341	8	347	3.0e-118	419	COG1171	Threonine dehydratase	347
644915551	225	53.68	1	223	1	227	1.0e-74	272	COG0120	Ribose 5-phosphate isomerase	227
644915552	411	43.37	10	338	1	324	2.0e-87	316	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
644915554	78	32	4	78	2	75	2.0e-09	54	COG1918	Fe2+ transport system protein FeoA	75
644915556	185	36.17	1	185	3	190	1.0e-39	155	COG0212	5-formyltetrahydrofolate cyclo-ligase	191
644915558	95	38.2	6	94	2	89	3.0e-13	66.5	COG3027	Cell division protein ZapA, inhibits GTPase activity of FtsZ	105
644915560	201	34.44	2	181	3	172	3.0e-17	81.9	COG3079	Uncharacterized conserved protein YgfB, UPF0149 family	186
644915561	443	32.15	15	432	3	384	6.0e-74	271	COG0006	Xaa-Pro aminopeptidase	384
644915562	427	34.65	9	409	1	384	7.0e-62	231	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
644915563	419	34.47	7	415	2	384	5.0e-67	248	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
644915564	425	33.66	22	425	19	415	1.0e-75	277	COG2995	Uncharacterized paraquat-inducible protein A	418
644915565	536	36.36	8	535	12	543	7.0e-113	401	COG3008	Paraquat-inducible protein B	553
644915566	207	25.26	9	196	5	188	6.0e-15	74.2	COG3009	Uncharacterized lipoprotein YmbA	190
644915573	430	29.68	26	426	2	378	1.0e-40	160	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
644915576	197	57.87	1	197	1	195	1.0e-80	292	COG0131	Imidazoleglycerol phosphate dehydratase HisB	195
644915577	225	47.27	4	223	2	204	4.0e-72	264	COG0118	Imidazoleglycerol phosphate synthase glutamine amidotransferase subunit HisH	204
644915578	245	49.38	1	241	2	239	6.0e-79	287	COG0106	Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase	241
644915579	257	69.41	3	257	2	255	1.0e-113	402	COG0107	Imidazole glycerol phosphate synthase subunit HisF	256
644915581	226	33.33	5	226	1	216	2.0e-37	148	COG1392	Uncharacterized conserved protein YkaA, distantly related to PhoU, UPF0111/DUF47 family	217
644915582	257	37.07	30	257	10	237	2.0e-34	139	COG4798	Predicted methyltransferase	238
644915583	699	20.21	300	672	72	375	4.0e-12	67.4	COG2730	Aryl-phospho-beta-D-glucosidase BglC, GH1 family	407
644915584	894	20.31	495	867	72	375	9.0e-11	62.8	COG2730	Aryl-phospho-beta-D-glucosidase BglC, GH1 family	407
644915587	194	27.46	6	135	1	134	8.0e-11	60.3	COG1225	Peroxiredoxin	157
644915590	208	49.29	2	208	4	213	2.0e-52	198	COG3132	Uncharacterized conserved protein YceH, UPF0502 family	215
644915592	602	40.03	15	594	1	565	0.0e+00	464	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
644915595	200	45.11	13	195	18	200	4.0e-22	98.1	COG2370	Hydrogenase/urease accessory protein HupE	201
644915601	181	48.89	1	180	2	162	1.0e-57	215	COG0386	Glutathione peroxidase, house-cleaning role in reducing lipid peroxides	162
644915602	398	27.41	25	293	24	274	9.0e-28	118	COG3509	Poly(3-hydroxybutyrate) depolymerase	312
644915607	309	58.62	23	279	10	270	2.0e-98	352	COG2326	Polyphosphate kinase 2, PPK2 family	270
644915608	280	36.69	1	277	7	312	3.0e-67	248	COG0627	S-formylglutathione hydrolase FrmB	316
644915609	368	67.93	1	368	1	366	0.0e+00	567	COG1062	Zn-dependent alcohol dehydrogenase	366
644915610	591	16.99	128	591	69	460	2.0e-24	107	COG0471	Di- and tricarboxylate transporter	461
644915612	565	48.41	48	548	6	503	0.0e+00	500	COG1292	Choline-glycine betaine transporter	537
644915613	383	30.97	263	375	23	127	1.0e-12	68	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
644915616	369	29.09	1	150	9	173	6.0e-17	82	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
644915617	482	28.71	172	477	15	318	2.0e-49	190	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
644915621	1033	34.9	572	1033	29	481	3.0e-75	277	COG3488	Uncharacterized conserved protein with two CxxC motifs, DUF1111 family	481
644915622	332	34.34	1	332	1	329	1.0e-67	250	COG0460	Homoserine dehydrogenase	333
644915623	512	45.21	2	511	28	546	0.0e+00	468	COG3604	Transcriptional regulator containing GAF, AAA-type ATPase, and DNA-binding Fis domains	550
644915624	395	52	1	150	1	150	9.0e-52	197	COG1017	Hemoglobin-like flavoprotein	150
644915625	208	26.67	23	202	17	175	1.0e-23	103	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
644915629	247	45.53	1	247	1	249	8.0e-72	263	COG4422	Bacteriophage protein gp37	250
644915631	619	48.75	262	618	1	342	3.0e-95	343	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
644915632	640	47.81	3	435	1	421	2.0e-117	416	COG0358	DNA primase (bacterial type)	568
644915633	201	26.13	1	190	1	196	8.0e-16	77.2	COG0625	Glutathione S-transferase	211
644915634	484	68.42	3	476	2	473	0.0e+00	807	COG0362	6-phosphogluconate dehydrogenase	473
644915635	131	42.74	1	117	1	112	5.0e-29	119	COG2315	Predicted DNA-binding protein with ?double-wing? structural motif, MmcQ/YjbR family	118
644915636	325	30.93	1	323	3	329	2.0e-54	206	COG2334	Ser/Thr protein kinase RdoA involved in Cpx stress response, MazF antagonist	331
644915637	554	27.61	366	528	1	161	1.0e-20	95.2	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
644915639	234	39.17	20	233	11	225	7.0e-40	157	COG1040	Predicted amidophosphoribosyltransferases	225
644915640	351	59.5	9	327	11	329	1.0e-122	432	COG0502	Biotin synthase or related enzyme	335
644915641	395	48.84	1	384	1	387	7.0e-126	444	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
644915642	570	25.76	291	493	5	224	5.0e-23	103	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
644915643	233	43.72	1	231	2	223	2.0e-58	219	COG0132	Dethiobiotin synthetase	223
644915648	591	31.22	38	456	8	387	1.0e-63	237	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
644915650	155	53.33	3	151	2	150	9.0e-49	185	COG2947	Predicted RNA-binding protein, contains PUA-like domain	156
644915652	228	30.05	13	224	16	226	6.0e-27	114	COG1802	DNA-binding transcriptional regulator, GntR family	230
644915655	325	36.21	4	288	2	301	1.0e-50	194	COG4569	Acetaldehyde dehydrogenase (acetylating)	310
644915663	1149	32.83	32	354	9	335	8.0e-62	232	COG3693	Endo-1,4-beta-xylanase, GH35 family	345
644915664	444	37.22	263	437	1	180	1.0e-40	161	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
644915673	298	29.96	43	290	26	276	2.0e-32	133	COG3386	Sugar lactone lactonase YvrE	307
644915688	860	46.07	23	743	2	703	0.0e+00	723	COG0557	Exoribonuclease R	706
644915689	247	43.72	2	247	20	260	4.0e-61	228	COG0566	tRNA G18 (ribose-2'-O)-methylase SpoU	260
644915690	151	43.75	2	112	1	112	4.0e-29	120	COG0360	Ribosomal protein S6	112
644915691	75	72.06	1	68	8	75	3.0e-22	96.4	COG0238	Ribosomal protein S18	75
644915693	149	46.31	1	149	1	147	3.0e-35	141	COG0359	Ribosomal protein L9	148
644915694	442	48.74	1	435	3	434	0.0e+00	512	COG0305	Replicative DNA helicase	435
644915696	285	51.93	1	283	1	285	1.0e-102	366	COG0414	Panthothenate synthetase	285
644915697	126	53.6	2	126	1	125	2.0e-43	168	COG0853	Aspartate 1-decarboxylase	126
644915698	646	43.53	67	621	1	525	0.0e+00	656	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
644915699	154	51.61	1	154	1	154	8.0e-41	159	COG1047	FKBP-type peptidyl-prolyl cis-trans isomerase 2	174
644915700	463	28.14	146	342	4	196	3.0e-38	153	COG1611	Predicted Rossmann fold nucleotide-binding protein	205
644915701	191	40.94	34	178	36	184	8.0e-31	126	COG2840	DNA-nicking endonuclease, Smr domain	184
644915702	137	23.88	1	134	6	133	6.0e-11	60	COG5331	Uncharacterized protein	139
644915705	613	56.96	11	612	1	625	0.0e+00	814	COG1154	Deoxyxylulose-5-phosphate synthase	627
644915706	878	45.94	6	878	7	910	0.0e+00	928	COG2352	Phosphoenolpyruvate carboxylase	910
644915707	320	19.85	88	307	24	281	3.0e-09	56.2	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
644915708	272	54.17	12	272	1	264	7.0e-93	333	COG0413	Ketopantoate hydroxymethyltransferase	268
644915709	228	32.52	18	214	5	210	3.0e-37	148	COG1428	Deoxyadenosine/deoxycytidine kinase	216
644915710	160	52.23	1	156	2	158	2.0e-47	181	COG0801	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase	160
644915711	463	37.91	35	449	1	412	1.0e-80	294	COG0617	tRNA nucleotidyltransferase/poly(A) polymerase	412
644915712	480	43.52	12	478	2	462	0.0e+00	469	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
644915716	146	53.85	27	143	1	117	1.0e-28	118	COG1734	RNA polymerase-binding transcription factor DksA	120
644915718	233	53.62	1	233	1	230	4.0e-69	254	COG1489	DNA-binding protein, stimulates sugar fermentation	235
644915719	105	34.62	3	105	6	104	1.0e-16	78.5	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
644915721	225	28.11	7	184	29	210	1.0e-20	93.6	COG1876	LD-carboxypeptidase LdcB, LAS superfamily	241
644915722	216	34.68	2	215	4	220	8.0e-34	137	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
644915725	182	54.29	1	175	1	171	2.0e-55	208	COG0221	Inorganic pyrophosphatase	171
644915726	975	36.06	296	562	81	335	5.0e-36	147	COG0642	Signal transduction histidine kinase	336
644915728	477	37.83	18	466	9	457	3.0e-125	442	COG0773	UDP-N-acetylmuramate-alanine ligase	459
644915729	209	45.5	5	204	1	188	4.0e-61	227	COG0163	3-polyprenyl-4-hydroxybenzoate decarboxylase	191
644915731	862	22.26	1	853	1	723	4.0e-79	289	COG1033	Predicted exporter protein, RND superfamily	727
644915733	446	26.59	129	446	2	329	8.0e-31	128	COG0642	Signal transduction histidine kinase	336
644915734	225	43.04	1	224	1	229	8.0e-60	223	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
644915736	181	32.41	28	172	33	167	2.0e-14	71.9	COG3134	Uncharacterized conserved protein YcfJ, contains glycine zipper 2TM domain	179
644915737	218	31.75	3	208	2	210	3.0e-32	132	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
644915738	230	33.33	79	222	1	161	5.0e-19	88.1	COG4067	Uncharacterized conserved protein	162
644915741	418	57.59	3	416	1	415	0.0e+00	585	COG0014	Gamma-glutamyl phosphate reductase	417
644915742	118	51.4	4	110	5	111	1.0e-31	128	COG0799	Ribosomal silencing factor RsfS, regulates association of 30S and 50S subunits	115
644915743	158	45.57	1	158	1	155	6.0e-49	186	COG1576	23S rRNA pseudoU1915 N3-methylase RlmH	155
644915744	623	34.39	10	618	2	594	0.0e+00	474	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
644915745	382	43.36	25	381	9	376	2.0e-80	292	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
644915746	329	35.25	30	323	46	338	1.0e-73	270	COG2951	Membrane-bound lytic murein transglycosylase B	343
644915747	289	37.14	8	214	7	216	8.0e-46	177	COG0797	Rare lipoprotein A, peptidoglycan hydrolase digesting "naked" glycans, contains C-terminal SPOR domain	233
644915749	390	44.79	8	388	7	385	1.0e-108	386	COG1686	D-alanyl-D-alanine carboxypeptidase	389
644915750	90	44.05	7	90	8	90	5.0e-20	89.2	COG2921	Putative lipoic acid-binding regulatory protein	90
644915751	204	55.83	1	204	8	211	3.0e-73	268	COG0321	Lipoate-protein ligase B	221
644915752	326	64.82	21	326	1	306	0.0e+00	490	COG0320	Lipoate synthase	306
644915754	439	35.4	1	439	1	436	0.0e+00	463	COG0621	tRNA A37 methylthiotransferase MiaB	437
644915759	290	29.04	5	271	3	254	3.0e-27	115	COG0388	Predicted amidohydrolase	274
644915761	897	39.06	6	635	1	598	2.0e-122	434	COG1042	Acyl-CoA synthetase (NDP forming)	598
644915763	362	42.86	195	359	1	168	4.0e-44	172	COG0350	O6-methylguanine-DNA--protein-cysteine methyltransferase	168
644915765	487	32.56	20	485	6	460	1.0e-50	194	COG0471	Di- and tricarboxylate transporter	461
644915772	320	53.24	1	319	1	340	7.0e-110	390	COG0205	6-phosphofructokinase	347
644915776	321	35.12	26	321	13	307	1.0e-60	227	COG1560	Lauroyl/myristoyl acyltransferase	308
644915777	573	28.7	92	427	9	334	5.0e-40	159	COG0642	Signal transduction histidine kinase	336
644915778	854	37.26	12	847	47	844	0.0e+00	644	COG1643	HrpA-like RNA helicase	845
644915781	601	50.42	1	597	1	587	0.0e+00	707	COG0514	Superfamily II DNA helicase RecQ	590
644915782	305	45.51	8	305	6	298	2.0e-94	339	COG4989	Predicted oxidoreductase	298
644915784	161	38.89	1	161	1	161	1.0e-31	129	COG1047	FKBP-type peptidyl-prolyl cis-trans isomerase 2	174
644915786	290	33.07	157	283	1	127	1.0e-20	93.8	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
644915787	519	29.02	61	508	11	452	1.0e-54	207	COG0534	Na+-driven multidrug efflux pump	455
644915791	331	59.39	1	329	1	328	0.0e+00	494	COG0113	Delta-aminolevulinic acid dehydratase, porphobilinogen synthase	330
644915792	552	32.37	62	537	55	473	2.0e-78	287	COG1785	Alkaline phosphatase	482
644915795	402	56.4	186	395	2	212	6.0e-59	221	COG0560	Phosphoserine phosphatase	212
644915796	698	28.22	446	686	1	239	6.0e-39	156	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
644915798	335	47.31	2	334	4	337	2.0e-106	379	COG1509	L-lysine 2,3-aminomutase (EF-P beta-lysylation pathway)	369
644915799	189	48.09	1	131	1	131	1.0e-41	162	COG0231	Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)	131
644915800	322	46.52	2	315	6	317	9.0e-86	310	COG2269	Elongation factor P--beta-lysine ligase (EF-P beta-lysylation pathway)	322
644915801	269	58.66	86	264	7	185	9.0e-64	237	COG1045	Serine acetyltransferase	194
644915803	237	33.02	22	236	16	229	6.0e-39	154	COG1802	DNA-binding transcriptional regulator, GntR family	230
644915806	916	19.14	135	734	41	618	1.0e-51	198	COG3250	Beta-galactosidase/beta-glucuronidase	808
644915808	332	33.04	2	332	3	331	6.0e-55	207	COG3380	Predicted NAD/FAD-dependent oxidoreductase	331
644915809	447	32.94	12	425	5	412	4.0e-79	289	COG0415	Deoxyribodipyrimidine photolyase	461
644915812	228	36.05	4	222	1	226	2.0e-39	155	COG2135	Putative SOS response-associated peptidase YedK	226
644915813	374	51.47	1	372	1	368	8.0e-117	413	COG2377	1,6-Anhydro-N-acetylmuramate kinase	371
644915814	426	36.59	191	391	72	273	2.0e-33	137	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
644915815	432	44.96	5	429	2	397	4.0e-115	408	COG0162	Tyrosyl-tRNA synthetase	401
644915816	439	39.77	261	432	6	181	2.0e-40	160	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
644915819	287	14.56	41	243	65	267	2.0e-06	46.5	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
644915823	341	25.33	56	338	87	380	1.0e-21	97.8	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
644915824	352	25.43	9	351	54	377	3.0e-33	136	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
644915825	307	41.97	6	306	6	307	4.0e-73	268	COG1560	Lauroyl/myristoyl acyltransferase	308
644915828	362	28.61	12	353	2	332	1.0e-49	191	COG0859	ADP-heptose:LPS heptosyltransferase	334
644915831	289	21.4	12	275	3	248	1.0e-10	60.7	COG3713	Outer membrane scaffolding protein for murein synthesis, MipA/OmpV family	258
644915833	527	68.88	3	527	2	528	0.0e+00	862	COG4108	Peptide chain release factor RF-3	528
644915834	204	25	11	192	22	219	3.0e-15	75.3	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
644915835	357	29.91	7	338	13	353	1.0e-31	131	COG0628	Predicted PurR-regulated permease PerM	355
644915836	473	37.36	5	455	3	454	5.0e-109	388	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
644915837	291	20.21	19	291	12	289	2.0e-22	99.6	COG1639	HD-like signal output (HDOD) domain, no enzymatic activity	289
644915840	403	26.05	193	401	33	244	6.0e-15	75.6	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
644915843	223	19.46	1	212	1	221	5.0e-06	44.9	COG5581	c-di-GMP-binding flagellar brake protein YcgR, contains PilZNR and PilZ domains	233
644915846	360	37.46	6	343	1	342	2.0e-79	289	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
644915849	138	30.6	1	134	1	131	6.0e-20	89.9	COG0848	Biopolymer transport protein ExbD	137
644915852	961	59.96	476	933	31	496	0.0e+00	701	COG1003	Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain	496
644915857	453	34.52	118	452	10	339	9.0e-95	341	COG0208	Ribonucleotide reductase beta subunit, ferritin-like domain	348
644915858	961	35.28	185	926	1	652	0.0e+00	574	COG0209	Ribonucleotide reductase alpha subunit	696
644915860	304	57.14	1	300	4	309	1.0e-118	419	COG0078	Ornithine carbamoyltransferase	310
644915861	386	48.84	1	386	12	398	0.0e+00	491	COG4992	Acetylornithine/succinyldiaminopimelate/putrescine aminotransferase	404
644915862	111	60.58	1	103	2	105	3.0e-41	159	COG0278	Glutaredoxin-related protein	105
644915863	379	37.7	65	375	53	338	1.0e-66	247	COG3693	Endo-1,4-beta-xylanase, GH35 family	345
644915868	292	29.87	1	292	11	308	3.0e-40	158	COG1305	Transglutaminase-like enzyme, putative cysteine protease	319
644915869	842	44.47	5	481	3	480	0.0e+00	514	COG2308	Uncharacterized conserved protein, circularly permuted ATPgrasp superfamily	488
644915873	264	32.27	5	243	3	234	8.0e-39	154	COG1387	Histidinol phosphatase or related hydrolase of the PHP family	237
644915877	614	29.82	114	603	170	651	2.0e-84	306	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
644915881	1535	55.02	712	1205	1	485	0.0e+00	643	COG0069	Glutamate synthase domain 2	485
644915882	490	43.52	23	488	2	450	0.0e+00	465	COG0493	NADPH-dependent glutamate synthase beta chain or related oxidoreductase	457
644915884	456	33.79	25	453	7	427	4.0e-61	229	COG5520	O-Glycosyl hydrolase	433
644915885	405	38.4	270	394	2	125	9.0e-21	94.9	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
644915888	515	34.9	24	515	5	499	0.0e+00	470	COG3534	Alpha-L-arabinofuranosidase	501
644915889	531	31.98	138	531	19	408	7.0e-39	155	COG0840	Methyl-accepting chemotaxis protein	408
644915891	256	37.6	1	254	2	254	1.0e-65	243	COG0084	Tat protein secretion system quality control protein TatD (DNase activity)	256
644915892	264	50.38	1	260	3	257	1.0e-83	302	COG1179	tRNA A37 threonylcarbamoyladenosine dehydratase	263
644915893	414	25.14	34	370	29	375	2.0e-62	233	COG0069	Glutamate synthase domain 2	485
644915895	1675	34.76	70	1675	62	1620	0.0e+00	916	COG2373	Uncharacterized conserved protein YfaS, alpha-2-macroglobulin family	1621
644915896	787	44.9	16	787	1	732	0.0e+00	685	COG4953	Membrane carboxypeptidase/penicillin-binding protein PbpC	733
644915898	353	29.44	4	341	16	371	6.0e-24	105	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
644915899	1032	40.08	3	1014	2	1008	0.0e+00	922	COG0841	Multidrug efflux pump subunit AcrB	1009
644915916	545	33.9	133	545	1	408	1.0e-50	194	COG0840	Methyl-accepting chemotaxis protein	408
644915917	189	50.8	4	186	3	188	6.0e-65	240	COG0450	Alkyl hydroperoxide reductase subunit AhpC (peroxiredoxin)	194
644915918	528	64.11	1	521	1	520	0.0e+00	761	COG3634	Alkyl hydroperoxide reductase subunit AhpF	520
644915921	410	18.26	183	408	92	329	6.0e-12	65.6	COG0642	Signal transduction histidine kinase	336
644915922	176	46.24	3	175	10	182	6.0e-42	163	COG4567	Two-component response regulator, ActR/RegA family, consists of REC and Fis-type HTH domains	182
644915925	446	26.8	4	441	9	451	8.0e-45	175	COG0534	Na+-driven multidrug efflux pump	455
644915927	896	14.92	306	896	184	768	2.0e-22	101	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
644915928	299	37.46	11	295	6	294	4.0e-45	175	COG2971	BadF-type ATPase, related to human N-acetylglucosamine kinase	301
644915929	790	30.88	34	644	125	726	2.0e-105	377	COG3525	N-acetyl-beta-hexosaminidase	732
644915930	440	33.79	6	438	2	413	6.0e-61	228	COG0738	Fucose permease	422
644915931	354	33.42	4	354	7	371	3.0e-50	192	COG4299	Predicted acyltransferase	371
644915932	381	45.01	13	381	11	380	3.0e-110	392	COG1820	N-acetylglucosamine-6-phosphate deacetylase	380
644915933	355	40.94	15	354	1	340	1.0e-75	277	COG2222	Fructoselysine-6-P-deglycase FrlB and related proteins with duplicated sugar isomerase (SIS) domain	340
644915934	342	39.64	5	340	1	332	8.0e-79	287	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
644915935	585	24.32	210	517	18	333	3.0e-24	106	COG3693	Endo-1,4-beta-xylanase, GH35 family	345
644915936	413	28	8	402	11	393	7.0e-41	161	COG2311	Uncharacterized membrane protein YeiB	394
644915937	311	45.71	1	308	2	313	6.0e-82	297	COG0123	Acetoin utilization deacetylase AcuC or a related deacetylase	340
644915940	1138	22.41	3	1138	1	1138	2.0e-82	301	COG1074	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)	1139
644915941	496	22.73	216	492	72	327	1.0e-16	81.8	COG0642	Signal transduction histidine kinase	336
644915942	1120	51.18	284	1118	1	804	0.0e+00	909	COG4196	Uncharacterized conserved protein, DUF2126 family	808
644915943	311	32.7	1	307	1	307	2.0e-46	179	COG2307	Uncharacterized conserved protein, Alpha-E superfamily	313
644915944	480	54.14	10	479	8	477	0.0e+00	613	COG2308	Uncharacterized conserved protein, circularly permuted ATPgrasp superfamily	488
644915945	422	32.68	1	396	1	361	1.0e-60	227	COG1858	Cytochrome c peroxidase	364
644915946	484	31.88	9	476	3	440	9.0e-57	214	COG3487	Uncharacterized iron-regulated protein	446
644915947	492	44.49	26	492	17	481	6.0e-124	437	COG3488	Uncharacterized conserved protein with two CxxC motifs, DUF1111 family	481
644915948	368	32.97	1	364	6	362	2.0e-57	216	COG3490	Uncharacterized protein	366
644915949	359	18.3	8	359	5	359	4.0e-07	49.2	COG3489	Predicted periplasmic lipoprotein	359
644915951	445	32.74	113	444	34	343	8.0e-60	224	COG3693	Endo-1,4-beta-xylanase, GH35 family	345
644915952	193	32.35	10	140	7	142	5.0e-12	64.2	COG1896	5'-deoxynucleotidase YfbR and related HD superfamily hydrolases	193
644915953	499	31.03	150	496	10	327	6.0e-40	159	COG0642	Signal transduction histidine kinase	336
644915954	233	48.91	4	231	2	225	9.0e-67	246	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
644915955	212	34.11	1	208	1	214	4.0e-35	141	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
644915958	727	29.65	7	322	1	341	7.0e-46	179	COG0515	Serine/threonine protein kinase	384
644915959	156	73.72	1	156	1	156	1.0e-59	222	COG2193	Bacterioferritin (cytochrome b1)	157
644915960	69	57.41	1	54	1	54	3.0e-11	60.3	COG2906	Bacterioferritin-associated ferredoxin	63
644915961	200	54.82	1	196	1	194	3.0e-70	257	COG0450	Alkyl hydroperoxide reductase subunit AhpC (peroxiredoxin)	194
644915963	175	44.81	17	170	1	154	2.0e-48	185	COG3265	Gluconate kinase	161
644915964	397	36.14	65	395	1	331	4.0e-78	285	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
644915969	317	25.25	8	303	2	291	4.0e-22	99.1	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
644915971	186	48.24	4	173	5	168	2.0e-42	165	COG4635	Protoporphyrinogen IX oxidase, menaquinone-dependent (flavodoxin domain)	175
644915973	574	45.18	1	568	1	498	0.0e+00	571	COG0442	Prolyl-tRNA synthetase	500
644915974	154	21.21	2	127	5	135	2.0e-14	72	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
644915977	96	36.49	1	74	8	80	6.0e-15	72.4	COG2331	Predicted nucleic acid-binding protein, contains Zn-ribbon domain	82
644915978	600	62.1	1	586	1	585	0.0e+00	923	COG0173	Aspartyl-tRNA synthetase	585
644915979	247	60.49	1	242	1	241	8.0e-91	326	COG0217	Transcriptional and/or translational regulatory protein YebC/TACO1	241
644915980	382	41.49	4	378	6	360	1.0e-89	324	COG0787	Alanine racemase	360
644915981	331	38.43	88	327	1	238	4.0e-55	208	COG0340	Biotin-(acetyl-CoA carboxylase) ligase	238
644915982	249	27.92	1	248	1	251	1.0e-26	113	COG1521	Pantothenate kinase type III	251
644915989	123	45.59	53	120	6	73	7.0e-09	52.7	COG0690	Preprotein translocase subunit SecE	73
644915990	177	57.39	1	176	1	176	1.0e-57	215	COG0250	Transcription antitermination factor NusG	178
644915991	143	69.72	2	143	1	141	9.0e-54	202	COG0080	Ribosomal protein L11	141
644915992	231	60.96	1	227	1	228	5.0e-79	287	COG0081	Ribosomal protein L1	228
644915993	176	43.1	1	173	1	174	4.0e-37	147	COG0244	Ribosomal protein L10	175
644915994	126	64.29	1	126	1	124	2.0e-22	98	COG0222	Ribosomal protein L7/L12	124
644915996	1407	50.75	20	853	7	808	0.0e+00	886	COG0086	DNA-directed RNA polymerase, beta' subunit/160 kD subunit	808
644915997	123	74.8	1	123	7	129	2.0e-47	180	COG0048	Ribosomal protein S12	129
644915998	156	62.16	2	149	1	148	2.0e-56	211	COG0049	Ribosomal protein S7	148
644915999	703	67.14	1	700	1	692	0.0e+00	995	COG0480	Translation elongation factor EF-G, a GTPase	697
644916000	407	76.66	1	407	1	394	0.0e+00	672	COG0050	Translation elongation factor EF-Tu, a GTPase	394
644916001	324	38.11	1	324	2	329	1.0e-87	316	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
644916002	166	35.54	1	166	5	167	2.0e-20	92.3	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
644916003	434	50.79	51	430	1	379	2.0e-91	330	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
644916004	317	29.87	3	301	1	294	1.0e-41	163	COG0524	Sugar or nucleoside kinase, ribokinase family	311
644916005	229	28.57	1	221	2	224	4.0e-32	131	COG2186	DNA-binding transcriptional regulator, FadR family	241
644916006	209	46.83	5	207	7	210	6.0e-55	207	COG0800	2-keto-3-deoxy-6-phosphogluconate aldolase	211
644916007	366	25.56	15	360	1	310	5.0e-26	112	COG0524	Sugar or nucleoside kinase, ribokinase family	311
644916008	470	43.22	6	470	3	461	0.0e+00	557	COG1904	Glucuronate isomerase	463
644916009	490	47.18	12	487	1	472	0.0e+00	486	COG0246	Mannitol-1-phosphate/altronate dehydrogenases	473
644916010	386	53.35	2	374	1	356	3.0e-105	375	COG3288	NAD/NADP transhydrogenase alpha subunit	356
644916012	467	59.96	4	464	1	461	0.0e+00	589	COG1282	NAD/NADP transhydrogenase beta subunit	463
644916014	796	37.92	36	707	173	798	3.0e-113	403	COG2374	Predicted extracellular nuclease	798
644916017	103	69.61	1	102	1	102	2.0e-37	147	COG0051	Ribosomal protein S10	104
644916018	214	61.61	2	209	1	211	4.0e-78	283	COG0087	Ribosomal protein L3	218
644916019	204	48.1	1	204	2	211	8.0e-53	200	COG0088	Ribosomal protein L4	214
644916020	98	56.38	6	98	1	94	8.0e-23	98.7	COG0089	Ribosomal protein L23	94
644916021	275	64.36	1	274	1	275	6.0e-111	393	COG0090	Ribosomal protein L2	275
644916022	91	72.83	1	91	1	92	2.0e-35	140	COG0185	Ribosomal protein S19	93
644916023	110	61.47	1	109	9	117	7.0e-33	132	COG0091	Ribosomal protein L22	120
644916024	224	64.02	12	224	1	214	3.0e-76	277	COG0092	Ribosomal protein S3	233
644916025	137	65.44	1	134	2	137	2.0e-46	178	COG0197	Ribosomal protein L16/L10AE	146
644916026	64	50.79	2	64	4	66	7.0e-07	45.6	COG0255	Ribosomal protein L29	69
644916027	88	63.64	9	85	9	85	1.0e-23	101	COG0186	Ribosomal protein S17	87
644916028	122	75.41	1	122	1	122	4.0e-50	189	COG0093	Ribosomal protein L14	122
644916029	105	53.33	1	104	2	104	7.0e-19	85.3	COG0198	Ribosomal protein L24	104
644916030	179	65.92	1	179	1	179	9.0e-75	272	COG0094	Ribosomal protein L5	180
644916031	101	55	42	101	2	61	9.0e-17	78.3	COG0199	Ribosomal protein S14	61
644916032	130	56.82	1	130	1	132	2.0e-46	178	COG0096	Ribosomal protein S8	132
644916033	177	51.98	1	176	1	176	9.0e-57	213	COG0097	Ribosomal protein L6P/L9E	178
644916034	116	55.08	4	116	8	125	7.0e-29	119	COG0256	Ribosomal protein L18	125
644916035	170	57.89	1	170	10	180	7.0e-56	210	COG0098	Ribosomal protein S5	181
644916036	61	56.36	6	60	1	55	1.0e-13	68.2	COG1841	Ribosomal protein L30/L7E	55
644916037	144	52	1	144	1	150	7.0e-30	123	COG0200	Ribosomal protein L15	152
644916038	441	48.13	6	430	13	432	1.0e-119	423	COG0201	Preprotein translocase subunit SecY	436
644916040	118	57.98	1	118	1	119	7.0e-40	155	COG0099	Ribosomal protein S13	121
644916041	130	69.23	1	130	1	129	6.0e-48	182	COG0100	Ribosomal protein S11	129
644916042	206	63.46	1	206	1	205	4.0e-59	220	COG0522	Ribosomal protein S4 or related protein	205
644916043	329	54.75	8	322	1	313	1.0e-97	350	COG0202	DNA-directed RNA polymerase, alpha subunit/40 kD subunit	317
644916044	131	68.1	1	116	1	116	5.0e-48	183	COG0203	Ribosomal protein L17	116
644916045	742	34.99	183	742	2	518	3.0e-107	383	COG1640	4-alpha-glucanotransferase	520
644916046	739	55.42	105	735	1	628	0.0e+00	800	COG0296	1,4-alpha-glucan branching enzyme	628
644916047	734	45.85	1	725	1	691	0.0e+00	717	COG1523	Pullulanase/glycogen debranching enzyme	697
644916048	815	45.92	15	815	7	748	0.0e+00	809	COG0058	Glucan phosphorylase	750
644916049	421	52.22	11	415	1	386	0.0e+00	510	COG0448	ADP-glucose pyrophosphorylase	393
644916050	518	32.08	6	517	2	476	1.0e-75	277	COG0297	Glycogen synthase	487
644916052	942	65.89	1	941	3	935	0.0e+00	1566	COG0178	Excinuclease UvrABC ATPase subunit	935
644916053	220	23.75	56	215	49	206	2.0e-17	83.1	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
644916054	448	25.79	38	384	44	384	4.0e-18	86.4	COG2814	Predicted arabinose efflux permease, MFS family	394
644916055	163	43.98	5	163	2	167	2.0e-40	158	COG0629	Single-stranded DNA-binding protein	167
644916056	292	21	12	276	14	280	1.0e-07	51	COG1091	dTDP-4-dehydrorhamnose reductase	281
644916057	404	46.49	1	403	2	412	2.0e-117	415	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
644916058	174	33.33	15	168	1	145	5.0e-36	143	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
644916059	277	50.55	1	272	3	272	8.0e-107	380	COG1210	UTP-glucose-1-phosphate uridylyltransferase	291
644916060	455	37.63	1	455	3	464	1.0e-105	376	COG1109	Phosphomannomutase	464
644916062	153	26.97	11	153	3	139	4.0e-06	44.2	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
644916064	281	41.82	6	278	3	272	5.0e-78	284	COG3220	Uncharacterized conserved protein, UPF0276 family	282
644916066	546	44.67	47	533	3	446	0.0e+00	462	COG0166	Glucose-6-phosphate isomerase	446
644916067	320	36.96	4	318	3	320	1.0e-79	290	COG0142	Geranylgeranyl pyrophosphate synthase	322
644916068	358	35.96	17	356	5	284	5.0e-88	318	COG0191	Fructose/tagatose bisphosphate aldolase	286
644916069	103	63.11	1	103	1	103	6.0e-34	135	COG0261	Ribosomal protein L21	103
