gene_oid	gene_length	percent_identity	query_start	query_end	subj_start	subj_end	evalue	bit_score	cog_id	cog_name	cog_length
643622155	369	35.98	37	364	1	326	2.0e-83	302	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
643622156	290	32.26	8	255	1	246	7.0e-40	157	COG1414	DNA-binding transcriptional regulator, IclR family	246
643622158	763	29.53	28	743	66	762	2.0e-117	417	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
643622159	216	27.91	1	214	8	221	8.0e-33	133	COG1802	DNA-binding transcriptional regulator, GntR family	230
643622161	292	52.92	1	290	2	292	2.0e-94	339	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
643622162	346	32.84	8	342	24	359	1.0e-68	253	COG4663	TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component	363
643622163	185	39.64	13	180	8	175	7.0e-32	130	COG4665	TRAP-type mannitol/chloroaromatic compound transport system, small permease component	182
643622164	453	46.19	11	452	11	445	3.0e-97	349	COG4664	TRAP-type mannitol/chloroaromatic compound transport system, large permease component	447
643622166	135	49.62	2	132	10	140	3.0e-31	127	COG2185	Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding)	143
643622167	481	37.08	25	466	9	435	9.0e-91	327	COG1541	Phenylacetate-coenzyme A ligase PaaK, adenylate-forming domain family	438
643622168	323	42.41	10	316	6	321	4.0e-78	285	COG1703	Putative periplasmic protein kinase ArgK or related GTPase of G3E family	323
643622169	563	51.37	18	561	3	548	0.0e+00	604	COG1884	Methylmalonyl-CoA mutase, N-terminal domain/subunit	548
643622171	347	37.27	6	166	1	159	5.0e-29	122	COG0663	Carbonic anhydrase or acetyltransferase, isoleucine patch superfamily	176
643622172	191	54.1	2	182	1	178	1.0e-50	192	COG2096	Cob(I)alamin adenosyltransferase	184
643622173	314	30.17	31	309	2	296	1.0e-20	94.3	COG0583	DNA-binding transcriptional regulator, LysR family	297
643622175	154	39.86	3	148	42	187	5.0e-24	103	COG3554	Uncharacterized protein	190
643622176	346	28.99	82	346	104	379	1.0e-24	107	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
643622177	507	30.2	251	505	8	258	3.0e-25	110	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
643622178	266	45.14	5	259	1	248	1.0e-70	260	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
643622179	333	25.08	16	331	8	328	1.0e-22	101	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
643622183	178	32.37	1	171	4	175	5.0e-25	107	COG3038	Cytochrome b561	181
643622186	411	21.57	58	408	110	516	1.0e-26	114	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
643622191	149	33.09	13	147	1	139	5.0e-11	60.4	COG2259	Uncharacterized membrane protein YphA, DoxX/SURF4 family	142
643622193	324	53.82	1	311	3	311	5.0e-113	401	COG0435	Glutathionyl-hydroquinone reductase	324
643622194	276	43.85	19	273	8	266	8.0e-65	240	COG3384	Aromatic ring-opening dioxygenase, catalytic subunit, LigB family	268
643622195	191	36.68	1	176	2	199	6.0e-29	120	COG2085	Predicted dinucleotide-binding enzyme	211
643622196	298	34.78	1	294	1	293	4.0e-35	142	COG0583	DNA-binding transcriptional regulator, LysR family	297
643622199	131	50	1	103	1	103	2.0e-29	121	COG0261	Ribosomal protein L21	103
643622200	67	52.31	1	65	23	87	9.0e-20	88.3	COG0211	Ribosomal protein L27	87
643622201	183	31.14	21	179	9	175	2.0e-17	82.3	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
643622202	342	57.76	1	342	1	348	0.0e+00	460	COG0536	GTPase involved in cell partioning and DNA repair	369
643622203	374	54.2	11	374	2	368	4.0e-117	414	COG0263	Glutamate 5-kinase	369
643622204	420	53.24	6	420	1	417	0.0e+00	544	COG0014	Gamma-glutamyl phosphate reductase	417
643622205	276	31.88	76	275	4	209	1.0e-21	97	COG5385	Uncharacterized protein	214
643622206	261	38.15	6	253	36	283	7.0e-39	154	COG3176	Putative hemolysin	292
643622207	274	29.28	28	238	3	220	9.0e-19	87.7	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
643622208	206	29.56	7	205	6	206	7.0e-21	93.8	COG0352	Thiamine monophosphate synthase	211
643622209	243	40.74	1	243	1	238	2.0e-59	222	COG0565	tRNA C32,U32 (ribose-2'-O)-methylase TrmJ or a related methyltransferase	242
643622211	391	36.21	34	378	3	314	3.0e-37	149	COG1612	Heme A synthase	323
643622212	493	41.05	1	489	1	497	0.0e+00	480	COG2317	Zn-dependent carboxypeptidase, M32 family	497
643622215	261	36.26	1	260	3	257	4.0e-42	164	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
643622216	141	31.21	1	139	1	140	1.0e-17	82	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
643622217	119	25.45	12	119	16	125	1.0e-11	61.9	COG1664	Cytoskeletal protein CcmA, bactofilin family	146
643622219	550	36.94	1	549	4	534	7.0e-107	381	COG1574	Predicted amidohydrolase YtcJ	535
643622228	302	34.92	45	296	5	232	3.0e-19	89.7	COG2801	Transposase InsO and inactivated derivatives	232
643622229	416	42.21	10	404	1	388	3.0e-112	398	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
643622230	502	34.74	47	425	1	353	3.0e-69	256	COG0348	Polyferredoxin	386
643622231	456	30.02	13	447	5	455	7.0e-74	271	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
643622237	147	28.57	14	146	14	141	5.0e-16	77	COG3666	Transposase	161
643622240	255	37.8	4	251	1	248	7.0e-34	137	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
643622241	267	45.72	1	267	13	264	1.0e-47	183	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
643622242	283	47.1	9	277	11	285	1.0e-53	203	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
643622243	385	34.78	28	364	3	340	1.0e-66	246	COG0687	Spermidine/putrescine-binding periplasmic protein	363
643622244	360	50	2	359	1	352	2.0e-113	402	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
643622245	252	46.55	191	248	4	61	2.0e-11	63.1	COG2771	DNA-binding transcriptional regulator, CsgD family	65
643622246	555	25	1	513	1	466	6.0e-42	165	COG4529	Uncharacterized NAD(P)/FAD-binding protein YdhS	474
643622247	368	23.89	17	326	4	358	5.0e-30	125	COG1680	CubicO group peptidase, beta-lactamase class C family	390
643622249	301	34.33	7	298	1	293	3.0e-51	195	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
643622250	508	27.93	12	502	2	472	3.0e-62	232	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
643622251	218	33.52	34	214	29	205	2.0e-26	112	COG0684	Regulator of RNase E activity RraA	210
643622252	266	31.35	6	255	9	250	2.0e-36	146	COG3836	2-keto-3-deoxy-L-rhamnonate aldolase RhmA	255
643622253	282	36.96	1	271	1	271	3.0e-41	162	COG0388	Predicted amidohydrolase	274
643622254	331	40.44	1	317	2	318	3.0e-79	289	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
643622255	426	51.59	47	424	1	378	4.0e-96	345	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
643622256	169	31.85	2	158	21	177	8.0e-20	90	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
643622257	327	38.24	94	326	3	237	1.0e-43	170	COG2186	DNA-binding transcriptional regulator, FadR family	241
643622259	341	30.31	17	326	15	333	3.0e-27	116	COG3180	Uncharacterized membrane protein AbrB, regulator of aidB expression	352
643622260	245	43.25	1	241	1	249	1.0e-30	126	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
643622261	417	27.74	6	405	44	442	2.0e-40	160	COG2079	2-methylcitrate dehydratase PrpD	453
643622263	246	34.35	5	233	1	229	9.0e-29	120	COG1802	DNA-binding transcriptional regulator, GntR family	230
643622265	168	33.92	1	167	7	175	5.0e-25	107	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
643622266	238	28.33	7	236	12	240	2.0e-21	96.2	COG5343	Anti-sigma-K factor RskA	240
643622267	233	34.63	1	230	1	224	1.0e-28	120	COG1802	DNA-binding transcriptional regulator, GntR family	230
643622268	322	45.02	11	318	3	313	2.0e-71	262	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
643622269	297	47.62	24	294	16	288	6.0e-60	224	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
643622270	323	47.02	4	318	1	314	1.0e-102	366	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
643622271	333	40.92	12	326	1	316	2.0e-85	309	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
643622272	519	26.23	1	492	1	525	6.0e-56	212	COG0747	ABC-type transport system, periplasmic component	556
643622273	425	21.99	69	408	61	390	2.0e-12	67.5	COG2814	Predicted arabinose efflux permease, MFS family	394
643622274	667	32.28	19	555	22	559	1.0e-84	308	COG2936	Predicted acyl esterase	563
643622275	816	31.93	553	669	1	115	4.0e-15	77.2	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
643622276	232	40.43	5	232	1	227	2.0e-53	202	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
643622277	392	53.26	2	185	1	183	8.0e-66	244	COG3005	Tetraheme cytochrome c subunit of nitrate or TMAO reductase	190
643622278	226	22.75	23	207	9	191	1.0e-15	76.6	COG3381	Cytoplasmic chaperone TorD involved in molybdoenzyme TorA maturation	204
643622279	819	33.33	9	804	1	765	0.0e+00	521	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
643622280	410	45.71	8	398	4	394	2.0e-88	319	COG0303	Molybdopterin biosynthesis enzyme	404
643622281	338	47.75	8	338	1	322	1.0e-100	359	COG2896	Molybdenum cofactor biosynthesis enzyme MoaA	322
643622282	659	52.88	21	659	2	615	0.0e+00	708	COG3211	Secreted phosphatase, PhoX family	616
643622284	292	27.89	10	286	3	296	3.0e-20	92.8	COG0583	DNA-binding transcriptional regulator, LysR family	297
643622285	309	36.03	4	127	2	137	5.0e-06	45.2	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
643622286	205	43.37	10	203	8	203	1.0e-42	166	COG0400	Predicted esterase	207
643622288	139	30.1	36	138	25	125	6.0e-06	43.4	COG1846	DNA-binding transcriptional regulator, MarR family	126
643622289	644	20.03	11	644	30	768	1.0e-19	91.9	COG1629	Outer membrane receptor proteins, mostly Fe transport	768
643622291	357	50	15	348	5	335	3.0e-116	412	COG4175	ABC-type proline/glycine betaine transport system, ATPase component	386
643622292	296	47.26	6	296	1	290	6.0e-88	317	COG4176	ABC-type proline/glycine betaine transport system, permease component	290
643622293	333	29.22	1	329	1	302	1.0e-54	207	COG2113	ABC-type proline/glycine betaine transport system, periplasmic component	302
643622295	218	36.78	54	215	9	175	3.0e-26	111	COG1045	Serine acetyltransferase	194
643622297	239	34.68	9	238	4	248	1.0e-32	133	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
643622298	446	28.4	8	442	17	515	2.0e-50	193	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
643622299	260	37.05	7	256	2	252	1.0e-50	193	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
643622300	377	20.62	10	363	14	397	5.0e-07	49.1	COG0738	Fucose permease	422
643622302	240	28.19	23	238	10	236	3.0e-22	98.6	COG3904	Predicted periplasmic protein	245
643622303	185	42.08	3	183	2	178	8.0e-33	133	COG0431	NAD(P)H-dependent FMN reductase	184
643622305	403	55.99	1	403	18	422	7.0e-115	407	COG2379	Glycerate-2-kinase	422
643622307	429	30.05	23	429	20	397	2.0e-70	260	COG2133	Glucose/arabinose dehydrogenase, beta-propeller fold	399
643622309	598	56.69	2	598	24	574	0.0e+00	790	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
643622311	415	27.57	191	415	62	313	3.0e-29	123	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
643622312	311	45.87	12	307	18	318	9.0e-76	277	COG4301	Uncharacterized conserved protein, contains predicted SAM-dependent methyltransferase domain	321
643622313	508	52.06	1	505	2	505	0.0e+00	605	COG3046	Uncharacterized protein related to deoxyribodipyrimidine photolyase	505
643622314	94	46.74	3	93	4	94	2.0e-19	87.4	COG3553	Uncharacterized protein	96
643622315	297	47.33	19	295	40	320	3.0e-75	275	COG4607	ABC-type enterochelin transport system, periplasmic component	320
643622316	551	45.36	49	551	10	500	0.0e+00	466	COG1292	Choline-glycine betaine transporter	537
643622318	407	50.25	9	402	7	376	3.0e-114	405	COG0641	Sulfatase maturation enzyme AslB, radical SAM superfamily	378
643622320	567	43.74	1	567	3	563	0.0e+00	494	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
643622322	561	30.39	132	500	1	408	3.0e-31	130	COG0840	Methyl-accepting chemotaxis protein	408
643622323	549	35.1	20	548	5	548	1.0e-128	453	COG2194	Phosphoethanolamine transferase for periplasmic glucans (OPG), alkaline phosphatase superfamily	555
643622324	126	36.44	9	125	1	118	1.0e-15	75.6	COG0818	Diacylglycerol kinase	123
643622325	438	27.36	133	417	21	315	3.0e-25	110	COG0642	Signal transduction histidine kinase	336
643622326	219	45.85	1	219	1	228	7.0e-53	200	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
643622327	130	38.93	1	122	1	131	1.0e-26	112	COG3791	Uncharacterized conserved protein	133
643622328	112	58.04	3	110	1	112	1.0e-37	147	COG2824	Uncharacterized Zn-ribbon-containing protein	112
643622330	192	37.36	1	165	1	165	2.0e-22	99	COG3416	Uncharacterized protein	233
643622331	237	45.54	15	234	12	227	4.0e-36	145	COG0670	Integral membrane protein, interacts with FtsH	233
643622332	251	24.8	2	244	7	251	3.0e-14	72	COG5662	Transmembrane transcriptional regulator (anti-sigma factor RsiW)	256
643622333	176	44.16	14	162	28	181	3.0e-20	91.3	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
643622335	825	41.41	15	563	2	553	0.0e+00	475	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
643622336	234	33.78	17	232	2	223	2.0e-36	145	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
643622337	170	27.59	12	144	11	148	1.0e-06	46	COG1981	Uncharacterized membrane protein	149
643622343	394	39.34	1	389	1	350	1.0e-79	290	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
643622344	731	30.8	316	530	8	231	2.0e-09	58.4	COG2202	PAS domain	232
643622344	731	32.06	523	722	8	215	3.0e-38	154	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
643622345	324	37.08	1	324	1	294	5.0e-57	215	COG1230	Co/Zn/Cd efflux system component	296
643622346	90	41.57	1	89	1	89	8.0e-16	75.3	COG1937	DNA-binding transcriptional regulator, FrmR family	89
643622347	572	31.23	164	505	28	408	3.0e-36	147	COG0840	Methyl-accepting chemotaxis protein	408
643622348	154	36.94	29	138	1	111	2.0e-11	61.9	COG1846	DNA-binding transcriptional regulator, MarR family	126
643622349	232	26.42	16	223	1	211	5.0e-25	107	COG0625	Glutathione S-transferase	211
643622350	232	32.37	26	224	14	211	1.0e-17	83.3	COG0625	Glutathione S-transferase	211
643622351	158	51.92	1	153	1	151	9.0e-49	185	COG3865	Glyoxalase superfamily enzyme, possibly 3-demethylubiquinone-9 3-methyltransferase	151
643622352	535	32.87	100	521	5	387	4.0e-44	172	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
643622353	342	42.27	1	333	1	343	7.0e-89	320	COG4307	Uncharacterized protein	349
643622354	84	46.99	1	82	1	82	1.0e-06	45	COG2261	Uncharacterized membrane protein YeaQ/YmgE, transglycosylase-associated protein family	82
643622355	389	25.96	29	367	7	343	5.0e-37	148	COG0628	Predicted PurR-regulated permease PerM	355
643622358	232	59.07	42	232	1	193	3.0e-71	261	COG3443	Periplasmic Zn/Cd-binding protein ZinT	193
643622359	469	39.07	16	463	1	470	6.0e-90	324	COG4529	Uncharacterized NAD(P)/FAD-binding protein YdhS	474
643622360	195	38.55	5	178	2	179	2.0e-35	142	COG3545	Predicted esterase of the alpha/beta hydrolase fold	181
643622364	438	25.81	127	432	62	363	2.0e-29	124	COG4585	Signal transduction histidine kinase	365
643622365	220	46.15	11	217	2	207	3.0e-48	185	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
643622371	289	34.93	13	287	17	307	5.0e-51	194	COG3386	Sugar lactone lactonase YvrE	307
643622372	155	51.02	7	153	10	152	8.0e-37	146	COG4329	Uncharacterized membrane protein	160
643622374	97	47.25	3	93	8	98	2.0e-20	90.3	COG3162	Uncharacterized membrane protein, DUF485 family	102
643622375	576	52.75	36	567	1	528	0.0e+00	490	COG4147	Na+(or H+)/acetate symporter ActP	529
643622377	332	37.85	12	332	13	334	4.0e-53	201	COG2855	Uncharacterized membrane protein YadS	334
643622378	197	32.53	3	165	24	179	3.0e-22	98.4	COG1838	Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain	184
643622379	320	33.01	1	298	4	297	2.0e-51	196	COG1951	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain	297
643622380	587	37.5	6	565	2	562	9.0e-98	351	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
643622383	242	38.53	7	237	4	231	1.0e-50	193	COG0479	Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit	234
643622384	330	27.3	1	318	2	311	6.0e-24	105	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
