gene_oid	gene_length	percent_identity	query_start	query_end	subj_start	subj_end	evalue	bit_score	cog_id	cog_name	cog_length
646764595	532	56.59	195	528	78	408	3.0e-118	418	COG0593	Chromosomal replication initiation ATPase DnaA	408
646764596	367	39.62	4	367	3	364	2.0e-79	289	COG0592	DNA polymerase III sliding clamp (beta) subunit, PCNA homolog	364
646764597	823	60.83	10	582	3	559	0.0e+00	868	COG0187	DNA gyrase/topoisomerase IV, subunit B	635
646764598	464	60.18	1	437	1	436	0.0e+00	691	COG4303	Ethanolamine ammonia-lyase, large subunit	453
646764599	263	46.06	5	243	60	294	5.0e-66	244	COG4302	Ethanolamine ammonia-lyase, small subunit	294
646764600	814	42.16	111	814	3	710	0.0e+00	661	COG2217	Cation transport ATPase	713
646764601	143	33.96	1	105	1	106	7.0e-19	86.3	COG0789	DNA-binding transcriptional regulator, MerR family	124
646764603	467	44.17	11	372	31	399	5.0e-108	385	COG0513	Superfamily II DNA and RNA helicase	513
646764604	384	35.6	24	383	23	387	1.0e-85	310	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
646764605	264	28.25	1	264	6	271	2.0e-37	149	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
646764606	288	39.62	183	287	14	119	6.0e-19	88.4	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
646764607	195	32.35	1	195	3	206	4.0e-17	81.5	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
646764609	505	51.38	320	500	2	179	5.0e-43	169	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
646764611	134	34.38	8	134	11	138	1.0e-17	82.4	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
646764613	337	33.74	3	329	1	317	1.0e-64	240	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
646764614	618	63.52	4	616	1	606	0.0e+00	925	COG1274	Phosphoenolpyruvate carboxykinase, GTP-dependent	608
646764615	367	31.21	4	297	3	295	2.0e-40	159	COG0583	DNA-binding transcriptional regulator, LysR family	297
646764616	905	32.38	20	640	1	569	0.0e+00	475	COG0550	DNA topoisomerase IA	570
646764618	409	37.53	10	406	5	350	1.0e-88	320	COG0758	Predicted Rossmann fold nucleotide-binding protein DprA/Smf involved in DNA uptake	350
646764619	167	54.49	1	164	1	167	2.0e-56	211	COG0242	Peptide deformylase	168
646764620	331	47.5	4	323	1	307	2.0e-101	362	COG0223	Methionyl-tRNA formyltransferase	307
646764621	213	39.61	7	213	6	208	2.0e-32	132	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
646764622	285	33.8	8	283	33	301	5.0e-42	164	COG0501	Zn-dependent protease with chaperone function	302
646764623	479	34.9	126	479	3	354	2.0e-72	267	COG0144	16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family	355
646764625	808	34.12	18	770	8	706	0.0e+00	517	COG5000	Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation	712
646764628	270	41.03	34	261	2	212	2.0e-63	235	COG0603	7-cyano-7-deazaguanine synthase (queuosine biosynthesis)	222
646764629	210	37.44	1	210	2	212	5.0e-43	167	COG0602	Organic radical activating enzyme	212
646764630	148	31.03	1	145	2	124	5.0e-21	93.5	COG0720	6-pyruvoyl-tetrahydropterin synthase	127
646764631	260	47.51	1	260	1	255	1.0e-60	226	COG3836	2-keto-3-deoxy-L-rhamnonate aldolase RhmA	255
646764632	244	27.73	9	240	5	241	3.0e-18	85.9	COG0790	TPR repeat	292
646764633	382	42.82	19	382	14	377	8.0e-76	277	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
646764634	791	32.41	2	631	1	595	8.0e-126	444	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
646764635	170	36.31	8	161	4	160	1.0e-20	92.6	COG2891	Cell shape-determining protein MreD	167
646764636	378	32.51	7	288	1	280	4.0e-53	202	COG1792	Cell shape-determining protein MreC	284
646764637	347	67.64	5	345	1	340	0.0e+00	468	COG1077	Actin-like ATPase involved in cell morphogenesis	342
646764638	99	45.45	1	99	1	95	2.0e-19	87.6	COG0721	Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit	96
646764639	495	53.59	1	492	4	474	0.0e+00	494	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
646764640	491	55.89	1	491	2	481	0.0e+00	696	COG0064	Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit	483
646764641	279	35.09	1	265	14	270	3.0e-64	238	COG2326	Polyphosphate kinase 2, PPK2 family	270
646764642	259	40.3	2	254	1	260	6.0e-79	287	COG0708	Exonuclease III	261
646764646	381	49.87	1	375	8	368	2.0e-128	452	COG2021	Homoserine acetyltransferase	368
646764647	236	22.88	20	172	1	151	1.0e-06	47.3	COG1309	DNA-binding transcriptional regulator, AcrR family	201
646764648	255	24.3	19	219	6	214	1.0e-13	70.3	COG1011	FMN phosphatase YigB, HAD superfamily	229
646764649	299	52.22	30	297	1	264	2.0e-82	299	COG0548	Acetylglutamate kinase	265
646764650	436	23.39	84	414	4	329	4.0e-17	82.9	COG0642	Signal transduction histidine kinase	336
646764651	180	51.98	3	179	9	182	2.0e-54	205	COG4567	Two-component response regulator, ActR/RegA family, consists of REC and Fis-type HTH domains	182
646764652	448	66.82	1	448	1	444	0.0e+00	670	COG1220	ATP-dependent protease HslVU (ClpYQ), ATPase subunit	444
646764653	178	70.45	3	178	1	176	9.0e-75	272	COG5405	ATP-dependent protease HslVU (ClpYQ), peptidase subunit	178
646764654	139	57.5	21	139	1	120	1.0e-24	105	COG1734	RNA polymerase-binding transcription factor DksA	120
646764655	435	37.77	71	435	1	322	7.0e-85	307	COG0523	GTPase, G3E family	323
646764656	400	44.86	4	399	1	392	3.0e-112	398	COG1092	23S rRNA G2069 N7-methylase RlmK or C1962 C5-methylase RlmI	393
646764657	307	51.63	4	306	7	299	5.0e-88	318	COG4973	Site-specific recombinase XerC	299
646764658	252	26.51	1	249	4	216	1.0e-35	143	COG3159	Uncharacterized conserved protein YigA, DUF484 family	218
646764659	370	46.64	62	344	1	272	7.0e-91	327	COG0253	Diaminopimelate epimerase	272
646764660	294	34.9	1	294	12	307	1.0e-60	227	COG1560	Lauroyl/myristoyl acyltransferase	308
646764661	395	71.65	1	387	1	387	0.0e+00	676	COG0192	S-adenosylmethionine synthetase	388
646764663	253	24.62	1	249	6	251	1.0e-25	110	COG5285	Ectoine hydroxylase-related dioxygenase, phytanoyl-CoA dioxygenase (PhyH) family	299
646764665	347	38.84	13	336	1	314	1.0e-77	283	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
646764668	425	26.25	41	418	9	382	2.0e-25	110	COG2814	Predicted arabinose efflux permease, MFS family	394
646764669	526	39.09	37	497	1	452	1.0e-56	214	COG1538	Outer membrane protein TolC	457
646764670	436	28.84	25	398	3	369	2.0e-24	107	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
646764671	1060	28.79	2	1044	1	1009	0.0e+00	679	COG0841	Multidrug efflux pump subunit AcrB	1009
646764673	348	34.26	34	347	14	330	4.0e-52	198	COG2334	Ser/Thr protein kinase RdoA involved in Cpx stress response, MazF antagonist	331
646764675	237	29.09	21	237	3	211	3.0e-29	122	COG3295	Uncharacterized protein	213
646764676	340	33.74	6	331	1	278	1.0e-55	210	COG1975	Xanthine and CO dehydrogenase maturation factor, XdhC/CoxF family	278
646764677	208	40.94	1	148	1	146	1.0e-29	123	COG3427	Carbon monoxide dehydrogenase subunit G	146
646764678	421	46.25	19	404	9	395	2.0e-94	339	COG3552	Uncharacterized conserved protein, contains von Willebrand factor type A (vWA) domain	395
646764679	293	26.16	1	285	9	285	3.0e-34	139	COG0714	MoxR-like ATPase	329
646764680	265	37.99	1	263	1	279	4.0e-52	198	COG1319	CO or xanthine dehydrogenase, FAD-binding subunit	284
646764681	793	40.46	9	789	5	731	0.0e+00	620	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
646764682	174	57.42	3	156	2	156	6.0e-55	206	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
646764683	463	33.63	12	454	1	442	2.0e-36	147	COG0531	Amino acid transporter	466
646764684	218	38.86	3	212	1	211	5.0e-46	177	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
646764686	256	33.58	1	254	2	266	6.0e-52	197	COG1018	Ferredoxin-NADP reductase	266
646764688	265	24.24	17	265	10	258	1.0e-17	83.9	COG3568	Metal-dependent hydrolase, endonuclease/exonuclease/phosphatase family	259
646764691	368	35.29	1	364	1	371	1.0e-85	309	COG0579	L-2-hydroxyglutarate oxidase LhgO	429
646764693	518	35.26	19	512	8	475	2.0e-90	326	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
646764694	232	35.78	8	232	5	234	1.0e-43	169	COG0412	Dienelactone hydrolase	236
646764695	367	36.46	8	364	5	333	1.0e-51	197	COG2070	NAD(P)H-dependent flavin oxidoreductase YrpB, nitropropane dioxygenase family	336
646764696	381	37.22	21	373	1	357	6.0e-60	224	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
646764697	404	22.28	27	395	14	406	4.0e-16	79.5	COG0738	Fucose permease	422
646764698	220	25.11	10	211	11	231	1.0e-11	63.8	COG0748	Putative heme iron utilization protein	245
646764699	100	26.73	1	89	13	113	3.0e-11	60	COG2916	DNA-binding protein H-NS	128
646764700	427	39.93	11	297	6	292	2.0e-63	237	COG0053	Divalent metal cation (Fe/Co/Zn/Cd) transporter	304
646764701	152	46.71	1	152	4	154	4.0e-35	140	COG1522	DNA-binding transcriptional regulator, Lrp family	154
646764703	214	34.27	1	206	12	224	2.0e-32	132	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
646764704	201	41.95	17	190	16	185	2.0e-38	151	COG0797	Rare lipoprotein A, peptidoglycan hydrolase digesting "naked" glycans, contains C-terminal SPOR domain	233
646764706	278	28.11	29	277	1	229	2.0e-19	90	COG2801	Transposase InsO and inactivated derivatives	232
646764707	294	50.18	12	288	1	275	4.0e-84	304	COG0313	16S rRNA C1402 (ribose-2'-O) methylase RsmI	275
646764708	157	41.67	36	154	1	114	8.0e-26	109	COG0792	Predicted endonuclease distantly related to archaeal Holliday junction resolvase	114
646764709	195	61.02	4	180	3	176	4.0e-61	227	COG0279	Phosphoheptose isomerase	176
646764710	263	35.03	7	199	1	196	3.0e-28	118	COG2823	Osmotically-inducible protein OsmY, contains BON domain	196
646764711	117	46.23	16	117	4	109	9.0e-20	89	COG4654	Cytochrome c551/c552	110
646764715	947	24.9	6	932	2	861	2.0e-130	460	COG1743	Adenine-specific DNA methylase, contains a Zn-ribbon domain	875
646764716	967	18.75	10	797	2	774	3.0e-106	380	COG1483	Predicted ATPase, AAA+ superfamily	774
646764734	133	28.57	19	118	2	106	2.0e-09	54.9	COG2963	Transposase and inactivated derivatives	116
646764735	297	22.31	49	297	1	231	3.0e-12	66.2	COG2801	Transposase InsO and inactivated derivatives	232
646764738	368	25.66	15	162	16	156	6.0e-16	79	COG3666	Transposase	161
646764743	95	40.74	5	83	4	81	1.0e-09	54.9	COG2336	Antitoxin component of the MazEF toxin-antitoxin module	82
646764745	364	19.94	14	329	2	281	5.0e-07	49.1	COG4974	Site-specific recombinase XerD	300
646764746	195	48.21	127	182	13	68	3.0e-09	54.9	COG3311	Predicted DNA-binding transcriptional regulator AlpA	70
646764750	435	39.78	18	429	4	437	1.0e-74	273	COG2233	Xanthine/uracil permease	451
646764751	551	35.86	1	448	6	429	5.0e-62	232	COG0025	NhaP-type Na+/H+ or K+/H+ antiporter	429
646764752	428	34.89	26	258	9	241	1.0e-39	157	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
646764753	231	40.33	2	230	1	241	6.0e-44	170	COG3142	Copper homeostasis protein CutC	241
646764754	1195	31.43	26	702	1	634	0.0e+00	527	COG4231	TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit	640
646764759	302	30.31	23	302	27	307	3.0e-35	142	COG0524	Sugar or nucleoside kinase, ribokinase family	311
646764760	433	36.39	18	408	3	380	4.0e-87	315	COG2942	Mannose or cellobiose epimerase, N-acyl-D-glucosamine 2-epimerase family	388
646764761	328	38.69	3	323	1	329	4.0e-61	228	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
646764762	341	37.15	8	330	9	316	8.0e-65	240	COG0385	Predicted Na+-dependent transporter	319
646764764	361	20.21	14	361	2	354	5.0e-31	128	COG3203	Outer membrane protein (porin)	354
646764765	310	33.33	3	298	2	297	6.0e-35	141	COG0583	DNA-binding transcriptional regulator, LysR family	297
646764766	1130	38.43	563	1130	3	548	0.0e+00	529	COG1884	Methylmalonyl-CoA mutase, N-terminal domain/subunit	548
646764767	319	35.89	7	317	10	334	2.0e-69	256	COG2070	NAD(P)H-dependent flavin oxidoreductase YrpB, nitropropane dioxygenase family	336
646764768	296	27.7	21	294	16	282	8.0e-20	91.3	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
646764769	156	36.91	13	155	6	154	7.0e-25	106	COG1522	DNA-binding transcriptional regulator, Lrp family	154
646764770	312	23.41	59	307	49	291	2.0e-08	53	COG5006	Threonine/homoserine efflux transporter RhtA	292
646764771	305	23.7	1	209	9	218	9.0e-20	91.1	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
646764772	157	35.83	28	145	42	159	9.0e-11	59.7	COG2030	Acyl dehydratase	159
646764774	173	31.91	30	168	14	153	5.0e-23	100	COG2606	Cys-tRNA(Pro) deacylase, prolyl-tRNA editing enzyme YbaK/EbsC	155
646764775	308	25.75	5	298	1	288	2.0e-55	209	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
646764776	313	34.84	12	313	21	324	5.0e-56	211	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
646764777	200	37.35	11	169	3	166	4.0e-34	137	COG3545	Predicted esterase of the alpha/beta hydrolase fold	181
646764778	345	56.68	11	341	8	344	3.0e-127	448	COG1613	ABC-type sulfate transport system, periplasmic component	348
646764779	366	58.28	32	343	13	324	1.0e-116	413	COG0502	Biotin synthase or related enzyme	335
646764780	246	44.25	12	237	4	222	5.0e-55	207	COG0132	Dethiobiotin synthetase	223
646764781	394	48.22	1	390	1	388	1.0e-103	369	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
646764782	453	43.88	12	453	3	449	0.0e+00	469	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
646764783	435	26.86	85	314	12	234	5.0e-17	82.7	COG0412	Dienelactone hydrolase	236
646764784	151	41.73	14	149	5	129	8.0e-29	119	COG3012	Uncharacterized conserved protein YchJ, contains N- and C-terminal SEC-C domains	151
646764785	376	47.27	1	376	3	387	3.0e-94	339	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
646764786	225	23.92	1	195	6	207	8.0e-18	84.2	COG0300	Short-chain dehydrogenase	265
646764787	402	41.15	12	399	2	388	5.0e-77	281	COG0183	Acetyl-CoA acetyltransferase	392
646764788	605	44.46	8	585	1	573	0.0e+00	768	COG4579	Isocitrate dehydrogenase kinase/phosphatase	578
646764789	134	35.78	5	113	1	106	8.0e-15	72.9	COG0789	DNA-binding transcriptional regulator, MerR family	124
646764790	357	20.94	19	294	1	235	6.0e-16	78.7	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
646764794	528	33.39	7	526	27	551	8.0e-87	314	COG0747	ABC-type transport system, periplasmic component	556
646764796	257	28.24	6	251	8	262	1.0e-33	137	COG0300	Short-chain dehydrogenase	265
646764798	269	25.91	1	269	1	264	4.0e-21	95.1	COG3087	Cell division protein FtsN	264
646764799	596	41.51	9	596	3	577	0.0e+00	534	COG0018	Arginyl-tRNA synthetase	577
646764802	905	56.49	1	875	8	842	0.0e+00	1130	COG1410	Methionine synthase I, cobalamin-binding domain	842
646764803	356	58.1	17	342	2	311	5.0e-114	404	COG0646	Methionine synthase I (cobalamin-dependent), methyltransferase domain	311
646764805	262	29.32	18	261	19	282	2.0e-20	93.2	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
646764807	308	32.93	51	299	1	246	5.0e-39	155	COG1414	DNA-binding transcriptional regulator, IclR family	246
646764808	327	24.84	4	325	1	264	1.0e-39	157	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
646764810	417	29.89	48	416	1	364	3.0e-44	172	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
646764811	285	34.21	46	271	30	255	1.0e-39	157	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
646764816	279	25.56	6	271	1	249	2.0e-33	136	COG1521	Pantothenate kinase type III	251
646764817	312	36.82	50	306	1	236	5.0e-46	178	COG0340	Biotin-(acetyl-CoA carboxylase) ligase	238
646764818	389	38.75	117	387	1	266	1.0e-55	210	COG0767	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, permease component MlaE	267
646764819	292	53.1	19	276	6	263	2.0e-87	315	COG1127	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, ATPase component MlaF	263
646764820	325	21.02	1	310	1	305	2.0e-18	86.7	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
646764821	208	23.12	12	203	10	204	5.0e-08	51.5	COG3218	ABC-type uncharacterized transport system, auxiliary component	205
646764822	385	24.14	8	148	21	148	4.0e-09	56.5	COG5652	VanZ like family protein (function unknown)	148
646764823	107	52.63	50	106	1	57	2.0e-16	77.3	COG3411	(2Fe-2S) ferredoxin	64
646764824	214	39.61	9	214	8	205	3.0e-50	191	COG2945	Alpha/beta superfamily hydrolase	210
646764825	409	44.56	18	409	4	389	2.0e-104	373	COG1686	D-alanyl-D-alanine carboxypeptidase	389
646764826	319	33.11	10	294	1	276	6.0e-40	158	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
646764827	89	37.08	1	89	2	90	1.0e-23	101	COG2921	Putative lipoic acid-binding regulatory protein	90
646764828	327	31.63	9	297	3	296	4.0e-35	142	COG0583	DNA-binding transcriptional regulator, LysR family	297
646764830	241	49.55	8	230	2	216	1.0e-72	266	COG0321	Lipoate-protein ligase B	221
646764831	335	63.93	30	332	1	303	0.0e+00	487	COG0320	Lipoate synthase	306
646764832	278	28.11	29	277	1	229	3.0e-19	89.3	COG2801	Transposase InsO and inactivated derivatives	232
646764834	250	36.29	15	250	5	251	4.0e-43	168	COG0584	Glycerophosphoryl diester phosphodiesterase	257
646764835	426	51.71	2	406	1	402	8.0e-103	367	COG1301	Na+/H+-dicarboxylate symporter	415
646764836	698	44.82	62	683	5	602	0.0e+00	565	COG4191	Signal transduction histidine kinase regulating C4-dicarboxylate transport system	603
646764837	449	48.48	1	444	1	459	0.0e+00	499	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
646764838	178	28.12	30	156	1	127	3.0e-12	65.3	COG0526	Thiol-disulfide isomerase or thioredoxin	127
646764840	540	50.86	16	535	2	486	0.0e+00	531	COG0606	Predicted ATPase with chaperone activity	490
646764841	97	37.08	6	91	1	89	2.0e-16	77.7	COG2960	Uncharacterized conserved protein YqiC, BMFP domain	103
646764842	112	75	1	112	1	112	3.0e-40	156	COG0347	Nitrogen regulatory protein PII	112
646764843	502	57.95	99	499	1	399	2.0e-123	436	COG0004	Ammonia channel protein AmtB	409
646764845	318	38.91	1	318	1	316	1.0e-62	233	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
646764846	175	35.43	1	123	1	126	1.0e-20	92.7	COG2893	Phosphotransferase system, mannose/fructose-specific component IIA	143
646764847	89	50	1	88	1	88	1.0e-22	98	COG1925	Phosphotransferase system, HPr and related phosphotransfer proteins	88
646764848	581	45.22	3	577	1	568	0.0e+00	621	COG1080	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria)	574
646764849	252	50.2	1	248	3	254	6.0e-69	253	COG0476	Molybdopterin or thiamine biosynthesis adenylyltransferase	254
646764850	527	42.99	12	425	7	406	4.0e-100	358	COG0793	C-terminal processing protease CtpA/Prc, contains a PDZ domain	406
646764851	248	68.26	1	230	1	230	1.0e-103	369	COG0588	Phosphoglycerate mutase (BPG-dependent)	230
646764852	141	34.31	36	136	7	108	8.0e-17	79.6	COG0607	Rhodanese-related sulfurtransferase	110
646764853	86	48.72	3	79	2	79	1.0e-20	91.6	COG0695	Glutaredoxin	80
646764854	158	52.94	1	153	4	156	1.0e-45	175	COG1952	Preprotein translocase subunit SecB	157
646764855	332	51.95	1	332	2	329	2.0e-102	365	COG0240	Glycerol-3-phosphate dehydrogenase	329
646764856	186	51.25	19	172	11	169	1.0e-42	166	COG2110	O-acetyl-ADP-ribose deacetylase (regulator of RNase III), contains Macro domain	179
646764857	156	57.69	1	156	2	155	1.0e-62	231	COG0219	tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain	155
646764858	261	38.08	24	260	1	225	2.0e-36	146	COG1040	Predicted amidophosphoribosyltransferases	225
646764859	321	22.87	21	229	16	208	1.0e-15	77.2	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
646764860	158	28.29	10	157	11	161	1.0e-21	95.8	COG5488	Uncharacterized membrane protein	164
646764861	538	29.93	16	293	1	242	1.0e-56	214	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
646764862	537	56.56	24	536	4	517	0.0e+00	562	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
646764863	207	43.55	9	187	5	186	9.0e-48	183	COG3175	Cytochrome c oxidase assembly protein Cox11	195
646764865	285	36.75	52	285	1	206	3.0e-39	155	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
646764867	238	32.1	2	238	11	250	2.0e-36	146	COG3346	Cytochrome oxidase assembly protein ShyY1	252
646764868	224	20.49	36	219	1	205	1.0e-08	53.5	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
646764869	369	28.41	14	356	4	318	2.0e-39	157	COG1612	Heme A synthase	323
646764870	301	49.47	12	296	16	300	3.0e-86	312	COG0109	Polyprenyltransferase (heme O synthase)	304
646764871	209	37.5	3	209	2	205	9.0e-43	166	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
646764872	96	22.83	1	92	3	90	4.0e-10	56.1	COG2350	Uncharacterized conserved protein YciI, contains a putative active-site phosphohistidine	92
646764873	270	55.15	1	270	1	268	3.0e-91	327	COG1464	ABC-type metal ion transport system, periplasmic component/surface antigen	268
646764874	308	30.19	31	136	15	120	1.0e-07	50.7	COG1846	DNA-binding transcriptional regulator, MarR family	126
646764875	244	41.56	16	242	6	236	3.0e-51	195	COG2188	DNA-binding transcriptional regulator, GntR family	236
646764876	367	43.16	1	365	4	380	8.0e-97	347	COG1820	N-acetylglucosamine-6-phosphate deacetylase	380
646764877	338	37.06	1	337	2	340	2.0e-71	262	COG2222	Fructoselysine-6-P-deglycase FrlB and related proteins with duplicated sugar isomerase (SIS) domain	340
646764878	865	42.83	302	857	1	565	0.0e+00	539	COG1080	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria)	574
646764879	603	39.81	1	379	1	393	5.0e-76	279	COG1263	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific	393
646764881	378	46.68	1	373	2	346	2.0e-80	292	COG1294	Cytochrome bd-type quinol oxidase, subunit 2	346
646764884	311	37.81	29	308	59	332	1.0e-67	250	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
646764888	391	27.59	82	369	5	284	5.0e-43	168	COG0547	Anthranilate phosphoribosyltransferase	338
646764889	232	41.84	3	232	31	263	2.0e-64	239	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
646764890	214	32.11	1	214	1	210	1.0e-30	126	COG0625	Glutathione S-transferase	211
646764891	384	49.85	58	383	8	340	2.0e-102	365	COG0552	Signal recognition particle GTPase	340
646764892	204	40.43	22	202	2	187	5.0e-47	180	COG0742	16S rRNA G966 N2-methylase RsmD	187
646764893	169	55.06	1	158	2	159	3.0e-61	227	COG0669	Phosphopantetheine adenylyltransferase	159
646764898	359	41.39	5	355	2	353	6.0e-82	298	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
646764899	201	50.51	1	198	1	188	1.0e-70	259	COG0193	Peptidyl-tRNA hydrolase	190
646764900	205	47.31	1	93	2	93	8.0e-22	97.3	COG1825	Ribosomal protein L25 (general stress protein Ctc)	93
646764901	318	61.34	5	315	3	313	3.0e-120	424	COG0462	Phosphoribosylpyrophosphate synthetase	314
646764903	293	45.04	11	288	6	286	5.0e-81	294	COG1947	4-diphosphocytidyl-2C-methyl-D-erythritol kinase	289
646764904	210	25.64	21	210	12	202	7.0e-26	110	COG3017	Outer membrane lipoprotein LolB, involved in outer membrane biogenesis	206
646764906	276	49.1	1	276	1	273	2.0e-90	325	COG0266	Formamidopyrimidine-DNA glycosylase	273
646764907	377	49.86	24	372	7	340	6.0e-109	387	COG1194	Adenine-specific DNA glycosylase, acts on AG and A-oxoG pairs	342
646764908	211	32.08	1	209	2	208	4.0e-32	131	COG2802	Uncharacterized protein, similar to the N-terminal domain of Lon protease	221
646764909	312	49.83	16	300	1	283	3.0e-95	342	COG1660	RNase adaptor protein for sRNA GlmZ degradation, contains a P-loop ATPase domain	286
646764910	322	38.51	5	312	2	304	3.0e-83	301	COG1493	Serine kinase of the HPr protein, regulates carbohydrate metabolism	308
646764911	171	34.67	23	170	1	150	6.0e-30	123	COG1762	Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type)	152
646764912	118	43.4	1	106	1	103	8.0e-23	99.2	COG1544	Ribosome-associated translation inhibitor RaiA	110
646764913	505	43.87	1	505	1	443	0.0e+00	467	COG1508	DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog	444
646764914	265	68.16	21	265	3	243	4.0e-106	377	COG1137	ABC-type lipopolysaccharide export system, ATPase component	243
646764915	223	33.89	20	197	1	163	1.0e-22	100	COG1934	Lipopolysaccharide export system protein LptA	173
646764916	195	27.12	10	186	8	180	1.0e-27	116	COG3117	Lipopolysaccharide export system protein LptC	188
646764917	186	51.5	8	174	1	167	4.0e-57	213	COG1778	 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsC and related HAD superfamily phosphatases	170
646764918	327	58.42	10	210	1	202	2.0e-65	242	COG0794	D-arabinose 5-phosphate isomerase GutQ	202
646764919	688	39.21	23	399	3	380	7.0e-65	242	COG0475	Kef-type K+ transport system, membrane component KefB	397
646764920	188	44	11	185	3	177	2.0e-41	161	COG0503	Adenine/guanine phosphoribosyltransferase or related PRPP-binding protein	179
646764921	204	48.54	1	203	3	206	2.0e-28	119	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
646764923	289	60.92	6	289	7	287	1.0e-123	436	COG0788	Formyltetrahydrofolate hydrolase	287
646764924	408	21.99	1	407	5	406	1.0e-31	131	COG3182	Uncharacterized iron-regulated membrane protein	442
646764925	361	19.13	19	359	1	341	7.0e-13	68.4	COG0628	Predicted PurR-regulated permease PerM	355
646764926	957	67.44	1	952	3	935	0.0e+00	1574	COG0178	Excinuclease UvrABC ATPase subunit	935
646764927	395	18.81	4	385	1	382	3.0e-14	73.3	COG2814	Predicted arabinose efflux permease, MFS family	394
646764928	177	42.78	2	177	1	167	7.0e-38	150	COG0629	Single-stranded DNA-binding protein	167
646764930	548	39.83	184	517	50	408	5.0e-48	185	COG0840	Methyl-accepting chemotaxis protein	408
646764931	268	37.04	75	181	8	114	1.0e-15	77	COG2863	Cytochrome c553	121
646764932	541	25.51	4	472	16	480	3.0e-53	203	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
646764936	241	30.16	13	138	4	121	1.0e-13	70.4	COG2863	Cytochrome c553	121
646764937	297	29.87	6	297	1	292	5.0e-26	112	COG0583	DNA-binding transcriptional regulator, LysR family	297
646764938	449	19.64	47	428	54	427	1.0e-10	61.4	COG2271	Sugar phosphate permease	448
646764939	222	28.92	4	206	1	199	2.0e-29	122	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
646764940	229	31.75	12	221	2	209	6.0e-37	147	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
646764941	214	35.21	5	214	1	209	3.0e-37	148	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
646764942	248	35.95	1	232	1	241	6.0e-35	141	COG0580	Glycerol uptake facilitator and related aquaporins (Major Intrinsic Protein Family)	241
646764944	1415	38.43	761	1014	93	335	5.0e-45	177	COG0642	Signal transduction histidine kinase	336
646764946	322	37.58	1	306	1	312	1.0e-40	160	COG0657	Acetyl esterase/lipase	312
646764948	531	19.11	5	432	1	362	1.0e-13	71.4	COG2814	Predicted arabinose efflux permease, MFS family	394
646764949	167	38.21	15	136	5	126	4.0e-11	61.1	COG1846	DNA-binding transcriptional regulator, MarR family	126
646764950	425	29.32	29	425	2	368	3.0e-69	256	COG3616	D-serine deaminase, pyridoxal phosphate-dependent	368
646764951	325	35.48	40	316	4	281	6.0e-51	194	COG1737	DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains	281
646764952	493	38.65	9	482	7	569	9.0e-125	440	COG3653	N-acyl-D-aspartate/D-glutamate deacylase	579
646764953	128	35.65	16	126	16	130	2.0e-24	104	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
646764954	274	54.96	1	130	7	137	3.0e-47	182	COG2904	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF, N-terminal domain	137
646764956	507	49.86	5	345	7	347	1.0e-113	403	COG1171	Threonine dehydratase	347
646764957	1368	20.8	909	1348	1	388	1.0e-45	179	COG0247	Fe-S oxidoreductase	388
646764958	142	24.09	1	128	1	137	3.0e-20	91.2	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
646764959	137	54.62	8	126	2	120	2.0e-42	164	COG3536	Uncharacterized conserved protein, DUF971 family	120
646764960	243	57.98	8	242	1	237	8.0e-79	286	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
646764961	334	22.03	71	332	3	281	1.0e-24	107	COG4395	Predicted lipid-binding transport protein, Tim44 family	281
646764962	214	26.63	3	198	6	204	4.0e-25	108	COG3165	Ubiquinone biosynthesis protein UbiJ, contains SCP2 domain	204
646764963	525	43.02	2	519	6	517	0.0e+00	467	COG0661	Predicted unusual protein kinase regulating ubiquinone biosynthesis, AarF/ABC1/UbiB family	517
646764965	110	43.42	1	76	8	82	3.0e-17	80.1	COG2331	Predicted nucleic acid-binding protein, contains Zn-ribbon domain	82
646764966	230	47.39	20	229	6	213	1.0e-59	222	COG2928	Uncharacterized membrane protein	222
646764967	599	63.47	3	593	1	583	0.0e+00	923	COG0173	Aspartyl-tRNA synthetase	585
646764968	171	20.3	5	136	8	134	6.0e-07	47.3	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
646764969	419	35.11	23	403	52	432	5.0e-58	218	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
646764970	199	15.56	2	181	8	182	5.0e-06	44.6	COG1309	DNA-binding transcriptional regulator, AcrR family	201
646764971	595	31.93	37	458	7	388	4.0e-72	266	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
646764972	811	36.48	6	310	3	299	9.0e-69	255	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
646764973	399	40.34	6	399	2	392	2.0e-81	296	COG0183	Acetyl-CoA acetyltransferase	392
646764974	259	36.72	4	255	3	257	7.0e-46	177	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
646764975	294	45.53	42	287	21	258	2.0e-63	236	COG1526	Formate dehydrogenase assembly factor FdhD	266
646764978	203	28.23	1	202	1	203	5.0e-21	94.5	COG0625	Glutathione S-transferase	211
646764979	131	44.53	1	128	3	129	2.0e-37	147	COG1607	Acyl-CoA hydrolase	157
646764980	632	63.05	109	605	1	495	0.0e+00	672	COG5265	ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components	497
646764982	355	41.14	10	348	11	348	1.0e-77	284	COG3178	Predicted phosphotransferase, aminoglycoside/choline kinase (APH/ChoK) family	351
646764983	790	26.44	20	784	2	783	5.0e-117	415	COG1452	LPS assembly outer membrane protein LptD (organic solvent tolerance protein OstA)	784
646764984	477	21	39	319	5	266	4.0e-14	73.2	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
646764985	336	53.45	14	336	6	332	2.0e-105	375	COG1995	4-hydroxy-L-threonine phosphate dehydrogenase PdxA	332
646764986	280	46.39	15	274	4	257	9.0e-77	280	COG0030	16S rRNA A1518 and A1519 N6-dimethyltransferase RsmA/KsgA/DIM1 (may also have DNA glycosylase/AP lyase activity)	259
646764988	131	29.08	1	125	1	138	4.0e-13	67.2	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
646764989	278	31.94	19	269	4	266	1.0e-33	137	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
646764990	238	46.98	4	217	7	221	5.0e-48	184	COG0765	ABC-type amino acid transport system, permease component	222
646764991	214	49.52	5	211	10	217	4.0e-52	198	COG0765	ABC-type amino acid transport system, permease component	222
646764992	250	60.42	9	248	1	240	1.0e-102	366	COG1126	ABC-type polar amino acid transport system, ATPase component	240
646764993	249	26.34	10	249	1	243	2.0e-35	143	COG1414	DNA-binding transcriptional regulator, IclR family	246
646764994	297	30.51	62	296	4	223	2.0e-44	173	COG1451	Predicted metal-dependent hydrolase	223
646764995	252	27.87	8	246	1	237	2.0e-31	130	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
646764996	184	42.44	4	175	5	173	1.0e-46	178	COG0241	Histidinol phosphatase or a related phosphatase	181
646764997	699	48.42	8	698	5	690	0.0e+00	750	COG0751	Glycyl-tRNA synthetase, beta subunit	691
646764998	335	71.29	1	303	4	298	0.0e+00	540	COG0752	Glycyl-tRNA synthetase, alpha subunit	298
646764999	157	34.55	16	70	4	58	3.0e-06	44.8	COG1476	DNA-binding transcriptional regulator, XRE-family HTH domain	68
646765009	212	33.1	68	207	2	143	3.0e-16	78.9	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
646765015	236	32.34	9	236	1	230	3.0e-25	108	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
646765019	289	31.5	47	288	53	301	2.0e-33	136	COG4714	Uncharacterized membrane-anchored protein	303
646765024	649	38.34	5	644	6	636	9.0e-103	368	COG4248	Uncharacterized protein with protein kinase and helix-hairpin-helix DNA-binding domains	637
646765026	225	57.49	23	225	1	207	4.0e-62	231	COG4245	Uncharacterized conserved protein YegL, contains vWA domain of TerY type	207
646765036	757	26.25	82	749	58	694	6.0e-66	246	COG0507	ATP-dependent exoDNAse (exonuclease V), alpha subunit, helicase superfamily I	696
646765041	459	28.06	30	413	13	410	3.0e-96	345	COG0069	Glutamate synthase domain 2	485
646765042	420	55.56	1	369	1	356	0.0e+00	480	COG0482	tRNA U34 2-thiouridine synthase MnmA/TrmU, contains the PP-loop ATPase domain	356
646765043	159	32.17	8	121	9	120	5.0e-10	57.3	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
646765044	380	53.87	2	375	1	356	4.0e-108	385	COG3288	NAD/NADP transhydrogenase alpha subunit	356
646765046	483	67.01	1	482	1	463	0.0e+00	613	COG1282	NAD/NADP transhydrogenase beta subunit	463
646765048	127	34.68	1	123	3	124	7.0e-20	89.6	COG3324	Predicted enzyme related to lactoylglutathione lyase	127
646765049	516	37.25	131	513	1	408	1.0e-47	184	COG0840	Methyl-accepting chemotaxis protein	408
646765050	428	38.41	1	412	1	376	6.0e-100	358	COG0116	23S rRNA G2445 N2-methylase RlmL	381
646765051	249	29.1	26	210	6	190	2.0e-16	80	COG3009	Uncharacterized lipoprotein YmbA	190
646765052	553	35.91	25	552	7	544	2.0e-130	459	COG3008	Paraquat-inducible protein B	553
646765055	186	42.61	9	184	4	179	1.0e-38	152	COG3038	Cytochrome b561	181
646765056	187	32.61	9	184	8	191	5.0e-29	120	COG2353	Polyisoprenoid-binding periplasmic protein YceI	192
646765057	192	45.6	1	192	1	192	1.0e-46	179	COG2353	Polyisoprenoid-binding periplasmic protein YceI	192
646765059	316	47.37	1	303	1	302	2.0e-83	302	COG0341	Preprotein translocase subunit SecF	305
646765060	695	50.2	109	613	16	506	5.0e-130	458	COG0342	Preprotein translocase subunit SecD	506
646765061	109	54.95	19	109	7	97	6.0e-26	109	COG1862	Preprotein translocase subunit YajC	97
646765062	396	60	21	395	1	369	0.0e+00	531	COG0343	Queuine/archaeosine tRNA-ribosyltransferase	372
646765063	352	58.03	4	352	3	347	0.0e+00	463	COG0809	S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase)	348
646765064	762	54.55	77	754	20	676	0.0e+00	824	COG1200	RecG-like helicase	677
646765065	319	31.15	1	303	1	289	2.0e-39	156	COG0583	DNA-binding transcriptional regulator, LysR family	297
646765067	484	61.04	1	475	11	488	0.0e+00	682	COG0753	Catalase	496
646765069	165	53.59	13	165	4	156	2.0e-50	191	COG0783	DNA-binding ferritin-like protein (oxidative damage protectant)	156
646765070	287	40.93	1	280	6	286	1.0e-47	183	COG0382	4-hydroxybenzoate polyprenyltransferase	289
646765071	271	43.98	1	265	2	264	9.0e-65	240	COG0345	Pyrroline-5-carboxylate reductase	266
646765072	240	59.47	13	238	4	228	2.0e-82	298	COG0325	Uncharacterized pyridoxal phosphate-containing protein, affects Ilv metabolism, UPF0001 family	228
646765073	408	29.46	16	406	2	385	9.0e-61	227	COG0247	Fe-S oxidoreductase	388
646765074	362	28.17	2	362	40	459	1.0e-36	147	COG0277	FAD/FMN-containing dehydrogenase	459
646765075	497	39.05	22	472	1	458	2.0e-89	323	COG0277	FAD/FMN-containing dehydrogenase	459
646765076	472	40.57	27	469	8	458	2.0e-91	330	COG0277	FAD/FMN-containing dehydrogenase	459
646765077	184	54.44	2	179	1	180	1.0e-58	219	COG2096	Cob(I)alamin adenosyltransferase	184
646765078	110	31.96	14	110	2	90	3.0e-14	70.4	COG5606	Predicted DNA-binding protein, XRE-type HTH domain	91
646765079	114	54	5	104	8	107	4.0e-28	116	COG4679	Phage-related protein	116
646765080	357	66.76	3	350	2	350	0.0e+00	579	COG0722	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase	351
646765081	488	42.46	25	487	1	454	3.0e-122	432	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
646765082	287	40.44	21	285	1	263	1.0e-58	220	COG0388	Predicted amidohydrolase	274
646765083	1420	23.67	28	1413	2	1271	0.0e+00	477	COG3164	Uncharacterized conserved protein YhdP, contains DUF3971 and AsmA2 domains	1271
646765084	931	44.12	11	931	55	955	0.0e+00	774	COG1391	Glutamine synthetase adenylyltransferase	963
646765085	555	47.59	1	555	1	554	0.0e+00	542	COG0497	DNA repair ATPase RecN	557
646765086	304	39.86	8	290	1	281	7.0e-64	237	COG0061	NAD kinase	281
646765087	363	42.15	25	363	3	343	6.0e-88	317	COG1420	Transcriptional regulator of heat shock response	346
646765088	356	45.87	16	342	5	320	8.0e-98	350	COG0276	Protoheme ferro-lyase (ferrochelatase)	320
646765089	135	44.68	6	99	2	95	2.0e-22	98.5	COG1188	Ribosomal 50S subunit-recycling heat shock protein, contains S4 domain	100
646765090	195	41.92	2	195	5	193	1.0e-36	145	COG0576	Molecular chaperone GrpE (heat shock protein)	193
646765091	649	58.95	1	608	4	579	0.0e+00	658	COG0443	Molecular chaperone DnaK (HSP70)	579
646765092	379	61.42	1	379	1	370	0.0e+00	513	COG0484	DnaJ-class molecular chaperone with C-terminal Zn finger domain	371
646765094	271	55.89	11	271	1	263	2.0e-99	355	COG0413	Ketopantoate hydroxymethyltransferase	268
646765095	226	31.88	19	216	6	212	2.0e-35	142	COG1428	Deoxyadenosine/deoxycytidine kinase	216
646765096	180	48.43	1	158	1	159	6.0e-47	180	COG0801	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase	160
646765097	531	35.89	76	483	1	393	5.0e-79	288	COG0617	tRNA nucleotidyltransferase/poly(A) polymerase	412
646765098	228	29.86	1	221	4	202	1.0e-34	139	COG0560	Phosphoserine phosphatase	212
646765100	355	60.35	16	355	3	345	0.0e+00	494	COG0150	Phosphoribosylaminoimidazole (AIR) synthetase	345
646765101	314	48.53	8	314	5	305	2.0e-94	339	COG0324	tRNA A37 N6-isopentenylltransferase MiaA	308
646765102	698	41.99	33	697	4	638	0.0e+00	623	COG0323	DNA mismatch repair ATPase MutL	638
646765103	223	37.13	14	215	1	200	8.0e-32	130	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
646765104	272	33.46	15	260	36	289	8.0e-32	130	COG0668	Small-conductance mechanosensitive channel	316
646765109	249	26.22	25	249	43	262	6.0e-28	117	COG1729	Periplasmic TolA-binding protein (function unknown)	262
646765110	168	31.69	1	166	5	187	3.0e-32	131	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
646765111	430	40.23	9	429	1	425	1.0e-84	307	COG0823	Periplasmic component of the Tol biopolymer transport system	425
646765113	148	37.58	1	148	1	135	3.0e-26	111	COG0848	Biopolymer transport protein ExbD	137
646765114	225	44.6	12	224	1	213	2.0e-47	182	COG0811	Biopolymer transport protein ExbB/TolQ	216
646765115	154	44.36	13	145	2	133	3.0e-34	137	COG0824	Acyl-CoA thioesterase FadM	137
646765116	248	58.75	2	240	8	246	4.0e-86	311	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
646765117	415	68.84	4	415	2	413	0.0e+00	668	COG0112	Glycine/serine hydroxymethyltransferase	413
646765118	160	58.39	1	149	1	149	3.0e-52	197	COG1327	Transcriptional regulator NrdR, contains Zn-ribbon and ATP-cone domains	156
646765119	186	23.86	6	178	2	169	3.0e-14	72	COG4970	Tfp pilus assembly protein FimT	181
646765123	143	28.77	2	140	1	139	1.0e-14	72.3	COG4968	Tfp pilus assembly protein PilE	139
646765125	129	35.4	15	126	18	128	2.0e-19	87.7	COG5393	Uncharacterized membrane protein YqjE	131
646765126	100	38.78	3	100	7	104	1.0e-19	88	COG4575	Membrane-anchored ribosome-binding protein, inhibits growth in stationary phase, ElaB/YqjD/DUF883 family	104
646765127	212	40.4	1	192	1	194	4.0e-60	224	COG0450	Alkyl hydroperoxide reductase subunit AhpC (peroxiredoxin)	194
646765128	396	37.15	15	396	1	393	2.0e-84	305	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
646765129	261	33.47	19	259	2	242	2.0e-36	146	COG1414	DNA-binding transcriptional regulator, IclR family	246
646765130	277	21.99	42	268	16	236	2.0e-07	50.3	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
646765131	451	21.73	17	443	6	393	2.0e-18	87.2	COG2814	Predicted arabinose efflux permease, MFS family	394
646765132	448	65.65	21	448	5	427	0.0e+00	579	COG3508	Homogentisate 1,2-dioxygenase	427
646765133	432	20.07	113	389	37	259	5.0e-24	105	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
646765135	386	21.69	9	377	15	391	3.0e-10	60.2	COG2814	Predicted arabinose efflux permease, MFS family	394
646765138	385	45.05	1	382	11	393	8.0e-65	241	COG2814	Predicted arabinose efflux permease, MFS family	394
646765140	277	38.87	9	252	3	249	6.0e-38	151	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
646765142	331	47.62	1	331	1	324	5.0e-92	331	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
646765143	407	38.18	27	405	3	383	6.0e-82	298	COG0075	Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism protein PucG	383
646765144	396	22.25	9	388	3	391	2.0e-19	90.5	COG3919	Predicted ATP-dependent carboligase, ATP-grasp superfamily	415
646765147	414	20.85	69	387	48	373	5.0e-14	72.4	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
646765149	739	22.78	10	471	2	456	2.0e-41	164	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
646765150	366	22.9	57	350	35	339	2.0e-06	46.9	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
646765152	305	27.03	6	261	4	248	3.0e-36	146	COG1216	Glycosyltransferase, GT2 family	305
646765154	429	21.32	7	412	12	417	3.0e-18	86.7	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
646765155	403	21.88	46	397	42	393	6.0e-08	52.5	COG2814	Predicted arabinose efflux permease, MFS family	394
646765157	505	50.99	2	501	6	493	0.0e+00	599	COG4630	Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A	493
646765158	789	61.28	21	786	19	781	0.0e+00	1147	COG4631	Xanthine dehydrogenase, molybdopterin-binding subunit B	781
646765160	327	24.83	8	308	1	297	3.0e-27	116	COG0583	DNA-binding transcriptional regulator, LysR family	297
646765161	219	28.42	12	186	12	196	6.0e-15	74.2	COG3917	2-hydroxychromene-2-carboxylate isomerase	203
646765162	467	27.86	31	331	3	316	5.0e-23	102	COG2358	TRAP-type uncharacterized transport system, periplasmic component	321
646765165	262	32.44	1	262	1	253	1.0e-07	50.4	COG0730	Uncharacterized membrane protein YfcA	258
646765166	215	30.29	3	208	2	201	1.0e-12	66.4	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
646765167	297	30.69	9	296	6	290	4.0e-25	108	COG0583	DNA-binding transcriptional regulator, LysR family	297
646765169	417	39.9	19	404	1	390	8.0e-98	350	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
646765172	331	29.04	16	329	5	326	1.0e-33	137	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
646765173	533	41.62	29	395	2	333	3.0e-102	366	COG0836	Mannose-1-phosphate guanylyltransferase	333
646765174	461	46.41	253	461	24	226	2.0e-65	243	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
646765175	379	35.4	72	297	28	239	1.0e-36	147	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
646765176	747	23.82	10	484	4	457	2.0e-38	154	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
646765180	96	61.46	1	96	1	96	1.0e-32	131	COG0234	Co-chaperonin GroES (HSP10)	96
646765181	546	48.36	1	534	1	524	0.0e+00	491	COG0459	Chaperonin GroEL (HSP60 family)	524
646765182	212	59.14	12	197	7	192	3.0e-74	271	COG0529	Adenylylsulfate kinase or related kinase	197
646765184	288	29.25	5	254	2	252	1.0e-35	143	COG0351	Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase	263
646765185	56	53.7	3	56	1	54	6.0e-14	69.1	COG1773	Rubredoxin	55
646765187	192	52.85	1	192	4	194	2.0e-60	225	COG1678	Putative transcriptional regulator, AlgH/UPF0301 family	194
646765188	146	43.38	10	140	3	138	7.0e-35	139	COG0816	RNase H-fold protein, predicted Holliday junction resolvase in Firmicutes and mycoplasms, involved in anti-termination at Rho-dependent terminators	141
646765189	179	42.01	4	165	7	169	3.0e-38	151	COG2065	Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase	179
646765190	341	49.06	30	341	1	315	3.0e-104	371	COG0540	Aspartate carbamoyltransferase, catalytic chain	316
646765191	426	38.92	1	424	1	421	5.0e-102	365	COG0044	Dihydroorotase or related cyclic amidohydrolase	430
646765192	285	25.86	8	230	8	238	6.0e-25	108	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
646765194	308	31.49	16	307	2	306	5.0e-35	142	COG0451	Nucleoside-diphosphate-sugar epimerase	314
646765195	353	64	2	350	3	340	0.0e+00	560	COG1088	dTDP-D-glucose 4,6-dehydratase	340
646765196	297	58.39	3	288	1	283	6.0e-119	420	COG1209	dTDP-glucose pyrophosphorylase	286
646765197	183	61.71	4	178	2	173	9.0e-60	222	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase or related enzyme	173
646765198	308	49.3	10	293	3	274	2.0e-88	319	COG1091	dTDP-4-dehydrorhamnose reductase	281
646765199	471	44.41	2	334	1	333	1.0e-114	406	COG0836	Mannose-1-phosphate guanylyltransferase	333
646765200	272	31.15	16	272	5	263	2.0e-43	169	COG1682	ABC-type polysaccharide/polyol phosphate export permease	263
646765201	259	47.41	5	236	3	228	7.0e-75	273	COG1134	ABC-type polysaccharide/polyol phosphate transport system, ATPase component	249
646765202	460	22.19	56	428	17	394	1.0e-26	114	COG1541	Phenylacetate-coenzyme A ligase PaaK, adenylate-forming domain family	438
646765204	372	45.78	1	362	4	368	6.0e-105	374	COG0381	UDP-N-acetylglucosamine 2-epimerase	383
646765205	417	20.47	79	396	48	373	6.0e-13	68.9	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
646765206	377	28.35	1	377	1	380	6.0e-35	142	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
646765207	474	26.87	186	474	11	289	1.0e-31	131	COG0382	4-hydroxybenzoate polyprenyltransferase	289
646765208	438	18.71	7	424	25	442	1.0e-32	134	COG0277	FAD/FMN-containing dehydrogenase	459
646765209	246	23.9	1	245	6	256	2.0e-29	123	COG0300	Short-chain dehydrogenase	265
646765214	342	34.08	1	340	1	348	6.0e-52	198	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
646765216	328	21.81	39	324	85	377	2.0e-09	57	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
646765217	341	20.67	40	333	86	374	3.0e-10	60	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
646765218	196	29.57	1	180	3	186	3.0e-28	118	COG0406	Broad specificity phosphatase PhoE	208
646765221	1078	18.92	784	1076	114	381	2.0e-16	82.4	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
646765222	731	28.57	451	676	3	226	2.0e-24	107	COG1216	Glycosyltransferase, GT2 family	305
646765223	323	24.12	42	323	77	380	3.0e-16	79.3	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
646765224	319	33.33	5	319	3	312	3.0e-41	162	COG0451	Nucleoside-diphosphate-sugar epimerase	314
646765225	340	25.65	23	306	13	315	3.0e-28	119	COG0472	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase	319
646765226	626	44.54	14	614	3	584	0.0e+00	569	COG1086	NDP-sugar epimerase, includes UDP-GlcNAc-inverting 4,6-dehydratase FlaA1 and capsular polysaccharide biosynthesis protein EpsC	588
646765233	366	22.49	1	326	6	313	4.0e-33	135	COG0472	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase	319
646765234	521	35.71	134	514	3	408	4.0e-44	172	COG0840	Methyl-accepting chemotaxis protein	408
646765236	340	44.94	6	339	2	329	0.0e+00	470	COG1087	UDP-glucose 4-epimerase	329
646765237	382	23.24	22	379	18	379	8.0e-28	118	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
646765238	276	19.16	14	267	4	253	3.0e-06	46.3	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
646765239	420	21.95	14	419	7	414	3.0e-12	66.7	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
646765240	464	33.69	1	456	4	460	2.0e-97	350	COG1109	Phosphomannomutase	464
646765241	333	31.15	4	319	2	307	1.0e-53	203	COG0859	ADP-heptose:LPS heptosyltransferase	334
646765243	437	49.2	2	435	1	419	6.0e-125	441	COG1519	3-deoxy-D-manno-octulosonic-acid transferase	419
646765245	220	56.37	16	218	7	202	1.0e-65	243	COG0378	Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase	202
646765246	233	36.68	7	233	1	229	4.0e-41	161	COG0830	Urease accessory protein UreF	229
646765247	200	56.94	14	154	11	154	2.0e-34	139	COG2371	Urease accessory protein UreE	155
646765248	568	79.58	2	568	1	568	0.0e+00	1050	COG0804	Urease alpha subunit	568
646765249	101	69.31	1	101	1	101	5.0e-42	162	COG0832	Urease beta subunit	106
646765250	100	78.79	1	99	1	99	1.0e-43	167	COG0831	Urease gamma subunit	100
646765251	302	30.94	49	301	6	270	2.0e-33	136	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
646765252	289	37.27	17	287	6	269	1.0e-59	223	COG0829	Urease accessory protein UreH	269
646765255	230	52.89	1	222	3	227	1.0e-85	309	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
646765256	287	63.41	42	287	4	246	2.0e-101	362	COG4674	ABC-type uncharacterized transport system, ATPase component	249
646765257	401	31.95	65	398	8	314	6.0e-47	181	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
646765258	544	42.67	245	542	4	297	2.0e-65	243	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
646765259	432	30.53	24	396	1	364	1.0e-67	250	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
646765262	107	40	1	107	1	110	2.0e-19	87.7	COG0607	Rhodanese-related sulfurtransferase	110
646765263	217	41.75	6	211	1	206	4.0e-54	204	COG2518	Protein-L-isoaspartate O-methyltransferase	209
646765264	362	42.68	35	361	1	328	3.0e-85	308	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
646765265	495	48.37	5	493	9	499	0.0e+00	561	COG1129	ABC-type sugar transport system, ATPase component	500
646765266	337	42.11	16	337	3	310	7.0e-52	198	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
646765267	320	28.57	1	320	5	322	1.0e-36	147	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
646765268	349	22.33	7	324	1	274	2.0e-27	117	COG1082	Sugar phosphate isomerase/epimerase	274
646765269	383	33.16	4	381	2	341	1.0e-45	177	COG0673	Predicted dehydrogenase	342
646765273	254	31.78	1	254	3	252	3.0e-36	145	COG1192	Cellulose biosynthesis protein BcsQ	259
646765274	389	27.51	20	389	1	365	7.0e-42	164	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
646765275	313	31.1	1	297	1	293	3.0e-34	138	COG0583	DNA-binding transcriptional regulator, LysR family	297
646765276	559	37.46	1	550	1	510	0.0e+00	499	COG0155	Sulfite reductase, beta subunit (hemoprotein)	510
646765277	181	49.42	1	172	3	167	2.0e-44	172	COG3749	Uncharacterized conserved protein, DUF934 family	167
646765278	248	35.92	1	231	1	241	2.0e-50	192	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
646765279	320	32.4	8	320	4	261	5.0e-48	184	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
646765280	438	54.04	8	438	2	417	0.0e+00	555	COG2895	Sulfate adenylyltransferase subunit 1, EFTu-like GTPase family	431
646765281	252	44.96	1	237	3	238	2.0e-61	228	COG0007	Uroporphyrinogen-III methylase (siroheme synthase)	244
646765283	382	25.91	1	382	1	364	7.0e-43	168	COG0795	Lipopolysaccharide export LptBFGC system, permease protein LptF	364
646765284	365	27.09	1	345	2	359	4.0e-41	162	COG0795	Lipopolysaccharide export LptBFGC system, permease protein LptF	364
646765285	503	51.12	16	502	7	485	0.0e+00	540	COG0260	Leucyl aminopeptidase	485
646765286	138	34.31	1	132	1	137	6.0e-27	113	COG2927	DNA polymerase III, chi subunit	144
646765288	112	33.33	11	109	5	103	2.0e-11	61.3	COG4654	Cytochrome c551/c552	110
646765289	557	49.91	4	556	10	570	0.0e+00	707	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
646765290	328	36.5	6	327	1	297	5.0e-31	128	COG0583	DNA-binding transcriptional regulator, LysR family	297
646765291	301	46.05	1	297	5	284	3.0e-71	262	COG0682	Prolipoprotein diacylglyceryltransferase	287
646765292	241	29.54	9	240	5	235	8.0e-33	134	COG3471	Predicted secreted (periplasmic) protein	235
646765293	152	56.67	1	149	2	148	9.0e-54	202	COG2947	Predicted RNA-binding protein, contains PUA-like domain	156
646765295	104	34.02	4	100	2	98	7.0e-11	58.8	COG3027	Cell division protein ZapA, inhibits GTPase activity of FtsZ	105
646765297	643	34.21	45	642	9	608	7.0e-129	454	COG4206	Outer membrane cobalamin receptor protein	608
646765298	354	41.52	21	354	2	331	4.0e-46	178	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
646765299	284	41.98	11	272	1	258	5.0e-69	254	COG1120	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	258
646765300	353	39.07	13	353	10	338	5.0e-68	251	COG2038	NaMN:DMB phosphoribosyltransferase	347
646765301	258	32.68	7	258	2	245	1.0e-32	133	COG0368	Cobalamin synthase	246
646765302	196	29.74	1	191	3	196	2.0e-21	95.7	COG0406	Broad specificity phosphatase PhoE	208
646765303	316	31.97	22	304	21	312	7.0e-39	154	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
646765304	358	30.94	11	351	1	354	1.0e-48	187	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
646765305	313	43.49	5	307	1	315	6.0e-68	251	COG1270	Cobalamin biosynthesis protein CobD/CbiB	320
646765306	184	49.71	6	179	2	174	3.0e-52	197	COG2087	Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase	175
646765307	508	52.62	14	508	3	485	0.0e+00	591	COG1492	Cobyric acid synthase	486
646765308	139	32	16	139	15	138	8.0e-20	89.3	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
646765309	212	25.78	1	207	2	256	2.0e-20	92.9	COG1192	Cellulose biosynthesis protein BcsQ	259
646765310	128	58.4	2	126	1	124	3.0e-45	173	COG0853	Aspartate 1-decarboxylase	126
646765311	277	52.3	1	277	1	282	2.0e-97	349	COG0414	Panthothenate synthetase	285
646765312	303	43.51	67	299	1	239	3.0e-51	195	COG1354	Chromatin segregation and condensation protein Rec8/ScpA/Scc1, kleisin family	248
646765314	615	29.22	39	615	11	594	5.0e-85	309	COG0729	Outer membrane translocation and assembly module TamA	594
646765315	1455	22.42	330	1450	184	1278	4.0e-90	327	COG2911	Autotransporter translocation and assembly factor TamB	1278
646765316	711	40.39	16	566	4	558	0.0e+00	600	COG0143	Methionyl-tRNA synthetase	558
646765317	217	40.31	24	211	1	190	1.0e-33	136	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
646765318	362	42.75	49	313	10	265	7.0e-58	218	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
646765319	178	31.25	16	176	8	179	9.0e-18	83.1	COG2032	Cu/Zn superoxide dismutase	179
646765320	189	39.38	2	189	1	181	2.0e-58	218	COG0717	Deoxycytidine triphosphate deaminase	183
646765321	761	41.04	150	760	1	556	0.0e+00	602	COG1982	Arginine/lysine/ornithine decarboxylase	557
646765323	308	51.67	1	300	1	299	1.0e-105	376	COG3781	Predicted membrane chloride channel, bestrophin family	306
646765324	638	48.74	15	330	2	318	2.0e-98	353	COG0837	Glucokinase	320
646765325	261	31.16	25	234	1	204	1.0e-32	133	COG0363	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase	238
646765326	487	51.33	1	485	2	483	0.0e+00	617	COG0364	Glucose-6-phosphate 1-dehydrogenase	483
646765327	415	24.88	1	413	5	427	1.0e-29	124	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
646765328	312	36.01	26	309	8	292	9.0e-52	197	COG1175	ABC-type sugar transport system, permease component	295
646765329	285	34.74	1	284	3	281	1.0e-54	206	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
646765330	371	52.6	1	365	1	338	3.0e-118	418	COG3839	ABC-type sugar transport system, ATPase component	338
646765331	306	27.81	3	299	2	296	1.0e-34	140	COG0583	DNA-binding transcriptional regulator, LysR family	297
646765332	219	31.75	3	209	1	210	2.0e-25	109	COG0625	Glutathione S-transferase	211
646765333	255	44.44	73	241	11	178	2.0e-34	139	COG2840	DNA-nicking endonuclease, Smr domain	184
646765334	376	50.32	50	359	2	301	3.0e-92	332	COG0492	Thioredoxin reductase	305
646765336	243	31.39	21	241	2	208	4.0e-33	135	COG2834	Outer membrane lipoprotein-sorting protein	211
646765339	438	28.5	19	426	13	418	2.0e-38	153	COG1457	Purine-cytosine permease or related protein	442
646765340	437	55.4	2	430	5	436	0.0e+00	588	COG2256	Replication-associated recombination protein RarA (DNA-dependent ATPase)	436
646765341	431	56.88	1	430	1	429	0.0e+00	587	COG0172	Seryl-tRNA synthetase	429
646765344	261	51.37	1	253	1	254	8.0e-92	330	COG0024	Methionine aminopeptidase	255
646765346	277	34.69	9	275	1	218	5.0e-43	168	COG0850	Septum formation inhibitor MinC	219
646765347	271	65.43	1	269	1	268	3.0e-116	411	COG2894	Septum formation inhibitor-activating ATPase MinD	272
646765348	84	53.57	1	84	1	83	6.0e-22	95.7	COG0851	Septum formation topological specificity factor MinE	88
646765350	478	31.69	7	435	3	437	1.0e-49	191	COG0038	H+/Cl- antiporter ClcA	443
646765351	334	27.76	1	295	1	292	2.0e-51	196	COG0859	ADP-heptose:LPS heptosyltransferase	334
646765356	468	60.09	8	468	2	458	0.0e+00	619	COG0165	Argininosuccinate lyase	459
646765358	1072	48.83	140	1072	3	910	0.0e+00	1037	COG2352	Phosphoenolpyruvate carboxylase	910
646765359	332	53.23	10	318	1	307	1.0e-104	373	COG0181	Porphobilinogen deaminase	307
646765360	663	30	307	662	10	357	4.0e-50	193	COG2959	Uncharacterized conserved protein HemX (no evidence of involvement in heme biosynthesis)	391
646765361	396	31.55	3	391	1	389	2.0e-62	233	COG3071	Uncharacterized conserved protein HemY, contains two TPR repeats	400
646765362	349	31.15	19	277	5	260	4.0e-40	158	COG0300	Short-chain dehydrogenase	265
646765363	598	32.45	38	598	1	554	2.0e-97	349	COG0659	Sulfate permease or related transporter, MFS superfamily	554
646765366	1284	29.49	23	605	20	550	6.0e-96	346	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
646765369	508	44.33	21	500	1	469	0.0e+00	502	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
646765370	678	35.89	1	666	5	599	2.0e-120	426	COG3284	Transcriptional regulator of acetoin/glycerol metabolism	606
646765374	439	20.14	23	430	21	431	1.0e-23	104	COG2271	Sugar phosphate permease	448
646765375	252	40.78	1	250	1	250	2.0e-47	182	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
646765376	479	45.82	4	479	1	470	3.0e-130	458	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
646765377	175	55.43	1	175	1	171	9.0e-56	209	COG0221	Inorganic pyrophosphatase	171
646765378	697	18.33	32	696	1	662	3.0e-21	97.4	COG1289	Uncharacterized membrane protein YccC	674
646765379	105	42.86	1	77	3	79	6.0e-21	92.3	COG2827	Predicted endonuclease, GIY-YIG superfamily	95
646765380	389	49.23	1	388	1	384	2.0e-129	455	COG3146	Predicted N-acyltransferase	387
646765381	570	40.28	285	558	5	268	4.0e-68	252	COG0171	NH3-dependent NAD+ synthetase	268
646765382	112	74.11	1	112	1	112	8.0e-39	151	COG0347	Nitrogen regulatory protein PII	112
646765383	385	22.51	1	385	1	354	8.0e-33	135	COG3203	Outer membrane protein (porin)	354
646765384	259	74.3	7	255	6	253	7.0e-115	406	COG4598	ABC-type histidine transport system, ATPase component	256
646765385	237	55.26	7	234	1	228	2.0e-76	278	COG4160	ABC-type arginine/histidine transport system, permease component	228
646765386	229	53.91	1	227	1	230	3.0e-71	261	COG4215	ABC-type arginine transport system, permease component	230
646765387	258	31.66	4	256	15	269	3.0e-40	159	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
646765388	236	41.13	1	236	1	247	1.0e-48	186	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
646765390	241	48.48	5	234	3	229	2.0e-58	219	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
646765391	438	24.92	121	423	16	328	1.0e-33	137	COG0642	Signal transduction histidine kinase	336
646765394	583	41.62	58	582	1	523	0.0e+00	499	COG4986	ABC-type anion transport system, duplicated permease component	523
646765395	448	49.8	25	275	2	245	8.0e-84	304	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
646765399	105	31.58	11	105	9	103	3.0e-14	70.3	COG4575	Membrane-anchored ribosome-binding protein, inhibits growth in stationary phase, ElaB/YqjD/DUF883 family	104
646765401	466	46.84	1	450	4	460	0.0e+00	471	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
646765404	475	46.72	1	460	14	485	0.0e+00	510	COG0380	Trehalose-6-phosphate synthase	486
646765405	472	19.81	32	460	13	382	1.0e-14	74.9	COG2814	Predicted arabinose efflux permease, MFS family	394
646765406	167	38.92	1	167	20	174	9.0e-37	146	COG1881	Uncharacterized conserved protein, phosphatidylethanolamine-binding protein (PEBP) family	174
646765407	148	55.47	1	137	1	136	4.0e-42	163	COG3727	G:T-mismatch repair DNA endonuclease, very short patch repair protein	150
646765408	430	31.99	69	409	2	323	1.0e-60	227	COG0270	Site-specific DNA-cytosine methylase	328
646765412	235	31.28	21	226	2	200	3.0e-34	138	COG0625	Glutathione S-transferase	211
646765414	312	22.28	79	244	17	199	3.0e-10	59.5	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
646765416	63	50.94	10	62	1	53	5.0e-13	66.1	COG1773	Rubredoxin	55
646765418	644	44.75	1	536	1	529	0.0e+00	520	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
646765419	661	43.14	7	658	3	631	0.0e+00	737	COG0187	DNA gyrase/topoisomerase IV, subunit B	635
646765420	773	42.54	11	770	2	750	0.0e+00	736	COG0188	DNA gyrase/topoisomerase IV, subunit A	804
646765421	152	25.48	4	152	5	161	1.0e-12	66.1	COG5615	Uncharacterized membrane protein	161
646765422	402	23.78	12	195	1	184	5.0e-14	72.6	COG2059	Chromate transport protein ChrA	195
646765424	299	41.81	3	298	1	291	2.0e-63	235	COG0384	Predicted epimerase YddE/YHI9, PhzF superfamily	291
646765425	154	28.08	9	154	1	129	9.0e-15	73	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
646765426	398	43.56	14	396	68	455	3.0e-101	362	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
646765428	485	32.56	17	485	3	458	1.0e-92	333	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
646765429	632	60	1	627	2	618	0.0e+00	827	COG0326	Molecular chaperone, HSP90 family	623
646765430	238	30.68	10	183	5	169	1.0e-19	90.4	COG3161	4-hydroxybenzoate synthetase (chorismate-pyruvate lyase)	174
646765431	158	42.5	4	156	1	160	2.0e-35	141	COG3663	G:T/U-mismatch repair DNA glycosylase	169
646765433	133	23.15	24	129	18	125	3.0e-15	73.9	COG0662	Mannose-6-phosphate isomerase, cupin superfamily	127