644916070	85	80	1	85	1	84	2.0e-29	120	COG0211	Ribosomal protein L27	87
644916071	395	61.71	1	349	1	349	0.0e+00	497	COG0536	GTPase involved in cell partioning and DNA repair	369
644916072	373	52.43	5	372	1	368	8.0e-124	437	COG0263	Glutamate 5-kinase	369
644916073	352	33.24	3	347	1	349	2.0e-61	229	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
644916074	88	61.36	1	88	1	88	9.0e-14	68.4	COG0268	Ribosomal protein S20	88
644916075	680	26.69	357	680	14	330	3.0e-28	120	COG0642	Signal transduction histidine kinase	336
644916076	232	39.22	4	231	2	229	3.0e-45	175	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
644916077	152	33.81	1	137	2	140	9.0e-19	86.2	COG2703	Hemerythrin	144
644916078	150	40.44	1	133	1	136	2.0e-24	105	COG2703	Hemerythrin	144
644916080	177	46.37	3	177	44	215	4.0e-27	114	COG3122	Uncharacterized conserved protein YaiL, DUF2058 family	215
644916083	255	32.02	1	252	1	253	2.0e-14	73.1	COG0730	Uncharacterized membrane protein YfcA	258
644916085	190	33.9	4	180	13	188	2.0e-29	122	COG4445	tRNA isopentenyl-2-thiomethyl-A-37 hydroxylase MiaE (synthesis of 2-methylthio-cis-ribozeatin)	203
644916086	396	60.45	1	396	1	397	0.0e+00	548	COG3007	Trans-2-enoyl-CoA reductase	398
644916087	348	42.45	1	348	1	316	3.0e-87	315	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
644916088	291	47.78	1	291	4	296	1.0e-88	319	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
644916089	398	20.81	7	334	3	315	5.0e-19	89.3	COG3317	Uncharacterized lipoprotein	342
644916090	254	30.99	4	221	5	241	3.0e-28	119	COG1235	Phosphoribosyl 1,2-cyclic phosphodiesterase	269
644916093	216	42.05	21	215	1	190	3.0e-42	165	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
644916094	203	38.05	1	202	1	205	1.0e-28	119	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
644916096	133	27.05	7	126	2	121	3.0e-13	67.6	COG3682	Predicted transcriptional regulator	123
644916097	523	21.62	7	318	1	327	3.0e-16	80.4	COG4219	Signal transducer regulating beta-lactamase production, contains  metallopeptidase domain	337
644916099	146	31.45	13	133	14	134	5.0e-13	67.2	COG0848	Biopolymer transport protein ExbD	137
644916103	147	46.21	1	140	5	149	2.0e-42	164	COG0314	Molybdopterin synthase catalytic subunit	149
644916104	88	38.55	7	88	2	84	3.0e-15	73.4	COG1977	Molybdopterin converting factor, small subunit	84
644916105	159	59.49	1	158	1	157	1.0e-56	212	COG0315	Molybdenum cofactor biosynthesis enzyme	157
644916106	375	37.91	5	375	16	408	3.0e-82	299	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
644916107	343	41.06	85	342	14	271	6.0e-72	264	COG2171	Tetrahydrodipicolinate N-succinyltransferase	271
644916108	114	33.62	1	114	2	116	5.0e-26	109	COG1393	Arsenate reductase and related proteins, glutaredoxin family	117
644916109	217	44.83	2	204	1	203	3.0e-63	235	COG0177	Endonuclease III	211
644916110	400	34.24	5	399	4	392	7.0e-79	287	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
644916111	905	42.82	41	888	16	854	0.0e+00	804	COG2844	UTP:GlnB (protein PII) uridylyltransferase	867
644916112	256	55.08	1	254	1	255	4.0e-97	347	COG0024	Methionine aminopeptidase	255
644916113	250	57.54	1	248	1	251	3.0e-96	344	COG0052	Ribosomal protein S2	252
644916114	293	56.27	1	288	2	296	4.0e-88	317	COG0264	Translation elongation factor EF-Ts	296
644916115	244	58.72	8	241	4	238	3.0e-85	308	COG0528	Uridylate kinase	238
644916116	185	56.22	1	185	3	187	3.0e-62	231	COG0233	Ribosome recycling factor	187
644916117	250	48.95	4	239	9	245	6.0e-77	280	COG0020	Undecaprenyl pyrophosphate synthase	245
644916118	290	33.58	15	283	2	264	3.0e-31	129	COG0575	CDP-diglyceride synthetase	265
644916120	893	31.63	1	893	3	766	0.0e+00	546	COG4775	Outer membrane protein assembly factor BamA	766
644916122	340	46.45	4	339	2	337	2.0e-92	332	COG1044	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase	338
644916123	146	48.25	1	141	3	142	6.0e-44	169	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
644916124	260	57.69	1	260	1	260	7.0e-100	356	COG1043	Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase	260
644916125	404	44.33	15	389	3	379	6.0e-107	381	COG0763	Lipid A disaccharide synthetase	381
644916126	191	55.85	2	185	1	188	5.0e-61	227	COG0164	Ribonuclease HII	199
644916129	107	49.04	6	107	1	103	5.0e-20	89.5	COG0023	Translation initiation factor 1 (eIF-1/SUI1)	104
644916130	272	16.11	68	269	13	212	5.0e-06	45.2	COG1226	Voltage-gated potassium channel Kch	212
644916132	486	34.63	1	486	1	482	2.0e-89	323	COG4783	Putative Zn-dependent protease, contains TPR repeats	484
644916133	91	33.33	11	81	5	76	6.0e-13	65.7	COG0425	TusA-related sulfurtransferase	78
644916134	367	33.13	19	346	17	341	2.0e-36	146	COG0628	Predicted PurR-regulated permease PerM	355
644916135	973	33.92	34	941	4	903	0.0e+00	615	COG1025	Secreted/periplasmic Zn-dependent peptidases, insulinase-like	937
644916136	884	66.03	1	884	5	887	0.0e+00	1344	COG2609	Pyruvate dehydrogenase complex, dehydrogenase (E1) component	887
644916137	649	46.81	228	649	1	403	2.0e-95	343	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
644916142	238	22.92	35	226	2	187	1.0e-17	83.7	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
644916144	530	47.14	8	526	1	515	2.0e-107	383	COG0728	Peptidoglycan biosynthesis protein MviN/MurJ, putative lipid II flippase	518
644916145	315	45.1	7	312	4	304	4.0e-86	311	COG0196	FAD synthase	304
644916146	934	49.31	2	928	1	933	0.0e+00	1196	COG0060	Isoleucyl-tRNA synthetase	933
644916147	168	40.96	1	163	2	163	2.0e-32	131	COG0597	Lipoprotein signal peptidase	167
644916148	149	43.66	5	145	2	142	4.0e-34	137	COG1047	FKBP-type peptidyl-prolyl cis-trans isomerase 2	174
644916149	189	28.25	12	188	5	174	5.0e-20	91.2	COG4970	Tfp pilus assembly protein FimT	181
644916150	178	22.61	10	118	4	118	2.0e-07	49.2	COG4967	Tfp pilus assembly protein PilV	162
644916152	213	23.9	13	207	11	196	4.0e-17	81.6	COG4726	Tfp pilus assembly protein PilX	196
644916153	1215	27.57	246	1182	80	988	5.0e-86	313	COG3419	Tfp pilus assembly protein, tip-associated adhesin PilY1	1036
644916154	147	38.89	7	146	6	139	9.0e-24	102	COG4968	Tfp pilus assembly protein PilE	139
644916155	192	29.05	17	190	4	177	3.0e-20	92	COG4970	Tfp pilus assembly protein FimT	181
644916156	461	43.99	1	461	2	460	0.0e+00	494	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
644916158	542	43.43	267	531	9	268	4.0e-71	262	COG0171	NH3-dependent NAD+ synthetase	268
644916159	301	39.68	2	251	3	244	5.0e-57	215	COG4105	Outer membrane protein assembly factor BamD, BamD/ComL family	254
644916160	333	50.51	28	319	6	289	4.0e-83	301	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
644916161	250	44.49	5	250	3	249	3.0e-68	251	COG1496	Copper oxidase (laccase) domain	249
644916162	879	55.84	5	876	1	781	0.0e+00	961	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
644916164	327	24.15	1	301	1	308	8.0e-28	118	COG0451	Nucleoside-diphosphate-sugar epimerase	314
644916165	578	48.77	3	570	1	549	0.0e+00	643	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
644916166	163	51.55	1	161	3	163	9.0e-50	189	COG0440	Acetolactate synthase, small subunit	163
644916167	659	24.38	182	659	150	619	4.0e-59	223	COG1506	Dipeptidyl aminopeptidase/acylaminoacyl peptidase	620
644916168	650	22.76	28	650	5	619	3.0e-63	236	COG1506	Dipeptidyl aminopeptidase/acylaminoacyl peptidase	620
644916169	291	34.47	1	291	1	287	8.0e-37	147	COG0583	DNA-binding transcriptional regulator, LysR family	297
644916170	338	62.8	1	336	3	338	0.0e+00	537	COG0059	Ketol-acid reductoisomerase	338
644916171	289	38.5	39	262	4	226	1.0e-48	187	COG1183	Phosphatidylserine synthase	234
644916177	554	48.82	1	551	1	543	0.0e+00	502	COG2985	Uncharacterized membrane protein YbjL, putative transporter	544
644916178	1171	48.76	1	1164	2	1139	0.0e+00	1311	COG0587	DNA polymerase III, alpha subunit	1139
644916180	318	60.7	2	314	1	313	0.0e+00	471	COG0825	Acetyl-CoA carboxylase alpha subunit	317
644916181	1353	33.75	55	1011	21	836	0.0e+00	647	COG1643	HrpA-like RNA helicase	845
644916182	268	41.31	1	258	2	239	8.0e-64	237	COG2853	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, lipoprotein component MlaA	250
644916185	169	22.22	12	110	12	109	3.0e-06	45	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
644916188	798	29.97	521	785	2	282	5.0e-43	169	COG0515	Serine/threonine protein kinase	384
644916190	606	49.4	315	565	4	243	1.0e-82	300	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
644916191	337	30.23	118	332	52	251	5.0e-37	148	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
644916192	466	23.47	12	381	3	335	6.0e-39	155	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
644916193	655	30.75	10	650	8	639	4.0e-95	342	COG4776	Exoribonuclease II	645
644916194	475	34.69	154	414	38	308	1.0e-46	181	COG3608	Predicted deacylase	331
644916197	155	55.48	1	154	2	155	4.0e-60	223	COG0219	tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain	155
644916203	292	39.52	1	246	9	254	2.0e-44	172	COG3267	Type II secretory pathway, component ExeA (predicted ATPase)	269
644916205	580	45.47	64	566	2	500	0.0e+00	503	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
644916206	409	36.39	1	404	1	395	6.0e-89	321	COG1459	Type II secretory pathway, component PulF	397
644916208	131	26.05	1	119	3	121	2.0e-07	48.5	COG2165	Type II secretory pathway, pseudopilin PulG	149
644916214	562	26.91	3	271	54	328	6.0e-32	132	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
644916217	554	37.59	1	263	9	269	2.0e-43	170	COG3267	Type II secretory pathway, component ExeA (predicted ATPase)	269
644916219	178	32.95	1	172	2	172	2.0e-27	115	COG2716	Glycine cleavage system regulatory protein	176
644916220	78	44.29	1	70	1	70	3.0e-13	66.9	COG3089	Uncharacterized conserved protein YheU, UPF0270 family	72
644916221	221	44.55	16	216	8	208	2.0e-42	165	COG3571	Predicted hydrolase of the alpha/beta-hydrolase fold	213
644916222	350	44.38	3	347	4	352	6.0e-98	351	COG2933	23S rRNA C2498 (ribose-2'-O)-methylase RlmM	358
644916223	93	21.74	1	92	3	94	8.0e-06	42.3	COG1359	Quinol monooxygenase YgiN	100
644916224	80	35.53	6	80	2	77	4.0e-19	86.1	COG0425	TusA-related sulfurtransferase	78
644916226	188	48.47	8	169	3	164	2.0e-45	175	COG3101	Elongation factor P hydroxylase (EF-P beta-lysylation pathway)	180
644916227	301	34.59	1	262	5	262	3.0e-43	169	COG0258	5'-3' exonuclease	310
644916228	370	28.8	1	275	2	307	3.0e-40	159	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
644916229	723	37.17	12	392	2	355	4.0e-64	239	COG3199	Predicted polyphosphate- or ATP-dependent NAD kinase	355
644916232	403	36.05	8	403	1	393	8.0e-96	344	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
644916233	135	52.76	7	132	4	130	7.0e-51	192	COG0229	Peptide methionine sulfoxide reductase MsrB	140
644916234	223	26.55	39	215	29	188	2.0e-28	119	COG2818	3-methyladenine DNA glycosylase Tag	188
644916238	317	39.4	8	308	2	292	5.0e-74	271	COG1131	ABC-type multidrug transport system, ATPase component	293
644916239	257	21.4	29	256	43	256	8.0e-10	57.5	COG1682	ABC-type polysaccharide/polyol phosphate export permease	263
644916240	276	51.97	5	129	10	136	4.0e-41	162	COG2904	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF, N-terminal domain	137
644916241	463	28.11	196	410	15	215	8.0e-36	145	COG2114	Adenylate cyclase, class 3	227
644916244	199	27.72	18	198	25	208	2.0e-12	65.7	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
644916253	424	46.17	5	420	1	414	2.0e-123	436	COG4536	Mg2+ and Co2+ transporter CorB, contains DUF21, CBS pair, and CorC-HlyC domains	423
644916254	262	36.54	3	261	6	265	5.0e-44	171	COG4137	ABC-type uncharacterized transport system, permease component	265
644916255	523	60.04	56	507	1	451	0.0e+00	626	COG0541	Signal recognition particle GTPase	451
644916256	81	62.96	1	81	1	80	4.0e-25	106	COG0228	Ribosomal protein S16	87
644916257	179	38.51	7	179	6	172	4.0e-35	141	COG0806	Ribosomal 30S subunit maturation factor RimM, required for 16S rRNA processing	174
644916258	262	54.62	7	254	2	239	2.0e-92	332	COG0336	tRNA G37 N-methylase TrmD	240
644916259	118	64.91	4	117	2	115	5.0e-41	159	COG0335	Ribosomal protein L19	115
644916260	264	21.46	1	259	1	240	2.0e-19	89.5	COG1651	Protein-disulfide isomerase	244
644916261	439	50.46	1	318	1	328	2.0e-102	366	COG0460	Homoserine dehydrogenase	333
644916262	471	29.39	1	467	1	410	5.0e-99	355	COG0498	Threonine synthase	411
644916264	580	41.79	37	557	1	491	3.0e-103	369	COG0608	Single-stranded DNA-specific exonuclease, DHH superfamily, may be involved in archaeal DNA replication intiation	491
644916267	300	63.6	63	300	1	239	2.0e-96	346	COG1186	Protein chain release factor B	239
644916268	498	58.12	1	498	1	501	0.0e+00	680	COG1190	Lysyl-tRNA synthetase (class II)	502
644916269	227	63.23	5	225	1	223	3.0e-99	354	COG0692	Uracil DNA glycosylase	223
644916270	535	61.45	3	535	6	529	0.0e+00	788	COG1866	Phosphoenolpyruvate carboxykinase, ATP-dependent	529
644916271	278	28.97	1	277	1	289	2.0e-44	172	COG1639	HD-like signal output (HDOD) domain, no enzymatic activity	289
644916272	323	29.3	17	321	2	304	1.0e-47	184	COG0354	Folate-binding Fe-S cluster repair protein YgfZ, possible role in tRNA modification	305
644916273	107	53.42	28	100	16	88	1.0e-16	78.4	COG2938	Succinate dehydrogenase flavin-adding protein, antitoxin component of the CptAB toxin-antitoxin module	94
644916275	552	54.91	22	540	9	509	0.0e+00	670	COG0029	Aspartate oxidase	518
644916276	200	35.83	9	195	1	181	3.0e-31	128	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
644916277	247	24.36	18	157	8	157	2.0e-07	50	COG3073	Negative regulator of sigma E activity	213
644916278	328	24.62	14	326	7	320	5.0e-34	138	COG3026	Negative regulator of sigma E activity	320
644916279	155	28.47	1	144	1	143	4.0e-18	84.2	COG3086	Positive regulator of sigma E activity	150
644916280	465	43.15	23	357	27	343	1.0e-70	261	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
644916281	599	67	1	599	3	602	0.0e+00	1035	COG0481	Translation elongation factor EF-4, membrane-bound GTPase	603
644916282	283	29.03	70	174	9	163	3.0e-12	65.8	COG0681	Signal peptidase I	166
644916284	229	51.53	8	229	7	232	1.0e-64	239	COG0571	dsRNA-specific ribonuclease	235
644916285	296	52.53	1	295	1	296	4.0e-105	374	COG1159	GTPase Era, involved in 16S rRNA processing	298
644916286	236	30.33	1	235	1	240	2.0e-20	92.7	COG1381	Recombinational DNA repair protein (RecF pathway)	251
644916287	932	42.8	237	492	82	326	2.0e-44	174	COG0642	Signal transduction histidine kinase	336
644916288	296	48.32	3	290	2	299	1.0e-101	362	COG0031	Cysteine synthase	300
644916289	747	50.95	60	744	43	700	0.0e+00	762	COG0317	(p)ppGpp synthase/hydrolase, HD superfamily	701
644916292	217	38.64	1	216	1	178	5.0e-45	174	COG0563	Adenylate kinase or related kinase	178
644916293	239	38.3	3	232	2	219	9.0e-35	140	COG1214	tRNA A37 threonylcarbamoyladenosine modification protein TsaB	220
644916294	264	40	1	263	4	266	4.0e-57	214	COG1968	Undecaprenyl pyrophosphate phosphatase UppP	270
644916295	431	43.87	7	423	13	432	3.0e-123	435	COG1362	Aspartyl aminopeptidase	437
644916297	382	16.67	82	370	92	381	3.0e-06	46.9	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
644916298	334	41.12	1	313	3	314	9.0e-87	313	COG0180	Tryptophanyl-tRNA synthetase	314
644916300	106	20.21	14	106	11	104	6.0e-08	49.2	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
644916302	435	45.17	10	435	4	448	0.0e+00	528	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
644916305	302	32.93	14	259	1	242	1.0e-49	190	COG0037	tRNA(Ile)-lysidine synthase TilS/MesJ	298
644916307	236	26.45	1	235	3	240	8.0e-31	127	COG1385	16S rRNA U1498 N3-methylase RsmE	246
644916309	676	48.01	28	676	7	654	0.0e+00	681	COG3590	Predicted metalloendopeptidase	654
644916310	162	23.08	12	152	9	136	2.0e-07	48.9	COG3418	Flagellar biosynthesis/type III secretory pathway chaperone	146
644916311	104	28.57	1	98	1	88	7.0e-06	42.2	COG2747	Negative regulator of flagellin synthesis (anti-sigma28 factor)	93
644916313	228	37.22	46	225	43	218	7.0e-29	120	COG1261	Flagella basal body P-ring formation protein FlgA	220
644916314	316	36.97	3	165	1	164	6.0e-33	135	COG0835	Chemotaxis signal transduction protein	165
644916315	287	37.69	18	285	2	264	5.0e-71	261	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
644916316	134	36.57	2	134	1	133	7.0e-27	113	COG1815	Flagellar basal body rod protein FlgB	133
644916317	145	47.59	1	145	1	137	5.0e-39	153	COG1558	Flagellar basal body rod protein FlgC	137
644916318	238	31.06	2	236	1	221	3.0e-30	125	COG1843	Flagellar hook assembly protein FlgD	222
644916321	250	46.61	1	247	1	249	2.0e-74	272	COG4787	Flagellar basal body rod protein FlgF	251
644916322	261	54.34	1	261	1	264	2.0e-79	288	COG4786	Flagellar basal body rod protein FlgG	265
644916323	234	39.91	5	227	2	227	4.0e-51	194	COG2063	Flagellar basal body L-ring protein FlgH	230
644916324	372	54.5	6	372	2	365	3.0e-124	438	COG1706	Flagellar basal body P-ring protein FlgI	365
644916325	336	32.32	151	314	20	176	1.0e-29	124	COG1705	Flagellum-specific peptidoglycan hydrolase FlgJ	201
644916326	1060	28.66	1	475	2	461	4.0e-61	230	COG1256	Flagellar hook-associated protein FlgK	552
644916327	533	22.78	1	268	1	278	6.0e-24	105	COG1344	Flagellin and related hook-associated protein FlgL	360
644916328	576	32.28	3	287	1	285	6.0e-32	132	COG1344	Flagellin and related hook-associated protein FlgL	360
644916330	140	29.2	3	139	2	133	4.0e-21	93.9	COG3791	Uncharacterized conserved protein	133
644916332	280	24.27	6	221	3	241	1.0e-17	83.8	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
644916333	320	35.58	216	319	22	125	2.0e-19	89.9	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
644916334	679	20.1	73	651	42	586	4.0e-20	93.9	COG4206	Outer membrane cobalamin receptor protein	608
644916335	346	31.11	166	344	10	180	2.0e-30	126	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
644916336	714	17.15	19	714	48	768	5.0e-28	120	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
644916338	206	24.32	15	194	26	210	6.0e-15	74.1	COG3201	Nicotinamide riboside transporter PnuC	222
644916341	180	25.97	1	177	2	182	2.0e-21	95.4	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
644916343	134	35.34	2	132	1	130	7.0e-21	93	COG2764	Uncharacterized conserved protein PhnB, glyoxalase superfamily	136
644916345	269	43.24	13	269	5	263	1.0e-61	229	COG3971	2-keto-4-pentenoate hydratase	264
644916347	289	24.57	18	286	1	282	1.0e-25	110	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
644916349	271	22.51	15	269	17	266	2.0e-10	59.9	COG3384	Aromatic ring-opening dioxygenase, catalytic subunit, LigB family	268
644916352	756	20.72	7	756	11	768	1.0e-32	135	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
644916353	419	22.76	14	405	26	435	8.0e-16	78.7	COG2271	Sugar phosphate permease	448
644916354	266	40.22	10	265	9	279	3.0e-55	208	COG2175	Taurine dioxygenase, alpha-ketoglutarate-dependent	286
644916355	220	28.43	1	203	4	207	5.0e-24	104	COG1802	DNA-binding transcriptional regulator, GntR family	230
644916356	230	43.06	2	217	42	246	2.0e-43	169	COG1712	Predicted dinucleotide-utilizing enzyme	255
644916357	233	34.56	9	224	11	226	4.0e-30	125	COG1802	DNA-binding transcriptional regulator, GntR family	230
644916360	117	29.81	15	117	3	106	2.0e-18	84.6	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
644916361	617	31.43	5	608	9	531	1.0e-111	397	COG0405	Gamma-glutamyltranspeptidase	539
644916363	407	24.62	3	394	1	382	1.0e-42	167	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
644916364	302	56.03	1	292	1	304	2.0e-90	325	COG4569	Acetaldehyde dehydrogenase (acetylating)	310
644916365	341	23.7	6	341	1	345	6.0e-48	185	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
644916366	322	31.94	9	260	5	265	1.0e-41	163	COG1018	Ferredoxin-NADP reductase	266
644916368	340	33.14	1	331	17	351	3.0e-75	275	COG0252	L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D	351
644916371	215	24.83	8	143	24	172	2.0e-06	46.2	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
644916375	84	46.15	1	78	1	78	1.0e-14	71.5	COG5460	Uncharacterized conserved protein, DUF2164 family	82
644916378	511	19.82	63	477	28	403	4.0e-17	83.1	COG1228	Imidazolonepropionase or related amidohydrolase	406
644916381	322	31.11	6	306	8	284	4.0e-38	152	COG4974	Site-specific recombinase XerD	300
644916383	206	43.35	1	203	2	197	2.0e-58	218	COG0118	Imidazoleglycerol phosphate synthase glutamine amidotransferase subunit HisH	204
644916384	259	52.38	8	256	3	254	5.0e-79	287	COG0107	Imidazole glycerol phosphate synthase subunit HisF	256
644916385	230	40	7	224	5	223	7.0e-50	190	COG1083	CMP-N-acetylneuraminic acid synthetase	228
644916388	399	22.92	2	376	3	370	9.0e-53	201	COG0381	UDP-N-acetylglucosamine 2-epimerase	383
644916389	333	44.24	2	331	14	341	8.0e-98	350	COG2089	Sialic acid synthase SpsE, contains C-terminal SAF domain	347
644916391	376	31.79	15	376	2	351	4.0e-77	282	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
644916392	332	35.74	9	318	2	310	4.0e-54	205	COG0451	Nucleoside-diphosphate-sugar epimerase	314
644916395	693	27.94	7	408	6	393	1.0e-33	138	COG1345	Flagellar capping protein FliD	483
644916396	125	42.4	1	125	1	121	2.0e-23	101	COG1516	Flagellin-specific chaperone FliS	132
644916397	127	38.32	16	122	15	121	6.0e-20	89.6	COG1516	Flagellin-specific chaperone FliS	132
644916399	476	43.19	1	476	1	459	8.0e-119	420	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
644916400	368	25.23	18	342	3	247	1.0e-44	173	COG0152	Phosphoribosylaminoimidazole-succinocarboxamide synthase	247
644916402	415	25.98	140	413	65	333	8.0e-25	108	COG0642	Signal transduction histidine kinase	336
644916403	488	44.56	2	484	1	463	6.0e-126	444	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
644916405	120	44	46	120	32	105	5.0e-14	70	COG1677	Flagellar hook-basal body complex protein FliE	105
644916406	558	37.25	15	558	11	545	7.0e-114	404	COG1766	Flagellar biosynthesis/type III secretory pathway M-ring protein FliF/YscJ	545
644916407	343	45.35	1	343	1	339	3.0e-88	318	COG1536	Flagellar motor switch protein FliG	339
644916408	281	27.23	37	245	23	218	2.0e-15	76.9	COG1317	Flagellar biosynthesis/type III secretory pathway protein FliH	234
644916409	480	58.73	6	445	3	441	0.0e+00	596	COG1157	Flagellar biosynthesis/type III secretory pathway ATPase	441
644916410	144	27.01	7	142	5	141	3.0e-06	44.5	COG2882	Flagellar biosynthesis chaperone FliJ	148
644916411	570	27.14	5	268	55	323	2.0e-31	131	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
644916414	822	38.3	1	798	2	711	0.0e+00	624	COG0643	Chemotaxis protein histidine kinase CheA	716
644916415	189	37.34	13	170	1	153	2.0e-34	138	COG0835	Chemotaxis signal transduction protein	165
644916416	913	39.06	531	866	48	408	8.0e-54	205	COG0840	Methyl-accepting chemotaxis protein	408
644916417	281	40.59	18	281	1	267	3.0e-72	265	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
644916418	213	37.65	23	183	2	158	1.0e-38	153	COG1871	Chemotaxis receptor (MCP) glutamine deamidase CheD	164
644916419	354	47.86	7	354	2	345	3.0e-97	348	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
644916420	102	22.92	7	101	8	103	6.0e-08	49.2	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
644916422	114	25	6	114	5	114	1.0e-06	45.1	COG2198	HPt (histidine-containing phosphotransfer) domain	122
644916424	176	23.53	7	176	1	159	3.0e-19	88.4	COG1580	Flagellar basal body-associated protein FliL	159
644916425	332	43.69	1	322	1	324	1.0e-91	329	COG1868	Flagellar motor switch protein FliM	332
644916426	147	40.44	1	136	7	136	8.0e-23	99.7	COG1886	Flagellar motor switch/type III secretory pathway protein FliN	136
644916427	167	33.86	36	160	3	128	4.0e-16	77.7	COG3190	Flagellar biogenesis protein FliO	137
644916428	283	58.88	68	281	34	247	7.0e-75	274	COG1338	Flagellar biosynthetic protein FliP	248
644916429	89	42.7	1	89	1	89	9.0e-14	68.6	COG1987	Flagellar biosynthesis protein FliQ	89
644916430	257	40.08	1	257	1	256	3.0e-39	155	COG1684	Flagellar biosynthesis protein FliR	258
644916431	377	45.15	2	362	1	361	1.0e-114	406	COG1377	Flagellar biosynthesis protein FlhB	363
644916432	750	62.12	30	750	8	730	0.0e+00	1017	COG0376	Catalase (peroxidase I)	730
644916433	535	32.67	38	535	1	428	1.0e-93	337	COG0281	Malic enzyme	432
644916434	377	26.94	183	370	30	219	2.0e-10	60	COG3063	Tfp pilus assembly protein PilF	250
644916435	744	50.9	20	740	8	696	0.0e+00	843	COG1298	Flagellar biosynthesis pathway, component FlhA	696
644916436	506	30.26	125	499	27	403	2.0e-59	223	COG1419	Flagellar biosynthesis GTPase FlhF	407
644916437	272	35.09	8	268	3	259	1.0e-52	199	COG0455	MinD-like ATPase involved in chromosome partitioning or flagellar assembly	262
644916438	235	42.6	15	235	29	247	5.0e-51	194	COG1191	DNA-directed RNA polymerase specialized sigma subunit	247
644916441	264	30.6	33	264	3	217	1.0e-37	150	COG3143	Chemotaxis regulator CheZ, phosphatase of CheY~P	217
644916442	789	37.07	5	787	5	711	0.0e+00	600	COG0643	Chemotaxis protein histidine kinase CheA	716
644916443	379	44.56	4	378	3	342	1.0e-92	333	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
644916444	246	40.65	1	245	1	246	3.0e-63	235	COG1291	Flagellar motor component MotA	266
644916445	305	33.47	1	221	1	244	8.0e-39	154	COG1360	Flagellar motor protein MotB	244
644916447	265	37.7	1	249	2	248	1.0e-46	180	COG1192	Cellulose biosynthesis protein BcsQ	259
644916449	161	38.67	11	160	13	162	4.0e-37	147	COG0835	Chemotaxis signal transduction protein	165
644916452	255	36.28	17	229	3	212	3.0e-30	125	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
644916453	220	32.88	1	216	2	217	4.0e-38	151	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
644916454	257	60.5	23	256	6	241	1.0e-85	309	COG2227	2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase	243
644916455	442	38.63	13	426	7	420	4.0e-83	302	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
644916456	856	55.98	1	841	1	802	0.0e+00	1024	COG0188	DNA gyrase/topoisomerase IV, subunit A	804
644916457	377	46.57	105	377	1	277	3.0e-90	326	COG0077	Prephenate dehydratase	279
644916458	742	43.29	313	734	7	425	1.0e-123	437	COG0128	5-enolpyruvylshikimate-3-phosphate synthase	428
644916459	308	37.5	13	308	17	261	3.0e-59	222	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
644916460	468	62.56	19	448	1	430	0.0e+00	651	COG2895	Sulfate adenylyltransferase subunit 1, EFTu-like GTPase family	431
644916462	232	47.41	1	232	7	235	5.0e-64	237	COG0284	Orotidine-5'-phosphate decarboxylase	240
644916463	228	52.49	5	224	4	220	6.0e-65	240	COG0283	Cytidylate kinase	222
644916465	394	36.79	5	388	4	378	7.0e-70	257	COG2956	Lipopolysaccharide biosynthesis regulator YciM, contains six TPR domains and a predicted metal-binding C-terminal domain	389
644916466	560	59.47	1	532	1	524	0.0e+00	586	COG0539	Ribosomal protein S1	541
644916471	98	55.32	1	94	2	94	1.0e-30	124	COG0776	Bacterial nucleoid DNA-binding protein	94
644916472	476	46.85	11	338	2	333	5.0e-115	408	COG0836	Mannose-1-phosphate guanylyltransferase	333
644916473	356	26.33	5	313	6	312	5.0e-34	138	COG0472	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase	319
644916474	293	16.86	1	292	21	344	1.0e-05	43.8	COG3765	LPS O-antigen chain length determinant protein, WzzB/FepE family	347
644916475	353	24.6	1	351	1	374	1.0e-25	110	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
644916476	349	22.55	1	348	4	377	3.0e-18	86.2	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
644916477	372	24.18	1	351	1	348	1.0e-17	84.7	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
644916478	425	19.84	4	365	3	322	6.0e-18	85.4	COG2327	Polysaccharide pyruvyl transferase family protein WcaK	385
644916481	280	29.57	96	277	71	251	2.0e-20	93.4	COG1922	UDP-N-acetyl-D-mannosaminuronic acid transferase, WecB/TagA/CpsF family	253
644916484	333	32.36	1	333	1	314	2.0e-52	199	COG0451	Nucleoside-diphosphate-sugar epimerase	314
644916485	465	31.72	13	465	2	416	4.0e-67	249	COG1236	RNA processing exonuclease, beta-lactamase fold, Cft2 family	427
644916486	86	38.1	4	86	3	82	4.0e-08	49.5	COG2336	Antitoxin component of the MazEF toxin-antitoxin module	82
644916487	111	40.54	6	111	1	110	9.0e-16	75.4	COG2337	mRNA-degrading endonuclease, toxin component of the MazEF toxin-antitoxin module	112
644916489	388	39.42	1	388	1	414	2.0e-124	439	COG1004	UDP-glucose 6-dehydrogenase	414
644916491	489	34.15	1	487	2	456	1.0e-82	300	COG2211	Na+/melibiose symporter or related transporter	467
644916495	325	25.32	114	315	67	294	2.0e-17	83.3	COG4974	Site-specific recombinase XerD	300
644916518	831	32.02	147	319	43	219	2.0e-20	95.2	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
644916520	637	54.82	34	634	1	583	0.0e+00	782	COG0441	Threonyl-tRNA synthetase	589
644916521	143	61.54	1	143	34	176	1.0e-44	172	COG0290	Translation initiation factor IF-3	176
644916524	119	72.88	1	118	1	118	1.0e-36	144	COG0292	Ribosomal protein L20	118
644916525	329	57.91	1	328	3	335	5.0e-129	453	COG0016	Phenylalanyl-tRNA synthetase alpha subunit	335
644916526	794	45.87	148	794	1	650	0.0e+00	665	COG0072	Phenylalanyl-tRNA synthetase beta subunit	650
644916527	107	46.74	12	103	2	93	1.0e-27	114	COG0776	Bacterial nucleoid DNA-binding protein	94