643622385	335	27.54	11	333	14	331	6.0e-23	101	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
643622386	300	32.27	50	299	12	258	8.0e-40	157	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
643622387	252	45.2	1	243	3	245	6.0e-76	277	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
643622388	553	30.39	14	538	4	536	1.0e-85	310	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
643622389	298	27.89	1	289	1	292	8.0e-31	127	COG0583	DNA-binding transcriptional regulator, LysR family	297
643622391	374	27.62	163	371	75	282	2.0e-13	69.9	COG0842	ABC-type multidrug transport system, permease component	286
643622392	901	43.83	264	496	1	235	2.0e-71	264	COG1131	ABC-type multidrug transport system, ATPase component	293
643622395	847	32.06	19	297	22	308	4.0e-27	117	COG0392	Uncharacterized membrane protein YbhN, UPF0104 family	322
643622395	847	44.32	320	847	11	538	0.0e+00	468	COG2898	Lysylphosphatidylglycerol synthetase, C-terminal domain, DUF2156 family	538
643622397	528	21.58	3	525	14	536	2.0e-22	100	COG2303	Choline dehydrogenase or related flavoprotein	542
643622399	711	28.07	1	706	2	720	8.0e-88	318	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
643622400	152	56.86	1	151	3	155	7.0e-57	212	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
643622401	247	29.65	10	235	11	226	4.0e-28	118	COG1802	DNA-binding transcriptional regulator, GntR family	230
643622402	281	37.5	21	276	8	258	5.0e-44	171	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
643622403	271	48.61	18	268	1	244	5.0e-78	284	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
643622404	343	23.33	4	327	1	315	8.0e-18	84.9	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
643622405	232	39.52	23	229	57	264	4.0e-59	220	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
643622406	203	40.62	10	201	17	207	6.0e-37	147	COG0684	Regulator of RNase E activity RraA	210
643622407	288	37.54	6	283	3	283	1.0e-43	170	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
643622408	277	32.46	10	270	4	252	2.0e-09	56.6	COG0730	Uncharacterized membrane protein YfcA	258
643622409	499	28.89	1	455	10	494	2.0e-61	230	COG1953	Cytosine/uracil/thiamine/allantoin permease	497
643622410	141	49.24	1	132	1	132	2.0e-36	145	COG3607	Predicted lactoylglutathione lyase	133
643622411	262	58.27	4	257	3	256	1.0e-99	356	COG0623	Enoyl-[acyl-carrier-protein] reductase (NADH)	259
643622412	409	45.78	1	408	2	412	3.0e-116	412	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
643622413	169	29.68	13	165	1	144	2.0e-33	135	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
643622414	147	29.84	22	143	12	133	2.0e-17	81.9	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
643622415	270	28.67	1	253	11	289	2.0e-26	112	COG1305	Transglutaminase-like enzyme, putative cysteine protease	319
643622416	393	37.4	13	386	2	389	2.0e-75	276	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
643622417	377	44.13	1	374	2	384	4.0e-81	295	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
643622418	253	39.54	1	249	1	251	1.0e-26	113	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
643622419	386	42.57	4	383	2	388	5.0e-67	248	COG0183	Acetyl-CoA acetyltransferase	392
643622420	464	46.22	32	458	1	435	1.0e-130	460	COG1797	Cobyrinic acid a,c-diamide synthase	451
643622423	531	46.78	13	526	17	530	0.0e+00	525	COG3131	Periplasmic glucans biosynthesis protein	534
643622424	344	33.33	2	318	21	335	3.0e-49	189	COG1477	Thiamine biosynthesis lipoprotein ApbE	337
643622425	165	24	16	163	1	150	6.0e-09	53.7	COG3086	Positive regulator of sigma E activity	150
643622427	95	35	14	93	16	95	4.0e-11	59.7	COG0633	Ferredoxin	102
643622428	421	37.24	10	401	5	387	2.0e-97	349	COG0426	Flavorubredoxin	388
643622429	193	64.06	1	192	1	192	7.0e-59	220	COG4657	Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfA subunit	193
643622430	188	42.05	1	175	4	179	2.0e-39	155	COG2878	Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit	198
643622431	517	43.9	19	509	7	484	2.0e-123	436	COG4656	Na+-translocating ferredoxin:NAD+ oxidoreductase  RNF, RnfC subunit	529
643622432	362	41.23	6	343	4	335	3.0e-72	265	COG4658	Na+-translocating ferredoxin:NAD+ oxidoreductase  RNF, RnfD subunit	338
643622433	219	43.62	25	209	8	195	1.0e-44	173	COG4659	Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfG subunit	195
643622434	244	51.69	6	212	5	211	3.0e-62	232	COG4660	Na+-translocating ferredoxin:NAD+ oxidoreductase  RNF, RnfE subunit	212
643622435	85	46.99	3	85	6	88	9.0e-17	78.4	COG2914	Putative antitoxin component PasI (RatB) of the RatAB toxin-antitoxin module, ubiquitin-RnfH superfamily	99
643622437	414	21.05	5	412	7	415	5.0e-39	155	COG0443	Molecular chaperone DnaK (HSP70)	579
643622438	339	48.17	1	325	1	314	1.0e-86	313	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
643622439	303	38.02	176	296	7	127	3.0e-22	99.2	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
643622441	336	43.25	9	333	3	328	3.0e-80	292	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
643622442	173	55.42	1	165	2	152	8.0e-51	193	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
643622443	327	39.1	1	327	1	284	1.0e-58	220	COG1319	CO or xanthine dehydrogenase, FAD-binding subunit	284
643622444	739	35.63	19	734	1	729	0.0e+00	474	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
643622445	256	30.34	3	249	1	261	1.0e-37	150	COG5266	Uncharacterized conserved protein, contains GH25 family domain	264
643622446	205	32.2	1	199	1	203	4.0e-15	74.9	COG0310	ABC-type Co2+ transport system, permease component	204
643622448	236	29.06	6	233	17	248	7.0e-17	80.8	COG0619	Energy-coupling factor transporter transmembrane protein EcfT	252
643622449	262	41.23	6	224	1	228	9.0e-53	200	COG1122	Energy-coupling factor transporter ATP-binding protein EcfA2	235
643622450	335	45.59	6	335	7	345	3.0e-76	279	COG1294	Cytochrome bd-type quinol oxidase, subunit 2	346
643622451	465	49.66	1	438	1	443	0.0e+00	460	COG1271	Cytochrome bd-type quinol oxidase, subunit 1	457
643622454	500	35.54	20	497	4	441	3.0e-60	226	COG3182	Uncharacterized iron-regulated membrane protein	442
643622457	1126	24.84	372	1123	201	984	3.0e-36	148	COG4717	Uncharacterized protein YhaN	984
643622458	418	24.75	5	382	3	390	1.0e-31	131	COG0420	DNA repair exonuclease SbcCD nuclease subunit	390
643622459	230	29.11	19	224	1	207	1.0e-24	106	COG0778	Nitroreductase	207
643622461	699	32.19	348	696	1	335	4.0e-40	159	COG0642	Signal transduction histidine kinase	336
643622462	315	49.05	1	315	5	319	1.0e-81	296	COG4606	ABC-type enterochelin transport system, permease component	321
643622463	306	44.77	1	306	12	316	2.0e-66	246	COG4605	ABC-type enterochelin transport system, permease component	316
643622464	252	47.41	1	251	1	251	5.0e-85	307	COG4604	ABC-type enterochelin transport system, ATPase component	252
643622465	698	38.94	33	698	8	699	0.0e+00	571	COG4771	Outer membrane receptor for ferrienterochelin and colicins	699
643622466	541	31.34	314	523	1	215	2.0e-37	150	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
643622467	230	46.22	1	230	12	248	2.0e-65	242	COG0846	NAD-dependent protein deacetylase, SIR2 family	250
643622468	345	46.11	6	344	20	365	2.0e-99	355	COG1509	L-lysine 2,3-aminomutase (EF-P beta-lysylation pathway)	369
643622469	131	56.25	4	131	15	142	2.0e-41	161	COG4101	Uncharacterized protein, RmlC-like cupin domain	142
643622470	413	46.65	4	342	2	340	1.0e-82	300	COG2951	Membrane-bound lytic murein transglycosylase B	343
643622472	532	36.87	3	532	21	554	6.0e-99	355	COG0747	ABC-type transport system, periplasmic component	556
643622473	335	47.76	1	335	1	316	5.0e-92	331	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
643622474	300	55.75	14	299	7	288	9.0e-80	290	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
643622475	282	58.74	3	269	1	267	6.0e-105	374	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
643622477	131	23.02	3	125	2	138	2.0e-07	48.3	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
643622479	464	27.61	140	462	9	329	2.0e-33	137	COG0642	Signal transduction histidine kinase	336
643622480	228	48.68	5	228	1	227	6.0e-57	214	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
643622481	474	43.75	3	368	4	347	6.0e-70	258	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
643622484	400	20.52	27	384	49	431	1.0e-13	71.4	COG2271	Sugar phosphate permease	448
643622485	516	23.87	2	312	32	360	2.0e-21	97.3	COG1680	CubicO group peptidase, beta-lactamase class C family	390
643622486	503	31.69	1	503	6	553	1.0e-83	304	COG0747	ABC-type transport system, periplasmic component	556
643622487	557	51.67	1	536	3	539	0.0e+00	610	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
643622488	275	49.81	10	274	19	285	7.0e-60	224	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
643622489	312	45.37	5	312	3	315	7.0e-80	290	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
643622490	592	58.15	18	551	2	538	0.0e+00	668	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
643622491	319	46.65	7	319	2	299	2.0e-92	332	COG2421	Acetamidase/formamidase	305
643622492	540	34.57	4	511	12	528	4.0e-84	306	COG0747	ABC-type transport system, periplasmic component	556
643622493	306	46.67	1	305	1	315	1.0e-88	319	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
643622494	295	52.5	16	294	14	289	1.0e-69	256	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
643622495	199	26.67	17	192	15	194	3.0e-26	111	COG3707	Two-component response regulator, AmiR/NasT family, consists of REC and RNA-binding antiterminator (ANTAR) domains	194
643622496	353	23.43	5	321	11	355	1.0e-29	124	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
643622497	461	45.83	5	456	1	449	0.0e+00	509	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
643622498	143	28.47	10	143	1	135	3.0e-18	84.2	COG0824	Acyl-CoA thioesterase FadM	137
643622499	179	43.17	40	178	18	156	4.0e-30	124	COG4454	Uncharacterized copper-binding protein, cupredoxin-like subfamily	158
643622500	160	26.35	1	147	1	129	5.0e-06	44.2	COG2010	Cytochrome c, mono- and diheme variants	150
643622502	331	43.87	9	312	17	322	1.0e-90	326	COG0158	Fructose-1,6-bisphosphatase	326
643622503	292	49.66	1	290	1	289	5.0e-113	400	COG3954	Phosphoribulokinase	289
643622504	657	54.61	8	657	5	662	0.0e+00	894	COG0021	Transketolase	663
643622505	333	61.14	2	330	1	331	0.0e+00	462	COG0057	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase	335
643622506	354	42.12	1	329	1	286	5.0e-95	341	COG0191	Fructose/tagatose bisphosphate aldolase	286
643622507	459	33.96	24	440	22	423	4.0e-65	242	COG1850	Ribulose 1,5-bisphosphate carboxylase, large subunit, or a RuBisCO-like protein	429
643622508	595	46.88	56	594	11	538	0.0e+00	558	COG0405	Gamma-glutamyltranspeptidase	539
643622509	253	23.01	21	246	39	253	3.0e-07	49.4	COG1682	ABC-type polysaccharide/polyol phosphate export permease	263
643622510	308	35.06	1	305	1	292	4.0e-68	251	COG1131	ABC-type multidrug transport system, ATPase component	293
643622511	323	45.4	16	321	18	326	2.0e-58	219	COG0714	MoxR-like ATPase	329
643622518	334	28.61	1	321	2	338	1.0e-38	154	COG0673	Predicted dehydrogenase	342
643622520	614	59.64	11	611	4	615	0.0e+00	802	COG3962	TPP-dependent trihydroxycyclohexane-1,2-dione (THcHDO) dehydratase, myo-inositol metabolism	617
643622521	302	28.43	4	292	1	274	3.0e-30	125	COG1082	Sugar phosphate isomerase/epimerase	274
643622524	349	56.48	1	344	1	338	1.0e-126	446	COG3839	ABC-type sugar transport system, ATPase component	338
643622525	287	37.32	13	285	10	278	5.0e-52	198	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
643622526	293	42.96	1	289	1	290	2.0e-62	232	COG1175	ABC-type sugar transport system, permease component	295
643622527	431	26.38	1	427	7	432	1.0e-48	187	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
643622528	561	43.55	1	535	1	532	1.0e-116	413	COG1283	Na+/phosphate symporter	533
643622529	533	46.13	1	533	6	541	0.0e+00	509	COG2303	Choline dehydrogenase or related flavoprotein	542
643622530	332	38.66	18	323	6	314	2.0e-44	173	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
643622531	295	45.52	12	295	6	294	8.0e-47	180	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
643622532	232	50.63	1	232	1	237	7.0e-83	300	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
643622533	257	43.2	9	254	1	250	3.0e-79	288	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
643622534	379	26.87	2	355	7	366	1.0e-45	177	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
643622535	313	28.43	4	294	1	296	1.0e-28	120	COG0583	DNA-binding transcriptional regulator, LysR family	297
643622537	337	27.59	14	283	28	297	6.0e-31	128	COG2358	TRAP-type uncharacterized transport system, periplasmic component	321
643622539	202	35.82	1	201	11	210	2.0e-43	168	COG0800	2-keto-3-deoxy-6-phosphogluconate aldolase	211
643622541	534	29.74	155	495	29	408	2.0e-32	133	COG0840	Methyl-accepting chemotaxis protein	408
643622543	395	27.92	2	389	49	431	2.0e-52	200	COG0661	Predicted unusual protein kinase regulating ubiquinone biosynthesis, AarF/ABC1/UbiB family	517
643622545	86	29.49	1	78	1	73	4.0e-07	46.5	COG3831	WGR domain, predicted DNA-binding domain in MolR	85
643622547	307	25.17	1	292	1	289	1.0e-10	61.1	COG5006	Threonine/homoserine efflux transporter RhtA	292
643622548	254	30.17	132	247	5	120	3.0e-17	82.2	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
643622549	220	38.52	2	212	11	250	3.0e-28	118	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
643622551	214	28.22	10	211	4	201	2.0e-09	56.6	COG1309	DNA-binding transcriptional regulator, AcrR family	201
643622552	1039	53.26	1	1026	2	1009	0.0e+00	996	COG0841	Multidrug efflux pump subunit AcrB	1009
643622553	387	33.69	8	373	14	372	1.0e-25	111	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
643622554	611	39.65	1	611	2	606	8.0e-128	451	COG3284	Transcriptional regulator of acetoin/glycerol metabolism	606
643622555	600	29.98	158	592	1	443	8.0e-90	325	COG2072	Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD	443
643622557	501	26.07	15	472	4	470	1.0e-29	125	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
643622558	157	40.67	5	154	3	139	3.0e-30	124	COG0394	Protein-tyrosine-phosphatase	139
643622564	584	20	113	582	54	456	6.0e-29	122	COG0471	Di- and tricarboxylate transporter	461
643622565	154	44.85	14	146	16	150	5.0e-31	127	COG4297	Uncharacterized protein YjlB	163
643622566	238	45.85	10	238	2	229	5.0e-50	191	COG1346	Putative effector of murein hydrolase	230
643622567	117	35.92	1	103	7	109	3.0e-12	63.6	COG1380	Putative effector of murein hydrolase LrgA, UPF0299 family	128
643622568	218	44.7	1	215	1	217	7.0e-40	157	COG4126	Asp/Glu/hydantoin racemase	230
643622569	278	35.93	1	268	3	267	2.0e-40	159	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
643622570	287	39.15	8	285	5	282	3.0e-48	185	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
643622571	421	19.05	1	355	1	320	2.0e-20	94	COG0687	Spermidine/putrescine-binding periplasmic protein	363
643622572	396	44.73	78	396	6	352	1.0e-93	337	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
643622573	237	38.39	20	228	19	228	2.0e-27	116	COG1802	DNA-binding transcriptional regulator, GntR family	230
643622574	145	41.84	1	141	1	141	2.0e-31	128	COG1959	DNA-binding transcriptional regulator, IscR family	150
643622575	336	47.75	48	336	4	291	8.0e-82	297	COG2962	Uncharacterized membrane protein RarD, contains two EamA domains	293
643622576	165	56.69	1	157	1	157	2.0e-54	204	COG2193	Bacterioferritin (cytochrome b1)	157
643622577	368	25.35	79	351	98	380	8.0e-18	85.1	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
643622578	490	34.5	309	473	3	173	2.0e-25	110	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
643622579	385	26.3	19	357	12	354	3.0e-23	103	COG0628	Predicted PurR-regulated permease PerM	355
643622580	908	59.52	1	866	9	842	0.0e+00	1145	COG1410	Methionine synthase I, cobalamin-binding domain	842
643622581	341	58.77	12	333	5	310	1.0e-112	400	COG0646	Methionine synthase I (cobalamin-dependent), methyltransferase domain	311
