gene_oid	gene_length	percent_identity	query_start	query_end	subj_start	subj_end	evalue	bit_score	cog_id	cog_name	cog_length
2919289632	318	99.05	1	315	1	312	6.3e-86	282.2	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
2919289633	395	96.28	1	393	14	401	0.0e+00	466.2	COG3135	Predicted benzoate:H+ symporter BenE	402
2919289634	622	98.56	1	622	10	627	0.0e+00	835.5	COG3158	K+ transporter	627
2919289637	488	97.28	2	488	4	503	4.6e-103	339.7	COG0168	Trk-type K+ transport system, membrane component	499
2919289638	487	97.32	241	483	2	219	3.8e-90	105.8	COG0569	Trk K+ transport system, NAD-binding component	225
2919289638	487	98.21	1	233	1	220	3.8e-90	191	COG0569	Trk K+ transport system, NAD-binding component	225
2919289639	403	95.2	1	403	20	416	0.0e+00	545.5	COG0014	Gamma-glutamyl phosphate reductase	417
2919289641	457	97.42	45	438	3	380	8.9e-51	167.4	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2919289642	351	96.41	4	346	5	326	1.5e-73	241.9	COG1466	DNA polymerase III, delta subunit	334
2919289643	325	91.26	3	313	25	306	1.4e-73	241.8	COG0010	Arginase family enzyme	305
2919289644	165	87.85	1	165	6	164	6.8e-29	95	COG2980	Outer membrane lipoprotein LptE/RlpB (LPS assembly)	178
2919289645	897	100	1	897	1	823	0.0e+00	980.9	COG0495	Leucyl-tRNA synthetase	814
2919289646	150	92.81	1	139	9	137	1.1e-38	126.6	COG0848	Biopolymer transport protein ExbD	137
2919289647	262	95.83	6	219	3	209	2.8e-49	162.2	COG0811	Biopolymer transport protein ExbB/TolQ	216
2919289648	279	99.25	13	278	3	267	3.4e-102	335.6	COG0289	Dihydrodipicolinate reductase	266
2919289649	187	78	7	145	15	131	1.7e-26	86.9	COG2913	Outer membrane protein assembly factor BamE, lipoprotein component of the BamABCDE complex	147
2919289650	139	92.41	1	139	9	142	3.2e-47	154.3	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
2919289651	318	96.75	5	317	7	304	1.5e-93	307.5	COG1493	Serine kinase of the HPr protein, regulates carbohydrate metabolism	308
2919289652	155	97.37	3	152	3	150	3.8e-34	111.8	COG1762	Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type)	152
2919289653	111	94.55	1	111	1	104	2.0e-36	119	COG1544	Ribosome-associated translation inhibitor RaiA	110
2919289654	409	96.71	3	400	4	385	1.3e-67	222.1	COG2814	Predicted arabinose efflux permease, MFS family	394
2919289655	307	98.18	11	306	5	274	5.6e-91	298.6	COG0152	Phosphoribosylaminoimidazole-succinocarboxamide synthase	247
2919289656	245	60.38	2	123	45	140	8.2e-19	61.5	COG3126	Uncharacterized lipoprotein YbaY	158
2919289657	302	91.15	1	301	26	303	1.9e-77	253.2	COG3118	Negative regulator of GroEL, contains thioredoxin-like and TPR-like domains	304
2919289658	164	92.07	1	161	5	155	1.8e-71	233.1	COG0041	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase	162
2919289659	390	95.74	12	387	2	361	1.4e-125	413.2	COG0026	Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)	375
2919289660	338	93.4	2	219	13	210	3.7e-65	210.6	COG0009	tRNA A37 threonylcarbamoyladenosine synthetase subunit TsaC/SUA5/YrdC	211
2919289661	317	16	6	84	11	70	2.3e-25	6.8	COG3240	Phospholipase/lecithinase/hemolysin	370
2919289661	317	65.07	60	317	97	340	2.3e-25	80.8	COG3240	Phospholipase/lecithinase/hemolysin	370
2919289662	228	97.71	8	228	6	218	6.3e-49	160.7	COG3047	Outer membrane protein W	213
2919289663	380	88	10	377	6	335	4.5e-21	66.1	COG3240	Phospholipase/lecithinase/hemolysin	370
2919289664	432	70.17	116	391	45	251	1.2e-06	22.2	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2919289665	89	91.92	1	87	5	95	4.8e-19	62.8	COG4095	Uncharacterized conserved protein, contains PQ loop repeat	89
2919289666	491	94.96	18	491	19	470	3.3e-93	307.2	COG2027	D-alanyl-D-alanine carboxypeptidase	470
2919289667	326	97.34	3	323	5	297	5.0e-30	98.9	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2919289668	237	99.1	1	223	1	219	4.0e-41	135.5	COG1214	tRNA A37 threonylcarbamoyladenosine modification protein TsaB	220
2919289669	166	89.95	17	166	16	185	1.9e-26	87.3	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
2919289671	328	95.12	4	327	17	328	3.5e-66	217.3	COG0598	Mg2+ and Co2+ transporter CorA	322
2919289672	250	98.73	1	250	3	236	1.2e-58	192.5	COG0775	Nucleoside phosphorylase	234
2919289673	559	97.36	14	559	5	557	0.0e+00	453.4	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2919289674	473	100	1	471	1	470	0.0e+00	715.7	COG1282	NAD/NADP transhydrogenase beta subunit	463
2919289675	534	31.68	411	534	87	201	0.0e+00	68.7	COG3288	NAD/NADP transhydrogenase alpha subunit	356
2919289675	534	99.72	11	376	1	362	0.0e+00	499.5	COG3288	NAD/NADP transhydrogenase alpha subunit	356
2919289677	354	99.65	1	329	1	287	7.9e-108	354.2	COG0191	Fructose/tagatose bisphosphate aldolase	286
2919289678	463	68.02	36	401	57	324	3.6e-34	111.1	COG0642	Signal transduction histidine kinase	336
2919289679	234	99.14	1	232	1	230	2.7e-73	238.4	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2919289680	218	67.47	2	199	61	228	3.2e-38	125.7	COG3907	Membrane-associated enzyme, PAP2 (acid phosphatase) superfamily	249
2919289681	187	60.34	4	181	76	215	1.6e-18	61.8	COG0671	Membrane-associated phospholipid phosphatase	232
2919289682	480	98.95	3	479	3	475	0.0e+00	578.6	COG0469	Pyruvate kinase	477
2919289684	465	94.36	10	460	22	389	4.7e-89	290.6	COG0006	Xaa-Pro aminopeptidase	384
2919289685	258	61.38	7	257	4	235	5.4e-39	128.1	COG1208	NDP-sugar pyrophosphorylase, includes eIF-2Bgamma, eIF-2Bepsilon, and LPS biosynthesis proteins	358
2919289686	129	81.02	1	128	15	125	7.1e-24	78.4	COG1586	S-adenosylmethionine decarboxylase or arginine decarboxylase	136
2919289687	693	98.94	2	681	3	658	0.0e+00	959.5	COG0021	Transketolase	663
2919289688	332	98.81	2	332	1	331	0.0e+00	478.8	COG0057	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase	335
2919289689	367	83.92	26	366	40	326	2.3e-51	168.6	COG0668	Small-conductance mechanosensitive channel	316
2919289690	125	21.21	65	124	21	76	1.5e-03	9.3	COG1729	Periplasmic TolA-binding protein (function unknown)	262
2919289690	125	26.89	2	75	3	73	1.5e-03	7.5	COG1729	Periplasmic TolA-binding protein (function unknown)	262
2919289691	306	83.92	14	299	31	197	4.8e-51	165.6	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
2919289692	339	98.12	1	318	1	314	3.5e-98	322.6	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
2919289693	202	93	1	192	12	197	7.3e-30	98.4	COG4430	Uncharacterized conserved protein YdeI, YjbR/CyaY-like superfamily, DUF1801 family	200
2919289694	276	90.32	1	174	13	180	2.8e-26	86.2	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2919289695	117	14.89	6	116	296	380	2.8e-05	17.3	COG1293	Predicted component of the ribosome quality control (RQC) complex, YloA/Tae2 family, contains fibronectin-binding (FbpA) and DUF814 domains	564
2919289696	438	88.04	12	387	4	349	2.7e-50	165.9	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2919289697	199	89.5	3	199	18	196	1.7e-57	188.7	COG0740	ATP-dependent protease ClpP, protease subunit	200
2919289698	317	95.16	1	316	2	335	3.9e-52	171.8	COG0673	Predicted dehydrogenase	342
2919289701	309	97.86	20	303	4	277	2.3e-46	152.7	COG3618	Predicted metal-dependent hydrolase, TIM-barrel fold	279
2919289702	330	97.49	6	329	7	317	7.8e-78	255.9	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2919289703	227	95.28	6	219	8	209	4.1e-59	193.9	COG0684	Regulator of RNase E activity RraA	210
2919289704	344	69.08	12	336	56	265	3.2e-18	60	COG2159	Predicted metal-dependent hydrolase, TIM-barrel fold	293
2919289705	230	84.27	3	230	41	265	1.8e-23	77.3	COG0725	ABC-type molybdate transport system, periplasmic component	258
2919289706	321	98.34	1	318	1	296	1.6e-52	173.2	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919289707	304	94.76	4	279	2	272	1.1e-29	97.5	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
2919289708	326	97.81	4	325	6	317	2.5e-84	277.2	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2919289709	243	99.58	4	241	2	237	1.2e-84	277.3	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2919289710	257	99.21	5	251	2	253	2.6e-86	283.2	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2919289711	331	94.43	11	314	9	313	7.1e-65	213.3	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2919289712	290	97.67	1	290	5	298	2.7e-75	247.9	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2919289713	394	95.08	7	386	9	356	1.7e-47	156.2	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2919289714	258	93.53	8	246	9	225	9.0e-50	163.3	COG1802	DNA-binding transcriptional regulator, GntR family	230
2919289715	351	92.82	1	348	25	373	2.9e-75	248.1	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
2919289716	321	98.88	2	260	3	267	2.3e-65	214.7	COG1018	Ferredoxin-NADP reductase	266
2919289717	118	87.27	1	118	9	104	7.5e-07	23.8	COG1544	Ribosome-associated translation inhibitor RaiA	110
2919289718	673	91.39	364	617	13	235	1.2e-59	196	COG2114	Adenylate cyclase, class 3	227
2919289719	1189	32.31	438	536	91	174	1.3e-17	30	COG5010	Flp pilus assembly protein TadD, contains TPR repeats	257
2919289719	1189	56.92	297	456	52	199	1.3e-17	42.4	COG5010	Flp pilus assembly protein TadD, contains TPR repeats	257
2919289719	1189	61.06	14	272	54	260	1.4e-09	30.8	COG4254	Uncharacterized conserved protein, contains LysM and FecR  domains	339
2919289720	293	96.31	4	262	5	239	2.8e-54	178.3	COG2071	Gamma-glutamyl-gamma-aminobutyrate hydrolase PuuD (putrescine degradation), contains GATase1-like domain	243
2919289722	312	95.68	18	309	4	291	7.8e-46	151.3	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919289725	424	99.75	1	424	2	404	0.0e+00	561.2	COG4277	Predicted DNA-binding protein with the Helix-hairpin-helix motif	404
2919289727	333	89.08	19	230	1	155	1.1e-24	80.4	COG3576	Predicted flavin-nucleotide-binding protein, pyridoxine 5'-phosphate oxidase superfamily	173
2919289728	213	93.49	7	210	1	201	3.2e-45	148.7	COG0625	Glutathione S-transferase	211
2919289729	312	98.34	2	295	3	298	1.3e-68	226	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919289730	101	32.03	1	101	64	153	1.3e-01	6	COG4395	Predicted lipid-binding transport protein, Tim44 family	281
2919289731	158	91.53	3	158	2	163	5.5e-40	130.9	COG1047	FKBP-type peptidyl-prolyl cis-trans isomerase 2	174
2919289732	359	95	29	322	14	279	1.9e-70	231.5	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
2919289733	481	50.65	265	479	11	204	8.9e-42	23.4	COG0477	MFS family permease	338
2919289733	481	94.78	8	328	2	364	8.9e-42	114.8	COG0477	MFS family permease	338
2919289735	219	95.35	2	208	3	207	3.9e-41	135.4	COG0625	Glutathione S-transferase	211
2919289736	142	95.62	2	142	2	132	1.6e-37	122.8	COG2764	Uncharacterized conserved protein PhnB, glyoxalase superfamily	136
2919289737	221	89.95	8	221	11	198	3.9e-14	48.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2919289738	560	90.82	95	521	40	425	4.0e-102	337	COG0840	Methyl-accepting chemotaxis protein	408
2919289739	326	98.08	1	325	5	311	2.0e-47	155.7	COG2378	Predicted DNA-binding transcriptional regulator YafY, contains an HTH and WYL domains	311
2919289742	298	98.01	2	298	3	297	1.9e-65	215.8	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919289743	261	99.25	15	261	2	267	3.6e-70	230.8	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2919289744	265	98.88	18	264	3	267	2.2e-64	211.8	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2919289745	308	97.67	3	301	3	296	4.1e-71	234.2	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919289746	233	98.26	2	232	3	228	1.1e-51	170	COG1794	Aspartate/glutamate racemase	230
2919289747	326	81.45	1	312	24	282	1.2e-26	88.3	COG0657	Acetyl esterase/lipase	312
2919289749	254	98.71	6	245	2	230	1.0e-76	251.4	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2919289750	458	89.59	113	457	36	388	1.1e-53	177.6	COG0642	Signal transduction histidine kinase	336
2919289751	652	96.08	7	650	19	606	0.0e+00	563.8	COG3284	Transcriptional regulator of acetoin/glycerol metabolism	606
2919289752	507	99.37	20	502	2	477	0.0e+00	570.8	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2919289753	125	95.69	1	115	4	114	1.0e-45	148.6	COG3564	Uncharacterized conserved protein, DUF779 family	116
2919289754	656	91.76	171	640	36	425	6.3e-107	352.8	COG0840	Methyl-accepting chemotaxis protein	408
2919289755	146	80.89	1	146	13	139	1.4e-30	100.3	COG1607	Acyl-CoA hydrolase	157
2919289756	323	96.35	12	317	7	296	4.0e-47	155	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2919289757	330	38.18	9	245	44	169	2.5e-08	26.1	COG3608	Predicted deacylase	331
2919289758	324	97.18	6	324	8	317	1.0e-76	252.2	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2919289759	298	97.34	1	298	1	293	2.1e-45	150	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919289760	274	95	2	267	9	236	3.9e-52	171.1	COG0284	Orotidine-5'-phosphate decarboxylase	240
2919289761	185	65.13	42	183	26	124	1.8e-03	11.6	COG5616	TolB amino-terminal domain (function unknown)	152
2919289763	399	97.49	5	396	9	396	0.0e+00	479.4	COG0126	3-phosphoglycerate kinase	395
2919289764	111	90.65	4	108	8	104	9.8e-20	64.9	COG4392	Branched-chain amino acid transport protein	107
2919289765	274	92.05	5	242	11	230	1.6e-42	139.6	COG1296	Predicted branched-chain amino acid permease (azaleucine resistance)	238
2919289766	324	99.35	1	317	2	307	2.5e-109	359.4	COG0223	Methionyl-tRNA formyltransferase	307
2919289768	169	99.41	1	165	1	168	1.3e-63	207.6	COG0242	Peptide deformylase	168
2919289770	388	99.72	1	385	1	358	2.5e-113	372.8	COG0758	Predicted Rossmann fold nucleotide-binding protein DprA/Smf involved in DNA uptake	350
2919289772	316	98.05	1	305	2	303	2.2e-107	352.8	COG0341	Preprotein translocase subunit SecF	305
2919289773	627	99.43	75	611	3	522	0.0e+00	598.2	COG0342	Preprotein translocase subunit SecD	506
2919289774	90	89.69	1	90	7	93	1.4e-32	106.1	COG1862	Preprotein translocase subunit YajC	97
2919289775	1189	95.1	750	959	6	199	4.0e-31	101.6	COG1014	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, gamma subunit	203
2919289775	1189	99.07	26	732	2	639	0.0e+00	606.4	COG4231	TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit	640
2919289776	160	93.67	1	156	5	152	9.2e-39	127.2	COG1522	DNA-binding transcriptional regulator, Lrp family	154
2919289777	385	68.34	85	385	114	372	1.5e-84	278.4	COG2821	Membrane-bound lytic murein transglycosylase	373
2919289779	216	88.44	18	212	20	195	2.6e-44	145.9	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
2919289780	209	96.04	3	209	4	197	1.9e-68	224.1	COG4566	Two-component response regulator, FixJ family, consists of REC and HTH domains	202
2919289781	686	66.24	376	685	129	389	1.1e-52	174.4	COG0642	Signal transduction histidine kinase	336
2919289782	271	94.96	1	270	3	266	1.5e-69	228.2	COG0388	Predicted amidohydrolase	274
2919289783	1385	98.9	10	1368	12	1268	0.0e+00	690.1	COG3164	Uncharacterized conserved protein YhdP, contains DUF3971 and AsmA2 domains	1271
2919289784	921	93.77	17	921	54	956	0.0e+00	825	COG1391	Glutamine synthetase adenylyltransferase	963
2919289785	227	86.6	1	219	4	184	3.9e-22	73.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2919289786	460	97.39	14	460	3	450	2.2e-91	301.2	COG1538	Outer membrane protein TolC	457
2919289787	404	94.62	3	372	13	381	1.3e-48	160.1	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2919289788	1044	99.7	2	1006	1	1011	0.0e+00	993.8	COG0841	Multidrug efflux pump subunit AcrB	1009
2919289789	403	54.83	61	356	148	340	9.0e-11	35.3	COG2206	HD-GYP domain, c-di-GMP phosphodiesterase class II (or its inactivated variant)	344
2919289791	194	91.98	35	190	12	160	5.4e-55	179.2	COG0386	Glutathione peroxidase, house-cleaning role in reducing lipid peroxides	162
2919289792	436	93.96	1	436	9	428	0.0e+00	494.5	COG2907	Predicted NAD/FAD-binding protein	447
2919289793	267	90.8	7	266	11	247	3.7e-59	193.5	COG3496	Uncharacterized conserved protein, DUF1365 family	261
2919289794	420	98.95	132	419	4	286	2.7e-97	319.2	COG2230	Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases	283
2919289796	430	91.4	3	424	9	433	2.7e-44	143.5	COG2211	Na+/melibiose symporter or related transporter	467
2919289798	260	96.23	8	259	5	259	1.9e-38	126.2	COG0300	Short-chain dehydrogenase	265
2919289800	301	90.65	12	284	7	258	2.7e-33	109.6	COG1082	Sugar phosphate isomerase/epimerase	274
2919289801	299	73.28	3	283	10	275	3.7e-51	168.3	COG3185	4-hydroxyphenylpyruvate dioxygenase and related hemolysins	363
2919289802	302	95.77	19	299	6	277	8.7e-80	261.8	COG0169	Shikimate 5-dehydrogenase	283
2919289803	334	98.8	1	329	2	329	2.2e-114	376.3	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
2919289804	426	99.47	47	425	2	378	0.0e+00	459.5	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
2919289805	194	90.4	1	177	9	168	2.5e-41	135.2	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
2919289806	238	91.39	14	238	11	201	9.6e-22	72.8	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2919289807	204	94.42	1	204	1	203	5.4e-44	144.8	COG0625	Glutathione S-transferase	211
2919289808	459	99.32	12	459	1	436	3.2e-129	425.7	COG0015	Adenylosuccinate lyase	438
2919289809	563	50.54	265	548	102	287	3.1e-07	24.1	COG0457	Tetratricopeptide (TPR) repeat	291
2919289810	186	95.58	1	186	1	173	1.8e-55	181.4	COG4681	Uncharacterized conserved protein YaeQ, suppresses RfaH defect	181
2919289812	148	67.57	68	140	6	55	5.2e-18	58.8	COG3313	Predicted Fe-S protein YdhL, DUF1289 family	74
2919289813	251	80.86	1	215	8	214	1.3e-48	158.8	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
2919289815	117	95	1	117	2	115	9.3e-34	110.6	COG1950	Uncharacterized membrane protein YvlD, DUF360 family	120
2919289816	485	91.13	2	482	30	471	3.7e-88	290.5	COG4783	Putative Zn-dependent protease, contains TPR repeats	484
2919289818	171	98.72	4	165	2	155	1.4e-60	197.7	COG0315	Molybdenum cofactor biosynthesis enzyme	157
2919289820	164	79.86	2	142	3	113	1.9e-21	71.1	COG4968	Tfp pilus assembly protein PilE	139
2919289821	262	30.03	1	148	2	92	1.6e-17	36.9	COG1234	Ribonuclease BN, tRNA processing enzyme	292
2919289821	262	30.03	119	250	171	261	1.6e-17	18.7	COG1234	Ribonuclease BN, tRNA processing enzyme	292
2919289822	754	26.6	2	139	11	118	5.3e-49	71	COG4252	Extracellular (periplasmic) sensor domain CHASE2 (specificity unknown)	400
2919289822	754	59.85	205	465	156	398	5.3e-49	94.7	COG4252	Extracellular (periplasmic) sensor domain CHASE2 (specificity unknown)	400
2919289822	754	80.74	446	689	37	233	1.0e-52	172.4	COG2114	Adenylate cyclase, class 3	227
2919289823	231	10.9	192	230	136	158	2.6e-21	3.4	COG1716	Forkhead associated (FHA) domain, binds pSer, pThr, pTyr	191
2919289823	231	33.65	15	127	91	161	2.6e-21	64.9	COG1716	Forkhead associated (FHA) domain, binds pSer, pThr, pTyr	191
2919289824	262	94.49	1	257	7	263	6.7e-64	209.9	COG0631	Serine/threonine protein phosphatase PrpC	262
2919289825	848	88.18	1	409	41	398	2.3e-29	90.1	COG4252	Extracellular (periplasmic) sensor domain CHASE2 (specificity unknown)	400
2919289826	228	92.97	1	227	8	245	7.9e-48	155.8	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
2919289827	298	97.96	1	298	1	288	4.7e-118	387.9	COG0074	Succinyl-CoA synthetase, alpha subunit	293
2919289828	386	99.22	1	386	1	380	0.0e+00	527.7	COG0045	Succinyl-CoA synthetase, beta subunit	387
2919289829	316	96.28	1	315	2	337	3.6e-71	229.8	COG0002	N-acetyl-gamma-glutamylphosphate reductase	349
2919289830	152	84.88	5	152	21	166	1.5e-37	123.3	COG2137	SOS response regulatory protein OraA/RecX, interacts with RecA	174
2919289831	358	97.94	14	295	6	290	3.7e-128	420.6	COG0468	RecA/RadA recombinase	279
2919289832	173	69.92	36	157	16	108	4.0e-12	40.3	COG1846	DNA-binding transcriptional regulator, MarR family	126
2919289833	315	98.01	9	307	2	296	1.6e-64	212.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919289834	321	98.75	1	319	1	315	5.6e-87	285.9	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2919289835	306	93.75	23	305	7	261	1.1e-67	222.1	COG3741	N-formylglutamate amidohydrolase	272
2919289836	403	74.75	6	386	48	349	4.9e-37	122.2	COG1680	CubicO group peptidase, beta-lactamase class C family	390
2919289837	470	82.74	134	470	63	388	1.1e-50	167.7	COG0642	Signal transduction histidine kinase	336
2919289838	218	98.71	1	218	1	229	9.0e-65	212.4	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2919289839	224	99.14	1	222	1	230	2.8e-73	240.1	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2919289840	483	84.77	22	482	56	389	4.8e-59	194.9	COG0642	Signal transduction histidine kinase	336
2919289841	334	94.34	61	333	7	256	6.8e-57	186.7	COG2220	L-ascorbate metabolism protein UlaG, beta-lactamase superfamily	258
2919289844	284	98.74	28	279	2	237	2.3e-51	168.9	COG0340	Biotin-(acetyl-CoA carboxylase) ligase	238
2919289845	184	29.73	18	157	338	480	2.5e-34	112.5	COG2940	SET domain-containing protein (function unknown)	480
2919289846	979	98.43	3	652	1	566	0.0e+00	491.5	COG0550	DNA topoisomerase IA	570
2919289847	73	12.2	9	71	5	29	2.5e-03	11.8	COG3218	ABC-type uncharacterized transport system, auxiliary component	205
2919289849	327	97.05	16	323	8	270	7.7e-57	187	COG0584	Glycerophosphoryl diester phosphodiesterase	257
2919289850	250	98.8	10	244	2	248	1.6e-30	96.4	COG2365	Protein tyrosine/serine phosphatase	249
2919289851	445	53	24	268	8	210	1.3e-21	41.5	COG0477	MFS family permease	338
2919289851	445	53.52	247	442	6	210	1.3e-21	34.7	COG0477	MFS family permease	338
2919289852	198	78.92	6	196	19	164	1.7e-25	83.8	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
2919289853	126	96.58	1	122	3	143	3.4e-13	43	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2919289854	202	42.65	4	197	54	172	2.8e-05	18.7	COG0500	SAM-dependent methyltransferase	257
2919289855	249	93.94	8	240	3	219	9.5e-90	294.2	COG3148	Uncharacterized conserved protein YfiP, DTW domain	231
2919289856	159	66.05	6	150	50	156	8.3e-09	30.3	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2919289859	1023	36.03	663	1020	602	940	0.0e+00	586.8	COG0178	Excinuclease UvrABC ATPase subunit	935
2919289859	1023	64.29	21	644	3	607	0.0e+00	838.6	COG0178	Excinuclease UvrABC ATPase subunit	935
2919289860	1252	18.06	781	836	134	172	3.6e+00	4.5	COG3110	Uncharacterized conserved protein YccT, UPF0319 family	216
2919289860	1252	22.22	916	1024	123	170	3.6e+00	2.4	COG3110	Uncharacterized conserved protein YccT, UPF0319 family	216
2919289861	392	35.77	260	390	71	207	4.2e-27	14.3	COG0477	MFS family permease	338
2919289861	392	81.46	5	312	3	314	4.2e-27	75.2	COG0477	MFS family permease	338
2919289862	184	100	1	184	1	171	7.3e-54	177	COG0629	Single-stranded DNA-binding protein	167
2919289864	237	95.69	1	236	7	228	2.3e-30	99.9	COG0670	Integral membrane protein, interacts with FtsH	233
2919289865	389	99.16	4	371	2	355	0.0e+00	456.3	COG0482	tRNA U34 2-thiouridine synthase MnmA/TrmU, contains the PP-loop ATPase domain	356
2919289866	313	98.67	5	302	1	297	8.4e-64	210.4	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919289867	363	98.68	1	361	4	376	0.0e+00	435.3	COG2828	2-Methylaconitate cis-trans-isomerase PrpF (2-methyl citrate pathway)	378
2919289868	332	97.18	9	330	6	315	1.9e-85	280.8	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2919289869	354	98.61	1	354	6	360	1.0e-49	163.7	COG3203	Outer membrane protein (porin)	354
2919289870	277	99.25	13	273	2	267	4.5e-62	204.2	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2919289871	264	58.84	2	248	142	374	4.1e-30	98.9	COG0372	Citrate synthase	390
2919289872	508	96.13	3	507	15	560	4.4e-100	329.7	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2919289873	343	97.81	20	342	5	316	1.4e-97	320.8	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2919289874	275	95.93	32	270	2	237	7.5e-47	153.4	COG1414	DNA-binding transcriptional regulator, IclR family	246
2919289875	327	98.67	1	310	1	297	1.1e-54	180.4	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919289876	488	72.44	4	486	8	417	6.1e-34	109.7	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
2919289877	393	58.87	5	104	38	110	1.2e-03	12.1	COG1145	Ferredoxin	99
2919289878	331	97.81	8	330	6	317	2.9e-89	293.5	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2919289879	162	76.16	1	146	13	143	6.6e-13	43.2	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2919289880	166	70.37	1	150	14	146	5.3e-11	36.9	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
2919289881	234	95.61	1	207	1	196	5.2e-58	189.5	COG0307	Riboflavin synthase alpha chain	204
2919289883	410	13.5	18	175	28	59	1.1e-05	7.8	COG1122	Energy-coupling factor transporter ATP-binding protein EcfA2	235
2919289883	410	16.88	254	304	161	200	1.1e-05	9.1	COG1122	Energy-coupling factor transporter ATP-binding protein EcfA2	235
2919289885	449	97.09	13	436	13	412	0.0e+00	436.9	COG4222	Uncharacterized conserved protein	391
2919289886	83	12.31	2	80	33	96	2.7e-03	10.6	COG0815	Apolipoprotein N-acyltransferase	518
2919289887	572	59.69	58	399	6	276	3.5e-12	38.3	COG1231	Monoamine oxidase	450
2919289888	330	97.3	1	330	10	369	1.6e-112	362.1	COG3437	Response regulator c-di-GMP phosphodiesterase, RpfG family, contains REC and HD-GYP domains	360
2919289889	1250	65.99	509	885	132	391	3.2e-84	278	COG0642	Signal transduction histidine kinase	336
2919289889	1250	86.47	894	1225	5	119	1.5e-35	113.4	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2919289889	1250	96.19	12	254	5	231	1.2e-55	181.9	COG3300	MHYT domain, NO-binding membrane sensor	236
2919289890	524	98.03	21	519	10	507	0.0e+00	587.5	COG4262	Predicted spermidine synthase with an N-terminal membrane domain	508
2919289891	73	42.86	6	73	11	67	6.1e-09	30.1	COG3766	Uncharacterized membrane protein YjfL, UPF0719 family	133
2919289892	504	49.25	218	270	21	53	7.2e-05	9.7	COG2051	Ribosomal protein S27E	67
2919289892	504	58.21	1	46	13	51	7.2e-05	8.3	COG2051	Ribosomal protein S27E	67
2919289893	349	98.26	1	349	1	339	2.0e-99	326.8	COG4260	Membrane protease subunit, stomatin/prohibitin family, contains C-terminal Zn-ribbon domain	345
2919289894	90	87.5	15	86	2	64	6.2e-20	64.8	COG3205	Uncharacterized membrane protein	72
2919289896	101	6.99	1	55	5	37	3.9e-16	34.2	COG1749	Flagellar hook protein FlgE	423
2919289896	101	8.05	42	101	434	471	3.9e-16	20.9	COG1749	Flagellar hook protein FlgE	423
2919289897	326	98.34	31	326	1	296	3.6e-45	149.2	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919289898	453	96.87	16	453	10	442	0.0e+00	464	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
2919289899	209	46.15	1	203	43	192	2.4e-20	67.1	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
2919289900	505	99.37	11	491	2	477	0.0e+00	505.2	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2919289901	781	99.08	444	780	1	324	1.0e-108	356.8	COG0280	Phosphotransacetylase	327
2919289901	781	99.1	3	447	3	440	0.0e+00	574.2	COG0281	Malic enzyme	432
2919289902	113	67.76	2	113	48	150	7.6e-48	156.7	COG4290	Guanyl-specific ribonuclease Sa	152
2919289903	141	39.56	44	131	11	46	4.4e-06	20.5	COG2732	Barstar, RNAse (barnase) inhibitor	91
2919289905	259	96.92	2	259	4	255	2.9e-76	250.3	COG0030	16S rRNA A1518 and A1519 N6-dimethyltransferase RsmA/KsgA/DIM1 (may also have DNA glycosylase/AP lyase activity)	259
2919289906	477	45.23	332	474	172	318	8.9e-76	126	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
2919289906	477	79.08	56	333	15	271	8.9e-76	127.2	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
2919289907	805	93.84	5	801	41	787	2.6e-130	430.5	COG1452	LPS assembly outer membrane protein LptD (organic solvent tolerance protein OstA)	784
2919289908	384	94.59	26	377	13	344	2.1e-108	356.3	COG3178	Predicted phosphotransferase, aminoglycoside/choline kinase (APH/ChoK) family	351
2919289909	254	97.15	1	254	3	241	3.5e-62	203.9	COG1385	16S rRNA U1498 N3-methylase RsmE	246
2919289910	385	96.17	184	370	7	182	2.2e-52	171.5	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2919289912	429	99	1	407	1	395	5.6e-86	283.3	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2919289913	258	81.86	39	255	28	212	1.2e-30	100.2	COG2135	Putative SOS response-associated peptidase YedK	226
2919289914	419	97.54	24	397	2	358	1.4e-44	146.5	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2919289915	546	97.36	4	544	5	557	7.4e-109	358.7	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2919289916	495	99.38	1	495	1	480	0.0e+00	661.9	COG0043	3-polyprenyl-4-hydroxybenzoate decarboxylase	477
2919289917	198	97.38	6	194	3	188	1.1e-79	260.6	COG0163	3-polyprenyl-4-hydroxybenzoate decarboxylase	191
2919289918	137	82.96	1	128	14	125	1.0e-42	139.2	COG4273	Uncharacterized protein, contains metal-binding DGC domain	135
2919289919	172	83.33	7	168	8	147	2.8e-30	99.3	COG3154	Predicted lipid carrier protein YhbT, SCP2 domain	168
2919289920	206	89.32	1	206	23	231	5.9e-65	212.9	COG1272	Predicted membrane channel-forming protein YqfA, hemolysin III family	226
2919289921	320	85.14	3	313	2	299	2.3e-49	162.3	COG0826	Collagenase-like protease, PrtC family	347
2919289922	350	84.57	15	350	5	300	6.1e-99	325.4	COG0826	Collagenase-like protease, PrtC family	347
2919289923	394	95.7	1	392	13	390	5.4e-17	55.5	COG2814	Predicted arabinose efflux permease, MFS family	394
2919289924	308	98.34	6	300	3	298	1.6e-53	176.6	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919289925	456	94.74	60	437	12	407	2.6e-39	129.5	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
2919289926	180	79.33	14	177	20	138	2.0e-30	99.7	COG3753	Uncharacterized conserved protein YidB, DUF937 family	143
2919289929	290	94.48	9	287	12	302	4.1e-57	187.5	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
2919289930	175	46.67	3	152	22	119	4.9e-06	20.4	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
2919289931	496	98.56	15	488	5	416	1.1e-37	124.3	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
2919289932	408	94.54	174	384	10	182	1.3e-53	175.5	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2919289933	687	87.06	181	640	56	425	3.5e-114	376.7	COG0840	Methyl-accepting chemotaxis protein	408
2919289934	277	97.69	1	270	1	254	1.2e-91	300.9	COG3622	Hydroxypyruvate isomerase	260
2919289935	377	96.31	10	370	6	266	5.4e-80	262.9	COG0584	Glycerophosphoryl diester phosphodiesterase	257
2919289936	194	46.86	1	157	41	152	7.3e-13	41.6	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
2919289937	376	95.16	3	370	16	369	0.0e+00	472.1	COG2021	Homoserine acetyltransferase	368
2919289938	188	97.4	1	188	1	187	1.3e-65	214.9	COG2119	Putative Ca2+/H+ antiporter, TMEM165/GDT1 family	190
2919289940	125	27.66	2	99	121	211	1.1e-22	75	COG0724	 RNA recognition motif (RRM) domain	306
2919289942	260	97.74	1	256	5	263	6.2e-49	160.7	COG0300	Short-chain dehydrogenase	265
2919289943	206	92.51	3	202	9	181	9.7e-18	58.5	COG3117	Lipopolysaccharide export system protein LptC	188
2919289944	189	97.65	19	188	4	169	1.7e-59	194.5	COG1778	 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsC and related HAD superfamily phosphatases	170
2919289945	333	98.51	16	216	3	201	2.5e-79	259	COG0794	D-arabinose 5-phosphate isomerase GutQ	202
2919289946	661	76.68	402	581	21	191	8.8e-28	90.4	COG1226	Voltage-gated potassium channel Kch	212
2919289946	661	97.25	1	400	6	394	1.1e-93	308.1	COG0475	Kef-type K+ transport system, membrane component KefB	397
2919289947	1017	55.6	3	179	2	130	1.5e-09	30.9	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2919289947	1017	64.1	526	1016	216	640	3.2e-121	399.3	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2919289948	184	96.65	4	183	5	177	5.5e-61	199.2	COG0503	Adenine/guanine phosphoribosyltransferase or related PRPP-binding protein	179
2919289950	159	50.92	22	159	23	133	8.3e-21	68.7	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2919289951	473	99.56	3	473	3	454	0.0e+00	527.9	COG0486	tRNA U34 5-carboxymethylaminomethyl modifying GTPase MnmE/TrmE	454
2919289952	566	92.38	270	559	4	294	1.3e-95	314.3	COG0706	Membrane protein insertase Oxa1/YidC/SpoIIIJ, required for the localization of integral membrane proteins	314
2919289953	97	82.61	1	86	5	80	1.1e-32	105.8	COG0759	Membrane-anchored protein YidD, putatitve component of membrane protein insertase Oxa1/YidC/SpoIIIJ	92
2919289954	118	54.24	9	96	41	104	8.2e-10	32.8	COG0594	RNase P protein component	117
2919289955	44	100	1	44	1	44	3.3e-25	82.2	COG0230	Ribosomal protein L34	44
2919289956	474	99.77	22	470	1	432	0.0e+00	549.7	COG0593	Chromosomal replication initiation ATPase DnaA	408
2919289957	372	98.36	3	372	6	364	5.8e-104	342.3	COG0592	DNA polymerase III sliding clamp (beta) subunit, PCNA homolog	364
2919289958	872	99.69	33	872	3	641	0.0e+00	925.9	COG0187	DNA gyrase/topoisomerase IV, subunit B	635
2919289959	337	99.06	7	335	3	317	1.9e-86	284.4	COG4127	Predicted restriction endonuclease, Mrr-cat superfamily	318
2919289961	570	55.8	308	568	158	383	1.7e-36	39.3	COG0732	Restriction endonuclease S subunit	391
2919289961	570	56.54	18	267	154	382	1.7e-36	76.4	COG0732	Restriction endonuclease S subunit	391
2919289962	492	97.71	1	488	10	520	6.0e-97	319.6	COG0286	Type I restriction-modification system, DNA methylase subunit	489
2919289963	822	22.72	631	821	664	862	0.0e+00	78.7	COG4096	Type I site-specific restriction endonuclease, part of a restriction-modification system	875
2919289963	822	62.9	2	590	8	558	0.0e+00	656.8	COG4096	Type I site-specific restriction endonuclease, part of a restriction-modification system	875
2919289964	137	64.79	12	133	4	95	3.7e-15	50.5	COG0727	Fe-S-cluster containining protein	132
2919289965	546	97.54	13	546	4	557	0.0e+00	447.5	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2919289966	440	91.09	9	440	30	397	6.6e-51	167.8	COG1680	CubicO group peptidase, beta-lactamase class C family	390
2919289967	193	40	29	172	24	83	7.0e-10	32.9	COG0526	Thiol-disulfide isomerase or thioredoxin	127
2919289968	240	95.59	1	218	11	227	4.6e-40	131.7	COG0785	Cytochrome c biogenesis protein CcdA	220
2919289969	170	70.3	6	162	48	163	1.3e-10	35	COG4731	Uncharacterized conserved protein, DUF2147 family	162
2919289970	252	98.71	7	241	2	230	1.3e-78	257.7	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2919289971	439	84.77	65	439	56	389	2.0e-50	166.8	COG0642	Signal transduction histidine kinase	336
2919289972	270	93.98	17	270	2	251	2.0e-70	231.6	COG1801	Uncharacterized conserved protein YecE, DUF72 family	263
2919289973	100	88.17	6	98	4	85	3.8e-26	85.7	COG1254	Acylphosphatase	92
2919289974	81	62.1	1	81	37	113	7.0e-14	45.5	COG1145	Ferredoxin	99
2919289976	463	98.5	21	348	2	330	7.4e-103	338.5	COG0460	Homoserine dehydrogenase	333
2919289977	211	96.19	2	208	5	206	3.0e-69	226.8	COG2808	Predicted FMN-binding regulatory protein PaiB	209
2919289978	159	90.91	1	154	9	138	7.6e-24	78.7	COG1764	Organic hydroperoxide reductase OsmC/OhrA	143
2919289979	480	98.9	9	480	2	452	0.0e+00	435	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
2919289980	369	86.42	73	334	6	234	5.1e-61	200.2	COG2220	L-ascorbate metabolism protein UlaG, beta-lactamase superfamily	258
2919289981	245	89.95	1	210	11	198	6.4e-28	93	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2919289982	192	94.35	1	181	6	172	6.8e-59	192.4	COG0663	Carbonic anhydrase or acetyltransferase, isoleucine patch superfamily	176
2919289985	720	96.02	15	718	9	659	7.5e-127	418.3	COG1199	Rad3-related DNA helicase	654
2919289986	118	99.11	3	118	2	112	1.6e-42	138.4	COG2824	Uncharacterized Zn-ribbon-containing protein	112
2919289987	167	93.1	2	148	4	138	7.1e-32	104.4	COG3871	General stress protein 26 (function unknown)	145
2919289988	469	88.86	3	368	35	393	2.0e-50	166.7	COG1680	CubicO group peptidase, beta-lactamase class C family	390
2919289989	203	66.14	1	195	19	186	1.0e-38	128	COG0847	DNA polymerase III, epsilon subunit or related 3'-5' exonuclease	243
2919289990	198	98.63	6	198	1	216	3.1e-44	142.8	COG4094	Uncharacterized membrane protein	219
2919289992	165	94.87	13	157	5	152	2.4e-19	63.2	COG0328	Ribonuclease HI	154
2919289993	175	93.33	7	144	6	131	1.8e-26	86.8	COG3791	Uncharacterized conserved protein	133
2919289994	425	97.35	5	424	4	407	0.0e+00	537.7	COG4941	Predicted RNA polymerase sigma factor, contains C-terminal TPR domain	415
2919289995	135	96.99	1	133	1	129	7.9e-53	172.3	COG3607	Predicted lactoylglutathione lyase	133
2919289996	178	71.34	20	174	8	119	3.1e-09	31.1	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
2919289997	138	96.75	1	125	1	119	9.2e-37	120.1	COG3795	Uncharacterized conserved protein	123
2919289998	650	92.83	2	650	58	795	5.2e-52	171.7	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2919290000	637	43.06	18	170	12	104	2.0e-05	18.2	COG3726	Uncharacterized membrane protein affecting hemolysin expression	214
2919290000	637	63.65	160	635	219	640	7.4e-128	421.9	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2919290001	146	91.06	26	144	1	112	1.9e-29	96.4	COG3795	Uncharacterized conserved protein	123
2919290002	559	95.88	29	463	2	397	1.2e-119	394.1	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
2919290003	171	54.22	8	169	110	244	3.2e-40	133.2	COG0791	Cell wall-associated hydrolase, NlpC family	197
2919290004	366	99.15	15	364	3	350	0.0e+00	526.5	COG0722	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase	351
2919290005	163	85.11	15	155	16	135	6.5e-21	68.6	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
2919290006	152	81.06	1	129	1	107	3.8e-25	82.9	COG0789	DNA-binding transcriptional regulator, MerR family	124
2919290008	1630	30.55	4	202	46	213	6.7e-10	4.1	COG3604	Transcriptional regulator containing GAF, AAA-type ATPase, and DNA-binding Fis domains	550
2919290008	1630	31.27	415	626	32	203	6.7e-10	24.5	COG3604	Transcriptional regulator containing GAF, AAA-type ATPase, and DNA-binding Fis domains	550
2919290008	1630	65.61	1129	1628	206	640	5.9e-116	381.6	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2919290010	193	88.75	10	167	3	144	4.0e-06	21.5	COG3678	Periplasmic protein refolding chaperone Spy/CpxP family	160
2919290011	356	98.68	1	296	3	301	1.7e-85	281	COG2974	DNA recombination-dependent growth factor C	303
2919290012	251	94.74	62	251	3	182	1.4e-54	178.7	COG3703	Cation transport regulator ChaC	190
2919290013	257	32.5	1	90	1	91	8.6e-44	63.8	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
2919290013	257	57.86	102	256	86	247	8.6e-44	80.1	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
2919290015	277	97.36	19	274	6	263	1.3e-70	232	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2919290016	600	96.57	2	600	17	608	0.0e+00	543.3	COG1022	Long-chain acyl-CoA synthetase (AMP-forming)	613
2919290017	272	99.58	7	249	2	237	9.6e-91	297.3	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2919290018	393	87.16	14	371	7	325	1.8e-31	103.6	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2919290019	345	96.59	18	337	10	321	3.8e-76	250.6	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2919290020	296	98.67	6	295	3	299	2.6e-65	215.2	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2919290021	280	99.21	10	264	3	254	2.1e-98	322.9	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2919290022	293	95.22	60	261	8	206	2.5e-27	90.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2919290023	172	96.97	27	145	2	129	2.5e-32	106.1	COG0789	DNA-binding transcriptional regulator, MerR family	124
2919290024	68	94.52	3	68	2	70	1.5e-15	51.7	COG2608	Copper chaperone CopZ	71
2919290025	753	99.18	15	753	4	728	0.0e+00	840.2	COG2217	Cation transport ATPase	713
2919290026	555	91.76	53	519	36	425	2.6e-107	353.8	COG0840	Methyl-accepting chemotaxis protein	408
2919290027	195	77.25	2	178	11	156	4.5e-18	59.9	COG3945	Hemerythrin-like domain	189
2919290028	367	98.07	1	367	3	358	2.0e-113	373.7	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
2919290029	408	94.94	12	408	11	385	1.1e-14	47.9	COG2814	Predicted arabinose efflux permease, MFS family	394
2919290030	202	98.6	1	200	1	212	1.6e-42	140	COG0625	Glutathione S-transferase	211
2919290031	257	88.84	11	238	2	200	1.2e-48	159.8	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
2919290032	151	66.13	14	149	63	185	2.7e-36	119.7	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
2919290033	301	84.95	12	179	21	178	3.5e-34	111.7	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2919290035	87	46.48	1	69	12	77	1.4e-04	15.2	COG0727	Fe-S-cluster containining protein	132
2919290036	198	93.48	3	195	2	173	2.3e-40	132.5	COG0431	NAD(P)H-dependent FMN reductase	184
2919290037	661	99.2	3	644	2	620	0.0e+00	927.5	COG0445	tRNA U34 5-carboxymethylaminomethyl modifying enzyme MnmG/GidA	621
2919290038	228	97.21	12	227	2	210	1.7e-54	178.6	COG0357	16S rRNA G527 N7-methylase RsmG (former glucose-inhibited division protein B)	215
2919290039	204	97.6	2	204	4	206	3.6e-53	174.1	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
2919290040	270	98.48	1	256	1	260	6.0e-75	246.6	COG1192	Cellulose biosynthesis protein BcsQ	259
2919290041	180	96.13	2	180	3	176	2.6e-61	200.8	COG3545	Predicted esterase of the alpha/beta hydrolase fold	181
2919290042	68	15.03	4	40	99	121	1.7e-02	5.7	COG3088	Cytochrome c-type biogenesis protein CcmH/NrfF	153
2919290042	68	16.99	36	68	112	137	1.7e-02	5.8	COG3088	Cytochrome c-type biogenesis protein CcmH/NrfF	153
2919290043	98	41.98	7	97	57	111	2.5e-13	44.3	COG1917	Cupin domain protein related to quercetin dioxygenase	131
2919290044	305	91.29	36	287	7	247	5.7e-66	217.2	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
2919290047	512	86.19	11	431	13	399	6.6e-44	144.1	COG3014	Uncharacterized protein	449
2919290048	135	65.85	9	132	41	121	8.9e-07	23.2	COG5633	Uncharacterized conserved protein YcfL	123
2919290049	205	97	4	202	7	200	4.5e-25	82.7	COG3417	Outer membrane lipoprotein LpoB, binds and activates PBP1b	200
2919290052	211	94.05	7	206	8	181	2.7e-45	148.4	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
2919290053	515	21.63	323	398	109	153	3.7e-03	6.7	COG3166	Tfp pilus assembly protein PilN	206
2919290053	515	25	417	489	107	158	3.7e-03	3.8	COG3166	Tfp pilus assembly protein PilN	206
2919290054	313	78.79	177	311	20	123	7.0e-20	65.1	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2919290055	425	46.48	18	232	17	194	6.8e-24	57.6	COG0477	MFS family permease	338
2919290055	425	50.91	225	425	8	202	6.8e-24	27.7	COG0477	MFS family permease	338
2919290056	170	86.53	1	170	26	192	1.0e-63	208.9	COG3812	Uncharacterized protein	193
2919290057	313	98.01	1	309	1	295	2.3e-60	199.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919290059	744	99.73	1	744	1	742	0.0e+00	1354.8	COG2838	Monomeric isocitrate dehydrogenase	744
2919290060	245	76.15	31	229	13	194	1.1e-27	90.8	COG1407	Metallophosphoesterase superfamily enzyme	235
2919290061	907	96.07	13	866	13	843	0.0e+00	525.9	COG1201	Lhr-like helicase	814
2919290062	565	97.15	58	558	12	489	3.9e-80	264	COG1793	ATP-dependent DNA ligase	444
2919290063	353	94.28	2	335	18	429	4.7e-35	113	COG1236	RNA processing exonuclease, beta-lactamase fold, Cft2 family	427
2919290067	534	94.64	2	533	17	563	5.1e-89	293.8	COG0747	ABC-type transport system, periplasmic component	556
2919290068	108	97.25	1	108	1	106	1.1e-43	142.2	COG1742	Uncharacterized inner membrane protein YnfA, drug/metabolite transporter superfamily	109
2919290069	242	80.51	1	101	15	109	3.2e-15	50.3	COG0640	DNA-binding transcriptional regulator, ArsR family	110
2919290071	118	97.17	1	102	1	103	3.4e-24	79.1	COG2329	Heme-degrading monooxygenase HmoA and related ABM domain proteins	105
2919290074	474	97.23	21	473	11	466	2.5e-124	409.7	COG0277	FAD/FMN-containing dehydrogenase	459
2919290075	224	90.43	5	213	8	196	7.7e-16	53.5	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2919290076	332	97.18	6	331	8	317	8.1e-66	216.5	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2919290077	502	92.71	6	495	7	464	6.0e-103	339.6	COG2272	Carboxylesterase type B	491
2919290078	190	12.8	1	70	71	107	8.6e-07	1.4	COG5473	Uncharacterized membrane protein	290
2919290078	190	35.99	50	189	179	282	8.6e-07	23	COG5473	Uncharacterized membrane protein	290
2919290080	264	91.81	1	213	16	228	8.5e-53	173.3	COG1802	DNA-binding transcriptional regulator, GntR family	230
2919290081	276	94.7	12	275	7	274	4.1e-52	171.3	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2919290082	224	93.86	1	224	12	225	4.7e-62	203.9	COG0765	ABC-type amino acid transport system, permease component	222
2919290083	217	92.54	1	216	15	225	1.3e-71	235.2	COG0765	ABC-type amino acid transport system, permease component	222
2919290084	264	99.17	22	263	2	241	1.1e-108	356.2	COG1126	ABC-type polar amino acid transport system, ATPase component	240
2919290087	189	97.84	2	182	2	182	3.5e-62	203.4	COG2096	Cob(I)alamin adenosyltransferase	184
2919290089	142	95.04	2	141	6	139	4.8e-37	121.2	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
2919290090	383	89.62	9	370	8	335	4.5e-41	135.2	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2919290091	513	99.22	2	505	4	510	0.0e+00	640.1	COG0427	Acyl-CoA hydrolase	501
2919290092	429	94.74	10	429	9	440	1.2e-118	390.6	COG2233	Xanthine/uracil permease	451
2919290093	248	46.15	133	184	8	37	5.6e-03	8.6	COG3024	Endogenous inhibitor of DNA gyrase, YacG/DUF329 family	65
2919290093	248	46.59	5	75	4	44	3.1e-06	21.5	COG3809	Predicted nucleic acid-binding protein, contains Zn-finger domain	88
2919290094	303	84.67	33	281	13	266	3.4e-32	105.7	COG3315	O-Methyltransferase involved in polyketide biosynthesis	297
2919290095	423	98.73	4	411	1	388	6.1e-81	267	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2919290096	143	9.89	1	107	119	173	4.4e-03	10.1	COG2194	Phosphoethanolamine transferase for periplasmic glucans (OPG), alkaline phosphatase superfamily	555
2919290097	298	92.2	32	298	21	292	7.6e-20	59.5	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2919290099	203	81.82	1	200	8	178	5.3e-16	54.3	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2919290100	690	99.09	75	664	1	547	2.6e-123	406.3	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
2919290101	333	97.18	7	331	7	316	5.6e-82	269.4	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2919290102	649	96.48	34	583	11	558	6.4e-90	296.1	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2919290103	208	75.11	8	208	3	180	2.5e-48	159.1	COG1183	Phosphatidylserine synthase	234
2919290104	280	96.92	1	280	6	288	2.0e-61	202.4	COG0384	Predicted epimerase YddE/YHI9, PhzF superfamily	291
2919290105	293	98.01	6	293	2	296	7.9e-63	207.3	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919290106	387	95.63	205	387	8	182	9.0e-57	185.9	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2919290107	306	96.35	6	305	7	296	2.4e-46	152.6	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2919290108	252	98.25	12	252	3	227	7.9e-58	190.4	COG0850	Septum formation inhibitor MinC	219
2919290109	271	98.53	1	271	1	268	2.1e-128	421.5	COG2894	Septum formation inhibitor-activating ATPase MinD	272
2919290110	88	93.18	2	88	2	83	1.3e-31	102.6	COG0851	Septum formation topological specificity factor MinE	88
2919290111	732	98.1	8	731	2	674	2.8e-113	373.7	COG1289	Uncharacterized membrane protein YccC	674
2919290112	196	84.58	6	196	3	183	1.8e-42	139.7	COG2258	Uncharacterized conserved protein YiiM, contains MOSC domain	210
2919290113	173	84.32	9	172	10	165	5.3e-43	141	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
2919290114	263	93.22	3	259	20	294	1.2e-41	137.4	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2919290115	252	93.94	14	247	7	223	9.4e-32	104.6	COG1434	Uncharacterized SAM-binding protein YcdF, DUF218 family	223
2919290116	188	60.09	6	182	13	140	4.6e-12	40.3	COG0655	Multimeric flavodoxin WrbA	207
2919290117	445	94.59	1	440	5	371	2.3e-65	215.4	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2919290118	303	97.34	4	302	4	296	2.5e-41	136.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919290119	204	82.3	3	204	11	182	1.4e-23	79.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2919290120	312	67.32	173	312	63	200	2.3e-64	109	COG2335	Uncaracterized surface protein containing fasciclin (FAS1) repeats	187
2919290120	312	71.71	2	176	55	201	2.3e-64	104.7	COG2335	Uncaracterized surface protein containing fasciclin (FAS1) repeats	187
2919290121	151	71.22	4	151	55	200	1.9e-52	172.5	COG2335	Uncaracterized surface protein containing fasciclin (FAS1) repeats	187
2919290122	140	94.34	1	140	7	156	3.3e-22	74.1	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2919290123	276	36.1	1	180	4	90	1.5e-03	11.6	COG2908	UDP-2,3-diacylglucosamine pyrophosphatase LpxH	237
2919290124	325	99.34	9	318	1	299	2.0e-46	153.4	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919290125	146	44.85	9	105	43	103	3.1e-03	11.5	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
2919290126	623	98.68	4	623	8	607	0.0e+00	926.5	COG1274	Phosphoenolpyruvate carboxykinase, GTP-dependent	608
2919290127	236	94.14	2	235	4	212	1.8e-69	227.7	COG0603	7-cyano-7-deazaguanine synthase (queuosine biosynthesis)	222
2919290129	399	96.82	1	334	7	341	6.1e-117	384.8	COG1171	Threonine dehydratase	347
2919290130	525	93.09	1	525	35	546	0.0e+00	581.5	COG3604	Transcriptional regulator containing GAF, AAA-type ATPase, and DNA-binding Fis domains	550
2919290131	760	99.16	3	748	2	712	0.0e+00	896.2	COG3256	Nitric oxide reductase large subunit	717
2919290132	142	25.79	3	137	104	160	5.4e-05	16.9	COG2846	Iron-sulfur cluster repair protein YtfE, RIC family, contains ScdAN and hemerythrin domains	221
2919290134	627	98.67	8	627	4	597	0.0e+00	715.2	COG0514	Superfamily II DNA helicase RecQ	590
2919290135	354	98.72	5	342	4	311	1.6e-120	396.4	COG0646	Methionine synthase I (cobalamin-dependent), methyltransferase domain	311
2919290136	315	80.19	32	289	2	248	8.1e-68	222.9	COG0037	tRNA(Ile)-lysidine synthase TilS/MesJ	298
2919290137	479	99.14	2	413	2	348	0.0e+00	466.7	COG0826	Collagenase-like protease, PrtC family	347
2919290142	505	97.42	5	473	4	456	2.6e-110	363.3	COG2211	Na+/melibiose symporter or related transporter	467
2919290143	559	92.75	17	536	31	542	9.9e-63	205.9	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
2919290144	435	98.79	25	434	6	412	0.0e+00	543.2	COG0334	Glutamate dehydrogenase/leucine dehydrogenase	411
2919290146	303	86.67	22	288	30	263	6.2e-81	265.9	COG2326	Polyphosphate kinase 2, PPK2 family	270
2919290147	329	96.62	4	329	4	317	2.0e-48	159.3	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
2919290148	278	94.34	1	267	8	257	2.5e-18	60.4	COG2220	L-ascorbate metabolism protein UlaG, beta-lactamase superfamily	258
2919290149	313	97.67	3	311	3	296	9.8e-46	151.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919290150	151	92.62	8	151	7	144	4.2e-49	160.5	COG4125	Uncharacterized membrane protein	149
2919290153	913	98.95	2	883	10	857	0.0e+00	1267.5	COG1410	Methionine synthase I, cobalamin-binding domain	842
2919290154	133	91.91	3	130	11	135	2.7e-26	86.4	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
2919290155	309	98.01	2	301	2	296	2.0e-70	232.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919290157	180	95.35	1	174	5	168	1.2e-54	179.2	COG0703	Shikimate kinase	172
2919290158	389	82.43	1	389	46	378	4.2e-62	205	COG1680	CubicO group peptidase, beta-lactamase class C family	390
2919290159	563	96.13	18	562	15	560	0.0e+00	434.3	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2919290160	257	98.88	7	255	2	266	1.2e-67	222.5	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2919290161	334	90.76	17	328	15	289	1.2e-45	150.1	COG1295	Uncharacterized membrane protein, BrkB/YihY/UPF0761 family (not an RNase)	303
2919290162	266	67.53	120	239	42	145	1.7e-17	58.2	COG3133	Outer membrane lipoprotein SlyB	154
2919290163	395	12.53	10	106	28	78	4.3e-17	37	COG1228	Imidazolonepropionase or related amidohydrolase	406
2919290163	395	13.27	143	233	265	318	4.3e-17	3	COG1228	Imidazolonepropionase or related amidohydrolase	406
2919290163	395	17.2	257	365	309	378	4.3e-17	17.5	COG1228	Imidazolonepropionase or related amidohydrolase	406
2919290164	240	81.34	8	228	11	180	4.8e-21	70.5	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2919290165	258	98.88	1	255	4	268	1.6e-62	205.6	COG1018	Ferredoxin-NADP reductase	266
2919290166	109	90.41	1	65	5	70	3.2e-18	59.8	COG1146	NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit	68
2919290168	287	84.77	1	248	24	240	4.0e-40	131.7	COG2122	Uncharacterized protein, UPF0280 family, ApbE superfamily	256
2919290171	403	89.62	9	384	28	355	3.3e-55	181.8	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2919290172	635	88.85	3	307	33	319	1.1e-100	102.6	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2919290172	635	96.59	318	623	8	319	1.1e-100	235.1	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2919290173	260	98.82	1	245	4	254	7.5e-81	265.4	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2919290174	249	98.73	10	249	3	236	1.2e-86	283.9	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2919290175	241	92.72	34	240	5	195	5.7e-53	173.8	COG1335	Nicotinamidase-related amidase	205
2919290176	390	92.35	18	386	9	346	6.8e-47	154.4	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2919290177	168	94.23	7	165	7	153	3.8e-55	179.9	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
2919290178	1247	18.12	43	199	457	591	3.0e-93	54.8	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
2919290178	1247	41.46	778	892	26	93	5.3e-32	11.1	COG2010	Cytochrome c, mono- and diheme variants	150
2919290178	1247	62.2	1104	1246	50	151	5.3e-32	37.6	COG2010	Cytochrome c, mono- and diheme variants	150
2919290178	1247	85.77	116	765	105	743	3.0e-93	268.7	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
2919290178	1247	99.39	929	1101	1	163	5.3e-32	72.6	COG2010	Cytochrome c, mono- and diheme variants	150
2919290182	206	96.15	4	204	3	202	1.3e-22	74.1	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
2919290183	149	80.38	1	141	4	130	1.2e-31	104.1	COG1522	DNA-binding transcriptional regulator, Lrp family	154
2919290184	142	97.26	10	126	3	144	2.0e-12	39.8	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2919290185	125	94.49	1	125	6	125	4.0e-27	89.4	COG3324	Predicted enzyme related to lactoylglutathione lyase	127
2919290186	293	78.79	164	289	22	125	7.9e-27	87.3	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2919290187	390	99.75	1	387	1	392	8.0e-71	233.8	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2919290188	53	9.09	1	49	310	349	5.7e-04	10.5	COG0201	Preprotein translocase subunit SecY	436
2919290190	149	66.13	8	147	63	185	2.8e-29	96.8	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
2919290191	570	19.81	144	265	120	181	8.3e-07	14.5	COG3509	Poly(3-hydroxybutyrate) depolymerase	312
2919290191	570	28.12	398	530	160	247	8.3e-07	8.3	COG3509	Poly(3-hydroxybutyrate) depolymerase	312
2919290192	575	96.74	18	450	8	393	3.0e-93	306.8	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2919290193	329	96.87	5	327	9	317	2.3e-65	215	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2919290194	254	98.88	1	250	1	265	2.6e-53	175.5	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2919290195	625	37.52	338	616	375	604	2.6e-54	107.7	COG1022	Long-chain acyl-CoA synthetase (AMP-forming)	613