644916528	117	24.49	19	116	1	97	2.0e-13	67.5	COG0789	DNA-binding transcriptional regulator, MerR family	124
644916534	187	34.01	1	187	2	184	9.0e-25	106	COG0693	Putative intracellular protease/amidase	188
644916535	580	16.37	12	572	1	459	4.0e-28	119	COG0277	FAD/FMN-containing dehydrogenase	459
644916536	204	32.67	6	200	1	201	2.0e-26	112	COG0625	Glutathione S-transferase	211
644916539	402	23.98	12	374	4	344	3.0e-42	166	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
644916540	163	20	11	162	7	162	2.0e-06	45.3	COG5517	3-phenylpropionate/cinnamic acid dioxygenase, small subunit	164
644916541	629	22.63	9	343	7	347	4.0e-33	136	COG2072	Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD	443
644916543	329	27.33	24	318	2	295	9.0e-43	167	COG0583	DNA-binding transcriptional regulator, LysR family	297
644916545	319	36.89	1	303	2	310	3.0e-82	298	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
644916546	162	34.42	1	154	9	159	1.0e-16	79.2	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
644916547	434	51.33	51	426	1	375	1.0e-90	327	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
644916548	1276	31.62	13	349	19	343	5.0e-47	184	COG3866	Pectate lyase	345
644916550	781	27.11	327	777	30	445	2.0e-62	234	COG3507	Beta-xylosidase	549
644916551	264	38.98	6	254	1	251	2.0e-48	186	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
644916552	280	54.68	5	280	1	278	6.0e-108	383	COG3717	5-keto 4-deoxyuronate isomerase	278
644916553	832	36.56	498	825	46	352	5.0e-68	253	COG4225	Rhamnogalacturonyl hydrolase YesR	357
644916555	467	36.71	4	413	27	441	2.0e-83	303	COG5434	Polygalacturonase	542
644916556	260	39.08	7	235	4	239	1.0e-41	163	COG2186	DNA-binding transcriptional regulator, FadR family	241
644916557	527	51.24	123	526	1	380	1.0e-129	457	COG2721	Altronate dehydratase	381
644916558	339	25.52	13	337	1	310	2.0e-44	173	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
644916559	255	29.51	16	250	1	244	8.0e-31	127	COG1414	DNA-binding transcriptional regulator, IclR family	246
644916560	296	26.45	2	275	10	276	1.0e-30	126	COG3618	Predicted metal-dependent hydrolase, TIM-barrel fold	279
644916562	557	15.1	27	557	64	603	1.0e-29	125	COG1874	Beta-galactosidase GanA	673
644916564	507	19.72	160	421	86	363	2.0e-06	47.8	COG0644	Dehydrogenase (flavoprotein)	396
644916568	251	22.52	1	215	6	205	2.0e-10	59.9	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
644916569	421	34.27	178	415	1	248	3.0e-45	176	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
644916571	222	33.82	7	213	23	224	6.0e-40	157	COG2977	4'-phosphopantetheinyl transferase EntD (siderophore biosynthesis)	228
644916574	89	35.06	1	77	1	77	6.0e-12	62.6	COG5007	Acid stress-induced BolA-like protein IbaG/YrbA, predicted regulator of iron metabolism	80
644916575	108	53.85	1	103	1	104	1.0e-34	138	COG0278	Glutaredoxin-related protein	105
644916576	248	28.71	1	98	1	100	7.0e-12	64.6	COG0607	Rhodanese-related sulfurtransferase	110
644916578	138	21.85	2	115	1	116	8.0e-08	49.8	COG1393	Arsenate reductase and related proteins, glutaredoxin family	117
644916581	528	40.07	5	527	12	549	4.0e-127	448	COG3604	Transcriptional regulator containing GAF, AAA-type ATPase, and DNA-binding Fis domains	550
644916582	536	24.26	174	523	10	343	3.0e-25	110	COG3852	Signal transduction histidine kinase, nitrogen specific	363
644916583	193	63.87	1	191	2	192	4.0e-60	224	COG4657	Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfA subunit	193
644916584	175	44.07	1	172	4	179	3.0e-43	167	COG2878	Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit	198
644916585	505	45.38	7	503	2	494	2.0e-127	449	COG4656	Na+-translocating ferredoxin:NAD+ oxidoreductase  RNF, RnfC subunit	529
644916586	366	43.11	5	344	3	335	6.0e-78	284	COG4658	Na+-translocating ferredoxin:NAD+ oxidoreductase  RNF, RnfD subunit	338
644916587	218	39.49	12	205	1	195	2.0e-44	172	COG4659	Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfG subunit	195
644916588	253	52.83	27	238	1	212	3.0e-64	238	COG4660	Na+-translocating ferredoxin:NAD+ oxidoreductase  RNF, RnfE subunit	212
644916589	88	44	1	74	4	78	9.0e-14	68.4	COG2914	Putative antitoxin component PasI (RatB) of the RatAB toxin-antitoxin module, ubiquitin-RnfH superfamily	99
644916591	357	43.58	3	357	1	352	4.0e-96	344	COG4148	ABC-type molybdate transport system, ATPase component	352
644916592	230	43.78	5	221	2	218	1.0e-55	210	COG4149	ABC-type molybdate transport system, permease component	225
644916593	253	29.07	1	250	2	257	4.0e-41	161	COG0725	ABC-type molybdate transport system, periplasmic component	258
644916596	292	71.58	3	280	1	278	1.0e-121	429	COG1348	Nitrogenase subunit NifH, an ATPase	278
644916597	493	36.63	22	488	1	456	2.0e-100	359	COG2710	Nitrogenase molybdenum-iron protein, alpha and beta chains	456
644916598	523	30.31	33	510	1	444	2.0e-86	313	COG2710	Nitrogenase molybdenum-iron protein, alpha and beta chains	456
644916599	69	41.79	4	69	3	66	6.0e-07	45.8	COG5554	Nitrogen fixation protein	69
644916606	216	30.19	10	209	12	209	2.0e-16	79.6	COG2802	Uncharacterized protein, similar to the N-terminal domain of Lon protease	221
644916607	207	25.49	1	199	1	201	1.0e-21	96.8	COG0625	Glutathione S-transferase	211
644916608	211	30.95	37	200	30	194	1.0e-23	103	COG3145	Alkylated DNA repair dioxygenase AlkB	194
644916617	370	62.7	1	369	1	370	0.0e+00	487	COG0686	Alanine dehydrogenase	371
644916618	396	35.09	1	395	1	396	6.0e-58	218	COG3213	Uncharacterized protein involved in response to NO	396
644916621	323	25.29	8	256	6	249	7.0e-25	108	COG2014	Uncharacterized conserved protein, contains DUF4213 and DUF364 domains	250
644916623	426	23.74	14	422	3	381	2.0e-35	143	COG0247	Fe-S oxidoreductase	388
644916624	158	67.95	1	156	1	156	3.0e-57	213	COG2193	Bacterioferritin (cytochrome b1)	157
644916625	69	50	1	56	1	56	3.0e-07	46.8	COG2906	Bacterioferritin-associated ferredoxin	63
644916626	130	21.88	9	130	6	132	4.0e-10	57.3	COG2703	Hemerythrin	144
644916633	471	33.11	14	459	14	452	8.0e-89	321	COG2710	Nitrogenase molybdenum-iron protein, alpha and beta chains	456
644916634	461	26.01	6	440	22	440	2.0e-57	217	COG2710	Nitrogenase molybdenum-iron protein, alpha and beta chains	456
644916639	106	41.07	47	102	2	57	1.0e-12	64.6	COG3411	(2Fe-2S) ferredoxin	64
644916643	107	41.12	1	107	4	110	5.0e-29	119	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
644916644	317	40.94	1	129	3	149	6.0e-28	118	COG0822	NifU homolog involved in Fe-S cluster formation	150
644916645	402	52.73	4	385	3	386	0.0e+00	508	COG1104	Cysteine sulfinate desulfinase/cysteine desulfurase or related enzyme	386
644916646	382	41.47	2	373	1	381	8.0e-93	334	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
644916647	273	52.53	23	220	2	194	3.0e-65	241	COG1045	Serine acetyltransferase	194
644916652	431	50.64	10	397	1	383	0.0e+00	465	COG1219	ATP-dependent protease Clp, ATPase subunit	408
644916653	180	33.33	1	176	1	151	1.0e-24	106	COG0716	Flavodoxin	151
644916654	955	31.21	215	505	26	337	5.0e-52	200	COG3693	Endo-1,4-beta-xylanase, GH35 family	345
644916656	737	35.74	302	590	55	336	2.0e-39	158	COG0642	Signal transduction histidine kinase	336
644916658	494	38.98	9	487	5	492	8.0e-104	371	COG0248	Exopolyphosphatase/pppGpp-phosphohydrolase	492
644916660	217	50.3	47	214	1	167	3.0e-62	231	COG0225	Peptide methionine sulfoxide reductase MsrA	174
644916662	221	44.94	22	199	2	178	1.0e-43	169	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
644916663	395	28.65	20	373	23	394	3.0e-71	262	COG0019	Diaminopimelate decarboxylase	394
644916664	399	46.72	1	392	1	380	5.0e-119	421	COG1748	Saccharopine dehydrogenase, NADP-dependent	389
644916665	639	44.31	1	637	17	650	0.0e+00	713	COG1166	Arginine decarboxylase (spermidine biosynthesis)	652
644916667	308	45.25	6	307	1	294	1.0e-84	307	COG1090	NAD dependent epimerase/dehydratase family enzyme	297
644916668	174	32.87	1	140	7	146	2.0e-27	115	COG0071	Molecular chaperone IbpA, HSP20 family	146
644916670	329	32.1	2	324	11	325	1.0e-61	230	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
644916671	639	29.08	161	550	42	406	9.0e-52	198	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
644916673	720	44.18	314	603	2	292	1.0e-84	308	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
644916674	391	42.93	6	391	2	392	1.0e-89	323	COG0183	Acetyl-CoA acetyltransferase	392
644916676	441	44.57	1	435	1	441	1.0e-96	346	COG0544	FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)	441
644916677	214	73.98	17	212	2	197	6.0e-87	313	COG0740	ATP-dependent protease ClpP, protease subunit	200
644916678	429	71.29	18	428	1	408	0.0e+00	687	COG1219	ATP-dependent protease Clp, ATPase subunit	408
644916679	806	65.81	4	781	1	781	0.0e+00	1171	COG0466	ATP-dependent Lon protease, bacterial type	782
644916680	90	62.22	1	90	2	91	3.0e-27	113	COG0776	Bacterial nucleoid DNA-binding protein	94
644916682	283	34.78	7	281	1	268	2.0e-56	212	COG0796	Glutamate racemase	269
644916683	477	35.77	44	453	19	423	1.0e-72	267	COG1322	DNA anti-recombination protein (rearrangement mutator) RmuC	448
644916685	364	26.7	7	357	81	432	2.0e-65	242	COG2265	tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family	432
644916686	227	33.05	1	227	4	233	2.0e-18	86.1	COG0670	Integral membrane protein, interacts with FtsH	233
644916688	719	26.6	31	651	105	631	7.0e-88	318	COG0209	Ribonucleotide reductase alpha subunit	696
644916689	160	20.61	1	158	3	160	7.0e-14	69.9	COG3157	Type VI protein secretion system component Hcp (secreted cytotoxin)	162
644916690	664	37.84	3	546	5	550	0.0e+00	501	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
644916692	326	29.94	4	312	3	325	1.0e-47	183	COG5351	Uncharacterized protein	367
644916700	371	33.9	1	354	1	322	5.0e-62	232	COG3520	Predicted component of the type VI protein secretion system	335
644916701	611	38.02	1	611	1	621	0.0e+00	524	COG3519	Type VI protein secretion system component VasA	621
644916702	165	33.33	5	160	2	154	6.0e-22	96.9	COG3518	Predicted component of the type VI protein secretion system	157
644916703	478	43.52	43	474	68	490	0.0e+00	482	COG3517	Predicted component of the type VI protein secretion system	495
644916705	498	52.41	4	497	3	493	0.0e+00	656	COG3517	Predicted component of the type VI protein secretion system	495
644916706	173	44.91	3	169	2	168	2.0e-43	168	COG3516	Predicted component of the type VI protein secretion system	169
644916707	373	28.37	15	359	10	335	8.0e-22	98.2	COG3515	Predicted component of the type VI protein secretion system	346
644916708	545	22.92	215	538	109	429	5.0e-34	139	COG3456	Predicted component of the type VI protein secretion system, contains a FHA domain	430
644916709	162	29.63	1	162	1	156	5.0e-21	93.8	COG3521	Predicted component of the type VI protein secretion system	159
644916710	444	45.74	1	444	1	446	0.0e+00	487	COG3522	Predicted component of the type VI protein secretion system	446
644916711	302	37.15	36	288	7	259	4.0e-56	212	COG3455	Type VI protein secretion system component VasF	262
644916712	1177	32.58	17	1132	18	1148	0.0e+00	703	COG3523	Type VI protein secretion system component VasK	1188
644916713	254	29.33	7	231	9	217	3.0e-26	112	COG3913	Uncharacterized protein	227
644916714	249	40.24	8	243	5	250	2.0e-52	199	COG0631	Serine/threonine protein phosphatase PrpC	262
644916715	597	26.69	161	479	2	327	1.0e-31	131	COG0515	Serine/threonine protein kinase	384
644916718	205	26.9	7	202	16	209	2.0e-19	88.9	COG0811	Biopolymer transport protein ExbB/TolQ	216
644916720	165	18.83	12	163	6	136	8.0e-08	50.2	COG0848	Biopolymer transport protein ExbD	137
644916724	687	28.42	419	598	66	254	1.0e-26	115	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
644916726	685	30.53	411	590	66	254	1.0e-27	118	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
644916733	192	27.59	3	169	11	176	2.0e-15	76	COG1678	Putative transcriptional regulator, AlgH/UPF0301 family	194
644916737	416	21.57	24	372	35	388	4.0e-11	62.9	COG2814	Predicted arabinose efflux permease, MFS family	394
644916743	636	22.56	149	636	100	554	4.0e-42	166	COG2831	Hemolysin activation/secretion protein	554
644916744	507	26.69	13	507	13	529	9.0e-48	185	COG0578	Glycerol-3-phosphate dehydrogenase	532
644916746	461	26.96	14	456	8	460	4.0e-34	139	COG0471	Di- and tricarboxylate transporter	461
644916747	106	30.85	10	102	1	94	2.0e-11	60.8	COG5626	Uncharacterized protein	97
644916748	827	36.19	4	827	7	829	0.0e+00	569	COG3127	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component	829
644916749	227	60.63	1	219	6	226	6.0e-73	267	COG4181	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component	228
644916750	223	27.75	37	223	6	212	7.0e-20	90.7	COG2755	Lysophospholipase L1 or related esterase	216
644916752	1070	52.83	1	492	1	487	0.0e+00	521	COG1530	Ribonuclease G or E	487
644916753	314	40	5	300	1	289	3.0e-72	265	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
644916754	212	32.55	1	209	5	216	5.0e-37	147	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
644916756	632	44.8	1	517	3	527	0.0e+00	522	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
644916757	215	36.32	24	212	2	189	8.0e-49	186	COG0424	Predicted house-cleaning NTP pyrophosphatase, Maf/HAM1 superfamily	193
644916758	188	29.38	10	182	6	175	8.0e-13	66.9	COG1399	Uncharacterized metal-binding protein YceD, DUF177 family	176
644916759	60	47.37	1	56	1	57	2.0e-12	64.1	COG0333	Ribosomal protein L32	57
644916760	330	42.42	5	330	2	331	5.0e-92	331	COG0416	Fatty acid/phospholipid biosynthesis enzyme	338
644916761	323	53.67	4	315	2	308	1.0e-93	336	COG0331	Malonyl CoA-acyl carrier protein transacylase	310
644916762	247	44.27	1	244	1	250	3.0e-49	188	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
644916764	79	70.89	1	79	2	80	2.0e-10	57.6	COG0236	Acyl carrier protein	80
644916765	410	56.42	2	410	1	411	0.0e+00	487	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
644916766	290	27.02	6	288	1	284	4.0e-34	138	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
644916767	358	38.94	1	336	4	342	5.0e-93	334	COG1559	Cell division protein YceG, involved in septum cleavage	342
644916768	205	45.15	1	205	1	205	3.0e-56	211	COG0125	Thymidylate kinase	208
644916769	208	38.53	2	208	76	289	1.0e-49	189	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
644916771	117	63.06	9	117	8	117	5.0e-41	159	COG3215	Tfp pilus assembly protein PilZ	117
644916772	264	48.06	1	255	2	255	3.0e-77	282	COG0084	Tat protein secretion system quality control protein TatD (DNase activity)	256
644916774	327	33.13	5	326	1	312	8.0e-65	240	COG0039	Malate/lactate dehydrogenase	313
644916775	158	56.77	1	155	1	154	1.0e-54	205	COG1225	Peroxiredoxin	157
644916776	330	30.77	227	329	23	125	1.0e-14	73.7	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
644916777	111	41.67	15	110	1	96	2.0e-22	98	COG1862	Preprotein translocase subunit YajC	97
644916779	348	38.55	6	336	5	323	4.0e-71	262	COG2515	1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase, PLP-dependent ACC family	323
644916780	443	52.71	1	437	4	443	0.0e+00	474	COG1115	Na+/alanine symporter	452
644916782	319	27.7	1	294	6	295	5.0e-36	145	COG0583	DNA-binding transcriptional regulator, LysR family	297
644916784	236	43.64	6	236	14	242	1.0e-58	219	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
644916785	205	26.8	1	181	5	197	9.0e-21	93.5	COG0560	Phosphoserine phosphatase	212
644916787	314	38.64	21	144	21	151	4.0e-21	95.7	COG2153	Predicted N-acyltransferase, GNAT family	155
644916788	385	50.18	11	289	9	285	4.0e-78	285	COG2850	Ribosomal protein L16 Arg81 hydroxylase, contains JmjC domain	383
644916789	459	30.48	12	456	1	436	4.0e-108	385	COG0015	Adenylosuccinate lyase	438
644916790	207	41.46	3	206	2	206	1.0e-51	196	COG2915	Regulator of phage lambda lysogenization HflD, binds to CII and stimulates its degradation	207
644916791	367	56.2	7	366	1	356	0.0e+00	484	COG0482	tRNA U34 2-thiouridine synthase MnmA/TrmU, contains the PP-loop ATPase domain	356
644916792	349	35.1	49	347	7	297	8.0e-50	191	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
644916795	418	44.31	8	416	4	407	4.0e-98	351	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
644916796	228	47.77	5	227	1	224	2.0e-70	258	COG1136	ABC-type lipoprotein export system, ATPase component	226
644916797	409	35.99	1	409	3	408	1.0e-85	310	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
644916798	355	31.45	19	321	13	292	8.0e-33	134	COG4974	Site-specific recombinase XerD	300
644916811	169	27.88	5	169	43	204	3.0e-27	114	COG2941	Demethoxyubiquinone hydroxylase, CLK1/Coq7/Cat5 family	204
644916820	268	29.79	33	267	12	228	1.0e-10	60.4	COG2801	Transposase InsO and inactivated derivatives	232
644916827	268	29.79	33	267	12	228	1.0e-10	60.4	COG2801	Transposase InsO and inactivated derivatives	232
644916843	479	37.19	36	153	34	151	5.0e-10	59.7	COG3666	Transposase	161
644916844	156	21.66	1	153	12	157	1.0e-07	49.2	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
644916849	219	19.56	7	219	4	215	5.0e-14	71.3	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
644916850	453	20.05	41	422	53	432	1.0e-13	71.8	COG2271	Sugar phosphate permease	448
644916852	542	24.21	14	508	2	467	3.0e-53	203	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
644916853	307	44.57	134	306	7	180	5.0e-41	161	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
644916856	541	30	9	136	5	130	2.0e-09	57.9	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
644916858	973	36.18	12	970	6	968	0.0e+00	734	COG1026	Zn-dependent peptidase, M16 (insulinase) family	978
644916862	427	39.55	248	421	4	180	8.0e-39	155	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
644916865	503	31.02	134	486	4	337	1.0e-57	217	COG0469	Pyruvate kinase	477
644916866	306	40.53	8	300	2	295	5.0e-49	188	COG1575	1,4-dihydroxy-2-naphthoate octaprenyltransferase	303
644916867	223	47.89	10	222	2	211	4.0e-62	231	COG1515	Deoxyinosine 3'endonuclease (endonuclease V)	212
644916881	415	22.63	45	364	19	344	1.0e-27	117	COG2206	HD-GYP domain, c-di-GMP phosphodiesterase class II (or its inactivated variant)	344
644916882	485	35.97	231	482	97	332	8.0e-42	165	COG0642	Signal transduction histidine kinase	336
644916883	94	61.29	1	92	1	93	5.0e-29	119	COG3123	Uncharacterized conserved protein YaiE, UPF0345 family	94
644916884	95	50.59	2	84	3	87	2.0e-18	83.7	COG2257	Type III secretion system substrate exporter, FlhB-like	92
644916886	233	50.7	20	226	3	207	3.0e-56	211	COG4133	ABC-type transport system involved in cytochrome c biogenesis, ATPase component	209
644916887	229	52.36	16	227	9	220	1.0e-38	153	COG2386	ABC-type transport system involved in cytochrome c biogenesis, permease component	221
644916888	247	37.92	1	239	33	272	4.0e-34	138	COG0755	ABC-type transport system involved in cytochrome c biogenesis, permease component	281
644916889	61	32.69	7	58	3	54	9.0e-06	41.8	COG3114	Heme exporter protein D	67
644916890	155	44.44	1	153	1	153	2.0e-45	174	COG2332	Cytochrome c-type biogenesis protein CcmE	153
644916891	677	51.46	1	648	1	648	0.0e+00	623	COG1138	Cytochrome c biogenesis factor	648
644916892	173	27.56	31	153	3	127	4.0e-12	64.5	COG0526	Thiol-disulfide isomerase or thioredoxin	127
644916893	339	30.81	5	338	15	343	4.0e-64	238	COG2957	Agmatine/peptidylarginine deiminase	346
644916894	305	33.33	5	300	3	274	1.0e-47	183	COG0388	Predicted amidohydrolase	274
644916895	441	58.21	1	414	1	407	0.0e+00	588	COG4553	Poly-beta-hydroxyalkanoate depolymerase	415
644916901	160	42.31	3	130	2	130	8.0e-33	133	COG3088	Cytochrome c-type biogenesis protein CcmH/NrfF	153
644916902	422	28.86	3	300	1	287	2.0e-30	126	COG4235	Cytochrome c-type biogenesis protein CcmH/NrfG	287
644916903	1166	34.82	1	1164	1	1163	0.0e+00	605	COG1196	Chromosome segregation ATPase	1163
644916904	326	27.79	1	320	4	322	1.0e-38	154	COG3115	Cell division protein ZipA, interacts with FtsZ	324
644916905	676	57.4	7	674	3	667	0.0e+00	924	COG0272	NAD-dependent DNA ligase	667
644916906	201	45.45	1	194	1	197	2.0e-55	208	COG4764	Uncharacterized protein	197
644916909	350	34.65	246	345	23	122	7.0e-15	74.9	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
644916912	594	32.33	36	461	6	392	6.0e-70	258	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
644916913	537	34.01	1	531	6	522	8.0e-120	424	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
644916914	306	38.59	6	296	4	291	2.0e-45	176	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
644916915	148	36.62	6	147	2	140	6.0e-21	93.4	COG1585	Membrane protein implicated in regulation of membrane protease activity	140
644916916	381	25	5	368	13	305	2.0e-24	106	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
644916921	877	77.07	5	862	2	848	0.0e+00	1427	COG1049	Aconitase B	852
644916923	147	37.5	5	60	5	59	1.0e-10	59.2	COG3313	Predicted Fe-S protein YdhL, DUF1289 family	74
644916924	201	58.16	3	198	6	201	2.0e-64	238	COG4445	tRNA isopentenyl-2-thiomethyl-A-37 hydroxylase MiaE (synthesis of 2-methylthio-cis-ribozeatin)	203
644916925	432	18.89	15	367	5	321	3.0e-14	73.6	COG0687	Spermidine/putrescine-binding periplasmic protein	363
644916926	620	40.73	336	609	68	329	9.0e-41	162	COG0642	Signal transduction histidine kinase	336
644916927	241	43.75	5	241	1	236	2.0e-57	215	COG2908	UDP-2,3-diacylglucosamine pyrophosphatase LpxH	237
644916928	163	47.88	1	163	1	157	1.0e-51	195	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
644916929	548	31.17	18	528	1	472	3.0e-102	365	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
644916930	458	53.45	2	457	1	463	0.0e+00	609	COG0215	Cysteinyl-tRNA synthetase	464
644916933	718	33.54	390	710	35	336	3.0e-44	173	COG0642	Signal transduction histidine kinase	336
644916934	312	38.74	5	304	1	283	2.0e-59	222	COG3001	Fructosamine-3-kinase	286
644916935	265	28.35	67	260	1	174	4.0e-19	88.9	COG1076	DnaJ-domain-containing proteins 1	174
644916937	69	55.22	4	69	1	67	3.0e-19	86.3	COG1278	Cold shock protein, CspA family	67
644916941	263	18.58	14	255	25	267	2.0e-10	60	COG0421	Spermidine synthase	282
644916942	90	36.14	2	82	14	96	3.0e-13	66.9	COG0607	Rhodanese-related sulfurtransferase	110
644916943	342	33.71	75	340	38	296	9.0e-41	161	COG2813	16S rRNA G1207 methylase RsmC	300
644916944	238	38.11	1	235	3	241	3.0e-53	202	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
644916945	280	56.12	5	278	2	279	8.0e-93	333	COG0190	5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase	283
644916949	527	28.79	132	527	18	408	8.0e-38	152	COG0840	Methyl-accepting chemotaxis protein	408
644916951	360	30.35	67	312	3	247	3.0e-38	152	COG2220	L-ascorbate metabolism protein UlaG, beta-lactamase superfamily	258
644916952	471	37.16	16	451	1	413	6.0e-109	388	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
644916953	164	33.77	15	164	13	162	6.0e-26	110	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
644916955	141	26.43	7	138	9	146	4.0e-08	50.9	COG5404	Cell division inhibitor SulA, prevents FtsZ ring assembly	169
644916956	200	49.75	1	199	1	199	3.0e-53	201	COG1974	SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase)	201
644916959	343	40.73	1	297	1	293	2.0e-68	253	COG1472	Periplasmic beta-glucosidase and related glycosidases	397
644916960	369	26.94	69	362	12	302	3.0e-34	139	COG0668	Small-conductance mechanosensitive channel	316
644916962	72	49.28	4	72	1	67	2.0e-18	84.4	COG1278	Cold shock protein, CspA family	67
644916964	1157	48.61	8	1155	1	1135	0.0e+00	1376	COG1197	Transcription-repair coupling factor (superfamily II helicase)	1139
644916965	445	60.63	1	445	1	447	0.0e+00	611	COG1726	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrA	447
644916966	401	59.6	4	398	2	400	4.0e-121	428	COG1805	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrB	400
644916967	258	49.62	3	258	6	261	6.0e-84	303	COG2869	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrC	264
644916968	219	67.98	2	204	6	208	6.0e-81	293	COG1347	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrD	208
644916969	202	75.74	1	202	1	198	5.0e-73	267	COG2209	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrE	198
644916970	407	72.17	4	407	5	410	0.0e+00	708	COG2871	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrF	410
644916971	352	44.81	14	348	3	335	2.0e-93	336	COG1477	Thiamine biosynthesis lipoprotein ApbE	337
644916972	80	37.5	1	72	1	68	3.0e-13	66.5	COG2991	Uncharacterized protein	77
644916973	465	35.59	3	455	2	454	1.0e-112	400	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
644916976	742	70.75	1	742	1	742	0.0e+00	1199	COG2838	Monomeric isocitrate dehydrogenase	744
644916977	95	58.21	1	67	1	67	2.0e-24	104	COG1278	Cold shock protein, CspA family	67
644916978	124	53.33	12	116	1	105	9.0e-33	132	COG2127	ATP-dependent Clp protease adapter protein ClpS	107
644916979	766	46.16	1	750	1	782	0.0e+00	859	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
644916980	72	68.06	1	72	1	72	2.0e-24	104	COG0361	Translation initiation factor IF-1	75
644916981	243	43.28	1	233	4	241	4.0e-72	264	COG2935	Arginyl-tRNA--protein-N-Asp/Glu arginylyltransferase	253
644916982	259	53.92	14	217	3	205	6.0e-72	264	COG2360	Leu/Phe-tRNA-protein transferase	221
644916983	316	50.48	4	315	1	303	4.0e-92	331	COG0492	Thioredoxin reductase	305
644916985	211	31.16	1	210	1	211	3.0e-29	121	COG2834	Outer membrane lipoprotein-sorting protein	211
644916986	447	55.89	7	438	3	433	0.0e+00	590	COG2256	Replication-associated recombination protein RarA (DNA-dependent ATPase)	436
644916987	124	41.94	1	123	2	125	3.0e-19	87.1	COG0239	Fluoride ion exporter CrcB/FEX, affects chromosome condensation	126
644916988	426	58.84	1	426	1	428	0.0e+00	569	COG0172	Seryl-tRNA synthetase	429
644916989	459	55.14	215	457	3	243	6.0e-89	321	COG0007	Uroporphyrinogen-III methylase (siroheme synthase)	244
644916990	461	40.87	6	457	3	454	1.0e-121	430	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
644916991	414	22.63	46	394	13	281	2.0e-11	64.1	COG4974	Site-specific recombinase XerD	300
644916992	222	27.66	82	221	23	157	7.0e-21	94.4	COG2030	Acyl dehydratase	159
644916993	472	30.65	1	432	2	444	5.0e-44	172	COG0591	Na+/proline symporter	493
644916995	341	48.25	1	341	9	340	7.0e-85	307	COG0798	Arsenite efflux pump ArsB, ACR3 family	342
644916996	158	33.57	1	135	3	136	3.0e-27	114	COG0394	Protein-tyrosine-phosphatase	139
644916997	117	27.96	14	106	12	104	3.0e-09	54	COG0640	DNA-binding transcriptional regulator, ArsR family	110
644916998	1039	48.6	1	1036	1	1027	0.0e+00	1174	COG3696	Cu/Ag efflux pump CusA	1027
644916999	486	25.08	84	385	52	361	4.0e-23	102	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
644917002	5303	32.47	1	876	4	855	0.0e+00	579	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
644917003	331	27.73	1	324	1	312	1.0e-36	147	COG0451	Nucleoside-diphosphate-sugar epimerase	314
644917004	411	32.38	58	405	39	385	1.0e-79	290	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
644917006	608	41.78	1	282	2	293	1.0e-72	267	COG0331	Malonyl CoA-acyl carrier protein transacylase	310
644917007	845	23.62	228	831	146	727	8.0e-61	229	COG1033	Predicted exporter protein, RND superfamily	727
644917009	6813	37.99	4072	4727	1	642	6.0e-127	452	COG1020	Non-ribosomal peptide synthetase component F	642
644917010	374	23.95	138	374	47	281	1.0e-13	71.1	COG0842	ABC-type multidrug transport system, permease component	286
644917012	437	34.78	1	415	15	445	2.0e-101	363	COG0160	4-aminobutyrate aminotransferase or related aminotransferase	447
644917014	680	15.25	22	642	45	737	1.0e-13	71.9	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
644917015	557	31.02	19	291	62	327	9.0e-37	148	COG0642	Signal transduction histidine kinase	336
644917020	463	36.97	7	457	11	474	1.0e-98	353	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
644917023	470	36.05	6	441	1	432	8.0e-72	264	COG2233	Xanthine/uracil permease	451
644917024	98	35.42	1	96	2	96	5.0e-20	89.2	COG5470	Uncharacterized conserved protein, DUF1330 family	96
644917025	327	26.91	27	321	2	267	7.0e-31	128	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
644917026	469	28.52	166	426	84	333	9.0e-25	108	COG1816	Adenosine deaminase	345
644917027	789	16.36	10	789	12	768	3.0e-21	97.7	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
644917029	450	22.89	259	444	11	211	2.0e-22	100	COG0811	Biopolymer transport protein ExbB/TolQ	216
644917030	170	20.32	13	169	18	204	3.0e-15	74.6	COG0811	Biopolymer transport protein ExbB/TolQ	216
644917031	136	28.8	10	133	10	133	5.0e-17	80.3	COG0848	Biopolymer transport protein ExbD	137
644917034	362	37.43	5	358	11	347	7.0e-78	284	COG5042	Purine nucleoside permease	349
644917035	533	32.12	1	525	14	536	4.0e-97	349	COG0405	Gamma-glutamyltranspeptidase	539
644917036	272	23.99	3	268	2	254	8.0e-06	44.6	COG0730	Uncharacterized membrane protein YfcA	258
644917037	408	37.34	10	407	2	381	3.0e-103	369	COG0075	Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism protein PucG	383
644917038	418	23.34	35	415	19	403	1.0e-36	147	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
644917039	250	38.67	1	250	2	250	5.0e-46	177	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
644917040	134	24.81	3	132	2	130	3.0e-14	71.1	COG2764	Uncharacterized conserved protein PhnB, glyoxalase superfamily	136
644917044	191	42.04	37	184	1	151	5.0e-38	150	COG3865	Glyoxalase superfamily enzyme, possibly 3-demethylubiquinone-9 3-methyltransferase	151