643622587	302	34.52	45	296	5	232	5.0e-18	85.4	COG2801	Transposase InsO and inactivated derivatives	232
643622588	167	34.62	12	167	11	166	3.0e-26	111	COG5465	Uncharacterized protein	166
643622589	273	45.32	11	273	4	265	5.0e-57	214	COG0345	Pyrroline-5-carboxylate reductase	266
643622590	110	35.65	1	109	10	123	1.0e-15	75	COG0073	tRNA-binding EMAP/Myf domain	123
643622591	315	43.34	1	315	3	321	1.0e-78	286	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
643622594	439	44.57	259	429	5	177	2.0e-33	137	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
643622596	452	36.64	10	441	4	465	1.0e-82	300	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
643622597	468	37.42	3	466	9	447	1.0e-102	367	COG4664	TRAP-type mannitol/chloroaromatic compound transport system, large permease component	447
643622598	190	31.84	3	181	6	182	8.0e-38	150	COG4665	TRAP-type mannitol/chloroaromatic compound transport system, small permease component	182
643622599	337	31.95	2	312	39	346	6.0e-71	261	COG4663	TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component	363
643622601	401	29.9	17	399	1	417	1.0e-31	131	COG0577	ABC-type antimicrobial peptide transport system, permease component	419
643622602	233	51.79	6	227	1	224	3.0e-80	291	COG1136	ABC-type lipoprotein export system, ATPase component	226
643622603	425	26.71	17	338	1	309	6.0e-21	95.6	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
643622604	147	54.86	3	146	1	144	5.0e-54	203	COG0757	3-dehydroquinate dehydratase	146
643622605	294	25.96	9	210	5	210	8.0e-16	77.9	COG0625	Glutathione S-transferase	211
643622609	221	30.08	1	117	10	131	2.0e-14	72.7	COG4991	Uncharacterized conserved protein YraI	155
643622610	324	41.85	5	324	3	326	3.0e-68	252	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
643622611	135	23.08	1	128	47	176	3.0e-11	61	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
643622612	268	39.74	41	268	1	216	5.0e-54	204	COG1878	Kynurenine formamidase	218
643622613	387	27.18	1	380	1	364	7.0e-45	174	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
643622614	315	32.24	1	298	1	297	3.0e-31	129	COG0583	DNA-binding transcriptional regulator, LysR family	297
643622615	318	36.05	1	316	1	317	5.0e-56	211	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
643622616	658	42.75	1	503	1	503	1.0e-106	381	COG3333	TctA family transporter	504
643622617	360	51.27	5	356	3	346	3.0e-120	424	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
643622618	357	48	7	356	5	345	2.0e-123	436	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
643622619	260	44.72	1	241	1	246	2.0e-74	272	COG1120	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	258
643622620	344	45.86	59	343	43	332	7.0e-48	184	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
643622621	334	24.26	5	328	9	312	3.0e-29	122	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
643622622	264	37.9	10	257	13	260	1.0e-45	176	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
643622623	290	40.44	22	290	11	282	1.0e-51	196	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
643622624	372	47.49	17	369	1	352	7.0e-108	384	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
643622625	365	23.71	22	358	9	354	3.0e-34	139	COG0687	Spermidine/putrescine-binding periplasmic protein	363
643622626	217	32.5	15	213	10	207	9.0e-29	120	COG0684	Regulator of RNase E activity RraA	210
643622627	263	36.47	2	262	8	263	8.0e-49	187	COG0388	Predicted amidohydrolase	274
643622628	299	29.3	4	273	1	270	2.0e-28	120	COG0583	DNA-binding transcriptional regulator, LysR family	297
643622629	556	43.43	361	530	5	178	1.0e-34	141	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
643622631	267	30.71	21	257	3	223	6.0e-19	88.3	COG1434	Uncharacterized SAM-binding protein YcdF, DUF218 family	223
643622632	340	23.41	2	329	1	404	5.0e-21	95.4	COG3395	Uncharacterized conserved protein YgbK, DUF1537 family	413
643622633	239	36.48	3	228	2	231	8.0e-38	150	COG2186	DNA-binding transcriptional regulator, FadR family	241
643622634	328	48.17	6	327	4	329	2.0e-97	349	COG1995	4-hydroxy-L-threonine phosphate dehydrogenase PdxA	332
643622635	316	39.94	1	315	3	320	1.0e-67	250	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
643622636	294	36.62	7	289	10	292	1.0e-62	233	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
643622637	498	46.46	1	490	1	495	6.0e-125	441	COG3333	TctA family transporter	504
643622638	317	38.66	3	311	6	316	4.0e-58	218	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
643622641	357	38.92	1	357	10	377	1.0e-84	307	COG1454	Alcohol dehydrogenase, class IV	377
643622642	266	55.64	5	261	2	258	1.0e-95	343	COG1120	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	258
643622643	346	44.44	20	341	21	344	1.0e-49	190	COG4779	ABC-type enterobactin transport system, permease component	346
643622644	307	48.41	28	305	50	332	5.0e-51	195	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
643622645	325	28.23	1	321	2	316	2.0e-29	123	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
643622646	694	26.01	7	690	27	744	1.0e-56	214	COG4774	Outer membrane receptor for monomeric catechols	750
643622647	306	28.33	173	291	2	121	1.0e-17	84.1	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
643622649	524	27.75	145	504	8	407	3.0e-24	106	COG0840	Methyl-accepting chemotaxis protein	408
643622652	255	49.81	1	255	1	260	4.0e-86	311	COG0708	Exonuclease III	261
643622653	217	28.71	1	175	6	196	2.0e-08	52.5	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
643622654	192	27.92	1	192	15	198	7.0e-16	77.4	COG5463	Uncharacterized conserved protein YgiB, involved in bioifilm formation, UPF0441/DUF1190 family	198
643622655	400	49.37	1	397	1	387	2.0e-122	432	COG0754	Glutathionylspermidine synthase	387
643622659	221	42.98	2	219	1	227	3.0e-52	198	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
643622660	450	26.61	125	447	8	330	2.0e-36	146	COG0642	Signal transduction histidine kinase	336
643622661	519	31.15	171	497	43	408	3.0e-29	123	COG0840	Methyl-accepting chemotaxis protein	408
643622662	157	27.82	1	132	4	136	1.0e-11	62.5	COG0864	Metal-responsive transcriptional regulator, contains CopG/Arc/MetJ DNA-binding domain	136
643622665	293	33	1	293	1	297	2.0e-30	126	COG0583	DNA-binding transcriptional regulator, LysR family	297
643622666	406	30.63	31	405	21	393	3.0e-53	202	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
643622667	141	32.09	8	141	13	128	2.0e-10	58.8	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
643622668	402	43.7	8	401	1	392	1.0e-110	393	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
643622669	261	38.31	3	257	1	250	9.0e-31	127	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
643622670	240	32.13	8	228	7	210	6.0e-29	121	COG0684	Regulator of RNase E activity RraA	210
643622671	313	36.34	1	313	3	324	4.0e-62	232	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
643622672	321	36.04	9	315	1	298	4.0e-63	235	COG2421	Acetamidase/formamidase	305
643622673	394	35.94	17	393	2	382	3.0e-72	265	COG0006	Xaa-Pro aminopeptidase	384
643622674	211	36.54	1	205	12	219	1.0e-23	103	COG1802	DNA-binding transcriptional regulator, GntR family	230
643622675	426	23.22	37	420	24	403	1.0e-22	101	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
643622676	331	40.97	1	303	4	311	2.0e-61	229	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
643622677	220	31.82	1	215	11	230	8.0e-26	110	COG1802	DNA-binding transcriptional regulator, GntR family	230
643622678	354	42.44	3	313	1	310	6.0e-78	284	COG1984	Allophanate hydrolase subunit 2	314
643622679	246	50.22	9	232	3	223	9.0e-58	217	COG2049	Allophanate hydrolase subunit 1	223
643622680	433	32.98	60	431	10	379	9.0e-63	234	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
643622681	163	23.33	1	149	10	159	4.0e-11	61	COG4665	TRAP-type mannitol/chloroaromatic compound transport system, small permease component	182
643622682	327	28.87	1	326	1	330	3.0e-40	159	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
643622683	256	52.78	3	254	2	252	2.0e-86	312	COG1540	Lactam utilization protein B (function unknown)	252
643622684	285	37.72	6	281	5	281	1.0e-56	213	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
643622685	308	30.9	10	306	6	294	8.0e-36	144	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
643622686	308	27.38	22	272	2	264	6.0e-29	121	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
643622687	242	63.9	1	241	2	240	3.0e-104	370	COG1126	ABC-type polar amino acid transport system, ATPase component	240
643622688	226	40	16	223	10	219	2.0e-32	132	COG0765	ABC-type amino acid transport system, permease component	222
643622689	221	48.1	14	221	11	220	7.0e-44	170	COG0765	ABC-type amino acid transport system, permease component	222
643622690	308	29.57	2	300	1	273	4.0e-33	135	COG0388	Predicted amidohydrolase	274
643622691	485	32.37	3	451	1	430	9.0e-80	291	COG0044	Dihydroorotase or related cyclic amidohydrolase	430
643622692	213	31.34	2	211	1	215	1.0e-25	110	COG4126	Asp/Glu/hydantoin racemase	230
643622693	309	26.58	10	306	1	297	8.0e-26	111	COG0583	DNA-binding transcriptional regulator, LysR family	297
643622694	202	31.21	13	185	7	167	3.0e-24	105	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
643622696	340	37.31	1	331	1	335	4.0e-68	251	COG5351	Uncharacterized protein	367
643622702	889	40.23	17	885	1	786	0.0e+00	734	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
643622703	668	24.58	20	288	2	294	3.0e-31	130	COG0515	Serine/threonine protein kinase	384
643622704	364	29.03	8	361	1	345	1.0e-16	81.3	COG3515	Predicted component of the type VI protein secretion system	346
643622705	176	45.98	3	176	2	169	6.0e-46	177	COG3516	Predicted component of the type VI protein secretion system	169
643622706	505	54.55	1	504	2	495	0.0e+00	691	COG3517	Predicted component of the type VI protein secretion system	495
643622707	163	26.92	1	150	1	153	2.0e-22	98.4	COG3157	Type VI protein secretion system component Hcp (secreted cytotoxin)	162
643622708	235	33.56	87	234	25	157	6.0e-15	74.6	COG3518	Predicted component of the type VI protein secretion system	157
643622709	622	39.4	2	622	1	621	0.0e+00	472	COG3519	Type VI protein secretion system component VasA	621
643622710	287	34.91	2	268	59	323	1.0e-39	156	COG3520	Predicted component of the type VI protein secretion system	335
643622711	409	33.57	2	406	5	426	8.0e-62	231	COG3456	Predicted component of the type VI protein secretion system, contains a FHA domain	430
643622712	145	30	2	144	7	156	2.0e-20	91.5	COG3521	Predicted component of the type VI protein secretion system	159
643622713	442	39.69	1	442	2	446	4.0e-101	361	COG3522	Predicted component of the type VI protein secretion system	446
643622714	453	34	20	268	6	252	7.0e-41	162	COG3455	Type VI protein secretion system component VasF	262
643622715	1173	37.88	4	1173	2	1187	0.0e+00	774	COG3523	Type VI protein secretion system component VasK	1188
643622717	767	42.64	8	540	15	547	0.0e+00	507	COG3501	Uncharacterized conserved protein, implicated in type VI secretion and phage assembly	550
643622720	248	40	19	245	12	251	1.0e-49	189	COG0631	Serine/threonine protein phosphatase PrpC	262
643622721	254	28.11	69	251	9	186	7.0e-20	91.1	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
643622724	357	24.1	59	347	86	380	3.0e-10	59.6	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
643622726	934	27.83	1	387	5	380	4.0e-29	124	COG4249	Uncharacterized protein, contains caspase domain	380
643622729	413	45.95	1	412	1	404	1.0e-117	416	COG3347	Rhamnose utilisation protein RhaD, predicted bifunctional aldolase and dehydrogenase	404
643622730	334	27.07	1	309	11	321	1.0e-39	157	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
643622731	327	41.38	1	316	2	313	6.0e-47	181	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
643622732	336	38.02	4	313	5	316	8.0e-45	174	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
643622733	491	46.57	1	483	4	498	0.0e+00	506	COG1129	ABC-type sugar transport system, ATPase component	500
643622734	325	44.87	23	324	11	321	4.0e-74	272	COG2390	DNA-binding transcriptional regulator LsrR, DeoR family	321
643622735	509	34.87	1	495	3	498	4.0e-93	335	COG1070	Sugar (pentulose or hexulose) kinase	502
643622736	102	35.11	1	94	3	96	3.0e-19	86.6	COG1359	Quinol monooxygenase YgiN	100
643622737	223	22.42	1	137	4	167	3.0e-06	45.8	COG1432	Uncharacterized conserved protein, LabA/DUF88 family	181
643622738	440	20.97	52	423	2	296	4.0e-31	129	COG2421	Acetamidase/formamidase	305
643622741	220	42.61	1	220	1	229	2.0e-51	195	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
643622742	447	25.55	143	447	15	331	1.0e-21	97.9	COG0642	Signal transduction histidine kinase	336
643622744	326	28.22	15	164	6	167	8.0e-12	64.7	COG2203	GAF domain	175
643622744	326	42.78	146	324	1	179	2.0e-37	149	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
643622745	358	38.15	25	349	1	321	3.0e-72	265	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
643622746	345	26.91	1	306	1	321	6.0e-34	138	COG0687	Spermidine/putrescine-binding periplasmic protein	363
643622747	329	49.3	1	329	3	352	3.0e-106	378	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
643622748	282	40.36	2	281	10	287	2.0e-51	196	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
643622749	261	39.29	3	254	9	260	2.0e-45	176	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
643622750	337	33.53	1	336	1	334	5.0e-67	248	COG3938	Proline racemase	341
643622751	540	45.66	5	529	1	539	0.0e+00	565	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
643622752	292	36.86	29	281	24	278	1.0e-49	190	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
643622753	311	41.29	1	307	4	313	4.0e-71	261	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
643622754	534	27.29	16	498	1	522	2.0e-73	270	COG0747	ABC-type transport system, periplasmic component	556
643622755	535	28.71	17	509	2	531	2.0e-74	273	COG0747	ABC-type transport system, periplasmic component	556
643622757	477	37.39	3	465	1	470	4.0e-95	342	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
643622758	344	38.58	28	343	23	313	2.0e-65	242	COG0123	Acetoin utilization deacetylase AcuC or a related deacetylase	340
643622759	216	24.24	14	211	1	196	2.0e-06	46.6	COG1309	DNA-binding transcriptional regulator, AcrR family	201
643622760	287	39.09	70	285	80	293	1.0e-34	140	COG2159	Predicted metal-dependent hydrolase, TIM-barrel fold	293
643622761	531	29.94	2	529	1	483	6.0e-75	275	COG1233	Phytoene dehydrogenase-related protein	487
643622762	554	34.83	18	536	1	531	5.0e-93	335	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
643622763	495	48.52	21	492	4	466	0.0e+00	465	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
643622764	467	38.26	15	456	7	447	2.0e-125	443	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
643622766	655	34.86	1	276	2	256	6.0e-36	146	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
643622766	655	44.63	292	583	5	301	5.0e-73	269	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
643622767	399	42.96	1	399	1	392	1.0e-84	307	COG0183	Acetyl-CoA acetyltransferase	392
643622768	342	58.19	1	342	2	338	7.0e-125	440	COG2130	NADPH-dependent curcumin reductase CurA	340
643622770	2626	29.9	2084	2582	22	477	2.0e-09	60.4	COG2931	Ca2+-binding protein, RTX toxin-related	510
643622777	755	31.88	3	570	100	653	3.0e-107	383	COG0209	Ribonucleotide reductase alpha subunit	696
643622779	143	49.3	5	142	3	143	1.0e-38	152	COG5458	Uncharacterized protein	144
643622781	365	31.18	4	355	18	378	1.0e-22	100	COG3705	ATP phosphoribosyltransferase regulatory subunit HisZ	390
643622782	494	32.64	13	494	5	429	2.0e-99	356	COG0124	Histidyl-tRNA synthetase	429
643622784	1163	46.35	5	1139	2	1119	0.0e+00	1188	COG0587	DNA polymerase III, alpha subunit	1139
643622786	485	52.71	1	485	6	492	0.0e+00	519	COG4630	Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A	493
643622787	825	55.7	3	825	19	776	0.0e+00	963	COG4631	Xanthine dehydrogenase, molybdopterin-binding subunit B	781
643622788	313	27.91	10	305	7	258	3.0e-23	102	COG1975	Xanthine and CO dehydrogenase maturation factor, XdhC/CoxF family	278