2919290195	625	42.74	66	353	40	301	2.6e-54	69.3	COG1022	Long-chain acyl-CoA synthetase (AMP-forming)	613
2919290196	260	98.49	1	257	3	263	1.6e-59	195.7	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2919290197	294	93.42	1	289	19	302	2.2e-69	228.5	COG2159	Predicted metal-dependent hydrolase, TIM-barrel fold	293
2919290199	166	87.97	38	165	15	131	6.9e-23	75.3	COG1846	DNA-binding transcriptional regulator, MarR family	126
2919290200	514	98.98	15	512	1	487	0.0e+00	598.2	COG0606	Predicted ATPase with chaperone activity	490
2919290202	112	100	1	112	1	112	1.8e-49	161.2	COG0347	Nitrogen regulatory protein PII	112
2919290203	514	98.3	72	514	2	406	0.0e+00	505.6	COG0004	Ammonia channel protein AmtB	409
2919290204	379	89.55	5	378	48	467	4.6e-47	147.6	COG0277	FAD/FMN-containing dehydrogenase	459
2919290205	269	91.59	10	236	4	210	4.9e-24	78.5	COG3619	Uncharacterized membrane protein YoaK, UPF0700 family	226
2919290206	418	98.75	15	417	4	399	3.2e-76	251	COG0247	Fe-S oxidoreductase	388
2919290208	163	89.17	3	157	7	146	1.0e-18	62.3	COG3708	Predicted transcriptional regulator YdeE, contains AraC-type DNA-binding domain	157
2919290209	214	96.28	8	206	4	210	7.4e-45	147.4	COG0625	Glutathione S-transferase	211
2919290210	245	74.12	1	238	4	235	3.6e-71	234.4	COG2378	Predicted DNA-binding transcriptional regulator YafY, contains an HTH and WYL domains	311
2919290211	849	16.19	764	822	140	184	4.2e-16	19.1	COG4253	Uncharacterized conserved protein, DUF2345 family	278
2919290211	849	60.43	606	777	2	169	4.2e-16	42.4	COG4253	Uncharacterized conserved protein, DUF2345 family	278
2919290211	849	92.21	2	594	14	546	0.0e+00	568.9	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
2919290212	143	95.92	1	143	2	142	4.6e-29	95.6	COG5435	Uncharacterized protein	147
2919290213	1575	8.64	543	635	48	121	6.5e-74	20.3	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
2919290213	1575	9.81	871	977	518	601	6.5e-74	7.3	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
2919290213	1575	12.73	734	853	42	150	6.5e-74	50.6	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
2919290213	1575	14.84	625	759	24	150	6.5e-74	78	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
2919290213	1575	27.57	320	567	175	410	6.5e-74	13.5	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
2919290213	1575	55.61	955	1541	231	706	6.5e-74	111.2	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
2919290213	1575	63	42	131	17	79	8.1e-09	12.3	COG4104	Zn-binding Pro-Ala-Ala-Arg (PAAR) domain, incolved in TypeVI secretion	98
2919290213	1575	76	100	191	24	99	8.1e-09	30.1	COG4104	Zn-binding Pro-Ala-Ala-Arg (PAAR) domain, incolved in TypeVI secretion	98
2919290215	310	31.43	2	310	424	692	5.5e-25	77	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
2919290219	163	97.53	1	162	3	160	5.1e-73	238	COG0386	Glutathione peroxidase, house-cleaning role in reducing lipid peroxides	162
2919290220	299	95.68	1	293	8	295	3.5e-26	86.4	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2919290221	434	96.08	2	412	3	370	4.1e-13	43.7	COG0477	MFS family permease	338
2919290222	371	98.63	1	368	2	360	4.5e-107	352.3	COG0787	Alanine racemase	360
2919290224	163	97.74	8	144	3	132	8.1e-24	78.5	COG1846	DNA-binding transcriptional regulator, MarR family	126
2919290225	270	96.24	11	262	9	264	1.1e-70	232.2	COG2375	NADPH-dependent ferric siderophore reductase, contains FAD-binding and SIP domains	265
2919290226	295	98.01	3	294	2	296	1.5e-43	143.9	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919290227	202	97.52	2	202	3	199	1.7e-61	201.6	COG1279	Arginine exporter protein ArgO	202
2919290228	526	93.25	1	521	20	558	1.7e-100	331.8	COG0747	ABC-type transport system, periplasmic component	556
2919290229	207	97.21	4	207	1	209	5.9e-43	141.5	COG0625	Glutathione S-transferase	211
2919290230	325	99.35	1	325	1	307	1.0e-75	247.5	COG1893	Ketopantoate reductase	307
2919290231	276	98.82	1	264	3	254	7.5e-107	350.5	COG3836	2-keto-3-deoxy-L-rhamnonate aldolase RhmA	255
2919290232	459	99.56	1	459	1	454	0.0e+00	640.1	COG1066	Predicted ATP-dependent serine protease	456
2919290234	316	99.3	12	306	2	284	6.3e-95	312.5	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
2919290235	68	59.68	5	60	25	61	9.6e-17	54.8	COG4391	Uncharacterized conserved protein, contains Zn-finger domain	62
2919290236	271	31.75	10	266	3	116	2.6e-22	74.7	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
2919290237	428	73.43	57	416	97	411	1.0e-23	78.4	COG3307	O-antigen ligase	424
2919290238	324	20.29	1	161	1	83	1.0e-15	8	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2919290238	324	54.52	106	304	185	407	1.0e-15	44.2	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2919290239	373	97.68	1	367	3	339	5.8e-80	263.3	COG2070	NAD(P)H-dependent flavin oxidoreductase YrpB, nitropropane dioxygenase family	336
2919290240	295	97.67	2	292	1	294	8.3e-62	203.8	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919290242	418	82.99	28	418	64	390	3.1e-61	202.4	COG0642	Signal transduction histidine kinase	336
2919290243	240	99.14	3	239	2	231	2.4e-83	273.2	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2919290244	464	48.83	270	462	10	196	8.4e-08	13.6	COG0477	MFS family permease	338
2919290244	464	70.23	30	304	8	276	8.4e-08	15.4	COG0477	MFS family permease	338
2919290245	283	65.38	11	273	103	306	6.0e-34	111.9	COG0501	Zn-dependent protease with chaperone function	302
2919290246	366	95.63	175	354	8	182	2.5e-58	191	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2919290247	212	90.77	1	210	13	248	9.1e-51	167.1	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2919290248	204	83.17	1	198	6	173	6.8e-25	82.1	COG1776	Chemotaxis protein CheY-P-specific phosphatase CheC	203
2919290249	120	88.72	1	120	6	123	1.6e-22	74.1	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2919290250	551	94.54	364	544	8	180	4.9e-55	180.7	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2919290251	182	84.52	12	182	24	154	1.1e-37	123.7	COG3915	Uncharacterized protein	155
2919290252	635	97.44	100	635	12	506	0.0e+00	498.7	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
2919290253	267	99.61	2	265	1	258	9.8e-79	258.6	COG0708	Exonuclease III	261
2919290254	232	99.51	13	227	2	203	9.2e-62	202.6	COG0461	Orotate phosphoribosyltransferase	201
2919290256	482	98.55	5	482	6	481	0.0e+00	658.5	COG0064	Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit	483
2919290257	497	99.38	3	495	3	480	0.0e+00	571.3	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
2919290258	99	98.96	1	99	1	95	1.3e-23	77.5	COG0721	Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit	96
2919290259	347	98.24	5	347	2	336	0.0e+00	500	COG1077	Actin-like ATPase involved in cell morphogenesis	342
2919290260	307	97.55	12	297	3	281	5.0e-61	200.5	COG1792	Cell shape-determining protein MreC	284
2919290261	172	93.41	8	164	4	159	1.6e-28	93.9	COG2891	Cell shape-determining protein MreD	167
2919290262	646	98.42	2	619	5	626	0.0e+00	519	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
2919290263	295	97.01	1	291	4	295	4.8e-37	122.1	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2919290264	251	98.76	10	250	3	241	1.5e-110	362.3	COG1126	ABC-type polar amino acid transport system, ATPase component	240
2919290265	260	91.67	30	257	18	226	7.5e-75	245.9	COG0765	ABC-type amino acid transport system, permease component	222
2919290266	254	93.29	1	251	11	274	2.9e-55	181.8	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2919290267	252	96.91	1	251	5	255	1.5e-45	149.7	COG0730	Uncharacterized membrane protein YfcA	258
2919290268	450	97.57	48	449	2	403	0.0e+00	492.7	COG0004	Ammonia channel protein AmtB	409
2919290270	122	83.02	14	104	16	103	3.0e-06	21.3	COG2329	Heme-degrading monooxygenase HmoA and related ABM domain proteins	105
2919290271	563	97.54	1	563	5	558	0.0e+00	438.4	COG2303	Choline dehydrogenase or related flavoprotein	542
2919290272	374	96.63	105	374	8	265	2.1e-80	263.9	COG0767	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, permease component MlaE	267
2919290273	291	94.68	14	276	7	255	6.5e-91	298.3	COG1127	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, ATPase component MlaF	263
2919290274	322	75.41	1	292	1	279	5.6e-27	84.4	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2919290275	229	92.68	8	229	15	204	1.7e-14	47.5	COG3218	ABC-type uncharacterized transport system, auxiliary component	205
2919290276	458	98.05	8	436	3	404	0.0e+00	432.7	COG1252	NADH dehydrogenase, FAD-containing subunit	405
2919290277	484	94.98	4	472	8	404	1.1e-68	226.2	COG4102	Uncharacterized conserved protein, DUF1501 family	418
2919290278	627	64.11	77	529	138	455	2.0e-65	214.9	COG5267	Uncharacterized conserved protein, DUF1800 family	496
2919290279	72	92.54	1	65	5	66	4.5e-21	69.1	COG3237	Uncharacterized conserved protein YjbJ, UPF0337 family	67
2919290280	193	24.44	1	188	369	511	4.9e-03	10.4	COG2812	DNA polymerase III, gamma/tau subunits	515
2919290281	178	88.19	2	133	2	128	1.2e-20	68.1	COG2703	Hemerythrin	144
2919290282	348	95.63	147	348	8	182	7.2e-49	160.1	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2919290284	478	97.52	1	464	2	433	1.9e-118	390	COG4452	Inner membrane protein involved in colicin E2 resistance	443
2919290286	488	83.25	96	488	57	384	1.1e-52	174.3	COG0642	Signal transduction histidine kinase	336
2919290287	236	98.28	3	236	2	229	1.6e-74	244.4	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2919290288	211	95.12	2	208	10	204	3.9e-57	187.1	COG2095	Small neutral amino acid transporter SnatA, MarC family	203
2919290289	248	98.13	1	248	5	267	7.2e-63	207	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2919290290	229	99.58	1	229	1	236	5.6e-59	193.7	COG0412	Dienelactone hydrolase	236
2919290292	424	23.17	12	176	58	133	3.8e-38	11.1	COG0598	Mg2+ and Co2+ transporter CorA	322
2919290292	424	58.84	211	420	136	328	3.8e-38	112.4	COG0598	Mg2+ and Co2+ transporter CorA	322
2919290293	335	98.18	6	335	5	328	0.0e+00	487.3	COG0113	Delta-aminolevulinic acid dehydratase, porphobilinogen synthase	330
2919290294	142	95.3	1	142	8	149	5.9e-51	167	COG1981	Uncharacterized membrane protein	149
2919290295	367	56	7	136	49	132	2.6e-11	36.8	COG5652	VanZ like family protein (function unknown)	148
2919290296	119	85.94	58	116	2	56	8.2e-24	77.5	COG3411	(2Fe-2S) ferredoxin	64
2919290297	216	96.19	2	215	3	204	1.2e-56	185.5	COG2945	Alpha/beta superfamily hydrolase	210
2919290298	389	97.2	1	389	8	389	2.8e-120	396.4	COG1686	D-alanyl-D-alanine carboxypeptidase	389
2919290299	125	95.35	1	123	7	129	8.8e-63	203.9	COG0048	Ribosomal protein S12	129
2919290300	157	99.32	2	150	2	148	1.3e-59	194.4	COG0049	Ribosomal protein S7	148
2919290301	700	99.31	1	700	1	724	0.0e+00	983	COG0480	Translation elongation factor EF-G, a GTPase	697
2919290302	396	99.75	1	396	1	393	0.0e+00	754.3	COG0050	Translation elongation factor EF-Tu, a GTPase	394
2919290303	103	99.04	1	103	1	103	5.4e-45	146.1	COG0051	Ribosomal protein S10	104
2919290304	224	98.24	6	223	2	224	1.0e-72	238.9	COG0087	Ribosomal protein L3	218
2919290305	206	97.7	1	206	2	213	4.9e-68	223	COG0088	Ribosomal protein L4	214
2919290306	104	96.81	11	103	2	92	3.2e-31	102.1	COG0089	Ribosomal protein L23	94
2919290307	269	98.18	1	269	6	275	1.5e-118	389.5	COG0090	Ribosomal protein L2	275
2919290308	91	97.85	1	91	1	91	1.2e-43	141.2	COG0185	Ribosomal protein S19	93
2919290309	110	89.93	1	110	11	144	3.5e-41	134.9	COG0091	Ribosomal protein L22	120
2919290310	293	91.85	12	239	2	215	2.7e-95	312.2	COG0092	Ribosomal protein S3	233
2919290311	138	93.29	1	137	2	140	1.0e-56	185	COG0197	Ribosomal protein L16/L10AE	146
2919290312	65	91.18	1	65	4	65	9.6e-22	71.2	COG0255	Ribosomal protein L29	69
2919290313	89	93.1	2	88	5	85	9.6e-34	109.6	COG0186	Ribosomal protein S17	87
2919290314	169	98.8	1	166	2	165	5.8e-62	202.3	COG0678	Peroxiredoxin	165
2919290315	167	64.02	18	166	56	176	4.4e-16	53.7	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
2919290316	225	94.79	2	192	4	185	1.6e-43	142.2	COG3658	Cytochrome b	192
2919290317	151	95.92	2	151	6	146	9.2e-34	111	COG3909	Cytochrome c556	147
2919290318	167	91.72	25	166	9	152	3.7e-16	53.2	COG1225	Peroxiredoxin	157
2919290320	426	93.92	15	417	10	380	1.5e-17	57.2	COG2814	Predicted arabinose efflux permease, MFS family	394
2919290321	150	94.41	3	143	3	137	1.5e-27	90.3	COG2893	Phosphotransferase system, mannose/fructose-specific component IIA	143
2919290322	89	98.88	1	88	1	88	4.6e-28	91.5	COG1925	Phosphotransferase system, HPr and related phosphotransfer proteins	88
2919290323	589	96.52	3	586	3	556	0.0e+00	625.7	COG1080	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria)	574
2919290324	277	95.68	1	277	5	292	2.5e-31	103.4	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2919290325	237	70.45	120	234	21	113	4.6e-16	52.5	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2919290326	326	97.06	20	326	6	302	0.0e+00	463.7	COG0320	Lipoate synthase	306
2919290327	231	89.33	1	231	11	211	4.8e-71	232.8	COG0321	Lipoate-protein ligase B	221
2919290328	105	94.44	15	105	6	90	3.9e-30	98.4	COG2921	Putative lipoic acid-binding regulatory protein	90
2919290329	157	82.03	35	154	18	122	9.8e-11	36	COG3312	FoF1-type ATP synthase assembly protein I	128
2919290330	292	99.6	2	292	2	252	8.2e-75	245.7	COG0356	FoF1-type ATP synthase, membrane subunit a	246
2919290331	89	91.25	1	78	8	80	2.2e-23	76.5	COG0636	FoF1-type ATP synthase, membrane subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K	79
2919290332	156	96.27	1	156	4	158	1.8e-45	148.7	COG0711	FoF1-type ATP synthase, membrane subunit b or b'	161
2919290333	180	99.44	1	179	1	177	6.5e-47	153.9	COG0712	FoF1-type ATP synthase, delta subunit	178
2919290334	517	99.21	1	517	1	500	0.0e+00	782.5	COG0056	FoF1-type ATP synthase, alpha subunit	504
2919290335	288	99.65	5	288	1	287	2.4e-109	359.8	COG0224	FoF1-type ATP synthase, gamma subunit	287
2919290336	468	99.15	3	468	2	465	0.0e+00	778.6	COG0055	FoF1-type ATP synthase, beta subunit	468
2919290337	138	97.04	1	133	1	131	4.1e-44	143.8	COG0355	FoF1-type ATP synthase, epsilon subunit	135
2919290340	180	66.67	12	180	70	211	1.2e-31	104.5	COG3762	Uncharacterized membrane protein	213
2919290341	267	86.69	1	267	38	278	3.6e-61	200.3	COG1512	Uncharacterized membrane protein YgcG, contains a TPM-fold domain	271
2919290342	204	97.3	2	195	3	182	9.4e-67	218.2	COG1704	Uncharacterized conserved protein	185
2919290344	150	87.59	13	139	15	134	1.4e-13	45.3	COG4319	Ketosteroid isomerase homolog	137
2919290345	337	86.49	1	326	23	323	7.8e-89	292.1	COG0429	Predicted hydrolase of the alpha/beta-hydrolase fold	345
2919290347	283	92.06	33	156	9	124	3.7e-53	81.5	COG3245	Cytochrome c5	126
2919290347	283	92.06	158	283	10	125	3.7e-53	98.1	COG3245	Cytochrome c5	126
2919290348	477	98.7	17	477	1	454	4.4e-124	408.9	COG1538	Outer membrane protein TolC	457
2919290349	1051	99.8	1	1027	2	1013	0.0e+00	1195.7	COG0841	Multidrug efflux pump subunit AcrB	1009
2919290350	431	98.72	13	399	3	387	5.4e-78	256.9	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2919290351	218	86.12	1	211	6	185	2.3e-23	78.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2919290356	396	99.75	1	396	1	393	0.0e+00	754.3	COG0050	Translation elongation factor EF-Tu, a GTPase	394
2919290358	128	90.41	48	119	5	70	4.8e-21	68.5	COG0690	Preprotein translocase subunit SecE	73
2919290359	198	97.27	23	198	4	181	3.6e-64	209.9	COG0250	Transcription antitermination factor NusG	178
2919290360	143	99.29	2	143	1	140	2.1e-63	206.7	COG0080	Ribosomal protein L11	141
2919290361	231	99.57	1	227	1	229	6.1e-94	308	COG0081	Ribosomal protein L1	228
2919290362	174	93.18	1	170	3	166	1.3e-45	149.3	COG0244	Ribosomal protein L10	175
2919290363	125	100	1	125	1	125	3.7e-48	157.3	COG0222	Ribosomal protein L7/L12	124
2919290364	1370	99.45	1	1370	3	1082	0.0e+00	1455.2	COG0085	DNA-directed RNA polymerase, beta subunit/140 kD subunit	1060
2919290365	1411	41.06	895	1395	421	753	0.0e+00	30.3	COG0086	DNA-directed RNA polymerase, beta' subunit/160 kD subunit	808
2919290365	1411	99.63	12	852	3	810	0.0e+00	952.6	COG0086	DNA-directed RNA polymerase, beta' subunit/160 kD subunit	808
2919290367	442	99.16	87	441	3	357	2.4e-89	294.3	COG0144	16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family	355
2919290369	764	97.61	19	762	13	707	0.0e+00	580.9	COG5000	Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation	712
2919290370	227	11.13	152	226	410	461	4.8e-51	35.3	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2919290370	227	27.62	1	158	4	132	4.8e-51	131.2	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2919290372	417	70.3	4	416	7	432	4.8e-55	179.5	COG0443	Molecular chaperone DnaK (HSP70)	579
2919290373	309	98.9	21	302	3	271	4.0e-88	289	COG0313	16S rRNA C1402 (ribose-2'-O) methylase RsmI	275
2919290374	136	98.25	22	135	2	113	2.4e-31	102.1	COG0792	Predicted endonuclease distantly related to archaeal Holliday junction resolvase	114
2919290375	199	98.87	2	180	2	176	9.2e-54	175.9	COG0279	Phosphoheptose isomerase	176
2919290376	221	94.92	6	198	10	196	7.5e-40	131.2	COG2823	Osmotically-inducible protein OsmY, contains BON domain	196
2919290377	304	99.3	15	304	2	285	3.1e-104	342.3	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
2919290378	378	98.67	4	378	4	373	0.0e+00	620.4	COG5008	Tfp pilus assembly protein, ATPase PilU	375
2919290379	202	48.62	44	201	34	139	4.7e-17	56.4	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2919290380	347	96.88	1	346	4	345	0.0e+00	532.1	COG2805	Tfp pilus assembly protein PilT, pilus retraction ATPase	353
2919290381	228	94.32	1	225	13	228	5.3e-72	236.3	COG0325	Uncharacterized pyridoxal phosphate-containing protein, affects Ilv metabolism, UPF0001 family	228
2919290382	356	99.13	1	354	1	340	1.1e-100	331	COG2008	Threonine aldolase	342
2919290383	415	95.36	16	396	4	352	2.8e-43	142.2	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2919290384	216	66.99	8	214	8	147	3.3e-21	68.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2919290385	536	95.95	3	535	12	556	6.2e-121	398.4	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2919290386	1095	7.59	655	732	117	165	0.0e+00	4	COG4770	Acetyl/propionyl-CoA carboxylase, alpha subunit	645
2919290386	1095	11.92	471	562	568	644	0.0e+00	50.8	COG4770	Acetyl/propionyl-CoA carboxylase, alpha subunit	645
2919290386	1095	70.74	6	491	2	458	0.0e+00	503.9	COG4770	Acetyl/propionyl-CoA carboxylase, alpha subunit	645
2919290387	203	95.67	2	203	9	207	1.4e-53	175.2	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
2919290388	269	78.03	99	269	23	125	5.1e-28	91.4	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2919290389	376	88.25	5	376	27	364	5.2e-76	250	COG0075	Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism protein PucG	383
2919290391	217	87.88	11	197	8	181	7.2e-38	124	COG4725	N6-adenosine-specific RNA methylase IME4	198
2919290392	432	98.31	8	424	6	413	0.0e+00	441.1	COG2733	Uncharacterized membrane-anchored protein YjiN, DUF445 family	415
2919290393	241	96.96	10	241	5	227	1.5e-59	195.1	COG1346	Putative effector of murein hydrolase	230
2919290394	119	88.28	1	119	5	117	9.5e-31	100.3	COG1380	Putative effector of murein hydrolase LrgA, UPF0299 family	128
2919290395	499	99.57	24	475	2	468	6.0e-119	392	COG0277	FAD/FMN-containing dehydrogenase	459
2919290396	301	97.34	18	301	2	294	2.0e-58	192.6	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919290397	282	97.91	1	282	6	286	8.2e-123	403.7	COG0788	Formyltetrahydrofolate hydrolase	287
2919290398	773	63.65	293	771	221	642	6.3e-113	371.6	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2919290399	312	80	62	303	58	293	1.7e-23	76.6	COG3016	Uncharacterized iron-regulated protein	295
2919290400	651	98.43	3	622	3	567	6.8e-129	425.2	COG3850	Signal transduction histidine kinase, nitrate/nitrite-specific	574
2919290401	240	97.16	15	238	3	207	3.2e-63	207.1	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2919290402	430	96.67	11	429	9	414	3.4e-113	372.6	COG2223	Nitrate/nitrite transporter NarK	417
2919290403	469	97.86	22	469	2	412	0.0e+00	441.1	COG2223	Nitrate/nitrite transporter NarK	417
2919290404	1265	99.92	1	1254	2	1242	0.0e+00	2081.8	COG5013	Nitrate reductase alpha subunit	1227
2919290405	507	98.44	1	507	1	505	0.0e+00	940.4	COG1140	Nitrate reductase beta subunit	513
2919290406	233	93.33	7	185	4	171	1.1e-51	169.1	COG2180	Nitrate reductase assembly protein NarJ, required for insertion of molybdenum cofactor	179
2919290407	244	97.81	5	232	3	225	8.8e-78	255.3	COG2181	Nitrate reductase gamma subunit	228
2919290408	313	41.85	72	308	165	300	1.3e-22	74.1	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
2919290409	225	96.63	1	202	4	204	3.0e-54	177.9	COG0288	Carbonic anhydrase	207
2919290410	815	86.63	14	603	90	750	5.0e-115	378.2	COG0209	Ribonucleotide reductase alpha subunit	696
2919290411	225	78.7	48	212	28	197	8.7e-15	48.4	COG0778	Nitroreductase	207
2919290413	194	72.49	30	190	12	148	2.7e-05	18	COG3945	Hemerythrin-like domain	189
2919290414	360	95.74	2	352	10	346	2.3e-56	185	COG3180	Uncharacterized membrane protein AbrB, regulator of aidB expression	352
2919290417	260	99.59	9	257	1	245	1.2e-62	205.1	COG1414	DNA-binding transcriptional regulator, IclR family	246
2919290418	336	98.17	4	334	3	270	2.2e-60	198.5	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
2919290419	325	97.81	1	324	6	317	4.8e-88	289.5	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2919290420	137	98.63	1	133	3	146	8.0e-10	33.5	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2919290421	340	96.37	1	338	12	330	2.2e-75	248.2	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2919290422	305	98.34	3	302	3	298	7.3e-68	223.6	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919290423	387	99.74	1	387	1	386	0.0e+00	530.8	COG1979	Alcohol dehydrogenase YqhD, Fe-dependent ADH family	384
2919290424	401	92.45	60	401	19	361	7.5e-44	144.1	COG4188	Predicted dienelactone hydrolase	365
2919290425	226	92.86	13	226	9	190	8.3e-41	134	COG0693	Putative intracellular protease/amidase	188
2919290426	706	93.7	3	690	51	809	0.0e+00	497.6	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
2919290427	382	94.81	11	381	8	354	7.7e-47	154.1	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2919290428	385	95.45	1	381	13	411	3.2e-68	224.8	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
2919290429	403	97.96	1	399	8	392	0.0e+00	444.9	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
2919290431	324	73.75	257	324	17	75	2.9e-13	42.7	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2919290433	388	91.15	10	387	29	368	2.4e-49	162	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
2919290434	232	97.76	2	229	5	266	5.0e-42	138.1	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2919290435	320	97.49	3	318	5	315	7.1e-83	272.3	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2919290436	312	98.33	4	312	4	297	6.0e-62	203.1	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
2919290437	315	98.34	8	315	1	296	1.5e-47	157	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919290438	155	99.35	1	155	2	154	8.1e-87	283.1	COG3558	Uncharacterized conserved protein, nuclear transport factor 2 (NTF2) superfamily	154
2919290439	202	88.04	8	200	15	198	3.8e-23	77.3	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2919290440	197	81.43	10	196	20	190	1.7e-30	100	COG5661	Predicted secreted Zn-dependent protease	210
2919290442	84	91.95	3	84	2	81	9.3e-34	109.7	COG4281	Acyl-CoA-binding protein	87
2919290443	306	64.16	4	284	2	266	9.7e-51	167	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
2919290444	353	98.79	7	329	4	329	1.4e-91	301.2	COG2423	Ornithine cyclodeaminase/archaeal alanine dehydrogenase, mu-crystallin family	330
2919290445	234	93.06	16	234	5	205	2.7e-20	66.9	COG0778	Nitroreductase	207
2919290447	390	91.22	4	380	30	372	4.5e-119	391.5	COG4324	Predicted aminopeptidase	376
2919290448	221	96.81	23	210	3	184	4.4e-80	261.7	COG2818	3-methyladenine DNA glycosylase Tag	188
2919290449	404	75.72	5	321	13	302	7.7e-11	36.5	COG0477	MFS family permease	338
2919290450	140	98.29	2	118	2	116	4.9e-36	117.6	COG1393	Arsenate reductase and related proteins, glutaredoxin family	117
2919290451	204	93.23	1	185	3	181	7.1e-60	195.8	COG3709	Ribose 1,5-bisphosphokinase PhnN	192
2919290453	260	96.23	21	256	9	238	4.4e-54	177.4	COG2188	DNA-binding transcriptional regulator, GntR family	236
2919290454	170	94.04	10	162	7	148	5.9e-48	156.5	COG3624	Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnG	151
2919290455	213	96.94	5	205	5	194	8.2e-56	182.6	COG3625	Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnH	196
2919290456	367	97	1	367	1	356	0.0e+00	597.8	COG3626	Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnI	367
2919290457	306	95.53	14	302	10	287	0.0e+00	552.9	COG3627	Alpha-D-ribose 1-methylphosphonate 5-phosphate C-P lyase	291
2919290458	153	82.1	7	149	21	153	1.5e-15	51.7	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2919290459	262	98.45	5	262	4	257	0.0e+00	453.4	COG4107	ABC-type phosphonate transport system, ATPase component	258
2919290460	244	95.32	7	243	5	228	4.6e-99	324.6	COG4778	Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL	235
2919290461	384	99.47	4	384	2	376	0.0e+00	481.7	COG3454	Alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase PhnM	377
2919290462	286	96.12	2	263	3	250	6.2e-97	317.8	COG3638	ABC-type phosphate/phosphonate transport system, ATPase component	258
2919290463	315	85.38	5	282	36	292	3.6e-87	286.3	COG3221	ABC-type phosphate/phosphonate transport system, periplasmic component	299
2919290464	268	94.37	2	268	16	283	3.1e-97	319.3	COG3639	ABC-type phosphate/phosphonate transport system, permease component	283
2919290465	186	96.24	1	178	6	184	2.7e-60	197.2	COG4341	Predicted HD phosphohydrolase	186
2919290467	338	96	14	338	7	318	1.4e-71	235.2	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
2919290468	374	8.62	327	367	168	195	3.6e-33	4.4	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
2919290468	374	56.62	46	301	40	223	3.6e-33	103.4	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
2919290469	153	88.61	1	145	10	149	4.8e-33	108.5	COG1522	DNA-binding transcriptional regulator, Lrp family	154
2919290470	322	96.01	11	302	8	296	4.7e-32	105.4	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2919290471	132	94.12	1	132	8	135	7.2e-29	94.6	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
2919290472	553	91.67	32	552	37	542	3.7e-124	408.9	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
2919290473	398	95.49	18	398	14	394	3.1e-105	346.5	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2919290474	284	98.49	21	281	5	265	1.7e-66	218.4	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2919290475	163	94.74	17	156	3	128	3.3e-25	82.8	COG1846	DNA-binding transcriptional regulator, MarR family	126
2919290476	785	88.8	1	391	3	351	1.1e-52	173.5	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2919290476	785	96.42	395	764	3	352	3.0e-113	372.5	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
2919290477	548	97.55	101	395	7	285	6.2e-94	308	COG2230	Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases	283
2919290478	363	98.12	33	361	4	316	1.8e-89	293.9	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2919290479	328	99.69	1	327	1	318	3.8e-89	293.1	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2919290480	415	94.52	1	409	10	423	9.6e-59	192.3	COG1541	Phenylacetate-coenzyme A ligase PaaK, adenylate-forming domain family	438
2919290481	270	99.16	6	248	3	237	6.4e-88	287.9	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2919290482	442	68.03	11	331	20	268	2.7e-09	30.4	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2919290483	358	95.67	23	350	11	319	7.5e-71	233	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2919290484	309	98.34	1	307	2	297	2.9e-63	208.2	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2919290485	274	99.21	19	272	3	254	2.8e-95	312.5	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2919290486	648	96.74	1	613	17	609	0.0e+00	436.7	COG1022	Long-chain acyl-CoA synthetase (AMP-forming)	613
2919290487	589	95.26	1	266	12	272	4.0e-59	194	COG3267	Type II secretory pathway, component ExeA (predicted ATPase)	269
2919290489	403	86.07	24	398	9	323	3.6e-44	145.3	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2919290490	241	94.95	13	232	9	215	5.7e-23	75.6	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2919290491	571	85.65	129	523	62	425	1.3e-104	345.1	COG0840	Methyl-accepting chemotaxis protein	408
2919290493	214	75.78	29	151	31	127	6.5e-10	32.9	COG3794	Plastocyanin	128
2919290494	778	63.5	280	778	221	641	3.6e-106	350.1	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2919290495	371	94.72	99	371	4	236	2.6e-69	225.1	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
2919290497	311	93.09	2	311	17	326	5.7e-23	75.1	COG0618	nanoRNase/pAp phosphatase, hydrolyzes c-di-AMP and oligoRNAs	332
2919290498	659	99.2	1	659	2	622	0.0e+00	818.2	COG0326	Molecular chaperone, HSP90 family	623
2919290500	201	38.17	6	154	123	214	4.2e-08	27.5	COG4083	Exosortase/Archaeosortase	239
2919290502	248	99.14	1	227	1	230	4.8e-66	216.5	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2919290503	352	98.21	12	352	4	332	3.8e-72	236.9	COG2334	Ser/Thr protein kinase RdoA involved in Cpx stress response, MazF antagonist	331
2919290505	478	66.6	11	386	3	315	8.3e-37	121.6	COG0515	Serine/threonine protein kinase	384
2919290506	252	93.67	66	250	10	157	2.6e-16	54.1	COG0639	Diadenosine tetraphosphatase ApaH/serine/threonine protein phosphatase, PP2A family	155
2919290507	128	97.52	3	118	3	120	7.3e-39	126.8	COG3759	Uncharacterized membrane protein	121
2919290508	138	96.5	1	138	5	142	8.5e-46	149.9	COG1764	Organic hydroperoxide reductase OsmC/OhrA	143
2919290509	154	78.95	27	153	5	109	9.3e-27	87.5	COG1846	DNA-binding transcriptional regulator, MarR family	126
2919290510	272	97.36	11	269	8	265	1.7e-57	188.8	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2919290511	282	86.02	1	282	1	283	3.4e-115	378.8	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
2919290512	529	97.01	1	529	8	558	0.0e+00	488.4	COG2303	Choline dehydrogenase or related flavoprotein	542
2919290514	450	32.76	1	165	44	100	3.4e-03	10.7	COG3576	Predicted flavin-nucleotide-binding protein, pyridoxine 5'-phosphate oxidase superfamily	173
2919290516	283	80	51	283	45	256	3.8e-22	72.7	COG1682	ABC-type polysaccharide/polyol phosphate export permease	263
2919290517	402	70.4	79	399	112	375	1.2e-55	183.2	COG4585	Signal transduction histidine kinase	365
2919290518	231	96.68	5	230	2	205	5.3e-56	183.5	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2919290519	468	96.12	74	408	10	331	5.6e-73	239.8	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2919290520	288	10.08	1	39	7	32	2.8e-64	3.7	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2919290520	288	77.52	58	288	53	252	2.8e-64	208.6	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2919290521	263	97.21	2	263	3	246	1.3e-84	277.7	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2919290522	147	97.35	1	147	5	151	3.4e-58	190.1	COG1513	Cyanate lyase	151
2919290523	256	95.83	1	255	8	237	3.3e-38	124.6	COG5343	Anti-sigma-K factor RskA	240
2919290524	188	93.01	11	188	6	178	6.1e-40	130.9	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2919290525	192	23.14	4	61	12	39	1.6e-03	5.3	COG4259	Uncharacterized protein	121
2919290525	192	28.1	148	191	4	37	1.6e-03	5.5	COG4259	Uncharacterized protein	121
2919290526	440	38.83	114	433	6	316	1.7e-40	132.9	COG1251	NAD(P)H-nitrite reductase, large subunit	793
2919290526	440	92.73	38	91	2	52	1.1e-21	70.1	COG1773	Rubredoxin	55
2919290527	385	95.74	12	384	10	391	3.8e-27	89.1	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2919290528	189	82.48	44	188	21	133	6.0e-11	33.3	COG1765	Uncharacterized OsmC-related protein	137
2919290529	303	98.26	2	288	4	285	2.5e-61	201.4	COG2897	3-mercaptopyruvate sulfurtransferase SseA, contains two rhodanese domains	285
2919290530	540	84.55	14	540	82	546	0.0e+00	463	COG3604	Transcriptional regulator containing GAF, AAA-type ATPase, and DNA-binding Fis domains	550
2919290531	302	52.44	9	157	56	141	1.4e-11	21.4	COG2010	Cytochrome c, mono- and diheme variants	150
2919290531	302	64.63	166	293	58	163	1.4e-11	16.1	COG2010	Cytochrome c, mono- and diheme variants	150
2919290532	326	33.56	6	138	87	135	7.3e-11	5.7	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2919290532	326	97.95	143	265	2	144	7.3e-11	33.5	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2919290533	249	93.78	25	246	7	202	7.8e-24	79.3	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2919290534	400	99.24	1	398	1	391	0.0e+00	577.7	COG0027	Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase)	394
2919290535	803	66.06	286	799	204	641	6.8e-116	381.8	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2919290536	311	99.35	1	307	3	306	2.5e-82	270.8	COG1131	ABC-type multidrug transport system, ATPase component	293
2919290537	378	93.99	199	377	10	181	9.2e-48	156.3	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2919290538	493	99.58	209	472	1	236	3.3e-61	200.6	COG0775	Nucleoside phosphorylase	234
2919290539	764	67.4	427	758	114	388	6.5e-25	81.4	COG0793	C-terminal processing protease CtpA/Prc, contains a PDZ domain	406
2919290540	902	99.13	12	901	3	800	0.0e+00	924.1	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
2919290541	367	96.12	15	348	12	333	5.3e-100	328.9	COG3520	Predicted component of the type VI protein secretion system	335
2919290542	624	99.84	1	624	1	620	0.0e+00	641.2	COG3519	Type VI protein secretion system component VasA	621
2919290543	174	94.9	11	171	4	152	3.7e-29	95.2	COG3518	Predicted component of the type VI protein secretion system	157
2919290544	261	91.21	2	261	17	265	8.7e-91	298.3	COG4455	Protein of avirulence locus involved in temperature-dependent protein secretion	273
2919290545	499	97.37	1	496	13	494	0.0e+00	781.1	COG3517	Predicted component of the type VI protein secretion system	495
2919290546	182	97.04	6	174	3	166	3.6e-66	216	COG3516	Predicted component of the type VI protein secretion system	169
2919290547	332	94.05	5	328	11	342	4.9e-41	133	COG3515	Predicted component of the type VI protein secretion system	346
2919290548	246	60.35	14	246	7	143	5.1e-29	94.6	COG3913	Uncharacterized protein	227
2919290549	1214	99.41	2	1214	7	1190	0.0e+00	997.8	COG3523	Type VI protein secretion system component VasK	1188
2919290550	447	65.83	257	424	66	196	2.1e-29	96.7	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
2919290550	447	89.02	13	272	26	260	1.5e-75	247.8	COG3455	Type VI protein secretion system component VasF	262
2919290551	444	100	1	444	1	446	0.0e+00	532.7	COG3522	Predicted component of the type VI protein secretion system	446
2919290552	192	78.88	3	170	12	138	1.9e-26	86.7	COG3521	Predicted component of the type VI protein secretion system	159
2919290553	262	94.49	7	261	5	261	4.1e-35	115.4	COG0631	Serine/threonine protein phosphatase PrpC	262
2919290554	705	49.77	3	370	20	234	9.9e-43	33	COG3456	Predicted component of the type VI protein secretion system, contains a FHA domain	430
2919290554	705	63.89	367	702	151	426	9.9e-43	114	COG3456	Predicted component of the type VI protein secretion system, contains a FHA domain	430
2919290557	654	72.55	10	443	3	343	3.3e-34	112.8	COG0515	Serine/threonine protein kinase	384
2919290558	160	92.41	1	159	1	146	2.4e-29	96.3	COG3157	Type VI protein secretion system component Hcp (secreted cytotoxin)	162
2919290559	108	12.8	1	80	13	86	3.3e-16	53	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
2919290560	396	64.88	1	387	120	494	3.2e-126	416.1	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
2919290562	1556	5.96	877	949	240	290	5.3e-60	6	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
2919290562	1556	8.76	366	466	25	99	5.3e-60	20.5	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
2919290562	1556	13.79	117	328	238	355	5.3e-60	5.3	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
2919290562	1556	14.25	622	753	74	195	5.3e-60	47.7	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
2919290562	1556	20.21	466	642	10	182	5.3e-60	35.9	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
2919290562	1556	40.3	974	1548	392	736	5.3e-60	98.3	COG3209	Uncharacterized conserved protein RhaS, contains 28 RHS repeats	796
2919290564	691	64.71	214	688	216	644	7.6e-120	394.8	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2919290565	425	98.68	43	425	1	375	6.5e-49	160.7	COG3174	Uncharacterized membrane protein, DUF4010 family	371
2919290566	472	72.31	1	410	24	399	0.0e+00	443.3	COG0513	Superfamily II DNA and RNA helicase	513
2919290567	230	56.06	105	229	80	264	3.6e-26	38.8	COG0666	Ankyrin repeat	235
2919290567	230	61.82	32	177	77	280	3.6e-26	57	COG0666	Ankyrin repeat	235
2919290568	164	95.74	24	162	4	138	1.8e-34	112.8	COG3193	Uncharacterized conserved protein GlcG, DUF336 family	141
2919290569	210	96.53	6	206	4	198	1.4e-69	227.6	COG4566	Two-component response regulator, FixJ family, consists of REC and HTH domains	202
2919290570	514	62.69	164	513	143	389	5.9e-48	158	COG0642	Signal transduction histidine kinase	336
2919290571	316	93.11	13	308	12	295	2.5e-82	270.4	COG0053	Divalent metal cation (Fe/Co/Zn/Cd) transporter	304
2919290572	152	97.93	1	145	2	143	3.7e-59	193.4	COG1490	D-Tyr-tRNAtyr deacylase	145
2919290573	148	96.86	1	148	4	157	3.9e-34	112.9	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2919290574	443	51.7	236	441	10	207	1.6e-17	13.4	COG0477	MFS family permease	338
2919290574	443	71.54	35	275	5	278	1.6e-17	43.9	COG0477	MFS family permease	338
2919290575	248	95.37	1	248	8	254	3.4e-35	115.8	COG0730	Uncharacterized membrane protein YfcA	258
2919290576	152	86.36	17	152	20	152	1.6e-41	135.5	COG0319	ssRNA-specific RNase YbeY, 16S rRNA maturation enzyme	153
2919290577	318	94.12	3	318	15	334	4.0e-129	424.5	COG1702	Phosphate starvation-inducible protein PhoH, predicted ATPase	348
2919290578	191	99.5	1	190	1	200	4.6e-64	209.7	COG0632	Holliday junction resolvasome RuvABC DNA-binding subunit	201
2919290580	353	99.1	13	345	3	331	0.0e+00	533.5	COG2255	Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit	332
2919290581	600	74.73	2	238	48	257	5.0e-48	158.4	COG3000	Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily	271
2919290581	600	93.87	355	574	11	209	9.9e-26	85.1	COG3714	Uncharacterized membrane protein YhhN	212
2919290582	389	95.15	6	382	10	362	7.2e-70	229.4	COG3616	D-serine deaminase, pyridoxal phosphate-dependent	368
2919290583	213	91.87	2	209	3	194	4.3e-55	180.7	COG0406	Broad specificity phosphatase PhoE	208
2919290585	327	81.49	44	313	2	252	6.2e-70	229.7	COG0037	tRNA(Ile)-lysidine synthase TilS/MesJ	298
2919290586	127	84.3	11	125	3	104	4.8e-21	69.2	COG1539	Dihydroneopterin aldolase	121
2919290587	264	97.76	8	258	6	267	2.1e-42	139.6	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2919290588	369	95.95	10	359	5	359	8.3e-89	292	COG1565	SAM-dependent methyltransferase, MidA family	370
2919290590	458	95.52	1	458	15	483	0.0e+00	501.6	COG0380	Trehalose-6-phosphate synthase	486
2919290591	601	95.51	12	597	22	617	3.0e-93	307.4	COG3387	Glucoamylase (glucan-1,4-alpha-glucosidase), GH15 family	612
2919290592	245	89.55	5	245	18	257	2.1e-50	165.6	COG1877	Trehalose-6-phosphatase	266
2919290593	145	28.52	38	145	43	129	1.0e-27	91.7	COG3118	Negative regulator of GroEL, contains thioredoxin-like and TPR-like domains	304
2919290594	157	91.67	22	157	10	141	1.3e-21	71.5	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
2919290596	282	93.97	2	280	5	269	7.8e-97	317.8	COG3220	Uncharacterized conserved protein, UPF0276 family	282
2919290597	97	87.5	1	96	12	102	1.7e-35	115.5	COG5572	Uncharacterized membrane protein	104
2919290598	209	94.09	8	186	6	180	1.4e-38	126.5	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2919290599	213	100	1	213	1	213	1.3e-55	182.7	COG4944	Uncharacterized protein	213
2919290600	152	77.78	2	147	14	160	2.4e-16	54.2	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
2919290601	419	90.12	1	391	23	396	5.3e-91	299.9	COG0617	tRNA nucleotidyltransferase/poly(A) polymerase	412
2919290602	151	36.82	22	150	43	123	5.9e-04	13.7	COG3599	Cell division septum initiation DivIVA, interacts with FtsZ, MinD and other proteins	212
2919290604	230	94.88	3	226	4	207	9.0e-39	127.5	COG0625	Glutathione S-transferase	211
2919290605	190	97.38	1	189	3	188	4.8e-37	121.6	COG0212	5-formyltetrahydrofolate cyclo-ligase	191
2919290606	661	97.36	341	640	2	296	4.5e-52	170.5	COG0741	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)	296
2919290608	310	84.62	7	280	14	233	7.4e-38	124.6	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2919290609	129	99.26	1	129	2	135	1.9e-46	151.5	COG1869	D-ribose pyranose/furanose isomerase RbsD	135
2919290610	314	97.47	8	305	2	309	5.3e-72	236.5	COG0524	Sugar or nucleoside kinase, ribokinase family	311
2919290611	340	99.4	2	336	1	332	1.0e-120	397.2	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
2919290612	330	96.55	18	330	8	315	1.5e-88	290.9	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
2919290613	553	34.73	353	536	327	500	0.0e+00	194.7	COG1129	ABC-type sugar transport system, ATPase component	500
2919290613	553	63.47	7	348	5	322	0.0e+00	360.9	COG1129	ABC-type sugar transport system, ATPase component	500
2919290614	317	93.88	1	317	8	314	2.4e-77	254.2	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
2919290615	560	96.83	14	560	7	556	2.1e-127	419.9	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2919290617	299	56.95	58	297	18	185	1.1e-11	38.9	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2919290619	279	86.25	11	277	29	279	1.5e-105	346.5	COG3186	Phenylalanine-4-hydroxylase	291
2919290620	322	97.18	1	320	8	317	5.4e-75	246.5	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2919290621	370	97.8	3	370	6	360	0.0e+00	430.2	COG3185	4-hydroxyphenylpyruvate dioxygenase and related hemolysins	363
2919290622	329	85.51	67	318	39	280	2.1e-26	86.2	COG5380	Lipase chaperone LimK	283
2919290623	313	83.62	8	310	58	348	1.1e-64	213	COG1075	Triacylglycerol esterase/lipase EstA, alpha/beta hydrolase fold	336
2919290624	160	95.57	4	160	6	156	1.5e-41	136.2	COG1522	DNA-binding transcriptional regulator, Lrp family	154
2919290625	246	59.36	41	213	46	156	1.1e-08	29.3	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
2919290626	294	93.17	8	294	12	284	1.1e-91	301	COG4535	Mg2+ and Co2+ transporter CorC, contains CBS pair and CorC-HlyC domains	293
2919290627	544	96.54	2	542	15	516	6.4e-100	329	COG0815	Apolipoprotein N-acyltransferase	518
2919290628	173	89.19	11	165	16	147	7.4e-37	120.5	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
2919290629	407	99.52	3	406	2	413	3.8e-130	428.5	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
2919290630	305	95.02	1	295	1	286	4.2e-47	155.4	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919290631	358	93.85	8	358	19	354	1.8e-105	346.9	COG0252	L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D	351
2919290632	301	97.65	1	291	5	295	0.0e+00	534.9	COG0752	Glycyl-tRNA synthetase, alpha subunit	298
2919290633	713	99.86	1	713	1	690	0.0e+00	727.8	COG0751	Glycyl-tRNA synthetase, beta subunit	691
2919290634	201	80.87	1	180	6	153	6.9e-42	137	COG0241	Histidinol phosphatase or a related phosphatase	181
2919290635	261	79.31	14	258	31	237	3.6e-44	145	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
2919290636	267	93.39	26	267	10	221	1.6e-49	162.6	COG1451	Predicted metal-dependent hydrolase	223
2919290637	138	86.84	13	138	7	105	9.4e-15	48	COG0607	Rhodanese-related sulfurtransferase	110
2919290638	162	79.72	1	162	54	281	4.6e-29	92	COG1652	Nucleoid-associated protein YgaU, contains BON and LysM domains	269
2919290639	255	99.21	2	252	2	252	8.3e-47	153.9	COG1521	Pantothenate kinase type III	251
2919290640	258	65.49	12	256	102	342	2.0e-05	18.6	COG0457	Tetratricopeptide (TPR) repeat	291
2919290641	220	89.47	1	216	9	195	1.4e-23	78.7	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2919290642	197	87.04	20	132	4	97	1.8e-07	23	COG3937	Polyhydroxyalkanoate synthesis regulator phasin	108
2919290643	661	54.85	1	175	8	154	6.3e-60	26.2	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2919290643	661	94.4	374	619	4	256	6.3e-60	171.2	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2919290644	362	99.14	1	351	3	349	0.0e+00	526.7	COG1088	dTDP-D-glucose 4,6-dehydratase	340
2919290645	296	99.29	1	296	1	280	2.8e-99	325.9	COG1091	dTDP-4-dehydrorhamnose reductase	281
2919290646	294	99.31	4	292	1	289	6.1e-124	406.8	COG1209	dTDP-glucose pyrophosphorylase	286
2919290647	181	97.74	1	176	5	177	2.4e-75	246.1	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase or related enzyme	173
2919290649	573	95.28	85	569	24	507	0.0e+00	587.1	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
2919290650	418	99.5	1	418	1	396	1.7e-114	376.5	COG1459	Type II secretory pathway, component PulF	397
2919290651	151	96.15	14	150	5	154	6.9e-26	85.7	COG2165	Type II secretory pathway, pseudopilin PulG	149
2919290652	149	78.8	1	144	6	150	9.8e-14	43.8	COG4970	Tfp pilus assembly protein FimT	181
2919290653	133	41.03	1	121	4	67	1.2e-08	29.9	COG2165	Type II secretory pathway, pseudopilin PulG	149
2919290655	269	17.9	1	71	8	65	3.1e-07	17.9	COG3156	Type II secretory pathway, component PulK	323
2919290655	269	21.91	87	250	180	250	3.1e-07	8.9	COG3156	Type II secretory pathway, component PulK	323
2919290656	441	45.67	189	359	87	181	5.7e-05	15.9	COG3166	Tfp pilus assembly protein PilN	206
2919290659	790	91.88	37	790	26	591	1.5e-109	356.2	COG1450	Type II secretory pathway component GspD/PulD (secretin)	587
2919290663	173	65.66	1	173	92	265	8.3e-30	98	COG1682	ABC-type polysaccharide/polyol phosphate export permease	263
2919290664	425	98.41	3	247	2	248	8.8e-87	284.8	COG1134	ABC-type polysaccharide/polyol phosphate transport system, ATPase component	249
2919290665	323	52.33	62	319	28	173	6.0e-07	24.1	COG0500	SAM-dependent methyltransferase	257
2919290666	289	77.06	4	282	29	243	1.6e-06	22.7	COG0500	SAM-dependent methyltransferase	257
2919290667	433	17.07	14	67	2	50	1.9e-61	7.9	COG4976	Predicted methyltransferase, contains TPR repeat	287
2919290667	433	18.12	57	129	13	64	1.9e-61	12.8	COG4976	Predicted methyltransferase, contains TPR repeat	287
2919290667	433	93.38	149	433	18	285	1.9e-61	183.8	COG4976	Predicted methyltransferase, contains TPR repeat	287
2919290668	1249	64.75	4	203	59	216	9.0e-20	64.4	COG2227	2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase	243
2919290668	1249	74.76	523	771	7	240	4.2e-31	101.9	COG1216	Glycosyltransferase, GT2 family	305
2919290668	1249	81.42	799	1136	11	343	2.4e-10	33.9	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2919290670	367	96.63	1	338	9	323	1.1e-44	147.2	COG0472	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase	319
2919290671	296	99.62	27	295	1	264	2.7e-100	329	COG0548	Acetylglutamate kinase	265
2919290672	230	99.14	1	229	1	230	6.0e-73	239.1	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2919290673	498	81.47	136	498	67	387	1.1e-57	189.7	COG0642	Signal transduction histidine kinase	336
2919290674	220	94.74	18	220	6	203	4.0e-18	61	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2919290675	242	96.65	8	221	6	207	4.9e-16	54.2	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2919290676	598	97.49	16	464	7	395	5.2e-99	325.1	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2919290677	145	49.09	1	145	84	164	2.0e-14	47	COG4731	Uncharacterized conserved protein, DUF2147 family	162
2919290678	800	23.71	340	488	210	287	6.2e-90	19.9	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
2919290678	800	83.02	483	775	23	242	2.0e-36	118.7	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2919290678	800	96.35	4	345	2	318	6.2e-90	273.9	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
2919290679	169	71.63	15	161	16	116	5.6e-08	26.6	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
2919290680	399	99.49	6	399	2	393	3.0e-127	419	COG0183	Acetyl-CoA acetyltransferase	392
2919290681	295	93.59	3	279	14	276	2.2e-51	168.8	COG4757	Predicted alpha/beta hydrolase	281
2919290682	286	44.14	12	286	155	282	1.0e-04	13.9	COG1946	Acyl-CoA thioesterase	289
2919290683	258	99.25	2	255	3	265	3.0e-70	230.7	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2919290685	249	84.21	44	249	7	182	2.0e-24	81.5	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2919290686	309	97.76	17	265	5	266	3.3e-66	217.6	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2919290687	537	99.24	13	537	4	525	0.0e+00	478.1	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component	526
2919290688	376	93.41	107	274	4	159	7.2e-45	146.4	COG4335	3-methyladenine DNA glycosylase AlkC	167
2919290689	392	96.99	1	390	5	391	1.2e-105	348	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2919290690	269	95.09	5	265	14	265	4.2e-63	207.2	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2919290691	644	99.69	1	637	2	645	0.0e+00	734.9	COG4770	Acetyl/propionyl-CoA carboxylase, alpha subunit	645
2919290692	390	96.74	3	390	7	392	1.5e-109	360.8	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2919290693	298	98.99	6	295	3	297	1.3e-57	188.9	COG3246	Uncharacterized conserved protein, DUF849 family	298
2919290695	723	95.47	5	303	11	263	7.3e-48	157.6	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2919290695	723	98.18	323	663	4	326	1.3e-94	311.1	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
2919290696	401	99.75	1	401	1	393	1.3e-124	410.5	COG0183	Acetyl-CoA acetyltransferase	392
2919290698	387	96.99	3	387	7	393	8.3e-129	424.3	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2919290699	388	96.72	13	388	7	360	9.2e-51	167.1	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2919290700	618	97.55	9	618	10	607	0.0e+00	566.2	COG1022	Long-chain acyl-CoA synthetase (AMP-forming)	613
2919290702	272	99.58	18	254	2	237	1.1e-95	313.4	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2919290703	279	99.61	2	260	2	254	6.2e-93	304.8	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2919290704	358	96.59	17	333	8	319	1.4e-84	278.2	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2919290705	291	98.67	1	290	4	300	5.3e-71	233.8	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2919290706	265	95.09	1	265	6	257	7.0e-62	203.3	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2919290707	161	86.52	16	161	15	136	3.5e-23	76	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
2919290708	186	78.08	45	178	13	126	5.1e-16	52.6	COG1664	Cytoskeletal protein CcmA, bactofilin family	146
2919290709	140	77.71	6	139	11	132	4.1e-42	137.5	COG1607	Acyl-CoA hydrolase	157
2919290710	614	99.8	109	607	1	496	0.0e+00	739.5	COG5265	ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components	497
2919290711	310	99.08	1	310	2	325	2.5e-80	264	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
2919290712	110	85.44	4	104	5	92	2.4e-15	50.6	COG1694	NTP pyrophosphatase, house-cleaning of non-canonical NTPs	102
2919290713	345	98.8	1	342	2	329	1.4e-89	294.8	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
2919290714	432	98.68	51	431	3	376	1.1e-109	360.6	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
2919290715	187	83.62	24	187	14	161	4.6e-30	98.4	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
2919290716	310	97.67	1	310	1	294	3.4e-49	162.4	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919290717	298	96.11	1	278	9	280	5.9e-57	187.3	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2919290718	299	96.11	1	273	6	277	5.6e-51	167.6	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2919290719	252	92.11	5	241	17	226	1.2e-60	199.1	COG0765	ABC-type amino acid transport system, permease component	222
2919290720	221	92.98	1	221	15	226	3.4e-63	207.6	COG0765	ABC-type amino acid transport system, permease component	222
2919290721	245	99.17	1	243	2	241	8.4e-108	353.2	COG1126	ABC-type polar amino acid transport system, ATPase component	240
2919290722	306	97.16	9	290	5	278	2.8e-50	165.1	COG1737	DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains	281
2919290723	393	95.93	16	391	12	412	3.9e-56	184.9	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
2919290724	329	97.49	7	328	8	318	1.9e-89	294	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2919290725	346	99.13	4	346	3	343	0.0e+00	506.5	COG0418	Dihydroorotase	344
2919290727	292	92.31	1	292	21	308	1.6e-70	232.2	COG0501	Zn-dependent protease with chaperone function	302
2919290728	524	90.59	78	516	41	425	2.6e-107	354.1	COG0840	Methyl-accepting chemotaxis protein	408
2919290729	354	97.23	8	346	8	323	1.4e-55	182.7	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
2919290730	447	98.98	35	447	4	392	1.6e-126	416.6	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
2919290731	180	86.28	2	177	16	210	5.6e-43	137.1	COG1738	Uncharacterized PurR-regulated membrane protein YhhQ, DUF165 family	233
2919290732	572	96.5	6	569	14	482	0.0e+00	508.1	COG2509	Uncharacterized FAD-dependent dehydrogenase	486
2919290733	338	94.14	20	336	14	318	1.7e-43	143.2	COG0392	Uncharacterized membrane protein YbhN, UPF0104 family	322
2919290734	416	83.3	1	399	59	462	3.7e-78	257.5	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
2919290735	257	97.28	6	257	4	253	1.3e-69	228.7	COG3568	Metal-dependent hydrolase, endonuclease/exonuclease/phosphatase family	259
2919290736	305	99.01	2	300	3	301	1.4e-115	379.6	COG0031	Cysteine synthase	300
2919290737	362	98.83	13	359	4	340	8.0e-99	325	COG0430	RNA 3'-terminal phosphate cyclase	341
2919290738	407	98.92	11	407	6	463	2.8e-102	336.9	COG1690	RNA-splicing ligase RtcB, repairs tRNA damage	432
2919290741	381	17.61	301	359	245	297	2.6e-27	19.6	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
2919290741	381	34.88	3	143	26	130	2.6e-27	8.7	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
2919290741	381	58.14	144	317	25	199	2.6e-27	73.2	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
2919290743	542	98.31	1	542	3	524	0.0e+00	802.1	COG4650	Sigma54-dependent transcription regulator containing an AAA-type ATPase domain and a DNA-binding domain	531
2919290746	393	85.21	243	385	3	146	2.4e-22	73.1	COG4639	Predicted kinase	168
2919290748	407	78.53	84	401	61	305	2.1e-27	90.2	COG0501	Zn-dependent protease with chaperone function	302
2919290749	421	97.53	12	420	7	361	2.7e-56	181.1	COG4269	Uncharacterized membrane protein YjgN, DUF898 family	364
2919290750	264	29.27	9	97	3	74	1.1e-39	42.3	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