644917045	375	19.21	1	350	3	362	1.0e-22	101	COG1680	CubicO group peptidase, beta-lactamase class C family	390
644917046	153	31.08	5	148	24	171	2.0e-21	95.6	COG0634	Hypoxanthine-guanine phosphoribosyltransferase	178
644917047	140	26.85	19	125	1	106	2.0e-21	95.1	COG3791	Uncharacterized conserved protein	133
644917052	803	17.2	79	803	37	768	3.0e-28	120	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
644917053	357	30.25	21	295	1	263	4.0e-47	182	COG0523	GTPase, G3E family	323
644917055	134	41.28	1	102	1	109	2.0e-13	68.2	COG0789	DNA-binding transcriptional regulator, MerR family	124
644917057	270	28.62	1	269	2	258	2.0e-10	59.6	COG0730	Uncharacterized membrane protein YfcA	258
644917061	431	39.68	1	430	1	403	1.0e-100	360	COG3748	Uncharacterized membrane protein	407
644917062	432	28.5	28	429	20	408	4.0e-71	262	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
644917063	114	38.26	9	114	11	124	6.0e-22	96.1	COG2351	5-hydroxyisourate hydrolase (purine catabolism), transthyretin-related family	124
644917064	163	28.92	1	160	6	171	2.0e-11	62.2	COG3195	2-oxo-4-hydroxy-4-carboxy--5-ureidoimidazoline (OHCU) decarboxylase	176
644917065	280	28.4	5	253	1	255	1.0e-36	147	COG1975	Xanthine and CO dehydrogenase maturation factor, XdhC/CoxF family	278
644917066	784	57.42	18	776	21	781	0.0e+00	1012	COG4631	Xanthine dehydrogenase, molybdopterin-binding subunit B	781
644917067	484	43.27	1	467	9	481	2.0e-127	449	COG4630	Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A	493
644917069	243	22.66	32	232	5	199	1.0e-12	67	COG1309	DNA-binding transcriptional regulator, AcrR family	201
644917070	449	33.41	1	427	2	414	9.0e-67	248	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
644917071	353	38.81	7	353	12	349	1.0e-77	283	COG5042	Purine nucleoside permease	349
644917072	191	22.64	1	159	2	145	2.0e-13	69.2	COG2236	Hypoxanthine phosphoribosyltransferase	192
644917073	431	56.35	1	431	3	435	7.0e-116	411	COG2252	Xanthine/uracil/vitamin C permease, AzgA family	436
644917074	288	19.03	27	223	7	230	4.0e-10	59.1	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
644917076	727	65.16	1	727	8	729	0.0e+00	1118	COG0376	Catalase (peroxidase I)	730
644917077	334	46.96	30	317	47	359	3.0e-89	321	COG1858	Cytochrome c peroxidase	364
644917079	317	29.49	82	292	1	200	2.0e-26	113	COG0625	Glutathione S-transferase	211
644917081	708	48.43	51	707	18	682	0.0e+00	763	COG0339	Zn-dependent oligopeptidase	683
644917084	313	31.54	166	311	5	153	1.0e-18	87.2	COG3449	DNA gyrase inhibitor GyrI	154
644917085	401	37.69	9	390	73	459	2.0e-80	293	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
644917086	1036	46.18	1	1033	1	1020	0.0e+00	1113	COG3696	Cu/Ag efflux pump CusA	1027
644917090	442	20.2	40	442	4	388	9.0e-34	138	COG3550	Serine/threonine protein kinase HipA, toxin component of the HipAB toxin-antitoxin module	392
644917092	507	51.77	1	504	3	505	0.0e+00	640	COG3046	Uncharacterized protein related to deoxyribodipyrimidine photolyase	505
644917093	772	38.35	1	741	13	751	0.0e+00	602	COG4412	Bacillopeptidase F, M6 metalloprotease family	760
644917095	201	26.02	1	182	1	195	1.0e-20	93	COG1011	FMN phosphatase YigB, HAD superfamily	229
644917096	592	17.98	107	562	148	588	1.0e-09	58.4	COG1164	Oligoendopeptidase F	598
644917097	586	31.79	7	586	13	498	5.0e-91	328	COG3104	Dipeptide/tripeptide permease	498
644917098	535	53.63	1	533	3	535	0.0e+00	675	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
644917099	298	46.88	12	297	1	288	1.0e-73	269	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
644917100	309	46.37	1	306	1	316	4.0e-84	304	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
644917101	542	36.14	5	536	12	559	3.0e-111	395	COG4166	ABC-type oligopeptide transport system, periplasmic component	562
644917102	548	33.04	1	545	4	557	7.0e-98	351	COG4166	ABC-type oligopeptide transport system, periplasmic component	562
644917104	532	31.53	348	456	1	110	1.0e-11	65.3	COG1388	LysM repeat	124
644917105	261	29.73	1	226	12	248	6.0e-20	91.5	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
644917107	147	65.97	1	141	1	144	2.0e-51	194	COG0328	Ribonuclease HI	154
644917108	239	36.55	1	236	13	242	1.0e-46	179	COG0847	DNA polymerase III, epsilon subunit or related 3'-5' exonuclease	243
644917109	502	67.61	1	496	1	496	0.0e+00	687	COG3067	Na+/H+ antiporter NhaB	516
644917111	262	42.28	15	256	23	268	1.0e-63	236	COG2816	NADH pyrophosphatase NudC, Nudix superfamily	279
644917113	353	30.75	34	344	1	309	9.0e-47	181	COG0616	Periplasmic serine protease, ClpP class	317
644917114	388	28	5	367	7	380	2.0e-27	116	COG4651	Predicted Kef-type K+ transport protein, K+/H+ antiporter domain	408
644917115	164	35.54	1	164	3	166	3.0e-31	127	COG3749	Uncharacterized conserved protein, DUF934 family	167
644917116	554	34.65	1	549	1	510	0.0e+00	479	COG0155	Sulfite reductase, beta subunit (hemoprotein)	510
644917120	1229	57.62	330	1195	1	842	0.0e+00	1152	COG1410	Methionine synthase I, cobalamin-binding domain	842
644917121	194	36.56	101	192	1	93	5.0e-22	97.7	COG0694	Fe-S cluster biogenesis protein NfuA, 4Fe-4S-binding domain	93
644917123	355	57.76	1	348	2	348	0.0e+00	529	COG0722	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase	351
644917127	289	42.7	8	285	11	286	3.0e-71	262	COG1946	Acyl-CoA thioesterase	289
644917129	548	30.04	8	462	1	396	2.0e-67	250	COG0644	Dehydrogenase (flavoprotein)	396
644917130	250	46.92	1	249	1	260	2.0e-68	252	COG2086	Electron transfer flavoprotein, alpha and beta subunits	260
644917131	309	51.11	1	309	1	310	7.0e-82	297	COG2025	Electron transfer flavoprotein, alpha subunit	313
644917132	712	19.93	126	414	39	325	1.0e-08	55.6	COG0642	Signal transduction histidine kinase	336
644917133	273	42.59	6	273	4	261	1.0e-78	286	COG0708	Exonuclease III	261
644917134	701	35.44	151	560	22	390	1.0e-77	284	COG0793	C-terminal processing protease CtpA/Prc, contains a PDZ domain	406
644917136	208	21.65	6	198	12	201	5.0e-11	61.2	COG1309	DNA-binding transcriptional regulator, AcrR family	201
644917137	389	29.84	1	378	1	370	3.0e-32	132	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
644917138	1059	45.24	2	1039	1	1009	0.0e+00	987	COG0841	Multidrug efflux pump subunit AcrB	1009
644917142	267	41.2	3	267	13	278	7.0e-79	287	COG0656	Aldo/keto reductase, related to diketogulonate reductase	280
644917143	355	39.57	1	354	3	358	4.0e-89	321	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
644917145	341	30.7	1	339	1	325	7.0e-55	207	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
644917146	274	25	5	265	15	282	2.0e-31	129	COG1639	HD-like signal output (HDOD) domain, no enzymatic activity	289
644917148	345	24.71	4	339	2	312	1.0e-33	137	COG0451	Nucleoside-diphosphate-sugar epimerase	314
644917149	259	34.74	159	253	23	117	9.0e-16	77.6	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
644917151	401	26.21	40	381	43	365	1.0e-32	134	COG1680	CubicO group peptidase, beta-lactamase class C family	390
644917160	243	26.12	1	229	3	242	5.0e-20	91.4	COG0388	Predicted amidohydrolase	274
644917161	184	37.71	15	183	5	179	2.0e-28	118	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
644917170	268	29.79	33	267	12	228	8.0e-11	61.2	COG2801	Transposase InsO and inactivated derivatives	232
644917175	519	27.74	2	153	1	151	2.0e-14	74	COG3666	Transposase	161
644917179	234	34.72	1	215	1	202	7.0e-37	147	COG1182	FMN-dependent NADH-azoreductase	202
644917180	290	23.29	11	290	2	293	3.0e-25	109	COG0583	DNA-binding transcriptional regulator, LysR family	297
644917183	287	39.65	6	281	7	291	8.0e-61	227	COG0331	Malonyl CoA-acyl carrier protein transacylase	310
644917188	377	29.33	6	341	1	334	7.0e-41	161	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
644917189	268	34.05	18	248	4	234	6.0e-41	161	COG3208	Surfactin synthase thioesterase subunit	244
644917190	455	21.41	15	375	7	336	3.0e-31	130	COG2070	NAD(P)H-dependent flavin oxidoreductase YrpB, nitropropane dioxygenase family	336
644917191	151	28.24	60	144	9	92	9.0e-09	53	COG4891	Uncharacterized protein	93
644917194	378	27.42	252	375	2	119	7.0e-13	68.7	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
644917206	606	17.87	15	360	9	343	9.0e-22	98.9	COG3500	Phage protein D	350
644917207	145	23.02	14	139	1	115	2.0e-14	71.5	COG3628	Phage baseplate assembly protein W	116
644917216	208	26.47	1	204	1	201	6.0e-10	57.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
644917217	314	25.39	3	258	22	270	7.0e-26	111	COG1566	Multidrug resistance efflux pump	352
644917218	308	36.54	4	299	3	292	7.0e-72	264	COG1131	ABC-type multidrug transport system, ATPase component	293
644917219	375	34.65	172	372	80	281	1.0e-19	91.1	COG0842	ABC-type multidrug transport system, permease component	286
644917220	3228	33.56	3071	3219	39	187	8.0e-26	114	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
644917221	307	31.29	11	300	2	288	2.0e-32	133	COG0583	DNA-binding transcriptional regulator, LysR family	297
644917222	361	29.97	45	361	4	299	2.0e-31	130	COG1073	Fermentation-respiration switch protein FrsA, has esterase activity, DUF1100 family	299
644917223	132	35.43	1	126	6	131	8.0e-19	86	COG1917	Cupin domain protein related to quercetin dioxygenase	131
644917228	636	24.68	206	584	33	414	3.0e-16	80.7	COG0471	Di- and tricarboxylate transporter	461
644917230	864	22.69	35	408	10	345	3.0e-25	110	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
644917231	298	25.63	1	270	1	273	2.0e-24	106	COG0583	DNA-binding transcriptional regulator, LysR family	297
644917232	642	26.44	9	612	10	529	1.0e-68	254	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
644917233	302	30.98	12	301	1	280	1.0e-49	190	COG1398	Fatty-acid desaturase	289
644917235	339	31.71	51	335	19	288	3.0e-52	198	COG1398	Fatty-acid desaturase	289
644917239	575	45.09	6	575	5	569	0.0e+00	502	COG3263	NhaP-type Na+/H+ and K+/H+ antiporter with C-terminal TrkAC and CorC domains	574
644917242	407	36.97	5	375	1	323	3.0e-84	305	COG0523	GTPase, G3E family	323
644917245	244	35.63	3	241	5	251	6.0e-59	220	COG1121	ABC-type Mn2+/Zn2+ transport system, ATPase component	254
644917246	288	38.63	3	278	2	274	5.0e-42	164	COG1108	ABC-type Mn2+/Zn2+ transport system, permease component	274
644917247	295	36.21	1	295	3	302	7.0e-66	244	COG0803	ABC-type Zn uptake system ZnuABC, Zn-binding component ZnuA	303
644917249	215	30.82	56	214	28	163	1.0e-24	106	COG3495	Uncharacterized protein	166
644917250	283	45.28	50	259	2	210	8.0e-60	224	COG1136	ABC-type lipoprotein export system, ATPase component	226
644917251	408	18.9	5	402	14	396	2.0e-10	60.7	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
644917256	244	42.6	5	225	1	222	6.0e-65	240	COG1136	ABC-type lipoprotein export system, ATPase component	226
644917257	814	17.05	487	805	73	418	5.0e-09	57.1	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
644917258	656	18.45	152	518	80	417	3.0e-12	67.7	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
644917259	305	34.7	1	266	2	263	1.0e-54	207	COG1131	ABC-type multidrug transport system, ATPase component	293
644917261	62	60.38	8	60	13	65	3.0e-18	83.2	COG3251	Uncharacterized conserved protein YbdZ, MbtH family	71
644917262	659	29.7	10	549	13	528	8.0e-76	278	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
644917263	410	24.88	16	408	26	409	8.0e-38	151	COG2124	Cytochrome P450	411
644917266	4860	31.13	1385	2035	1	642	1.0e-111	400	COG1020	Non-ribosomal peptide synthetase component F	642
644917268	2979	26.83	1704	2345	1	641	2.0e-88	323	COG1020	Non-ribosomal peptide synthetase component F	642
644917270	1301	31.87	72	718	1	642	8.0e-109	389	COG1020	Non-ribosomal peptide synthetase component F	642
644917273	631	17.63	113	513	60	472	2.0e-14	75	COG1032	Radical SAM superfamily enzyme YgiQ, UPF0313 family	490
644917275	73	50.75	5	71	1	66	9.0e-16	75.2	COG1476	DNA-binding transcriptional regulator, XRE-family HTH domain	68
644917279	1365	29.7	510	1151	1	641	2.0e-102	368	COG1020	Non-ribosomal peptide synthetase component F	642
644917280	2963	39.24	9	885	6	880	0.0e+00	706	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
644917281	237	31.8	1	237	2	239	2.0e-38	152	COG2186	DNA-binding transcriptional regulator, FadR family	241
644917283	354	48.65	10	338	1	329	2.0e-95	343	COG1085	Galactose-1-phosphate uridylyltransferase	338
644917284	389	47.18	16	382	15	386	3.0e-110	391	COG0153	Galactokinase	390
644917285	568	31.99	1	565	1	520	2.0e-68	254	COG4146	Uncharacterized membrane permease YidK, sodium:solute symporter family	571
644917286	648	32.34	304	608	38	343	5.0e-53	202	COG3867	Arabinogalactan endo-1,4-beta-galactosidase	403
644917289	520	25.91	55	520	2	427	3.0e-66	246	COG3664	Beta-xylosidase	428
644917290	799	25.53	510	793	84	405	2.0e-31	131	COG4677	Pectin methylesterase and related acyl-CoA thioesterases	405
644917291	345	32.85	8	341	4	349	4.0e-64	238	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
644917292	277	35.97	6	252	1	250	5.0e-47	181	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
644917293	280	21.03	1	255	1	268	3.0e-18	85.9	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
644917295	672	15.57	428	664	4	212	6.0e-07	49.9	COG2755	Lysophospholipase L1 or related esterase	216
644917296	688	21.08	461	680	5	212	3.0e-14	73.8	COG2755	Lysophospholipase L1 or related esterase	216
644917300	417	23.08	214	409	4	204	1.0e-15	77.7	COG2755	Lysophospholipase L1 or related esterase	216
644917301	542	28.2	46	528	4	531	2.0e-75	276	COG3507	Beta-xylosidase	549
644917302	531	23.3	249	452	4	203	1.0e-19	91.4	COG2220	L-ascorbate metabolism protein UlaG, beta-lactamase superfamily	258
644917303	4025	39.33	1388	2037	1	642	0.0e+00	495	COG1020	Non-ribosomal peptide synthetase component F	642
644917304	2685	39.33	308	957	1	642	0.0e+00	480	COG1020	Non-ribosomal peptide synthetase component F	642
644917305	2214	40.64	1368	2014	1	639	0.0e+00	491	COG1020	Non-ribosomal peptide synthetase component F	642
644917306	4249	34.71	3387	4060	1	641	6.0e-128	454	COG1020	Non-ribosomal peptide synthetase component F	642
644917307	3718	37.22	1784	2444	1	642	0.0e+00	494	COG1020	Non-ribosomal peptide synthetase component F	642
644917308	561	37.23	5	558	7	543	2.0e-114	406	COG4615	ABC-type siderophore export system, fused ATPase and permease components	546
644917309	322	15.94	52	318	41	272	9.0e-06	44.6	COG2175	Taurine dioxygenase, alpha-ketoglutarate-dependent	286
644917312	5068	36.3	3709	4375	1	642	5.0e-124	441	COG1020	Non-ribosomal peptide synthetase component F	642
644917313	862	25.13	284	842	193	725	6.0e-57	216	COG1033	Predicted exporter protein, RND superfamily	727
644917314	438	28.57	9	425	26	438	3.0e-55	209	COG4325	Uncharacterized membrane protein	464
644917317	125	31.93	2	118	6	119	1.0e-12	65.5	COG4994	Uncharacterized protein	120
644917318	489	31.86	8	474	16	471	2.0e-66	246	COG1757	Na+/H+ antiporter NhaC	485
644917319	829	20.6	10	829	22	768	5.0e-32	133	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
644917320	159	34.64	1	153	3	154	2.0e-28	118	COG1522	DNA-binding transcriptional regulator, Lrp family	154
644917322	454	40.05	12	450	9	441	1.0e-130	460	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
644917323	393	24.32	14	388	10	408	8.0e-42	164	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
644917324	338	43.62	1	335	1	336	2.0e-95	342	COG3138	Arginine/ornithine N-succinyltransferase beta subunit	336
644917325	480	34.8	5	449	4	455	3.0e-98	352	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
644917326	446	55.91	9	446	5	441	0.0e+00	516	COG3724	Succinylarginine dihydrolase	442
644917332	145	43.48	54	145	3	93	2.0e-17	81.9	COG4891	Uncharacterized protein	93
644917333	262	38.98	18	252	1	234	5.0e-56	211	COG3208	Surfactin synthase thioesterase subunit	244
644917335	402	24.1	5	392	1	380	6.0e-49	188	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
644917337	76	27.78	1	72	4	75	2.0e-06	43.8	COG0236	Acyl carrier protein	80
644917338	638	33.39	51	632	10	572	6.0e-109	388	COG3882	Predicted enzyme involved in methoxymalonyl-ACP biosynthesis	574
644917339	338	26.32	1	318	1	303	3.0e-52	199	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
644917340	1025	44.82	35	932	1	902	0.0e+00	836	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
644917341	1868	39.52	35	1112	4	1043	0.0e+00	813	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
644917342	1629	45.17	41	935	4	871	0.0e+00	793	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
644917343	1896	43.96	33	1026	1	970	0.0e+00	901	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
644917344	1895	40.88	32	1110	1	1024	0.0e+00	864	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
644917345	1286	30.79	637	986	35	387	1.0e-58	222	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
644917345	1286	30.83	8	579	4	534	1.0e-86	315	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
644917352	535	36.75	4	531	2	486	4.0e-91	329	COG0286	Type I restriction-modification system, DNA methylase subunit	489
644917354	424	18.11	25	421	1	389	1.0e-20	94.7	COG0732	Restriction endonuclease S subunit	391
644917355	1021	27.92	4	959	8	906	1.0e-113	405	COG0610	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases ...	962
644917356	303	46.25	2	302	3	307	2.0e-82	299	COG1715	Restriction endonuclease Mrr	308
644917361	83	38.55	1	81	1	83	1.0e-08	51.6	COG3609	Transcriptional regulator, contains Arc/MetJ-type RHH (ribbon-helix-helix) DNA-binding domain	89
644917362	104	40.45	11	99	8	96	2.0e-13	67	COG3668	Plasmid stabilization system protein ParE	98
644917364	197	35.45	1	187	1	182	3.0e-38	152	COG2184	Fido, protein-threonine AMPylation domain	201
644917367	185	42.16	1	185	11	192	2.0e-27	115	COG0558	Phosphatidylglycerophosphate synthase	192
644917368	619	48.59	15	616	1	581	0.0e+00	626	COG0322	Excinuclease UvrABC, nuclease subunit	581
644917369	217	38.57	3	212	2	210	9.0e-49	186	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
644917370	207	31	4	200	3	194	1.0e-28	119	COG3145	Alkylated DNA repair dioxygenase AlkB	194
644917375	257	39.13	5	242	9	256	1.0e-54	206	COG0631	Serine/threonine protein phosphatase PrpC	262
644917377	345	23.78	3	287	2	278	8.0e-20	91.4	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
644917378	537	31.22	23	409	18	407	5.0e-32	132	COG1807	4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferase of PMT family	535
644917379	799	18.46	304	749	20	457	2.0e-19	91.3	COG1807	4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferase of PMT family	535
644917381	268	37.65	2	251	1	247	1.0e-62	233	COG1120	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	258
644917382	344	42.3	12	340	4	331	8.0e-50	191	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
644917383	200	48.48	3	200	1	198	3.0e-60	224	COG2109	ATP:corrinoid adenosyltransferase	198
644917385	671	67.42	8	669	3	657	0.0e+00	1086	COG0556	Excinuclease UvrABC helicase subunit UvrB	663
644917386	736	43.37	1	391	1	377	2.0e-109	390	COG0116	23S rRNA G2445 N2-methylase RlmL	381
644917387	68	51.85	1	54	1	54	8.0e-13	65.4	COG3130	Ribosome modulation factor	55
644917388	339	44.19	45	338	3	291	2.0e-80	292	COG0167	Dihydroorotate dehydrogenase	310
644917390	1607	44.57	37	1600	34	1589	0.0e+00	1528	COG2902	NAD-specific glutamate dehydrogenase	1592
644917391	321	41.28	1	320	9	327	1.0e-69	256	COG0714	MoxR-like ATPase	329
644917397	64	56.25	1	64	1	64	5.0e-17	79.6	COG1551	sRNA-binding carbon storage regulator CsrA	73
644917399	197	41.24	5	197	1	191	1.0e-43	169	COG2353	Polyisoprenoid-binding periplasmic protein YceI	192
644917400	177	40.68	1	177	3	179	9.0e-39	153	COG3038	Cytochrome b561	181
644917401	889	36.43	1	884	4	859	0.0e+00	630	COG0308	Aminopeptidase N	859
644917402	86	34.85	1	65	1	66	4.0e-13	66.6	COG3139	Uncharacterized conserved protein YeaC, DUF1315 family	90
644917403	289	29.15	82	274	10	207	3.0e-18	85.9	COG0705	Membrane associated serine protease, rhomboid family	228
644917405	293	44.37	7	289	3	281	2.0e-71	262	COG0061	NAD kinase	281
644917406	301	23.43	16	244	20	248	4.0e-20	92.4	COG3782	Uncharacterized protein	289
644917407	387	45.68	287	363	18	98	1.0e-10	61.5	COG0607	Rhodanese-related sulfurtransferase	110
644917408	309	28.52	12	303	16	315	1.0e-24	107	COG2515	1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase, PLP-dependent ACC family	323
644917413	896	46.5	3	596	1	557	0.0e+00	639	COG0550	DNA topoisomerase IA	570
644917417	142	28	1	141	2	151	1.0e-12	65.8	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
644917418	641	42.13	1	524	1	528	0.0e+00	522	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
644917419	666	31.85	363	653	1	290	3.0e-31	130	COG0741	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)	296
644917421	406	34.75	7	400	4	402	2.0e-70	259	COG3434	c-di-GMP-related signal transduction protein, contains EAL and HDOD domains	407
644917422	340	33.43	1	340	1	288	4.0e-66	245	COG0812	UDP-N-acetylenolpyruvoylglucosamine reductase	291
644917423	159	41.56	2	155	1	139	1.0e-36	146	COG0394	Protein-tyrosine-phosphatase	139
644917424	258	56.75	1	252	2	239	2.0e-87	315	COG1212	CMP-2-keto-3-deoxyoctulosonic acid synthetase	247
644917425	342	42.68	11	323	4	314	2.0e-78	286	COG1663	Tetraacyldisaccharide-1-P 4'-kinase	336
644917426	146	30.37	4	138	7	137	1.0e-21	96.1	COG0848	Biopolymer transport protein ExbD	137
644917427	208	32.02	1	202	12	214	8.0e-34	137	COG0811	Biopolymer transport protein ExbB/TolQ	216
644917428	785	35.21	523	783	37	293	9.0e-53	202	COG2333	Metal-dependent hydrolase, beta-lactamase superfamily II	293
644917429	177	30.9	1	175	4	180	4.0e-33	134	COG3216	Uncharacterized conserved protein, DUF2062 family	184
644917430	285	44.62	10	253	2	248	1.0e-65	243	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
644917431	438	47.54	1	182	2	180	2.0e-45	177	COG1386	Chromosome segregation and condensation protein ScpB	184
644917432	292	42.32	57	292	1	241	4.0e-46	178	COG1354	Chromatin segregation and condensation protein Rec8/ScpA/Scc1, kleisin family	248
644917433	224	42.72	20	224	1	205	2.0e-59	222	COG0009	tRNA A37 threonylcarbamoyladenosine synthetase subunit TsaC/SUA5/YrdC	211
644917434	275	42.8	4	252	4	250	5.0e-48	184	COG0613	Predicted metal-dependent phosphoesterase TrpH, contains PHP domain	258
644917436	99	48.98	1	98	1	92	2.0e-21	93.8	COG2350	Uncharacterized conserved protein YciI, contains a putative active-site phosphohistidine	92
644917437	213	21.43	1	209	12	200	5.0e-13	68	COG3103	Uncharacterized conserved protein YgiM, contains N-terminal SH3 domain, DUF1202 family	205
644917438	200	47.53	34	193	2	158	1.0e-43	169	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
644917439	255	40.32	4	255	1	240	7.0e-66	243	COG0854	Pyridoxine 5'-phosphate synthase PdxJ	243
644917440	258	32.51	17	258	21	256	5.0e-37	148	COG0566	tRNA G18 (ribose-2'-O)-methylase SpoU	260
644917442	428	56.45	22	428	1	404	9.0e-117	413	COG0004	Ammonia channel protein AmtB	409
644917444	325	22.64	43	321	4	298	7.0e-22	98.3	COG1721	Uncharacterized conserved protein, DUF58 family, contains vWF domain	416
644917445	274	42.96	1	273	47	328	9.0e-57	213	COG0714	MoxR-like ATPase	329
644917447	402	47.68	17	400	8	393	4.0e-125	441	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
644917448	506	52.87	1	483	4	470	0.0e+00	600	COG0034	Glutamine phosphoribosylpyrophosphate amidotransferase	470
644917449	165	37.84	1	148	1	148	9.0e-25	106	COG1286	Uncharacterized membrane protein, required for colicin V production	182
644917451	336	27.89	41	291	8	251	2.0e-08	53.5	COG0730	Uncharacterized membrane protein YfcA	258
644917452	174	20.8	1	173	1	226	3.0e-11	61.6	COG3147	Cell division protein DedD (periplasmic protein involved in septation)	226
644917453	436	38.48	1	436	1	422	5.0e-86	311	COG0285	Folylpolyglutamate synthase/Dihydropteroate synthase	427
644917454	289	57.99	1	288	1	286	9.0e-110	390	COG0777	Acetyl-CoA carboxylase beta subunit	294
644917455	271	43.28	1	268	1	265	1.0e-76	280	COG0159	Tryptophan synthase alpha chain	265
644917456	404	69.8	10	403	1	393	0.0e+00	694	COG0133	Tryptophan synthase beta chain	396
644917457	208	42.31	1	203	2	207	1.0e-56	212	COG0135	Phosphoribosylanthranilate isomerase	208
644917458	286	48.02	22	273	1	251	1.0e-85	309	COG0101	tRNA U38,U39,U40 pseudouridine synthase TruA	266
644917459	1158	24.44	4	782	15	730	7.0e-38	153	COG3170	Tfp pilus assembly protein FimV	755
644917460	368	30.05	1	365	2	333	1.0e-89	323	COG0136	Aspartate-semialdehyde dehydrogenase	334
644917461	357	55.25	1	357	2	345	5.0e-126	444	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
644917462	215	51.18	1	210	1	190	6.0e-73	267	COG0066	3-isopropylmalate dehydratase small subunit	191
644917463	474	52.74	2	472	1	422	0.0e+00	583	COG0065	Homoaconitase/3-isopropylmalate dehydratase large subunit	423
644917464	295	33.67	1	294	1	296	1.0e-39	157	COG0583	DNA-binding transcriptional regulator, LysR family	297
644917468	362	58.13	2	357	1	362	0.0e+00	533	COG0082	Chorismate synthase	369
644917469	305	35.27	11	300	2	280	6.0e-53	201	COG2890	Methylase of polypeptide chain release factors	280
644917470	184	51.06	1	184	7	194	5.0e-69	253	COG0302	GTP cyclohydrolase I	195
644917473	299	20.29	10	277	4	272	1.0e-12	67.4	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
644917474	153	33.33	1	153	2	157	1.0e-21	96.1	COG2062	Phosphohistidine phosphatase SixA	163
644917476	340	49.84	6	326	3	323	6.0e-107	381	COG0240	Glycerol-3-phosphate dehydrogenase	329
644917477	632	58.95	4	628	1	618	0.0e+00	816	COG0326	Molecular chaperone, HSP90 family	623
644917479	290	72.51	1	290	1	291	3.0e-124	438	COG0074	Succinyl-CoA synthetase, alpha subunit	293
644917480	389	64.01	1	387	1	386	0.0e+00	533	COG0045	Succinyl-CoA synthetase, beta subunit	387
644917481	483	45.94	1	467	1	454	0.0e+00	478	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
644917482	412	51.8	1	411	1	404	4.0e-115	408	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
644917483	945	56.03	6	941	1	904	0.0e+00	1284	COG0567	2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes	906
644917484	234	54.7	1	233	2	231	2.0e-80	292	COG0479	Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit	234
644917485	590	50.95	4	575	2	561	0.0e+00	624	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
644917486	123	33.33	1	117	2	117	7.0e-13	66	COG2142	Succinate dehydrogenase, hydrophobic anchor subunit	117
644917487	124	37.6	5	124	3	127	8.0e-16	76.1	COG2009	Succinate dehydrogenase/fumarate reductase, cytochrome b subunit	132
644917488	437	52.11	28	429	1	390	0.0e+00	487	COG0372	Citrate synthase	390
644917489	315	32.89	1	301	4	290	3.0e-66	245	COG1131	ABC-type multidrug transport system, ATPase component	293
644917490	978	19	13	197	5	204	5.0e-14	74	COG1277	ABC-type transport system involved in multi-copper enzyme maturation, permease component	278
644917492	604	37.55	12	527	31	513	2.0e-117	416	COG0513	Superfamily II DNA and RNA helicase	513
644917493	448	26.49	29	444	13	416	4.0e-44	172	COG1721	Uncharacterized conserved protein, DUF58 family, contains vWF domain	416
644917494	327	45.14	15	326	12	329	1.0e-66	246	COG0714	MoxR-like ATPase	329
644917497	314	34.6	87	296	3	207	5.0e-28	118	COG1300	Uncharacterized membrane protein SpoIIM, required for sporulation	207
644917498	232	33.33	14	159	7	156	8.0e-12	64.4	COG1714	Uncharacterized membrane protein YckC, RDD family	172
644917501	208	47.32	2	206	1	204	3.0e-55	207	COG0545	FKBP-type peptidyl-prolyl cis-trans isomerase	205
644917502	309	47.32	1	297	1	298	4.0e-90	324	COG2974	DNA recombination-dependent growth factor C	303
644917503	208	36.52	29	204	1	178	3.0e-39	155	COG4681	Uncharacterized conserved protein YaeQ, suppresses RfaH defect	181
644917504	629	34.04	301	624	31	339	5.0e-62	232	COG3693	Endo-1,4-beta-xylanase, GH35 family	345
644917508	226	55.07	1	225	3	228	5.0e-74	270	COG3128	Predicted 2-oxoglutarate- and Fe(II)-dependent dioxygenase YbiX	229
644917509	371	35.31	15	362	1	349	9.0e-67	247	COG1304	FMN-dependent dehydrogenase, includes L-lactate dehydrogenase and type II isopentenyl diphosphate isomerase	360
644917510	796	28.79	22	796	21	750	8.0e-101	361	COG4774	Outer membrane receptor for monomeric catechols	750
644917511	290	19.86	1	287	2	243	6.0e-14	71.7	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
644917512	139	30.77	10	131	2	130	3.0e-14	71	COG0848	Biopolymer transport protein ExbD	137
644917513	138	26.05	14	129	16	130	4.0e-07	47.5	COG0848	Biopolymer transport protein ExbD	137
644917514	217	26.57	1	207	9	212	7.0e-23	100	COG0811	Biopolymer transport protein ExbB/TolQ	216
644917515	354	42.31	15	347	5	340	2.0e-81	296	COG0430	RNA 3'-terminal phosphate cyclase	341
644917516	409	35.99	9	409	1	432	8.0e-109	387	COG1690	RNA-splicing ligase RtcB, repairs tRNA damage	432
644917517	532	55.53	2	532	3	526	0.0e+00	639	COG4650	Sigma54-dependent transcription regulator containing an AAA-type ATPase domain and a DNA-binding domain	531
644917519	392	35.74	63	359	3	296	1.0e-66	247	COG1162	Putative ribosome biogenesis GTPase RsgA	301
644917528	500	39.42	2	473	9	471	2.0e-119	423	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
644917530	192	27.09	1	187	1	202	6.0e-17	80.8	COG0778	Nitroreductase	207