646765434	275	29.06	159	274	11	127	3.0e-14	72.6	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
646765435	746	77.12	1	743	1	742	0.0e+00	1289	COG2838	Monomeric isocitrate dehydrogenase	744
646765436	311	20.31	61	299	18	270	5.0e-31	128	COG0421	Spermidine synthase	282
646765438	516	25.3	1	495	1	485	6.0e-42	165	COG0591	Na+/proline symporter	493
646765440	139	38.97	3	138	2	133	3.0e-29	120	COG2764	Uncharacterized conserved protein PhnB, glyoxalase superfamily	136
646765441	317	37.26	5	314	1	238	5.0e-62	231	COG0176	Transaldolase	239
646765442	406	56.05	26	405	19	398	1.0e-99	356	COG3135	Predicted benzoate:H+ symporter BenE	402
646765443	391	66.58	1	391	1	392	0.0e+00	563	COG3825	Uncharacterized conserved protein,  contains von Willebrand factor type A (vWA) domain	393
646765444	280	24	1	265	18	278	2.0e-36	146	COG0714	MoxR-like ATPase	329
646765445	122	44.44	7	122	2	110	7.0e-17	79.3	COG2863	Cytochrome c553	121
646765446	126	41.51	13	118	3	100	5.0e-14	70	COG2863	Cytochrome c553	121
646765448	214	54.07	1	209	1	209	2.0e-81	295	COG0177	Endonuclease III	211
646765449	301	57.05	3	148	32	180	1.0e-46	180	COG2878	Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit	198
646765450	210	27.22	1	179	1	180	3.0e-10	58.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
646765451	425	54.63	1	420	1	415	0.0e+00	596	COG4553	Poly-beta-hydroxyalkanoate depolymerase	415
646765452	629	33.39	1	594	12	609	4.0e-110	392	COG3387	Glucoamylase (glucan-1,4-alpha-glucosidase), GH15 family	612
646765455	439	41.26	74	436	3	345	2.0e-87	316	COG2706	6-phosphogluconolactonase, cycloisomerase 2 family	346
646765456	1358	37.37	704	1354	228	854	0.0e+00	484	COG1674	DNA segregation ATPase FtsK/SpoIIIE and related proteins	858
646765458	404	65.32	6	399	3	391	0.0e+00	570	COG0027	Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase)	394
646765460	127	33.04	11	125	2	111	8.0e-14	69.3	COG3895	Membrane-bound inhibitor of C-type lysozyme	112
646765461	550	37.96	1	535	2	535	0.0e+00	499	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
646765462	478	40.43	6	470	1	463	8.0e-107	381	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
646765463	484	41.54	4	465	22	482	1.0e-118	420	COG0513	Superfamily II DNA and RNA helicase	513
646765465	287	40.57	1	278	3	273	1.0e-82	299	COG1054	Predicted sulfurtransferase	308
646765466	1196	48.75	7	1119	2	1111	0.0e+00	1287	COG0587	DNA polymerase III, alpha subunit	1139
646765467	253	20	8	253	7	263	4.0e-11	62.1	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
646765468	587	38.43	11	584	2	567	5.0e-130	458	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
646765470	341	19.87	18	319	2	291	8.0e-15	74.8	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
646765471	364	19.35	27	363	15	376	2.0e-12	67.4	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
646765472	433	17.11	4	414	24	423	1.0e-11	64.8	COG3307	O-antigen ligase	424
646765473	281	25.22	1	220	4	227	5.0e-15	75.2	COG1216	Glycosyltransferase, GT2 family	305
646765475	186	31.75	57	182	7	131	1.0e-13	69.6	COG5485	Predicted ester cyclase	131
646765476	310	44.67	1	297	1	300	2.0e-101	362	COG2974	DNA recombination-dependent growth factor C	303
646765477	224	32.66	4	216	81	319	2.0e-28	119	COG3712	Periplasmic ferric-dicitrate binding protein FerR, regulates iron transport through sigma-19	322
646765479	157	50.65	1	150	3	151	2.0e-44	171	COG3865	Glyoxalase superfamily enzyme, possibly 3-demethylubiquinone-9 3-methyltransferase	151
646765480	161	46.72	15	140	1	134	2.0e-34	138	COG2764	Uncharacterized conserved protein PhnB, glyoxalase superfamily	136
646765482	141	44.93	1	69	1	69	1.0e-10	58.8	COG3585	Molybdopterin-binding protein	69
646765484	166	59.33	11	160	11	159	3.0e-57	214	COG1956	GAF domain-containing protein, putative methionine-R-sulfoxide reductase	163
646765486	137	17.73	4	127	3	138	2.0e-06	45.2	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
646765488	489	46.63	3	489	2	483	0.0e+00	502	COG1530	Ribonuclease G or E	487
646765489	209	44.9	8	203	1	185	1.0e-48	186	COG0424	Predicted house-cleaning NTP pyrophosphatase, Maf/HAM1 superfamily	193
646765490	156	49.03	1	155	1	155	3.0e-55	207	COG1576	23S rRNA pseudoU1915 N3-methylase RlmH	155
646765491	149	48.62	1	109	1	109	1.0e-31	129	COG0799	Ribosomal silencing factor RsfS, regulates association of 30S and 50S subunits	115
646765492	251	29.57	22	249	2	195	4.0e-40	158	COG1057	Nicotinic acid mononucleotide adenylyltransferase	197
646765493	307	61.59	7	307	6	303	3.0e-124	438	COG0408	Coproporphyrinogen III oxidase	303
646765494	427	59.35	1	424	1	427	0.0e+00	590	COG0151	Phosphoribosylamine-glycine ligase	428
646765495	242	62.92	1	239	1	239	7.0e-98	350	COG0217	Transcriptional and/or translational regulatory protein YebC/TACO1	241
646765497	216	55.45	7	215	1	210	1.0e-74	273	COG0035	Uracil phosphoribosyltransferase	210
646765498	259	36.15	3	253	1	249	1.0e-33	137	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
646765499	129	53.72	1	121	3	123	4.0e-46	176	COG1803	Methylglyoxal synthase	142
646765500	324	46.65	2	324	1	326	1.0e-77	283	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
646765503	601	57.34	6	597	5	560	0.0e+00	683	COG2060	K+-transporting ATPase, A chain	560
646765504	707	70.78	4	707	1	681	0.0e+00	1031	COG2216	High-affinity K+ transport system, ATPase chain B	681
646765505	192	57.37	1	189	1	190	4.0e-67	247	COG2156	K+-transporting ATPase, c chain	190
646765506	951	49.19	2	924	4	887	0.0e+00	907	COG2205	K+-sensing histidine kinase KdpD	890
646765507	232	46.05	8	232	3	229	9.0e-57	213	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
646765508	106	49.52	1	105	2	106	5.0e-18	82.8	COG2076	Multidrug transporter EmrE and related cation transporters	106
646765510	864	36.73	29	864	3	829	0.0e+00	588	COG3127	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component	829
646765511	137	39.23	7	136	1	127	1.0e-30	125	COG2346	Truncated hemoglobin YjbI	133
646765512	214	53.72	24	211	7	181	2.0e-46	179	COG3803	Uncharacterized conserved protein, DUF924 family	182
646765513	655	21.3	58	559	1	448	2.0e-22	100	COG1807	4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferase of PMT family	535
646765514	248	42.91	1	248	4	250	6.0e-40	157	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
646765515	195	35.6	1	187	14	203	2.0e-42	165	COG1611	Predicted Rossmann fold nucleotide-binding protein	205
646765516	241	22.42	1	163	5	168	7.0e-12	64.3	COG1309	DNA-binding transcriptional regulator, AcrR family	201
646765517	228	44.54	100	218	1	119	3.0e-35	141	COG0818	Diacylglycerol kinase	123
646765518	347	27.18	5	337	1	379	1.0e-30	127	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
646765519	313	36.51	62	299	1	237	3.0e-64	238	COG2908	UDP-2,3-diacylglucosamine pyrophosphatase LpxH	237
646765520	174	26.54	12	171	10	171	7.0e-06	44	COG1714	Uncharacterized membrane protein YckC, RDD family	172
646765523	187	24.6	1	186	11	181	1.0e-15	76.7	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
646765524	587	50.89	23	580	4	549	0.0e+00	677	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
646765525	163	55.9	1	161	3	163	9.0e-48	182	COG0440	Acetolactate synthase, small subunit	163
646765526	338	67.86	1	336	3	338	0.0e+00	537	COG0059	Ketol-acid reductoisomerase	338
646765527	212	41.74	1	211	21	236	7.0e-52	197	COG0688	Phosphatidylserine decarboxylase	239
646765528	289	39.3	44	270	4	226	3.0e-49	188	COG1183	Phosphatidylserine synthase	234
646765529	515	50.36	3	417	1	409	3.0e-123	435	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
646765530	520	30.6	8	496	19	509	3.0e-66	246	COG0659	Sulfate permease or related transporter, MFS superfamily	554
646765531	211	41.12	1	193	1	197	1.0e-50	193	COG0288	Carbonic anhydrase	207
646765533	435	25.07	43	408	10	366	3.0e-37	149	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
646765534	90	60.23	3	90	2	89	4.0e-26	109	COG0184	Ribosomal protein S15P/S13E	89
646765535	711	64.18	3	700	1	691	0.0e+00	995	COG1185	Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase)	692
646765536	338	42.9	1	333	1	325	5.0e-72	264	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
646765537	258	51.59	6	255	2	251	1.0e-74	273	COG0149	Triosephosphate isomerase	251
646765538	131	56.76	6	79	3	75	2.0e-13	67.9	COG1314	Preprotein translocase subunit SecG	86
646765540	133	52.14	17	133	5	121	1.0e-32	132	COG0838	NADH:ubiquinone oxidoreductase subunit 3 (chain A)	123
646765541	159	69.23	3	158	13	168	7.0e-76	276	COG0377	NADH:ubiquinone oxidoreductase 20 kD subunit (chhain B) or related Fe-S oxidoreductase	194
646765542	200	49.15	4	180	5	171	8.0e-46	177	COG0852	NADH:ubiquinone oxidoreductase 27 kD subunit (chain C)	176
646765543	417	59.23	1	417	9	398	0.0e+00	611	COG0649	NADH:ubiquinone oxidoreductase 49 kD subunit (chain D)	398
646765544	161	45.28	1	159	4	156	6.0e-47	180	COG1905	NADH:ubiquinone oxidoreductase 24 kD subunit (chain E)	160
646765545	441	58.49	1	423	2	423	0.0e+00	637	COG1894	NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F)	424
646765546	777	39.06	1	735	1	692	0.0e+00	620	COG1034	NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)	693
646765547	354	48.96	16	351	6	332	7.0e-94	337	COG1005	NADH:ubiquinone oxidoreductase subunit 1 (chain H)	332
646765548	162	43.9	4	162	3	161	2.0e-41	161	COG1143	Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)	172
646765549	230	37.93	1	174	1	166	2.0e-23	102	COG0839	NADH:ubiquinone oxidoreductase subunit 6 (chain J)	166
646765550	101	61.39	1	101	1	100	1.0e-21	94.4	COG0713	NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K)	100
646765551	688	42.43	10	681	1	606	0.0e+00	501	COG1009	NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit	606
646765552	496	54.14	4	496	3	495	0.0e+00	536	COG1008	NADH:ubiquinone oxidoreductase subunit 4 (chain M)	497
646765553	490	41.94	6	488	5	475	3.0e-95	342	COG1007	NADH:ubiquinone oxidoreductase subunit 2 (chain N)	475
646765558	141	45.26	1	133	1	137	7.0e-40	156	COG5319	Uncharacterized protein	142
646765559	398	33.5	1	398	1	389	2.0e-68	253	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
646765560	375	27.79	1	365	1	383	3.0e-36	146	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
646765561	152	40.14	5	148	17	159	6.0e-26	110	COG2030	Acyl dehydratase	159
646765562	158	34.29	19	158	20	158	8.0e-29	119	COG2030	Acyl dehydratase	159
646765563	233	37.27	1	214	1	211	3.0e-38	151	COG0625	Glutathione S-transferase	211
646765564	419	34.48	1	403	1	390	2.0e-70	260	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
646765565	368	39.22	24	354	1	317	3.0e-67	249	COG3173	Predicted  kinase, aminoglycoside phosphotransferase (APT) family	321
646765566	238	25.71	8	215	1	206	2.0e-24	106	COG0406	Broad specificity phosphatase PhoE	208
646765567	262	38.21	14	258	13	255	8.0e-44	170	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
646765568	518	42.81	6	290	1	285	3.0e-87	316	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
646765569	215	26.15	2	211	1	211	6.0e-21	94.5	COG0625	Glutathione S-transferase	211
646765570	390	36.39	28	390	21	388	6.0e-84	304	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
646765571	168	27.03	11	155	1	137	9.0e-12	63.4	COG1569	Predicted nucleic acid-binding protein, contains PIN domain	142
646765572	260	58.69	1	259	1	253	9.0e-88	316	COG3022	Cytoplasmic iron level regulating protein YaaA, DUF328/UPF0246 family	253
646765573	388	36.46	9	381	4	365	6.0e-63	234	COG2866	Murein tripeptide amidase MpaA	374
646765575	240	27.23	32	233	15	214	1.0e-20	93.5	COG3235	Uncharacterized membrane protein	223
646765576	293	28.05	1	217	1	210	4.0e-31	128	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
646765578	371	26.06	6	357	12	355	4.0e-30	126	COG0628	Predicted PurR-regulated permease PerM	355
646765586	315	27.35	61	291	71	281	2.0e-11	63.7	COG4974	Site-specific recombinase XerD	300
646765587	307	29.53	3	296	2	278	1.0e-40	160	COG1091	dTDP-4-dehydrorhamnose reductase	281
646765588	67	43.48	1	66	2	70	2.0e-10	57.7	COG2608	Copper chaperone CopZ	71
646765589	140	32.5	1	119	1	120	2.0e-21	94.8	COG0789	DNA-binding transcriptional regulator, MerR family	124
646765592	346	28.45	6	342	2	329	3.0e-34	139	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
646765593	281	49.28	2	279	1	276	8.0e-96	343	COG2961	23S rRNA A2030 N6-methylase RlmJ	279
646765594	323	40.49	1	323	1	313	3.0e-73	268	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
646765595	265	36.26	7	262	2	250	5.0e-41	161	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
646765596	410	21.79	29	382	1	297	2.0e-34	140	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
646765597	399	60.35	3	398	1	396	0.0e+00	592	COG1448	Aspartate/tyrosine/aromatic aminotransferase	396
646765598	697	65.47	22	686	1	661	0.0e+00	1090	COG0556	Excinuclease UvrABC helicase subunit UvrB	663
646765599	182	49.45	1	178	1	179	7.0e-55	206	COG3470	Uncharacterized protein probably involved in high-affinity Fe2+ transport	179
646765601	281	25.43	3	265	9	296	4.0e-25	108	COG0672	High-affinity Fe2+/Pb2+ permease	383
646765603	86	40	32	86	9	63	2.0e-06	44.2	COG4256	Hemin uptake protein HemP	63
646765605	132	27.13	10	132	9	136	8.0e-21	92.8	COG1765	Uncharacterized OsmC-related protein	137
646765606	292	42.61	1	288	1	276	5.0e-60	224	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
646765607	335	31.77	6	299	1	291	1.0e-40	160	COG0583	DNA-binding transcriptional regulator, LysR family	297
646765609	139	39.71	3	138	1	136	8.0e-31	126	COG0848	Biopolymer transport protein ExbD	137
646765610	243	34.84	9	228	1	216	2.0e-39	155	COG0811	Biopolymer transport protein ExbB/TolQ	216
646765611	247	30.22	64	245	67	243	1.0e-09	57.1	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
646765612	85	42.86	1	49	1	49	6.0e-07	45.7	COG2906	Bacterioferritin-associated ferredoxin	63
646765613	295	44.61	17	284	2	269	2.0e-73	269	COG0796	Glutamate racemase	269
646765614	159	65.38	1	156	1	156	6.0e-57	213	COG2193	Bacterioferritin (cytochrome b1)	157
646765615	507	48.69	1	303	2	297	3.0e-104	372	COG1951	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain	297
646765616	189	43.56	4	166	8	169	1.0e-39	156	COG2862	Uncharacterized membrane protein YqhA	169
646765617	300	27.05	6	297	15	289	4.0e-10	59.1	COG5006	Threonine/homoserine efflux transporter RhtA	292
646765618	660	45.55	74	646	1	528	0.0e+00	638	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
646765619	142	31.91	28	121	9	100	2.0e-12	65.4	COG4327	Uncharacterized membrane protein	101
646765623	666	28.76	221	525	47	335	2.0e-31	131	COG0642	Signal transduction histidine kinase	336
646765624	231	27.23	8	220	2	208	5.0e-32	131	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
646765625	128	46.53	3	103	2	102	1.0e-24	105	COG1320	Multisubunit Na+/H+ antiporter, MnhG subunit	113
646765626	91	48.86	1	88	2	89	3.0e-10	56.7	COG2212	Multisubunit Na+/H+ antiporter, MnhF subunit	89
646765627	165	34.81	6	163	1	157	2.0e-25	108	COG1863	Multisubunit Na+/H+ antiporter, MnhE subunit	158
646765629	110	43.86	1	110	1	114	6.0e-21	92.6	COG1006	Multisubunit Na+/H+ antiporter, MnhC subunit	115
646765630	933	38.68	3	623	1	606	7.0e-113	402	COG1009	NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit	606
646765632	361	36.96	1	349	1	332	3.0e-61	229	COG4448	L-asparaginase II	339
646765633	330	33.72	7	173	1	160	3.0e-30	125	COG0835	Chemotaxis signal transduction protein	165
646765635	579	33.58	30	285	8	272	2.0e-10	61.5	COG0457	Tetratricopeptide (TPR) repeat	291
646765636	341	43.47	1	325	1	314	2.0e-83	302	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
646765637	247	45.34	8	247	6	251	8.0e-47	180	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
646765638	296	33.55	3	296	2	295	1.0e-34	140	COG0583	DNA-binding transcriptional regulator, LysR family	297
646765639	519	26.89	257	493	3	230	3.0e-46	180	COG1794	Aspartate/glutamate racemase	230
646765640	1982	42.06	24	1007	1	932	0.0e+00	1123	COG0178	Excinuclease UvrABC ATPase subunit	935
646765641	330	29.85	22	325	7	323	5.0e-38	151	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
646765642	183	55.68	3	178	1	173	2.0e-49	188	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase or related enzyme	173
646765644	141	47.06	15	133	1	119	8.0e-28	116	COG0818	Diacylglycerol kinase	123
646765646	431	43.27	72	412	20	350	4.0e-65	242	COG3405	Endo-1,4-beta-D-glucanase Y	360
646765650	261	25.9	1	243	2	250	7.0e-19	87.9	COG1192	Cellulose biosynthesis protein BcsQ	259
646765651	843	25.54	231	689	13	436	2.0e-49	191	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
646765654	209	39.02	2	206	1	197	6.0e-42	164	COG1279	Arginine exporter protein ArgO	202
646765655	297	20.67	2	294	1	293	2.0e-17	83.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
646765656	316	31	1	299	1	296	5.0e-31	128	COG0583	DNA-binding transcriptional regulator, LysR family	297
646765657	390	49.09	11	389	8	389	2.0e-121	429	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
646765658	463	19.75	94	417	63	351	6.0e-08	52.5	COG2814	Predicted arabinose efflux permease, MFS family	394
646765661	113	69.03	1	113	1	112	2.0e-35	140	COG5605	Cytochrome c oxidase subunit IV	115
646765662	235	36.82	16	235	5	206	8.0e-39	153	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
646765663	203	30.73	21	188	32	208	3.0e-24	105	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
646765664	586	49.72	8	535	1	511	0.0e+00	543	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
646765665	381	24	3	272	1	240	5.0e-47	182	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
646765667	421	21.11	43	402	46	394	1.0e-07	51.4	COG2814	Predicted arabinose efflux permease, MFS family	394
646765669	465	43.08	24	463	2	436	2.0e-96	346	COG2252	Xanthine/uracil/vitamin C permease, AzgA family	436
646765670	248	58.23	4	240	9	244	1.0e-85	309	COG4312	Predicted dithiol-disulfide oxidoreductase, DUF899 family	247
646765672	304	26.13	1	288	1	297	2.0e-22	99.7	COG0451	Nucleoside-diphosphate-sugar epimerase	314
646765673	307	35.29	6	306	4	292	4.0e-31	128	COG0583	DNA-binding transcriptional regulator, LysR family	297
646765674	506	62.55	1	494	4	496	0.0e+00	627	COG2986	Histidine ammonia-lyase	498
646765675	231	36.05	1	231	4	236	3.0e-54	205	COG2188	DNA-binding transcriptional regulator, GntR family	236
646765676	562	72.84	6	561	1	556	0.0e+00	953	COG2987	Urocanate hydratase	561
646765677	209	35.92	1	206	1	191	3.0e-30	125	COG3758	Various environmental stresses-induced protein Ves (function unknown)	193
646765678	409	41.04	23	404	28	404	2.0e-91	330	COG1228	Imidazolonepropionase or related amidohydrolase	406
646765679	461	27.75	29	442	28	413	6.0e-48	185	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
646765680	270	48.28	6	264	5	264	7.0e-74	270	COG3741	N-formylglutamate amidohydrolase	272
646765684	383	36.07	24	381	3	364	1.0e-53	204	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
646765686	288	48.21	3	282	1	277	6.0e-82	297	COG2240	Pyridoxal/pyridoxine/pyridoxamine kinase	281
646765687	486	49.79	4	486	2	479	0.0e+00	515	COG0297	Glycogen synthase	487
646765688	421	50.37	10	418	2	388	0.0e+00	515	COG0448	ADP-glucose pyrophosphorylase	393
646765689	432	25.34	114	397	9	282	1.0e-21	98.2	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
646765694	305	33.22	10	302	3	291	2.0e-34	139	COG0583	DNA-binding transcriptional regulator, LysR family	297
646765696	263	34.96	3	259	1	251	2.0e-37	149	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
646765697	331	24.25	9	324	2	332	1.0e-39	157	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
646765698	533	34.55	128	236	1	109	1.0e-11	64.9	COG0607	Rhodanese-related sulfurtransferase	110
646765700	317	37.14	1	302	3	280	9.0e-48	184	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
646765701	229	54.35	1	227	1	230	4.0e-68	251	COG4215	ABC-type arginine transport system, permease component	230
646765702	237	57.71	7	233	1	227	2.0e-74	272	COG4160	ABC-type arginine/histidine transport system, permease component	228
646765703	263	71.71	9	259	4	253	2.0e-115	408	COG4598	ABC-type histidine transport system, ATPase component	256
646765704	347	42.38	1	327	1	328	2.0e-77	282	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
646765705	411	53.12	7	406	9	404	0.0e+00	509	COG4992	Acetylornithine/succinyldiaminopimelate/putrescine aminotransferase	404
646765706	350	41.72	1	338	1	336	3.0e-85	308	COG3138	Arginine/ornithine N-succinyltransferase beta subunit	336
646765707	345	49.41	1	340	1	336	1.0e-105	376	COG3138	Arginine/ornithine N-succinyltransferase beta subunit	336
646765708	487	38.13	4	459	3	455	2.0e-103	370	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
646765709	447	63.45	2	447	1	441	0.0e+00	611	COG3724	Succinylarginine dihydrolase	442
646765710	352	44.67	8	345	1	323	2.0e-83	302	COG2988	Succinylglutamate desuccinylase	324
646765711	264	33.97	8	264	12	270	2.0e-37	149	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
646765712	458	26.37	25	442	6	399	2.0e-47	183	COG3434	c-di-GMP-related signal transduction protein, contains EAL and HDOD domains	407
646765715	433	33.97	24	388	2	364	3.0e-65	242	COG3434	c-di-GMP-related signal transduction protein, contains EAL and HDOD domains	407
646765716	201	38.27	40	196	1	157	2.0e-33	135	COG1225	Peroxiredoxin	157
646765718	1110	37.77	2	777	1	774	0.0e+00	707	COG0841	Multidrug efflux pump subunit AcrB	1009
646765719	1044	38.33	2	1018	1	1009	0.0e+00	928	COG0841	Multidrug efflux pump subunit AcrB	1009
646765720	459	34.02	92	428	38	372	7.0e-34	138	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
646765721	281	32.26	28	273	1	246	2.0e-38	152	COG1414	DNA-binding transcriptional regulator, IclR family	246
646765723	222	54.31	20	216	6	201	6.0e-59	220	COG4566	Two-component response regulator, FixJ family, consists of REC and HTH domains	202
646765725	232	50.51	20	217	5	202	5.0e-61	227	COG4566	Two-component response regulator, FixJ family, consists of REC and HTH domains	202
646765727	341	23.71	49	337	3	277	5.0e-19	88.6	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
646765730	467	33.19	1	454	1	465	4.0e-76	279	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
646765731	474	41.44	8	473	4	469	4.0e-116	412	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
646765732	154	26.21	9	153	1	128	4.0e-11	61.1	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
646765733	126	40.48	1	125	1	126	3.0e-19	87.5	COG0239	Fluoride ion exporter CrcB/FEX, affects chromosome condensation	126
646765734	395	34.78	7	395	3	404	3.0e-76	278	COG0004	Ammonia channel protein AmtB	409
646765737	529	58.5	110	256	5	151	4.0e-47	183	COG5616	TolB amino-terminal domain (function unknown)	152
646765738	251	27.97	1	244	1	259	8.0e-18	84.2	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
646765740	132	23.97	13	132	12	130	2.0e-07	48.3	COG1917	Cupin domain protein related to quercetin dioxygenase	131
646765741	285	46.67	10	186	6	184	9.0e-42	164	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
646765743	149	30.67	1	144	1	150	1.0e-23	102	COG1959	DNA-binding transcriptional regulator, IscR family	150
646765744	215	47.17	5	215	1	211	5.0e-58	217	COG2910	Putative NADH-flavin reductase	211
646765745	934	26.92	508	816	1	306	4.0e-36	147	COG0668	Small-conductance mechanosensitive channel	316
646765746	222	25.48	43	199	6	156	1.0e-09	56.6	COG5553	Predicted metal-dependent enzyme of the double-stranded beta helix superfamily	191
646765747	157	40.79	1	151	4	154	1.0e-33	135	COG1522	DNA-binding transcriptional regulator, Lrp family	154
646765749	838	19.43	8	564	3	523	1.0e-30	128	COG1289	Uncharacterized membrane protein YccC	674
646765750	1130	30.18	1	1123	1	1069	0.0e+00	533	COG1330	Exonuclease V gamma subunit	1078
646765751	1243	30.33	11	1205	4	1139	0.0e+00	562	COG1074	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)	1139
646765752	696	26.76	67	695	81	696	2.0e-69	257	COG0507	ATP-dependent exoDNAse (exonuclease V), alpha subunit, helicase superfamily I	696
646765755	431	31.11	32	253	17	239	5.0e-39	155	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
646765756	96	42.35	1	85	1	85	1.0e-14	71.2	COG1359	Quinol monooxygenase YgiN	100
646765759	262	26.16	25	256	3	221	4.0e-15	75.2	COG1434	Uncharacterized SAM-binding protein YcdF, DUF218 family	223
646765764	300	34.59	4	291	2	289	1.0e-35	143	COG0583	DNA-binding transcriptional regulator, LysR family	297
646765765	419	41.44	35	401	26	390	2.0e-87	316	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
646765766	350	47.49	1	178	4	180	4.0e-46	178	COG1386	Chromosome segregation and condensation protein ScpB	184
646765767	589	45.02	196	439	1	248	2.0e-66	247	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
646765768	152	44.3	1	144	8	152	6.0e-32	129	COG0779	Ribosome maturation factor RimP	153
646765769	491	53.06	159	353	1	190	2.0e-48	186	COG0195	Transcription antitermination factor NusA, contains S1 and KH domains	190
646765770	975	65.94	475	975	3	507	0.0e+00	683	COG0532	Translation initiation factor IF-2, a GTPase	509
646765771	121	41.59	10	118	6	118	4.0e-25	106	COG0858	Ribosome-binding factor A	118
646765772	311	41.25	6	308	6	271	1.0e-72	266	COG0130	tRNA U55 pseudouridine synthase TruB, may also work on U342 of tmRNA	271
646765774	413	49.56	13	350	6	344	6.0e-89	321	COG1566	Multidrug resistance efflux pump	352
646765775	506	30.75	23	487	1	456	6.0e-56	212	COG1538	Outer membrane protein TolC	457
646765776	171	34.13	27	152	1	123	6.0e-16	77.3	COG1846	DNA-binding transcriptional regulator, MarR family	126
646765777	609	67.27	1	605	1	603	0.0e+00	982	COG1217	Predicted membrane GTPase involved in stress response	603
646765778	953	59.11	2	945	1	906	0.0e+00	1334	COG0567	2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes	906
646765779	422	54.27	2	421	1	404	7.0e-112	397	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
646765780	476	47.75	1	466	1	454	0.0e+00	517	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
646765781	365	52.37	1	358	9	367	0.0e+00	463	COG1485	Predicted ATPase	367
646765782	152	28.57	6	108	5	108	3.0e-07	48.2	COG3293	Transposase	124
646765783	161	23.66	32	161	33	162	5.0e-14	70.8	COG4731	Uncharacterized conserved protein, DUF2147 family	162
646765787	157	51.79	9	64	8	63	7.0e-15	73.4	COG1923	sRNA-binding regulator protein Hfq	77
646765789	186	43.48	1	155	15	175	5.0e-27	114	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
646765790	302	34.43	19	289	11	252	9.0e-21	94.4	COG5662	Transmembrane transcriptional regulator (anti-sigma factor RsiW)	256
646765791	525	22.87	22	511	3	455	2.0e-24	107	COG0277	FAD/FMN-containing dehydrogenase	459
646765794	606	38.75	50	600	1	529	0.0e+00	462	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
646765795	433	32.49	9	433	2	391	1.0e-59	224	COG0183	Acetyl-CoA acetyltransferase	392
646765797	473	39.76	233	467	3	248	2.0e-35	144	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
646765798	832	26.54	142	510	28	382	2.0e-44	174	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
646765799	263	23.16	1	190	1	185	2.0e-06	46.6	COG1309	DNA-binding transcriptional regulator, AcrR family	201
646765800	417	23.39	24	390	28	391	1.0e-25	111	COG2814	Predicted arabinose efflux permease, MFS family	394
646765801	300	29.03	11	285	9	284	1.0e-25	110	COG1295	Uncharacterized membrane protein, BrkB/YihY/UPF0761 family (not an RNase)	303
646765807	329	28.19	2	329	1	334	5.0e-39	155	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
646765808	560	34.83	155	420	85	336	7.0e-35	142	COG0642	Signal transduction histidine kinase	336
646765811	254	45.63	3	248	2	249	1.0e-40	159	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
646765812	302	33.33	3	299	2	297	3.0e-39	155	COG0583	DNA-binding transcriptional regulator, LysR family	297
646765814	142	42.4	1	123	1	123	1.0e-34	138	COG3795	Uncharacterized conserved protein	123
646765818	142	29.75	8	127	12	129	3.0e-08	51.1	COG4319	Ketosteroid isomerase homolog	137
646765819	134	38.1	8	132	6	129	5.0e-22	96.6	COG3791	Uncharacterized conserved protein	133
646765820	333	28.18	35	332	29	355	7.0e-31	128	COG4188	Predicted dienelactone hydrolase	365
646765821	370	21.87	19	360	16	349	4.0e-20	92.7	COG0628	Predicted PurR-regulated permease PerM	355
646765822	516	32.5	46	483	22	456	5.0e-54	205	COG1538	Outer membrane protein TolC	457
646765823	377	34.27	31	349	22	336	1.0e-52	200	COG1566	Multidrug resistance efflux pump	352
646765826	896	52.24	86	887	2	785	0.0e+00	892	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
646765827	155	59.84	34	155	35	156	1.0e-46	179	COG4875	Uncharacterized protein	156
646765828	698	42.86	15	698	12	693	0.0e+00	641	COG1523	Pullulanase/glycogen debranching enzyme	697
646765829	831	47.1	20	824	4	750	0.0e+00	830	COG0058	Glucan phosphorylase	750
646765831	319	24.29	143	316	44	206	1.0e-08	54.2	COG2135	Putative SOS response-associated peptidase YedK	226
646765832	1049	37.07	9	1048	2	1073	0.0e+00	1002	COG0587	DNA polymerase III, alpha subunit	1139
646765833	489	22.31	77	448	13	354	1.0e-07	51.5	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
646765835	135	22.73	4	134	3	126	2.0e-15	75.1	COG3791	Uncharacterized conserved protein	133
646765836	327	31.33	10	306	1	296	8.0e-40	157	COG0583	DNA-binding transcriptional regulator, LysR family	297
646765837	435	43.55	5	410	3	405	6.0e-85	308	COG1301	Na+/H+-dicarboxylate symporter	415
646765838	262	25	3	255	4	253	2.0e-23	102	COG0725	ABC-type molybdate transport system, periplasmic component	258
646765839	431	21.08	3	428	1	394	2.0e-11	63.7	COG2814	Predicted arabinose efflux permease, MFS family	394
646765840	899	29.6	23	291	6	267	2.0e-29	125	COG0074	Succinyl-CoA synthetase, alpha subunit	293
646765841	136	32.06	6	136	5	132	1.0e-20	92.4	COG3791	Uncharacterized conserved protein	133
646765843	421	15.3	1	266	4	274	4.0e-07	49.6	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
646765844	575	25.92	5	572	105	752	1.0e-75	277	COG4993	Glucose dehydrogenase	773
646765845	660	37.46	20	648	25	599	9.0e-127	447	COG3284	Transcriptional regulator of acetoin/glycerol metabolism	606
646765847	249	37.4	3	247	2	251	4.0e-40	158	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
646765848	305	27.65	2	290	1	289	4.0e-24	105	COG0583	DNA-binding transcriptional regulator, LysR family	297
646765849	280	33.87	150	273	1	124	2.0e-21	96.5	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
646765850	125	25.56	28	115	18	107	3.0e-10	57.7	COG0662	Mannose-6-phosphate isomerase, cupin superfamily	127
646765851	248	32.53	1	233	4	250	5.0e-24	104	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
646765852	275	34.22	1	242	1	248	5.0e-29	121	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
646765854	1445	38.56	949	1392	26	466	2.0e-72	268	COG2319	WD40 repeat	466
646765855	286	21.96	101	284	23	233	9.0e-08	51	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
646765858	831	47.5	17	750	3	704	0.0e+00	717	COG0557	Exoribonuclease R	706
646765859	247	45.45	6	246	23	260	6.0e-58	217	COG0566	tRNA G18 (ribose-2'-O)-methylase SpoU	260
646765864	231	51.08	1	227	1	226	9.0e-70	256	COG0120	Ribose 5-phosphate isomerase	227
646765865	409	23.41	1	368	1	379	2.0e-21	97.4	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
646765866	184	34.26	70	176	5	111	1.0e-08	53	COG5499	Antitoxin component HigA of the HigAB toxin-antitoxin module, contains an N-terminal HTH domain	120
646765867	468	42.24	237	468	1	226	2.0e-66	246	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
646765868	244	23	8	213	2	214	3.0e-18	85.7	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
646765869	896	17.13	75	861	27	795	3.0e-63	237	COG3250	Beta-galactosidase/beta-glucuronidase	808
646765872	435	24.24	47	432	18	393	4.0e-19	89.5	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
646765874	177	36.54	1	154	3	155	2.0e-28	118	COG2153	Predicted N-acyltransferase, GNAT family	155
646765875	489	19.92	1	461	4	464	1.0e-11	65.1	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
646765877	453	39.51	28	311	4	268	8.0e-65	241	COG0836	Mannose-1-phosphate guanylyltransferase	333
646765878	187	35.19	20	174	4	159	1.0e-23	103	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
646765879	239	30.08	4	235	5	239	1.0e-32	133	COG2186	DNA-binding transcriptional regulator, FadR family	241
646765880	348	30.03	26	340	1	333	8.0e-33	134	COG0673	Predicted dehydrogenase	342
646765881	219	52.83	6	216	10	221	8.0e-59	219	COG0765	ABC-type amino acid transport system, permease component	222
646765882	264	42.22	6	264	3	272	6.0e-43	167	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
646765883	340	43.43	51	340	5	289	2.0e-84	305	COG0167	Dihydroorotate dehydrogenase	310
646765884	281	46.15	10	256	5	241	1.0e-78	286	COG2935	Arginyl-tRNA--protein-N-Asp/Glu arginylyltransferase	253
646765885	245	48.68	9	233	1	220	3.0e-69	254	COG2360	Leu/Phe-tRNA-protein transferase	221
646765886	181	37.24	29	167	1	145	1.0e-24	106	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
646765888	165	49.38	2	163	6	167	1.0e-47	182	COG4702	Uncharacterized protein, UPF0303 family	168
646765889	112	43.81	4	108	2	106	1.0e-19	88.2	COG2076	Multidrug transporter EmrE and related cation transporters	106
646765894	324	24.55	6	316	2	310	6.0e-20	91.9	COG0451	Nucleoside-diphosphate-sugar epimerase	314
646765895	278	23.16	4	193	3	191	9.0e-07	47.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
646765896	380	27.72	7	271	1	256	8.0e-33	134	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
646765898	386	36.01	6	357	1	331	2.0e-52	200	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
646765899	282	46.3	21	277	2	258	8.0e-59	220	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
646765900	341	50	72	303	3	242	2.0e-74	272	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
646765901	71	57.35	5	71	2	69	8.0e-12	61.9	COG3585	Molybdopterin-binding protein	69
646765907	333	34.65	9	330	10	319	2.0e-75	275	COG0042	tRNA-dihydrouridine synthase	323
646765910	75	52.17	1	69	1	69	9.0e-22	95	COG3530	Uncharacterized conserved protein, DUF3820 family	71
646765911	350	40.51	1	350	1	316	8.0e-86	310	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
646765912	474	24.24	5	456	1	408	6.0e-32	132	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
646765913	327	35.57	9	304	5	297	2.0e-30	126	COG0583	DNA-binding transcriptional regulator, LysR family	297
646765915	275	19.8	72	273	62	256	3.0e-08	52.5	COG1682	ABC-type polysaccharide/polyol phosphate export permease	263
646765916	304	44.63	6	300	5	293	7.0e-77	280	COG1131	ABC-type multidrug transport system, ATPase component	293
646765917	155	35.14	1	141	2	149	5.0e-11	60.8	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
646765920	216	39.17	1	215	1	201	4.0e-49	187	COG1974	SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase)	201
646765921	348	69.97	8	347	4	346	0.0e+00	524	COG1613	ABC-type sulfate transport system, periplasmic component	348
646765922	298	57.25	7	275	4	272	8.0e-74	270	COG0555	ABC-type sulfate transport system, permease component	274
646765923	334	72.44	9	291	4	286	1.0e-116	413	COG4208	ABC-type sulfate transport system, permease component	287
646765924	352	57.63	1	351	1	344	3.0e-111	395	COG1118	ABC-type sulfate/molybdate transport systems, ATPase component	345
646765925	308	28.67	1	298	1	294	4.0e-34	138	COG0583	DNA-binding transcriptional regulator, LysR family	297
646765928	372	46.87	40	369	14	346	3.0e-82	298	COG0252	L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D	351
646765929	303	48.6	2	284	1	286	2.0e-78	285	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
646765930	269	60.55	1	256	1	256	1.0e-104	372	COG3622	Hydroxypyruvate isomerase	260
646765931	591	81.36	1	590	1	590	0.0e+00	1072	COG3960	Glyoxylate carboligase	592
646765932	304	29.8	3	299	2	297	1.0e-35	143	COG0583	DNA-binding transcriptional regulator, LysR family	297
646765933	294	35.14	17	200	3	182	2.0e-29	122	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
646765934	315	20.2	9	305	10	256	3.0e-15	76.3	COG5662	Transmembrane transcriptional regulator (anti-sigma factor RsiW)	256
646765935	124	51.79	2	112	1	112	2.0e-35	140	COG0360	Ribosomal protein S6	112
646765936	99	31.31	2	99	5	103	5.0e-16	76.2	COG2965	Primosomal replication protein N	103
646765937	91	58.9	11	83	3	75	5.0e-21	92.6	COG0238	Ribosomal protein S18	75
646765938	150	58.39	1	149	1	148	5.0e-38	150	COG0359	Ribosomal protein L9	148
646765939	462	50.57	14	454	1	435	0.0e+00	554	COG0305	Replicative DNA helicase	435
646765940	208	29.91	1	207	4	217	8.0e-30	123	COG1392	Uncharacterized conserved protein YkaA, distantly related to PhoU, UPF0111/DUF47 family	217
646765941	336	41.64	8	331	2	321	1.0e-68	253	COG0306	Phosphate/sulfate permease	326
646765942	268	32.71	3	262	1	248	5.0e-32	131	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
646765943	361	36.31	9	173	19	197	5.0e-27	115	COG0791	Cell wall-associated hydrolase, NlpC family	197
646765944	615	50.11	153	615	1	436	0.0e+00	553	COG1875	Predicted ribonuclease YlaK, contains NYN-type RNase and PhoH-family ATPase domains	436
646765945	153	53.9	1	153	2	155	7.0e-56	209	COG1225	Peroxiredoxin	157
646765946	297	16.25	1	273	19	262	2.0e-12	66.6	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
646765947	348	24.71	2	337	1	311	6.0e-37	148	COG0451	Nucleoside-diphosphate-sugar epimerase	314
646765948	309	38.54	4	286	3	285	1.0e-74	273	COG0223	Methionyl-tRNA formyltransferase	307
646765949	347	24.23	11	300	3	289	7.0e-20	91.7	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
646765950	383	43.39	4	380	1	373	7.0e-115	407	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
646765952	584	28.34	7	559	2	535	2.0e-46	181	COG1807	4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferase of PMT family	535
646765953	124	41.94	1	122	5	127	3.0e-28	117	COG3737	Uncharacterized conserved protein, contains Mth938-like domain	127
646765954	415	34.96	11	410	1	393	2.0e-95	343	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
646765955	443	50.45	1	327	1	333	4.0e-99	355	COG0460	Homoserine dehydrogenase	333
646765956	483	30.17	1	479	1	410	2.0e-90	326	COG0498	Threonine synthase	411
646765957	411	43.48	1	409	6	404	7.0e-104	371	COG0303	Molybdopterin biosynthesis enzyme	404
646765958	85	35.71	2	85	1	84	1.0e-16	78.1	COG1977	Molybdopterin converting factor, small subunit	84
646765959	158	44.22	1	147	4	149	1.0e-41	161	COG0314	Molybdopterin synthase catalytic subunit	149
646765960	182	32.74	19	130	16	128	3.0e-17	81.5	COG2346	Truncated hemoglobin YjbI	133
646765961	176	39.13	1	137	1	134	3.0e-27	114	COG1959	DNA-binding transcriptional regulator, IscR family	150
646765962	865	55.31	5	864	1	785	0.0e+00	954	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
646765965	459	33.04	6	452	17	453	9.0e-58	218	COG0534	Na+-driven multidrug efflux pump	455
646765966	585	20.86	8	487	1	449	2.0e-19	90.9	COG1807	4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferase of PMT family	535
646765967	87	46.51	1	85	1	75	4.0e-20	89.5	COG0254	Ribosomal protein L31	75
646765968	277	43.87	1	269	1	253	7.0e-72	264	COG3228	Mlc titration factor MtfA, regulates ptsG expression	266
646765969	422	69.45	1	419	4	421	0.0e+00	696	COG1158	Transcription termination factor Rho	422
646765972	838	37.98	1	542	1	515	3.0e-130	459	COG2812	DNA polymerase III, gamma/tau subunits	515
646765973	108	58.49	1	105	2	105	1.0e-24	104	COG0718	Conserved DNA-binding protein YbaB (function unknown)	105
646765974	198	57.07	1	198	1	198	1.0e-75	275	COG0353	Recombinational DNA repair protein RecR	198
646765975	413	40.3	18	413	6	396	2.0e-112	399	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
646765976	345	28.36	11	345	7	334	1.0e-37	150	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
646765977	270	48.45	4	261	2	247	2.0e-86	312	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
646765978	274	35.63	8	268	7	257	8.0e-51	194	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
646765979	324	44.51	1	324	1	326	2.0e-76	279	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
646765980	252	55.56	1	246	1	252	1.0e-85	309	COG0496	Broad specificity polyphosphatase and 5'/3'-nucleotidase SurE	252
646765981	405	48.56	197	404	1	205	1.0e-60	227	COG2518	Protein-L-isoaspartate O-methyltransferase	209
646765982	316	31.34	71	315	1	263	1.0e-32	133	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
646765983	362	38.51	23	361	2	341	2.0e-69	256	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
646765985	476	34.54	36	469	7	432	6.0e-93	334	COG2265	tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family	432
646765986	286	36.61	32	285	12	253	7.0e-56	210	COG4105	Outer membrane protein assembly factor BamD, BamD/ComL family	254
646765987	416	48.47	72	365	6	288	7.0e-91	328	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
646765988	287	45.32	16	280	6	249	4.0e-64	238	COG1496	Copper oxidase (laccase) domain	249
646765989	601	50.65	138	599	1	445	0.0e+00	515	COG3243	Poly(3-hydroxyalkanoate) synthetase	445
646765990	393	50.74	1	393	1	392	3.0e-97	349	COG0183	Acetyl-CoA acetyltransferase	392
646765991	246	37.85	1	243	3	250	3.0e-47	181	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
646765992	205	38.8	4	178	3	185	2.0e-49	188	COG5394	Polyhydroxyalkanoate (PHA) synthesis regulator protein, binds DNA and PHA	193
646765993	347	34.5	1	311	10	314	9.0e-73	267	COG0042	tRNA-dihydrouridine synthase	323
646765994	480	36.58	31	480	2	435	8.0e-129	454	COG0621	tRNA A37 methylthiotransferase MiaB	437
646765995	311	35.13	10	311	1	309	2.0e-48	186	COG0524	Sugar or nucleoside kinase, ribokinase family	311
646765996	394	44.17	3	394	2	392	7.0e-86	311	COG0183	Acetyl-CoA acetyltransferase	392
646765998	394	34.84	3	394	1	396	1.0e-100	360	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
646765999	279	49.29	68	278	1	210	6.0e-52	197	COG0560	Phosphoserine phosphatase	212
646766000	411	36.69	1	411	6	411	8.0e-71	261	COG2124	Cytochrome P450	411
646766001	334	40.14	1	279	2	273	9.0e-70	257	COG1273	Non-homologous end joining protein Ku, dsDNA break repair	278
646766002	937	49.83	641	924	2	287	5.0e-86	313	COG3285	Eukaryotic-type DNA primase	299
646766004	322	30.56	18	312	1	297	4.0e-33	135	COG0583	DNA-binding transcriptional regulator, LysR family	297
646766005	338	36.47	1	336	1	325	1.0e-58	220	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
646766007	267	42.86	1	259	1	256	1.0e-60	226	COG0390	ABC-type iron transport system FetAB, permease component	256
646766008	246	36.94	8	229	3	219	2.0e-52	199	COG4619	ABC-type iron transport system FetAB, ATPase component	223
646766009	836	29.01	9	739	2	638	4.0e-89	323	COG2982	Uncharacterized protein involved in outer membrane biogenesis	648
646766014	657	36.33	233	520	57	336	2.0e-40	161	COG0642	Signal transduction histidine kinase	336
646766015	148	53.38	1	146	1	130	9.0e-39	152	COG1970	Large-conductance mechanosensitive channel	130
646766016	344	40.68	18	335	6	327	6.0e-76	277	COG1171	Threonine dehydratase	347
646766017	410	27.89	26	406	16	407	7.0e-61	228	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
646766018	1159	49.87	18	1148	7	1135	0.0e+00	1360	COG1197	Transcription-repair coupling factor (superfamily II helicase)	1139
646766019	237	48.73	1	234	1	229	5.0e-61	227	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	230
646766020	159	66.03	3	158	1	156	4.0e-60	223	COG0245	2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	159
646766021	182	39.15	1	182	2	181	3.0e-43	168	COG0450	Alkyl hydroperoxide reductase subunit AhpC (peroxiredoxin)	194
646766022	449	27.1	142	449	22	333	2.0e-31	130	COG0642	Signal transduction histidine kinase	336
646766023	244	48.93	11	242	2	229	2.0e-66	246	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
646766025	391	30.17	1	391	7	412	9.0e-67	247	COG4102	Uncharacterized conserved protein, DUF1501 family	418
646766026	278	36.59	4	277	10	282	2.0e-35	142	COG1562	Phytoene/squalene synthetase	288
646766029	149	28.8	20	144	2	126	2.0e-12	65.3	COG1846	DNA-binding transcriptional regulator, MarR family	126
646766030	381	44.27	10	376	3	372	9.0e-84	304	COG1929	Glycerate kinase	378
646766031	448	39.51	1	441	1	436	9.0e-95	341	COG0544	FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)	441
646766032	217	72.73	26	212	3	189	2.0e-85	308	COG0740	ATP-dependent protease ClpP, protease subunit	200
646766033	423	71.25	16	421	1	405	0.0e+00	688	COG1219	ATP-dependent protease Clp, ATPase subunit	408
646766034	806	69.24	10	782	6	782	0.0e+00	1190	COG0466	ATP-dependent Lon protease, bacterial type	782
646766035	90	60	1	90	2	91	3.0e-25	106	COG0776	Bacterial nucleoid DNA-binding protein	94
646766040	227	30.81	37	223	4	214	3.0e-21	95.8	COG2755	Lysophospholipase L1 or related esterase	216
646766041	228	62.27	8	227	6	224	2.0e-76	278	COG4181	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component	228
646766042	540	48.65	48	527	3	445	0.0e+00	495	COG0166	Glucose-6-phosphate isomerase	446
646766043	551	43	260	543	2	283	3.0e-54	206	COG0063	NAD(P)H-hydrate repair enzyme Nnr, NAD(P)H-hydrate dehydratase domain	284
646766044	431	24.66	1	431	5	385	2.0e-29	124	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
646766045	1360	33.63	172	1052	2	743	0.0e+00	695	COG0046	Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain	743
646766047	103	50.56	11	99	2	88	2.0e-20	90.8	COG0271	Stress-induced morphogen (activity unknown)	90
646766048	176	50.57	1	176	1	176	6.0e-47	180	COG2917	Intracellular septation protein A	180
646766049	140	58.59	14	140	2	129	3.0e-58	217	COG0229	Peptide methionine sulfoxide reductase MsrB	140
646766050	518	47.22	18	518	3	488	0.0e+00	583	COG0397	Uncharacterized conserved protein YdiU, UPF0061 family	488
646766051	565	36.48	9	537	6	527	7.0e-117	414	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
646766052	696	43.05	293	589	1	302	5.0e-85	309	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
646766053	392	40.44	1	390	1	390	7.0e-83	301	COG0183	Acetyl-CoA acetyltransferase	392
646766056	503	35.21	19	494	2	458	1.0e-96	346	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
646766057	161	37.8	13	137	13	139	6.0e-23	100	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
646766058	332	55.39	1	331	5	338	2.0e-121	429	COG2130	NADPH-dependent curcumin reductase CurA	340
646766059	293	31.92	6	265	6	242	3.0e-33	135	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
646766060	319	40.88	1	316	2	311	2.0e-53	202	COG0657	Acetyl esterase/lipase	312
646766061	288	41.54	1	249	1	241	2.0e-52	199	COG3332	Uncharacterized conserved protein, contains NRDE domain	270
646766062	355	29.03	45	354	16	304	3.0e-50	192	COG0354	Folate-binding Fe-S cluster repair protein YgfZ, possible role in tRNA modification	305
646766063	336	40.73	12	336	14	340	4.0e-96	344	COG1559	Cell division protein YceG, involved in septum cleavage	342
646766064	206	44.44	3	206	2	204	3.0e-56	211	COG0125	Thymidylate kinase	208
646766066	171	39.16	2	167	1	164	1.0e-40	159	COG1247	L-amino acid N-acyltransferase YncA	169
646766067	263	49.42	1	257	2	256	1.0e-79	289	COG0084	Tat protein secretion system quality control protein TatD (DNase activity)	256
646766070	407	23.58	65	290	9	233	1.0e-15	77.6	COG0668	Small-conductance mechanosensitive channel	316
646766071	470	45.55	1	461	14	483	0.0e+00	489	COG0380	Trehalose-6-phosphate synthase	486
646766072	355	23.88	6	342	2	381	1.0e-28	120	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
646766073	195	26.49	19	194	1	185	2.0e-29	122	COG2930	Lipid-binding SYLF domain	227
646766078	523	45.25	31	386	1	333	1.0e-110	394	COG0836	Mannose-1-phosphate guanylyltransferase	333
646766079	465	42.67	234	465	1	226	5.0e-68	252	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
646766080	481	50.8	1	437	1	414	0.0e+00	543	COG1004	UDP-glucose 6-dehydrogenase	414
646766081	151	25.17	1	151	1	139	5.0e-19	86.9	COG0394	Protein-tyrosine-phosphatase	139
646766082	401	34.1	57	317	11	239	3.0e-35	142	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
646766083	732	23.64	1	468	1	456	3.0e-40	160	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
646766084	313	21.97	1	306	3	304	1.0e-15	77.1	COG1216	Glycosyltransferase, GT2 family	305
646766085	386	20.48	50	360	54	381	2.0e-13	70.4	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
646766087	409	24.68	1	378	1	381	4.0e-33	135	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
646766088	388	29.31	7	384	1	380	6.0e-31	128	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
646766093	121	34.21	1	113	5	116	5.0e-16	76.8	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
646766094	347	58.6	5	344	3	345	0.0e+00	509	COG1089	GDP-D-mannose dehydratase	345
646766095	249	22.69	44	242	13	213	3.0e-06	46.1	COG2755	Lysophospholipase L1 or related esterase	216
646766096	360	28.17	1	356	1	379	2.0e-21	97.2	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
646766098	488	25.15	3	482	6	476	1.0e-13	71.7	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
646766099	817	23.45	435	817	4	380	5.0e-29	123	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
646766103	416	24.81	31	416	4	370	8.0e-22	98.3	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
646766105	305	61.64	1	291	1	291	1.0e-123	436	COG1210	UTP-glucose-1-phosphate uridylyltransferase	291
646766106	724	44.54	252	723	104	544	0.0e+00	487	COG2225	Malate synthase	545
646766107	134	44.2	1	134	2	139	7.0e-31	126	COG3193	Uncharacterized conserved protein GlcG, DUF336 family	141
646766108	297	33.22	1	291	1	261	6.0e-43	168	COG3217	Uncharacterized conserved protein YcbX, contains MOSC and Fe-S domains	270
646766109	266	43.39	6	245	4	244	3.0e-59	222	COG0007	Uroporphyrinogen-III methylase (siroheme synthase)	244
646766110	846	49.13	1	805	4	793	0.0e+00	1025	COG1251	NAD(P)H-nitrite reductase, large subunit	793
646766111	121	39.32	7	121	2	105	5.0e-17	80	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
646766112	1393	41.93	796	1393	3	587	0.0e+00	529	COG0369	Sulfite reductase, alpha subunit (flavoprotein)	587
646766113	455	32.37	7	448	7	413	6.0e-65	241	COG2223	Nitrate/nitrite transporter NarK	417
646766114	153	20	8	152	10	149	3.0e-11	61.2	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
646766115	121	28.26	23	114	16	107	1.0e-07	48.3	COG0640	DNA-binding transcriptional regulator, ArsR family	110
646766117	265	57.2	10	264	1	257	4.0e-85	307	COG4106	Trans-aconitate methyltransferase	257
646766118	299	33.78	3	295	1	292	3.0e-33	135	COG0583	DNA-binding transcriptional regulator, LysR family	297
646766119	207	33.5	2	200	1	200	4.0e-30	124	COG0625	Glutathione S-transferase	211
646766121	398	73.87	1	397	1	398	0.0e+00	655	COG3007	Trans-2-enoyl-CoA reductase	398
646766122	838	32.34	52	690	26	718	7.0e-127	448	COG5009	Membrane carboxypeptidase/penicillin-binding protein	797
646766123	450	22.32	6	426	21	436	6.0e-22	99.1	COG2271	Sugar phosphate permease	448
646766125	148	17.89	16	137	1	121	6.0e-08	50.2	COG1917	Cupin domain protein related to quercetin dioxygenase	131
646766126	227	35.12	1	204	2	202	2.0e-34	139	COG1182	FMN-dependent NADH-azoreductase	202
646766128	239	31.92	15	226	1	210	7.0e-42	163	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
646766129	228	28.64	5	219	4	212	5.0e-16	78.1	COG4094	Uncharacterized membrane protein	219
646766130	235	34.51	1	232	2	251	5.0e-34	138	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
646766131	154	26.76	10	151	5	128	2.0e-09	55.3	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
646766133	432	44.81	36	371	8	344	8.0e-80	291	COG1566	Multidrug resistance efflux pump	352
646766134	506	33.8	63	488	33	456	1.0e-52	201	COG1538	Outer membrane protein TolC	457
646766135	145	36.04	33	142	14	124	4.0e-12	64.2	COG1846	DNA-binding transcriptional regulator, MarR family	126
646766136	520	21.61	20	366	13	328	1.0e-15	78.3	COG2814	Predicted arabinose efflux permease, MFS family	394
646766138	236	33.59	1	233	1	251	8.0e-34	137	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
646766139	317	34	10	304	3	294	7.0e-36	144	COG0583	DNA-binding transcriptional regulator, LysR family	297
646766140	366	39.55	10	365	7	336	3.0e-56	212	COG2070	NAD(P)H-dependent flavin oxidoreductase YrpB, nitropropane dioxygenase family	336
646766141	402	24.8	25	402	19	390	4.0e-13	69.8	COG2814	Predicted arabinose efflux permease, MFS family	394
646766142	310	31.02	3	300	2	297	5.0e-28	118	COG0583	DNA-binding transcriptional regulator, LysR family	297
646766143	454	37.2	1	451	1	427	4.0e-84	305	COG1236	RNA processing exonuclease, beta-lactamase fold, Cft2 family	427
646766144	230	24.75	18	213	1	192	1.0e-19	90	COG2823	Osmotically-inducible protein OsmY, contains BON domain	196
646766145	144	34.03	1	144	4	144	1.0e-21	95.5	COG0071	Molecular chaperone IbpA, HSP20 family	146
646766148	413	37.29	12	187	3	179	7.0e-32	131	COG2059	Chromate transport protein ChrA	195
646766149	346	39.38	1	344	1	349	4.0e-73	268	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
646766151	340	27.27	9	321	5	301	1.0e-34	140	COG2334	Ser/Thr protein kinase RdoA involved in Cpx stress response, MazF antagonist	331
646766152	427	36.01	1	427	16	446	7.0e-112	397	COG0160	4-aminobutyrate aminotransferase or related aminotransferase	447
646766153	417	22.13	53	390	43	390	6.0e-12	65.6	COG2814	Predicted arabinose efflux permease, MFS family	394
646766154	492	47.41	12	492	1	469	0.0e+00	489	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
646766156	787	20.95	7	775	3	727	2.0e-76	280	COG1033	Predicted exporter protein, RND superfamily	727
646766167	185	27.27	6	173	2	177	5.0e-10	57.9	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
646766168	338	42.94	1	337	1	337	5.0e-95	341	COG1064	D-arabinose 1-dehydrogenase, Zn-dependent alcohol dehydrogenase family	339
646766169	752	73.15	1	752	12	730	0.0e+00	1188	COG0376	Catalase (peroxidase I)	730
646766170	414	24.61	67	383	26	283	1.0e-25	111	COG4974	Site-specific recombinase XerD	300
646766173	619	20.79	1	619	1	557	2.0e-44	174	COG0443	Molecular chaperone DnaK (HSP70)	579
646766177	296	31.38	6	292	1	290	6.0e-35	141	COG0583	DNA-binding transcriptional regulator, LysR family	297
646766179	164	25.71	17	154	5	123	1.0e-07	49.5	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
646766180	513	26.61	63	493	10	421	1.0e-49	191	COG4623	Membrane-bound lytic murein transglycosylase MltF	473
646766182	443	35.93	8	428	1	403	1.0e-126	446	COG0137	Argininosuccinate synthase	403
646766183	405	25.87	9	398	6	399	1.0e-34	141	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
646766184	309	32.25	5	309	3	292	1.0e-32	133	COG0583	DNA-binding transcriptional regulator, LysR family	297
646766185	267	23.11	3	214	1	197	2.0e-18	86.3	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
646766186	417	33.06	35	397	5	366	6.0e-87	314	COG0075	Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism protein PucG	383
646766187	299	31.8	1	278	1	279	3.0e-26	112	COG0583	DNA-binding transcriptional regulator, LysR family	297
646766188	248	42.57	3	246	2	249	8.0e-43	167	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
646766189	295	31.56	1	295	1	294	2.0e-27	116	COG0583	DNA-binding transcriptional regulator, LysR family	297
646766190	123	34.4	1	123	1	125	2.0e-16	77.7	COG2372	Copper-binding protein CopC (methionine-rich)	127
646766193	449	23.22	29	325	4	314	2.0e-18	87.6	COG2358	TRAP-type uncharacterized transport system, periplasmic component	321
646766194	299	25.79	114	271	7	164	3.0e-15	76.3	COG3109	sRNA-binding protein	208
646766195	453	30.47	105	439	1	326	3.0e-36	146	COG0642	Signal transduction histidine kinase	336
646766196	220	46.26	1	217	1	226	1.0e-55	209	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
646766197	277	29.63	10	275	2	257	6.0e-30	124	COG3394	Predicted glycoside hydrolase or deacetylase ChbG, UPF0249 family	257
646766200	219	42.79	1	219	1	228	7.0e-53	200	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
646766201	468	30	132	468	1	335	1.0e-36	148	COG0642	Signal transduction histidine kinase	336
646766204	386	23.4	20	368	26	377	2.0e-20	93.8	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
646766205	473	20.37	57	460	62	478	3.0e-31	130	COG1032	Radical SAM superfamily enzyme YgiQ, UPF0313 family	490
646766207	67	59.7	1	67	1	67	4.0e-24	102	COG1278	Cold shock protein, CspA family	67
646766208	481	42.8	9	478	1	467	1.0e-130	460	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
646766209	206	28.12	9	197	1	186	1.0e-17	83.1	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
646766211	278	62.23	1	278	1	278	8.0e-122	430	COG3717	5-keto 4-deoxyuronate isomerase	278
646766212	256	43.14	9	254	1	251	2.0e-41	162	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
646766213	299	43.09	43	287	1	246	1.0e-57	217	COG1414	DNA-binding transcriptional regulator, IclR family	246
646766217	460	19.28	17	452	21	446	2.0e-21	97.2	COG2271	Sugar phosphate permease	448
646766218	296	29.51	170	291	3	124	1.0e-17	83.8	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
646766219	396	24.11	1	386	1	387	5.0e-49	188	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
646766220	523	49.86	21	361	7	347	2.0e-113	403	COG1171	Threonine dehydratase	347
646766221	421	38.7	9	420	10	453	7.0e-87	314	COG3946	Type IV secretory pathway, VirJ component	456
646766222	901	44.36	377	898	8	530	6.0e-128	452	COG2898	Lysylphosphatidylglycerol synthetase, C-terminal domain, DUF2156 family	538
646766229	656	29.87	200	516	32	336	2.0e-36	147	COG0642	Signal transduction histidine kinase	336
646766231	352	31.15	18	332	5	305	3.0e-45	175	COG0492	Thioredoxin reductase	305
646766233	286	30.39	6	276	5	285	1.0e-26	113	COG0583	DNA-binding transcriptional regulator, LysR family	297
646766235	309	32.46	8	306	3	297	5.0e-39	155	COG0583	DNA-binding transcriptional regulator, LysR family	297
646766237	372	20.91	17	297	5	281	4.0e-14	72.5	COG1216	Glycosyltransferase, GT2 family	305
646766239	435	20	77	420	63	379	2.0e-08	54.1	COG2814	Predicted arabinose efflux permease, MFS family	394
646766240	507	60.24	13	505	8	494	0.0e+00	634	COG2719	Stage V sporulation protein SpoVR/YcgB, involved in spore cortex formation (function unknown)	495
646766241	423	51.31	2	419	1	418	0.0e+00	467	COG2718	Uncharacterized conserved protein YeaH/YhbH, required for sporulation, DUF444 family	423
646766242	640	67.95	1	640	1	649	0.0e+00	863	COG2766	Predicted Ser/Thr protein kinase	649
646766243	261	24.43	6	257	2	258	2.0e-17	83	COG3971	2-keto-4-pentenoate hydratase	264
646766244	588	35.29	130	512	1	408	6.0e-50	192	COG0840	Methyl-accepting chemotaxis protein	408
646766245	309	42.9	9	308	1	306	2.0e-45	176	COG0524	Sugar or nucleoside kinase, ribokinase family	311
646766246	347	49.7	2	335	1	330	1.0e-88	320	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
646766247	359	43.41	50	358	4	314	3.0e-57	216	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
646766248	530	50.59	7	511	3	500	0.0e+00	566	COG1129	ABC-type sugar transport system, ATPase component	500
646766249	324	33.13	1	324	2	313	4.0e-46	178	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
646766250	325	34.15	3	325	3	322	3.0e-64	239	COG0598	Mg2+ and Co2+ transporter CorA	322
646766254	372	28.03	8	359	2	371	1.0e-68	254	COG1748	Saccharopine dehydrogenase, NADP-dependent	389
646766255	152	34.23	4	149	1	149	3.0e-21	94.4	COG1522	DNA-binding transcriptional regulator, Lrp family	154
646766259	298	24.24	2	296	1	257	3.0e-28	119	COG4377	Uncharacterized membrane protein YhfC	258
646766260	357	36.84	20	357	1	331	9.0e-62	231	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
646766261	321	47.83	3	317	4	324	3.0e-89	321	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
646766262	429	21.62	8	418	24	443	9.0e-32	131	COG2271	Sugar phosphate permease	448
646766263	327	36.39	9	315	1	306	1.0e-46	180	COG0524	Sugar or nucleoside kinase, ribokinase family	311
646766265	296	33.78	1	293	1	289	4.0e-35	142	COG0583	DNA-binding transcriptional regulator, LysR family	297
646766266	359	40.41	13	351	2	330	3.0e-63	235	COG2855	Uncharacterized membrane protein YadS	334
646766268	577	34.61	5	447	3	443	7.0e-74	271	COG0038	H+/Cl- antiporter ClcA	443
646766272	355	33.55	4	300	3	297	3.0e-36	146	COG0583	DNA-binding transcriptional regulator, LysR family	297
646766274	205	26.49	7	191	5	186	1.0e-08	53.5	COG1309	DNA-binding transcriptional regulator, AcrR family	201
646766275	382	33.15	19	370	15	366	2.0e-20	94	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
646766276	1042	28.14	11	1021	1	1008	0.0e+00	765	COG0841	Multidrug efflux pump subunit AcrB	1009
646766277	524	32.87	69	502	24	457	8.0e-45	175	COG1538	Outer membrane protein TolC	457
646766278	846	48.64	58	777	4	736	0.0e+00	854	COG5009	Membrane carboxypeptidase/penicillin-binding protein	797
646766280	226	30.53	1	226	1	225	2.0e-17	83	COG1842	Phage shock protein A	225