2919290750	264	52.03	123	264	109	236	1.1e-39	86.5	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
2919290751	565	77.33	9	218	14	146	4.3e-16	52.8	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2919290751	565	84.23	284	550	13	231	4.1e-33	108.3	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2919290752	400	96.96	1	387	10	392	0.0e+00	436.3	COG2814	Predicted arabinose efflux permease, MFS family	394
2919290753	294	97.67	3	294	2	295	3.2e-71	234.7	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919290755	234	96.74	21	233	3	210	3.2e-59	194.3	COG0625	Glutathione S-transferase	211
2919290756	293	99.63	3	288	1	270	1.6e-94	310.4	COG0253	Diaminopimelate epimerase	272
2919290757	229	97.71	5	229	4	216	1.3e-50	166.3	COG3159	Uncharacterized conserved protein YigA, DUF484 family	218
2919290758	325	98.66	6	323	5	299	4.8e-107	351.9	COG4973	Site-specific recombinase XerC	299
2919290759	226	85.8	6	225	14	164	5.6e-21	67	COG0681	Signal peptidase I	166
2919290760	551	88.24	87	513	51	425	6.7e-105	345.8	COG0840	Methyl-accepting chemotaxis protein	408
2919290761	175	89.7	9	173	9	156	2.4e-40	131.8	COG0835	Chemotaxis signal transduction protein	165
2919290762	411	98.73	4	409	2	389	2.3e-103	340	COG1092	23S rRNA G2069 N7-methylase RlmK or C1962 C5-methylase RlmI	393
2919290763	353	98.47	4	353	1	321	6.0e-109	354.4	COG0523	GTPase, G3E family	323
2919290764	265	99.17	146	265	1	119	8.3e-38	123.3	COG1734	RNA polymerase-binding transcription factor DksA	120
2919290765	579	36.75	333	397	43	85	5.0e-04	8	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
2919290765	579	72.65	481	575	16	100	5.0e-04	3.7	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
2919290766	188	97.75	10	188	2	175	2.3e-84	275.6	COG5405	ATP-dependent protease HslVU (ClpYQ), peptidase subunit	178
2919290767	441	100	1	441	1	444	0.0e+00	714.9	COG1220	ATP-dependent protease HslVU (ClpYQ), ATPase subunit	444
2919290768	142	98.63	1	142	1	144	8.5e-44	143.1	COG2001	MraZ, DNA-binding transcriptional regulator and inhibitor of RsmH methyltransferase activity	146
2919290769	308	98.41	1	307	4	313	1.5e-106	350.8	COG0275	16S rRNA C1402 N4-methylase RsmH	314
2919290770	109	78.85	1	97	19	100	8.2e-23	74.7	COG3116	Cell division protein FtsL, interacts with FtsB, FtsL and FtsQ	105
2919290771	577	97.63	9	563	14	630	0.0e+00	434.9	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
2919290772	504	97.52	5	498	12	483	0.0e+00	448.8	COG0769	UDP-N-acetylmuramyl tripeptide synthase	475
2919290773	483	98.68	7	461	5	452	2.6e-128	422.5	COG0770	UDP-N-acetylmuramyl pentapeptide synthase	451
2919290774	392	98.77	23	392	2	323	2.6e-111	365.6	COG0472	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase	319
2919290775	682	41.11	429	672	264	448	1.3e-129	199.8	COG0771	UDP-N-acetylmuramoylalanine-D-glutamate ligase	448
2919290775	682	49.56	142	413	5	227	1.3e-129	225.8	COG0771	UDP-N-acetylmuramoylalanine-D-glutamate ligase	448
2919290776	422	95.29	35	421	13	376	8.4e-118	387.4	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
2919290777	354	98.88	5	354	2	355	1.8e-111	367	COG0707	UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase	357
2919290778	477	99.13	1	466	4	460	0.0e+00	556.2	COG0773	UDP-N-acetylmuramate-alanine ligase	459
2919290779	329	99.06	12	319	3	317	1.0e-99	327.8	COG1181	D-alanine-D-alanine ligase and related ATP-grasp enzymes	317
2919290780	267	84.5	4	259	32	260	9.1e-40	130.7	COG1589	Cell division septal protein FtsQ	269
2919290781	409	86.87	1	400	4	380	0.0e+00	446.4	COG0849	Cell division ATPase FtsA	418
2919290782	413	93.1	3	345	3	326	9.8e-120	393.9	COG0206	Cell division GTPase FtsZ	338
2919290783	593	81.88	111	519	78	425	8.8e-106	349	COG0840	Methyl-accepting chemotaxis protein	408
2919290784	307	98.67	1	305	2	298	2.2e-121	398.8	COG0774	UDP-3-O-acyl-N-acetylglucosamine deacetylase	300
2919290787	634	99.31	138	599	2	432	0.0e+00	735.6	COG0422	Thiamine biosynthesis protein ThiC	432
2919290788	549	91.76	69	517	36	425	1.0e-110	364.1	COG0840	Methyl-accepting chemotaxis protein	408
2919290789	462	88.39	3	462	59	507	0.0e+00	567	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
2919290790	726	92.05	4	694	32	598	0.0e+00	492.9	COG1450	Type II secretory pathway component GspD/PulD (secretin)	587
2919290792	181	79.01	1	160	23	165	4.1e-18	59.9	COG3149	Type II secretory pathway, component PulM	181
2919290793	428	18.97	266	389	240	313	1.4e-11	12	COG3297	Type II secretory pathway, component PulL	390
2919290793	428	34.62	1	252	6	140	1.4e-11	25.7	COG3297	Type II secretory pathway, component PulL	390
2919290794	359	92.28	32	344	6	304	2.2e-35	114	COG3156	Type II secretory pathway, component PulK	323
2919290795	221	81.09	2	185	5	167	1.2e-16	55.2	COG4795	Type II secretory pathway, component PulJ	194
2919290796	124	48.72	2	119	8	83	2.9e-10	35.1	COG2165	Type II secretory pathway, pseudopilin PulG	149
2919290797	171	83.97	5	167	6	136	1.9e-12	42	COG2165	Type II secretory pathway, pseudopilin PulG	149
2919290798	154	96.15	13	153	7	156	7.8e-32	105.1	COG2165	Type II secretory pathway, pseudopilin PulG	149
2919290800	197	78.95	8	195	2	166	1.4e-18	61.5	COG0406	Broad specificity phosphatase PhoE	208
2919290801	268	97.99	1	268	4	247	2.2e-56	185.7	COG0368	Cobalamin synthase	246
2919290802	519	97.98	4	348	7	345	3.8e-130	428	COG1171	Threonine dehydratase	347
2919290804	149	97.81	1	148	2	135	5.7e-38	124.1	COG1765	Uncharacterized OsmC-related protein	137
2919290805	205	98.55	1	205	1	204	1.8e-61	201.5	COG2941	Demethoxyubiquinone hydroxylase, CLK1/Coq7/Cat5 family	204
2919290806	348	100	1	348	1	360	7.5e-45	147.4	COG3203	Outer membrane protein (porin)	354
2919290807	526	92.73	1	523	21	556	1.3e-93	309	COG0747	ABC-type transport system, periplasmic component	556
2919290808	326	99.69	1	322	1	317	7.8e-110	361.4	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2919290809	405	97.2	11	402	8	389	4.5e-121	398.7	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
2919290810	527	97.06	1	527	12	572	1.0e-95	316	COG0747	ABC-type transport system, periplasmic component	556
2919290811	303	91.28	2	303	25	296	2.1e-102	336.2	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2919290812	328	99.38	3	318	1	323	2.1e-126	415.5	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
2919290813	337	97.19	8	325	2	312	6.0e-119	391.1	COG4608	ABC-type oligopeptide transport system, ATPase component	309
2919290814	309	98.01	1	298	1	295	6.5e-62	204.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919290815	708	34.65	578	701	158	271	4.6e-106	26.4	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
2919290815	708	86.93	298	608	3	288	4.6e-106	323.9	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
2919290815	708	95.85	5	287	6	259	7.9e-59	193.5	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2919290816	391	99.49	1	390	1	392	3.1e-117	386	COG0183	Acetyl-CoA acetyltransferase	392
2919290817	398	98.75	1	398	1	394	3.9e-87	287.1	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2919290818	377	92.73	1	373	1	370	1.5e-71	235.7	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2919290819	280	98.11	1	260	6	265	2.5e-70	231.1	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2919290820	416	98.5	5	410	6	400	0.0e+00	446.8	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2919290821	335	97.81	9	333	5	316	5.4e-83	272.8	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2919290822	337	98.43	14	335	4	317	2.8e-87	286.8	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2919290823	521	97.18	6	520	9	560	9.9e-100	328.5	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2919290824	38	13.79	2	38	2	37	1.5e-08	28.4	COG2086	Electron transfer flavoprotein, alpha and beta subunits	260
2919290825	34	10.69	1	34	282	315	7.3e-15	49.7	COG2025	Electron transfer flavoprotein, alpha subunit	313
2919290826	327	97.81	7	326	6	317	4.2e-86	283.1	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2919290827	281	98.23	1	280	5	281	1.7e-78	257.7	COG1737	DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains	281
2919290828	342	97.01	44	339	7	298	1.5e-76	251.5	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
2919290829	749	97.24	171	741	9	537	0.0e+00	457.7	COG1178	ABC-type Fe3+ transport system, permease component	540
2919290830	360	98.02	3	351	5	350	1.7e-119	393.3	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
2919290831	316	99.01	5	315	2	302	3.6e-98	323.1	COG0176	Transaldolase	239
2919290833	465	84.26	114	465	56	387	6.3e-59	194.5	COG0642	Signal transduction histidine kinase	336
2919290834	238	98.71	2	238	2	230	2.5e-66	217.4	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2919290835	416	98.65	1	416	1	437	4.4e-48	159	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
2919290836	394	99.3	1	394	4	430	1.6e-59	196.5	COG4580	Maltoporin (phage lambda and maltose receptor)	429
2919290837	292	94.63	1	290	8	289	1.5e-73	241.9	COG1175	ABC-type sugar transport system, permease component	295
2919290838	289	97.17	2	288	9	283	3.0e-78	257.2	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
2919290839	353	99.43	2	347	2	349	0.0e+00	453	COG3839	ABC-type sugar transport system, ATPase component	338
2919290840	325	97.19	1	321	7	317	1.4e-106	350.3	COG0837	Glucokinase	320
2919290841	142	99.32	14	137	2	146	5.2e-25	83.6	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2919290842	334	97.12	22	333	10	312	2.0e-108	355.7	COG3958	Transketolase, C-terminal subunit	312
2919290843	284	97.94	2	245	6	243	3.3e-94	308.8	COG3959	Transketolase, N-terminal subunit	243
2919290844	419	97.89	46	419	1	371	1.8e-121	400	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
2919290845	171	86.44	1	170	17	169	1.6e-27	90.3	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
2919290846	328	97.29	2	328	4	326	8.4e-111	364.5	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
2919290847	249	99.25	1	248	2	267	1.7e-69	228.6	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2919290848	294	98.01	5	294	3	297	3.5e-61	201.8	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919290849	484	98.56	1	483	7	485	0.0e+00	596	COG0364	Glucose-6-phosphate 1-dehydrogenase	483
2919290850	522	96.69	45	511	4	441	0.0e+00	538.7	COG0166	Glucose-6-phosphate isomerase	446
2919290851	413	96.91	3	408	5	380	7.4e-101	331.8	COG2942	Mannose or cellobiose epimerase, N-acyl-D-glucosamine 2-epimerase family	388
2919290852	163	20.11	15	59	109	146	8.7e-14	3.2	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
2919290852	163	49.74	51	160	79	172	8.7e-14	41.8	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
2919290853	309	91.91	5	307	25	308	2.9e-71	234	COG3386	Sugar lactone lactonase YvrE	307
2919290854	589	98.44	2	589	5	573	0.0e+00	620	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
2919290855	209	95.73	1	207	7	208	3.7e-75	246	COG0800	2-keto-3-deoxy-6-phosphogluconate aldolase	211
2919290856	99	65.28	4	96	6	99	7.6e-21	64.8	COG3152	Uncharacterized membrane protein YhaH, DUF805 family	125
2919290857	549	98.73	1	537	1	543	0.0e+00	603.2	COG0459	Chaperonin GroEL (HSP60 family)	524
2919290858	96	98.96	1	96	1	95	3.1e-41	133.8	COG0234	Co-chaperonin GroES (HSP10)	96
2919290859	311	95.13	3	310	4	335	3.4e-82	266.4	COG0002	N-acetyl-gamma-glutamylphosphate reductase	349
2919290860	295	96.68	4	294	1	291	1.8e-53	176.4	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919290861	208	87.78	15	208	12	169	1.5e-43	142.8	COG0723	Rieske Fe-S protein	177
2919290862	459	59.27	122	459	220	545	2.0e-117	387.6	COG3604	Transcriptional regulator containing GAF, AAA-type ATPase, and DNA-binding Fis domains	550
2919290863	235	90.91	25	232	13	202	5.1e-19	63.8	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2919290865	449	97.82	20	449	5	452	9.2e-114	374.8	COG0493	NADPH-dependent glutamate synthase beta chain or related oxidoreductase	457
2919290866	437	95.89	337	408	3	72	8.3e-13	41.8	COG1146	NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit	68
2919290866	437	99.03	3	324	2	308	2.9e-81	267	COG0167	Dihydroorotate dehydrogenase	310
2919290867	485	92.63	7	485	22	486	0.0e+00	502.1	COG1953	Cytosine/uracil/thiamine/allantoin permease	497
2919290868	483	98.84	3	452	3	428	1.2e-123	407.2	COG0044	Dihydroorotase or related cyclic amidohydrolase	430
2919290869	418	98.8	15	418	3	415	1.5e-57	189.7	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
2919290870	345	92.47	195	344	5	139	1.5e-27	89.6	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
2919290870	345	96.53	1	174	4	170	2.3e-33	109.3	COG1056	Nicotinamide mononucleotide adenylyltransferase	172
2919290871	566	89.21	1	272	2	249	1.7e-43	142.5	COG0388	Predicted amidohydrolase	274
2919290871	566	95.26	276	558	9	269	2.5e-69	227.5	COG0171	NH3-dependent NAD+ synthetase	268
2919290872	399	90.24	1	399	9	378	7.3e-102	335.3	COG1488	Nicotinic acid phosphoribosyltransferase	405
2919290873	280	95.15	1	280	4	199	4.1e-21	68.3	COG1335	Nicotinamidase-related amidase	205
2919290874	225	93.84	2	174	8	144	1.3e-25	83.4	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
2919290875	413	93.44	233	409	11	181	9.2e-52	169.2	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2919290876	152	19.05	3	60	74	93	3.8e-06	2.7	COG2739	Predicted DNA-binding protein YlxM, UPF0122 family	105
2919290876	152	24.76	112	150	9	34	3.8e-06	16.4	COG2739	Predicted DNA-binding protein YlxM, UPF0122 family	105
2919290877	61	94.44	1	55	1	51	2.5e-18	60.2	COG5487	Uncharacterized membrane protein YtjA, UPF0391 family	54
2919290878	393	99.23	1	393	2	387	0.0e+00	624.3	COG0192	S-adenosylmethionine synthetase	388
2919290879	273	73.05	1	266	78	302	6.4e-57	187.1	COG1560	Lauroyl/myristoyl acyltransferase	308
2919290880	293	94.48	1	292	17	307	8.6e-76	249.2	COG1560	Lauroyl/myristoyl acyltransferase	308
2919290881	284	92.88	1	283	20	293	2.3e-35	116.9	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2919290882	251	97	23	224	4	197	2.9e-54	177.7	COG0218	GTP-binding protein EngB required for normal cell division	200
2919290883	209	53.33	133	209	43	114	6.8e-53	68.4	COG2863	Cytochrome c553	121
2919290883	209	93.33	1	132	9	134	6.8e-53	105.6	COG2863	Cytochrome c553	121
2919290884	717	99.62	27	686	1	519	5.3e-114	375.8	COG1333	Cytochrome c biogenesis protein ResB	478
2919290885	449	99.65	112	448	1	281	1.1e-71	235.9	COG0755	ABC-type transport system involved in cytochrome c biogenesis, permease component	281
2919290886	334	97.23	24	310	5	285	3.4e-91	299.4	COG2041	Periplasmic DMSO/TMAO reductase YedYZ, molybdopterin-dependent catalytic subunit	271
2919290887	218	88.21	2	213	15	201	3.3e-54	177.9	COG2717	Periplasmic DMSO/TMAO reductase YedYZ, heme-binding membrane subunit	209
2919290888	275	66.15	4	274	15	272	1.4e-64	212.4	COG0426	Flavorubredoxin	388
2919290889	109	99.06	1	108	1	105	1.2e-29	96.7	COG1965	Iron-binding protein CyaY, frataxin homolog	106
2919290890	743	92.08	1	740	31	762	0.0e+00	893	COG5009	Membrane carboxypeptidase/penicillin-binding protein	797
2919290891	353	98.87	1	352	4	353	6.1e-108	355.2	COG4972	Tfp pilus assembly protein, ATPase PilM	354
2919290892	206	91.83	1	205	7	197	5.2e-37	121.6	COG3166	Tfp pilus assembly protein PilN	206
2919290893	220	93.36	15	220	5	201	4.9e-63	206.7	COG3167	Tfp pilus assembly protein PilO	211
2919290894	180	96.47	4	179	6	169	9.0e-48	156.5	COG3168	Tfp pilus assembly protein PilP	170
2919290895	709	92.59	34	704	54	715	0.0e+00	509	COG4796	Type II secretory pathway, component HofQ	709
2919290897	363	99.17	1	363	2	358	0.0e+00	432.1	COG0337	3-dehydroquinate synthetase	360
2919290898	324	83.37	1	320	70	420	1.1e-85	282.7	COG0232	dGTP triphosphohydrolase	412
2919290899	220	91.33	7	196	7	185	6.2e-75	245	COG3310	Uncharacterized protein	196
2919290901	235	98.53	1	140	1	134	8.3e-21	68.6	COG1943	REP element-mobilizing transposase RayT	136
2919290902	1577	11.04	643	706	352	405	0.0e+00	3.4	COG0069	Glutamate synthase domain 2	485
2919290902	1577	96.38	1245	1565	2	294	1.0e-107	354	COG0070	Glutamate synthase domain 3	301
2919290902	1577	99.39	720	1239	2	487	0.0e+00	713.4	COG0069	Glutamate synthase domain 2	485
2919290902	1577	99.73	13	400	2	372	0.0e+00	478.7	COG0067	Glutamate synthase domain 1	371
2919290903	492	99.13	22	490	1	454	0.0e+00	561	COG0493	NADPH-dependent glutamate synthase beta chain or related oxidoreductase	457
2919290904	272	96.58	1	261	5	258	1.8e-103	339.5	COG1127	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, ATPase component MlaF	263
2919290905	260	93.63	5	260	15	264	1.5e-89	293.9	COG0767	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, permease component MlaE	267
2919290906	162	42.7	1	159	1	158	2.6e-47	155.9	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2919290907	264	92.43	18	261	7	238	2.5e-81	266.6	COG2853	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, lipoprotein component MlaA	250
2919290908	214	96.53	1	205	7	201	1.1e-52	172.9	COG2854	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic MlaC component	202
2919290909	90	84.85	1	89	13	96	1.1e-11	39.2	COG3113	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, MlaB component, contains STAS domain	99
2919290910	312	98.69	1	299	3	304	3.0e-87	287.1	COG1131	ABC-type multidrug transport system, ATPase component	293
2919290911	251	80.75	21	247	44	257	4.0e-20	65.8	COG1682	ABC-type polysaccharide/polyol phosphate export permease	263
2919290912	80	98.75	1	80	1	79	1.1e-31	103.2	COG5007	Acid stress-induced BolA-like protein IbaG/YrbA, predicted regulator of iron metabolism	80
2919290913	424	99.52	1	424	1	419	0.0e+00	591.7	COG0766	UDP-N-acetylglucosamine enolpyruvyl transferase	421
2919290914	219	75.09	4	219	1	220	2.9e-72	237.6	COG0040	ATP phosphoribosyltransferase	290
2919290915	460	97.2	8	456	10	426	0.0e+00	558.3	COG0141	Histidinol dehydrogenase	425
2919290917	484	98.46	6	477	4	452	1.4e-116	384	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
2919290918	74	24.04	4	62	29	53	9.5e-04	13.8	COG5467	Uncharacterized protein	104
2919290919	150	96.48	1	142	3	139	9.5e-17	55.2	COG5573	Predicted nucleic acid-binding protein, contains PIN domain	142
2919290920	373	97.78	11	373	3	355	4.6e-92	302.7	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
2919290921	212	99.49	16	212	2	195	6.7e-87	284.3	COG0131	Imidazoleglycerol phosphate dehydratase HisB	195
2919290922	223	99.02	3	223	2	203	2.2e-70	230.7	COG0118	Imidazoleglycerol phosphate synthase glutamine amidotransferase subunit HisH	204
2919290923	246	97.93	1	243	2	237	2.2e-92	302.7	COG0106	Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase	241
2919290924	266	99.61	1	266	1	256	2.5e-115	378.3	COG0107	Imidazole glycerol phosphate synthase subunit HisF	256
2919290925	129	91.96	1	110	7	109	2.7e-43	140.7	COG0139	Phosphoribosyl-AMP cyclohydrolase	111
2919290926	124	97.92	7	113	1	94	6.6e-32	102.5	COG0140	Phosphoribosyl-ATP pyrophosphohydrolase	92
2919290927	128	83.2	2	128	14	117	9.6e-15	48.5	COG3671	Uncharacterized membrane protein	125
2919290928	345	68.97	2	287	9	228	5.9e-39	127.2	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
2919290929	118	73.05	4	115	2	104	1.6e-29	96.7	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
2919290930	80	76.6	1	80	1	72	4.3e-21	69.4	COG1826	Sec-independent protein translocase protein TatA	94
2919290931	154	93.62	1	105	1	88	1.6e-19	64.1	COG1826	Sec-independent protein translocase protein TatA	94
2919290932	264	94.59	7	262	6	250	9.2e-79	258.6	COG0805	Sec-independent protein secretion pathway component TatC	255
2919290933	382	98.36	6	379	4	362	1.1e-117	387.2	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
2919290934	257	98.43	3	257	4	253	3.1e-66	217.4	COG0327	Putative GTP cyclohydrolase 1 type 2, NIF3 family	250
2919290935	342	97.28	1	342	4	325	2.2e-104	343.7	COG1995	4-hydroxy-L-threonine phosphate dehydrogenase PdxA	332
2919290936	142	99.24	1	142	1	130	7.1e-50	163	COG1970	Large-conductance mechanosensitive channel	130
2919290937	199	91.11	1	199	9	172	1.3e-46	152.9	COG0723	Rieske Fe-S protein	177
2919290938	471	99.26	12	465	4	405	0.0e+00	548.4	COG1290	Cytochrome b subunit of the bc complex	381
2919290939	253	88.09	2	253	34	277	1.9e-54	179.3	COG2857	Cytochrome c1	250
2919290940	203	94.88	1	202	1	204	1.4e-45	149.9	COG0625	Glutathione S-transferase	211
2919290941	178	70.32	2	178	3	111	3.9e-52	169.7	COG2969	Stringent starvation protein B	155
2919290944	310	43.67	48	293	177	314	3.7e-55	182.3	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
2919290945	918	99.76	2	911	3	840	0.0e+00	1277.7	COG0653	Preprotein translocase subunit SecA (ATPase, RNA helicase)	822
2919290946	409	98.27	3	409	8	405	0.0e+00	491.5	COG1364	N-acetylglutamate synthase (N-acetylornithine aminotransferase)	404
2919290947	290	96.54	1	290	5	283	1.6e-113	372.8	COG2607	Predicted ATPase, AAA+ superfamily	287
2919290948	152	54.07	8	147	8	100	5.5e-20	66.3	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2919290949	72	83.08	8	72	5	58	1.6e-22	70.9	COG3024	Endogenous inhibitor of DNA gyrase, YacG/DUF329 family	65
2919290950	251	99.18	1	251	2	243	7.1e-74	242.6	COG4582	Cell division protein ZapD, interacts with FtsZ	244
2919290951	206	91.54	6	204	3	186	1.1e-55	182.7	COG0237	Dephospho-CoA kinase	201
2919290952	290	94.53	9	286	7	248	2.4e-69	228	COG1989	Prepilin signal peptidase PulO (type II secretory pathway) or related peptidase	254
2919290953	406	99.25	13	406	3	397	0.0e+00	474.2	COG1459	Type II secretory pathway, component PulF	397
2919290954	579	98.43	72	579	8	507	0.0e+00	596.7	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
2919290956	327	99.09	9	327	3	327	3.8e-100	329.3	COG0142	Geranylgeranyl pyrophosphate synthase	322
2919290957	103	99.03	1	103	1	102	2.5e-42	137.8	COG0261	Ribosomal protein L21	103
2919290958	85	95.4	1	85	1	83	3.1e-41	133.5	COG0211	Ribosomal protein L27	87
2919290959	356	92.84	1	352	1	337	0.0e+00	470.6	COG0536	GTPase involved in cell partioning and DNA repair	369
2919290960	380	98.92	4	377	4	369	0.0e+00	430.8	COG0263	Glutamate 5-kinase	369
2919290962	225	90.12	1	160	11	165	1.1e-23	78.1	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2919290963	580	99.43	1	575	1	524	0.0e+00	675.5	COG0442	Prolyl-tRNA synthetase	500
2919290964	228	70.96	18	224	54	268	5.1e-28	92.7	COG0741	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)	296
2919290965	447	98.63	1	432	2	433	3.2e-128	422.2	COG1253	Hemolysin or related protein, contains CBS domains	429
2919290966	335	22.58	27	267	331	507	1.2e-35	117	COG0466	ATP-dependent Lon protease, bacterial type	782
2919290967	107	96.19	1	107	2	102	1.3e-45	147.8	COG0278	Glutaredoxin-related protein	105
2919290968	286	95.47	3	282	10	283	4.0e-76	249.9	COG2890	Methylase of polypeptide chain release factors	280
2919290969	362	99.17	1	358	2	361	0.0e+00	520.3	COG0216	Protein chain release factor A	363
2919290970	439	99.03	1	431	1	410	9.7e-130	427.2	COG0373	Glutamyl-tRNA reductase	414
2919290971	92	52.67	11	91	61	129	3.8e-04	14.3	COG3788	Uncharacterized membrane protein YecN, MAPEG domain	131
2919290972	322	98.75	1	321	3	317	4.5e-93	306	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2919290973	253	95.2	2	252	6	263	1.3e-49	163.2	COG0584	Glycerophosphoryl diester phosphodiesterase	257
2919290974	134	76.71	27	134	12	123	1.7e-05	20.1	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2919290975	336	99.71	1	329	1	349	0.0e+00	457.7	COG3839	ABC-type sugar transport system, ATPase component	338
2919290976	283	95.41	1	283	10	279	4.5e-83	273.1	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
2919290977	293	97.32	2	293	4	293	5.2e-85	279.6	COG1175	ABC-type sugar transport system, permease component	295
2919290978	437	98.65	1	432	5	441	6.0e-65	214.5	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
2919290979	409	98.77	8	336	3	324	6.1e-110	361.2	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
2919290980	1304	98.5	825	1284	5	399	3.0e-65	208.8	COG0247	Fe-S oxidoreductase	388
2919290980	1304	99.36	152	778	2	467	0.0e+00	539.5	COG0277	FAD/FMN-containing dehydrogenase	459
2919290981	143	92.91	1	133	4	134	5.5e-26	85.3	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
2919290982	140	96.67	8	126	4	119	2.9e-53	173	COG3536	Uncharacterized conserved protein, DUF971 family	120
2919290983	243	99.58	8	243	1	238	6.2e-88	288.1	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
2919290984	345	99.64	33	345	1	280	6.5e-30	93.8	COG4395	Predicted lipid-binding transport protein, Tim44 family	281
2919290985	212	71.08	24	192	6	150	1.8e-20	67.4	COG3165	Ubiquinone biosynthesis protein UbiJ, contains SCP2 domain	204
2919290986	521	87.3	16	518	50	496	0.0e+00	560.7	COG0661	Predicted unusual protein kinase regulating ubiquinone biosynthesis, AarF/ABC1/UbiB family	517
2919290987	481	94.2	1	475	5	475	8.8e-85	279.3	COG0591	Na+/proline symporter	493
2919290988	113	91.46	1	75	8	82	3.3e-31	101.6	COG2331	Predicted nucleic acid-binding protein, contains Zn-ribbon domain	82
2919290989	206	89.19	1	204	4	201	2.5e-78	256.6	COG2928	Uncharacterized membrane protein	222
2919290990	605	99.83	3	598	1	585	0.0e+00	851.8	COG0173	Aspartyl-tRNA synthetase	585
2919290991	276	57.25	5	271	86	231	6.4e-05	16.1	COG1462	Curli biogenesis system outer membrane secretion channel CsgG	252
2919290992	157	74.42	6	149	18	145	1.9e-16	54.6	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2919290993	588	85.71	9	520	6	119	2.0e-12	41.1	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2919290994	245	96.89	2	245	6	254	8.5e-53	173.6	COG3568	Metal-dependent hydrolase, endonuclease/exonuclease/phosphatase family	259
2919290995	414	85.57	2	407	66	480	3.5e-68	224.5	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
2919290996	241	90.36	44	240	17	194	4.4e-47	154	COG0302	GTP cyclohydrolase I	195
2919290998	293	95.35	2	293	8	294	6.0e-14	44	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2919291001	223	96.17	1	212	2	202	2.1e-50	165.5	COG0406	Broad specificity phosphatase PhoE	208
2919291005	470	99.79	1	466	1	480	2.9e-116	383.4	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
2919291006	496	95.33	1	494	11	561	3.3e-100	330.6	COG0747	ABC-type transport system, periplasmic component	556
2919291007	293	48.01	2	276	285	549	1.8e-101	334.6	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
2919291008	345	99.38	3	327	1	323	6.9e-124	407.2	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
2919291009	292	94.97	4	291	15	297	1.8e-94	310.1	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
2919291010	320	99.37	1	319	1	316	3.0e-108	356.2	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
2919291011	85	59.68	1	77	40	113	1.7e-15	51.1	COG1145	Ferredoxin	99
2919291012	202	98.94	1	190	1	187	1.8e-70	230.5	COG0193	Peptidyl-tRNA hydrolase	190
2919291013	211	96.77	1	93	4	93	1.0e-30	99.2	COG1825	Ribosomal protein L25 (general stress protein Ctc)	93
2919291014	324	98.43	3	318	5	317	0.0e+00	436.8	COG0462	Phosphoribosylpyrophosphate synthetase	314
2919291016	285	88.62	2	277	4	260	3.2e-79	260.2	COG1947	4-diphosphocytidyl-2C-methyl-D-erythritol kinase	289
2919291017	138	48.54	6	124	51	150	4.9e-14	46.5	COG3017	Outer membrane lipoprotein LolB, involved in outer membrane biogenesis	206
2919291018	587	66.3	43	326	98	341	6.7e-19	17.1	COG0457	Tetratricopeptide (TPR) repeat	291
2919291018	587	97.01	258	583	3	359	6.7e-19	54.8	COG0457	Tetratricopeptide (TPR) repeat	291
2919291019	271	100	1	270	1	274	4.9e-83	273.2	COG0266	Formamidopyrimidine-DNA glycosylase	273
2919291021	356	98.02	1	353	6	352	4.8e-117	385.6	COG1194	Adenine-specific DNA glycosylase, acts on AG and A-oxoG pairs	342
2919291022	287	98.95	3	287	2	284	1.2e-107	353.8	COG1660	RNase adaptor protein for sRNA GlmZ degradation, contains a P-loop ATPase domain	286
2919291023	572	99.28	2	549	2	555	0.0e+00	605.8	COG0497	DNA repair ATPase RecN	557
2919291024	298	94.39	8	295	17	285	2.7e-76	250.5	COG0061	NAD kinase	281
2919291025	334	98.84	1	334	3	343	5.2e-106	349.2	COG1420	Transcriptional regulator of heat shock response	346
2919291026	72	77.14	11	72	5	58	9.1e-13	42.2	COG3311	Predicted DNA-binding transcriptional regulator AlpA	70
2919291029	393	60.61	78	330	11	170	8.4e-13	42.7	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
2919291031	118	76.71	1	77	15	70	1.5e-12	41	COG3655	DNA-binding transcriptional regulator, XRE family	73
2919291035	60	9.09	14	58	173	208	4.6e-07	23.1	COG3328	Transposase (or an inactivated derivative)	379
2919291036	689	76.8	210	684	27	400	1.4e-62	205.8	COG1061	Superfamily II DNA or RNA helicase	442
2919291038	676	10.22	1	130	1	97	3.3e-19	47.7	COG0419	DNA repair exonuclease SbcCD ATPase subunit	908
2919291038	676	33.61	171	613	586	904	3.3e-19	12.4	COG0419	DNA repair exonuclease SbcCD ATPase subunit	908
2919291042	153	56.99	7	153	74	179	5.6e-09	29.5	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2919291045	660	8.32	5	125	6	84	6.4e-19	30.7	COG0419	DNA repair exonuclease SbcCD ATPase subunit	908
2919291045	660	13.7	185	346	647	776	6.4e-19	11.5	COG0419	DNA repair exonuclease SbcCD ATPase subunit	908
2919291045	660	22.76	349	636	693	908	6.4e-19	24.4	COG0419	DNA repair exonuclease SbcCD ATPase subunit	908
2919291046	528	81.72	3	431	30	248	4.5e-52	170.8	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
2919291049	451	66.87	140	387	40	263	3.9e-10	33.8	COG0582	Integrase	309
2919291052	188	99.34	31	182	1	151	2.7e-47	154.6	COG0782	Transcription elongation factor, GreA/GreB family	151
2919291053	759	98.34	30	755	12	723	0.0e+00	823.6	COG0317	(p)ppGpp synthase/hydrolase, HD superfamily	701
2919291054	67	91.89	1	67	1	68	1.5e-21	70.4	COG1758	DNA-directed RNA polymerase, subunit K/omega	74
2919291055	206	95.38	1	197	6	191	1.3e-76	250.6	COG0194	Guanylate kinase	191
2919291056	300	98.97	2	300	4	290	2.9e-79	260.7	COG1561	Uncharacterized conserved protein YicC, UPF0701 family	290
2919291057	338	65.74	13	327	2	310	4.6e-44	145.3	COG0515	Serine/threonine protein kinase	384
2919291058	300	93.01	1	248	7	259	1.1e-47	155	COG0631	Serine/threonine protein phosphatase PrpC	262
2919291059	244	96.54	2	241	9	231	2.0e-95	312.5	COG0689	Ribonuclease PH	230
2919291060	199	98.46	1	197	2	193	1.1e-57	188.7	COG0127	Inosine/xanthosine triphosphate pyrophosphatase, all-alpha NTP-PPase family	194
2919291061	416	90.48	15	416	36	415	7.3e-124	407.6	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
2919291063	583	17.77	123	210	123	165	1.0e-16	11.2	COG2202	PAS domain	232
2919291063	583	59.5	217	413	99	242	1.0e-16	39.3	COG2202	PAS domain	232
2919291063	583	96.72	401	581	6	182	7.5e-55	179	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2919291067	226	96.97	9	217	5	196	1.1e-69	227.8	COG0378	Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase	202
2919291068	236	97.82	10	236	6	229	2.1e-59	195.5	COG0830	Urease accessory protein UreF	229
2919291069	223	86.54	1	189	20	154	1.6e-34	109.1	COG2371	Urease accessory protein UreE	155
2919291070	165	70.37	10	153	43	156	3.8e-12	40.9	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2919291071	572	100	1	572	1	569	0.0e+00	1025.4	COG0804	Urease alpha subunit	568
2919291073	101	95.28	1	101	1	101	4.9e-47	152.6	COG0832	Urease beta subunit	106
2919291074	204	96.52	1	204	5	198	1.8e-49	162	COG2370	Hydrogenase/urease accessory protein HupE	201
2919291075	100	99	1	100	1	99	2.5e-54	175.8	COG0831	Urease gamma subunit	100
2919291076	1204	83.76	587	968	61	390	1.9e-74	244.1	COG0642	Signal transduction histidine kinase	336
2919291076	1204	93.53	43	510	14	432	2.1e-20	66.3	COG1457	Purine-cytosine permease or related protein	442
2919291076	1204	93.98	990	1122	4	128	3.7e-26	83.8	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2919291077	356	53.02	25	188	3	125	4.4e-41	134.2	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2919291077	356	78.75	275	348	14	76	1.6e-22	70.1	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2919291080	911	95.03	18	910	39	956	0.0e+00	701	COG0474	Magnesium-transporting ATPase (P-type)	917
2919291081	108	98.99	1	108	1	98	3.5e-05	17.3	COG3668	Plasmid stabilization system protein ParE	98
2919291082	228	62.75	13	144	9	104	8.1e-05	16.3	COG1406	Chemotaxis protein CheX, a CheY~P-specific phosphatase	153
2919291083	393	82.35	3	370	7	300	4.1e-26	86	COG3535	Uncharacterized conserved protein, DUF917 family	357
2919291084	351	95.08	138	327	7	180	2.5e-49	160.9	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2919291085	153	96.79	1	152	2	152	2.6e-60	196.7	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
2919291086	756	97.85	1	756	7	735	0.0e+00	473	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
2919291087	397	97.22	1	383	10	393	9.4e-129	423.5	COG2814	Predicted arabinose efflux permease, MFS family	394
2919291088	420	98.36	12	396	5	364	4.6e-73	240.4	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2919291089	526	97.67	228	525	7	300	9.6e-98	321.2	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2919291090	379	97.83	24	370	6	321	2.2e-91	300.5	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2919291091	291	96.48	40	291	7	253	3.0e-120	394.4	COG4674	ABC-type uncharacterized transport system, ATPase component	249
2919291092	230	94.94	1	228	3	227	1.3e-87	286.9	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2919291093	286	68.97	78	278	51	210	2.5e-26	87.6	COG0671	Membrane-associated phospholipid phosphatase	232
2919291094	362	87.75	27	329	34	298	5.1e-40	131	COG1597	Diacylglycerol kinase family enzyme	301
2919291095	262	79.75	2	251	3	317	6.1e-12	38.3	COG1409	3',5'-cyclic AMP phosphodiesterase CpdA	301
2919291096	360	85.25	8	248	27	234	2.2e-50	165.1	COG2114	Adenylate cyclase, class 3	227
2919291097	248	88.74	18	248	4	208	1.0e-23	78.6	COG1011	FMN phosphatase YigB, HAD superfamily	229
2919291098	408	98.23	11	397	5	393	3.2e-125	412.2	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
2919291100	278	98.16	1	276	6	272	3.7e-50	165	COG0829	Urease accessory protein UreH	269
2919291101	465	92.32	11	444	34	466	2.1e-38	125	COG0277	FAD/FMN-containing dehydrogenase	459
2919291102	306	96.51	44	303	8	256	7.3e-62	203.1	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2919291103	280	96.81	21	276	4	246	4.8e-89	292.2	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2919291104	334	91.34	1	331	12	317	7.1e-37	121.5	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2919291105	287	97.19	12	264	4	245	7.2e-71	232.5	COG1402	 Creatinine amidohydrolase/Fe(II)-dependent formamide hydrolase involved in riboflavin and F420 biosynthesis	250
2919291106	162	89.71	4	157	14	135	2.0e-20	65.8	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
2919291107	446	83.96	19	423	24	379	1.5e-35	116.4	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
2919291108	195	98.43	1	195	1	188	4.5e-43	141.4	COG2249	Putative NADPH-quinone reductase (modulator of drug activity B)	189
2919291109	100	73.79	6	100	13	88	1.7e-09	31.5	COG0633	Ferredoxin	102
2919291110	224	79.9	7	218	17	183	2.4e-19	64.8	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2919291111	207	95.42	48	207	6	151	2.1e-31	103	COG0590	tRNA(Arg) A34 adenosine deaminase TadA	152
2919291112	331	87.38	25	328	3	286	9.3e-56	178.7	COG3491	Isopenicillin N synthase and related dioxygenases	322
2919291113	138	18.9	2	53	11	34	7.0e-12	12.6	COG3324	Predicted enzyme related to lactoylglutathione lyase	127
2919291113	138	42.52	60	132	70	123	7.0e-12	25.9	COG3324	Predicted enzyme related to lactoylglutathione lyase	127
2919291114	335	94.15	1	327	6	311	1.2e-88	291.7	COG3491	Isopenicillin N synthase and related dioxygenases	322
2919291115	342	98.21	1	342	4	332	1.4e-34	113.8	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2919291116	265	98.85	1	265	1	257	2.4e-117	385.3	COG3622	Hydroxypyruvate isomerase	260
2919291117	355	91.4	25	352	21	360	2.0e-54	175.9	COG2021	Homoserine acetyltransferase	368
2919291118	236	87.95	6	235	4	200	8.2e-38	124.3	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
2919291119	425	99.04	6	424	3	413	0.0e+00	446.2	COG3395	Uncharacterized conserved protein YgbK, DUF1537 family	413
2919291120	303	99.3	4	292	2	285	1.6e-87	287.4	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
2919291121	455	99.11	3	454	3	447	3.1e-119	392.5	COG2610	H+/gluconate symporter or related permease	442
2919291122	259	95.02	6	237	6	234	5.1e-62	203.3	COG2186	DNA-binding transcriptional regulator, FadR family	241
2919291123	347	94.67	37	324	9	310	5.9e-66	216.4	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
2919291124	73	39.87	1	73	91	151	3.7e-08	27.7	COG0590	tRNA(Arg) A34 adenosine deaminase TadA	152
2919291125	84	52.29	6	84	6	85	9.2e-11	36.1	COG0590	tRNA(Arg) A34 adenosine deaminase TadA	152
2919291126	255	96.12	1	252	8	255	3.4e-71	233.8	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2919291127	274	96.02	6	268	4	244	2.0e-85	280.4	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2919291128	343	97.91	1	339	4	331	8.5e-33	108	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2919291129	768	97.06	1	439	12	440	0.0e+00	568.1	COG0281	Malic enzyme	432
2919291129	768	99.08	436	767	2	325	4.8e-109	358.3	COG0280	Phosphotransacetylase	327
2919291130	495	96.93	1	493	7	448	0.0e+00	518.5	COG2233	Xanthine/uracil permease	451
2919291131	234	87.07	1	205	18	219	6.1e-50	164	COG1802	DNA-binding transcriptional regulator, GntR family	230
2919291132	426	98.09	1	425	3	412	0.0e+00	456.3	COG1301	Na+/H+-dicarboxylate symporter	415
2919291133	595	97.98	34	595	12	545	0.0e+00	697.8	COG0405	Gamma-glutamyltranspeptidase	539
2919291134	411	97.37	10	411	10	416	6.0e-72	237	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
2919291135	592	16.99	186	326	33	103	2.8e-41	31.5	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
2919291135	592	62.44	343	589	157	417	2.8e-41	102.8	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
2919291135	592	93.18	1	177	7	170	3.3e-59	193.4	COG3195	2-oxo-4-hydroxy-4-carboxy--5-ureidoimidazoline (OHCU) decarboxylase	176
2919291136	326	95.52	8	319	11	266	1.4e-44	146.4	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
2919291137	222	90.09	1	216	16	224	2.7e-60	197.8	COG1802	DNA-binding transcriptional regulator, GntR family	230
2919291138	116	91.94	1	116	11	124	9.5e-47	152.3	COG2351	5-hydroxyisourate hydrolase (purine catabolism), transthyretin-related family	124
2919291140	275	90.37	2	275	14	285	4.8e-57	187.1	COG1975	Xanthine and CO dehydrogenase maturation factor, XdhC/CoxF family	278
2919291141	414	99.26	1	413	1	405	0.0e+00	473.2	COG3748	Uncharacterized membrane protein	407
2919291142	110	97.17	5	110	2	104	9.6e-32	103.8	COG2076	Multidrug transporter EmrE and related cation transporters	106
2919291143	625	89.07	405	605	13	175	2.3e-22	72.9	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2919291143	625	90.27	10	280	12	243	1.3e-55	181.8	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
2919291144	451	98.82	14	451	5	421	0.0e+00	547.6	COG2379	Glycerate-2-kinase	422
2919291145	346	98.06	1	346	8	360	1.5e-49	163.1	COG3203	Outer membrane protein (porin)	354
2919291146	207	82.11	6	199	34	212	6.7e-13	42.6	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2919291147	708	51.24	103	507	118	241	1.7e-12	39.9	COG2202	PAS domain	232
2919291147	708	95.08	495	690	8	181	4.5e-44	143.7	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2919291149	782	97.7	2	782	12	774	0.0e+00	1105.2	COG4631	Xanthine dehydrogenase, molybdopterin-binding subunit B	781
2919291150	503	96.55	1	502	8	483	0.0e+00	564.6	COG4630	Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A	493
2919291151	290	95.02	1	290	13	298	1.2e-48	160.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919291152	528	99.4	13	506	4	501	0.0e+00	590.4	COG3845	ABC-type uncharacterized transport system, ATPase component	501
2919291153	357	96.37	3	355	6	350	2.4e-106	349.2	COG4603	ABC-type uncharacterized transport system, permease component	356
2919291154	306	97.04	1	306	7	301	2.2e-98	323	COG1079	ABC-type uncharacterized transport system, permease component	304
2919291155	388	98.58	5	365	2	349	2.0e-92	303.9	COG1744	Basic membrane lipoprotein Med, periplasmic binding protein (PBP1-ABC) superfamily	345
2919291156	327	90.43	2	326	28	367	2.1e-62	205.4	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
2919291157	350	96.24	13	348	7	339	3.9e-107	352.2	COG1816	Adenosine deaminase	345
2919291158	524	92.94	39	514	31	425	2.7e-110	363.6	COG0840	Methyl-accepting chemotaxis protein	408
2919291159	366	91.78	1	342	15	338	1.4e-79	261.6	COG1744	Basic membrane lipoprotein Med, periplasmic binding protein (PBP1-ABC) superfamily	345
2919291160	432	90.33	1	428	21	403	2.4e-100	330.1	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
2919291161	190	97.84	2	190	2	182	3.4e-66	216.6	COG0717	Deoxycytidine triphosphate deaminase	183
2919291163	567	95.24	306	387	5	84	5.0e-11	37.2	COG2770	HAMP domain	83
2919291163	567	96.72	388	566	6	182	2.1e-53	174.4	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2919291164	329	94.24	10	322	7	317	3.1e-58	191.5	COG2423	Ornithine cyclodeaminase/archaeal alanine dehydrogenase, mu-crystallin family	330
2919291165	224	97.1	14	217	2	202	2.2e-73	240.6	COG2039	Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase)	207
2919291166	294	98.99	1	294	1	293	2.8e-118	388.6	COG2321	Predicted metalloprotease	295
2919291167	729	88.45	33	588	27	524	5.9e-45	147.4	COG0659	Sulfate permease or related transporter, MFS superfamily	554
2919291168	140	92.48	10	139	4	126	3.0e-36	118.5	COG2346	Truncated hemoglobin YjbI	133
2919291169	197	97.84	2	195	4	184	3.5e-57	186.8	COG1704	Uncharacterized conserved protein	185
2919291170	363	90.06	7	325	23	303	2.8e-32	105.3	COG0501	Zn-dependent protease with chaperone function	302
2919291171	159	87.5	6	159	16	134	2.4e-17	57.2	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
2919291173	688	96.78	18	609	4	514	1.5e-130	430.1	COG0737	2',3'-cyclic-nucleotide 2'-phosphodiesterase/5'- or 3'-nucleotidase, 5'-nucleotidase family	517
2919291174	311	92.93	112	306	9	179	1.2e-44	147	COG2840	DNA-nicking endonuclease, Smr domain	184
2919291175	237	99.11	1	237	2	223	5.7e-78	255	COG2003	DNA repair protein RadC, contains a helix-hairpin-helix DNA-binding motif	224
2919291176	154	77.97	9	154	3	140	1.2e-32	106.9	COG1047	FKBP-type peptidyl-prolyl cis-trans isomerase 2	174
2919291177	331	98.31	4	296	2	291	5.1e-124	407.1	COG0761	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH	294
2919291178	242	100	91	223	1	163	2.6e-20	66.5	COG0517	CBS domain	117
2919291179	313	89.6	1	313	12	321	7.3e-81	266.1	COG1171	Threonine dehydratase	347
2919291180	438	99.3	1	438	1	428	0.0e+00	591.4	COG0172	Seryl-tRNA synthetase	429
2919291182	345	98.55	1	345	4	344	0.0e+00	474.2	COG0709	Selenophosphate synthase	346
2919291183	368	98.81	1	342	4	334	1.3e-113	373.6	COG2603	tRNA 2-selenouridine synthase SelU, contains rhodanese domain	334
2919291184	778	80.2	442	774	76	391	1.4e-50	167.3	COG0642	Signal transduction histidine kinase	336
2919291184	778	96.31	2	394	11	401	9.8e-59	192.4	COG4252	Extracellular (periplasmic) sensor domain CHASE2 (specificity unknown)	400
2919291185	580	79.35	37	413	3	271	9.6e-40	130.3	COG4254	Uncharacterized conserved protein, contains LysM and FecR  domains	339
2919291186	232	99.14	1	227	1	230	3.5e-63	207.1	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2919291187	352	83.48	8	346	55	332	6.0e-70	230.2	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
2919291189	667	36.7	198	366	251	399	1.9e-33	45.2	COG4252	Extracellular (periplasmic) sensor domain CHASE2 (specificity unknown)	400
2919291189	667	40.15	1	186	7	169	1.9e-33	71.2	COG4252	Extracellular (periplasmic) sensor domain CHASE2 (specificity unknown)	400
2919291189	667	88.11	346	598	21	235	6.2e-53	174	COG2114	Adenylate cyclase, class 3	227
2919291190	1138	87.23	222	592	26	346	5.9e-11	36	COG0457	Tetratricopeptide (TPR) repeat	291
2919291191	433	81.36	350	405	5	52	1.5e-08	27.4	COG3422	Uncharacterized conserved protein YegP, UPF0339 family	59
2919291191	433	98.42	1	313	5	316	7.3e-85	279	COG0180	Tryptophanyl-tRNA synthetase	314
2919291192	222	86.02	3	220	14	216	1.4e-35	117	COG1994	Zn-dependent protease (includes SpoIVFB)	230
2919291193	382	81.88	13	382	78	425	5.0e-99	326.5	COG0840	Methyl-accepting chemotaxis protein	408
2919291194	211	95.75	2	211	2	204	2.1e-58	191	COG0009	tRNA A37 threonylcarbamoyladenosine synthetase subunit TsaC/SUA5/YrdC	211
2919291196	285	97.67	4	266	2	253	1.5e-72	238.5	COG0613	Predicted metal-dependent phosphoesterase TrpH, contains PHP domain	258
2919291197	590	13.65	36	149	336	393	8.1e-112	4	COG0840	Methyl-accepting chemotaxis protein	408
2919291197	590	90.35	124	513	42	425	8.1e-112	368.8	COG0840	Methyl-accepting chemotaxis protein	408
2919291198	74	92.75	1	70	1	64	4.2e-23	75	COG1942	Phenylpyruvate tautomerase PptA, 4-oxalocrotonate tautomerase family	69
2919291199	574	93.45	37	556	20	490	0.0e+00	469	COG0608	Single-stranded DNA-specific exonuclease, DHH superfamily, may be involved in archaeal DNA replication intiation	491
2919291200	320	64.78	20	291	4	209	2.7e-32	104.7	COG4255	Uncharacterized protein	318
2919291201	417	99.51	1	417	3	410	0.0e+00	456.4	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
2919291202	228	96.93	4	228	4	224	1.5e-83	273.8	COG4181	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component	228
2919291204	352	60.43	7	324	165	416	5.9e-39	127.6	COG1721	Uncharacterized conserved protein, DUF58 family, contains vWF domain	416
2919291205	338	98.48	4	328	5	329	1.5e-94	310.9	COG0714	MoxR-like ATPase	329
2919291206	315	67.12	28	312	9	253	7.5e-54	177.1	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
2919291207	282	98.05	2	268	3	254	1.7e-62	205.2	COG0084	Tat protein secretion system quality control protein TatD (DNase activity)	256
2919291208	209	94.67	27	206	1	160	5.6e-30	97.1	COG3663	G:T/U-mismatch repair DNA glycosylase	169
2919291209	254	88.3	2	253	19	267	9.9e-32	104.1	COG0421	Spermidine synthase	282
2919291210	597	96.46	97	595	17	506	0.0e+00	544.2	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
2919291212	503	99.01	1	503	1	499	0.0e+00	679.4	COG3333	TctA family transporter	504
2919291213	432	96.46	2	432	9	417	1.2e-103	341.3	COG4949	Uncharacterized membrane-anchored protein	424
2919291214	299	96.68	5	299	6	296	5.5e-36	118.4	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2919291215	346	47.42	47	343	31	260	1.6e-48	159.8	COG4783	Putative Zn-dependent protease, contains TPR repeats	484
2919291217	276	98.13	4	272	4	266	7.6e-43	140.9	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2919291218	371	76.81	11	307	20	274	5.0e-24	79	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
2919291219	891	70.59	279	889	177	644	1.3e-112	370.5	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2919291220	299	96.01	1	299	8	296	1.0e-41	137.4	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2919291221	327	99.09	2	327	3	330	1.5e-97	321	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2919291222	277	55.23	104	270	19	113	2.9e-11	37.3	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2919291223	364	97.51	11	334	3	315	2.1e-35	116.6	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2919291224	310	95.68	10	300	7	294	1.8e-57	189.3	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919291225	307	98.01	3	297	1	295	4.5e-67	220.9	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919291226	327	95.06	1	327	5	312	7.2e-98	321.8	COG0385	Predicted Na+-dependent transporter	319
2919291227	551	99.07	1	536	5	534	0.0e+00	557.1	COG1283	Na+/phosphate symporter	533
2919291228	167	91.02	8	167	10	161	9.2e-48	155.8	COG0597	Lipoprotein signal peptidase	167
2919291229	957	99.47	13	950	2	943	0.0e+00	1046.9	COG0060	Isoleucyl-tRNA synthetase	933
2919291230	349	100	1	330	1	307	6.0e-89	291.7	COG0196	FAD synthase	304
2919291232	436	20.21	83	164	11	68	3.1e-58	9.5	COG4976	Predicted methyltransferase, contains TPR repeat	287
2919291232	436	21.6	15	93	2	63	3.1e-58	10.7	COG4976	Predicted methyltransferase, contains TPR repeat	287
2919291232	436	95.82	151	436	12	286	3.1e-58	169.1	COG4976	Predicted methyltransferase, contains TPR repeat	287
2919291233	630	81.73	285	628	67	388	3.9e-56	185.5	COG0642	Signal transduction histidine kinase	336
2919291234	227	97.84	5	227	2	228	2.0e-46	152.3	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2919291237	464	31.53	11	253	21	113	5.3e-08	26.7	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2919291238	371	98.75	1	368	1	394	5.3e-54	177.9	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2919291239	393	98.75	1	393	1	394	3.9e-81	267.2	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2919291240	233	97.67	6	218	5	214	6.0e-66	216.5	COG3132	Uncharacterized conserved protein YceH, UPF0502 family	215
2919291241	193	92.5	2	193	2	186	6.4e-74	242	COG0299	Folate-dependent phosphoribosylglycinamide formyltransferase PurN	200
2919291242	84	56.45	3	84	38	107	3.4e-23	76.4	COG4728	Uncharacterized protein	124
2919291244	424	87.71	75	424	44	357	8.2e-97	318.8	COG0144	16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family	355
2919291245	404	85.86	6	270	40	288	4.1e-85	279.5	COG1398	Fatty-acid desaturase	289
2919291246	56	94.12	4	54	4	51	1.7e-24	80.1	COG0267	Ribosomal protein L33	50
2919291247	77	98.7	1	76	1	76	7.8e-37	119.5	COG0227	Ribosomal protein L28	77
2919291248	317	99.02	4	317	2	305	2.2e-124	408.6	COG0492	Thioredoxin reductase	305
2919291249	225	95.41	10	220	2	209	6.1e-39	127.9	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2919291250	778	14.7	38	212	48	184	0.0e+00	.9	COG1674	DNA segregation ATPase FtsK/SpoIIIE and related proteins	858
2919291250	778	53.65	213	778	429	928	0.0e+00	793.4	COG1674	DNA segregation ATPase FtsK/SpoIIIE and related proteins	858
2919291251	210	95.31	1	210	10	212	7.6e-38	124.3	COG2834	Outer membrane lipoprotein-sorting protein	211
2919291252	451	97.03	6	440	9	432	0.0e+00	580.1	COG2256	Replication-associated recombination protein RarA (DNA-dependent ATPase)	436
2919291253	309	98.34	1	308	2	297	7.1e-87	285.8	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2919291254	358	97.21	1	353	6	319	3.4e-95	313	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2919291255	260	99.21	5	257	3	254	1.5e-104	342.8	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2919291256	242	98.73	7	242	3	236	1.2e-94	310	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2919291257	120	96.55	3	119	5	116	1.5e-58	190.2	COG3169	Uncharacterized conserved protein, DUF486 family	116
2919291258	215	98.62	1	214	4	217	2.0e-49	162.1	COG1392	Uncharacterized conserved protein YkaA, distantly related to PhoU, UPF0111/DUF47 family	217
2919291259	336	99.44	7	336	3	354	2.5e-96	316.6	COG0306	Phosphate/sulfate permease	326
2919291261	173	96.45	1	169	3	165	1.4e-54	178.7	COG1247	L-amino acid N-acyltransferase YncA	169
2919291262	83	88.89	1	83	1	80	4.9e-32	103.9	COG0228	Ribosomal protein S16	87
2919291263	190	95.4	9	190	6	171	5.8e-50	163.2	COG0806	Ribosomal 30S subunit maturation factor RimM, required for 16S rRNA processing	174
2919291264	252	93.85	1	249	1	229	5.6e-92	301.1	COG0336	tRNA G37 N-methylase TrmD	240
2919291265	127	94.26	1	116	7	121	2.2e-50	163.8	COG0335	Ribosomal protein L19	115
2919291266	239	86.63	63	216	12	160	2.2e-20	67.1	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2919291267	328	96.56	1	328	10	318	1.5e-46	152.7	COG1270	Cobalamin biosynthesis protein CobD/CbiB	320
2919291268	314	93.38	4	314	15	296	3.7e-72	237	COG1162	Putative ribosome biogenesis GTPase RsgA	301
2919291269	112	93.07	13	112	3	96	1.6e-30	99.2	COG2154	Pterin-4a-carbinolamine dehydratase	101
2919291270	435	79.17	51	431	57	303	1.7e-44	145.5	COG0501	Zn-dependent protease with chaperone function	302
2919291271	197	97.28	12	195	3	181	3.9e-84	274.8	COG1949	Oligoribonuclease (3'-5' exoribonuclease)	184
2919291272	623	74.62	30	516	28	415	3.0e-129	425.2	COG0513	Superfamily II DNA and RNA helicase	513
2919291273	490	50	11	149	94	214	1.9e-14	12	COG2202	PAS domain	232
2919291273	490	71.49	118	321	70	242	1.9e-14	38.2	COG2202	PAS domain	232
2919291273	490	91.8	309	485	7	174	3.9e-37	121.3	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2919291274	410	54.05	217	409	5	211	2.3e-40	28.5	COG0477	MFS family permease	338
2919291274	410	71.28	8	247	7	279	2.3e-40	108.6	COG0477	MFS family permease	338
2919291276	731	92.28	95	562	17	482	1.0e-81	269	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
2919291277	263	90.91	1	243	2	241	6.0e-19	62.5	COG1192	Cellulose biosynthesis protein BcsQ	259
2919291280	1305	30.16	26	201	236	346	3.4e-21	9.3	COG0457	Tetratricopeptide (TPR) repeat	291
2919291280	1305	39.95	120	375	90	236	3.4e-21	14.6	COG0457	Tetratricopeptide (TPR) repeat	291
2919291280	1305	64.13	578	885	26	261	3.4e-21	14.9	COG0457	Tetratricopeptide (TPR) repeat	291
2919291280	1305	65.22	349	591	104	343	3.4e-21	44.3	COG0457	Tetratricopeptide (TPR) repeat	291
2919291281	384	91.39	19	380	24	352	9.2e-87	285.3	COG3405	Endo-1,4-beta-D-glucanase Y	360
2919291284	294	98.25	6	288	2	282	5.1e-98	321.9	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
2919291285	293	39.66	48	291	15	131	5.0e-06	20.4	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2919291286	325	28.44	4	74	17	78	3.9e-36	14.4	COG0516	IMP dehydrogenase/GMP reductase	170
2919291286	325	88.53	125	316	1	193	3.9e-36	94.9	COG0516	IMP dehydrogenase/GMP reductase	170
2919291288	824	99.25	30	724	2	667	0.0e+00	718.7	COG0210	Superfamily I DNA or RNA helicase	655
2919291289	650	63.24	186	644	210	603	1.3e-19	63.1	COG3211	Secreted phosphatase, PhoX family	616
2919291292	317	94.03	1	315	5	319	3.4e-73	240.3	COG2334	Ser/Thr protein kinase RdoA involved in Cpx stress response, MazF antagonist	331
2919291294	932	94.19	1	310	7	314	2.9e-81	267	COG0258	5'-3' exonuclease	310
2919291294	932	99.66	334	932	3	597	0.0e+00	784.8	COG0749	DNA polymerase I - 3'-5' exonuclease and polymerase domains	593
2919291296	301	97.67	45	268	3	212	3.0e-53	174.6	COG0625	Glutathione S-transferase	211
2919291297	210	93.02	2	209	2	201	8.1e-43	140.8	COG0625	Glutathione S-transferase	211
2919291298	309	98.34	1	304	1	296	1.8e-48	159.9	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919291299	404	92.78	1	402	5	364	1.3e-72	232.5	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2919291300	296	95.76	1	276	7	277	2.0e-57	188.8	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2919291301	270	96.96	11	252	3	225	2.5e-41	136	COG1794	Aspartate/glutamate racemase	230
2919291302	330	90.46	9	307	21	276	2.4e-43	142.4	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2919291303	296	92.75	1	278	1	256	8.2e-29	94.8	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
2919291304	796	20.25	24	166	107	155	2.3e-25	15.8	COG2202	PAS domain	232
2919291304	796	55.79	467	620	107	241	2.3e-25	31.9	COG2202	PAS domain	232
2919291304	796	57.44	322	478	102	240	2.3e-25	24.3	COG2202	PAS domain	232
2919291304	796	71.07	132	344	70	241	2.3e-25	24.2	COG2202	PAS domain	232