644917531	227	39.3	1	201	4	196	1.0e-30	126	COG2095	Small neutral amino acid transporter SnatA, MarC family	203
644917533	155	49.35	1	154	1	154	7.0e-48	183	COG0783	DNA-binding ferritin-like protein (oxidative damage protectant)	156
644917534	338	34.21	13	310	12	303	2.0e-72	266	COG0042	tRNA-dihydrouridine synthase	323
644917535	310	37.79	5	307	1	238	1.0e-63	236	COG0176	Transaldolase	239
644917536	148	31.94	1	144	3	146	4.0e-19	87.3	COG4103	Uncharacterized conserved protein, tellurite resistance protein B (TerB) family	148
644917537	563	25.37	96	556	71	530	6.0e-49	189	COG1315	Uncharacterized conserved protein, DUF342 family	543
644917539	324	26.34	70	321	19	277	6.0e-23	101	COG1639	HD-like signal output (HDOD) domain, no enzymatic activity	289
644917540	326	36.5	1	317	1	311	7.0e-58	217	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
644917542	1299	39.57	169	989	3	741	0.0e+00	743	COG0046	Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain	743
644917543	492	40.97	30	482	16	462	8.0e-122	430	COG4623	Membrane-bound lytic murein transglycosylase MltF	473
644917544	164	49.32	1	147	4	151	2.0e-43	168	COG0590	tRNA(Arg) A34 adenosine deaminase TadA	152
644917546	106	36.26	12	102	29	115	2.0e-20	90.9	COG4728	Uncharacterized protein	124
644917548	732	21.4	306	724	1	387	1.0e-21	98.8	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
644917548	732	35.11	12	271	13	252	1.0e-63	238	COG4121	tRNA U34 5-methylaminomethyl-2-thiouridine-forming methyltransferase MnmC	252
644917551	262	40.38	1	256	1	260	4.0e-59	221	COG3823	Glutamine cyclotransferase	262
644917552	438	44.21	4	381	8	347	7.0e-104	371	COG0826	Collagenase-like protease, PrtC family	347
644917553	283	34.28	3	280	14	285	2.0e-52	199	COG0676	D-hexose-6-phosphate mutarotase	287
644917556	246	31.13	23	233	2	212	4.0e-34	138	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
644917558	123	32.5	4	121	3	122	7.0e-12	63	COG3094	Uncharacterized membrane protein SirB2	129
644917561	525	68.65	207	525	1	315	0.0e+00	548	COG0519	GMP synthase, PP-ATPase domain/subunit	315
644917562	491	28.83	256	477	1	169	3.0e-32	133	COG0516	IMP dehydrogenase/GMP reductase	170
644917563	453	48.18	9	446	1	435	0.0e+00	477	COG1570	Exonuclease VII, large subunit	440
644917565	267	28.92	6	263	5	291	5.0e-36	144	COG0384	Predicted epimerase YddE/YHI9, PhzF superfamily	291
644917567	387	23.29	19	361	5	363	2.0e-23	103	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
644917568	71	40.3	6	71	2	68	1.0e-12	64.5	COG2104	Sulfur carrier protein ThiS (thiamine biosynthesis)	68
644917569	268	54.75	4	266	1	262	3.0e-102	364	COG2022	Thiamin biosynthesis thiazole synthase ThiGH, ThiG subunit	262
644917570	268	36.48	4	232	26	255	5.0e-48	184	COG1119	ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA	257
644917571	278	28.52	9	271	8	255	2.0e-08	53.5	COG0730	Uncharacterized membrane protein YfcA	258
644917574	464	48.76	1	440	2	444	0.0e+00	542	COG1160	Predicted GTPases	444
644917575	421	24.42	1	369	3	360	4.0e-33	136	COG1520	Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat	370
644917576	234	34.56	1	217	1	206	1.0e-31	130	COG2976	Putative negative regulator of RcsB-dependent stress response	207
644917577	423	47.2	1	418	1	420	0.0e+00	467	COG0124	Histidyl-tRNA synthetase	429
644917578	313	23.16	18	281	3	284	4.0e-23	102	COG1426	Cytoskeletal protein RodZ, contains Xre-like HTH and DUF4115 domains	284
644917579	270	32.93	19	266	2	248	7.0e-39	154	COG3063	Tfp pilus assembly protein PilF	250
644917580	399	51.12	19	374	1	349	2.0e-122	432	COG0820	Adenine C2-methylase RlmN of 23S rRNA A2503 and tRNA A37	349
644917581	141	66.67	2	136	1	135	7.0e-55	206	COG0105	Nucleoside diphosphate kinase	135
644917582	731	19.03	7	518	3	504	2.0e-14	75	COG2982	Uncharacterized protein involved in outer membrane biogenesis	648
644917583	182	43.56	26	181	2	160	1.0e-43	169	COG0386	Glutathione peroxidase, house-cleaning role in reducing lipid peroxides	162
644917584	142	47.48	5	142	2	140	8.0e-43	165	COG2166	Sulfur transfer protein SufE, Fe-S center assembly	144
644917585	154	39.05	49	153	7	111	1.0e-26	112	COG2151	Metal-sulfur cluster biosynthetic enzyme	111
644917586	116	37.96	11	116	4	110	2.0e-22	98	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
644917587	417	55.17	14	416	2	405	2.0e-130	459	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
644917588	440	27.18	34	412	32	394	2.0e-62	233	COG0719	Fe-S cluster assembly scaffold protein SufB	412
644917589	256	59.45	3	255	1	250	3.0e-97	348	COG0396	Fe-S cluster assembly ATPase SufC	251
644917590	479	41.96	35	477	1	412	1.0e-121	430	COG0719	Fe-S cluster assembly scaffold protein SufB	412
644917591	391	51.92	3	388	1	386	0.0e+00	483	COG1104	Cysteine sulfinate desulfinase/cysteine desulfurase or related enzyme	386
644917592	164	41.35	1	132	1	133	6.0e-36	143	COG1959	DNA-binding transcriptional regulator, IscR family	150
644917593	261	45.31	6	250	2	241	3.0e-81	294	COG0565	tRNA C32,U32 (ribose-2'-O)-methylase TrmJ or a related methyltransferase	242
644917594	267	49.23	1	258	1	258	2.0e-71	262	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
644917595	691	34.92	288	538	95	336	1.0e-40	161	COG0642	Signal transduction histidine kinase	336
644917597	308	45.85	4	302	7	305	3.0e-77	282	COG0341	Preprotein translocase subunit SecF	305
644917598	621	46.68	100	621	16	506	4.0e-128	452	COG0342	Preprotein translocase subunit SecD	506
644917599	380	63.14	8	375	1	369	0.0e+00	550	COG0343	Queuine/archaeosine tRNA-ribosyltransferase	372
644917600	359	58.91	1	344	1	348	0.0e+00	503	COG0809	S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase)	348
644917609	285	30.96	1	274	4	261	2.0e-44	173	COG0300	Short-chain dehydrogenase	265
644917610	191	23.44	1	191	5	196	2.0e-11	62.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
644917611	259	48.02	6	255	5	255	1.0e-85	309	COG0024	Methionine aminopeptidase	255
644917621	218	40.25	4	215	12	236	3.0e-57	214	COG4312	Predicted dithiol-disulfide oxidoreductase, DUF899 family	247
644917622	340	23.74	7	340	3	324	7.0e-55	207	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
644917623	97	24.72	1	89	2	90	5.0e-07	46.1	COG1359	Quinol monooxygenase YgiN	100
644917642	703	19.75	8	651	1	659	2.0e-13	71.5	COG4771	Outer membrane receptor for ferrienterochelin and colicins	699
644917643	388	32.39	61	344	65	344	5.0e-54	205	COG2206	HD-GYP domain, c-di-GMP phosphodiesterase class II (or its inactivated variant)	344
644917644	548	29.57	251	548	1	294	7.0e-43	168	COG1597	Diacylglycerol kinase family enzyme	301
644917647	335	65.37	3	335	1	334	0.0e+00	481	COG0057	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase	335
644917648	496	49.79	1	483	6	480	0.0e+00	584	COG0364	Glucose-6-phosphate 1-dehydrogenase	483
644917652	354	25.14	1	354	1	362	8.0e-44	171	COG0795	Lipopolysaccharide export LptBFGC system, permease protein LptF	364
644917653	378	29.97	1	367	2	364	6.0e-43	168	COG0795	Lipopolysaccharide export LptBFGC system, permease protein LptF	364
644917654	509	46.85	6	508	4	482	0.0e+00	492	COG0260	Leucyl aminopeptidase	485
644917655	140	33.79	1	140	1	142	1.0e-26	111	COG2927	DNA polymerase III, chi subunit	144
644917656	1134	34.34	892	1089	1	179	7.0e-38	153	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
644917658	922	54.92	1	921	1	877	0.0e+00	1225	COG0525	Valyl-tRNA synthetase	877
644917659	253	49.79	4	243	8	246	2.0e-79	289	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
644917660	140	27.14	2	140	1	140	3.0e-26	110	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
644917661	462	28.76	1	452	11	522	8.0e-54	204	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
644917662	323	29.56	9	311	5	305	1.0e-28	120	COG1441	O-succinylbenzoate synthase	321
644917663	282	71.01	12	282	7	282	3.0e-127	447	COG0447	1,4-Dihydroxy-2-naphthoyl-CoA synthase	282
644917664	250	19.39	6	247	21	279	1.0e-06	47	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
644917665	564	35	3	562	2	564	4.0e-112	399	COG1165	2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase	566
644917666	462	34.31	20	457	1	419	2.0e-71	263	COG1169	Isochorismate synthase EntC	423
644917668	335	62.12	5	334	2	324	0.0e+00	468	COG0158	Fructose-1,6-bisphosphatase	326
644917669	864	22.19	539	843	59	375	9.0e-07	49.6	COG4222	Uncharacterized conserved protein	391
644917670	313	30.97	14	313	4	296	1.0e-39	157	COG0501	Zn-dependent protease with chaperone function	302
644917673	72	38.24	5	72	10	72	8.0e-08	48.8	COG2900	Uncharacterized coiled-coil protein SlyX (sensitive to lysis X)	72
644917674	151	55.86	2	145	9	151	1.0e-43	169	COG2983	Uncharacterized cysteine cluster protein YcgN, CxxCxxCC family	153
644917675	95	39.78	3	95	10	99	8.0e-18	81.9	COG3100	Uncharacterized conserved protein YcgL, UPF0745 family	103
644917676	393	37.33	13	384	1	360	5.0e-74	271	COG0349	Ribonuclease D	361
644917677	197	55.33	1	197	2	198	1.0e-77	282	COG0353	Recombinational DNA repair protein RecR	198
644917678	106	62.5	1	103	4	105	5.0e-22	96.1	COG0718	Conserved DNA-binding protein YbaB (function unknown)	105
644917679	672	42.03	1	494	1	499	5.0e-130	458	COG2812	DNA polymerase III, gamma/tau subunits	515
644917680	538	26.85	148	538	21	407	3.0e-36	146	COG0840	Methyl-accepting chemotaxis protein	408
644917681	661	19.42	193	521	32	324	4.0e-06	47.1	COG0420	DNA repair exonuclease SbcCD nuclease subunit	390
644917687	393	37.12	22	311	36	317	9.0e-57	214	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
644917688	372	31.4	6	369	3	364	3.0e-99	355	COG1932	Phosphoserine aminotransferase	365
644917689	284	44.48	4	284	24	304	1.0e-72	266	COG3118	Negative regulator of GroEL, contains thioredoxin-like and TPR-like domains	304
644917690	241	39.44	1	238	4	250	1.0e-45	176	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
644917694	169	35.15	2	156	10	174	1.0e-28	119	COG5394	Polyhydroxyalkanoate (PHA) synthesis regulator protein, binds DNA and PHA	193
644917695	616	46.04	148	597	2	444	0.0e+00	467	COG3243	Poly(3-hydroxyalkanoate) synthetase	445
644917696	255	38.02	1	253	1	251	9.0e-41	160	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
644917698	812	34.71	1	809	271	1055	0.0e+00	742	COG3459	Cellobiose phosphorylase	1056
644917701	466	31.53	6	463	3	452	9.0e-83	301	COG2211	Na+/melibiose symporter or related transporter	467
644917702	797	31.99	1	776	271	1032	0.0e+00	538	COG3459	Cellobiose phosphorylase	1056
644917703	254	31.92	5	252	7	265	8.0e-39	154	COG0647	Ribonucleotide monophosphatase NagD, HAD superfamily	269
644917705	127	35.94	8	69	2	65	9.0e-12	62.5	COG1983	Phage shock protein PspC (stress-responsive transcriptional regulator)	70
644917707	223	38.29	1	218	1	222	7.0e-23	100	COG1842	Phage shock protein A	225
644917710	179	26.77	25	151	13	138	7.0e-15	73.8	COG1664	Cytoskeletal protein CcmA, bactofilin family	146
644917712	324	28.95	15	318	7	262	2.0e-38	153	COG1975	Xanthine and CO dehydrogenase maturation factor, XdhC/CoxF family	278
644917713	368	23.55	63	350	29	316	2.0e-07	50	COG3528	Uncharacterized protein	330
644917714	191	22.94	1	169	4	171	3.0e-12	65.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
644917715	204	34.34	7	203	4	200	9.0e-42	163	COG1739	Putative translation regulator, IMPACT (imprinted ancient) protein family	203
644917716	321	53.95	1	303	2	305	1.0e-118	419	COG1054	Predicted sulfurtransferase	308
644917717	102	47.67	4	88	5	90	8.0e-23	98.5	COG0271	Stress-induced morphogen (activity unknown)	90
644917720	482	48.64	1	477	3	477	0.0e+00	534	COG0469	Pyruvate kinase	477
644917721	436	65.13	1	433	1	375	0.0e+00	478	COG1883	Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit	375
644917722	595	62.11	5	478	3	468	0.0e+00	703	COG5016	Pyruvate/oxaloacetate carboxyltransferase	472
644917723	83	34.62	5	82	6	82	3.0e-09	53.4	COG3630	Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, gamma subunit	84
644917724	320	39.43	1	315	11	316	1.0e-67	250	COG0042	tRNA-dihydrouridine synthase	323
644917725	534	43.94	9	529	16	531	0.0e+00	493	COG0405	Gamma-glutamyltranspeptidase	539
644917726	152	57.04	8	149	1	142	4.0e-54	203	COG1803	Methylglyoxal synthase	142
644917734	650	29.52	190	517	7	334	1.0e-34	142	COG0642	Signal transduction histidine kinase	336
644917735	212	33.97	9	204	2	209	7.0e-36	143	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
644917740	64	59.38	1	64	1	64	2.0e-18	83.8	COG1551	sRNA-binding carbon storage regulator CsrA	73
644917741	406	43.83	1	405	1	447	8.0e-114	404	COG0527	Aspartokinase	447
644917742	866	56.69	1	865	5	879	0.0e+00	1146	COG0013	Alanyl-tRNA synthetase	879
644917743	117	43.1	3	115	1	113	4.0e-27	113	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
644917744	64	55	2	61	1	60	1.0e-15	74.9	COG2835	Uncharacterized conserved protein YbaR, Trm112 family	60
644917746	338	22.15	2	320	12	320	5.0e-27	115	COG0429	Predicted hydrolase of the alpha/beta-hydrolase fold	345
644917747	162	26.54	1	162	2	153	4.0e-07	47.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
644917748	430	59.29	5	397	5	394	0.0e+00	550	COG0133	Tryptophan synthase beta chain	396
644917749	254	37.66	16	254	24	262	6.0e-55	207	COG0159	Tryptophan synthase alpha chain	265
644917751	171	40.36	9	171	16	172	2.0e-22	98.8	COG2137	SOS response regulatory protein OraA/RecX, interacts with RecA	174
644917753	342	63.86	1	281	3	279	3.0e-85	308	COG0468	RecA/RadA recombinase	279
644917754	172	50.32	11	165	8	162	3.0e-43	168	COG1546	Nicotinamide mononucleotide (NMN) deamidase PncC	162
644917758	864	50.52	11	862	2	843	0.0e+00	942	COG0249	DNA mismatch repair ATPase MutS	843
644917759	107	42.42	4	65	5	68	4.0e-08	50.2	COG1146	NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit	68
644917760	337	46.85	52	334	57	342	6.0e-76	277	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
644917762	322	38.8	12	253	2	239	1.0e-38	154	COG2035	Uncharacterized membrane protein	276
644917763	214	48.8	5	212	1	205	3.0e-59	221	COG2518	Protein-L-isoaspartate O-methyltransferase	209
644917764	329	27.09	5	316	7	395	6.0e-55	208	COG0585	tRNA(Glu) U13 pseudouridine synthase TruD	406
644917765	157	37.66	1	153	1	154	3.0e-22	97.9	COG0245	2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	159
644917766	91	47.25	1	91	24	114	2.0e-19	87.3	COG2919	Cell division protein FtsB	117
644917767	465	42.34	1	462	3	458	1.0e-124	439	COG0415	Deoxyribodipyrimidine photolyase	461
644917770	206	35.09	38	202	22	192	1.0e-31	129	COG2353	Polyisoprenoid-binding periplasmic protein YceI	192
644917771	888	32.3	76	425	50	367	3.0e-56	214	COG1472	Periplasmic beta-glucosidase and related glycosidases	397
644917772	726	51.54	29	703	4	678	0.0e+00	814	COG3661	Alpha-glucuronidase	684
644917773	695	60.71	6	695	7	700	0.0e+00	784	COG3808	Na+ or H+-translocating membrane pyrophosphatase	703
644917774	242	29.67	2	231	1	244	1.0e-30	126	COG0300	Short-chain dehydrogenase	265
644917775	717	53.07	390	710	1	325	4.0e-109	389	COG0280	Phosphotransacetylase	327
644917776	401	50.25	4	394	3	393	0.0e+00	490	COG0282	Acetate kinase	396
644917778	439	66.12	11	438	1	421	0.0e+00	625	COG0148	Enolase	423
644917779	283	64.77	2	282	1	279	2.0e-127	448	COG2877	3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase	279
644917780	540	63.22	2	540	1	531	0.0e+00	865	COG0504	CTP synthase (UTP-ammonia lyase)	533
644917781	436	35.27	22	237	26	248	3.0e-40	160	COG0037	tRNA(Ile)-lysidine synthase TilS/MesJ	298
644917782	650	25.26	166	646	154	615	2.0e-62	234	COG1506	Dipeptidyl aminopeptidase/acylaminoacyl peptidase	620
644917783	122	21.57	14	113	21	122	5.0e-10	56.6	COG0662	Mannose-6-phosphate isomerase, cupin superfamily	127
644917784	253	38.89	11	243	2	233	2.0e-56	212	COG3208	Surfactin synthase thioesterase subunit	244
644917785	1059	23.16	4	1039	2	1009	2.0e-130	461	COG0841	Multidrug efflux pump subunit AcrB	1009
644917786	397	22.83	6	377	4	366	1.0e-13	70.9	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
644917787	7446	38.6	1050	1731	1	641	0.0e+00	483	COG1020	Non-ribosomal peptide synthetase component F	642
644917788	1812	36.63	960	1629	1	642	4.0e-118	420	COG1020	Non-ribosomal peptide synthetase component F	642
644917789	4434	36.63	3582	4251	1	642	1.0e-122	436	COG1020	Non-ribosomal peptide synthetase component F	642
644917790	573	33.74	70	561	54	540	5.0e-101	361	COG4615	ABC-type siderophore export system, fused ATPase and permease components	546
644917791	824	28.11	11	803	5	753	2.0e-113	403	COG2366	Acyl-homoserine lactone (AHL) acylase PvdQ	768
644917795	279	19.79	8	273	6	282	3.0e-11	62.8	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
644917797	172	44.37	22	171	1	150	1.0e-34	138	COG0782	Transcription elongation factor, GreA/GreB family	151
644917799	391	48.72	1	387	1	392	0.0e+00	484	COG1448	Aspartate/tyrosine/aromatic aminotransferase	396
644917800	155	40	1	155	1	154	4.0e-29	120	COG1522	DNA-binding transcriptional regulator, Lrp family	154
644917801	119	56.78	1	118	1	118	1.0e-30	124	COG0818	Diacylglycerol kinase	123
644917802	211	53.81	3	211	5	214	5.0e-78	284	COG0259	Pyridoxine/pyridoxamine 5'-phosphate oxidase	214
644917803	217	33.5	3	208	1	188	2.0e-31	129	COG0746	Molybdopterin-guanine dinucleotide biosynthesis protein A	192
644917810	1066	13.3	465	1065	194	767	5.0e-07	50.7	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
644917812	202	26.47	17	186	14	179	3.0e-15	75.1	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
644917820	1010	42.86	595	1010	19	444	3.0e-80	293	COG5297	Cellulase/cellobiase CelA1	544
644917822	650	42.73	236	650	19	443	3.0e-79	290	COG5297	Cellulase/cellobiase CelA1	544
644917825	685	17.43	35	685	51	768	6.0e-22	99.6	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
644917826	1077	29.32	24	1065	12	1005	0.0e+00	622	COG0841	Multidrug efflux pump subunit AcrB	1009
644917827	348	29.48	10	330	27	354	4.0e-16	79.4	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
644917829	127	32.67	20	120	11	110	2.0e-10	57.9	COG0640	DNA-binding transcriptional regulator, ArsR family	110
644917832	299	35.71	7	280	33	308	1.0e-55	210	COG1477	Thiamine biosynthesis lipoprotein ApbE	337
644917835	173	22.01	24	168	1	155	2.0e-11	62.2	COG1225	Peroxiredoxin	157
644917841	575	29.01	8	250	6	260	3.0e-35	143	COG0631	Serine/threonine protein phosphatase PrpC	262
644917843	363	18.77	1	294	2	355	8.0e-15	75.1	COG1819	UDP:flavonoid glycosyltransferase YjiC, YdhE family	406
644917845	224	27.98	2	218	3	217	4.0e-19	88.5	COG2761	Predicted dithiol-disulfide isomerase, DsbA family	225
644917846	296	29.26	7	289	10	305	1.0e-32	133	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
644917851	1033	35.81	1	1033	2	1070	0.0e+00	937	COG0587	DNA polymerase III, alpha subunit	1139
644917853	319	48.43	1	318	5	319	5.0e-97	347	COG0837	Glucokinase	320
644917854	263	34.31	30	166	1	131	7.0e-27	114	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
644917855	340	30.09	14	340	3	340	2.0e-58	219	COG0673	Predicted dehydrogenase	342
644917856	1143	39.02	840	1142	80	407	1.0e-51	199	COG0840	Methyl-accepting chemotaxis protein	408
644917857	102	38.2	11	98	11	99	1.0e-09	54.8	COG0640	DNA-binding transcriptional regulator, ArsR family	110
644917858	178	29.79	21	113	19	110	6.0e-08	50.7	COG0607	Rhodanese-related sulfurtransferase	110
644917859	222	41.05	1	221	1	228	4.0e-50	191	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
644917860	427	24.2	147	415	40	314	2.0e-19	90.6	COG0642	Signal transduction histidine kinase	336
644917862	288	26.32	1	286	1	296	2.0e-39	156	COG3221	ABC-type phosphate/phosphonate transport system, periplasmic component	299
644917863	223	33.07	3	223	1	249	3.0e-40	158	COG3638	ABC-type phosphate/phosphonate transport system, ATPase component	258
644917867	111	33.64	7	111	4	106	4.0e-17	79.6	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
644917868	848	48.89	1	809	1	793	0.0e+00	977	COG1251	NAD(P)H-nitrite reductase, large subunit	793
644917869	265	52.7	11	251	1	240	8.0e-81	293	COG0007	Uroporphyrinogen-III methylase (siroheme synthase)	244
644917870	93	60.87	2	93	8	99	6.0e-32	129	COG3492	Uncharacterized protein	104
644917871	284	32.73	5	279	4	257	4.0e-38	152	COG3217	Uncharacterized conserved protein YcbX, contains MOSC and Fe-S domains	270
644917873	1024	29	28	552	8	458	2.0e-68	254	COG0277	FAD/FMN-containing dehydrogenase	459
644917874	895	23.69	39	794	1	759	2.0e-77	284	COG0308	Aminopeptidase N	859
644917875	288	54.55	1	286	1	286	9.0e-115	406	COG0788	Formyltetrahydrofolate hydrolase	287
644917876	273	36.36	5	250	1	251	9.0e-38	150	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
644917877	259	38.62	11	252	12	255	2.0e-48	185	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
644917878	578	40.68	1	578	1	577	0.0e+00	568	COG0018	Arginyl-tRNA synthetase	577
644917880	704	30.64	10	699	1	634	9.0e-113	401	COG1199	Rad3-related DNA helicase	654
644917884	341	38.68	1	316	3	311	6.0e-83	301	COG0540	Aspartate carbamoyltransferase, catalytic chain	316
644917885	478	50.85	3	469	10	473	0.0e+00	581	COG2925	Exonuclease I	475
644917886	211	42.23	1	203	1	206	9.0e-57	213	COG0288	Carbonic anhydrase	207
644917887	189	40.62	3	189	2	181	4.0e-59	220	COG0717	Deoxycytidine triphosphate deaminase	183
644917888	364	47.96	97	314	55	264	4.0e-56	212	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
644917889	678	40.11	6	551	1	558	0.0e+00	626	COG0143	Methionyl-tRNA synthetase	558
644917890	191	73.3	1	191	1	191	5.0e-65	240	COG4657	Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfA subunit	193
644917891	200	56.61	10	197	4	192	1.0e-59	222	COG2878	Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit	198
644917892	747	48.92	6	515	3	509	0.0e+00	525	COG4656	Na+-translocating ferredoxin:NAD+ oxidoreductase  RNF, RnfC subunit	529
644917893	349	50.44	2	343	1	337	5.0e-90	324	COG4658	Na+-translocating ferredoxin:NAD+ oxidoreductase  RNF, RnfD subunit	338
644917894	214	47.47	4	201	2	195	7.0e-53	200	COG4659	Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfG subunit	195
644917895	236	58.22	1	213	1	212	5.0e-72	264	COG4660	Na+-translocating ferredoxin:NAD+ oxidoreductase  RNF, RnfE subunit	212
644917896	220	20.92	1	191	2	240	5.0e-13	68.3	COG1192	Cellulose biosynthesis protein BcsQ	259
644917897	697	34.59	222	692	2	455	6.0e-108	385	COG0147	Anthranilate/para-aminobenzoate synthases component I	462
644917898	127	25.53	1	125	1	138	6.0e-13	66.4	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
644917901	113	48.11	9	112	3	108	2.0e-26	110	COG0393	Uncharacterized conserved protein YbjQ, UPF0145 family	108
644917903	163	35.76	14	162	31	181	8.0e-22	96.7	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
644917905	184	31.55	1	174	2	188	3.0e-20	91.8	COG0693	Putative intracellular protease/amidase	188
644917906	240	40	4	224	5	226	7.0e-34	137	COG2836	Sulfite exporter TauE/SafE	232
644917907	81	46.3	1	54	1	54	3.0e-12	63.7	COG3197	Uncharacterized protein, possibly involved in nitrogen fixation	58
644917908	796	38.97	88	795	5	706	0.0e+00	577	COG2217	Cation transport ATPase	713
644917909	164	27.27	1	163	1	159	2.0e-20	92.1	COG3198	Uncharacterized protein	172
644917910	477	35.7	28	406	2	353	2.0e-68	253	COG0348	Polyferredoxin	386
644917911	291	26.67	75	216	3	149	6.0e-13	68.1	COG2010	Cytochrome c, mono- and diheme variants	150
644917912	66	26.79	1	54	5	60	6.0e-06	42.5	COG4736	Cbb3-type cytochrome oxidase, subunit 3	60
644917913	203	60.99	2	203	1	223	2.0e-89	321	COG2993	Cbb3-type cytochrome oxidase, cytochrome c subunit	227
644917914	480	73.53	7	480	6	481	0.0e+00	693	COG3278	Cbb3-type cytochrome oxidase, subunit 1	482
644917915	411	59.61	7	410	3	403	0.0e+00	600	COG0137	Argininosuccinate synthase	403
644917916	232	35.5	4	217	6	233	4.0e-32	131	COG0390	ABC-type iron transport system FetAB, permease component	256
644917919	344	64.83	1	343	1	344	0.0e+00	518	COG0418	Dihydroorotase	344
644917920	211	30.4	10	210	2	228	6.0e-20	91	COG0847	DNA polymerase III, epsilon subunit or related 3'-5' exonuclease	243
644917921	409	45.06	1	406	1	410	5.0e-124	437	COG3977	Alanine-alpha-ketoisovalerate (or valine-pyruvate) aminotransferase	417
644917923	428	29.24	13	279	10	286	3.0e-32	133	COG1295	Uncharacterized membrane protein, BrkB/YihY/UPF0761 family (not an RNase)	303
644917924	117	42.61	3	117	1	115	3.0e-28	117	COG1393	Arsenate reductase and related proteins, glutaredoxin family	117
644917925	196	33.82	1	196	3	207	2.0e-33	135	COG0655	Multimeric flavodoxin WrbA	207
644917926	130	25.81	3	125	2	125	4.0e-08	50.3	COG3308	Uncharacterized membrane protein	131
644917927	618	35.67	266	579	6	317	4.0e-59	223	COG0616	Periplasmic serine protease, ClpP class	317
644917929	376	25.85	33	355	32	330	2.0e-24	107	COG3249	Uncharacterized protein	343
644917930	352	65.12	9	349	1	344	0.0e+00	508	COG0150	Phosphoribosylaminoimidazole (AIR) synthetase	345
644917931	216	57.79	10	208	2	200	5.0e-80	290	COG0299	Folate-dependent phosphoribosylglycinamide formyltransferase PurN	200
644917933	123	36.54	20	123	1	101	1.0e-21	95.4	COG2154	Pterin-4a-carbinolamine dehydratase	101
644917934	506	46.73	1	303	1	297	3.0e-104	372	COG1951	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain	297
644917936	193	54.27	1	193	2	199	5.0e-72	263	COG0605	Superoxide dismutase	204
644917937	546	48.18	1	531	1	521	0.0e+00	487	COG0459	Chaperonin GroEL (HSP60 family)	524
644917938	96	69.79	1	96	1	95	1.0e-30	124	COG0234	Co-chaperonin GroES (HSP10)	96
644917939	145	39.31	1	145	2	144	5.0e-28	116	COG3030	Protein affecting phage T7 exclusion by the F plasmid, UPF0716 family	158
644917940	428	22.06	82	427	66	391	5.0e-06	46	COG2814	Predicted arabinose efflux permease, MFS family	394
644917941	279	24.31	1	278	1	278	9.0e-14	71.1	COG3725	Membrane protein required for beta-lactamase induction	282
644917945	177	29.3	14	162	49	205	2.0e-23	102	COG3577	Predicted aspartyl protease	215
644917946	280	47.99	11	278	5	277	4.0e-83	301	COG0157	Nicotinate-nucleotide pyrophosphorylase	280
644917949	166	30.83	3	122	2	118	3.0e-12	65	COG4969	Tfp pilus assembly protein, major pilin PilA	125
644917950	575	47.45	67	575	5	500	0.0e+00	549	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
644917951	404	44.58	8	404	3	396	3.0e-105	375	COG1459	Type II secretory pathway, component PulF	397
644917952	294	41.61	16	288	3	250	1.0e-34	140	COG1989	Prepilin signal peptidase PulO (type II secretory pathway) or related peptidase	254
644917953	202	42.86	1	195	2	197	1.0e-49	189	COG0237	Dephospho-CoA kinase	201
644917954	66	50	1	62	1	64	3.0e-13	67	COG3024	Endogenous inhibitor of DNA gyrase, YacG/DUF329 family	65
644917955	319	30.49	160	316	34	191	6.0e-22	98.4	COG0352	Thiamine monophosphate synthase	211
644917956	405	46.19	1	405	2	404	1.0e-126	446	COG1364	N-acetylglutamate synthase (N-acetylornithine aminotransferase)	404
644917957	911	56.89	2	901	1	820	0.0e+00	1058	COG0653	Preprotein translocase subunit SecA (ATPase, RNA helicase)	822
644917958	310	30.51	67	301	23	257	2.0e-33	136	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
644917959	303	62	1	299	1	298	6.0e-126	443	COG0774	UDP-3-O-acyl-N-acetylglucosamine deacetylase	300
644917960	389	58.54	10	325	10	324	2.0e-99	356	COG0206	Cell division GTPase FtsZ	338
644917961	408	53.11	3	408	1	418	0.0e+00	488	COG0849	Cell division ATPase FtsA	418
644917962	293	22.93	23	284	5	260	3.0e-29	122	COG1589	Cell division septal protein FtsQ	269
644917963	317	42.49	15	309	1	313	9.0e-79	287	COG1181	D-alanine-D-alanine ligase and related ATP-grasp enzymes	317
644917964	473	48.5	9	473	1	459	0.0e+00	569	COG0773	UDP-N-acetylmuramate-alanine ligase	459
644917965	386	45.78	18	378	2	355	4.0e-89	321	COG0707	UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase	357
644917966	379	41.03	14	377	12	374	4.0e-77	282	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
644917967	453	38.85	8	453	7	448	1.0e-104	373	COG0771	UDP-N-acetylmuramoylalanine-D-glutamate ligase	448
644917968	360	45.82	20	360	1	316	2.0e-58	220	COG0472	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase	319
644917969	458	40.23	24	452	27	451	9.0e-103	367	COG0770	UDP-N-acetylmuramyl pentapeptide synthase	451
644917970	509	45.68	31	501	8	475	1.0e-123	437	COG0769	UDP-N-acetylmuramyl tripeptide synthase	475
644917971	554	36.46	1	541	20	596	2.0e-114	406	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
644917972	106	36.47	19	103	19	103	3.0e-14	69.9	COG3116	Cell division protein FtsL, interacts with FtsB, FtsL and FtsQ	105
644917973	311	52.9	6	311	7	312	4.0e-110	391	COG0275	16S rRNA C1402 N4-methylase RsmH	314
644917974	147	40.54	1	147	1	146	1.0e-35	142	COG2001	MraZ, DNA-binding transcriptional regulator and inhibitor of RsmH methyltransferase activity	146
644917978	118	53.27	12	118	4	110	8.0e-36	142	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
644917979	155	30.91	16	125	24	129	4.0e-15	74.6	COG1664	Cytoskeletal protein CcmA, bactofilin family	146
644917981	346	51.85	1	346	2	349	8.0e-117	413	COG0002	N-acetyl-gamma-glutamylphosphate reductase	349
644917982	608	29.46	44	437	17	420	2.0e-56	213	COG0038	H+/Cl- antiporter ClcA	443
644917983	141	53.57	1	138	8	147	3.0e-41	160	COG1981	Uncharacterized membrane protein	149
644917984	280	26.34	7	263	2	261	9.0e-33	134	COG0351	Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase	263
644917985	212	42.51	2	208	1	206	2.0e-48	185	COG0352	Thiamine monophosphate synthase	211