646766283	496	29.67	4	457	1	443	2.0e-88	319	COG2072	Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD	443
646766285	272	42.26	5	268	10	267	2.0e-51	196	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
646766286	310	47.3	13	308	1	285	5.0e-72	264	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
646766287	389	48.88	31	387	5	350	7.0e-118	417	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
646766288	366	42.12	1	366	5	363	2.0e-86	313	COG0687	Spermidine/putrescine-binding periplasmic protein	363
646766289	433	42.32	11	432	1	414	2.0e-76	279	COG1914	Mn2+ and Fe2+ transporters of the NRAMP family	416
646766292	530	42.54	1	530	3	530	0.0e+00	574	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
646766293	313	40	1	304	1	285	5.0e-60	225	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
646766294	69	65.22	1	69	1	69	6.0e-22	95.8	COG3360	Flavin-binding protein dodecin	71
646766295	364	35.71	6	333	9	341	2.0e-71	263	COG1744	Basic membrane lipoprotein Med, periplasmic binding protein (PBP1-ABC) superfamily	345
646766296	309	46.23	1	305	2	300	4.0e-70	258	COG1079	ABC-type uncharacterized transport system, permease component	304
646766297	368	47.19	5	360	1	349	6.0e-82	298	COG4603	ABC-type uncharacterized transport system, permease component	356
646766298	532	49.31	18	514	3	501	0.0e+00	610	COG3845	ABC-type uncharacterized transport system, ATPase component	501
646766299	310	25.5	8	304	1	292	3.0e-29	122	COG0583	DNA-binding transcriptional regulator, LysR family	297
646766300	462	36.81	13	442	2	417	1.0e-76	280	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
646766301	117	63.25	1	117	8	124	9.0e-46	175	COG2351	5-hydroxyisourate hydrolase (purine catabolism), transthyretin-related family	124
646766302	397	48.28	1	395	1	404	2.0e-119	422	COG3748	Uncharacterized membrane protein	407
646766304	448	20.84	20	387	12	372	6.0e-16	78.9	COG3550	Serine/threonine protein kinase HipA, toxin component of the HipAB toxin-antitoxin module	392
646766305	170	55.95	1	167	1	168	2.0e-56	211	COG3194	Ureidoglycolate hydrolase (allantoin degradation)	168
646766306	336	59.28	1	333	1	333	0.0e+00	504	COG4266	Allantoicase	334
646766307	173	55.56	1	171	1	171	1.0e-55	209	COG3195	2-oxo-4-hydroxy-4-carboxy--5-ureidoimidazoline (OHCU) decarboxylase	176
646766308	316	27.04	5	305	1	267	7.0e-33	134	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
646766309	260	52.17	1	229	1	230	2.0e-64	239	COG4126	Asp/Glu/hydantoin racemase	230
646766310	493	38.1	16	493	7	485	2.0e-111	396	COG1953	Cytosine/uracil/thiamine/allantoin permease	497
646766311	237	34.51	1	224	6	230	1.0e-36	146	COG1802	DNA-binding transcriptional regulator, GntR family	230
646766312	308	43.28	6	301	12	309	1.0e-74	273	COG1619	Muramoyltetrapeptide carboxypeptidase LdcA (peptidoglycan recycling)	313
646766313	249	57.62	53	202	2	152	9.0e-46	177	COG0590	tRNA(Arg) A34 adenosine deaminase TadA	152
646766315	197	29.26	20	197	3	180	6.0e-19	87.7	COG1514	2'-5' RNA ligase	180
646766316	527	68.4	202	527	1	315	0.0e+00	542	COG0519	GMP synthase, PP-ATPase domain/subunit	315
646766318	486	29.86	255	475	1	170	8.0e-34	138	COG0516	IMP dehydrogenase/GMP reductase	170
646766319	328	21.97	1	305	5	289	4.0e-06	46	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
646766320	110	49.49	2	100	1	99	1.0e-23	101	COG2914	Putative antitoxin component PasI (RatB) of the RatAB toxin-antitoxin module, ubiquitin-RnfH superfamily	99
646766321	145	48.63	1	145	1	146	5.0e-48	183	COG2867	Ribosome association toxin PasT (RatA) of the RatAB toxin-antitoxin module	146
646766322	148	61.9	1	147	6	151	1.0e-54	205	COG0691	tmRNA-binding protein	153
646766323	315	41.51	4	261	3	267	2.0e-43	169	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
646766324	185	22.06	37	172	3	137	8.0e-09	53.8	COG1585	Membrane protein implicated in regulation of membrane protease activity	140
646766325	800	47.97	13	799	4	738	0.0e+00	733	COG0574	Phosphoenolpyruvate synthase/pyruvate phosphate dikinase	740
646766326	271	46.55	1	268	2	270	1.0e-81	296	COG1806	Regulator of PEP synthase PpsR, kinase-PPPase family (combines ADP:protein kinase and phosphorylase activities)	273
646766327	262	31.82	4	258	1	258	2.0e-42	166	COG0566	tRNA G18 (ribose-2'-O)-methylase SpoU	260
646766328	249	57.98	31	215	1	188	3.0e-64	238	COG0164	Ribonuclease HII	199
646766329	389	45.74	7	378	1	375	3.0e-112	398	COG0763	Lipid A disaccharide synthetase	381
646766330	262	57.25	1	262	3	260	1.0e-97	349	COG1043	Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase	260
646766331	154	55.94	8	148	4	144	4.0e-44	170	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
646766332	370	47.54	3	347	4	335	6.0e-94	338	COG1044	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase	338
646766333	175	36.31	10	173	3	170	1.0e-19	89.6	COG2825	Periplasmic chaperone for outer membrane proteins, Skp family	170
646766334	770	40.52	9	770	4	766	0.0e+00	667	COG4775	Outer membrane protein assembly factor BamA	766
646766336	401	56.81	3	390	2	384	0.0e+00	519	COG0743	1-deoxy-D-xylulose 5-phosphate reductoisomerase	385
646766337	273	36.4	1	272	1	261	8.0e-29	120	COG0575	CDP-diglyceride synthetase	265
646766338	260	55.6	14	244	14	245	3.0e-87	315	COG0020	Undecaprenyl pyrophosphate synthase	245
646766339	186	56.45	1	186	2	187	5.0e-64	237	COG0233	Ribosome recycling factor	187
646766340	237	61.18	1	236	1	237	3.0e-88	318	COG0528	Uridylate kinase	238
646766341	293	51.69	1	289	1	296	9.0e-84	303	COG0264	Translation elongation factor EF-Ts	296
646766342	250	59.83	3	236	4	236	3.0e-94	337	COG0052	Ribosomal protein S2	252
646766343	269	51.94	1	255	1	252	2.0e-93	336	COG0024	Methionine aminopeptidase	255
646766344	859	44.73	6	859	7	863	0.0e+00	834	COG2844	UTP:GlnB (protein PII) uridylyltransferase	867
646766345	177	43.75	1	160	2	156	5.0e-49	187	COG0242	Peptide deformylase	168
646766346	687	55.92	10	685	3	667	0.0e+00	921	COG0272	NAD-dependent DNA ligase	667
646766348	1172	33.39	1	1168	1	1163	0.0e+00	582	COG1196	Chromosome segregation ATPase	1163
646766349	349	20.4	3	296	1	292	7.0e-11	61.8	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
646766350	406	29.02	4	404	3	393	6.0e-73	268	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
646766351	275	52.69	2	274	1	270	6.0e-85	307	COG2171	Tetrahydrodipicolinate N-succinyltransferase	271
646766352	121	34.45	5	121	1	116	4.0e-26	109	COG1393	Arsenate reductase and related proteins, glutaredoxin family	117
646766353	379	36.96	5	379	16	408	8.0e-81	294	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
646766354	294	39.54	6	267	1	250	3.0e-52	199	COG2890	Methylase of polypeptide chain release factors	280
646766355	495	35.87	46	495	1	438	2.0e-81	296	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
646766356	159	65.41	1	159	2	160	3.0e-74	270	COG0386	Glutathione peroxidase, house-cleaning role in reducing lipid peroxides	162
646766357	651	46.36	1	526	3	529	0.0e+00	561	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
646766358	351	42.3	1	331	8	330	5.0e-78	284	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
646766360	458	60.74	1	455	1	454	0.0e+00	635	COG1066	Predicted ATP-dependent serine protease	456
646766361	356	47.91	1	352	1	355	3.0e-110	391	COG0787	Alanine racemase	360
646766363	268	53.58	4	268	2	263	2.0e-86	312	COG0351	Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase	263
646766364	333	29.73	21	272	5	251	4.0e-28	119	COG3782	Uncharacterized protein	289
646766365	332	43.58	142	310	9	186	5.0e-42	165	COG1573	Uracil-DNA glycosylase	202
646766366	164	29.01	13	156	16	177	7.0e-18	83.5	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
646766367	278	34.05	6	237	3	218	1.0e-35	143	COG1214	tRNA A37 threonylcarbamoyladenosine modification protein TsaB	220
646766368	89	61.63	3	88	1	86	1.0e-26	110	COG4281	Acyl-CoA-binding protein	87
646766369	544	39.45	35	542	28	505	3.0e-115	409	COG0513	Superfamily II DNA and RNA helicase	513
646766370	436	74.36	2	430	1	433	0.0e+00	668	COG2224	Isocitrate lyase	433
646766371	144	34.46	1	144	4	151	2.0e-17	81.6	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
646766372	300	27.72	3	299	2	297	6.0e-36	144	COG0583	DNA-binding transcriptional regulator, LysR family	297
646766373	272	24.9	8	243	3	227	2.0e-25	109	COG1011	FMN phosphatase YigB, HAD superfamily	229
646766374	530	47.05	4	530	8	541	0.0e+00	581	COG2225	Malate synthase	545
646766375	133	37.4	1	130	1	118	4.0e-16	77.2	COG2105	Uncharacterized conserved protein YtfP, gamma-glutamylcyclotransferase (GGCT)/AIG2-like family	120
646766376	299	33.07	147	272	1	127	7.0e-19	88	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
646766383	469	41.86	1	468	6	470	0.0e+00	469	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
646766384	314	35.15	45	308	1	293	5.0e-49	188	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
646766385	221	28.35	9	198	4	197	3.0e-30	125	COG0791	Cell wall-associated hydrolase, NlpC family	197
646766386	543	56.38	11	542	1	532	0.0e+00	675	COG4172	ABC-type microcin C transport system, duplicated ATPase component YejF	534
646766387	368	55.36	24	359	6	340	2.0e-124	439	COG4239	ABC-type microcin C transport system, permease component YejE	341
646766388	345	61.5	1	341	1	361	0.0e+00	500	COG4174	ABC-type microcin C transport system, permease component YejB	364
646766389	636	29.66	22	626	6	557	4.0e-82	299	COG4166	ABC-type oligopeptide transport system, periplasmic component	562
646766392	416	40.69	1	414	1	447	1.0e-112	400	COG0527	Aspartokinase	447
646766393	490	30.98	29	279	23	275	5.0e-45	175	COG0037	tRNA(Ile)-lysidine synthase TilS/MesJ	298
646766394	323	67.82	2	318	1	317	0.0e+00	502	COG0825	Acetyl-CoA carboxylase alpha subunit	317
646766396	465	55.53	3	465	1	464	0.0e+00	641	COG0215	Cysteinyl-tRNA synthetase	464
646766398	193	50.92	31	191	1	157	9.0e-51	193	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
646766399	164	49.09	1	163	1	157	4.0e-51	193	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
646766400	265	41.32	28	265	1	235	2.0e-51	195	COG2908	UDP-2,3-diacylglucosamine pyrophosphatase LpxH	237
646766401	277	54.92	1	193	3	194	2.0e-61	229	COG1045	Serine acetyltransferase	194
646766402	276	46.75	23	268	6	232	9.0e-65	240	COG0565	tRNA C32,U32 (ribose-2'-O)-methylase TrmJ or a related methyltransferase	242
646766403	266	47.69	1	257	1	260	2.0e-74	272	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
646766405	895	47.44	10	884	2	841	0.0e+00	934	COG0249	DNA mismatch repair ATPase MutS	843
646766407	180	43.1	1	169	1	168	7.0e-34	136	COG1047	FKBP-type peptidyl-prolyl cis-trans isomerase 2	174
646766408	417	38.96	35	415	6	383	1.0e-81	297	COG2850	Ribosomal protein L16 Arg81 hydroxylase, contains JmjC domain	383
646766409	750	34.32	47	744	1	648	6.0e-127	448	COG1199	Rad3-related DNA helicase	654
646766412	783	60.13	5	783	6	779	0.0e+00	1004	COG2183	Transcriptional accessory protein Tex/SPT6	780
646766413	628	57.85	5	628	8	627	0.0e+00	807	COG3158	K+ transporter	627
646766414	190	30.05	10	179	1	189	5.0e-28	117	COG2236	Hypoxanthine phosphoribosyltransferase	192
646766415	448	58.81	11	446	1	429	0.0e+00	644	COG0104	Adenylosuccinate synthase	430
646766416	383	38.72	2	382	1	388	3.0e-74	272	COG3705	ATP phosphoribosyltransferase regulatory subunit HisZ	390
646766417	63	35.71	6	61	4	59	3.0e-06	43.3	COG3242	Uncharacterized conserved protein YjeT, DUF2065 family	62
646766418	301	27.68	3	284	2	285	5.0e-33	134	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
646766419	467	21.65	86	373	2	282	6.0e-31	129	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
646766420	404	53.16	17	395	5	379	2.0e-117	416	COG2262	50S ribosomal subunit-associated GTPase HflX	411
646766421	78	69.33	3	76	2	76	4.0e-25	106	COG1923	sRNA-binding regulator protein Hfq	77
646766422	445	48.76	1	443	2	444	0.0e+00	565	COG1160	Predicted GTPases	444
646766423	381	24.06	14	376	12	367	1.0e-27	117	COG1520	Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat	370
646766424	209	33.65	2	209	3	207	1.0e-36	146	COG2976	Putative negative regulator of RcsB-dependent stress response	207
646766425	446	48.51	9	435	2	426	0.0e+00	482	COG0124	Histidyl-tRNA synthetase	429
646766426	438	45.12	28	437	1	361	3.0e-129	455	COG0821	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase IspG/GcpE	361
646766427	378	28.34	38	344	1	284	1.0e-22	100	COG1426	Cytoskeletal protein RodZ, contains Xre-like HTH and DUF4115 domains	284
646766428	383	52.76	7	366	2	348	5.0e-125	441	COG0820	Adenine C2-methylase RlmN of 23S rRNA A2503 and tRNA A37	349
646766429	141	63.16	2	134	1	133	3.0e-54	203	COG0105	Nucleoside diphosphate kinase	135
646766430	232	34.19	1	231	1	233	5.0e-27	114	COG0670	Integral membrane protein, interacts with FtsH	233
646766431	257	34.29	1	231	4	248	3.0e-32	132	COG1235	Phosphoribosyl 1,2-cyclic phosphodiesterase	269
646766432	379	30.65	15	379	9	342	1.0e-44	173	COG3317	Uncharacterized lipoprotein	342
646766433	305	52.38	14	304	4	297	4.0e-91	328	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
646766436	220	34.98	6	204	13	210	5.0e-17	81.2	COG1994	Zn-dependent protease (includes SpoIVFB)	230
646766437	211	43.48	2	207	1	206	4.0e-55	207	COG0009	tRNA A37 threonylcarbamoyladenosine synthetase subunit TsaC/SUA5/YrdC	211
646766438	276	44.92	1	255	2	253	2.0e-54	206	COG0613	Predicted metal-dependent phosphoesterase TrpH, contains PHP domain	258
646766439	294	24.23	5	294	1	280	1.0e-14	74	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
646766440	291	52.9	25	283	6	263	1.0e-81	296	COG2833	Uncharacterized conserved protein, contains ferritin-like DUF455 domain	268
646766441	174	47.7	1	174	2	175	1.0e-56	212	COG0663	Carbonic anhydrase or acetyltransferase, isoleucine patch superfamily	176
646766442	316	38.28	1	298	3	286	7.0e-80	290	COG1281	Redox-regulated molecular chaperone, HSP33 family	286
646766444	145	41.94	1	93	24	116	7.0e-19	86.5	COG2919	Cell division protein FtsB	117
646766445	427	68.78	1	426	1	423	0.0e+00	663	COG0148	Enolase	423
646766446	284	60.71	1	280	5	278	3.0e-122	431	COG2877	3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase	279
646766447	553	62.3	2	548	1	533	0.0e+00	876	COG0504	CTP synthase (UTP-ammonia lyase)	533
646766448	267	18.49	5	263	24	282	1.0e-11	63.6	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
646766449	877	32.76	564	853	19	280	4.0e-56	213	COG2333	Metal-dependent hydrolase, beta-lactamase superfamily II	293
646766450	262	38.67	1	254	2	254	5.0e-62	231	COG0084	Tat protein secretion system quality control protein TatD (DNase activity)	256
646766451	251	48.21	25	247	1	224	2.0e-77	282	COG1136	ABC-type lipoprotein export system, ATPase component	226
646766452	417	49.05	1	417	1	408	5.0e-112	398	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
646766453	366	30.45	27	356	3	309	1.0e-50	194	COG4255	Uncharacterized protein	318
646766454	568	42.35	39	538	4	477	3.0e-109	389	COG0608	Single-stranded DNA-specific exonuclease, DHH superfamily, may be involved in archaeal DNA replication intiation	491
646766455	367	66.11	130	367	1	239	4.0e-99	354	COG1186	Protein chain release factor B	239
646766456	518	58.48	20	518	5	502	0.0e+00	709	COG1190	Lysyl-tRNA synthetase (class II)	502
646766458	65	71.88	1	64	1	64	1.0e-19	88.5	COG2975	Fe-S-cluster formation regulator IscX/YfhJ	64
646766459	113	41.51	1	105	1	102	2.0e-16	77.4	COG0633	Ferredoxin	102
646766460	623	44.65	18	609	4	579	0.0e+00	516	COG0443	Molecular chaperone DnaK (HSP70)	579
646766461	175	36.69	8	174	3	171	4.0e-20	91.2	COG1076	DnaJ-domain-containing proteins 1	174
646766462	107	55.56	1	107	3	110	5.0e-37	145	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
646766463	137	52.7	1	129	5	149	9.0e-36	142	COG0822	NifU homolog involved in Fe-S cluster formation	150
646766464	407	61.7	8	391	1	386	0.0e+00	563	COG1104	Cysteine sulfinate desulfinase/cysteine desulfurase or related enzyme	386
646766465	176	39.72	1	141	1	138	1.0e-38	152	COG1959	DNA-binding transcriptional regulator, IscR family	150
646766466	166	38.99	2	160	1	139	2.0e-31	128	COG0394	Protein-tyrosine-phosphatase	139
646766469	471	44.3	2	463	1	459	0.0e+00	543	COG1139	L-lactate utilization protein LutB, contains a ferredoxin-type domain	459
646766471	308	41.7	44	285	1	246	1.0e-53	203	COG1414	DNA-binding transcriptional regulator, IclR family	246
646766472	404	33.45	131	399	19	291	2.0e-55	209	COG1686	D-alanyl-D-alanine carboxypeptidase	389
646766474	588	47.59	120	572	2	454	0.0e+00	474	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
646766475	560	47.84	125	560	1	403	3.0e-102	365	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
646766476	901	66.25	17	901	8	887	0.0e+00	1365	COG2609	Pyruvate dehydrogenase complex, dehydrogenase (E1) component	887
646766478	214	53.96	6	207	2	199	3.0e-65	241	COG4566	Two-component response regulator, FixJ family, consists of REC and HTH domains	202
646766479	287	61.21	4	283	1	281	1.0e-110	392	COG0190	5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase	283
646766480	701	54.22	1	697	1	683	0.0e+00	868	COG0339	Zn-dependent oligopeptidase	683
646766481	433	31.72	19	424	17	414	7.0e-61	228	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
646766482	231	57.14	1	231	1	230	1.0e-80	292	COG1794	Aspartate/glutamate racemase	230
646766484	283	48.85	27	282	2	259	1.0e-84	306	COG0708	Exonuclease III	261
646766485	705	40.52	17	703	3	648	0.0e+00	544	COG1505	Prolyl oligopeptidase PreP, S9A serine peptidase family	648
646766486	509	43.36	1	509	4	458	0.0e+00	491	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
646766487	380	43.3	30	378	11	354	3.0e-93	335	COG3852	Signal transduction histidine kinase, nitrogen specific	363
646766488	471	49.68	4	471	2	443	0.0e+00	529	COG0174	Glutamine synthetase	443
646766489	154	25.71	26	130	6	98	2.0e-06	45.7	COG0607	Rhodanese-related sulfurtransferase	110
646766490	282	28.15	1	266	2	252	3.0e-54	205	COG1058	Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA	255
646766492	332	25.09	28	295	1	250	6.0e-23	101	COG3000	Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily	271
646766495	1445	35.71	101	1064	7	845	0.0e+00	688	COG1643	HrpA-like RNA helicase	845
646766496	462	37.55	45	311	1	264	5.0e-67	248	COG0548	Acetylglutamate kinase	265
646766497	90	57.78	1	90	1	90	1.0e-34	138	COG2924	Fe-S cluster biosynthesis and repair protein YggX	90
646766498	489	19.69	66	451	46	393	4.0e-11	62.9	COG2814	Predicted arabinose efflux permease, MFS family	394
646766499	162	35	12	157	3	162	7.0e-26	110	COG0622	Predicted phosphodiesterase	172
646766501	191	35.64	1	186	10	197	2.0e-36	145	COG3548	Uncharacterized membrane protein	197
646766503	465	38.61	1	458	1	454	2.0e-115	409	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
646766508	477	35.4	1	477	3	457	2.0e-100	359	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
646766509	778	23.61	52	763	41	759	2.0e-94	340	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
646766510	167	32.76	1	162	51	220	1.0e-23	102	COG1451	Predicted metal-dependent hydrolase	223
646766512	355	38.42	3	339	1	333	5.0e-71	261	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
646766513	360	32.21	68	359	2	296	3.0e-47	182	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
646766514	274	31.62	7	274	8	274	4.0e-35	141	COG0555	ABC-type sulfate transport system, permease component	274
646766515	324	26.62	47	306	6	266	1.0e-36	147	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
646766516	348	45.09	8	347	6	350	4.0e-97	348	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
646766517	274	30.71	1	270	1	269	8.0e-27	114	COG1409	3',5'-cyclic AMP phosphodiesterase CpdA	301
646766518	399	25.26	6	388	1	380	2.0e-22	100	COG2814	Predicted arabinose efflux permease, MFS family	394
646766521	210	45.24	2	210	1	210	3.0e-49	188	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
646766522	180	34.29	38	176	6	138	1.0e-27	116	COG2193	Bacterioferritin (cytochrome b1)	157
646766525	545	30.86	251	518	98	364	2.0e-37	150	COG4585	Signal transduction histidine kinase	365
646766528	680	45.05	1	355	1	362	4.0e-104	372	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
646766531	267	33.06	36	266	2	243	2.0e-49	189	COG2041	Periplasmic DMSO/TMAO reductase YedYZ, molybdopterin-dependent catalytic subunit	271
646766532	216	42.21	23	216	20	216	4.0e-40	157	COG4117	Thiosulfate reductase cytochrome b subunit	221
646766533	287	26.47	18	287	6	259	2.0e-37	149	COG5429	Uncharacterized protein	261
646766536	643	63.81	136	611	1	432	0.0e+00	746	COG0422	Thiamine biosynthesis protein ThiC	432
646766539	532	38.48	12	529	1	522	1.0e-100	360	COG1620	L-lactate permease	522
646766541	409	22.57	7	408	4	341	4.0e-37	148	COG3317	Uncharacterized lipoprotein	342
646766546	568	31.89	29	461	1	409	3.0e-93	336	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
646766547	259	37.59	1	257	2	267	9.0e-37	147	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
646766549	475	21.45	102	365	11	260	1.0e-13	71.5	COG3396	1,2-phenylacetyl-CoA epoxidase, catalytic subunit	265
646766550	559	29.22	54	290	25	256	5.0e-19	89.8	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
646766551	332	34.39	150	305	1	155	2.0e-24	106	COG0703	Shikimate kinase	172
646766553	529	33.33	16	528	4	519	6.0e-99	354	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
646766554	286	24.64	47	284	19	281	1.0e-11	64.3	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
646766556	705	45.55	1	552	1	527	0.0e+00	532	COG3511	Phospholipase C	527
646766558	554	32.71	16	549	1	527	3.0e-122	432	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
646766560	302	29.7	1	298	1	296	3.0e-31	129	COG0583	DNA-binding transcriptional regulator, LysR family	297
646766561	706	44.64	303	578	6	285	2.0e-76	280	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
646766562	402	34.22	1	402	1	389	3.0e-65	242	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
646766563	383	29.2	1	375	1	382	3.0e-47	182	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
646766567	138	28.33	19	138	1	119	9.0e-13	65.9	COG0789	DNA-binding transcriptional regulator, MerR family	124
646766568	136	45.05	37	127	1	91	1.0e-28	118	COG0776	Bacterial nucleoid DNA-binding protein	94
646766569	811	40.54	149	810	1	650	0.0e+00	605	COG0072	Phenylalanyl-tRNA synthetase beta subunit	650
646766570	337	55.75	1	335	4	335	6.0e-117	414	COG0016	Phenylalanyl-tRNA synthetase alpha subunit	335
646766571	119	71.19	1	118	1	118	2.0e-39	154	COG0292	Ribosomal protein L20	118
646766572	65	58.46	1	65	1	65	3.0e-11	60.2	COG0291	Ribosomal protein L35	65
646766573	156	62.18	1	156	21	176	1.0e-56	212	COG0290	Translation initiation factor IF-3	176
646766574	635	56.48	34	634	1	583	0.0e+00	804	COG0441	Threonyl-tRNA synthetase	589
646766576	747	47.22	10	745	21	700	0.0e+00	740	COG0317	(p)ppGpp synthase/hydrolase, HD superfamily	701
646766577	117	34.75	5	116	12	129	3.0e-24	103	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
646766578	304	24.2	29	300	10	282	2.0e-15	77	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
646766579	213	64.59	3	210	6	214	3.0e-80	291	COG2057	Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit	225
646766580	234	58.64	1	220	1	219	2.0e-82	298	COG1788	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit	220
646766582	143	29.85	7	138	5	135	2.0e-22	98	COG0824	Acyl-CoA thioesterase FadM	137
646766583	258	40.15	5	255	1	250	4.0e-46	178	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
646766584	557	33.48	15	470	1	396	1.0e-73	271	COG0644	Dehydrogenase (flavoprotein)	396
646766585	366	58.15	2	362	1	367	0.0e+00	523	COG0082	Chorismate synthase	369
646766586	645	28.72	406	597	3	189	1.0e-25	111	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
646766587	155	30.51	6	120	1	116	2.0e-12	65.2	COG0517	CBS domain	117
646766588	445	59.52	6	425	8	426	0.0e+00	596	COG2873	O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent	426
646766589	277	28.41	17	272	15	282	1.0e-15	77.4	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
646766590	106	64.21	10	104	9	103	9.0e-33	131	COG4323	Uncharacterized protein	105
646766591	435	29.93	1	276	6	288	2.0e-40	160	COG1295	Uncharacterized membrane protein, BrkB/YihY/UPF0761 family (not an RNase)	303
646766592	200	34.45	1	198	3	207	9.0e-30	123	COG0655	Multimeric flavodoxin WrbA	207
646766593	172	46.03	33	155	6	130	2.0e-21	95.4	COG3308	Uncharacterized membrane protein	131
646766594	472	37.82	9	472	1	457	5.0e-89	321	COG0277	FAD/FMN-containing dehydrogenase	459
646766597	312	32.01	3	301	2	297	8.0e-40	157	COG0583	DNA-binding transcriptional regulator, LysR family	297
646766598	539	35.43	53	481	27	450	5.0e-62	232	COG1538	Outer membrane protein TolC	457
646766599	739	28.65	25	719	3	669	1.0e-75	278	COG1289	Uncharacterized membrane protein YccC	674
646766601	299	37.16	1	283	9	337	2.0e-64	239	COG1566	Multidrug resistance efflux pump	352
646766604	533	35.95	190	533	39	408	3.0e-42	167	COG0840	Methyl-accepting chemotaxis protein	408
646766605	421	23.18	56	411	31	384	8.0e-16	78.7	COG2814	Predicted arabinose efflux permease, MFS family	394
646766608	634	38.48	45	608	1	524	0.0e+00	533	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
646766609	264	35.25	15	257	5	230	1.0e-37	150	COG0775	Nucleoside phosphorylase	234
646766610	795	43.61	16	696	1	654	0.0e+00	577	COG0210	Superfamily I DNA or RNA helicase	655
646766611	959	50.37	12	957	1	875	0.0e+00	1180	COG0525	Valyl-tRNA synthetase	877
646766612	293	64.24	1	287	1	287	6.0e-125	440	COG1210	UTP-glucose-1-phosphate uridylyltransferase	291
646766613	77	40	3	76	2	76	3.0e-18	83.4	COG0425	TusA-related sulfurtransferase	78
646766614	348	31.61	7	348	3	340	5.0e-50	191	COG0673	Predicted dehydrogenase	342
646766615	338	32.75	7	336	3	342	4.0e-49	188	COG0673	Predicted dehydrogenase	342
646766616	294	30.4	12	280	1	262	2.0e-49	189	COG1737	DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains	281
646766617	348	20.98	7	347	6	322	3.0e-30	126	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
646766618	396	34.76	46	395	2	316	2.0e-52	199	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
646766620	673	49.03	354	659	3	307	1.0e-98	354	COG3892	Myo-inositol catabolism protein IolC	310
646766621	657	60.52	26	641	4	614	0.0e+00	824	COG3962	TPP-dependent trihydroxycyclohexane-1,2-dione (THcHDO) dehydratase, myo-inositol metabolism	617
646766622	302	30.2	8	295	1	274	6.0e-35	141	COG1082	Sugar phosphate isomerase/epimerase	274
646766623	266	56.39	2	265	3	268	2.0e-96	345	COG3718	5-deoxy-D-glucuronate isomerase	270
646766624	241	47.08	3	240	2	237	3.0e-69	255	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
646766625	266	43.2	1	246	1	250	2.0e-66	246	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
646766626	428	32.36	17	319	9	314	9.0e-32	131	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
646766627	312	36.62	1	308	3	293	2.0e-38	153	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
646766628	149	33.81	9	145	1	137	4.0e-24	104	COG0824	Acyl-CoA thioesterase FadM	137
646766629	382	41.79	1	382	1	377	2.0e-104	373	COG1454	Alcohol dehydrogenase, class IV	377
646766631	343	43.06	1	342	1	342	1.0e-112	399	COG2008	Threonine aldolase	342
646766633	306	37.41	1	287	1	289	6.0e-35	141	COG0583	DNA-binding transcriptional regulator, LysR family	297
646766634	874	55.96	1	874	6	879	0.0e+00	1162	COG0013	Alanyl-tRNA synthetase	879
646766635	406	49.14	1	406	5	396	3.0e-128	451	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
646766636	186	44.94	6	182	3	175	3.0e-42	164	COG3545	Predicted esterase of the alpha/beta hydrolase fold	181
646766637	601	41.74	46	600	1	539	0.0e+00	502	COG0405	Gamma-glutamyltranspeptidase	539
646766638	574	32.01	30	549	3	472	1.0e-97	351	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
646766639	329	24.13	31	309	1	275	1.0e-32	133	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
646766640	149	30.47	7	123	5	131	2.0e-08	51.6	COG4119	Predicted NTP pyrophosphohydrolase, NUDIX family	161
646766642	521	39.57	167	514	35	408	7.0e-49	188	COG0840	Methyl-accepting chemotaxis protein	408
646766644	276	33.94	1	272	4	270	6.0e-44	171	COG1968	Undecaprenyl pyrophosphate phosphatase UppP	270
646766645	302	24.27	1	299	6	306	3.0e-31	129	COG2017	Galactose mutarotase or related enzyme	308
646766646	237	30.42	29	236	1	263	9.0e-28	117	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
646766648	102	47.37	9	102	2	96	1.0e-19	88.2	COG5626	Uncharacterized protein	97
646766649	475	28.77	44	470	16	445	5.0e-57	215	COG0534	Na+-driven multidrug efflux pump	455
646766654	152	39.13	1	131	2	139	9.0e-26	109	COG2062	Phosphohistidine phosphatase SixA	163
646766655	270	40.28	1	267	1	287	6.0e-55	207	COG3176	Putative hemolysin	292
646766656	557	39.27	61	546	4	492	9.0e-113	400	COG0248	Exopolyphosphatase/pppGpp-phosphohydrolase	492
646766657	687	53.82	8	682	12	683	0.0e+00	884	COG0855	Polyphosphate kinase	696
646766658	437	30.62	73	425	86	447	3.0e-48	186	COG5002	Signal transduction histidine kinase	459
646766659	233	47.64	5	233	3	229	8.0e-62	230	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
646766660	234	38.96	4	234	7	236	1.0e-36	146	COG0704	Phosphate uptake regulator	240
646766661	282	65.35	29	282	1	253	2.0e-127	448	COG1117	ABC-type phosphate transport system, ATPase component	253
646766662	298	48.78	18	298	2	288	6.0e-68	251	COG0581	ABC-type phosphate transport system, permease component	292
646766663	333	48.11	16	328	4	308	2.0e-72	266	COG0573	ABC-type phosphate transport system, permease component	310
646766664	343	37.27	8	322	28	318	4.0e-61	228	COG0226	ABC-type phosphate transport system, periplasmic component	318
646766665	452	45.79	1	448	5	458	2.0e-112	399	COG1109	Phosphomannomutase	464
646766666	321	46.38	47	318	6	272	2.0e-71	262	COG0294	Dihydropteroate synthase	274
646766667	629	58.86	10	600	1	596	0.0e+00	750	COG0465	ATP-dependent Zn proteases	596
646766668	220	45.58	5	219	2	204	4.0e-65	241	COG0293	23S rRNA U2552 (ribose-2'-O)-methylase RlmE/FtsJ	205
646766669	175	36.08	5	101	1	97	3.0e-19	88.3	COG1534	RNA-binding protein YhbY	97
646766671	160	51.63	8	160	1	151	3.0e-39	154	COG0782	Transcription elongation factor, GreA/GreB family	151
646766672	1088	69.98	13	415	1	393	0.0e+00	575	COG0458	Carbamoylphosphate synthase large subunit	400
646766673	384	58.78	5	379	1	368	0.0e+00	567	COG0505	Carbamoylphosphate synthase small subunit	368
646766674	413	20.47	9	393	15	386	1.0e-12	67.5	COG2814	Predicted arabinose efflux permease, MFS family	394
646766676	263	27.84	7	231	17	252	1.0e-17	83.8	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
646766678	148	61.54	3	142	1	143	5.0e-52	196	COG0328	Ribonuclease HI	154
646766679	244	36.97	1	234	13	243	1.0e-44	173	COG0847	DNA polymerase III, epsilon subunit or related 3'-5' exonuclease	243
646766682	624	35.69	29	594	14	567	2.0e-117	416	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
646766683	154	25.83	1	149	1	150	3.0e-13	67.6	COG3556	Uncharacterized membrane protein	150
646766685	354	24.41	6	343	2	381	4.0e-28	118	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
646766686	641	34.32	51	624	1	567	9.0e-114	404	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
646766687	492	45.32	1	459	14	479	0.0e+00	483	COG0380	Trehalose-6-phosphate synthase	486
646766688	249	38.4	2	248	8	257	7.0e-54	204	COG1877	Trehalose-6-phosphatase	266
646766689	208	38.05	5	207	5	207	9.0e-40	156	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
646766690	153	36.17	10	149	5	143	1.0e-22	99.2	COG2847	Copper(I)-binding protein	151
646766691	294	28.46	17	280	24	273	3.0e-21	95.8	COG3336	Cytochrome c oxidase assembly factor CtaG	299
646766692	166	46.71	15	164	3	149	3.0e-41	160	COG2153	Predicted N-acyltransferase, GNAT family	155
646766693	326	41.81	145	321	1	177	3.0e-33	136	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
646766694	249	28.29	7	243	41	290	7.0e-20	91.1	COG3735	Uncharacterized conserved protein YbaP, TraB family	299
646766698	197	40.51	1	194	10	192	1.0e-22	99.7	COG0558	Phosphatidylglycerophosphate synthase	192
646766700	397	44.71	21	397	5	370	3.0e-103	368	COG4394	Uncharacterized protein	370
646766701	185	42.64	1	128	3	131	6.0e-33	134	COG0231	Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)	131
646766702	66	36.21	2	59	6	63	1.0e-07	48	COG3237	Uncharacterized conserved protein YjbJ, UPF0337 family	67
646766703	481	39.32	22	481	4	457	6.0e-103	368	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
646766704	342	42.77	1	313	1	309	8.0e-74	271	COG1472	Periplasmic beta-glucosidase and related glycosidases	397
646766705	155	41.09	2	129	1	124	2.0e-30	124	COG0736	Phosphopantetheinyl transferase (holo-ACP synthase)	127
646766706	254	64.2	11	250	1	243	4.0e-91	327	COG0854	Pyridoxine 5'-phosphate synthase PdxJ	243
646766707	301	34.16	64	298	1	243	7.0e-44	171	COG1381	Recombinational DNA repair protein (RecF pathway)	251
646766708	287	50.34	1	287	8	296	6.0e-99	354	COG1159	GTPase Era, involved in 16S rRNA processing	298
646766709	426	49.77	2	217	7	226	7.0e-65	241	COG0571	dsRNA-specific ribonuclease	235
646766710	297	29.03	74	226	8	146	6.0e-15	75	COG0681	Signal peptidase I	166
646766711	597	69.06	1	597	6	603	0.0e+00	1053	COG0481	Translation elongation factor EF-4, membrane-bound GTPase	603
646766713	504	41.43	10	394	7	345	5.0e-72	265	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
646766714	346	30.42	14	344	5	318	1.0e-62	234	COG3026	Negative regulator of sigma E activity	320
646766715	204	18.78	15	202	8	213	6.0e-08	50.8	COG3073	Negative regulator of sigma E activity	213
646766716	199	39.04	7	193	2	181	2.0e-34	138	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
646766718	412	57.28	2	411	1	410	0.0e+00	512	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
646766719	79	65.38	1	78	3	80	1.0e-12	64.6	COG0236	Acyl carrier protein	80
646766720	249	50.2	5	246	3	250	4.0e-49	188	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
646766721	311	51.62	1	306	2	309	5.0e-94	338	COG0331	Malonyl CoA-acyl carrier protein transacylase	310
646766722	329	54.88	5	329	1	322	2.0e-114	405	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
646766723	368	52.55	3	333	2	334	2.0e-119	422	COG0416	Fatty acid/phospholipid biosynthesis enzyme	338
646766724	59	45.61	1	56	1	57	4.0e-12	63	COG0333	Ribosomal protein L32	57
646766726	205	41.54	8	202	2	192	1.0e-46	179	COG0424	Predicted house-cleaning NTP pyrophosphatase, Maf/HAM1 superfamily	193
646766727	239	33.47	1	239	3	226	2.0e-44	173	COG0313	16S rRNA C1402 (ribose-2'-O) methylase RsmI	275
646766728	333	28.75	25	332	1	317	3.0e-57	215	COG0616	Periplasmic serine protease, ClpP class	317
646766729	138	26.47	17	118	6	98	1.0e-11	62.7	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
646766730	219	34.4	4	217	2	219	4.0e-40	158	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
646766731	349	38.33	28	324	4	288	2.0e-71	262	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
646766733	1066	51.42	1	492	1	487	0.0e+00	513	COG1530	Ribonuclease G or E	487
646766734	369	47.66	28	369	2	322	6.0e-103	367	COG2896	Molybdenum cofactor biosynthesis enzyme MoaA	322
646766735	208	41.41	8	203	5	190	1.0e-38	152	COG0746	Molybdopterin-guanine dinucleotide biosynthesis protein A	192
646766736	477	42.38	58	476	7	404	1.0e-104	373	COG0303	Molybdopterin biosynthesis enzyme	404
646766738	482	33.73	53	470	23	419	2.0e-71	263	COG1322	DNA anti-recombination protein (rearrangement mutator) RmuC	448
646766739	329	46.15	3	321	4	323	4.0e-91	328	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
646766740	511	22.12	68	509	2	423	3.0e-50	193	COG1055	Na+/H+ antiporter NhaD or related arsenite permease	424
646766741	220	31.36	6	220	3	218	8.0e-37	147	COG1556	L-lactate utilization protein LutC, contains LUD domain	218
646766742	398	35.06	1	398	9	385	2.0e-87	316	COG1488	Nicotinic acid phosphoribosyltransferase	405
646766743	107	37.88	4	65	5	68	5.0e-08	49.4	COG1146	NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit	68
646766746	158	54.38	1	158	3	161	6.0e-49	186	COG3045	Periplasmic catabolite regulation protein CreA (function unknown)	165
646766747	280	32.52	157	278	1	123	6.0e-19	88	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
646766748	253	35.14	15	235	9	228	3.0e-37	148	COG1296	Predicted branched-chain amino acid permease (azaleucine resistance)	238
646766749	107	41	1	100	4	102	9.0e-11	58.6	COG4392	Branched-chain amino acid transport protein	107
646766751	731	32.94	38	699	2	649	1.0e-118	420	COG0210	Superfamily I DNA or RNA helicase	655
646766755	72	43.08	8	72	7	71	2.0e-16	77.2	COG2501	Ribosome-associated protein YbcJ, S4-like RNA binding protein	73
646766756	471	34.31	25	464	21	454	7.0e-58	218	COG0534	Na+-driven multidrug efflux pump	455
646766757	319	43.71	5	305	11	312	2.0e-63	235	COG0385	Predicted Na+-dependent transporter	319
646766758	525	29.2	39	487	46	434	1.0e-53	204	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
646766759	465	69.41	3	463	1	461	0.0e+00	776	COG0114	Fumarate hydratase class II	462
646766760	168	42.18	5	151	5	151	1.0e-38	152	COG1607	Acyl-CoA hydrolase	157
646766762	237	32.98	1	94	1	94	6.0e-10	57.9	COG0640	DNA-binding transcriptional regulator, ArsR family	110
646766764	323	39.81	1	323	3	268	2.0e-67	249	COG0207	Thymidylate synthase	268
646766765	464	43.64	19	442	20	456	2.0e-110	393	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
646766771	237	31.55	26	193	5	164	6.0e-24	104	COG3271	Predicted double-glycine peptidase	201
646766774	519	41.23	62	499	4	456	7.0e-106	378	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
646766775	166	44.38	3	164	1	167	4.0e-38	150	COG0262	Dihydrofolate reductase	167
646766776	456	38.55	21	455	3	453	3.0e-87	316	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
646766777	205	42.16	4	187	6	187	3.0e-38	151	COG3028	Ribosomal 50S subunit-associated protein YjgA (function unknown), DUF615 family	187
646766778	214	45.86	16	195	5	168	1.0e-43	170	COG0521	Molybdopterin biosynthesis enzyme MoaB	169
646766779	203	65.19	13	193	1	181	1.0e-77	282	COG1949	Oligoribonuclease (3'-5' exoribonuclease)	184
646766780	419	24.83	125	417	11	295	4.0e-19	89.6	COG0501	Zn-dependent protease with chaperone function	302
646766781	329	40.76	23	329	6	297	5.0e-76	277	COG1162	Putative ribosome biogenesis GTPase RsgA	301
646766783	312	30.43	1	312	8	319	2.0e-40	159	COG1270	Cobalamin biosynthesis protein CobD/CbiB	320
646766785	128	62.71	1	118	3	115	7.0e-37	146	COG0335	Ribosomal protein L19	115
646766786	255	46.53	1	244	1	239	2.0e-91	329	COG0336	tRNA G37 N-methylase TrmD	240
646766787	244	37.43	67	244	4	172	5.0e-37	148	COG0806	Ribosomal 30S subunit maturation factor RimM, required for 16S rRNA processing	174
646766788	84	61.9	1	84	1	84	6.0e-27	112	COG0228	Ribosomal protein S16	87
646766789	394	29.75	42	392	59	397	8.0e-57	214	COG2133	Glucose/arabinose dehydrogenase, beta-propeller fold	399
646766791	383	42.32	53	345	2	289	2.0e-76	279	COG1533	DNA repair photolyase	297
646766792	162	40.67	6	155	1	149	3.0e-34	138	COG1522	DNA-binding transcriptional regulator, Lrp family	154
646766793	428	29.6	1	418	5	384	3.0e-48	186	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
646766794	596	33.49	35	460	7	393	3.0e-66	247	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
646766795	315	54.23	1	315	1	311	6.0e-83	300	COG2025	Electron transfer flavoprotein, alpha subunit	313
646766796	249	51.92	1	249	1	260	1.0e-68	252	COG2086	Electron transfer flavoprotein, alpha and beta subunits	260
646766797	265	57.3	1	265	2	268	2.0e-92	332	COG1464	ABC-type metal ion transport system, periplasmic component/surface antigen	268
646766798	217	63.59	1	217	6	222	3.0e-75	274	COG2011	ABC-type methionine transport system, permease component	222
646766799	356	61.81	13	354	1	339	7.0e-128	450	COG1135	ABC-type methionine transport system, ATPase component	339
646766800	301	35.44	27	297	15	295	9.0e-46	177	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
646766801	269	37.9	23	267	12	257	1.0e-42	166	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
646766802	307	45.51	1	305	2	310	2.0e-84	306	COG0123	Acetoin utilization deacetylase AcuC or a related deacetylase	340
646766803	422	32.01	15	392	4	339	3.0e-61	229	COG2951	Membrane-bound lytic murein transglycosylase B	343
646766804	300	47.19	3	295	2	300	2.0e-96	345	COG0031	Cysteine synthase	300
646766806	330	26.95	1	326	1	308	6.0e-39	155	COG0451	Nucleoside-diphosphate-sugar epimerase	314
646766808	467	54.65	1	441	1	414	0.0e+00	564	COG1004	UDP-glucose 6-dehydrogenase	414
646766809	391	43.41	2	385	1	386	4.0e-117	415	COG2956	Lipopolysaccharide biosynthesis regulator YciM, contains six TPR domains and a predicted metal-binding C-terminal domain	389
646766810	97	34.62	1	78	22	98	5.0e-08	49.5	COG5416	Uncharacterized integral membrane protein	98
646766811	107	51.09	1	92	2	92	2.0e-25	107	COG0776	Bacterial nucleoid DNA-binding protein	94
646766812	577	58.16	16	547	1	524	0.0e+00	601	COG0539	Ribosomal protein S1	541
646766813	227	56.48	9	222	3	218	3.0e-66	245	COG0283	Cytidylate kinase	222
646766814	434	47.49	1	431	1	424	1.0e-129	456	COG0128	5-enolpyruvylshikimate-3-phosphate synthase	428
646766815	313	40.07	8	298	2	279	1.0e-62	234	COG0287	Prephenate dehydrogenase	279
646766816	373	46.58	10	371	6	356	1.0e-92	333	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
646766817	359	52.01	93	359	4	276	4.0e-92	331	COG0077	Prephenate dehydratase	279
646766818	360	57.62	1	358	4	363	0.0e+00	482	COG1932	Phosphoserine aminotransferase	365
646766820	860	56.55	1	837	17	804	0.0e+00	1043	COG0188	DNA gyrase/topoisomerase IV, subunit A	804
646766821	215	26.9	17	212	1	190	2.0e-26	112	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
646766822	232	54.66	1	232	9	243	2.0e-84	305	COG2227	2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase	243
646766823	237	38.14	22	233	6	217	9.0e-41	160	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
646766824	122	42.74	6	122	23	138	1.0e-23	101	COG4315	Predicted lipoprotein with conserved Yx(FWY)xxD motif (function unknown)	138
646766826	359	37.21	134	348	8	220	3.0e-42	166	COG1910	Periplasmic molybdate-binding protein/domain	223
646766827	161	31.47	10	152	14	155	4.0e-31	127	COG1905	NADH:ubiquinone oxidoreductase 24 kD subunit (chain E)	160
646766828	524	51.92	93	507	1	416	0.0e+00	529	COG1894	NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F)	424
646766829	1012	45.03	71	1003	2	972	0.0e+00	1197	COG3383	Predicted molibdopterin-dependent oxidoreductase YjgC	978
646766831	564	28.24	10	396	4	386	8.0e-45	175	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
646766832	628	27.16	78	317	31	238	6.0e-14	73.1	COG3063	Tfp pilus assembly protein PilF	250
646766833	433	19.58	51	425	44	390	1.0e-09	58.3	COG2814	Predicted arabinose efflux permease, MFS family	394
646766834	174	21.39	6	174	11	175	2.0e-10	59.2	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
646766836	467	33.99	215	465	6	241	4.0e-45	176	COG2071	Gamma-glutamyl-gamma-aminobutyrate hydrolase PuuD (putrescine degradation), contains GATase1-like domain	243
646766837	585	33.91	1	399	1	405	2.0e-54	207	COG4651	Predicted Kef-type K+ transport protein, K+/H+ antiporter domain	408
646766838	459	36.84	3	455	1	467	5.0e-87	315	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
646766839	169	30.12	1	163	2	165	1.0e-15	76.2	COG1495	Disulfide bond formation protein DsbB	170
646766840	539	52.66	28	531	4	493	0.0e+00	603	COG4630	Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A	493
646766841	829	59.72	9	789	5	781	0.0e+00	1081	COG4631	Xanthine dehydrogenase, molybdopterin-binding subunit B	781
646766842	338	26.36	4	332	3	264	6.0e-35	141	COG1975	Xanthine and CO dehydrogenase maturation factor, XdhC/CoxF family	278
646766843	349	45.27	18	348	8	342	2.0e-91	329	COG1816	Adenosine deaminase	345
646766844	454	33.49	19	439	3	420	6.0e-77	281	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
646766845	414	22.52	9	413	2	392	1.0e-34	141	COG0644	Dehydrogenase (flavoprotein)	396
646766846	426	44.69	4	409	1	411	6.0e-98	351	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
646766847	407	41.3	1	406	2	411	8.0e-110	390	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
646766848	241	40.48	1	241	4	251	4.0e-38	151	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
646766849	164	40.14	18	161	12	158	3.0e-30	124	COG4706	Predicted 3-hydroxylacyl-ACP dehydratase, HotDog domain	161
646766850	393	31.23	4	393	3	410	3.0e-64	239	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
646766851	819	38.43	7	809	4	786	0.0e+00	597	COG4258	Predicted exporter	788
646766852	236	17.45	19	229	5	196	5.0e-07	48.4	COG2834	Outer membrane lipoprotein-sorting protein	211
646766853	146	35.48	14	136	7	128	2.0e-23	101	COG0824	Acyl-CoA thioesterase FadM	137
646766854	540	41.54	27	530	2	498	9.0e-129	454	COG2986	Histidine ammonia-lyase	498
646766855	578	49.18	268	571	4	303	4.0e-100	359	COG4261	Predicted acyltransferase, LPLAT superfamily	309
646766857	222	43.5	20	218	1	198	6.0e-40	157	COG4648	Uncharacterized membrane protein	201
646766858	83	36.25	1	80	1	80	2.0e-11	60.7	COG0236	Acyl carrier protein	80
646766860	264	31.19	21	231	1	218	5.0e-23	101	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
646766862	217	46.24	30	215	2	185	8.0e-45	173	COG2119	Putative Ca2+/H+ antiporter, TMEM165/GDT1 family	190
646766864	898	39.58	1	892	3	859	0.0e+00	623	COG0308	Aminopeptidase N	859
646766865	338	54.52	6	337	1	326	5.0e-129	454	COG0158	Fructose-1,6-bisphosphatase	326
646766869	198	33.77	38	113	24	100	5.0e-12	64.6	COG1605	Chorismate mutase	101
646766871	67	55.22	1	67	1	67	1.0e-22	97.9	COG1278	Cold shock protein, CspA family	67
646766873	387	24.43	1	387	1	354	1.0e-44	174	COG3203	Outer membrane protein (porin)	354
646766874	189	43.79	32	183	1	151	2.0e-35	141	COG0782	Transcription elongation factor, GreA/GreB family	151
646766878	786	42.82	61	762	16	700	0.0e+00	826	COG0317	(p)ppGpp synthase/hydrolase, HD superfamily	701
646766879	67	49.28	1	66	1	69	1.0e-12	64.6	COG1758	DNA-directed RNA polymerase, subunit K/omega	74
646766880	227	55.68	22	206	4	187	2.0e-70	258	COG0194	Guanylate kinase	191
646766881	307	43.69	1	307	1	290	9.0e-71	260	COG1561	Uncharacterized conserved protein YicC, UPF0701 family	290
646766882	245	60.49	1	242	3	230	4.0e-79	287	COG0689	Ribonuclease PH	230
646766883	220	51.5	22	220	1	194	9.0e-61	226	COG0127	Inosine/xanthosine triphosphate pyrophosphatase, all-alpha NTP-PPase family	194
646766884	409	44.27	32	407	34	412	1.0e-107	383	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
646766888	134	37.07	20	134	13	128	1.0e-26	111	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
646766890	406	21.56	5	388	6	380	6.0e-19	88.7	COG2814	Predicted arabinose efflux permease, MFS family	394
646766892	427	60.98	1	427	4	431	0.0e+00	603	COG0001	Glutamate-1-semialdehyde aminotransferase	432
646766893	383	61.07	1	149	1	146	6.0e-58	218	COG0117	Pyrimidine deaminase domain of riboflavin biosynthesis protein RibD	146
646766894	211	41.98	1	209	1	201	4.0e-58	217	COG0307	Riboflavin synthase alpha chain	204
646766897	311	29.26	56	279	2	212	9.0e-31	127	COG3485	Protocatechuate 3,4-dioxygenase beta subunit	226
646766898	96	48.89	1	90	1	90	1.0e-34	137	COG4829	Muconolactone delta-isomerase	98
646766899	378	28.04	5	372	2	370	8.0e-54	204	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
646766901	547	23.72	34	543	5	538	1.0e-54	208	COG2303	Choline dehydrogenase or related flavoprotein	542
646766904	373	32.59	16	361	4	357	1.0e-50	194	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
646766905	377	59.31	1	204	1	203	6.0e-80	291	COG0108	3,4-dihydroxy-2-butanone 4-phosphate synthase	203
646766906	170	48.3	5	147	3	149	2.0e-44	172	COG0054	6,7-dimethyl-8-ribityllumazine synthase (Riboflavin synthase beta chain)	152
646766907	144	43.75	1	137	6	149	9.0e-33	132	COG0781	Transcription termination factor NusB	151
646766908	398	41.67	14	398	2	392	1.0e-96	346	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
646766910	524	53.24	1	524	1	477	0.0e+00	633	COG0043	3-polyprenyl-4-hydroxybenzoate decarboxylase	477
646766911	226	29.06	4	204	3	199	2.0e-12	65.7	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
646766912	321	45.68	1	320	1	324	5.0e-100	357	COG1171	Threonine dehydratase	347
646766915	311	31.05	9	284	13	281	1.0e-39	157	COG5495	Predicted oxidoreductase, contains short-chain dehydrogenase (SDR) and DUF2520 domains	289
646766918	572	38.26	199	517	64	408	4.0e-48	186	COG0840	Methyl-accepting chemotaxis protein	408
646766920	268	47.35	46	266	1	226	2.0e-69	255	COG0220	tRNA G46 methylase TrmB	227
646766921	278	50	1	272	1	270	5.0e-73	267	COG1968	Undecaprenyl pyrophosphate phosphatase UppP	270
646766924	461	38.05	21	451	7	415	3.0e-120	425	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
646766926	67	62.69	1	67	1	67	3.0e-24	103	COG1278	Cold shock protein, CspA family	67
646766940	379	28.16	135	376	98	334	3.0e-26	112	COG0642	Signal transduction histidine kinase	336
646766943	210	26.88	8	193	4	187	2.0e-08	52.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
646766944	297	25	1	295	3	300	9.0e-45	174	COG0492	Thioredoxin reductase	305
646766945	287	28.42	36	210	41	225	3.0e-18	85.7	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
646766948	460	53.42	5	455	6	458	0.0e+00	518	COG1113	L-asparagine transporter and related permeases	462
646766949	295	22.1	62	290	18	282	6.0e-06	45.1	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
646766950	277	43.88	1	277	1	272	7.0e-70	257	COG2362	D-aminopeptidase	274
646766951	361	40.53	18	349	9	344	7.0e-75	274	COG3191	L-aminopeptidase/D-esterase	348
646766952	301	53.02	21	300	8	288	4.0e-77	281	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
646766953	306	49.36	1	304	1	314	6.0e-91	327	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
646766954	520	32.59	14	520	20	553	1.0e-82	301	COG0747	ABC-type transport system, periplasmic component	556
646766955	640	57.14	20	593	5	539	0.0e+00	706	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
646766956	329	48.01	2	328	1	307	4.0e-86	311	COG1446	Isoaspartyl peptidase or L-asparaginase, Ntn-hydrolase superfamily	307
646766957	352	30.74	16	281	5	268	4.0e-41	162	COG1737	DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains	281
646766958	421	23.81	7	405	1	385	1.0e-16	81.4	COG2814	Predicted arabinose efflux permease, MFS family	394
646766959	236	37.04	1	235	3	243	3.0e-53	201	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
646766961	345	23.44	11	330	2	297	8.0e-14	71.5	COG0451	Nucleoside-diphosphate-sugar epimerase	314
646766962	343	35.65	100	329	5	223	5.0e-50	191	COG0543	NAD(P)H-flavin reductase	252
646766963	394	46.1	1	394	7	399	0.0e+00	463	COG4992	Acetylornithine/succinyldiaminopimelate/putrescine aminotransferase	404
646766964	157	27.78	9	136	14	150	1.0e-07	49.6	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
646766965	97	47.42	1	97	8	104	1.0e-23	101	COG4274	Uncharacterized protein, contains GYD domain	104
646766966	240	56.78	5	239	1	236	2.0e-86	312	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
646766967	263	56.92	9	260	1	250	3.0e-91	328	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
646766968	389	38.9	21	367	1	306	8.0e-54	204	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
646766969	316	44.13	1	315	3	297	4.0e-54	204	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
646766970	400	36.94	40	392	1	357	3.0e-53	202	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
646766971	319	66.44	12	302	3	294	3.0e-122	431	COG0761	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH	294
646766972	151	40	9	151	3	141	2.0e-31	128	COG1047	FKBP-type peptidyl-prolyl cis-trans isomerase 2	174
646766973	303	42.2	58	275	6	223	2.0e-62	233	COG2003	DNA repair protein RadC, contains a helix-hairpin-helix DNA-binding motif	224
646766974	77	68.83	1	76	1	77	3.0e-22	96.9	COG0227	Ribosomal protein L28	77
646766975	55	60	4	53	1	50	2.0e-09	54.1	COG0267	Ribosomal protein L33	50
646766976	532	57.03	4	522	9	508	0.0e+00	651	COG0029	Aspartate oxidase	518
646766977	307	47.46	36	307	3	278	5.0e-80	291	COG0157	Nicotinate-nucleotide pyrophosphorylase	280
646766978	380	45.4	32	355	12	324	6.0e-110	391	COG0379	Quinolinate synthase	324
646766979	398	36.5	1	263	30	289	1.0e-78	287	COG1398	Fatty-acid desaturase	289
646766981	419	39.29	85	417	18	353	1.0e-79	290	COG0144	16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family	355
646766982	217	53	2	201	1	200	2.0e-75	275	COG0299	Folate-dependent phosphoribosylglycinamide formyltransferase PurN	200
646766983	349	46.6	19	326	1	304	5.0e-91	328	COG0196	FAD synthase	304
646766984	945	45.75	13	937	4	931	0.0e+00	1128	COG0060	Isoleucyl-tRNA synthetase	933
646766985	168	44.44	7	165	2	160	2.0e-32	131	COG0597	Lipoprotein signal peptidase	167
646766986	405	47.59	6	397	2	391	5.0e-109	388	COG0452	Phosphopantothenoylcysteine synthetase/decarboxylase	392
646766987	338	28.12	23	332	16	334	9.0e-41	161	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
646766988	148	53.38	1	148	6	148	7.0e-50	189	COG0756	dUTPase	148
646766989	765	47.52	1	750	1	785	0.0e+00	868	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
646766990	104	52.88	1	104	4	107	3.0e-31	126	COG2127	ATP-dependent Clp protease adapter protein ClpS	107
646766991	68	69.7	1	66	1	66	6.0e-26	109	COG1278	Cold shock protein, CspA family	67
646766992	418	65.53	12	418	3	406	0.0e+00	603	COG0538	Isocitrate dehydrogenase	407
646766994	171	37.39	50	164	7	121	5.0e-28	117	COG1430	Uncharacterized conserved membrane protein, UPF0127 family	126
646766995	702	67.9	1	702	1	693	0.0e+00	1024	COG0480	Translation elongation factor EF-G, a GTPase	697
646766996	175	44.52	24	169	8	141	1.0e-37	149	COG4101	Uncharacterized protein, RmlC-like cupin domain	142
646766997	339	50.15	4	332	13	339	6.0e-98	351	COG3376	High-affinity nickel permease	342
646766998	414	24.32	39	392	18	341	3.0e-19	90	COG1566	Multidrug resistance efflux pump	352
646766999	797	35.3	44	719	38	696	0.0e+00	531	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
646767000	235	34.78	6	210	1	204	2.0e-40	159	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
646767001	510	19.86	71	499	8	445	4.0e-27	116	COG1538	Outer membrane protein TolC	457
646767002	450	34.96	13	412	1	393	9.0e-96	344	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
646767004	318	42.9	9	311	2	317	1.0e-74	273	COG1181	D-alanine-D-alanine ligase and related ATP-grasp enzymes	317
646767007	1046	29.93	569	1021	1	446	9.0e-68	252	COG0770	UDP-N-acetylmuramyl pentapeptide synthase	451
646767013	557	27.39	35	554	4	551	8.0e-74	271	COG0747	ABC-type transport system, periplasmic component	556
646767014	343	38.22	29	340	3	316	2.0e-76	279	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
646767015	304	41.97	31	303	10	283	8.0e-61	227	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
646767016	729	43.65	23	342	2	316	4.0e-98	352	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
646767019	281	37.68	8	276	6	270	2.0e-65	242	COG0656	Aldo/keto reductase, related to diketogulonate reductase	280
646767020	248	45.34	15	246	1	236	1.0e-53	203	COG2188	DNA-binding transcriptional regulator, GntR family	236
646767022	413	30.91	74	408	22	381	8.0e-49	188	COG0372	Citrate synthase	390
646767024	472	31.03	12	468	2	452	1.0e-88	320	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
646767025	486	20.14	16	432	4	362	2.0e-12	67.2	COG2814	Predicted arabinose efflux permease, MFS family	394
646767026	424	28.7	34	254	17	239	7.0e-29	121	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
646767027	351	29.27	12	173	21	182	9.0e-22	97.8	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
646767028	215	69.79	13	204	3	194	2.0e-80	292	COG0740	ATP-dependent protease ClpP, protease subunit	200
646767029	515	23.73	9	172	7	179	8.0e-10	58.9	COG1432	Uncharacterized conserved protein, LabA/DUF88 family	181
646767032	192	57.07	1	192	2	199	1.0e-73	269	COG0605	Superoxide dismutase	204
646767033	459	49.2	18	454	5	439	2.0e-126	445	COG1570	Exonuclease VII, large subunit	440
646767034	338	47.96	8	318	1	313	2.0e-84	306	COG1663	Tetraacyldisaccharide-1-P 4'-kinase	336
646767035	67	66.67	1	60	1	60	4.0e-18	83	COG2835	Uncharacterized conserved protein YbaR, Trm112 family	60
646767036	264	53.73	8	262	3	242	1.0e-89	322	COG1212	CMP-2-keto-3-deoxyoctulosonic acid synthetase	247
646767037	221	40.89	1	221	1	178	3.0e-47	182	COG0563	Adenylate kinase or related kinase	178
646767038	252	32.7	1	248	1	251	4.0e-32	131	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
646767039	280	39.16	13	275	8	266	2.0e-56	213	COG2912	Regulator of sirC expression, contains transglutaminase-like and TPR domains	269
646767040	516	44.57	1	514	7	517	1.0e-112	400	COG0728	Peptidoglycan biosynthesis protein MviN/MurJ, putative lipid II flippase	518
646767041	92	52.27	1	88	1	88	3.0e-08	50.3	COG0268	Ribosomal protein S20	88
646767043	309	50.97	1	303	1	309	2.0e-118	418	COG0078	Ornithine carbamoyltransferase	310
646767044	360	33.05	12	358	1	284	3.0e-71	262	COG0812	UDP-N-acetylenolpyruvoylglucosamine reductase	291
646767045	161	54.94	1	161	4	165	2.0e-50	191	COG1666	Uncharacterized conserved protein YajQ, UPF0234 family	165
646767046	211	44.78	1	197	3	200	1.0e-45	176	COG0344	Phospholipid biosynthesis protein PlsY, probable glycerol-3-phosphate acyltransferase	200
646767047	163	37.25	10	161	2	154	4.0e-36	144	COG2606	Cys-tRNA(Pro) deacylase, prolyl-tRNA editing enzyme YbaK/EbsC	155
646767048	520	37.48	13	518	2	523	3.0e-97	349	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
646767049	316	58.22	28	316	9	300	2.0e-107	382	COG4974	Site-specific recombinase XerD	300
646767051	424	44.7	36	421	1	335	2.0e-90	326	COG1600	Epoxyqueuosine reductase  QueG (queuosine biosynthesis)	337
646767052	198	40.78	19	197	1	148	4.0e-36	144	COG0802	tRNA A37 threonylcarbamoyladenosine biosynthesis protein TsaE	149
646767053	538	37.13	293	529	30	231	6.0e-52	199	COG0860	N-acetylmuramoyl-L-alanine amidase	231
646767055	291	41.85	4	270	7	270	7.0e-63	234	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
646767056	282	41.99	2	282	27	304	4.0e-66	244	COG3118	Negative regulator of GroEL, contains thioredoxin-like and TPR-like domains	304
646767057	285	54.37	24	283	11	259	3.0e-88	318	COG1179	tRNA A37 threonylcarbamoyladenosine dehydratase	263
646767058	213	60.47	1	213	2	214	2.0e-79	288	COG0259	Pyridoxine/pyridoxamine 5'-phosphate oxidase	214
646767059	404	49.64	107	384	10	283	3.0e-98	352	COG2230	Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases	283
646767060	450	24.43	132	432	2	257	9.0e-26	111	COG1801	Uncharacterized conserved protein YecE, DUF72 family	263
646767061	179	49.71	1	170	5	174	5.0e-63	233	COG0225	Peptide methionine sulfoxide reductase MsrA	174
646767062	169	37.5	9	164	4	160	1.0e-32	132	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
646767063	171	44.52	1	155	1	154	5.0e-33	133	COG1522	DNA-binding transcriptional regulator, Lrp family	154
646767064	220	36.87	1	209	3	218	7.0e-44	170	COG1878	Kynurenine formamidase	218
646767065	416	60.99	4	406	7	407	0.0e+00	528	COG3844	Kynureninase	407
646767066	311	70.23	50	311	1	262	2.0e-109	389	COG3483	Tryptophan 2,3-dioxygenase (vermilion)	262
646767070	245	40	5	243	1	251	4.0e-36	144	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
646767071	514	37.28	1	511	3	501	1.0e-105	377	COG1070	Sugar (pentulose or hexulose) kinase	502
646767072	362	36.39	10	360	1	350	2.0e-73	269	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
646767073	335	54.34	28	335	2	311	1.0e-66	246	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
646767074	506	52.01	1	497	5	500	0.0e+00	607	COG1129	ABC-type sugar transport system, ATPase component	500
646767075	317	36.13	12	312	5	312	1.0e-43	170	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
646767076	325	31.36	164	281	3	120	5.0e-20	92.2	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
646767077	470	36.4	13	462	17	463	1.0e-111	396	COG0246	Mannitol-1-phosphate/altronate dehydrogenases	473
646767078	493	43.03	1	486	5	499	4.0e-122	431	COG1070	Sugar (pentulose or hexulose) kinase	502
646767079	315	40.38	6	315	10	319	5.0e-82	297	COG2390	DNA-binding transcriptional regulator LsrR, DeoR family	321
646767080	369	53.8	1	355	1	338	5.0e-127	447	COG3839	ABC-type sugar transport system, ATPase component	338
646767081	236	33.18	14	227	4	219	1.0e-29	123	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
646767082	291	37.96	25	291	8	281	6.0e-48	184	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
646767083	311	35.17	22	308	7	294	1.0e-53	203	COG1175	ABC-type sugar transport system, permease component	295
646767084	440	27.29	1	435	3	432	4.0e-41	162	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