2919291304	796	98.36	608	792	4	183	4.8e-53	171.7	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2919291305	298	98.31	58	297	3	235	1.2e-76	251	COG0412	Dienelactone hydrolase	236
2919291306	280	93.75	1	277	9	263	8.9e-34	111	COG0428	Zinc transporter ZupT	266
2919291307	610	31.02	491	604	208	310	7.2e-87	5.1	COG0003	Anion-transporting ATPase, ArsA/GET3 family	322
2919291307	610	34.64	188	311	195	309	7.2e-87	17.9	COG0003	Anion-transporting ATPase, ArsA/GET3 family	322
2919291307	610	46.39	17	183	2	155	7.2e-87	165.7	COG0003	Anion-transporting ATPase, ArsA/GET3 family	322
2919291307	610	46.99	338	503	4	159	7.2e-87	94	COG0003	Anion-transporting ATPase, ArsA/GET3 family	322
2919291308	249	98.79	1	249	2	246	2.9e-56	185.2	COG3279	DNA-binding response regulator, LytR/AlgR family	244
2919291309	418	40.1	79	379	208	365	6.5e-04	12.7	COG0642	Signal transduction histidine kinase	336
2919291310	489	99.13	20	489	3	457	0.0e+00	635.5	COG0165	Argininosuccinate lyase	459
2919291311	329	97.81	9	328	7	318	1.9e-66	218.4	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2919291312	485	91.09	7	310	16	291	2.6e-52	171.4	COG3452	Extracellular (periplasmic) sensor domain CHASE (specificity unknown)	297
2919291314	705	97.21	30	534	7	493	0.0e+00	719.4	COG0753	Catalase	496
2919291315	2000	9.98	1804	1999	1468	1630	3.7e-91	45.2	COG2373	Uncharacterized conserved protein YfaS, alpha-2-macroglobulin family	1621
2919291315	2000	21.56	1145	1519	833	1184	3.7e-91	119.7	COG2373	Uncharacterized conserved protein YfaS, alpha-2-macroglobulin family	1621
2919291315	2000	32.88	509	1121	291	827	3.7e-91	138.9	COG2373	Uncharacterized conserved protein YfaS, alpha-2-macroglobulin family	1621
2919291317	289	70.42	151	277	4	103	4.0e-29	79.4	COG1803	Methylglyoxal synthase	142
2919291317	289	78.87	7	141	12	123	4.0e-29	13.7	COG1803	Methylglyoxal synthase	142
2919291318	792	94.69	11	778	31	725	3.5e-126	416	COG4953	Membrane carboxypeptidase/penicillin-binding protein PbpC	733
2919291319	762	56.61	433	573	103	239	1.4e-31	62.1	COG2202	PAS domain	232
2919291319	762	59.5	177	442	99	242	1.4e-31	48.5	COG2202	PAS domain	232
2919291319	762	96.72	560	741	6	182	8.8e-53	172.1	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2919291320	388	96.95	10	387	2	351	2.8e-130	428.2	COG1304	FMN-dependent dehydrogenase, includes L-lactate dehydrogenase and type II isopentenyl diphosphate isomerase	360
2919291321	137	79.41	9	131	25	132	4.1e-28	92.2	COG3474	Cytochrome c2	135
2919291322	191	94.62	9	191	4	179	3.8e-40	131.7	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2919291323	263	95	2	261	11	238	1.8e-45	146.1	COG5343	Anti-sigma-K factor RskA	240
2919291325	158	82.71	38	157	9	118	5.9e-14	46.2	COG2346	Truncated hemoglobin YjbI	133
2919291326	254	66.41	16	156	44	128	1.6e-11	38.2	COG3794	Plastocyanin	128
2919291327	327	21.34	158	303	61	95	2.8e-10	10.3	COG2010	Cytochrome c, mono- and diheme variants	150
2919291327	327	57.93	8	160	49	143	2.8e-10	21.5	COG2010	Cytochrome c, mono- and diheme variants	150
2919291328	356	97.01	54	356	2	293	2.2e-35	116.5	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
2919291329	386	98.2	6	377	4	384	1.3e-73	242.6	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2919291330	462	8.6	8	65	150	186	3.5e-32	26.6	COG0446	NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase	415
2919291330	462	73.49	72	442	95	410	3.5e-32	84.6	COG0446	NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase	415
2919291331	98	7.06	14	98	8	76	1.3e-05	17.4	COG3383	Predicted molibdopterin-dependent oxidoreductase YjgC	978
2919291332	267	92.13	3	261	13	258	6.8e-76	248.9	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
2919291333	290	94.79	5	288	5	277	1.1e-81	268.3	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
2919291334	369	98.3	1	350	4	350	1.2e-127	420.1	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
2919291335	284	97.15	9	255	3	241	6.2e-55	179.9	COG1414	DNA-binding transcriptional regulator, IclR family	246
2919291337	305	98.01	10	303	4	298	1.8e-64	212.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919291338	515	96.87	24	504	14	477	0.0e+00	455.5	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2919291339	398	94.33	5	389	7	372	4.1e-58	191.4	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2919291340	305	97.53	4	281	5	280	5.9e-52	170.7	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2919291341	408	96.97	14	407	10	393	1.2e-122	403.8	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
2919291342	561	98.38	8	558	2	547	0.0e+00	548.2	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
2919291343	293	98.34	6	289	2	297	6.3e-56	184.4	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919291344	315	94.02	17	314	13	295	7.5e-39	127.7	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2919291345	435	9.89	24	61	1	37	1.2e-82	32.7	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
2919291345	435	89.04	77	409	33	365	1.2e-82	237.7	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
2919291346	519	81.88	88	518	78	425	4.2e-94	310.3	COG0840	Methyl-accepting chemotaxis protein	408
2919291348	281	12.75	66	116	73	91	7.8e-54	12.8	COG0780	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF, C-terminal domain, T-fold superfamily	149
2919291348	281	98.66	139	281	3	149	7.8e-54	161	COG0780	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF, C-terminal domain, T-fold superfamily	149
2919291350	261	99.21	1	258	1	251	5.9e-96	315	COG3022	Cytoplasmic iron level regulating protein YaaA, DUF328/UPF0246 family	253
2919291351	1034	99.59	1	490	1	487	0.0e+00	657.3	COG1530	Ribonuclease G or E	487
2919291352	290	90.41	1	281	28	291	7.7e-75	246.1	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
2919291353	224	97.3	9	223	5	220	3.3e-48	158.6	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
2919291354	125	95.33	4	117	5	106	5.5e-16	52.5	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
2919291355	348	91.25	40	345	5	296	2.8e-78	257.6	COG0616	Periplasmic serine protease, ClpP class	317
2919291356	258	79.78	3	258	3	219	7.6e-43	140.4	COG0313	16S rRNA C1402 (ribose-2'-O) methylase RsmI	275
2919291357	199	96.91	7	198	3	190	1.0e-57	188.6	COG0424	Predicted house-cleaning NTP pyrophosphatase, Maf/HAM1 superfamily	193
2919291358	182	98.32	1	179	3	178	4.7e-28	92.5	COG1399	Uncharacterized metal-binding protein YceD, DUF177 family	176
2919291359	60	98.25	1	56	1	56	3.9e-24	78.8	COG0333	Ribosomal protein L32	57
2919291360	350	98.53	1	333	1	334	2.3e-125	412.1	COG0416	Fatty acid/phospholipid biosynthesis enzyme	338
2919291361	325	99.08	2	325	2	324	0.0e+00	444.7	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
2919291362	316	95.88	1	314	1	326	2.9e-78	257.3	COG0331	Malonyl CoA-acyl carrier protein transacylase	310
2919291363	249	97.76	6	248	6	267	5.2e-73	239.8	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2919291364	79	97.53	1	78	3	81	4.9e-32	104.1	COG0236	Acyl carrier protein	80
2919291365	414	99.52	2	414	2	413	0.0e+00	528.5	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
2919291366	208	97.31	12	205	4	184	2.4e-51	168.2	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2919291367	219	68.08	16	203	7	151	1.2e-17	58.7	COG3073	Negative regulator of sigma E activity	213
2919291368	300	88.75	1	298	28	311	1.5e-58	192.6	COG3026	Negative regulator of sigma E activity	320
2919291369	448	22.19	353	445	266	346	3.4e-120	30.6	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
2919291369	448	87.95	2	342	38	358	3.4e-120	368.7	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
2919291370	602	98.84	1	602	6	601	0.0e+00	1004.5	COG0481	Translation elongation factor EF-4, membrane-bound GTPase	603
2919291371	324	85.23	96	318	3	152	7.1e-32	101	COG0681	Signal peptidase I	166
2919291373	227	94.49	3	227	10	232	6.5e-67	219.1	COG0571	dsRNA-specific ribonuclease	235
2919291374	334	97.99	36	334	4	295	9.2e-109	357.2	COG1159	GTPase Era, involved in 16S rRNA processing	298
2919291375	254	94.44	4	254	6	243	9.4e-41	133.9	COG1381	Recombinational DNA repair protein (RecF pathway)	251
2919291376	260	97.94	11	253	2	239	3.8e-78	256.1	COG0854	Pyridoxine 5'-phosphate synthase PdxJ	243
2919291377	135	98.43	1	131	1	125	2.3e-36	118.9	COG0736	Phosphopantetheinyl transferase (holo-ACP synthase)	127
2919291378	363	69.54	1	345	4	293	2.0e-85	281.5	COG1472	Periplasmic beta-glucosidase and related glycosidases	397
2919291379	222	48.54	11	184	46	211	3.8e-23	76.2	COG0668	Small-conductance mechanosensitive channel	316
2919291380	344	69.66	7	334	131	433	1.5e-86	284.7	COG3706	Two-component response regulator, PleD family, consists of two REC domains and a diguanylate cyclase (GGDEF) domain	435
2919291381	514	97.45	2	514	13	508	0.0e+00	688.8	COG1190	Lysyl-tRNA synthetase (class II)	502
2919291382	508	95.37	1	506	8	501	8.3e-28	91.1	COG0728	Peptidoglycan biosynthesis protein MviN/MurJ, putative lipid II flippase	518
2919291384	180	77.78	1	179	44	218	2.9e-69	226.8	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
2919291385	599	97.99	1	595	1	537	7.7e-130	428.2	COG0367	Asparagine synthetase B (glutamine-hydrolyzing)	542
2919291387	200	40.86	3	193	54	167	2.9e-08	28.5	COG0500	SAM-dependent methyltransferase	257
2919291390	436	96.27	18	422	12	372	5.1e-97	318.4	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
2919291391	301	92.59	1	301	18	342	5.7e-35	114	COG0673	Predicted dehydrogenase	342
2919291392	355	98.85	6	353	2	344	2.3e-125	412.2	COG2089	Sialic acid synthase SpsE, contains C-terminal SAF domain	347
2919291393	516	80.21	347	513	14	163	6.1e-13	42.6	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
2919291393	516	99.06	3	349	3	317	1.6e-38	125.7	COG3980	Spore coat polysaccharide biosynthesis protein SpsG, predicted glycosyltransferase	318
2919291394	234	97.81	1	228	4	226	9.3e-52	169.8	COG1083	CMP-N-acetylneuraminic acid synthetase	228
2919291395	388	97.87	1	388	6	372	6.8e-114	375	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
2919291396	336	49.42	1	330	260	556	9.0e-111	365.5	COG1086	NDP-sugar epimerase, includes UDP-GlcNAc-inverting 4,6-dehydratase FlaA1 and capsular polysaccharide biosynthesis protein EpsC	588
2919291397	604	98.17	12	604	2	591	0.0e+00	583.7	COG1086	NDP-sugar epimerase, includes UDP-GlcNAc-inverting 4,6-dehydratase FlaA1 and capsular polysaccharide biosynthesis protein EpsC	588
2919291398	211	90.05	1	208	7	205	3.7e-37	122.5	COG2802	Uncharacterized protein, similar to the N-terminal domain of Lon protease	221
2919291399	183	85.42	94	182	10	91	3.5e-34	69.8	COG0762	Uncharacterized conserved protein YggT, Ycf19 family	96
2919291399	183	91.67	1	90	5	92	3.5e-34	47.4	COG0762	Uncharacterized conserved protein YggT, Ycf19 family	96
2919291400	290	96.94	1	290	1	285	2.2e-124	408.5	COG0777	Acetyl-CoA carboxylase beta subunit	294
2919291401	269	99.25	1	269	1	263	8.8e-92	301	COG0159	Tryptophan synthase alpha chain	265
2919291402	427	98.23	5	405	2	390	0.0e+00	659.5	COG0133	Tryptophan synthase beta chain	396
2919291403	266	99.04	29	251	2	208	4.0e-51	167.9	COG0135	Phosphoribosylanthranilate isomerase	208
2919291404	273	95.13	1	271	1	254	2.9e-80	263.5	COG0101	tRNA U38,U39,U40 pseudouridine synthase TruA	266
2919291405	871	98.36	1	871	15	854	2.4e-88	289.5	COG3170	Tfp pilus assembly protein FimV	755
2919291406	376	98.81	2	374	4	335	9.8e-101	331.6	COG0136	Aspartate-semialdehyde dehydrogenase	334
2919291408	357	98.56	1	357	4	346	0.0e+00	454	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
2919291409	216	97.41	1	212	1	188	2.3e-82	269.6	COG0066	3-isopropylmalate dehydratase small subunit	191
2919291410	41	97.73	1	41	2	44	2.8e-16	53.2	COG5510	Predicted small secreted protein	44
2919291411	473	99.3	1	473	3	428	0.0e+00	639.4	COG0065	Homoaconitase/3-isopropylmalate dehydratase large subunit	423
2919291412	325	97.01	12	311	1	292	1.4e-51	170	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919291413	454	96.57	3	452	2	423	4.3e-97	319.3	COG1236	RNA processing exonuclease, beta-lactamase fold, Cft2 family	427
2919291414	380	99.48	1	380	1	383	0.0e+00	500.1	COG0484	DnaJ-class molecular chaperone with C-terminal Zn finger domain	371
2919291415	649	99.01	1	606	6	605	0.0e+00	844.7	COG0443	Molecular chaperone DnaK (HSP70)	579
2919291416	183	90.31	1	183	19	195	1.5e-52	172.5	COG0576	Molecular chaperone GrpE (heat shock protein)	193
2919291417	125	98.21	2	112	1	110	3.1e-41	133.9	COG0360	Ribosomal protein S6	112
2919291418	90	87.38	1	90	9	98	4.4e-18	59.5	COG2965	Primosomal replication protein N	103
2919291419	93	97.47	8	85	3	79	5.4e-29	94.7	COG0238	Ribosomal protein S18	75
2919291420	150	98.65	1	149	1	146	1.9e-51	168.3	COG0359	Ribosomal protein L9	148
2919291421	470	99.77	24	464	1	435	0.0e+00	561.8	COG0305	Replicative DNA helicase	435
2919291423	586	99.77	125	586	2	440	0.0e+00	547.8	COG1875	Predicted ribonuclease YlaK, contains NYN-type RNase and PhoH-family ATPase domains	436
2919291424	161	96.82	1	156	5	156	9.9e-53	172.3	COG1225	Peroxiredoxin	157
2919291425	123	94.49	1	121	7	126	2.3e-30	99.7	COG3737	Uncharacterized conserved protein, contains Mth938-like domain	127
2919291426	415	99.49	8	403	3	396	3.7e-119	392.3	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
2919291428	444	99.1	1	324	1	331	2.8e-113	372.7	COG0460	Homoserine dehydrogenase	333
2919291429	104	52.48	1	77	6	79	1.1e-01	10.5	COG1585	Membrane protein implicated in regulation of membrane protease activity	140
2919291430	476	99.76	1	474	1	418	0.0e+00	466.4	COG0498	Threonine synthase	411
2919291431	189	91.98	1	167	2	150	5.5e-43	140.9	COG1763	Molybdopterin-guanine dinucleotide biosynthesis protein	161
2919291432	413	98.28	1	412	5	404	0.0e+00	435.2	COG0303	Molybdopterin biosynthesis enzyme	404
2919291433	83	100	2	83	1	84	6.6e-23	75.5	COG1977	Molybdopterin converting factor, small subunit	84
2919291434	295	95.99	7	291	3	289	1.3e-76	251.3	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
2919291439	158	96.64	1	150	2	145	7.7e-51	166	COG0314	Molybdopterin synthase catalytic subunit	149
2919291440	88	9.28	2	73	478	527	5.9e-03	9	COG1292	Choline-glycine betaine transporter	537
2919291441	88	97.75	1	88	3	89	3.7e-35	114	COG0184	Ribosomal protein S15P/S13E	89
2919291442	747	99.42	3	696	2	691	0.0e+00	1048.2	COG1185	Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase)	692
2919291443	328	99.7	1	328	1	330	2.5e-93	307.2	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2919291444	249	98.02	2	249	2	248	1.9e-92	303.3	COG0149	Triosephosphate isomerase	251
2919291445	121	82.8	4	106	3	79	8.4e-29	93.4	COG1314	Preprotein translocase subunit SecG	86
2919291447	119	95.9	1	119	5	121	1.7e-48	157.8	COG0838	NADH:ubiquinone oxidoreductase subunit 3 (chain A)	123
2919291448	159	78.35	1	159	16	167	7.7e-84	273.8	COG0377	NADH:ubiquinone oxidoreductase 20 kD subunit (chhain B) or related Fe-S oxidoreductase	194
2919291449	202	92.78	4	187	9	175	3.1e-59	194	COG0852	NADH:ubiquinone oxidoreductase 27 kD subunit (chain C)	176
2919291450	417	97.49	1	417	11	398	0.0e+00	610	COG0649	NADH:ubiquinone oxidoreductase 49 kD subunit (chain D)	398
2919291451	162	92.17	1	159	12	164	5.7e-54	176.1	COG1905	NADH:ubiquinone oxidoreductase 24 kD subunit (chain E)	160
2919291452	451	95.52	17	444	19	423	0.0e+00	620.1	COG1894	NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F)	424
2919291453	710	95.21	1	710	1	696	0.0e+00	652.6	COG1034	NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)	693
2919291454	360	97.9	15	357	5	330	2.5e-129	425.1	COG1005	NADH:ubiquinone oxidoreductase subunit 1 (chain H)	332
2919291455	170	85.14	11	170	7	155	1.4e-53	175.1	COG1143	Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)	172
2919291456	222	99.4	1	176	2	168	5.8e-50	163.1	COG0839	NADH:ubiquinone oxidoreductase subunit 6 (chain J)	166
2919291457	102	98	2	102	3	100	1.2e-37	122	COG0713	NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K)	100
2919291458	677	99.68	10	671	2	616	0.0e+00	728.8	COG1009	NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit	606
2919291459	491	97.79	1	491	5	491	0.0e+00	629.8	COG1008	NADH:ubiquinone oxidoreductase subunit 4 (chain M)	497
2919291460	497	98.53	3	495	4	472	0.0e+00	474.7	COG1007	NADH:ubiquinone oxidoreductase subunit 2 (chain N)	475
2919291462	162	97.18	1	159	1	138	3.2e-45	146.9	COG5319	Uncharacterized protein	142
2919291463	611	99.49	14	611	3	591	0.0e+00	539.6	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
2919291464	256	99.61	1	247	2	254	6.5e-92	301.5	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2919291465	237	99.16	4	237	3	237	7.1e-88	287.9	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2919291466	398	97.27	18	386	2	357	4.6e-48	158	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2919291467	294	97.34	7	294	5	297	5.5e-85	279.6	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2919291468	333	95.36	3	324	10	317	1.7e-82	271.2	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2919291469	390	89.58	18	384	38	355	8.0e-74	242.9	COG5621	Predicted secreted hydrolase	354
2919291470	351	98.01	14	325	5	300	1.4e-77	254.8	COG0031	Cysteine synthase	300
2919291472	885	18.29	743	837	273	347	3.5e-26	21.8	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
2919291472	885	20.24	4	139	27	109	3.5e-26	11	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
2919291472	885	55.12	168	405	183	408	3.5e-26	46.8	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
2919291473	142	73.29	3	142	39	145	2.4e-33	109.2	COG0071	Molecular chaperone IbpA, HSP20 family	146
2919291474	216	91.67	3	216	16	224	3.9e-71	233.2	COG4181	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component	228
2919291475	333	97.08	6	330	5	303	4.4e-106	348.3	COG0324	tRNA A37 N6-isopentenylltransferase MiaA	308
2919291476	413	95.19	11	412	9	384	1.1e-32	107	COG2814	Predicted arabinose efflux permease, MFS family	394
2919291477	460	86.39	27	459	30	378	2.9e-58	191.9	COG1680	CubicO group peptidase, beta-lactamase class C family	390
2919291478	277	22.08	190	275	228	295	2.1e-21	17.2	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
2919291478	277	31.17	48	193	34	129	2.1e-21	51.5	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
2919291479	799	96.65	267	798	10	500	0.0e+00	506.5	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
2919291480	377	95.2	1	367	5	361	0.0e+00	510.6	COG5008	Tfp pilus assembly protein, ATPase PilU	375
2919291481	447	99.76	20	447	2	412	0.0e+00	529.6	COG0334	Glutamate dehydrogenase/leucine dehydrogenase	411
2919291482	387	97.05	11	387	7	269	1.4e-74	245.2	COG0584	Glycerophosphoryl diester phosphodiesterase	257
2919291484	698	99.38	21	697	4	644	0.0e+00	592.2	COG0323	DNA mismatch repair ATPase MutL	638
2919291485	215	91.35	9	214	8	197	2.5e-59	194.2	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
2919291486	79	29.61	8	79	70	122	3.2e-06	21.4	COG3134	Uncharacterized conserved protein YcfJ, contains glycine zipper 2TM domain	179
2919291487	526	91.53	90	524	37	425	8.4e-112	368.8	COG0840	Methyl-accepting chemotaxis protein	408
2919291488	113	69.47	1	113	28	118	9.4e-17	55.4	COG1917	Cupin domain protein related to quercetin dioxygenase	131
2919291489	486	98.5	55	477	4	265	2.0e-75	247.7	COG0860	N-acetylmuramoyl-L-alanine amidase	231
2919291490	180	97.32	31	180	3	147	1.1e-44	146	COG0802	tRNA A37 threonylcarbamoyladenosine biosynthesis protein TsaE	149
2919291491	349	97.65	1	348	7	339	6.6e-129	424	COG1600	Epoxyqueuosine reductase  QueG (queuosine biosynthesis)	337
2919291492	215	93.21	22	214	10	215	7.5e-26	83.9	COG2755	Lysophospholipase L1 or related esterase	216
2919291493	301	96.81	2	301	7	309	4.1e-47	154.8	COG0679	Predicted permease	311
2919291494	321	95.92	1	319	8	313	3.4e-83	273.4	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2919291495	299	97.67	2	299	7	299	1.1e-113	373.5	COG4974	Site-specific recombinase XerD	300
2919291496	320	97.18	1	319	8	317	7.9e-86	282.2	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2919291497	327	98.43	6	326	5	318	9.2e-89	291.7	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2919291498	426	98.53	23	425	4	404	3.2e-71	234.5	COG3434	c-di-GMP-related signal transduction protein, contains EAL and HDOD domains	407
2919291499	421	98.03	20	421	3	401	2.4e-72	238.3	COG3434	c-di-GMP-related signal transduction protein, contains EAL and HDOD domains	407
2919291500	267	97.39	1	267	4	264	3.2e-107	351.9	COG2833	Uncharacterized conserved protein, contains ferritin-like DUF455 domain	268
2919291501	174	96.61	1	174	4	174	9.5e-68	221.3	COG0663	Carbonic anhydrase or acetyltransferase, isoleucine patch superfamily	176
2919291502	330	97.91	2	314	6	286	1.4e-76	251.6	COG1281	Redox-regulated molecular chaperone, HSP33 family	286
2919291504	191	47.98	52	180	15	97	1.4e-03	12.5	COG1056	Nicotinamide mononucleotide adenylyltransferase	172
2919291505	92	72.88	1	92	26	111	5.4e-24	78.5	COG2919	Cell division protein FtsB	117
2919291506	428	99.76	1	427	1	424	0.0e+00	681.3	COG0148	Enolase	423
2919291507	96	100	1	96	1	96	2.0e-33	108.7	COG5470	Uncharacterized conserved protein, DUF1330 family	96
2919291508	285	97.49	1	281	6	277	3.2e-120	394.5	COG2877	3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase	279
2919291509	552	99.63	2	549	1	533	0.0e+00	813.9	COG0504	CTP synthase (UTP-ammonia lyase)	533
2919291510	407	99.25	3	403	2	399	1.3e-127	420.1	COG0452	Phosphopantothenoylcysteine synthetase/decarboxylase	392
2919291511	119	29.52	21	113	105	184	3.8e-04	13.7	COG3716	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID	269
2919291512	148	97.32	1	148	4	148	1.3e-56	184.5	COG0756	dUTPase	148
2919291513	166	72.08	5	165	36	146	1.6e-19	64.2	COG3133	Outer membrane lipoprotein SlyB	154
2919291514	174	86.44	1	166	1	153	1.7e-31	102.9	COG1047	FKBP-type peptidyl-prolyl cis-trans isomerase 2	174
2919291515	376	97.66	1	372	5	380	5.2e-97	319.1	COG2850	Ribosomal protein L16 Arg81 hydroxylase, contains JmjC domain	383
2919291517	96	25.91	18	96	110	180	3.9e-02	8	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
2919291518	260	96.34	1	247	4	266	3.4e-33	109.1	COG1235	Phosphoribosyl 1,2-cyclic phosphodiesterase	269
2919291519	365	97.08	2	365	10	342	4.0e-78	257	COG3317	Uncharacterized lipoprotein	342
2919291520	298	96.66	4	298	5	293	1.7e-109	359.3	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
2919291521	187	50.54	4	183	47	187	9.2e-14	46.3	COG0500	SAM-dependent methyltransferase	257
2919291523	403	87.85	2	394	35	381	5.0e-22	72	COG2814	Predicted arabinose efflux permease, MFS family	394
2919291524	660	99.06	8	660	3	637	0.0e+00	671.6	COG0187	DNA gyrase/topoisomerase IV, subunit B	635
2919291525	284	59.08	28	240	112	290	1.5e-38	127.2	COG0741	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)	296
2919291526	785	86.84	15	782	16	721	0.0e+00	759.9	COG0188	DNA gyrase/topoisomerase IV, subunit A	804
2919291527	600	90.35	99	512	42	425	9.4e-110	362	COG0840	Methyl-accepting chemotaxis protein	408
2919291528	152	89.71	6	152	13	134	7.8e-20	65.3	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
2919291529	855	95.41	504	846	15	305	3.0e-69	225.6	COG2333	Metal-dependent hydrolase, beta-lactamase superfamily II	293
2919291530	504	95.7	1	492	12	478	0.0e+00	692.3	COG2308	Uncharacterized conserved protein, circularly permuted ATPgrasp superfamily	488
2919291531	48	7.35	1	44	1	23	2.0e-11	38.2	COG2307	Uncharacterized conserved protein, Alpha-E superfamily	313
2919291532	308	95.21	1	308	12	309	3.0e-91	300.3	COG2307	Uncharacterized conserved protein, Alpha-E superfamily	313
2919291533	93	52.94	13	93	10	81	1.3e-33	110.3	COG4628	Uncharacterized conserved protein, DUF2132 family	136
2919291534	305	98.34	2	301	3	298	4.3e-73	240.8	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919291535	293	86.48	3	290	36	310	5.2e-54	177.9	COG0657	Acetyl esterase/lipase	312
2919291536	420	96.92	9	397	11	388	2.4e-61	201.9	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2919291537	1077	99.9	2	1039	1	1013	0.0e+00	1195.7	COG0841	Multidrug efflux pump subunit AcrB	1009
2919291538	498	98.26	29	494	1	452	4.4e-110	362.6	COG1538	Outer membrane protein TolC	457
2919291539	390	94.44	2	390	20	393	2.2e-97	320.6	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
2919291540	478	98.54	6	477	2	473	0.0e+00	536.3	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2919291542	240	69.37	12	237	101	331	7.3e-33	105.6	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
2919291543	322	99.17	5	322	4	360	1.4e-37	121.9	COG3203	Outer membrane protein (porin)	354
2919291544	729	99.37	11	729	6	795	2.0e-104	345	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2919291547	400	88.49	3	393	5	396	5.9e-67	219.5	COG3182	Uncharacterized iron-regulated membrane protein	442
2919291549	724	98.27	1	724	13	749	2.2e-113	373.8	COG4774	Outer membrane receptor for monomeric catechols	750
2919291551	607	95.49	35	469	5	427	3.7e-46	152.2	COG3182	Uncharacterized iron-regulated membrane protein	442
2919291553	158	98.73	1	157	1	155	3.9e-69	225.7	COG2193	Bacterioferritin (cytochrome b1)	157
2919291554	191	95.83	1	191	2	185	2.6e-67	220.2	COG0450	Alkyl hydroperoxide reductase subunit AhpC (peroxiredoxin)	194
2919291555	537	99.23	1	522	1	517	0.0e+00	893.8	COG3634	Alkyl hydroperoxide reductase subunit AhpF	520
2919291556	424	94.57	2	424	14	448	2.2e-25	83.5	COG1538	Outer membrane protein TolC	457
2919291559	1039	99.51	1	1030	1	1025	0.0e+00	992.8	COG3696	Cu/Ag efflux pump CusA	1027
2919291561	273	98.53	1	273	2	270	2.1e-94	310.2	COG1806	Regulator of PEP synthase PpsR, kinase-PPPase family (combines ADP:protein kinase and phosphorylase activities)	273
2919291562	796	98.98	8	796	4	782	0.0e+00	885	COG0574	Phosphoenolpyruvate synthase/pyruvate phosphate dikinase	740
2919291563	114	68.32	25	110	22	90	3.4e-20	66.1	COG4327	Uncharacterized membrane protein	101
2919291564	698	96.08	42	696	6	520	0.0e+00	555.2	COG4147	Na+(or H+)/acetate symporter ActP	529
2919291566	119	52.91	1	118	97	205	4.3e-54	177.8	COG0545	FKBP-type peptidyl-prolyl cis-trans isomerase	205
2919291567	102	82.5	1	102	9	107	3.5e-15	49	COG1733	DNA-binding transcriptional regulator, HxlR family	120
2919291568	300	97.34	4	300	1	293	1.6e-51	170	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919291569	325	64.41	15	296	4	269	8.9e-46	150.7	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
2919291570	404	98.75	5	403	6	401	3.9e-130	428.3	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2919291571	345	98.43	24	343	4	317	1.6e-74	244.8	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2919291572	524	88.47	43	512	50	425	4.8e-103	339.7	COG0840	Methyl-accepting chemotaxis protein	408
2919291573	342	93.1	22	342	15	311	7.0e-63	206.7	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2919291574	792	11.14	274	413	6	43	1.6e-127	4.2	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
2919291574	792	16.42	214	330	43	98	1.6e-127	5.2	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
2919291574	792	99.12	434	790	4	341	1.6e-127	420	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
2919291575	690	72.99	2	480	2	436	0.0e+00	524.2	COG0358	DNA primase (bacterial type)	568
2919291576	368	83.33	14	343	10	324	1.7e-42	139.8	COG0687	Spermidine/putrescine-binding periplasmic protein	363
2919291577	555	93.99	368	555	6	177	2.8e-51	167.1	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2919291578	548	95.77	13	545	15	558	8.2e-110	361.7	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2919291579	297	79.55	143	295	21	125	8.8e-23	74.3	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2919291580	188	82.26	4	178	33	185	3.8e-23	76.5	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
2919291581	209	93.68	7	169	2	164	5.9e-39	127.8	COG3576	Predicted flavin-nucleotide-binding protein, pyridoxine 5'-phosphate oxidase superfamily	173
2919291582	251	96.91	1	244	5	255	2.3e-19	63.8	COG0730	Uncharacterized membrane protein YfcA	258
2919291583	649	64.46	48	465	87	242	7.2e-21	68.2	COG2202	PAS domain	232
2919291583	649	96.72	452	633	5	181	3.8e-59	193	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2919291584	657	96.64	7	657	21	653	0.0e+00	761.9	COG2015	Alkyl sulfatase BDS1 and related hydrolases, metallo-beta-lactamase superfamily	655
2919291585	330	97.18	9	328	8	317	1.3e-76	251.7	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2919291586	408	97.99	10	408	3	393	4.1e-102	336.3	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2919291587	518	95.95	1	516	15	559	1.5e-103	341.1	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2919291588	331	99	1	313	1	298	1.1e-53	176.8	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919291590	615	97.06	48	615	16	544	0.0e+00	570.6	COG0405	Gamma-glutamyltranspeptidase	539
2919291591	527	99.04	2	527	4	520	0.0e+00	443.3	COG3540	Phosphodiesterase/alkaline phosphatase D	522
2919291592	511	96.17	317	511	7	182	8.8e-53	172.2	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2919291593	324	99.4	1	323	1	329	5.0e-100	329.1	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2919291594	262	97.27	1	250	1	249	7.5e-84	275.2	COG0496	Broad specificity polyphosphatase and 5'/3'-nucleotidase SurE	252
2919291595	260	94.79	49	260	4	203	7.1e-65	212.5	COG2518	Protein-L-isoaspartate O-methyltransferase	209
2919291596	309	95.89	70	309	3	305	2.9e-50	165.7	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
2919291597	346	96.92	28	330	9	291	3.0e-88	290.1	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
2919291598	249	89.67	1	181	8	172	5.6e-58	189.6	COG1386	Chromosome segregation and condensation protein ScpB	184
2919291599	520	97.15	161	403	4	242	8.4e-72	235.2	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
2919291600	141	97.78	2	136	2	133	6.2e-60	195.1	COG0105	Nucleoside diphosphate kinase	135
2919291601	370	99.43	2	354	2	348	0.0e+00	457.2	COG0820	Adenine C2-methylase RlmN of 23S rRNA A2503 and tRNA A37	349
2919291602	277	97.2	15	274	7	249	3.2e-61	201.1	COG3063	Tfp pilus assembly protein PilF	250
2919291603	302	35.74	133	270	167	270	1.7e-23	18.3	COG1426	Cytoskeletal protein RodZ, contains Xre-like HTH and DUF4115 domains	284
2919291603	302	46.74	1	145	3	138	1.7e-23	55.7	COG1426	Cytoskeletal protein RodZ, contains Xre-like HTH and DUF4115 domains	284
2919291604	381	91.35	1	379	27	364	2.8e-123	405.6	COG0821	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase IspG/GcpE	361
2919291605	440	97.92	12	438	3	425	0.0e+00	437	COG0124	Histidyl-tRNA synthetase	429
2919291606	230	98.08	1	211	4	207	9.1e-48	156.8	COG2976	Putative negative regulator of RcsB-dependent stress response	207
2919291607	387	85.86	24	387	49	388	2.3e-28	93.2	COG1520	Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat	370
2919291608	447	99.1	1	443	3	443	0.0e+00	559.4	COG1160	Predicted GTPases	444
2919291609	84	96.1	2	77	2	75	1.6e-37	121.2	COG1923	sRNA-binding regulator protein Hfq	77
2919291610	383	86.65	1	378	6	362	0.0e+00	460	COG2262	50S ribosomal subunit-associated GTPase HflX	411
2919291611	438	97.01	87	393	7	298	8.0e-66	216.3	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
2919291612	302	93.02	1	292	8	287	1.6e-64	212.2	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
2919291613	60	91.94	2	60	1	57	3.1e-20	66.3	COG3242	Uncharacterized conserved protein YjeT, DUF2065 family	62
2919291614	382	98.21	2	381	3	386	7.2e-88	288.8	COG3705	ATP phosphoribosyltransferase regulatory subunit HisZ	390
2919291615	458	99.3	6	456	2	428	0.0e+00	585.4	COG0104	Adenylosuccinate synthase	430
2919291616	174	69.79	5	164	3	136	9.5e-34	110.9	COG2236	Hypoxanthine phosphoribosyltransferase	192
2919291617	37	14.18	1	37	1	37	1.1e-08	28.9	COG2086	Electron transfer flavoprotein, alpha and beta subunits	260
2919291618	442	51.17	5	436	398	833	9.1e-90	289.6	COG3264	Small-conductance mechanosensitive channel	835
2919291619	261	96.6	1	259	10	265	2.6e-66	217.8	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2919291620	301	86.17	1	301	18	316	5.8e-97	318.9	COG0123	Acetoin utilization deacetylase AcuC or a related deacetylase	340
2919291621	306	90.3	1	304	10	307	3.7e-88	289.9	COG0714	MoxR-like ATPase	329
2919291622	347	69.78	54	347	10	300	6.5e-33	108.7	COG1721	Uncharacterized conserved protein, DUF58 family, contains vWF domain	416
2919291623	679	59.76	256	553	75	276	1.8e-31	103.6	COG1305	Transglutaminase-like enzyme, putative cysteine protease	319
2919291624	370	96.25	1	370	9	342	7.5e-89	292.4	COG2951	Membrane-bound lytic murein transglycosylase B	343
2919291625	330	98.69	11	316	4	305	2.9e-87	287.1	COG1131	ABC-type multidrug transport system, ATPase component	293
2919291626	256	86.01	6	255	39	290	1.2e-20	68	COG0842	ABC-type multidrug transport system, permease component	286
2919291627	447	94.81	23	428	9	355	2.4e-37	122.7	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2919291628	132	67.81	10	132	40	138	1.2e-15	51.7	COG0071	Molecular chaperone IbpA, HSP20 family	146
2919291629	401	99.8	17	401	2	510	6.5e-75	247.4	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
2919291630	261	96.46	9	240	2	219	3.2e-83	272.5	COG1136	ABC-type lipoprotein export system, ATPase component	226
2919291631	465	94.1	28	462	7	373	5.5e-50	163.2	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2919291632	452	97.83	1	452	2	451	1.9e-105	347.5	COG1538	Outer membrane protein TolC	457
2919291633	331	83.33	189	327	16	125	2.1e-25	82.2	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2919291634	402	98.09	13	389	5	363	4.8e-41	135	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2919291635	292	98.01	2	292	3	297	2.0e-65	215.4	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2919291636	310	97.52	5	304	7	321	2.6e-51	168.7	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2919291637	253	99.21	1	241	2	253	9.0e-81	264.5	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2919291638	236	99.16	3	235	3	237	2.7e-85	279.4	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2919291639	483	99.58	4	479	2	478	0.0e+00	501.8	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2919291640	346	98.26	3	346	2	339	0.0e+00	431.2	COG0533	tRNA A37 threonylcarbamoyltransferase TsaD	342
2919291641	386	94.81	7	384	9	355	1.9e-68	225.2	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2919291642	208	91.24	13	207	17	193	5.1e-59	193.1	COG3707	Two-component response regulator, AmiR/NasT family, consists of REC and RNA-binding antiterminator (ANTAR) domains	194
2919291643	414	97.91	7	356	5	332	9.2e-76	249.3	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2919291644	269	92.64	6	268	10	248	7.0e-69	226.1	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2919291645	266	98.41	3	264	2	248	4.4e-96	315.3	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2919291646	145	91.41	4	123	15	163	2.5e-25	83.6	COG0517	CBS domain	117
2919291649	339	98.8	1	334	3	330	2.8e-107	352.9	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
2919291650	433	99.47	55	433	1	377	0.0e+00	453.4	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
2919291651	170	77.97	8	169	11	148	2.1e-26	86.3	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
2919291652	173	99.38	13	171	1	160	5.3e-51	166.4	COG3265	Gluconate kinase	161
2919291653	345	98.5	18	345	2	330	2.8e-89	293.8	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
2919291654	549	81.88	68	519	78	425	3.5e-97	320.4	COG0840	Methyl-accepting chemotaxis protein	408
2919291655	404	96.43	1	403	5	409	2.8e-89	293.9	COG2223	Nitrate/nitrite transporter NarK	417
2919291656	585	92.28	2	246	13	263	1.0e-37	123.2	COG0631	Serine/threonine protein phosphatase PrpC	262
2919291657	815	98.38	1	810	1	788	0.0e+00	1125.7	COG1251	NAD(P)H-nitrite reductase, large subunit	793
2919291658	270	10.98	122	261	19	81	1.1e-07	4	COG3850	Signal transduction histidine kinase, nitrate/nitrite-specific	574
2919291658	270	17.6	2	138	10	110	1.1e-07	22.8	COG3850	Signal transduction histidine kinase, nitrate/nitrite-specific	574
2919291659	133	96.26	7	110	3	105	1.1e-26	86.7	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
2919291660	945	77.78	879	941	3	51	3.7e-08	26.1	COG2906	Bacterioferritin-associated ferredoxin	63
2919291660	945	94.44	1	721	45	809	0.0e+00	606.7	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
2919291661	307	90.59	1	306	3	310	1.7e-54	179.1	COG0547	Anthranilate phosphoribosyltransferase	338
2919291662	277	95.08	19	274	4	235	2.1e-81	267.1	COG0007	Uroporphyrinogen-III methylase (siroheme synthase)	244
2919291663	234	30.35	35	208	166	294	2.3e-11	37.6	COG0840	Methyl-accepting chemotaxis protein	408
2919291664	162	94.9	1	151	8	156	5.5e-51	166.4	COG1607	Acyl-CoA hydrolase	157
2919291665	377	89.68	114	376	23	274	1.9e-66	218.8	COG3000	Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily	271
2919291666	160	23.17	77	102	51	69	1.3e-03	3.4	COG5460	Uncharacterized conserved protein, DUF2164 family	82
2919291666	160	30.49	120	158	56	80	1.3e-03	7.9	COG5460	Uncharacterized conserved protein, DUF2164 family	82
2919291667	394	94.81	18	394	9	355	6.6e-44	144.5	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2919291668	740	97.64	3	740	18	720	0.0e+00	595.3	COG4773	Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid	719
2919291669	422	98.28	4	412	4	403	0.0e+00	445.6	COG2081	Predicted flavoprotein YhiN	408
2919291670	1086	65.46	594	1086	218	651	4.1e-114	375	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2919291670	1086	78.51	236	626	53	242	5.3e-19	55.3	COG2202	PAS domain	232
2919291671	70	95.52	1	66	1	64	7.3e-30	97	COG0828	Ribosomal protein S21	67
2919291672	148	99.32	1	147	1	147	7.1e-57	186.1	COG1610	Uncharacterized conserved protein YqeY	148
2919291673	314	98.01	7	300	4	298	1.3e-69	229.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919291674	369	99.14	7	367	2	346	7.0e-126	414	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
2919291676	298	98.01	4	297	1	295	5.6e-54	178	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919291678	141	95.21	5	133	2	140	1.3e-10	36.7	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2919291679	177	36.31	6	134	203	320	6.8e-28	91.5	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
2919291680	253	74.88	2	180	3	160	1.7e-13	44.6	COG2910	Putative NADH-flavin reductase	211
2919291681	480	99.34	37	480	3	455	5.0e-110	362.4	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
2919291682	223	73.26	23	211	26	162	4.8e-41	132.5	COG3028	Ribosomal 50S subunit-associated protein YjgA (function unknown), DUF615 family	187
2919291683	201	97.06	2	182	5	169	7.3e-61	198.6	COG0521	Molybdopterin biosynthesis enzyme MoaB	169
2919291685	260	89.29	1	190	7	181	1.8e-79	259.7	COG1045	Serine acetyltransferase	194
2919291686	270	40.32	1	112	4	103	1.2e-68	101.1	COG0565	tRNA C32,U32 (ribose-2'-O)-methylase TrmJ or a related methyltransferase	242
2919291686	270	54.84	107	270	106	241	1.2e-68	122.9	COG0565	tRNA C32,U32 (ribose-2'-O)-methylase TrmJ or a related methyltransferase	242
2919291687	318	98.07	5	263	2	255	8.1e-87	284.8	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
2919291688	376	96.22	8	374	14	369	2.2e-129	425.7	COG3437	Response regulator c-di-GMP phosphodiesterase, RpfG family, contains REC and HD-GYP domains	360
2919291689	1624	65.48	676	1096	134	391	2.2e-75	248.9	COG0642	Signal transduction histidine kinase	336
2919291689	1624	89.47	1102	1235	6	124	3.8e-63	81.8	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2919291689	1624	91.73	1254	1533	7	128	3.8e-63	122.9	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2919291690	848	64.4	351	848	217	643	9.6e-122	401	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2919291691	891	99.65	3	869	4	854	0.0e+00	941.9	COG0249	DNA mismatch repair ATPase MutS	843
2919291692	275	95.69	1	256	1	244	1.3e-109	359.3	COG3484	Predicted proteasome-type protease	255
2919291693	273	91.19	1	266	24	292	3.0e-21	70.5	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2919291694	273	77.58	10	271	53	270	4.1e-26	86	COG2324	Uncharacterized membrane protein	281
2919291696	593	95.63	401	586	7	181	4.4e-44	144.2	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2919291697	604	95.08	405	596	8	181	5.6e-47	153.7	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2919291698	599	91.8	404	591	10	177	3.6e-46	150.9	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2919291699	495	21.11	303	494	369	467	5.0e-36	11.3	COG0277	FAD/FMN-containing dehydrogenase	459
2919291699	495	42.22	40	271	18	215	5.0e-36	109.5	COG0277	FAD/FMN-containing dehydrogenase	459
2919291700	441	55.37	5	141	105	238	2.4e-23	31	COG2202	PAS domain	232
2919291700	441	75.21	87	270	59	240	2.4e-23	52.3	COG2202	PAS domain	232
2919291700	441	96.72	257	438	6	182	1.4e-52	171.7	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2919291701	297	88.76	40	294	29	257	9.0e-29	92.9	COG3713	Outer membrane scaffolding protein for murein synthesis, MipA/OmpV family	258
2919291702	274	98.9	1	268	3	272	2.0e-101	333.1	COG1968	Undecaprenyl pyrophosphate phosphatase UppP	270
2919291703	136	90.84	1	131	9	127	2.0e-28	93.6	COG5395	Uncharacterized membrane protein	131
2919291706	358	70.89	2	300	8	270	2.0e-25	80.7	COG4188	Predicted dienelactone hydrolase	365
2919291709	291	97.18	5	291	3	243	5.3e-58	190.4	COG3279	DNA-binding response regulator, LytR/AlgR family	244
2919291710	487	97.39	19	487	4	451	1.5e-123	407.2	COG1538	Outer membrane protein TolC	457
2919291711	1051	99.8	2	1021	2	1013	0.0e+00	1107.7	COG0841	Multidrug efflux pump subunit AcrB	1009
2919291713	1036	99.8	2	1024	1	1012	0.0e+00	1120.2	COG0841	Multidrug efflux pump subunit AcrB	1009
2919291714	594	96.92	15	413	8	385	2.3e-66	219	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2919291715	213	96.15	1	213	7	206	1.7e-48	158.8	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
2919291716	186	56.54	1	178	20	192	7.3e-25	82.3	COG1131	ABC-type multidrug transport system, ATPase component	293
2919291717	305	95.02	5	302	11	296	2.1e-44	146.3	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2919291718	336	97.2	7	325	3	314	1.1e-38	127.7	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2919291719	311	85.49	8	307	39	315	9.5e-59	193.3	COG0385	Predicted Na+-dependent transporter	319
2919291720	452	30.27	248	422	287	421	8.8e-61	7.8	COG2072	Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD	443
2919291720	452	47.98	16	265	12	225	8.8e-61	191.4	COG2072	Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD	443
2919291721	276	82.46	1	250	3	223	2.7e-40	132.9	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2919291722	250	97.15	7	250	5	243	2.0e-60	197.9	COG1414	DNA-binding transcriptional regulator, IclR family	246
2919291724	322	76.15	42	321	19	216	5.2e-27	89.3	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2919291725	222	26.99	68	190	22	65	3.6e-11	37	COG2062	Phosphohistidine phosphatase SixA	163
2919291727	845	72.84	432	840	105	391	7.0e-73	240.8	COG0642	Signal transduction histidine kinase	336
2919291728	270	92.23	4	269	6	266	3.9e-33	109.2	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2919291729	258	54.86	17	246	163	365	7.2e-69	226.7	COG3437	Response regulator c-di-GMP phosphodiesterase, RpfG family, contains REC and HD-GYP domains	360
2919291730	123	48.71	2	119	1	113	7.6e-35	114.5	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2919291731	224	92.48	55	222	6	128	1.2e-15	51.7	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2919291732	244	93.23	1	159	5	128	6.0e-19	62.3	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2919291733	255	95.76	3	240	3	228	9.5e-54	176.3	COG3300	MHYT domain, NO-binding membrane sensor	236
2919291734	229	97.21	1	224	1	209	1.3e-42	140.2	COG0625	Glutathione S-transferase	211
2919291735	167	96.62	2	155	4	146	5.2e-42	137.7	COG0394	Protein-tyrosine-phosphatase	139
2919291736	357	97.01	7	344	4	295	1.3e-78	258.6	COG1975	Xanthine and CO dehydrogenase maturation factor, XdhC/CoxF family	278
2919291737	210	97.95	1	152	1	143	1.0e-39	129.7	COG3427	Carbon monoxide dehydrogenase subunit G	146
2919291738	410	96.98	7	409	9	393	2.4e-78	258.2	COG3552	Uncharacterized conserved protein, contains von Willebrand factor type A (vWA) domain	395
2919291739	306	80	3	305	10	273	2.6e-64	211.6	COG0714	MoxR-like ATPase	329
2919291740	263	98.25	1	263	1	281	1.8e-71	235.5	COG1319	CO or xanthine dehydrogenase, FAD-binding subunit	284
2919291741	795	99.19	7	792	6	744	0.0e+00	734.7	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
2919291742	156	96.15	1	154	2	151	8.1e-67	218	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
2919291743	382	8.33	307	378	555	605	3.8e-58	33.8	COG3284	Transcriptional regulator of acetoin/glycerol metabolism	606
2919291743	382	40.36	11	294	12	258	3.8e-58	156.2	COG3284	Transcriptional regulator of acetoin/glycerol metabolism	606
2919291744	148	90.91	1	138	1	120	2.3e-18	60.9	COG0789	DNA-binding transcriptional regulator, MerR family	124
2919291746	202	17.37	1	47	6	42	3.3e-30	14.3	COG0655	Multimeric flavodoxin WrbA	207
2919291746	202	65.26	40	187	73	211	3.3e-30	84.7	COG0655	Multimeric flavodoxin WrbA	207
2919291748	354	96.5	11	354	9	339	2.1e-109	359.8	COG0798	Arsenite efflux pump ArsB, ACR3 family	342
2919291749	168	95.95	3	142	4	145	2.5e-30	99.6	COG0394	Protein-tyrosine-phosphatase	139
2919291750	166	80.14	1	115	5	121	3.4e-03	10.3	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2919291751	108	76.27	1	96	15	104	1.1e-10	36.3	COG0640	DNA-binding transcriptional regulator, ArsR family	110
2919291752	565	81.36	19	245	18	209	2.9e-04	13.6	COG3300	MHYT domain, NO-binding membrane sensor	236
2919291752	565	94.55	263	531	11	253	3.7e-67	219.9	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
2919291753	374	47.94	4	273	4	189	4.4e-18	59.6	COG1748	Saccharopine dehydrogenase, NADP-dependent	389
2919291756	164	99.35	2	162	2	155	9.0e-44	143.5	COG5528	Uncharacterized membrane protein	155
2919291757	565	97.66	7	525	6	505	3.4e-128	422.8	COG0661	Predicted unusual protein kinase regulating ubiquinone biosynthesis, AarF/ABC1/UbiB family	517
2919291758	277	96.25	5	277	9	265	1.5e-38	126	COG0725	ABC-type molybdate transport system, periplasmic component	258
2919291759	241	86.07	1	241	34	274	5.8e-98	321.6	COG2998	ABC-type tungstate transport system, permease component	280
2919291760	242	97.93	8	240	3	239	3.4e-50	163.2	COG1126	ABC-type polar amino acid transport system, ATPase component	240
2919291761	245	97.36	2	228	5	225	6.8e-68	222.5	COG4662	ABC-type tungstate transport system, periplasmic component	227
2919291762	362	65.65	2	114	23	108	4.7e-18	59.1	COG2005	DNA-binding transcriptional regulator ModE (molybdenum-dependent)	130
2919291762	362	97.76	109	341	4	221	1.8e-51	168.7	COG1910	Periplasmic molybdate-binding protein/domain	223
2919291763	206	96.15	1	182	1	175	3.2e-70	229.5	COG4665	TRAP-type mannitol/chloroaromatic compound transport system, small permease component	182
2919291764	595	97.99	3	534	3	440	0.0e+00	660.1	COG4664	TRAP-type mannitol/chloroaromatic compound transport system, large permease component	447
2919291765	360	99.72	1	357	1	362	0.0e+00	508	COG4663	TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component	363
2919291766	631	98.56	4	627	3	620	0.0e+00	903.9	COG1154	Deoxyxylulose-5-phosphate synthase	627
2919291767	324	97.26	17	324	8	326	2.0e-80	263.7	COG0142	Geranylgeranyl pyrophosphate synthase	322
2919291768	80	76.54	3	80	7	68	1.4e-19	64.1	COG1722	Exonuclease VII small subunit	81
2919291769	384	97.34	9	383	3	368	5.9e-58	191.1	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
2919291770	303	96.01	1	296	8	296	3.3e-27	89.7	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2919291771	301	96.17	1	301	10	285	1.2e-71	229.9	COG2897	3-mercaptopyruvate sulfurtransferase SseA, contains two rhodanese domains	285
2919291774	193	73.03	49	189	17	127	7.4e-07	22.6	COG5616	TolB amino-terminal domain (function unknown)	152
2919291776	430	94.44	64	430	11	350	4.4e-66	217.4	COG0628	Predicted PurR-regulated permease PerM	355
2919291778	929	99.67	1	929	4	913	0.0e+00	1126.8	COG2352	Phosphoenolpyruvate carboxylase	910
2919291779	310	97.07	6	309	3	300	3.8e-111	365.2	COG0181	Porphobilinogen deaminase	307
2919291780	275	97.6	5	275	2	245	2.3e-34	112.8	COG1587	Uroporphyrinogen-III synthase	248
2919291781	376	85.61	4	375	19	357	1.4e-51	169.9	COG2959	Uncharacterized conserved protein HemX (no evidence of involvement in heme biosynthesis)	391
2919291782	425	96.5	1	425	1	386	1.2e-36	119.7	COG3071	Uncharacterized conserved protein HemY, contains two TPR repeats	400
2919291783	190	97.79	8	190	3	179	4.9e-51	167.2	COG3038	Cytochrome b561	181
2919291784	191	92.75	3	185	11	189	1.3e-37	123.4	COG2353	Polyisoprenoid-binding periplasmic protein YceI	192
2919291785	191	99.48	1	191	1	192	1.5e-55	182.1	COG2353	Polyisoprenoid-binding periplasmic protein YceI	192
2919291786	472	79.25	1	469	92	515	3.5e-99	326.6	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
2919291787	207	97.95	20	152	2	144	2.9e-18	61.6	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2919291788	619	90.06	95	455	22	302	2.2e-25	82.9	COG0501	Zn-dependent protease with chaperone function	302
2919291789	965	99.66	13	965	2	881	0.0e+00	1191.1	COG0525	Valyl-tRNA synthetase	877
2919291790	295	97.93	4	295	3	286	1.2e-121	399.6	COG1210	UTP-glucose-1-phosphate uridylyltransferase	291
2919291791	75	91.25	1	75	6	78	1.7e-23	76.8	COG0425	TusA-related sulfurtransferase	78
2919291792	194	48.59	1	158	113	250	1.1e-22	75.2	COG2816	NADH pyrophosphatase NudC, Nudix superfamily	279
2919291793	300	99.01	2	296	3	301	3.3e-109	358.8	COG0031	Cysteine synthase	300
2919291795	309	88.06	38	308	24	318	7.3e-17	56.1	COG0582	Integrase	309
2919291796	152	25.68	26	150	232	326	2.7e-03	11.6	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2919291799	159	64.43	1	159	4	166	1.4e-53	176.5	COG3926	Lysozyme family protein	252
2919291800	81	9.57	6	62	223	267	1.6e-03	11.8	COG1282	NAD/NADP transhydrogenase beta subunit	463
2919291805	323	18.3	264	317	82	109	2.2e-02	3.7	COG3918	Uncharacterized membrane protein	153
2919291805	323	56.21	102	208	54	139	2.2e-02	5.6	COG3918	Uncharacterized membrane protein	153
2919291815	349	30.24	3	347	104	331	5.2e-01	3.1	COG0643	Chemotaxis protein histidine kinase CheA	716
2919291816	94	18.96	5	89	246	307	2.1e-03	11.3	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
2919291821	127	32.26	5	127	116	175	7.6e-04	13.6	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2919291829	322	55.73	51	306	190	432	5.9e-12	38.9	COG0305	Replicative DNA helicase	435
2919291839	227	79.8	19	204	19	180	2.8e-19	63.5	COG1974	SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase)	201
2919291852	153	100	1	153	1	171	3.7e-49	161.8	COG0629	Single-stranded DNA-binding protein	167
2919291862	70	24.08	3	68	65	110	1.7e-05	18.9	COG4420	Uncharacterized membrane protein	191
2919291865	301	95.35	11	301	8	294	7.6e-31	101.8	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
2919291866	63	57.14	2	63	29	68	1.2e-05	19.5	COG3311	Predicted DNA-binding transcriptional regulator AlpA	70
2919291871	314	98.01	6	310	3	297	9.9e-57	187.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919291872	398	98.25	8	396	4	395	2.8e-109	359.9	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2919291873	424	98.75	1	424	6	401	0.0e+00	486.5	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2919291874	533	91.06	35	507	39	425	1.1e-110	365.1	COG0840	Methyl-accepting chemotaxis protein	408
2919291875	182	93.42	9	163	10	151	3.3e-45	147.8	COG0054	6,7-dimethyl-8-ribityllumazine synthase (Riboflavin synthase beta chain)	152
2919291878	324	98.34	20	321	2	297	1.8e-44	147	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919291879	339	95.48	3	335	7	323	1.2e-105	347.6	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
2919291880	593	98.27	1	579	8	575	0.0e+00	581.2	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
2919291881	409	99.21	17	404	4	379	0.0e+00	505.3	COG3970	Fumarylacetoacetate (FAA) hydrolase family protein	379
2919291882	189	89.27	2	173	14	171	1.3e-42	139.4	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
2919291883	426	99.47	47	425	2	378	0.0e+00	466.8	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
2919291884	213	99.53	1	213	1	210	3.4e-73	240.2	COG2910	Putative NADH-flavin reductase	211
2919291885	300	98.67	2	297	2	298	2.1e-67	222.2	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919291886	100	90.57	1	97	2	97	1.7e-20	67.2	COG2329	Heme-degrading monooxygenase HmoA and related ABM domain proteins	105
2919291887	319	91.73	183	319	7	128	9.9e-20	64.1	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2919291887	319	95.76	3	174	3	160	1.1e-41	136.1	COG0835	Chemotaxis signal transduction protein	165
2919291890	314	95.02	16	314	4	308	1.6e-28	94.3	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2919291891	350	85.44	3	101	12	99	3.5e-14	46.1	COG0633	Ferredoxin	102
2919291891	350	96.89	99	343	8	256	9.2e-62	202.5	COG0543	NAD(P)H-flavin reductase	252
2919291892	740	98.18	18	725	11	603	0.0e+00	475.8	COG4191	Signal transduction histidine kinase regulating C4-dicarboxylate transport system	603
2919291893	228	95.54	12	220	3	195	1.6e-54	178.7	COG4566	Two-component response regulator, FixJ family, consists of REC and HTH domains	202
2919291894	326	97.81	3	324	5	316	7.5e-77	252.7	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2919291895	175	88.82	10	162	2	144	4.1e-53	173.5	COG0801	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase	160
2919291896	532	97.83	36	466	4	409	1.2e-95	315.4	COG0617	tRNA nucleotidyltransferase/poly(A) polymerase	412
2919291897	240	93.4	5	230	5	202	8.6e-52	169.7	COG0560	Phosphoserine phosphatase	212
2919291898	234	16.63	1	86	93	164	2.5e-36	38.3	COG0593	Chromosomal replication initiation ATPase DnaA	408
2919291898	234	30.95	91	234	201	334	2.5e-36	80.1	COG0593	Chromosomal replication initiation ATPase DnaA	408
2919291899	405	43.86	215	402	22	189	7.8e-24	24.1	COG0477	MFS family permease	338
2919291899	405	60.05	8	246	4	233	7.8e-24	56.5	COG0477	MFS family permease	338
2919291900	349	96.81	7	349	4	337	0.0e+00	457.9	COG0150	Phosphoribosylaminoimidazole (AIR) synthetase	345
2919291901	368	90.56	21	367	15	340	2.7e-11	36.5	COG0628	Predicted PurR-regulated permease PerM	355
2919291902	369	84.35	78	369	46	309	7.8e-46	150.1	COG3509	Poly(3-hydroxybutyrate) depolymerase	312
2919291903	186	89.32	1	178	4	187	1.5e-25	83.7	COG1335	Nicotinamidase-related amidase	205
2919291904	204	57.85	1	199	5	192	1.3e-44	146.8	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
2919291905	331	95.08	1	331	5	313	3.3e-65	214.6	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
2919291906	168	45.71	5	164	18	166	3.8e-22	73.2	COG2203	GAF domain	175
2919291907	129	50	7	129	2	117	1.9e-07	25	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2919291908	304	85.93	5	274	37	268	2.4e-116	382.2	COG2326	Polyphosphate kinase 2, PPK2 family	270