643622789	507	48.21	1	495	1	501	0.0e+00	580	COG3845	ABC-type uncharacterized transport system, ATPase component	501
643622790	360	41.62	3	360	2	355	1.0e-70	260	COG4603	ABC-type uncharacterized transport system, permease component	356
643622791	310	49.16	12	310	10	304	2.0e-73	269	COG1079	ABC-type uncharacterized transport system, permease component	304
643622792	364	35.09	1	335	5	343	4.0e-69	255	COG1744	Basic membrane lipoprotein Med, periplasmic binding protein (PBP1-ABC) superfamily	345
643622793	438	24	13	372	3	354	5.0e-24	106	COG1252	NADH dehydrogenase, FAD-containing subunit	405
643622794	356	30.38	1	344	3	373	3.0e-27	116	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
643622796	263	39.48	1	263	1	269	2.0e-60	226	COG3757	Lyzozyme M1 (1,4-beta-N-acetylmuramidase), GH25 family	269
643622797	833	25.74	1	398	1	382	2.0e-43	171	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
643622797	833	35.22	433	830	3	378	1.0e-83	305	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
643622798	260	43.46	1	259	9	268	8.0e-36	144	COG1108	ABC-type Mn2+/Zn2+ transport system, permease component	274
643622799	243	45.67	1	235	2	254	1.0e-71	263	COG1121	ABC-type Mn2+/Zn2+ transport system, ATPase component	254
643622800	163	37.68	24	161	5	141	5.0e-26	110	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
643622801	364	33.24	14	363	9	317	1.0e-57	217	COG4531	ABC-type Zn2+ transport system, periplasmic component/surface adhesin	318
643622802	327	33.43	4	326	1	306	9.0e-46	177	COG2017	Galactose mutarotase or related enzyme	308
643622804	523	42.18	14	517	8	491	2.0e-108	386	COG2986	Histidine ammonia-lyase	498
643622812	176	24.56	78	175	29	135	1.0e-07	50	COG0071	Molecular chaperone IbpA, HSP20 family	146
643622816	309	24.1	30	296	28	286	4.0e-16	79	COG0714	MoxR-like ATPase	329
643622817	406	63.79	3	406	1	405	0.0e+00	530	COG3748	Uncharacterized membrane protein	407
643622818	124	64.35	7	121	10	124	2.0e-42	164	COG3651	Uncharacterized conserved protein, DUF2237 family	125
643622819	412	73.35	14	407	1	391	0.0e+00	705	COG0133	Tryptophan synthase beta chain	396
643622821	212	47.37	4	212	2	206	3.0e-58	218	COG0135	Phosphoribosylanthranilate isomerase	208
643622823	93	53.85	1	91	2	91	9.0e-26	108	COG0776	Bacterial nucleoid DNA-binding protein	94
643622824	555	54.18	1	548	2	541	0.0e+00	558	COG0539	Ribosomal protein S1	541
643622825	206	46.3	1	198	3	218	2.0e-55	208	COG0283	Cytidylate kinase	222
643622826	436	44.04	5	432	9	427	4.0e-106	378	COG0128	5-enolpyruvylshikimate-3-phosphate synthase	428
643622827	251	37.12	20	239	3	224	9.0e-49	187	COG0220	tRNA G46 methylase TrmB	227
643622829	385	57.58	1	385	3	386	0.0e+00	569	COG0192	S-adenosylmethionine synthetase	388
643622830	495	37.1	10	491	14	511	6.0e-74	271	COG0815	Apolipoprotein N-acyltransferase	518
643622832	160	36.65	1	160	6	150	5.0e-30	123	COG0319	ssRNA-specific RNase YbeY, 16S rRNA maturation enzyme	153
643622833	346	50.46	16	341	5	331	6.0e-100	357	COG1702	Phosphate starvation-inducible protein PhoH, predicted ATPase	348
643622834	436	50.57	3	434	1	436	0.0e+00	522	COG0621	tRNA A37 methylthiotransferase MiaB	437
643622835	211	33.64	13	206	1	212	2.0e-19	89.2	COG2755	Lysophospholipase L1 or related esterase	216
643622836	229	55.95	1	225	2	228	2.0e-75	275	COG4181	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component	228
643622837	835	35.68	2	833	5	828	0.0e+00	539	COG3127	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component	829
643622840	366	28.57	8	365	6	389	6.0e-52	198	COG1252	NADH dehydrogenase, FAD-containing subunit	405
643622841	432	32.21	1	426	1	442	5.0e-81	295	COG1508	DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog	444
643622842	675	29.59	1	643	1	657	2.0e-76	281	COG0145	N-methylhydantoinase A/oxoprolinase/acetone carboxylase, beta subunit	674
643622848	131	46.91	50	130	4	84	7.0e-15	73	COG3750	Uncharacterized conserved protein, UPF0335 family	85
643622857	243	33.33	9	220	1	212	1.0e-26	113	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
643622862	527	45.76	1	516	16	520	2.0e-120	426	COG0459	Chaperonin GroEL (HSP60 family)	524
643622865	2770	47.63	1687	2748	1	1034	0.0e+00	1017	COG3459	Cellobiose phosphorylase	1056
643622870	68	55.88	1	68	1	67	8.0e-19	85.2	COG1278	Cold shock protein, CspA family	67
643622871	77	60.29	10	77	1	67	1.0e-20	91.4	COG1278	Cold shock protein, CspA family	67
643622878	539	23.93	4	228	1	222	5.0e-14	73.3	COG1961	Site-specific DNA recombinase related to the DNA invertase Pin	222
643622883	95	45.65	2	93	14	105	5.0e-13	65.9	COG2076	Multidrug transporter EmrE and related cation transporters	106
643622884	139	23.74	9	123	3	137	6.0e-07	46.7	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
643622887	105	40.37	1	105	25	132	2.0e-25	107	COG5649	Uncharacterized protein	132
643622893	707	24.83	10	707	26	750	5.0e-58	219	COG4774	Outer membrane receptor for monomeric catechols	750
643622894	298	22.68	56	273	66	300	4.0e-09	55.7	COG0657	Acetyl esterase/lipase	312
643622895	467	39.02	12	457	3	432	4.0e-81	295	COG3182	Uncharacterized iron-regulated membrane protein	442
643622898	302	34.92	45	296	5	232	5.0e-18	85.4	COG2801	Transposase InsO and inactivated derivatives	232
643622900	302	34.52	45	296	5	232	5.0e-18	85.4	COG2801	Transposase InsO and inactivated derivatives	232
643622906	349	27.93	2	346	8	381	3.0e-33	135	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
643622909	304	22.94	13	286	5	256	1.0e-18	87.6	COG1442	Lipopolysaccharide biosynthesis protein, LPS:glycosyltransferase	325
643622911	302	34.92	45	296	5	232	3.0e-19	89.7	COG2801	Transposase InsO and inactivated derivatives	232
643622913	270	27.66	82	256	25	212	1.0e-19	90.3	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
643622921	307	32.73	192	301	8	117	3.0e-12	66.4	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
643622925	142	26.67	1	139	1	150	4.0e-18	83.9	COG1959	DNA-binding transcriptional regulator, IscR family	150
643622928	312	40.13	9	312	1	309	2.0e-68	252	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
643622932	300	30.48	5	293	1	288	3.0e-37	149	COG0583	DNA-binding transcriptional regulator, LysR family	297
643622933	370	39.84	2	369	32	396	5.0e-77	281	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
643622935	493	40.76	10	478	12	472	4.0e-120	425	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
643622936	338	34.89	18	337	13	330	6.0e-55	208	COG2855	Uncharacterized membrane protein YadS	334
643622937	433	25.6	31	358	77	347	4.0e-19	89.7	COG2843	Poly-gamma-glutamate biosynthesis protein CapA/YwtB (capsule formation), metallophosphatase superfamily	372
643622938	327	32.92	6	327	2	319	1.0e-46	180	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
643622939	466	26.87	22	436	8	426	6.0e-58	218	COG2079	2-methylcitrate dehydratase PrpD	453
643622941	505	46.41	3	487	2	488	0.0e+00	466	COG3333	TctA family transporter	504
643622944	534	31.39	15	490	5	458	2.0e-83	303	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
643622948	226	29.38	25	183	9	166	1.0e-27	116	COG3467	Nitroimidazol reductase NimA or a related FMN-containing flavoprotein, pyridoxamine 5'-phosphate oxidase superfamily	166
643622949	243	40.62	1	188	1	185	8.0e-38	150	COG0518	GMP synthase - Glutamine amidotransferase domain	198
643622950	491	34.55	21	476	3	449	2.0e-91	330	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
643622953	461	34.07	8	457	23	448	3.0e-88	319	COG2710	Nitrogenase molybdenum-iron protein, alpha and beta chains	456
643622955	527	34.07	10	455	2	443	9.0e-95	341	COG2710	Nitrogenase molybdenum-iron protein, alpha and beta chains	456
643622956	275	65.45	2	275	1	274	8.0e-119	420	COG1348	Nitrogenase subunit NifH, an ATPase	278
643622957	516	39.73	4	504	33	550	7.0e-125	441	COG3604	Transcriptional regulator containing GAF, AAA-type ATPase, and DNA-binding Fis domains	550
643622964	332	23.99	1	332	2	334	9.0e-36	144	COG0673	Predicted dehydrogenase	342
643622965	295	27.6	22	257	19	257	1.0e-27	117	COG1082	Sugar phosphate isomerase/epimerase	274
643622966	277	38.64	19	276	18	281	5.0e-53	201	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
643622967	308	42.41	16	305	2	289	5.0e-65	241	COG1175	ABC-type sugar transport system, permease component	295
643622968	404	28.19	5	399	13	424	3.0e-37	149	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
643622969	305	32.7	5	305	1	311	3.0e-35	142	COG0657	Acetyl esterase/lipase	312
643622970	239	29.2	1	226	5	229	1.0e-22	100	COG1802	DNA-binding transcriptional regulator, GntR family	230
643622971	359	54	1	350	1	338	7.0e-123	433	COG3839	ABC-type sugar transport system, ATPase component	338
643622973	345	33.59	95	343	5	259	1.0e-38	154	COG2375	NADPH-dependent ferric siderophore reductase, contains FAD-binding and SIP domains	265
643622974	279	25.3	29	275	39	284	1.0e-19	90.4	COG0685	5,10-methylenetetrahydrofolate reductase	291
643622979	678	38.11	1	365	1	363	3.0e-93	336	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
643622985	346	41.44	2	334	1	332	2.0e-78	286	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
643622986	312	35.94	1	312	1	320	5.0e-37	148	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
643622988	334	46.82	16	327	4	315	4.0e-56	211	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
643622989	354	41.98	11	353	1	315	1.0e-93	336	COG1735	Predicted metal-dependent hydrolase, phosphotriesterase family	316
643622990	254	64.96	1	254	1	253	3.0e-109	388	COG5426	Uncharacterized membrane protein	254
643622991	292	33.23	2	291	1	308	5.0e-30	124	COG0524	Sugar or nucleoside kinase, ribokinase family	311
643622992	280	45.49	14	278	2	261	3.0e-80	291	COG0434	Predicted TIM-barrel enzyme	263
643622994	364	30.48	3	360	10	403	7.0e-44	171	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
643622995	371	52.42	1	345	1	344	3.0e-97	348	COG1118	ABC-type sulfate/molybdate transport systems, ATPase component	345
643622996	330	53.45	1	327	6	338	1.0e-124	439	COG4150	ABC-type sulfate transport system, periplasmic component	341
643622997	285	57.88	10	282	2	274	7.0e-68	250	COG0555	ABC-type sulfate transport system, permease component	274
643622998	279	57.55	2	279	1	278	2.0e-93	336	COG4208	ABC-type sulfate transport system, permease component	287
643622999	337	29	18	336	1	327	2.0e-48	186	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
643623000	349	36.6	1	337	1	341	6.0e-74	271	COG4213	ABC-type xylose transport system, periplasmic component	341
643623002	414	38.07	18	405	2	391	2.0e-82	300	COG4214	ABC-type xylose transport system, permease component	394
643623003	242	39.92	5	237	4	241	8.0e-61	227	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
643623004	530	45.64	2	527	5	527	0.0e+00	561	COG1069	Ribulose kinase	544
643623006	563	41.2	14	422	5	402	2.0e-91	330	COG1252	NADH dehydrogenase, FAD-containing subunit	405
643623007	553	33.16	149	495	23	408	3.0e-35	143	COG0840	Methyl-accepting chemotaxis protein	408
643623008	148	27.88	8	111	1	104	5.0e-19	86.8	COG1320	Multisubunit Na+/H+ antiporter, MnhG subunit	113
643623009	93	43.82	4	92	1	89	6.0e-12	62.4	COG2212	Multisubunit Na+/H+ antiporter, MnhF subunit	89
643623010	162	32.5	4	162	1	158	2.0e-27	115	COG1863	Multisubunit Na+/H+ antiporter, MnhE subunit	158
643623011	540	33.02	5	533	3	504	3.0e-43	170	COG0651	Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit	504
643623012	114	50.88	1	114	1	113	9.0e-26	108	COG1006	Multisubunit Na+/H+ antiporter, MnhC subunit	115
643623013	964	36.84	616	784	3	162	2.0e-19	92	COG2111	Multisubunit Na+/H+ antiporter, MnhB subunit	162
643623013	964	39.6	7	550	1	535	2.0e-112	400	COG1009	NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit	606
643623014	351	47.23	9	351	6	346	3.0e-98	352	COG0709	Selenophosphate synthase	346
643623016	483	24.21	11	482	2	533	2.0e-50	193	COG2303	Choline dehydrogenase or related flavoprotein	542
643623018	504	24.26	11	470	1	469	8.0e-28	118	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
643623019	317	27.18	136	317	1	192	6.0e-32	131	COG5663	Uncharacterized protein, HAD superfamily	194
643623020	383	21.11	18	341	8	359	6.0e-16	78.9	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
643623022	384	25.58	1	370	5	365	3.0e-13	69.8	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
643623023	356	28.51	124	343	1	216	6.0e-32	131	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
643623028	196	41.87	1	195	1	202	2.0e-45	175	COG1182	FMN-dependent NADH-azoreductase	202
643623030	293	29.77	48	256	4	200	4.0e-26	111	COG0625	Glutathione S-transferase	211
643623031	239	36.84	7	232	3	229	1.0e-46	180	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
643623032	348	30.42	1	307	9	299	6.0e-38	151	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
643623033	497	48.48	1	493	4	497	0.0e+00	581	COG1129	ABC-type sugar transport system, ATPase component	500
643623034	325	35.4	3	323	5	313	6.0e-48	184	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
643623035	336	39.08	12	336	1	312	5.0e-43	168	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
643623037	315	37.46	8	312	1	311	2.0e-49	189	COG0524	Sugar or nucleoside kinase, ribokinase family	311
643623038	324	33.21	51	314	2	228	1.0e-56	213	COG0274	Deoxyribose-phosphate aldolase	228
643623039	791	46.47	34	487	2	464	5.0e-126	445	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
643623040	263	32.47	1	257	2	272	2.0e-27	115	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
643623041	320	39.68	12	314	1	305	8.0e-60	224	COG0010	Arginase family enzyme	305
643623042	219	48.62	1	217	3	220	8.0e-54	203	COG0765	ABC-type amino acid transport system, permease component	222
643623043	266	54.22	6	254	1	240	7.0e-97	347	COG1126	ABC-type polar amino acid transport system, ATPase component	240
643623044	213	34.91	9	213	44	252	1.0e-32	133	COG3665	Uncharacterized conserved protein YcgI, DUF1989 family	264
643623045	392	23.81	1	389	1	378	3.0e-32	132	COG0006	Xaa-Pro aminopeptidase	384
643623046	293	29.29	7	292	1	297	7.0e-33	134	COG0583	DNA-binding transcriptional regulator, LysR family	297
643623047	407	26.42	23	407	6	384	9.0e-34	138	COG1680	CubicO group peptidase, beta-lactamase class C family	390
643623058	268	27.84	9	260	4	270	2.0e-27	116	COG0338	Site-specific DNA-adenine methylase	274
643623073	447	27.93	57	344	32	316	4.0e-35	142	COG0616	Periplasmic serine protease, ClpP class	317
643623074	497	33.13	8	482	16	491	6.0e-77	281	COG5511	Bacteriophage capsid protein	492
643623076	720	23.34	29	713	12	611	7.0e-55	209	COG5525	Phage terminase, large subunit GpA	611
643623077	218	25	29	172	7	133	4.0e-06	45	COG4220	Phage DNA packaging protein, Nu1 subunit of terminase	174
643623095	132	46.91	51	131	4	84	3.0e-15	74.2	COG3750	Uncharacterized conserved protein, UPF0335 family	85
643623103	253	25.56	5	249	17	276	2.0e-31	129	COG0863	DNA modification methylase	302
643623106	332	24.61	84	318	41	291	4.0e-13	69.1	COG4974	Site-specific recombinase XerD	300
643623112	302	34.92	45	296	5	232	4.0e-18	85.4	COG2801	Transposase InsO and inactivated derivatives	232
643623117	434	27.27	190	402	70	291	2.0e-19	90.3	COG4974	Site-specific recombinase XerD	300
643623124	685	24.72	1	431	1	400	2.0e-29	124	COG1479	Uncharacterized conserved protein, contains ParB-like and HNH nuclease domains	409
643623127	1620	43.03	1	1614	1	1518	0.0e+00	1523	COG4889	Predicted helicase	1518
643623129	293	30.9	11	179	14	187	2.0e-21	96.4	COG0847	DNA polymerase III, epsilon subunit or related 3'-5' exonuclease	243
643623134	458	19.22	159	457	1	291	1.0e-29	124	COG0863	DNA modification methylase	302
643623144	652	34.4	11	642	5	605	7.0e-117	415	COG5525	Phage terminase, large subunit GpA	611
643623146	500	33.67	9	489	15	492	1.0e-74	274	COG5511	Bacteriophage capsid protein	492
643623192	441	28.76	107	402	2	245	1.0e-28	121	COG1192	Cellulose biosynthesis protein BcsQ	259
643623195	314	40.37	1	314	2	319	2.0e-69	256	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
643623197	505	55.36	1	504	1	504	0.0e+00	572	COG3333	TctA family transporter	504
643623198	315	28.53	10	308	1	315	1.0e-37	150	COG0523	GTPase, G3E family	323