646767085	259	38.08	3	255	2	249	7.0e-44	170	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
646767086	165	29.5	11	149	3	140	3.0e-25	108	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
646767087	327	27.61	28	309	13	302	4.0e-40	158	COG0803	ABC-type Zn uptake system ZnuABC, Zn-binding component ZnuA	303
646767088	322	35.21	22	286	1	254	2.0e-56	213	COG1121	ABC-type Mn2+/Zn2+ transport system, ATPase component	254
646767089	260	34.48	1	260	8	268	8.0e-31	127	COG1108	ABC-type Mn2+/Zn2+ transport system, permease component	274
646767090	284	36.25	2	284	7	314	6.0e-66	244	COG0627	S-formylglutathione hydrolase FrmB	316
646767092	488	34.62	1	472	4	487	2.0e-80	293	COG1070	Sugar (pentulose or hexulose) kinase	502
646767093	469	48.1	1	442	1	446	8.0e-112	397	COG2233	Xanthine/uracil permease	451
646767094	506	40.04	12	472	1	446	2.0e-71	263	COG1538	Outer membrane protein TolC	457
646767095	1076	54.16	1	1031	2	1009	0.0e+00	1042	COG0841	Multidrug efflux pump subunit AcrB	1009
646767096	407	33.77	1	377	2	371	1.0e-27	117	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
646767097	213	26.09	1	207	2	201	4.0e-12	65.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
646767098	212	30.35	7	182	5	205	5.0e-20	91	COG1335	Nicotinamidase-related amidase	205
646767099	331	38.2	11	330	6	324	1.0e-73	270	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
646767100	244	24.5	1	151	1	143	3.0e-14	72.2	COG3427	Carbon monoxide dehydrogenase subunit G	146
646767101	126	33.64	16	122	19	125	2.0e-27	114	COG2343	Uncharacterized conserved protein, DUF427 family	132
646767103	508	47.99	135	404	72	342	2.0e-63	237	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
646767104	432	33.96	118	432	20	327	5.0e-41	162	COG0642	Signal transduction histidine kinase	336
646767105	220	52.17	1	220	1	229	7.0e-60	223	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
646767106	520	34.77	32	489	7	464	4.0e-82	299	COG2027	D-alanyl-D-alanine carboxypeptidase	470
646767107	335	30.5	9	257	14	270	1.0e-30	127	COG3000	Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily	271
646767108	401	19.54	22	396	5	335	3.0e-17	83.2	COG3240	Phospholipase/lecithinase/hemolysin	370
646767109	350	41.75	18	221	12	210	8.0e-52	197	COG0009	tRNA A37 threonylcarbamoyladenosine synthetase subunit TsaC/SUA5/YrdC	211
646767110	398	46.26	14	386	1	361	1.0e-119	423	COG0026	Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)	375
646767111	172	63.69	11	167	1	155	1.0e-52	199	COG0041	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase	162
646767112	296	34.51	12	292	4	247	3.0e-67	248	COG0152	Phosphoribosylaminoimidazole-succinocarboxamide synthase	247
646767113	354	46.06	1	329	1	286	5.0e-100	357	COG0191	Fructose/tagatose bisphosphate aldolase	286
646767114	478	51.46	1	474	3	477	0.0e+00	559	COG0469	Pyruvate kinase	477
646767115	397	53.27	10	397	6	394	0.0e+00	465	COG0126	3-phosphoglycerate kinase	395
646767116	107	39.25	1	107	1	107	9.0e-12	62.1	COG4392	Branched-chain amino acid transport protein	107
646767117	251	32.59	10	231	9	227	6.0e-30	124	COG1296	Predicted branched-chain amino acid permease (azaleucine resistance)	238
646767118	307	41.64	7	296	1	283	6.0e-73	267	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
646767119	64	52.17	11	55	17	60	2.0e-06	43.8	COG4391	Uncharacterized conserved protein, contains Zn-finger domain	62
646767120	341	37.35	1	330	1	323	6.0e-68	251	COG0859	ADP-heptose:LPS heptosyltransferase	334
646767122	350	44.38	33	344	23	338	7.0e-80	291	COG0429	Predicted hydrolase of the alpha/beta-hydrolase fold	345
646767124	577	34.03	101	576	33	484	4.0e-82	299	COG4783	Putative Zn-dependent protease, contains TPR repeats	484
646767125	159	60.13	1	158	1	157	1.0e-57	215	COG0315	Molybdenum cofactor biosynthesis enzyme	157
646767127	594	14.76	31	416	26	403	1.0e-07	52.1	COG3307	O-antigen ligase	424
646767128	207	34.95	40	142	6	106	2.0e-15	75.8	COG4969	Tfp pilus assembly protein, major pilin PilA	125
646767129	234	24.41	1	232	7	254	2.0e-29	122	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
646767130	293	58.16	1	293	1	289	4.0e-107	381	COG0074	Succinyl-CoA synthetase, alpha subunit	293
646767131	389	59.23	1	388	1	387	0.0e+00	532	COG0045	Succinyl-CoA synthetase, beta subunit	387
646767133	248	36.73	101	243	20	166	5.0e-24	104	COG2137	SOS response regulatory protein OraA/RecX, interacts with RecA	174
646767134	358	66.78	13	292	5	279	5.0e-87	314	COG0468	RecA/RadA recombinase	279
646767135	265	43.48	1	222	1	229	4.0e-57	214	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
646767136	512	33.64	184	502	20	327	2.0e-39	157	COG0642	Signal transduction histidine kinase	336
646767137	552	21.18	9	325	3	289	5.0e-08	53.3	COG2814	Predicted arabinose efflux permease, MFS family	394
646767139	403	22.25	13	391	11	384	7.0e-15	75.2	COG2814	Predicted arabinose efflux permease, MFS family	394
646767140	356	22.69	1	329	3	326	2.0e-21	96.8	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
646767141	270	30.15	9	270	7	258	1.0e-31	129	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
646767142	263	42.23	1	251	3	237	3.0e-66	245	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
646767143	238	29.11	10	216	48	252	8.0e-26	110	COG3665	Uncharacterized conserved protein YcgI, DUF1989 family	264
646767144	213	41.87	16	212	46	247	2.0e-50	192	COG3665	Uncharacterized conserved protein YcgI, DUF1989 family	264
646767147	610	35.11	3	455	1	470	8.0e-79	288	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
646767149	147	33.61	18	136	4	122	2.0e-11	61.9	COG1846	DNA-binding transcriptional regulator, MarR family	126
646767150	512	18.61	6	408	1	340	5.0e-17	82.9	COG2814	Predicted arabinose efflux permease, MFS family	394
646767151	247	38.22	24	245	8	231	2.0e-34	139	COG2186	DNA-binding transcriptional regulator, FadR family	241
646767152	382	41.01	1	362	4	368	9.0e-83	300	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
646767154	309	28.14	9	303	2	286	4.0e-12	65.7	COG1276	Putative copper export protein	289
646767155	111	34.51	1	111	13	125	4.0e-14	69.6	COG2372	Copper-binding protein CopC (methionine-rich)	127
646767156	243	32.26	14	137	5	118	2.0e-14	72.7	COG2863	Cytochrome c553	121
646767157	433	25	158	300	18	149	3.0e-07	50.3	COG2010	Cytochrome c, mono- and diheme variants	150
646767158	206	49.51	5	206	21	224	6.0e-47	180	COG1272	Predicted membrane channel-forming protein YqfA, hemolysin III family	226
646767159	518	43.75	1	467	29	504	4.0e-123	435	COG0513	Superfamily II DNA and RNA helicase	513
646767163	562	42.29	25	561	2	538	0.0e+00	569	COG0405	Gamma-glutamyltranspeptidase	539
646767164	259	43.95	12	259	6	253	2.0e-69	255	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
646767168	509	47.12	1	509	7	521	0.0e+00	502	COG0578	Glycerol-3-phosphate dehydrogenase	532
646767169	499	65.19	1	497	2	498	0.0e+00	792	COG0554	Glycerol kinase	499
646767170	228	32.74	1	217	1	218	1.0e-31	129	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
646767171	239	57.44	31	225	5	198	7.0e-69	253	COG0108	3,4-dihydroxy-2-butanone 4-phosphate synthase	203
646767172	235	25.44	34	146	2	115	2.0e-06	45.8	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
646767173	388	47.01	1	383	11	394	7.0e-73	267	COG2814	Predicted arabinose efflux permease, MFS family	394
646767175	317	30.26	3	301	2	297	1.0e-36	147	COG0583	DNA-binding transcriptional regulator, LysR family	297
646767176	461	50.22	1	451	1	437	0.0e+00	552	COG0621	tRNA A37 methylthiotransferase MiaB	437
646767177	357	47.99	1	348	7	333	3.0e-103	368	COG1702	Phosphate starvation-inducible protein PhoH, predicted ATPase	348
646767178	153	50	34	152	25	150	3.0e-37	147	COG0319	ssRNA-specific RNase YbeY, 16S rRNA maturation enzyme	153
646767179	219	45.98	47	219	10	183	2.0e-44	172	COG3703	Cation transport regulator ChaC	190
646767180	301	49.12	16	295	10	291	2.0e-100	359	COG4535	Mg2+ and Co2+ transporter CorC, contains CBS pair and CorC-HlyC domains	293
646767181	583	30.95	33	580	18	518	3.0e-86	313	COG0815	Apolipoprotein N-acyltransferase	518
646767182	203	29.13	1	201	1	203	2.0e-33	135	COG0625	Glutathione S-transferase	211
646767183	484	29.74	50	466	18	384	2.0e-64	239	COG0006	Xaa-Pro aminopeptidase	384
646767184	423	36.03	21	418	2	383	1.0e-49	190	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
646767185	358	46.63	1	324	1	319	5.0e-94	338	COG0042	tRNA-dihydrouridine synthase	323
646767186	77	48.68	2	77	23	98	2.0e-21	93.5	COG2901	DNA-binding protein Fis (factor for inversion stimulation)	98
646767187	521	64.89	1	521	1	515	0.0e+00	781	COG0138	AICAR transformylase/IMP cyclohydrolase PurH	515
646767189	180	55.06	4	160	1	158	5.0e-51	193	COG0817	Holliday junction resolvasome RuvABC endonuclease subunit	160
646767190	193	47.76	1	191	1	201	2.0e-56	211	COG0632	Holliday junction resolvasome RuvABC DNA-binding subunit	201
646767191	353	69.79	9	339	1	330	0.0e+00	531	COG2255	Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit	332
646767192	324	42.03	50	321	19	292	3.0e-64	239	COG3662	Uncharacterized conserved protein, DUF2236 family	300
646767193	224	40.48	1	210	1	206	2.0e-46	179	COG0406	Broad specificity phosphatase PhoE	208
646767194	152	54.67	1	150	1	145	2.0e-54	204	COG1490	D-Tyr-tRNAtyr deacylase	145
646767195	416	40.4	28	414	11	400	1.0e-114	406	COG0162	Tyrosyl-tRNA synthetase	401
646767196	376	48.51	10	376	7	370	2.0e-102	366	COG2377	1,6-Anhydro-N-acetylmuramate kinase	371
646767197	121	55.45	12	121	1	110	2.0e-39	154	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
646767198	130	60	1	130	1	130	8.0e-45	172	COG0103	Ribosomal protein S9	130
646767199	142	67.83	1	142	1	143	5.0e-54	203	COG0102	Ribosomal protein L13	148
646767200	140	39.57	1	139	2	137	3.0e-32	130	COG1765	Uncharacterized OsmC-related protein	137
646767203	353	61.96	7	353	1	344	0.0e+00	549	COG0418	Dihydroorotase	344
646767204	319	47.84	1	255	1	247	7.0e-78	284	COG0121	Predicted glutamine amidotransferase	252
646767205	241	62.5	1	240	2	240	2.0e-110	391	COG1126	ABC-type polar amino acid transport system, ATPase component	240
646767206	225	39.11	1	225	3	220	5.0e-47	181	COG0765	ABC-type amino acid transport system, permease component	222
646767207	246	34.23	20	241	12	222	1.0e-48	186	COG0765	ABC-type amino acid transport system, permease component	222
646767208	297	30.18	4	272	3	270	1.0e-35	143	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
646767209	440	54.26	29	439	1	411	0.0e+00	519	COG0334	Glutamate dehydrogenase/leucine dehydrogenase	411
646767210	318	28.1	1	273	1	263	8.0e-22	97.8	COG0583	DNA-binding transcriptional regulator, LysR family	297
646767211	462	33.85	18	461	1	435	6.0e-102	364	COG0015	Adenylosuccinate lyase	438
646767212	164	48.75	6	164	1	160	1.0e-56	212	COG3265	Gluconate kinase	161
646767213	461	47.69	8	461	2	442	3.0e-94	339	COG2610	H+/gluconate symporter or related permease	442
646767214	213	45.97	1	210	1	210	3.0e-58	218	COG0800	2-keto-3-deoxy-6-phosphogluconate aldolase	211
646767215	654	39.67	10	609	4	575	0.0e+00	614	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
646767216	281	43.17	1	277	4	281	1.0e-65	242	COG1737	DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains	281
646767217	138	47.18	1	138	8	149	3.0e-33	134	COG1981	Uncharacterized membrane protein	149
646767218	423	56.19	3	422	1	416	0.0e+00	562	COG0014	Gamma-glutamyl phosphate reductase	417
646767219	375	34.06	3	323	1	317	2.0e-59	222	COG1466	DNA polymerase III, delta subunit	334
646767220	183	28.48	1	159	1	161	6.0e-16	77.3	COG2980	Outer membrane lipoprotein LptE/RlpB (LPS assembly)	178
646767221	863	49.03	1	863	1	814	0.0e+00	977	COG0495	Leucyl-tRNA synthetase	814
646767222	143	38.69	1	137	1	135	7.0e-32	129	COG0848	Biopolymer transport protein ExbD	137
646767223	238	41.09	15	215	6	207	7.0e-35	140	COG0811	Biopolymer transport protein ExbB/TolQ	216
646767224	265	56.6	1	264	3	266	2.0e-91	328	COG0289	Dihydrodipicolinate reductase	266
646767225	278	32.5	1	116	7	117	5.0e-20	91.6	COG2913	Outer membrane protein assembly factor BamE, lipoprotein component of the BamABCDE complex	147
646767226	142	49.63	7	141	12	143	3.0e-32	130	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
646767227	170	55.36	1	167	1	168	6.0e-55	206	COG3194	Ureidoglycolate hydrolase (allantoin degradation)	168
646767228	336	56.89	1	333	1	333	0.0e+00	482	COG4266	Allantoicase	334
646767229	442	44.81	1	419	1	415	7.0e-92	331	COG1301	Na+/H+-dicarboxylate symporter	415
646767230	228	30.57	1	220	4	230	2.0e-31	129	COG2186	DNA-binding transcriptional regulator, FadR family	241
646767231	336	62.2	2	335	1	333	4.0e-129	454	COG0057	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase	335
646767232	673	61.32	10	672	7	662	0.0e+00	990	COG0021	Transketolase	663
646767233	137	32.85	11	135	1	131	2.0e-20	91.5	COG2764	Uncharacterized conserved protein PhnB, glyoxalase superfamily	136
646767234	246	44.13	1	244	3	245	4.0e-62	231	COG1385	16S rRNA U1498 N3-methylase RsmE	246
646767236	137	47.54	15	135	30	150	3.0e-31	127	COG4290	Guanyl-specific ribonuclease Sa	152
646767237	779	55.53	21	451	14	432	0.0e+00	544	COG0281	Malic enzyme	432
646767238	333	43.41	1	330	2	317	2.0e-77	282	COG0611	Thiamine monophosphate kinase	317
646767239	191	38.04	30	188	2	160	5.0e-29	120	COG1267	Phosphatidylglycerophosphatase A	160
646767240	166	50	8	163	7	162	3.0e-49	187	COG1546	Nicotinamide mononucleotide (NMN) deamidase PncC	162
646767241	176	46.67	8	172	6	159	1.0e-41	162	COG3542	Predicted sugar epimerase, cupin superfamily	162
646767242	271	28.35	13	269	8	240	3.0e-33	135	COG0284	Orotidine-5'-phosphate decarboxylase	240
646767243	353	28.01	45	336	10	306	2.0e-41	163	COG2017	Galactose mutarotase or related enzyme	308
646767244	313	35.95	12	308	18	307	6.0e-55	207	COG3386	Sugar lactone lactonase YvrE	307
646767245	266	27.67	21	266	2	251	7.0e-36	144	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
646767246	338	36.51	26	337	1	314	7.0e-61	227	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
646767247	520	52.21	1	496	5	500	0.0e+00	610	COG1129	ABC-type sugar transport system, ATPase component	500
646767248	332	25.53	1	326	6	318	1.0e-28	120	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
646767249	260	42.97	3	255	2	251	8.0e-47	180	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
646767250	226	37.31	12	204	1	192	6.0e-41	161	COG0800	2-keto-3-deoxy-6-phosphogluconate aldolase	211
646767251	371	38.56	38	351	3	295	2.0e-49	189	COG3734	2-keto-3-deoxy-galactonokinase	306
646767252	335	40.4	78	323	1	246	3.0e-42	166	COG1414	DNA-binding transcriptional regulator, IclR family	246
646767254	287	36.36	2	283	1	283	4.0e-64	238	COG0169	Shikimate 5-dehydrogenase	283
646767255	712	19.02	32	576	33	576	3.0e-45	177	COG0557	Exoribonuclease R	706
646767256	204	37.63	1	194	1	190	8.0e-54	203	COG3150	Predicted esterase YcpF, UPF0227 family	191
646767257	464	41.16	2	459	9	458	0.0e+00	482	COG0773	UDP-N-acetylmuramate-alanine ligase	459
646767259	186	32.73	59	167	18	124	5.0e-14	71.1	COG0526	Thiol-disulfide isomerase or thioredoxin	127
646767260	151	57.14	2	148	1	146	2.0e-59	221	COG0757	3-dehydroquinate dehydratase	146
646767261	155	52.35	6	154	1	138	4.0e-28	117	COG0511	Biotin carboxyl carrier protein	140
646767262	454	64.81	1	447	1	448	0.0e+00	616	COG0439	Biotin carboxylase	449
646767263	300	45.57	1	297	2	300	3.0e-80	292	COG2264	Ribosomal protein L11 methylase PrmA	300
646767265	166	60.13	1	158	1	158	1.0e-60	225	COG2077	Peroxiredoxin	158
646767266	312	26.92	36	307	26	311	6.0e-34	138	COG0524	Sugar or nucleoside kinase, ribokinase family	311
646767267	158	38.96	6	158	3	154	9.0e-24	103	COG3133	Outer membrane lipoprotein SlyB	154
646767270	411	38.35	72	409	7	339	2.0e-103	369	COG0208	Ribonucleotide reductase beta subunit, ferritin-like domain	348
646767271	1003	35.94	188	927	1	652	0.0e+00	590	COG0209	Ribonucleotide reductase alpha subunit	696
646767274	307	42.39	62	304	39	265	1.0e-46	180	COG4137	ABC-type uncharacterized transport system, permease component	265
646767275	455	56.92	1	454	1	448	0.0e+00	589	COG0541	Signal recognition particle GTPase	451
646767276	183	34.5	12	181	7	176	1.0e-47	182	COG0634	Hypoxanthine-guanine phosphoribosyltransferase	178
646767277	199	42.79	1	199	3	203	1.0e-34	139	COG2095	Small neutral amino acid transporter SnatA, MarC family	203
646767278	578	44.54	1	564	1	494	0.0e+00	569	COG0442	Prolyl-tRNA synthetase	500
646767279	249	18.63	3	157	5	156	5.0e-07	48.4	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
646767281	372	53.12	5	372	3	369	3.0e-125	441	COG0263	Glutamate 5-kinase	369
646767282	373	59.72	1	354	1	353	0.0e+00	501	COG0536	GTPase involved in cell partioning and DNA repair	369
646767283	86	73.26	1	86	1	85	7.0e-29	118	COG0211	Ribosomal protein L27	87
646767284	103	54.37	1	103	1	103	5.0e-32	129	COG0261	Ribosomal protein L21	103
646767285	330	39.51	14	330	3	322	3.0e-77	281	COG0142	Geranylgeranyl pyrophosphate synthase	322
646767287	432	43.54	5	419	1	415	1.0e-128	453	COG4536	Mg2+ and Co2+ transporter CorB, contains DUF21, CBS pair, and CorC-HlyC domains	423
646767288	418	52.48	13	416	103	499	0.0e+00	472	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
646767289	412	39.2	17	412	3	396	3.0e-85	309	COG1459	Type II secretory pathway, component PulF	397
646767290	313	41.18	43	313	6	251	4.0e-37	148	COG1989	Prepilin signal peptidase PulO (type II secretory pathway) or related peptidase	254
646767291	204	41.41	1	198	2	197	2.0e-48	185	COG0237	Dephospho-CoA kinase	201
646767292	251	34.94	1	249	1	244	1.0e-74	272	COG4582	Cell division protein ZapD, interacts with FtsZ	244
646767293	67	54.39	2	58	5	61	4.0e-14	69.7	COG3024	Endogenous inhibitor of DNA gyrase, YacG/DUF329 family	65
646767294	148	32.37	15	145	2	138	3.0e-13	68.1	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
646767295	289	59.01	3	285	5	280	4.0e-108	384	COG2607	Predicted ATPase, AAA+ superfamily	287
646767296	413	47.26	13	413	12	404	0.0e+00	473	COG1364	N-acetylglutamate synthase (N-acetylornithine aminotransferase)	404
646767297	940	56.67	4	933	3	822	0.0e+00	1089	COG0653	Preprotein translocase subunit SecA (ATPase, RNA helicase)	822
646767300	305	60.27	1	296	1	295	3.0e-123	435	COG0774	UDP-3-O-acyl-N-acetylglucosamine deacetylase	300
646767301	167	47.31	1	166	2	165	9.0e-57	212	COG0678	Peroxiredoxin	165
646767302	400	54.52	7	324	6	325	2.0e-92	332	COG0206	Cell division GTPase FtsZ	338
646767303	410	49.76	8	410	7	418	2.0e-130	459	COG0849	Cell division ATPase FtsA	418
646767304	250	25.94	14	247	36	267	3.0e-32	132	COG1589	Cell division septal protein FtsQ	269
646767305	313	45.28	8	311	1	317	2.0e-75	276	COG1181	D-alanine-D-alanine ligase and related ATP-grasp enzymes	317
646767306	467	50.96	1	466	3	458	0.0e+00	550	COG0773	UDP-N-acetylmuramate-alanine ligase	459
646767307	374	42.82	7	360	1	355	3.0e-93	335	COG0707	UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase	357
646767310	425	38.89	52	425	14	381	1.0e-85	310	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
646767311	512	41.15	5	506	1	448	9.0e-122	430	COG0771	UDP-N-acetylmuramoylalanine-D-glutamate ligase	448
646767312	389	38.83	20	389	1	316	2.0e-52	200	COG0472	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase	319
646767313	470	42.28	11	454	9	447	2.0e-111	396	COG0770	UDP-N-acetylmuramyl pentapeptide synthase	451
646767314	520	42.36	31	511	13	475	5.0e-111	395	COG0769	UDP-N-acetylmuramyl tripeptide synthase	475
646767315	621	34.78	15	569	5	597	5.0e-119	422	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
646767316	116	28.38	1	74	20	93	6.0e-14	69.6	COG3116	Cell division protein FtsL, interacts with FtsB, FtsL and FtsQ	105
646767317	313	52.2	1	312	1	313	2.0e-107	382	COG0275	16S rRNA C1402 N4-methylase RsmH	314
646767318	142	38.78	1	142	1	146	1.0e-37	148	COG2001	MraZ, DNA-binding transcriptional regulator and inhibitor of RsmH methyltransferase activity	146
646767319	212	40	3	212	1	204	2.0e-49	188	COG2941	Demethoxyubiquinone hydroxylase, CLK1/Coq7/Cat5 family	204
646767320	398	23.65	1	398	1	354	3.0e-43	169	COG3203	Outer membrane protein (porin)	354
646767321	557	37.14	13	554	1	523	0.0e+00	461	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
646767322	692	33.2	12	692	48	764	0.0e+00	475	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
646767323	398	46.23	1	395	2	390	1.0e-122	433	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
646767329	258	46.51	1	255	2	257	2.0e-57	215	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
646767330	566	22.04	55	528	13	446	2.0e-31	131	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
646767331	263	40.23	1	260	2	257	3.0e-49	188	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
646767332	153	32.14	11	146	1	139	4.0e-19	87.8	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
646767333	434	60	10	431	15	436	0.0e+00	546	COG1541	Phenylacetate-coenzyme A ligase PaaK, adenylate-forming domain family	438
646767334	372	39.13	30	371	8	366	7.0e-85	307	COG2821	Membrane-bound lytic murein transglycosylase	373
646767336	124	51.61	1	124	3	126	1.0e-43	168	COG2967	Uncharacterized protein affecting Mg2+/Co2+ transport	126
646767337	254	59.11	28	252	1	220	1.0e-87	316	COG0036	Pentose-5-phosphate-3-epimerase	220
646767338	238	36.24	17	234	6	220	9.0e-40	157	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
646767339	497	46.06	18	494	1	462	0.0e+00	489	COG0147	Anthranilate/para-aminobenzoate synthases component I	462
646767340	205	62.77	1	187	3	190	5.0e-83	300	COG0512	Anthranilate/para-aminobenzoate synthase component II	191
646767341	343	52.51	2	340	1	338	5.0e-115	408	COG0547	Anthranilate phosphoribosyltransferase	338
646767342	261	51.75	5	261	1	254	8.0e-80	290	COG0134	Indole-3-glycerol phosphate synthase	254
646767344	274	57.71	44	267	1	223	5.0e-89	320	COG0692	Uracil DNA glycosylase	223
646767345	198	45.77	1	198	1	201	4.0e-60	224	COG1182	FMN-dependent NADH-azoreductase	202
646767346	596	44.12	4	589	1	544	0.0e+00	503	COG3975	Predicted metalloprotease, contains C-terminal PDZ domain	558
646767347	241	20.82	1	239	1	241	9.0e-18	84.1	COG1651	Protein-disulfide isomerase	244
646767348	390	36.67	6	390	1	384	2.0e-60	226	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
646767350	364	61.02	1	364	1	372	0.0e+00	502	COG0012	Ribosome-binding ATPase YchF, GTP1/OBG family	372
646767352	441	28.02	6	436	8	433	1.0e-46	181	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
646767353	294	43	2	292	1	292	7.0e-58	217	COG1175	ABC-type sugar transport system, permease component	295
646767354	281	39.49	5	277	7	276	8.0e-54	204	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
646767355	362	49.72	1	356	1	338	9.0e-124	437	COG3839	ABC-type sugar transport system, ATPase component	338
646767356	554	48.62	3	536	1	530	0.0e+00	571	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
646767358	207	23.27	1	189	2	197	9.0e-18	83.8	COG1011	FMN phosphatase YigB, HAD superfamily	229
646767359	604	30.79	171	562	2	384	1.0e-54	208	COG0006	Xaa-Pro aminopeptidase	384
646767361	236	35.53	1	226	1	227	2.0e-35	142	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
646767362	428	45.84	1	421	1	410	1.0e-127	450	COG0373	Glutamyl-tRNA reductase	414
646767363	360	63.64	1	359	1	363	0.0e+00	533	COG0216	Protein chain release factor A	363
646767364	295	44.4	17	292	10	278	2.0e-58	219	COG2890	Methylase of polypeptide chain release factors	280
646767365	103	61.17	1	103	2	104	2.0e-42	163	COG0278	Glutaredoxin-related protein	105
646767366	200	60.21	9	197	2	191	4.0e-75	273	COG0163	3-polyprenyl-4-hydroxybenzoate decarboxylase	191
646767367	261	40.91	1	259	6	267	4.0e-60	224	COG3384	Aromatic ring-opening dioxygenase, catalytic subunit, LigB family	268
646767368	531	28.87	14	442	20	442	1.0e-36	148	COG0531	Amino acid transporter	466
646767369	67	61.19	1	67	1	67	1.0e-23	100	COG1278	Cold shock protein, CspA family	67
646767370	416	24.07	4	415	8	417	4.0e-45	175	COG0443	Molecular chaperone DnaK (HSP70)	579
646767371	507	21.36	68	477	43	394	2.0e-15	77.6	COG2814	Predicted arabinose efflux permease, MFS family	394
646767372	205	30.81	17	168	2	183	3.0e-18	85.4	COG0778	Nitroreductase	207
646767373	427	21.95	12	426	24	447	2.0e-11	64.4	COG2271	Sugar phosphate permease	448
646767374	215	23.71	17	208	3	191	3.0e-08	52.3	COG1309	DNA-binding transcriptional regulator, AcrR family	201
646767375	184	54.75	6	184	10	188	1.0e-58	219	COG3310	Uncharacterized protein	196
646767379	422	35.18	9	417	5	408	2.0e-110	392	COG2081	Predicted flavoprotein YhiN	408
646767380	374	26.38	64	313	1	230	9.0e-20	91.6	COG2890	Methylase of polypeptide chain release factors	280
646767381	213	33.85	8	202	16	191	2.0e-20	92.5	COG5516	Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding	196
646767383	284	23.32	9	284	5	281	9.0e-17	80.9	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
646767385	165	43.2	1	165	3	155	3.0e-44	171	COG2969	Stringent starvation protein B	155
646767386	203	39.6	2	193	1	201	7.0e-30	123	COG0625	Glutathione S-transferase	211
646767387	251	35.43	1	251	1	250	4.0e-55	208	COG2857	Cytochrome c1	250
646767388	459	47.21	10	438	5	372	3.0e-88	319	COG1290	Cytochrome b subunit of the bc complex	381
646767389	232	32.51	31	232	4	173	4.0e-29	121	COG0723	Rieske Fe-S protein	177
646767390	248	38.65	1	248	1	250	2.0e-59	222	COG0327	Putative GTP cyclohydrolase 1 type 2, NIF3 family	250
646767391	406	47.49	55	391	26	347	1.0e-71	264	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
646767392	261	45.06	7	257	1	253	9.0e-61	226	COG0805	Sec-independent protein secretion pathway component TatC	255
646767393	180	33.33	1	72	1	72	5.0e-13	67.7	COG1826	Sec-independent protein translocase protein TatA	94
646767394	80	28.21	1	78	1	78	7.0e-13	65.8	COG1826	Sec-independent protein translocase protein TatA	94
646767395	121	43.52	6	113	2	104	8.0e-26	108	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
646767396	131	38.94	19	131	14	124	2.0e-24	104	COG3671	Uncharacterized membrane protein	125
646767397	131	50.53	19	113	1	91	3.0e-23	101	COG0140	Phosphoribosyl-ATP pyrophosphohydrolase	92
646767398	136	60.95	9	113	7	111	3.0e-46	177	COG0139	Phosphoribosyl-AMP cyclohydrolase	111
646767399	257	69.02	3	257	2	255	2.0e-114	405	COG0107	Imidazole glycerol phosphate synthase subunit HisF	256
646767400	250	50.62	1	243	2	240	2.0e-80	292	COG0106	Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase	241
646767401	213	50.7	3	213	2	204	3.0e-73	267	COG0118	Imidazoleglycerol phosphate synthase glutamine amidotransferase subunit HisH	204
646767402	195	62.56	1	195	3	195	8.0e-82	296	COG0131	Imidazoleglycerol phosphate dehydratase HisB	195
646767403	356	40.9	4	356	2	353	3.0e-76	278	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
646767404	444	53.59	21	437	12	422	0.0e+00	531	COG0141	Histidinol dehydrogenase	425
646767405	232	47.17	17	224	3	212	3.0e-57	215	COG0040	ATP phosphoribosyltransferase	290
646767406	420	66.98	1	418	1	421	0.0e+00	617	COG0766	UDP-N-acetylglucosamine enolpyruvyl transferase	421
646767407	79	48.68	3	77	1	76	3.0e-23	99	COG5007	Acid stress-induced BolA-like protein IbaG/YrbA, predicted regulator of iron metabolism	80
646767408	254	22.33	26	240	43	247	6.0e-10	58.2	COG1682	ABC-type polysaccharide/polyol phosphate export permease	263
646767409	310	41.5	1	302	2	293	6.0e-74	271	COG1131	ABC-type multidrug transport system, ATPase component	293
646767410	106	22.78	18	95	20	98	6.0e-08	49.1	COG3113	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, MlaB component, contains STAS domain	99
646767411	210	30.39	1	201	4	202	2.0e-37	148	COG2854	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic MlaC component	202
646767412	354	43.59	20	248	10	242	2.0e-67	249	COG2853	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, lipoprotein component MlaA	250
646767414	255	46.46	1	254	11	263	2.0e-60	225	COG0767	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, permease component MlaE	267
646767415	274	58.46	4	262	3	262	4.0e-100	357	COG1127	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, ATPase component MlaF	263
646767416	367	39.59	169	365	14	206	2.0e-41	163	COG0352	Thiamine monophosphate synthase	211
646767417	271	55.77	6	265	4	262	4.0e-97	347	COG2022	Thiamin biosynthesis thiazole synthase ThiGH, ThiG subunit	262
646767418	78	47.06	12	78	1	68	1.0e-12	64.5	COG2104	Sulfur carrier protein ThiS (thiamine biosynthesis)	68
646767419	376	26.29	8	364	6	385	1.0e-21	98.1	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
646767420	583	43.74	20	583	30	595	0.0e+00	589	COG4178	ABC-type uncharacterized transport system, permease and ATPase components	604
646767423	247	40.87	5	233	3	229	4.0e-53	201	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
646767424	223	30.13	5	220	2	230	1.0e-33	136	COG2063	Flagellar basal body L-ring protein FlgH	230
646767428	246	40.52	3	233	1	229	2.0e-53	202	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
646767429	435	26	142	433	41	332	3.0e-30	126	COG0642	Signal transduction histidine kinase	336
646767430	291	24.4	47	286	3	248	5.0e-17	82	COG2365	Protein tyrosine/serine phosphatase	249
646767431	489	43.55	22	482	1	451	0.0e+00	489	COG0493	NADPH-dependent glutamate synthase beta chain or related oxidoreductase	457
646767432	1592	57.09	748	1266	1	485	0.0e+00	659	COG0069	Glutamate synthase domain 2	485
646767433	235	19.29	1	140	1	136	3.0e-08	52.2	COG1943	REP element-mobilizing transposase RayT	136
646767434	241	29.83	4	241	3	213	4.0e-34	138	COG3047	Outer membrane protein W	213
646767435	126	35.42	32	124	9	104	8.0e-12	62.6	COG4575	Membrane-anchored ribosome-binding protein, inhibits growth in stationary phase, ElaB/YqjD/DUF883 family	104
646767436	424	46.88	55	419	9	409	6.0e-104	371	COG0232	dGTP triphosphohydrolase	412
646767437	361	60.11	4	353	1	349	2.0e-130	458	COG0337	3-dehydroquinate synthetase	360
646767438	168	56.33	1	158	11	167	4.0e-51	193	COG0703	Shikimate kinase	172
646767443	798	51.49	21	743	1	736	0.0e+00	897	COG5009	Membrane carboxypeptidase/penicillin-binding protein	797
646767444	106	43.4	1	104	1	106	5.0e-27	112	COG1965	Iron-binding protein CyaY, frataxin homolog	106
646767446	420	47.18	10	394	8	394	2.0e-116	412	COG0019	Diaminopimelate decarboxylase	394
646767447	233	43.65	37	233	10	201	3.0e-40	158	COG2717	Periplasmic DMSO/TMAO reductase YedYZ, heme-binding membrane subunit	209
646767448	331	41.34	30	303	4	271	9.0e-66	243	COG2041	Periplasmic DMSO/TMAO reductase YedYZ, molybdopterin-dependent catalytic subunit	271
646767449	402	32.29	131	401	1	281	2.0e-30	126	COG0755	ABC-type transport system involved in cytochrome c biogenesis, permease component	281
646767450	736	23.17	27	675	1	473	4.0e-72	266	COG1333	Cytochrome c biogenesis protein ResB	478
646767451	217	38.89	13	138	4	121	5.0e-20	91.2	COG2863	Cytochrome c553	121
646767452	220	44.17	3	208	2	199	3.0e-61	228	COG0218	GTP-binding protein EngB required for normal cell division	200
646767453	332	59.52	1	331	2	330	0.0e+00	513	COG0113	Delta-aminolevulinic acid dehydratase, porphobilinogen synthase	330
646767454	626	38.7	13	622	1	568	2.0e-125	443	COG4232	Thiol:disulfide interchange protein	569
646767455	110	37.25	4	104	2	103	5.0e-23	99.5	COG1324	Uncharacterized protein involved in tolerance to divalent cations	104
646767456	130	73.28	1	116	1	116	3.0e-45	173	COG0203	Ribosomal protein L17	116
646767457	325	53.8	5	320	1	313	5.0e-96	344	COG0202	DNA-directed RNA polymerase, alpha subunit/40 kD subunit	317
646767458	207	58.65	1	207	1	205	1.0e-60	225	COG0522	Ribosomal protein S4 or related protein	205
646767459	134	69.05	9	134	4	129	5.0e-46	176	COG0100	Ribosomal protein S11	129
646767460	121	59.5	1	120	1	121	8.0e-39	152	COG0099	Ribosomal protein S13	121
646767461	38	68.42	1	38	1	38	1.0e-05	41.7	COG0257	Ribosomal protein L36	38
646767462	72	68.06	1	72	1	72	2.0e-25	107	COG0361	Translation initiation factor IF-1	75
646767463	448	51.28	12	436	11	432	1.0e-127	450	COG0201	Preprotein translocase subunit SecY	436
646767464	144	54.05	1	142	1	148	2.0e-30	124	COG0200	Ribosomal protein L15	152
646767465	60	52.83	6	58	1	53	5.0e-12	62.8	COG1841	Ribosomal protein L30/L7E	55
646767466	172	60.12	11	172	18	180	2.0e-55	208	COG0098	Ribosomal protein S5	181
646767467	121	50.82	1	121	6	125	5.0e-27	112	COG0256	Ribosomal protein L18	125
646767468	176	51.41	1	175	1	176	1.0e-55	209	COG0097	Ribosomal protein L6P/L9E	178
646767469	131	61.07	1	130	1	131	4.0e-46	176	COG0096	Ribosomal protein S8	132
646767470	101	60.34	44	101	4	61	6.0e-15	72.2	COG0199	Ribosomal protein S14	61
646767471	179	65.92	1	179	1	179	3.0e-74	271	COG0094	Ribosomal protein L5	180
646767472	102	53.85	1	101	2	104	1.0e-16	78.4	COG0198	Ribosomal protein L24	104
646767473	122	72.13	1	122	1	122	5.0e-49	186	COG0093	Ribosomal protein L14	122
646767474	90	63.29	10	88	8	86	4.0e-23	99.5	COG0186	Ribosomal protein S17	87
646767475	64	49.21	2	64	4	66	3.0e-07	46.8	COG0255	Ribosomal protein L29	69
646767476	138	61.31	1	135	2	138	7.0e-46	176	COG0197	Ribosomal protein L16/L10AE	146
646767477	268	56.65	12	242	1	233	6.0e-76	277	COG0092	Ribosomal protein S3	233
646767478	109	58.33	1	108	9	116	1.0e-32	131	COG0091	Ribosomal protein L22	120
646767479	91	70.33	1	91	1	91	1.0e-37	147	COG0185	Ribosomal protein S19	93
646767480	275	60	1	274	1	275	3.0e-107	381	COG0090	Ribosomal protein L2	275
646767481	104	56.38	11	103	1	94	5.0e-21	92.6	COG0089	Ribosomal protein L23	94
646767482	206	42.86	1	206	2	211	1.0e-54	206	COG0088	Ribosomal protein L4	214
646767483	219	54.13	2	218	1	218	5.0e-71	260	COG0087	Ribosomal protein L3	218
646767484	103	71.84	1	103	1	103	1.0e-37	147	COG0051	Ribosomal protein S10	104
646767485	396	84.85	1	396	1	394	0.0e+00	715	COG0050	Translation elongation factor EF-Tu, a GTPase	394
646767486	700	66.71	1	700	1	693	0.0e+00	1020	COG0480	Translation elongation factor EF-G, a GTPase	697
646767487	156	62.16	2	149	1	148	2.0e-53	201	COG0049	Ribosomal protein S7	148
646767488	126	78.86	1	123	7	129	1.0e-49	188	COG0048	Ribosomal protein S12	129
646767489	615	47.95	7	614	8	586	0.0e+00	697	COG0514	Superfamily II DNA helicase RecQ	590
646767490	1412	48.8	13	858	1	808	0.0e+00	869	COG0086	DNA-directed RNA polymerase, beta' subunit/160 kD subunit	808
646767492	125	67.2	1	125	1	124	8.0e-24	102	COG0222	Ribosomal protein L7/L12	124
646767493	167	44.38	1	167	1	169	2.0e-32	131	COG0244	Ribosomal protein L10	175
646767494	232	59.91	1	226	1	227	8.0e-80	290	COG0081	Ribosomal protein L1	228
646767495	143	69.01	2	143	1	141	5.0e-52	196	COG0080	Ribosomal protein L11	141
646767496	185	56.57	11	185	3	177	6.0e-54	203	COG0250	Transcription antitermination factor NusG	178
646767497	111	37.14	34	103	2	71	4.0e-10	56.6	COG0690	Preprotein translocase subunit SecE	73
646767499	396	84.85	1	396	1	394	0.0e+00	715	COG0050	Translation elongation factor EF-Tu, a GTPase	394
646767508	426	19.73	204	415	3	204	2.0e-10	60.7	COG2755	Lysophospholipase L1 or related esterase	216
646767509	540	43.02	5	536	1	485	0.0e+00	507	COG2509	Uncharacterized FAD-dependent dehydrogenase	486
646767510	332	46.82	32	297	1	265	3.0e-90	325	COG3396	1,2-phenylacetyl-CoA epoxidase, catalytic subunit	265
646767511	94	61.17	2	94	7	109	4.0e-31	126	COG3460	1,2-phenylacetyl-CoA epoxidase, PaaB subunit	117
646767512	270	40.53	10	270	20	265	8.0e-57	214	COG3396	1,2-phenylacetyl-CoA epoxidase, catalytic subunit	265
646767513	194	30.91	13	120	3	111	9.0e-18	83.4	COG2151	Metal-sulfur cluster biosynthetic enzyme	111
646767514	362	29.59	5	298	4	266	3.0e-49	189	COG1018	Ferredoxin-NADP reductase	266
646767516	203	22.39	1	201	2	201	3.0e-07	48.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
646767518	165	45.73	1	164	1	154	2.0e-37	148	COG1522	DNA-binding transcriptional regulator, Lrp family	154
646767519	365	57.77	1	364	9	362	0.0e+00	475	COG3185	4-hydroxyphenylpyruvate dioxygenase and related hemolysins	363
646767521	1199	34.76	30	724	1	637	0.0e+00	668	COG4231	TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit	640
646767522	760	55.73	1	432	13	432	0.0e+00	561	COG0281	Malic enzyme	432
646767523	414	25.13	16	396	4	383	6.0e-20	92.2	COG2814	Predicted arabinose efflux permease, MFS family	394
646767524	228	31.19	14	213	7	200	1.0e-35	143	COG0461	Orotate phosphoribosyltransferase	201
646767525	229	32.24	5	217	1	211	4.0e-39	155	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
646767526	198	40.57	25	198	7	173	3.0e-35	141	COG1881	Uncharacterized conserved protein, phosphatidylethanolamine-binding protein (PEBP) family	174
646767527	190	29.86	1	187	3	207	4.0e-25	107	COG0655	Multimeric flavodoxin WrbA	207
646767528	315	31.75	1	314	1	343	2.0e-71	262	COG0002	N-acetyl-gamma-glutamylphosphate reductase	349
646767529	211	37.26	1	211	1	208	2.0e-28	118	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
646767530	289	42.66	1	282	1	284	4.0e-53	201	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
646767531	269	38.96	108	259	2	155	8.0e-36	144	COG1656	Uncharacterized conserved protein, contains PIN domain	165
646767534	250	36.07	9	250	2	244	5.0e-42	164	COG1414	DNA-binding transcriptional regulator, IclR family	246
646767535	309	27.21	6	294	3	287	7.0e-06	44.9	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
646767540	199	28.25	17	186	30	206	3.0e-08	52	COG0705	Membrane associated serine protease, rhomboid family	228
646767541	605	52.81	1	605	1	597	0.0e+00	768	COG0449	Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains	597
646767542	453	56.99	1	453	3	460	0.0e+00	608	COG1207	Bifunctional protein GlmU, N-acetylglucosamine-1-phosphate-uridyltransferase/glucosamine-1-phosphate-acetyltransferase	460
646767543	333	34.39	43	292	1	246	3.0e-52	198	COG0037	tRNA(Ile)-lysidine synthase TilS/MesJ	298
646767544	131	25.83	13	131	2	120	1.0e-19	88.7	COG1539	Dihydroneopterin aldolase	121
646767545	275	31.5	20	260	6	250	3.0e-24	106	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
646767546	400	40.53	23	395	1	370	9.0e-88	317	COG1565	SAM-dependent methyltransferase, MidA family	370
646767548	410	34.01	1	389	23	399	5.0e-70	258	COG0617	tRNA nucleotidyltransferase/poly(A) polymerase	412
646767549	217	29.72	1	206	1	208	5.0e-20	91.4	COG0625	Glutathione S-transferase	211
646767550	317	29.92	5	258	2	244	3.0e-25	109	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
646767551	668	28.95	369	661	1	296	2.0e-26	114	COG0741	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)	296
646767552	180	36.46	2	175	11	188	6.0e-28	116	COG0212	5-formyltetrahydrofolate cyclo-ligase	191
646767553	170	44.58	5	170	34	199	4.0e-44	171	COG5631	Predicted transcription regulator, contains HTH domain, MarR family	199
646767554	217	55.77	6	210	1	208	1.0e-71	262	COG2049	Allophanate hydrolase subunit 1	223
646767555	350	46.59	2	338	1	314	2.0e-101	362	COG1984	Allophanate hydrolase subunit 2	314
646767556	250	60.8	1	245	2	251	4.0e-94	337	COG1540	Lactam utilization protein B (function unknown)	252
646767557	257	59.11	5	229	1	224	7.0e-80	290	COG3819	Uncharacterized membrane protein	229
646767558	318	55.03	1	318	1	313	3.0e-98	352	COG3817	Uncharacterized membrane protein	313
646767559	422	28.62	150	421	32	297	8.0e-27	115	COG3735	Uncharacterized conserved protein YbaP, TraB family	299
646767560	339	45.07	18	321	4	263	2.0e-95	342	COG4608	ABC-type oligopeptide transport system, ATPase component	309
646767561	334	52.65	4	318	1	315	4.0e-117	414	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
646767562	305	52.48	23	303	12	288	7.0e-73	267	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
646767563	336	49.1	1	334	1	315	7.0e-95	340	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
646767564	543	35.89	9	543	13	553	3.0e-94	339	COG0747	ABC-type transport system, periplasmic component	556
646767565	552	34.72	22	549	17	550	5.0e-95	341	COG0747	ABC-type transport system, periplasmic component	556
646767566	276	43.73	2	276	13	289	5.0e-74	271	COG0685	5,10-methylenetetrahydrofolate reductase	291
646767567	117	49.55	1	110	2	112	4.0e-15	73.2	COG1950	Uncharacterized membrane protein YvlD, DUF360 family	120
646767568	472	55.24	10	464	2	420	0.0e+00	639	COG0499	S-adenosylhomocysteine hydrolase	420
646767569	241	47.71	22	239	10	227	2.0e-54	205	COG1346	Putative effector of murein hydrolase	230
646767570	163	34.13	26	151	3	128	1.0e-22	99.8	COG1380	Putative effector of murein hydrolase LrgA, UPF0299 family	128
646767571	316	32.23	1	297	1	297	4.0e-35	142	COG0583	DNA-binding transcriptional regulator, LysR family	297
646767572	541	42.8	1	531	6	538	4.0e-121	428	COG2303	Choline dehydrogenase or related flavoprotein	542
646767573	562	30.87	78	457	26	390	3.0e-48	186	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
646767574	472	30.58	5	447	32	470	1.0e-81	297	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
646767580	122	40.45	1	88	1	88	4.0e-18	83.7	COG2257	Type III secretion system substrate exporter, FlhB-like	92
646767583	144	41.73	4	130	2	123	2.0e-24	104	COG1516	Flagellin-specific chaperone FliS	132
646767584	111	35.58	8	111	9	105	8.0e-10	55.7	COG1677	Flagellar hook-basal body complex protein FliE	105
646767585	598	41.76	50	597	7	545	0.0e+00	461	COG1766	Flagellar biosynthesis/type III secretory pathway M-ring protein FliF/YscJ	545
646767586	331	48.77	5	329	13	338	2.0e-86	312	COG1536	Flagellar motor switch protein FliG	339
646767587	227	31.17	1	227	1	230	4.0e-27	115	COG1317	Flagellar biosynthesis/type III secretory pathway protein FliH	234
646767588	546	56.73	90	542	2	441	0.0e+00	587	COG1157	Flagellar biosynthesis/type III secretory pathway ATPase	441
646767589	149	32.65	1	147	1	147	1.0e-16	79.6	COG2882	Flagellar biosynthesis chaperone FliJ	148
646767590	510	19.49	106	480	3	391	1.0e-07	52	COG3144	Flagellar hook-length control protein FliK	417
646767602	438	22.71	144	417	27	291	2.0e-14	74.1	COG4974	Site-specific recombinase XerD	300
646767603	166	31.65	9	166	8	159	3.0e-22	98	COG1580	Flagellar basal body-associated protein FliL	159
646767604	332	45.03	5	324	3	323	7.0e-94	337	COG1868	Flagellar motor switch protein FliM	332
646767605	154	45.61	33	142	23	136	3.0e-21	94.7	COG1886	Flagellar motor switch/type III secretory pathway protein FliN	136
646767606	171	29.46	30	156	1	129	3.0e-17	81.1	COG3190	Flagellar biogenesis protein FliO	137
646767607	269	53.5	26	268	5	247	9.0e-76	277	COG1338	Flagellar biosynthetic protein FliP	248
646767608	89	51.69	1	89	1	89	6.0e-17	79	COG1987	Flagellar biosynthesis protein FliQ	89
646767609	260	39.69	4	260	3	258	1.0e-43	170	COG1684	Flagellar biosynthesis protein FliR	258
646767610	408	21.92	1	406	1	357	9.0e-20	91.7	COG1344	Flagellin and related hook-associated protein FlgL	360
646767611	664	31.33	1	475	2	472	4.0e-54	206	COG1256	Flagellar hook-associated protein FlgK	552
646767612	263	30.17	37	263	6	231	6.0e-33	134	COG5581	c-di-GMP-binding flagellar brake protein YcgR, contains PilZNR and PilZ domains	233
646767613	332	42.58	178	332	36	183	6.0e-36	144	COG1705	Flagellum-specific peptidoglycan hydrolase FlgJ	201
646767614	389	52.79	13	389	4	365	3.0e-113	401	COG1706	Flagellar basal body P-ring protein FlgI	365
646767615	215	42.41	3	212	7	230	1.0e-49	189	COG2063	Flagellar basal body L-ring protein FlgH	230
646767616	262	56.06	1	260	1	263	2.0e-81	295	COG4786	Flagellar basal body rod protein FlgG	265
646767617	252	54.65	1	252	1	251	2.0e-73	269	COG4787	Flagellar basal body rod protein FlgF	251
646767619	235	40.85	23	235	12	222	2.0e-26	112	COG1843	Flagellar hook assembly protein FlgD	222
646767620	141	59.42	3	140	2	136	4.0e-43	166	COG1558	Flagellar basal body rod protein FlgC	137
646767621	166	32.52	2	164	1	133	1.0e-23	103	COG1815	Flagellar basal body rod protein FlgB	133
646767622	493	32.68	291	493	21	220	7.0e-29	122	COG1261	Flagella basal body P-ring formation protein FlgA	220
646767625	60	55.74	1	60	7	66	2.0e-13	67.3	COG1724	Predicted RNA binding protein YcfA, dsRBD-like fold, HicA-like mRNA interferase family	66
646767626	136	48.48	5	70	3	67	1.0e-10	58.9	COG1598	Predicted nuclease of the RNAse H fold, HicB family	73
646767627	244	38.82	1	235	16	246	6.0e-49	187	COG1191	DNA-directed RNA polymerase specialized sigma subunit	247
646767628	289	27.67	20	262	1	246	4.0e-21	95.4	COG0455	MinD-like ATPase involved in chromosome partitioning or flagellar assembly	262
646767629	662	29.23	261	621	43	390	3.0e-70	260	COG1419	Flagellar biosynthesis GTPase FlhF	407
646767630	700	56.02	3	697	1	694	0.0e+00	876	COG1298	Flagellar biosynthesis pathway, component FlhA	696
646767631	411	46.26	1	361	1	361	7.0e-121	427	COG1377	Flagellar biosynthesis protein FlhB	363
646767634	236	54.46	24	236	20	217	2.0e-59	222	COG3143	Chemotaxis regulator CheZ, phosphatase of CheY~P	217
646767636	362	55.24	3	354	1	345	1.0e-110	393	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
646767637	237	44.03	13	170	1	158	8.0e-48	183	COG1871	Chemotaxis receptor (MCP) glutamine deamidase CheD	164
646767638	320	44.69	35	297	2	268	2.0e-75	276	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
646767639	619	36.21	136	516	3	408	2.0e-48	187	COG0840	Methyl-accepting chemotaxis protein	408
646767640	177	44.08	20	171	8	159	1.0e-38	152	COG0835	Chemotaxis signal transduction protein	165
646767641	779	41.55	1	762	2	705	0.0e+00	628	COG0643	Chemotaxis protein histidine kinase CheA	716
646767643	336	31.91	11	289	1	244	7.0e-47	181	COG1360	Flagellar motor protein MotB	244
646767644	286	47.89	1	284	3	265	8.0e-72	263	COG1291	Flagellar motor component MotA	266
646767647	354	23.75	6	341	2	379	1.0e-28	121	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
646767648	100	28.7	1	97	13	127	2.0e-11	60.4	COG2916	DNA-binding protein H-NS	128
646767649	246	43.33	1	232	2	238	2.0e-44	172	COG0580	Glycerol uptake facilitator and related aquaporins (Major Intrinsic Protein Family)	241
646767652	273	29.37	1	268	2	264	8.0e-47	180	COG0561	Hydroxymethylpyrimidine pyrophosphatase and other HAD family phosphatases	264
646767653	296	34.49	5	284	5	289	2.0e-36	146	COG2971	BadF-type ATPase, related to human N-acetylglucosamine kinase	301
646767654	198	56.28	3	183	2	184	1.0e-70	259	COG2818	3-methyladenine DNA glycosylase Tag	188
646767657	313	42.24	1	313	1	309	1.0e-76	280	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
646767658	1634	32.39	861	1347	91	617	3.0e-76	281	COG3914	Predicted O-linked N-acetylglucosamine transferase, SPINDLY family	620
646767660	378	21.97	1	342	1	329	1.0e-26	114	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
646767663	251	34.25	5	249	1	251	6.0e-36	144	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
646767664	345	33.83	7	332	2	320	1.0e-61	230	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
646767666	372	39.14	7	372	1	370	6.0e-89	321	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
646767669	371	20.27	5	371	4	361	2.0e-29	123	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
646767670	405	32.84	4	405	3	360	2.0e-31	130	COG1344	Flagellin and related hook-associated protein FlgL	360
646767671	523	32.03	29	514	1	482	4.0e-33	136	COG1345	Flagellar capping protein FliD	483
646767674	305	47.83	190	303	10	124	2.0e-14	73.6	COG3245	Cytochrome c5	126
646767675	696	41.97	4	669	2	642	0.0e+00	561	COG0210	Superfamily I DNA or RNA helicase	655
646767676	349	29.06	5	344	4	339	1.0e-46	180	COG0673	Predicted dehydrogenase	342
646767678	372	47.77	1	368	2	374	7.0e-105	374	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
646767679	126	60.94	1	126	3	130	8.0e-40	155	COG0509	Glycine cleavage system H protein (lipoate-binding)	131
646767680	978	61.17	467	950	6	496	0.0e+00	724	COG1003	Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain	496
646767682	462	48.95	173	458	2	262	2.0e-88	319	COG1760	L-serine deaminase	262
646767683	575	36.62	17	568	1	548	0.0e+00	491	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
646767684	382	32.96	22	375	2	359	4.0e-58	218	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
646767685	1312	65.57	523	1312	2	769	0.0e+00	1022	COG4230	Delta 1-pyrroline-5-carboxylate dehydrogenase	769
646767688	476	24.58	112	463	9	329	6.0e-25	109	COG2855	Uncharacterized membrane protein YadS	334
646767689	745	46.33	1	745	2	730	0.0e+00	718	COG1198	Primosomal protein N' (replication factor Y) - superfamily II helicase	730
646767690	366	51.54	1	356	1	350	1.0e-118	419	COG0407	Uroporphyrinogen-III decarboxylase	352
646767691	263	29.7	8	263	1	264	8.0e-28	117	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
646767692	576	37.81	22	572	1	533	0.0e+00	473	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
646767693	141	50.37	1	134	1	135	2.0e-33	134	COG0355	FoF1-type ATP synthase, epsilon subunit	135
646767694	464	76.46	8	463	3	465	0.0e+00	818	COG0055	FoF1-type ATP synthase, beta subunit	468
646767695	294	48.97	5	294	1	286	4.0e-92	331	COG0224	FoF1-type ATP synthase, gamma subunit	287
646767696	513	69.02	1	510	1	499	0.0e+00	822	COG0056	FoF1-type ATP synthase, alpha subunit	504
646767697	179	40	1	178	1	178	4.0e-33	134	COG0712	FoF1-type ATP synthase, delta subunit	178
646767698	156	44.16	3	156	5	158	2.0e-16	78.4	COG0711	FoF1-type ATP synthase, membrane subunit b or b'	161
646767699	89	45.95	9	82	6	79	1.0e-06	44.8	COG0636	FoF1-type ATP synthase, membrane subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K	79
646767700	283	34.05	5	283	2	246	1.0e-42	166	COG0356	FoF1-type ATP synthase, membrane subunit a	246
646767701	181	28.93	63	179	4	121	8.0e-11	60.2	COG3312	FoF1-type ATP synthase assembly protein I	128
646767702	295	38.65	37	285	7	240	9.0e-34	137	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
646767703	263	40.31	1	256	1	257	1.0e-61	229	COG1192	Cellulose biosynthesis protein BcsQ	259
646767704	227	44.19	13	222	1	211	5.0e-52	197	COG0357	16S rRNA G527 N7-methylase RsmG (former glucose-inhibited division protein B)	215
646767705	652	64.25	3	636	1	621	0.0e+00	983	COG0445	tRNA U34 5-carboxymethylaminomethyl modifying enzyme MnmG/GidA	621
646767706	259	53.94	15	254	2	237	2.0e-84	305	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
646767707	594	51.59	344	592	2	250	9.0e-85	308	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
646767708	351	33.74	108	350	51	296	3.0e-29	122	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
646767709	386	30.46	17	379	1	357	3.0e-49	189	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
646767710	388	30.46	19	381	1	357	1.0e-43	171	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
646767711	324	37.46	10	321	14	314	2.0e-40	160	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
646767712	294	43.54	7	293	2	293	2.0e-49	189	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
646767713	404	25.82	24	381	1	366	1.0e-44	174	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
646767714	252	51.48	19	252	1	237	6.0e-78	283	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
646767715	259	46.99	5	249	2	250	4.0e-79	287	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
646767716	571	44.02	11	554	1	541	0.0e+00	513	COG2303	Choline dehydrogenase or related flavoprotein	542
646767717	517	40.75	25	503	2	471	6.0e-125	441	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
646767718	299	31.23	1	298	1	292	2.0e-29	123	COG0583	DNA-binding transcriptional regulator, LysR family	297
646767719	178	28.09	2	170	1	176	4.0e-21	94.6	COG1437	Adenylate cyclase class IV, CYTH domain (includes archaeal enzymes of unknown function)	178
646767720	163	44.44	1	153	3	154	6.0e-31	127	COG1522	DNA-binding transcriptional regulator, Lrp family	154
646767721	296	55.32	3	284	15	291	1.0e-97	349	COG3186	Phenylalanine-4-hydroxylase	291
646767722	96	40.43	1	94	2	95	4.0e-26	109	COG2154	Pterin-4a-carbinolamine dehydratase	101
646767724	228	40.79	1	223	1	227	3.0e-52	198	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
646767725	504	31.09	125	479	2	336	2.0e-37	150	COG0642	Signal transduction histidine kinase	336
646767727	370	42.94	1	341	3	336	2.0e-94	339	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
646767728	245	33.84	3	199	1	195	6.0e-40	157	COG0518	GMP synthase - Glutamine amidotransferase domain	198
646767729	212	29.6	21	144	3	126	2.0e-09	55.7	COG1846	DNA-binding transcriptional regulator, MarR family	126
646767730	371	40.72	11	369	2	362	2.0e-109	388	COG2170	Gamma-glutamyl:cysteine ligase YbdK, ATP-grasp superfamily	369
646767731	401	22.65	16	401	5	393	1.0e-11	64.9	COG0475	Kef-type K+ transport system, membrane component KefB	397
646767732	655	32.92	1	233	2	239	6.0e-51	195	COG4121	tRNA U34 5-methylaminomethyl-2-thiouridine-forming methyltransferase MnmC	252
646767733	92	59.34	1	91	2	92	7.0e-24	102	COG0776	Bacterial nucleoid DNA-binding protein	94
646767734	453	37.34	6	391	1	322	1.0e-75	277	COG0523	GTPase, G3E family	323
646767736	811	29.11	165	689	97	561	9.0e-67	248	COG1450	Type II secretory pathway component GspD/PulD (secretin)	587
646767737	507	53.56	24	505	9	499	0.0e+00	559	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
646767738	405	45.93	1	405	1	397	1.0e-106	380	COG1459	Type II secretory pathway, component PulF	397
646767740	154	46.94	15	153	3	149	1.0e-22	99	COG2165	Type II secretory pathway, pseudopilin PulG	149
646767741	179	20.95	27	174	2	143	5.0e-07	47.7	COG2165	Type II secretory pathway, pseudopilin PulG	149
646767744	367	29.79	16	351	2	304	9.0e-35	141	COG3156	Type II secretory pathway, component PulK	323
646767746	167	32.03	10	162	25	177	5.0e-22	97.4	COG3149	Type II secretory pathway, component PulM	181
646767748	531	38.63	26	489	1	452	2.0e-56	213	COG1538	Outer membrane protein TolC	457
646767750	169	35.48	24	146	3	126	1.0e-14	73	COG1846	DNA-binding transcriptional regulator, MarR family	126
646767753	538	46.82	13	528	5	517	0.0e+00	550	COG2918	Gamma-glutamylcysteine synthetase	518
646767754	306	34.88	18	293	1	270	1.0e-44	173	COG0122	3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase	285
646767755	410	49.16	38	215	7	184	3.0e-47	183	COG2169	Methylphosphotriester-DNA--protein-cysteine methyltransferase (N-terminal fragment of Ada), contains Zn-binding and two AraC-type DNA-binding domains	187
646767758	214	46.96	31	211	1	180	1.0e-56	212	COG4681	Uncharacterized conserved protein YaeQ, suppresses RfaH defect	181
646767759	325	31.77	14	311	1	291	7.0e-33	134	COG0583	DNA-binding transcriptional regulator, LysR family	297
646767760	482	45.03	14	480	1	467	4.0e-108	385	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
646767761	334	22.46	1	331	1	318	8.0e-24	104	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
646767762	519	50.7	22	518	1	499	0.0e+00	603	COG1129	ABC-type sugar transport system, ATPase component	500
646767763	334	41.25	33	332	12	313	1.0e-51	196	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
646767766	141	41.61	5	138	1	137	7.0e-34	136	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
646767767	311	41.72	3	310	12	324	2.0e-70	259	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
646767768	279	43.63	17	273	6	264	1.0e-68	253	COG0300	Short-chain dehydrogenase	265
646767773	464	48.17	3	464	1	454	0.0e+00	503	COG0486	tRNA U34 5-carboxymethylaminomethyl modifying GTPase MnmE/TrmE	454
646767775	552	45.7	261	552	6	305	4.0e-73	269	COG0706	Membrane protein insertase Oxa1/YidC/SpoIIIJ, required for the localization of integral membrane proteins	314
646767776	76	47.37	1	76	6	81	2.0e-23	100	COG0759	Membrane-anchored protein YidD, putatitve component of membrane protein insertase Oxa1/YidC/SpoIIIJ	92
646767777	159	39.29	27	108	1	84	1.0e-11	63	COG0594	RNase P protein component	117
646767779	174	28.05	14	170	7	152	3.0e-14	71.5	COG3772	Phage-related lysozyme (muramidase), GH24 family	152
646767781	793	19.07	36	792	10	768	9.0e-37	149	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
646767782	332	25.75	24	321	74	363	2.0e-30	126	COG4585	Signal transduction histidine kinase	365
646767783	220	47.6	6	211	1	208	6.0e-49	187	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
646767784	412	28.91	25	355	17	346	1.0e-45	177	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
646767786	252	36.16	25	246	3	225	1.0e-54	206	COG5424	Pyrroloquinoline quinone (PQQ) biosynthesis protein C	242
646767787	304	22.52	1	300	4	264	4.0e-20	92.5	COG1235	Phosphoribosyl 1,2-cyclic phosphodiesterase	269
646767788	345	26.17	19	312	2	262	3.0e-09	56.6	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
646767789	218	41.04	48	218	6	178	1.0e-33	136	COG3038	Cytochrome b561	181
646767790	278	31.98	1	222	1	220	4.0e-33	135	COG2218	Formylmethanofuran dehydrogenase subunit C	264
646767791	323	45.63	7	314	1	296	1.0e-77	283	COG2037	Formylmethanofuran:tetrahydromethanopterin formyltransferase	297
646767792	574	38.81	6	546	7	555	0.0e+00	497	COG1229	Formylmethanofuran dehydrogenase subunit A	575
646767793	459	25.06	23	424	4	402	2.0e-26	113	COG1029	Formylmethanofuran dehydrogenase subunit B	429
646767794	249	33.33	1	242	1	219	5.0e-25	108	COG1411	Uncharacterized protein related to proFAR isomerase (HisA)	229
646767795	347	28.57	3	323	2	276	1.0e-30	127	COG1821	Predicted ATP-dependent carboligase, ATP-grasp superfamily	307
646767796	369	28.65	13	353	7	330	3.0e-44	172	COG1548	Uncharacterized protein, hydantoinase/oxoprolinase family	330
646767797	196	30.97	1	154	1	152	2.0e-19	88.9	COG2054	Uncharacterized archaeal kinase related to aspartokinase	212
646767798	247	31.22	4	224	3	235	2.0e-22	99.3	COG1891	Uncharacterized protein, UPF0264 family	235
646767799	199	19.55	1	171	14	189	2.0e-07	49.5	COG2457	Uncharacterized protein	199
646767800	499	48.25	27	483	2	429	0.0e+00	544	COG1850	Ribulose 1,5-bisphosphate carboxylase, large subunit, or a RuBisCO-like protein	429
646767801	142	42.59	1	108	6	111	9.0e-32	129	COG4451	Ribulose bisphosphate carboxylase small subunit	127
646767803	367	48.82	5	342	1	325	3.0e-111	395	COG0158	Fructose-1,6-bisphosphatase	326
646767804	290	57.24	1	290	1	289	6.0e-118	417	COG3954	Phosphoribulokinase	289
646767805	682	58.3	14	677	7	661	0.0e+00	936	COG0021	Transketolase	663
646767806	345	45.76	1	329	1	286	1.0e-95	343	COG0191	Fructose/tagatose bisphosphate aldolase	286
646767807	235	56.89	1	225	1	220	1.0e-83	302	COG0036	Pentose-5-phosphate-3-epimerase	220
646767808	460	22.82	237	431	71	273	9.0e-07	48.4	COG0294	Dihydropteroate synthase	274
646767809	206	39.89	20	187	5	181	7.0e-32	130	COG1036	Archaeal flavoprotein	187
646767810	687	37.46	5	670	3	605	0.0e+00	477	COG3284	Transcriptional regulator of acetoin/glycerol metabolism	606
646767811	168	38.33	29	147	1	120	1.0e-21	96.4	COG1539	Dihydroneopterin aldolase	121
646767813	169	54.32	6	167	2	163	6.0e-48	183	COG1795	Formaldehyde-activating enzyme nesessary for methanogenesis	170
646767814	300	25.48	9	300	5	288	9.0e-22	97.7	COG1767	Triphosphoribosyl-dephospho-CoA synthetase	288
646767815	332	29.08	64	308	80	318	9.0e-29	121	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
646767816	345	39.69	21	339	2	313	3.0e-77	282	COG3252	Methenyltetrahydromethanopterin cyclohydrolase	314
646767817	406	22.56	13	398	14	384	2.0e-22	100	COG2232	Predicted ATP-dependent carboligase, ATP-grasp superfamily	389
646767819	341	32.7	14	330	2	312	8.0e-54	204	COG1907	Predicted archaeal sugar kinase	312
646767820	132	41.76	9	97	7	96	6.0e-18	83	COG2154	Pterin-4a-carbinolamine dehydratase	101
646767821	605	31.01	8	602	114	773	0.0e+00	480	COG4993	Glucose dehydrogenase	773
646767825	334	34.55	19	316	1	297	5.0e-39	155	COG0583	DNA-binding transcriptional regulator, LysR family	297
646767826	340	32.44	11	340	12	329	6.0e-39	154	COG0714	MoxR-like ATPase	329
646767833	324	39.63	3	324	8	325	4.0e-72	265	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
646767839	225	28.1	1	224	9	245	5.0e-27	114	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
646767841	245	49.79	6	244	1	239	2.0e-73	269	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
646767842	288	43.2	34	282	9	258	1.0e-50	193	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
646767843	356	30.47	23	350	2	335	4.0e-35	142	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
646767844	349	42.52	7	347	3	332	2.0e-82	299	COG4521	ABC-type taurine transport system, periplasmic component	334
646767845	259	60.87	1	253	1	253	1.0e-87	316	COG4525	ABC-type taurine transport system, ATPase component	259
646767846	294	45.06	42	294	10	257	9.0e-55	207	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
646767847	272	39.11	1	261	2	272	4.0e-40	158	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
646767848	248	33.93	4	227	9	211	1.0e-40	159	COG0765	ABC-type amino acid transport system, permease component	222
646767849	245	34.23	6	227	2	222	4.0e-41	161	COG0765	ABC-type amino acid transport system, permease component	222
646767850	338	38.18	10	337	5	328	7.0e-59	221	COG3608	Predicted deacylase	331
646767851	473	30.32	9	469	1	453	1.0e-66	247	COG2079	2-methylcitrate dehydratase PrpD	453
646767852	268	19.78	14	255	2	261	3.0e-10	59.3	COG0561	Hydroxymethylpyrimidine pyrophosphatase and other HAD family phosphatases	264