2919291909	346	90.55	27	344	25	321	4.5e-45	148.1	COG0598	Mg2+ and Co2+ transporter CorA	322
2919291910	282	66.21	143	248	6	101	1.7e-02	10.7	COG3212	Uncharacterized membrane protein YkoI	144
2919291911	283	94.44	9	282	10	264	1.2e-62	205.8	COG2912	Regulator of sirC expression, contains transglutaminase-like and TPR domains	269
2919291912	509	96.72	1	509	17	517	0.0e+00	517.3	COG0728	Peptidoglycan biosynthesis protein MviN/MurJ, putative lipid II flippase	518
2919291913	100	94.32	1	97	5	87	5.3e-28	91.8	COG0268	Ribosomal protein S20	88
2919291916	398	96.79	1	398	8	399	0.0e+00	486.9	COG4992	Acetylornithine/succinyldiaminopimelate/putrescine aminotransferase	404
2919291917	309	98.39	1	305	5	310	2.3e-117	386	COG0078	Ornithine carbamoyltransferase	310
2919291919	226	96.15	9	222	8	207	3.6e-47	154.8	COG4339	Predicted metal-dependent phosphohydrolase, HD superfamily	208
2919291920	641	24.77	13	194	4	165	0.0e+00	203.5	COG0370	Fe2+ transport system protein B	653
2919291920	641	64.83	181	640	229	652	0.0e+00	453.8	COG0370	Fe2+ transport system protein B	653
2919291921	112	92	22	102	5	73	4.4e-17	56.1	COG1918	Fe2+ transport system protein FeoA	75
2919291922	435	45.57	177	232	25	60	7.8e-03	5.6	COG4238	Outer membrane murein-binding lipoprotein Lpp	78
2919291922	435	58.23	116	189	25	70	7.8e-03	7.3	COG4238	Outer membrane murein-binding lipoprotein Lpp	78
2919291923	614	89.73	2	600	69	671	7.5e-87	283.4	COG1506	Dipeptidyl aminopeptidase/acylaminoacyl peptidase	620
2919291924	291	100	1	285	1	286	8.7e-76	249.1	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
2919291925	221	98.71	1	221	1	229	6.7e-66	216.2	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2919291926	474	87.82	82	474	43	388	2.8e-55	182.8	COG0642	Signal transduction histidine kinase	336
2919291927	122	58.45	8	116	10	92	2.8e-13	44.4	COG0727	Fe-S-cluster containining protein	132
2919291928	218	97.72	7	217	3	216	1.1e-44	146.4	COG1878	Kynurenine formamidase	218
2919291929	442	98.77	1	432	5	406	0.0e+00	542.3	COG3844	Kynureninase	407
2919291930	296	100	35	296	1	262	5.2e-128	420.4	COG3483	Tryptophan 2,3-dioxygenase (vermilion)	262
2919291934	120	65.49	6	109	23	96	5.6e-06	20.2	COG3895	Membrane-bound inhibitor of C-type lysozyme	112
2919291935	410	49.09	206	410	8	195	1.8e-15	9	COG0477	MFS family permease	338
2919291935	410	71.54	13	252	3	276	1.8e-15	42.9	COG0477	MFS family permease	338
2919291937	128	91.67	1	117	1	121	3.0e-23	76.8	COG0789	DNA-binding transcriptional regulator, MerR family	124
2919291938	543	95.97	42	541	7	482	0.0e+00	702.5	COG2719	Stage V sporulation protein SpoVR/YcgB, involved in spore cortex formation (function unknown)	495
2919291939	422	98.35	1	422	4	420	0.0e+00	496.2	COG2718	Uncharacterized conserved protein YeaH/YhbH, required for sporulation, DUF444 family	423
2919291940	640	99.85	1	640	1	649	0.0e+00	942.6	COG2766	Predicted Ser/Thr protein kinase	649
2919291941	403	95.93	1	396	2	378	1.0e-56	187.3	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2919291942	837	60.66	4	184	3	130	2.6e-03	10.8	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2919291942	837	65.01	342	836	215	645	1.0e-125	414.4	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2919291943	1110	49.17	388	516	100	218	7.7e-44	30.3	COG2202	PAS domain	232
2919291943	1110	59.5	123	404	99	242	7.7e-44	45.9	COG2202	PAS domain	232
2919291943	1110	62.81	479	655	91	242	7.7e-44	79.2	COG2202	PAS domain	232
2919291943	1110	66.06	620	1101	204	641	1.6e-121	400.4	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2919291944	971	98.74	21	970	11	869	0.0e+00	1183.2	COG1048	Aconitase A	861
2919291946	291	45.38	28	154	2	60	2.8e-11	38.1	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2919291947	100	80.47	1	99	14	116	8.9e-20	65.8	COG2916	DNA-binding protein H-NS	128
2919291948	280	96.84	69	264	2	154	4.5e-14	47.3	COG0639	Diadenosine tetraphosphatase ApaH/serine/threonine protein phosphatase, PP2A family	155
2919291949	490	74.42	1	481	28	414	0.0e+00	500.6	COG0513	Superfamily II DNA and RNA helicase	513
2919291950	839	99.28	2	837	5	827	0.0e+00	724.8	COG3127	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component	829
2919291953	116	25.23	2	110	121	203	5.9e-25	82.6	COG0724	 RNA recognition motif (RRM) domain	306
2919291954	313	92.88	19	294	19	266	3.0e-60	193.4	COG1526	Formate dehydrogenase assembly factor FdhD	266
2919291956	409	96.33	172	394	4	213	4.9e-60	196.4	COG2864	Cytochrome b subunit of formate dehydrogenase	218
2919291957	80	50	1	31	1	22	5.3e-04	13.9	COG5510	Predicted small secreted protein	44
2919291958	205	74.15	1	195	11	162	2.2e-46	151.9	COG0437	Fe-S-cluster-containing dehydrogenase component	203
2919291959	988	99.75	34	988	2	809	0.0e+00	659.9	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
2919291961	210	92.16	13	209	7	194	2.3e-38	125.8	COG3381	Cytoplasmic chaperone TorD involved in molybdoenzyme TorA maturation	204
2919291962	689	41.13	580	674	39	89	4.0e-35	24.6	COG1145	Ferredoxin	99
2919291962	689	58.06	272	370	39	110	4.0e-35	46.7	COG1145	Ferredoxin	99
2919291962	689	62.9	150	244	39	116	4.0e-35	33.3	COG1145	Ferredoxin	99
2919291962	689	70.97	516	639	23	110	4.0e-35	46.5	COG1145	Ferredoxin	99
2919291965	961	21.57	6	256	7	217	0.0e+00	153.3	COG3383	Predicted molibdopterin-dependent oxidoreductase YjgC	978
2919291965	961	69.33	252	961	262	939	0.0e+00	688.4	COG3383	Predicted molibdopterin-dependent oxidoreductase YjgC	978
2919291966	670	14.15	210	288	20	79	3.3e-117	42.1	COG1894	NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F)	424
2919291966	670	79.48	299	647	80	416	3.3e-117	340.5	COG1894	NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F)	424
2919291966	670	79.52	28	186	27	158	5.0e-24	78.3	COG1905	NADH:ubiquinone oxidoreductase 24 kD subunit (chain E)	160
2919291967	318	95.35	3	304	3	289	4.6e-42	138.9	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919291968	363	94.06	36	313	15	283	1.4e-93	307.2	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
2919291969	190	47.47	24	190	96	198	4.5e-04	14	COG1787	Endonuclease, HJR/Mrr/RecB family	217
2919291970	428	80.88	9	347	7	264	1.2e-37	124.2	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
2919291971	372	81.23	58	367	28	278	7.4e-37	119.4	COG3386	Sugar lactone lactonase YvrE	307
2919291972	696	71.83	574	691	9	110	1.3e-35	115.2	COG0073	tRNA-binding EMAP/Myf domain	123
2919291972	696	99.11	2	563	3	556	0.0e+00	594.7	COG0143	Methionyl-tRNA synthetase	558
2919291974	213	67.12	12	212	10	205	1.8e-39	129.8	COG1284	Uncharacterized membrane-anchored protein YitT, contains DUF161 and DUF2179 domains	289
2919291975	170	22	88	154	41	73	1.1e-05	14.9	COG2913	Outer membrane protein assembly factor BamE, lipoprotein component of the BamABCDE complex	147
2919291975	170	24.67	21	87	43	79	1.1e-05	3	COG2913	Outer membrane protein assembly factor BamE, lipoprotein component of the BamABCDE complex	147
2919291977	287	95.97	51	286	2	239	1.5e-70	231.9	COG1354	Chromatin segregation and condensation protein Rec8/ScpA/Scc1, kleisin family	248
2919291978	529	96.92	1	527	7	510	0.0e+00	672.5	COG0029	Aspartate oxidase	518
2919291979	211	99.08	1	211	2	216	1.8e-38	126.7	COG0602	Organic radical activating enzyme	212
2919291980	124	67.11	1	115	1	102	9.3e-23	75.4	COG0720	6-pyruvoyl-tetrahydropterin synthase	127
2919291981	126	96.83	2	126	2	123	3.1e-53	173.3	COG0853	Aspartate 1-decarboxylase	126
2919291982	441	98.21	4	441	6	444	0.0e+00	486	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
2919291983	223	91.93	1	217	2	206	2.1e-67	221.2	COG0132	Dethiobiotin synthetase	223
2919291984	406	99.23	9	400	3	389	2.0e-127	419.4	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
2919291985	119	92.91	1	119	1	118	6.0e-25	82.3	COG3232	5-carboxymethyl-2-hydroxymuconate isomerase	127
2919291986	351	98.51	102	348	2	265	7.9e-68	222.9	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2919291989	612	60.39	25	414	178	459	1.1e-95	315.5	COG0147	Anthranilate/para-aminobenzoate synthases component I	462
2919291990	376	96.62	23	358	11	324	4.1e-119	391.5	COG0379	Quinolinate synthase	324
2919291991	282	97.86	6	281	5	278	2.5e-105	345.7	COG0157	Nicotinate-nucleotide pyrophosphorylase	280
2919291992	293	94.78	27	293	6	259	1.5e-99	326.9	COG0413	Ketopantoate hydroxymethyltransferase	268
2919291993	279	98.6	1	279	1	281	5.4e-93	305.4	COG0414	Panthothenate synthetase	285
2919291994	243	92.54	2	237	22	294	4.1e-33	109.5	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2919291995	1167	99.63	284	1167	2	806	0.0e+00	1059.7	COG4196	Uncharacterized conserved protein, DUF2126 family	808
2919291996	881	96.93	43	538	15	487	0.0e+00	515.7	COG2308	Uncharacterized conserved protein, circularly permuted ATPgrasp superfamily	488
2919291996	881	98.72	553	874	2	310	5.5e-46	151.1	COG2307	Uncharacterized conserved protein, Alpha-E superfamily	313
2919291997	328	93.79	1	309	11	327	7.7e-59	194.2	COG1305	Transglutaminase-like enzyme, putative cysteine protease	319
2919291998	319	98.72	1	319	1	309	2.4e-95	314	COG2307	Uncharacterized conserved protein, Alpha-E superfamily	313
2919291999	51	6.71	1	39	1	21	1.5e-10	35.6	COG2307	Uncharacterized conserved protein, Alpha-E superfamily	313
2919292000	510	96.72	1	502	12	483	0.0e+00	698.7	COG2308	Uncharacterized conserved protein, circularly permuted ATPgrasp superfamily	488
2919292001	393	97.13	1	367	1	339	1.8e-116	383	COG4307	Uncharacterized protein	349
2919292002	105	40.1	3	105	117	195	7.7e-21	69.5	COG2823	Osmotically-inducible protein OsmY, contains BON domain	196
2919292003	130	89.42	1	126	6	98	5.0e-09	28.1	COG4575	Membrane-anchored ribosome-binding protein, inhibits growth in stationary phase, ElaB/YqjD/DUF883 family	104
2919292004	54	98.15	1	54	1	53	1.9e-21	70.4	COG5487	Uncharacterized membrane protein YtjA, UPF0391 family	54
2919292005	468	73.07	90	452	102	375	5.5e-61	200.7	COG4585	Signal transduction histidine kinase	365
2919292006	210	99.53	2	210	1	210	1.0e-61	202.5	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2919292007	145	51.66	3	129	4	112	1.6e-13	45	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2919292008	249	97.7	1	248	3	257	6.2e-85	278.7	COG0476	Molybdopterin or thiamine biosynthesis adenylyltransferase	254
2919292009	478	89.22	24	426	35	398	7.6e-125	411.1	COG0793	C-terminal processing protease CtpA/Prc, contains a PDZ domain	406
2919292010	247	99.57	1	230	1	229	5.2e-105	344.5	COG0588	Phosphoglycerate mutase (BPG-dependent)	230
2919292011	135	92.98	29	135	7	112	2.2e-27	89.5	COG0607	Rhodanese-related sulfurtransferase	110
2919292012	85	97.5	2	80	2	79	6.2e-21	68.8	COG0695	Glutaredoxin	80
2919292013	152	91.08	1	150	6	148	3.4e-55	180.2	COG1952	Preprotein translocase subunit SecB	157
2919292014	338	98.78	1	336	2	326	3.4e-105	346.2	COG0240	Glycerol-3-phosphate dehydrogenase	329
2919292015	414	96.46	2	390	15	395	2.5e-116	382.8	COG0019	Diaminopimelate decarboxylase	394
2919292016	316	97.67	14	311	3	296	9.7e-46	151.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919292017	168	96.86	3	161	4	157	2.4e-63	207	COG0669	Phosphopantetheine adenylyltransferase	159
2919292019	421	30.99	85	299	99	173	3.6e-05	16.3	COG2202	PAS domain	232
2919292019	421	78.75	350	419	15	77	2.9e-11	36.3	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2919292021	106	12.79	8	101	62	117	3.3e-02	7.3	COG1253	Hemolysin or related protein, contains CBS domains	429
2919292022	159	74.22	24	155	29	123	4.1e-11	36.9	COG3755	Uncharacterized conserved protein YecT, DUF1311 family	127
2919292024	230	98.4	51	230	2	186	9.7e-45	146.6	COG0742	16S rRNA G966 N2-methylase RsmD	187
2919292025	452	95.65	20	452	14	431	1.8e-78	258.3	COG0612	Predicted Zn-dependent peptidase	438
2919292026	477	96.34	27	463	10	430	1.3e-108	357.5	COG0612	Predicted Zn-dependent peptidase	438
2919292027	474	86.94	151	474	48	360	1.5e-113	373.8	COG0552	Signal recognition particle GTPase	340
2919292028	882	43.39	85	292	99	203	6.2e-31	28.7	COG2202	PAS domain	232
2919292028	882	64.86	412	881	218	647	2.7e-120	396.3	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2919292028	882	83.47	243	444	41	242	6.2e-31	75.7	COG2202	PAS domain	232
2919292030	304	77.42	5	304	67	330	3.9e-85	280.5	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
2919292031	346	94.67	18	345	10	311	8.7e-71	232.9	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2919292032	169	79.05	2	167	43	208	1.6e-51	169.1	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
2919292033	300	92.83	5	300	18	302	3.2e-103	339.6	COG0109	Polyprenyltransferase (heme O synthase)	304
2919292034	394	9.68	17	54	95	127	2.8e-68	3.7	COG1612	Heme A synthase	323
2919292034	394	93.26	37	387	17	334	2.8e-68	224.5	COG1612	Heme A synthase	323
2919292036	240	85.04	1	240	25	240	6.3e-40	131.3	COG3346	Cytochrome oxidase assembly protein ShyY1	252
2919292038	293	94.84	50	293	9	210	1.6e-61	201.1	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
2919292040	211	89.66	1	198	13	194	1.7e-58	189.6	COG3175	Cytochrome c oxidase assembly protein Cox11	195
2919292042	543	90.86	20	542	5	521	0.0e+00	741.8	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
2919292043	389	92.91	7	301	5	240	3.4e-76	249.5	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
2919292044	158	87.8	14	158	19	162	1.9e-27	90.1	COG5488	Uncharacterized membrane protein	164
2919292045	300	29.75	32	275	126	208	1.7e-03	13.2	COG0500	SAM-dependent methyltransferase	257
2919292046	224	95.98	3	222	9	223	5.4e-53	174	COG1040	Predicted amidophosphoribosyltransferases	225
2919292047	175	98.05	1	156	1	151	4.7e-61	199.5	COG0219	tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain	155
2919292048	313	98.34	2	307	2	297	1.0e-61	203.6	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919292049	154	86.79	1	151	18	155	1.2e-48	158.7	COG2030	Acyl dehydratase	159
2919292050	205	22.35	1	76	2	60	1.6e-29	61.2	COG1192	Cellulose biosynthesis protein BcsQ	259
2919292050	205	44.7	72	204	127	244	1.6e-29	35.2	COG1192	Cellulose biosynthesis protein BcsQ	259
2919292051	212	99.04	1	207	1	206	5.2e-53	173.6	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
2919292052	635	66.82	409	587	29	177	9.0e-29	95.4	COG1226	Voltage-gated potassium channel Kch	212
2919292052	635	95	1	401	12	391	1.3e-97	321.3	COG0475	Kef-type K+ transport system, membrane component KefB	397
2919292054	163	40.16	2	150	129	228	2.1e-07	25.5	COG0791	Cell wall-associated hydrolase, NlpC family	197
2919292055	721	98.87	8	721	10	795	1.8e-105	348.6	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2919292056	381	88.04	2	381	5	394	4.6e-47	148.7	COG3182	Uncharacterized iron-regulated membrane protein	442
2919292058	120	17.56	2	117	55	149	1.1e-01	5.2	COG2898	Lysylphosphatidylglycerol synthetase, C-terminal domain, DUF2156 family	538
2919292059	215	93.78	11	215	7	202	9.1e-60	196	COG2860	Uncharacterized membrane protein YeiH	209
2919292060	145	95.59	1	133	4	133	2.1e-43	142	COG0864	Metal-responsive transcriptional regulator, contains CopG/Arc/MetJ DNA-binding domain	136
2919292061	686	96.48	8	686	29	795	1.7e-52	173.4	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2919292062	221	67.05	1	191	17	193	7.0e-12	38.3	COG5266	Uncharacterized conserved protein, contains GH25 family domain	264
2919292063	237	51.18	3	204	132	304	2.3e-27	90.7	COG1305	Transglutaminase-like enzyme, putative cysteine protease	319
2919292064	153	89.36	7	146	12	137	1.6e-22	74	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
2919292065	295	97.67	2	295	2	295	2.3e-70	232	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919292066	200	75	1	199	7	207	5.4e-14	44.3	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2919292067	334	97.18	8	332	7	316	6.6e-103	338.3	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2919292068	247	97.76	5	241	5	266	2.3e-59	195.1	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2919292069	402	99.75	3	402	2	394	0.0e+00	432.8	COG0183	Acetyl-CoA acetyltransferase	392
2919292070	220	95.56	1	220	1	215	7.4e-79	258.7	COG2057	Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit	225
2919292071	233	97.73	2	223	3	217	3.4e-83	272.4	COG1788	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit	220
2919292072	266	99.59	19	263	1	245	2.6e-73	240.2	COG1414	DNA-binding transcriptional regulator, IclR family	246
2919292075	153	37.86	16	149	5	121	1.3e-05	18.4	COG4965	Flp pilus assembly protein TadB	309
2919292077	162	23.66	36	159	116	181	6.9e-05	16.8	COG2035	Uncharacterized membrane protein	276
2919292078	220	51.85	124	217	45	114	1.3e-44	55.8	COG2863	Cytochrome c553	121
2919292078	220	94.81	1	130	1	128	1.3e-44	89.2	COG2863	Cytochrome c553	121
2919292079	284	74.55	1	276	21	266	3.6e-57	188.2	COG0714	MoxR-like ATPase	329
2919292080	83	21.71	3	83	30	90	1.1e-03	13.2	COG4395	Predicted lipid-binding transport protein, Tim44 family	281
2919292081	198	89.84	5	186	18	185	3.3e-30	99.9	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
2919292082	395	99.75	1	395	1	392	0.0e+00	589.1	COG3825	Uncharacterized conserved protein,  contains von Willebrand factor type A (vWA) domain	393
2919292083	645	90.71	57	645	57	603	9.5e-80	261.1	COG0729	Outer membrane translocation and assembly module TamA	594
2919292084	1471	18.97	29	285	5	257	1.2e-75	31.5	COG2911	Autotransporter translocation and assembly factor TamB	1278
2919292084	1471	66.42	307	1470	446	1331	1.2e-75	212.6	COG2911	Autotransporter translocation and assembly factor TamB	1278
2919292086	133	5.61	13	121	655	722	5.5e-03	8.9	COG5283	Phage-related tail protein	1213
2919292087	300	96.23	4	294	10	290	1.4e-103	340	COG5006	Threonine/homoserine efflux transporter RhtA	292
2919292088	163	93.04	3	156	5	151	5.6e-35	114.9	COG1522	DNA-binding transcriptional regulator, Lrp family	154
2919292089	330	96.44	1	322	1	298	1.3e-64	212.6	COG1893	Ketopantoate reductase	307
2919292090	449	93.4	79	449	21	388	6.0e-63	207.9	COG0642	Signal transduction histidine kinase	336
2919292091	219	98.28	1	218	1	228	3.7e-74	243.1	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2919292092	347	98.67	47	344	2	298	7.6e-76	249.2	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
2919292093	507	29.32	404	507	251	357	2.2e-121	47.8	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
2919292093	507	95.34	11	411	13	360	2.2e-121	357.5	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
2919292095	370	98.72	8	370	3	311	3.2e-54	178.4	COG2017	Galactose mutarotase or related enzyme	308
2919292096	309	96.01	6	307	8	296	2.8e-39	129.2	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2919292097	524	12.31	36	94	177	225	0.0e+00	2.5	COG2721	Altronate dehydratase	381
2919292097	524	99.5	109	524	3	398	0.0e+00	478.1	COG2721	Altronate dehydratase	381
2919292098	430	99.47	46	427	1	377	1.1e-124	410.2	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
2919292099	162	87.57	1	160	6	160	5.8e-35	114.3	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
2919292100	325	97.89	1	325	6	330	2.6e-110	362.9	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
2919292101	293	92.23	3	290	22	306	7.5e-72	236	COG3386	Sugar lactone lactonase YvrE	307
2919292102	272	58.88	9	222	4	192	5.0e-31	100.9	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2919292103	242	96.27	5	241	5	236	1.0e-63	208.9	COG2186	DNA-binding transcriptional regulator, FadR family	241
2919292104	479	98.96	2	479	2	475	0.0e+00	535	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2919292106	737	94.34	11	729	19	768	1.3e-68	226.4	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2919292108	597	73.1	217	594	102	389	2.2e-73	242.3	COG0642	Signal transduction histidine kinase	336
2919292110	556	97.43	11	556	8	537	4.6e-127	418.8	COG1178	ABC-type Fe3+ transport system, permease component	540
2919292111	354	98.02	1	353	5	350	7.7e-101	332	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
2919292113	245	74.33	4	241	14	207	2.0e-31	103.3	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
2919292114	431	97.91	1	431	1	422	1.4e-116	384	COG0044	Dihydroorotase or related cyclic amidohydrolase	430
2919292115	320	96.83	10	320	8	312	3.3e-114	375.1	COG0540	Aspartate carbamoyltransferase, catalytic chain	316
2919292116	174	75.42	9	171	28	162	1.5e-39	129.5	COG2065	Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase	179
2919292117	143	95.74	18	143	2	136	4.9e-30	96.9	COG0816	RNase H-fold protein, predicted Holliday junction resolvase in Firmicutes and mycoplasms, involved in anti-termination at Rho-dependent terminators	141
2919292118	199	95.88	1	199	9	194	4.1e-66	216.2	COG1678	Putative transcriptional regulator, AlgH/UPF0301 family	194
2919292119	496	98.92	12	492	5	462	0.0e+00	482.6	COG0415	Deoxyribodipyrimidine photolyase	461
2919292120	399	93.6	20	381	8	358	0.0e+00	446.4	COG5008	Tfp pilus assembly protein, ATPase PilU	375
2919292121	2092	10.34	1300	1413	8	85	0.0e+00	40.2	COG0643	Chemotaxis protein histidine kinase CheA	716
2919292121	2092	23.47	1075	1297	10	186	0.0e+00	22	COG0643	Chemotaxis protein histidine kinase CheA	716
2919292121	2092	42.71	689	1070	5	326	0.0e+00	63.7	COG0643	Chemotaxis protein histidine kinase CheA	716
2919292121	2092	55.17	1414	1942	332	747	0.0e+00	444.2	COG0643	Chemotaxis protein histidine kinase CheA	716
2919292121	2092	61.54	1958	2091	11	122	6.1e-11	35.2	COG4567	Two-component response regulator, ActR/RegA family, consists of REC and Fis-type HTH domains	182
2919292122	762	78.12	425	761	94	425	5.6e-88	290.3	COG0840	Methyl-accepting chemotaxis protein	408
2919292123	148	63.64	4	146	28	132	1.4e-13	44.8	COG0835	Chemotaxis signal transduction protein	165
2919292124	121	50	4	121	2	117	1.2e-34	113.8	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2919292125	120	90.98	1	119	11	131	7.8e-29	94.5	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2919292126	57	94.55	4	57	2	53	2.3e-28	92.3	COG1773	Rubredoxin	55
2919292127	319	95.06	23	286	6	255	3.2e-35	115.6	COG0351	Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase	263
2919292128	436	97.69	3	436	9	430	0.0e+00	563.2	COG0001	Glutamate-1-semialdehyde aminotransferase	432
2919292129	259	97.56	13	259	3	242	2.6e-58	191	COG1414	DNA-binding transcriptional regulator, IclR family	246
2919292130	394	99.49	1	387	2	392	2.6e-75	248.3	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2919292131	159	76.36	42	143	21	104	5.7e-22	71.9	COG4654	Cytochrome c551/c552	110
2919292132	533	99.61	1	533	3	515	0.0e+00	736	COG0138	AICAR transformylase/IMP cyclohydrolase PurH	515
2919292133	77	76.53	1	77	23	97	1.1e-28	93.9	COG2901	DNA-binding protein Fis (factor for inversion stimulation)	98
2919292134	348	98.15	1	325	2	320	1.6e-109	360.1	COG0042	tRNA-dihydrouridine synthase	323
2919292136	160	96.89	1	157	2	157	2.3e-46	151.7	COG1238	Uncharacterized membrane protein YqaA, SNARE-associated domain	161
2919292137	413	96.17	205	391	7	182	8.6e-48	156.4	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2919292138	292	96.61	1	290	8	292	2.2e-105	346.3	COG2962	Uncharacterized membrane protein RarD, contains two EamA domains	293
2919292139	364	100	1	364	1	372	0.0e+00	495.3	COG0012	Ribosome-binding ATPase YchF, GTP1/OBG family	372
2919292140	290	95.19	10	286	3	259	5.3e-60	197	COG3217	Uncharacterized conserved protein YcbX, contains MOSC and Fe-S domains	270
2919292141	376	31.55	3	131	2	125	9.7e-73	61.2	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2919292141	376	60.56	125	376	154	391	9.7e-73	184.4	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2919292142	242	94.38	1	236	13	247	7.0e-22	72.3	COG1651	Protein-disulfide isomerase	244
2919292143	603	94.06	12	580	1	538	0.0e+00	543.3	COG3975	Predicted metalloprotease, contains C-terminal PDZ domain	558
2919292144	259	99.25	1	256	3	265	1.0e-86	284.7	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2919292147	448	99.32	1	441	2	439	0.0e+00	538.1	COG0621	tRNA A37 methylthiotransferase MiaB	437
2919292148	487	84.26	99	487	56	387	1.1e-55	184.2	COG0642	Signal transduction histidine kinase	336
2919292150	470	98.72	9	457	5	465	0.0e+00	532.5	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2919292151	504	91.21	1	504	38	525	0.0e+00	634.2	COG3131	Periplasmic glucans biosynthesis protein	534
2919292152	695	78.67	54	695	58	636	0.0e+00	699	COG2943	Membrane glycosyltransferase	736
2919292153	459	99.12	1	458	1	448	0.0e+00	601.8	COG0541	Signal recognition particle GTPase	451
2919292154	265	95.85	5	263	10	263	5.5e-48	158	COG4137	ABC-type uncharacterized transport system, permease component	265
2919292156	567	89.09	133	549	21	371	2.3e-45	150	COG0642	Signal transduction histidine kinase	336
2919292157	513	98.07	2	507	4	461	0.0e+00	509.1	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2919292158	209	68.97	14	207	6	185	1.6e-55	182.3	COG3023	N-acetyl-anhydromuramyl-L-alanine amidase AmpD	257
2919292159	979	6.68	73	147	23	73	0.0e+00	9.7	COG0209	Ribonucleotide reductase alpha subunit	696
2919292159	979	97.25	204	978	11	752	0.0e+00	605.7	COG0209	Ribonucleotide reductase alpha subunit	696
2919292160	398	96.49	55	398	10	339	2.2e-101	333.4	COG0208	Ribonucleotide reductase beta subunit, ferritin-like domain	348
2919292162	299	85.76	3	298	31	301	1.7e-47	156.1	COG0524	Sugar or nucleoside kinase, ribokinase family	311
2919292164	300	98.36	1	300	5	303	1.4e-70	232.3	COG2264	Ribosomal protein L11 methylase PrmA	300
2919292165	449	99.56	1	448	1	448	0.0e+00	681.5	COG0439	Biotin carboxylase	449
2919292166	150	98.64	6	150	2	146	2.1e-43	142.8	COG0511	Biotin carboxyl carrier protein	140
2919292167	119	30	1	107	36	80	3.8e-10	34.5	COG0526	Thiol-disulfide isomerase or thioredoxin	127
2919292169	473	98.26	1	473	8	460	0.0e+00	445.8	COG0773	UDP-N-acetylmuramate-alanine ligase	459
2919292171	373	99.15	18	372	3	350	0.0e+00	530.1	COG0722	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase	351
2919292173	494	98.9	33	493	5	455	0.0e+00	518.6	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
2919292174	112	83.05	56	110	10	58	2.5e-35	33.3	COG3422	Uncharacterized conserved protein YegP, UPF0339 family	59
2919292174	112	94.92	1	59	1	56	2.5e-35	81.3	COG3422	Uncharacterized conserved protein YegP, UPF0339 family	59
2919292175	391	96.07	9	386	10	376	3.4e-112	368.9	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
2919292176	812	76.81	25	407	2	362	3.4e-56	184.6	COG0515	Serine/threonine protein kinase	384
2919292177	194	97.42	2	194	3	191	5.3e-51	167.5	COG3150	Predicted esterase YcpF, UPF0227 family	191
2919292178	531	86.25	2	397	46	415	1.1e-09	32	COG3307	O-antigen ligase	424
2919292179	691	13.22	482	605	543	636	6.4e-60	45.6	COG0557	Exoribonuclease R	706
2919292179	691	43.88	92	488	168	479	6.4e-60	149.9	COG0557	Exoribonuclease R	706
2919292180	286	98.18	7	278	5	273	3.9e-20	66.9	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
2919292181	284	97.18	3	284	7	282	2.3e-81	267	COG0169	Shikimate 5-dehydrogenase	283
2919292182	244	31.7	1	243	30	255	7.9e-69	226.8	COG0744	Membrane carboxypeptidase (penicillin-binding protein)	661
2919292183	479	95.96	16	474	17	420	8.4e-86	282.5	COG2124	Cytochrome P450	411
2919292184	303	52.27	179	297	53	121	1.8e-05	18.2	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2919292185	337	88.4	54	335	22	280	2.0e-50	165.4	COG4242	Cyanophycinase and related exopeptidases	293
2919292186	253	73.18	2	251	36	226	1.3e-21	70.8	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
2919292187	330	99.01	12	329	3	302	3.8e-77	254.1	COG4589	Predicted CDP-diglyceride synthetase/phosphatidate cytidylyltransferase	303
2919292188	182	94.41	4	165	1	152	5.0e-56	183	COG0817	Holliday junction resolvasome RuvABC endonuclease subunit	160
2919292190	250	58.33	4	248	122	303	9.5e-30	98	COG0501	Zn-dependent protease with chaperone function	302
2919292192	342	92.42	17	334	20	336	2.0e-59	195.4	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2919292193	249	99.25	1	247	2	267	2.3e-75	247.7	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2919292194	410	99.75	1	410	1	397	3.2e-114	375.8	COG1459	Type II secretory pathway, component PulF	397
2919292199	745	99.16	143	719	4	590	0.0e+00	591	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
2919292200	735	87.74	165	481	39	317	1.4e-29	96.1	COG1181	D-alanine-D-alanine ligase and related ATP-grasp enzymes	317
2919292201	859	79.75	383	856	76	461	2.0e-55	182.3	COG0769	UDP-N-acetylmuramyl tripeptide synthase	475
2919292202	168	88.48	6	167	10	155	9.3e-62	201.4	COG3045	Periplasmic catabolite regulation protein CreA (function unknown)	165
2919292203	215	93.78	1	215	4	214	3.8e-65	214	COG2761	Predicted dithiol-disulfide isomerase, DsbA family	225
2919292204	266	98.88	3	262	2	266	6.2e-60	197.2	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2919292205	347	98.43	19	345	4	317	4.7e-88	289.4	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2919292206	300	96.22	9	298	10	289	9.3e-84	275	COG2513	2-Methylisocitrate lyase and related enzymes, PEP mutase family	289
2919292207	634	98.39	53	633	6	554	0.0e+00	480.3	COG3829	Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding Fis domains	560
2919292208	503	96.13	1	503	11	556	5.9e-113	372.3	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2919292209	388	98.98	1	387	4	393	6.4e-68	223.7	COG0183	Acetyl-CoA acetyltransferase	392
2919292210	324	21.53	3	43	105	135	7.0e-05	13.1	COG3793	Tellurite resistance protein	144
2919292210	324	22.92	49	118	105	137	7.0e-05	5.5	COG3793	Tellurite resistance protein	144
2919292210	324	92.09	157	303	4	131	4.4e-12	40.3	COG3597	Uncharacterized conserved protein, DUF697 family	139
2919292211	433	65.33	161	365	15	193	2.2e-04	15.2	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
2919292212	250	90.95	35	244	11	211	2.9e-15	50.6	COG2755	Lysophospholipase L1 or related esterase	216
2919292213	261	86.69	2	260	38	304	4.8e-12	38	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
2919292217	213	89.74	2	211	19	228	1.5e-51	168.7	COG1272	Predicted membrane channel-forming protein YqfA, hemolysin III family	226
2919292218	158	93.62	60	158	2	89	2.5e-06	22	COG0776	Bacterial nucleoid DNA-binding protein	94
2919292219	599	94.54	32	573	13	549	1.2e-59	196.1	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2919292220	321	81.76	3	309	2	270	1.6e-68	225.4	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
2919292221	331	96.55	6	329	10	317	8.5e-63	206.4	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2919292222	230	98.62	13	223	2	216	1.4e-22	74.3	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2919292223	276	92.88	8	272	21	294	1.5e-29	96.1	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2919292224	517	97.46	3	517	5	542	8.6e-129	424.3	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
2919292225	516	98.12	5	510	3	472	8.0e-70	229.6	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2919292227	313	78.26	27	99	5	58	2.9e-06	19.7	COG1476	DNA-binding transcriptional regulator, XRE-family HTH domain	68
2919292227	313	95.93	138	311	2	166	1.6e-35	116.3	COG0703	Shikimate kinase	172
2919292228	556	69.43	45	326	25	208	3.3e-33	94	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2919292228	556	74.34	305	535	32	228	3.3e-33	17.3	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2919292230	425	8.38	123	203	221	270	1.0e-49	1	COG0369	Sulfite reductase, alpha subunit (flavoprotein)	587
2919292230	425	39.03	187	425	365	597	1.0e-49	162.5	COG0369	Sulfite reductase, alpha subunit (flavoprotein)	587
2919292230	425	60.48	2	96	38	112	2.8e-13	43.3	COG1145	Ferredoxin	99
2919292233	222	51.85	40	209	125	264	9.7e-32	104.7	COG1360	Flagellar motor protein MotB	244
2919292236	300	96.68	6	299	2	292	3.1e-49	162.4	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919292237	524	71.64	2	503	35	476	1.3e-64	212.3	COG1009	NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit	606
2919292238	850	94.77	3	849	39	872	0.0e+00	656.9	COG3002	Uncharacterized conserved protein YbcC, UPF0753/DUF2309 family	880
2919292240	45	15.67	1	43	225	266	6.4e-09	30	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2919292241	439	42	11	220	26	214	3.0e-21	63.4	COG2271	Sugar phosphate permease	448
2919292241	439	42	224	425	251	439	3.0e-21	12.8	COG2271	Sugar phosphate permease	448
2919292242	101	32.56	5	101	1	98	9.8e-26	85.4	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919292244	235	98.51	1	233	4	267	4.1e-50	164.9	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2919292245	298	97.01	9	298	2	293	4.7e-56	184.9	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919292246	133	95.45	1	120	3	128	1.5e-19	64.6	COG0789	DNA-binding transcriptional regulator, MerR family	124
2919292247	242	72.2	5	228	81	293	6.6e-24	79.3	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2919292251	131	43.85	1	101	1	57	1.3e-10	36.2	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2919292252	435	23.74	248	295	11	43	1.4e-04	7.6	COG3415	Transposase	138
2919292252	435	28.78	198	255	4	43	1.4e-04	6	COG3415	Transposase	138
2919292254	346	96.35	3	293	6	295	2.0e-32	106.7	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2919292255	708	98.91	1	702	6	728	0.0e+00	746.3	COG2217	Cation transport ATPase	713
2919292256	144	94.7	1	125	1	125	7.5e-29	94.8	COG0789	DNA-binding transcriptional regulator, MerR family	124
2919292257	63	90.41	1	63	4	69	3.0e-11	37.9	COG2608	Copper chaperone CopZ	71
2919292259	113	93.52	2	111	7	107	4.1e-27	88.7	COG5569	Periplasmic Cu and Ag efflux protein CusF	108
2919292260	161	94.94	2	160	7	156	8.4e-48	156.6	COG4454	Uncharacterized copper-binding protein, cupredoxin-like subfamily	158
2919292261	470	23.55	205	337	363	476	8.1e-67	95.5	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
2919292261	470	35.12	4	218	1	170	8.1e-67	132.3	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
2919292262	477	89.57	19	462	36	447	3.3e-37	121.9	COG1538	Outer membrane protein TolC	457
2919292264	228	98.71	1	225	2	230	4.7e-83	272.2	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2919292265	439	82.23	56	432	66	389	2.5e-64	212.3	COG0642	Signal transduction histidine kinase	336
2919292267	102	76.42	2	102	26	106	1.1e-18	61.8	COG1677	Flagellar hook-basal body complex protein FliE	105
2919292268	174	47.56	110	165	37	75	6.8e-06	8.2	COG3423	Predicted transcriptional regulator, lambda repressor-like DNA-binding domain	82
2919292268	174	53.66	54	120	26	69	6.8e-06	9.9	COG3423	Predicted transcriptional regulator, lambda repressor-like DNA-binding domain	82
2919292271	673	87.55	6	673	88	727	0.0e+00	792.8	COG2217	Cation transport ATPase	713
2919292273	441	85.43	34	440	48	440	2.8e-18	59.9	COG1538	Outer membrane protein TolC	457
2919292274	505	16.15	74	166	34	96	7.1e-34	18.5	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2919292274	505	54.1	169	406	166	376	7.1e-34	102	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2919292274	505	71.3	408	502	30	106	1.6e-11	37.5	COG5569	Periplasmic Cu and Ag efflux protein CusF	108
2919292275	1049	99.81	1	1044	1	1028	0.0e+00	1425	COG3696	Cu/Ag efflux pump CusA	1027
2919292276	130	71.55	6	118	25	107	4.1e-25	82	COG3339	Uncharacterized membrane protein YkvA, DUF1232 family	116
2919292277	328	95.99	5	328	11	297	2.7e-88	290.3	COG1230	Co/Zn/Cd efflux system component	296
2919292278	90	98.88	1	89	1	88	9.9e-30	97	COG1937	DNA-binding transcriptional regulator, FrmR family	89
2919292279	1056	99.81	1	1045	1	1028	0.0e+00	1432.2	COG3696	Cu/Ag efflux pump CusA	1027
2919292280	113	100	1	113	1	112	2.8e-24	80	COG0347	Nitrogen regulatory protein PII	112
2919292281	507	86.41	153	503	36	372	1.5e-35	116.7	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2919292282	386	88.04	1	385	43	447	5.7e-55	181	COG1538	Outer membrane protein TolC	457
2919292285	228	99.14	1	227	1	230	5.5e-80	262.1	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2919292286	444	79.44	87	435	56	368	7.4e-51	167.9	COG0642	Signal transduction histidine kinase	336
2919292287	414	48.83	11	222	8	194	1.7e-31	58.2	COG0477	MFS family permease	338
2919292287	414	49.61	223	414	8	197	1.7e-31	52.1	COG0477	MFS family permease	338
2919292288	245	87.69	5	221	28	255	2.0e-39	129.6	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2919292289	222	87.72	115	220	12	111	7.4e-18	57.9	COG0607	Rhodanese-related sulfurtransferase	110
2919292296	75	28.86	17	75	106	148	1.0e-06	22.9	COG5642	Uncharacterized conserved protein, DUF2384 family	149
2919292299	109	86.81	3	92	11	89	5.8e-10	33.2	COG5606	Predicted DNA-binding protein, XRE-type HTH domain	91
2919292300	150	70.19	39	141	17	89	2.1e-07	24.5	COG2944	DNA-binding transcriptional regulator YiaG, XRE-type HTH domain	104
2919292301	103	95.74	1	93	2	91	1.1e-31	103.1	COG0776	Bacterial nucleoid DNA-binding protein	94
2919292302	257	81.05	2	254	34	264	5.0e-50	164.6	COG1864	DNA/RNA endonuclease G, NUC1	281
2919292304	232	77.43	1	227	28	202	1.2e-23	74.6	COG2135	Putative SOS response-associated peptidase YedK	226
2919292305	148	60.1	6	146	78	199	3.4e-30	99.3	COG1974	SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase)	201
2919292306	432	96.26	2	366	4	363	2.6e-52	172	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
2919292308	243	56.45	83	243	75	179	2.2e-07	24.2	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2919292310	1107	52.11	8	215	53	163	3.9e-09	27.9	COG2856	Zn-dependent peptidase ImmA, M78 family	213
2919292310	1107	93.89	196	845	3	632	1.9e-88	291.2	COG0210	Superfamily I DNA or RNA helicase	655
2919292313	171	70.37	14	147	22	116	5.0e-06	20.8	COG1310	Proteasome lid subunit RPN8/RPN11, contains Jab1/MPN domain metalloenzyme (JAMM) motif	134
2919292315	116	40.43	5	113	22	78	4.8e-03	10.7	COG1585	Membrane protein implicated in regulation of membrane protease activity	140
2919292317	643	100	1	643	1	615	0.0e+00	707.3	COG0449	Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains	597
2919292318	162	97.47	1	159	1	154	1.3e-29	97.4	COG1522	DNA-binding transcriptional regulator, Lrp family	154
2919292319	350	97.27	161	340	4	181	2.1e-51	168.2	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2919292320	260	31.47	4	260	508	743	8.3e-42	137.3	COG4251	Bacteriophytochrome (light-regulated signal transduction histidine kinase)	750
2919292321	472	98.69	2	472	3	455	0.0e+00	564.2	COG1207	Bifunctional protein GlmU, N-acetylglucosamine-1-phosphate-uridyltransferase/glucosamine-1-phosphate-acetyltransferase	460
2919292322	251	88.07	19	232	26	217	2.3e-29	96.6	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2919292324	421	99.52	1	421	2	413	0.0e+00	480.2	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
2919292325	208	91.87	1	201	9	200	3.3e-21	71	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2919292328	333	98.01	18	317	5	299	8.9e-62	203.6	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919292329	410	98.51	13	410	6	403	1.3e-122	403.8	COG0162	Tyrosyl-tRNA synthetase	401
2919292330	456	86.08	90	429	36	307	4.4e-58	191.6	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
2919292331	369	98.66	1	369	4	372	0.0e+00	432.6	COG2377	1,6-Anhydro-N-acetylmuramate kinase	371
2919292332	473	48.56	252	459	6	191	8.8e-37	6.9	COG0477	MFS family permease	338
2919292332	473	74.15	8	266	3	286	8.8e-37	118.8	COG0477	MFS family permease	338
2919292333	121	96.36	12	121	4	109	3.2e-44	143.6	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
2919292334	132	74.66	1	130	16	124	1.0e-30	100.7	COG1664	Cytoskeletal protein CcmA, bactofilin family	146
2919292336	130	93.98	2	130	9	133	1.3e-53	175	COG0103	Ribosomal protein S9	130
2919292337	143	95.95	2	143	2	143	1.4e-61	200.8	COG0102	Ribosomal protein L13	148
2919292338	656	64.04	13	347	3	303	1.8e-32	107	COG0515	Serine/threonine protein kinase	384
2919292339	295	97.85	2	294	2	274	3.9e-95	311.8	COG2961	23S rRNA A2030 N6-methylase RlmJ	279
2919292341	283	95.56	1	283	12	291	9.1e-85	278.5	COG0685	5,10-methylenetetrahydrofolate reductase	291
2919292342	333	40.82	220	333	143	242	4.2e-73	91.8	COG1189	Predicted rRNA methylase YqxC, contains S4 and FtsJ domains	245
2919292342	333	59.18	1	156	3	147	4.2e-73	146.2	COG1189	Predicted rRNA methylase YqxC, contains S4 and FtsJ domains	245
2919292343	477	99.52	9	469	3	419	0.0e+00	650.3	COG0499	S-adenosylhomocysteine hydrolase	420
2919292345	541	99.05	1	533	6	528	0.0e+00	742.8	COG4108	Peptide chain release factor RF-3	528
2919292347	115	35.88	1	115	187	294	6.6e-09	28.6	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2919292348	323	49.03	1	270	3	178	1.4e-13	45.8	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
2919292350	260	97.06	5	259	6	269	5.5e-20	64	COG0561	Hydroxymethylpyrimidine pyrophosphatase and other HAD family phosphatases	264
2919292351	413	97.42	97	404	1	302	5.0e-40	131.5	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
2919292352	150	98.61	1	147	1	142	1.3e-43	143	COG4154	L-fucose mutarotase/ribose pyranase, RbsD/FucU family	144
2919292353	268	49.3	6	266	4	250	2.1e-87	287.8	COG1129	ABC-type sugar transport system, ATPase component	500
2919292354	319	95.92	4	319	9	314	1.1e-91	301.2	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
2919292355	338	93.88	3	329	12	318	4.6e-69	226.8	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
2919292356	312	88.29	4	310	35	313	2.2e-40	132.7	COG0524	Sugar or nucleoside kinase, ribokinase family	311
2919292357	475	64.58	21	173	62	185	5.2e-17	56.2	COG1432	Uncharacterized conserved protein, LabA/DUF88 family	181
2919292358	320	95.92	3	318	13	318	1.6e-79	261.4	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2919292359	143	93.04	1	143	4	150	1.0e-29	97.8	COG1522	DNA-binding transcriptional regulator, Lrp family	154
2919292362	1957	21.47	1328	1566	402	603	0.0e+00	268.7	COG0178	Excinuclease UvrABC ATPase subunit	935
2919292362	1957	31.46	1010	1337	3	298	0.0e+00	264.4	COG0178	Excinuclease UvrABC ATPase subunit	935
2919292362	1957	35.92	1584	1957	603	940	0.0e+00	490.6	COG0178	Excinuclease UvrABC ATPase subunit	935
2919292362	1957	99.57	1	980	2	938	0.0e+00	1096.4	COG0178	Excinuclease UvrABC ATPase subunit	935
2919292363	372	95.63	15	371	3	352	2.2e-53	175.7	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2919292364	372	93.99	11	371	8	351	1.8e-45	149.6	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2919292366	553	19.06	391	548	114	186	8.8e-37	7.2	COG0477	MFS family permease	338
2919292366	553	98.69	16	336	2	379	8.8e-37	115.2	COG0477	MFS family permease	338
2919292367	217	95.07	1	195	8	200	2.0e-31	103.3	COG3917	2-hydroxychromene-2-carboxylate isomerase	203
2919292368	88	68.92	23	87	3	53	4.7e-19	62.5	COG3313	Predicted Fe-S protein YdhL, DUF1289 family	74
2919292369	177	90.32	13	165	15	154	2.2e-34	112.6	COG2606	Cys-tRNA(Pro) deacylase, prolyl-tRNA editing enzyme YbaK/EbsC	155
2919292370	447	96.92	25	413	9	386	1.2e-67	222.8	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2919292371	1062	99.8	1	1034	2	1013	0.0e+00	1142.5	COG0841	Multidrug efflux pump subunit AcrB	1009
2919292372	487	97.39	24	487	1	448	6.4e-114	375.4	COG1538	Outer membrane protein TolC	457
2919292373	302	68.04	5	301	2	282	2.4e-62	205.3	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
2919292374	305	97.01	6	303	6	297	5.4e-61	201.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919292375	327	89.06	8	314	6	298	2.6e-72	237.7	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
2919292376	285	97.65	15	285	4	294	1.3e-65	215.4	COG3246	Uncharacterized conserved protein, DUF849 family	298
2919292377	342	98.75	20	340	3	317	1.7e-89	294.1	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2919292378	306	83.44	29	306	51	322	2.5e-74	244.1	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
2919292379	672	99.69	1	670	1	644	0.0e+00	885.8	COG4770	Acetyl/propionyl-CoA carboxylase, alpha subunit	645
2919292381	261	98.87	1	259	4	265	8.9e-65	212.8	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2919292382	169	94.77	1	168	2	164	1.7e-36	119.9	COG2318	Uncharacterized damage-inducible protein DinB (forms a four-helix bundle)	172
2919292383	535	99.24	12	535	4	525	0.0e+00	676	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component	526
2919292384	576	97.18	19	575	10	561	0.0e+00	446.1	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2919292385	364	92.42	226	363	4	125	6.9e-22	70.9	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2919292386	228	94.42	1	216	9	211	1.6e-33	110.4	COG0625	Glutathione S-transferase	211
2919292387	217	97.74	2	217	1	216	1.2e-50	166.6	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
2919292388	119	77.48	1	119	13	129	5.3e-33	108.7	COG3012	Uncharacterized conserved protein YchJ, contains N- and C-terminal SEC-C domains	151
2919292390	159	65.62	5	158	4	150	2.0e-40	132.4	COG2323	Uncharacterized membrane protein YcaP, DUF421 family	224
2919292391	122	94.4	1	120	7	124	1.4e-55	181	COG3651	Uncharacterized conserved protein, DUF2237 family	125
2919292394	216	97.16	7	215	4	208	1.6e-40	133.1	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2919292395	851	72.59	343	699	103	388	5.4e-59	195	COG0642	Signal transduction histidine kinase	336
2919292397	376	96.99	1	376	6	392	0.0e+00	434.5	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2919292398	222	75	1	214	7	207	1.5e-26	87.7	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2919292400	395	99.49	4	395	2	393	8.6e-127	417.6	COG0183	Acetyl-CoA acetyltransferase	392
2919292401	601	98.27	6	600	6	573	0.0e+00	778.2	COG4579	Isocitrate dehydrogenase kinase/phosphatase	578
2919292402	219	97.12	2	204	3	204	4.1e-64	210.3	COG0288	Carbonic anhydrase	207
2919292403	396	97.99	9	395	3	393	6.7e-125	411.3	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2919292404	153	91.49	11	149	9	137	2.9e-31	102.2	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
2919292405	131	87.12	5	130	1	115	5.3e-27	88.8	COG0789	DNA-binding transcriptional regulator, MerR family	124
2919292406	357	86.92	17	345	13	238	4.4e-33	108.4	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2919292409	267	98.52	1	267	5	270	2.2e-111	365.4	COG1464	ABC-type metal ion transport system, periplasmic component/surface antigen	268
2919292410	768	69.08	266	766	182	639	1.4e-94	311.4	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2919292411	214	97.52	1	201	3	199	1.2e-65	214.8	COG1182	FMN-dependent NADH-azoreductase	202
2919292412	315	97.67	2	300	2	295	2.5e-72	238.3	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919292413	289	87.2	9	286	19	270	3.1e-40	131.8	COG1639	HD-like signal output (HDOD) domain, no enzymatic activity	289
2919292415	196	94.09	13	195	5	179	3.4e-41	135	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2919292417	194	96.69	3	178	2	176	9.4e-63	205.3	COG3545	Predicted esterase of the alpha/beta hydrolase fold	181
2919292418	334	91.98	1	334	27	347	0.0e+00	440	COG1613	ABC-type sulfate transport system, periplasmic component	348
2919292419	289	97.81	13	286	5	272	4.0e-112	367.6	COG0555	ABC-type sulfate transport system, permease component	274
2919292420	300	96.86	4	290	7	284	0.0e+00	468.1	COG4208	ABC-type sulfate transport system, permease component	287
2919292421	374	99.71	1	370	1	349	0.0e+00	460.3	COG1118	ABC-type sulfate/molybdate transport systems, ATPase component	345
2919292422	178	90.17	2	167	13	168	9.4e-30	97.8	COG1495	Disulfide bond formation protein DsbB	170
2919292424	222	94.42	5	207	3	205	1.3e-29	97.6	COG0625	Glutathione S-transferase	211
2919292425	333	97.4	5	313	5	304	6.1e-115	377.5	COG1054	Predicted sulfurtransferase	308
2919292426	542	24.72	143	291	125	211	5.1e-56	54	COG2206	HD-GYP domain, c-di-GMP phosphodiesterase class II (or its inactivated variant)	344
2919292426	542	31.82	395	537	207	318	5.1e-56	128.7	COG2206	HD-GYP domain, c-di-GMP phosphodiesterase class II (or its inactivated variant)	344
2919292427	302	98.01	3	289	2	296	1.0e-63	209.9	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919292428	294	86.23	9	292	40	327	5.3e-58	190.8	COG2367	Beta-lactamase class A	329
2919292429	448	94.12	302	448	2	145	5.1e-47	151.7	COG1246	N-acetylglutamate synthase or related acetyltransferase, GNAT family	153
2919292429	448	99.62	24	298	1	264	1.4e-65	215	COG0548	Acetylglutamate kinase	265
2919292432	1360	91.85	5	978	42	841	0.0e+00	868.6	COG1643	HrpA-like RNA helicase	845
2919292434	561	96.65	14	561	11	559	0.0e+00	434.3	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2919292436	986	66.37	479	985	207	646	6.0e-115	378.6	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2919292436	986	91.17	10	267	17	274	3.0e-33	108.3	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2919292438	259	87.17	24	247	24	220	3.4e-51	167.7	COG4340	Uncharacterized protein	226
2919292439	145	96.23	1	145	4	156	1.2e-35	117.8	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2919292440	333	97.49	9	331	6	316	7.9e-95	311.6	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2919292441	394	99.49	2	394	2	393	0.0e+00	459.8	COG0183	Acetyl-CoA acetyltransferase	392
2919292442	253	90.67	1	250	4	246	4.7e-36	118.9	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2919292443	171	91.73	32	167	10	131	6.4e-21	68.7	COG1846	DNA-binding transcriptional regulator, MarR family	126
2919292444	301	95.35	7	295	10	296	4.4e-40	131.8	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2919292445	220	71.23	2	220	81	288	1.0e-64	212.9	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
2919292446	746	63.74	617	746	9	124	4.2e-13	42.3	COG4567	Two-component response regulator, ActR/RegA family, consists of REC and Fis-type HTH domains	182
2919292446	746	66.24	233	580	129	389	1.1e-55	184.2	COG0642	Signal transduction histidine kinase	336
2919292447	218	92.59	11	218	14	213	5.7e-35	114.6	COG0778	Nitroreductase	207
2919292448	456	50.13	264	455	10	201	4.7e-12	7.9	COG0477	MFS family permease	338
2919292448	456	85.38	31	324	4	330	4.7e-12	35.6	COG0477	MFS family permease	338
2919292449	426	10.54	266	402	263	297	5.2e-06	1.7	COG3274	Surface polysaccharide O-acyltransferase, integral membrane enzyme	332
2919292449	426	39.16	14	186	4	133	5.2e-06	19.9	COG3274	Surface polysaccharide O-acyltransferase, integral membrane enzyme	332
2919292450	356	75.76	3	140	2	101	9.1e-27	87.4	COG0789	DNA-binding transcriptional regulator, MerR family	124
2919292451	122	55.34	2	121	92	205	1.4e-55	182.6	COG0545	FKBP-type peptidyl-prolyl cis-trans isomerase	205
2919292452	962	34	106	441	195	363	0.0e+00	29.7	COG1003	Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain	496
2919292452	962	94.97	455	934	25	496	0.0e+00	698.1	COG1003	Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain	496
2919292453	124	92.37	1	124	9	129	1.6e-46	151.5	COG0509	Glycine cleavage system H protein (lipoate-binding)	131
2919292454	380	98.96	3	380	2	382	7.1e-104	341.7	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
2919292457	425	99.21	45	423	1	376	0.0e+00	452.9	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
2919292458	164	87.01	1	164	5	158	1.5e-30	100.1	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
2919292459	323	98.8	1	323	3	330	8.5e-112	367.8	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
2919292460	141	86.08	1	140	17	152	2.2e-39	129.2	COG1522	DNA-binding transcriptional regulator, Lrp family	154
2919292461	303	98.67	1	296	1	297	3.9e-57	188.3	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919292462	274	95.47	9	270	11	263	1.0e-117	385.9	COG4336	Uncharacterized protein YcsI, UPF0317 family	265
2919292463	321	96.69	1	321	8	328	2.1e-59	195.6	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
2919292464	169	87.01	1	168	5	158	2.4e-18	60.3	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
2919292465	432	98.68	51	432	4	377	1.7e-97	320.4	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
2919292466	321	93.67	1	315	11	321	4.2e-53	174.8	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
2919292468	1214	92.39	688	1213	2	523	0.0e+00	663.1	COG0146	N-methylhydantoinase B/oxoprolinase/acetone carboxylase, alpha subunit	563
2919292468	1214	99.71	8	676	2	678	0.0e+00	783.4	COG0145	N-methylhydantoinase A/oxoprolinase/acetone carboxylase, beta subunit	674
2919292469	557	91.76	80	552	36	425	4.6e-106	349.6	COG0840	Methyl-accepting chemotaxis protein	408
2919292470	566	57.53	491	558	20	61	6.8e-04	12.9	COG1146	NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit	68
2919292470	566	100	15	476	1	407	9.1e-125	410.9	COG0644	Dehydrogenase (flavoprotein)	396
2919292471	260	99.25	5	259	2	267	2.3e-77	254.3	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2919292472	141	94.24	8	140	4	134	5.6e-28	91.7	COG0824	Acyl-CoA thioesterase FadM	137
2919292473	1053	66.97	574	1046	198	641	3.2e-105	346.2	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2919292475	193	91.4	2	178	17	186	1.5e-34	113.9	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
2919292476	281	28.46	188	264	175	244	1.5e-52	52.6	COG1414	DNA-binding transcriptional regulator, IclR family	246
2919292476	281	58.54	46	193	2	145	1.5e-52	120.4	COG1414	DNA-binding transcriptional regulator, IclR family	246
2919292477	335	97.49	11	333	6	316	4.7e-100	328.7	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2919292478	306	98.57	19	295	4	279	1.8e-45	149.8	COG3618	Predicted metal-dependent hydrolase, TIM-barrel fold	279
2919292479	335	96.55	12	334	10	317	1.2e-82	271.7	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2919292480	228	91.98	8	218	12	206	2.7e-59	194.3	COG0684	Regulator of RNase E activity RraA	210
2919292481	316	93.87	6	316	7	312	5.0e-87	285.8	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
2919292482	335	98.75	11	334	3	317	1.0e-80	265.3	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2919292483	317	97.18	1	315	6	315	2.4e-94	310.1	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2919292484	302	97.86	19	297	6	279	1.4e-46	153.4	COG3618	Predicted metal-dependent hydrolase, TIM-barrel fold	279
2919292485	305	91.26	32	304	25	306	8.3e-44	143.8	COG3386	Sugar lactone lactonase YvrE	307
2919292486	733	98.24	1	727	13	737	0.0e+00	1307.1	COG0376	Catalase (peroxidase I)	730
2919292487	131	93.55	10	128	3	118	2.8e-36	118.6	COG0599	Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family	124
2919292488	181	73.75	112	179	17	75	7.8e-17	54.2	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2919292489	235	98.64	1	221	2	218	4.0e-91	298.3	COG1788	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit	220
2919292490	212	91.56	1	211	6	211	3.3e-92	302	COG2057	Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit	225
2919292493	436	37.78	17	305	147	279	3.3e-26	86.5	COG2206	HD-GYP domain, c-di-GMP phosphodiesterase class II (or its inactivated variant)	344
2919292494	308	70.88	23	264	32	216	2.1e-20	66.9	COG4544	Uncharacterized conserved protein	260
2919292496	1090	91.88	27	1084	3	1065	0.0e+00	893	COG0587	DNA polymerase III, alpha subunit	1139
2919292498	305	97.34	3	297	4	296	1.8e-54	179.6	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919292499	278	79.32	53	271	20	207	6.2e-10	32.2	COG0412	Dienelactone hydrolase	236