644917986	427	60.75	1	427	4	430	0.0e+00	614	COG0001	Glutamate-1-semialdehyde aminotransferase	432
644917989	330	31.79	57	330	32	307	3.0e-36	146	COG0524	Sugar or nucleoside kinase, ribokinase family	311
644917990	357	29.78	16	356	10	358	4.0e-71	262	COG5345	Uncharacterized protein	358
644917991	145	31.93	25	143	24	141	3.0e-21	94.2	COG2847	Copper(I)-binding protein	151
644917993	599	31.67	17	599	3	569	2.0e-101	363	COG4232	Thiol:disulfide interchange protein	569
644917994	154	60.27	3	148	2	146	5.0e-57	213	COG0757	3-dehydroquinate dehydratase	146
644917995	154	45.27	6	153	1	138	7.0e-25	106	COG0511	Biotin carboxyl carrier protein	140
644917996	446	63.45	1	444	1	445	0.0e+00	619	COG0439	Biotin carboxylase	449
644917997	299	45.82	1	292	2	300	7.0e-83	300	COG2264	Ribosomal protein L11 methylase PrmA	300
644917999	330	45.37	1	321	1	320	2.0e-85	309	COG0042	tRNA-dihydrouridine synthase	323
644918000	103	70.83	32	103	27	98	2.0e-25	107	COG2901	DNA-binding protein Fis (factor for inversion stimulation)	98
644918001	526	65.26	10	526	2	515	0.0e+00	766	COG0138	AICAR transformylase/IMP cyclohydrolase PurH	515
644918002	428	58.88	1	426	1	426	0.0e+00	605	COG0151	Phosphoribosylamine-glycine ligase	428
644918007	926	59.26	10	902	7	859	0.0e+00	1162	COG1048	Aconitase A	861
644918008	452	52.63	3	452	4	459	0.0e+00	589	COG0114	Fumarate hydratase class II	462
644918013	100	39	1	100	2	98	8.0e-21	91.9	COG2329	Heme-degrading monooxygenase HmoA and related ABM domain proteins	105
644918016	477	20.78	8	472	5	466	2.0e-24	106	COG3379	Predicted phosphohydrolase or phosphomutase, AlkP superfamily	471
644918024	97	35.96	1	89	1	85	4.0e-14	69.9	COG1343	CRISPR/Cas system-associated endoribonuclease Cas2	89
644918025	339	35.22	6	337	4	326	5.0e-62	231	COG1518	CRISPR/Cas system-associated endonuclease Cas1	327
644918026	212	24.46	6	189	14	190	4.0e-20	91.6	COG1468	CRISPR/Cas system-associated exonuclease Cas4, RecB family	190
644918027	280	50.99	1	253	1	240	5.0e-75	274	COG3649	CRISPR/Cas system type I-B associated protein Csh2, Cas7 group, RAMP superfamily	283
644918030	818	18.95	66	805	1	727	7.0e-48	186	COG1203	CRISPR/Cas system-associated endonuclease/helicase Cas3	733
644918031	317	23.27	1	317	4	309	6.0e-29	121	COG2378	Predicted DNA-binding transcriptional regulator YafY, contains an HTH and WYL domains	311
644918032	521	36.17	8	505	17	531	1.0e-96	347	COG0659	Sulfate permease or related transporter, MFS superfamily	554
644918033	493	28.38	103	470	114	486	4.0e-49	189	COG0464	AAA+-type ATPase, SpoVK/Ycf46/Vps4 family	494
644918034	213	45.15	8	213	1	204	4.0e-58	217	COG2941	Demethoxyubiquinone hydroxylase, CLK1/Coq7/Cat5 family	204
644918035	139	44.2	1	138	2	137	3.0e-32	130	COG1765	Uncharacterized OsmC-related protein	137
644918036	208	36.18	11	208	17	214	1.0e-37	149	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
644918037	270	55.64	12	268	1	253	2.0e-82	299	COG0134	Indole-3-glycerol phosphate synthase	254
644918038	341	49.71	1	340	2	337	3.0e-106	378	COG0547	Anthranilate phosphoribosyltransferase	338
644918039	194	61.78	1	191	3	189	2.0e-80	292	COG0512	Anthranilate/para-aminobenzoate synthase component II	191
644918042	678	20.99	368	677	10	329	2.0e-22	101	COG0642	Signal transduction histidine kinase	336
644918043	456	43.41	7	453	4	461	1.0e-126	447	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
644918045	492	48.84	18	488	1	454	0.0e+00	498	COG0147	Anthranilate/para-aminobenzoate synthases component I	462
644918046	234	57.01	9	229	1	219	2.0e-83	302	COG0036	Pentose-5-phosphate-3-epimerase	220
644918049	364	34.12	40	347	6	338	2.0e-59	222	COG3178	Predicted phosphotransferase, aminoglycoside/choline kinase (APH/ChoK) family	351
644918050	833	26.8	60	819	17	775	5.0e-109	389	COG1452	LPS assembly outer membrane protein LptD (organic solvent tolerance protein OstA)	784
644918052	327	54.63	2	322	5	328	9.0e-108	383	COG1995	4-hydroxy-L-threonine phosphate dehydrogenase PdxA	332
644918053	267	49.42	10	265	3	256	1.0e-82	299	COG0030	16S rRNA A1518 and A1519 N6-dimethyltransferase RsmA/KsgA/DIM1 (may also have DNA glycosylase/AP lyase activity)	259
644918054	131	55.28	9	131	4	126	7.0e-41	159	COG2967	Uncharacterized protein affecting Mg2+/Co2+ transport	126
644918056	339	49.26	1	337	1	329	0.0e+00	489	COG1087	UDP-glucose 4-epimerase	329
644918057	640	68.1	1	640	1	649	0.0e+00	886	COG2766	Predicted Ser/Thr protein kinase	649
644918058	419	56.16	1	418	1	419	0.0e+00	497	COG2718	Uncharacterized conserved protein YeaH/YhbH, required for sporulation, DUF444 family	423
644918062	411	33.25	1	388	23	402	3.0e-73	269	COG0617	tRNA nucleotidyltransferase/poly(A) polymerase	412
644918063	245	34.68	6	242	5	251	5.0e-39	154	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
644918064	162	38.96	1	150	1	152	6.0e-29	120	COG0801	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase	160
644918065	117	35.34	1	115	2	117	1.0e-25	108	COG1539	Dihydroneopterin aldolase	121
644918066	356	53.49	1	342	1	341	4.0e-125	441	COG0533	tRNA A37 threonylcarbamoyltransferase TsaD	342
644918067	537	30	1	537	4	515	2.0e-83	303	COG1620	L-lactate permease	522
644918068	331	46.79	1	322	1	315	3.0e-90	325	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
644918069	71	59.09	1	66	1	66	6.0e-06	42.6	COG0828	Ribosomal protein S21	67
644918070	149	49.66	3	148	1	147	1.0e-33	135	COG1610	Uncharacterized conserved protein YqeY	148
644918071	313	40.48	20	304	16	285	9.0e-58	217	COG4240	Pantothenate kinase-related protein Tda10 (topoisomerase I damage affected protein)	300
644918072	278	37.96	11	273	7	268	2.0e-39	156	COG3769	Predicted mannosyl-3-phosphoglycerate phosphatase, HAD superfamily	274
644918074	581	20.85	90	538	43	492	3.0e-34	140	COG0366	Glycosidase	505
644918075	290	36.82	1	288	13	307	3.0e-59	222	COG3386	Sugar lactone lactonase YvrE	307
644918076	156	36.02	1	154	1	152	3.0e-16	78	COG2954	CYTH domain, found in class IV adenylate cyclase and various triphosphatases	156
644918077	141	35.04	6	140	3	139	2.0e-24	105	COG4968	Tfp pilus assembly protein PilE	139
644918079	1245	28.66	395	1245	176	1036	2.0e-104	374	COG3419	Tfp pilus assembly protein, tip-associated adhesin PilY1	1036
644918080	177	22.89	5	176	7	194	3.0e-17	82	COG4726	Tfp pilus assembly protein PilX	196
644918081	373	19.06	1	329	5	312	2.0e-15	77	COG4966	Tfp pilus assembly protein PilW	318
644918082	170	25.49	10	162	7	153	2.0e-13	68.9	COG4967	Tfp pilus assembly protein PilV	162
644918083	219	29.48	32	201	2	173	6.0e-21	94.3	COG4970	Tfp pilus assembly protein FimT	181
644918085	390	24.63	1	388	1	398	1.0e-20	94.3	COG1668	ABC-type Na+ efflux pump, permease component	407
644918086	250	46.09	1	243	1	238	3.0e-71	261	COG4555	ABC-type Na+ transport system, ATPase component NatA	245
644918088	327	41.67	7	327	2	322	2.0e-87	316	COG2896	Molybdenum cofactor biosynthesis enzyme MoaA	322
644918089	169	48.47	9	169	5	166	2.0e-50	191	COG0521	Molybdopterin biosynthesis enzyme MoaB	169
644918090	190	27.45	14	166	3	144	8.0e-15	73.8	COG1403	5-methylcytosine-specific restriction endonuclease McrA	146
644918092	329	30.5	7	287	5	243	1.0e-44	174	COG1360	Flagellar motor protein MotB	244
644918093	253	37.05	1	247	1	251	1.0e-56	213	COG1291	Flagellar motor component MotA	266
644918094	80	42.31	1	78	4	81	3.0e-11	60	COG1722	Exonuclease VII small subunit	81
644918095	130	63.55	1	107	1	107	3.0e-45	173	COG0139	Phosphoribosyl-AMP cyclohydrolase	111
644918096	110	55.21	5	100	1	91	2.0e-22	97.2	COG0140	Phosphoribosyl-ATP pyrophosphohydrolase	92
644918097	80	38.46	3	80	1	78	2.0e-12	64.2	COG1826	Sec-independent protein translocase protein TatA	94
644918098	128	24.24	1	99	1	94	8.0e-13	66.1	COG1826	Sec-independent protein translocase protein TatA	94
644918099	255	48.95	11	244	6	242	6.0e-58	217	COG0805	Sec-independent protein secretion pathway component TatC	255
644918100	323	23.78	13	294	1	262	2.0e-18	86.7	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
644918101	446	28.33	128	423	35	328	3.0e-33	136	COG0642	Signal transduction histidine kinase	336
644918102	229	46.49	4	228	3	229	2.0e-60	225	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
644918104	371	23.11	110	371	31	258	4.0e-15	76.1	COG3713	Outer membrane scaffolding protein for murein synthesis, MipA/OmpV family	258
644918105	145	57.93	1	145	1	145	2.0e-56	211	COG1490	D-Tyr-tRNAtyr deacylase	145
644918106	247	38	2	247	4	248	1.0e-60	226	COG1540	Lactam utilization protein B (function unknown)	252
644918107	231	37	5	228	2	222	2.0e-43	168	COG2049	Allophanate hydrolase subunit 1	223
644918108	288	38.75	5	286	1	288	2.0e-68	252	COG1984	Allophanate hydrolase subunit 2	314
644918109	744	44.53	490	744	1	254	5.0e-73	269	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
644918111	727	33.76	28	404	1	372	4.0e-73	269	COG1472	Periplasmic beta-glucosidase and related glycosidases	397
644918113	275	18.77	9	266	13	258	7.0e-11	61.5	COG3713	Outer membrane scaffolding protein for murein synthesis, MipA/OmpV family	258
644918114	705	63.11	1	694	2	692	0.0e+00	1005	COG1185	Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase)	692
644918115	89	57.3	1	89	1	89	1.0e-26	111	COG0184	Ribosomal protein S15P/S13E	89
644918116	313	39.67	12	311	15	270	2.0e-66	245	COG0130	tRNA U55 pseudouridine synthase TruB, may also work on U342 of tmRNA	271
644918117	132	41.23	7	120	6	118	8.0e-24	102	COG0858	Ribosome-binding factor A	118
644918118	940	59.37	439	940	1	507	0.0e+00	627	COG0532	Translation initiation factor IF-2, a GTPase	509
644918119	496	51.6	159	345	1	182	2.0e-47	183	COG0195	Transcription antitermination factor NusA, contains S1 and KH domains	190
644918120	152	50	7	152	9	153	8.0e-42	162	COG0779	Ribosome maturation factor RimP	153
644918122	345	40.25	180	336	16	172	9.0e-25	107	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
644918127	135	28.1	14	132	13	132	2.0e-12	64.9	COG0848	Biopolymer transport protein ExbD	137
644918129	436	30.35	237	432	12	208	2.0e-23	103	COG0811	Biopolymer transport protein ExbB/TolQ	216
644918131	334	41.27	9	332	7	337	2.0e-81	296	COG1816	Adenosine deaminase	345
644918133	234	26.17	1	210	11	220	2.0e-14	72.6	COG0398	Uncharacterized membrane protein YdjX, TVP38/TMEM64 family, SNARE-associated domain	223
644918134	375	15.26	3	370	15	378	1.0e-05	44.9	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
644918136	788	21.96	132	775	140	782	2.0e-28	121	COG4258	Predicted exporter	788
644918138	230	19.71	9	216	10	200	7.0e-13	67.7	COG2834	Outer membrane lipoprotein-sorting protein	211
644918139	282	22.28	34	196	7	191	4.0e-16	78.8	COG3394	Predicted glycoside hydrolase or deacetylase ChbG, UPF0249 family	257
644918141	671	30.43	108	664	1	509	1.0e-68	254	COG1657	Squalene cyclase	517
644918142	375	22.59	32	301	16	250	1.0e-21	97.7	COG1562	Phytoene/squalene synthetase	288
644918143	218	20.5	1	149	3	202	7.0e-06	44.2	COG0775	Nucleoside phosphorylase	234
644918144	341	27.03	4	322	2	308	1.0e-33	137	COG0451	Nucleoside-diphosphate-sugar epimerase	314
644918145	335	36.02	7	326	4	317	1.0e-67	250	COG3407	Mevalonate pyrophosphate decarboxylase	329
644918146	346	23.91	7	328	3	297	2.0e-27	116	COG1577	Mevalonate kinase	307
644918147	432	34.62	1	430	7	436	3.0e-92	332	COG1257	Hydroxymethylglutaryl-CoA reductase	436
644918148	318	38.28	12	307	4	297	4.0e-53	201	COG1577	Mevalonate kinase	307
644918149	196	38.18	16	175	3	167	3.0e-39	154	COG1443	Isopentenyldiphosphate isomerase	185
644918150	372	24.43	21	316	12	316	1.0e-21	97.8	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
644918152	295	37.62	32	295	28	322	6.0e-61	227	COG0142	Geranylgeranyl pyrophosphate synthase	322
644918156	447	20.99	28	285	102	355	1.0e-07	51.6	COG2273	Beta-glucanase, GH16 family	355
644918157	493	22.63	128	492	13	388	3.0e-40	159	COG1680	CubicO group peptidase, beta-lactamase class C family	390
644918159	148	45.12	1	82	1	81	7.0e-16	76.4	COG1314	Preprotein translocase subunit SecG	86
644918160	246	52.61	1	245	1	247	7.0e-81	293	COG0149	Triosephosphate isomerase	251
644918161	446	45.41	1	441	5	457	2.0e-115	409	COG1109	Phosphomannomutase	464
644918162	305	50.38	36	296	8	261	2.0e-66	246	COG0294	Dihydropteroate synthase	274
644918163	638	59.77	9	602	1	596	0.0e+00	773	COG0465	ATP-dependent Zn proteases	596
644918164	206	60.59	4	206	1	203	7.0e-75	273	COG0293	23S rRNA U2552 (ribose-2'-O)-methylase RlmE/FtsJ	205
644918165	99	40.7	2	87	1	86	2.0e-17	80.2	COG1534	RNA-binding protein YhbY	97
644918166	473	29.85	139	471	4	330	2.0e-41	164	COG0642	Signal transduction histidine kinase	336
644918167	232	38.86	5	231	3	229	3.0e-56	212	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
644918171	393	35.63	5	392	7	409	3.0e-75	275	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
644918172	310	35.95	10	310	4	304	2.0e-60	225	COG4261	Predicted acyltransferase, LPLAT superfamily	309
644918174	442	21.74	9	438	21	525	2.0e-24	107	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
644918177	275	34.47	49	275	7	237	6.0e-38	151	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
644918178	299	28.16	198	294	26	123	7.0e-08	51.4	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
644918179	262	28.34	34	210	7	193	4.0e-15	75.3	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
644918180	104	35.14	7	80	4	77	3.0e-09	53.4	COG0236	Acyl carrier protein	80
644918182	250	18.82	8	246	7	255	6.0e-06	44.7	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
644918183	139	33.6	13	136	10	131	7.0e-22	96.5	COG0824	Acyl-CoA thioesterase FadM	137
644918185	794	28.76	125	767	117	772	9.0e-54	205	COG4258	Predicted exporter	788
644918186	159	28.38	14	159	8	155	7.0e-21	93.2	COG4706	Predicted 3-hydroxylacyl-ACP dehydratase, HotDog domain	161
644918187	240	41.04	1	239	4	250	5.0e-41	161	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
644918188	412	42.48	4	408	3	410	3.0e-108	385	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
644918190	158	52.94	6	158	1	151	9.0e-40	156	COG0782	Transcription elongation factor, GreA/GreB family	151
644918191	1073	70.47	13	415	1	400	0.0e+00	585	COG0458	Carbamoylphosphate synthase large subunit	400
644918192	386	59.84	10	384	1	368	0.0e+00	565	COG0505	Carbamoylphosphate synthase small subunit	368
644918193	268	58.05	1	267	1	266	3.0e-90	324	COG0289	Dihydrodipicolinate reductase	266
644918194	376	62.77	1	373	1	371	0.0e+00	487	COG0484	DnaJ-class molecular chaperone with C-terminal Zn finger domain	371
644918195	644	62.38	1	605	4	579	0.0e+00	670	COG0443	Molecular chaperone DnaK (HSP70)	579
644918196	190	43.39	2	190	3	191	2.0e-40	158	COG0576	Molecular chaperone GrpE (heat shock protein)	193
644918197	552	45.78	1	552	1	555	0.0e+00	548	COG0497	DNA repair ATPase RecN	557
644918198	137	44.8	6	130	10	133	1.0e-33	135	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
644918199	156	31.75	1	121	4	128	3.0e-23	101	COG2913	Outer membrane protein assembly factor BamE, lipoprotein component of the BamABCDE complex	147
644918200	107	44.55	5	105	2	95	1.0e-19	88.4	COG2914	Putative antitoxin component PasI (RatB) of the RatAB toxin-antitoxin module, ubiquitin-RnfH superfamily	99
644918201	146	47.55	3	144	2	144	8.0e-42	162	COG2867	Ribosome association toxin PasT (RatA) of the RatAB toxin-antitoxin module	146
644918202	449	40.67	2	445	5	435	2.0e-89	323	COG0733	Na+-dependent transporter, SNF family	439
644918204	158	57.79	5	158	1	153	3.0e-51	194	COG0691	tmRNA-binding protein	153
644918206	100	39.18	1	96	1	94	1.0e-18	84.6	COG4680	mRNA-degrading endonuclease (mRNA interferase) HigB, toxic component of the HigAB toxin-antitoxin module	98
644918207	122	48.28	3	116	5	120	2.0e-27	114	COG5499	Antitoxin component HigA of the HigAB toxin-antitoxin module, contains an N-terminal HTH domain	120
644918208	446	23.64	77	401	11	283	9.0e-16	78.4	COG0502	Biotin synthase or related enzyme	335
644918210	242	38.89	2	198	1	195	8.0e-47	180	COG0518	GMP synthase - Glutamine amidotransferase domain	198
644918211	233	42.58	3	211	2	208	2.0e-47	182	COG2258	Uncharacterized conserved protein YiiM, contains MOSC domain	210
644918212	305	33.44	1	296	1	295	8.0e-37	147	COG0583	DNA-binding transcriptional regulator, LysR family	297
644918215	426	54.93	1	426	1	404	0.0e+00	505	COG4277	Predicted DNA-binding protein with the Helix-hairpin-helix motif	404
644918216	160	42.48	6	158	4	154	2.0e-35	141	COG1522	DNA-binding transcriptional regulator, Lrp family	154
644918217	579	32.77	29	436	1	381	4.0e-93	336	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
644918218	339	25.56	1	337	1	351	2.0e-45	176	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
644918219	314	41.19	1	306	3	320	2.0e-65	243	COG1270	Cobalamin biosynthesis protein CobD/CbiB	320
644918222	1483	30.61	184	1448	124	1338	0.0e+00	732	COG1429	Cobalamin biosynthesis protein CobN, Mg-chelatase	1388
644918223	282	38.6	1	280	1	284	2.0e-48	185	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
644918224	274	37.6	12	249	11	239	3.0e-47	181	COG3384	Aromatic ring-opening dioxygenase, catalytic subunit, LigB family	268
644918225	315	55.56	1	313	3	311	8.0e-118	416	COG0435	Glutathionyl-hydroquinone reductase	324
644918226	163	48.09	13	142	11	136	1.0e-13	69.3	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
644918230	296	34.12	3	293	2	297	2.0e-41	162	COG0583	DNA-binding transcriptional regulator, LysR family	297
644918233	317	31.31	9	299	11	285	5.0e-50	191	COG4974	Site-specific recombinase XerD	300
644918234	405	23.81	1	398	6	422	6.0e-52	198	COG0738	Fucose permease	422
644918235	503	15.77	8	438	17	451	1.0e-19	92	COG0366	Glycosidase	505
644918236	296	28.12	6	296	8	312	2.0e-32	133	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
644918237	816	17.93	11	816	29	768	3.0e-19	90.8	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
644918238	341	35.01	12	341	2	329	8.0e-65	241	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
644918240	509	30.04	223	501	3	269	9.0e-33	135	COG0388	Predicted amidohydrolase	274
644918241	411	31.13	91	408	49	341	4.0e-60	225	COG3693	Endo-1,4-beta-xylanase, GH35 family	345
644918242	1430	22.97	3	559	4	507	2.0e-48	188	COG3227	Zn-dependent metalloprotease	507
644918243	848	20.08	14	793	9	666	1.0e-34	142	COG4771	Outer membrane receptor for ferrienterochelin and colicins	699
644918250	385	34.31	282	383	25	124	2.0e-14	73.4	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
644918251	650	16.23	269	627	19	371	3.0e-13	70.9	COG2730	Aryl-phospho-beta-D-glucosidase BglC, GH1 family	407
644918254	547	32.2	82	376	117	408	5.0e-37	149	COG0840	Methyl-accepting chemotaxis protein	408
644918257	610	32.09	21	605	4	550	2.0e-106	380	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
644918258	718	23.49	51	717	37	698	3.0e-45	177	COG4771	Outer membrane receptor for ferrienterochelin and colicins	699
644918259	135	22.11	2	96	4	95	2.0e-06	45.4	COG2314	Uncharacterized membrane protein YozV, TM2 domain	95
644918260	169	35.58	3	165	6	162	5.0e-31	127	COG3542	Predicted sugar epimerase, cupin superfamily	162
644918261	399	36.29	9	395	1	391	5.0e-90	324	COG1092	23S rRNA G2069 N7-methylase RlmK or C1962 C5-methylase RlmI	393
644918262	279	41.99	2	278	1	279	5.0e-69	254	COG2961	23S rRNA A2030 N6-methylase RlmJ	279
644918264	476	25.83	3	464	4	446	9.0e-57	214	COG0527	Aspartokinase	447
644918266	431	37.39	1	413	19	445	1.0e-113	403	COG0160	4-aminobutyrate aminotransferase or related aminotransferase	447
644918268	178	31.97	26	147	1	122	5.0e-10	57.6	COG1846	DNA-binding transcriptional regulator, MarR family	126
644918269	301	36.28	1	291	1	316	7.0e-64	237	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
644918270	348	33.22	34	314	37	325	1.0e-45	177	COG3608	Predicted deacylase	331
644918271	146	39.13	3	138	22	158	2.0e-31	128	COG4067	Uncharacterized conserved protein	162
644918274	151	30.34	6	150	1	139	1.0e-18	85.8	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
644918276	238	44.54	14	237	2	229	8.0e-60	223	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
644918277	424	27.7	136	424	40	329	2.0e-29	124	COG0642	Signal transduction histidine kinase	336
644918279	193	54.59	8	190	3	187	4.0e-73	267	COG2818	3-methyladenine DNA glycosylase Tag	188
644918280	290	22.82	39	234	17	221	3.0e-15	76	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
644918281	204	40.83	36	202	1	169	5.0e-37	147	COG1247	L-amino acid N-acyltransferase YncA	169
644918282	381	34.18	61	374	57	337	1.0e-61	230	COG3693	Endo-1,4-beta-xylanase, GH35 family	345
644918285	346	57.35	1	339	2	341	4.0e-114	404	COG0709	Selenophosphate synthase	346
644918286	362	43.53	3	339	5	334	2.0e-72	266	COG2603	tRNA 2-selenouridine synthase SelU, contains rhodanese domain	334
644918287	105	29.41	12	105	1	102	7.0e-14	68.8	COG2329	Heme-degrading monooxygenase HmoA and related ABM domain proteins	105
644918288	524	16.13	283	499	4	166	5.0e-08	53.1	COG0622	Predicted phosphodiesterase	172
644918290	130	30.97	10	122	1	113	7.0e-09	52.9	COG2018	Predicted regulator of Ras-like GTPase activity, Roadblock/LC7/MglB family	119
644918291	175	36.57	1	175	8	180	2.0e-29	122	COG2229	Signal recognition particle receptor subunit beta, a GTPase	187
644918293	588	36.34	1	383	3	386	1.0e-56	214	COG0475	Kef-type K+ transport system, membrane component KefB	397
644918294	547	60.69	26	546	2	524	0.0e+00	674	COG0033	Phosphoglucomutase	524
644918298	167	29.03	20	154	11	165	5.0e-18	84.3	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
644918300	515	52.05	5	416	2	409	2.0e-120	426	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
644918301	238	41.7	5	236	7	237	3.0e-62	231	COG0217	Transcriptional and/or translational regulatory protein YebC/TACO1	241
644918302	352	47.2	30	350	20	324	3.0e-107	381	COG0379	Quinolinate synthase	324
644918304	224	54.22	1	222	1	219	5.0e-74	270	COG0603	7-cyano-7-deazaguanine synthase (queuosine biosynthesis)	222
644918305	214	32.13	1	210	1	212	2.0e-37	149	COG0602	Organic radical activating enzyme	212
644918306	254	26.29	4	231	11	239	1.0e-23	103	COG1729	Periplasmic TolA-binding protein (function unknown)	262
644918308	431	42.29	5	428	1	424	1.0e-91	330	COG0823	Periplasmic component of the Tol biopolymer transport system	425
644918309	250	17.27	8	222	5	223	3.0e-07	49	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
644918310	139	42.75	2	139	6	137	7.0e-27	113	COG0848	Biopolymer transport protein ExbD	137
644918311	229	41.4	11	225	1	213	5.0e-50	190	COG0811	Biopolymer transport protein ExbB/TolQ	216
644918312	137	39.26	1	135	3	137	1.0e-30	125	COG0824	Acyl-CoA thioesterase FadM	137
644918313	347	68.58	4	334	1	331	0.0e+00	531	COG2255	Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit	332
644918314	206	39.02	1	203	1	200	3.0e-49	188	COG0632	Holliday junction resolvasome RuvABC DNA-binding subunit	201
644918315	177	54.27	5	168	1	160	2.0e-50	191	COG0817	Holliday junction resolvasome RuvABC endonuclease subunit	160
644918329	3177	35.71	2999	3177	9	188	5.0e-26	115	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
644918333	802	24.92	198	769	4	622	9.0e-60	225	COG1199	Rad3-related DNA helicase	654
644918339	68	61.11	1	54	1	54	2.0e-14	70.8	COG3205	Uncharacterized membrane protein	72
644918340	270	32.49	12	245	1	233	5.0e-41	161	COG2908	UDP-2,3-diacylglucosamine pyrophosphatase LpxH	237
644918342	845	14.65	88	845	42	768	3.0e-12	67.6	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
644918343	464	32.52	88	314	71	312	7.0e-36	145	COG0226	ABC-type phosphate transport system, periplasmic component	318
644918346	418	46.69	126	412	2	283	1.0e-87	316	COG2230	Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases	283
644918347	258	31.98	5	248	4	244	2.0e-46	179	COG3496	Uncharacterized conserved protein, DUF1365 family	261
644918348	417	42.76	1	417	9	426	4.0e-126	444	COG2907	Predicted NAD/FAD-binding protein	447
644918349	251	27.52	5	250	6	262	2.0e-38	153	COG0300	Short-chain dehydrogenase	265
644918351	192	30.36	20	187	7	172	3.0e-26	111	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
644918352	228	32.44	2	222	1	215	2.0e-30	126	COG3806	Anti-sigma factor ChrR, cupin superfamily	216
644918353	315	40.51	158	315	1	158	1.0e-38	153	COG3272	Uncharacterized conserved protein YbgA, DUF1722 family	163
644918355	1547	36.75	8	289	10	290	7.0e-57	217	COG3452	Extracellular (periplasmic) sensor domain CHASE (specificity unknown)	297
644918357	369	22.22	4	329	2	312	9.0e-21	94.9	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
644918358	274	30.65	9	269	7	257	1.0e-34	139	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
644918359	264	42.98	1	235	1	219	1.0e-64	239	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
644918360	244	26.96	14	211	51	248	1.0e-24	106	COG3665	Uncharacterized conserved protein YcgI, DUF1989 family	264
644918361	211	37.81	17	211	50	247	4.0e-43	167	COG3665	Uncharacterized conserved protein YcgI, DUF1989 family	264
644918363	606	33.48	8	451	6	464	7.0e-80	292	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
644918365	935	37.54	177	830	174	786	2.0e-110	394	COG2374	Predicted extracellular nuclease	798
644918367	147	48.3	1	147	2	146	3.0e-42	164	COG1671	Uncharacterized conserved protein YaiI, UPF0178 family	150
644918368	138	34.56	2	136	1	132	2.0e-20	91.6	COG3791	Uncharacterized conserved protein	133
644918371	1195	39.33	7	393	2	364	8.0e-95	342	COG0674	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, alpha subunit	365
644918372	542	34.05	35	420	30	449	2.0e-77	284	COG0493	NADPH-dependent glutamate synthase beta chain or related oxidoreductase	457
644918373	241	46.45	10	164	5	151	1.0e-38	153	COG1720	tRNA (Thr-GGU) A37 N-methylase	156
644918374	268	26.42	29	268	47	262	1.0e-14	73.5	COG3137	Putative salt-induced outer membrane protein YdiY	262
644918377	325	30	57	296	54	281	4.0e-29	122	COG0223	Methionyl-tRNA formyltransferase	307
644918378	195	35.38	1	195	1	170	7.0e-32	130	COG4675	Microcystin-dependent protein  (function unknown)	170
644918383	291	28.38	1	288	10	309	6.0e-29	121	COG1305	Transglutaminase-like enzyme, putative cysteine protease	319
644918384	258	28.75	18	94	1	76	2.0e-09	56.1	COG0695	Glutaredoxin	80
644918390	641	29.18	264	640	37	408	4.0e-46	179	COG0840	Methyl-accepting chemotaxis protein	408
644918391	162	66.45	11	162	3	154	4.0e-58	217	COG3558	Uncharacterized conserved protein, nuclear transport factor 2 (NTF2) superfamily	154
644918392	305	22.99	12	178	5	173	7.0e-14	71.6	COG3576	Predicted flavin-nucleotide-binding protein, pyridoxine 5'-phosphate oxidase superfamily	173
644918393	159	32.37	15	146	4	139	5.0e-06	44.2	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
644918395	295	37.23	18	289	7	270	1.0e-61	230	COG3220	Uncharacterized conserved protein, UPF0276 family	282
644918396	95	48.15	1	76	12	91	1.0e-08	51.3	COG5572	Uncharacterized membrane protein	104
644918398	181	32.9	25	171	22	176	1.0e-08	53.3	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
644918399	342	33	47	340	3	296	1.0e-38	154	COG0583	DNA-binding transcriptional regulator, LysR family	297
644918400	213	22.84	24	184	21	182	2.0e-20	92.5	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
644918401	345	31.29	1	342	1	318	6.0e-54	205	COG3712	Periplasmic ferric-dicitrate binding protein FerR, regulates iron transport through sigma-19	322
644918402	1028	17.34	365	1028	175	768	1.0e-17	86.5	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
644918404	146	26.49	1	145	1	149	3.0e-14	70.8	COG0716	Flavodoxin	151
644918406	380	21.9	41	376	118	449	2.0e-17	83.9	COG1231	Monoamine oxidase	450
644918408	217	32.64	13	203	5	191	9.0e-29	120	COG1896	5'-deoxynucleotidase YfbR and related HD superfamily hydrolases	193
644918410	256	29.08	2	247	1	251	3.0e-16	79.3	COG0730	Uncharacterized membrane protein YfcA	258
644918411	184	30	1	139	1	131	3.0e-17	81.6	COG0716	Flavodoxin	151
644918413	75	66.18	2	69	1	68	2.0e-22	97.3	COG3530	Uncharacterized conserved protein, DUF3820 family	71
644918414	160	65.43	1	160	4	165	1.0e-57	215	COG1666	Uncharacterized conserved protein YajQ, UPF0234 family	165
644918415	103	38.46	1	89	1	91	1.0e-11	61.8	COG1544	Ribosome-associated translation inhibitor RaiA	110
644918417	186	39.46	9	155	11	156	3.0e-38	151	COG1607	Acyl-CoA hydrolase	157
644918418	321	38.08	21	292	2	266	3.0e-59	222	COG2041	Periplasmic DMSO/TMAO reductase YedYZ, molybdopterin-dependent catalytic subunit	271
644918419	196	41.84	1	196	6	201	5.0e-35	141	COG2717	Periplasmic DMSO/TMAO reductase YedYZ, heme-binding membrane subunit	209
644918420	333	22.33	7	314	2	297	2.0e-29	123	COG0583	DNA-binding transcriptional regulator, LysR family	297
644918422	430	62.09	2	430	1	430	0.0e+00	641	COG0104	Adenylosuccinate synthase	430
644918423	394	34.78	5	393	1	386	7.0e-74	271	COG3705	ATP phosphoribosyltransferase regulatory subunit HisZ	390
644918424	61	36.07	1	61	1	61	2.0e-10	57.2	COG3242	Uncharacterized conserved protein YjeT, DUF2065 family	62
644918426	290	28.57	5	284	3	283	4.0e-43	168	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
644918427	385	30.48	63	345	3	290	2.0e-43	170	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
644918428	444	50.24	9	418	3	405	6.0e-126	444	COG2262	50S ribosomal subunit-associated GTPase HflX	411
644918429	87	76.06	1	70	1	71	6.0e-25	105	COG1923	sRNA-binding regulator protein Hfq	77