646767853	339	36.81	1	337	1	326	4.0e-61	228	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
646767854	302	32.78	4	301	2	297	5.0e-35	141	COG0583	DNA-binding transcriptional regulator, LysR family	297
646767856	240	31.06	6	239	5	236	6.0e-43	167	COG2188	DNA-binding transcriptional regulator, GntR family	236
646767857	430	22.22	32	406	31	392	7.0e-18	85.3	COG2814	Predicted arabinose efflux permease, MFS family	394
646767858	291	29.78	24	288	10	278	2.0e-43	169	COG3618	Predicted metal-dependent hydrolase, TIM-barrel fold	279
646767859	305	34.46	5	295	1	289	3.0e-27	115	COG0583	DNA-binding transcriptional regulator, LysR family	297
646767860	473	39.83	205	320	8	124	7.0e-13	69.3	COG0599	Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family	124
646767862	678	17.24	61	660	27	600	2.0e-07	51.2	COG3211	Secreted phosphatase, PhoX family	616
646767864	309	27.88	40	302	14	275	3.0e-24	106	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
646767865	333	26.46	16	326	8	330	2.0e-33	136	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
646767866	459	29.44	24	414	4	336	8.0e-43	168	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
646767867	602	60.64	354	602	3	240	2.0e-103	370	COG1126	ABC-type polar amino acid transport system, ATPase component	240
646767868	317	25.59	63	310	29	275	6.0e-23	101	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
646767869	298	45.26	15	297	2	281	2.0e-68	252	COG2175	Taurine dioxygenase, alpha-ketoglutarate-dependent	286
646767870	347	27.11	16	347	8	330	2.0e-27	116	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
646767871	276	48.02	24	275	3	248	3.0e-78	285	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
646767872	292	35.71	41	291	11	258	3.0e-39	155	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
646767876	220	34.95	28	207	15	197	7.0e-35	140	COG1573	Uracil-DNA glycosylase	202
646767877	303	30.87	8	301	4	255	4.0e-51	195	COG1801	Uncharacterized conserved protein YecE, DUF72 family	263
646767879	312	36.89	4	310	1	326	5.0e-60	224	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
646767880	166	40.78	43	143	20	122	7.0e-11	60.3	COG1846	DNA-binding transcriptional regulator, MarR family	126
646767881	366	27.78	1	348	22	367	4.0e-59	221	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
646767882	321	35.45	1	259	1	265	1.0e-50	193	COG1018	Ferredoxin-NADP reductase	266
646767885	367	32.05	58	286	19	246	4.0e-43	169	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
646767886	665	50.19	38	559	3	527	0.0e+00	527	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
646767887	213	33.33	7	204	6	205	3.0e-30	125	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
646767889	442	27.7	157	304	17	150	1.0e-06	48	COG2010	Cytochrome c, mono- and diheme variants	150
646767891	246	39.84	1	243	3	250	5.0e-46	177	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
646767892	563	33.21	21	563	9	533	4.0e-78	286	COG1283	Na+/phosphate symporter	533
646767896	451	21.46	46	446	49	447	3.0e-19	89.9	COG2271	Sugar phosphate permease	448
646767897	341	21.3	1	332	1	291	5.0e-16	78.9	COG2159	Predicted metal-dependent hydrolase, TIM-barrel fold	293
646767898	227	40.65	6	219	1	210	1.0e-42	166	COG0684	Regulator of RNase E activity RraA	210
646767899	238	24.79	2	238	20	257	6.0e-25	107	COG0725	ABC-type molybdate transport system, periplasmic component	258
646767901	323	23.1	3	296	12	324	4.0e-33	135	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
646767902	773	30.77	545	762	31	250	8.0e-32	132	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
646767903	371	24.18	2	360	27	381	1.0e-26	114	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
646767906	438	23.96	10	413	12	419	8.0e-17	82.1	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
646767907	396	21.39	1	367	1	378	1.0e-21	98.2	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
646767908	435	19.03	3	329	31	354	7.0e-08	52.1	COG3307	O-antigen ligase	424
646767909	506	41.86	28	368	2	333	1.0e-97	350	COG0836	Mannose-1-phosphate guanylyltransferase	333
646767910	460	45.26	229	460	1	226	8.0e-68	251	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
646767915	452	21.51	21	431	26	432	2.0e-19	90.6	COG2271	Sugar phosphate permease	448
646767916	328	24.12	36	316	47	326	9.0e-08	51.5	COG3608	Predicted deacylase	331
646767917	360	51.4	4	360	3	346	0.0e+00	461	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
646767921	652	39.39	70	649	3	555	0.0e+00	521	COG3829	Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding Fis domains	560
646767922	389	47.09	1	388	1	390	9.0e-122	430	COG0372	Citrate synthase	390
646767923	865	51.49	1	859	1	861	0.0e+00	1099	COG1048	Aconitase A	861
646767924	394	66.32	4	391	2	374	0.0e+00	524	COG2828	2-Methylaconitate cis-trans-isomerase PrpF (2-methyl citrate pathway)	378
646767928	104	35	1	100	2	97	1.0e-18	85	COG2329	Heme-degrading monooxygenase HmoA and related ABM domain proteins	105
646767929	335	36.99	1	335	1	326	2.0e-58	219	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
646767931	282	34.92	17	264	2	252	4.0e-45	175	COG0169	Shikimate 5-dehydrogenase	283
646767932	595	16.38	14	559	7	534	2.0e-21	97.7	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
646767933	597	15.34	8	561	4	535	7.0e-32	132	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
646767935	283	23.53	8	272	4	274	6.0e-17	81.8	COG1082	Sugar phosphate isomerase/epimerase	274
646767936	465	21.86	25	453	6	390	2.0e-17	84.5	COG2814	Predicted arabinose efflux permease, MFS family	394
646767937	284	38.46	5	250	3	243	3.0e-46	178	COG1414	DNA-binding transcriptional regulator, IclR family	246
646767939	632	34.54	69	621	28	593	7.0e-95	341	COG0465	ATP-dependent Zn proteases	596
646767941	381	28.46	1	374	11	379	5.0e-25	108	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
646767942	371	26.42	9	317	22	337	3.0e-27	116	COG4645	Uncharacterized protein	410
646767945	643	35.64	198	499	46	336	3.0e-39	157	COG0642	Signal transduction histidine kinase	336
646767946	308	37.22	1	306	1	293	4.0e-72	265	COG1131	ABC-type multidrug transport system, ATPase component	293
646767947	253	21.97	24	246	42	253	1.0e-07	50.5	COG1682	ABC-type polysaccharide/polyol phosphate export permease	263
646767951	344	25.84	38	339	19	335	2.0e-29	123	COG3240	Phospholipase/lecithinase/hemolysin	370
646767955	239	36.14	23	223	13	210	2.0e-25	109	COG1802	DNA-binding transcriptional regulator, GntR family	230
646767956	586	32.85	31	574	3	534	3.0e-110	393	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
646767957	415	36.6	1	415	4	396	7.0e-97	347	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
646767958	271	39.22	9	257	15	266	1.0e-52	200	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
646767961	315	35.35	7	300	2	294	5.0e-41	161	COG0583	DNA-binding transcriptional regulator, LysR family	297
646767962	449	19.51	17	400	12	399	2.0e-08	54.5	COG2223	Nitrate/nitrite transporter NarK	417
646767963	329	32	4	300	2	296	1.0e-29	123	COG0583	DNA-binding transcriptional regulator, LysR family	297
646767964	483	51.69	10	479	1	467	0.0e+00	517	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
646767965	325	32.19	1	318	1	300	8.0e-57	214	COG1893	Ketopantoate reductase	307
646767966	216	37.02	1	205	1	208	5.0e-28	117	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
646767968	213	41.12	21	212	3	199	9.0e-48	183	COG1739	Putative translation regulator, IMPACT (imprinted ancient) protein family	203
646767969	208	44.71	3	208	2	208	6.0e-27	114	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
646767970	209	33.16	3	197	1	195	4.0e-33	134	COG3917	2-hydroxychromene-2-carboxylate isomerase	203
646767972	371	45.71	189	362	13	180	6.0e-39	155	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
646767973	579	37.44	18	577	4	599	1.0e-120	427	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
646767974	513	36.56	164	509	35	406	2.0e-52	200	COG0840	Methyl-accepting chemotaxis protein	408
646767975	575	34.47	10	299	3	289	1.0e-62	234	COG2513	2-Methylisocitrate lyase and related enzymes, PEP mutase family	289
646767976	387	29.49	8	163	11	161	1.0e-19	91.5	COG4032	Sulfopyruvate decarboxylase, TPP-binding subunit (coenzyme M biosynthesis)	172
646767977	355	35.85	1	352	6	359	2.0e-77	282	COG0075	Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism protein PucG	383
646767980	547	32.01	7	547	1	526	2.0e-107	383	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
646767981	195	35.08	8	195	7	193	1.0e-29	122	COG2068	CTP:molybdopterin cytidylyltransferase MocA	199
646767982	737	33.56	1	736	3	727	0.0e+00	529	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
646767983	333	42.99	1	330	1	284	2.0e-66	246	COG1319	CO or xanthine dehydrogenase, FAD-binding subunit	284
646767984	259	58.68	93	258	3	153	4.0e-56	211	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
646767985	169	54.62	36	165	1	130	7.0e-44	170	COG3260	Ni,Fe-hydrogenase III small subunit	148
646767986	520	38.32	156	520	2	367	6.0e-79	288	COG3261	Ni,Fe-hydrogenase III large subunit	382
646767987	487	28.8	4	485	2	488	1.0e-50	194	COG0651	Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit	504
646767988	219	24.53	8	218	7	218	2.0e-18	86.1	COG4237	Hydrogenase-4 membrane subunit HyfE	218
646767989	316	35.24	1	313	1	309	3.0e-41	162	COG0650	Formate hydrogenlyase subunit 4	309
646767990	668	36.59	8	453	3	439	8.0e-57	215	COG0651	Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit	504
646767991	255	24.89	12	239	2	218	5.0e-11	61.8	COG3619	Uncharacterized membrane protein YoaK, UPF0700 family	226
646767993	278	26.03	37	264	37	276	5.0e-21	95	COG0421	Spermidine synthase	282
646767994	114	58.56	5	114	4	112	1.0e-35	141	COG2824	Uncharacterized Zn-ribbon-containing protein	112
646767995	269	44.44	4	259	1	260	3.0e-82	298	COG0708	Exonuclease III	261
646767998	344	32.72	18	286	1	243	1.0e-43	170	COG1360	Flagellar motor protein MotB	244
646767999	277	28.09	11	272	1	255	7.0e-27	114	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
646768000	254	35.86	3	250	2	246	4.0e-42	164	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
646768002	289	34.33	18	282	2	241	2.0e-48	186	COG0846	NAD-dependent protein deacetylase, SIR2 family	250
646768003	205	35.71	3	162	5	168	4.0e-29	121	COG3576	Predicted flavin-nucleotide-binding protein, pyridoxine 5'-phosphate oxidase superfamily	173
646768005	469	67.66	1	469	1	468	0.0e+00	786	COG0362	6-phosphogluconate dehydrogenase	473
646768008	103	19	3	101	15	110	5.0e-07	46.2	COG0662	Mannose-6-phosphate isomerase, cupin superfamily	127
646768010	342	45.03	8	340	1	342	2.0e-92	332	COG2008	Threonine aldolase	342
646768012	817	48.7	14	813	5	750	0.0e+00	864	COG0058	Glucan phosphorylase	750
646768014	400	51.51	4	399	6	402	6.0e-100	357	COG0786	Na+/glutamate symporter	404
646768015	286	27.97	8	284	13	292	2.0e-32	132	COG3315	O-Methyltransferase involved in polyketide biosynthesis	297
646768017	334	32.65	236	332	23	120	9.0e-15	74.9	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
646768018	600	34.56	31	459	3	392	1.0e-69	257	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
646768019	249	50.77	1	249	1	260	4.0e-67	247	COG2086	Electron transfer flavoprotein, alpha and beta subunits	260
646768020	315	53.92	1	315	1	311	5.0e-82	297	COG2025	Electron transfer flavoprotein, alpha subunit	313
646768021	156	35.17	1	137	9	153	3.0e-22	98.2	COG2030	Acyl dehydratase	159
646768022	580	50.79	132	576	7	444	0.0e+00	517	COG3243	Poly(3-hydroxyalkanoate) synthetase	445
646768023	333	26.05	216	331	4	122	3.0e-10	59.9	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
646768024	351	25.65	14	316	3	292	8.0e-29	121	COG3246	Uncharacterized conserved protein, DUF849 family	298
646768025	440	19.69	44	424	31	389	6.0e-18	85.6	COG2814	Predicted arabinose efflux permease, MFS family	394
646768026	326	44.51	2	326	1	326	9.0e-75	273	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
646768027	282	36.33	2	282	6	282	6.0e-47	181	COG2175	Taurine dioxygenase, alpha-ketoglutarate-dependent	286
646768028	188	40	7	186	3	176	2.0e-36	145	COG3545	Predicted esterase of the alpha/beta hydrolase fold	181
646768029	118	38.1	1	102	2	106	8.0e-17	79.2	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
646768030	541	32.48	1	535	2	525	8.0e-112	397	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
646768031	381	22.88	1	381	1	354	2.0e-23	103	COG3203	Outer membrane protein (porin)	354
646768033	147	38.52	7	130	2	133	3.0e-29	120	COG2764	Uncharacterized conserved protein PhnB, glyoxalase superfamily	136
646768034	263	38.89	12	255	1	247	4.0e-66	244	COG4312	Predicted dithiol-disulfide oxidoreductase, DUF899 family	247
646768036	141	48.72	3	119	14	130	1.0e-29	122	COG5649	Uncharacterized protein	132
646768037	583	43.72	5	571	2	574	0.0e+00	634	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
646768038	350	20.65	46	350	52	386	1.0e-17	84.3	COG1680	CubicO group peptidase, beta-lactamase class C family	390
646768039	430	20.46	79	424	63	386	2.0e-07	51	COG2814	Predicted arabinose efflux permease, MFS family	394
646768040	393	25.19	1	393	1	354	1.0e-40	160	COG3203	Outer membrane protein (porin)	354
646768041	371	26.33	10	364	29	330	1.0e-33	137	COG3608	Predicted deacylase	331
646768042	260	35.5	4	260	12	270	2.0e-42	166	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
646768043	409	25.55	63	403	5	362	2.0e-45	176	COG0687	Spermidine/putrescine-binding periplasmic protein	363
646768044	607	47.73	391	565	1	175	4.0e-41	163	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
646768045	377	51.72	1	376	1	376	4.0e-121	428	COG3454	Alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase PhnM	377
646768046	258	63.6	27	254	3	227	8.0e-82	296	COG4778	Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL	235
646768047	256	69.69	3	256	5	258	5.0e-108	383	COG4107	ABC-type phosphonate transport system, ATPase component	258
646768048	310	70.69	10	299	2	291	0.0e+00	480	COG3627	Alpha-D-ribose 1-methylphosphonate 5-phosphate C-P lyase	291
646768049	378	65.51	1	374	1	365	0.0e+00	513	COG3626	Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnI	367
646768050	203	49.23	10	202	5	196	2.0e-44	172	COG3625	Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnH	196
646768051	168	55.48	14	168	2	150	5.0e-39	153	COG3624	Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnG	151
646768052	252	35.86	14	250	1	236	2.0e-42	165	COG2188	DNA-binding transcriptional regulator, GntR family	236
646768054	183	52.46	3	183	5	186	3.0e-47	181	COG3709	Ribose 1,5-bisphosphokinase PhnN	192
646768055	302	28.09	1	297	1	294	6.0e-29	121	COG0583	DNA-binding transcriptional regulator, LysR family	297
646768056	396	53.16	20	395	14	390	3.0e-121	428	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
646768057	274	36.73	28	270	1	244	6.0e-55	207	COG1414	DNA-binding transcriptional regulator, IclR family	246
646768058	234	41.18	1	234	2	237	6.0e-41	160	COG2186	DNA-binding transcriptional regulator, FadR family	241
646768059	296	42.96	5	287	3	285	1.0e-67	250	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
646768060	442	45.12	9	437	2	412	1.0e-90	327	COG3395	Uncharacterized conserved protein YgbK, DUF1537 family	413
646768061	220	35.19	8	217	1	211	2.0e-36	145	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
646768062	266	54.92	1	264	1	260	1.0e-105	376	COG3622	Hydroxypyruvate isomerase	260
646768063	326	25.69	1	321	1	308	3.0e-37	148	COG0451	Nucleoside-diphosphate-sugar epimerase	314
646768064	400	40.05	1	400	1	392	4.0e-88	318	COG0183	Acetyl-CoA acetyltransferase	392
646768065	308	35.48	8	305	1	290	9.0e-49	187	COG1230	Co/Zn/Cd efflux system component	296
646768066	91	45.56	1	90	1	89	1.0e-15	74.5	COG1937	DNA-binding transcriptional regulator, FrmR family	89
646768069	402	26.92	67	402	1	332	1.0e-31	131	COG0642	Signal transduction histidine kinase	336
646768071	300	30.2	1	295	1	289	1.0e-34	140	COG0583	DNA-binding transcriptional regulator, LysR family	297
646768072	291	32.26	14	289	10	310	1.0e-52	199	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
646768073	302	28.14	12	302	1	291	5.0e-26	112	COG0583	DNA-binding transcriptional regulator, LysR family	297
646768074	274	37.44	1	219	1	187	1.0e-44	173	COG2249	Putative NADPH-quinone reductase (modulator of drug activity B)	189
646768075	284	25.27	39	274	37	316	8.0e-29	120	COG0627	S-formylglutathione hydrolase FrmB	316
646768076	430	39.21	81	403	1	316	1.0e-82	300	COG0540	Aspartate carbamoyltransferase, catalytic chain	316
646768077	302	38.67	1	295	2	288	1.0e-58	220	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
646768079	151	37.61	32	138	2	108	3.0e-13	68	COG0607	Rhodanese-related sulfurtransferase	110
646768080	319	37.9	6	317	15	324	8.0e-70	257	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
646768082	405	25.49	1	397	1	407	9.0e-58	218	COG4320	Uncharacterized conserved protein, DUF2252 family	410
646768083	492	34.69	30	490	6	460	1.0e-53	204	COG0471	Di- and tricarboxylate transporter	461
646768084	315	41.85	5	314	2	310	1.0e-66	247	COG0039	Malate/lactate dehydrogenase	313
646768093	472	42.05	37	458	7	444	6.0e-124	438	COG2723	Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase	460
646768094	412	23.13	1	411	5	427	4.0e-29	122	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
646768095	318	31.51	24	314	2	293	3.0e-53	202	COG1175	ABC-type sugar transport system, permease component	295
646768096	305	32.98	21	304	3	281	5.0e-53	201	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
646768097	386	47.58	31	381	2	338	3.0e-116	412	COG3839	ABC-type sugar transport system, ATPase component	338
646768098	350	34.23	6	339	1	333	1.0e-70	260	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
646768099	563	26.31	21	554	23	551	1.0e-85	311	COG0659	Sulfate permease or related transporter, MFS superfamily	554
646768101	532	38	202	526	59	408	1.0e-55	210	COG0840	Methyl-accepting chemotaxis protein	408
646768103	388	26.64	28	291	18	279	6.0e-22	98.9	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
646768105	501	46.85	31	501	5	443	0.0e+00	525	COG0174	Glutamine synthetase	443
646768106	486	35.82	7	486	2	457	3.0e-54	206	COG0471	Di- and tricarboxylate transporter	461
646768108	549	41.08	85	486	8	396	1.0e-82	301	COG0029	Aspartate oxidase	518
646768109	414	44.78	18	410	24	418	3.0e-114	405	COG1894	NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F)	424
646768110	602	20.33	114	602	55	458	6.0e-22	99.6	COG0471	Di- and tricarboxylate transporter	461
646768111	553	40.11	11	553	9	539	0.0e+00	540	COG0405	Gamma-glutamyltranspeptidase	539
646768113	544	24.34	14	541	7	516	3.0e-55	210	COG1620	L-lactate permease	522
646768115	212	32.51	12	212	7	208	3.0e-19	88.4	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
646768116	291	34.81	1	289	2	291	3.0e-31	128	COG0583	DNA-binding transcriptional regulator, LysR family	297
646768117	144	58.99	6	144	1	138	3.0e-46	177	COG3565	Predicted dioxygenase of extradiol dioxygenase family	138
646768118	1091	29.04	2	1036	1	1004	0.0e+00	666	COG0841	Multidrug efflux pump subunit AcrB	1009
646768119	408	27.61	35	402	2	372	5.0e-24	105	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
646768120	521	35.76	24	488	1	454	1.0e-57	217	COG1538	Outer membrane protein TolC	457
646768121	228	45.65	1	223	1	229	2.0e-54	205	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
646768122	500	31.97	150	464	31	335	3.0e-35	143	COG0642	Signal transduction histidine kinase	336
646768123	388	38.99	6	373	1	353	6.0e-70	258	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
646768124	530	36.99	5	521	9	520	1.0e-113	403	COG4943	Environmental sensor c-di-GMP phosphodiesterase, contains periplasmic CSS-motif sensor and cytoplasmic EAL domain	524
646768125	193	42.27	1	193	1	191	7.0e-42	163	COG2353	Polyisoprenoid-binding periplasmic protein YceI	192
646768126	191	28.12	5	188	1	191	3.0e-26	111	COG2353	Polyisoprenoid-binding periplasmic protein YceI	192
646768127	187	42.29	8	182	5	179	6.0e-36	143	COG3038	Cytochrome b561	181
646768128	416	28.29	10	409	9	418	2.0e-52	200	COG1055	Na+/H+ antiporter NhaD or related arsenite permease	424
646768132	237	43.48	6	234	2	228	7.0e-52	197	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
646768133	456	29.43	153	456	21	332	3.0e-32	133	COG0642	Signal transduction histidine kinase	336
646768136	886	25	287	564	66	329	1.0e-31	132	COG0642	Signal transduction histidine kinase	336
646768137	1550	24.23	349	572	20	238	1.0e-08	56.5	COG3063	Tfp pilus assembly protein PilF	250
646768138	395	37.64	34	380	16	350	5.0e-55	208	COG3405	Endo-1,4-beta-D-glucanase Y	360
646768140	735	25.18	113	526	12	401	2.0e-48	187	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
646768141	262	30.89	1	254	2	257	1.0e-29	123	COG1192	Cellulose biosynthesis protein BcsQ	259
646768146	267	66.93	1	254	1	254	8.0e-88	316	COG3836	2-keto-3-deoxy-L-rhamnonate aldolase RhmA	255
646768147	267	54.31	1	267	1	262	3.0e-88	318	COG3971	2-keto-4-pentenoate hydratase	264
646768148	132	46.56	1	131	1	126	1.0e-35	141	COG3232	5-carboxymethyl-2-hydroxymuconate isomerase	127
646768149	287	34.05	5	282	1	268	6.0e-69	254	COG3384	Aromatic ring-opening dioxygenase, catalytic subunit, LigB family	268
646768150	485	48.23	3	478	1	472	0.0e+00	511	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
646768151	252	45.83	33	244	48	263	1.0e-63	236	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
646768152	257	25.65	12	236	29	252	5.0e-28	118	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
646768153	149	25.44	29	142	12	125	2.0e-08	52.2	COG1846	DNA-binding transcriptional regulator, MarR family	126
646768154	382	37.01	1	380	11	368	2.0e-79	289	COG3616	D-serine deaminase, pyridoxal phosphate-dependent	368
646768155	224	30.53	13	216	3	227	2.0e-17	82.6	COG1011	FMN phosphatase YigB, HAD superfamily	229
646768156	301	24.08	3	299	2	297	3.0e-29	122	COG0583	DNA-binding transcriptional regulator, LysR family	297
646768158	145	47.22	2	145	1	143	5.0e-46	176	COG0757	3-dehydroquinate dehydratase	146
646768159	356	31.55	1	345	1	338	1.0e-44	173	COG0673	Predicted dehydrogenase	342
646768160	467	20.82	61	414	53	382	9.0e-06	45.2	COG2814	Predicted arabinose efflux permease, MFS family	394
646768161	318	30.98	15	304	3	292	2.0e-33	137	COG0583	DNA-binding transcriptional regulator, LysR family	297
646768162	449	20.11	49	400	49	391	3.0e-08	53.7	COG2814	Predicted arabinose efflux permease, MFS family	394
646768163	188	28.22	8	186	4	205	2.0e-21	95.7	COG1335	Nicotinamidase-related amidase	205
646768164	150	30.3	39	137	19	116	1.0e-08	52.2	COG1846	DNA-binding transcriptional regulator, MarR family	126
646768165	215	33.5	13	215	1	206	3.0e-22	98.4	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
646768167	352	43.55	1	352	3	361	1.0e-88	320	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
646768168	100	33.68	1	95	11	93	6.0e-12	62.5	COG0640	DNA-binding transcriptional regulator, ArsR family	110
646768170	262	34.15	11	249	1	246	3.0e-40	158	COG1414	DNA-binding transcriptional regulator, IclR family	246
646768171	424	21.88	18	287	20	302	1.0e-23	104	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
646768172	260	38.91	6	258	2	251	8.0e-40	157	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
646768173	319	32.21	3	257	1	265	1.0e-52	200	COG1018	Ferredoxin-NADP reductase	266
646768174	419	20.88	32	367	26	388	2.0e-24	106	COG2271	Sugar phosphate permease	448
646768175	368	24.24	16	368	5	354	7.0e-41	161	COG3203	Outer membrane protein (porin)	354
646768177	410	22.85	93	384	67	351	8.0e-07	48.5	COG5322	Predicted amino acid dehydrogenase	351
646768178	465	28.97	224	463	80	311	1.0e-26	114	COG2829	Outer membrane phospholipase A	317
646768179	667	33.85	7	195	4	198	7.0e-29	122	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
646768181	158	26.17	1	147	1	136	1.0e-19	89.6	COG1764	Organic hydroperoxide reductase OsmC/OhrA	143
646768183	156	40.65	1	155	1	154	3.0e-33	134	COG1522	DNA-binding transcriptional regulator, Lrp family	154
646768184	226	36.94	2	223	1	203	2.0e-28	119	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
646768185	57	39.29	2	57	5	59	5.0e-07	46.1	COG3313	Predicted Fe-S protein YdhL, DUF1289 family	74
646768186	108	62.04	1	107	2	109	2.0e-25	107	COG1742	Uncharacterized inner membrane protein YnfA, drug/metabolite transporter superfamily	109
646768187	170	62.87	1	167	26	192	1.0e-62	232	COG3812	Uncharacterized protein	193
646768189	554	29.24	53	538	41	496	8.0e-84	304	COG2939	Carboxypeptidase C (cathepsin A)	498
646768193	286	39.77	24	280	4	260	6.0e-65	240	COG0171	NH3-dependent NAD+ synthetase	268
646768196	518	28.63	3	518	21	514	5.0e-62	232	COG0661	Predicted unusual protein kinase regulating ubiquinone biosynthesis, AarF/ABC1/UbiB family	517
646768197	251	41.67	1	251	1	252	4.0e-62	231	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
646768198	363	29.04	55	349	1	296	1.0e-30	127	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
646768199	371	43.85	30	371	1	352	1.0e-92	333	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
646768200	320	32.1	50	317	15	274	1.0e-29	123	COG0555	ABC-type sulfate transport system, permease component	274
646768201	287	35.25	27	285	6	262	3.0e-30	125	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
646768202	251	42.86	5	235	1	230	2.0e-32	132	COG1802	DNA-binding transcriptional regulator, GntR family	230
646768203	421	20.61	12	385	30	411	1.0e-25	111	COG1524	Predicted pyrophosphatase or phosphodiesterase, AlkP superfamily	450
646768204	483	41.95	18	482	5	469	7.0e-115	407	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
646768205	186	51.65	1	181	5	186	8.0e-50	189	COG4341	Predicted HD phosphohydrolase	186
646768211	336	30.13	3	300	2	297	6.0e-37	148	COG0583	DNA-binding transcriptional regulator, LysR family	297
646768212	737	26.43	36	733	3	668	5.0e-60	226	COG1289	Uncharacterized membrane protein YccC	674
646768214	505	53.56	7	504	1	501	0.0e+00	569	COG0427	Acyl-CoA hydrolase	501
646768216	387	34.42	124	383	13	283	5.0e-36	145	COG1408	Predicted phosphohydrolase, MPP superfamily	284
646768218	194	23.12	7	190	4	201	7.0e-21	93.9	COG0778	Nitroreductase	207
646768219	200	28.65	1	188	6	194	5.0e-24	104	COG3145	Alkylated DNA repair dioxygenase AlkB	194
646768220	328	30.65	10	314	6	307	9.0e-37	147	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
646768221	546	48.26	29	544	2	500	0.0e+00	575	COG1129	ABC-type sugar transport system, ATPase component	500
646768222	347	40.24	4	331	1	313	2.0e-38	153	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
646768223	365	37.1	18	326	10	314	1.0e-50	194	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
646768224	315	30.66	4	277	9	270	2.0e-66	246	COG2326	Polyphosphate kinase 2, PPK2 family	270
646768225	918	39.65	6	893	19	913	0.0e+00	750	COG0474	Magnesium-transporting ATPase (P-type)	917
646768227	310	36.93	1	280	3	287	2.0e-49	190	COG0331	Malonyl CoA-acyl carrier protein transacylase	310
646768230	294	30.56	16	254	55	288	2.0e-37	149	COG0777	Acetyl-CoA carboxylase beta subunit	294
646768232	327	33.57	39	319	5	283	7.0e-36	144	COG1767	Triphosphoribosyl-dephospho-CoA synthetase	288
646768234	256	35.22	12	238	1	230	7.0e-32	130	COG1802	DNA-binding transcriptional regulator, GntR family	230
646768235	432	20.22	66	431	47	394	6.0e-11	62.5	COG2814	Predicted arabinose efflux permease, MFS family	394
646768236	310	22.03	61	291	63	282	5.0e-09	55.3	COG5006	Threonine/homoserine efflux transporter RhtA	292
646768237	285	38.65	5	242	1	248	5.0e-29	122	COG0583	DNA-binding transcriptional regulator, LysR family	297
646768239	507	25.47	89	507	39	439	4.0e-35	143	COG3659	Carbohydrate-selective porin OprB	439
646768241	278	47.33	4	265	3	263	8.0e-71	260	COG2162	Arylamine N-acetyltransferase	275
646768242	226	29.26	41	226	8	187	1.0e-14	73.5	COG2020	Protein-S-isoprenylcysteine O-methyltransferase Ste14	187
646768243	259	33.91	28	255	1	232	5.0e-46	178	COG2188	DNA-binding transcriptional regulator, GntR family	236
646768244	270	36.91	31	261	4	236	6.0e-52	197	COG2188	DNA-binding transcriptional regulator, GntR family	236
646768245	295	60.08	29	276	1	237	1.0e-105	376	COG1126	ABC-type polar amino acid transport system, ATPase component	240
646768246	220	42.03	12	217	14	220	4.0e-43	167	COG0765	ABC-type amino acid transport system, permease component	222
646768247	216	46.38	11	216	15	221	1.0e-48	186	COG0765	ABC-type amino acid transport system, permease component	222
646768248	275	31.37	7	269	5	272	1.0e-30	127	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
646768249	324	41.25	1	316	1	314	3.0e-70	259	COG3491	Isopenicillin N synthase and related dioxygenases	322
646768250	479	36.36	27	479	1	457	8.0e-80	291	COG0277	FAD/FMN-containing dehydrogenase	459
646768251	1138	21.9	8	564	1	538	8.0e-37	149	COG2303	Choline dehydrogenase or related flavoprotein	542
646768253	631	30.49	112	434	6	325	2.0e-37	151	COG0642	Signal transduction histidine kinase	336
646768254	247	31.84	1	243	1	211	3.0e-38	152	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
646768256	334	44.02	1	333	5	346	1.0e-70	260	COG1294	Cytochrome bd-type quinol oxidase, subunit 2	346
646768257	478	47.38	5	437	2	440	0.0e+00	477	COG1271	Cytochrome bd-type quinol oxidase, subunit 1	457
646768258	273	29.27	1	273	1	281	3.0e-31	129	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
646768259	265	28.63	2	225	1	227	5.0e-23	101	COG0451	Nucleoside-diphosphate-sugar epimerase	314
646768262	297	50.35	2	285	1	286	2.0e-80	292	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
646768263	266	53.57	10	260	4	255	2.0e-82	299	COG3836	2-keto-3-deoxy-L-rhamnonate aldolase RhmA	255
646768264	527	26.04	6	503	2	472	1.0e-54	208	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
646768265	247	37.3	8	246	2	241	2.0e-42	165	COG2186	DNA-binding transcriptional regulator, FadR family	241
646768266	452	22.72	22	441	27	435	1.0e-28	121	COG2271	Sugar phosphate permease	448
646768267	305	33.67	13	303	6	295	1.0e-51	197	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
646768268	529	40.8	106	529	1	381	6.0e-114	405	COG2721	Altronate dehydratase	381
646768269	283	24.31	17	281	2	288	2.0e-24	106	COG0451	Nucleoside-diphosphate-sugar epimerase	314
646768270	309	37.54	21	305	27	307	1.0e-62	233	COG3386	Sugar lactone lactonase YvrE	307
646768271	330	35.35	3	330	2	330	8.0e-79	287	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
646768272	169	31.9	1	163	2	164	6.0e-19	87.3	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
646768273	450	40.5	46	445	1	379	9.0e-84	304	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
646768274	403	22.17	1	403	1	354	1.0e-39	157	COG3203	Outer membrane protein (porin)	354
646768275	61	42.62	1	60	1	61	7.0e-11	58.8	COG1942	Phenylpyruvate tautomerase PptA, 4-oxalocrotonate tautomerase family	69
646768279	290	31.06	9	280	2	294	5.0e-23	101	COG4413	Urea transporter	319
646768280	184	41.11	5	180	11	190	8.0e-40	156	COG3554	Uncharacterized protein	190
646768281	193	45.83	12	178	3	169	5.0e-46	177	COG1247	L-amino acid N-acyltransferase YncA	169
646768282	302	20.88	1	293	1	275	4.0e-23	102	COG1737	DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains	281
646768284	479	36.13	11	467	2	452	7.0e-97	348	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
646768285	357	30.38	11	300	11	292	3.0e-32	132	COG2358	TRAP-type uncharacterized transport system, periplasmic component	321
646768288	270	26.26	61	239	1	179	2.0e-10	60	COG1309	DNA-binding transcriptional regulator, AcrR family	201
646768289	243	38.5	26	225	21	204	1.0e-37	150	COG0684	Regulator of RNase E activity RraA	210
646768291	193	35.21	38	179	1	141	3.0e-28	118	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
646768292	208	33.5	2	204	1	203	2.0e-31	128	COG0625	Glutathione S-transferase	211
646768294	315	22.52	4	144	3	152	8.0e-06	45	COG2236	Hypoxanthine phosphoribosyltransferase	192
646768295	188	34.29	49	187	15	154	9.0e-23	100	COG3915	Uncharacterized protein	155
646768296	615	35.92	191	469	56	333	2.0e-38	154	COG0642	Signal transduction histidine kinase	336
646768298	446	36.46	39	427	1	389	4.0e-58	219	COG3550	Serine/threonine protein kinase HipA, toxin component of the HipAB toxin-antitoxin module	392
646768300	446	30.37	19	437	2	384	5.0e-49	188	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
646768303	310	26.1	5	309	3	320	2.0e-34	140	COG2423	Ornithine cyclodeaminase/archaeal alanine dehydrogenase, mu-crystallin family	330
646768304	493	51.43	7	491	1	483	0.0e+00	633	COG0364	Glucose-6-phosphate 1-dehydrogenase	483
646768305	381	34.31	36	373	4	309	6.0e-53	201	COG1957	Inosine-uridine nucleoside N-ribohydrolase	311
646768306	318	30.77	4	297	2	293	3.0e-35	142	COG0583	DNA-binding transcriptional regulator, LysR family	297
646768307	350	44.13	1	347	1	339	2.0e-118	419	COG1064	D-arabinose 1-dehydrogenase, Zn-dependent alcohol dehydrogenase family	339
646768308	322	35.43	179	305	1	127	7.0e-20	91.5	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
646768309	268	30.99	36	265	1	241	3.0e-46	178	COG2041	Periplasmic DMSO/TMAO reductase YedYZ, molybdopterin-dependent catalytic subunit	271
646768310	216	43.22	9	202	21	219	9.0e-43	166	COG4117	Thiosulfate reductase cytochrome b subunit	221
646768312	223	47.39	1	223	1	229	1.0e-54	205	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
646768313	466	31.35	152	466	21	330	3.0e-35	143	COG0642	Signal transduction histidine kinase	336
646768315	492	34.5	315	479	3	173	3.0e-25	109	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
646768316	269	30.43	34	262	10	236	8.0e-34	137	COG2188	DNA-binding transcriptional regulator, GntR family	236
646768318	332	40.83	1	332	3	340	6.0e-78	284	COG2055	Malate/lactate/ureidoglycolate dehydrogenase, LDH2 family	349
646768321	861	27.27	33	623	105	651	5.0e-96	346	COG0209	Ribonucleotide reductase alpha subunit	696
646768323	364	23.36	16	364	4	342	1.0e-26	114	COG0628	Predicted PurR-regulated permease PerM	355
646768324	290	22.33	12	272	12	307	9.0e-21	94.4	COG0627	S-formylglutathione hydrolase FrmB	316
646768325	370	27.62	5	357	20	376	3.0e-31	129	COG4645	Uncharacterized protein	410
646768326	392	23.71	12	392	6	354	8.0e-55	207	COG3203	Outer membrane protein (porin)	354
646768327	315	28.46	83	315	3	269	6.0e-24	104	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
646768329	151	51.33	1	149	3	152	2.0e-55	208	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
646768330	750	27.99	79	747	35	724	7.0e-86	312	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
646768331	434	24.48	155	296	17	150	3.0e-06	46.9	COG2010	Cytochrome c, mono- and diheme variants	150
646768332	234	25.11	1	209	2	231	6.0e-24	104	COG0300	Short-chain dehydrogenase	265
646768333	148	35.29	29	145	27	142	1.0e-19	89.2	COG1764	Organic hydroperoxide reductase OsmC/OhrA	143
646768334	148	30.83	29	145	27	142	1.0e-18	85.4	COG1764	Organic hydroperoxide reductase OsmC/OhrA	143
646768337	196	50	6	106	5	106	9.0e-25	106	COG1733	DNA-binding transcriptional regulator, HxlR family	120
646768338	218	41.59	4	216	9	222	6.0e-53	200	COG0765	ABC-type amino acid transport system, permease component	222
646768339	257	44.59	3	220	1	222	2.0e-51	195	COG0765	ABC-type amino acid transport system, permease component	222
646768340	271	29.85	15	270	3	270	8.0e-31	127	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
646768341	364	43.92	1	361	3	352	1.0e-104	373	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
646768342	297	35.58	26	292	4	261	9.0e-44	170	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
646768343	327	40.21	39	323	6	286	8.0e-47	181	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
646768344	364	24.73	1	363	2	357	9.0e-35	141	COG0687	Spermidine/putrescine-binding periplasmic protein	363
646768345	297	25.83	5	297	1	293	1.0e-32	133	COG0583	DNA-binding transcriptional regulator, LysR family	297
646768346	360	37.22	10	360	11	367	3.0e-54	206	COG0387	Ca2+/H+ antiporter	368
646768348	223	41.75	24	215	5	197	1.0e-43	169	COG2094	3-methyladenine DNA glycosylase Mpg	200
646768351	224	56.99	28	220	3	193	2.0e-62	232	COG0807	GTP cyclohydrolase II	193
646768353	302	25.1	1	247	2	241	4.0e-11	62.2	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
646768354	303	36.36	185	294	18	127	3.0e-18	86.1	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
646768355	283	33.09	1	277	1	256	2.0e-28	119	COG5662	Transmembrane transcriptional regulator (anti-sigma factor RsiW)	256
646768356	172	37.2	1	162	15	178	3.0e-25	108	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
646768360	179	33.15	1	179	1	181	3.0e-25	108	COG3038	Cytochrome b561	181
646768361	1172	33.67	455	1163	78	864	5.0e-94	340	COG0553	Superfamily II DNA or RNA helicase, SNF2 family	866
646768362	246	38.33	1	225	1	226	1.0e-48	187	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
646768363	475	22	52	401	7	318	4.0e-29	122	COG4254	Uncharacterized conserved protein, contains LysM and FecR  domains	339
646768364	828	29.95	15	392	2	397	1.0e-47	185	COG4252	Extracellular (periplasmic) sensor domain CHASE2 (specificity unknown)	400
646768366	219	30.99	9	211	1	207	3.0e-23	101	COG0778	Nitroreductase	207
646768367	441	40.72	14	436	1	447	6.0e-123	434	COG1797	Cobyrinic acid a,c-diamide synthase	451
646768368	200	52.76	3	200	1	198	5.0e-68	250	COG2109	ATP:corrinoid adenosyltransferase	198
646768369	411	51.9	4	240	2	237	3.0e-69	255	COG0007	Uroporphyrinogen-III methylase (siroheme synthase)	244
646768370	372	39.5	17	365	1	322	2.0e-77	282	COG0523	GTPase, G3E family	323
646768371	1272	37.43	4	1269	1	1250	0.0e+00	1096	COG1429	Cobalamin biosynthesis protein CobN, Mg-chelatase	1388
646768372	363	42.16	23	353	11	379	3.0e-80	292	COG1239	Mg-chelatase subunit ChlI	423
646768373	204	30.77	10	202	40	247	3.0e-22	98.8	COG1240	Mg-chelatase subunit ChlD	261
646768374	314	23.16	120	303	35	223	3.0e-07	49.5	COG5581	c-di-GMP-binding flagellar brake protein YcgR, contains PilZNR and PilZ domains	233
646768380	398	34.6	26	390	7	354	1.0e-55	210	COG5621	Predicted secreted hydrolase	354
646768381	859	23.17	19	397	4	406	2.0e-21	98.4	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
646768382	244	47.56	12	228	2	226	9.0e-68	250	COG1136	ABC-type lipoprotein export system, ATPase component	226
646768383	518	46.65	3	491	3	493	0.0e+00	469	COG1008	NADH:ubiquinone oxidoreductase subunit 4 (chain M)	497
646768384	297	49	15	265	6	247	2.0e-68	252	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
646768385	673	53.83	38	608	1	566	0.0e+00	616	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
646768386	201	42.49	10	201	20	209	3.0e-40	158	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
646768387	113	55.56	4	111	2	109	5.0e-22	96.1	COG3125	Heme/copper-type cytochrome/quinol oxidase, subunit 4	111
646768389	476	50.45	3	336	2	333	2.0e-122	433	COG0836	Mannose-1-phosphate guanylyltransferase	333
646768391	228	34.38	5	227	1	221	5.0e-38	151	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
646768394	188	43.33	8	182	1	179	2.0e-24	105	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
646768396	169	42.34	10	146	8	138	3.0e-14	71.3	COG5612	Uncharacterized membrane protein	148
646768397	506	43.8	10	506	24	496	3.0e-97	349	COG5267	Uncharacterized conserved protein, DUF1800 family	496
646768398	382	38.83	2	381	7	418	2.0e-64	240	COG4102	Uncharacterized conserved protein, DUF1501 family	418
646768399	181	35.5	1	166	3	170	3.0e-32	131	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
646768400	464	23.38	25	423	4	336	2.0e-41	164	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
646768404	375	34.67	153	374	8	229	1.0e-28	121	COG1814	Predicted Fe2+/Mn2+ transporter, VIT1/CCC1 family	229
646768406	391	50.65	2	384	1	383	0.0e+00	461	COG4175	ABC-type proline/glycine betaine transport system, ATPase component	386
646768407	300	56.58	4	284	10	290	3.0e-95	341	COG4176	ABC-type proline/glycine betaine transport system, permease component	290
646768408	331	48.42	14	328	5	320	2.0e-98	353	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
646768409	360	44.44	14	336	5	321	7.0e-91	327	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
646768410	464	49.29	179	460	1	262	2.0e-86	313	COG1760	L-serine deaminase	262
646768411	414	28.75	29	404	1	387	2.0e-58	220	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
646768412	111	55.17	1	87	1	87	2.0e-33	133	COG4311	Sarcosine oxidase delta subunit	97
646768413	1000	37.82	608	999	3	379	4.0e-107	383	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
646768414	218	37.37	21	216	2	187	2.0e-41	162	COG4583	Sarcosine oxidase gamma subunit	189
646768416	393	29.98	1	387	1	380	2.0e-39	157	COG1680	CubicO group peptidase, beta-lactamase class C family	390
646768417	399	30.05	4	392	2	350	3.0e-55	209	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
646768418	331	48.45	1	320	2	323	2.0e-100	359	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
646768419	424	64.44	6	424	1	412	0.0e+00	665	COG0112	Glycine/serine hydroxymethyltransferase	413
646768420	323	39.27	4	322	6	312	3.0e-87	315	COG2355	Zn-dependent dipeptidase, microsomal dipeptidase homolog	313
646768422	687	43.82	1	368	1	363	3.0e-103	369	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
646768423	641	25.72	245	641	2	386	1.0e-62	234	COG0247	Fe-S oxidoreductase	388
646768424	396	33.13	63	374	2	313	6.0e-50	191	COG2025	Electron transfer flavoprotein, alpha subunit	313
646768425	259	23.79	1	258	15	260	9.0e-22	97.2	COG2086	Electron transfer flavoprotein, alpha and beta subunits	260
646768426	428	30.96	19	419	4	367	2.0e-68	253	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
646768427	396	35.52	46	335	7	265	1.0e-66	247	COG1018	Ferredoxin-NADP reductase	266
646768428	285	39.06	1	285	1	295	2.0e-61	229	COG2113	ABC-type proline/glycine betaine transport system, periplasmic component	302
646768429	291	53.66	5	291	3	287	5.0e-115	407	COG0788	Formyltetrahydrofolate hydrolase	287
646768430	304	32.01	8	304	2	297	4.0e-31	128	COG0583	DNA-binding transcriptional regulator, LysR family	297
646768431	213	34.43	10	213	1	211	7.0e-31	127	COG0625	Glutathione S-transferase	211
646768432	327	19.67	17	199	1	155	1.0e-11	63.9	COG3576	Predicted flavin-nucleotide-binding protein, pyridoxine 5'-phosphate oxidase superfamily	173
646768433	134	25.83	13	132	10	119	1.0e-09	55.7	COG3415	Transposase	138
646768436	488	33.86	36	473	20	442	6.0e-38	152	COG0531	Amino acid transporter	466
646768437	403	36.2	6	385	3	372	8.0e-26	111	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
646768438	1065	47.45	1	1035	2	1009	0.0e+00	936	COG0841	Multidrug efflux pump subunit AcrB	1009
646768439	497	38.83	19	479	1	448	1.0e-63	237	COG1538	Outer membrane protein TolC	457
646768440	472	43.37	41	366	16	345	5.0e-67	248	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
646768442	433	23.36	3	418	20	437	7.0e-34	138	COG2271	Sugar phosphate permease	448
646768443	242	43.82	8	240	3	251	1.0e-40	159	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
646768444	285	35.1	37	281	2	246	6.0e-49	187	COG1414	DNA-binding transcriptional regulator, IclR family	246
646768445	347	65.78	5	341	1	336	2.0e-129	455	COG1077	Actin-like ATPase involved in cell morphogenesis	342
646768447	231	43.93	16	224	5	215	1.0e-42	166	COG3132	Uncharacterized conserved protein YceH, UPF0502 family	215
646768448	131	33.87	3	125	13	134	2.0e-18	84.3	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
646768450	383	44.58	10	380	3	395	2.0e-100	359	COG0282	Acetate kinase	396
646768451	797	62.37	4	795	6	791	0.0e+00	1137	COG3957	Phosphoketolase	793
646768454	232	21.49	12	220	6	225	2.0e-10	59.1	COG1011	FMN phosphatase YigB, HAD superfamily	229
646768455	344	54.3	1	336	1	298	6.0e-112	397	COG1023	6-phosphogluconate dehydrogenase (decarboxylating)	300
646768456	447	18.23	46	417	44	390	3.0e-07	50.2	COG2814	Predicted arabinose efflux permease, MFS family	394
646768460	139	41.01	1	138	1	137	3.0e-37	147	COG0432	Thiamin phosphate synthase YjbQ, UPF0047 family	137
646768461	339	49.09	6	334	4	332	2.0e-102	365	COG3588	Fructose-bisphosphate aldolase class 1	332
646768463	714	24.21	22	579	1	601	2.0e-27	118	COG4191	Signal transduction histidine kinase regulating C4-dicarboxylate transport system	603
646768466	688	25.21	28	392	17	354	5.0e-44	173	COG0628	Predicted PurR-regulated permease PerM	355
646768468	737	51.19	9	714	10	696	0.0e+00	805	COG1523	Pullulanase/glycogen debranching enzyme	697
646768470	753	36.5	12	753	1	727	0.0e+00	494	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
646768471	335	37.24	1	328	1	282	9.0e-59	220	COG1319	CO or xanthine dehydrogenase, FAD-binding subunit	284
646768472	185	63.76	18	165	3	151	2.0e-57	215	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
646768474	288	43.6	41	284	1	249	1.0e-51	196	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
646768476	557	28.4	68	544	9	435	1.0e-53	204	COG1793	ATP-dependent DNA ligase	444
646768477	360	21	12	345	13	426	3.0e-33	136	COG1236	RNA processing exonuclease, beta-lactamase fold, Cft2 family	427
646768478	300	25.09	4	285	4	287	4.0e-17	82.3	COG1295	Uncharacterized membrane protein, BrkB/YihY/UPF0761 family (not an RNase)	303
646768479	611	35.56	4	580	3	550	2.0e-118	420	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
646768480	367	35.96	5	352	13	367	1.0e-68	253	COG1485	Predicted ATPase	367
646768484	157	50	1	156	21	173	9.0e-46	175	COG1881	Uncharacterized conserved protein, phosphatidylethanolamine-binding protein (PEBP) family	174
646768485	323	38.98	190	307	8	125	1.0e-17	84.5	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
646768486	277	35.38	1	191	3	197	5.0e-44	171	COG0300	Short-chain dehydrogenase	265
646768489	320	29.33	172	315	6	154	3.0e-11	62.7	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
646768490	157	24.09	8	141	6	139	6.0e-16	76.8	COG2193	Bacterioferritin (cytochrome b1)	157
646768491	693	52.65	7	685	5	663	0.0e+00	894	COG0021	Transketolase	663
646768492	181	43.71	15	177	2	163	4.0e-39	153	COG4297	Uncharacterized protein YjlB	163
646768498	224	31.92	4	216	2	203	2.0e-25	109	COG2095	Small neutral amino acid transporter SnatA, MarC family	203
646768500	491	28.31	1	486	3	492	2.0e-50	193	COG0591	Na+/proline symporter	493
646768501	216	35.75	5	207	3	206	3.0e-22	98.7	COG0625	Glutathione S-transferase	211
646768502	398	41.85	208	389	1	181	8.0e-34	138	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
646768505	133	29.52	39	132	22	126	5.0e-12	63.5	COG3794	Plastocyanin	128
646768507	319	25.74	47	311	2	258	4.0e-35	142	COG0656	Aldo/keto reductase, related to diketogulonate reductase	280
646768508	204	24.74	5	185	4	195	4.0e-12	64.9	COG1011	FMN phosphatase YigB, HAD superfamily	229
646768509	391	20.06	79	384	4	280	4.0e-09	56.2	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
646768510	259	38	9	255	1	248	1.0e-65	242	COG0496	Broad specificity polyphosphatase and 5'/3'-nucleotidase SurE	252
646768512	211	42.23	1	202	4	205	8.0e-50	190	COG0288	Carbonic anhydrase	207
646768514	242	56.02	1	239	3	243	2.0e-90	325	COG2875	Precorrin-4 methylase	254
646768515	246	43.03	1	236	2	251	4.0e-56	211	COG2099	Precorrin-6x reductase	257
646768516	366	43.8	9	366	7	362	3.0e-99	355	COG1903	Cobalamin biosynthesis protein CbiD	367
646768517	459	44.32	271	452	3	187	2.0e-58	220	COG2242	Precorrin-6B methylase 2	187
646768518	489	26.54	24	484	27	481	5.0e-66	245	COG0155	Sulfite reductase, beta subunit (hemoprotein)	510
646768519	208	52.63	1	208	1	207	9.0e-61	226	COG2082	Precorrin isomerase	210
646768520	247	50.21	8	247	1	234	2.0e-72	265	COG2243	Precorrin-2 methylase	234
646768521	584	52.96	333	584	2	244	4.0e-87	315	COG1010	Precorrin-3B methylase	249
646768522	873	18.46	1	856	1	885	7.0e-14	73.2	COG0419	DNA repair exonuclease SbcCD ATPase subunit	908
646768523	400	19.08	2	365	1	384	2.0e-16	80.2	COG0420	DNA repair exonuclease SbcCD nuclease subunit	390
646768524	426	45.82	1	419	1	415	5.0e-111	394	COG2733	Uncharacterized membrane-anchored protein YjiN, DUF445 family	415
646768525	657	27.64	20	388	11	354	4.0e-43	170	COG0628	Predicted PurR-regulated permease PerM	355
646768526	1318	21.64	749	1318	1	600	2.0e-12	69	COG3468	Type V secretory pathway, adhesin AidA	644
646768528	578	22.74	33	417	5	378	5.0e-43	169	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
646768532	327	26.91	1	325	1	307	1.0e-56	214	COG1893	Ketopantoate reductase	307
646768533	264	26.29	18	228	1	206	9.0e-37	147	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
646768534	399	57.07	1	396	1	396	0.0e+00	550	COG1448	Aspartate/tyrosine/aromatic aminotransferase	396
646768535	313	28.33	7	303	2	297	6.0e-29	121	COG0583	DNA-binding transcriptional regulator, LysR family	297
646768536	274	38.98	215	273	3	61	2.0e-07	50	COG2771	DNA-binding transcriptional regulator, CsgD family	65
646768537	375	31.34	103	366	73	332	6.0e-33	135	COG0642	Signal transduction histidine kinase	336
646768539	281	30.47	16	281	1	266	5.0e-39	155	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
646768540	1193	37.37	446	725	68	335	8.0e-39	156	COG0642	Signal transduction histidine kinase	336
646768541	706	58.66	24	531	1	496	0.0e+00	695	COG0753	Catalase	496
646768542	299	25.32	69	299	32	258	2.0e-26	113	COG3713	Outer membrane scaffolding protein for murein synthesis, MipA/OmpV family	258
646768543	252	48.57	62	235	1	174	2.0e-57	215	COG0225	Peptide methionine sulfoxide reductase MsrA	174
646768544	168	42.67	19	168	6	154	9.0e-31	126	COG1522	DNA-binding transcriptional regulator, Lrp family	154
646768545	338	53.73	1	335	1	323	5.0e-114	404	COG2515	1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase, PLP-dependent ACC family	323
646768546	303	32.67	1	295	1	296	8.0e-40	157	COG0583	DNA-binding transcriptional regulator, LysR family	297
646768547	241	37.05	1	240	1	251	3.0e-48	185	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
646768548	137	41.86	10	137	12	136	6.0e-18	83.1	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
646768549	278	28.11	29	277	1	229	2.0e-19	90	COG2801	Transposase InsO and inactivated derivatives	232
646768551	530	72.73	1	513	1	516	0.0e+00	816	COG3634	Alkyl hydroperoxide reductase subunit AhpF	520
646768552	187	50	1	184	2	188	2.0e-67	248	COG0450	Alkyl hydroperoxide reductase subunit AhpC (peroxiredoxin)	194
646768553	673	38.29	79	672	3	555	1.0e-120	427	COG3829	Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding Fis domains	560
646768554	294	44.79	5	292	3	289	2.0e-69	255	COG2513	2-Methylisocitrate lyase and related enzymes, PEP mutase family	289
646768555	479	20	1	415	1	357	9.0e-14	71.8	COG2814	Predicted arabinose efflux permease, MFS family	394
646768558	161	26.27	4	115	5	122	9.0e-06	43.4	COG3631	Ketosteroid isomerase-related protein	133
646768559	525	22.62	10	428	1	361	3.0e-10	60.6	COG2814	Predicted arabinose efflux permease, MFS family	394
646768560	293	30.48	4	289	1	288	1.0e-23	103	COG0583	DNA-binding transcriptional regulator, LysR family	297
646768561	152	38.53	41	149	2	110	3.0e-20	91.5	COG2005	DNA-binding transcriptional regulator ModE (molybdenum-dependent)	130
646768563	479	23.01	16	474	12	404	2.0e-58	220	COG1488	Nicotinic acid phosphoribosyltransferase	405
646768564	400	25.52	49	385	44	356	1.0e-33	137	COG4963	Flp pilus assembly protein, ATPase CpaE	366
646768566	475	41.08	11	456	4	464	2.0e-112	400	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
646768567	878	30.19	515	818	1	300	2.0e-32	134	COG0668	Small-conductance mechanosensitive channel	316
646768568	753	22.64	175	751	8	632	3.0e-59	223	COG1199	Rad3-related DNA helicase	654
646768570	194	19.25	1	190	1	213	1.0e-08	53	COG1556	L-lactate utilization protein LutC, contains LUD domain	218
646768571	467	41.55	34	456	31	459	2.0e-112	399	COG1139	L-lactate utilization protein LutB, contains a ferredoxin-type domain	459
646768573	330	43.81	5	330	1	329	1.0e-78	286	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
646768574	255	26.07	19	250	16	268	5.0e-19	88.4	COG1082	Sugar phosphate isomerase/epimerase	274
646768575	379	28.3	1	358	1	341	4.0e-45	175	COG0673	Predicted dehydrogenase	342
646768576	248	37.45	6	245	3	241	4.0e-43	168	COG2186	DNA-binding transcriptional regulator, FadR family	241
646768577	568	31.18	102	563	47	490	1.0e-70	261	COG2939	Carboxypeptidase C (cathepsin A)	498
646768580	416	41.78	43	415	12	393	4.0e-93	335	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
646768581	494	39.31	1	494	2	443	5.0e-122	431	COG1508	DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog	444
646768587	190	33.54	29	187	8	170	3.0e-12	65.5	COG3652	Predicted outer membrane protein	170
646768588	183	38.83	7	183	2	188	2.0e-27	115	COG0693	Putative intracellular protease/amidase	188
646768590	428	45.27	18	361	12	354	1.0e-84	307	COG3569	DNA topoisomerase IB	354
646768595	382	35.39	21	369	3	355	2.0e-59	223	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
646768596	405	28.27	2	405	10	381	3.0e-32	133	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
646768597	475	29.81	18	470	1	459	1.0e-82	300	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
646768599	326	32.46	210	323	14	127	2.0e-16	79.9	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
646768600	113	37.5	9	104	18	113	3.0e-13	67	COG0599	Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family	124
646768601	335	24.63	28	297	1	252	1.0e-24	107	COG3000	Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily	271
646768603	351	47.72	1	326	1	314	2.0e-86	312	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
646768604	1509	36.93	36	933	1	809	0.0e+00	714	COG1201	Lhr-like helicase	814
646768606	367	40.62	9	356	1	347	2.0e-86	312	COG2055	Malate/lactate/ureidoglycolate dehydrogenase, LDH2 family	349
646768607	499	21.38	37	495	10	403	3.0e-24	106	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
646768611	209	24.62	15	208	4	196	2.0e-08	52.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
646768612	141	39.29	4	140	9	143	5.0e-22	96.9	COG1764	Organic hydroperoxide reductase OsmC/OhrA	143
646768615	442	43.64	6	442	20	448	0.0e+00	495	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
646768616	284	31.91	4	280	1	280	2.0e-37	149	COG1737	DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains	281
646768620	294	46.15	1	293	1	298	5.0e-80	291	COG3246	Uncharacterized conserved protein, DUF849 family	298
646768621	468	40.39	3	456	16	469	1.0e-108	386	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
646768622	98	36.46	1	95	1	95	2.0e-13	67.6	COG5470	Uncharacterized conserved protein, DUF1330 family	96
646768623	258	37.25	1	250	2	255	2.0e-38	152	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
646768624	428	34.99	1	399	4	396	7.0e-73	268	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
646768625	454	17.45	21	433	20	433	9.0e-16	78.7	COG2271	Sugar phosphate permease	448
646768626	273	17.65	55	241	14	200	9.0e-06	44.3	COG1309	DNA-binding transcriptional regulator, AcrR family	201
646768629	394	42.79	4	392	2	390	1.0e-72	267	COG0183	Acetyl-CoA acetyltransferase	392
646768630	561	50.47	34	553	4	529	0.0e+00	463	COG4147	Na+(or H+)/acetate symporter ActP	529
646768631	105	44.79	8	103	8	102	4.0e-17	79.5	COG3162	Uncharacterized membrane protein, DUF485 family	102
646768632	324	52.74	1	324	1	311	1.0e-81	296	COG2025	Electron transfer flavoprotein, alpha subunit	313
646768633	249	51.15	1	249	1	260	1.0e-70	259	COG2086	Electron transfer flavoprotein, alpha and beta subunits	260
646768634	328	33.23	4	324	1	331	3.0e-46	179	COG2070	NAD(P)H-dependent flavin oxidoreductase YrpB, nitropropane dioxygenase family	336
646768635	403	43.75	3	401	1	395	1.0e-105	377	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
646768636	270	37.74	1	256	3	256	2.0e-43	169	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
646768637	376	29.58	1	369	1	381	2.0e-44	173	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
646768638	401	34.06	1	401	1	389	3.0e-64	239	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
646768639	393	36.76	1	391	1	390	3.0e-70	259	COG0183	Acetyl-CoA acetyltransferase	392
646768640	705	38.89	297	598	1	306	1.0e-74	275	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
646768641	303	27.54	1	300	1	296	3.0e-33	135	COG0583	DNA-binding transcriptional regulator, LysR family	297
646768642	238	25.35	27	238	83	290	1.0e-13	70	COG0583	DNA-binding transcriptional regulator, LysR family	297
646768644	443	29.01	1	440	1	455	6.0e-76	278	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
646768645	315	41.51	3	315	12	328	3.0e-68	252	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
646768646	427	14.69	109	426	1	282	3.0e-08	53.6	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
646768647	347	23.63	57	346	5	280	6.0e-19	88.6	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
646768648	150	37.91	1	150	10	159	4.0e-25	107	COG2030	Acyl dehydratase	159
646768650	240	24.79	3	236	1	228	7.0e-25	107	COG1011	FMN phosphatase YigB, HAD superfamily	229
646768651	373	38.07	22	366	7	355	1.0e-57	217	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
646768652	335	34.63	1	335	1	335	1.0e-81	296	COG3938	Proline racemase	341
646768655	760	29.26	46	737	23	641	3.0e-97	350	COG3408	Glycogen debranching enzyme (alpha-1,6-glucosidase)	641
646768656	432	51.85	29	432	1	390	0.0e+00	492	COG0372	Citrate synthase	390
646768658	286	27.27	14	283	1	282	5.0e-21	95.2	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
646768659	350	50.15	11	341	1	331	3.0e-96	345	COG1077	Actin-like ATPase involved in cell morphogenesis	342
646768660	224	28.29	17	219	12	207	3.0e-24	105	COG0400	Predicted esterase	207
646768662	262	35.83	144	262	1	120	2.0e-18	86.5	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
646768663	289	26.67	1	225	2	223	2.0e-19	89.6	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
646768664	289	25.18	20	289	6	281	1.0e-25	110	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
646768665	520	37.77	131	518	2	408	3.0e-46	180	COG0840	Methyl-accepting chemotaxis protein	408
646768666	248	40.94	2	247	1	251	3.0e-48	185	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
646768667	181	20.44	26	156	3	135	5.0e-08	51.1	COG2703	Hemerythrin	144
646768669	369	29.3	1	363	1	334	9.0e-44	171	COG1064	D-arabinose 1-dehydrogenase, Zn-dependent alcohol dehydrogenase family	339
646768670	365	22.54	1	365	1	354	2.0e-31	129	COG3203	Outer membrane protein (porin)	354
646768671	339	24.78	5	336	1	341	2.0e-58	219	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
646768672	313	76.04	1	313	1	307	3.0e-125	441	COG4569	Acetaldehyde dehydrogenase (acetylating)	310
646768673	265	45.04	4	264	1	261	4.0e-69	254	COG3971	2-keto-4-pentenoate hydratase	264
646768676	281	28.42	13	273	5	279	9.0e-28	117	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
646768678	480	35.48	7	480	3	472	3.0e-84	306	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
646768680	442	21.87	33	391	17	373	4.0e-17	82.9	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
646768681	342	26.69	105	338	3	230	3.0e-31	129	COG1018	Ferredoxin-NADP reductase	266
646768682	468	35.44	5	465	2	475	1.0e-100	360	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
646768683	453	20.66	39	424	24	367	5.0e-16	79.4	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
646768684	328	35.35	226	324	22	117	5.0e-17	81.8	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
646768685	556	32.54	10	537	3	525	1.0e-100	360	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
646768697	584	24.56	231	563	1	283	1.0e-26	115	COG4974	Site-specific recombinase XerD	300
646768699	408	28.08	14	393	14	390	1.0e-26	114	COG2814	Predicted arabinose efflux permease, MFS family	394
646768700	199	27.27	69	189	4	124	2.0e-13	69.2	COG1846	DNA-binding transcriptional regulator, MarR family	126
646768701	568	36.29	169	525	30	408	2.0e-39	157	COG0840	Methyl-accepting chemotaxis protein	408
646768702	423	38.84	11	368	10	350	4.0e-70	259	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
646768703	274	35.55	15	264	1	251	4.0e-39	155	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
646768704	113	26.79	7	113	4	102	4.0e-06	43.4	COG2863	Cytochrome c553	121
646768705	559	21.13	18	546	1	455	4.0e-31	130	COG0277	FAD/FMN-containing dehydrogenase	459
646768707	268	40.93	5	253	1	251	3.0e-37	149	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
646768708	489	48.51	17	484	1	465	0.0e+00	515	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
646768709	336	23.96	25	299	9	275	6.0e-21	94.9	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
646768710	334	31.48	5	321	2	323	1.0e-47	183	COG2423	Ornithine cyclodeaminase/archaeal alanine dehydrogenase, mu-crystallin family	330
646768711	177	38.18	5	168	23	187	1.0e-37	149	COG2353	Polyisoprenoid-binding periplasmic protein YceI	192