2919292500	460	94.52	29	390	16	343	6.3e-111	364.6	COG2951	Membrane-bound lytic murein transglycosylase B	343
2919292501	481	98.32	1	478	8	474	0.0e+00	636.1	COG2925	Exonuclease I	475
2919292502	415	98.83	2	415	4	425	3.2e-125	412	COG2873	O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent	426
2919292503	442	66.81	12	334	2	315	2.1e-56	185.8	COG0515	Serine/threonine protein kinase	384
2919292504	409	26.21	236	310	9	62	1.1e-79	4.7	COG2715	Spore maturation protein SpmA (function unknown)	206
2919292504	409	99.03	1	215	1	204	1.1e-79	261.1	COG2715	Spore maturation protein SpmA (function unknown)	206
2919292505	237	93	2	236	13	238	1.5e-64	211.9	COG0217	Transcriptional and/or translational regulatory protein YebC/TACO1	241
2919292506	98	17.14	1	89	3	68	7.6e-25	82.2	COG0484	DnaJ-class molecular chaperone with C-terminal Zn finger domain	371
2919292510	408	93.99	206	384	10	181	2.7e-54	177.7	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2919292512	356	66.76	2	307	44	278	6.4e-40	130.8	COG1566	Multidrug resistance efflux pump	352
2919292513	914	50	702	908	65	207	1.9e-06	21.3	COG1277	ABC-type transport system involved in multi-copper enzyme maturation, permease component	278
2919292513	914	73.86	1	262	7	232	0.0e+00	216	COG1131	ABC-type multidrug transport system, ATPase component	293
2919292513	914	74.84	266	551	4	232	0.0e+00	275.8	COG1131	ABC-type multidrug transport system, ATPase component	293
2919292514	377	92.83	83	374	17	288	1.8e-29	96.5	COG0842	ABC-type multidrug transport system, permease component	286
2919292515	424	91.51	2	422	16	403	7.3e-83	272.4	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
2919292516	119	96.06	1	118	5	126	2.0e-33	109.6	COG3324	Predicted enzyme related to lactoylglutathione lyase	127
2919292517	307	96.71	2	306	10	303	4.8e-91	298.9	COG1079	ABC-type uncharacterized transport system, permease component	304
2919292518	353	97.21	1	353	3	350	1.3e-98	324.2	COG4603	ABC-type uncharacterized transport system, permease component	356
2919292519	543	16.17	458	540	421	501	0.0e+00	85.2	COG3845	ABC-type uncharacterized transport system, ATPase component	501
2919292519	543	83.23	2	424	3	419	0.0e+00	489.9	COG3845	ABC-type uncharacterized transport system, ATPase component	501
2919292522	323	97.05	48	322	4	233	1.8e-50	165.3	COG0775	Nucleoside phosphorylase	234
2919292523	336	98.02	2	335	4	349	3.9e-63	207.6	COG1744	Basic membrane lipoprotein Med, periplasmic binding protein (PBP1-ABC) superfamily	345
2919292524	209	100	1	209	1	210	1.3e-91	300.1	COG0035	Uracil phosphoribosyltransferase	210
2919292525	324	93.06	3	324	4	325	2.8e-116	382.6	COG1171	Threonine dehydratase	347
2919292526	280	96.98	2	267	8	264	3.6e-61	200.9	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2919292527	270	86.99	51	270	28	261	1.3e-44	146.8	COG4278	Uncharacterized protein	269
2919292528	512	84.92	16	501	3	458	1.0e-92	305.8	COG0433	Archaeal DNA helicase HerA or a related bacterial ATPase, contains HAS-barrel and ATPase domains	520
2919292529	239	98.35	1	239	2	240	4.0e-96	315.4	COG0217	Transcriptional and/or translational regulatory protein YebC/TACO1	241
2919292530	426	99.07	1	426	1	425	0.0e+00	588.2	COG0151	Phosphoribosylamine-glycine ligase	428
2919292531	323	98.68	7	315	5	303	0.0e+00	437.4	COG0408	Coproporphyrinogen III oxidase	303
2919292532	282	93.04	13	125	3	109	4.0e-35	112.9	COG0799	Ribosomal silencing factor RsfS, regulates association of 30S and 50S subunits	115
2919292533	155	100	1	154	1	156	1.4e-52	172.2	COG1576	23S rRNA pseudoU1915 N3-methylase RlmH	155
2919292534	204	95.88	1	204	5	190	2.0e-57	187.8	COG0424	Predicted house-cleaning NTP pyrophosphatase, Maf/HAM1 superfamily	193
2919292535	496	98.36	2	496	3	483	0.0e+00	553.2	COG1530	Ribonuclease G or E	487
2919292536	202	93.49	2	202	3	203	8.7e-46	150.7	COG0625	Glutathione S-transferase	211
2919292537	321	96.81	1	317	7	309	8.2e-59	193.7	COG2378	Predicted DNA-binding transcriptional regulator YafY, contains an HTH and WYL domains	311
2919292538	236	98.28	6	236	2	229	8.2e-78	255	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2919292539	908	98.66	1	899	3	887	0.0e+00	1025	COG2205	K+-sensing histidine kinase KdpD	890
2919292540	205	97.35	15	202	5	188	1.1e-79	260.7	COG2156	K+-transporting ATPase, c chain	190
2919292541	688	99.56	2	688	3	681	0.0e+00	1093.6	COG2216	High-affinity K+ transport system, ATPase chain B	681
2919292542	597	99.46	2	594	3	559	0.0e+00	797.1	COG2060	K+-transporting ATPase, A chain	560
2919292545	300	95.68	10	300	7	294	1.5e-36	120.4	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2919292546	388	96.46	12	388	9	390	2.7e-102	336.8	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
2919292547	313	99	1	301	1	298	5.9e-56	184.6	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919292548	123	46.61	1	121	2	118	1.7e-31	103.7	COG2138	Sirohydrochlorin ferrochelatase	245
2919292549	369	99.18	1	368	1	362	2.4e-74	244.8	COG0795	Lipopolysaccharide export LptBFGC system, permease protein LptF	364
2919292550	368	98.36	1	350	2	360	5.3e-58	190.9	COG0795	Lipopolysaccharide export LptBFGC system, permease protein LptF	364
2919292551	518	91.99	22	479	39	486	0.0e+00	519.8	COG0260	Leucyl aminopeptidase	485
2919292552	144	97.92	1	142	1	141	1.0e-26	87.9	COG2927	DNA polymerase III, chi subunit	144
2919292553	83	72.62	10	81	2	62	2.0e-04	15.4	COG5450	Transcription regulator of the Arc/MetJ class	84
2919292554	375	96.17	13	374	5	356	6.8e-69	226.6	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2919292555	335	93.56	3	335	16	320	5.4e-85	279.2	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
2919292558	224	98.52	4	222	3	202	6.1e-62	202.9	COG1974	SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase)	201
2919292559	317	87.15	1	316	26	337	1.2e-75	248.8	COG0252	L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D	351
2919292562	218	99.46	1	217	1	184	1.6e-72	237.7	COG0563	Adenylate kinase or related kinase	178
2919292563	279	97.17	10	279	3	242	2.2e-93	306	COG1212	CMP-2-keto-3-deoxyoctulosonic acid synthetase	247
2919292564	60	95.45	1	60	1	63	1.1e-25	83.6	COG2835	Uncharacterized conserved protein YbaR, Trm112 family	60
2919292565	322	82.74	1	304	26	303	1.2e-76	252	COG1663	Tetraacyldisaccharide-1-P 4'-kinase	336
2919292566	144	97.84	1	138	2	137	1.1e-32	107.2	COG0848	Biopolymer transport protein ExbD	137
2919292567	215	92.13	1	215	13	211	7.5e-46	150.7	COG0811	Biopolymer transport protein ExbB/TolQ	216
2919292568	441	97.98	9	440	5	440	1.6e-130	428.9	COG1570	Exonuclease VII, large subunit	440
2919292569	193	96.59	1	193	2	199	1.9e-73	240.9	COG0605	Superoxide dismutase	204
2919292570	179	88.1	55	179	8	118	4.2e-38	124.1	COG1430	Uncharacterized conserved membrane protein, UPF0127 family	126
2919292571	67	48.09	1	67	2	64	5.7e-03	10	COG5455	Periplasmic regulator RcnB of Ni and Co efflux	129
2919292572	419	99.75	10	419	1	407	0.0e+00	624	COG0538	Isocitrate dehydrogenase	407
2919292573	616	71.57	220	616	107	388	2.8e-71	235.4	COG0642	Signal transduction histidine kinase	336
2919292574	137	94.74	5	132	6	131	2.6e-35	115.3	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2919292575	1210	33.33	1	165	133	277	1.6e-43	68.5	COG3706	Two-component response regulator, PleD family, consists of two REC domains and a diguanylate cyclase (GGDEF) domain	435
2919292575	1210	37.24	769	936	264	425	1.6e-43	80.9	COG3706	Two-component response regulator, PleD family, consists of two REC domains and a diguanylate cyclase (GGDEF) domain	435
2919292575	1210	62.4	276	471	92	242	2.7e-31	41.5	COG2202	PAS domain	232
2919292575	1210	62.81	450	598	91	242	2.7e-31	75.3	COG2202	PAS domain	232
2919292575	1210	95.72	953	1208	3	248	4.5e-85	278.6	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
2919292576	294	99.65	1	292	1	285	4.6e-101	331.9	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
2919292577	133	95.73	1	127	4	115	4.9e-27	88.9	COG3189	Uncharacterized conserved protein YeaO, DUF488 family	117
2919292579	388	99	1	385	1	395	0.0e+00	448.5	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2919292580	128	84.38	2	121	16	123	7.8e-15	49	COG3755	Uncharacterized conserved protein YecT, DUF1311 family	127
2919292581	507	99.16	14	492	2	476	0.0e+00	480.7	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2919292582	351	96.55	25	350	10	317	4.1e-64	210.8	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2919292583	212	97.67	1	212	1	210	4.7e-50	164.6	COG0625	Glutathione S-transferase	211
2919292584	235	78.39	9	234	57	270	1.9e-60	198.7	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
2919292585	377	96.01	17	377	11	347	3.7e-112	368.8	COG3435	Gentisate 1,2-dioxygenase	351
2919292586	400	92.37	7	391	4	366	2.3e-66	219	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2919292587	160	92.48	11	142	5	127	3.6e-26	85.8	COG1846	DNA-binding transcriptional regulator, MarR family	126
2919292588	317	98.67	19	309	1	297	2.3e-52	172.7	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919292589	153	75.58	1	144	20	149	2.3e-16	54.4	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2919292590	150	43.26	3	101	16	76	1.3e-03	11.6	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
2919292591	190	15.56	18	185	102	136	1.2e-02	7.1	COG2979	Uncharacterized membrane protein YebE, DUF533 family	225
2919292592	559	83.25	5	559	61	388	2.0e-64	210	COG0642	Signal transduction histidine kinase	336
2919292593	52	13.83	1	25	9	21	5.9e-01	4.6	COG1826	Sec-independent protein translocase protein TatA	94
2919292593	52	18.09	30	51	5	21	5.9e-01	6.2	COG1826	Sec-independent protein translocase protein TatA	94
2919292594	547	75.72	42	322	4	293	8.0e-39	127.9	COG0477	MFS family permease	338
2919292595	441	96.59	3	373	6	345	7.2e-116	381	COG1566	Multidrug resistance efflux pump	352
2919292596	492	98.7	29	490	1	454	1.0e-111	368.2	COG1538	Outer membrane protein TolC	457
2919292597	177	88.72	28	163	15	132	4.9e-25	82.2	COG1846	DNA-binding transcriptional regulator, MarR family	126
2919292598	321	98.38	21	321	2	305	2.5e-77	254.3	COG1893	Ketopantoate reductase	307
2919292599	797	54.38	23	273	19	198	0.0e+00	23.2	COG0620	Methionine synthase II (cobalamin-independent)	330
2919292599	797	99.4	458	789	2	330	0.0e+00	444.8	COG0620	Methionine synthase II (cobalamin-independent)	330
2919292600	308	96.68	6	302	3	293	1.1e-58	193.4	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919292602	288	92.36	1	284	1	278	2.2e-41	136.6	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919292603	433	97.13	39	429	10	415	5.6e-49	161.2	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
2919292604	322	95.72	6	317	13	325	1.3e-96	317.2	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
2919292605	154	88.54	1	150	7	145	9.8e-05	15.1	COG4875	Uncharacterized protein	156
2919292606	303	97.32	7	303	4	294	5.0e-69	226.5	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
2919292607	323	98.12	3	322	5	317	1.4e-83	274.8	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2919292608	365	98.84	29	363	4	345	2.8e-79	260.9	COG2706	6-phosphogluconolactonase, cycloisomerase 2 family	346
2919292609	330	97.49	3	329	7	317	1.4e-90	297.8	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2919292611	684	61.03	90	480	95	296	8.0e-16	41.2	COG0790	TPR repeat	292
2919292613	615	98.31	22	607	10	591	0.0e+00	472.3	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
2919292614	155	90.06	1	155	10	154	8.2e-21	68.6	COG5615	Uncharacterized membrane protein	161
2919292616	449	97.27	263	443	5	182	2.3e-56	183.8	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2919292617	290	97.25	1	287	7	289	8.8e-84	275.2	COG2513	2-Methylisocitrate lyase and related enzymes, PEP mutase family	289
2919292618	402	99.47	6	397	2	377	0.0e+00	576.1	COG2828	2-Methylaconitate cis-trans-isomerase PrpF (2-methyl citrate pathway)	378
2919292619	878	98.39	3	866	14	869	0.0e+00	1098.1	COG1048	Aconitase A	861
2919292620	387	96.21	3	386	16	396	0.0e+00	449.3	COG0372	Citrate synthase	390
2919292621	132	77.71	1	131	9	130	3.4e-36	118.4	COG1607	Acyl-CoA hydrolase	157
2919292622	483	56.92	5	130	2	75	6.6e-15	49	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2919292622	483	99.1	146	477	3	331	0.0e+00	446.3	COG3800	Predicted transcriptional regulator	332
2919292623	1032	65.76	526	1029	212	647	6.2e-111	365.9	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2919292623	1032	92.61	1	329	22	347	6.3e-30	98	COG3614	Extracellular (periplasmic) sensor domain CHASE1 (specificity unknown)	348
2919292624	357	93.99	184	356	11	182	2.4e-46	151.6	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2919292625	1174	99.83	1	1172	2	1167	0.0e+00	807.1	COG1196	Chromosome segregation ATPase	1163
2919292627	695	99.41	14	691	4	673	0.0e+00	915	COG0272	NAD-dependent DNA ligase	667
2919292628	764	85.97	7	761	32	644	0.0e+00	524.7	COG0744	Membrane carboxypeptidase (penicillin-binding protein)	661
2919292629	77	68.57	22	74	6	53	6.3e-22	71.3	COG5515	Uncharacterized protein	70
2919292630	183	94.52	36	174	3	140	2.4e-21	70.2	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
2919292631	231	77.66	15	231	59	270	3.6e-74	243.8	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
2919292632	151	87.22	13	140	13	128	2.7e-21	70.1	COG1846	DNA-binding transcriptional regulator, MarR family	126
2919292633	222	97.67	1	221	1	210	2.0e-45	149.1	COG0625	Glutathione S-transferase	211
2919292634	301	39.44	181	301	151	249	5.9e-66	73.7	COG1496	Copper oxidase (laccase) domain	249
2919292634	301	56.97	13	179	3	145	5.9e-66	140.5	COG1496	Copper oxidase (laccase) domain	249
2919292636	566	99.56	109	564	3	452	0.0e+00	560	COG3243	Poly(3-hydroxyalkanoate) synthetase	445
2919292637	392	99.75	1	392	1	393	0.0e+00	476.6	COG0183	Acetyl-CoA acetyltransferase	392
2919292638	260	87.16	15	257	17	240	2.8e-54	177.8	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
2919292639	245	98.13	1	243	4	266	2.1e-71	234.7	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2919292640	679	98.88	1	535	3	531	0.0e+00	581.7	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
2919292641	309	93.73	13	301	14	282	1.4e-52	172.6	COG2890	Methylase of polypeptide chain release factors	280
2919292642	397	96.17	1	388	16	417	1.2e-103	341.6	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
2919292643	387	93.07	1	367	6	354	9.9e-129	423.1	COG5008	Tfp pilus assembly protein, ATPase PilU	375
2919292644	277	98.9	2	277	2	270	1.3e-94	310.9	COG2171	Tetrahydrodipicolinate N-succinyltransferase	271
2919292645	401	97.47	2	400	6	391	6.0e-99	325.8	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
2919292646	495	81.65	19	363	79	425	9.3e-93	305.8	COG0840	Methyl-accepting chemotaxis protein	408
2919292647	240	77.78	9	179	38	191	1.1e-51	169.3	COG2878	Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit	198
2919292648	523	98.31	1	426	1	408	0.0e+00	598.4	COG4553	Poly-beta-hydroxyalkanoate depolymerase	415
2919292649	362	75.76	3	233	37	211	3.7e-33	108.8	COG2357	ppGpp synthetase catalytic domain (RelA/SpoT-type nucleotidyltranferase)	231
2919292650	944	65.16	472	942	210	641	1.0e-113	374.5	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2919292650	944	96.31	28	379	11	349	3.8e-36	113.1	COG3614	Extracellular (periplasmic) sensor domain CHASE1 (specificity unknown)	348
2919292651	334	89.54	1	322	13	303	5.7e-92	302.5	COG0042	tRNA-dihydrouridine synthase	323
2919292653	195	62.84	8	194	31	194	1.2e-34	113.9	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
2919292654	149	95.57	1	148	2	152	2.3e-28	93.4	COG1522	DNA-binding transcriptional regulator, Lrp family	154
2919292655	373	97.16	13	373	3	379	9.4e-72	236.3	COG1748	Saccharopine dehydrogenase, NADP-dependent	389
2919292656	618	98.21	1	617	8	609	0.0e+00	492.1	COG1022	Long-chain acyl-CoA synthetase (AMP-forming)	613
2919292658	270	90.16	76	265	16	180	4.2e-48	157.2	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2919292659	211	90.09	1	211	10	218	5.4e-55	180.5	COG1802	DNA-binding transcriptional regulator, GntR family	230
2919292660	722	95.36	573	722	4	147	5.5e-58	187.7	COG2185	Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding)	143
2919292660	722	96.9	18	558	17	547	0.0e+00	807.1	COG1884	Methylmalonyl-CoA mutase, N-terminal domain/subunit	548
2919292661	321	93.5	1	314	20	321	3.3e-111	365.6	COG1703	Putative periplasmic protein kinase ArgK or related GTPase of G3E family	323
2919292662	510	97.72	1	510	13	526	0.0e+00	735.4	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component	526
2919292663	682	99.85	1	682	1	645	0.0e+00	866.4	COG4770	Acetyl/propionyl-CoA carboxylase, alpha subunit	645
2919292664	156	99.32	11	146	2	146	3.0e-05	18.5	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2919292666	129	30.33	3	129	165	282	2.8e-03	10.8	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
2919292667	347	92.01	17	345	13	323	1.1e-125	413.1	COG0502	Biotin synthase or related enzyme	335
2919292668	396	97.57	1	366	10	370	3.9e-130	428.2	COG3437	Response regulator c-di-GMP phosphodiesterase, RpfG family, contains REC and HD-GYP domains	360
2919292669	1028	48.71	660	806	2	114	2.9e-47	93.4	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2919292669	1028	52.59	513	656	2	123	2.9e-47	59.5	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2919292669	1028	71.2	820	971	21	109	3.3e-15	50.9	COG2198	HPt (histidine-containing phosphotransfer) domain	122
2919292669	1028	86.29	73	499	46	385	2.3e-79	260.5	COG0642	Signal transduction histidine kinase	336
2919292670	178	89.03	11	178	17	154	1.9e-41	135.8	COG3915	Uncharacterized protein	155
2919292671	121	79.03	5	115	18	115	2.9e-21	70	COG0599	Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family	124
2919292673	126	92.11	12	120	7	111	6.1e-24	78.2	COG0607	Rhodanese-related sulfurtransferase	110
2919292674	286	88.85	1	267	18	248	4.6e-45	148.3	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2919292675	111	70.34	12	107	16	98	5.1e-17	56.5	COG0640	DNA-binding transcriptional regulator, ArsR family	110
2919292676	143	68.72	3	143	17	161	8.1e-25	82	COG2391	Uncharacterized membrane protein YedE/YeeE, contains two sulfur transport domains	198
2919292677	149	64.45	7	145	24	159	1.8e-22	74.3	COG2391	Uncharacterized membrane protein YedE/YeeE, contains two sulfur transport domains	198
2919292678	118	83.08	3	117	2	109	4.3e-36	118	COG3453	Predicted phosphohydrolase, protein tyrosine phosphatase (PTP) superfamily, DUF442 family	130
2919292679	579	97.51	1	567	8	556	0.0e+00	432.9	COG0659	Sulfate permease or related transporter, MFS superfamily	554
2919292680	265	98.88	15	259	3	267	1.2e-74	245.3	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2919292681	473	95.87	7	457	11	451	6.3e-70	229.8	COG0534	Na+-driven multidrug efflux pump	455
2919292682	175	93.71	5	162	9	157	6.2e-33	107.3	COG2030	Acyl dehydratase	159
2919292683	420	96.46	8	413	5	385	8.0e-17	54.8	COG2814	Predicted arabinose efflux permease, MFS family	394
2919292684	159	86.47	20	150	2	116	4.6e-19	62.8	COG1846	DNA-binding transcriptional regulator, MarR family	126
2919292685	183	85.11	41	178	19	138	8.0e-34	110.3	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
2919292686	137	99.32	1	126	1	145	6.2e-27	89.8	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2919292687	173	70.35	27	172	57	196	3.4e-13	43.8	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
2919292688	197	91.05	19	197	9	181	2.4e-52	171.4	COG3703	Cation transport regulator ChaC	190
2919292689	174	93.99	3	172	11	182	3.1e-42	138.6	COG2032	Cu/Zn superoxide dismutase	179
2919292690	187	19	4	56	8	45	7.6e-31	17.1	COG2068	CTP:molybdopterin cytidylyltransferase MocA	199
2919292690	187	63	49	185	73	198	7.6e-31	88.5	COG2068	CTP:molybdopterin cytidylyltransferase MocA	199
2919292691	299	96.68	1	292	1	291	8.3e-55	180.7	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919292692	411	96.95	34	411	2	351	2.9e-97	319.7	COG1304	FMN-dependent dehydrogenase, includes L-lactate dehydrogenase and type II isopentenyl diphosphate isomerase	360
2919292694	79	16.98	8	74	163	207	4.4e-04	13.9	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2919292696	159	86.09	1	149	22	151	1.2e-40	133.3	COG3779	Uncharacterized conserved protein YegJ, DUF2314 family	151
2919292698	760	98.12	38	760	5	735	0.0e+00	464.5	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
2919292699	153	95.51	1	153	5	153	1.8e-63	207.1	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
2919292700	190	62.68	1	183	10	140	2.9e-21	71.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2919292701	213	99.07	1	213	3	214	2.0e-88	289.6	COG0259	Pyridoxine/pyridoxamine 5'-phosphate oxidase	214
2919292702	318	98.72	2	316	4	312	1.1e-45	150.1	COG0679	Predicted permease	311
2919292703	234	96.97	4	216	5	228	1.9e-13	42.4	COG1011	FMN phosphatase YigB, HAD superfamily	229
2919292704	364	97.45	9	363	6	349	6.6e-116	381.4	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
2919292705	465	74.37	23	452	80	372	1.5e-49	163.8	COG0642	Signal transduction histidine kinase	336
2919292706	241	99.14	1	221	1	230	4.2e-68	223.2	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2919292708	250	89.31	5	125	15	131	8.7e-30	97.1	COG2005	DNA-binding transcriptional regulator ModE (molybdenum-dependent)	130
2919292708	250	91.3	189	249	6	68	2.0e-15	14.6	COG3585	Molybdopterin-binding protein	69
2919292708	250	95.65	117	185	3	68	2.0e-15	34.4	COG3585	Molybdopterin-binding protein	69
2919292709	248	94.76	1	248	11	263	9.4e-44	143.8	COG0725	ABC-type molybdate transport system, periplasmic component	258
2919292710	227	97.33	3	226	3	221	9.0e-76	248.3	COG4149	ABC-type molybdate transport system, permease component	225
2919292711	362	99.15	6	362	2	350	6.6e-125	410.9	COG4148	ABC-type molybdate transport system, ATPase component	352
2919292712	540	86.89	294	539	18	176	2.5e-42	138.4	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2919292713	705	99.12	21	705	8	795	3.9e-71	233.7	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2919292715	209	45.18	53	194	64	138	1.6e-05	19.1	COG3495	Uncharacterized protein	166
2919292718	227	94.25	1	222	2	214	1.9e-49	162.2	COG1136	ABC-type lipoprotein export system, ATPase component	226
2919292719	141	86.21	1	137	17	141	1.5e-14	48.1	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
2919292720	180	90.23	1	172	5	161	6.5e-69	225.5	COG0225	Peptide methionine sulfoxide reductase MsrA	174
2919292721	287	94.16	1	286	9	282	4.1e-85	279.5	COG2513	2-Methylisocitrate lyase and related enzymes, PEP mutase family	289
2919292722	475	72.08	21	475	8	415	4.3e-38	123.3	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
2919292723	211	97.57	6	205	1	201	3.4e-38	125.6	COG1335	Nicotinamidase-related amidase	205
2919292724	694	99.41	14	689	2	676	0.0e+00	602.2	COG0145	N-methylhydantoinase A/oxoprolinase/acetone carboxylase, beta subunit	674
2919292725	570	96.46	14	568	2	546	0.0e+00	488.4	COG0146	N-methylhydantoinase B/oxoprolinase/acetone carboxylase, alpha subunit	563
2919292726	166	89.12	1	163	9	180	8.3e-36	117.7	COG0066	3-isopropylmalate dehydratase small subunit	191
2919292727	428	99.3	6	427	3	428	0.0e+00	439.5	COG0065	Homoaconitase/3-isopropylmalate dehydratase large subunit	423
2919292728	321	96.55	2	319	7	314	2.6e-84	277.1	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2919292729	238	99.16	4	238	2	236	4.3e-88	288.6	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2919292730	253	98.82	1	238	3	253	4.2e-87	285.1	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2919292731	323	95.05	1	312	11	317	6.7e-71	233.2	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2919292732	290	98.34	3	290	2	297	6.9e-72	236.6	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2919292733	400	95.08	7	393	7	354	1.1e-46	153.7	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2919292734	267	97.49	1	246	6	238	5.7e-51	166.9	COG2188	DNA-binding transcriptional regulator, GntR family	236
2919292735	252	93.3	10	223	6	200	3.3e-28	93.8	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2919292736	397	94.62	1	378	7	375	4.2e-35	115.7	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2919292737	1060	99.8	2	1039	2	1013	0.0e+00	1018	COG0841	Multidrug efflux pump subunit AcrB	1009
2919292738	237	89.1	18	233	3	190	7.8e-56	182.9	COG2518	Protein-L-isoaspartate O-methyltransferase	209
2919292739	113	81.58	2	113	19	111	7.6e-18	58.7	COG0607	Rhodanese-related sulfurtransferase	110
2919292740	444	92.61	3	442	33	458	2.2e-76	251.7	COG1538	Outer membrane protein TolC	457
2919292741	457	37.08	282	450	261	415	7.6e-110	149	COG1519	3-deoxy-D-manno-octulosonic-acid transferase	419
2919292741	457	62.2	4	274	2	261	7.6e-110	210.8	COG1519	3-deoxy-D-manno-octulosonic-acid transferase	419
2919292742	259	87.77	6	244	3	246	3.5e-34	112.2	COG0388	Predicted amidohydrolase	274
2919292743	462	96.23	2	453	11	470	1.2e-122	404.1	COG1109	Phosphomannomutase	464
2919292744	542	84.08	260	528	37	279	1.8e-52	172.3	COG0122	3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase	285
2919292744	542	95.77	10	215	5	185	4.8e-59	192.5	COG2169	Methylphosphotriester-DNA--protein-cysteine methyltransferase (N-terminal fragment of Ada), contains Zn-binding and two AraC-type DNA-binding domains	187
2919292745	183	97.02	7	169	5	167	5.6e-51	167.4	COG0350	O6-methylguanine-DNA--protein-cysteine methyltransferase	168
2919292746	308	93.36	10	296	13	293	4.4e-48	158	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2919292747	1272	42.15	43	286	99	200	7.0e-57	23.5	COG2202	PAS domain	232
2919292747	1272	45.87	564	685	102	212	7.0e-57	47	COG2202	PAS domain	232
2919292747	1272	53.31	247	409	49	177	7.0e-57	63.5	COG2202	PAS domain	232
2919292747	1272	58.68	406	574	100	241	7.0e-57	35.8	COG2202	PAS domain	232
2919292747	1272	62.9	796	1264	224	640	7.0e-108	355.1	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2919292747	1272	74.79	648	828	62	242	7.0e-57	45.2	COG2202	PAS domain	232
2919292748	148	65.43	3	143	48	153	7.1e-09	30.5	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2919292749	633	100	48	618	1	552	0.0e+00	654.6	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
2919292750	450	87.82	247	448	6	178	4.8e-75	43.6	COG2059	Chromate transport protein ChrA	195
2919292750	450	88.83	6	208	5	179	4.8e-75	210.3	COG2059	Chromate transport protein ChrA	195
2919292751	200	96.12	3	183	2	199	1.5e-16	48.3	COG1335	Nicotinamidase-related amidase	205
2919292752	303	83.65	6	300	20	285	5.9e-47	154.4	COG0462	Phosphoribosylpyrophosphate synthetase	314
2919292753	541	93.81	121	537	8	416	2.3e-112	369.6	COG0213	Thymidine phosphorylase	435
2919292754	390	88.86	9	389	46	412	2.7e-105	346.8	COG2133	Glucose/arabinose dehydrogenase, beta-propeller fold	399
2919292755	168	49.8	15	150	126	249	6.9e-47	154.8	COG0791	Cell wall-associated hydrolase, NlpC family	197
2919292757	235	70.08	6	217	35	205	1.8e-16	54.3	COG2114	Adenylate cyclase, class 3	227
2919292758	83	96.34	2	83	2	80	5.2e-17	56	COG2261	Uncharacterized membrane protein YeaQ/YmgE, transglycosylase-associated protein family	82
2919292759	171	69.06	20	151	2	97	2.5e-06	15	COG3597	Uncharacterized conserved protein, DUF697 family	139
2919292760	559	44.75	116	490	144	275	1.0e-04	12.5	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2919292761	345	97.81	17	344	6	317	8.8e-74	242.6	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2919292763	290	80	212	288	12	75	2.3e-14	46.3	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2919292764	936	77.41	400	892	32	408	2.4e-16	51.7	COG1061	Superfamily II DNA or RNA helicase	442
2919292765	390	96.3	26	217	6	187	7.5e-71	231.4	COG2169	Methylphosphotriester-DNA--protein-cysteine methyltransferase (N-terminal fragment of Ada), contains Zn-binding and two AraC-type DNA-binding domains	187
2919292765	390	97.02	216	378	4	166	4.9e-51	166.7	COG0350	O6-methylguanine-DNA--protein-cysteine methyltransferase	168
2919292766	254	97.03	14	254	7	235	5.9e-118	386.3	COG3826	Uncharacterized protein	236
2919292767	217	98.5	2	211	4	200	4.1e-59	194.1	COG3145	Alkylated DNA repair dioxygenase AlkB	194
2919292769	171	94.23	16	170	2	148	4.8e-58	189.5	COG2947	Predicted RNA-binding protein, contains PUA-like domain	156
2919292770	934	59.09	492	639	88	230	5.8e-42	53.5	COG2202	PAS domain	232
2919292770	934	72.31	580	769	56	230	5.8e-42	35.6	COG2202	PAS domain	232
2919292770	934	77.69	248	517	55	242	5.8e-42	66.8	COG2202	PAS domain	232
2919292770	934	92.35	753	930	5	173	1.6e-46	151.8	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2919292771	175	16.9	12	57	6	41	6.8e-14	13.5	COG0655	Multimeric flavodoxin WrbA	207
2919292771	175	30.99	53	133	75	140	6.8e-14	31.2	COG0655	Multimeric flavodoxin WrbA	207
2919292772	321	72.26	6	313	95	378	2.2e-54	178.7	COG1092	23S rRNA G2069 N7-methylase RlmK or C1962 C5-methylase RlmI	393
2919292773	365	71.38	9	349	91	322	5.5e-42	137.1	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
2919292774	790	48.4	5	367	8	384	5.3e-98	164.1	COG2366	Acyl-homoserine lactone (AHL) acylase PvdQ	768
2919292774	790	64.18	304	789	263	762	5.3e-98	173.9	COG2366	Acyl-homoserine lactone (AHL) acylase PvdQ	768
2919292775	210	86.05	37	205	10	157	1.2e-18	61.5	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
2919292776	253	99.21	1	252	1	252	5.1e-60	197.3	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
2919292777	301	97.01	3	300	2	293	2.4e-59	195.6	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919292778	316	97.34	5	312	4	296	1.4e-40	133.5	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2919292779	348	95.72	9	348	4	316	3.8e-46	151	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
2919292780	227	88.6	1	215	14	215	2.3e-65	214.5	COG0765	ABC-type amino acid transport system, permease component	222
2919292781	228	91.23	3	217	18	225	3.5e-70	230.2	COG0765	ABC-type amino acid transport system, permease component	222
2919292782	260	98.76	21	260	2	240	4.1e-103	337.8	COG1126	ABC-type polar amino acid transport system, ATPase component	240
2919292783	266	95.41	4	262	7	276	2.9e-58	191.4	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2919292784	180	79.45	7	157	5	120	1.1e-04	17.4	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2919292785	426	93.71	3	426	25	426	4.7e-104	342.1	COG1850	Ribulose 1,5-bisphosphate carboxylase, large subunit, or a RuBisCO-like protein	429
2919292786	451	98.31	6	450	2	409	4.2e-59	193.3	COG3395	Uncharacterized conserved protein YgbK, DUF1537 family	413
2919292787	473	98.87	4	465	3	440	8.9e-62	202.9	COG0527	Aspartokinase	447
2919292789	616	99.34	124	601	4	455	0.0e+00	506.7	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
2919292790	557	26.73	2	121	3	118	0.0e+00	101.8	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
2919292790	557	99.54	119	557	2	433	0.0e+00	480.7	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
2919292791	902	99.21	12	902	7	886	0.0e+00	1402.3	COG2609	Pyruvate dehydrogenase complex, dehydrogenase (E1) component	887
2919292792	853	66.5	448	839	129	390	2.5e-44	146.8	COG0642	Signal transduction histidine kinase	336
2919292793	208	96.53	4	205	4	198	4.0e-79	258.9	COG4566	Two-component response regulator, FixJ family, consists of REC and HTH domains	202
2919292794	284	98.94	4	284	1	281	1.2e-115	379.4	COG0190	5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase	283
2919292795	681	98.83	1	677	8	682	0.0e+00	825.9	COG0339	Zn-dependent oligopeptidase	683
2919292796	215	86.25	80	153	3	71	5.6e-07	23.6	COG0695	Glutaredoxin	80
2919292797	229	98.68	7	229	2	226	7.1e-81	264.9	COG0120	Ribose 5-phosphate isomerase	227
2919292798	351	92.26	40	351	5	290	4.3e-107	351.8	COG0167	Dihydroorotate dehydrogenase	310
2919292800	131	74.05	12	130	29	125	1.6e-07	25.4	COG5393	Uncharacterized membrane protein YqjE	131
2919292801	100	91.35	1	100	10	104	3.2e-19	63.9	COG4575	Membrane-anchored ribosome-binding protein, inhibits growth in stationary phase, ElaB/YqjD/DUF883 family	104
2919292802	365	85.81	3	365	3	371	5.5e-93	305.9	COG0579	L-2-hydroxyglutarate oxidase LhgO	429
2919292803	351	89.63	4	351	9	319	3.5e-94	309.7	COG0123	Acetoin utilization deacetylase AcuC or a related deacetylase	340
2919292806	237	92.13	1	234	18	251	6.9e-62	203.8	COG0847	DNA polymerase III, epsilon subunit or related 3'-5' exonuclease	243
2919292807	112	85.44	1	104	12	99	3.6e-26	85.3	COG0633	Ferredoxin	102
2919292808	623	99.5	10	609	4	606	0.0e+00	628.4	COG0443	Molecular chaperone DnaK (HSP70)	579
2919292809	172	94.83	5	171	1	165	8.5e-25	82	COG1076	DnaJ-domain-containing proteins 1	174
2919292810	107	98.18	1	107	3	110	4.6e-42	136.7	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
2919292811	133	95.36	1	131	5	148	3.2e-52	170.5	COG0822	NifU homolog involved in Fe-S cluster formation	150
2919292812	406	99.48	7	390	2	385	0.0e+00	529	COG1104	Cysteine sulfinate desulfinase/cysteine desulfurase or related enzyme	386
2919292813	178	95.33	1	149	1	143	1.3e-49	162.2	COG1959	DNA-binding transcriptional regulator, IscR family	150
2919292814	696	99.1	20	689	3	659	0.0e+00	1079	COG0556	Excinuclease UvrABC helicase subunit UvrB	663
2919292815	398	99.75	3	398	2	396	0.0e+00	553.7	COG1448	Aspartate/tyrosine/aromatic aminotransferase	396
2919292816	190	93.01	1	184	13	185	3.1e-53	174.1	COG3575	Uncharacterized protein	184
2919292817	287	95.91	16	287	8	265	6.5e-83	272.3	COG3384	Aromatic ring-opening dioxygenase, catalytic subunit, LigB family	268
2919292818	296	78.05	1	296	8	320	1.2e-52	173.2	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2919292819	236	84.04	143	233	9	87	1.0e-26	87.3	COG3326	Uncharacterized membrane protein YsdA, DUF1294 family	94
2919292819	236	94.03	2	67	2	64	3.2e-11	37	COG1278	Cold shock protein, CspA family	67
2919292821	803	99.8	53	728	1	497	0.0e+00	531.4	COG1032	Radical SAM superfamily enzyme YgiQ, UPF0313 family	490
2919292822	320	77.78	166	307	33	158	9.9e-10	31.9	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2919292822	320	98.5	20	153	2	132	1.8e-25	83.3	COG1846	DNA-binding transcriptional regulator, MarR family	126
2919292823	180	56.79	7	157	63	154	6.1e-10	33.7	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2919292825	197	95.05	1	194	5	196	6.4e-50	163.3	COG1739	Putative translation regulator, IMPACT (imprinted ancient) protein family	203
2919292826	471	99.12	1	444	4	454	1.7e-91	301.4	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
2919292828	381	94.85	1	371	3	370	4.0e-59	194.8	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2919292829	520	98.34	7	476	3	475	8.5e-119	391.5	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
2919292830	328	96.55	3	327	8	315	6.1e-88	289.1	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2919292831	454	96.16	2	447	17	442	0.0e+00	493.2	COG3048	D-serine dehydratase	443
2919292832	319	98.01	9	307	3	297	1.0e-57	190.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919292833	100	43.08	4	98	5	60	6.3e-12	40.8	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2919292835	235	97.84	5	235	4	229	1.4e-53	175.8	COG1814	Predicted Fe2+/Mn2+ transporter, VIT1/CCC1 family	229
2919292837	281	88.64	10	279	26	267	6.3e-86	282.4	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
2919292838	198	84.77	19	197	9	175	4.0e-32	105.5	COG2059	Chromate transport protein ChrA	195
2919292839	204	86.29	16	204	8	177	1.8e-27	90.1	COG2059	Chromate transport protein ChrA	195
2919292840	318	97.81	1	318	1	313	7.3e-102	334.7	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
2919292841	388	89.34	9	384	9	335	8.1e-35	114.6	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2919292842	241	96.89	1	241	2	250	1.0e-70	231.8	COG0846	NAD-dependent protein deacetylase, SIR2 family	250
2919292843	248	90.49	2	248	23	260	6.1e-80	262.4	COG0566	tRNA G18 (ribose-2'-O)-methylase SpoU	260
2919292844	233	97.37	11	233	3	224	2.4e-98	322.3	COG4181	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component	228
2919292845	226	96.38	27	226	5	217	1.1e-36	120.9	COG2755	Lysophospholipase L1 or related esterase	216
2919292847	289	88.93	13	287	26	282	2.5e-36	119.5	COG5473	Uncharacterized membrane protein	290
2919292848	408	98.99	1	406	4	396	9.8e-95	311.7	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
2919292849	163	34.01	8	86	6	72	2.4e-17	4.1	COG2823	Osmotically-inducible protein OsmY, contains BON domain	196
2919292849	163	50.76	50	162	96	195	2.4e-17	55.9	COG2823	Osmotically-inducible protein OsmY, contains BON domain	196
2919292850	562	95.03	4	550	3	537	6.8e-103	338.9	COG0659	Sulfate permease or related transporter, MFS superfamily	554
2919292851	257	40.23	21	219	258	432	1.2e-58	192.9	COG3706	Two-component response regulator, PleD family, consists of two REC domains and a diguanylate cyclase (GGDEF) domain	435
2919292852	263	91.73	7	263	2	245	2.2e-61	201.6	COG0455	MinD-like ATPase involved in chromosome partitioning or flagellar assembly	262
2919292853	258	77.27	4	256	4	241	5.8e-81	265.9	COG1054	Predicted sulfurtransferase	308
2919292854	297	93.57	7	279	16	277	3.4e-83	273.3	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
2919292855	135	94.16	1	135	7	135	3.0e-23	76.5	COG1765	Uncharacterized OsmC-related protein	137
2919292856	184	13.15	1	36	4	31	6.8e-27	13.1	COG0655	Multimeric flavodoxin WrbA	207
2919292856	184	67.61	35	184	69	212	6.8e-27	74.5	COG0655	Multimeric flavodoxin WrbA	207
2919292857	137	90.28	1	137	11	140	2.7e-36	119.3	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
2919292858	233	88.21	1	233	1	247	2.9e-61	201.6	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
2919292859	312	97.67	8	305	4	297	6.2e-49	161.4	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919292860	380	97.59	37	380	3	326	2.5e-72	238.1	COG3380	Predicted NAD/FAD-dependent oxidoreductase	331
2919292861	337	53.12	12	325	7	261	1.6e-79	261.5	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
2919292862	257	98.24	37	257	3	225	2.6e-74	243.7	COG0220	tRNA G46 methylase TrmB	227
2919292863	351	91.8	137	330	16	183	1.2e-43	142.6	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2919292864	993	31.82	839	983	206	317	8.6e-51	118.3	COG2206	HD-GYP domain, c-di-GMP phosphodiesterase class II (or its inactivated variant)	344
2919292864	993	34.09	489	688	92	211	8.6e-51	47.2	COG2206	HD-GYP domain, c-di-GMP phosphodiesterase class II (or its inactivated variant)	344
2919292865	875	99.43	1	874	5	881	0.0e+00	1133.3	COG0013	Alanyl-tRNA synthetase	879
2919292866	305	97.32	4	301	4	294	9.4e-82	268.1	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
2919292867	311	96.77	1	311	5	334	2.4e-102	336.6	COG3938	Proline racemase	341
2919292868	371	98.45	1	371	3	384	2.2e-66	218.9	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2919292869	98	7.46	6	91	5	77	5.3e-07	22	COG3383	Predicted molibdopterin-dependent oxidoreductase YjgC	978
2919292870	449	16.98	5	95	142	214	6.2e-31	44.5	COG0446	NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase	415
2919292870	449	69.3	97	432	102	399	6.2e-31	59.3	COG0446	NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase	415
2919292871	211	90.4	19	209	5	164	1.0e-25	78.9	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
2919292872	421	98.94	45	421	1	375	2.1e-123	405.9	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
2919292873	340	94.28	12	339	8	320	1.1e-77	255.6	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
2919292874	224	94.83	2	224	5	224	3.3e-41	135.4	COG1802	DNA-binding transcriptional regulator, GntR family	230
2919292875	472	96.93	9	468	3	444	2.9e-104	343.3	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
2919292876	434	95.96	2	430	18	445	0.0e+00	525.6	COG0160	4-aminobutyrate aminotransferase or related aminotransferase	447
2919292877	379	98.3	18	379	3	349	2.2e-126	416	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
2919292878	344	89.15	1	341	14	350	6.9e-69	226.8	COG0687	Spermidine/putrescine-binding periplasmic protein	363
2919292879	420	82.99	139	418	42	280	1.8e-86	283.7	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
2919292880	272	95.51	12	272	8	262	1.4e-86	284.1	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
2919292881	498	98.33	19	494	4	474	0.0e+00	588.7	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2919292884	302	94.18	19	298	14	288	6.3e-52	170.8	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
2919292885	674	95.57	1	649	30	676	1.6e-121	401.2	COG2982	Uncharacterized protein involved in outer membrane biogenesis	648
2919292886	782	40.75	421	752	470	797	0.0e+00	443.6	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
2919292886	782	50.43	1	427	3	408	0.0e+00	522.5	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
2919292887	119	86.92	14	118	14	106	7.4e-42	135.8	COG2127	ATP-dependent Clp protease adapter protein ClpS	107
2919292888	1177	94.21	1	1171	3	1092	0.0e+00	1312.5	COG0587	DNA polymerase III, alpha subunit	1139
2919292889	260	97.24	1	259	7	253	5.7e-76	249.4	COG4105	Outer membrane protein assembly factor BamD, BamD/ComL family	254
2919292890	690	95.58	15	678	13	660	1.4e-124	410	COG1199	Rad3-related DNA helicase	654
2919292891	67	79.1	7	65	11	63	8.7e-13	42.4	COG5481	Uncharacterized protein	67
2919292892	268	89.34	2	261	20	262	7.2e-34	111.3	COG0631	Serine/threonine protein phosphatase PrpC	262
2919292893	232	23.74	12	217	195	373	7.5e-02	5.8	COG0643	Chemotaxis protein histidine kinase CheA	716
2919292894	365	96.24	1	358	12	369	0.0e+00	452.2	COG1485	Predicted ATPase	367
2919292895	475	100	1	465	1	455	0.0e+00	538.1	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
2919292896	422	99.31	2	421	2	432	0.0e+00	475.7	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
2919292897	959	99.35	8	951	6	922	0.0e+00	1314.8	COG0567	2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes	906
2919292899	354	91.39	3	352	17	345	1.3e-68	225.6	COG0628	Predicted PurR-regulated permease PerM	355
2919292901	276	97.35	13	272	5	261	2.1e-81	267	COG1179	tRNA A37 threonylcarbamoyladenosine dehydratase	263
2919292902	249	92.8	1	249	17	261	3.8e-43	142.5	COG1729	Periplasmic TolA-binding protein (function unknown)	262
2919292903	180	88.44	3	180	21	196	6.1e-41	134.9	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
2919292904	439	97.2	22	437	12	428	1.4e-113	374.2	COG0823	Periplasmic component of the Tol biopolymer transport system	425
2919292905	600	98.48	20	593	4	586	0.0e+00	478.2	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
2919292906	224	48.18	7	121	76	234	1.0e-31	40	COG0666	Ankyrin repeat	235
2919292906	224	49.39	115	219	102	264	1.0e-31	66.3	COG0666	Ankyrin repeat	235
2919292907	268	98.83	1	265	2	255	5.9e-84	275.5	COG0084	Tat protein secretion system quality control protein TatD (DNase activity)	256
2919292908	119	99.15	1	119	2	117	4.3e-46	149.8	COG3215	Tfp pilus assembly protein PilZ	117
2919292910	225	95.19	3	211	3	200	3.4e-60	196.8	COG0125	Thymidylate kinase	208
2919292911	318	86.34	2	318	45	341	1.4e-101	334.1	COG1559	Cell division protein YceG, involved in septum cleavage	342
2919292912	305	87.99	6	301	17	287	6.9e-57	187.3	COG0354	Folate-binding Fe-S cluster repair protein YgfZ, possible role in tRNA modification	305
2919292913	285	82.58	158	285	24	151	4.2e-27	88.2	COG2153	Predicted N-acyltransferase, GNAT family	155
2919292913	285	96.4	3	140	4	137	4.0e-32	104.9	COG0824	Acyl-CoA thioesterase FadM	137
2919292914	320	95.28	4	318	15	317	7.7e-81	266.1	COG0657	Acetyl esterase/lipase	312
2919292915	289	92.05	6	288	14	256	6.6e-46	150.6	COG3971	2-keto-4-pentenoate hydratase	264
2919292916	378	99.74	1	378	1	378	1.3e-116	383.8	COG1454	Alcohol dehydrogenase, class IV	377
2919292917	940	59.5	10	359	99	242	1.3e-27	34.7	COG2202	PAS domain	232
2919292917	940	63.64	311	489	87	240	1.3e-27	68.6	COG2202	PAS domain	232
2919292917	940	66.67	440	939	214	655	4.1e-105	346.6	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2919292919	276	82.01	1	261	13	249	1.7e-40	132.7	COG1639	HD-like signal output (HDOD) domain, no enzymatic activity	289
2919292920	789	98.98	1	787	7	780	0.0e+00	986.9	COG2183	Transcriptional accessory protein Tex/SPT6	780
2919292923	379	66.77	14	270	14	234	5.6e-32	103.4	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2919292924	143	82.58	2	108	14	122	2.5e-22	73.5	COG0789	DNA-binding transcriptional regulator, MerR family	124
2919292925	133	84.68	8	130	18	122	6.5e-31	101.3	COG0599	Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family	124
2919292927	324	97.01	7	305	6	297	9.6e-69	226.4	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919292928	362	99.14	1	356	1	345	3.4e-125	411.7	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
2919292929	434	98.82	4	431	5	421	0.0e+00	510.6	COG2379	Glycerate-2-kinase	422
2919292930	344	98.12	23	343	5	317	2.2e-98	323.4	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2919292931	258	46.03	88	257	77	163	3.2e-16	53.2	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
2919292932	221	98.65	1	221	4	222	2.3e-93	305.9	COG2011	ABC-type methionine transport system, permease component	222
2919292933	348	99.41	1	346	1	338	0.0e+00	456.7	COG1135	ABC-type methionine transport system, ATPase component	339
2919292934	402	94.18	1	399	12	383	2.0e-33	109.5	COG2814	Predicted arabinose efflux permease, MFS family	394
2919292935	200	67.74	29	197	35	139	5.4e-12	40	COG3915	Uncharacterized protein	155
2919292936	411	94.43	19	411	12	384	8.3e-28	91.1	COG2814	Predicted arabinose efflux permease, MFS family	394
2919292937	314	97.34	13	308	3	295	3.4e-64	211.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919292940	309	98.01	10	309	3	297	1.8e-57	189.6	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919292941	338	97.49	18	337	7	317	7.4e-77	252.6	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2919292942	546	87.53	11	387	3	346	2.5e-52	171.1	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2919292943	164	89.39	18	147	12	129	7.2e-52	168.7	COG5649	Uncharacterized protein	132
2919292944	131	98.63	1	126	3	146	2.5e-11	38.8	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2919292945	311	89.14	4	307	24	302	1.3e-42	140.1	COG2017	Galactose mutarotase or related enzyme	308
2919292946	317	97.09	12	315	10	309	2.0e-72	238	COG3386	Sugar lactone lactonase YvrE	307
2919292947	273	99.25	25	273	2	267	4.4e-53	174.8	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2919292948	320	97.01	13	311	3	294	9.0e-59	193.7	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919292949	483	97.91	10	481	3	471	0.0e+00	523.2	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2919292950	321	93.88	1	320	2	308	7.2e-70	229.5	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
2919292951	356	98.53	3	356	4	339	0.0e+00	447.6	COG4213	ABC-type xylose transport system, periplasmic component	341
2919292952	505	98.4	1	504	8	500	0.0e+00	640.6	COG1129	ABC-type sugar transport system, ATPase component	500
2919292953	409	98.48	13	409	7	394	0.0e+00	507.9	COG4214	ABC-type xylose transport system, permease component	394
2919292954	517	98.4	11	515	4	496	0.0e+00	576.4	COG1129	ABC-type sugar transport system, ATPase component	500
2919292955	349	94.36	10	338	11	311	3.0e-77	253.6	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
2919292956	345	97.18	21	344	6	315	3.3e-84	276.5	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
2919292957	577	98.27	1	565	8	575	0.0e+00	614	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
2919292958	312	95.65	8	307	3	288	1.4e-51	169.1	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
2919292959	349	96.41	8	330	5	299	7.3e-72	235.8	COG3734	2-keto-3-deoxy-galactonokinase	306
2919292960	219	96.68	5	214	6	209	7.0e-57	186.2	COG0800	2-keto-3-deoxy-6-phosphogluconate aldolase	211
2919292961	382	98.39	1	366	4	370	8.5e-111	364.5	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
2919292962	561	57.58	6	367	12	273	1.7e-32	106.4	COG1479	Uncharacterized conserved protein, contains ParB-like and HNH nuclease domains	409
2919292964	766	80.53	92	766	111	656	3.7e-84	276.9	COG1199	Rad3-related DNA helicase	654
2919292965	504	98.61	1	500	1	497	0.0e+00	583.5	COG3333	TctA family transporter	504
2919292966	140	19.76	1	138	47	176	6.2e-02	5.9	COG1368	Phosphoglycerol transferase MdoB or a related enzyme of AlkP superfamily	650
2919292967	232	99.14	1	229	1	230	7.4e-64	209.3	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2919292968	494	85.53	109	486	56	392	6.4e-45	148.6	COG0642	Signal transduction histidine kinase	336
2919292969	247	54.23	75	186	13	89	8.3e-09	29.6	COG0727	Fe-S-cluster containining protein	132
2919292971	143	43.07	27	134	12	70	2.4e-04	14.7	COG4319	Ketosteroid isomerase homolog	137
2919292972	336	100	9	334	1	331	6.2e-81	266.5	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2919292973	291	98.34	1	284	1	296	1.1e-51	170.4	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919292974	318	96.68	17	317	2	292	1.6e-45	150.2	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919292975	546	91.94	57	516	37	458	4.7e-70	230.6	COG0165	Argininosuccinate lyase	459
2919292977	293	96.35	2	293	2	291	3.8e-44	145.8	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919292979	123	43.13	12	115	87	177	6.2e-05	16.7	COG1648	Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain)	210
2919292980	317	91.69	1	300	1	276	1.3e-57	190	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919292981	452	40.16	224	429	265	460	6.9e-91	131.7	COG3119	Arylsulfatase A or related enzyme	475
2919292981	452	41.8	10	217	4	207	6.9e-91	169.7	COG3119	Arylsulfatase A or related enzyme	475
2919292982	364	97.01	9	346	5	329	1.7e-47	156.2	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2919292983	277	96.41	4	254	4	245	5.2e-97	318.2	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2919292984	267	96.9	6	263	6	255	1.5e-73	241.3	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2919292985	290	96.9	32	289	6	255	4.3e-78	256.3	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2919292986	369	97.91	7	351	4	331	6.9e-42	137.3	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2919292987	285	95.47	10	285	4	277	4.0e-67	220.7	COG2175	Taurine dioxygenase, alpha-ketoglutarate-dependent	286
2919292988	454	100	15	426	1	343	9.6e-102	334.7	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2919292989	318	94.97	1	127	6	156	6.3e-14	9.5	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2919292989	318	95.6	130	275	5	156	6.3e-14	42	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2919292990	134	61.84	16	125	59	152	4.4e-24	79.2	COG0782	Transcription elongation factor, GreA/GreB family	151
2919292992	71	97.1	4	71	2	68	2.8e-30	98.7	COG3585	Molybdopterin-binding protein	69
2919292993	269	97.21	11	250	4	247	3.8e-85	279.4	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2919292994	294	96.12	37	293	10	257	2.9e-87	286.4	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2919292995	125	88.36	6	120	17	145	3.9e-06	21.3	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2919292996	387	98.25	6	362	1	337	2.6e-90	297	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
2919292998	325	91.64	5	319	9	315	2.4e-59	195.3	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2919292999	196	92.93	1	180	1	171	1.1e-38	126.9	COG0431	NAD(P)H-dependent FMN reductase	184
2919293000	340	89.97	6	340	33	346	0.0e+00	509	COG1613	ABC-type sulfate transport system, periplasmic component	348
2919293001	90	98.89	1	90	1	89	2.0e-43	140.6	COG2924	Fe-S cluster biosynthesis and repair protein YggX	90
2919293002	653	94.09	1	238	12	250	8.1e-61	198.4	COG4121	tRNA U34 5-methylaminomethyl-2-thiouridine-forming methyltransferase MnmC	252
2919293002	653	94.85	251	651	8	375	2.7e-36	120	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2919293003	267	94.98	1	267	8	253	1.7e-41	136.4	COG0730	Uncharacterized membrane protein YfcA	258
2919293004	594	99.81	1	581	1	513	0.0e+00	494.4	COG0155	Sulfite reductase, beta subunit (hemoprotein)	510
2919293005	130	64.67	2	130	56	163	2.6e-31	102.8	COG3749	Uncharacterized conserved protein, DUF934 family	167
2919293006	207	70.52	1	191	16	204	1.0e-29	97.7	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
2919293007	317	96.64	9	317	10	268	3.7e-68	223.8	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
2919293008	457	94.47	20	457	3	412	9.6e-127	413.3	COG2895	Sulfate adenylyltransferase subunit 1, EFTu-like GTPase family	431
2919293009	109	93.15	1	65	5	72	3.9e-18	59.4	COG1146	NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit	68
2919293010	355	97.39	11	331	4	302	1.5e-44	146.1	COG0492	Thioredoxin reductase	305
2919293012	426	85.04	7	422	16	396	2.6e-47	155.3	COG1457	Purine-cytosine permease or related protein	442
2919293013	287	97.72	13	278	4	260	2.2e-101	332.5	COG0351	Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase	263
2919293014	377	94.85	4	364	7	374	1.8e-49	162.9	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2919293015	65	97.06	1	65	3	68	9.2e-20	64.9	COG2104	Sulfur carrier protein ThiS (thiamine biosynthesis)	68
2919293016	269	98.09	4	265	5	261	1.4e-111	366	COG2022	Thiamin biosynthesis thiazole synthase ThiGH, ThiG subunit	262
2919293017	298	91	89	298	14	205	3.9e-57	186	COG0352	Thiamine monophosphate synthase	211
2919293019	507	32.83	382	499	158	265	1.0e-119	55	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
2919293019	507	86.32	3	337	4	287	1.0e-119	336.9	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
2919293020	259	97.36	1	258	7	264	8.1e-69	226.1	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2919293021	239	85.78	19	229	28	214	3.6e-29	96	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2919293022	361	99.39	12	353	2	326	1.2e-91	301.4	COG3173	Predicted  kinase, aminoglycoside phosphotransferase (APT) family	321
2919293023	424	99.25	1	412	1	396	3.5e-97	320.2	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2919293026	337	95.28	4	330	13	335	1.4e-91	301	COG4448	L-asparaginase II	339
2919293027	850	98.72	4	844	1	769	0.0e+00	538.6	COG2366	Acyl-homoserine lactone (AHL) acylase PvdQ	768
2919293028	309	72.95	3	180	56	233	3.8e-32	105.2	COG2114	Adenylate cyclase, class 3	227
2919293030	327	93.29	15	323	12	303	4.4e-72	236.7	COG1619	Muramoyltetrapeptide carboxypeptidase LdcA (peptidoglycan recycling)	313
2919293031	463	96.61	189	462	6	290	2.7e-30	100.4	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2919293031	463	96.73	1	149	5	152	2.9e-56	183.4	COG0590	tRNA(Arg) A34 adenosine deaminase TadA	152
2919293033	384	95.36	18	383	5	353	4.1e-65	214.2	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2919293034	667	87.71	3	348	4	310	4.5e-86	282.6	COG0826	Collagenase-like protease, PrtC family	347
2919293035	897	94.2	10	883	52	961	0.0e+00	863.8	COG0474	Magnesium-transporting ATPase (P-type)	917
2919293036	427	98.59	1	427	6	426	0.0e+00	645.1	COG2873	O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent	426