643623201	286	28.47	6	271	4	270	8.0e-31	127	COG1737	DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains	281
643623202	324	47	6	322	7	318	5.0e-96	344	COG2358	TRAP-type uncharacterized transport system, periplasmic component	321
643623204	141	29.33	1	141	4	152	5.0e-09	53.8	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
643623205	442	48.72	15	442	28	447	0.0e+00	478	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
643623206	272	28.11	15	272	7	287	4.0e-28	118	COG3246	Uncharacterized conserved protein, DUF849 family	298
643623207	335	23.65	9	333	3	313	5.0e-28	118	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
643623208	338	36.25	9	337	2	329	6.0e-67	247	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
643623209	171	31.65	11	168	2	159	4.0e-16	77.7	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
643623210	425	48.15	46	423	2	378	1.0e-80	293	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
643623212	418	32.68	13	418	35	427	8.0e-77	281	COG1850	Ribulose 1,5-bisphosphate carboxylase, large subunit, or a RuBisCO-like protein	429
643623213	407	29.72	1	400	1	413	6.0e-35	142	COG3395	Uncharacterized conserved protein YgbK, DUF1537 family	413
643623214	679	34.02	5	654	1	651	3.0e-115	409	COG0210	Superfamily I DNA or RNA helicase	655
643623218	405	38.73	11	382	1	323	1.0e-80	293	COG0523	GTPase, G3E family	323
643623220	471	36.51	232	471	1	226	1.0e-51	197	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
643623221	343	35.94	5	315	1	314	4.0e-56	212	COG0451	Nucleoside-diphosphate-sugar epimerase	314
643623223	334	25.18	1	271	3	266	5.0e-37	148	COG1442	Lipopolysaccharide biosynthesis protein, LPS:glycosyltransferase	325
643623224	490	25.11	1	460	5	473	1.0e-19	91.7	COG2244	Membrane protein involved in the export of O-antigen and teichoic acid	480
643623227	174	35.42	26	164	48	188	4.0e-15	74.2	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
643623228	339	27.57	1	324	3	333	5.0e-38	151	COG0673	Predicted dehydrogenase	342
643623229	376	48.53	2	363	1	371	9.0e-110	390	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
643623230	331	36.48	10	320	1	309	3.0e-52	199	COG0451	Nucleoside-diphosphate-sugar epimerase	314
643623231	397	41.84	1	377	5	371	2.0e-98	352	COG0399	dTDP-4-amino-4,6-dideoxygalactose transaminase	374
643623232	728	23.26	19	469	8	458	3.0e-29	124	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
643623233	371	27.61	15	360	10	381	2.0e-35	143	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
643623234	371	25	44	362	53	380	9.0e-23	101	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
643623236	417	24.92	86	408	83	411	1.0e-10	60.9	COG3307	O-antigen ligase	424
643623238	260	38.37	8	251	9	250	2.0e-52	199	COG1922	UDP-N-acetyl-D-mannosaminuronic acid transferase, WecB/TagA/CpsF family	253
643623239	349	26.1	1	339	4	306	4.0e-33	135	COG0451	Nucleoside-diphosphate-sugar epimerase	314
643623240	402	19.21	24	402	41	379	8.0e-17	82	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
643623241	253	34.62	32	239	3	205	2.0e-28	119	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
643623244	142	29.51	13	131	1	122	6.0e-07	46.8	COG1846	DNA-binding transcriptional regulator, MarR family	126
643623246	343	40.79	9	337	19	340	1.0e-61	230	COG1566	Multidrug resistance efflux pump	352
643623253	302	34.92	45	296	5	232	4.0e-18	85.4	COG2801	Transposase InsO and inactivated derivatives	232
643623255	324	27.76	4	241	61	303	1.0e-09	57.6	COG3547	Transposase	303
643623257	645	33.13	329	643	1	329	2.0e-30	128	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
643623258	287	22.1	27	286	54	314	1.0e-15	77.2	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
643623259	778	25.53	99	778	36	719	1.0e-64	241	COG4773	Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid	719
643623260	324	35.29	7	324	9	321	8.0e-48	184	COG3712	Periplasmic ferric-dicitrate binding protein FerR, regulates iron transport through sigma-19	322
643623261	165	31.88	6	162	17	176	4.0e-15	74.7	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
643623264	725	41.86	98	725	157	773	0.0e+00	516	COG4993	Glucose dehydrogenase	773
643623265	1059	36.65	25	1058	40	1133	0.0e+00	847	COG1197	Transcription-repair coupling factor (superfamily II helicase)	1139
643623266	329	33.84	2	329	4	331	1.0e-69	257	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
643623267	430	49.47	48	427	2	379	1.0e-82	300	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
643623268	147	33.33	1	141	24	162	4.0e-18	83.8	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
643623269	466	37.61	4	452	16	470	1.0e-93	337	COG0246	Mannitol-1-phosphate/altronate dehydrogenases	473
643623270	345	35.41	1	343	1	350	2.0e-62	233	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
643623271	280	30.45	12	273	3	261	9.0e-40	157	COG1737	DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains	281
643623272	642	34.13	8	335	1	311	4.0e-51	196	COG0524	Sugar or nucleoside kinase, ribokinase family	311
643623272	642	51.62	340	641	7	309	1.0e-105	377	COG3892	Myo-inositol catabolism protein IolC	310
643623273	216	25.13	19	213	8	201	3.0e-14	72	COG1309	DNA-binding transcriptional regulator, AcrR family	201
643623274	242	38.19	8	240	3	251	6.0e-44	170	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
643623275	506	40.19	1	506	16	530	2.0e-108	386	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
643623276	375	29.14	1	367	1	357	8.0e-38	151	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
643623277	289	45.61	1	289	2	297	2.0e-46	179	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
643623278	331	40.95	6	314	3	314	1.0e-34	140	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
643623279	236	47.79	1	231	2	250	5.0e-65	240	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
643623280	232	51.71	1	231	3	236	6.0e-74	270	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
643623281	257	38.74	4	250	3	254	1.0e-48	186	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
643623282	237	35.54	1	236	6	244	3.0e-29	122	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
643623286	465	35.78	20	462	4	441	8.0e-67	248	COG3182	Uncharacterized iron-regulated membrane protein	442
643623287	211	36.42	9	175	18	190	5.0e-29	121	COG0110	Acetyltransferase (isoleucine patch superfamily)	190
643623288	243	31.7	12	230	2	225	8.0e-29	120	COG2186	DNA-binding transcriptional regulator, FadR family	241
643623289	326	31.5	1	322	4	329	7.0e-63	234	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
643623290	163	24.84	1	153	5	156	6.0e-10	57.3	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
643623291	432	46.13	56	430	5	379	1.0e-84	307	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
643623292	387	33.62	14	363	31	362	1.0e-63	237	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
643623294	190	29.84	1	178	2	186	2.0e-19	88.9	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
643623295	321	34.68	16	309	1	293	2.0e-38	152	COG0583	DNA-binding transcriptional regulator, LysR family	297
643623296	351	51.23	1	346	11	373	1.0e-105	376	COG2828	2-Methylaconitate cis-trans-isomerase PrpF (2-methyl citrate pathway)	378
643623297	381	26.05	29	357	4	303	3.0e-19	89.6	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
643623298	648	37.19	1	480	3	486	3.0e-87	316	COG3333	TctA family transporter	504
643623299	198	31.34	2	191	1	200	2.0e-25	109	COG0625	Glutathione S-transferase	211
643623300	453	30.02	1	414	4	415	8.0e-52	198	COG2079	2-methylcitrate dehydratase PrpD	453
643623301	451	30.72	1	421	4	425	3.0e-55	209	COG2079	2-methylcitrate dehydratase PrpD	453
643623302	439	30.21	11	419	36	452	1.0e-45	177	COG2079	2-methylcitrate dehydratase PrpD	453
643623304	255	59.75	13	253	1	240	7.0e-109	386	COG1126	ABC-type polar amino acid transport system, ATPase component	240
643623305	370	32.74	144	369	2	222	1.0e-39	157	COG0765	ABC-type amino acid transport system, permease component	222
643623306	398	50.64	11	398	9	397	2.0e-113	402	COG4597	ABC-type amino acid transport system, permease component	397
643623307	335	29.63	1	266	6	268	2.0e-25	110	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
643623308	388	38.19	1	387	1	396	7.0e-116	410	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
643623309	221	34.09	1	217	8	227	9.0e-29	120	COG1802	DNA-binding transcriptional regulator, GntR family	230
643623310	234	38.91	16	233	3	223	1.0e-33	136	COG1802	DNA-binding transcriptional regulator, GntR family	230
643623313	323	33.85	1	323	1	319	7.0e-57	214	COG3181	Tripartite-type tricarboxylate transporter, receptor component TctC	319
643623314	509	53.61	1	498	1	494	0.0e+00	506	COG3333	TctA family transporter	504
643623316	566	35.19	10	554	7	510	3.0e-86	312	COG0029	Aspartate oxidase	518
643623317	402	44.03	16	389	1	374	4.0e-94	338	COG2828	2-Methylaconitate cis-trans-isomerase PrpF (2-methyl citrate pathway)	378
643623318	468	29.15	10	445	2	440	1.0e-55	210	COG2079	2-methylcitrate dehydratase PrpD	453
643623319	185	31.76	13	179	6	173	1.0e-18	86.4	COG2059	Chromate transport protein ChrA	195
643623320	175	27.59	4	175	6	179	5.0e-15	74.1	COG2059	Chromate transport protein ChrA	195
643623321	275	50.4	21	268	1	248	7.0e-87	314	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
643623322	276	36.22	11	264	2	249	5.0e-42	164	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
643623323	273	39.92	18	265	16	258	7.0e-41	161	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
643623324	318	29.45	1	316	11	335	1.0e-29	124	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
643623325	513	22.29	18	509	6	414	1.0e-21	98.1	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
643623327	282	43.9	1	280	17	303	1.0e-57	216	COG3734	2-keto-3-deoxy-galactonokinase	306
643623328	210	32.86	1	210	3	211	3.0e-43	168	COG0800	2-keto-3-deoxy-6-phosphogluconate aldolase	211
643623329	252	39.11	28	250	16	238	3.0e-36	145	COG2186	DNA-binding transcriptional regulator, FadR family	241
643623330	599	43.38	1	584	1	574	0.0e+00	596	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
643623331	438	37.73	17	438	9	440	4.0e-81	295	COG4664	TRAP-type mannitol/chloroaromatic compound transport system, large permease component	447
643623332	198	23.03	37	188	16	157	4.0e-13	68.4	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
643623333	340	28.39	3	317	5	317	4.0e-40	158	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
643623334	348	37.68	2	345	1	350	2.0e-68	253	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
643623335	255	37.94	6	251	1	250	2.0e-41	163	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
643623336	404	29.98	1	393	4	365	3.0e-62	232	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
643623337	382	40.79	1	364	4	370	4.0e-83	301	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
643623340	439	25.68	23	419	25	411	1.0e-27	117	COG2124	Cytochrome P450	411
643623345	173	35.03	18	172	25	181	3.0e-20	91.3	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
643623346	320	37.89	6	320	2	322	6.0e-54	204	COG3712	Periplasmic ferric-dicitrate binding protein FerR, regulates iron transport through sigma-19	322
643623347	836	38.52	117	836	27	719	0.0e+00	513	COG4773	Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid	719
643623348	551	21.69	1	436	1	442	5.0e-27	116	COG3182	Uncharacterized iron-regulated membrane protein	442
643623353	306	29.43	6	301	15	301	2.0e-47	183	COG0803	ABC-type Zn uptake system ZnuABC, Zn-binding component ZnuA	303
643623354	250	35.95	12	246	1	238	2.0e-57	215	COG1121	ABC-type Mn2+/Zn2+ transport system, ATPase component	254
643623355	295	37.41	18	295	4	274	1.0e-31	130	COG1108	ABC-type Mn2+/Zn2+ transport system, permease component	274
643623358	484	50.41	3	483	1	484	0.0e+00	527	COG1492	Cobyric acid synthase	486
643623359	520	47.39	27	520	1	485	0.0e+00	540	COG1492	Cobyric acid synthase	486
643623362	139	34.78	2	115	1	113	3.0e-17	81.3	COG0789	DNA-binding transcriptional regulator, MerR family	124
643623363	262	27.14	5	261	3	280	1.0e-13	70.1	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
643623364	273	38.71	1	217	1	185	5.0e-47	181	COG2249	Putative NADPH-quinone reductase (modulator of drug activity B)	189
643623365	318	32.55	18	309	2	292	6.0e-28	118	COG0583	DNA-binding transcriptional regulator, LysR family	297
643623368	390	38.11	1	365	5	321	3.0e-79	289	COG0523	GTPase, G3E family	323
643623373	256	41.63	3	254	2	251	6.0e-41	161	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
643623374	877	42.28	13	865	29	912	0.0e+00	751	COG0474	Magnesium-transporting ATPase (P-type)	917
643623376	1119	27.96	704	910	6	203	7.0e-19	90.5	COG1014	Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, gamma subunit	203
643623376	1119	29.96	22	676	1	632	0.0e+00	485	COG4231	TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit	640
643623377	423	40.75	2	413	36	458	9.0e-69	254	COG0277	FAD/FMN-containing dehydrogenase	459
643623379	337	30.63	12	336	1	326	2.0e-46	180	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
643623380	269	35.16	1	252	3	253	6.0e-41	161	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
643623381	560	27.55	28	547	9	534	3.0e-45	176	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
643623382	248	30.25	6	241	7	241	3.0e-29	122	COG2186	DNA-binding transcriptional regulator, FadR family	241
643623383	343	22.41	1	340	4	354	1.0e-33	137	COG0687	Spermidine/putrescine-binding periplasmic protein	363
643623384	347	48.43	1	347	3	352	4.0e-112	398	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
643623385	291	40.5	12	289	6	284	2.0e-53	202	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
643623386	268	38.91	1	257	1	255	9.0e-45	173	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
643623387	596	36.27	7	563	3	537	3.0e-113	402	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
643623389	565	20.13	45	509	21	432	3.0e-19	90.5	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
643623390	131	57.45	39	131	4	97	2.0e-18	85.1	COG5477	Predicted small integral membrane protein	97
643623391	289	35.25	17	289	3	280	2.0e-49	189	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
643623392	293	31.23	8	289	11	295	5.0e-47	181	COG1175	ABC-type sugar transport system, permease component	295
643623393	362	40.29	1	350	1	338	6.0e-97	347	COG3839	ABC-type sugar transport system, ATPase component	338
643623394	360	38.55	1	344	3	335	6.0e-85	307	COG3839	ABC-type sugar transport system, ATPase component	338
643623395	511	35.04	1	500	2	499	3.0e-79	289	COG1070	Sugar (pentulose or hexulose) kinase	502
643623396	565	33.33	4	550	1	521	5.0e-88	318	COG0578	Glycerol-3-phosphate dehydrogenase	532
643623397	259	36.71	17	253	1	235	5.0e-44	171	COG2188	DNA-binding transcriptional regulator, GntR family	236
643623398	249	40.8	1	241	2	251	5.0e-39	154	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
643623399	334	43.65	29	334	8	312	3.0e-96	345	COG3958	Transketolase, C-terminal subunit	312
643623400	281	47.08	7	246	5	243	7.0e-80	290	COG3959	Transketolase, N-terminal subunit	243
643623401	292	39.54	13	269	2	251	8.0e-30	124	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
643623402	620	30.95	19	186	7	174	8.0e-18	85.8	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
643623402	620	34.4	246	620	1	375	4.0e-75	276	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
643625367	209	44.95	4	201	2	199	8.0e-41	160	COG1279	Arginine exporter protein ArgO	202
643625368	232	52.82	7	200	15	208	5.0e-58	217	COG2808	Predicted FMN-binding regulatory protein PaiB	209
643625369	169	35.77	1	137	2	131	2.0e-24	105	COG1959	DNA-binding transcriptional regulator, IscR family	150
643625371	114	25	1	104	11	114	2.0e-11	61.2	COG0599	Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family	124
643625372	195	25.79	6	195	9	196	3.0e-18	84.9	COG3932	Uncharacterized conserved protein	209
643625373	368	51.4	3	358	2	352	6.0e-107	381	COG4148	ABC-type molybdate transport system, ATPase component	352
643625374	232	55.8	5	228	1	223	3.0e-64	238	COG4149	ABC-type molybdate transport system, permease component	225
643625375	258	40.4	10	258	12	258	3.0e-46	178	COG0725	ABC-type molybdate transport system, periplasmic component	258