646768712	222	36.56	1	218	9	231	6.0e-30	124	COG2186	DNA-binding transcriptional regulator, FadR family	241
646768713	309	43.28	1	304	2	298	9.0e-84	303	COG3246	Uncharacterized conserved protein, DUF849 family	298
646768714	370	27.96	3	360	1	367	6.0e-44	171	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
646768719	101	30.69	1	101	14	106	2.0e-09	54.2	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
646768720	311	21.69	9	303	1	292	2.0e-27	116	COG0583	DNA-binding transcriptional regulator, LysR family	297
646768721	354	25.92	1	340	22	361	1.0e-36	147	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
646768722	316	32.09	1	255	5	266	8.0e-42	164	COG1018	Ferredoxin-NADP reductase	266
646768723	389	19.89	40	383	43	394	2.0e-08	54.1	COG2814	Predicted arabinose efflux permease, MFS family	394
646768724	207	19.6	7	201	3	201	3.0e-06	45.8	COG1309	DNA-binding transcriptional regulator, AcrR family	201
646768725	159	29.46	29	157	13	141	3.0e-17	81.2	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
646768726	335	31.39	50	321	6	265	1.0e-40	160	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
646768727	146	50.68	1	145	3	150	3.0e-43	167	COG3241	Azurin	151
646768729	355	18.77	11	353	9	332	2.0e-21	96.7	COG4447	Uncharacterized protein related to plant photosystem II stability/assembly factor	339
646768730	804	20.18	23	788	5	726	2.0e-83	304	COG1033	Predicted exporter protein, RND superfamily	727
646768732	327	35.45	29	327	5	263	6.0e-58	217	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
646768733	463	21.41	10	390	24	408	4.0e-20	93	COG2271	Sugar phosphate permease	448
646768735	539	24.23	2	348	1	347	1.0e-44	174	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
646768736	434	62.44	11	428	4	420	0.0e+00	539	COG3508	Homogentisate 1,2-dioxygenase	427
646768737	328	25.85	4	327	1	266	2.0e-37	149	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
646768738	262	37.8	11	255	1	244	4.0e-40	158	COG1414	DNA-binding transcriptional regulator, IclR family	246
646768750	279	39	99	193	1	100	3.0e-17	82.6	COG1695	DNA-binding transcriptional regulator, PadR family	138
646768751	278	43.89	14	273	10	265	4.0e-58	218	COG2375	NADPH-dependent ferric siderophore reductase, contains FAD-binding and SIP domains	265
646768752	428	31.53	1	406	3	394	1.0e-46	180	COG2814	Predicted arabinose efflux permease, MFS family	394
646768753	364	27.95	8	353	13	355	5.0e-32	131	COG0628	Predicted PurR-regulated permease PerM	355
646768757	390	30.74	23	278	7	255	2.0e-34	140	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
646768758	266	42.64	1	255	4	257	2.0e-45	176	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
646768759	305	50.17	1	292	1	286	2.0e-80	292	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
646768760	513	39.38	20	496	1	469	2.0e-118	419	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
646768761	563	33.78	29	542	1	522	1.0e-119	424	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
646768762	423	48.45	47	423	1	386	3.0e-96	345	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
646768763	375	29.59	263	359	23	119	6.0e-13	68.7	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
646768764	561	41.59	230	548	117	431	1.0e-69	258	COG1030	Membrane-bound serine protease (ClpP class)	436
646768765	256	37.33	4	256	1	291	2.0e-36	146	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
646768767	164	57.53	1	146	2	145	3.0e-43	167	COG1671	Uncharacterized conserved protein YaiI, UPF0178 family	150
646768768	433	54.38	1	431	3	436	3.0e-117	415	COG2252	Xanthine/uracil/vitamin C permease, AzgA family	436
646768769	177	39.08	7	177	4	177	9.0e-27	113	COG3038	Cytochrome b561	181
646768771	102	23.6	9	93	7	95	4.0e-08	49.7	COG0633	Ferredoxin	102
646768774	214	27.06	7	214	4	219	6.0e-44	170	COG2964	Predicted transcriptional regulator YheO, contains PAS and DNA-binding HTH domains	220
646768777	92	56.76	1	74	1	74	8.0e-20	88.7	COG0361	Translation initiation factor IF-1	75
646768778	191	37.37	1	190	5	194	2.0e-31	129	COG3707	Two-component response regulator, AmiR/NasT family, consists of REC and RNA-binding antiterminator (ANTAR) domains	194
646768779	383	31.08	4	319	16	329	2.0e-43	170	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
646768780	336	28.57	6	298	6	298	6.0e-33	134	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
646768781	341	40.39	22	326	13	316	2.0e-46	179	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
646768782	351	41.9	30	343	5	316	2.0e-53	203	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
646768783	509	55.42	5	500	3	500	0.0e+00	622	COG1129	ABC-type sugar transport system, ATPase component	500
646768784	297	31.65	1	296	7	277	2.0e-49	189	COG3618	Predicted metal-dependent hydrolase, TIM-barrel fold	279
646768785	105	45.19	1	103	1	104	5.0e-26	109	COG3254	L-rhamnose mutarotase	105
646768786	331	31.02	14	315	1	297	5.0e-26	112	COG0583	DNA-binding transcriptional regulator, LysR family	297
646768787	260	41.15	1	255	1	250	1.0e-44	173	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
646768788	392	35.49	39	384	11	362	9.0e-63	234	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
646768789	250	37.8	4	248	1	251	3.0e-45	175	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
646768795	212	32.88	4	143	2	136	5.0e-17	81.1	COG0394	Protein-tyrosine-phosphatase	139
646768797	278	25.53	56	241	3	179	2.0e-14	73.5	COG0431	NAD(P)H-dependent FMN reductase	184
646768799	484	36.49	6	482	2	473	7.0e-77	281	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
646768800	262	33.2	14	259	4	250	3.0e-39	155	COG2134	CDP-diacylglycerol pyrophosphatase	252
646768801	330	22.18	15	286	24	301	5.0e-24	105	COG3239	Fatty acid desaturase	343
646768803	312	25.66	1	303	1	288	1.0e-28	120	COG0053	Divalent metal cation (Fe/Co/Zn/Cd) transporter	304
646768805	223	28.11	47	223	5	185	2.0e-11	62.7	COG0778	Nitroreductase	207
646768806	277	30.32	1	269	1	248	3.0e-36	145	COG0121	Predicted glutamine amidotransferase	252
646768808	430	28.85	19	424	14	405	2.0e-49	190	COG1914	Mn2+ and Fe2+ transporters of the NRAMP family	416
646768810	799	47.97	533	778	2	245	3.0e-76	280	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
646768811	303	26.03	7	297	1	291	4.0e-28	118	COG0583	DNA-binding transcriptional regulator, LysR family	297
646768812	277	38.63	1	272	5	277	6.0e-61	227	COG0169	Shikimate 5-dehydrogenase	283
646768813	406	43.61	3	400	5	396	6.0e-99	354	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
646768814	153	35.81	7	151	15	159	9.0e-21	92.9	COG2030	Acyl dehydratase	159
646768816	316	40.13	1	304	1	301	1.0e-63	236	COG1893	Ketopantoate reductase	307
646768819	257	40.94	8	254	1	251	2.0e-46	179	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
646768822	197	43.98	6	196	29	219	4.0e-45	174	COG4318	Uncharacterized protein	221
646768823	173	28.97	1	144	1	131	2.0e-17	82.3	COG3521	Predicted component of the type VI protein secretion system	159
646768824	378	34.12	13	347	4	317	8.0e-53	201	COG3520	Predicted component of the type VI protein secretion system	335
646768825	604	34.7	4	604	2	621	3.0e-123	435	COG3519	Type VI protein secretion system component VasA	621
646768827	1194	21.63	19	1150	18	1188	2.0e-74	274	COG3523	Type VI protein secretion system component VasK	1188
646768829	843	33.33	612	836	9	200	1.0e-28	122	COG3179	Predicted chitinase	206
646768830	778	25.69	18	537	22	537	1.0e-61	231	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
646768831	523	50.8	18	518	7	495	0.0e+00	644	COG3517	Predicted component of the type VI protein secretion system	495
646768832	170	49.38	3	162	6	167	1.0e-40	159	COG3516	Predicted component of the type VI protein secretion system	169
646768833	450	30.91	1	450	2	446	1.0e-77	284	COG3522	Predicted component of the type VI protein secretion system	446
646768834	243	29.54	9	238	26	254	7.0e-24	104	COG3455	Type VI protein secretion system component VasF	262
646768837	161	33.13	1	160	1	157	3.0e-32	131	COG3157	Type VI protein secretion system component Hcp (secreted cytotoxin)	162
646768838	905	42.37	20	869	1	764	0.0e+00	760	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
646768839	141	29.41	5	127	9	137	2.0e-13	68.4	COG3518	Predicted component of the type VI protein secretion system	157
646768841	430	34.79	53	430	44	427	9.0e-45	174	COG0025	NhaP-type Na+/H+ or K+/H+ antiporter	429
646768843	263	25.57	48	259	84	299	9.0e-23	100	COG3221	ABC-type phosphate/phosphonate transport system, periplasmic component	299
646768844	689	54.47	1	683	1	644	0.0e+00	810	COG4770	Acetyl/propionyl-CoA carboxylase, alpha subunit	645
646768845	262	39.85	1	260	2	257	1.0e-45	176	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
646768846	535	44.96	12	535	1	526	0.0e+00	658	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component	526
646768847	393	42.09	7	389	1	387	5.0e-94	338	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
646768848	245	20.71	14	209	3	200	4.0e-09	55.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
646768849	307	32.69	48	303	2	258	2.0e-51	196	COG1801	Uncharacterized conserved protein YecE, DUF72 family	263
646768850	372	65.23	24	371	4	351	0.0e+00	556	COG0722	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase	351
646768851	92	52.17	1	92	2	93	9.0e-24	101	COG0776	Bacterial nucleoid DNA-binding protein	94
646768853	657	46.13	6	638	9	641	0.0e+00	604	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
646768854	237	34.09	22	232	9	226	7.0e-53	200	COG4312	Predicted dithiol-disulfide oxidoreductase, DUF899 family	247
646768855	315	27.52	6	298	1	293	2.0e-29	123	COG0583	DNA-binding transcriptional regulator, LysR family	297
646768856	426	21.91	52	404	42	382	3.0e-13	69.8	COG2814	Predicted arabinose efflux permease, MFS family	394
646768857	201	27.45	34	183	25	177	5.0e-20	91	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
646768858	138	42.62	9	130	12	132	1.0e-25	108	COG4101	Uncharacterized protein, RmlC-like cupin domain	142
646768859	339	28.19	13	200	19	206	7.0e-23	101	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
646768860	255	40.95	2	233	19	241	1.0e-59	223	COG2071	Gamma-glutamyl-gamma-aminobutyrate hydrolase PuuD (putrescine degradation), contains GATase1-like domain	243
646768861	444	37.69	3	441	5	441	2.0e-117	416	COG0174	Glutamine synthetase	443
646768862	485	44.07	39	480	7	447	0.0e+00	498	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
646768863	244	22.09	5	235	24	280	1.0e-14	74	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
646768864	243	57.56	3	240	1	221	2.0e-64	238	COG5634	Uncharacterized protein YukJ	223
646768865	472	17.78	69	465	49	439	3.0e-14	73.7	COG2271	Sugar phosphate permease	448
646768866	547	28.92	24	547	6	531	1.0e-84	307	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
646768867	305	30.27	4	296	2	289	1.0e-29	123	COG0583	DNA-binding transcriptional regulator, LysR family	297
646768869	794	33.25	4	791	4	784	0.0e+00	606	COG0417	DNA polymerase elongation subunit (family B)	792
646768871	802	44.57	100	799	37	709	0.0e+00	699	COG2217	Cation transport ATPase	713
646768873	274	25.22	17	241	61	258	1.0e-25	110	COG1864	DNA/RNA endonuclease G, NUC1	281
646768875	651	34.16	202	641	2	417	9.0e-83	301	COG0065	Homoaconitase/3-isopropylmalate dehydratase large subunit	423
646768876	300	34.36	8	296	1	287	9.0e-31	127	COG0583	DNA-binding transcriptional regulator, LysR family	297
646768877	242	71.49	15	242	9	236	9.0e-96	343	COG3826	Uncharacterized protein	236
646768878	215	40.09	5	213	6	216	2.0e-51	195	COG2761	Predicted dithiol-disulfide isomerase, DsbA family	225
646768880	106	46.74	15	106	3	94	9.0e-28	115	COG3123	Uncharacterized conserved protein YaiE, UPF0345 family	94
646768884	401	32.5	2	400	18	413	3.0e-65	242	COG2995	Uncharacterized paraquat-inducible protein A	418
646768886	211	31.52	30	209	8	187	5.0e-10	58.1	COG3009	Uncharacterized lipoprotein YmbA	190
646768887	329	27.03	30	140	10	120	4.0e-11	62.6	COG1846	DNA-binding transcriptional regulator, MarR family	126
646768890	265	32.73	24	243	4	210	2.0e-33	136	COG1802	DNA-binding transcriptional regulator, GntR family	230
646768891	435	28.23	128	420	1	288	2.0e-27	117	COG0583	DNA-binding transcriptional regulator, LysR family	297
646768892	711	33.47	161	390	33	271	5.0e-12	66.5	COG0457	Tetratricopeptide (TPR) repeat	291
646768894	789	20.2	28	783	7	693	1.0e-38	155	COG4771	Outer membrane receptor for ferrienterochelin and colicins	699
646768895	501	39.53	29	495	5	439	2.0e-79	289	COG3182	Uncharacterized iron-regulated membrane protein	442
646768896	264	36.76	12	263	1	253	1.0e-49	190	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
646768898	288	26.1	22	265	19	264	6.0e-18	84.8	COG3000	Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily	271
646768899	314	31.9	78	303	49	277	9.0e-27	114	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
646768902	110	47.62	6	109	1	105	3.0e-32	130	COG4390	Uncharacterized protein	106
646768904	283	36	10	282	7	281	5.0e-56	211	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
646768905	324	40.07	45	324	6	292	1.0e-58	220	COG1175	ABC-type sugar transport system, permease component	295
646768906	417	25.52	1	417	2	432	2.0e-40	160	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
646768907	659	34.11	3	657	18	671	3.0e-130	459	COG1874	Beta-galactosidase GanA	673
646768908	383	47.97	1	369	1	338	6.0e-119	420	COG3839	ABC-type sugar transport system, ATPase component	338
646768909	347	42.07	2	345	1	333	5.0e-72	264	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
646768910	402	22.03	8	401	7	392	2.0e-06	47.5	COG2814	Predicted arabinose efflux permease, MFS family	394
646768911	333	33.01	20	325	18	322	6.0e-45	174	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
646768912	329	42.49	19	329	5	313	8.0e-54	204	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
646768914	414	27.12	92	391	4	306	1.0e-34	141	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
646768916	312	28.28	12	307	1	290	5.0e-27	115	COG0583	DNA-binding transcriptional regulator, LysR family	297
646768917	310	29.93	10	300	5	292	5.0e-41	161	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
646768918	429	30.39	20	391	1	377	2.0e-48	186	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
646768919	246	25.43	39	210	4	176	5.0e-11	61.6	COG1309	DNA-binding transcriptional regulator, AcrR family	201
646768920	455	20.09	13	451	7	441	5.0e-22	99.5	COG2271	Sugar phosphate permease	448
646768921	312	40.97	28	311	1	282	4.0e-69	255	COG0169	Shikimate 5-dehydrogenase	283
646768922	151	56.55	5	149	2	146	6.0e-57	213	COG0757	3-dehydroquinate dehydratase	146
646768923	629	41.91	287	629	13	356	8.0e-93	334	COG3185	4-hydroxyphenylpyruvate dioxygenase and related hemolysins	363
646768927	255	38.84	130	249	2	122	6.0e-20	91.5	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
646768928	430	25	1	314	1	338	2.0e-21	97.6	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
646768930	383	30.4	1	379	3	384	7.0e-36	145	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
646768931	318	39.64	1	316	1	333	2.0e-83	302	COG3938	Proline racemase	341
646768932	235	32.3	1	225	1	225	3.0e-38	152	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
646768933	433	19.88	80	426	63	384	2.0e-07	50.6	COG2814	Predicted arabinose efflux permease, MFS family	394
646768936	144	37.12	9	139	15	141	5.0e-13	66.9	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
646768937	135	27.66	8	131	3	138	1.0e-07	48.7	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
646768938	154	49.32	1	146	1	141	9.0e-46	176	COG4154	L-fucose mutarotase/ribose pyranase, RbsD/FucU family	144
646768941	129	48.91	30	121	4	95	1.0e-24	105	COG3657	Putative component of the toxin-antitoxin plasmid stabilization module	100
646768942	100	43.88	1	98	3	100	1.0e-18	85	COG3636	DNA-binding prophage protein	100
646768944	178	21.02	6	178	8	180	1.0e-10	60	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
646768947	442	47.04	19	439	1	413	2.0e-83	303	COG1914	Mn2+ and Fe2+ transporters of the NRAMP family	416
646768948	399	22.5	13	394	10	392	3.0e-33	136	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
646768949	542	39.32	79	516	24	456	5.0e-58	219	COG1538	Outer membrane protein TolC	457
646768950	1061	47.55	2	1039	1	1009	0.0e+00	1003	COG0841	Multidrug efflux pump subunit AcrB	1009
646768951	407	32.71	6	374	1	366	2.0e-32	133	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
646768952	288	36.03	21	287	41	312	6.0e-38	151	COG0657	Acetyl esterase/lipase	312
646768953	334	32.89	3	298	2	295	8.0e-39	154	COG0583	DNA-binding transcriptional regulator, LysR family	297
646768955	326	47.85	1	324	1	315	8.0e-92	330	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
646768956	301	24.74	7	297	13	288	3.0e-31	129	COG0053	Divalent metal cation (Fe/Co/Zn/Cd) transporter	304
646768957	1612	48.64	35	1612	34	1591	0.0e+00	1648	COG2902	NAD-specific glutamate dehydrogenase	1592
646768958	290	20.85	51	272	60	294	8.0e-07	48.1	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
646768962	281	25.58	145	271	1	122	5.0e-07	48.6	COG3293	Transposase	124
646768966	296	50	7	260	3	252	1.0e-82	299	COG3638	ABC-type phosphate/phosphonate transport system, ATPase component	258
646768967	325	37.19	6	285	13	291	3.0e-59	222	COG3221	ABC-type phosphate/phosphonate transport system, periplasmic component	299
646768968	279	44.74	20	279	17	282	1.0e-66	247	COG3639	ABC-type phosphate/phosphonate transport system, permease component	283
646768970	178	27.07	14	146	12	137	4.0e-15	74.5	COG0824	Acyl-CoA thioesterase FadM	137
646768971	330	33.86	12	327	13	310	5.0e-40	158	COG0657	Acetyl esterase/lipase	312
646768974	224	39.09	1	219	1	219	8.0e-37	147	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
646768975	386	22.28	1	386	1	354	1.0e-35	144	COG3203	Outer membrane protein (porin)	354
646768976	293	25.68	2	293	1	289	4.0e-17	82.4	COG0583	DNA-binding transcriptional regulator, LysR family	297
646768977	250	45.75	1	244	4	249	5.0e-51	194	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
646768979	217	27.75	10	206	43	244	6.0e-24	104	COG1360	Flagellar motor protein MotB	244
646768982	410	25.53	1	410	3	381	4.0e-37	149	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
646768983	769	43.68	44	769	29	750	0.0e+00	700	COG4774	Outer membrane receptor for monomeric catechols	750
646768984	274	26.85	1	210	29	244	3.0e-20	92.4	COG0790	TPR repeat	292
646768985	227	57.71	1	226	3	228	1.0e-83	302	COG3128	Predicted 2-oxoglutarate- and Fe(II)-dependent dioxygenase YbiX	229
646768986	493	23.99	7	491	1	489	2.0e-39	157	COG0591	Na+/proline symporter	493
646768988	471	44.08	1	456	1	447	3.0e-123	435	COG4564	Signal transduction histidine kinase	459
646768989	217	43	11	213	2	207	9.0e-46	176	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
646768991	646	24.61	42	614	1	443	7.0e-53	202	COG3119	Arylsulfatase A or related enzyme	475
646768992	363	29.18	73	360	40	312	3.0e-32	132	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
646768993	264	37.97	1	264	3	268	4.0e-57	215	COG1464	ABC-type metal ion transport system, periplasmic component/surface antigen	268
646768995	424	33.49	8	420	2	434	8.0e-68	251	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
646769005	220	30.53	10	195	2	190	4.0e-21	95	COG1407	Metallophosphoesterase superfamily enzyme	235
646769007	462	19.31	25	460	13	458	1.0e-38	154	COG0277	FAD/FMN-containing dehydrogenase	459
646769008	196	31.46	24	191	6	181	7.0e-30	123	COG2930	Lipid-binding SYLF domain	227
646769009	519	38.42	175	515	42	408	5.0e-51	195	COG0840	Methyl-accepting chemotaxis protein	408
646769010	190	24.11	43	183	14	150	8.0e-17	80.3	COG2606	Cys-tRNA(Pro) deacylase, prolyl-tRNA editing enzyme YbaK/EbsC	155
646769011	423	32.62	15	292	13	291	2.0e-31	130	COG1295	Uncharacterized membrane protein, BrkB/YihY/UPF0761 family (not an RNase)	303
646769012	395	19.7	8	395	4	354	5.0e-40	158	COG3203	Outer membrane protein (porin)	354
646769013	290	55.2	1	249	1	250	4.0e-95	341	COG3484	Predicted proteasome-type protease	255
646769014	266	30.99	1	252	11	294	1.0e-30	127	COG1305	Transglutaminase-like enzyme, putative cysteine protease	319
646769015	316	38.87	1	314	1	310	3.0e-68	252	COG2307	Uncharacterized conserved protein, Alpha-E superfamily	313
646769016	469	61.67	4	469	12	477	0.0e+00	655	COG2308	Uncharacterized conserved protein, circularly permuted ATPgrasp superfamily	488
646769018	495	39.18	13	490	5	453	8.0e-98	351	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
646769019	145	36.84	15	145	44	176	1.0e-20	92.2	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
646769021	311	34.53	1	306	1	302	6.0e-62	231	COG1893	Ketopantoate reductase	307
646769023	473	30.44	28	473	8	455	7.0e-43	168	COG1538	Outer membrane protein TolC	457
646769025	366	38.66	11	365	1	348	2.0e-68	253	COG1566	Multidrug resistance efflux pump	352
646769026	140	26.23	13	134	1	122	7.0e-09	53.4	COG1846	DNA-binding transcriptional regulator, MarR family	126
646769027	140	25.62	16	136	1	121	9.0e-09	52.6	COG1846	DNA-binding transcriptional regulator, MarR family	126
646769028	321	28.7	2	321	12	323	3.0e-37	149	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
646769032	309	31.16	12	301	3	290	1.0e-36	147	COG0583	DNA-binding transcriptional regulator, LysR family	297
646769035	302	30.67	6	300	1	297	6.0e-33	134	COG0583	DNA-binding transcriptional regulator, LysR family	297
646769037	250	52.28	5	244	2	232	4.0e-75	274	COG3910	Predicted ATPase	233
646769038	297	31.71	8	289	13	298	1.0e-37	150	COG1305	Transglutaminase-like enzyme, putative cysteine protease	319
646769039	862	44.33	19	500	12	488	3.0e-130	460	COG2308	Uncharacterized conserved protein, circularly permuted ATPgrasp superfamily	488
646769040	1161	49.72	286	1161	3	805	0.0e+00	874	COG4196	Uncharacterized conserved protein, DUF2126 family	808
646769041	401	56.45	36	384	1	334	0.0e+00	492	COG4307	Uncharacterized protein	349
646769047	736	20.26	26	736	1	768	7.0e-30	126	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
646769049	165	29.05	1	140	2	149	1.0e-08	53.1	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
646769050	601	34.02	9	437	6	443	2.0e-60	227	COG0038	H+/Cl- antiporter ClcA	443
646769053	388	49.87	1	387	4	382	9.0e-106	377	COG3448	CBS-domain-containing membrane protein	382
646769055	599	37.64	6	437	3	443	1.0e-64	241	COG0038	H+/Cl- antiporter ClcA	443
646769057	300	30.53	1	279	1	274	2.0e-34	139	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
646769059	251	36.32	18	240	21	225	4.0e-21	95.4	COG2801	Transposase InsO and inactivated derivatives	232
646769061	414	27.74	1	413	3	382	7.0e-40	158	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
646769062	262	35.23	5	262	11	270	2.0e-38	152	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
646769063	323	29.65	10	320	5	321	3.0e-52	198	COG2423	Ornithine cyclodeaminase/archaeal alanine dehydrogenase, mu-crystallin family	330
646769064	214	28.24	5	211	2	217	4.0e-47	181	COG2964	Predicted transcriptional regulator YheO, contains PAS and DNA-binding HTH domains	220
646769065	169	28.05	1	163	12	170	9.0e-14	70.1	COG3652	Predicted outer membrane protein	170
646769067	441	33.02	14	430	1	381	4.0e-51	195	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
646769068	244	28.89	149	236	30	116	3.0e-09	55.7	COG3450	Predicted enzyme of the cupin superfamily	116
646769070	609	43.15	1	533	3	539	0.0e+00	551	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
646769071	318	38.26	49	310	18	281	4.0e-51	195	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
646769072	318	39.81	7	318	3	316	5.0e-77	281	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
646769073	532	24.5	21	530	5	556	2.0e-67	249	COG0747	ABC-type transport system, periplasmic component	556
646769074	424	25.96	26	403	5	384	3.0e-48	186	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
646769075	222	25.78	5	220	3	226	3.0e-23	101	COG1011	FMN phosphatase YigB, HAD superfamily	229
646769076	504	46.67	14	492	2	471	2.0e-124	439	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
646769077	293	21.05	9	134	7	158	2.0e-06	46.5	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
646769078	310	33.02	1	310	3	324	7.0e-63	234	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
646769079	469	40.75	4	452	3	449	0.0e+00	465	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
646769080	165	43.71	6	156	5	154	3.0e-30	124	COG1522	DNA-binding transcriptional regulator, Lrp family	154
646769081	360	50.56	3	360	1	346	2.0e-128	452	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
646769082	490	46.74	14	486	2	467	0.0e+00	501	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
646769083	325	21.52	40	314	46	321	1.0e-06	47.6	COG2988	Succinylglutamate desuccinylase	324
646769084	329	42.99	1	325	2	329	2.0e-95	342	COG1171	Threonine dehydratase	347
646769085	330	39.27	1	329	2	330	4.0e-82	298	COG2423	Ornithine cyclodeaminase/archaeal alanine dehydrogenase, mu-crystallin family	330
646769086	207	30.39	5	200	2	205	5.0e-20	91.1	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
646769087	471	33.41	15	468	4	451	2.0e-85	310	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
646769088	442	44.2	1	441	1	444	0.0e+00	494	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
646769091	402	30.77	20	376	1	361	1.0e-45	177	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
646769092	237	49.79	3	237	1	237	3.0e-78	285	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
646769093	270	44.98	1	245	2	250	2.0e-74	272	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
646769094	678	38.46	347	649	1	312	1.0e-40	161	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
646769099	133	44.35	8	128	1	124	2.0e-22	97.8	COG0599	Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family	124
646769100	263	27.11	1	260	2	280	2.0e-22	99.4	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
646769101	459	43.55	14	445	6	436	2.0e-112	399	COG0015	Adenylosuccinate lyase	438
646769102	219	49.08	1	217	3	219	1.0e-65	242	COG2057	Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit	225
646769103	235	57.66	2	223	1	220	2.0e-76	278	COG1788	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit	220
646769104	309	22.26	6	306	1	297	5.0e-28	118	COG0583	DNA-binding transcriptional regulator, LysR family	297
646769105	212	54.59	20	203	12	194	5.0e-69	253	COG0302	GTP cyclohydrolase I	195
646769106	369	28.5	12	201	15	207	1.0e-23	104	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
646769108	281	27.8	36	280	25	274	3.0e-20	92.4	COG5607	CHAD domain (function unknown)	283
646769109	197	24.5	3	179	9	208	4.0e-11	61.8	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
646769111	308	58.87	22	278	6	270	1.0e-98	353	COG2326	Polyphosphate kinase 2, PPK2 family	270
646769113	349	42.77	45	349	38	343	3.0e-57	216	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
646769115	254	25.39	1	253	4	239	5.0e-28	118	COG1213	Choline kinase	239
646769118	233	25.38	23	214	2	188	2.0e-11	63.1	COG0558	Phosphatidylglycerophosphate synthase	192
646769123	308	46.67	128	292	7	162	1.0e-42	166	COG1045	Serine acetyltransferase	194
646769126	201	23.39	1	189	5	221	2.0e-08	52.9	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
646769127	578	43.72	1	563	1	574	0.0e+00	612	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
646769128	315	34.52	50	301	11	259	6.0e-43	168	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
646769129	295	30.71	21	288	14	293	3.0e-29	122	COG1175	ABC-type sugar transport system, permease component	295
646769130	359	42.82	7	356	5	352	7.0e-102	364	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
646769131	389	22.96	31	386	5	383	5.0e-52	198	COG4134	ABC-type uncharacterized transport system YnjBCD, periplasmic component	384
646769132	314	35.79	17	314	4	291	7.0e-61	227	COG3386	Sugar lactone lactonase YvrE	307
646769133	332	19.67	15	312	8	295	6.0e-19	88.4	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
646769134	234	48.44	168	231	2	65	1.0e-14	73.9	COG2771	DNA-binding transcriptional regulator, CsgD family	65
646769136	197	42.63	1	189	1	189	3.0e-47	181	COG3916	N-acyl-L-homoserine lactone synthetase	209
646769137	229	36.68	4	226	6	231	6.0e-40	157	COG2186	DNA-binding transcriptional regulator, FadR family	241
646769138	155	38.26	1	146	4	152	2.0e-19	88.5	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
646769139	218	31.13	1	211	2	212	2.0e-32	132	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
646769140	431	29.14	141	430	13	311	7.0e-27	115	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
646769141	184	18.39	1	174	17	188	2.0e-08	52	COG1309	DNA-binding transcriptional regulator, AcrR family	201
646769142	244	25.24	28	235	1	200	2.0e-16	79.5	COG1335	Nicotinamidase-related amidase	205
646769143	218	43.56	11	212	1	202	6.0e-56	210	COG4566	Two-component response regulator, FixJ family, consists of REC and HTH domains	202
646769145	328	31.12	56	328	2	281	2.0e-32	132	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
646769146	383	36.2	1	375	3	377	7.0e-60	224	COG1749	Flagellar hook protein FlgE	423
646769147	297	22.31	49	297	1	231	3.0e-12	66.2	COG2801	Transposase InsO and inactivated derivatives	232
646769148	133	28.57	19	118	2	106	2.0e-09	54.9	COG2963	Transposase and inactivated derivatives	116
646769150	341	30.03	39	326	9	294	2.0e-38	152	COG0583	DNA-binding transcriptional regulator, LysR family	297
646769151	249	38.98	3	247	2	251	2.0e-41	162	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
646769152	317	30.38	5	290	2	291	5.0e-30	125	COG0583	DNA-binding transcriptional regulator, LysR family	297
646769153	1832	35.26	294	1110	2	823	0.0e+00	482	COG3899	Predicted ATPase	849
646769154	494	59.71	3	477	15	490	0.0e+00	700	COG0753	Catalase	496
646769155	298	32.44	3	294	2	296	8.0e-36	144	COG0583	DNA-binding transcriptional regulator, LysR family	297
646769156	139	25.53	44	136	39	131	2.0e-06	44.8	COG1917	Cupin domain protein related to quercetin dioxygenase	131
646769159	268	30	77	185	8	117	1.0e-13	70.8	COG2863	Cytochrome c553	121
646769160	544	25.75	4	483	16	492	1.0e-53	204	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
646769163	448	19.59	299	446	11	147	2.0e-09	57.3	COG2010	Cytochrome c, mono- and diheme variants	150
646769164	199	34.07	3	93	34	118	1.0e-12	66.6	COG2863	Cytochrome c553	121
646769165	273	20.85	59	267	1	201	3.0e-15	75.6	COG1335	Nicotinamidase-related amidase	205
646769167	345	32.54	33	323	6	294	5.0e-39	155	COG0583	DNA-binding transcriptional regulator, LysR family	297
646769168	507	34.55	18	506	3	455	3.0e-97	349	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
646769170	247	33.07	4	245	2	251	1.0e-30	127	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
646769171	220	42.64	11	207	1	197	8.0e-59	220	COG4566	Two-component response regulator, FixJ family, consists of REC and HTH domains	202
646769173	190	40.35	15	185	9	171	1.0e-35	142	COG1881	Uncharacterized conserved protein, phosphatidylethanolamine-binding protein (PEBP) family	174
646769174	332	25.35	42	321	48	292	4.0e-20	92.3	COG3781	Predicted membrane chloride channel, bestrophin family	306
646769175	278	27.34	1	277	1	280	3.0e-26	112	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
646769177	251	24.91	1	250	1	265	3.0e-19	88.8	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
646769180	399	40.22	203	380	2	179	2.0e-36	146	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
646769181	230	35.91	17	195	4	183	4.0e-31	128	COG3658	Cytochrome b	192
646769183	402	40.68	211	385	4	179	2.0e-37	150	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
646769184	620	52.91	1	617	8	575	0.0e+00	773	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
646769185	381	37.05	22	373	2	357	8.0e-61	227	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
646769186	143	28.91	1	127	4	129	1.0e-13	69.3	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
646769187	224	33.02	1	214	1	208	8.0e-27	113	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
646769189	326	29.23	1	323	1	309	6.0e-37	148	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
646769191	207	41.82	5	159	4	168	1.0e-38	152	COG0350	O6-methylguanine-DNA--protein-cysteine methyltransferase	168
646769193	418	23	40	410	33	407	2.0e-26	113	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
646769194	342	33.64	230	337	17	124	3.0e-14	73	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
646769196	521	34.89	136	517	2	408	2.0e-42	167	COG0840	Methyl-accepting chemotaxis protein	408
646769197	179	26.23	29	149	4	125	2.0e-13	68.8	COG1846	DNA-binding transcriptional regulator, MarR family	126
646769198	395	19.25	18	395	5	354	3.0e-21	96.6	COG3203	Outer membrane protein (porin)	354
646769199	324	31.51	28	324	9	313	5.0e-37	148	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
646769200	470	23.77	5	325	1	318	4.0e-11	63.3	COG2814	Predicted arabinose efflux permease, MFS family	394
646769201	326	33.57	28	307	37	311	1.0e-53	203	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
646769205	362	22.95	9	356	6	350	1.0e-29	124	COG3203	Outer membrane protein (porin)	354
646769211	390	30.91	1	377	1	365	9.0e-63	234	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
646769212	446	19.39	37	443	38	445	5.0e-10	59.4	COG2271	Sugar phosphate permease	448
646769214	352	24.77	2	311	22	327	1.0e-33	137	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
646769215	281	19.93	2	279	10	276	2.0e-17	83	COG3618	Predicted metal-dependent hydrolase, TIM-barrel fold	279
646769216	367	28.53	1	365	1	350	3.0e-44	172	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
646769217	264	24.56	1	262	8	277	8.0e-25	107	COG3618	Predicted metal-dependent hydrolase, TIM-barrel fold	279
646769218	417	23.24	22	291	23	304	5.0e-23	102	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
646769220	394	18.7	8	386	14	392	3.0e-22	99.9	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
646769221	380	20.49	72	325	62	320	1.0e-07	51.6	COG4447	Uncharacterized protein related to plant photosystem II stability/assembly factor	339
646769222	319	31.82	6	254	3	262	3.0e-43	168	COG1018	Ferredoxin-NADP reductase	266
646769223	337	25.89	1	332	7	291	5.0e-22	98.6	COG2159	Predicted metal-dependent hydrolase, TIM-barrel fold	293
646769225	220	34.12	1	211	4	204	5.0e-28	118	COG0684	Regulator of RNase E activity RraA	210
646769226	225	36.71	1	207	3	202	2.0e-36	145	COG0684	Regulator of RNase E activity RraA	210
646769227	223	37.86	15	220	5	204	2.0e-41	162	COG0684	Regulator of RNase E activity RraA	210
646769228	181	34.38	1	158	2	159	1.0e-28	119	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
646769229	233	34.97	26	207	20	201	3.0e-26	112	COG1802	DNA-binding transcriptional regulator, GntR family	230
646769230	235	42.39	5	235	1	236	8.0e-47	180	COG0412	Dienelactone hydrolase	236
646769231	395	21.55	61	378	6	347	6.0e-21	95.4	COG3203	Outer membrane protein (porin)	354
646769232	528	22.58	13	300	1	309	2.0e-13	71.4	COG2814	Predicted arabinose efflux permease, MFS family	394
646769233	265	21.71	13	264	44	298	4.0e-12	65.5	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
646769234	804	28.53	135	437	77	382	4.0e-44	173	COG1472	Periplasmic beta-glucosidase and related glycosidases	397
646769235	449	28.88	12	418	1	371	9.0e-57	214	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
646769236	443	20.79	11	426	15	435	1.0e-19	91	COG2271	Sugar phosphate permease	448
646769237	236	37.83	3	228	10	234	4.0e-35	141	COG2186	DNA-binding transcriptional regulator, FadR family	241
646769239	742	71.43	1	742	2	743	0.0e+00	1205	COG2838	Monomeric isocitrate dehydrogenase	744
646769240	457	23.26	17	435	15	436	2.0e-30	127	COG2271	Sugar phosphate permease	448
646769241	353	39.82	5	331	1	333	5.0e-74	271	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
646769242	294	29.64	25	292	6	281	2.0e-29	123	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
646769243	420	23.63	46	409	37	388	2.0e-16	81	COG2814	Predicted arabinose efflux permease, MFS family	394
646769244	343	26.04	3	330	1	337	1.0e-57	217	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
646769245	316	77.07	3	316	2	309	8.0e-126	443	COG4569	Acetaldehyde dehydrogenase (acetylating)	310
646769246	268	43.87	1	268	1	262	5.0e-62	230	COG3971	2-keto-4-pentenoate hydratase	264
646769248	617	26.49	18	395	2	382	6.0e-53	202	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
646769249	279	25.79	8	258	1	244	3.0e-25	108	COG1414	DNA-binding transcriptional regulator, IclR family	246
646769251	346	25.96	6	313	1	300	6.0e-34	138	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
646769252	461	34.42	155	461	33	333	3.0e-42	166	COG0642	Signal transduction histidine kinase	336
646769253	225	41.3	1	222	1	229	2.0e-49	189	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
646769254	339	26.49	1	298	3	296	3.0e-32	133	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
646769255	264	51.38	9	260	1	244	1.0e-84	305	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
646769256	287	34.9	32	286	7	257	8.0e-47	180	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
646769260	516	27.82	8	350	43	417	1.0e-30	128	COG3511	Phospholipase C	527
646769263	403	25.1	68	330	16	238	4.0e-22	99.3	COG1562	Phytoene/squalene synthetase	288
646769264	511	24.22	267	509	4	256	1.0e-21	98.6	COG0467	RecA-superfamily ATPase, KaiC/GvpD/RAD55 family	260
646769266	341	30.36	8	305	9	311	3.0e-32	133	COG1275	Tellurite resistance protein TehA and related permeases	329
646769267	163	58.6	3	159	2	151	1.0e-31	129	COG3918	Uncharacterized membrane protein	153
646769268	292	29.59	5	287	1	292	1.0e-34	140	COG0583	DNA-binding transcriptional regulator, LysR family	297
646769272	256	42.04	7	240	6	250	6.0e-50	190	COG0631	Serine/threonine protein phosphatase PrpC	262
646769274	1022	43.04	308	1018	1	708	0.0e+00	701	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
646769275	250	19.85	1	249	34	296	1.0e-06	47	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
646769276	457	20.98	35	396	19	289	1.0e-08	55	COG1566	Multidrug resistance efflux pump	352
646769278	470	32.97	15	468	1	456	2.0e-57	216	COG1538	Outer membrane protein TolC	457
646769282	678	31.75	402	678	2	314	6.0e-42	166	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
646769283	717	28.42	123	393	2	282	2.0e-39	158	COG0515	Serine/threonine protein kinase	384
646769287	266	40.54	5	257	3	251	2.0e-47	182	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
646769289	209	38.39	1	209	1	207	6.0e-25	107	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
646769290	157	45.27	4	151	2	148	1.0e-32	132	COG1522	DNA-binding transcriptional regulator, Lrp family	154
646769291	262	22.78	37	256	21	277	6.0e-10	58.2	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
646769294	347	24.4	55	343	3	277	4.0e-20	92.5	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
646769295	238	29.86	3	216	9	219	5.0e-15	74.9	COG0785	Cytochrome c biogenesis protein CcdA	220
646769296	179	21.08	28	174	1	155	1.0e-06	46.4	COG1225	Peroxiredoxin	157
646769298	440	26.04	42	440	27	406	2.0e-51	197	COG1228	Imidazolonepropionase or related amidohydrolase	406
646769299	738	34.25	77	391	47	365	3.0e-50	194	COG1472	Periplasmic beta-glucosidase and related glycosidases	397
646769300	392	32.24	107	350	36	277	1.0e-30	127	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
646769301	195	35.24	7	105	2	106	2.0e-08	52.7	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
646769303	151	30.83	16	134	5	124	5.0e-06	44.2	COG1846	DNA-binding transcriptional regulator, MarR family	126
646769305	213	41.41	6	202	5	202	6.0e-42	164	COG2860	Uncharacterized membrane protein YeiH	209
646769306	322	31.47	64	310	65	314	3.0e-19	89.5	COG2064	Pilus assembly protein TadC	320
646769307	325	33.12	9	325	5	309	5.0e-50	191	COG4965	Flp pilus assembly protein TadB	309
646769308	453	53.61	51	410	1	355	5.0e-115	408	COG4962	Pilus assembly protein, ATPase of CpaF family	355
646769309	403	26.33	3	396	1	364	2.0e-43	170	COG4963	Flp pilus assembly protein, ATPase CpaE	366
646769311	634	38.19	104	546	35	448	2.0e-81	297	COG4964	Flp pilus assembly protein, secretin CpaC	455
646769312	276	41.27	1	236	1	251	7.0e-46	177	COG3745	Flp pilus assembly protein CpaB	276
646769313	180	34.13	13	179	10	162	8.0e-12	63.7	COG4960	Flp pilus assembly protein, protease CpaA	168
646769314	56	53.57	1	56	1	53	3.0e-08	49.9	COG3847	Flp pilus assembly protein, pilin Flp	58
646769315	56	52.08	9	56	6	53	2.0e-08	50.6	COG3847	Flp pilus assembly protein, pilin Flp	58
646769318	353	27.46	7	285	2	277	8.0e-21	94.8	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
646769321	411	26.09	13	402	1	382	6.0e-12	65.6	COG2814	Predicted arabinose efflux permease, MFS family	394
646769322	287	40.81	5	275	4	274	5.0e-56	211	COG1737	DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains	281
646769323	360	53.95	1	354	1	338	4.0e-127	448	COG3839	ABC-type sugar transport system, ATPase component	338
646769324	261	34.33	2	233	6	232	1.0e-35	143	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
646769325	410	28.9	1	408	2	430	3.0e-43	169	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
646769326	296	37.88	1	293	1	292	4.0e-61	228	COG1175	ABC-type sugar transport system, permease component	295
646769327	283	38.95	1	283	2	281	7.0e-57	214	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
646769328	97	36.08	1	96	1	96	2.0e-12	64.5	COG5470	Uncharacterized conserved protein, DUF1330 family	96
646769329	343	27.65	22	302	1	272	2.0e-18	87.1	COG0388	Predicted amidohydrolase	274
646769330	298	29.8	1	294	1	297	1.0e-25	110	COG0583	DNA-binding transcriptional regulator, LysR family	297
646769336	313	28.12	1	309	7	319	2.0e-37	149	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
646769337	342	47.9	33	340	13	312	1.0e-60	227	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
646769338	505	55.44	1	495	5	498	0.0e+00	644	COG1129	ABC-type sugar transport system, ATPase component	500
646769339	253	34.7	36	252	13	230	2.0e-29	122	COG1802	DNA-binding transcriptional regulator, GntR family	230
646769340	431	27.44	2	427	1	372	5.0e-59	222	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
646769341	303	29.87	8	301	1	295	2.0e-31	130	COG0583	DNA-binding transcriptional regulator, LysR family	297
646769342	157	30.41	8	155	1	129	1.0e-13	69.5	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
646769343	398	33.07	24	397	24	403	3.0e-63	236	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
646769344	339	46.83	11	339	3	323	1.0e-77	283	COG2515	1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase, PLP-dependent ACC family	323
646769347	241	25.91	22	230	13	259	1.0e-11	63.8	COG3336	Cytochrome c oxidase assembly factor CtaG	299
646769349	170	30.82	25	165	7	152	1.0e-15	76.4	COG4244	Uncharacterized membrane protein	160
646769350	228	35.53	3	223	2	226	1.0e-39	156	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
646769351	845	46.06	34	538	11	517	0.0e+00	466	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
646769353	256	37.4	4	255	3	251	6.0e-59	221	COG4700	Uncharacterized protein	251
646769355	451	21.08	79	429	63	384	6.0e-10	59.1	COG2814	Predicted arabinose efflux permease, MFS family	394
646769357	257	44.92	21	253	6	238	2.0e-74	272	COG3473	Maleate cis-trans isomerase	238
646769358	219	40.09	3	218	6	222	7.0e-51	193	COG0765	ABC-type amino acid transport system, permease component	222
646769359	219	40.09	1	211	8	219	3.0e-47	181	COG0765	ABC-type amino acid transport system, permease component	222
646769360	280	29.43	2	260	1	262	3.0e-27	115	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
646769361	300	56.35	43	294	1	240	7.0e-101	360	COG1126	ABC-type polar amino acid transport system, ATPase component	240
646769362	406	32.4	16	406	1	384	7.0e-83	301	COG0006	Xaa-Pro aminopeptidase	384
646769363	363	37.15	6	353	1	326	6.0e-62	231	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
646769367	465	42.45	5	458	3	448	0.0e+00	517	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
646769368	507	45.22	13	481	3	467	3.0e-128	452	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
646769369	163	40.27	1	149	4	151	4.0e-27	114	COG1522	DNA-binding transcriptional regulator, Lrp family	154
646769370	341	43.58	1	335	1	330	1.0e-85	309	COG3608	Predicted deacylase	331
646769371	334	42.25	1	327	1	327	8.0e-72	264	COG2423	Ornithine cyclodeaminase/archaeal alanine dehydrogenase, mu-crystallin family	330
646769372	343	43.08	9	329	7	327	1.0e-81	296	COG1171	Threonine dehydratase	347
646769373	465	26.97	18	461	5	459	3.0e-79	289	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
646769375	178	31.64	1	173	3	179	3.0e-19	88.4	COG2059	Chromate transport protein ChrA	195
646769376	207	28.96	26	205	1	183	2.0e-21	96.1	COG2059	Chromate transport protein ChrA	195
646769377	537	35.34	29	490	1	449	2.0e-56	214	COG1538	Outer membrane protein TolC	457
646769378	1102	33.33	2	1076	1	1009	0.0e+00	809	COG0841	Multidrug efflux pump subunit AcrB	1009
646769379	1046	37.39	2	1017	1	1008	0.0e+00	894	COG0841	Multidrug efflux pump subunit AcrB	1009
646769380	430	31.81	10	376	2	366	8.0e-27	115	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
646769383	374	21.54	42	364	14	328	6.0e-22	98.7	COG0642	Signal transduction histidine kinase	336
646769386	135	51.49	1	134	1	134	2.0e-35	141	COG4954	Uncharacterized protein	135
646769389	198	23.65	15	198	1	203	7.0e-15	74.1	COG1335	Nicotinamidase-related amidase	205
646769390	331	32.82	4	325	2	314	3.0e-59	222	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
646769393	413	38.39	5	412	7	426	1.0e-114	406	COG2873	O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent	426
646769394	122	36.11	7	103	15	122	5.0e-13	66.6	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
646769395	303	22.07	52	267	25	245	3.0e-20	92.8	COG5607	CHAD domain (function unknown)	283
646769399	702	34.35	16	364	12	359	2.0e-45	178	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
646769403	264	30.04	19	264	2	251	6.0e-35	141	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
646769406	305	34.62	201	304	23	126	4.0e-20	92.2	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
646769407	845	21.11	178	845	2	600	2.0e-11	65.2	COG3468	Type V secretory pathway, adhesin AidA	644
646769411	304	30.82	17	294	1	292	1.0e-27	117	COG0583	DNA-binding transcriptional regulator, LysR family	297
646769412	336	38.77	17	336	4	326	3.0e-58	219	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
646769413	162	21.17	26	153	22	158	1.0e-06	46.5	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
646769415	338	34.44	70	336	48	311	1.0e-37	150	COG0657	Acetyl esterase/lipase	312
646769416	476	31.05	121	469	1	339	5.0e-31	129	COG3903	Predicted ATPase	414
646769418	231	31.46	7	218	15	213	7.0e-19	87.6	COG3619	Uncharacterized membrane protein YoaK, UPF0700 family	226
646769420	148	32.11	25	132	18	122	1.0e-07	49.2	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
646769421	629	44.2	4	542	1	535	0.0e+00	507	COG1574	Predicted amidohydrolase YtcJ	535
646769423	228	14.49	9	206	1	205	3.0e-23	102	COG1335	Nicotinamidase-related amidase	205
646769424	93	48.91	1	92	1	92	3.0e-19	86.5	COG4317	Xanthosine utilization system component, XapX domain	93
646769426	526	32.26	1	421	2	422	4.0e-51	196	COG0025	NhaP-type Na+/H+ or K+/H+ antiporter	429
646769427	294	36.69	2	276	5	276	8.0e-55	207	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
646769428	568	33.85	242	562	2	304	4.0e-58	219	COG0492	Thioredoxin reductase	305
646769429	300	32.77	4	294	2	292	9.0e-36	144	COG0583	DNA-binding transcriptional regulator, LysR family	297
646769430	849	39.14	148	562	7	409	2.0e-56	214	COG3903	Predicted ATPase	414
646769431	160	31.21	7	160	4	154	4.0e-26	110	COG3837	Uncharacterized conserved protein, cupin superfamily	161
646769433	305	31.89	5	300	1	295	1.0e-35	143	COG0583	DNA-binding transcriptional regulator, LysR family	297
646769434	254	40.55	4	251	2	250	3.0e-42	165	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
646769435	235	27.11	11	230	13	237	1.0e-27	116	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
646769436	138	23.7	7	138	33	158	6.0e-06	43.4	COG4454	Uncharacterized copper-binding protein, cupredoxin-like subfamily	158
646769438	238	30.34	75	236	42	217	3.0e-23	101	COG4122	Predicted O-methyltransferase YrrM	219
646769441	193	28.09	8	185	8	176	1.0e-17	83.2	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
646769442	245	21.53	11	215	46	247	3.0e-14	72	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
646769445	405	29.02	5	375	2	367	8.0e-42	164	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
646769446	314	24.5	6	302	1	295	1.0e-27	117	COG0583	DNA-binding transcriptional regulator, LysR family	297
646769447	334	23.55	59	317	36	292	6.0e-09	55.3	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
646769448	355	28.45	1	205	13	244	3.0e-23	102	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
646769449	218	39.02	1	199	1	193	2.0e-61	228	COG0450	Alkyl hydroperoxide reductase subunit AhpC (peroxiredoxin)	194
646769450	299	55.48	1	291	1	291	2.0e-111	395	COG1210	UTP-glucose-1-phosphate uridylyltransferase	291
646769452	752	73.47	5	752	16	730	0.0e+00	1180	COG0376	Catalase (peroxidase I)	730
646769454	628	41.79	11	542	5	532	0.0e+00	482	COG1574	Predicted amidohydrolase YtcJ	535
646769455	211	16.94	6	180	1	182	3.0e-19	88.7	COG1335	Nicotinamidase-related amidase	205
646769456	954	35.82	141	540	17	405	2.0e-42	168	COG3903	Predicted ATPase	414
646769457	302	39	202	301	23	122	8.0e-22	98	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
646769458	501	34.68	154	492	16	348	3.0e-33	136	COG3903	Predicted ATPase	414
646769460	223	45.96	18	215	4	201	3.0e-56	211	COG4566	Two-component response regulator, FixJ family, consists of REC and HTH domains	202
646769461	1843	33.06	306	1150	2	849	2.0e-123	438	COG3899	Predicted ATPase	849
646769462	347	24.04	99	306	21	209	4.0e-12	66	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
646769464	274	30.99	1	274	1	282	2.0e-25	110	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
646769467	248	24.55	25	247	14	226	8.0e-15	74.5	COG3619	Uncharacterized membrane protein YoaK, UPF0700 family	226
646769470	141	32.26	9	126	11	133	4.0e-06	44.2	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
646769471	211	16.94	6	180	1	182	3.0e-19	88.7	COG1335	Nicotinamidase-related amidase	205
646769472	335	31.21	68	335	6	281	4.0e-30	125	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
646769473	305	31.8	4	304	3	295	9.0e-34	137	COG0583	DNA-binding transcriptional regulator, LysR family	297
646769474	404	27.18	21	397	14	387	2.0e-21	97.2	COG2814	Predicted arabinose efflux permease, MFS family	394
646769475	198	42.79	1	198	1	201	7.0e-57	213	COG1182	FMN-dependent NADH-azoreductase	202
646769478	206	41.5	12	206	19	216	8.0e-40	157	COG4117	Thiosulfate reductase cytochrome b subunit	221
646769479	264	34.02	32	261	2	241	2.0e-49	189	COG2041	Periplasmic DMSO/TMAO reductase YedYZ, molybdopterin-dependent catalytic subunit	271
646769481	794	41.04	406	747	2	336	1.0e-98	354	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
646769482	257	42.08	7	254	2	249	3.0e-41	161	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
646769483	184	32.2	54	171	4	120	1.0e-12	66.5	COG1846	DNA-binding transcriptional regulator, MarR family	126
646769484	283	33.72	21	280	3	257	8.0e-46	177	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
646769485	403	41.94	21	397	5	392	2.0e-65	243	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
646769486	146	25	1	136	2	135	1.0e-21	96.1	COG0824	Acyl-CoA thioesterase FadM	137
646769487	131	34.65	7	131	10	130	7.0e-19	86.1	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
646769488	546	31.92	34	543	5	517	3.0e-109	389	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
646769489	407	33.62	12	233	10	236	2.0e-43	170	COG0412	Dienelactone hydrolase	236
646769492	277	40	127	276	2	155	5.0e-36	145	COG3708	Predicted transcriptional regulator YdeE, contains AraC-type DNA-binding domain	157
646769494	290	38.96	136	289	1	153	1.0e-38	153	COG3449	DNA gyrase inhibitor GyrI	154
646769496	165	22	5	150	14	162	5.0e-08	50.8	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
646769497	193	27.01	12	184	10	176	1.0e-23	103	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
646769499	530	39.03	26	495	2	459	4.0e-102	365	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
646769500	244	27.03	31	208	2	186	1.0e-18	86.6	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
646769502	505	36.55	53	498	14	457	2.0e-55	210	COG1538	Outer membrane protein TolC	457
646769503	383	25.65	10	367	1	368	2.0e-26	113	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
646769504	1022	40.28	1	1004	1	1008	0.0e+00	847	COG0841	Multidrug efflux pump subunit AcrB	1009
646769505	322	37.76	1	321	1	326	2.0e-50	193	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
646769507	205	25.73	2	205	1	206	7.0e-18	84.2	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
646769508	424	55.48	5	424	2	413	2.0e-116	413	COG4941	Predicted RNA polymerase sigma factor, contains C-terminal TPR domain	415
646769509	137	45.16	1	122	1	120	8.0e-29	119	COG3795	Uncharacterized conserved protein	123
646769510	117	29.09	1	110	1	110	7.0e-19	86.1	COG3795	Uncharacterized conserved protein	123
646769514	120	40.19	8	114	3	107	9.0e-25	105	COG3805	Aromatic ring-cleaving dioxygenase	120
646769516	229	24.23	6	228	3	205	7.0e-17	80.8	COG0778	Nitroreductase	207
646769517	240	29.17	23	238	8	209	3.0e-26	112	COG3295	Uncharacterized protein	213
646769518	227	59.39	1	227	3	229	1.0e-80	292	COG3128	Predicted 2-oxoglutarate- and Fe(II)-dependent dioxygenase YbiX	229
646769519	738	33.33	35	738	31	750	1.0e-119	424	COG4774	Outer membrane receptor for monomeric catechols	750
646769520	331	47.26	1	321	1	308	1.0e-78	287	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
646769521	188	38.2	14	188	2	173	4.0e-32	131	COG1881	Uncharacterized conserved protein, phosphatidylethanolamine-binding protein (PEBP) family	174
646769524	274	24.09	20	251	7	306	3.0e-19	89.5	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
646769525	539	47	37	528	1	481	0.0e+00	554	COG0364	Glucose-6-phosphate 1-dehydrogenase	483
646769527	656	26.05	12	648	2	608	2.0e-68	254	COG3408	Glycogen debranching enzyme (alpha-1,6-glucosidase)	641
646769528	305	34.68	6	300	4	297	2.0e-68	252	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
646769529	371	24.86	14	365	33	331	6.0e-28	118	COG3608	Predicted deacylase	331
646769530	255	29.02	7	255	17	270	3.0e-38	152	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
646769531	306	27.54	3	306	1	297	7.0e-28	118	COG0583	DNA-binding transcriptional regulator, LysR family	297
646769532	422	37.8	2	397	7	394	3.0e-90	325	COG0019	Diaminopimelate decarboxylase	394
646769533	312	32.11	3	297	1	295	2.0e-27	116	COG0583	DNA-binding transcriptional regulator, LysR family	297
646769534	284	30.08	10	260	10	251	8.0e-41	160	COG0300	Short-chain dehydrogenase	265
646769535	144	52.83	91	143	1	53	3.0e-16	77.6	COG1773	Rubredoxin	55
646769536	396	25.79	44	349	28	336	3.0e-33	136	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
646769537	483	24.93	76	420	37	375	3.0e-30	126	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
646769538	199	40.54	17	199	5	178	4.0e-31	128	COG3038	Cytochrome b561	181
646769539	229	21.89	9	209	3	201	5.0e-10	58.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
646769540	214	30.73	1	196	1	203	3.0e-24	105	COG0625	Glutathione S-transferase	211
646769541	432	22.77	21	423	1	394	3.0e-16	79.9	COG2814	Predicted arabinose efflux permease, MFS family	394
646769543	239	29.25	1	237	1	251	6.0e-26	111	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
646769544	316	24.75	12	306	1	292	3.0e-26	112	COG0583	DNA-binding transcriptional regulator, LysR family	297
646769547	310	27.52	4	299	1	292	3.0e-25	109	COG0583	DNA-binding transcriptional regulator, LysR family	297
646769548	429	21	15	422	21	433	9.0e-25	108	COG2271	Sugar phosphate permease	448
646769549	511	43.29	1	490	1	477	2.0e-121	429	COG5476	Microcystin degradation protein MlrC, contains DUF1485 domain	488
646769552	436	21.04	23	431	21	412	2.0e-17	84.1	COG2223	Nitrate/nitrite transporter NarK	417
646769553	364	47.19	1	355	1	347	9.0e-124	436	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
646769554	308	30.69	9	303	5	294	2.0e-34	140	COG0583	DNA-binding transcriptional regulator, LysR family	297
646769556	432	26.2	6	312	1	320	4.0e-25	109	COG2358	TRAP-type uncharacterized transport system, periplasmic component	321
646769560	570	29.04	71	569	42	523	3.0e-79	289	COG3511	Phospholipase C	527
646769562	249	30.48	38	232	54	259	8.0e-34	137	COG1864	DNA/RNA endonuclease G, NUC1	281
646769564	410	26.21	122	410	91	365	5.0e-24	105	COG2208	Serine phosphatase RsbU, regulator of sigma subunit	367
646769567	241	38.76	69	239	4	181	3.0e-34	138	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
646769571	179	49.43	1	173	1	174	1.0e-45	175	COG4539	Uncharacterized membrane protein YGL010W	180
646769572	298	36.99	4	294	3	290	2.0e-54	206	COG2962	Uncharacterized membrane protein RarD, contains two EamA domains	293
646769573	327	43.87	16	323	15	318	2.0e-65	242	COG4301	Uncharacterized conserved protein, contains predicted SAM-dependent methyltransferase domain	321
646769574	97	46.07	7	95	1	89	7.0e-23	98.8	COG1254	Acylphosphatase	92
646769575	336	26.95	9	329	3	309	7.0e-35	141	COG0451	Nucleoside-diphosphate-sugar epimerase	314
646769577	390	19.32	2	390	12	437	4.0e-14	73	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
646769578	288	31.7	8	271	23	285	1.0e-32	133	COG1562	Phytoene/squalene synthetase	288
646769579	314	60.07	1	292	2	294	1.0e-110	393	COG0761	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH	294
646769580	384	27.27	21	310	12	317	6.0e-25	108	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
646769581	200	30.77	5	196	10	202	1.0e-31	129	COG2854	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic MlaC component	202
646769582	871	18.64	16	865	12	787	5.0e-20	93.9	COG4258	Predicted exporter	788
646769583	339	44.8	1	241	2	250	9.0e-63	234	COG2853	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, lipoprotein component MlaA	250
646769584	174	35.88	18	145	16	145	3.0e-25	108	COG1607	Acyl-CoA hydrolase	157
646769588	694	30.31	144	685	1	516	2.0e-66	247	COG1657	Squalene cyclase	517
646769589	422	20.83	7	381	8	404	2.0e-12	67.4	COG1233	Phytoene dehydrogenase-related protein	487
646769590	282	33.45	9	282	9	285	1.0e-36	147	COG1562	Phytoene/squalene synthetase	288
646769591	316	45.6	131	311	1	181	4.0e-44	171	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
646769592	207	25.87	6	202	7	201	9.0e-13	67.3	COG1776	Chemotaxis protein CheY-P-specific phosphatase CheC	203
646769595	764	23.08	338	605	77	335	2.0e-24	107	COG0642	Signal transduction histidine kinase	336
646769597	185	40.57	4	171	2	172	2.0e-35	141	COG0431	NAD(P)H-dependent FMN reductase	184
646769600	202	28.65	15	192	21	179	3.0e-18	85.1	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
646769602	96	59.7	1	67	1	67	2.0e-18	83.9	COG3813	Uncharacterized protein	84
646769603	327	26.84	18	321	7	319	6.0e-39	154	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
646769604	119	35.29	1	119	2	116	8.0e-26	109	COG1393	Arsenate reductase and related proteins, glutaredoxin family	117
646769605	220	27.13	2	220	1	255	4.0e-24	104	COG1192	Cellulose biosynthesis protein BcsQ	259
646769606	351	24.31	84	301	2	211	1.0e-13	71.5	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
646769609	360	23.28	58	306	36	271	3.0e-07	49.8	COG4974	Site-specific recombinase XerD	300
646769611	215	30.11	38	129	2	94	3.0e-08	52.3	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
646769612	401	50.26	5	393	3	388	1.0e-120	426	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
646769613	343	35.13	1	340	1	350	5.0e-76	278	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
646769614	216	39.18	42	211	20	190	1.0e-33	136	COG2353	Polyisoprenoid-binding periplasmic protein YceI	192
646769615	223	23.56	7	197	1	186	3.0e-07	48.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
646769616	159	77.12	7	159	2	154	3.0e-66	243	COG3558	Uncharacterized conserved protein, nuclear transport factor 2 (NTF2) superfamily	154
646769618	435	20.5	84	435	67	406	8.0e-07	48.7	COG2223	Nitrate/nitrite transporter NarK	417
646769619	477	19.85	10	403	19	409	3.0e-16	80.2	COG2271	Sugar phosphate permease	448
646769620	322	32.47	1	260	1	265	2.0e-42	166	COG1018	Ferredoxin-NADP reductase	266
646769621	306	27.12	8	301	2	292	2.0e-26	113	COG0583	DNA-binding transcriptional regulator, LysR family	297