644918430	323	50.8	6	318	1	308	8.0e-98	350	COG0324	tRNA A37 N6-isopentenylltransferase MiaA	308
644918431	613	45.94	1	612	1	638	0.0e+00	679	COG0323	DNA mismatch repair ATPase MutL	638
644918432	450	32.97	110	385	3	229	4.0e-49	189	COG0860	N-acetylmuramoyl-L-alanine amidase	231
644918433	168	49.66	18	163	3	149	2.0e-41	161	COG0802	tRNA A37 threonylcarbamoyladenosine biosynthesis protein TsaE	149
644918434	507	47.16	231	507	5	282	2.0e-61	230	COG0063	NAD(P)H-hydrate repair enzyme Nnr, NAD(P)H-hydrate dehydratase domain	284
644918435	392	46.38	22	365	1	337	1.0e-102	366	COG1600	Epoxyqueuosine reductase  QueG (queuosine biosynthesis)	337
644918436	628	25.67	243	593	47	393	2.0e-32	134	COG2730	Aryl-phospho-beta-D-glucosidase BglC, GH1 family	407
644918437	410	20.68	17	375	31	409	1.0e-09	58.3	COG2271	Sugar phosphate permease	448
644918439	182	70	1	180	1	180	5.0e-82	296	COG1949	Oligoribonuclease (3'-5' exoribonuclease)	184
644918440	328	36.88	19	319	1	292	1.0e-81	296	COG1162	Putative ribosome biogenesis GTPase RsgA	301
644918441	277	33.45	1	276	4	284	3.0e-57	215	COG2897	3-mercaptopyruvate sulfurtransferase SseA, contains two rhodanese domains	285
644918442	289	34.06	8	278	1	239	1.0e-50	193	COG0688	Phosphatidylserine decarboxylase	239
644918443	459	28.84	59	370	25	343	3.0e-39	156	COG2206	HD-GYP domain, c-di-GMP phosphodiesterase class II (or its inactivated variant)	344
644918445	354	56.94	1	352	2	352	2.0e-128	452	COG0407	Uroporphyrinogen-III decarboxylase	352
644918446	472	45.3	26	472	1	452	0.0e+00	486	COG0493	NADPH-dependent glutamate synthase beta chain or related oxidoreductase	457
644918447	1481	57.94	694	1173	2	485	0.0e+00	633	COG0069	Glutamate synthase domain 2	485
644918449	361	57.78	1	359	1	358	0.0e+00	476	COG0337	3-dehydroquinate synthetase	360
644918450	169	51.48	1	169	1	168	2.0e-53	201	COG0703	Shikimate kinase	172
644918451	727	30.55	17	723	16	709	1.0e-102	368	COG4796	Type II secretory pathway, component HofQ	709
644918452	176	39.05	7	175	3	169	1.0e-35	142	COG3168	Tfp pilus assembly protein PilP	170
644918453	207	42.71	9	207	1	199	2.0e-51	195	COG3167	Tfp pilus assembly protein PilO	211
644918454	186	33.54	1	164	4	167	2.0e-30	125	COG3166	Tfp pilus assembly protein PilN	206
644918455	355	48.86	4	354	2	353	4.0e-100	358	COG4972	Tfp pilus assembly protein, ATPase PilM	354
644918456	840	45.01	9	832	20	783	0.0e+00	852	COG5009	Membrane carboxypeptidase/penicillin-binding protein	797
644918457	69	55.56	1	69	1	72	1.0e-18	84.5	COG0254	Ribosomal protein L31	75
644918458	739	44.44	8	739	3	730	0.0e+00	747	COG1198	Primosomal protein N' (replication factor Y) - superfamily II helicase	730
644918460	194	18.3	7	191	44	264	2.0e-14	72.8	COG3087	Cell division protein FtsN	264
644918461	179	72.88	3	179	1	177	5.0e-77	280	COG5405	ATP-dependent protease HslVU (ClpYQ), peptidase subunit	178
644918462	438	69.37	1	438	1	444	0.0e+00	673	COG1220	ATP-dependent protease HslVU (ClpYQ), ATPase subunit	444
644918463	126	52.78	2	108	4	111	8.0e-36	142	COG3536	Uncharacterized conserved protein, DUF971 family	120
644918464	249	59.83	11	248	1	237	2.0e-85	308	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
644918465	212	25.12	13	209	3	201	5.0e-18	84.6	COG3165	Ubiquinone biosynthesis protein UbiJ, contains SCP2 domain	204
644918466	545	42.11	1	524	4	517	0.0e+00	467	COG0661	Predicted unusual protein kinase regulating ubiquinone biosynthesis, AarF/ABC1/UbiB family	517
644918467	564	29.72	44	564	63	594	2.0e-79	290	COG0729	Outer membrane translocation and assembly module TamA	594
644918468	1197	21.18	130	1172	232	1274	6.0e-78	286	COG2911	Autotransporter translocation and assembly factor TamB	1278
644918471	952	30.06	672	952	33	343	3.0e-51	197	COG3693	Endo-1,4-beta-xylanase, GH35 family	345
644918472	241	30.99	10	239	20	255	3.0e-34	138	COG1877	Trehalose-6-phosphatase	266
644918473	597	26.32	8	591	19	606	1.0e-71	264	COG3387	Glucoamylase (glucan-1,4-alpha-glucosidase), GH15 family	612
644918474	473	41.56	1	459	14	486	1.0e-126	447	COG0380	Trehalose-6-phosphate synthase	486
644918475	666	31.22	7	587	1	517	6.0e-93	335	COG0737	2',3'-cyclic-nucleotide 2'-phosphodiesterase/5'- or 3'-nucleotidase, 5'-nucleotidase family	517
644918478	241	26.8	7	239	7	252	5.0e-27	114	COG0584	Glycerophosphoryl diester phosphodiesterase	257
644918479	623	27.04	7	623	1	608	1.0e-67	251	COG4206	Outer membrane cobalamin receptor protein	608
644918480	486	50.21	1	480	1	482	0.0e+00	589	COG1492	Cobyric acid synthase	486
644918481	166	50.57	1	166	1	174	7.0e-55	206	COG2087	Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase	175
644918482	354	36.18	7	353	5	336	6.0e-61	228	COG2038	NaMN:DMB phosphoribosyltransferase	347
644918483	210	33	10	204	3	202	3.0e-33	134	COG0406	Broad specificity phosphatase PhoE	208
644918484	256	29.02	1	254	1	245	2.0e-22	99.5	COG0368	Cobalamin synthase	246
644918485	310	30.34	5	282	3	291	6.0e-38	151	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
644918486	464	28.07	10	461	1	453	4.0e-37	149	COG1538	Outer membrane protein TolC	457
644918487	652	51.98	7	231	1	226	9.0e-81	295	COG1136	ABC-type lipoprotein export system, ATPase component	226
644918488	437	25.08	11	325	6	308	1.0e-24	107	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
644918489	219	27.6	30	219	26	216	1.0e-15	76.9	COG3235	Uncharacterized membrane protein	223
644918490	442	42.92	1	438	4	454	3.0e-119	422	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
644918494	663	34.31	70	374	38	328	8.0e-42	165	COG0642	Signal transduction histidine kinase	336
644918499	343	25.15	4	336	14	344	5.0e-29	122	COG0628	Predicted PurR-regulated permease PerM	355
644918500	242	29.87	87	239	51	195	6.0e-15	74.6	COG2823	Osmotically-inducible protein OsmY, contains BON domain	196
644918521	279	52.17	1	276	4	273	5.0e-91	327	COG0313	16S rRNA C1402 (ribose-2'-O) methylase RsmI	275
644918522	624	29.16	7	608	11	598	2.0e-85	310	COG3107	Outer membrane lipoprotein LpoA, binds and activates PBP1a	604
644918523	129	44.25	18	129	1	113	6.0e-31	126	COG0792	Predicted endonuclease distantly related to archaeal Holliday junction resolvase	114
644918524	194	44.69	1	179	1	176	7.0e-44	170	COG0279	Phosphoheptose isomerase	176
644918525	191	30.21	1	191	5	196	2.0e-26	111	COG2823	Osmotically-inducible protein OsmY, contains BON domain	196
644918526	392	42.72	2	392	1	392	8.0e-78	284	COG0183	Acetyl-CoA acetyltransferase	392
644918528	251	41.88	59	249	5	185	2.0e-44	172	COG1704	Uncharacterized conserved protein	185
644918529	636	25.08	12	341	9	294	1.0e-22	101	COG0501	Zn-dependent protease with chaperone function	302
644918532	131	53.9	1	131	3	155	5.0e-43	166	COG2969	Stringent starvation protein B	155
644918533	213	28.37	10	211	1	211	1.0e-28	119	COG0625	Glutathione S-transferase	211
644918534	683	48.03	5	409	4	380	8.0e-101	361	COG1290	Cytochrome b subunit of the bc complex	381
644918535	199	38.58	1	197	2	169	5.0e-33	134	COG0723	Rieske Fe-S protein	177
644918536	130	60	1	130	1	130	9.0e-45	172	COG0103	Ribosomal protein S9	130
644918537	142	62.24	1	142	1	143	3.0e-54	203	COG0102	Ribosomal protein L13	148
644918538	377	50.27	1	376	6	367	6.0e-124	437	COG1485	Predicted ATPase	367
644918539	167	27.74	20	149	12	138	2.0e-13	68.9	COG3105	Uncharacterized membrane-anchored protein YhcB, DUF1043 family	138
644918540	385	44.82	60	385	34	345	2.0e-62	233	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
644918541	254	36.4	17	254	1	232	2.0e-57	216	COG0479	Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit	234
644918542	668	43.77	1	589	2	562	0.0e+00	505	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
644918547	308	22.62	58	307	48	287	6.0e-08	51.8	COG5006	Threonine/homoserine efflux transporter RhtA	292
644918549	401	35.6	137	384	1	248	1.0e-48	187	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
644918551	199	59.79	1	194	1	193	7.0e-68	249	COG0807	GTP cyclohydrolase II	193
644918552	207	31.84	11	203	13	213	2.0e-25	108	COG3577	Predicted aspartyl protease	215
644918553	160	45.58	4	147	7	152	6.0e-29	120	COG1267	Phosphatidylglycerophosphatase A	160
644918554	315	45.62	1	314	1	317	6.0e-79	287	COG0611	Thiamine monophosphate kinase	317
644918555	147	48.98	1	141	3	149	5.0e-36	143	COG0781	Transcription termination factor NusB	151
644918556	155	61.84	3	154	1	152	7.0e-53	199	COG0054	6,7-dimethyl-8-ribityllumazine synthase (Riboflavin synthase beta chain)	152
644918557	369	59.8	1	204	1	203	3.0e-79	289	COG0108	3,4-dihydroxy-2-butanone 4-phosphate synthase	203
644918558	219	51.49	1	201	1	199	2.0e-67	249	COG0307	Riboflavin synthase alpha chain	204
644918559	363	45.21	150	361	1	218	1.0e-50	194	COG1985	Pyrimidine reductase, riboflavin biosynthesis	218
644918560	155	60.78	1	153	1	153	4.0e-57	213	COG1327	Transcriptional regulator NrdR, contains Zn-ribbon and ATP-cone domains	156
644918561	348	30.41	32	345	8	294	2.0e-51	196	COG1230	Co/Zn/Cd efflux system component	296
644918562	422	66.02	6	420	5	413	0.0e+00	667	COG0112	Glycine/serine hydroxymethyltransferase	413
644918563	307	21.38	2	304	1	282	2.0e-24	106	COG1307	Fatty acid-binding protein DegV (function unknown)	282
644918564	554	46.2	3	533	1	526	0.0e+00	557	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
644918568	251	25.78	1	249	2	257	4.0e-36	144	COG1192	Cellulose biosynthesis protein BcsQ	259
644918569	509	27.24	227	479	23	275	4.0e-22	100	COG5607	CHAD domain (function unknown)	283
644918571	141	30.83	15	134	3	122	2.0e-10	58.4	COG1846	DNA-binding transcriptional regulator, MarR family	126
644918572	353	35.67	16	353	13	351	2.0e-64	239	COG1566	Multidrug resistance efflux pump	352
644918573	510	20.48	42	416	36	351	6.0e-17	82.6	COG2814	Predicted arabinose efflux permease, MFS family	394
644918574	455	60.88	1	455	1	453	0.0e+00	651	COG1066	Predicted ATP-dependent serine protease	456
644918582	2564	18	1635	2251	15	556	1.0e-19	94.4	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
644918587	580	22.05	97	348	9	258	6.0e-09	56.5	COG3299	Uncharacterized phage protein gp47/JayE	353
644918592	257	33.04	2	226	1	202	6.0e-34	137	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
644918594	176	19.11	10	160	1	132	1.0e-05	43.3	COG0848	Biopolymer transport protein ExbD	137
644918596	245	29.56	28	229	12	211	9.0e-22	97.4	COG0811	Biopolymer transport protein ExbB/TolQ	216
644918602	1064	33.33	62	463	1	374	2.0e-70	261	COG1472	Periplasmic beta-glucosidase and related glycosidases	397
644918605	458	25.63	1	458	3	417	1.0e-41	164	COG4102	Uncharacterized conserved protein, DUF1501 family	418
644918606	173	19.54	1	173	8	175	5.0e-08	51.2	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
644918610	203	33.66	1	202	3	207	4.0e-27	114	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
644918611	243	23.68	49	220	24	212	8.0e-11	61	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
644918612	206	35.1	1	205	1	208	3.0e-30	124	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
644918614	207	33.65	1	207	1	208	2.0e-25	108	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
644918615	357	23.53	89	282	15	206	2.0e-13	70.7	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
644918616	654	23.26	21	651	1	617	6.0e-61	229	COG1506	Dipeptidyl aminopeptidase/acylaminoacyl peptidase	620
644918618	151	35.87	22	113	1	92	5.0e-18	83.7	COG3326	Uncharacterized membrane protein YsdA, DUF1294 family	94
644918622	818	15.94	8	817	25	768	2.0e-33	137	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
644918624	171	37.28	2	167	1	168	7.0e-32	130	COG0703	Shikimate kinase	172
644918625	94	34.41	1	91	1	93	4.0e-10	56.2	COG0633	Ferredoxin	102
644918626	115	27.52	1	109	1	90	2.0e-06	44.3	COG0633	Ferredoxin	102
644918627	122	22.43	9	115	6	104	1.0e-06	45.3	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
644918630	178	21.55	1	176	1	150	2.0e-06	45.2	COG1225	Peroxiredoxin	157
644918632	159	30.57	8	159	13	169	5.0e-15	73.9	COG2318	Uncharacterized damage-inducible protein DinB (forms a four-helix bundle)	172
644918633	207	25.88	11	174	3	172	2.0e-15	75.9	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
644918636	69	61.19	4	69	1	67	2.0e-21	94.4	COG1278	Cold shock protein, CspA family	67
644918637	461	19.33	1	378	38	391	1.0e-29	124	COG1524	Predicted pyrophosphatase or phosphodiesterase, AlkP superfamily	450
644918638	294	41.86	1	258	1	254	1.0e-82	300	COG1099	Predicted metal-dependent hydrolase, TIM-barrel fold	254
644918642	405	34.6	25	390	12	357	7.0e-74	271	COG0337	3-dehydroquinate synthetase	360
644918647	1849	20.88	697	1069	37	399	3.0e-27	118	COG2133	Glucose/arabinose dehydrogenase, beta-propeller fold	399
644918647	1849	34.73	441	688	23	276	5.0e-35	144	COG3386	Sugar lactone lactonase YvrE	307
644918649	173	28.12	10	164	12	166	3.0e-10	58.1	COG1495	Disulfide bond formation protein DsbB	170
644918650	406	28.5	28	402	7	383	2.0e-35	143	COG2311	Uncharacterized membrane protein YeiB	394
644918651	432	53.61	3	430	1	421	0.0e+00	531	COG0141	Histidinol dehydrogenase	425
644918652	213	46.3	4	210	3	216	7.0e-53	200	COG0040	ATP phosphoribosyltransferase	290
644918653	420	64.52	1	420	1	420	0.0e+00	620	COG0766	UDP-N-acetylglucosamine enolpyruvyl transferase	421
644918654	80	47.5	1	80	1	79	2.0e-17	80.3	COG5007	Acid stress-induced BolA-like protein IbaG/YrbA, predicted regulator of iron metabolism	80
644918655	222	24.02	18	219	6	197	7.0e-19	87.6	COG2854	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic MlaC component	202
644918656	331	40.55	1	328	1	319	7.0e-47	181	COG0530	Ca2+/Na+ antiporter	320
644918657	322	57.71	6	205	1	201	3.0e-66	245	COG0794	D-arabinose 5-phosphate isomerase GutQ	202
644918658	184	53.89	12	178	4	170	2.0e-58	218	COG1778	 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsC and related HAD superfamily phosphatases	170
644918659	210	23.38	3	202	2	184	2.0e-20	92.7	COG3117	Lipopolysaccharide export system protein LptC	188
644918660	194	33.72	16	185	9	173	1.0e-26	113	COG1934	Lipopolysaccharide export system protein LptA	173
644918661	241	66.94	1	241	2	243	6.0e-109	386	COG1137	ABC-type lipopolysaccharide export system, ATPase component	243
644918662	511	44.53	1	511	1	444	0.0e+00	474	COG1508	DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog	444
644918664	150	36.3	2	145	1	145	4.0e-24	103	COG1762	Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type)	152
644918665	292	46.83	1	283	1	283	7.0e-93	333	COG1660	RNase adaptor protein for sRNA GlmZ degradation, contains a P-loop ATPase domain	286
644918666	89	54.55	1	88	1	88	6.0e-22	95.6	COG1925	Phosphotransferase system, HPr and related phosphotransfer proteins	88
644918667	454	35.83	15	454	8	448	3.0e-106	378	COG2239	Mg/Co/Ni transporter MgtE (contains CBS domain)	451
644918668	178	39.88	8	176	15	187	8.0e-37	146	COG3028	Ribosomal 50S subunit-associated protein YjgA (function unknown), DUF615 family	187
644918669	302	29.74	3	300	1	263	2.0e-48	186	COG0388	Predicted amidohydrolase	274
644918670	1600	22.06	1	1010	1	991	2.0e-72	268	COG3164	Uncharacterized conserved protein YhdP, contains DUF3971 and AsmA2 domains	1271
644918671	493	46.76	2	493	1	483	0.0e+00	467	COG1530	Ribonuclease G or E	487
644918672	197	53.72	7	192	5	192	1.0e-58	218	COG0424	Predicted house-cleaning NTP pyrophosphatase, Maf/HAM1 superfamily	193
644918673	163	27.52	10	157	9	157	2.0e-11	62.1	COG2891	Cell shape-determining protein MreD	167
644918674	271	33.96	2	265	12	276	4.0e-50	191	COG1792	Cell shape-determining protein MreC	284
644918675	343	66.57	5	337	1	335	0.0e+00	466	COG1077	Actin-like ATPase involved in cell morphogenesis	342
644918676	93	42.22	4	93	6	95	1.0e-18	84.5	COG0721	Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit	96
644918677	484	51.32	1	480	4	474	0.0e+00	510	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
644918678	481	56.11	1	481	4	482	0.0e+00	687	COG0064	Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit	483
644918680	257	38.4	6	252	3	243	3.0e-42	165	COG2981	Uncharacterized protein involved in cysteine biosynthesis	250
644918681	426	44.89	27	422	15	407	8.0e-110	390	COG0513	Superfamily II DNA and RNA helicase	513
644918682	818	16.84	1	818	15	768	4.0e-36	146	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
644918683	249	43.87	1	247	3	254	4.0e-60	224	COG0476	Molybdopterin or thiamine biosynthesis adenylyltransferase	254
644918684	277	47.01	12	277	12	278	2.0e-68	252	COG2890	Methylase of polypeptide chain release factors	280
644918685	360	67.4	1	360	1	362	0.0e+00	555	COG0216	Protein chain release factor A	363
644918686	415	48.67	1	415	1	412	9.0e-125	440	COG0373	Glutamyl-tRNA reductase	414
644918689	191	27.09	1	189	4	206	1.0e-26	112	COG3017	Outer membrane lipoprotein LolB, involved in outer membrane biogenesis	206
644918691	315	58.15	4	314	3	313	2.0e-119	422	COG0462	Phosphoribosylpyrophosphate synthetase	314
644918692	209	51.61	6	98	2	93	5.0e-24	104	COG1825	Ribosomal protein L25 (general stress protein Ctc)	93
644918693	193	53.76	7	192	4	188	6.0e-67	246	COG0193	Peptidyl-tRNA hydrolase	190
644918694	363	59.95	1	363	1	372	0.0e+00	504	COG0012	Ribosome-binding ATPase YchF, GTP1/OBG family	372
644918699	745	31.74	350	743	19	408	7.0e-52	199	COG0840	Methyl-accepting chemotaxis protein	408
644918704	370	20.98	7	352	1	383	5.0e-16	79.3	COG3182	Uncharacterized iron-regulated membrane protein	442
644918705	705	15.03	11	705	31	768	4.0e-32	133	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
644918706	166	31.03	9	151	2	145	2.0e-21	95	COG3837	Uncharacterized conserved protein, cupin superfamily	161
644918707	226	30.92	13	216	13	219	2.0e-14	73	COG3619	Uncharacterized membrane protein YoaK, UPF0700 family	226
644918709	425	21.39	27	417	77	456	7.0e-49	188	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
644918712	251	24.81	4	249	14	278	4.0e-18	85.5	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
644918713	103	54.37	1	103	7	109	1.0e-31	127	COG4517	Uncharacterized protein	109
644918714	451	51.14	7	445	2	436	0.0e+00	560	COG0621	tRNA A37 methylthiotransferase MiaB	437
644918715	327	52.52	9	321	15	332	3.0e-107	381	COG1702	Phosphate starvation-inducible protein PhoH, predicted ATPase	348
644918716	155	40.13	3	153	1	150	3.0e-35	141	COG0319	ssRNA-specific RNase YbeY, 16S rRNA maturation enzyme	153
644918717	285	53.71	1	282	1	281	1.0e-99	356	COG4535	Mg2+ and Co2+ transporter CorC, contains CBS pair and CorC-HlyC domains	293
644918718	519	34.36	7	514	4	511	8.0e-89	321	COG0815	Apolipoprotein N-acyltransferase	518
644918722	122	24.35	7	121	7	121	6.0e-17	79.5	COG3682	Predicted transcriptional regulator	123
644918724	244	36.19	28	235	1	204	6.0e-41	160	COG0545	FKBP-type peptidyl-prolyl cis-trans isomerase	205
644918725	834	55.81	16	833	1	814	0.0e+00	1080	COG0495	Leucyl-tRNA synthetase	814
644918726	178	27.59	7	175	2	165	4.0e-17	81.1	COG2980	Outer membrane lipoprotein LptE/RlpB (LPS assembly)	178
644918727	349	36.39	14	328	12	326	7.0e-60	224	COG1466	DNA polymerase III, delta subunit	334
644918728	345	12.56	56	265	65	275	9.0e-06	44.6	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
644918729	592	53.43	92	586	1	496	0.0e+00	577	COG5265	ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components	497
644918732	235	28.45	4	235	1	216	2.0e-25	109	COG1451	Predicted metal-dependent hydrolase	223
644918733	134	45.24	8	133	12	135	1.0e-36	145	COG0432	Thiamin phosphate synthase YjbQ, UPF0047 family	137
644918734	609	35.8	38	604	15	567	3.0e-115	409	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
644918735	294	30.21	3	286	1	284	7.0e-31	128	COG0583	DNA-binding transcriptional regulator, LysR family	297
644918736	258	29.74	1	255	2	266	2.0e-48	186	COG1018	Ferredoxin-NADP reductase	266
644918738	233	36.12	1	216	4	230	2.0e-46	179	COG0565	tRNA C32,U32 (ribose-2'-O)-methylase TrmJ or a related methyltransferase	242
644918741	470	29.35	24	468	2	454	7.0e-75	274	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
644918742	324	22.49	12	299	2	287	7.0e-08	51.8	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
644918743	152	17.83	6	134	8	120	1.0e-07	49	COG1310	Proteasome lid subunit RPN8/RPN11, contains Jab1/MPN domain metalloenzyme (JAMM) motif	134
644918744	476	49.8	95	342	2	254	6.0e-72	265	COG0476	Molybdopterin or thiamine biosynthesis adenylyltransferase	254
644918745	306	43.71	2	301	1	298	1.0e-87	316	COG0031	Cysteine synthase	300
644918746	338	41.21	48	212	7	162	5.0e-40	158	COG1045	Serine acetyltransferase	194
644918747	242	39.41	8	239	2	232	3.0e-55	208	COG2872	Ser-tRNA(Ala) deacylase AlaX (editing enzyme)	241
644918748	1080	26.2	31	1035	18	961	5.0e-113	403	COG0610	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases ...	962
644918749	462	31.6	46	310	17	277	2.0e-45	177	COG0758	Predicted Rossmann fold nucleotide-binding protein DprA/Smf involved in DNA uptake	350
644918750	699	31.18	2	614	1	567	2.0e-101	363	COG0514	Superfamily II DNA helicase RecQ	590
644918751	401	20.81	106	395	96	385	2.0e-20	94	COG0732	Restriction endonuclease S subunit	391
644918752	716	25.93	10	433	7	415	2.0e-52	201	COG0286	Type I restriction-modification system, DNA methylase subunit	489
644918758	628	46.77	1	626	3	631	0.0e+00	830	COG0187	DNA gyrase/topoisomerase IV, subunit B	635
644918759	193	40	4	193	2	189	3.0e-47	181	COG3150	Predicted esterase YcpF, UPF0227 family	191
644918760	261	29.24	4	261	1	270	2.0e-27	116	COG1409	3',5'-cyclic AMP phosphodiesterase CpdA	301
644918761	146	32.61	4	136	11	145	2.0e-23	101	COG3151	Uncharacterized protein YqiB, DUF1249 family	147
644918763	639	67.03	136	594	1	432	0.0e+00	761	COG0422	Thiamine biosynthesis protein ThiC	432
644918764	274	48.3	3	266	1	261	6.0e-73	267	COG0351	Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase	263
644918765	458	28.54	16	446	35	455	2.0e-50	193	COG1538	Outer membrane protein TolC	457
644918766	773	61.13	1	770	7	779	0.0e+00	974	COG2183	Transcriptional accessory protein Tex/SPT6	780
644918767	146	27.03	24	134	12	122	2.0e-08	51.5	COG1846	DNA-binding transcriptional regulator, MarR family	126
644918774	175	29.8	33	169	6	155	9.0e-15	73.3	COG1225	Peroxiredoxin	157
644918778	619	40.53	2	577	10	613	8.0e-115	408	COG1297	Uncharacterized membrane protein, oligopeptide transporter (OPT) family	624
644918779	167	36.62	14	152	20	161	6.0e-23	100	COG3236	Predicted NAD-dependent protein-ADP-ribosyltransferase YbiA, DUF1768 family	162
644918780	199	42.76	42	192	3	148	1.0e-35	143	COG3012	Uncharacterized conserved protein YchJ, contains N- and C-terminal SEC-C domains	151
644918781	181	29.82	8	171	2	172	3.0e-24	104	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
644918782	689	28.89	292	680	1	399	4.0e-35	143	COG2304	Secreted protein containing bacterial Ig-like domain and vWFA domain	399
644918785	260	36.23	1	259	1	257	2.0e-49	189	COG2992	Uncharacterized FlgJ-related protein	262
644918787	748	44.4	12	747	9	745	0.0e+00	767	COG0188	DNA gyrase/topoisomerase IV, subunit A	804
644918788	239	24.56	39	204	12	182	2.0e-16	79.2	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
644918791	215	38.25	6	215	16	232	9.0e-33	133	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
644918792	203	25.96	1	198	1	199	9.0e-16	76.9	COG1776	Chemotaxis protein CheY-P-specific phosphatase CheC	203
644918794	498	29.48	90	496	5	406	2.0e-40	160	COG0840	Methyl-accepting chemotaxis protein	408
644918795	988	43.92	14	976	10	953	0.0e+00	867	COG1391	Glutamine synthetase adenylyltransferase	963
644918796	309	43	7	296	1	283	2.0e-73	269	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
644918797	589	36.71	10	589	1	567	6.0e-120	425	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
644918798	423	45.18	2	423	1	419	7.0e-119	420	COG1519	3-deoxy-D-manno-octulosonic-acid transferase	419
644918799	399	23.71	4	364	1	357	7.0e-18	85.2	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
644918800	1057	22.75	15	1034	1	1009	0.0e+00	515	COG0841	Multidrug efflux pump subunit AcrB	1009
644918802	396	25.09	130	395	28	298	1.0e-26	114	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
644918803	391	54.84	1	390	2	395	0.0e+00	470	COG0126	3-phosphoglycerate kinase	395
644918804	667	63.02	1	666	3	663	0.0e+00	1039	COG0021	Transketolase	663
644918805	210	20.61	13	177	6	169	5.0e-09	54.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
644918807	443	25.15	142	443	25	313	6.0e-27	115	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
644918808	317	38.38	13	309	22	314	3.0e-59	222	COG4301	Uncharacterized conserved protein, contains predicted SAM-dependent methyltransferase domain	321
644918810	384	68.73	1	384	1	386	0.0e+00	660	COG0192	S-adenosylmethionine synthetase	388
644918811	462	52.02	11	454	4	420	0.0e+00	572	COG0499	S-adenosylhomocysteine hydrolase	420
644918812	282	38.52	3	281	10	290	4.0e-66	244	COG0685	5,10-methylenetetrahydrofolate reductase	291
644918813	241	43.32	1	240	1	246	4.0e-65	241	COG1385	16S rRNA U1498 N3-methylase RsmE	246
644918817	265	35.29	18	254	17	248	1.0e-60	226	COG1180	Pyruvate-formate lyase-activating enzyme	260
644918820	340	39.83	1	340	1	341	3.0e-99	355	COG2008	Threonine aldolase	342
644918822	456	41.09	5	454	2	447	2.0e-99	356	COG1115	Na+/alanine symporter	452
644918827	163	31.93	21	134	1	115	6.0e-16	76.9	COG5628	Predicted acetyltransferase	143
644918828	415	23.33	7	376	3	382	7.0e-27	115	COG1680	CubicO group peptidase, beta-lactamase class C family	390
644918829	573	46.03	163	572	23	443	4.0e-81	295	COG5297	Cellulase/cellobiase CelA1	544
644918833	153	32.62	10	139	12	152	3.0e-16	77.7	COG0590	tRNA(Arg) A34 adenosine deaminase TadA	152
644918837	454	41.23	1	453	15	467	2.0e-109	390	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
644918838	416	29.97	6	387	2	384	1.0e-70	260	COG0006	Xaa-Pro aminopeptidase	384
644918839	415	35.1	1	410	19	446	2.0e-91	329	COG0160	4-aminobutyrate aminotransferase or related aminotransferase	447
644918840	403	40.11	31	386	16	374	6.0e-98	351	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
644918845	607	67.55	1	604	1	603	0.0e+00	993	COG1217	Predicted membrane GTPase involved in stress response	603
644918846	348	47.35	5	321	2	300	4.0e-96	345	COG0031	Cysteine synthase	300
644918847	413	24.72	70	396	60	411	6.0e-19	89.1	COG1055	Na+/H+ antiporter NhaD or related arsenite permease	424
644918852	599	30.53	7	581	1	505	1.0e-95	344	COG3540	Phosphodiesterase/alkaline phosphatase D	522
644918853	302	28.71	4	300	3	296	1.0e-35	143	COG0583	DNA-binding transcriptional regulator, LysR family	297
644918854	253	37.89	1	251	2	250	1.0e-39	156	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
644918855	308	37.22	1	306	1	293	2.0e-70	259	COG1131	ABC-type multidrug transport system, ATPase component	293
644918858	695	32.71	11	695	33	719	2.0e-111	396	COG4773	Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid	719
644918859	389	20.59	1	383	5	388	3.0e-31	129	COG3182	Uncharacterized iron-regulated membrane protein	442
644918861	116	34.34	17	114	25	123	5.0e-12	63.1	COG0599	Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family	124
644918862	523	28.44	10	496	21	532	4.0e-50	193	COG4987	ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components	573
644918863	554	33.65	27	522	2	513	5.0e-88	319	COG4988	ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components	559
644918864	39	64.86	1	37	1	37	7.0e-08	48.9	COG4890	Predicted outer membrane lipoprotein	37
644918865	379	45.77	1	374	1	346	8.0e-82	297	COG1294	Cytochrome bd-type quinol oxidase, subunit 2	346
644918867	757	40.29	481	757	67	329	1.0e-43	172	COG0642	Signal transduction histidine kinase	336
644918869	334	29.73	6	326	3	314	8.0e-48	184	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
644918878	198	19.39	1	195	1	194	3.0e-09	55.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
644918879	398	36.75	5	381	2	370	9.0e-30	124	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
644918880	1050	54.46	1	1029	2	1009	0.0e+00	1020	COG0841	Multidrug efflux pump subunit AcrB	1009
644918881	329	24.16	25	314	29	317	6.0e-25	108	COG3528	Uncharacterized protein	330
644918884	648	31.04	1	648	3	699	3.0e-113	402	COG4771	Outer membrane receptor for ferrienterochelin and colicins	699
644918887	550	19.8	4	383	2	386	2.0e-23	103	COG3182	Uncharacterized iron-regulated membrane protein	442
644918888	394	36.73	3	384	28	419	4.0e-97	348	COG1169	Isochorismate synthase EntC	423
644918889	538	57.33	7	532	2	533	0.0e+00	720	COG1021	Non-ribosomal peptide synthetase component E (peptide arylation enzyme)	542
644918890	292	57.14	1	210	1	209	2.0e-78	285	COG1535	Isochorismate hydrolase	218
644918891	255	37.55	8	252	1	251	2.0e-44	172	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
644918892	389	31.32	34	377	33	369	3.0e-28	119	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
644918893	1047	49.81	1	1026	1	1009	0.0e+00	925	COG0841	Multidrug efflux pump subunit AcrB	1009
644918894	445	26.38	121	424	24	292	3.0e-32	133	COG2382	Enterochelin esterase or related enzyme	299
644918895	85	51.85	10	63	4	57	9.0e-13	65.1	COG3251	Uncharacterized conserved protein YbdZ, MbtH family	71
644918896	417	19.8	34	394	48	431	1.0e-05	44.4	COG2271	Sugar phosphate permease	448
644918897	154	28	1	150	4	148	6.0e-25	106	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