643625376	67	51.47	1	67	1	68	4.0e-11	59.6	COG3585	Molybdopterin-binding protein	69
643625378	277	38.01	1	267	2	269	3.0e-54	205	COG0157	Nicotinate-nucleotide pyrophosphorylase	280
643625379	262	36.76	122	189	1	68	5.0e-12	65	COG3585	Molybdopterin-binding protein	69
643625379	262	38.1	5	128	3	128	4.0e-24	105	COG2005	DNA-binding transcriptional regulator ModE (molybdenum-dependent)	130
643625380	234	37.56	6	219	13	227	2.0e-23	103	COG2186	DNA-binding transcriptional regulator, FadR family	241
643625383	281	22.81	3	278	2	286	2.0e-15	76.7	COG1344	Flagellin and related hook-associated protein FlgL	360
643625384	126	25	6	120	1	115	1.0e-08	51.9	COG5442	Flagellar biosynthesis regulator FlaF	115
643625385	135	29.92	2	128	3	127	5.0e-15	73.5	COG5443	Flagellar biosynthesis regulator FlbT	148
643625389	574	25.33	16	382	12	382	1.0e-43	171	COG3551	Uncharacterized protein	402
643625391	332	35.32	45	296	5	232	2.0e-16	80	COG2801	Transposase InsO and inactivated derivatives	232
643625394	512	25.67	181	493	7	314	9.0e-31	128	COG1397	ADP-ribosylglycohydrolase	314
643625396	133	26.55	3	115	37	148	7.0e-13	66.5	COG0782	Transcription elongation factor, GreA/GreB family	151
643625397	311	24.58	4	289	3	296	9.0e-28	117	COG0668	Small-conductance mechanosensitive channel	316
643625398	496	34.91	1	489	6	533	6.0e-102	364	COG0659	Sulfate permease or related transporter, MFS superfamily	554
643625400	156	41.89	1	148	1	147	2.0e-17	82.2	COG3238	Uncharacterized membrane protein YdcZ, DUF606 family	150
643625401	308	25.08	10	303	1	295	2.0e-20	93.1	COG0583	DNA-binding transcriptional regulator, LysR family	297
643625418	283	20.14	5	273	1	285	9.0e-16	77.6	COG0224	FoF1-type ATP synthase, gamma subunit	287
643625421	234	29.5	1	139	2	140	6.0e-08	51.4	COG0711	FoF1-type ATP synthase, membrane subunit b or b'	161
643625422	83	59.15	10	80	9	79	1.0e-07	48.3	COG0636	FoF1-type ATP synthase, membrane subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K	79
643625423	227	29.65	10	220	21	246	3.0e-30	125	COG0356	FoF1-type ATP synthase, membrane subunit a	246
643625426	146	27.13	2	128	3	128	2.0e-10	58.4	COG0355	FoF1-type ATP synthase, epsilon subunit	135
643625427	460	54.27	2	452	7	463	0.0e+00	580	COG0055	FoF1-type ATP synthase, beta subunit	468
643625430	334	31.29	3	334	2	314	2.0e-47	183	COG0451	Nucleoside-diphosphate-sugar epimerase	314
643625437	452	24.32	5	444	6	396	1.0e-44	174	COG3551	Uncharacterized protein	402
643625441	266	25	17	256	18	254	1.0e-26	113	COG1682	ABC-type polysaccharide/polyol phosphate export permease	263
643625442	589	32.38	244	589	32	371	3.0e-64	240	COG3524	Capsule polysaccharide export protein KpsE/RkpR	372
643625443	273	32.58	1	217	24	243	6.0e-58	217	COG1134	ABC-type polysaccharide/polyol phosphate transport system, ATPase component	249
643625445	511	27.42	184	479	2	245	6.0e-28	119	COG1192	Cellulose biosynthesis protein BcsQ	259
643625447	368	26.62	48	295	19	296	5.0e-15	75.9	COG5534	Plasmid replication initiator protein	383
643625448	312	19.63	7	268	3	268	1.0e-09	57.1	COG0463	Glycosyltransferase involved in cell wall bisynthesis	291
643625449	187	51.69	1	178	1	173	4.0e-54	204	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase or related enzyme	173
643625450	346	58.74	1	346	1	340	0.0e+00	513	COG1088	dTDP-D-glucose 4,6-dehydratase	340
643625451	283	48.76	1	278	2	280	4.0e-80	291	COG1091	dTDP-4-dehydrorhamnose reductase	281
643625452	296	53.63	4	292	1	286	6.0e-104	370	COG1209	dTDP-glucose pyrophosphorylase	286
643625454	669	62.96	398	667	4	273	9.0e-119	421	COG2877	3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase	279
643625456	432	20.9	71	412	58	346	4.0e-07	50	COG1566	Multidrug resistance efflux pump	352
643625457	724	40.03	21	720	14	709	0.0e+00	548	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
643625458	598	34.79	35	591	43	611	6.0e-97	348	COG3914	Predicted O-linked N-acetylglucosamine transferase, SPINDLY family	620
643625462	212	47.76	8	207	8	208	2.0e-47	182	COG2860	Uncharacterized membrane protein YeiH	209
643625463	169	42.67	16	164	6	154	7.0e-34	136	COG1522	DNA-binding transcriptional regulator, Lrp family	154
643625465	291	65.61	7	291	3	287	3.0e-95	341	COG4208	ABC-type sulfate transport system, permease component	287
643625466	277	56.93	2	275	1	274	7.0e-68	250	COG0555	ABC-type sulfate transport system, permease component	274
643625467	334	65.06	11	331	14	344	2.0e-127	448	COG1613	ABC-type sulfate transport system, periplasmic component	348
643625468	299	31.23	2	295	1	295	5.0e-15	75.4	COG0583	DNA-binding transcriptional regulator, LysR family	297
643626406	266	24.37	4	262	6	280	5.0e-23	101	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
643626407	247	41.57	3	245	1	251	1.0e-36	146	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
643626408	300	32.78	5	300	4	296	8.0e-30	124	COG0583	DNA-binding transcriptional regulator, LysR family	297
643626409	397	19.85	13	383	14	383	1.0e-13	71	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
643626410	230	43.59	1	227	21	251	2.0e-36	146	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
643626411	175	29.81	5	163	4	162	9.0e-29	119	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
643626412	337	28.11	1	337	5	337	7.0e-61	227	COG2222	Fructoselysine-6-P-deglycase FrlB and related proteins with duplicated sugar isomerase (SIS) domain	340
643626413	499	41.9	43	471	41	459	4.0e-98	352	COG0165	Argininosuccinate lyase	459
643626414	457	27.03	18	424	22	428	2.0e-33	136	COG2079	2-methylcitrate dehydratase PrpD	453
643626415	243	34.25	3	220	10	222	9.0e-35	140	COG0765	ABC-type amino acid transport system, permease component	222
643626416	222	40	1	219	3	222	3.0e-43	168	COG0765	ABC-type amino acid transport system, permease component	222
643626417	280	28.1	10	272	3	275	1.0e-28	120	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
643626418	250	61.09	11	249	3	240	6.0e-114	403	COG1126	ABC-type polar amino acid transport system, ATPase component	240
643626419	332	35.54	6	330	17	345	4.0e-56	212	COG0252	L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D	351
643626420	241	32.78	1	240	1	236	2.0e-38	152	COG2188	DNA-binding transcriptional regulator, GntR family	236
643626421	375	52.96	1	355	1	338	3.0e-122	431	COG3839	ABC-type sugar transport system, ATPase component	338
643626422	470	28.39	35	417	1	376	1.0e-38	154	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
643626423	285	27.12	7	262	2	295	5.0e-25	108	COG0524	Sugar or nucleoside kinase, ribokinase family	311
643626424	285	31.62	16	256	11	254	6.0e-24	104	COG1082	Sugar phosphate isomerase/epimerase	274
643626425	281	40	13	281	7	281	6.0e-56	211	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
643626426	322	38.1	26	319	1	291	9.0e-58	217	COG1175	ABC-type sugar transport system, permease component	295
643626427	429	24.37	1	428	4	429	7.0e-34	138	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
643626428	312	25.08	25	303	17	318	3.0e-24	106	COG2222	Fructoselysine-6-P-deglycase FrlB and related proteins with duplicated sugar isomerase (SIS) domain	340
643626429	350	43.24	14	345	1	332	3.0e-75	275	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
643626430	491	38.18	13	460	2	456	2.0e-72	267	COG0277	FAD/FMN-containing dehydrogenase	459
643626431	267	30.58	7	245	4	241	6.0e-31	127	COG2186	DNA-binding transcriptional regulator, FadR family	241
643626432	130	32.69	25	126	13	109	1.0e-11	62.2	COG0607	Rhodanese-related sulfurtransferase	110
643626433	189	25.49	33	182	25	177	6.0e-17	80.6	COG2128	Alkylhydroperoxidase family enzyme, contains CxxC motif	177
643626434	767	29.97	3	744	43	762	2.0e-119	424	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
643626435	516	27.56	1	516	2	530	1.0e-81	297	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
643626436	506	28.68	3	491	2	502	3.0e-56	212	COG1070	Sugar (pentulose or hexulose) kinase	502
643626437	225	41.1	1	213	1	219	5.0e-48	184	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
643626438	349	36.62	36	348	6	315	8.0e-75	274	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
643626439	397	44.39	5	381	6	386	9.0e-106	377	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
643626440	253	22.36	1	216	1	224	3.0e-14	72.2	COG2057	Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit	225
643626441	268	29.13	26	227	30	220	2.0e-18	86	COG1788	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit	220
643626442	361	46.46	10	361	4	351	2.0e-108	385	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
643626443	594	39.51	4	289	4	287	6.0e-50	192	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
643626443	594	40.15	329	592	1	264	8.0e-51	195	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
643626444	360	27.93	1	321	4	330	3.0e-37	149	COG0687	Spermidine/putrescine-binding periplasmic protein	363
643626445	251	39.68	3	247	1	246	4.0e-57	214	COG1414	DNA-binding transcriptional regulator, IclR family	246
643626447	275	37.6	8	257	1	250	7.0e-59	220	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
643626448	429	23.36	1	429	4	431	1.0e-37	151	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
643626449	278	40.5	5	278	14	292	4.0e-52	198	COG1175	ABC-type sugar transport system, permease component	295
643626450	270	34.31	4	269	8	281	4.0e-43	168	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
643626451	352	54.89	1	348	1	338	2.0e-124	439	COG3839	ABC-type sugar transport system, ATPase component	338
643626452	337	35.61	1	335	2	350	8.0e-62	231	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
643626453	481	49.15	8	473	2	464	0.0e+00	486	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
643626454	351	50.43	7	350	6	345	7.0e-125	440	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
643626455	289	32.18	7	286	11	299	1.0e-51	197	COG3684	Tagatose-1,6-bisphosphate aldolase	306
643626456	295	31.17	2	295	3	310	3.0e-30	125	COG0524	Sugar or nucleoside kinase, ribokinase family	311
643626457	322	24.69	24	320	46	367	8.0e-14	71.4	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
643626459	354	34.01	8	346	6	349	3.0e-37	149	COG3180	Uncharacterized membrane protein AbrB, regulator of aidB expression	352
643626460	399	28.57	158	399	30	248	2.0e-16	80.7	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
643626461	250	37.21	1	248	6	263	5.0e-51	194	COG0300	Short-chain dehydrogenase	265
643626462	387	25.73	17	378	31	396	2.0e-11	63.7	COG2223	Nitrate/nitrite transporter NarK	417
643626465	392	32.23	112	382	3	259	2.0e-48	186	COG1192	Cellulose biosynthesis protein BcsQ	259
643626466	316	30.37	45	232	2	185	2.0e-18	86.9	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
643626468	242	29.41	1	236	3	236	2.0e-32	132	COG2188	DNA-binding transcriptional regulator, GntR family	236
643626469	689	44.33	18	684	18	636	2.0e-125	443	COG4666	TRAP-type uncharacterized transport system, fused permease components	642
643626470	329	34.48	8	320	3	321	4.0e-58	218	COG2358	TRAP-type uncharacterized transport system, periplasmic component	321
643626471	451	41.34	20	449	5	437	6.0e-109	388	COG0015	Adenylosuccinate lyase	438
643626472	481	47.4	1	462	1	462	0.0e+00	505	COG0114	Fumarate hydratase class II	462
643626473	391	28.49	24	387	23	371	1.0e-37	151	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
643626474	548	28.93	20	548	21	554	1.0e-65	244	COG0747	ABC-type transport system, periplasmic component	556
643626475	468	37.77	15	419	1	413	2.0e-79	289	COG0015	Adenylosuccinate lyase	438
643626476	328	47.19	1	319	1	314	1.0e-76	280	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
643626477	391	40.48	140	391	37	288	5.0e-59	222	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
643626478	317	52.24	1	309	4	312	8.0e-112	396	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
643626479	326	44.23	1	311	4	263	2.0e-91	329	COG4608	ABC-type oligopeptide transport system, ATPase component	309
643626480	294	27.61	1	293	1	291	1.0e-24	107	COG0583	DNA-binding transcriptional regulator, LysR family	297
643626481	980	27.31	755	969	8	216	3.0e-29	124	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
643626482	447	35.4	1	290	7	295	7.0e-60	225	COG1230	Co/Zn/Cd efflux system component	296
643626483	319	39.89	137	317	1	180	1.0e-33	137	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
643626484	489	35.7	18	489	4	457	2.0e-87	316	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
643626485	333	31.15	1	317	1	318	2.0e-64	239	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
643626486	633	34.21	1	152	5	155	4.0e-18	86.9	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
643626486	633	42.78	238	632	3	379	1.0e-82	301	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
643626488	462	24.87	51	430	1	375	3.0e-40	160	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
643626489	591	32.62	1	560	2	533	4.0e-116	412	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
643626490	339	36.73	16	339	14	334	2.0e-57	216	COG2855	Uncharacterized membrane protein YadS	334
643626491	332	50.9	4	320	2	326	2.0e-78	286	COG0280	Phosphotransacetylase	327
643626499	1100	25.57	588	1097	1	510	1.0e-08	56.1	COG2931	Ca2+-binding protein, RTX toxin-related	510
643626502	339	41.98	6	332	10	340	9.0e-68	250	COG5397	Uncharacterized protein	349
643626503	396	31.86	84	392	1	304	2.0e-34	140	COG3509	Poly(3-hydroxybutyrate) depolymerase	312
643626505	306	36.93	2	283	28	313	6.0e-42	164	COG0451	Nucleoside-diphosphate-sugar epimerase	314
643626509	481	26.37	7	360	7	363	5.0e-43	169	COG3551	Uncharacterized protein	402
643626510	566	39.06	7	256	6	260	1.0e-41	164	COG0467	RecA-superfamily ATPase, KaiC/GvpD/RAD55 family	260
643626512	478	33.33	268	477	3	216	4.0e-36	146	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
643626514	149	41.72	1	149	4	151	4.0e-18	84.3	COG0589	Nucleotide-binding universal stress protein,  UspA family	154
643626515	353	27.16	277	352	14	94	1.0e-07	50.8	COG0633	Ferredoxin	102
643626515	353	33.33	12	293	1	266	3.0e-63	235	COG1018	Ferredoxin-NADP reductase	266
643626516	410	32.15	19	408	4	367	4.0e-71	262	COG4638	Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit	367
643626517	297	29.28	1	297	3	295	6.0e-28	118	COG0583	DNA-binding transcriptional regulator, LysR family	297
643626518	269	36.36	1	256	2	263	4.0e-36	145	COG0345	Pyrroline-5-carboxylate reductase	266
643626519	162	33.33	1	156	9	166	2.0e-23	102	COG3685	Ferritin-like metal-binding protein YciE	167
643626521	78	42.31	1	78	3	79	9.0e-15	71.8	COG2155	Uncharacterized membrane protein YuzA, DUF378 family	79
643626524	739	41.3	9	479	13	482	5.0e-107	382	COG3901	Regulator of nitric oxide reductase transcription	482
643626525	644	57.65	1	641	1	637	0.0e+00	796	COG4263	Nitrous oxide reductase	637
643626526	438	50.75	11	406	3	401	2.0e-120	425	COG3420	Nitrous oxidase accessory protein NosD, contains tandem CASH domains	408
643626527	294	36.67	1	292	4	293	3.0e-65	242	COG1131	ABC-type multidrug transport system, ATPase component	293
643626528	273	23.55	1	270	1	274	3.0e-14	72.8	COG1277	ABC-type transport system involved in multi-copper enzyme maturation, permease component	278
643626529	180	46.86	1	168	1	172	2.0e-33	135	COG4314	Nitrous oxide reductase accessory protein NosL	176
643626530	300	32.27	1	294	3	312	3.0e-42	165	COG1477	Thiamine biosynthesis lipoprotein ApbE	337
643626531	93	21.69	16	93	1	83	1.0e-08	51.2	COG5591	Uncharacterized protein	103
643626532	229	42.48	11	226	1	225	1.0e-52	199	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
643626533	438	28.98	131	437	21	328	1.0e-29	124	COG0642	Signal transduction histidine kinase	336
643626535	776	27.15	2	770	83	860	0.0e+00	682	COG2609	Pyruvate dehydrogenase complex, dehydrogenase (E1) component	887
643626536	154	48.97	5	149	6	149	3.0e-33	134	COG1522	DNA-binding transcriptional regulator, Lrp family	154
643626537	263	36.4	1	252	1	250	2.0e-42	165	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
643626538	248	34.98	1	223	5	223	2.0e-34	139	COG1802	DNA-binding transcriptional regulator, GntR family	230