646769622	427	29.59	22	385	4	334	1.0e-43	171	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
646769623	166	24.14	13	152	6	150	1.0e-10	59.2	COG5517	3-phenylpropionate/cinnamic acid dioxygenase, small subunit	164
646769624	63	31.58	1	56	1	57	9.0e-07	45.3	COG1942	Phenylpyruvate tautomerase PptA, 4-oxalocrotonate tautomerase family	69
646769626	389	19.53	9	365	8	372	3.0e-23	103	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
646769629	380	35.31	21	374	79	465	4.0e-71	262	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
646769630	247	36.9	1	244	3	250	9.0e-32	130	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
646769631	218	47	10	209	1	200	4.0e-61	227	COG4566	Two-component response regulator, FixJ family, consists of REC and HTH domains	202
646769632	178	31.65	17	171	7	162	2.0e-28	118	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
646769633	548	27.66	33	449	1	412	1.0e-59	224	COG1914	Mn2+ and Fe2+ transporters of the NRAMP family	416
646769637	252	28.69	8	244	7	247	1.0e-19	90.3	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
646769638	320	37.03	4	319	13	324	1.0e-67	249	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
646769640	329	32.56	10	308	1	297	4.0e-28	118	COG0583	DNA-binding transcriptional regulator, LysR family	297
646769641	397	40.4	1	396	4	396	2.0e-111	395	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
646769642	321	27.67	15	312	1	289	3.0e-46	179	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
646769643	443	20.59	24	443	24	448	9.0e-21	95.3	COG2271	Sugar phosphate permease	448
646769644	249	39.37	8	227	1	220	1.0e-35	143	COG1802	DNA-binding transcriptional regulator, GntR family	230
646769645	406	41.67	14	394	8	382	3.0e-97	349	COG0075	Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism protein PucG	383
646769646	428	21.85	13	409	30	439	2.0e-23	104	COG2271	Sugar phosphate permease	448
646769647	249	22.96	3	247	8	260	1.0e-12	67.2	COG3971	2-keto-4-pentenoate hydratase	264
646769648	1010	30.29	30	538	2	458	2.0e-64	241	COG0277	FAD/FMN-containing dehydrogenase	459
646769649	311	41	204	303	23	122	7.0e-22	98	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
646769650	298	24.22	26	280	37	276	2.0e-07	49.9	COG5006	Threonine/homoserine efflux transporter RhtA	292
646769653	199	22.17	3	198	2	204	8.0e-09	53.7	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
646769654	576	33.23	249	566	3	302	4.0e-52	199	COG0492	Thioredoxin reductase	305
646769655	330	28.21	7	198	13	203	3.0e-24	106	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
646769657	466	20.48	4	460	6	438	2.0e-59	223	COG2610	H+/gluconate symporter or related permease	442
646769658	488	40.21	12	487	108	560	1.0e-126	447	COG3829	Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding Fis domains	560
646769661	399	31.4	29	390	55	376	4.0e-39	155	COG1680	CubicO group peptidase, beta-lactamase class C family	390
646769662	99	30.43	1	97	13	127	8.0e-11	58.9	COG2916	DNA-binding protein H-NS	128
646769663	533	59.27	3	524	6	528	0.0e+00	765	COG4108	Peptide chain release factor RF-3	528
646769664	821	34.99	4	443	2	462	1.0e-68	254	COG1042	Acyl-CoA synthetase (NDP forming)	598
646769666	261	29.63	14	254	1	241	7.0e-39	154	COG1414	DNA-binding transcriptional regulator, IclR family	246
646769667	346	29.29	11	339	2	312	2.0e-52	199	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
646769668	276	32.85	1	276	8	278	2.0e-48	186	COG3618	Predicted metal-dependent hydrolase, TIM-barrel fold	279
646769669	247	38.55	4	246	2	251	6.0e-38	151	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
646769670	282	43.88	10	282	1	266	6.0e-75	274	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
646769671	144	33.33	3	135	6	138	4.0e-18	83.9	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
646769672	540	37.47	159	512	30	408	1.0e-43	171	COG0840	Methyl-accepting chemotaxis protein	408
646769673	67	65.67	1	67	1	67	3.0e-25	106	COG1278	Cold shock protein, CspA family	67
646769674	377	29.18	14	363	8	375	5.0e-46	178	COG2942	Mannose or cellobiose epimerase, N-acyl-D-glucosamine 2-epimerase family	388
646769679	314	39.8	16	311	6	300	2.0e-65	243	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
646769680	203	30.81	12	196	4	175	1.0e-27	116	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
646769681	477	46.49	6	416	3	415	3.0e-126	445	COG4553	Poly-beta-hydroxyalkanoate depolymerase	415
646769682	217	25	6	209	1	211	3.0e-21	95.7	COG0625	Glutathione S-transferase	211
646769683	657	36.64	315	652	49	408	9.0e-49	188	COG0840	Methyl-accepting chemotaxis protein	408
646769684	880	48.95	111	870	3	712	0.0e+00	696	COG2217	Cation transport ATPase	713
646769685	215	53.85	1	195	1	193	4.0e-65	241	COG2808	Predicted FMN-binding regulatory protein PaiB	209
646769686	472	28.3	19	472	9	457	1.0e-43	171	COG5361	Uncharacterized conserved protein	458
646769690	904	57.4	7	903	4	861	0.0e+00	1135	COG1048	Aconitase A	861
646769691	483	46.85	7	481	1	453	0.0e+00	464	COG2079	2-methylcitrate dehydratase PrpD	453
646769693	395	47.77	21	394	13	390	3.0e-122	431	COG0372	Citrate synthase	390
646769694	338	24.83	27	320	7	283	1.0e-31	130	COG2301	Citrate lyase beta subunit	283
646769695	327	33.64	6	326	1	311	1.0e-67	250	COG0039	Malate/lactate dehydrogenase	313
646769696	266	43.75	29	265	2	236	1.0e-50	193	COG2188	DNA-binding transcriptional regulator, GntR family	236
646769697	138	33.61	21	138	9	130	5.0e-11	60.3	COG2009	Succinate dehydrogenase/fumarate reductase, cytochrome b subunit	132
646769698	122	34.48	7	122	1	116	4.0e-18	83.7	COG2142	Succinate dehydrogenase, hydrophobic anchor subunit	117
646769699	591	50.87	8	577	2	562	0.0e+00	610	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
646769700	234	55.56	3	234	2	232	3.0e-82	297	COG0479	Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit	234
646769701	90	38.82	5	89	7	91	6.0e-15	72.6	COG2938	Succinate dehydrogenase flavin-adding protein, antitoxin component of the CptAB toxin-antitoxin module	94
646769702	433	53.09	30	433	1	390	0.0e+00	500	COG0372	Citrate synthase	390
646769703	469	57.2	1	468	1	422	0.0e+00	617	COG0065	Homoaconitase/3-isopropylmalate dehydratase large subunit	423
646769705	217	56.13	1	212	1	190	2.0e-78	284	COG0066	3-isopropylmalate dehydratase small subunit	191
646769706	355	53.04	1	355	4	345	8.0e-122	430	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
646769707	373	31.37	1	371	2	334	2.0e-92	332	COG0136	Aspartate-semialdehyde dehydrogenase	334
646769709	270	51.17	1	256	1	256	7.0e-89	320	COG0101	tRNA U38,U39,U40 pseudouridine synthase TruA	266
646769710	243	41.12	29	240	1	208	7.0e-52	197	COG0135	Phosphoribosylanthranilate isomerase	208
646769711	397	71.83	3	396	1	393	0.0e+00	711	COG0133	Tryptophan synthase beta chain	396
646769712	304	24.81	22	279	1	264	1.0e-34	140	COG0863	DNA modification methylase	302
646769713	270	46.42	1	265	1	265	3.0e-84	305	COG0159	Tryptophan synthase alpha chain	265
646769714	290	59.31	1	290	1	290	7.0e-121	426	COG0777	Acetyl-CoA carboxylase beta subunit	294
646769715	436	44.27	1	433	1	423	8.0e-121	427	COG0285	Folylpolyglutamate synthase/Dihydropteroate synthase	427
646769716	322	27.95	62	315	8	220	2.0e-12	66.6	COG3147	Cell division protein DedD (periplasmic protein involved in septation)	226
646769717	183	29.55	2	176	1	175	6.0e-20	90.7	COG1286	Uncharacterized membrane protein, required for colicin V production	182
646769718	516	52.66	1	483	4	468	0.0e+00	604	COG0034	Glutamine phosphoribosylpyrophosphate amidotransferase	470
646769719	262	38	160	259	21	120	1.0e-19	90.7	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
646769722	447	34.16	1	440	1	422	8.0e-90	324	COG1253	Hemolysin or related protein, contains CBS domains	429
646769723	955	45.17	1	950	1	889	0.0e+00	878	COG3280	Maltooligosyltrehalose synthase	889
646769724	732	34.29	166	720	6	520	3.0e-117	416	COG1640	4-alpha-glucanotransferase	520
646769725	634	32.68	12	533	19	560	2.0e-121	430	COG0296	1,4-alpha-glucan branching enzyme	628
646769726	737	49.36	11	698	14	693	0.0e+00	785	COG1523	Pullulanase/glycogen debranching enzyme	697
646769727	736	56.54	101	735	1	628	0.0e+00	739	COG0296	1,4-alpha-glucan branching enzyme	628
646769728	1155	35.56	46	550	1	505	1.0e-94	341	COG0366	Glycosidase	505
646769730	220	30.52	13	219	20	228	1.0e-41	163	COG4291	Uncharacterized membrane protein	228
646769732	533	24.6	1	533	2	537	2.0e-70	260	COG2303	Choline dehydrogenase or related flavoprotein	542
646769738	283	34.78	4	268	1	274	1.0e-21	97	COG0583	DNA-binding transcriptional regulator, LysR family	297
646769740	120	32.35	2	103	1	100	5.0e-11	59.8	COG0640	DNA-binding transcriptional regulator, ArsR family	110
646769741	164	33.33	1	142	1	139	4.0e-28	117	COG0394	Protein-tyrosine-phosphatase	139
646769742	355	43.7	17	355	9	339	5.0e-78	284	COG0798	Arsenite efflux pump ArsB, ACR3 family	342
646769744	416	19.56	39	398	38	388	5.0e-06	46	COG2814	Predicted arabinose efflux permease, MFS family	394
646769746	281	43.51	13	143	1	130	6.0e-29	121	COG2005	DNA-binding transcriptional regulator ModE (molybdenum-dependent)	130
646769748	224	55.81	1	214	2	216	1.0e-58	220	COG4149	ABC-type molybdate transport system, permease component	225
646769749	295	40.08	45	294	7	257	2.0e-54	206	COG0725	ABC-type molybdate transport system, periplasmic component	258
646769751	392	31.39	74	376	21	310	5.0e-38	152	COG3509	Poly(3-hydroxybutyrate) depolymerase	312
646769753	152	38.96	1	150	5	158	1.0e-23	102	COG3476	Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)	161
646769754	499	42.92	15	497	5	457	1.0e-124	440	COG0415	Deoxyribodipyrimidine photolyase	461
646769755	139	48.57	1	139	4	143	1.0e-39	155	COG1764	Organic hydroperoxide reductase OsmC/OhrA	143
646769756	150	48.45	24	120	5	101	2.0e-12	65.7	COG1846	DNA-binding transcriptional regulator, MarR family	126
646769758	331	32.41	1	317	5	317	5.0e-58	218	COG2334	Ser/Thr protein kinase RdoA involved in Cpx stress response, MazF antagonist	331
646769760	509	21.69	219	487	1	233	3.0e-40	159	COG0775	Nucleoside phosphorylase	234
646769762	247	40.8	34	231	1	201	2.0e-45	176	COG1611	Predicted Rossmann fold nucleotide-binding protein	205
646769763	913	56.91	315	913	2	593	0.0e+00	781	COG0749	DNA polymerase I - 3'-5' exonuclease and polymerase domains	593
646769764	451	35.52	1	440	3	405	1.0e-95	343	COG1252	NADH dehydrogenase, FAD-containing subunit	405
646769765	290	38.06	49	290	1	236	2.0e-49	189	COG0412	Dienelactone hydrolase	236
646769766	289	40.57	9	288	12	285	5.0e-67	247	COG2897	3-mercaptopyruvate sulfurtransferase SseA, contains two rhodanese domains	285
646769767	368	23.2	14	365	2	356	4.0e-43	168	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
646769768	102	42.42	24	89	10	75	1.0e-08	51.5	COG1722	Exonuclease VII small subunit	81
646769769	293	36.14	1	293	1	322	5.0e-61	227	COG0142	Geranylgeranyl pyrophosphate synthase	322
646769770	650	62.6	16	638	1	626	0.0e+00	956	COG1154	Deoxyxylulose-5-phosphate synthase	627
646769771	268	43.77	11	266	6	285	2.0e-67	249	COG1469	GTP cyclohydrolase FolE2	289
646769772	342	53.37	1	340	1	337	5.0e-121	427	COG0533	tRNA A37 threonylcarbamoyltransferase TsaD	342
646769773	417	47.1	13	415	1	408	1.0e-129	456	COG2081	Predicted flavoprotein YhiN	408
646769774	70	59.38	1	64	1	64	7.0e-07	45.6	COG0828	Ribosomal protein S21	67
646769775	148	56.08	1	147	1	148	7.0e-37	146	COG1610	Uncharacterized conserved protein YqeY	148
646769776	624	34.76	1	599	1	568	3.0e-123	436	COG0358	DNA primase (bacterial type)	568
646769777	680	46.24	322	678	1	342	8.0e-90	324	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
646769780	380	25.65	1	380	1	354	6.0e-45	175	COG3203	Outer membrane protein (porin)	354
646769782	246	19.9	32	234	7	212	9.0e-21	94.1	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
646769783	544	33.33	10	544	1	531	2.0e-110	393	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
646769784	212	29.13	5	208	4	208	4.0e-20	91.5	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
646769785	88	22.11	2	87	32	126	8.0e-07	45.4	COG2916	DNA-binding protein H-NS	128
646769786	195	37.44	2	194	25	225	3.0e-29	121	COG3485	Protocatechuate 3,4-dioxygenase beta subunit	226
646769787	234	46.7	9	234	10	225	1.0e-52	199	COG3485	Protocatechuate 3,4-dioxygenase beta subunit	226
646769788	340	32.56	12	311	3	297	1.0e-34	140	COG0583	DNA-binding transcriptional regulator, LysR family	297
646769789	375	44.59	7	373	3	350	8.0e-90	324	COG3185	4-hydroxyphenylpyruvate dioxygenase and related hemolysins	363
646769790	310	30.74	7	298	1	296	5.0e-37	148	COG0583	DNA-binding transcriptional regulator, LysR family	297
646769792	995	29.49	48	549	9	456	5.0e-58	220	COG0277	FAD/FMN-containing dehydrogenase	459
646769793	211	24.74	15	110	1	97	2.0e-07	49.6	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
646769794	273	37.35	6	252	4	255	3.0e-50	192	COG2513	2-Methylisocitrate lyase and related enzymes, PEP mutase family	289
646769797	364	35.21	10	360	1	307	2.0e-52	200	COG2017	Galactose mutarotase or related enzyme	308
646769798	406	27.11	3	279	51	321	3.0e-26	113	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
646769799	440	68.81	1	436	3	438	0.0e+00	698	COG2115	Xylose isomerase	438
646769800	342	56.46	16	339	6	338	3.0e-106	378	COG4213	ABC-type xylose transport system, periplasmic component	341
646769801	519	52.47	1	505	4	499	0.0e+00	607	COG1129	ABC-type sugar transport system, ATPase component	500
646769802	399	55.47	25	394	16	390	3.0e-112	398	COG4214	ABC-type xylose transport system, permease component	394
646769803	756	24.83	45	755	35	722	4.0e-77	283	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
646769804	153	45.03	4	152	6	156	1.0e-44	171	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
646769805	522	32.74	41	484	4	447	4.0e-50	193	COG1538	Outer membrane protein TolC	457
646769806	336	36.09	2	290	8	342	6.0e-56	211	COG1566	Multidrug resistance efflux pump	352
646769808	700	24.64	3	700	5	674	1.0e-56	215	COG1289	Uncharacterized membrane protein YccC	674
646769809	206	31.25	23	134	8	118	4.0e-10	58.4	COG1846	DNA-binding transcriptional regulator, MarR family	126
646769811	504	35.14	9	262	2	260	1.0e-42	167	COG0467	RecA-superfamily ATPase, KaiC/GvpD/RAD55 family	260
646769813	206	32.34	1	192	1	186	7.0e-20	90.7	COG0406	Broad specificity phosphatase PhoE	208
646769821	341	25.86	51	339	32	320	2.0e-49	189	COG0598	Mg2+ and Co2+ transporter CorA	322
646769822	393	55.63	1	151	1	150	4.0e-58	218	COG1017	Hemoglobin-like flavoprotein	150
646769823	531	47.18	27	531	34	546	0.0e+00	501	COG3604	Transcriptional regulator containing GAF, AAA-type ATPase, and DNA-binding Fis domains	550
646769824	280	45.96	4	275	2	269	2.0e-75	275	COG3777	Hydroxyacyl-ACP dehydratase HTD2, hotdog domain	273
646769825	387	37.34	1	387	1	393	2.0e-82	299	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
646769826	392	47.21	1	392	5	396	5.0e-113	401	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
646769827	462	30.89	3	445	4	445	1.0e-68	254	COG2079	2-methylcitrate dehydratase PrpD	453
646769828	272	41.61	7	266	1	272	4.0e-52	198	COG2301	Citrate lyase beta subunit	283
646769829	539	41.79	1	537	18	549	7.0e-120	424	COG3507	Beta-xylosidase	549
646769830	432	26.21	3	401	24	428	9.0e-37	148	COG2271	Sugar phosphate permease	448
646769831	304	33.11	12	304	6	294	7.0e-35	141	COG0583	DNA-binding transcriptional regulator, LysR family	297
646769833	460	20.19	18	431	9	384	9.0e-13	68.7	COG2814	Predicted arabinose efflux permease, MFS family	394
646769834	303	30.33	3	300	1	296	2.0e-36	146	COG0583	DNA-binding transcriptional regulator, LysR family	297
646769835	499	36.42	16	487	11	472	2.0e-109	389	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
646769836	390	26.48	1	373	3	377	3.0e-44	172	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
646769837	402	42.78	24	400	87	458	2.0e-89	322	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
646769838	367	26.87	11	339	17	335	2.0e-29	123	COG4269	Uncharacterized membrane protein YjgN, DUF898 family	364
646769839	665	44.81	330	664	10	342	4.0e-85	309	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
646769846	496	34.4	1	494	1	486	3.0e-85	309	COG5476	Microcystin degradation protein MlrC, contains DUF1485 domain	488
646769848	567	49.24	1	328	1	321	5.0e-82	298	COG2376	Dihydroxyacetone kinase	323
646769850	351	22.82	66	346	15	312	1.0e-25	110	COG0701	Uncharacterized membrane protein YraQ, UPF0718 family	317
646769851	355	30.67	13	326	14	322	2.0e-28	120	COG2603	tRNA 2-selenouridine synthase SelU, contains rhodanese domain	334
646769852	352	51.15	6	352	2	346	2.0e-103	369	COG0709	Selenophosphate synthase	346
646769856	307	42.18	28	238	10	202	3.0e-55	209	COG0437	Fe-S-cluster-containing dehydrogenase component	203
646769857	218	56.1	13	215	2	205	6.0e-56	210	COG2864	Cytochrome b subunit of formate dehydrogenase	218
646769858	332	37.3	1	317	1	305	3.0e-60	225	COG3058	Formate dehydrogenase maturation protein FdhE	308
646769859	482	58.14	89	475	18	392	3.0e-105	376	COG1921	Seryl-tRNA(Sec) selenium transferase	395
646769860	637	37.87	1	470	1	447	1.0e-100	360	COG3276	Selenocysteine-specific translation elongation factor	447
646769861	387	20.7	92	346	1	250	1.0e-05	44.6	COG0582	Integrase	309
646769863	448	18.66	18	425	21	432	3.0e-25	110	COG2271	Sugar phosphate permease	448
646769864	538	35.02	79	537	12	474	2.0e-90	327	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
646769865	291	40.28	14	290	1	283	1.0e-44	173	COG2301	Citrate lyase beta subunit	283
646769866	398	44.08	4	398	2	396	2.0e-109	389	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
646769867	284	44.04	7	282	2	272	1.0e-67	250	COG3777	Hydroxyacyl-ACP dehydratase HTD2, hotdog domain	273
646769868	310	54.11	1	310	1	310	2.0e-79	289	COG2025	Electron transfer flavoprotein, alpha subunit	313
646769869	249	50.38	1	249	1	260	4.0e-67	247	COG2086	Electron transfer flavoprotein, alpha and beta subunits	260
646769870	390	39.8	6	390	3	393	8.0e-86	310	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
646769871	309	32.89	1	299	1	297	6.0e-34	138	COG0583	DNA-binding transcriptional regulator, LysR family	297
646769872	367	22.31	1	367	1	354	9.0e-38	151	COG3203	Outer membrane protein (porin)	354
646769873	449	20.32	26	431	36	438	2.0e-09	57.5	COG2271	Sugar phosphate permease	448
646769874	334	29.03	209	331	1	124	8.0e-14	71.4	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
646769876	498	35.71	1	497	1	478	7.0e-94	338	COG5476	Microcystin degradation protein MlrC, contains DUF1485 domain	488
646769877	889	56.88	19	887	7	884	0.0e+00	1124	COG2609	Pyruvate dehydrogenase complex, dehydrogenase (E1) component	887
646769880	370	35.83	2	358	1	339	9.0e-75	274	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
646769885	335	40	1	335	3	346	2.0e-62	233	COG1294	Cytochrome bd-type quinol oxidase, subunit 2	346
646769886	462	44.79	4	448	2	452	2.0e-129	456	COG1271	Cytochrome bd-type quinol oxidase, subunit 1	457
646769887	757	24.3	1	756	1	765	3.0e-99	356	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
646769888	386	38.54	67	362	20	316	9.0e-74	270	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
646769889	1857	30.07	319	1162	2	849	2.0e-110	394	COG3899	Predicted ATPase	849
646769890	218	50.75	10	207	4	202	3.0e-57	215	COG4566	Two-component response regulator, FixJ family, consists of REC and HTH domains	202
646769891	299	30.81	2	211	6	205	4.0e-28	118	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
646769892	432	19.1	75	425	63	393	5.0e-07	49.4	COG2814	Predicted arabinose efflux permease, MFS family	394
646769894	335	38.56	1	318	1	316	1.0e-71	263	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
646769895	377	47.13	12	359	6	339	2.0e-94	339	COG3376	High-affinity nickel permease	342
646769898	218	51.74	10	210	1	201	3.0e-61	228	COG4566	Two-component response regulator, FixJ family, consists of REC and HTH domains	202
646769899	245	41.3	6	245	6	251	1.0e-41	163	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
646769900	313	33.06	193	313	5	125	2.0e-20	93.4	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
646769902	272	31.23	1	271	2	280	2.0e-26	112	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
646769904	351	35.23	55	350	21	312	2.0e-52	199	COG0657	Acetyl esterase/lipase	312
646769905	158	73.03	6	157	2	153	1.0e-63	235	COG3558	Uncharacterized conserved protein, nuclear transport factor 2 (NTF2) superfamily	154
646769906	342	40.77	84	341	59	312	6.0e-51	194	COG0657	Acetyl esterase/lipase	312
646769909	362	34.47	10	313	26	343	4.0e-65	242	COG2837	Periplasmic deferrochelatase/peroxidase EfeB	352
646769910	266	56.18	1	265	1	267	5.0e-72	264	COG1659	Uncharacterized protein, linocin/CFP29 family	267
646769912	225	48.7	1	223	1	229	5.0e-60	224	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
646769913	471	30.79	136	471	2	330	2.0e-35	144	COG0642	Signal transduction histidine kinase	336
646769914	492	38.22	41	475	13	448	1.0e-53	204	COG1538	Outer membrane protein TolC	457
646769915	406	30	36	401	10	372	1.0e-23	104	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
646769916	1071	29.43	2	1039	1	1003	0.0e+00	655	COG0841	Multidrug efflux pump subunit AcrB	1009
646769921	192	31.49	13	192	5	184	3.0e-24	105	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
646769922	214	28.48	39	202	1	157	3.0e-10	58.5	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
646769925	190	25	79	182	10	113	2.0e-08	52.5	COG1917	Cupin domain protein related to quercetin dioxygenase	131
646769926	918	14.96	27	918	2	768	8.0e-21	96.5	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
646769927	239	28.09	74	239	65	242	3.0e-08	52.5	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
646769928	302	33.97	79	282	1	209	3.0e-35	142	COG0811	Biopolymer transport protein ExbB/TolQ	216
646769929	141	33.58	3	139	1	137	8.0e-28	116	COG0848	Biopolymer transport protein ExbD	137
646769930	143	34.13	15	140	11	135	9.0e-22	96.1	COG0848	Biopolymer transport protein ExbD	137
646769932	629	25.08	22	621	10	559	2.0e-69	257	COG4166	ABC-type oligopeptide transport system, periplasmic component	562
646769933	351	54.67	1	350	1	364	0.0e+00	486	COG4174	ABC-type microcin C transport system, permease component YejB	364
646769934	351	58.38	8	341	6	338	4.0e-119	421	COG4239	ABC-type microcin C transport system, permease component YejE	341
646769935	547	59.37	7	536	5	532	0.0e+00	688	COG4172	ABC-type microcin C transport system, duplicated ATPase component YejF	534
646769936	478	27.51	12	477	12	454	2.0e-66	246	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
646769937	453	19.38	20	446	3	451	1.0e-31	131	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
646769938	179	26.9	11	170	8	178	6.0e-14	70.8	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
646769939	194	26.44	18	180	10	183	1.0e-15	76.5	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
646769940	1061	48.59	4	1026	5	1008	0.0e+00	922	COG0841	Multidrug efflux pump subunit AcrB	1009
646769942	230	30.14	16	219	2	207	3.0e-23	102	COG3571	Predicted hydrolase of the alpha/beta-hydrolase fold	213
646769943	134	32.84	1	134	1	132	7.0e-17	79.6	COG3631	Ketosteroid isomerase-related protein	133
646769944	178	49.4	3	167	2	167	1.0e-44	172	COG3516	Predicted component of the type VI protein secretion system	169
646769945	502	52.39	1	502	1	495	0.0e+00	636	COG3517	Predicted component of the type VI protein secretion system	495
646769946	163	27.63	10	156	15	160	9.0e-19	86.5	COG3157	Type VI protein secretion system component Hcp (secreted cytotoxin)	162
646769947	145	36.36	11	138	14	145	4.0e-12	64.2	COG3518	Predicted component of the type VI protein secretion system	157
646769948	585	37.52	2	585	1	621	3.0e-121	429	COG3519	Type VI protein secretion system component VasA	621
646769949	364	35.55	4	344	1	325	4.0e-46	178	COG3520	Predicted component of the type VI protein secretion system	335
646769950	910	40.02	11	880	1	762	0.0e+00	747	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
646769951	640	36.23	2	537	4	549	3.0e-126	445	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
646769955	328	23.71	90	312	27	248	8.0e-17	81.6	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
646769956	424	29.66	14	418	10	395	1.0e-40	160	COG1301	Na+/H+-dicarboxylate symporter	415
646769957	233	29.82	1	224	1	227	4.0e-41	161	COG1794	Aspartate/glutamate racemase	230
646769958	474	23.76	14	435	12	413	2.0e-25	110	COG1301	Na+/H+-dicarboxylate symporter	415
646769960	444	26.85	7	355	1	354	9.0e-36	145	COG3522	Predicted component of the type VI protein secretion system	446
646769963	380	25.62	25	380	10	345	3.0e-18	86.7	COG3515	Predicted component of the type VI protein secretion system	346
646769965	321	25.83	149	261	23	139	8.0e-12	65	COG0590	tRNA(Arg) A34 adenosine deaminase TadA	152
646769968	190	35.29	2	185	5	187	2.0e-29	121	COG3963	Phospholipid N-methyltransferase	194
646769969	649	27.69	1	322	2	293	7.0e-28	119	COG0501	Zn-dependent protease with chaperone function	302
646769970	199	46.63	5	196	1	185	6.0e-52	197	COG1704	Uncharacterized conserved protein	185
646769974	280	31.13	39	247	1	212	2.0e-24	106	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
646769976	621	25.31	12	399	12	399	3.0e-26	113	COG4252	Extracellular (periplasmic) sensor domain CHASE2 (specificity unknown)	400
646769979	806	23.93	83	394	57	381	2.0e-19	92	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
646769980	343	23.92	1	339	1	370	4.0e-24	105	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
646769981	441	17.82	212	404	7	206	1.0e-05	44.8	COG0500	SAM-dependent methyltransferase	257
646769982	417	43.15	10	253	2	249	5.0e-80	291	COG1134	ABC-type polysaccharide/polyol phosphate transport system, ATPase component	249
646769983	260	25.77	1	260	10	263	5.0e-29	121	COG1682	ABC-type polysaccharide/polyol phosphate export permease	263
646769984	402	25.84	26	402	16	379	4.0e-31	129	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
646769985	612	54.78	1	573	3	577	0.0e+00	709	COG4618	ABC-type protease/lipase transport system, ATPase and permease components	580
646769986	454	21.23	19	374	4	277	5.0e-13	69.6	COG1566	Multidrug resistance efflux pump	352
646769987	488	27.49	48	468	45	457	1.0e-42	168	COG1538	Outer membrane protein TolC	457
646769991	408	21.75	1	394	5	366	1.0e-08	54.4	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
646769996	222	24.41	1	209	1	213	1.0e-17	83.4	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
646769997	309	37.94	1	279	1	278	6.0e-56	211	COG1273	Non-homologous end joining protein Ku, dsDNA break repair	278
646769999	324	29.47	3	299	2	296	5.0e-34	138	COG0583	DNA-binding transcriptional regulator, LysR family	297
646770001	381	41.55	9	381	1	351	2.0e-101	363	COG1304	FMN-dependent dehydrogenase, includes L-lactate dehydrogenase and type II isopentenyl diphosphate isomerase	360
646770002	150	36.67	1	141	5	154	5.0e-15	73.9	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
646770005	317	34.42	1	306	14	316	1.0e-40	160	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
646770006	334	20.9	1	332	3	322	7.0e-20	91.8	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
646770008	336	24.04	58	256	8	204	8.0e-18	84.7	COG0412	Dienelactone hydrolase	236
646770010	766	25.62	68	755	35	720	9.0e-65	242	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
646770011	160	52.35	1	148	3	151	3.0e-50	191	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
646770013	529	29.83	7	526	4	541	2.0e-66	247	COG2985	Uncharacterized membrane protein YbjL, putative transporter	544
646770014	596	38.5	1	396	1	388	1.0e-72	267	COG1263	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific	393
646770015	847	48.94	295	845	5	569	0.0e+00	629	COG1080	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria)	574
646770016	412	37.92	20	400	10	394	3.0e-52	199	COG2814	Predicted arabinose efflux permease, MFS family	394
646770017	112	45.1	1	101	1	97	6.0e-24	102	COG4321	Predicted DNA-binding protein, contains Ribbon-helix-helix (RHH) domain	102
646770018	192	35.15	1	192	1	188	1.0e-26	112	COG0693	Putative intracellular protease/amidase	188
646770019	161	31.4	35	154	3	123	5.0e-13	67.3	COG1846	DNA-binding transcriptional regulator, MarR family	126
646770020	409	23.1	41	408	37	393	1.0e-17	84.9	COG2814	Predicted arabinose efflux permease, MFS family	394
646770021	294	34.58	1	290	11	290	2.0e-57	216	COG2159	Predicted metal-dependent hydrolase, TIM-barrel fold	293
646770022	169	31.19	53	161	14	122	2.0e-10	59.2	COG1846	DNA-binding transcriptional regulator, MarR family	126
646770023	275	32.17	8	264	5	254	2.0e-48	186	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
646770024	483	46.01	6	479	3	472	5.0e-122	431	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
646770025	626	25.79	44	565	8	514	5.0e-56	212	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
646770026	594	33.33	37	461	6	388	1.0e-61	231	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
646770027	250	28.27	20	250	13	246	2.0e-24	106	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
646770028	271	54.81	3	241	31	269	4.0e-83	301	COG2326	Polyphosphate kinase 2, PPK2 family	270
646770030	195	29.07	30	194	14	185	2.0e-24	105	COG2930	Lipid-binding SYLF domain	227
646770032	207	54.31	8	201	7	202	5.0e-57	213	COG4566	Two-component response regulator, FixJ family, consists of REC and HTH domains	202
646770035	416	29.11	12	378	2	358	5.0e-32	132	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
646770036	1077	46.23	2	1031	1	1007	0.0e+00	973	COG0841	Multidrug efflux pump subunit AcrB	1009
646770037	504	37.86	15	469	1	451	3.0e-69	256	COG1538	Outer membrane protein TolC	457
646770038	426	35.89	5	422	17	413	7.0e-79	288	COG2995	Uncharacterized paraquat-inducible protein A	418
646770039	537	35.93	1	537	1	546	9.0e-120	424	COG3008	Paraquat-inducible protein B	553
646770040	207	19.58	20	205	4	190	1.0e-10	60	COG3009	Uncharacterized lipoprotein YmbA	190
646770042	311	28.57	29	304	23	327	1.0e-49	190	COG0280	Phosphotransacetylase	327
646770043	391	45.09	3	390	1	393	3.0e-122	431	COG0282	Acetate kinase	396
646770044	260	48.62	8	260	2	254	6.0e-83	300	COG0623	Enoyl-[acyl-carrier-protein] reductase (NADH)	259
646770051	583	31.46	20	570	3	547	1.0e-94	341	COG0659	Sulfate permease or related transporter, MFS superfamily	554
646770054	577	26.87	63	577	158	772	1.0e-71	264	COG4993	Glucose dehydrogenase	773
646770055	206	47	17	115	7	102	6.0e-20	90.8	COG2863	Cytochrome c553	121
646770056	220	31.31	7	196	17	211	3.0e-13	68.8	COG0666	Ankyrin repeat	235
646770057	230	40.09	9	224	6	220	1.0e-35	142	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
646770058	275	26.64	1	214	2	201	5.0e-24	105	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
646770059	140	38.69	1	137	1	135	2.0e-27	114	COG0848	Biopolymer transport protein ExbD	137
646770060	256	34.39	9	228	1	216	8.0e-40	157	COG0811	Biopolymer transport protein ExbB/TolQ	216
646770061	263	24.69	19	261	10	243	1.0e-10	60.2	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
646770062	371	26.55	33	360	1	302	5.0e-20	92.6	COG3391	DNA-binding beta-propeller fold protein YncE	381
646770065	316	35.11	35	294	12	263	2.0e-33	136	COG3336	Cytochrome c oxidase assembly factor CtaG	299
646770066	453	27.15	167	315	16	150	4.0e-07	50	COG2010	Cytochrome c, mono- and diheme variants	150
646770067	250	36.18	22	244	10	255	1.0e-31	130	COG3568	Metal-dependent hydrolase, endonuclease/exonuclease/phosphatase family	259
646770068	773	24.11	33	417	59	406	7.0e-32	132	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
646770070	1056	20.89	298	846	1	609	1.0e-29	126	COG3899	Predicted ATPase	849
646770076	330	34.55	4	330	3	330	4.0e-77	281	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
646770077	339	28.4	1	319	4	322	2.0e-33	136	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
646770078	302	35.53	7	302	1	304	5.0e-61	227	COG3386	Sugar lactone lactonase YvrE	307
646770079	328	34.29	19	328	4	312	5.0e-37	148	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
646770080	321	30.65	17	321	6	315	3.0e-34	139	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
646770081	493	35.81	6	490	1	500	8.0e-121	427	COG1129	ABC-type sugar transport system, ATPase component	500
646770082	344	27.96	1	325	2	322	7.0e-33	134	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
646770083	486	42.14	1	485	4	499	9.0e-117	414	COG1070	Sugar (pentulose or hexulose) kinase	502
646770084	297	36.59	166	288	5	127	1.0e-21	97.6	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
646770085	389	50	1	356	1	336	7.0e-118	417	COG3839	ABC-type sugar transport system, ATPase component	338
646770086	344	33.71	1	343	1	350	1.0e-63	237	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
646770087	270	33.21	1	267	5	275	2.0e-39	156	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
646770088	292	31.06	1	292	3	292	2.0e-44	172	COG1175	ABC-type sugar transport system, permease component	295
646770089	423	23.72	1	419	5	431	3.0e-31	129	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
646770093	255	38.43	5	243	4	240	3.0e-41	162	COG2186	DNA-binding transcriptional regulator, FadR family	241
646770094	456	18.05	32	443	21	436	8.0e-20	92.2	COG2271	Sugar phosphate permease	448
646770095	579	18.03	21	568	1	459	2.0e-36	147	COG0277	FAD/FMN-containing dehydrogenase	459
646770096	313	23.43	9	311	2	288	3.0e-11	62.6	COG1276	Putative copper export protein	289
646770097	123	32.5	5	123	7	125	1.0e-16	78.9	COG2372	Copper-binding protein CopC (methionine-rich)	127
646770098	116	46.9	2	114	1	107	1.0e-15	75.5	COG5569	Periplasmic Cu and Ag efflux protein CusF	108
646770099	431	26.55	72	408	33	360	2.0e-33	137	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
646770100	501	22.22	74	462	46	457	4.0e-29	122	COG1538	Outer membrane protein TolC	457
646770104	828	55.5	13	828	4	773	0.0e+00	909	COG4993	Glucose dehydrogenase	773
646770106	465	46.31	4	444	2	448	0.0e+00	469	COG1271	Cytochrome bd-type quinol oxidase, subunit 1	457
646770107	336	40.17	1	336	2	346	2.0e-65	243	COG1294	Cytochrome bd-type quinol oxidase, subunit 2	346
646770108	198	35.07	1	198	2	211	9.0e-34	136	COG2085	Predicted dinucleotide-binding enzyme	211
646770109	255	42.97	4	253	2	250	6.0e-42	164	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
646770110	245	37.85	4	243	2	251	2.0e-38	152	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
646770111	305	28.24	6	303	2	297	5.0e-27	115	COG0583	DNA-binding transcriptional regulator, LysR family	297
646770112	485	26.27	31	479	10	447	2.0e-63	237	COG2079	2-methylcitrate dehydratase PrpD	453
646770113	348	32.13	14	335	25	340	4.0e-42	165	COG0673	Predicted dehydrogenase	342
646770114	323	30.71	18	265	2	254	9.0e-43	167	COG0169	Shikimate 5-dehydrogenase	283
646770116	249	34.43	46	249	1	211	1.0e-29	123	COG0625	Glutathione S-transferase	211
646770117	208	21	4	200	2	201	1.0e-08	53.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
646770118	257	39.69	4	256	2	251	1.0e-39	156	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
646770119	463	30.28	15	454	1	455	6.0e-75	274	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
646770121	339	25.58	5	301	1	274	1.0e-32	134	COG0388	Predicted amidohydrolase	274
646770122	376	20.29	25	373	1	336	1.0e-42	167	COG2516	Biotin synthase-related protein, radical SAM superfamily	339
646770124	328	36.59	1	314	1	311	3.0e-66	245	COG2144	Selenophosphate synthetase-related protein	324
646770125	389	23.86	6	386	3	380	2.0e-25	110	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
646770127	433	24.64	15	420	6	413	7.0e-42	165	COG2072	Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD	443
646770129	698	51.15	7	523	26	544	0.0e+00	576	COG1884	Methylmalonyl-CoA mutase, N-terminal domain/subunit	548
646770131	357	33.02	8	327	17	321	9.0e-55	207	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
646770135	324	22.81	41	317	6	281	2.0e-19	90.1	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
646770136	394	42.79	4	392	2	390	1.0e-72	267	COG0183	Acetyl-CoA acetyltransferase	392
646770137	283	39.78	100	283	4	189	1.0e-38	153	COG3703	Cation transport regulator ChaC	190
646770138	303	33	3	297	2	294	1.0e-36	147	COG0583	DNA-binding transcriptional regulator, LysR family	297
646770140	271	31.67	19	255	1	240	2.0e-33	136	COG1414	DNA-binding transcriptional regulator, IclR family	246
646770141	531	30.78	7	524	17	552	3.0e-82	299	COG0747	ABC-type transport system, periplasmic component	556
646770142	341	47.17	20	337	2	313	3.0e-81	295	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
646770143	287	43.17	10	285	11	288	3.0e-60	225	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
646770144	339	54.17	6	316	1	307	2.0e-113	402	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
646770145	331	46.69	2	309	1	316	3.0e-95	342	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
646770146	385	32.14	50	378	17	334	3.0e-43	169	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
646770147	407	21.17	24	402	20	392	2.0e-26	113	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
646770148	554	37.14	132	235	6	109	2.0e-09	57.6	COG0607	Rhodanese-related sulfurtransferase	110
646770149	451	31.19	34	416	14	336	1.0e-40	161	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
646770150	277	44.26	32	275	13	256	1.0e-49	190	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
646770151	245	46.41	18	240	5	241	5.0e-64	237	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
646770152	349	24.13	3	340	1	329	1.0e-16	81	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
646770154	560	34.26	145	251	3	109	5.0e-10	59.9	COG0607	Rhodanese-related sulfurtransferase	110
646770156	327	37.85	16	298	5	286	8.0e-59	220	COG2175	Taurine dioxygenase, alpha-ketoglutarate-dependent	286
646770157	443	22.82	4	438	1	432	2.0e-26	113	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
646770158	303	38.3	15	295	8	286	2.0e-53	203	COG1175	ABC-type sugar transport system, permease component	295
646770159	309	38.79	36	308	1	281	2.0e-56	213	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
646770160	356	54.44	1	349	1	337	1.0e-123	436	COG3839	ABC-type sugar transport system, ATPase component	338
646770165	105	58.33	1	96	1	96	1.0e-31	127	COG0234	Co-chaperonin GroES (HSP10)	96
646770166	540	48.09	1	533	1	523	0.0e+00	477	COG0459	Chaperonin GroEL (HSP60 family)	524
646770168	187	32.14	48	187	7	146	4.0e-21	94.7	COG0071	Molecular chaperone IbpA, HSP20 family	146
646770169	135	32.5	17	133	27	146	2.0e-15	75	COG0071	Molecular chaperone IbpA, HSP20 family	146
646770170	146	31.11	11	145	12	143	7.0e-21	93.1	COG0071	Molecular chaperone IbpA, HSP20 family	146
646770174	260	48.21	1	250	3	252	1.0e-80	293	COG1124	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	252
646770175	292	48.33	9	275	1	268	1.0e-87	316	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
646770176	304	53.65	29	301	12	285	4.0e-74	271	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
646770177	356	43.03	27	356	5	314	7.0e-80	290	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
646770178	535	28.47	1	535	4	554	8.0e-62	231	COG0747	ABC-type transport system, periplasmic component	556
646770179	187	44.57	4	175	31	205	3.0e-36	144	COG2173	D-alanyl-D-alanine dipeptidase	211
646770180	301	32.19	7	296	1	267	7.0e-39	154	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
646770181	304	37.93	16	302	3	282	9.0e-49	187	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
646770182	431	19.43	18	363	3	318	1.0e-24	107	COG0687	Spermidine/putrescine-binding periplasmic protein	363
646770183	352	44.1	11	352	1	352	2.0e-96	346	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
646770185	251	31.75	23	231	20	229	2.0e-32	132	COG1802	DNA-binding transcriptional regulator, GntR family	230
646770186	196	30.22	13	194	7	176	1.0e-28	120	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
646770187	528	38.52	7	526	12	537	5.0e-125	441	COG0405	Gamma-glutamyltranspeptidase	539
646770189	478	24.94	25	422	4	336	5.0e-43	169	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
646770190	413	21.55	18	400	20	393	2.0e-33	136	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
646770191	499	41.41	1	480	4	478	2.0e-123	436	COG1129	ABC-type sugar transport system, ATPase component	500
646770192	352	42.86	25	351	3	316	3.0e-49	189	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
646770193	411	25.76	26	407	14	393	4.0e-47	182	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
646770194	356	23.4	9	330	1	319	2.0e-22	99.8	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
646770195	80	43.37	1	79	1	83	1.0e-09	54.7	COG3609	Transcriptional regulator, contains Arc/MetJ-type RHH (ribbon-helix-helix) DNA-binding domain	89
646770196	99	34.38	1	96	1	96	1.0e-14	71.2	COG3668	Plasmid stabilization system protein ParE	98
646770197	132	26.92	1	128	1	126	4.0e-17	80.4	COG5455	Periplasmic regulator RcnB of Ni and Co efflux	129
646770199	343	27.54	12	341	20	352	1.0e-23	104	COG0628	Predicted PurR-regulated permease PerM	355
646770200	223	30.21	21	209	11	202	1.0e-20	93.4	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
646770204	355	54.34	8	353	14	347	4.0e-114	404	COG5042	Purine nucleoside permease	349
646770205	337	43.65	5	325	1	308	1.0e-78	287	COG2826	Transposase and inactivated derivatives, IS30 family	318
646770209	306	29.53	1	296	1	294	2.0e-33	136	COG0583	DNA-binding transcriptional regulator, LysR family	297
646770211	458	19.36	77	441	79	433	9.0e-09	55.2	COG2271	Sugar phosphate permease	448
646770212	573	30.42	1	566	5	542	2.0e-69	257	COG2303	Choline dehydrogenase or related flavoprotein	542
646770213	268	36.76	20	265	7	257	7.0e-44	171	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
646770214	524	35.51	1	504	10	523	3.0e-97	349	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
646770215	178	56.21	17	168	4	156	4.0e-49	187	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
646770216	273	30.96	4	272	2	279	2.0e-39	155	COG1319	CO or xanthine dehydrogenase, FAD-binding subunit	284
646770217	1013	32.83	30	820	6	730	4.0e-121	429	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
646770218	204	62.69	4	194	1	191	2.0e-73	268	COG0163	3-polyprenyl-4-hydroxybenzoate decarboxylase	191
646770219	497	37.45	23	470	1	459	1.0e-104	373	COG0043	3-polyprenyl-4-hydroxybenzoate decarboxylase	477
646770220	313	31	1	298	1	296	5.0e-32	132	COG0583	DNA-binding transcriptional regulator, LysR family	297
646770221	479	42.41	3	472	1	472	1.0e-113	403	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
646770222	340	35.28	6	331	1	278	2.0e-55	209	COG1975	Xanthine and CO dehydrogenase maturation factor, XdhC/CoxF family	278
646770223	331	30.87	24	320	1	292	1.0e-28	120	COG0583	DNA-binding transcriptional regulator, LysR family	297
646770224	388	31.79	13	387	5	381	6.0e-54	204	COG0006	Xaa-Pro aminopeptidase	384
646770226	390	59.09	9	377	6	376	3.0e-129	455	COG3970	Fumarylacetoacetate (FAA) hydrolase family protein	379
646770228	297	25.2	174	296	4	126	5.0e-15	75.3	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
646770229	153	36.3	11	137	14	148	1.0e-21	95.6	COG2030	Acyl dehydratase	159
646770230	397	42.82	1	390	7	396	4.0e-97	348	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
646770231	381	44.73	1	380	1	387	4.0e-86	311	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
646770232	141	35.25	19	135	31	149	9.0e-14	69.4	COG2030	Acyl dehydratase	159
646770233	343	32.72	17	338	9	332	6.0e-64	237	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
646770234	177	28.47	11	154	8	151	2.0e-19	89.2	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
646770235	423	44.44	43	420	1	378	6.0e-79	288	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
646770236	277	47.52	34	271	15	255	7.0e-48	184	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
646770237	411	38.69	4	392	8	396	1.0e-80	293	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
646770238	574	29.98	6	551	3	540	1.0e-71	264	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
646770239	341	28.66	5	328	2	303	6.0e-31	128	COG3547	Transposase	303
646770240	656	27.95	358	643	3	291	7.0e-25	109	COG0741	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)	296
646770241	305	24.22	9	289	3	290	1.0e-22	100	COG1744	Basic membrane lipoprotein Med, periplasmic binding protein (PBP1-ABC) superfamily	345
646770242	441	32.34	138	438	33	330	1.0e-39	158	COG0642	Signal transduction histidine kinase	336
646770244	224	44.64	1	214	1	223	3.0e-50	191	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
646770246	393	34.03	14	383	4	386	2.0e-46	180	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
646770247	476	19.19	20	456	1	402	2.0e-14	74.2	COG0446	NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase	415
646770249	378	29.29	10	368	6	381	3.0e-37	149	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
646770250	265	36.4	6	255	11	260	3.0e-46	178	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
646770251	290	37.22	11	275	7	272	9.0e-48	184	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
646770252	356	48.01	1	349	3	352	4.0e-111	394	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
646770253	354	24.32	6	350	3	358	2.0e-29	123	COG0687	Spermidine/putrescine-binding periplasmic protein	363
646770254	317	29.57	1	297	1	297	6.0e-33	135	COG0583	DNA-binding transcriptional regulator, LysR family	297
646770255	289	24.75	5	289	4	292	5.0e-21	95.4	COG0583	DNA-binding transcriptional regulator, LysR family	297
646770256	463	21.43	15	428	9	383	3.0e-11	63.7	COG2814	Predicted arabinose efflux permease, MFS family	394
646770257	371	25.32	1	371	1	382	3.0e-28	119	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
646770261	237	45.93	8	216	3	204	5.0e-46	177	COG3316	Transposase (or an inactivated derivative)	215
646770262	652	36.53	284	644	23	408	1.0e-44	175	COG0840	Methyl-accepting chemotaxis protein	408
646770265	384	23.42	15	384	2	354	4.0e-44	172	COG3203	Outer membrane protein (porin)	354
646770266	541	26.63	3	375	1	382	1.0e-50	194	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
646770267	256	32.67	1	247	8	254	7.0e-33	134	COG3836	2-keto-3-deoxy-L-rhamnonate aldolase RhmA	255
646770269	267	37.98	8	262	4	260	1.0e-46	180	COG3971	2-keto-4-pentenoate hydratase	264
646770270	291	23.32	17	286	1	281	8.0e-20	91.3	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
646770272	461	19.59	20	445	30	448	4.0e-14	73.3	COG2271	Sugar phosphate permease	448
646770273	246	34.26	13	243	4	251	9.0e-31	127	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
646770274	488	24.68	1	384	2	383	9.0e-45	174	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
646770275	283	39.6	38	283	24	266	5.0e-64	237	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
646770276	270	31.98	2	247	1	246	3.0e-31	129	COG1414	DNA-binding transcriptional regulator, IclR family	246
646770278	283	39.34	16	282	1	265	3.0e-63	235	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
646770279	507	26.51	12	384	2	372	2.0e-46	180	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
646770280	447	21.33	70	429	55	388	1.0e-08	55.2	COG2814	Predicted arabinose efflux permease, MFS family	394
646770283	450	19.71	31	435	21	409	1.0e-14	75.3	COG2223	Nitrate/nitrite transporter NarK	417
646770285	304	39.22	1	302	8	311	8.0e-52	197	COG0657	Acetyl esterase/lipase	312
646770286	659	33.82	154	559	3	388	3.0e-60	227	COG2072	Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD	443
646770288	187	13.97	12	133	2	137	4.0e-06	44.8	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
646770289	246	30.58	6	246	5	245	2.0e-33	136	COG1414	DNA-binding transcriptional regulator, IclR family	246
646770290	237	45.93	8	216	3	204	4.0e-46	177	COG3316	Transposase (or an inactivated derivative)	215
646770292	233	34.97	26	207	20	201	3.0e-27	115	COG1802	DNA-binding transcriptional regulator, GntR family	230
646770293	341	28.96	5	328	2	303	6.0e-31	128	COG3547	Transposase	303
646770295	341	28.66	5	328	2	303	6.0e-31	128	COG3547	Transposase	303
646770296	464	26.57	26	421	4	336	1.0e-48	188	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
646770297	415	26.03	36	411	20	393	8.0e-42	164	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
646770298	415	24.74	29	409	15	391	4.0e-38	152	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
646770299	218	57.14	1	217	6	222	8.0e-67	246	COG2011	ABC-type methionine transport system, permease component	222
646770300	388	49.03	30	387	2	339	3.0e-109	388	COG1135	ABC-type methionine transport system, ATPase component	339
646770301	279	42.48	15	279	4	268	2.0e-72	265	COG1464	ABC-type metal ion transport system, periplasmic component/surface antigen	268
646770302	358	33.53	23	350	11	331	1.0e-44	173	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
646770304	198	28.27	1	191	5	191	5.0e-43	167	COG5553	Predicted metal-dependent enzyme of the double-stranded beta helix superfamily	191
646770305	535	33.64	125	233	1	109	1.0e-10	62.2	COG0607	Rhodanese-related sulfurtransferase	110
646770306	303	27.67	1	298	1	295	2.0e-29	123	COG0583	DNA-binding transcriptional regulator, LysR family	297
646770307	323	33.23	10	322	4	328	3.0e-38	152	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
646770308	408	24.54	29	397	14	387	1.0e-41	164	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
646770309	362	33.04	20	357	8	334	6.0e-46	178	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
646770310	344	27.44	18	327	1	312	3.0e-28	119	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
646770311	278	51.57	25	278	1	245	2.0e-83	302	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
646770312	347	30.59	91	343	3	256	2.0e-29	123	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
646770313	337	31.21	10	329	3	319	5.0e-27	115	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
646770314	198	23.19	13	191	5	202	4.0e-11	61.5	COG0778	Nitroreductase	207
646770315	177	23.02	34	171	3	133	1.0e-08	53.1	COG1765	Uncharacterized OsmC-related protein	137
646770317	413	22.59	31	409	14	393	9.0e-44	171	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
646770318	406	31.94	76	405	17	334	8.0e-41	161	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
646770319	353	20.23	4	341	31	328	2.0e-12	67.1	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
646770320	539	29.8	11	538	8	554	2.0e-84	307	COG0747	ABC-type transport system, periplasmic component	556
646770321	349	43.56	1	320	1	316	6.0e-79	287	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
646770322	547	31.5	24	544	14	554	1.0e-80	294	COG0747	ABC-type transport system, periplasmic component	556
646770323	578	54.23	1	569	2	535	0.0e+00	633	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
646770324	326	49.82	53	325	15	289	1.0e-66	247	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
646770325	326	50.78	7	325	2	313	2.0e-85	309	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
646770326	534	32.07	1	531	3	552	3.0e-87	316	COG0747	ABC-type transport system, periplasmic component	556
646770328	266	54.85	23	258	1	237	8.0e-83	300	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
646770329	289	50.75	9	273	1	249	4.0e-77	281	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
646770330	607	43.88	1	289	3	295	2.0e-50	193	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
646770331	392	31.01	30	380	2	358	3.0e-52	199	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
646770332	336	30.56	1	296	1	296	6.0e-24	105	COG0583	DNA-binding transcriptional regulator, LysR family	297
646770333	501	23.43	38	491	1	433	3.0e-46	179	COG2072	Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD	443
646770334	188	28.89	7	184	11	176	2.0e-10	58.9	COG4950	N-terminal domain of uncharacterized protein YciW (function unknown)	193
646770335	191	29.26	5	190	1	177	4.0e-22	97.9	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
646770336	391	31.84	29	377	1	356	7.0e-51	194	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
646770337	440	28.57	29	417	10	336	6.0e-46	178	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
646770338	96	61.05	1	95	1	95	2.0e-31	127	COG0234	Co-chaperonin GroES (HSP10)	96
646770339	546	48.08	1	531	1	521	0.0e+00	484	COG0459	Chaperonin GroEL (HSP60 family)	524
646770340	451	31.67	26	423	4	335	3.0e-48	186	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
646770341	449	30	38	422	11	335	5.0e-42	165	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
646770343	407	21.46	13	401	7	393	3.0e-28	119	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
646770344	529	32.96	10	528	16	554	7.0e-83	301	COG0747	ABC-type transport system, periplasmic component	556
646770345	283	27.24	1	265	36	297	3.0e-21	95.8	COG0583	DNA-binding transcriptional regulator, LysR family	297
646770348	568	27.07	237	550	23	283	2.0e-22	101	COG4974	Site-specific recombinase XerD	300
646770350	331	38.8	16	329	1	313	3.0e-52	199	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
646770351	315	27.83	8	314	31	317	9.0e-34	137	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
646770354	275	27.27	18	268	23	282	8.0e-14	71.3	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
646770355	277	28.49	44	196	43	214	8.0e-20	91.1	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
646770357	761	53.56	1	432	13	432	0.0e+00	562	COG0281	Malic enzyme	432
646770358	325	21.99	16	296	1	273	6.0e-20	91.6	COG0583	DNA-binding transcriptional regulator, LysR family	297
646770359	304	22.92	2	295	1	291	1.0e-24	107	COG0583	DNA-binding transcriptional regulator, LysR family	297
646770360	376	37.07	1	374	11	368	7.0e-79	287	COG3616	D-serine deaminase, pyridoxal phosphate-dependent	368
646770361	136	41.03	16	131	10	126	2.0e-26	111	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
646770362	443	39.76	2	419	4	412	5.0e-85	308	COG1301	Na+/H+-dicarboxylate symporter	415
646770363	466	29.57	27	449	5	436	8.0e-55	208	COG0076	Glutamate or tyrosine decarboxylase or a related PLP-dependent protein	460
646770364	205	22.56	8	201	2	190	5.0e-07	48.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
646770366	235	18.85	5	235	25	281	4.0e-06	45.1	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
646770367	262	36.58	20	260	4	250	9.0e-40	157	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
646770369	206	33.51	7	194	8	198	1.0e-26	113	COG4339	Predicted metal-dependent phosphohydrolase, HD superfamily	208
646770370	91	51.11	1	90	1	89	5.0e-20	89.5	COG1937	DNA-binding transcriptional regulator, FrmR family	89
646770371	369	69.92	1	369	1	366	0.0e+00	566	COG1062	Zn-dependent alcohol dehydrogenase	366
646770380	306	25	31	138	15	122	1.0e-08	54.2	COG1846	DNA-binding transcriptional regulator, MarR family	126
646770384	338	41.51	2	315	1	314	3.0e-87	315	COG0180	Tryptophanyl-tRNA synthetase	314
646770386	573	40.04	26	564	27	573	0.0e+00	517	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
646770387	158	22.48	19	141	2	128	1.0e-10	59.2	COG2703	Hemerythrin	144
646770389	372	33.08	1	371	2	397	2.0e-74	272	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
646770390	326	55.11	4	325	2	324	7.0e-129	453	COG0022	Pyruvate/2-oxoglutarate/acetoin dehydrogenase complex, dehydrogenase (E1) component	324
646770391	371	42.54	12	352	4	358	6.0e-106	377	COG1071	TPP-dependent pyruvate or acetoin dehydrogenase subunit alpha	358
646770392	261	34.96	2	246	2	243	9.0e-40	157	COG1414	DNA-binding transcriptional regulator, IclR family	246
646770393	447	16.62	81	442	79	445	1.0e-11	64.4	COG2271	Sugar phosphate permease	448
646770394	148	47.59	4	148	2	146	9.0e-43	166	COG0757	3-dehydroquinate dehydratase	146
646770396	573	16.75	1	553	1	535	2.0e-33	137	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
646770397	281	42.69	17	262	1	250	6.0e-38	151	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
646770398	323	25.81	191	314	3	126	2.0e-15	76.8	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
646770399	933	30.95	553	930	31	411	3.0e-56	214	COG2124	Cytochrome P450	411
646770401	440	23.73	4	405	25	430	3.0e-42	166	COG4325	Uncharacterized membrane protein	464
646770402	225	35.68	1	210	4	207	9.0e-42	163	COG0288	Carbonic anhydrase	207
646770403	404	32.16	23	388	7	366	9.0e-48	184	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
646770404	291	33.78	1	290	3	297	1.0e-38	153	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
646770405	646	51.2	391	639	4	250	2.0e-85	310	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
646770406	244	55.37	1	241	3	236	3.0e-85	308	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
646770408	249	37.08	1	241	4	265	7.0e-50	190	COG1912	S-adenosylmethionine hydrolase (SAM-hydroxide adenosyltransferase)	268
646770409	325	32.65	11	296	6	289	9.0e-37	147	COG0583	DNA-binding transcriptional regulator, LysR family	297
646770410	273	39.33	11	273	14	279	4.0e-77	281	COG0656	Aldo/keto reductase, related to diketogulonate reductase	280
646770412	300	32.88	4	294	3	291	3.0e-35	142	COG0583	DNA-binding transcriptional regulator, LysR family	297
646770413	518	28.76	8	235	4	236	2.0e-28	120	COG3629	DNA-binding transcriptional activator of the SARP family	280
646770414	463	19.76	7	399	4	385	1.0e-12	68.2	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
646770416	222	40	24	221	13	210	4.0e-33	134	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
646770417	312	33.23	17	311	34	347	1.0e-32	134	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
646770421	297	22.31	49	297	1	231	3.0e-12	66.2	COG2801	Transposase InsO and inactivated derivatives	232
646770422	133	28.57	19	118	2	106	2.0e-09	54.9	COG2963	Transposase and inactivated derivatives	116
646770423	194	29.13	1	189	1	203	2.0e-19	89.1	COG0625	Glutathione S-transferase	211
646770425	347	35.78	218	326	18	126	1.0e-21	98	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
646770427	238	18.57	1	139	1	136	1.0e-05	43.7	COG1943	REP element-mobilizing transposase RayT	136
646770428	195	28.81	21	190	7	181	3.0e-25	108	COG2930	Lipid-binding SYLF domain	227
646770429	407	21.77	119	405	102	378	2.0e-07	50.7	COG2327	Polysaccharide pyruvyl transferase family protein WcaK	385
646770434	210	40.48	2	209	1	210	3.0e-49	188	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
646770438	150	28.46	21	138	15	143	1.0e-09	55.8	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
646770439	572	37.92	6	562	36	581	2.0e-111	396	COG4425	Uncharacterized membrane protein	588
646770440	242	40.44	17	234	7	228	2.0e-36	145	COG2186	DNA-binding transcriptional regulator, FadR family	241
646770441	375	26.57	58	336	33	313	4.0e-27	116	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
646770442	516	48.1	2	500	1	497	0.0e+00	578	COG1129	ABC-type sugar transport system, ATPase component	500
646770443	326	35.2	17	319	14	314	4.0e-41	162	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
646770444	328	38.39	18	326	5	311	4.0e-45	175	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
646770446	517	24.44	100	497	14	398	8.0e-42	165	COG1914	Mn2+ and Fe2+ transporters of the NRAMP family	416
646770447	387	30.33	8	386	17	409	6.0e-63	235	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
646770448	225	44.59	1	225	1	229	3.0e-59	221	COG3342	Uncharacterized conserved protein, Ntn-hydrolase superfamily	265
646770449	143	34.59	5	136	1	130	9.0e-26	109	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
646770450	452	27.52	8	434	9	440	7.0e-55	208	COG2072	Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD	443
646770451	307	29.77	9	304	2	294	8.0e-32	131	COG0583	DNA-binding transcriptional regulator, LysR family	297
646770452	383	25.07	32	366	5	341	4.0e-39	155	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
646770453	401	46.2	2	368	1	352	4.0e-110	391	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
646770454	351	26.8	1	347	2	353	5.0e-40	158	COG0687	Spermidine/putrescine-binding periplasmic protein	363
646770455	418	43.11	192	416	60	284	4.0e-58	219	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
646770456	275	41	12	272	7	267	7.0e-55	207	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
646770458	107	25.96	11	106	1	104	1.0e-14	71.9	COG2329	Heme-degrading monooxygenase HmoA and related ABM domain proteins	105
646770460	297	53.02	4	284	8	287	4.0e-70	258	COG2962	Uncharacterized membrane protein RarD, contains two EamA domains	293
646770463	481	39.79	1	479	29	502	8.0e-110	391	COG0513	Superfamily II DNA and RNA helicase	513
646770466	248	47.41	7	244	2	249	5.0e-41	161	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
646770467	273	35	40	273	5	237	1.0e-47	183	COG3473	Maleate cis-trans isomerase	238
646770468	400	37.18	36	383	2	356	2.0e-58	219	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