2919293037	401	27.03	315	401	243	332	1.4e-46	48.8	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
2919293037	401	36.94	88	325	81	203	1.4e-46	110.1	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
2919293038	305	93.81	2	305	20	322	6.8e-104	341.3	COG4301	Uncharacterized conserved protein, contains predicted SAM-dependent methyltransferase domain	321
2919293039	196	100	1	196	1	218	5.9e-55	180.4	COG3047	Outer membrane protein W	213
2919293040	329	10.56	1	34	1	32	2.8e-126	33.5	COG2354	Uncharacterized membrane protein MutK, may be involved in DNA repair	303
2919293040	329	95.38	31	324	14	302	2.8e-126	388.7	COG2354	Uncharacterized membrane protein MutK, may be involved in DNA repair	303
2919293041	307	98.34	6	304	1	296	3.0e-46	152.7	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919293042	327	80.58	3	91	14	96	4.0e-18	58.7	COG0633	Ferredoxin	102
2919293042	327	85.6	90	321	7	226	1.6e-57	188.2	COG0543	NAD(P)H-flavin reductase	252
2919293043	419	98.94	17	416	3	374	3.5e-82	270.7	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
2919293044	162	97.56	6	162	4	163	4.2e-38	125.2	COG5517	3-phenylpropionate/cinnamic acid dioxygenase, small subunit	164
2919293045	108	98.13	2	105	2	106	1.5e-28	93	COG2146	Ferredoxin subunit of nitrite reductase or a ring-hydroxylating dioxygenase	106
2919293046	1339	97.09	171	1014	8	742	0.0e+00	869.2	COG0046	Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain	743
2919293046	1339	99.18	1086	1339	2	243	7.4e-82	267.6	COG0047	Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain	231
2919293047	271	99.03	1	258	1	307	6.5e-88	289	COG0024	Methionine aminopeptidase	255
2919293048	866	97.69	2	866	16	862	0.0e+00	933.6	COG2844	UTP:GlnB (protein PII) uridylyltransferase	867
2919293049	179	91.12	1	168	1	154	7.9e-50	162.7	COG0242	Peptide deformylase	168
2919293052	251	94.57	12	238	6	214	9.9e-76	247.5	COG2360	Leu/Phe-tRNA-protein transferase	221
2919293053	252	96.44	3	251	5	248	3.5e-85	279.5	COG2935	Arginyl-tRNA--protein-N-Asp/Glu arginylyltransferase	253
2919293054	276	100	15	256	1	246	1.0e-72	238.1	COG1414	DNA-binding transcriptional regulator, IclR family	246
2919293055	358	65.9	40	357	33	291	3.5e-75	247.2	COG1686	D-alanyl-D-alanine carboxypeptidase	389
2919293056	512	99.52	3	416	2	412	0.0e+00	514.5	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
2919293057	277	97.89	15	260	3	234	1.8e-74	244.5	COG1183	Phosphatidylserine synthase	234
2919293058	338	99.11	1	336	3	337	0.0e+00	525.2	COG0059	Ketol-acid reductoisomerase	338
2919293059	163	97.53	1	161	3	160	3.5e-67	219.4	COG0440	Acetolactate synthase, small subunit	163
2919293060	597	99.28	27	594	3	553	0.0e+00	749.1	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
2919293061	189	90.32	2	189	14	181	2.0e-32	106.4	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2919293064	184	77.84	16	184	19	155	2.1e-10	34.5	COG1714	Uncharacterized membrane protein YckC, RDD family	172
2919293065	136	98.37	14	135	2	122	5.2e-44	143.1	COG0818	Diacylglycerol kinase	123
2919293066	197	84.88	3	188	18	191	2.6e-57	187.7	COG1611	Predicted Rossmann fold nucleotide-binding protein	205
2919293067	112	100	1	112	1	112	1.6e-49	161.3	COG0347	Nitrogen regulatory protein PII	112
2919293068	552	89.57	1	272	3	251	3.9e-54	177.4	COG0388	Predicted amidohydrolase	274
2919293068	552	94.89	266	541	7	266	7.1e-79	258.7	COG0171	NH3-dependent NAD+ synthetase	268
2919293069	420	97.93	2	420	8	386	0.0e+00	441.8	COG3146	Predicted N-acyltransferase	387
2919293070	721	87.29	44	511	55	425	2.4e-109	360.7	COG0840	Methyl-accepting chemotaxis protein	408
2919293071	54	34.82	2	53	38	76	9.3e-05	16.6	COG2158	Uncharacterized protein, contains a Zn-finger-like domain	112
2919293072	598	89.18	54	510	47	425	4.9e-112	369.3	COG0840	Methyl-accepting chemotaxis protein	408
2919293073	436	99.75	30	436	2	396	0.0e+00	509.5	COG0372	Citrate synthase	390
2919293074	108	82.98	10	101	11	88	8.9e-19	61.3	COG2938	Succinate dehydrogenase flavin-adding protein, antitoxin component of the CptAB toxin-antitoxin module	94
2919293075	234	97.45	2	234	3	231	2.5e-92	302.4	COG0479	Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit	234
2919293076	602	99.47	6	588	3	565	0.0e+00	736.6	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
2919293077	121	95.73	5	121	4	115	2.4e-32	105.4	COG2142	Succinate dehydrogenase, hydrophobic anchor subunit	117
2919293078	144	92.48	11	144	8	130	7.7e-19	61.9	COG2009	Succinate dehydrogenase/fumarate reductase, cytochrome b subunit	132
2919293079	262	95.82	21	261	8	236	1.9e-64	211.4	COG2188	DNA-binding transcriptional regulator, GntR family	236
2919293080	328	99.05	6	328	1	312	1.4e-81	268.2	COG0039	Malate/lactate dehydrogenase	313
2919293081	355	92.63	54	339	19	282	1.3e-50	165.9	COG2301	Citrate lyase beta subunit	283
2919293083	863	99.88	1	863	1	851	0.0e+00	1517.3	COG1049	Aconitase B	852
2919293084	851	14.55	777	849	66	113	8.8e-13	13	COG0666	Ankyrin repeat	235
2919293084	851	63.33	652	832	91	299	8.8e-13	36.6	COG0666	Ankyrin repeat	235
2919293085	329	78.52	1	327	76	393	0.0e+00	485.7	COG1133	ABC-type long-chain fatty acid transport system, fused permease and ATPase components	405
2919293086	181	97.8	1	181	5	182	5.9e-72	235.5	COG4567	Two-component response regulator, ActR/RegA family, consists of REC and Fis-type HTH domains	182
2919293087	443	80.71	31	440	72	389	4.3e-35	116.1	COG0642	Signal transduction histidine kinase	336
2919293088	272	96.85	5	261	4	249	1.4e-73	241.3	COG3346	Cytochrome oxidase assembly protein ShyY1	252
2919293089	143	95.54	4	126	5	111	3.8e-39	127.1	COG3125	Heme/copper-type cytochrome/quinol oxidase, subunit 4	111
2919293090	211	92.02	5	211	17	212	4.6e-71	232.6	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
2919293091	667	99.82	50	617	2	569	0.0e+00	749.4	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
2919293092	352	98.82	11	275	3	253	9.4e-79	258	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
2919293093	446	47.26	252	444	8	188	6.8e-27	31.6	COG0477	MFS family permease	338
2919293093	446	63.97	31	291	8	252	6.8e-27	59.8	COG0477	MFS family permease	338
2919293094	323	49.64	13	156	11	146	2.2e-13	8.9	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
2919293094	323	65.69	133	321	78	257	2.2e-13	40	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
2919293095	140	94.96	1	140	5	136	4.5e-37	121.4	COG0848	Biopolymer transport protein ExbD	137
2919293096	237	98.15	11	226	2	213	1.4e-70	231.9	COG0811	Biopolymer transport protein ExbB/TolQ	216
2919293097	147	94.96	6	147	3	134	1.1e-42	139.5	COG0824	Acyl-CoA thioesterase FadM	137
2919293098	394	98.74	5	394	2	392	3.7e-111	366	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
2919293099	179	94.12	22	167	7	150	2.4e-31	102.8	COG0781	Transcription termination factor NusB	151
2919293100	154	95.39	6	152	7	151	1.7e-53	174.6	COG0054	6,7-dimethyl-8-ribityllumazine synthase (Riboflavin synthase beta chain)	152
2919293101	373	87.24	211	373	2	172	8.4e-31	101	COG0807	GTP cyclohydrolase II	193
2919293101	373	98.03	8	211	4	202	1.2e-83	273.6	COG0108	3,4-dihydroxy-2-butanone 4-phosphate synthase	203
2919293102	98	84.47	7	97	8	94	1.6e-14	47.6	COG0633	Ferredoxin	102
2919293103	212	49.46	3	209	43	180	3.3e-06	21.8	COG0500	SAM-dependent methyltransferase	257
2919293104	93	72.73	1	93	28	123	2.2e-34	112.2	COG2343	Uncharacterized conserved protein, DUF427 family	132
2919293105	302	79.1	3	239	2	213	1.8e-55	182.7	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2919293106	508	97.3	1	502	14	517	0.0e+00	474.6	COG2918	Gamma-glutamylcysteine synthetase	518
2919293108	83	26.88	3	82	18	67	7.5e-06	19.5	COG3247	Uncharacterized membrane protein HdeD, DUF308 family	185
2919293109	323	92.05	1	303	12	312	8.6e-69	226.3	COG1161	Ribosome biogenesis GTPase A	322
2919293110	758	67.12	274	757	198	642	2.6e-104	344	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2919293112	429	96.2	20	416	14	393	1.8e-29	96.5	COG2814	Predicted arabinose efflux permease, MFS family	394
2919293115	311	66.06	5	276	44	261	3.3e-13	42.6	COG3608	Predicted deacylase	331
2919293116	320	97.34	31	316	4	296	2.0e-38	126.5	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2919293117	1217	59.5	95	405	99	242	2.5e-16	51.3	COG2202	PAS domain	232
2919293117	1217	69.8	389	692	115	389	6.3e-68	224.4	COG0642	Signal transduction histidine kinase	336
2919293117	1217	81.6	998	1154	7	108	9.4e-07	23.6	COG2198	HPt (histidine-containing phosphotransfer) domain	122
2919293117	1217	91.73	699	833	3	124	1.0e-53	59.8	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2919293117	1217	93.23	847	974	6	129	1.0e-53	122.8	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2919293118	233	61.96	62	209	21	121	1.1e-10	34.8	COG2062	Phosphohistidine phosphatase SixA	163
2919293119	392	96.22	2	384	15	370	3.0e-118	387.4	COG3437	Response regulator c-di-GMP phosphodiesterase, RpfG family, contains REC and HD-GYP domains	360
2919293120	316	96.81	4	310	4	337	7.6e-76	249.6	COG2070	NAD(P)H-dependent flavin oxidoreductase YrpB, nitropropane dioxygenase family	336
2919293121	263	70.89	1	221	82	288	2.3e-55	182.2	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
2919293122	111	17.88	7	99	66	124	6.1e-07	23	COG0666	Ankyrin repeat	235
2919293123	140	85.14	1	135	21	146	1.1e-27	91.1	COG4103	Uncharacterized conserved protein, tellurite resistance protein B (TerB) family	148
2919293125	408	94.98	1	403	7	403	2.2e-66	218.8	COG4102	Uncharacterized conserved protein, DUF1501 family	418
2919293126	534	78.83	78	531	88	478	8.1e-84	276.2	COG5267	Uncharacterized conserved protein, DUF1800 family	496
2919293127	432	67.89	21	294	8	267	5.2e-12	40	COG0477	MFS family permease	338
2919293128	145	72.68	2	145	46	186	4.7e-32	104.9	COG1525	Endonuclease YncB, thermonuclease family	192
2919293130	184	78.24	6	177	8	140	2.4e-19	63.8	COG0262	Dihydrofolate reductase	167
2919293131	296	96.68	15	295	5	295	3.7e-47	155.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919293132	202	98.6	1	200	1	212	1.7e-42	139.9	COG0625	Glutathione S-transferase	211
2919293133	236	97.21	10	217	1	209	1.7e-42	139.8	COG0625	Glutathione S-transferase	211
2919293134	178	67.07	1	178	65	229	3.0e-59	194.5	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
2919293135	308	56.01	33	308	127	303	1.2e-35	118.3	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
2919293136	432	84.33	24	429	64	472	1.9e-76	251.8	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
2919293138	261	84.45	3	261	3	241	3.8e-24	79.5	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2919293139	160	96.18	9	155	6	156	4.5e-24	79.4	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
2919293140	105	98.11	1	105	1	104	1.3e-33	109.7	COG4390	Uncharacterized protein	106
2919293141	109	54.74	34	101	17	68	1.4e-04	14.9	COG2827	Predicted endonuclease, GIY-YIG superfamily	95
2919293142	333	37.5	224	292	97	156	1.1e-01	6.8	COG4244	Uncharacterized membrane protein	160
2919293142	333	39.38	116	219	52	114	1.1e-01	5.4	COG4244	Uncharacterized membrane protein	160
2919293143	471	60.55	11	291	36	256	4.2e-26	85.9	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
2919293146	87	80.81	1	85	14	93	2.3e-05	19.2	COG3668	Plasmid stabilization system protein ParE	98
2919293147	77	11.06	2	74	51	103	9.2e-04	12.1	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2919293148	96	97.94	1	96	3	97	2.4e-23	76.5	COG1669	Predicted nucleotidyltransferase	97
2919293149	104	83.51	2	99	13	93	2.2e-17	57.3	COG1669	Predicted nucleotidyltransferase	97
2919293150	182	95.6	1	182	7	180	3.6e-61	200.6	COG3803	Uncharacterized conserved protein, DUF924 family	182
2919293152	611	98.54	53	588	8	480	5.7e-126	415.5	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
2919293154	157	97.95	5	155	2	144	4.1e-61	199.1	COG0757	3-dehydroquinate dehydratase	146
2919293155	137	52.72	4	136	106	231	4.6e-33	108.8	COG1186	Protein chain release factor B	239
2919293156	276	96.65	9	273	7	266	1.6e-76	251.3	COG3384	Aromatic ring-opening dioxygenase, catalytic subunit, LigB family	268
2919293157	223	96.17	3	218	6	206	4.1e-41	135	COG0400	Predicted esterase	207
2919293159	155	97.47	1	152	4	157	2.9e-43	141.9	COG1522	DNA-binding transcriptional regulator, Lrp family	154
2919293160	888	95.94	15	888	8	858	0.0e+00	1186.6	COG2609	Pyruvate dehydrogenase complex, dehydrogenase (E1) component	887
2919293162	274	86.09	5	273	20	248	4.0e-62	204.2	COG3228	Mlc titration factor MtfA, regulates ptsG expression	266
2919293163	258	90.46	20	247	2	219	3.3e-48	158.3	COG2908	UDP-2,3-diacylglucosamine pyrophosphatase LpxH	237
2919293164	175	94.27	13	175	5	152	6.5e-50	163.5	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
2919293165	175	98.73	14	175	2	156	3.2e-53	174.3	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
2919293166	430	63	124	373	42	230	6.2e-22	72.1	COG3034	Murein L,D-transpeptidase YafK	298
2919293167	368	89.78	250	367	5	127	5.4e-08	25.1	COG4319	Ketosteroid isomerase homolog	137
2919293168	460	99.35	2	459	2	463	0.0e+00	581.3	COG0215	Cysteinyl-tRNA synthetase	464
2919293169	224	73.01	15	220	67	277	1.4e-57	189.3	COG0122	3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase	285
2919293170	325	99.05	3	319	3	316	0.0e+00	493	COG0825	Acetyl-CoA carboxylase alpha subunit	317
2919293171	616	91.53	105	600	37	425	6.3e-114	375.3	COG0840	Methyl-accepting chemotaxis protein	408
2919293172	316	79.55	14	286	27	271	5.0e-55	180.8	COG0037	tRNA(Ile)-lysidine synthase TilS/MesJ	298
2919293174	142	93	1	100	7	99	1.3e-30	100	COG1188	Ribosomal 50S subunit-recycling heat shock protein, contains S4 domain	100
2919293175	486	85.03	119	475	56	390	1.4e-49	163.3	COG0642	Signal transduction histidine kinase	336
2919293176	227	99.57	1	227	1	231	1.1e-68	225.2	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2919293177	319	96.87	3	319	8	316	1.2e-88	291.6	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2919293179	501	97.82	1	501	1	493	0.0e+00	632.1	COG3333	TctA family transporter	504
2919293180	199	66.88	1	197	3	208	2.9e-24	80.1	COG0223	Methionyl-tRNA formyltransferase	307
2919293181	375	14.83	24	73	20	50	5.8e-09	9.9	COG4133	ABC-type transport system involved in cytochrome c biogenesis, ATPase component	209
2919293181	375	38.76	79	181	108	188	5.8e-09	18.3	COG4133	ABC-type transport system involved in cytochrome c biogenesis, ATPase component	209
2919293181	375	47.53	177	321	41	117	6.2e-05	16.7	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2919293188	1736	63.33	3	639	30	599	2.8e-50	165.7	COG5281	Phage-related minor tail protein	833
2919293194	178	28.06	1	47	1	39	5.5e-18	4.6	COG4387	Mu-like prophage protein gp36	139
2919293194	178	74.1	45	177	33	135	5.5e-18	53.3	COG4387	Mu-like prophage protein gp36	139
2919293196	297	97.4	1	295	9	308	4.1e-99	326.1	COG4397	Mu-like prophage major head subunit gpT	308
2919293198	403	94.96	18	398	15	353	5.7e-83	273.2	COG4388	Mu-like prophage I protein	357
2919293200	187	85.71	5	183	11	130	1.0e-20	68.3	COG5005	Mu-like prophage protein gpG	140
2919293203	538	94.58	11	527	26	514	0.0e+00	560.3	COG4383	Mu-like prophage protein gp29	517
2919293204	554	97.45	23	549	4	499	6.8e-115	378.6	COG4373	Mu-like prophage FluMu protein gp28	509
2919293205	197	19.55	10	193	159	289	1.8e-03	11.1	COG1269	Archaeal/vacuolar-type H+-ATPase subunit I/STV1	660
2919293208	77	62.5	2	77	41	115	3.7e-11	37.7	COG1734	RNA polymerase-binding transcription factor DksA	120
2919293210	205	59.41	4	192	121	300	1.1e-20	68.5	COG0741	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)	296
2919293211	119	35.92	7	119	100	201	1.5e-03	12	COG4025	Uncharacterized membrane protein	284
2919293214	142	45.38	2	107	2	60	2.9e-10	35.4	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2919293217	102	30.08	8	100	3	76	4.8e-08	26.5	COG1414	DNA-binding transcriptional regulator, IclR family	246
2919293219	597	33.1	119	335	134	227	1.4e-03	11.9	COG2801	Transposase InsO and inactivated derivatives	232
2919293220	413	95.62	106	409	12	273	6.7e-56	184	COG3267	Type II secretory pathway, component ExeA (predicted ATPase)	269
2919293226	90	95.74	1	90	2	91	1.1e-35	116.1	COG0776	Bacterial nucleoid DNA-binding protein	94
2919293227	219	60	11	158	2	103	1.2e-11	36.2	COG4382	Mu-like prophage protein gp16	170
2919293228	128	71.53	5	114	37	134	7.7e-13	42.7	COG5566	Transcriptional regulator, Middle operon regulator (Mor) family	137
2919293232	503	79.03	5	503	113	553	0.0e+00	447.8	COG3829	Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding Fis domains	560
2919293233	397	95.36	10	378	4	352	5.4e-37	121.4	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2919293234	494	26.2	192	374	36	117	2.7e-12	30.7	COG3509	Poly(3-hydroxybutyrate) depolymerase	312
2919293234	494	40.26	20	199	141	266	2.7e-12	20.9	COG3509	Poly(3-hydroxybutyrate) depolymerase	312
2919293235	260	97.64	1	251	6	253	1.4e-81	267.8	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2919293236	245	99.16	7	243	2	236	3.3e-81	266.2	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2919293237	328	97.34	28	328	4	296	3.8e-68	224.4	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2919293238	357	98.14	12	354	5	321	5.9e-71	233.5	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2919293240	388	94.54	11	386	8	353	1.1e-45	150.4	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2919293241	291	95.93	4	288	3	285	1.5e-30	101.1	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2919293243	80	86.25	3	80	2	70	1.1e-18	61.7	COG0695	Glutaredoxin	80
2919293244	188	96	9	184	6	173	3.8e-59	193.2	COG3040	Bacterial lipocalin	174
2919293245	344	97.89	8	344	4	328	8.3e-75	246.3	COG3380	Predicted NAD/FAD-dependent oxidoreductase	331
2919293246	523	99.14	1	474	2	460	1.2e-88	292.2	COG0415	Deoxyribodipyrimidine photolyase	461
2919293247	60	92.59	1	55	3	52	7.8e-26	84.4	COG4338	Uncharacterized protein	54
2919293248	438	89.42	1	436	1	414	3.6e-95	313.3	COG0415	Deoxyribodipyrimidine photolyase	461
2919293249	520	99.21	11	520	3	503	0.0e+00	643.1	COG3046	Uncharacterized protein related to deoxyribodipyrimidine photolyase	505
2919293250	245	69.03	16	240	29	213	2.9e-18	59.4	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2919293251	341	88.96	9	338	14	311	2.7e-37	122.4	COG2334	Ser/Thr protein kinase RdoA involved in Cpx stress response, MazF antagonist	331
2919293254	293	98.67	4	293	1	297	4.1e-60	198.4	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919293255	232	48.54	21	202	45	160	1.8e-20	67.2	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
2919293257	266	98.31	23	262	4	293	1.3e-26	80.9	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2919293258	295	95.45	1	294	11	304	1.2e-53	175.9	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
2919293261	828	69.1	300	806	174	609	1.7e-93	308.2	COG1067	Predicted ATP-dependent protease	647
2919293262	370	98.13	14	338	5	319	4.8e-113	371.6	COG0276	Protoheme ferro-lyase (ferrochelatase)	320
2919293263	223	92.11	2	219	15	224	1.2e-67	222	COG0765	ABC-type amino acid transport system, permease component	222
2919293264	217	92.11	1	214	17	226	1.5e-72	238.1	COG0765	ABC-type amino acid transport system, permease component	222
2919293265	268	95.41	4	268	7	276	3.9e-56	184.6	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
2919293266	259	99.17	13	253	2	241	4.4e-114	373.8	COG1126	ABC-type polar amino acid transport system, ATPase component	240
2919293267	248	80.22	21	247	22	244	2.5e-11	37.6	COG1082	Sugar phosphate isomerase/epimerase	274
2919293268	316	98.1	7	314	1	310	5.4e-71	233.3	COG0524	Sugar or nucleoside kinase, ribokinase family	311
2919293269	339	97.86	14	338	5	324	1.7e-90	297.4	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
2919293270	358	98.8	16	351	1	330	9.3e-84	275.7	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
2919293271	235	98.27	8	235	2	228	4.4e-38	125.7	COG1011	FMN phosphatase YigB, HAD superfamily	229
2919293272	287	88.58	3	270	27	282	1.3e-29	96.9	COG5473	Uncharacterized membrane protein	290
2919293275	349	98.75	18	346	4	318	4.8e-69	227.2	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2919293276	462	84.26	90	462	56	387	3.2e-52	172.9	COG0642	Signal transduction histidine kinase	336
2919293277	222	99.14	1	222	1	230	4.3e-68	223.4	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2919293278	336	96.55	14	334	9	316	1.4e-82	271.5	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2919293279	443	65.77	2	327	9	302	1.7e-30	98.8	COG2907	Predicted NAD/FAD-binding protein	447
2919293280	279	95.85	1	279	11	287	6.6e-88	289.1	COG1562	Phytoene/squalene synthetase	288
2919293281	503	97.76	1	468	8	444	3.7e-42	135	COG4664	TRAP-type mannitol/chloroaromatic compound transport system, large permease component	447
2919293282	177	81.87	11	175	16	164	1.2e-06	22.2	COG4665	TRAP-type mannitol/chloroaromatic compound transport system, small permease component	182
2919293283	469	26.18	4	85	52	123	2.8e-123	15.3	COG1760	L-serine deaminase	262
2919293283	469	99.64	180	465	2	275	2.8e-123	390.3	COG1760	L-serine deaminase	262
2919293284	302	91.35	28	302	20	283	1.4e-49	163.2	COG1562	Phytoene/squalene synthetase	288
2919293285	407	94.36	1	364	8	375	3.9e-51	168.8	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2919293286	1060	99.9	11	1049	1	1013	0.0e+00	927.5	COG0841	Multidrug efflux pump subunit AcrB	1009
2919293288	437	99.11	1	437	1	444	0.0e+00	444.4	COG0544	FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)	441
2919293289	202	95.5	6	202	3	193	9.1e-92	300.6	COG0740	ATP-dependent protease ClpP, protease subunit	200
2919293290	421	98.53	16	421	1	403	0.0e+00	673.7	COG1219	ATP-dependent protease Clp, ATPase subunit	408
2919293291	812	98.47	5	784	9	780	0.0e+00	1122.8	COG0466	ATP-dependent Lon protease, bacterial type	782
2919293297	174	73.57	1	163	55	221	6.4e-32	105.2	COG1451	Predicted metal-dependent hydrolase	223
2919293298	292	97.39	1	292	3	263	6.7e-69	224.7	COG0796	Glutamate racemase	269
2919293300	518	97.84	322	507	2	182	5.9e-72	234.8	COG1838	Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain	184
2919293300	518	97.99	2	309	3	295	2.0e-114	375.5	COG1951	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain	297
2919293301	469	99.13	9	469	3	460	0.0e+00	754.1	COG0114	Fumarate hydratase class II	462
2919293302	384	92.98	10	384	15	345	1.7e-95	314.3	COG3569	DNA topoisomerase IB	354
2919293303	232	98.71	3	230	2	230	4.8e-79	259.2	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2919293304	559	84.77	155	559	56	389	4.6e-57	188.1	COG0642	Signal transduction histidine kinase	336
2919293306	306	67.11	78	274	25	177	2.9e-29	96.7	COG3485	Protocatechuate 3,4-dioxygenase beta subunit	226
2919293307	199	95.86	5	199	8	169	4.0e-52	166.1	COG2862	Uncharacterized membrane protein YqhA	169
2919293308	664	99.82	78	650	1	551	0.0e+00	751.1	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
2919293310	101	85.45	1	101	12	105	9.6e-34	110.2	COG4654	Cytochrome c551/c552	110
2919293312	567	98.62	1	567	5	574	0.0e+00	706.1	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
2919293313	619	97.92	1	616	10	575	0.0e+00	792.3	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
2919293314	275	94.44	1	271	6	277	2.2e-93	306.5	COG0682	Prolipoprotein diacylglyceryltransferase	287
2919293315	305	96.68	13	305	7	297	1.1e-40	134.1	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2919293316	305	98.01	8	304	2	296	1.4e-68	226	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919293317	222	93.53	1	221	13	229	3.5e-59	194.4	COG1802	DNA-binding transcriptional regulator, GntR family	230
2919293319	329	97.81	9	327	5	316	4.3e-91	299.4	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2919293320	271	96.23	4	271	11	265	1.1e-53	176.2	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2919293321	517	97.36	1	516	8	560	5.9e-123	405.4	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2919293322	147	96.23	1	147	4	156	9.1e-33	108.6	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2919293323	837	98.77	69	796	6	727	0.0e+00	635.9	COG2217	Cation transport ATPase	713
2919293324	45	75.86	1	45	1	44	3.9e-17	56.3	COG3197	Uncharacterized protein, possibly involved in nitrogen fixation	58
2919293325	479	97.31	2	479	8	478	0.0e+00	809.3	COG3278	Cbb3-type cytochrome oxidase, subunit 1	482
2919293326	210	95.18	9	210	3	219	2.7e-97	315.9	COG2993	Cbb3-type cytochrome oxidase, cytochrome c subunit	227
2919293327	45	70	1	45	5	46	1.5e-12	42	COG4736	Cbb3-type cytochrome oxidase, subunit 3	60
2919293328	304	45.73	215	303	66	140	1.3e-38	36.3	COG2010	Cytochrome c, mono- and diheme variants	150
2919293328	304	83.54	77	221	7	143	1.3e-38	93.9	COG2010	Cytochrome c, mono- and diheme variants	150
2919293329	481	92.44	39	460	3	369	7.3e-114	374.8	COG0348	Polyferredoxin	386
2919293330	92	32.56	12	89	4	59	2.2e-12	41.2	COG3198	Uncharacterized protein	172
2919293331	98	18.81	1	81	108	180	1.9e-03	12.2	COG4763	Uncharacterized membrane protein YcfT	388
2919293332	240	98.17	8	227	3	216	4.2e-45	148.2	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2919293333	460	98.33	10	450	6	418	0.0e+00	432.8	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
2919293334	210	74.58	9	207	47	222	4.4e-19	63	COG2836	Sulfite exporter TauE/SafE	232
2919293335	434	71.59	90	370	100	351	1.1e-40	134.3	COG2206	HD-GYP domain, c-di-GMP phosphodiesterase class II (or its inactivated variant)	344
2919293336	814	41.32	7	115	125	224	1.5e-21	13.8	COG2202	PAS domain	232
2919293336	814	63.64	220	370	85	238	1.5e-21	39.4	COG2202	PAS domain	232
2919293336	814	63.65	340	808	224	645	1.2e-112	371.1	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2919293336	814	71.9	76	248	68	241	1.5e-21	34.6	COG2202	PAS domain	232
2919293337	271	98.84	1	271	1	256	5.2e-51	167.6	COG0730	Uncharacterized membrane protein YfcA	258
2919293338	125	64.76	1	123	1	68	2.9e-15	49.5	COG3027	Cell division protein ZapA, inhibits GTPase activity of FtsZ	105
2919293339	74	26.82	7	74	33	91	1.8e-04	15.8	COG3599	Cell division septum initiation DivIVA, interacts with FtsZ, MinD and other proteins	212
2919293341	627	97.88	21	626	12	611	0.0e+00	466.3	COG4206	Outer membrane cobalamin receptor protein	608
2919293342	460	98.9	12	457	2	449	2.7e-123	406.1	COG1797	Cobyrinic acid a,c-diamide synthase	451
2919293343	200	98.29	9	198	3	174	1.4e-48	159.1	COG2087	Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase	175
2919293344	343	95.68	9	301	11	320	6.9e-39	128.1	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
2919293345	341	97.31	9	338	7	332	2.0e-75	248.1	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
2919293346	264	93.8	4	260	3	244	9.6e-69	225.7	COG1120	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	258
2919293347	155	47.69	29	152	93	195	2.6e-14	48.2	COG0811	Biopolymer transport protein ExbB/TolQ	216
2919293348	128	84.3	5	111	16	117	3.1e-26	85.7	COG4744	Uncharacterized protein	121
2919293349	1391	91.76	50	1380	116	1418	0.0e+00	789.2	COG1429	Cobalamin biosynthesis protein CobN, Mg-chelatase	1388
2919293350	189	90.91	1	188	18	197	2.4e-65	214.2	COG2109	ATP:corrinoid adenosyltransferase	198
2919293351	334	96.25	18	329	9	316	2.0e-84	277.4	COG1270	Cobalamin biosynthesis protein CobD/CbiB	320
2919293352	359	94.46	7	346	18	358	4.3e-33	106.6	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
2919293355	497	90.74	10	470	3	443	0.0e+00	492.9	COG1492	Cobyric acid synthase	486
2919293356	260	65.23	9	250	23	204	6.8e-16	53.2	COG0500	SAM-dependent methyltransferase	257
2919293357	354	93.14	9	354	14	339	3.7e-80	263.6	COG2038	NaMN:DMB phosphoribosyltransferase	347
2919293358	377	94.54	204	377	10	182	1.4e-50	165.7	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2919293359	353	98.58	9	347	4	351	3.7e-112	365.2	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
2919293360	437	96.03	23	437	11	373	3.2e-33	108.6	COG0687	Spermidine/putrescine-binding periplasmic protein	363
2919293361	304	91.32	11	303	11	273	1.0e-73	242.3	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
2919293362	295	95.51	2	293	6	260	1.1e-57	189.5	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
2919293363	254	91.81	14	246	13	225	1.8e-61	201.7	COG1802	DNA-binding transcriptional regulator, GntR family	230
2919293364	248	91.74	2	220	2	212	8.6e-44	143.7	COG4126	Asp/Glu/hydantoin racemase	230
2919293365	74	51.22	2	73	3	44	1.2e-06	22.9	COG2336	Antitoxin component of the MazEF toxin-antitoxin module	82
2919293366	130	90.15	5	130	9	127	1.5e-32	106.4	COG3654	Prophage maintenance system killer protein	132
2919293367	213	98.1	2	212	2	208	4.6e-83	271.8	COG0177	Endonuclease III	211
2919293368	321	97.67	9	305	5	298	2.1e-59	195.9	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919293369	490	99.17	13	487	3	479	4.7e-122	402.6	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
2919293370	325	98.12	2	323	4	316	1.0e-88	291.7	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2919293371	159	73.38	1	147	1	113	1.6e-24	80.4	COG3449	DNA gyrase inhibitor GyrI	154
2919293372	396	84.21	2	396	67	450	2.2e-118	390.2	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
2919293373	75	90.28	6	75	8	72	9.8e-12	39.2	COG2900	Uncharacterized coiled-coil protein SlyX (sensitive to lysis X)	72
2919293374	214	92.82	8	214	9	202	1.9e-24	81.8	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2919293375	702	99.17	23	382	3	362	7.2e-100	328.6	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
2919293376	219	43.09	50	217	3	158	1.3e-10	35.1	COG0349	Ribonuclease D	361
2919293377	509	90.85	1	471	3	409	1.1e-46	153.7	COG3025	Inorganic triphosphatase YgiF, contains CYTH and CHAD domains	432
2919293378	345	86.46	3	314	44	324	3.2e-66	217.9	COG0226	ABC-type phosphate transport system, periplasmic component	318
2919293379	549	81.88	27	509	78	425	5.6e-96	316.6	COG0840	Methyl-accepting chemotaxis protein	408
2919293381	420	40.08	5	113	128	224	1.6e-24	16.5	COG2202	PAS domain	232
2919293381	420	58.26	98	246	102	242	1.6e-24	63.1	COG2202	PAS domain	232
2919293381	420	97.27	233	414	4	181	4.4e-54	176.9	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2919293383	426	80.38	1	425	29	446	0.0e+00	454.9	COG0513	Superfamily II DNA and RNA helicase	513
2919293384	156	18.8	1	149	45	116	6.7e-02	5.1	COG0477	MFS family permease	338
2919293385	120	93.33	10	120	6	103	1.3e-28	93.4	COG0023	Translation initiation factor 1 (eIF-1/SUI1)	104
2919293386	70	97.18	1	70	1	69	1.5e-32	105.9	COG3530	Uncharacterized conserved protein, DUF3820 family	71
2919293387	374	97.21	6	357	5	318	1.8e-90	297.7	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2919293388	193	46.03	25	158	77	163	2.2e-08	28.5	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
2919293389	297	97.67	2	297	3	296	3.4e-76	251.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919293391	158	79.7	4	131	16	121	4.2e-20	66.4	COG2346	Truncated hemoglobin YjbI	133
2919293392	249	97.74	19	235	4	219	8.0e-88	288	COG2846	Iron-sulfur cluster repair protein YtfE, RIC family, contains ScdAN and hemerythrin domains	221
2919293393	172	90.67	1	150	1	136	1.2e-41	136.5	COG1959	DNA-binding transcriptional regulator, IscR family	150
2919293394	237	96.7	22	237	6	210	1.5e-68	224.6	COG0560	Phosphoserine phosphatase	212
2919293396	265	98.39	5	257	4	308	8.7e-90	295.2	COG0024	Methionine aminopeptidase	255
2919293398	220	78.03	3	219	44	217	7.4e-15	49	COG3235	Uncharacterized membrane protein	223
2919293399	1154	98.86	1	1152	10	1136	0.0e+00	1432.2	COG1197	Transcription-repair coupling factor (superfamily II helicase)	1139
2919293400	304	7.33	15	65	4	20	4.8e-55	3.5	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	230
2919293400	304	90.52	47	281	20	229	4.8e-55	175.9	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	230
2919293401	159	98.11	3	159	1	156	6.1e-60	196.2	COG0245	2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	159
2919293402	345	98.5	20	345	1	329	6.5e-89	292.7	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
2919293403	303	97.32	7	303	4	294	1.6e-68	225	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
2919293404	329	96.87	4	328	8	316	2.1e-91	300.6	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2919293405	450	98.66	13	420	3	370	9.1e-83	272.3	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
2919293406	509	81.98	13	482	64	386	4.5e-47	153.4	COG0642	Signal transduction histidine kinase	336
2919293407	243	98.71	9	241	2	230	2.0e-85	280.1	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2919293408	237	98.3	1	236	5	235	5.6e-44	144.6	COG3471	Predicted secreted (periplasmic) protein	235
2919293409	260	99.25	1	259	2	267	1.7e-68	225.4	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2919293410	322	96.61	22	317	9	293	2.1e-27	90.8	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2919293411	737	98.48	11	737	11	723	0.0e+00	732.6	COG0317	(p)ppGpp synthase/hydrolase, HD superfamily	701
2919293413	157	56.69	1	156	118	278	7.3e-35	114.9	COG2801	Transposase InsO and inactivated derivatives	232
2919293417	342	93.98	43	342	2	251	1.2e-34	114	COG1801	Uncharacterized conserved protein YecE, DUF72 family	263
2919293418	341	97.27	153	338	4	181	5.9e-55	179.5	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2919293419	201	97.62	16	188	5	168	3.8e-32	106.2	COG0350	O6-methylguanine-DNA--protein-cysteine methyltransferase	168
2919293420	301	83.58	3	267	2	225	1.1e-44	147.2	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2919293421	313	95.35	4	235	1	205	2.6e-25	83.4	COG0625	Glutathione S-transferase	211
2919293422	555	92.73	45	459	25	394	7.9e-71	233	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2919293423	150	98.06	1	150	1	152	1.1e-51	169.1	COG2153	Predicted N-acyltransferase, GNAT family	155
2919293424	338	97.35	1	338	8	338	2.7e-129	425.1	COG2130	NADPH-dependent curcumin reductase CurA	340
2919293425	143	87.23	2	128	17	139	3.4e-33	108.5	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
2919293426	263	98.88	9	259	2	266	2.1e-71	234.8	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2919293427	69	22.94	5	62	172	224	4.6e-02	7.4	COG1814	Predicted Fe2+/Mn2+ transporter, VIT1/CCC1 family	229
2919293428	622	97.74	13	491	7	396	3.6e-83	273.5	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2919293429	166	89.36	20	157	15	140	3.0e-29	95.7	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
2919293430	391	99.75	1	391	1	393	6.7e-121	398.3	COG0183	Acetyl-CoA acetyltransferase	392
2919293431	699	25.53	601	697	188	271	5.6e-111	24.9	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
2919293431	699	87.84	295	607	2	290	5.6e-111	339.2	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
2919293431	699	90.19	1	282	9	247	2.1e-52	172.2	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2919293432	231	98.73	1	231	3	236	9.5e-87	284.3	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2919293433	261	98.43	5	251	5	254	5.6e-82	269.1	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2919293434	440	95.36	20	336	9	316	2.5e-72	238.3	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2919293435	317	98.34	2	317	3	298	1.6e-80	265.1	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2919293436	410	95.9	8	392	8	358	3.4e-44	145.5	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2919293437	547	97.36	3	546	8	560	2.3e-116	383.5	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
2919293438	228	94.04	1	216	4	208	2.8e-21	70.4	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2919293439	573	91.9	32	566	6	459	1.4e-99	328.4	COG2272	Carboxylesterase type B	491
2919293440	355	75	199	344	27	125	1.1e-23	76.8	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2919293441	493	98.59	9	493	8	497	0.0e+00	593.1	COG0397	Uncharacterized conserved protein YdiU, UPF0061 family	488
2919293442	137	83.69	5	137	12	129	1.3e-52	171.4	COG0229	Peptide methionine sulfoxide reductase MsrB	140
2919293443	179	98.33	1	179	1	177	9.3e-59	193.1	COG2917	Intracellular septation protein A	180
2919293444	86	85.56	1	86	5	81	9.9e-28	90.7	COG0271	Stress-induced morphogen (activity unknown)	90
2919293445	261	66.46	6	261	92	307	1.4e-41	136.8	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
2919293446	247	72.39	1	246	15	250	7.1e-43	140.9	COG3503	Uncharacterized membrane protein	323
2919293448	83	94.67	1	73	1	71	3.1e-31	100.9	COG0361	Translation initiation factor IF-1	75
2919293449	389	95.81	15	389	9	374	2.5e-110	362.9	COG3448	CBS-domain-containing membrane protein	382
2919293450	395	93.99	10	384	9	352	2.0e-51	169.3	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2919293451	287	97.67	2	287	3	296	1.7e-79	261.7	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
2919293452	332	96.28	10	323	11	321	4.4e-79	260.2	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
2919293453	257	99.61	1	255	2	254	1.5e-82	271	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
2919293454	237	98.73	3	237	4	237	5.4e-81	265.5	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
2919293455	283	98.45	8	277	3	256	5.8e-76	249.1	COG0688	Phosphatidylserine decarboxylase	239
2919293457	271	95.22	5	271	11	269	2.5e-100	329.4	COG3741	N-formylglutamate amidohydrolase	272
2919293458	460	98.58	1	452	1	418	1.6e-84	278	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
2919293459	431	91.15	29	428	30	400	5.1e-112	368.8	COG1228	Imidazolonepropionase or related amidohydrolase	406
2919293460	209	88.66	1	190	4	175	3.2e-45	148.7	COG3758	Various environmental stresses-induced protein Ves (function unknown)	193
2919293461	285	71.24	4	251	22	234	1.7e-32	107.1	COG5285	Ectoine hydroxylase-related dioxygenase, phytanoyl-CoA dioxygenase (PhyH) family	299
2919293462	577	98.22	16	577	5	555	0.0e+00	974.2	COG2987	Urocanate hydratase	561
2919293463	512	99.2	5	502	3	496	0.0e+00	663.4	COG2986	Histidine ammonia-lyase	498
2919293464	270	97.91	25	261	5	238	2.6e-70	230.7	COG2188	DNA-binding transcriptional regulator, GntR family	236
2919293465	259	98.01	1	256	3	248	2.3e-98	322.9	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
2919293466	278	96.51	23	277	6	254	3.4e-70	230.5	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
2919293467	321	88.96	1	319	9	306	4.2e-47	155.3	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2919293468	460	82.74	61	460	62	387	6.8e-54	178.2	COG0642	Signal transduction histidine kinase	336
2919293469	228	98.71	2	225	1	229	1.7e-76	250.9	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2919293471	155	91.25	4	155	8	153	5.5e-16	53.3	COG3678	Periplasmic protein refolding chaperone Spy/CpxP family	160
2919293472	280	86.36	94	270	8	121	4.6e-17	55.7	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2919293473	423	87.67	3	423	36	355	6.7e-71	232.4	COG1858	Cytochrome c peroxidase	364
2919293477	129	47.69	35	128	1	62	5.3e-07	24.7	COG1396	Transcriptional regulator, contains XRE-family HTH domain	120
2919293478	505	80.99	5	286	15	244	2.8e-22	70.8	COG4584	Transposase	278
2919293479	267	92.69	4	250	15	255	1.8e-50	166.3	COG1484	DNA replication protein DnaC	254
2919293481	224	97.3	5	223	4	219	4.5e-45	148.5	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
2919293482	236	96.31	2	236	9	243	1.9e-92	303.1	COG2227	2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase	243
2919293483	214	86.43	5	210	27	198	3.9e-49	161.8	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
2919293484	888	99.75	1	859	2	812	0.0e+00	1177	COG0188	DNA gyrase/topoisomerase IV, subunit A	804
2919293485	369	99.19	1	369	3	369	0.0e+00	445.7	COG1932	Phosphoserine aminotransferase	365
2919293486	365	96.04	1	99	2	98	9.1e-26	84	COG1605	Chorismate mutase	101
2919293486	365	97.5	91	365	3	275	7.5e-91	298.4	COG0077	Prephenate dehydratase	279
2919293487	290	98.92	1	283	3	278	8.0e-83	272.1	COG0287	Prephenate dehydrogenase	279
2919293488	676	96.43	447	670	5	220	2.9e-77	253	COG0283	Cytidylate kinase	222
2919293488	676	96.98	6	446	11	427	0.0e+00	464.7	COG0128	5-enolpyruvylshikimate-3-phosphate synthase	428
2919293489	561	99.09	1	551	2	546	0.0e+00	723.4	COG0539	Ribosomal protein S1	541
2919293490	110	96.81	1	94	2	92	4.5e-35	114.1	COG0776	Bacterial nucleoid DNA-binding protein	94
2919293491	109	76.53	1	78	23	97	3.2e-14	46.8	COG5416	Uncharacterized integral membrane protein	98
2919293492	385	98.2	2	385	4	385	1.2e-91	301.7	COG2956	Lipopolysaccharide biosynthesis regulator YciM, contains six TPR domains and a predicted metal-binding C-terminal domain	389
2919293493	153	4.41	15	139	829	879	3.0e-03	9.9	COG0587	DNA polymerase III, alpha subunit	1139
2919293494	981	84.85	805	957	16	155	1.2e-62	72.4	COG2111	Multisubunit Na+/H+ antiporter, MnhB subunit	162
2919293494	981	85.25	3	587	2	527	0.0e+00	579.6	COG1009	NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit	606
2919293494	981	98.79	610	783	2	164	1.2e-62	147.5	COG2111	Multisubunit Na+/H+ antiporter, MnhB subunit	162
2919293495	121	98.25	1	117	1	112	2.1e-35	115.2	COG1006	Multisubunit Na+/H+ antiporter, MnhC subunit	115
2919293496	573	99.21	12	556	2	503	3.8e-116	381.7	COG0651	Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit	504
2919293497	183	98.73	25	183	3	158	2.3e-35	116.2	COG1863	Multisubunit Na+/H+ antiporter, MnhE subunit	158
2919293498	92	97.75	4	91	3	89	6.6e-28	91.1	COG2212	Multisubunit Na+/H+ antiporter, MnhF subunit	89
2919293499	132	84.07	13	120	2	96	5.9e-27	88.2	COG1320	Multisubunit Na+/H+ antiporter, MnhG subunit	113
2919293500	1216	92.57	694	1216	2	524	0.0e+00	664	COG0146	N-methylhydantoinase B/oxoprolinase/acetone carboxylase, alpha subunit	563
2919293500	1216	99.71	9	682	2	678	0.0e+00	769.3	COG0145	N-methylhydantoinase A/oxoprolinase/acetone carboxylase, beta subunit	674
2919293501	184	85.43	4	184	30	199	1.3e-73	240.8	COG5631	Predicted transcription regulator, contains HTH domain, MarR family	199
2919293502	327	97.89	1	327	3	327	1.2e-62	206.3	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
2919293503	169	91.53	1	168	5	166	4.5e-23	75.6	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
2919293504	434	98.68	52	433	4	377	8.4e-93	305.2	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
2919293505	127	94.44	1	123	4	122	1.1e-31	103.7	COG0239	Fluoride ion exporter CrcB/FEX, affects chromosome condensation	126
2919293506	287	93.17	55	287	6	196	1.2e-58	192.1	COG1611	Predicted Rossmann fold nucleotide-binding protein	205
2919293509	399	46.74	209	390	6	184	6.6e-22	28.5	COG0477	MFS family permease	338
2919293509	399	51.7	2	222	17	214	6.6e-22	49.6	COG0477	MFS family permease	338
2919293510	617	87.53	184	607	21	413	1.6e-99	328	COG1322	DNA anti-recombination protein (rearrangement mutator) RmuC	448
2919293511	327	99.39	2	322	2	326	1.3e-105	347.1	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
2919293512	470	99.53	29	470	3	424	1.1e-84	278.8	COG1055	Na+/H+ antiporter NhaD or related arsenite permease	424
2919293513	406	89.76	1	405	10	377	5.1e-103	338.9	COG1488	Nicotinic acid phosphoribosyltransferase	405
2919293514	160	94.24	23	158	6	136	9.5e-34	110.4	COG0824	Acyl-CoA thioesterase FadM	137
2919293515	310	89.05	1	309	6	314	1.9e-74	244.8	COG0123	Acetoin utilization deacetylase AcuC or a related deacetylase	340
2919293516	182	67.09	2	114	48	153	1.6e-07	25.9	COG5490	Uncharacterized protein	158
2919293517	350	99.34	42	350	2	300	2.4e-60	198.6	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
2919293518	252	99.25	1	248	1	266	1.4e-50	166.5	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2919293519	960	64.56	470	956	214	641	1.6e-120	397	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2919293523	473	97.29	1	473	9	475	0.0e+00	475.9	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
2919293524	501	97.02	1	480	4	459	0.0e+00	610.5	COG0034	Glutamine phosphoribosylpyrophosphate amidotransferase	470
2919293525	162	86.26	1	161	2	158	1.8e-33	110	COG1286	Uncharacterized membrane protein, required for colicin V production	182
2919293526	290	95.8	35	289	2	229	4.1e-19	55.4	COG3147	Cell division protein DedD (periplasmic protein involved in septation)	226
2919293527	441	96.74	2	431	6	420	4.2e-126	415.4	COG0285	Folylpolyglutamate synthase/Dihydropteroate synthase	427
2919293528	127	93.16	3	120	3	111	2.4e-29	96	COG1393	Arsenate reductase and related proteins, glutaredoxin family	117
2919293529	220	83.8	2	157	20	169	3.3e-27	89.5	COG3134	Uncharacterized conserved protein YcfJ, contains glycine zipper 2TM domain	179
2919293530	105	97.87	12	105	2	93	7.0e-40	129.4	COG3123	Uncharacterized conserved protein YaiE, UPF0345 family	94
2919293531	445	95.78	9	427	5	390	0.0e+00	451.7	COG0137	Argininosuccinate synthase	403
2919293532	357	97.28	1	357	3	288	1.4e-85	280.8	COG0812	UDP-N-acetylenolpyruvoylglucosamine reductase	291
2919293533	161	98.18	1	161	4	165	1.6e-63	208	COG1666	Uncharacterized conserved protein YajQ, UPF0234 family	165
2919293534	233	60.47	40	232	84	213	5.4e-36	118.5	COG3577	Predicted aspartyl protease	215
2919293535	339	22.73	181	270	261	340	3.8e-17	8.5	COG2206	HD-GYP domain, c-di-GMP phosphodiesterase class II (or its inactivated variant)	344
2919293535	339	26.14	24	173	156	247	3.8e-17	46.6	COG2206	HD-GYP domain, c-di-GMP phosphodiesterase class II (or its inactivated variant)	344
2919293536	230	97.07	2	205	6	204	1.1e-68	225.2	COG0344	Phospholipid biosynthesis protein PlsY, probable glycerol-3-phosphate acyltransferase	200
2919293537	163	97.42	9	161	2	152	5.3e-42	137.2	COG2606	Cys-tRNA(Pro) deacylase, prolyl-tRNA editing enzyme YbaK/EbsC	155
2919293538	319	97.01	9	303	6	297	9.3e-51	167.4	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919293539	332	96.87	1	331	9	317	3.3e-84	276.9	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2919293540	474	77.51	15	455	40	363	3.6e-41	135.6	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
2919293541	353	98.12	1	352	1	314	1.5e-96	317.2	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
2919293542	302	98.98	9	302	2	293	5.1e-41	135.4	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2919293543	300	99.58	63	300	1	238	6.1e-106	347.3	COG1186	Protein chain release factor B	239
2919293544	224	94.12	2	218	3	210	3.0e-51	168.5	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
2919293545	918	98.73	16	911	11	866	0.0e+00	787.1	COG0308	Aminopeptidase N	859
2919293546	335	98.48	4	335	3	325	0.0e+00	463.5	COG0158	Fructose-1,6-bisphosphatase	326
2919293549	103	32.75	5	99	46	101	5.2e-07	24.5	COG0629	Single-stranded DNA-binding protein	167
2919293551	144	59.09	14	142	1	78	5.8e-22	72.5	COG0789	DNA-binding transcriptional regulator, MerR family	124
2919293552	108	96.81	13	106	2	92	5.9e-34	110.4	COG0776	Bacterial nucleoid DNA-binding protein	94
2919293553	815	100	148	814	1	652	0.0e+00	655.6	COG0072	Phenylalanyl-tRNA synthetase beta subunit	650
2919293554	350	98.81	1	348	5	337	1.9e-115	380.1	COG0016	Phenylalanyl-tRNA synthetase alpha subunit	335
2919293555	119	99.15	1	118	1	117	2.2e-55	180.1	COG0292	Ribosomal protein L20	118
2919293556	67	98.46	1	65	1	64	1.9e-28	93	COG0291	Ribosomal protein L35	65
2919293557	178	90.34	1	160	18	176	2.1e-68	223.5	COG0290	Translation initiation factor IF-3	176
2919293558	639	98.32	34	639	4	587	0.0e+00	880.3	COG0441	Threonyl-tRNA synthetase	589
2919293559	443	39.19	255	442	288	472	0.0e+00	262.8	COG2224	Isocitrate lyase	433
2919293559	443	54.66	8	264	5	262	0.0e+00	363.1	COG2224	Isocitrate lyase	433
2919293560	140	94.17	8	136	4	116	3.1e-21	70	COG2105	Uncharacterized conserved protein YtfP, gamma-glutamylcyclotransferase (GGCT)/AIG2-like family	120
2919293561	321	96.68	6	313	6	296	1.1e-36	120.6	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2919293562	173	76.42	4	173	11	172	4.1e-53	174.2	COG0684	Regulator of RNase E activity RraA	210
2919293563	106	36.97	2	106	109	196	3.4e-26	86.7	COG5531	Chromatin remodeling complex protein RSC6, contains SWIB domain	237
2919293564	751	96.4	19	751	28	750	7.2e-119	391.9	COG4774	Outer membrane receptor for monomeric catechols	750
2919293565	230	99.13	1	230	3	229	3.3e-80	263.1	COG3128	Predicted 2-oxoglutarate- and Fe(II)-dependent dioxygenase YbiX	229
2919293566	380	95.84	17	374	2	347	3.0e-94	309.7	COG1304	FMN-dependent dehydrogenase, includes L-lactate dehydrogenase and type II isopentenyl diphosphate isomerase	360
2919293567	90	93.65	1	61	1	59	5.0e-15	49.2	COG2906	Bacterioferritin-associated ferredoxin	63
2919293568	229	66.42	41	229	90	271	2.9e-24	79.9	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
2919293569	238	96.76	10	224	3	211	3.5e-53	175	COG0811	Biopolymer transport protein ExbB/TolQ	216
2919293570	137	98.56	1	137	1	137	3.7e-44	144.3	COG0848	Biopolymer transport protein ExbD	137
2919293571	74	68.25	10	74	21	63	1.3e-15	51.5	COG4256	Hemin uptake protein HemP	63
2919293572	135	97.16	1	135	2	138	6.8e-44	143.7	COG3193	Uncharacterized conserved protein GlcG, DUF336 family	141
2919293573	231	92.67	1	230	17	231	1.9e-46	152.6	COG0670	Integral membrane protein, interacts with FtsH	233
2919293575	487	98.17	24	480	9	436	9.6e-105	344.9	COG2265	tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family	432
2919293577	157	94.3	2	156	4	152	2.3e-40	132.4	COG1522	DNA-binding transcriptional regulator, Lrp family	154
2919293578	1248	99.5	33	455	3	403	0.0e+00	535.4	COG0506	Proline dehydrogenase	391
2919293578	1248	99.74	458	1248	3	773	0.0e+00	1129.9	COG4230	Delta 1-pyrroline-5-carboxylate dehydrogenase	769
2919293580	195	93.41	9	187	11	180	7.6e-13	42.5	COG1514	2'-5' RNA ligase	180
2919293581	538	98.99	3	205	2	197	3.4e-70	229.7	COG0518	GMP synthase - Glutamine amidotransferase domain	198
2919293581	538	99.68	206	538	2	316	0.0e+00	495.6	COG0519	GMP synthase, PP-ATPase domain/subunit	315
2919293582	144	92.54	1	138	3	126	3.2e-12	41	COG4113	Predicted nucleic acid-binding protein, contains PIN domain	134
2919293583	86	73.81	1	85	1	62	1.4e-14	48.2	COG4118	Antitoxin component of toxin-antitoxin stability system, DNA-binding transcriptional repressor	84
2919293584	491	82.57	1	211	13	192	3.8e-108	147.7	COG0516	IMP dehydrogenase/GMP reductase	170
2919293584	491	100	257	480	1	218	3.8e-108	211.7	COG0516	IMP dehydrogenase/GMP reductase	170
2919293585	172	30.53	9	169	55	174	3.1e-02	7.9	COG2948	Type IV secretory pathway, VirB10 components	360
2919293586	115	92.93	9	102	3	94	8.2e-17	55	COG2914	Putative antitoxin component PasI (RatB) of the RatAB toxin-antitoxin module, ubiquitin-RnfH superfamily	99
2919293587	146	98.63	1	146	1	144	6.5e-50	162.7	COG2867	Ribosome association toxin PasT (RatA) of the RatAB toxin-antitoxin module	146
2919293588	157	96.08	3	157	5	151	1.1e-61	201.2	COG0691	tmRNA-binding protein	153
2919293589	123	83.33	1	123	24	138	5.3e-44	143.7	COG4315	Predicted lipoprotein with conserved Yx(FWY)xxD motif (function unknown)	138
2919293590	183	86.56	2	159	21	181	1.0e-45	149.7	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2919293591	302	95.33	12	300	12	256	7.0e-48	156.9	COG5662	Transmembrane transcriptional regulator (anti-sigma factor RsiW)	256
2919293592	364	98.49	3	332	5	265	1.7e-64	210.6	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
2919293593	291	96.68	2	290	5	295	5.1e-24	79.2	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2919293594	608	99.5	2	608	2	601	0.0e+00	955.2	COG1217	Predicted membrane GTPase involved in stress response	603
2919293595	330	93.23	4	307	4	292	1.8e-90	297.5	COG0130	tRNA U55 pseudouridine synthase TruB, may also work on U342 of tmRNA	271
2919293596	123	94.12	1	120	5	116	1.8e-33	109.3	COG0858	Ribosome-binding factor A	118
2919293597	955	99.29	453	955	3	559	0.0e+00	543.8	COG0532	Translation initiation factor IF-2, a GTPase	509
2919293598	494	36.09	382	492	63	110	7.0e-05	17.5	COG3743	 Predicted 5' DNA nuclease, flap endonuclease-1-like, helix-3-turn-helix (H3TH) domain	133
2919293598	494	97.49	159	373	2	195	4.4e-78	254.7	COG0195	Transcription antitermination factor NusA, contains S1 and KH domains	190
2919293599	198	78.57	2	162	10	130	1.2e-24	79.8	COG0779	Ribosome maturation factor RimP	153
2919293600	1142	29.57	868	1129	260	403	2.1e-14	20.8	COG1061	Superfamily II DNA or RNA helicase	442
2919293600	1142	32.85	649	846	37	196	2.1e-14	24.7	COG1061	Superfamily II DNA or RNA helicase	442
2919293601	133	51.33	23	125	45	121	3.4e-06	21.7	COG0526	Thiol-disulfide isomerase or thioredoxin	127
2919293602	426	24.39	105	164	114	153	2.0e-32	5.6	COG2010	Cytochrome c, mono- and diheme variants	150
2919293602	426	25.61	5	80	49	90	2.0e-32	12.9	COG2010	Cytochrome c, mono- and diheme variants	150
2919293602	426	56.71	297	420	54	146	2.0e-32	56.9	COG2010	Cytochrome c, mono- and diheme variants	150
2919293602	426	99.39	123	298	1	163	2.0e-32	43.6	COG2010	Cytochrome c, mono- and diheme variants	150
2919293603	270	71.11	146	255	28	123	1.1e-43	69.2	COG2863	Cytochrome c553	121
2919293603	270	94.07	10	158	9	135	1.1e-43	74.2	COG2863	Cytochrome c553	121
2919293604	491	98.68	1	479	3	452	0.0e+00	444	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
2919293606	243	89.1	10	157	2	140	2.8e-09	31.1	COG2165	Type II secretory pathway, pseudopilin PulG	149
2919293607	436	51.28	1	173	5	84	7.5e-04	14.4	COG2165	Type II secretory pathway, pseudopilin PulG	149
2919293608	409	79.49	1	181	4	127	8.4e-08	27.2	COG2165	Type II secretory pathway, pseudopilin PulG	149
2919293609	738	45.36	482	539	50	93	1.6e-01	7.7	COG4842	Uncharacterized conserved protein YukE	97
2919293609	738	48.45	556	622	15	61	1.6e-01	5.1	COG4842	Uncharacterized conserved protein YukE	97
2919293610	240	37.18	1	140	12	69	3.9e-04	15	COG2165	Type II secretory pathway, pseudopilin PulG	149
2919293611	124	14.38	1	117	197	281	2.7e-04	13.8	COG4625	Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain	577
2919293612	422	98.74	4	415	3	395	2.0e-90	297.3	COG1459	Type II secretory pathway, component PulF	397
2919293613	527	97.64	37	526	12	507	0.0e+00	440.6	COG2804	Type II secretory pathway ATPase GspE/PulE or T4P pilus assembly pathway ATPase PilB	500
2919293614	501	94.16	6	265	15	272	3.7e-44	144.9	COG3267	Type II secretory pathway, component ExeA (predicted ATPase)	269
2919293615	153	23.09	3	152	306	417	1.8e-06	21.1	COG4783	Putative Zn-dependent protease, contains TPR repeats	484
2919293616	598	12.99	58	166	28	107	1.8e-54	9.2	COG1450	Type II secretory pathway component GspD/PulD (secretin)	587
2919293616	598	43.83	163	598	306	575	1.8e-54	169.3	COG1450	Type II secretory pathway component GspD/PulD (secretin)	587
2919293620	308	50.64	9	197	5	83	2.3e-08	27.9	COG2165	Type II secretory pathway, pseudopilin PulG	149
2919293621	277	17.31	12	171	7	33	6.2e-06	20.2	COG2165	Type II secretory pathway, pseudopilin PulG	149
2919293622	257	84.62	1	160	13	144	5.5e-03	10.2	COG2165	Type II secretory pathway, pseudopilin PulG	149
2919293623	387	97.72	4	385	2	344	2.0e-63	209	COG0673	Predicted dehydrogenase	342
2919293624	337	96.04	4	317	7	273	6.9e-41	126.8	COG1082	Sugar phosphate isomerase/epimerase	274
2919293625	326	96.33	2	326	9	323	1.7e-61	202	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