643626540	317	40.93	6	242	3	234	6.0e-56	211	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
643626541	310	48.04	3	305	1	298	4.0e-88	318	COG3246	Uncharacterized conserved protein, DUF849 family	298
643626542	417	25.94	26	368	6	342	3.0e-35	143	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
643626543	293	37.41	1	291	2	294	5.0e-38	151	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
643626544	337	32.8	25	329	10	314	3.0e-36	146	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
643626545	260	42	4	253	2	250	5.0e-70	257	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
643626546	235	45.11	1	234	3	237	3.0e-72	265	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
643626547	251	41.73	3	248	2	250	4.0e-41	161	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
643626548	177	49.43	1	175	1	176	2.0e-43	168	COG0250	Transcription antitermination factor NusG	178
643626549	150	57.72	2	150	1	140	3.0e-44	171	COG0080	Ribosomal protein L11	141
643626550	232	63.88	1	226	1	227	3.0e-78	285	COG0081	Ribosomal protein L1	228
643626551	163	37.58	1	163	11	175	1.0e-31	129	COG0244	Ribosomal protein L10	175
643626552	125	56.35	1	125	2	124	3.0e-20	90.7	COG0222	Ribosomal protein L7/L12	124
643626554	1415	50.76	21	850	6	808	0.0e+00	880	COG0086	DNA-directed RNA polymerase, beta' subunit/160 kD subunit	808
643626557	156	59.46	2	149	1	148	8.0e-54	202	COG0049	Ribosomal protein S7	148
643626558	705	60.48	1	704	1	691	0.0e+00	950	COG0480	Translation elongation factor EF-G, a GTPase	697
643626559	391	77.02	1	391	1	394	0.0e+00	688	COG0050	Translation elongation factor EF-Tu, a GTPase	394
643626560	102	69.61	1	102	1	102	4.0e-38	149	COG0051	Ribosomal protein S10	104
643626561	240	53.67	2	216	1	218	8.0e-74	270	COG0087	Ribosomal protein L3	218
643626562	206	40.95	1	206	2	211	5.0e-47	180	COG0088	Ribosomal protein L4	214
643626563	98	56.38	7	98	1	94	3.0e-20	90.3	COG0089	Ribosomal protein L23	94
643626564	279	61.68	1	273	1	274	4.0e-105	374	COG0090	Ribosomal protein L2	275
643626565	92	64.52	1	92	1	93	1.0e-34	137	COG0185	Ribosomal protein S19	93
643626566	126	52.63	11	124	7	120	5.0e-29	119	COG0091	Ribosomal protein L22	120
643626567	238	59.65	12	238	1	228	2.0e-78	285	COG0092	Ribosomal protein S3	233
643626568	137	63.77	1	136	2	139	1.0e-47	181	COG0197	Ribosomal protein L16/L10AE	146
643626569	68	55.88	1	68	2	69	3.0e-11	59.9	COG0255	Ribosomal protein L29	69
643626570	80	58.11	1	74	6	79	6.0e-21	92.6	COG0186	Ribosomal protein S17	87
643626571	122	77.87	1	122	1	122	9.0e-49	185	COG0093	Ribosomal protein L14	122
643626572	101	52.38	1	101	1	103	6.0e-19	85.7	COG0198	Ribosomal protein L24	104
643626573	186	60.45	8	184	1	177	2.0e-71	262	COG0094	Ribosomal protein L5	180
643626574	101	52.46	41	101	1	61	3.0e-17	79.9	COG0199	Ribosomal protein S14	61
643626575	130	54.2	1	130	3	132	3.0e-44	170	COG0096	Ribosomal protein S8	132
643626576	163	56.52	2	162	16	176	2.0e-50	191	COG0097	Ribosomal protein L6P/L9E	178
643626577	119	53.33	4	119	7	125	2.0e-27	114	COG0256	Ribosomal protein L18	125
643626578	187	56.25	4	179	6	181	4.0e-55	207	COG0098	Ribosomal protein S5	181
643626579	62	43.4	7	59	3	55	7.0e-10	55.5	COG1841	Ribosomal protein L30/L7E	55
643626580	161	48.41	1	152	1	152	1.0e-29	122	COG0200	Ribosomal protein L15	152
643626581	445	48.27	7	430	10	435	9.0e-117	413	COG0201	Preprotein translocase subunit SecY	436
643626582	218	39.91	4	215	2	178	1.0e-42	166	COG0563	Adenylate kinase or related kinase	178
643626583	122	65.29	1	121	1	121	6.0e-43	165	COG0099	Ribosomal protein S13	121
643626584	129	70.54	1	129	1	129	4.0e-47	180	COG0100	Ribosomal protein S11	129
643626585	338	49.17	25	325	15	314	2.0e-91	329	COG0202	DNA-directed RNA polymerase, alpha subunit/40 kD subunit	317
643626586	139	63.79	1	116	1	116	2.0e-42	164	COG0203	Ribosomal protein L17	116
643626588	461	43.3	5	355	4	338	2.0e-66	247	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
643626589	437	53.01	11	436	5	436	0.0e+00	578	COG2256	Replication-associated recombination protein RarA (DNA-dependent ATPase)	436
643626590	117	47.46	2	116	9	126	1.0e-16	78.3	COG0239	Fluoride ion exporter CrcB/FEX, affects chromosome condensation	126
643626591	343	33.96	1	318	1	288	2.0e-64	239	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
643626592	235	43.86	7	232	33	260	3.0e-53	201	COG5387	Chaperone required for the assembly of the mitochondrial F1-ATPase	264
643626593	338	33.33	1	270	3	273	2.0e-30	127	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
643626594	420	45.11	4	420	5	397	3.0e-103	368	COG4597	ABC-type amino acid transport system, permease component	397
643626595	442	33.49	232	438	19	219	5.0e-40	159	COG0765	ABC-type amino acid transport system, permease component	222
643626596	262	63.18	22	260	3	240	2.0e-116	411	COG1126	ABC-type polar amino acid transport system, ATPase component	240
643626597	122	22.02	1	109	1	90	4.0e-08	50.4	COG0633	Ferredoxin	102
643626598	405	32.91	19	397	1	378	8.0e-52	197	COG0006	Xaa-Pro aminopeptidase	384
643626601	113	48.21	4	113	5	116	4.0e-28	116	COG3450	Predicted enzyme of the cupin superfamily	116
643626602	267	58.37	7	261	10	266	2.0e-98	352	COG0413	Ketopantoate hydroxymethyltransferase	268
643626603	279	55.71	4	279	3	282	6.0e-96	343	COG0414	Panthothenate synthetase	285
643626604	423	32.87	4	421	2	408	8.0e-60	224	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
643626607	805	39.55	150	804	1	650	0.0e+00	579	COG0072	Phenylalanyl-tRNA synthetase beta subunit	650
643626610	360	51.01	1	343	3	335	9.0e-118	416	COG0016	Phenylalanyl-tRNA synthetase alpha subunit	335
643626611	120	63.33	1	120	1	118	1.0e-36	145	COG0292	Ribosomal protein L20	118
643626612	68	53.12	3	66	1	64	4.0e-11	59.8	COG0291	Ribosomal protein L35	65
643626613	472	44.95	2	459	11	475	0.0e+00	509	COG0469	Pyruvate kinase	477
643626614	250	45.06	2	249	6	254	6.0e-63	234	COG3931	Predicted N-formylglutamate amidohydrolase	263
643626615	288	35.21	5	282	2	279	2.0e-57	216	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
643626616	320	35.03	2	320	6	355	3.0e-49	189	COG4948	L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily	372
643626617	333	39.24	24	332	32	337	1.0e-64	240	COG3367	Uncharacterized conserved protein, NAD-dependent epimerase/dehydratase family	339
643626618	341	37.21	41	341	3	280	1.0e-62	233	COG2301	Citrate lyase beta subunit	283
643626619	156	31.37	6	155	3	153	4.0e-19	87.6	COG3449	DNA gyrase inhibitor GyrI	154
643626620	322	57.14	3	317	1	314	2.0e-120	425	COG0825	Acetyl-CoA carboxylase alpha subunit	317
643626621	104	54.81	1	104	1	104	3.0e-21	93.2	COG2076	Multidrug transporter EmrE and related cation transporters	106
643626623	392	39.7	1	392	7	399	3.0e-73	269	COG2133	Glucose/arabinose dehydrogenase, beta-propeller fold	399
643626625	156	52	6	155	1	150	7.0e-39	153	COG0782	Transcription elongation factor, GreA/GreB family	151
643626627	551	29.41	465	548	21	96	2.0e-06	47.7	COG2440	Ferredoxin-like protein FixX	99
643626627	551	31.58	10	464	2	396	2.0e-73	270	COG0644	Dehydrogenase (flavoprotein)	396
643626628	566	24.88	302	502	45	239	6.0e-09	56.2	COG5010	Flp pilus assembly protein TadD, contains TPR repeats	257
643626629	278	42.31	1	278	3	285	2.0e-71	262	COG1947	4-diphosphocytidyl-2C-methyl-D-erythritol kinase	289
643626631	473	31.16	21	425	30	399	1.0e-72	267	COG2133	Glucose/arabinose dehydrogenase, beta-propeller fold	399
643626632	132	32.33	1	129	20	152	1.0e-15	75.3	COG4244	Uncharacterized membrane protein	160
643626635	334	40.36	3	325	1	332	2.0e-74	273	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
643626636	835	37.5	170	241	11	82	1.0e-13	72.1	COG1925	Phosphotransferase system, HPr and related phosphotransfer proteins	88
643626636	835	44.68	6	146	2	142	3.0e-36	147	COG4668	Mannitol/fructose-specific phosphotransferase system, IIA domain	142
643626636	835	47.36	276	833	3	568	0.0e+00	588	COG1080	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria)	574
643626637	328	44.3	3	307	1	305	7.0e-77	280	COG1105	Fructose-1-phosphate kinase or kinase (PfkB)	310
643626638	581	60.36	238	572	1	336	6.0e-89	322	COG1299	Phosphotransferase system, fructose-specific IIC component	343
643626639	108	63.89	1	108	1	108	3.0e-22	96.4	COG1742	Uncharacterized inner membrane protein YnfA, drug/metabolite transporter superfamily	109
643626640	141	34.78	2	115	1	115	4.0e-20	90.6	COG0789	DNA-binding transcriptional regulator, MerR family	124
643626641	732	42.8	3	726	5	710	0.0e+00	617	COG2217	Cation transport ATPase	713
643626642	173	43.27	3	173	1	167	6.0e-34	136	COG0629	Single-stranded DNA-binding protein	167
643626644	430	55.27	1	423	1	425	0.0e+00	537	COG0172	Seryl-tRNA synthetase	429
643626645	185	41.44	12	185	5	179	7.0e-32	130	COG2032	Cu/Zn superoxide dismutase	179
643626647	108	39.8	11	108	1	97	2.0e-21	94.1	COG1862	Preprotein translocase subunit YajC	97
643626648	554	44.82	59	552	24	504	2.0e-120	426	COG0342	Preprotein translocase subunit SecD	506
643626649	324	42.22	5	318	1	305	5.0e-75	274	COG0341	Preprotein translocase subunit SecF	305
643626650	117	41.46	1	116	5	127	2.0e-21	94.6	COG3737	Uncharacterized conserved protein, contains Mth938-like domain	127
643626651	210	41.79	1	187	1	201	2.0e-43	168	COG4133	ABC-type transport system involved in cytochrome c biogenesis, ATPase component	209
643626652	218	54.38	1	217	4	220	2.0e-39	156	COG2386	ABC-type transport system involved in cytochrome c biogenesis, permease component	221
643626653	244	37.39	1	229	34	262	1.0e-26	113	COG0755	ABC-type transport system involved in cytochrome c biogenesis, permease component	281
643626655	174	31.25	25	148	1	126	4.0e-10	58	COG0526	Thiol-disulfide isomerase or thioredoxin	127
643626656	894	63.1	8	893	1	861	0.0e+00	1215	COG1048	Aconitase A	861
643626657	207	41.86	2	206	44	255	1.0e-45	176	COG5429	Uncharacterized protein	261
643626659	347	47.8	11	323	4	314	2.0e-101	362	COG0180	Tryptophanyl-tRNA synthetase	314
643626661	513	39.96	1	507	4	516	2.0e-87	317	COG0728	Peptidoglycan biosynthesis protein MviN/MurJ, putative lipid II flippase	518
643626662	930	39.68	42	923	2	864	0.0e+00	732	COG2844	UTP:GlnB (protein PII) uridylyltransferase	867
643626663	391	20.35	41	360	7	340	8.0e-11	61.6	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
643626664	295	45.49	16	291	1	274	4.0e-77	281	COG0313	16S rRNA C1402 (ribose-2'-O) methylase RsmI	275
643626665	117	35.71	6	115	1	112	4.0e-16	76.8	COG0792	Predicted endonuclease distantly related to archaeal Holliday junction resolvase	114
643626666	316	35.38	5	315	1	316	3.0e-63	235	COG0189	Glutathione synthase/RimK-type ligase, ATP-grasp superfamily	318
643626668	514	51.24	18	498	5	485	0.0e+00	537	COG0606	Predicted ATPase with chaperone activity	490
643626670	770	47.92	1	624	1	605	0.0e+00	645	COG0370	Fe2+ transport system protein B	653
643626671	79	44.59	3	76	1	73	5.0e-14	69.5	COG1918	Fe2+ transport system protein FeoA	75
643626672	82	29.33	7	80	1	75	2.0e-06	44.4	COG1918	Fe2+ transport system protein FeoA	75
643626673	169	55.15	5	169	1	165	5.0e-44	170	COG3685	Ferritin-like metal-binding protein YciE	167
643626674	766	20.47	56	758	44	762	9.0e-86	312	COG0243	Anaerobic selenocysteine-containing dehydrogenase	765
643626675	514	31.54	49	315	2	254	2.0e-34	140	COG0171	NH3-dependent NAD+ synthetase	268
643626675	514	39.38	353	511	5	162	5.0e-29	122	COG1546	Nicotinamide mononucleotide (NMN) deamidase PncC	162
643626676	181	48.72	2	155	9	161	8.0e-41	160	COG0521	Molybdopterin biosynthesis enzyme MoaB	169
643626677	374	43.97	1	371	1	364	2.0e-113	402	COG1062	Zn-dependent alcohol dehydrogenase	366
643626678	473	41.59	14	470	1	453	4.0e-113	402	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
643626679	351	28.09	88	351	16	244	6.0e-52	198	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
643626680	310	45.72	2	304	5	301	4.0e-77	281	COG0109	Polyprenyltransferase (heme O synthase)	304
643626682	191	50	7	181	11	186	6.0e-57	213	COG3175	Cytochrome c oxidase assembly protein Cox11	195
643626683	266	41.63	58	265	10	207	6.0e-42	164	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
643626684	223	35.19	3	220	11	243	6.0e-35	140	COG3346	Cytochrome oxidase assembly protein ShyY1	252
643626685	466	33.12	6	462	1	410	4.0e-94	338	COG0498	Threonine synthase	411
643626686	419	39	7	411	21	438	1.0e-87	317	COG0612	Predicted Zn-dependent peptidase	438
643626687	194	30.6	9	190	4	185	2.0e-23	102	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
643626688	268	19.46	48	257	4	258	1.0e-11	63.6	COG2220	L-ascorbate metabolism protein UlaG, beta-lactamase superfamily	258
643626689	471	36.26	20	471	10	459	8.0e-71	261	COG0277	FAD/FMN-containing dehydrogenase	459
643626690	178	50	4	177	6	179	8.0e-45	173	COG0503	Adenine/guanine phosphoribosyltransferase or related PRPP-binding protein	179
643626691	290	38.52	2	240	16	256	4.0e-61	228	COG0005	Purine nucleoside phosphorylase	262
643626692	194	29.05	9	187	4	176	6.0e-29	120	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
643626693	161	37.58	6	158	8	163	5.0e-25	107	COG3153	Predicted N-acetyltransferase YhbS	171
643626695	200	37.89	10	198	2	178	1.0e-31	129	COG2917	Intracellular septation protein A	180
643626697	381	54.84	106	378	62	340	4.0e-101	361	COG0552	Signal recognition particle GTPase	340
643626699	519	42.04	13	500	2	431	1.0e-121	430	COG1570	Exonuclease VII, large subunit	440
643626702	426	52.83	7	426	1	423	0.0e+00	520	COG0151	Phosphoribosylamine-glycine ligase	428
643626703	508	29.8	151	492	7	341	8.0e-54	205	COG0469	Pyruvate kinase	477
643626704	415	41.7	2	412	6	447	6.0e-109	388	COG0527	Aspartokinase	447
643626705	747	46.96	13	726	5	726	0.0e+00	680	COG3605	Signal transduction protein containing GAF and PtsI domains	756
643626706	408	45.71	16	408	2	395	4.0e-123	435	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
643626707	359	28.67	68	333	4	277	4.0e-46	178	COG1469	GTP cyclohydrolase FolE2	289
643626708	482	31.65	3	482	2	488	4.0e-64	239	COG0168	Trk-type K+ transport system, membrane component	499
643626709	484	35.54	3	484	2	488	3.0e-68	253	COG0168	Trk-type K+ transport system, membrane component	499
643626711	312	65.67	7	305	3	291	0.0e+00	503	COG0752	Glycyl-tRNA synthetase, alpha subunit	298
643626714	728	41.66	1	728	3	691	0.0e+00	709	COG0751	Glycyl-tRNA synthetase, beta subunit	691
643626715	848	25.33	25	840	20	740	8.0e-110	392	COG0574	Phosphoenolpyruvate synthase/pyruvate phosphate dikinase	740
643626718	300	29.41	25	140	2	120	9.0e-13	67.9	COG1539	Dihydroneopterin aldolase	121
643626719	345	53.21	69	332	6	265	9.0e-69	254	COG0294	Dihydropteroate synthase	274
643626720	447	49.13	1	447	5	461	1.0e-122	433	COG1109	Phosphomannomutase	464
643626722	340	63.02	1	338	3	338	0.0e+00	522	COG0059	Ketol-acid reductoisomerase	338
643626723	151	33.11	1	151	5	154	2.0e-18	84.7	COG1522	DNA-binding transcriptional regulator, Lrp family	154
643626724	152	44.52	1	146	3	147	3.0e-24	104	COG1522	DNA-binding transcriptional regulator, Lrp family	154
643626725	375	29.66	25	374	29	364	1.0e-54	206	COG0075	Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism protein PucG	383
643626726	399	34.42	4	397	1	384	5.0e-52	198	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
643626728	215	24.66	6	213	1	222	3.0e-18	85.3	COG1011	FMN phosphatase YigB, HAD superfamily	229
643626729	211	40.5	5	202	21	220	3.0e-28	118	COG1802	DNA-binding transcriptional regulator, GntR family	230
643626730	636	25.73	208	615	4	403	3.0e-43	170	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
643626731	262	37.56	11	219	9	228	3.0e-31	128	COG1376	Lipoprotein-anchoring transpeptidase ErfK/SrfK	232
643626732	387	55.41	9	387	1	368	0.0e+00	538	COG0505	Carbamoylphosphate synthase small subunit	368
643626733	152	49.67	1	151	1	147	6.0e-35	139	COG1610	Uncharacterized conserved protein YqeY	148
643626734	176	28.1	24	176	12	163	1.0e-16	79.2	COG5488	Uncharacterized membrane protein	164
643626735	566	53.21	17	557	7	517	0.0e+00	546	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
643626736	215	46.7	3	214	12	211	5.0e-74	270	COG0321	Lipoate-protein ligase B	221
643626739	367	46.13	6	366	1	352	2.0e-113	402	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