646770469	299	46.15	1	298	3	297	2.0e-51	196	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
646770470	602	53.97	333	583	2	250	6.0e-85	308	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
646770471	243	58.4	1	237	1	237	2.0e-81	295	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
646770472	282	36.33	5	267	12	264	6.0e-61	227	COG3665	Uncharacterized conserved protein YcgI, DUF1989 family	264
646770473	414	27.36	1	414	5	379	1.0e-43	170	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
646770474	164	20.51	1	154	1	155	2.0e-19	88.4	COG2606	Cys-tRNA(Pro) deacylase, prolyl-tRNA editing enzyme YbaK/EbsC	155
646770477	623	18.02	16	607	1	589	1.0e-45	178	COG1874	Beta-galactosidase GanA	673
646770479	248	20.49	5	248	50	280	3.0e-12	65.9	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
646770484	299	22.08	3	288	1	294	5.0e-29	121	COG0451	Nucleoside-diphosphate-sugar epimerase	314
646770486	577	42.29	25	573	10	510	0.0e+00	473	COG0155	Sulfite reductase, beta subunit (hemoprotein)	510
646770487	612	47.17	15	612	1	587	0.0e+00	560	COG0369	Sulfite reductase, alpha subunit (flavoprotein)	587
646770490	671	54.36	19	542	2	521	0.0e+00	671	COG4670	Acyl CoA:acetate/3-ketoacid CoA transferase	527
646770495	551	35.29	229	549	4	303	5.0e-57	215	COG0492	Thioredoxin reductase	305
646770496	299	41.39	2	296	4	297	1.0e-63	236	COG4360	ATP adenylyltransferase (5',5'''-P-1,P-4-tetraphosphate phosphorylase II)	298
646770497	161	57.76	1	161	3	162	1.0e-65	242	COG1839	Adenosine/AMP kinase	162
646770501	529	34.01	196	517	62	408	3.0e-49	189	COG0840	Methyl-accepting chemotaxis protein	408
646770502	507	30.71	1	471	3	479	2.0e-78	287	COG1129	ABC-type sugar transport system, ATPase component	500
646770503	308	32.7	4	307	1	314	3.0e-27	116	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
646770504	291	34.13	1	291	4	293	1.0e-30	126	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
646770505	421	27.56	26	370	1	342	1.0e-38	154	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
646770506	418	25.7	4	413	3	429	1.0e-35	144	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
646770507	289	40.55	1	289	3	293	1.0e-57	216	COG1175	ABC-type sugar transport system, permease component	295
646770508	283	40.86	7	281	2	278	3.0e-47	182	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
646770512	247	39.04	1	244	3	250	1.0e-47	183	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
646770517	511	35.03	140	508	13	406	4.0e-43	169	COG0840	Methyl-accepting chemotaxis protein	408
646770518	391	28.94	24	365	5	351	5.0e-51	195	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
646770519	286	34.49	1	280	6	290	9.0e-41	160	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
646770520	329	34.22	14	309	1	298	2.0e-40	160	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
646770521	254	46	1	246	1	250	3.0e-73	268	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
646770522	235	49.58	3	232	2	237	8.0e-76	276	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
646770523	287	24.65	19	287	1	280	2.0e-19	89.8	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
646770524	287	32.66	8	243	1	246	1.0e-27	117	COG0583	DNA-binding transcriptional regulator, LysR family	297
646770525	376	33.08	83	341	4	253	3.0e-38	153	COG2220	L-ascorbate metabolism protein UlaG, beta-lactamase superfamily	258
646770526	204	26.5	5	204	4	201	1.0e-06	46.6	COG1309	DNA-binding transcriptional regulator, AcrR family	201
646770530	422	46.72	14	419	3	413	5.0e-96	345	COG4941	Predicted RNA polymerase sigma factor, contains C-terminal TPR domain	415
646770531	122	43.36	1	113	1	113	4.0e-29	119	COG3795	Uncharacterized conserved protein	123
646770532	861	77.73	1	859	1	850	0.0e+00	1475	COG1049	Aconitase B	852
646770533	200	30.54	1	200	5	207	3.0e-44	171	COG5588	Uncharacterized protein	207
646770534	263	33.96	6	257	16	280	5.0e-44	171	COG5486	Predicted metal-binding membrane protein	283
646770535	316	26.04	32	313	1	281	4.0e-19	89	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
646770536	185	25.97	5	184	18	196	3.0e-06	45.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
646770539	509	27.09	1	448	3	403	1.0e-41	164	COG3025	Inorganic triphosphatase YgiF, contains CYTH and CHAD domains	432
646770542	889	37.87	8	887	96	933	0.0e+00	875	COG0178	Excinuclease UvrABC ATPase subunit	935
646770544	446	18.3	63	436	48	443	7.0e-17	82.2	COG2211	Na+/melibiose symporter or related transporter	467
646770547	351	31.8	47	346	3	296	5.0e-37	148	COG0583	DNA-binding transcriptional regulator, LysR family	297
646770549	344	36.62	6	323	25	318	1.0e-58	220	COG0226	ABC-type phosphate transport system, periplasmic component	318
646770555	138	29.86	7	134	19	162	1.0e-07	49.4	COG4961	Flp pilus assembly protein TadG	185
646770556	222	35.42	62	204	11	154	7.0e-31	127	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
646770560	297	27	4	296	1	296	1.0e-31	130	COG0583	DNA-binding transcriptional regulator, LysR family	297
646770561	249	41.09	1	247	1	251	2.0e-44	172	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
646770562	441	20.48	25	434	21	433	2.0e-16	80.2	COG2271	Sugar phosphate permease	448
646770563	281	49.17	5	246	3	243	2.0e-83	302	COG3959	Transketolase, N-terminal subunit	243
646770564	332	45.22	19	331	1	312	7.0e-102	364	COG3958	Transketolase, C-terminal subunit	312
646770566	432	37.94	55	416	50	414	6.0e-87	314	COG4553	Poly-beta-hydroxyalkanoate depolymerase	415
646770568	78	42.11	1	76	2	77	2.0e-12	63.9	COG4118	Antitoxin component of toxin-antitoxin stability system, DNA-binding transcriptional repressor	84
646770569	125	41.67	3	118	4	123	4.0e-25	106	COG3744	PIN domain nuclease, a component of toxin-antitoxin system (PIN domain)	130
646770570	248	39.68	1	245	2	250	2.0e-46	179	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
646770573	167	37.66	1	149	4	154	1.0e-17	82.7	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
646770574	153	36.24	1	144	4	151	2.0e-16	78.1	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
646770576	260	29.61	51	255	9	214	8.0e-32	130	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
646770578	156	35.14	1	146	4	151	5.0e-16	77.3	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
646770579	328	39.1	1	325	4	335	1.0e-84	306	COG1064	D-arabinose 1-dehydrogenase, Zn-dependent alcohol dehydrogenase family	339
646770580	111	33.33	16	111	15	105	3.0e-08	50.5	COG4654	Cytochrome c551/c552	110
646770582	338	26.73	21	338	3	332	9.0e-29	121	COG0642	Signal transduction histidine kinase	336
646770583	273	42.06	6	238	2	228	3.0e-52	198	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
646770585	1835	36.24	294	1141	2	849	0.0e+00	499	COG3899	Predicted ATPase	849
646770586	227	35.98	11	199	1	182	3.0e-25	109	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
646770588	178	40.61	10	173	9	169	1.0e-23	102	COG3652	Predicted outer membrane protein	170
646770589	472	34.56	17	471	1	457	3.0e-77	282	COG0277	FAD/FMN-containing dehydrogenase	459
646770590	419	39.53	17	397	1	358	1.0e-80	293	COG1304	FMN-dependent dehydrogenase, includes L-lactate dehydrogenase and type II isopentenyl diphosphate isomerase	360
646770591	515	51.73	112	515	6	381	0.0e+00	467	COG2721	Altronate dehydratase	381
646770592	428	20	2	409	24	439	4.0e-29	123	COG2271	Sugar phosphate permease	448
646770593	377	27.99	1	372	14	393	3.0e-57	215	COG0246	Mannitol-1-phosphate/altronate dehydrogenases	473
646770594	342	34.47	3	340	1	348	8.0e-60	224	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
646770595	236	38.43	1	236	1	239	2.0e-41	162	COG2186	DNA-binding transcriptional regulator, FadR family	241
646770596	325	37.89	18	273	36	281	5.0e-45	175	COG1446	Isoaspartyl peptidase or L-asparaginase, Ntn-hydrolase superfamily	307
646770597	332	23.68	9	286	7	315	8.0e-23	101	COG0687	Spermidine/putrescine-binding periplasmic protein	363
646770598	306	24.58	1	297	1	297	6.0e-24	105	COG0583	DNA-binding transcriptional regulator, LysR family	297
646770599	416	31.58	22	409	27	399	3.0e-48	186	COG1228	Imidazolonepropionase or related amidohydrolase	406
646770600	396	30.99	17	390	18	380	2.0e-39	156	COG0006	Xaa-Pro aminopeptidase	384
646770601	295	42.6	16	291	8	284	1.0e-53	203	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
646770602	353	25.84	1	306	1	314	7.0e-30	125	COG0687	Spermidine/putrescine-binding periplasmic protein	363
646770603	350	47.19	1	350	3	352	6.0e-114	404	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
646770604	287	36.23	18	282	2	260	4.0e-46	178	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
646770605	431	22.92	46	428	20	393	3.0e-15	76.8	COG2814	Predicted arabinose efflux permease, MFS family	394
646770606	625	47.44	83	584	47	552	0.0e+00	495	COG1626	Neutral trehalase	558
646770607	497	26.25	82	436	48	452	2.0e-26	113	COG3511	Phospholipase C	527
646770608	638	51.11	7	638	1	627	0.0e+00	725	COG3158	K+ transporter	627
646770609	239	24.44	9	188	2	181	2.0e-08	53.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
646770611	328	36.07	15	314	2	293	2.0e-71	262	COG1131	ABC-type multidrug transport system, ATPase component	293
646770612	371	31.43	125	368	40	281	6.0e-22	98.4	COG0842	ABC-type multidrug transport system, permease component	286
646770613	505	37.38	84	502	35	443	3.0e-46	179	COG1538	Outer membrane protein TolC	457
646770614	431	43.47	29	426	5	400	5.0e-84	305	COG3135	Predicted benzoate:H+ symporter BenE	402
646770615	263	38.31	8	260	2	249	1.0e-34	140	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
646770616	340	33.02	109	321	9	213	1.0e-34	140	COG0543	NAD(P)H-flavin reductase	252
646770617	163	48.47	1	163	2	164	1.0e-46	178	COG5517	3-phenylpropionate/cinnamic acid dioxygenase, small subunit	164
646770618	455	26.51	29	441	4	352	7.0e-55	208	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
646770620	305	31.29	1	273	1	271	9.0e-32	130	COG0583	DNA-binding transcriptional regulator, LysR family	297
646770621	257	33.33	4	256	15	269	3.0e-40	158	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
646770622	229	52.61	1	227	1	230	4.0e-67	247	COG4215	ABC-type arginine transport system, permease component	230
646770623	237	51.75	7	234	1	228	9.0e-71	260	COG4160	ABC-type arginine/histidine transport system, permease component	228
646770624	255	73.71	1	251	4	253	2.0e-115	408	COG4598	ABC-type histidine transport system, ATPase component	256
646770627	110	32.73	1	109	3	106	2.0e-13	67.7	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
646770631	110	32.73	1	109	3	106	2.0e-13	67.7	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
646770632	103	30.43	3	94	1	90	1.0e-14	71.1	COG2350	Uncharacterized conserved protein YciI, contains a putative active-site phosphohistidine	92
646770633	290	30.17	53	289	1	226	7.0e-34	137	COG3485	Protocatechuate 3,4-dioxygenase beta subunit	226
646770634	355	35.85	10	349	7	377	6.0e-72	264	COG1454	Alcohol dehydrogenase, class IV	377
646770635	488	48.22	3	477	1	468	0.0e+00	519	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
646770638	309	26.26	7	298	6	297	3.0e-32	132	COG0583	DNA-binding transcriptional regulator, LysR family	297
646770639	423	23.79	12	396	12	384	1.0e-23	104	COG2814	Predicted arabinose efflux permease, MFS family	394
646770641	397	48.11	1	394	2	389	6.0e-125	440	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
646770642	464	19.03	85	455	48	382	4.0e-10	59.8	COG2814	Predicted arabinose efflux permease, MFS family	394
646770643	290	29.01	3	290	2	291	6.0e-28	118	COG0583	DNA-binding transcriptional regulator, LysR family	297
646770644	342	46.43	36	342	6	313	3.0e-94	338	COG3965	Predicted Co/Zn/Cd cation transporter, cation efflux family	314
646770646	271	37.16	33	193	40	217	1.0e-25	110	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
646770647	101	42.05	9	96	3	89	3.0e-19	86.4	COG1254	Acylphosphatase	92
646770651	544	29.98	35	509	4	460	2.0e-78	286	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
646770655	148	29.14	1	144	5	149	7.0e-17	79.7	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
646770656	244	27.51	11	236	4	222	3.0e-21	95.4	COG1011	FMN phosphatase YigB, HAD superfamily	229
646770658	251	40.48	1	251	1	252	2.0e-55	209	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
646770659	266	38.97	5	266	3	273	1.0e-40	160	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
646770660	557	53.88	50	557	41	556	0.0e+00	563	COG1626	Neutral trehalase	558
646770662	611	24.09	42	578	4	494	2.0e-50	194	COG2939	Carboxypeptidase C (cathepsin A)	498
646770664	136	25	4	126	2	132	2.0e-07	48.3	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
646770665	177	37.61	19	135	11	127	2.0e-19	88.8	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
646770666	357	25.29	3	347	11	355	1.0e-23	104	COG0628	Predicted PurR-regulated permease PerM	355
646770669	528	30.8	41	498	29	430	4.0e-60	226	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
646770672	914	40.82	30	882	1	761	0.0e+00	753	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
646770674	278	43.18	14	276	7	269	3.0e-65	242	COG4455	Protein of avirulence locus involved in temperature-dependent protein secretion	273
646770675	172	35.71	13	165	8	154	1.0e-21	96.6	COG3518	Predicted component of the type VI protein secretion system	157
646770676	626	45.21	1	626	1	621	0.0e+00	678	COG3519	Type VI protein secretion system component VasA	621
646770677	355	38.51	27	344	16	334	1.0e-78	287	COG3520	Predicted component of the type VI protein secretion system	335
646770678	356	29.61	9	356	1	341	2.0e-27	116	COG3515	Predicted component of the type VI protein secretion system	346
646770679	322	21.02	158	321	6	181	6.0e-07	48.6	COG3539	Pilin (type 1 fimbria component protein)	184
646770681	1144	20.24	443	1093	8	651	4.0e-27	117	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
646770682	88	37.93	1	87	11	97	2.0e-06	44.2	COG4104	Zn-binding Pro-Ala-Ala-Arg (PAAR) domain, incolved in TypeVI secretion	98
646770683	844	38.93	30	585	17	546	0.0e+00	494	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
646770684	1321	35.12	56	1299	1	1184	0.0e+00	762	COG3523	Type VI protein secretion system component VasK	1188
646770685	444	36.73	48	292	17	260	9.0e-54	204	COG3455	Type VI protein secretion system component VasF	262
646770686	449	47.56	1	448	1	446	1.0e-128	453	COG3522	Predicted component of the type VI protein secretion system	446
646770687	181	33.56	14	162	3	149	8.0e-33	133	COG3521	Predicted component of the type VI protein secretion system	159
646770688	160	32.03	1	146	1	153	2.0e-35	141	COG3157	Type VI protein secretion system component Hcp (secreted cytotoxin)	162
646770689	517	62.12	17	515	1	495	0.0e+00	775	COG3517	Predicted component of the type VI protein secretion system	495
646770690	559	35.29	403	555	41	190	3.0e-28	120	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
646770692	186	25.14	8	184	1	182	2.0e-09	55.6	COG3539	Pilin (type 1 fimbria component protein)	184
646770693	946	43.29	91	901	24	824	0.0e+00	698	COG3188	Outer membrane usher protein FimD/PapC	835
646770694	257	39.65	10	236	12	226	3.0e-53	202	COG3121	P pilus assembly protein, chaperone PapD	235
646770695	182	25.82	5	182	3	184	3.0e-15	75.2	COG3539	Pilin (type 1 fimbria component protein)	184
646770696	216	33.97	4	212	1	205	1.0e-38	153	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
646770698	475	26.22	1	443	9	452	1.0e-29	124	COG0531	Amino acid transporter	466
646770699	478	27.68	11	453	17	458	4.0e-29	122	COG0531	Amino acid transporter	466
646770700	500	30.79	14	471	1	446	1.0e-48	187	COG1538	Outer membrane protein TolC	457
646770701	1019	26.93	2	1005	1	1009	0.0e+00	642	COG0841	Multidrug efflux pump subunit AcrB	1009
646770702	376	24.73	13	370	1	366	4.0e-17	82.5	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
646770703	324	34.59	55	237	1	178	1.0e-20	94.2	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
646770704	403	28.31	120	389	3	255	4.0e-33	135	COG1192	Cellulose biosynthesis protein BcsQ	259
646770706	498	22.48	18	491	8	438	4.0e-45	176	COG2610	H+/gluconate symporter or related permease	442
646770707	347	22.66	12	342	8	298	1.0e-30	127	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
646770708	123	29.51	3	123	1	121	3.0e-21	93.6	COG3791	Uncharacterized conserved protein	133
646770710	246	44.4	6	237	2	227	3.0e-56	211	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
646770711	447	29.29	159	441	36	327	5.0e-32	132	COG0642	Signal transduction histidine kinase	336
646770712	473	29.71	12	445	19	455	6.0e-30	125	COG0531	Amino acid transporter	466
646770713	419	43.58	10	417	4	409	0.0e+00	497	COG2235	Arginine deiminase	409
646770715	418	21.7	12	408	1	384	1.0e-16	81.4	COG2814	Predicted arabinose efflux permease, MFS family	394
646770717	475	14.98	41	445	35	409	6.0e-10	59.5	COG0738	Fucose permease	422
646770718	594	33.11	6	593	9	538	4.0e-116	412	COG0405	Gamma-glutamyltranspeptidase	539
646770719	225	33.92	5	223	15	241	2.0e-29	122	COG2186	DNA-binding transcriptional regulator, FadR family	241
646770720	441	34.27	37	421	1	384	9.0e-56	211	COG3550	Serine/threonine protein kinase HipA, toxin component of the HipAB toxin-antitoxin module	392
646770725	521	23.48	82	323	4	215	3.0e-19	90.5	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
646770726	386	32.98	12	381	6	339	7.0e-71	261	COG3693	Endo-1,4-beta-xylanase, GH35 family	345
646770728	384	24.93	1	355	1	346	7.0e-29	121	COG3203	Outer membrane protein (porin)	354
646770729	363	42.94	24	352	1	332	3.0e-80	292	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
646770730	415	24.88	1	409	9	426	2.0e-28	120	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
646770731	344	37.5	32	335	1	289	3.0e-53	202	COG1175	ABC-type sugar transport system, permease component	295
646770732	276	38.21	1	275	3	281	8.0e-52	197	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
646770733	445	42.48	3	436	1	451	2.0e-130	459	COG2723	Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase	460
646770734	376	50.98	1	357	1	338	4.0e-116	411	COG3839	ABC-type sugar transport system, ATPase component	338
646770736	129	33.6	1	121	3	122	4.0e-14	70.7	COG3744	PIN domain nuclease, a component of toxin-antitoxin system (PIN domain)	130
646770737	349	44.44	6	336	1	333	1.0e-78	286	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
646770738	431	26.62	8	429	4	428	2.0e-38	153	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
646770739	282	41.13	1	282	14	294	6.0e-61	227	COG1175	ABC-type sugar transport system, permease component	295
646770740	276	37.72	1	275	1	281	4.0e-52	198	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
646770741	376	48.64	1	368	1	338	2.0e-114	405	COG3839	ABC-type sugar transport system, ATPase component	338
646770742	801	36.79	29	427	1	367	3.0e-70	260	COG1472	Periplasmic beta-glucosidase and related glycosidases	397
646770743	255	34.52	8	252	2	250	2.0e-40	159	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
646770744	292	41.22	1	286	13	307	1.0e-61	230	COG3386	Sugar lactone lactonase YvrE	307
646770745	341	32.93	9	340	1	328	1.0e-68	253	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
646770746	468	19.59	21	438	21	433	1.0e-14	74.9	COG2271	Sugar phosphate permease	448
646770747	594	43.32	8	576	10	572	0.0e+00	606	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
646770748	395	59.34	5	392	2	379	0.0e+00	477	COG3970	Fumarylacetoacetate (FAA) hydrolase family protein	379
646770749	480	46.54	4	479	1	471	0.0e+00	469	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
646770753	277	31.56	38	274	44	283	3.0e-17	82.7	COG5486	Predicted metal-binding membrane protein	283
646770754	253	53.73	1	252	7	237	6.0e-80	290	COG4312	Predicted dithiol-disulfide oxidoreductase, DUF899 family	247
646770758	493	29.75	24	386	34	337	2.0e-55	210	COG1858	Cytochrome c peroxidase	364
646770760	1031	30.24	437	925	5	502	8.0e-39	156	COG0651	Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit	504
646770761	124	36.52	10	124	4	114	5.0e-15	73.3	COG1006	Multisubunit Na+/H+ antiporter, MnhC subunit	115
646770763	114	44.34	1	102	3	108	3.0e-18	83.7	COG1320	Multisubunit Na+/H+ antiporter, MnhG subunit	113
646770766	175	30.62	18	175	5	158	2.0e-23	102	COG1863	Multisubunit Na+/H+ antiporter, MnhE subunit	158
646770767	260	32.83	1	260	9	270	2.0e-40	159	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
646770768	108	33.33	9	84	12	88	2.0e-10	57.5	COG1993	PII-like signaling protein	109
646770771	159	25	4	139	8	149	2.0e-14	71.6	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
646770772	111	29.13	1	103	8	110	2.0e-09	54.4	COG0640	DNA-binding transcriptional regulator, ArsR family	110
646770774	335	31.58	39	204	4	174	7.0e-21	95.1	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
646770775	191	27.27	7	137	3	167	2.0e-17	82.2	COG1335	Nicotinamidase-related amidase	205
646770778	373	38.55	35	365	1	331	3.0e-77	282	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
646770779	319	28.32	10	285	1	273	3.0e-40	159	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
646770780	439	25.78	15	422	24	435	5.0e-38	152	COG2271	Sugar phosphate permease	448
646770781	304	42.95	2	295	5	305	1.0e-47	183	COG0524	Sugar or nucleoside kinase, ribokinase family	311
646770782	239	21.86	31	211	2	178	1.0e-08	53.5	COG1309	DNA-binding transcriptional regulator, AcrR family	201
646770783	421	23.06	18	419	3	409	5.0e-48	185	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
646770784	460	36.74	25	458	5	456	1.0e-85	310	COG0493	NADPH-dependent glutamate synthase beta chain or related oxidoreductase	457
646770785	426	34.78	3	323	1	310	6.0e-79	288	COG0167	Dihydroorotate dehydrogenase	310
646770786	500	45.79	14	497	22	494	0.0e+00	466	COG1953	Cytosine/uracil/thiamine/allantoin permease	497
646770787	485	32.51	1	445	1	427	6.0e-101	361	COG0044	Dihydroorotase or related cyclic amidohydrolase	430
646770788	150	28.28	39	137	19	116	6.0e-06	43.8	COG1846	DNA-binding transcriptional regulator, MarR family	126
646770789	140	37.98	6	128	14	140	4.0e-20	90.7	COG1661	Predicted DNA-binding protein with PD1-like DNA-binding motif	141
646770790	195	32.45	7	154	6	156	8.0e-16	77.2	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
646770794	134	40.8	3	127	1	125	3.0e-28	117	COG2343	Uncharacterized conserved protein, DUF427 family	132
646770796	179	34.03	37	174	26	167	2.0e-10	58.9	COG3652	Predicted outer membrane protein	170
646770797	343	25.4	9	342	5	381	3.0e-27	116	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
646770799	857	49.4	30	857	2	772	0.0e+00	858	COG4993	Glucose dehydrogenase	773
646770800	607	25.19	1	218	1	261	2.0e-25	110	COG0561	Hydroxymethylpyrimidine pyrophosphatase and other HAD family phosphatases	264
646770806	294	44.6	1	277	1	272	7.0e-80	290	COG3546	Mn-containing catalase (includes spore coat protein CotJC)	277
646770807	404	36.36	150	401	1	234	8.0e-59	221	COG1018	Ferredoxin-NADP reductase	266
646770808	288	20.68	34	270	26	214	2.0e-07	49.9	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
646770811	380	23.44	10	380	1	354	1.0e-42	167	COG3203	Outer membrane protein (porin)	354
646770814	763	22.62	16	762	10	765	2.0e-91	330	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
646770817	235	54.51	3	233	1	230	1.0e-79	289	COG0479	Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit	234
646770819	302	29.51	6	291	5	288	5.0e-33	135	COG0583	DNA-binding transcriptional regulator, LysR family	297
646770820	276	31.56	1	276	1	298	6.0e-53	201	COG3246	Uncharacterized conserved protein, DUF849 family	298
646770821	499	35.71	25	385	3	340	2.0e-49	190	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
646770823	339	24.93	6	339	1	314	2.0e-25	110	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
646770824	443	23.28	1	438	4	431	2.0e-31	130	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
646770825	318	37.84	23	318	2	293	6.0e-60	224	COG1175	ABC-type sugar transport system, permease component	295
646770826	317	34.97	15	316	8	281	4.0e-53	201	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
646770828	371	50.14	1	347	1	338	3.0e-109	388	COG3839	ABC-type sugar transport system, ATPase component	338
646770829	339	45.19	1	333	1	338	2.0e-98	352	COG3839	ABC-type sugar transport system, ATPase component	338
646770831	329	46.18	1	323	1	322	1.0e-87	316	COG2376	Dihydroxyacetone kinase	323
646770834	135	29.46	26	131	22	132	7.0e-14	69.6	COG1765	Uncharacterized OsmC-related protein	137
646770835	305	31.93	1	303	1	326	9.0e-45	174	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
646770838	305	30.63	1	303	1	326	1.0e-41	164	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
646770839	181	26.74	8	171	5	176	2.0e-12	65.6	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
646770840	224	28.1	22	224	3	205	3.0e-23	102	COG0778	Nitroreductase	207
646770843	469	36.07	13	468	1	456	3.0e-84	306	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
646770845	387	32.14	45	380	17	345	2.0e-38	153	COG0628	Predicted PurR-regulated permease PerM	355
646770847	359	29.92	1	350	14	369	1.0e-22	100	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
646770848	1057	29.03	29	1039	1	1008	0.0e+00	766	COG0841	Multidrug efflux pump subunit AcrB	1009
646770849	487	31.36	49	487	18	456	4.0e-42	166	COG1538	Outer membrane protein TolC	457
646770852	318	35.32	53	251	44	239	2.0e-42	166	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
646770853	659	33.5	15	597	2	533	2.0e-91	330	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
646770854	245	27.35	12	245	6	213	3.0e-30	125	COG3047	Outer membrane protein W	213
646770855	992	27.04	140	979	46	763	1.0e-74	275	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
646770856	287	27.23	1	186	8	190	2.0e-22	100	COG0437	Fe-S-cluster-containing dehydrogenase component	203
646770857	851	27.74	21	823	5	765	1.0e-75	278	COG2366	Acyl-homoserine lactone (AHL) acylase PvdQ	768
646770861	389	37.56	1	389	1	350	3.0e-76	279	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
646770863	209	41.67	17	207	27	217	9.0e-42	163	COG4318	Uncharacterized protein	221
646770865	289	24.62	32	288	7	265	1.0e-30	127	COG2116	Formate/nitrite transporter FocA, FNT family	265
646770869	165	55.28	5	165	4	164	6.0e-41	160	COG3685	Ferritin-like metal-binding protein YciE	167
646770875	763	56.93	431	762	1	330	9.0e-122	431	COG0620	Methionine synthase II (cobalamin-independent)	330
646770877	203	28.11	22	196	13	197	4.0e-10	58.2	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
646770879	331	36.56	7	317	1	314	1.0e-57	216	COG0451	Nucleoside-diphosphate-sugar epimerase	314
646770881	379	26.24	12	350	1	331	1.0e-36	147	COG0859	ADP-heptose:LPS heptosyltransferase	334
646770882	362	22.84	33	362	50	399	9.0e-19	88.1	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
646770883	581	42.4	1	578	1	555	0.0e+00	536	COG2192	Predicted carbamoyl transferase, NodU family	555
646770884	413	28.12	30	379	1	329	2.0e-37	150	COG0859	ADP-heptose:LPS heptosyltransferase	334
646770885	200	37.18	1	155	3	151	1.0e-36	146	COG0241	Histidinol phosphatase or a related phosphatase	181
646770886	435	28.22	1	407	1	379	4.0e-41	162	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
646770887	897	48.8	89	586	1	496	0.0e+00	519	COG5265	ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components	497
646770888	310	25.41	8	288	3	302	4.0e-24	105	COG1216	Glycosyltransferase, GT2 family	305
646770889	235	25.75	1	221	7	216	2.0e-09	56.2	COG2120	N-acetylglucosaminyl deacetylase, LmbE family	237
646770891	428	24.76	189	392	49	222	5.0e-18	86.1	COG0688	Phosphatidylserine decarboxylase	239
646770892	1360	40.37	223	488	1	268	2.0e-69	258	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
646770894	1039	35.21	219	480	4	268	7.0e-60	226	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
646770895	359	22.11	6	343	2	380	2.0e-24	106	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
646770899	286	41.15	27	279	4	256	5.0e-64	237	COG0171	NH3-dependent NAD+ synthetase	268
646770900	174	38.55	1	166	7	162	2.0e-34	138	COG1546	Nicotinamide mononucleotide (NMN) deamidase PncC	162
646770901	689	33.87	243	671	1	404	1.0e-77	284	COG2312	Erythromycin esterase homolog	405
646770903	434	22.04	7	429	7	405	3.0e-27	116	COG0025	NhaP-type Na+/H+ or K+/H+ antiporter	429
646770904	138	43.97	3	137	2	142	2.0e-33	134	COG1764	Organic hydroperoxide reductase OsmC/OhrA	143
646770905	244	18.29	9	244	28	273	1.0e-09	57	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
646770906	297	23.91	71	297	2	227	2.0e-15	76.7	COG1802	DNA-binding transcriptional regulator, GntR family	230
646770910	421	23.06	1	409	4	414	4.0e-20	92.9	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
646770911	362	53.64	2	361	1	370	4.0e-126	444	COG0562	UDP-galactopyranose mutase	374
646770914	326	26.07	2	212	1	209	2.0e-15	76.7	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
646770915	429	21.58	17	419	25	435	8.0e-28	118	COG2271	Sugar phosphate permease	448
646770916	442	17.11	22	356	24	358	3.0e-16	79.9	COG2271	Sugar phosphate permease	448
646770917	429	30.6	11	401	2	370	5.0e-56	212	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
646770918	234	32.9	4	232	2	230	1.0e-33	136	COG1802	DNA-binding transcriptional regulator, GntR family	230
646770921	337	32.16	5	335	3	341	5.0e-54	205	COG0673	Predicted dehydrogenase	342
646770922	554	29.6	10	499	1	492	4.0e-65	242	COG0366	Glycosidase	505
646770923	528	40.43	10	495	1	498	7.0e-95	341	COG0366	Glycosidase	505
646770925	297	24.67	1	281	1	294	2.0e-29	123	COG0451	Nucleoside-diphosphate-sugar epimerase	314
646770927	290	28.23	1	290	10	256	4.0e-26	112	COG3568	Metal-dependent hydrolase, endonuclease/exonuclease/phosphatase family	259
646770932	333	36.53	1	330	1	245	1.0e-58	220	COG4422	Bacteriophage protein gp37	250
646770936	307	37.97	3	265	14	272	1.0e-41	163	COG5377	Phage-related protein, predicted endonuclease	319
646770940	401	26.76	86	383	1	295	6.0e-28	118	COG0583	DNA-binding transcriptional regulator, LysR family	297
646770941	68	39.13	1	68	5	73	7.0e-12	62.3	COG0759	Membrane-anchored protein YidD, putatitve component of membrane protein insertase Oxa1/YidC/SpoIIIJ	92
646770957	439	23.37	178	436	1	286	4.0e-32	132	COG0863	DNA modification methylase	302
646770959	514	67.21	24	328	10	303	7.0e-98	351	COG5410	Uncharacterized protein	305
646770960	471	41.27	12	458	2	451	4.0e-92	332	COG3567	Uncharacterized protein	452
646770962	402	36.63	8	378	4	372	7.0e-60	224	COG3566	Uncharacterized protein	379
646770964	319	42.86	3	317	7	334	2.0e-68	253	COG4834	Uncharacterized protein	334
646770979	381	18.78	1	376	1	353	5.0e-32	132	COG3299	Uncharacterized phage protein gp47/JayE	353
646770989	133	28.23	3	125	6	127	3.0e-12	64.2	COG4308	Limonene-1,2-epoxide hydrolase	130
646770990	323	36.59	2	308	1	317	7.0e-47	181	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
646770991	252	42.86	8	251	3	251	3.0e-37	148	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
646770992	323	32.89	3	301	2	297	3.0e-32	132	COG0583	DNA-binding transcriptional regulator, LysR family	297
646770995	319	26.26	143	319	44	202	1.0e-10	60.8	COG2135	Putative SOS response-associated peptidase YedK	226
646770997	421	25	110	350	19	252	7.0e-08	52.2	COG4973	Site-specific recombinase XerC	299
646770998	261	47.1	1	259	1	253	3.0e-57	215	COG4705	Uncharacterized membrane-anchored protein	258
646771001	214	24.23	25	211	13	203	1.0e-13	70.4	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
646771004	756	35.32	522	753	31	264	9.0e-42	165	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
646771008	242	48.54	40	242	35	226	2.0e-61	229	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
646771009	373	21.83	13	364	16	380	8.0e-26	111	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
646771013	753	34.89	522	753	31	264	1.0e-41	165	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
646771016	717	21.85	12	717	24	719	1.0e-34	141	COG4773	Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid	719
646771018	336	35.05	26	333	6	315	2.0e-44	173	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
646771019	369	26.69	23	345	3	316	2.0e-37	149	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
646771020	208	31.28	13	201	8	201	3.0e-41	161	COG1573	Uracil-DNA glycosylase	202
646771022	466	20.32	12	444	13	389	2.0e-15	77.6	COG2814	Predicted arabinose efflux permease, MFS family	394
646771023	321	33.02	10	312	5	316	3.0e-38	152	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
646771024	275	45.19	1	269	1	268	1.0e-81	296	COG1464	ABC-type metal ion transport system, periplasmic component/surface antigen	268
646771026	429	27.61	20	282	2	231	1.0e-24	107	COG2041	Periplasmic DMSO/TMAO reductase YedYZ, molybdopterin-dependent catalytic subunit	271
646771028	146	34.91	38	142	20	125	6.0e-12	63.4	COG1846	DNA-binding transcriptional regulator, MarR family	126
646771029	631	21.96	29	402	1	342	4.0e-33	136	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
646771031	611	27.71	1	602	11	558	6.0e-76	278	COG4166	ABC-type oligopeptide transport system, periplasmic component	562
646771033	441	18.1	11	424	11	425	1.0e-18	88.3	COG2271	Sugar phosphate permease	448
646771034	319	19.74	28	253	19	241	5.0e-16	78.7	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
646771036	561	24.8	25	399	2	376	2.0e-54	207	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
646771038	275	31.33	1	274	1	326	7.0e-32	131	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
646771039	373	53.11	68	371	49	352	1.0e-111	396	COG4257	Streptogramin lyase	353
646771040	139	64.03	1	139	2	140	3.0e-45	173	COG5579	Uncharacterized protein, DUF1810 family	143
646771042	221	37.74	2	207	15	223	8.0e-32	130	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
646771043	399	36.62	19	398	14	396	1.0e-58	220	COG3213	Uncharacterized protein involved in response to NO	396
646771044	156	38.36	10	154	6	150	9.0e-29	119	COG4290	Guanyl-specific ribonuclease Sa	152
646771045	449	35.91	1	438	3	405	1.0e-92	334	COG1252	NADH dehydrogenase, FAD-containing subunit	405
646771047	366	40.66	1	356	1	351	3.0e-92	332	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
646771048	196	33.67	1	192	3	201	3.0e-12	65.3	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
646771049	296	30.64	5	285	1	295	4.0e-26	112	COG0583	DNA-binding transcriptional regulator, LysR family	297
646771050	296	32.78	3	296	2	295	3.0e-37	148	COG0583	DNA-binding transcriptional regulator, LysR family	297
646771051	231	31.75	4	206	3	212	1.0e-32	133	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
646771053	249	31.44	1	209	6	231	9.0e-37	147	COG0300	Short-chain dehydrogenase	265
646771054	305	32.23	178	298	2	122	6.0e-21	94.9	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
646771055	547	39.02	4	536	6	532	1.0e-110	393	COG1283	Na+/phosphate symporter	533
646771056	266	28.36	1	266	2	266	8.0e-30	124	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
646771057	294	32.86	10	289	2	272	3.0e-33	135	COG0555	ABC-type sulfate transport system, permease component	274
646771058	391	40.66	25	386	2	352	1.0e-99	356	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
646771059	343	26.73	47	340	2	292	9.0e-36	144	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
646771060	482	43.49	13	481	2	469	3.0e-118	419	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
646771061	423	21.05	16	417	34	440	4.0e-31	129	COG1524	Predicted pyrophosphatase or phosphodiesterase, AlkP superfamily	450
646771062	385	32.7	17	383	6	372	3.0e-86	312	COG0075	Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism protein PucG	383
646771064	273	39.29	20	270	2	253	4.0e-59	221	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
646771065	306	33.99	1	253	1	253	1.0e-54	207	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
646771066	832	38.29	426	817	1	370	9.0e-84	305	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
646771069	382	39.68	315	377	2	64	4.0e-06	46.1	COG2771	DNA-binding transcriptional regulator, CsgD family	65
646771070	503	27.43	33	500	10	457	1.0e-75	277	COG0076	Glutamate or tyrosine decarboxylase or a related PLP-dependent protein	460
646771072	315	63.25	8	309	9	310	5.0e-108	384	COG2313	Pseudouridine-5'-phosphate glycosidase (pseudoU degradation)	310
646771073	220	26	49	194	13	143	4.0e-15	75.4	COG0262	Dihydrofolate reductase	167
646771075	375	27.25	25	371	29	361	1.0e-56	213	COG0075	Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism protein PucG	383
646771076	369	42.39	1	361	3	357	6.0e-91	327	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
646771077	294	36.08	10	293	9	292	3.0e-37	148	COG0583	DNA-binding transcriptional regulator, LysR family	297
646771078	112	74.11	1	112	1	112	6.0e-40	155	COG0347	Nitrogen regulatory protein PII	112
646771079	470	58.44	67	467	1	399	1.0e-122	433	COG0004	Ammonia channel protein AmtB	409
646771082	646	42.12	2	641	1	605	0.0e+00	521	COG3284	Transcriptional regulator of acetoin/glycerol metabolism	606
646771083	351	21.08	5	335	2	334	3.0e-22	99.6	COG3199	Predicted polyphosphate- or ATP-dependent NAD kinase	355
646771084	327	46.36	1	327	18	346	6.0e-102	364	COG1071	TPP-dependent pyruvate or acetoin dehydrogenase subunit alpha	358
646771085	334	57.1	4	332	1	321	1.0e-130	459	COG0022	Pyruvate/2-oxoglutarate/acetoin dehydrogenase complex, dehydrogenase (E1) component	324
646771086	369	27.8	115	368	5	279	4.0e-25	109	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
646771087	326	58.53	19	317	2	298	4.0e-122	431	COG0320	Lipoate synthase	306
646771089	306	24.68	1	306	1	297	1.0e-24	107	COG0583	DNA-binding transcriptional regulator, LysR family	297
646771090	431	41.81	1	407	4	400	4.0e-86	312	COG1301	Na+/H+-dicarboxylate symporter	415
646771091	488	30.64	250	483	3	227	2.0e-47	184	COG1794	Aspartate/glutamate racemase	230
646771092	472	62.96	7	465	5	463	0.0e+00	693	COG1027	Aspartate ammonia-lyase	471
646771093	373	41.39	46	371	19	348	1.0e-81	296	COG0252	L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D	351
646771094	868	32.25	389	725	2	329	1.0e-41	165	COG0642	Signal transduction histidine kinase	336
646771096	742	25.13	21	582	21	545	2.0e-51	198	COG0659	Sulfate permease or related transporter, MFS superfamily	554
646771100	517	31.81	68	503	11	445	5.0e-45	176	COG1538	Outer membrane protein TolC	457
646771101	1081	29.28	33	1061	1	1008	0.0e+00	745	COG0841	Multidrug efflux pump subunit AcrB	1009
646771102	368	30.25	1	356	6	366	4.0e-21	96	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
646771103	556	32.97	22	554	29	532	1.0e-81	297	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
646771107	360	27.53	3	272	1	285	5.0e-25	108	COG3320	Thioester reductase domain of alpha aminoadipate reductase Lys2 and NRPSs	382
646771110	257	28.11	49	229	58	229	5.0e-11	61.9	COG5031	Ubiquinone biosynthesis protein Coq4	235
646771111	369	20.92	37	337	4	280	4.0e-08	53	COG1907	Predicted archaeal sugar kinase	312
646771112	510	26.58	16	390	28	408	2.0e-33	137	COG1032	Radical SAM superfamily enzyme YgiQ, UPF0313 family	490
646771113	475	50.86	8	461	9	471	0.0e+00	573	COG3033	Tryptophanase	471
646771114	250	24.54	18	228	3	204	4.0e-20	91.9	COG0125	Thymidylate kinase	208
646771116	157	45.81	1	155	1	154	3.0e-28	117	COG1522	DNA-binding transcriptional regulator, Lrp family	154
646771117	357	53.76	1	357	10	361	3.0e-113	401	COG3185	4-hydroxyphenylpyruvate dioxygenase and related hemolysins	363
646771118	460	54.08	1	451	3	455	0.0e+00	523	COG1113	L-asparagine transporter and related permeases	462
646771119	401	52.27	1	396	1	396	0.0e+00	543	COG1448	Aspartate/tyrosine/aromatic aminotransferase	396
646771120	372	18.93	9	362	6	306	1.0e-25	111	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
646771122	321	29.47	1	297	1	297	9.0e-24	104	COG0583	DNA-binding transcriptional regulator, LysR family	297
646771123	469	21.61	1	460	6	414	6.0e-28	118	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
646771125	442	25.57	76	384	63	350	8.0e-10	58.7	COG2814	Predicted arabinose efflux permease, MFS family	394
646771126	269	22.89	28	228	8	201	1.0e-10	60.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
646771127	3579	19.76	2991	3579	17	577	4.0e-08	56.6	COG4625	Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain	577
646771128	441	55.97	14	437	15	435	0.0e+00	524	COG1541	Phenylacetate-coenzyme A ligase PaaK, adenylate-forming domain family	438
646771129	519	46.69	11	297	6	292	3.0e-83	302	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
646771130	400	39.56	1	400	1	392	6.0e-87	314	COG0183	Acetyl-CoA acetyltransferase	392
646771131	564	22.67	88	527	37	437	2.0e-29	124	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
646771132	362	29.59	5	298	4	266	3.0e-49	189	COG1018	Ferredoxin-NADP reductase	266
646771133	194	30.91	13	120	3	111	1.0e-17	83.4	COG2151	Metal-sulfur cluster biosynthetic enzyme	111
646771134	270	40.15	10	270	20	265	2.0e-56	212	COG3396	1,2-phenylacetyl-CoA epoxidase, catalytic subunit	265
646771135	94	61.17	2	94	7	109	4.0e-31	126	COG3460	1,2-phenylacetyl-CoA epoxidase, PaaB subunit	117
646771136	332	46.82	32	297	1	265	3.0e-90	325	COG3396	1,2-phenylacetyl-CoA epoxidase, catalytic subunit	265
646771137	329	36.78	3	329	2	326	2.0e-61	229	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
646771139	215	42.18	2	211	1	211	6.0e-50	190	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
646771140	563	41.32	38	363	4	337	1.0e-70	261	COG2187	Aminoglycoside phosphotransferase family enzyme	337
646771144	173	33.11	1	149	4	154	5.0e-14	70.8	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
646771145	225	54.03	4	214	3	213	3.0e-57	215	COG1926	Predicted phosphoribosyltransferase	220
646771148	573	24.04	6	571	13	552	3.0e-57	216	COG2831	Hemolysin activation/secretion protein	554
646771150	189	31.84	1	178	1	179	4.0e-24	104	COG3038	Cytochrome b561	181
646771151	176	38.15	5	174	4	176	7.0e-28	116	COG3038	Cytochrome b561	181
646771153	143	30.67	1	141	11	160	8.0e-08	49.7	COG2391	Uncharacterized membrane protein YedE/YeeE, contains two sulfur transport domains	198
646771154	267	28.79	1	264	7	254	7.0e-09	54.6	COG0730	Uncharacterized membrane protein YfcA	258
646771155	293	28.09	1	263	7	249	1.0e-26	113	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
646771156	471	37.73	39	464	123	556	8.0e-100	357	COG3829	Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding Fis domains	560
646771160	942	34.19	436	706	71	334	7.0e-40	159	COG0642	Signal transduction histidine kinase	336
646771161	377	21.05	35	352	1	314	9.0e-17	81.4	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
646771163	474	48.64	3	473	2	480	0.0e+00	506	COG5310	Homospermidine synthase	481
646771164	436	30.98	33	418	2	387	1.0e-52	200	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
646771166	147	33.08	14	146	15	143	6.0e-19	87	COG0071	Molecular chaperone IbpA, HSP20 family	146
646771167	135	33.62	20	132	30	145	5.0e-15	73.5	COG0071	Molecular chaperone IbpA, HSP20 family	146
646771168	186	34.48	48	185	1	145	1.0e-24	105	COG0071	Molecular chaperone IbpA, HSP20 family	146
646771172	402	36.36	1	402	1	350	1.0e-69	256	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
646771173	354	31.28	34	258	19	232	3.0e-38	152	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
646771174	875	48.31	35	564	2	534	0.0e+00	518	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
646771181	189	41.11	2	177	1	167	1.0e-38	152	COG0629	Single-stranded DNA-binding protein	167
646771196	752	27.98	319	724	135	488	2.0e-42	168	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
646771204	432	27.21	165	432	104	357	2.0e-20	94	COG2948	Type IV secretory pathway, VirB10 components	360
646771205	294	28.12	67	288	35	239	3.0e-20	92.4	COG3504	Type IV secretory pathway, VirB9 components	265
646771209	402	26.85	119	374	3	241	6.0e-32	132	COG1192	Cellulose biosynthesis protein BcsQ	259
646771210	327	31.22	57	259	2	203	3.0e-20	92.7	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
646771215	464	44.01	26	451	4	430	3.0e-127	448	COG3486	Lysine/ornithine N-monooxygenase	436
646771216	417	18.23	1	383	11	384	2.0e-07	51	COG2814	Predicted arabinose efflux permease, MFS family	394
646771218	624	34.33	11	604	1	598	0.0e+00	487	COG4264	Siderophore synthetase component	602
646771220	409	22.31	22	390	4	362	1.0e-36	147	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
646771226	2170	33.43	857	1515	1	642	1.0e-103	373	COG1020	Non-ribosomal peptide synthetase component F	642
646771227	450	26.88	3	437	12	450	1.0e-50	194	COG0534	Na+-driven multidrug efflux pump	455
646771230	341	29.23	6	328	3	303	5.0e-35	141	COG3547	Transposase	303
646771234	111	28.85	1	102	3	106	4.0e-13	66.5	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
646771236	368	25	15	162	16	156	3.0e-15	76.3	COG3666	Transposase	161
646771241	294	21.33	14	223	1	196	9.0e-19	87.5	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
646771243	252	29.15	1	244	5	250	7.0e-36	144	COG1484	DNA replication protein DnaC	254
646771244	506	30.74	26	266	3	246	3.0e-29	123	COG4584	Transposase	278
646771250	430	28.97	9	426	3	408	6.0e-62	231	COG2124	Cytochrome P450	411
646771251	455	28.9	5	455	46	512	4.0e-69	255	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component	526
646771252	447	30.82	1	444	3	467	4.0e-73	269	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
646771253	562	22.51	41	541	5	445	8.0e-23	102	COG1231	Monoamine oxidase	450
646771254	1015	39.17	2	1003	1	1006	0.0e+00	836	COG0841	Multidrug efflux pump subunit AcrB	1009
646771255	383	29.31	44	367	35	368	6.0e-27	115	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
646771256	530	35.7	80	516	17	451	9.0e-54	205	COG1538	Outer membrane protein TolC	457
646771257	198	48.96	7	198	1	192	3.0e-66	244	COG0529	Adenylylsulfate kinase or related kinase	197
646771258	581	29.55	1	552	1	553	8.0e-71	261	COG2192	Predicted carbamoyl transferase, NodU family	555
646771261	250	18.03	5	217	2	227	1.0e-06	47	COG4424	LPS sulfotransferase NodH	250
646771262	262	20.91	39	258	43	254	1.0e-06	47.5	COG1682	ABC-type polysaccharide/polyol phosphate export permease	263
646771263	304	44.63	5	300	4	293	2.0e-73	269	COG1131	ABC-type multidrug transport system, ATPase component	293
646771264	447	25.64	9	385	16	394	2.0e-45	177	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
646771265	225	35.12	20	219	64	257	3.0e-32	131	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
646771266	302	19.39	6	299	1	292	2.0e-23	102	COG0583	DNA-binding transcriptional regulator, LysR family	297
646771269	310	28.81	5	288	1	292	4.0e-28	118	COG0583	DNA-binding transcriptional regulator, LysR family	297
646771270	548	40.33	12	548	32	550	0.0e+00	470	COG3604	Transcriptional regulator containing GAF, AAA-type ATPase, and DNA-binding Fis domains	550
646771271	497	34.19	3	460	4	452	9.0e-91	327	COG2710	Nitrogenase molybdenum-iron protein, alpha and beta chains	456
646771272	453	31.54	7	436	23	447	2.0e-67	250	COG2710	Nitrogenase molybdenum-iron protein, alpha and beta chains	456
646771274	72	45.16	1	62	5	66	4.0e-08	49.7	COG5420	Uncharacterized protein	71
646771277	506	30.74	26	266	3	246	3.0e-29	123	COG4584	Transposase	278
646771278	252	29.15	1	244	5	250	7.0e-36	144	COG1484	DNA replication protein DnaC	254
646771285	100	47.31	8	100	8	99	3.0e-26	110	COG2440	Ferredoxin-like protein FixX	99
646771286	437	31.25	6	436	3	396	4.0e-68	252	COG0644	Dehydrogenase (flavoprotein)	396
646771287	372	46.2	31	359	2	313	8.0e-95	340	COG2025	Electron transfer flavoprotein, alpha subunit	313
646771288	282	47.58	1	246	1	238	4.0e-64	238	COG2086	Electron transfer flavoprotein, alpha and beta subunits	260
646771290	379	41.1	3	375	2	382	2.0e-85	309	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
646771291	532	20.36	69	345	6	256	6.0e-24	105	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
646771293	119	27.96	1	93	2	93	3.0e-10	57.5	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
646771295	72	57.14	1	70	1	69	1.0e-17	81.6	COG5554	Nitrogen fixation protein	69
646771297	387	35.42	1	379	1	374	1.0e-75	277	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
646771298	367	24.34	15	162	16	156	2.0e-14	73.6	COG3666	Transposase	161
646771304	293	69.34	4	276	1	273	5.0e-118	417	COG1348	Nitrogenase subunit NifH, an ATPase	278
646771305	487	35.9	25	485	1	449	1.0e-103	370	COG2710	Nitrogenase molybdenum-iron protein, alpha and beta chains	456
646771306	519	28.98	35	515	3	453	6.0e-86	311	COG2710	Nitrogenase molybdenum-iron protein, alpha and beta chains	456
646771307	212	35.32	8	212	4	213	9.0e-38	150	COG3047	Outer membrane protein W	213
646771308	298	45.2	18	267	8	247	7.0e-63	234	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
646771309	669	52.36	42	609	4	566	0.0e+00	578	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
646771310	203	40.3	4	203	12	209	4.0e-38	151	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
646771311	108	41.24	10	106	13	109	7.0e-16	75.7	COG3125	Heme/copper-type cytochrome/quinol oxidase, subunit 4	111
646771315	210	43.81	2	209	1	210	3.0e-49	188	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
646771318	331	40.37	1	318	1	315	2.0e-82	299	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
646771319	387	40.77	6	387	3	390	2.0e-90	326	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
646771321	360	20.99	1	330	1	324	8.0e-09	54.9	COG0686	Alanine dehydrogenase	371
646771322	330	28.74	63	319	1	227	1.0e-26	114	COG3039	Transposase and inactivated derivatives, IS5 family	230
646771324	342	36.92	1	279	1	268	2.0e-36	147	COG4584	Transposase	278
646771325	530	28.55	5	500	5	523	2.0e-59	223	COG0578	Glycerol-3-phosphate dehydrogenase	532
646771326	295	35.04	54	287	15	230	6.0e-20	91.6	COG2801	Transposase InsO and inactivated derivatives	232
646771328	442	23.08	80	428	63	388	1.0e-09	58.3	COG2814	Predicted arabinose efflux permease, MFS family	394
646771329	473	25	13	434	9	389	3.0e-49	189	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
646771330	383	22.39	2	383	1	354	2.0e-35	143	COG3203	Outer membrane protein (porin)	354
646771331	429	27.63	13	427	1	381	2.0e-46	180	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
646771332	430	19.49	78	428	63	389	5.0e-06	46.4	COG2814	Predicted arabinose efflux permease, MFS family	394
646771333	441	25.32	29	420	8	336	9.0e-47	181	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
646771334	166	29.56	3	158	2	159	9.0e-27	113	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
646771335	305	25.58	1	296	1	297	5.0e-33	135	COG0583	DNA-binding transcriptional regulator, LysR family	297
646771337	122	36.08	24	120	20	114	9.0e-14	68.8	COG3450	Predicted enzyme of the cupin superfamily	116
646771338	477	42.07	6	476	1	468	3.0e-124	439	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
646771339	300	35.56	41	264	32	239	1.0e-36	146	COG4849	Predicted nucleotidyltransferase	269
646771340	340	30.14	68	336	65	338	4.0e-28	119	COG4861	Uncharacterized protein	345
646771347	1047	20.93	442	1047	19	600	1.0e-14	76	COG3468	Type V secretory pathway, adhesin AidA	644
646771351	349	24.74	53	335	35	296	1.0e-07	51.1	COG3547	Transposase	303
646771352	98	31	1	98	1	99	1.0e-07	47.9	COG2963	Transposase and inactivated derivatives	116
646771353	333	35.09	20	297	13	292	3.0e-50	192	COG4782	Esterase/lipase superfamily enzyme	377
646771357	381	23.1	1	379	9	399	1.0e-31	131	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
646771358	428	19.81	76	382	63	347	4.0e-08	53.3	COG2814	Predicted arabinose efflux permease, MFS family	394
646771359	470	23.61	48	455	38	408	6.0e-28	119	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
646771360	309	28	7	304	4	297	4.0e-25	108	COG0583	DNA-binding transcriptional regulator, LysR family	297
646771361	384	23.35	1	384	1	354	3.0e-41	162	COG3203	Outer membrane protein (porin)	354
646771362	519	35.91	144	517	8	408	2.0e-40	160	COG0840	Methyl-accepting chemotaxis protein	408
646771363	416	62.01	1	406	4	407	0.0e+00	519	COG3844	Kynureninase	407
646771365	337	35.04	213	329	8	122	9.0e-15	74.5	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
646771366	342	29.55	108	326	9	216	5.0e-36	145	COG0543	NAD(P)H-flavin reductase	252
646771367	162	45.06	1	162	3	164	4.0e-42	163	COG5517	3-phenylpropionate/cinnamic acid dioxygenase, small subunit	164
646771368	463	22.9	28	454	4	362	2.0e-48	187	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
646771369	336	28.17	6	326	3	301	1.0e-32	133	COG3547	Transposase	303
646771371	1808	34.31	301	1145	2	849	0.0e+00	472	COG3899	Predicted ATPase	849
646771373	341	29.63	5	324	1	301	2.0e-28	120	COG3547	Transposase	303
646771374	197	37.66	40	115	24	100	4.0e-13	68.1	COG1605	Chorismate mutase	101
646771377	252	29.15	1	244	5	250	7.0e-36	144	COG1484	DNA replication protein DnaC	254
646771378	506	30.74	26	266	3	246	3.0e-29	123	COG4584	Transposase	278
646771379	400	24.73	38	390	29	331	2.0e-17	84.3	COG3866	Pectate lyase	345
646771380	389	26.73	65	367	28	301	9.0e-18	85	COG3547	Transposase	303
646771381	240	56.78	5	239	1	236	2.0e-86	312	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
646771382	263	56.92	9	260	1	250	3.0e-91	328	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
646771383	389	38.9	21	367	1	306	1.0e-53	204	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
646771384	316	43.81	1	315	3	297	3.0e-53	202	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
646771386	341	29.85	6	328	3	303	2.0e-36	146	COG3547	Transposase	303
646771387	268	29	7	102	2	101	5.0e-10	58.6	COG3293	Transposase	124
646771388	389	26.73	65	367	28	301	9.0e-18	85	COG3547	Transposase	303
646771391	252	29.56	42	244	21	213	5.0e-29	121	COG2091	Phosphopantetheinyl transferase	223
646771393	126	36.89	17	118	19	121	9.0e-19	85.7	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
646771396	663	48.43	349	662	26	342	4.0e-84	306	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
646771401	338	53.73	1	335	1	323	2.0e-114	405	COG2515	1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase, PLP-dependent ACC family	323
646771402	482	28.89	4	479	3	462	6.0e-60	225	COG4529	Uncharacterized NAD(P)/FAD-binding protein YdhS	474
646771404	389	33.19	109	343	8	224	3.0e-16	80	COG2801	Transposase InsO and inactivated derivatives	232
646771410	518	27.5	101	260	3	156	3.0e-13	70.1	COG3436	Transposase	157
646771411	324	28.34	67	310	1	219	7.0e-17	81.7	COG3039	Transposase and inactivated derivatives, IS5 family	230
646771412	246	34.23	1	244	1	250	2.0e-34	139	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
646771417	376	26.36	60	376	2	279	6.0e-34	138	COG3618	Predicted metal-dependent hydrolase, TIM-barrel fold	279
646771418	437	20.69	18	437	3	409	1.0e-14	74.9	COG2223	Nitrate/nitrite transporter NarK	417
646771419	424	39.4	8	403	4	396	2.0e-98	353	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
646771421	267	33.33	32	251	2	246	2.0e-36	145	COG1414	DNA-binding transcriptional regulator, IclR family	246
646771424	481	30.91	3	164	1	161	3.0e-24	107	COG3666	Transposase	161
646771435	270	30.95	144	269	1	126	3.0e-21	96.1	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
646771438	227	38.81	1	219	1	208	8.0e-41	160	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
646771439	372	25	18	362	5	342	4.0e-26	112	COG0644	Dehydrogenase (flavoprotein)	396
646771442	300	23.24	28	291	38	309	7.0e-19	88.2	COG0226	ABC-type phosphate transport system, periplasmic component	318
646771443	562	33.46	139	408	63	328	2.0e-36	147	COG0642	Signal transduction histidine kinase	336
646771444	570	27.07	237	550	23	283	6.0e-22	99.5	COG4974	Site-specific recombinase XerD	300
646771452	416	36.69	1	416	4	396	1.0e-97	350	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
646771453	580	32	20	561	1	534	1.0e-106	380	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
646771454	443	18.38	45	409	38	385	5.0e-09	56	COG2814	Predicted arabinose efflux permease, MFS family	394
646771485	106	35.14	1	106	2	112	4.0e-16	76.2	COG2337	mRNA-degrading endonuclease, toxin component of the MazEF toxin-antitoxin module	112
646771486	82	44.44	1	61	1	61	8.0e-08	48.8	COG2336	Antitoxin component of the MazEF toxin-antitoxin module	82
646771491	85	42.5	4	75	10	88	9.0e-07	45.2	COG5572	Uncharacterized membrane protein	104
646771493	124	32.5	7	124	6	125	5.0e-17	80	COG2372	Copper-binding protein CopC (methionine-rich)	127
646771496	209	38.42	9	209	7	206	1.0e-37	150	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
646771497	219	28.83	73	182	13	122	2.0e-10	59.9	COG0526	Thiol-disulfide isomerase or thioredoxin	127
646771498	274	43.48	68	179	20	133	3.0e-24	105	COG3474	Cytochrome c2	135
646771499	174	25	26	153	1	127	3.0e-11	61.8	COG0526	Thiol-disulfide isomerase or thioredoxin	127
646771501	552	28.7	9	552	1	450	3.0e-56	213	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
646771502	105	32.67	6	99	4	104	8.0e-10	55.6	COG0347	Nitrogen regulatory protein PII	112
646771506	619	36.79	24	616	3	566	2.0e-119	423	COG4232	Thiol:disulfide interchange protein	569
646771507	117	35.85	9	114	8	107	3.0e-10	57.4	COG5569	Periplasmic Cu and Ag efflux protein CusF	108
646771508	1068	50.77	1	1043	1	1025	0.0e+00	1243	COG3696	Cu/Ag efflux pump CusA	1027
646771509	513	28.12	108	397	41	356	9.0e-19	88.6	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
646771510	431	21.74	22	418	27	438	1.0e-15	77.9	COG1538	Outer membrane protein TolC	457
646771513	481	30.91	3	164	1	161	3.0e-24	107	COG3666	Transposase	161
646771520	472	20.33	1	400	1	379	4.0e-14	72.9	COG0420	DNA repair exonuclease SbcCD nuclease subunit	390
646771528	568	29.78	3	564	1	637	2.0e-73	270	COG0210	Superfamily I DNA or RNA helicase	655
646771534	623	18.37	19	591	13	519	2.0e-10	61.5	COG3505	Type IV secretory pathway, VirD4 component, TraG/TraD family ATPase	596
646771538	820	24.29	2	765	8	733	9.0e-70	258	COG3451	Type IV secretory pathway, VirB4 component	796
646771539	87	28.99	1	65	25	93	1.0e-05	41.1	COG5268	Type IV secretory pathway, TrbD component	93
646771541	348	37.8	20	348	40	347	3.0e-59	222	COG4962	Pilus assembly protein, ATPase of CpaF family	355
646771545	423	20.37	5	420	15	388	2.0e-23	103	COG3864	Predicted metal-dependent peptidase	396
646771555	153	34.44	4	153	6	154	2.0e-18	85.4	COG3133	Outer membrane lipoprotein SlyB	154
646771565	558	32.83	1	195	2	191	1.0e-20	95	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
646771576	286	34.29	1	280	1	245	3.0e-42	165	COG4422	Bacteriophage protein gp37	250
648021327	377	25.89	10	120	8	112	1.0e-05	44.9	COG3415	Transposase	138
648021333	209	24.28	20	190	10	176	1.0e-05	43.8	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
648021339	433	26.13	53	375	51	362	2.0e-25	110	COG0045	Succinyl-CoA synthetase, beta subunit	387
648021354	201	27.8	8	174	56	251	6.0e-13	67.6	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
648021376	377	25.89	10	120	8	112	1.0e-05	44.9	COG3415	Transposase	138
648022544	66	30.88	1	65	4	71	3.0e-07	46.9	COG2608	Copper chaperone CopZ	71
648022570	224	29.59	2	97	27	124	8.0e-08	50.9	COG3293	Transposase	124
648022573	550	28.98	231	511	48	323	9.0e-34	138	COG4644	Transposase and inactivated derivatives, TnpA family	323
648022599	335	29.8	171	308	7	154	5.0e-09	55.4	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
648022607	191	44.68	4	187	3	189	1.0e-26	113	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
648022620	543	26.4	14	263	1	244	4.0e-35	143	COG1414	DNA-binding transcriptional regulator, IclR family	246
648022628	115	37.93	30	115	30	114	3.0e-11	60.4	COG2863	Cytochrome c553	121
648022629	435	19.19	32	395	1	345	5.0e-22	99.2	COG0446	NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase	415
648022711	453	37.89	198	451	91	315	8.0e-55	208	COG2826	Transposase and inactivated derivatives, IS30 family	318
648022722	498	26.36	17	266	21	265	4.0e-16	80.1	COG4584	Transposase	278
648022735	518	35.06	101	253	8	157	1.0e-17	84.7	COG3436	Transposase	157
648022742	194	24.49	13	181	5	200	3.0e-11	61.9	COG0778	Nitroreductase	207
648022746	322	29.96	1	263	11	269	2.0e-52	200	COG3267	Type II secretory pathway, component ExeA (predicted ATPase)	269
648022747	154	50.64	1	147	2	157	2.0e-27	115	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
648022755	333	31.4	13	295	8	281	2.0e-36	146	COG4974	Site-specific recombinase XerD	300
648022777	371	14.06	155	334	1	190	1.0e-06	48.2	COG3039	Transposase and inactivated derivatives, IS5 family	230
648022781	266	31.58	6	119	6	116	3.0e-09	55.9	COG3293	Transposase	124
648024254	472	24.08	156	451	18	283	4.0e-19	89.9	COG4974	Site-specific recombinase XerD	300
648024268	179	29.93	50	176	19	152	2.0e-11	61.9	COG3772	Phage-related lysozyme (muramidase), GH24 family	152
648024289	1833	36.9	295	1139	2	849	0.0e+00	503	COG3899	Predicted ATPase	849