2919293626	349	95.61	31	349	8	312	5.4e-88	289	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
2919293627	496	98.6	1	495	7	500	0.0e+00	594.2	COG1129	ABC-type sugar transport system, ATPase component	500
2919293628	416	96.77	77	398	7	306	9.7e-72	235.6	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
2919293630	160	56.49	19	132	45	118	4.2e-11	36.5	COG1917	Cupin domain protein related to quercetin dioxygenase	131
2919293631	132	86.96	66	131	4	63	9.7e-22	16.3	COG1942	Phenylpyruvate tautomerase PptA, 4-oxalocrotonate tautomerase family	69
2919293631	132	97.1	1	68	1	67	9.7e-22	53.3	COG1942	Phenylpyruvate tautomerase PptA, 4-oxalocrotonate tautomerase family	69
2919293632	311	98.34	9	306	2	297	2.9e-53	175.6	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919293633	240	74.9	29	239	51	229	2.2e-08	27.4	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
2919293634	150	75.33	1	130	21	133	6.7e-24	78.6	COG1959	DNA-binding transcriptional regulator, IscR family	150
2919293635	317	97.72	6	316	2	301	8.3e-43	140.6	COG0492	Thioredoxin reductase	305
2919293636	188	78.24	18	154	2	134	2.3e-18	60.5	COG0645	Predicted kinase	170
2919293637	218	97.17	6	218	2	207	4.9e-60	196.8	COG3531	Predicted protein-disulfide isomerase , contains CxxC motif	212
2919293639	288	82.31	12	276	14	227	8.8e-18	58.7	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2919293640	297	98.01	2	296	2	296	2.2e-70	231.8	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919293642	330	98.43	7	329	5	318	1.1e-88	291.5	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2919293645	297	96.01	6	296	3	291	5.8e-66	217.3	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919293646	177	54.95	14	157	35	134	1.5e-05	18.9	COG1514	2'-5' RNA ligase	180
2919293652	328	60.47	89	322	79	260	4.0e-25	82.4	COG3221	ABC-type phosphate/phosphonate transport system, periplasmic component	299
2919293653	219	94.82	3	205	5	187	3.2e-57	187.6	COG0066	3-isopropylmalate dehydratase small subunit	191
2919293654	472	99.3	2	469	3	428	0.0e+00	540.8	COG0065	Homoaconitase/3-isopropylmalate dehydratase large subunit	423
2919293655	300	98.98	12	299	1	292	2.6e-38	126.4	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2919293656	341	97.81	17	340	6	317	4.4e-94	309.2	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2919293657	299	98.67	3	299	3	299	1.7e-74	245.3	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919293658	205	28.69	58	204	151	292	3.3e-07	23.4	COG0248	Exopolyphosphatase/pppGpp-phosphohydrolase	492
2919293659	199	92.57	14	189	11	172	2.3e-56	184	COG3040	Bacterial lipocalin	174
2919293660	544	99.25	5	542	2	531	0.0e+00	692.2	COG4172	ABC-type microcin C transport system, duplicated ATPase component YejF	534
2919293661	348	97.95	6	347	7	340	0.0e+00	494.9	COG4239	ABC-type microcin C transport system, permease component YejE	341
2919293662	343	99.18	1	343	1	361	0.0e+00	532	COG4174	ABC-type microcin C transport system, permease component YejB	364
2919293663	608	97.74	1	599	9	569	2.7e-114	376.9	COG4166	ABC-type oligopeptide transport system, periplasmic component	562
2919293664	266	97.68	1	264	1	253	1.9e-108	355.8	COG0623	Enoyl-[acyl-carrier-protein] reductase (NADH)	259
2919293665	287	53.25	4	287	147	408	3.7e-31	98.2	COG1793	ATP-dependent DNA ligase	444
2919293666	186	77.07	1	186	42	199	5.4e-54	177.6	COG2335	Uncaracterized surface protein containing fasciclin (FAS1) repeats	187
2919293667	788	98.99	140	758	2	588	0.0e+00	712.8	COG1982	Arginine/lysine/ornithine decarboxylase	557
2919293668	141	95.74	1	141	4	138	1.3e-15	52.1	COG1585	Membrane protein implicated in regulation of membrane protease activity	140
2919293669	305	92.69	1	297	8	286	6.1e-78	253.3	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
2919293675	341	69.73	31	308	12	269	5.5e-13	38	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
2919293676	266	68.91	12	238	48	231	1.0e-14	48.4	COG0767	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, permease component MlaE	267
2919293677	154	92.42	8	132	1	122	9.8e-30	97.6	COG0789	DNA-binding transcriptional regulator, MerR family	124
2919293678	223	70.57	1	220	10	220	2.3e-37	123.1	COG1230	Co/Zn/Cd efflux system component	296
2919293680	212	66.78	14	212	14	208	7.2e-38	124.4	COG1284	Uncharacterized membrane-anchored protein YitT, contains DUF161 and DUF2179 domains	289
2919293681	1185	55.37	616	741	108	241	2.3e-48	48.1	COG2202	PAS domain	232
2919293681	1185	58.26	482	620	102	242	2.3e-48	48.7	COG2202	PAS domain	232
2919293681	1185	67.12	707	1183	202	646	1.0e-115	380.8	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2919293681	1185	78.93	270	493	50	240	2.3e-48	70.9	COG2202	PAS domain	232
2919293684	475	98.04	13	465	2	452	2.6e-34	112.7	COG1538	Outer membrane protein TolC	457
2919293685	460	28.93	192	334	337	476	1.0e-67	102.1	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
2919293685	460	34.71	3	202	1	168	1.0e-67	127.2	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
2919293686	141	76.58	10	138	37	157	3.9e-34	112.2	COG4454	Uncharacterized copper-binding protein, cupredoxin-like subfamily	158
2919293687	178	89.26	27	175	16	148	5.2e-51	166.3	COG3019	Uncharacterized conserved protein	149
2919293688	123	80.56	15	121	20	106	4.0e-22	72.7	COG5569	Periplasmic Cu and Ag efflux protein CusF	108
2919293689	336	92.53	1	334	10	331	5.2e-85	279.6	COG3191	L-aminopeptidase/D-esterase	348
2919293690	173	86.42	15	156	14	153	7.4e-11	36.8	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2919293691	527	95.65	1	520	14	519	2.4e-126	416.7	COG4943	Environmental sensor c-di-GMP phosphodiesterase, contains periplasmic CSS-motif sensor and cytoplasmic EAL domain	524
2919293696	553	99.44	3	536	3	534	0.0e+00	589.9	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
2919293697	595	74.04	1	493	29	413	0.0e+00	494	COG0513	Superfamily II DNA and RNA helicase	513
2919293698	237	69.57	9	233	4	195	2.6e-23	76.7	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
2919293699	362	33.66	2	304	470	740	8.0e-12	37.4	COG2374	Predicted extracellular nuclease	798
2919293701	579	98.04	1	411	1	400	0.0e+00	538.7	COG4651	Predicted Kef-type K+ transport protein, K+/H+ antiporter domain	408
2919293704	642	64.92	51	432	110	320	1.3e-35	117.7	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
2919293706	90	95.74	1	90	2	91	1.5e-35	115.6	COG0776	Bacterial nucleoid DNA-binding protein	94
2919293707	364	99.14	1	364	2	346	1.7e-125	412.8	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
2919293708	188	93.3	1	187	12	192	6.7e-48	157.5	COG0558	Phosphatidylglycerophosphate synthase	192
2919293709	665	99.67	3	664	3	598	0.0e+00	690.2	COG0322	Excinuclease UvrABC, nuclease subunit	581
2919293710	326	97.81	5	325	6	317	3.7e-102	335.8	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2919293711	326	97.49	7	324	6	316	6.6e-87	285.5	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2919293712	326	70.22	13	323	2	291	6.0e-58	190.9	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
2919293713	401	98.25	2	400	8	401	0.0e+00	445.1	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
2919293714	300	96.35	3	298	5	294	1.8e-55	182.9	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919293715	382	98.38	10	382	4	367	2.4e-88	290.6	COG4394	Uncharacterized protein	370
2919293716	184	97.71	1	128	3	130	7.8e-40	129.7	COG0231	Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)	131
2919293717	463	98.41	9	463	3	436	1.2e-126	417.3	COG0621	tRNA A37 methylthiotransferase MiaB	437
2919293718	177	93.26	5	176	4	183	3.8e-57	186.4	COG5394	Polyhydroxyalkanoate (PHA) synthesis regulator protein, binds DNA and PHA	193
2919293719	250	96.75	1	250	3	240	5.2e-59	193.4	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
2919293720	328	21.09	239	321	93	177	4.0e-34	40.5	COG3391	DNA-binding beta-propeller fold protein YncE	381
2919293720	328	62.78	7	254	78	330	4.0e-34	79.8	COG3391	DNA-binding beta-propeller fold protein YncE	381
2919293721	226	67.54	2	222	80	260	4.8e-24	78.5	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
2919293722	337	94.31	15	329	9	273	4.5e-47	154.3	COG3000	Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily	271
2919293723	316	64.75	1	310	66	313	1.2e-01	5.5	COG0477	MFS family permease	338
2919293724	273	93	3	263	4	242	1.7e-56	185.4	COG1058	Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA	255
2919293725	471	99.55	3	471	2	445	0.0e+00	571.2	COG0174	Glutamine synthetase	443
2919293727	363	95.04	10	363	10	354	1.3e-123	406.6	COG3852	Signal transduction histidine kinase, nitrogen specific	363
2919293728	545	98.07	1	545	5	462	0.0e+00	592.2	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
2919293730	259	99.61	1	259	1	258	1.3e-80	264.6	COG0708	Exonuclease III	261
2919293731	162	95.29	2	161	4	165	1.8e-46	152.3	COG0262	Dihydrofolate reductase	167
2919293732	202	13.55	111	199	185	239	1.6e-03	4	COG0786	Na+/glutamate symporter	404
2919293732	202	14.04	20	111	153	209	1.6e-03	10.8	COG0786	Na+/glutamate symporter	404
2919293733	289	98.9	17	289	4	273	5.6e-121	397	COG0207	Thymidylate synthase	268
2919293734	170	86.24	1	166	6	168	2.5e-10	32.3	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
2919293737	443	98.19	4	440	7	441	2.5e-70	232.1	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
2919293738	287	95.97	1	287	8	293	2.5e-69	228.1	COG1175	ABC-type sugar transport system, permease component	295
2919293739	279	97.17	2	279	9	283	7.9e-67	219.7	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
2919293740	347	100	1	338	1	350	0.0e+00	456.6	COG3839	ABC-type sugar transport system, ATPase component	338
2919293741	244	97.97	4	244	4	244	4.4e-69	227	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
2919293742	463	95.36	1	462	18	469	1.8e-127	420.1	COG0246	Mannitol-1-phosphate/altronate dehydrogenases	473
2919293743	311	93.18	182	309	3	125	4.1e-29	94.7	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2919293744	494	98.01	1	494	5	496	0.0e+00	474.9	COG1070	Sugar (pentulose or hexulose) kinase	502
2919293745	344	94.94	15	336	4	303	1.1e-40	133.6	COG0524	Sugar or nucleoside kinase, ribokinase family	311
2919293747	162	56.79	21	152	63	154	6.0e-10	34	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2919293749	155	80.86	16	154	26	156	4.7e-13	43.6	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2919293750	471	94.88	7	471	22	466	1.9e-114	377.2	COG0277	FAD/FMN-containing dehydrogenase	459
2919293751	149	89.31	8	140	12	128	1.7e-44	145.1	COG3308	Uncharacterized membrane protein	131
2919293752	416	91.75	10	302	7	284	8.3e-55	180	COG1295	Uncharacterized membrane protein, BrkB/YihY/UPF0761 family (not an RNase)	303
2919293753	115	98.1	11	115	2	104	1.1e-50	164.7	COG4323	Uncharacterized protein	105
2919293754	272	96.95	2	272	8	293	1.0e-40	134.1	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2919293755	436	98.83	3	431	5	426	0.0e+00	609	COG2873	O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent	426
2919293756	149	38.65	68	140	9	71	9.2e-23	26.9	COG0517	CBS domain	117
2919293756	149	93.25	1	121	11	162	9.2e-23	58.9	COG0517	CBS domain	117
2919293757	727	65.16	244	726	214	645	2.5e-107	353.3	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2919293758	365	96.76	2	356	2	359	0.0e+00	495.9	COG0082	Chorismate synthase	369
2919293759	601	97.35	12	599	12	525	2.7e-83	274.4	COG0737	2',3'-cyclic-nucleotide 2'-phosphodiesterase/5'- or 3'-nucleotidase, 5'-nucleotidase family	517
2919293760	300	96.01	1	294	6	294	5.2e-35	115.2	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2919293761	149	94.87	1	149	1	148	5.5e-62	202.5	COG1327	Transcriptional regulator NrdR, contains Zn-ribbon and ATP-cone domains	156
2919293762	414	98.31	3	414	7	414	0.0e+00	636.6	COG0112	Glycine/serine hydroxymethyltransferase	413
2919293764	271	69.31	2	195	18	227	1.9e-20	67.5	COG0741	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)	296
2919293768	777	90.58	3	692	66	709	0.0e+00	759.7	COG0557	Exoribonuclease R	706
2919293769	324	96.61	44	320	7	291	5.6e-47	154.7	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2919293770	249	88.64	117	247	9	125	7.7e-14	45.4	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2919293771	508	90.62	230	508	21	281	1.6e-61	202.6	COG0063	NAD(P)H-hydrate repair enzyme Nnr, NAD(P)H-hydrate dehydratase domain	284
2919293771	508	96.1	9	224	4	200	1.0e-42	139	COG0062	NAD(P)H-hydrate repair enzyme Nnr, NAD(P)H-hydrate epimerase domain	203
2919293772	410	96.65	1	410	5	379	1.3e-64	207.5	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2919293773	451	96.47	3	451	11	474	1.8e-101	334.6	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
2919293774	250	92.97	1	250	6	243	3.3e-99	325.2	COG0052	Ribosomal protein S2	252
2919293775	308	99.66	1	303	1	296	1.9e-92	303.7	COG0264	Translation elongation factor EF-Ts	296
2919293776	240	98.32	5	240	3	236	6.6e-94	308.1	COG0528	Uridylate kinase	238
2919293777	186	98.93	1	186	3	187	2.9e-76	249.2	COG0233	Ribosome recycling factor	187
2919293778	243	91.67	2	228	22	252	7.5e-87	284.9	COG0020	Undecaprenyl pyrophosphate synthase	245
2919293779	284	98.91	1	284	1	272	2.2e-56	185.7	COG0575	CDP-diglyceride synthetase	265
2919293780	393	98.45	3	393	2	381	0.0e+00	502.8	COG0743	1-deoxy-D-xylulose 5-phosphate reductoisomerase	385
2919293781	454	99.75	1	454	1	401	3.1e-81	263.1	COG0750	Membrane-associated protease RseP, regulator of RpoE activity	375
2919293782	765	98.97	1	765	9	774	0.0e+00	717.3	COG4775	Outer membrane protein assembly factor BamA	766
2919293783	173	95.88	1	169	7	169	1.9e-38	126.4	COG2825	Periplasmic chaperone for outer membrane proteins, Skp family	170
2919293784	327	97.63	2	324	6	335	1.4e-101	327.2	COG1044	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase	338
2919293785	145	95.27	1	144	4	144	4.0e-52	170.1	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
2919293786	262	98.46	1	262	4	259	3.5e-107	351.6	COG1043	Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase	260
2919293787	387	98.95	4	384	2	377	2.3e-116	382.7	COG0763	Lipid A disaccharide synthetase	381
2919293788	210	94.06	23	210	2	191	1.6e-65	215.2	COG0164	Ribonuclease HII	199
2919293789	257	96.96	9	254	1	255	3.6e-46	151.6	COG0566	tRNA G18 (ribose-2'-O)-methylase SpoU	260
2919293790	387	98.11	10	387	4	367	0.0e+00	505.9	COG0505	Carbamoylphosphate synthase small subunit	368
2919293791	1081	93.9	566	952	1	385	0.0e+00	294.5	COG0458	Carbamoylphosphate synthase large subunit	400
2919293791	1081	100	13	423	1	410	0.0e+00	719.2	COG0458	Carbamoylphosphate synthase large subunit	400
2919293792	158	100	6	158	1	152	1.8e-60	197.5	COG0782	Transcription elongation factor, GreA/GreB family	151
2919293795	157	91.75	5	101	2	90	2.1e-28	92.1	COG1534	RNA-binding protein YhbY	97
2919293796	218	97.56	8	218	2	201	4.2e-74	242.8	COG0293	23S rRNA U2552 (ribose-2'-O)-methylase RlmE/FtsJ	205
2919293797	639	99.33	10	608	2	598	0.0e+00	880.5	COG0465	ATP-dependent Zn proteases	596
2919293798	276	94.6	6	276	8	270	1.1e-90	297.7	COG0294	Dihydropteroate synthase	274
2919293799	444	96.65	1	444	11	472	5.6e-130	428.5	COG1109	Phosphomannomutase	464
2919293800	729	44.21	3	118	111	217	3.0e-23	33	COG2202	PAS domain	232
2919293800	729	65.61	241	728	210	644	8.1e-116	381.6	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2919293800	729	76.45	75	255	58	242	3.0e-23	52.5	COG2202	PAS domain	232
2919293801	983	65.01	441	980	212	642	1.1e-115	381.1	COG5001	Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	663
2919293801	983	74.26	9	305	36	260	1.3e-17	57.2	COG3452	Extracellular (periplasmic) sensor domain CHASE (specificity unknown)	297
2919293802	279	87.71	4	279	30	286	2.3e-67	221.5	COG3176	Putative hemolysin	292
2919293803	278	99.59	27	264	1	240	1.5e-70	231.4	COG2908	UDP-2,3-diacylglucosamine pyrophosphatase LpxH	237
2919293804	359	95.6	1	339	7	397	1.9e-33	110.8	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
2919293805	686	94.71	1	672	11	672	0.0e+00	782.5	COG0855	Polyphosphate kinase	696
2919293806	153	96.93	1	153	2	159	3.0e-36	118.8	COG2062	Phosphohistidine phosphatase SixA	163
2919293808	492	99.39	3	483	3	494	5.6e-125	412	COG0248	Exopolyphosphatase/pppGpp-phosphohydrolase	492
2919293809	340	95.38	1	326	14	323	2.4e-82	270.8	COG0226	ABC-type phosphate transport system, periplasmic component	318
2919293810	329	97.45	11	327	7	312	1.4e-108	356.6	COG0573	ABC-type phosphate transport system, permease component	310
2919293811	284	97.62	2	284	6	292	6.2e-93	305.1	COG0581	ABC-type phosphate transport system, permease component	292
2919293812	260	99.21	7	260	3	254	5.5e-123	403.4	COG1117	ABC-type phosphate transport system, ATPase component	253
2919293813	233	93.47	2	232	8	236	1.3e-54	179.1	COG0704	Phosphate uptake regulator	240
2919293814	235	98.71	5	229	2	230	1.5e-86	283.7	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2919293815	447	84.77	9	441	56	389	1.0e-65	215.7	COG0642	Signal transduction histidine kinase	336
2919293816	455	93.91	1	449	17	448	1.2e-72	239	COG0534	Na+-driven multidrug efflux pump	455
2919293817	566	80.62	14	489	9	449	8.5e-08	21.8	COG1807	4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferase of PMT family	535
2919293818	84	94.67	1	84	1	71	3.7e-28	91.8	COG0254	Ribosomal protein L31	75
2919293819	420	98.82	1	419	4	420	0.0e+00	686.4	COG1158	Transcription termination factor Rho	422
2919293820	110	35.41	1	110	23	130	2.8e-33	110.1	COG3118	Negative regulator of GroEL, contains thioredoxin-like and TPR-like domains	304
2919293821	865	95.91	598	860	1	258	1.4e-21	70	COG2887	RecB family exonuclease	269
2919293822	1175	14.24	897	1119	981	1144	0.0e+00	13.7	COG1074	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)	1139
2919293822	1175	73.18	19	944	7	849	0.0e+00	440.5	COG1074	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)	1139
2919293823	455	49.14	17	233	3	202	7.7e-116	216.6	COG2081	Predicted flavoprotein YhiN	408
2919293823	455	50.12	237	449	203	406	7.7e-116	163.1	COG2081	Predicted flavoprotein YhiN	408
2919293825	668	70.6	1	640	1	413	0.0e+00	495.1	COG2812	DNA polymerase III, gamma/tau subunits	515
2919293826	110	99.05	1	107	1	104	3.8e-41	133.7	COG0718	Conserved DNA-binding protein YbaB (function unknown)	105
2919293827	196	98.48	1	196	2	196	9.7e-78	254.2	COG0353	Recombinational DNA repair protein RecR	198
2919293828	141	95.2	10	140	2	120	2.4e-34	112	COG3686	Uncharacterized conserved protein, MAPEG superfamily	125
2919293829	351	92.54	6	343	7	316	2.7e-38	126.1	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
2919293831	508	89.12	359	494	2	132	7.7e-08	25.5	COG1388	LysM repeat	124
2919293832	258	91.54	1	224	20	257	1.1e-50	166.6	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2919293834	149	93.59	1	148	3	148	2.6e-61	200.3	COG0328	Ribonuclease HI	154
2919293835	465	93.59	2	377	15	379	6.6e-48	158.1	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
2919293836	1051	99.8	2	1025	2	1013	0.0e+00	1113.3	COG0841	Multidrug efflux pump subunit AcrB	1009
2919293837	108	62.67	4	104	37	130	3.6e-13	44.2	COG0526	Thiol-disulfide isomerase or thioredoxin	127
2919293838	451	28.01	329	451	291	404	0.0e+00	100.2	COG0303	Molybdopterin biosynthesis enzyme	404
2919293838	451	71.74	14	325	7	298	0.0e+00	334.3	COG0303	Molybdopterin biosynthesis enzyme	404
2919293839	190	88.24	3	190	15	179	4.0e-14	47.3	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
2919293840	212	98.45	3	208	2	192	5.5e-55	180	COG0746	Molybdopterin-guanine dinucleotide biosynthesis protein A	192
2919293841	378	99.69	30	378	2	325	1.2e-111	366.8	COG2896	Molybdenum cofactor biosynthesis enzyme MoaA	322
2919293844	227	56.17	46	205	29	119	7.3e-04	14.3	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2919293845	332	17.81	157	239	47	72	2.0e-03	3.5	COG1664	Cytoskeletal protein CcmA, bactofilin family	146
2919293845	332	29.45	235	291	30	72	2.0e-03	4	COG1664	Cytoskeletal protein CcmA, bactofilin family	146
2919293845	332	30.82	107	197	37	81	2.0e-03	9.1	COG1664	Cytoskeletal protein CcmA, bactofilin family	146
2919293846	253	99.63	1	252	1	267	4.1e-64	210.9	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2919293848	477	98.96	2	477	3	476	0.0e+00	512	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2919293849	234	96.33	10	227	7	216	3.0e-37	122.3	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2919293850	178	97.22	1	176	1	175	2.1e-63	207.3	COG4539	Uncharacterized membrane protein YGL010W	180
2919293851	384	48.46	160	379	143	284	6.2e-07	22.5	COG0842	ABC-type multidrug transport system, permease component	286
2919293852	390	51.54	171	379	133	283	1.3e-05	18.3	COG0842	ABC-type multidrug transport system, permease component	286
2919293853	328	78.12	1	285	8	282	1.1e-37	123.7	COG1566	Multidrug resistance efflux pump	352
2919293854	480	13.91	12	105	250	313	8.0e-38	8	COG1538	Outer membrane protein TolC	457
2919293854	480	79.78	109	468	81	447	8.0e-38	122.8	COG1538	Outer membrane protein TolC	457
2919293855	273	93.93	1	268	14	276	6.7e-66	216.8	COG3687	Predicted metal-dependent hydrolase	280
2919293856	207	90.91	5	206	6	195	1.9e-17	58.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2919293857	128	97.95	6	126	3	145	8.3e-17	57.1	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
2919293858	843	93.27	2	835	52	952	0.0e+00	620.3	COG0474	Magnesium-transporting ATPase (P-type)	917
2919293859	54	96.36	1	54	1	53	3.8e-26	85.3	COG1773	Rubredoxin	55
2919293860	255	93.23	19	207	5	183	2.5e-22	73.1	COG3658	Cytochrome b	192
2919293861	174	10.37	131	160	71	87	5.0e-05	10.9	COG2010	Cytochrome c, mono- and diheme variants	150
2919293861	174	17.07	2	106	61	88	5.0e-05	10.6	COG2010	Cytochrome c, mono- and diheme variants	150
2919293863	128	57.24	27	116	61	143	9.1e-16	53	COG3212	Uncharacterized membrane protein YkoI	144
2919293864	230	99.14	1	230	1	230	1.7e-80	263.9	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2919293865	480	87.56	107	480	46	390	7.5e-40	132.2	COG0642	Signal transduction histidine kinase	336
2919293867	693	99.29	6	691	5	702	0.0e+00	982.7	COG3808	Na+ or H+-translocating membrane pyrophosphatase	703
2919293869	178	100	1	175	1	172	2.6e-70	229.9	COG0221	Inorganic pyrophosphatase	171
2919293870	511	88.94	99	511	36	413	6.5e-106	349.6	COG0840	Methyl-accepting chemotaxis protein	408
2919293871	255	97.66	1	254	1	250	2.2e-87	287	COG0121	Predicted glutamine amidotransferase	252
2919293872	485	51.14	243	465	172	373	3.3e-34	29.2	COG2814	Predicted arabinose efflux permease, MFS family	394
2919293872	485	55.44	13	237	8	226	3.3e-34	90.6	COG2814	Predicted arabinose efflux permease, MFS family	394
2919293873	63	89.86	1	63	1	62	9.2e-21	67.8	COG1942	Phenylpyruvate tautomerase PptA, 4-oxalocrotonate tautomerase family	69
2919293874	736	99.65	4	734	2	575	0.0e+00	719.5	COG2225	Malate synthase	545
2919293875	641	98.3	14	542	3	521	0.0e+00	707.8	COG4670	Acyl CoA:acetate/3-ketoacid CoA transferase	527
2919293876	311	98.67	2	304	2	298	5.2e-71	234.2	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919293877	213	96.21	5	210	3	205	1.8e-54	178.7	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2919293879	889	56.59	757	885	11	113	7.4e-06	18.9	COG4567	Two-component response regulator, ActR/RegA family, consists of REC and Fis-type HTH domains	182
2919293879	889	98.34	3	736	5	598	3.3e-102	334.8	COG4191	Signal transduction histidine kinase regulating C4-dicarboxylate transport system	603
2919293880	456	97.37	11	435	4	410	0.0e+00	508.1	COG1301	Na+/H+-dicarboxylate symporter	415
2919293881	148	98.67	1	148	1	148	5.9e-31	101.9	COG3556	Uncharacterized membrane protein	150
2919293882	97	21.72	1	96	38	123	1.6e-05	18.4	COG2959	Uncharacterized conserved protein HemX (no evidence of involvement in heme biosynthesis)	391
2919293884	569	99.48	2	569	4	581	0.0e+00	549.5	COG0018	Arginyl-tRNA synthetase	577
2919293885	218	15.36	1	84	11	51	4.0e-25	7.9	COG3087	Cell division protein FtsN	264
2919293885	218	58.43	43	218	108	263	4.0e-25	77.4	COG3087	Cell division protein FtsN	264
2919293886	218	13.78	52	105	11	41	2.4e-09	5.7	COG2761	Predicted dithiol-disulfide isomerase, DsbA family	225
2919293886	218	39.56	94	218	112	200	2.4e-09	26	COG2761	Predicted dithiol-disulfide isomerase, DsbA family	225
2919293887	219	91.91	1	200	7	165	3.6e-30	98.8	COG1934	Lipopolysaccharide export system protein LptA	173
2919293888	268	98.77	22	268	4	243	3.3e-114	374.3	COG1137	ABC-type lipopolysaccharide export system, ATPase component	243
2919293889	532	99.55	1	532	1	446	0.0e+00	469.2	COG1508	DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog	444
2919293890	160	94.96	9	144	4	135	6.5e-20	65.7	COG0824	Acyl-CoA thioesterase FadM	137
2919293891	430	98.69	2	412	3	378	2.9e-112	369.5	COG0116	23S rRNA G2445 N2-methylase RlmL	381
2919293892	161	83.8	19	153	3	121	5.1e-15	50	COG1569	Predicted nucleic acid-binding protein, contains PIN domain	142
2919293894	142	62.35	5	129	58	158	8.0e-12	40.2	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2919293896	580	95.5	39	505	22	488	5.6e-121	392.1	COG0069	Glutamate synthase domain 2	485
2919293897	284	29.49	28	142	26	89	9.0e-13	8.9	COG3318	Uncharacterized conserved protein YecA, UPF0149 family, contains C-terminal Zn-binding SEC-C motif	216
2919293897	284	50.23	136	284	108	216	9.0e-13	32.2	COG3318	Uncharacterized conserved protein YecA, UPF0149 family, contains C-terminal Zn-binding SEC-C motif	216
2919293898	478	82.06	4	442	12	473	4.1e-98	321.3	COG0659	Sulfate permease or related transporter, MFS superfamily	554
2919293900	629	60.09	8	230	12	142	8.6e-27	88.5	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
2919293900	629	93.73	323	627	4	302	1.9e-54	178.9	COG1752	Predicted acylesterase/phospholipase RssA, containd patatin domain	306
2919293901	301	97.97	12	301	4	292	4.2e-39	129.3	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2919293902	153	90.18	1	153	15	161	1.2e-60	198	COG1546	Nicotinamide mononucleotide (NMN) deamidase PncC	162
2919293903	174	96.27	10	173	6	160	1.2e-38	127.1	COG1267	Phosphatidylglycerophosphatase A	160
2919293904	162	96.86	1	150	4	157	2.2e-31	104.1	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2919293906	232	21.58	31	230	38	130	3.9e-04	13.6	COG0172	Seryl-tRNA synthetase	429
2919293908	294	98.01	5	293	1	295	9.0e-59	193.9	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919293909	351	96.88	16	335	4	314	2.5e-22	73.2	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2919293910	395	12.5	32	76	22	48	4.9e-04	5.3	COG0778	Nitroreductase	207
2919293910	395	34.72	268	394	131	205	4.9e-04	6.5	COG0778	Nitroreductase	207
2919293911	349	80.3	200	334	21	126	5.9e-24	78.1	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2919293915	438	98.64	3	438	7	440	3.1e-123	406.2	COG4097	Predicted ferric reductase	438
2919293916	183	94.62	9	181	4	179	5.4e-31	101.6	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
2919293918	324	99.38	1	323	3	320	1.1e-99	327.6	COG0611	Thiamine monophosphate kinase	317
2919293919	305	97.34	4	300	2	294	1.4e-57	189.9	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919293921	132	84.06	64	128	5	62	8.1e-21	21.3	COG1942	Phenylpyruvate tautomerase PptA, 4-oxalocrotonate tautomerase family	69
2919293921	132	91.3	1	65	1	63	8.1e-21	43.7	COG1942	Phenylpyruvate tautomerase PptA, 4-oxalocrotonate tautomerase family	69
2919293922	374	96.75	10	372	1	357	1.5e-123	406.7	COG2170	Gamma-glutamyl:cysteine ligase YbdK, ATP-grasp superfamily	369
2919293923	419	87.25	15	403	6	354	1.9e-15	50.5	COG0475	Kef-type K+ transport system, membrane component KefB	397
2919293924	672	96.45	2	672	20	672	0.0e+00	491.2	COG4389	Site-specific recombinase	677
2919293925	135	91.27	1	122	6	120	4.9e-46	150	COG2967	Uncharacterized protein affecting Mg2+/Co2+ transport	126
2919293926	226	97.27	2	226	3	216	3.0e-89	292.2	COG0036	Pentose-5-phosphate-3-epimerase	220
2919293928	733	81.73	369	732	64	385	8.1e-15	49.9	COG0642	Signal transduction histidine kinase	336
2919293929	232	98.28	2	232	2	229	2.8e-22	73.4	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
2919293930	452	20.27	311	452	185	245	4.9e-17	5.3	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
2919293930	452	75.08	62	314	7	232	4.9e-17	56.4	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
2919293932	236	95.95	13	236	3	215	2.7e-55	182	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
2919293933	549	91.76	72	512	36	425	2.4e-113	374.1	COG0840	Methyl-accepting chemotaxis protein	408
2919293935	499	98.93	19	498	2	463	0.0e+00	544.4	COG0147	Anthranilate/para-aminobenzoate synthases component I	462
2919293936	115	90.1	7	106	7	97	5.0e-20	65.7	COG1605	Chorismate mutase	101
2919293937	196	98.95	2	195	2	190	5.7e-81	264.8	COG0512	Anthranilate/para-aminobenzoate synthase component II	191
2919293938	223	98.56	4	220	2	206	2.6e-60	197.4	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
2919293939	345	98.53	2	340	4	338	0.0e+00	440.8	COG0547	Anthranilate phosphoribosyltransferase	338
2919293941	267	99.61	6	267	1	253	2.6e-97	319.3	COG0134	Indole-3-glycerol phosphate synthase	254
2919293942	238	93.69	20	238	5	212	7.2e-69	226.1	COG0692	Uracil DNA glycosylase	223
2919293944	303	97.01	9	303	6	297	1.1e-57	190.3	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919293945	327	95.92	9	325	11	316	9.2e-95	311.5	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2919293946	533	97.25	4	533	14	543	0.0e+00	572.3	COG0405	Gamma-glutamyltranspeptidase	539
2919293947	301	97.34	15	299	3	295	6.2e-32	105.3	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2919293948	381	98.85	18	379	2	346	8.1e-127	417	COG0809	S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase)	348
2919293949	321	97.42	3	315	3	304	2.8e-81	267	COG1105	Fructose-1-phosphate kinase or kinase (PfkB)	310
2919293950	426	98.86	30	373	5	352	2.2e-87	288	COG2206	HD-GYP domain, c-di-GMP phosphodiesterase class II (or its inactivated variant)	344
2919293951	719	97.64	10	712	14	675	0.0e+00	790.7	COG1200	RecG-like helicase	677
2919293952	321	97.34	1	315	1	293	8.7e-65	213.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919293953	578	97.85	90	574	8	416	4.2e-56	178.6	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
2919293954	172	98.73	15	171	3	157	1.2e-53	175.6	COG0783	DNA-binding ferritin-like protein (oxidative damage protectant)	156
2919293955	122	93.98	1	120	6	130	4.8e-19	62.4	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2919293956	374	67.26	8	372	127	391	1.0e-43	144.5	COG0642	Signal transduction histidine kinase	336
2919293957	207	54.55	2	206	154	345	5.5e-55	180.9	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
2919293958	278	97.78	10	277	5	268	1.9e-55	182.3	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
2919293959	1147	90.98	306	874	6	126	1.1e-79	65	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2919293959	1147	92.48	871	1000	6	128	1.1e-79	60.5	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2919293959	1147	93.98	1017	1147	4	128	1.1e-79	129.5	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2919293959	1147	95.65	10	215	6	203	1.5e-35	116.9	COG5278	Extracellular (periplasmic) sensor domain CHASE3 (specificity unknown)	207
2919293960	297	97.24	5	290	8	289	2.2e-78	257.5	COG0382	4-hydroxybenzoate polyprenyltransferase	289
2919293961	278	98.88	11	275	3	267	3.0e-88	290	COG0345	Pyrroline-5-carboxylate reductase	266
2919293962	497	98	1	497	6	496	0.0e+00	718.2	COG0554	Glycerol kinase	499
2919293963	254	98.43	1	254	3	252	3.9e-81	266.7	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
2919293964	363	98.86	1	346	3	348	4.4e-89	293.5	COG3839	ABC-type sugar transport system, ATPase component	338
2919293965	358	94.86	1	354	16	347	4.9e-96	316.3	COG3839	ABC-type sugar transport system, ATPase component	338
2919293966	298	95.97	1	291	7	292	2.7e-64	211.6	COG1175	ABC-type sugar transport system, permease component	295
2919293967	270	94.35	3	270	16	282	1.1e-73	242.3	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
2919293968	102	93.81	1	102	6	96	1.5e-33	105.4	COG5477	Predicted small integral membrane protein	97
2919293969	577	99.1	1	520	4	442	1.2e-68	226.7	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
2919293970	530	96.46	12	522	2	519	0.0e+00	512.9	COG0578	Glycerol-3-phosphate dehydrogenase	532
2919293971	122	100	1	122	1	123	2.8e-56	183.2	COG0093	Ribosomal protein L14	122
2919293972	106	97.22	1	104	3	107	1.2e-28	93.9	COG0198	Ribosomal protein L24	104
2919293973	179	99.44	1	179	1	179	2.7e-78	256.1	COG0094	Ribosomal protein L5	180
2919293974	101	95.08	41	101	4	61	1.6e-25	82.7	COG0199	Ribosomal protein S14	61
2919293975	131	99.25	1	131	1	132	5.4e-53	172.7	COG0096	Ribosomal protein S8	132
2919293976	177	98.88	1	177	1	177	9.6e-66	215.1	COG0097	Ribosomal protein L6P/L9E	178
2919293977	121	96.03	1	121	6	126	3.9e-35	115.5	COG0256	Ribosomal protein L18	125
2919293978	172	88.59	2	172	19	181	9.4e-69	224.6	COG0098	Ribosomal protein S5	181
2919293979	60	96.36	7	60	1	53	6.0e-25	81.1	COG1841	Ribosomal protein L30/L7E	55
2919293980	143	97.4	1	143	1	150	3.7e-44	144.9	COG0200	Ribosomal protein L15	152
2919293981	439	96.82	2	432	10	435	0.0e+00	524.8	COG0201	Preprotein translocase subunit SecY	436
2919293982	37	100	1	37	1	38	8.3e-23	72.1	COG0257	Ribosomal protein L36	38
2919293983	121	97.52	1	121	1	118	2.6e-51	167.4	COG0099	Ribosomal protein S13	121
2919293984	134	96.92	1	134	5	130	1.8e-57	187.7	COG0100	Ribosomal protein S11	129
2919293985	207	99.52	1	207	2	210	6.2e-65	213.1	COG0522	Ribosomal protein S4 or related protein	205
2919293986	330	98.43	5	329	2	315	3.4e-119	391.9	COG0202	DNA-directed RNA polymerase, alpha subunit/40 kD subunit	317
2919293987	130	100	1	116	1	116	6.2e-53	172.2	COG0203	Ribosomal protein L17	116
2919293989	298	93.02	1	295	1	280	1.2e-41	137.7	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919293990	182	91.33	1	148	1	137	3.2e-39	128.6	COG1959	DNA-binding transcriptional regulator, IscR family	150
2919293991	197	97.56	1	197	5	204	1.1e-57	189	COG2095	Small neutral amino acid transporter SnatA, MarC family	203
2919293992	137	97.83	1	137	3	137	2.2e-65	213.2	COG3565	Predicted dioxygenase of extradiol dioxygenase family	138
2919293993	124	27.2	2	116	135	230	4.5e-08	26.7	COG1537	Stalled ribosome rescue protein Dom34, pelota family	352
2919293994	123	95	1	122	1	114	4.7e-28	92.3	COG1734	RNA polymerase-binding transcription factor DksA	120
2919293995	215	96.74	2	207	1	208	1.3e-32	107.6	COG0625	Glutathione S-transferase	211
2919293997	778	93.84	4	768	17	762	3.2e-53	175.7	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
2919293998	186	96.63	3	182	2	173	1.6e-42	139.6	COG4549	Uncharacterized protein YcnI	178
2919293999	161	88.96	1	161	5	141	7.5e-46	150	COG2847	Copper(I)-binding protein	151
2919294001	444	17.22	368	440	321	387	1.6e-31	41.7	COG4398	Small ligand-binding sensory domain FIST	389
2919294001	444	78.41	4	351	13	317	1.6e-31	66.2	COG4398	Small ligand-binding sensory domain FIST	389
2919294002	441	98.4	1	434	6	436	1.2e-125	413.9	COG1253	Hemolysin or related protein, contains CBS domains	429
2919294003	391	92.98	271	391	7	112	1.9e-15	49.3	COG0607	Rhodanese-related sulfurtransferase	110
2919294004	404	95.5	6	365	4	279	1.7e-51	169.1	COG2041	Periplasmic DMSO/TMAO reductase YedYZ, molybdopterin-dependent catalytic subunit	271
2919294005	112	67.68	1	112	33	143	6.7e-16	53.4	COG2010	Cytochrome c, mono- and diheme variants	150
2919294006	438	95.36	1	429	5	374	7.4e-68	223.2	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
2919294008	260	93.94	5	260	11	258	1.0e-29	97.6	COG3971	2-keto-4-pentenoate hydratase	264
2919294012	443	63.09	4	385	35	357	5.4e-72	237.3	COG0661	Predicted unusual protein kinase regulating ubiquinone biosynthesis, AarF/ABC1/UbiB family	517
2919294014	299	95.22	1	206	7	205	1.5e-27	91.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2919294015	243	78.08	8	73	13	69	2.3e-07	24.1	COG3655	DNA-binding transcriptional regulator, XRE family	73
2919294017	650	70.88	411	636	9	193	2.3e-43	141.9	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
2919294020	338	99.38	1	335	1	321	0.0e+00	430.7	COG2515	1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase, PLP-dependent ACC family	323
2919294021	171	97.47	16	169	4	157	2.9e-36	119.1	COG1522	DNA-binding transcriptional regulator, Lrp family	154
2919294022	304	96.35	2	294	6	295	2.6e-40	132.8	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2919294023	393	98.17	1	393	5	379	3.1e-83	274.3	COG3268	Uncharacterized conserved protein, related to short-chain dehydrogenases	382
2919294024	162	68.75	2	76	10	75	3.1e-24	41.7	COG4298	Uncharacterized protein	95
2919294024	162	76.04	72	155	12	84	3.1e-24	37.6	COG4298	Uncharacterized protein	95
2919294026	229	74.56	1	228	49	262	1.1e-55	182.9	COG4727	Uncharacterized protein	287
2919294027	350	12.93	183	300	409	487	2.2e-04	10	COG4232	Thiol:disulfide interchange protein	569
2919294027	350	17.35	13	179	33	138	2.2e-04	6	COG4232	Thiol:disulfide interchange protein	569
2919294028	469	94.54	287	469	10	182	3.2e-53	174.3	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2919294029	189	73.75	120	188	17	75	9.7e-21	67	COG2771	DNA-binding transcriptional regulator, CsgD family	65
2919294030	380	94.54	201	375	10	182	1.7e-48	158.9	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
2919294032	390	96.51	6	390	5	363	0.0e+00	526.5	COG0343	Queuine/archaeosine tRNA-ribosyltransferase	372
2919294033	159	94.34	1	143	7	156	2.6e-22	74.4	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
2919294035	411	68.45	159	411	99	315	1.2e-56	186.4	COG2829	Outer membrane phospholipase A	317
2919294037	699	99.25	3	672	2	667	0.0e+00	627.9	COG0210	Superfamily I DNA or RNA helicase	655
2919294038	429	87.98	28	417	9	330	6.3e-56	184.1	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2919294039	317	96.49	2	317	8	309	1.8e-47	156.1	COG0679	Predicted permease	311
2919294040	93	43.51	6	73	45	101	4.4e-09	30.4	COG1917	Cupin domain protein related to quercetin dioxygenase	131
2919294041	653	97.61	57	650	13	544	0.0e+00	542.4	COG0405	Gamma-glutamyltranspeptidase	539
2919294042	710	14.58	3	126	3	109	0.0e+00	42.4	COG1198	Primosomal protein N' (replication factor Y) - superfamily II helicase	730
2919294042	710	72.89	115	710	199	733	0.0e+00	605.5	COG1198	Primosomal protein N' (replication factor Y) - superfamily II helicase	730
2919294043	167	76.8	2	167	15	163	4.3e-82	268.2	COG0377	NADH:ubiquinone oxidoreductase 20 kD subunit (chhain B) or related Fe-S oxidoreductase	194
2919294044	294	64.39	134	287	40	124	2.0e-12	41.1	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2919294045	370	98.3	1	367	5	351	1.4e-127	419.9	COG0407	Uroporphyrinogen-III decarboxylase	352
2919294046	526	52.48	216	449	8	208	4.2e-16	14.1	COG0477	MFS family permease	338
2919294046	526	54.57	7	232	4	212	4.2e-16	44.2	COG0477	MFS family permease	338
2919294047	183	85.71	24	162	15	128	2.3e-23	77	COG1846	DNA-binding transcriptional regulator, MarR family	126
2919294048	317	97.81	1	316	6	317	4.0e-71	233.9	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2919294049	442	38.93	224	429	264	453	2.7e-73	107.5	COG3119	Arylsulfatase A or related enzyme	475
2919294049	442	42.01	1	224	4	208	2.7e-73	138.5	COG3119	Arylsulfatase A or related enzyme	475
2919294050	323	87.88	200	323	10	125	6.1e-23	74.8	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2919294051	242	54.92	1	238	24	185	4.9e-14	47.2	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2919294052	300	96.01	5	295	2	290	1.6e-37	124.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919294053	327	18.75	9	74	198	245	9.8e-68	3.6	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
2919294053	327	89.84	68	319	16	245	9.8e-68	222.6	COG0861	Membrane protein TerC, possibly involved in tellurium resistance	254
2919294055	183	90.22	5	183	6	171	3.6e-22	73	COG3216	Uncharacterized conserved protein, DUF2062 family	184
2919294056	322	97.49	1	321	7	317	1.9e-74	244.9	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
2919294057	85	30.23	7	68	89	140	1.2e-03	12.5	COG5350	Predicted protein tyrosine phosphatase	172
2919294058	550	96.69	37	422	3	382	2.7e-69	228.9	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
2919294059	319	85.77	11	303	10	232	3.5e-27	89.8	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
2919294060	269	99.59	24	264	1	245	1.2e-52	172.5	COG1414	DNA-binding transcriptional regulator, IclR family	246
2919294061	440	98.83	9	438	4	425	0.0e+00	630.9	COG2873	O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent	426
2919294062	171	92.86	4	151	7	136	6.0e-45	146.2	COG1832	Predicted CoA-binding protein	140
2919294064	202	21.02	20	168	4	36	1.4e-10	32.1	COG1225	Peroxiredoxin	157
2919294066	160	80.3	8	140	1	106	2.1e-26	87	COG0789	DNA-binding transcriptional regulator, MerR family	124
2919294067	285	94.79	1	280	6	278	1.4e-90	297.3	COG0682	Prolipoprotein diacylglyceryltransferase	287
2919294068	750	69.23	208	750	185	607	6.3e-105	346.3	COG4232	Thiol:disulfide interchange protein	569
2919294069	766	12.18	119	303	127	202	3.4e-55	10.7	COG3914	Predicted O-linked N-acetylglucosamine transferase, SPINDLY family	620
2919294069	766	61.38	311	763	220	602	3.4e-55	167.3	COG3914	Predicted O-linked N-acetylglucosamine transferase, SPINDLY family	620
2919294072	250	96.71	1	250	1	235	5.9e-73	239.7	COG2872	Ser-tRNA(Ala) deacylase AlaX (editing enzyme)	241
2919294073	283	92.77	20	273	15	245	5.7e-65	213.2	COG1402	 Creatinine amidohydrolase/Fe(II)-dependent formamide hydrolase involved in riboflavin and F420 biosynthesis	250
2919294074	223	97.13	1	222	2	204	2.0e-26	85.9	COG0406	Broad specificity phosphatase PhoE	208
2919294075	327	92.77	7	327	5	325	3.4e-86	283.7	COG1171	Threonine dehydratase	347
2919294076	213	99.04	3	210	2	207	1.1e-58	192.1	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
2919294078	291	99.32	1	291	1	290	8.5e-73	239.7	COG0384	Predicted epimerase YddE/YHI9, PhzF superfamily	291
2919294079	287	99.32	1	287	1	290	1.9e-78	258.3	COG0384	Predicted epimerase YddE/YHI9, PhzF superfamily	291
2919294080	209	93.95	2	208	2	203	7.4e-46	150.9	COG0625	Glutathione S-transferase	211
2919294081	401	85.53	7	401	64	453	1.9e-127	420	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
2919294083	156	83.82	12	156	22	135	3.9e-16	53.4	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
2919294084	305	95.35	2	301	8	294	1.0e-31	104.6	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
2919294085	204	98.56	1	204	1	205	1.7e-29	96.8	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
2919294086	495	97.59	6	493	3	447	8.8e-101	331.1	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
2919294088	417	98.71	6	416	2	384	1.4e-44	147.1	COG1344	Flagellin and related hook-associated protein FlgL	360
2919294089	658	99.32	1	657	4	587	1.7e-106	351.4	COG1256	Flagellar hook-associated protein FlgK	552
2919294090	305	76.43	4	304	45	258	3.1e-57	188.3	COG1705	Flagellum-specific peptidoglycan hydrolase FlgJ	201
2919294091	380	98.36	11	380	7	365	0.0e+00	457.6	COG1706	Flagellar basal body P-ring protein FlgI	365
2919294092	240	96.54	17	237	8	230	5.1e-54	177.5	COG2063	Flagellar basal body L-ring protein FlgH	230
2919294093	260	98.87	1	260	1	262	8.2e-100	327.9	COG4786	Flagellar basal body rod protein FlgG	265
2919294094	246	100	1	245	1	251	3.6e-78	256.9	COG4787	Flagellar basal body rod protein FlgF	251
2919294095	426	99.36	1	426	3	471	4.3e-113	373.2	COG1749	Flagellar hook protein FlgE	423
2919294096	217	94.62	2	216	10	220	2.6e-47	155.4	COG1843	Flagellar hook assembly protein FlgD	222
2919294097	134	100	1	134	1	138	5.3e-51	166.7	COG1558	Flagellar basal body rod protein FlgC	137
2919294098	156	98.52	2	156	2	134	4.3e-32	103.9	COG1815	Flagellar basal body rod protein FlgB	133
2919294099	270	85.91	49	270	31	219	1.6e-38	126.9	COG1261	Flagella basal body P-ring formation protein FlgA	220
2919294100	106	67.74	14	100	30	92	4.0e-14	47.3	COG2747	Negative regulator of flagellin synthesis (anti-sigma28 factor)	93
2919294102	238	90.08	1	238	24	250	1.3e-75	248.6	COG1191	DNA-directed RNA polymerase specialized sigma subunit	247
2919294104	497	98.31	1	476	1	407	3.4e-83	274.1	COG1419	Flagellar biosynthesis GTPase FlhF	407
2919294105	693	97.27	3	690	14	691	0.0e+00	875.6	COG1298	Flagellar biosynthesis pathway, component FlhA	696
2919294106	384	98.07	1	361	4	359	1.5e-110	363.9	COG1377	Flagellar biosynthesis protein FlhB	363
2919294107	208	95.39	2	208	11	217	6.6e-53	173.6	COG3143	Chemotaxis regulator CheZ, phosphatase of CheY~P	217
2919294108	113	79.7	1	111	18	123	9.8e-26	84.5	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2919294109	310	98.89	10	280	3	269	1.4e-64	212.8	COG1360	Flagellar motor protein MotB	244
2919294110	286	98.5	1	286	3	265	3.6e-84	276.1	COG1291	Flagellar motor component MotA	266
2919294111	256	65.08	1	256	2	247	8.1e-65	213.5	COG1208	NDP-sugar pyrophosphorylase, includes eIF-2Bgamma, eIF-2Bepsilon, and LPS biosynthesis proteins	358
2919294112	355	98.75	9	337	3	319	4.5e-49	161.9	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2919294113	186	94.92	3	179	8	175	5.3e-57	186.4	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase or related enzyme	173
2919294114	413	54.12	52	302	26	176	5.6e-08	27.4	COG0500	SAM-dependent methyltransferase	257
2919294116	300	96.88	19	299	4	314	2.2e-33	105.9	COG0451	Nucleoside-diphosphate-sugar epimerase	314
2919294117	218	64.29	61	213	38	163	4.5e-12	39.9	COG1045	Serine acetyltransferase	194
2919294118	746	75.16	43	613	152	620	2.4e-99	327.4	COG3914	Predicted O-linked N-acetylglucosamine transferase, SPINDLY family	620
2919294119	496	99.48	3	496	2	387	2.1e-98	322.9	COG1344	Flagellin and related hook-associated protein FlgL	360
2919294120	496	99.74	3	496	2	388	8.3e-97	315.1	COG1344	Flagellin and related hook-associated protein FlgL	360
2919294121	477	99	1	475	4	496	2.1e-80	265.4	COG1345	Flagellar capping protein FliD	483
2919294122	149	92.42	4	140	6	127	1.1e-32	106.9	COG1516	Flagellin-specific chaperone FliS	132
2919294124	103	73.58	2	103	29	106	2.4e-24	80.1	COG1677	Flagellar hook-basal body complex protein FliE	105
2919294125	564	97.26	15	562	14	546	0.0e+00	530.5	COG1766	Flagellar biosynthesis/type III secretory pathway M-ring protein FliF/YscJ	545
2919294126	331	95.59	1	331	14	338	2.3e-109	360.1	COG1536	Flagellar motor switch protein FliG	339
2919294127	245	70.37	16	237	67	237	1.1e-30	101	COG1317	Flagellar biosynthesis/type III secretory pathway protein FliH	234
2919294128	464	98.19	6	464	7	440	0.0e+00	608.9	COG1157	Flagellar biosynthesis/type III secretory pathway ATPase	441
2919294129	149	93.92	1	147	4	142	4.1e-16	53.5	COG2882	Flagellar biosynthesis chaperone FliJ	148
2919294130	191	24.2	26	169	306	411	1.6e-10	34.9	COG3144	Flagellar hook-length control protein FliK	417
2919294131	181	8.18	158	181	147	159	2.0e-29	1.8	COG1580	Flagellar basal body-associated protein FliL	159
2919294131	181	78.62	1	137	18	142	2.0e-29	93	COG1580	Flagellar basal body-associated protein FliL	159
2919294132	334	97.3	1	328	1	324	5.1e-107	351.9	COG1868	Flagellar motor switch protein FliM	332
2919294133	146	80.14	1	133	29	141	2.3e-37	123	COG1886	Flagellar motor switch/type III secretory pathway protein FliN	136
2919294134	121	72.86	1	119	29	130	9.5e-16	52.2	COG3190	Flagellar biogenesis protein FliO	137
2919294135	234	85.14	2	233	37	248	5.4e-98	321.6	COG1338	Flagellar biosynthetic protein FliP	248
2919294136	89	98.88	1	89	1	88	8.9e-32	103.5	COG1987	Flagellar biosynthesis protein FliQ	89
2919294137	256	96.12	2	254	3	250	3.1e-63	207.8	COG1684	Flagellar biosynthesis protein FliR	258
2919294138	209	99.53	2	209	1	210	4.5e-59	193.9	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2919294139	369	65.87	38	357	129	375	8.8e-54	177.4	COG4585	Signal transduction histidine kinase	365
2919294140	131	41.03	33	129	37	100	2.2e-03	11.9	COG1720	tRNA (Thr-GGU) A37 N-methylase	156
2919294141	120	92.48	1	120	5	127	2.7e-34	112.3	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
2919294142	714	17.64	13	206	5	137	0.0e+00	92.2	COG0643	Chemotaxis protein histidine kinase CheA	716
2919294142	714	64.72	193	714	258	745	0.0e+00	585.1	COG0643	Chemotaxis protein histidine kinase CheA	716
2919294143	162	87.27	2	162	15	158	5.0e-49	160.3	COG0835	Chemotaxis signal transduction protein	165
2919294144	270	98.52	11	270	2	267	8.1e-86	281.9	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
2919294145	249	95.73	66	225	4	160	1.4e-58	191.1	COG1871	Chemotaxis receptor (MCP) glutamine deamidase CheD	164
2919294146	368	98.58	4	363	1	347	0.0e+00	437.1	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
2919294147	633	99.25	1	526	1	531	0.0e+00	566.5	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
2919294148	365	94.52	1	145	8	145	2.6e-51	167.1	COG0117	Pyrimidine deaminase domain of riboflavin biosynthesis protein RibD	146
2919294148	365	98.64	146	361	2	218	2.1e-62	204.6	COG1985	Pyrimidine reductase, riboflavin biosynthesis	218
2919294149	314	81.06	173	308	20	126	1.2e-24	80.6	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
2919294150	253	91.79	1	249	5	250	5.7e-49	161.4	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2919294151	88	100	1	87	1	89	1.1e-25	84.2	COG1937	DNA-binding transcriptional regulator, FrmR family	89
2919294152	371	100	1	369	1	366	0.0e+00	571.6	COG1062	Zn-dependent alcohol dehydrogenase	366
2919294153	290	96.91	1	289	8	321	7.6e-80	262.8	COG0627	S-formylglutathione hydrolase FrmB	316
2919294154	544	96.58	1	543	13	549	0.0e+00	493.4	COG2194	Phosphoethanolamine transferase for periplasmic glucans (OPG), alkaline phosphatase superfamily	555
2919294155	349	99.7	21	346	1	330	2.6e-86	284.2	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2919294156	289	98.34	1	288	1	296	9.7e-51	167.5	COG0583	DNA-binding transcriptional regulator, LysR family	297
2919294157	95	91.92	2	95	6	96	1.5e-23	77.2	COG2388	Predicted acetyltransferase, GNAT superfamily	99
2919294158	165	60.68	1	165	115	293	2.4e-15	51.4	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2919294159	178	42.37	52	177	3	127	1.4e-23	78.2	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2919294160	234	88.43	1	226	1	237	9.6e-42	137.7	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
2919294161	315	84.59	1	290	1	280	6.7e-80	263.1	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
2919294164	217	90.91	21	214	13	202	1.2e-20	69.3	COG1309	DNA-binding transcriptional regulator, AcrR family	201
2919294165	417	95.62	95	405	6	289	1.1e-83	275	COG1533	DNA repair photolyase	297
2919294166	400	98.3	5	399	3	407	2.3e-99	327.1	COG0004	Ammonia channel protein AmtB	409
2919294167	633	83.51	36	626	50	454	4.6e-87	286.3	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
2919294168	325	92.62	1	317	11	311	3.3e-77	254.1	COG0042	tRNA-dihydrouridine synthase	323
2919294171	134	79.01	3	121	27	154	6.6e-10	33.9	COG0454	N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)	156
2919294173	211	98.58	3	204	2	209	9.1e-53	173.2	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
2919294174	632	56.93	478	621	7	121	1.6e-12	40.5	COG4566	Two-component response regulator, FixJ family, consists of REC and HTH domains	202
2919294174	632	71.07	118	465	110	389	7.0e-51	167.9	COG0642	Signal transduction histidine kinase	336
2919294175	479	91.65	1	455	38	476	3.4e-101	332.9	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
2919294177	868	98.63	5	862	1	794	0.0e+00	1135.3	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
2919294178	160	90.65	3	159	4	129	6.1e-34	111.4	COG4968	Tfp pilus assembly protein PilE	139
2919294179	1627	25.38	345	679	33	299	3.0e-104	0	COG3419	Tfp pilus assembly protein, tip-associated adhesin PilY1	1036
2919294179	1627	68.16	833	1621	335	1051	3.0e-104	344.6	COG3419	Tfp pilus assembly protein, tip-associated adhesin PilY1	1036
2919294180	256	22.45	168	256	147	190	7.4e-27	25.6	COG4726	Tfp pilus assembly protein PilX	196
2919294180	256	50.51	13	163	9	107	7.4e-27	61.7	COG4726	Tfp pilus assembly protein PilX	196
2919294181	366	72.7	1	323	6	242	2.0e-23	76.6	COG4966	Tfp pilus assembly protein PilW	318
2919294182	213	65.45	5	177	6	113	9.7e-18	58.3	COG4967	Tfp pilus assembly protein PilV	162
2919294183	198	73.91	9	194	2	137	1.2e-24	81.5	COG4970	Tfp pilus assembly protein FimT	181
2919294185	372	92.29	1	369	9	367	4.8e-25	82.1	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
2919294186	376	95.08	13	376	7	354	1.1e-34	114.3	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
2919294187	317	95.94	3	317	11	341	8.8e-74	243	COG2070	NAD(P)H-dependent flavin oxidoreductase YrpB, nitropropane dioxygenase family	336
2919294188	596	97.24	10	459	7	394	1.8e-106	350.6	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
2919294189	34	10.69	1	34	282	315	7.9e-15	49.7	COG2025	Electron transfer flavoprotein, alpha subunit	313
2919294190	355	74.63	7	345	77	326	3.9e-28	93.1	COG0582	Integrase	309
2919294193	152	94.81	6	149	4	149	4.0e-17	56.3	COG0219	tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain	155
2919294198	264	63.48	1	145	8	120	2.0e-40	131.6	COG3617	Prophage antirepressor	176
2919294200	155	29.66	38	144	53	87	6.5e-03	10.8	COG2919	Cell division protein FtsB	117
2919294205	252	57.14	77	252	97	228	3.2e-21	70.6	COG2932	Phage repressor protein C, contains Cro/C1-type HTH and peptisase s24 domains	214
2919294206	83	66.67	1	67	5	50	3.4e-06	21.1	COG1476	DNA-binding transcriptional regulator, XRE-family HTH domain	68
2919294216	113	57.42	11	112	40	128	2.3e-18	58	COG1403	5-methylcytosine-specific restriction endonuclease McrA	146
2919294218	583	96.01	1	577	9	538	0.0e+00	499.5	COG4626	Phage terminase-like protein, large subunit, contains N-terminal HTH domain	546
2919294219	415	89.88	19	390	34	397	3.4e-48	158.4	COG4695	Phage portal protein BeeE	398
2919294220	223	77.32	4	176	21	170	1.1e-24	81.1	COG3740	Phage head maturation protease	194
2919294224	105	92.66	1	104	3	103	1.2e-24	80.7	COG5614	Bacteriophage head-tail adaptor	109
2919294239	207	52.57	18	189	8	140	2.4e-34	110.6	COG3926	Lysozyme family protein	252
2919294242	104	41.26	14	94	18	76	3.6e-04	12.1	COG5469	Predicted metal-binding protein	143
2919294243	201	62.11	16	109	33	91	1.6e-14	45.6	COG3514	Uncharacterized conserved protein, DUF4415 family	93
2919294244	96	93.41	1	90	2	86	4.9e-06	18.4	COG2026	mRNA-degrading endonuclease RelE, toxin component of the RelBE toxin-antitoxin system	90
2919294260	269	73.56	29	263	13	229	1.5e-09	28.3	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
2919294261	179	87.88	13	178	15	159	2.9e-45	145.3	COG0835	Chemotaxis signal transduction protein	165
2919294262	428	70.12	107	428	44	341	4.3e-85	278.3	COG0840	Methyl-accepting chemotaxis protein	408
2919294263	243	97.32	1	243	7	260	6.2e-87	282.7	COG2086	Electron transfer flavoprotein, alpha and beta subunits	260
2919294264	303	96.86	1	303	1	308	7.4e-103	336.1	COG2025	Electron transfer flavoprotein, alpha subunit	313