644918898	112	31.31	1	97	12	110	5.0e-10	56.4	COG0640	DNA-binding transcriptional regulator, ArsR family	110
644918902	200	26.42	10	167	7	161	3.0e-13	68.4	COG1238	Uncharacterized membrane protein YqaA, SNARE-associated domain	161
644918906	52	64.15	1	52	4	56	3.0e-08	50.1	COG0401	Uncharacterized membrane protein YqaE, homolog of Blt101, UPF0057 family	56
644918907	431	29.49	6	377	49	438	5.0e-55	208	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
644918913	851	31.73	70	475	1	374	8.0e-74	272	COG1472	Periplasmic beta-glucosidase and related glycosidases	397
644918914	901	15.21	7	901	19	768	1.0e-24	109	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
644918915	256	38.65	4	252	1	237	2.0e-41	162	COG3279	DNA-binding response regulator, LytR/AlgR family	244
644918922	425	19.85	28	412	24	378	5.0e-15	76.1	COG2942	Mannose or cellobiose epimerase, N-acyl-D-glucosamine 2-epimerase family	388
644918923	392	26.28	45	364	1	313	2.0e-34	140	COG2152	Predicted glycosyl hydrolase, GH43/DUF377 family	314
644918924	634	21.94	5	505	3	485	4.0e-33	136	COG0591	Na+/proline symporter	493
644918925	410	26.32	81	394	1	309	1.0e-30	127	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
644918931	373	33.6	244	367	3	122	8.0e-16	78.4	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
644918932	126	36.63	19	118	9	107	4.0e-15	73.8	COG0607	Rhodanese-related sulfurtransferase	110
644918949	209	26.11	34	183	1	157	3.0e-16	78.9	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
644918956	380	28.46	1	376	1	325	9.0e-56	211	COG0270	Site-specific DNA-cytosine methylase	328
644918975	146	46.53	5	146	8	151	3.0e-40	157	COG1513	Cyanate lyase	151
644918976	572	25.9	271	554	1	302	4.0e-32	132	COG0515	Serine/threonine protein kinase	384
644918977	270	30.04	1	267	3	264	2.0e-36	146	COG2116	Formate/nitrite transporter FocA, FNT family	265
644918978	485	38.37	1	485	8	488	0.0e+00	475	COG0397	Uncharacterized conserved protein YdiU, UPF0061 family	488
644918984	184	24.32	2	184	11	195	3.0e-12	65.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
644918987	120	40.21	9	102	9	103	2.0e-19	88.1	COG3695	Alkylated DNA nucleotide flippase Atl1, participates in nucleotide excision repair, Ada-like DNA-binding domain	103
644918989	421	46.35	1	391	1	394	2.0e-121	429	COG0019	Diaminopimelate decarboxylase	394
644918990	276	53.68	3	274	1	270	4.0e-95	341	COG0253	Diaminopimelate epimerase	272
644918991	227	37.67	12	226	4	216	4.0e-43	168	COG3159	Uncharacterized conserved protein YigA, DUF484 family	218
644918993	112	71.43	1	112	1	112	8.0e-41	158	COG0347	Nitrogen regulatory protein PII	112
644918994	427	36.89	9	425	1	408	2.0e-75	276	COG0004	Ammonia channel protein AmtB	409
644918995	112	70.54	1	112	1	112	8.0e-41	158	COG0347	Nitrogen regulatory protein PII	112
644918997	413	47.09	4	408	3	411	2.0e-106	379	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
644918998	160	27.5	1	116	1	120	5.0e-18	83.9	COG1733	DNA-binding transcriptional regulator, HxlR family	120
644919006	231	44.26	1	231	3	237	9.0e-79	286	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
644919007	260	61.73	18	260	4	246	2.0e-101	362	COG4674	ABC-type uncharacterized transport system, ATPase component	249
644919008	388	34.01	17	360	1	309	4.0e-55	208	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
644919009	563	41.92	271	559	6	295	6.0e-68	251	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
644919010	432	31.47	21	388	2	365	1.0e-65	244	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
644919013	204	54.23	4	203	10	202	2.0e-64	238	COG0378	Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase	202
644919014	221	31.56	3	221	5	229	2.0e-35	142	COG0830	Urease accessory protein UreF	229
644919015	154	45.21	8	153	12	155	6.0e-30	123	COG2371	Urease accessory protein UreE	155
644919016	567	79.05	1	567	1	568	0.0e+00	1067	COG0804	Urease alpha subunit	568
644919017	107	60.95	1	105	1	105	4.0e-42	162	COG0832	Urease beta subunit	106
644919018	100	78.79	1	99	1	99	9.0e-44	168	COG0831	Urease gamma subunit	100
644919019	287	37.73	14	285	6	269	3.0e-58	218	COG0829	Urease accessory protein UreH	269
644919020	389	56.92	1	389	1	387	0.0e+00	496	COG0754	Glutathionylspermidine synthase	387
644919021	209	32.37	1	200	2	198	6.0e-24	104	COG5463	Uncharacterized conserved protein YgiB, involved in bioifilm formation, UPF0441/DUF1190 family	198
644919022	138	46.27	5	138	2	133	1.0e-24	105	COG3766	Uncharacterized membrane protein YjfL, UPF0719 family	133
644919027	230	29.02	3	226	4	222	7.0e-16	77.6	COG1842	Phage shock protein A	225
644919028	133	28.78	1	129	5	143	2.0e-12	65	COG3789	Uncharacterized protein YjfI, DUF2170 family	146
644919030	239	23.74	1	231	4	255	2.0e-07	49.5	COG0428	Zinc transporter ZupT	266
644919032	542	25.36	36	536	22	549	4.0e-52	199	COG3507	Beta-xylosidase	549
644919033	352	19.35	120	328	70	279	8.0e-07	48.6	COG1073	Fermentation-respiration switch protein FrsA, has esterase activity, DUF1100 family	299
644919037	380	30.14	36	374	1	309	6.0e-45	175	COG1957	Inosine-uridine nucleoside N-ribohydrolase	311
644919038	432	22.09	10	421	2	409	2.0e-38	154	COG2072	Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD	443
644919040	338	32.51	17	335	3	318	2.0e-52	200	COG2144	Selenophosphate synthetase-related protein	324
644919042	390	21.71	19	367	10	336	3.0e-34	139	COG2516	Biotin synthase-related protein, radical SAM superfamily	339
644919043	349	24.09	3	301	2	274	4.0e-26	112	COG0388	Predicted amidohydrolase	274
644919050	286	23.91	43	266	1	212	3.0e-12	66.1	COG2755	Lysophospholipase L1 or related esterase	216
644919056	1753	19.23	914	1662	11	725	1.0e-08	56.8	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
644919060	85	43.37	2	84	16	95	5.0e-09	52.7	COG2960	Uncharacterized conserved protein YqiC, BMFP domain	103
644919061	512	56.65	15	496	1	489	0.0e+00	608	COG0606	Predicted ATPase with chaperone activity	490
644919065	1140	32.03	602	902	38	335	4.0e-44	174	COG0642	Signal transduction histidine kinase	336
644919066	420	32.79	46	408	1	366	2.0e-62	233	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
644919067	308	37.25	12	307	4	295	4.0e-45	175	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
644919068	380	29.86	16	355	7	314	2.0e-41	163	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
644919069	248	57.26	8	247	5	245	4.0e-90	324	COG4674	ABC-type uncharacterized transport system, ATPase component	249
644919070	229	44.73	1	229	3	237	8.0e-74	270	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
644919071	410	33.6	17	384	6	300	3.0e-64	239	COG2421	Acetamidase/formamidase	305
644919077	702	33.18	286	698	24	427	4.0e-52	200	COG5520	O-Glycosyl hydrolase	433
644919079	1018	34.44	215	481	1	268	9.0e-61	229	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
644919080	623	28.46	376	623	93	336	8.0e-28	119	COG0642	Signal transduction histidine kinase	336
644919082	65	33.9	1	59	3	61	5.0e-07	46.1	COG3237	Uncharacterized conserved protein YjbJ, UPF0337 family	67
644919086	327	27.94	13	320	4	318	2.0e-23	103	COG0392	Uncharacterized membrane protein YbhN, UPF0104 family	322
644919087	439	31.69	11	365	57	422	1.0e-54	207	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
644919088	250	38.82	7	250	11	259	3.0e-45	175	COG3568	Metal-dependent hydrolase, endonuclease/exonuclease/phosphatase family	259
644919090	673	44.95	4	647	3	647	0.0e+00	574	COG0210	Superfamily I DNA or RNA helicase	655
644919091	248	27.17	1	247	7	256	2.0e-28	119	COG0300	Short-chain dehydrogenase	265
644919092	439	20.33	38	433	59	457	4.0e-30	126	COG0277	FAD/FMN-containing dehydrogenase	459
644919093	486	24.1	182	483	1	288	1.0e-29	124	COG0382	4-hydroxybenzoate polyprenyltransferase	289
644919094	317	19.94	4	314	17	320	7.0e-09	55.1	COG0392	Uncharacterized membrane protein YbhN, UPF0104 family	322
644919096	135	40.15	4	135	1	126	5.0e-25	106	COG3245	Cytochrome c5	126
644919100	1059	33.69	222	858	1	638	9.0e-120	425	COG1020	Non-ribosomal peptide synthetase component F	642
644919102	367	26.76	1	343	13	360	6.0e-25	108	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
644919103	1244	36.13	7	910	2	904	0.0e+00	620	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
644919106	662	27.5	1	626	1	534	2.0e-90	327	COG0367	Asparagine synthetase B (glutamine-hydrolyzing)	542
644919111	479	22.3	1	478	3	539	3.0e-34	139	COG2303	Choline dehydrogenase or related flavoprotein	542
644919114	458	23.38	1	458	2	455	4.0e-13	69.7	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
644919118	365	21.05	1	365	1	379	8.0e-29	121	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
644919120	369	40.44	15	237	12	233	6.0e-51	195	COG1922	UDP-N-acetyl-D-mannosaminuronic acid transferase, WecB/TagA/CpsF family	253
644919121	409	32.23	127	408	88	381	3.0e-34	139	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
644919124	632	60.29	19	436	1	418	0.0e+00	627	COG2895	Sulfate adenylyltransferase subunit 1, EFTu-like GTPase family	431
644919125	304	37.22	4	304	12	261	8.0e-58	217	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
644919126	273	46.55	1	270	1	269	2.0e-70	259	COG1218	3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase	276
644919128	318	27.97	9	288	7	280	3.0e-36	146	COG1216	Glycosyltransferase, GT2 family	305
644919129	527	19.49	5	451	4	458	9.0e-22	98.6	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
644919132	473	45.85	247	473	5	226	4.0e-65	242	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
644919133	356	58.76	3	356	1	329	0.0e+00	520	COG1088	dTDP-D-glucose 4,6-dehydratase	340
644919134	288	46.02	1	286	1	281	8.0e-76	277	COG1091	dTDP-4-dehydrorhamnose reductase	281
644919135	182	62.15	1	177	1	173	1.0e-62	232	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase or related enzyme	173
644919136	332	55.71	43	330	1	286	6.0e-112	397	COG1209	dTDP-glucose pyrophosphorylase	286
644919141	366	45.85	14	337	4	320	7.0e-102	364	COG0276	Protoheme ferro-lyase (ferrochelatase)	320
644919142	277	36.69	1	276	7	312	1.0e-52	200	COG0627	S-formylglutathione hydrolase FrmB	316
644919144	293	28.42	11	292	14	297	1.0e-34	140	COG3735	Uncharacterized conserved protein YbaP, TraB family	299
644919145	393	23.92	15	384	1	431	1.0e-41	163	COG2265	tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family	432
644919151	494	56.46	42	493	2	458	0.0e+00	613	COG1207	Bifunctional protein GlmU, N-acetylglucosamine-1-phosphate-uridyltransferase/glucosamine-1-phosphate-acetyltransferase	460
644919153	677	17.21	43	676	83	767	4.0e-19	90.4	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
644919154	423	23.53	1	343	3	336	2.0e-23	103	COG1252	NADH dehydrogenase, FAD-containing subunit	405
644919155	577	43.09	393	572	2	181	3.0e-43	170	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
644919156	255	41.67	5	255	2	252	7.0e-58	217	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
644919157	610	54.08	1	610	1	597	0.0e+00	799	COG0449	Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains	597
644919162	212	22.22	7	202	7	204	8.0e-14	70.5	COG5340	Transcriptional regulator, predicted component of viral defense system	269
644919164	360	31.82	49	266	43	252	3.0e-33	136	COG1604	CRISPR/Cas system CMR subunit Cmr6, Cas7 group, RAMP superfamily	257
644919165	133	20.45	8	121	2	133	1.0e-05	42.4	COG3337	CRISPR/Cas system CMR-associated protein Cmr5, small subunit	134
644919166	298	32.21	8	288	2	291	3.0e-51	195	COG1336	CRISPR/Cas system CMR subunit Cmr4, Cas7 group, RAMP superfamily	298
644919169	473	23.76	31	438	14	382	3.0e-37	149	COG1367	CRISPR/Cas system CMR-associated protein Cmr1, group 7 of RAMP superfamily	393
644919175	177	32.78	1	173	2	181	6.0e-23	100	COG3038	Cytochrome b561	181
644919177	183	33.96	6	164	18	176	2.0e-25	108	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
644919178	255	23.79	1	240	1	240	5.0e-09	55.1	COG5662	Transmembrane transcriptional regulator (anti-sigma factor RsiW)	256
644919182	701	34.48	1	691	6	710	0.0e+00	537	COG0643	Chemotaxis protein histidine kinase CheA	716
644919183	683	31.36	264	627	4	408	5.0e-30	126	COG0840	Methyl-accepting chemotaxis protein	408
644919184	184	30.77	1	169	1	165	8.0e-30	123	COG0835	Chemotaxis signal transduction protein	165
644919185	283	37.73	15	283	1	266	6.0e-59	220	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
644919186	350	46.4	1	346	1	340	1.0e-96	346	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
644919187	175	29.94	4	157	6	155	5.0e-22	97.6	COG1871	Chemotaxis receptor (MCP) glutamine deamidase CheD	164
644919189	1059	22.8	6	1017	1	1006	9.0e-122	431	COG0841	Multidrug efflux pump subunit AcrB	1009
644919190	388	24.28	30	364	17	352	4.0e-16	79.4	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
644919191	310	19.56	88	310	37	258	2.0e-11	63.8	COG3713	Outer membrane scaffolding protein for murein synthesis, MipA/OmpV family	258
644919192	446	26.06	129	446	1	327	4.0e-29	122	COG0642	Signal transduction histidine kinase	336
644919193	223	39.91	1	222	1	227	6.0e-52	197	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
644919194	398	24.61	1	376	1	365	4.0e-43	169	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
644919197	261	36.86	30	261	4	236	1.0e-51	197	COG3208	Surfactin synthase thioesterase subunit	244
644919198	146	21.43	36	146	31	141	3.0e-14	71.2	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
644919199	2141	26.89	1502	1730	67	298	1.0e-17	87	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
644919199	2141	38.78	27	1084	6	1025	0.0e+00	808	COG3321	Acyl transferase domain in polyketide synthase (PKS) enzymes	1061
644919203	389	28.87	8	377	8	354	4.0e-52	199	COG1858	Cytochrome c peroxidase	364
644919205	288	21.5	2	288	1	303	8.0e-37	147	COG0826	Collagenase-like protease, PrtC family	347
644919206	332	35.8	1	332	7	312	2.0e-71	262	COG0826	Collagenase-like protease, PrtC family	347
644919207	173	44.12	23	158	13	146	2.0e-23	102	COG3154	Predicted lipid carrier protein YhbT, SCP2 domain	168
644919209	418	44.15	4	412	1	402	5.0e-115	408	COG0303	Molybdopterin biosynthesis enzyme	404
644919210	127	27.66	3	126	1	138	4.0e-10	57.1	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
644919211	348	23.78	1	327	7	369	2.0e-27	116	COG1680	CubicO group peptidase, beta-lactamase class C family	390
644919213	1039	38.36	5	1017	2	1008	0.0e+00	826	COG0841	Multidrug efflux pump subunit AcrB	1009
644919214	413	26.83	49	396	9	367	1.0e-26	114	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
644919215	477	33.94	43	459	26	462	4.0e-61	229	COG3934	Endo-1,4-beta-mannosidase	587
644919216	331	42.12	3	328	2	331	5.0e-89	321	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
644919219	490	40.52	1	382	2	379	2.0e-97	349	COG0301	Adenylyl- and sulfurtransferase ThiI, participates in tRNA 4-thiouridine and thiamine biosynthesis	383
644919220	468	49.47	3	468	4	443	0.0e+00	528	COG0174	Glutamine synthetase	443
644919222	354	42.17	7	354	10	359	4.0e-97	348	COG3852	Signal transduction histidine kinase, nitrogen specific	363
644919223	471	49.26	1	469	1	460	0.0e+00	537	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
644919224	167	52.53	10	167	1	155	3.0e-41	160	COG1952	Preprotein translocase subunit SecB	157
644919225	132	37.25	33	132	7	108	2.0e-14	71.1	COG0607	Rhodanese-related sulfurtransferase	110
644919226	248	62.61	1	230	1	230	5.0e-103	367	COG0588	Phosphoglycerate mutase (BPG-dependent)	230
644919227	392	29.63	19	390	16	419	2.0e-58	219	COG4942	Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB	420
644919228	455	45.04	3	368	3	367	8.0e-96	344	COG0793	C-terminal processing protease CtpA/Prc, contains a PDZ domain	406
644919229	275	44.75	41	258	26	244	5.0e-55	208	COG2861	Uncharacterized conserved protein YibQ, putative polysaccharide deacetylase 2 family	250
644919231	154	26.39	7	148	13	156	8.0e-06	43.4	COG3678	Periplasmic protein refolding chaperone Spy/CpxP family	160
644919232	231	43.61	5	227	1	225	1.0e-55	209	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
644919233	434	27.45	135	434	31	329	4.0e-39	156	COG0642	Signal transduction histidine kinase	336
644919240	315	25.5	12	299	3	291	3.0e-12	66.1	COG3547	Transposase	303
644919248	499	36.36	36	153	34	151	6.0e-09	55.9	COG3666	Transposase	161
644919249	268	29.79	33	267	12	228	1.0e-10	60.4	COG2801	Transposase InsO and inactivated derivatives	232
644919251	315	26.87	12	302	3	283	1.0e-13	70.7	COG3547	Transposase	303
644919260	188	25.14	13	180	1	175	3.0e-17	81.9	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
644919269	500	37.19	36	153	34	151	5.0e-10	59.7	COG3666	Transposase	161
644919282	108	42.06	1	107	1	107	1.0e-23	101	COG4551	Predicted protein tyrosine phosphatase	109
644919284	161	28.71	24	124	13	108	2.0e-06	45.7	COG0526	Thiol-disulfide isomerase or thioredoxin	127
644919286	178	34.13	5	170	12	176	3.0e-31	128	COG2229	Signal recognition particle receptor subunit beta, a GTPase	187
644919287	128	27.78	17	106	10	96	1.0e-05	42.1	COG2018	Predicted regulator of Ras-like GTPase activity, Roadblock/LC7/MglB family	119
644919290	530	23.31	6	491	1	476	7.0e-43	168	COG0591	Na+/proline symporter	493
644919292	436	22.25	42	436	1	356	8.0e-39	155	COG3405	Endo-1,4-beta-D-glucanase Y	360
644919295	391	21.58	31	391	6	380	1.0e-22	101	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
644919297	443	22.4	1	433	8	430	1.0e-13	71.7	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
644919299	895	27.32	175	372	36	239	5.0e-19	90.6	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
644919304	319	23.75	16	303	3	306	2.0e-11	63.3	COG1560	Lauroyl/myristoyl acyltransferase	308
644919305	557	42.8	325	557	5	226	3.0e-61	230	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
644919308	485	32.23	1	485	12	523	4.0e-99	355	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
644919310	290	24.82	16	274	31	301	7.0e-12	64.9	COG1560	Lauroyl/myristoyl acyltransferase	308
644919313	206	30.77	35	202	8	167	4.0e-17	81.5	COG3161	4-hydroxybenzoate synthetase (chorismate-pyruvate lyase)	174
644919314	88	46.51	1	86	2	87	2.0e-13	67.5	COG4095	Uncharacterized conserved protein, contains PQ loop repeat	89
644919315	353	27.21	17	278	27	294	5.0e-39	155	COG2008	Threonine aldolase	342
644919318	155	50.32	1	155	1	154	5.0e-44	170	COG2193	Bacterioferritin (cytochrome b1)	157
644919321	208	33.99	2	204	1	202	2.0e-43	169	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
644919322	528	22.22	1	162	15	163	2.0e-09	58	COG0835	Chemotaxis signal transduction protein	165
644919327	76	37.84	2	74	4	66	4.0e-08	50	COG3529	Predicted nucleic-acid-binding protein, contains Zn-ribbon domain	66
644919328	523	28.57	98	365	6	282	5.0e-27	116	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
644919329	684	55.99	4	684	7	683	0.0e+00	855	COG0339	Zn-dependent oligopeptidase	683
644919330	180	45.2	4	180	1	170	6.0e-52	196	COG0663	Carbonic anhydrase or acetyltransferase, isoleucine patch superfamily	176
644919331	281	34.29	1	279	7	282	1.0e-64	239	COG2897	3-mercaptopyruvate sulfurtransferase SseA, contains two rhodanese domains	285
644919332	491	23.53	237	486	17	236	4.0e-30	126	COG2356	Endonuclease I	237
644919333	170	30.63	2	106	1	111	1.0e-13	69.4	COG0789	DNA-binding transcriptional regulator, MerR family	124
644919334	189	37.7	15	189	21	200	7.0e-35	140	COG4430	Uncharacterized conserved protein YdeI, YjbR/CyaY-like superfamily, DUF1801 family	200
644919335	224	19.64	13	221	26	249	3.0e-17	82.3	COG3751	Proline 4-hydroxylase (includes Rps23 Pro-64 3,4-dihydroxylase Tpa1), contains SM-20 domain	252
644919336	156	55.48	1	155	1	154	1.0e-40	158	COG2606	Cys-tRNA(Pro) deacylase, prolyl-tRNA editing enzyme YbaK/EbsC	155
644919344	400	42.12	1	385	8	387	2.0e-108	385	COG3146	Predicted N-acyltransferase	387
644919345	439	29.95	75	425	87	447	9.0e-45	174	COG5002	Signal transduction histidine kinase	459
644919346	235	46.09	4	229	1	228	3.0e-62	231	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
644919347	296	40.97	7	293	1	288	4.0e-58	218	COG0382	4-hydroxybenzoate polyprenyltransferase	289
644919348	93	45.98	1	87	2	88	1.0e-22	97.9	COG0776	Bacterial nucleoid DNA-binding protein	94
644919349	429	38.46	2	429	4	408	3.0e-80	292	COG1301	Na+/H+-dicarboxylate symporter	415
644919350	228	25.23	9	227	1	206	5.0e-26	111	COG2928	Uncharacterized membrane protein	222
644919352	460	29.27	171	416	5	245	5.0e-45	175	COG1639	HD-like signal output (HDOD) domain, no enzymatic activity	289
644919353	677	49.78	2	670	19	677	0.0e+00	790	COG1200	RecG-like helicase	677
644919354	366	30.23	37	366	2	340	2.0e-46	180	COG0673	Predicted dehydrogenase	342
644919358	256	57.81	1	256	1	252	4.0e-80	290	COG3022	Cytoplasmic iron level regulating protein YaaA, DUF328/UPF0246 family	253
644919360	429	28.31	8	419	10	446	1.0e-40	161	COG4783	Putative Zn-dependent protease, contains TPR repeats	484
644919363	326	21.45	21	295	1	314	2.0e-15	76.9	COG3203	Outer membrane protein (porin)	354
644919364	239	38.82	2	238	1	237	1.0e-39	156	COG0704	Phosphate uptake regulator	240
644919365	300	65.2	51	300	6	253	9.0e-125	439	COG1117	ABC-type phosphate transport system, ATPase component	253
644919366	430	41.41	177	430	38	292	3.0e-65	243	COG0581	ABC-type phosphate transport system, permease component	292
644919367	494	41.29	186	493	12	310	2.0e-70	260	COG0573	ABC-type phosphate transport system, permease component	310
644919368	347	25.07	4	329	22	316	2.0e-35	143	COG0226	ABC-type phosphate transport system, periplasmic component	318
644919369	173	35.4	7	167	2	161	9.0e-29	119	COG4665	TRAP-type mannitol/chloroaromatic compound transport system, small permease component	182
644919370	456	47.82	4	454	6	445	2.0e-109	389	COG4664	TRAP-type mannitol/chloroaromatic compound transport system, large permease component	447
644919371	131	44.62	1	130	1	130	2.0e-38	151	COG1607	Acyl-CoA hydrolase	157
644919372	383	42.82	32	379	11	357	3.0e-106	378	COG4663	TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component	363
644919373	236	42.2	1	218	1	217	6.0e-46	177	COG3148	Uncharacterized conserved protein YfiP, DTW domain	231
644919376	879	21.75	132	696	68	689	3.0e-20	94.4	COG0553	Superfamily II DNA or RNA helicase, SNF2 family	866
644919377	88	55.56	1	81	1	80	1.0e-23	101	COG2827	Predicted endonuclease, GIY-YIG superfamily	95
644919378	298	47.42	1	291	1	290	3.0e-69	255	COG2962	Uncharacterized membrane protein RarD, contains two EamA domains	293
644919380	431	37.64	252	426	1	178	3.0e-33	136	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
644919383	210	36.71	1	203	1	207	8.0e-43	167	COG2808	Predicted FMN-binding regulatory protein PaiB	209
644919387	403	22.25	8	394	8	390	1.0e-08	54.8	COG2814	Predicted arabinose efflux permease, MFS family	394
644919397	485	33.33	154	481	15	362	1.0e-50	194	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)	364
644919398	736	20.48	1	682	1	640	5.0e-28	120	COG4771	Outer membrane receptor for ferrienterochelin and colicins	699
644919399	312	29.38	142	310	3	174	4.0e-16	79	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
644919400	335	38.2	243	330	37	125	4.0e-12	66	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
644919402	326	34.4	30	277	7	236	3.0e-32	132	COG3220	Uncharacterized conserved protein, UPF0276 family	282
644919407	146	34.09	15	137	3	132	1.0e-14	72.7	COG4968	Tfp pilus assembly protein PilE	139
644919410	303	28.91	4	292	3	289	1.0e-37	150	COG0583	DNA-binding transcriptional regulator, LysR family	297
644919411	330	37.58	2	329	1	326	3.0e-61	229	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
644919413	391	53	1	388	2	400	0.0e+00	486	COG2081	Predicted flavoprotein YhiN	408
644919414	478	34.6	12	477	3	443	1.0e-90	327	COG4452	Inner membrane protein involved in colicin E2 resistance	443
644919415	330	41.46	1	323	1	314	3.0e-79	288	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
644919416	302	51.12	1	301	1	303	2.0e-83	302	COG2354	Uncharacterized membrane protein MutK, may be involved in DNA repair	303
644919419	461	42.12	11	376	3	347	8.0e-71	261	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
644919420	188	29.17	46	188	3	146	6.0e-23	100	COG0071	Molecular chaperone IbpA, HSP20 family	146
644919421	154	37.06	1	138	7	146	1.0e-25	109	COG0071	Molecular chaperone IbpA, HSP20 family	146
644919422	214	49	4	203	2	198	6.0e-63	233	COG0218	GTP-binding protein EngB required for normal cell division	200
644919423	217	40	3	106	2	102	2.0e-17	82.3	COG2863	Cytochrome c553	121
644919425	302	29.14	7	302	2	296	2.0e-31	130	COG0583	DNA-binding transcriptional regulator, LysR family	297
644919426	163	24.79	31	145	9	124	3.0e-07	48.4	COG3607	Predicted lactoylglutathione lyase	133
644919430	179	25.62	15	169	14	166	2.0e-13	68.4	COG2258	Uncharacterized conserved protein YiiM, contains MOSC domain	210
644919432	432	23.92	135	428	19	313	2.0e-27	117	COG0701	Uncharacterized membrane protein YraQ, UPF0718 family	317
644919436	393	32.93	5	319	3	326	2.0e-56	213	COG1858	Cytochrome c peroxidase	364
644919437	728	44.95	8	658	1	655	0.0e+00	596	COG0210	Superfamily I DNA or RNA helicase	655
644919440	255	48.61	5	255	4	245	6.0e-62	230	COG1189	Predicted rRNA methylase YqxC, contains S4 and FtsJ domains	245
644919442	444	56.88	9	443	4	438	0.0e+00	560	COG2115	Xylose isomerase	438
644919443	311	27.56	1	307	9	305	4.0e-36	145	COG2017	Galactose mutarotase or related enzyme	308
644919444	496	32.26	1	493	4	492	1.0e-82	300	COG1070	Sugar (pentulose or hexulose) kinase	502
644919446	357	20.33	1	356	7	353	1.0e-14	74	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
644919447	417	25.48	20	417	1	419	7.0e-32	131	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
644919448	418	24.29	17	418	1	419	7.0e-27	115	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
644919449	226	51.79	1	222	1	224	1.0e-77	282	COG1136	ABC-type lipoprotein export system, ATPase component	226
644919450	576	33.27	42	565	2	529	1.0e-87	317	COG3507	Beta-xylosidase	549
644919451	397	32.35	61	397	23	345	1.0e-62	234	COG3693	Endo-1,4-beta-xylanase, GH35 family	345
644919455	748	22.48	20	746	15	724	4.0e-65	242	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
644919456	157	53.9	1	153	3	156	3.0e-57	213	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
644919457	379	28.77	13	156	1	143	6.0e-17	81.9	COG2703	Hemerythrin	144
644919460	484	34.33	32	484	29	488	1.0e-72	267	COG0168	Trk-type K+ transport system, membrane component	499
644919461	763	58.61	431	761	2	330	3.0e-127	449	COG0620	Methionine synthase II (cobalamin-independent)	330
644919462	304	26.64	14	300	1	284	9.0e-28	117	COG0583	DNA-binding transcriptional regulator, LysR family	297
644919464	898	31.11	8	711	33	764	0.0e+00	469	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
644919465	234	39.67	4	232	2	243	4.0e-41	161	COG1462	Curli biogenesis system outer membrane secretion channel CsgG	252
644919466	125	36.19	12	116	17	117	8.0e-18	82.4	COG4259	Uncharacterized protein	121
644919467	218	40.89	5	205	2	203	3.0e-41	161	COG4380	Uncharacterized protein	216
644919468	211	25.48	2	204	1	203	9.0e-21	93.7	COG0625	Glutathione S-transferase	211
644919469	130	42.45	9	114	3	107	4.0e-24	103	COG1733	DNA-binding transcriptional regulator, HxlR family	120
644919470	442	34.18	9	433	3	423	4.0e-59	222	COG1055	Na+/H+ antiporter NhaD or related arsenite permease	424
644919485	141	52.27	4	134	3	133	1.0e-28	118	COG0355	FoF1-type ATP synthase, epsilon subunit	135
644919486	470	73.47	1	468	1	468	0.0e+00	817	COG0055	FoF1-type ATP synthase, beta subunit	468
644919487	286	55.24	5	286	1	286	3.0e-101	361	COG0224	FoF1-type ATP synthase, gamma subunit	287
644919488	513	65.62	3	513	2	502	0.0e+00	802	COG0056	FoF1-type ATP synthase, alpha subunit	504
644919489	178	41.24	1	176	1	177	5.0e-36	143	COG0712	FoF1-type ATP synthase, delta subunit	178
644919490	156	37.75	6	156	8	158	6.0e-17	80.3	COG0711	FoF1-type ATP synthase, membrane subunit b or b'	161
644919491	82	41.1	4	76	6	78	1.0e-05	41.7	COG0636	FoF1-type ATP synthase, membrane subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K	79
644919492	311	35.2	59	308	24	246	1.0e-39	157	COG0356	FoF1-type ATP synthase, membrane subunit a	246
644919493	121	26.61	2	110	9	117	5.0e-08	50.2	COG3312	FoF1-type ATP synthase assembly protein I	128
644919495	306	40	46	298	2	240	3.0e-35	142	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
644919496	264	42.13	1	252	1	253	3.0e-60	225	COG1192	Cellulose biosynthesis protein BcsQ	259
644919497	211	43.81	4	205	1	210	9.0e-55	206	COG0357	16S rRNA G527 N7-methylase RsmG (former glucose-inhibited division protein B)	215
644919498	493	42.04	262	487	44	269	6.0e-69	255	COG2326	Polyphosphate kinase 2, PPK2 family	270
644919504	249	36	3	249	2	241	1.0e-40	160	COG3279	DNA-binding response regulator, LytR/AlgR family	244
644919505	630	63.78	3	624	1	621	0.0e+00	971	COG0445	tRNA U34 5-carboxymethylaminomethyl modifying enzyme MnmG/GidA	621
644919507	449	50.77	1	449	4	454	0.0e+00	546	COG0486	tRNA U34 5-carboxymethylaminomethyl modifying GTPase MnmE/TrmE	454
644919508	560	46.67	268	558	3	299	3.0e-74	273	COG0706	Membrane protein insertase Oxa1/YidC/SpoIIIJ, required for the localization of integral membrane proteins	314
644919509	136	35.9	9	125	1	117	3.0e-17	81.1	COG0594	RNase P protein component	117