643626740	363	27.6	9	359	15	362	8.0e-42	164	COG0687	Spermidine/putrescine-binding periplasmic protein	363
643626741	428	49.12	201	428	61	286	1.0e-59	224	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
643626742	302	36.65	19	299	14	267	1.0e-52	200	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
643626743	55	42.55	7	53	4	50	3.0e-07	46.7	COG0267	Ribosomal protein L33	50
643626745	246	44.54	20	244	17	228	1.0e-32	133	COG0670	Integral membrane protein, interacts with FtsH	233
643626747	311	31.88	5	286	1	296	4.0e-25	108	COG0583	DNA-binding transcriptional regulator, LysR family	297
643626748	335	40.85	17	335	1	326	2.0e-62	232	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
643626750	266	32.17	11	265	3	260	9.0e-47	180	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
643626752	787	28.48	484	787	1	311	2.0e-30	128	COG0668	Small-conductance mechanosensitive channel	316
643626753	433	32.56	6	432	1	409	9.0e-74	271	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
643626754	459	41.69	21	458	9	447	4.0e-105	375	COG2239	Mg/Co/Ni transporter MgtE (contains CBS domain)	451
643626755	183	31.44	3	183	1	191	1.0e-27	116	COG0212	5-formyltetrahydrofolate cyclo-ligase	191
643626758	282	20.64	7	223	6	219	7.0e-07	48.1	COG5010	Flp pilus assembly protein TadD, contains TPR repeats	257
643626760	326	29.96	90	324	84	319	8.0e-18	84.9	COG2064	Pilus assembly protein TadC	320
643626761	322	25.55	8	322	4	309	5.0e-37	148	COG4965	Flp pilus assembly protein TadB	309
643626762	485	55.83	88	447	1	355	2.0e-117	416	COG4962	Pilus assembly protein, ATPase of CpaF family	355
643626763	423	27.41	93	423	24	353	2.0e-29	123	COG4963	Flp pilus assembly protein, ATPase CpaE	366
643626764	213	35.97	34	170	52	189	1.0e-24	106	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
643626765	461	38.11	12	438	3	430	2.0e-91	329	COG4964	Flp pilus assembly protein, secretin CpaC	455
643626766	274	32.1	1	236	1	241	8.0e-29	121	COG3745	Flp pilus assembly protein CpaB	276
643626769	290	29.96	42	262	35	279	4.0e-16	79	COG0741	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)	296
643626770	96	41.11	6	93	7	96	6.0e-20	88.8	COG2388	Predicted acetyltransferase, GNAT superfamily	99
643626771	209	62.5	3	209	6	213	1.0e-77	282	COG2057	Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit	225
643626772	232	55.76	1	217	1	216	8.0e-79	286	COG1788	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit	220
643626774	297	26.35	1	292	1	296	4.0e-27	115	COG0583	DNA-binding transcriptional regulator, LysR family	297
643626776	199	37.95	4	197	10	203	1.0e-31	129	COG3917	2-hydroxychromene-2-carboxylate isomerase	203
643626778	310	34.29	19	293	10	281	6.0e-39	155	COG4757	Predicted alpha/beta hydrolase	281
643626779	181	47.09	4	174	10	180	2.0e-40	158	COG3911	Predicted ATPase	183
643626780	515	40.89	233	501	3	269	4.0e-61	229	COG2240	Pyridoxal/pyridoxine/pyridoxamine kinase	281
643626780	515	55.11	1	176	1	173	1.0e-53	204	COG2258	Uncharacterized conserved protein YiiM, contains MOSC domain	210
643626782	472	39.56	16	468	2	451	4.0e-90	325	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
643626783	328	54.49	5	314	9	317	1.0e-105	376	COG0502	Biotin synthase or related enzyme	335
643626784	185	43.71	24	185	18	181	1.0e-19	89.5	COG1268	Biotin transporter BioY	184
643626785	222	33.97	1	205	9	217	8.0e-31	127	COG1802	DNA-binding transcriptional regulator, GntR family	230
643626786	313	35.87	1	308	18	321	3.0e-69	255	COG0042	tRNA-dihydrouridine synthase	323
643626787	272	31.87	6	272	2	257	4.0e-09	55.8	COG0730	Uncharacterized membrane protein YfcA	258
643626788	479	38.68	1	468	2	433	3.0e-125	442	COG0305	Replicative DNA helicase	435
643626790	232	33.97	11	217	1	201	2.0e-40	158	COG0461	Orotate phosphoribosyltransferase	201
643626791	346	59.13	1	345	1	344	0.0e+00	499	COG0418	Dihydroorotase	344
643626792	304	30.36	1	269	6	260	4.0e-33	135	COG0714	MoxR-like ATPase	329
643626793	398	45.36	1	398	1	392	1.0e-82	300	COG3552	Uncharacterized conserved protein, contains von Willebrand factor type A (vWA) domain	395
643626796	323	37.62	5	323	1	260	2.0e-42	166	COG1975	Xanthine and CO dehydrogenase maturation factor, XdhC/CoxF family	278
643626797	334	22.77	1	331	2	346	7.0e-22	98.4	COG0303	Molybdopterin biosynthesis enzyme	404
643626798	136	64.71	1	136	40	173	1.0e-51	195	COG0290	Translation initiation factor IF-3	176
643626800	268	28.24	16	263	9	266	7.0e-43	167	COG1018	Ferredoxin-NADP reductase	266
643626802	238	40.34	2	226	16	246	8.0e-49	187	COG0175	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme	261
643626803	556	38.16	1	545	1	509	0.0e+00	465	COG0155	Sulfite reductase, beta subunit (hemoprotein)	510
643626805	257	47.84	10	239	2	231	4.0e-56	211	COG0007	Uroporphyrinogen-III methylase (siroheme synthase)	244
643626806	153	40.91	1	153	2	154	2.0e-26	111	COG1522	DNA-binding transcriptional regulator, Lrp family	154
643626807	393	37.63	13	392	30	408	8.0e-65	241	COG2124	Cytochrome P450	411
643626808	249	53.01	5	249	2	250	2.0e-76	279	COG0149	Triosephosphate isomerase	251
643626809	118	46.23	7	110	2	107	2.0e-33	134	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
643626810	120	43.4	15	119	5	110	2.0e-26	110	COG2151	Metal-sulfur cluster biosynthetic enzyme	111
643626814	395	40	105	263	2	157	4.0e-29	122	COG3436	Transposase	157
643626818	348	61.61	7	340	3	337	5.0e-127	447	COG0150	Phosphoribosylaminoimidazole (AIR) synthetase	345
643626819	196	52.13	2	188	1	187	2.0e-63	235	COG0299	Folate-dependent phosphoribosylglycinamide formyltransferase PurN	200
643626820	385	39.67	4	369	1	361	1.0e-82	300	COG0349	Ribonuclease D	361
643626822	146	50.36	7	145	9	144	2.0e-38	151	COG2166	Sulfur transfer protein SufE, Fe-S center assembly	144
643626823	118	35.29	10	111	19	120	2.0e-21	94.6	COG2343	Uncharacterized conserved protein, DUF427 family	132
643626824	598	29.3	150	555	1	383	1.0e-60	228	COG0006	Xaa-Pro aminopeptidase	384
643626825	619	52.55	1	605	11	618	0.0e+00	603	COG4547	Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide:5, 6-dimethylbenzimidazole phosphorib...	620
643626828	344	18.21	36	328	1	289	1.0e-38	154	COG0714	MoxR-like ATPase	329
643626830	85	46.75	5	81	6	79	3.0e-15	73.5	COG0271	Stress-induced morphogen (activity unknown)	90
643626831	719	41.94	191	710	60	543	5.0e-129	455	COG2225	Malate synthase	545
643626832	454	26.92	1	417	2	450	1.0e-47	184	COG0415	Deoxyribodipyrimidine photolyase	461
643626834	867	36.46	17	859	7	858	0.0e+00	574	COG0308	Aminopeptidase N	859
643626836	367	36.54	7	367	3	356	1.0e-69	257	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
643626838	503	52.75	16	502	1	481	0.0e+00	684	COG0064	Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit	483
643626842	143	34.03	1	141	6	149	5.0e-17	80.5	COG1522	DNA-binding transcriptional regulator, Lrp family	154
643626843	381	27.97	17	376	22	394	9.0e-46	177	COG0019	Diaminopimelate decarboxylase	394
643626845	158	26.47	23	158	5	138	1.0e-16	79.3	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
643626846	428	54.07	25	428	1	390	0.0e+00	484	COG0372	Citrate synthase	390
643626847	471	39.21	1	470	2	471	5.0e-118	418	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
643626848	684	25.56	22	465	5	439	2.0e-28	121	COG0658	Predicted membrane metal-binding protein	453
643626849	222	38.91	2	222	10	200	1.0e-46	179	COG1974	SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase)	201
643626850	394	44.97	1	393	6	402	1.0e-94	340	COG0303	Molybdopterin biosynthesis enzyme	404
643626851	159	64.56	1	158	1	157	1.0e-56	212	COG0315	Molybdenum cofactor biosynthesis enzyme	157
643626852	270	52.92	5	261	1	254	1.0e-79	289	COG0134	Indole-3-glycerol phosphate synthase	254
643626853	338	50.59	2	337	1	338	7.0e-104	370	COG0547	Anthranilate phosphoribosyltransferase	338
643626854	195	61.58	1	189	3	191	2.0e-76	278	COG0512	Anthranilate/para-aminobenzoate synthase component II	191
643626855	477	28.21	258	477	15	245	7.0e-17	82.3	COG2861	Uncharacterized conserved protein YibQ, putative polysaccharide deacetylase 2 family	250
643626856	503	47.79	21	493	1	457	0.0e+00	484	COG0147	Anthranilate/para-aminobenzoate synthases component I	462
643626858	662	22.58	3	613	5	635	6.0e-30	126	COG2982	Uncharacterized protein involved in outer membrane biogenesis	648
643626859	207	42.03	1	206	1	169	5.0e-32	130	COG5352	Uncharacterized protein	169
643626861	393	51.28	5	393	17	404	0.0e+00	476	COG4992	Acetylornithine/succinyldiaminopimelate/putrescine aminotransferase	404
643626862	308	51.13	1	307	6	310	2.0e-115	408	COG0078	Ornithine carbamoyltransferase	310
643626864	164	26.49	14	163	2	151	2.0e-15	75.3	COG0782	Transcription elongation factor, GreA/GreB family	151
643626865	158	32.26	13	135	6	125	5.0e-12	63.9	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
643626866	808	38.45	3	807	47	845	0.0e+00	598	COG1643	HrpA-like RNA helicase	845
643626868	333	47.06	10	332	1	320	3.0e-85	308	COG1703	Putative periplasmic protein kinase ArgK or related GTPase of G3E family	323
643626869	84	55.74	1	61	13	73	6.0e-16	75.7	COG0227	Ribosomal protein L28	77
643626871	160	45.07	2	143	3	142	8.0e-28	116	COG2847	Copper(I)-binding protein	151
643626877	363	37.7	7	182	5	183	2.0e-27	117	COG3658	Cytochrome b	192
643626881	68	63.24	1	68	1	67	7.0e-21	92.1	COG1278	Cold shock protein, CspA family	67
643626882	296	32.66	5	296	3	293	5.0e-29	121	COG0583	DNA-binding transcriptional regulator, LysR family	297
643626884	259	34.34	5	254	1	249	4.0e-28	118	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
643626889	395	39.38	105	263	2	157	3.0e-28	120	COG3436	Transposase	157
643626899	259	28.15	3	251	7	270	8.0e-28	117	COG0338	Site-specific DNA-adenine methylase	274
643626917	247	25.61	5	247	7	252	3.0e-06	45.8	COG0730	Uncharacterized membrane protein YfcA	258
643626919	411	25.67	28	395	20	387	4.0e-37	149	COG4695	Phage portal protein BeeE	398
643626921	87	56.47	1	85	1	85	2.0e-20	90.4	COG3811	Uncharacterized protein YjhX, UPF0386 family	85
643626922	552	27.34	10	537	1	527	7.0e-97	348	COG4626	Phage terminase-like protein, large subunit, contains N-terminal HTH domain	546
643626934	131	46.91	50	130	4	84	9.0e-16	75.7	COG3750	Uncharacterized conserved protein, UPF0335 family	85
643626937	313	26.07	49	291	28	282	3.0e-10	59.8	COG4974	Site-specific recombinase XerD	300
643626942	727	63.86	23	686	1	663	0.0e+00	1064	COG0556	Excinuclease UvrABC helicase subunit UvrB	663
643626948	602	66.89	3	602	2	602	0.0e+00	1031	COG0481	Translation elongation factor EF-4, membrane-bound GTPase	603
643626950	1160	61.2	10	1160	7	1149	0.0e+00	1730	COG1038	Pyruvate carboxylase	1149
643626952	786	45.27	33	672	1	649	0.0e+00	614	COG0210	Superfamily I DNA or RNA helicase	655
643626953	381	49.08	3	381	20	400	6.0e-73	268	COG3135	Predicted benzoate:H+ symporter BenE	402
643626955	353	37.32	52	323	1	265	9.0e-52	197	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
643626957	168	28.3	4	162	1	144	3.0e-22	98.4	COG2001	MraZ, DNA-binding transcriptional regulator and inhibitor of RsmH methyltransferase activity	146
643626958	331	51.45	10	310	6	314	3.0e-97	348	COG0275	16S rRNA C1402 N4-methylase RsmH	314
643626960	597	32.35	37	583	5	597	1.0e-97	350	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
643626961	495	39.79	24	484	9	468	6.0e-106	378	COG0769	UDP-N-acetylmuramyl tripeptide synthase	475
643626962	477	44.44	4	468	2	450	4.0e-104	371	COG0770	UDP-N-acetylmuramyl pentapeptide synthase	451
643626963	360	46.84	19	360	1	316	2.0e-56	213	COG0472	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase	319
643626965	465	42.37	3	464	1	446	4.0e-110	391	COG0771	UDP-N-acetylmuramoylalanine-D-glutamate ligase	448
643626966	156	30.08	1	133	4	131	2.0e-19	88.5	COG3791	Uncharacterized conserved protein	133
643626967	156	27.92	6	156	1	149	1.0e-11	62.4	COG3832	Uncharacterized conserved protein YndB, AHSA1/START domain	149
643626968	385	34.33	18	372	10	373	1.0e-62	233	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
643626969	348	36.29	1	346	14	357	8.0e-62	230	COG0707	UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase	357
643626970	470	49.89	6	465	2	457	0.0e+00	549	COG0773	UDP-N-acetylmuramate-alanine ligase	459
643626972	308	41.95	9	302	3	288	9.0e-77	280	COG0812	UDP-N-acetylenolpyruvoylglucosamine reductase	291
643626973	294	41.35	2	291	8	317	5.0e-74	271	COG1181	D-alanine-D-alanine ligase and related ATP-grasp enzymes	317
643626974	308	29.68	76	289	44	258	7.0e-18	85.1	COG1589	Cell division septal protein FtsQ	269
643626975	444	33.49	18	444	2	418	8.0e-89	320	COG0849	Cell division ATPase FtsA	418
643626976	552	55.52	7	341	3	336	1.0e-110	394	COG0206	Cell division GTPase FtsZ	338
643626978	306	47.89	1	282	3	285	6.0e-95	340	COG0774	UDP-3-O-acyl-N-acetylglucosamine deacetylase	300
643626979	278	38.19	7	256	1	253	4.0e-59	221	COG4105	Outer membrane protein assembly factor BamD, BamD/ComL family	254
643626980	546	43.96	1	546	1	553	0.0e+00	505	COG0497	DNA repair ATPase RecN	557
643626982	457	41.89	15	457	8	459	3.0e-82	299	COG0277	FAD/FMN-containing dehydrogenase	459
643626985	232	50.46	4	220	5	222	2.0e-66	245	COG5012	Methanogenic corrinoid protein MtbC1	227
643626986	362	45.33	48	336	6	289	6.0e-75	274	COG1533	DNA repair photolyase	297
643626987	335	36.58	15	295	17	311	5.0e-62	231	COG0646	Methionine synthase I (cobalamin-dependent), methyltransferase domain	311
643626988	106	52.83	1	103	1	104	5.0e-21	92.4	COG5467	Uncharacterized protein	104
643626989	250	45.23	1	236	1	237	2.0e-71	262	COG0152	Phosphoribosylaminoimidazole-succinocarboxamide synthase	247
643626990	79	58.97	1	78	2	79	4.0e-24	102	COG1828	Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component	83
643626991	222	52	1	216	3	227	2.0e-82	298	COG0047	Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain	231
643626992	587	35.18	19	577	4	600	7.0e-100	358	COG4191	Signal transduction histidine kinase regulating C4-dicarboxylate transport system	603
643626993	438	38.26	1	437	5	461	3.0e-108	385	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
643626995	890	47.82	197	607	74	485	3.0e-112	400	COG1530	Ribonuclease G or E	487
643626996	75	40.79	1	75	2	77	4.0e-15	73	COG0425	TusA-related sulfurtransferase	78
643626997	248	47.69	12	226	10	220	1.0e-28	120	COG0785	Cytochrome c biogenesis protein CcdA	220
643627001	464	66.23	2	463	1	462	0.0e+00	752	COG0114	Fumarate hydratase class II	462
643627002	153	45.81	5	153	6	156	6.0e-37	146	COG3814	Uncharacterized protein	157
643627004	354	30.3	7	353	5	362	7.0e-41	161	COG0687	Spermidine/putrescine-binding periplasmic protein	363
643627005	412	27.14	2	412	1	405	1.0e-52	200	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
643627006	471	39.74	5	466	2	457	5.0e-103	368	COG0415	Deoxyribodipyrimidine photolyase	461
643627007	403	49.65	118	401	4	283	4.0e-86	311	COG2230	Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases	283
643627010	344	48.4	3	312	1	300	6.0e-97	347	COG0031	Cysteine synthase	300
643627011	847	27.13	26	800	46	833	2.0e-91	330	COG3264	Small-conductance mechanosensitive channel	835
643627012	239	44.86	1	239	1	236	8.0e-65	240	COG2872	Ser-tRNA(Ala) deacylase AlaX (editing enzyme)	241
643627014	183	22.09	15	182	26	197	6.0e-09	54.1	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
643627015	363	21.08	27	346	44	370	3.0e-20	93.1	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
643627016	268	31.78	15	247	1	233	2.0e-37	149	COG2908	UDP-2,3-diacylglucosamine pyrophosphatase LpxH	237
643627018	441	42.73	9	439	1	425	2.0e-125	442	COG0141	Histidinol dehydrogenase	425
643627019	265	37.85	7	257	10	260	9.0e-46	177	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
643627020	311	37.96	27	297	3	275	3.0e-46	178	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
643627022	365	23.32	1	361	1	353	1.0e-35	144	COG0687	Spermidine/putrescine-binding periplasmic protein	363
643627023	377	47.49	14	368	2	350	5.0e-101	361	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
643627024	254	46.46	9	251	1	251	6.0e-43	167	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
643627028	158	46	8	157	2	150	4.0e-30	124	COG1522	DNA-binding transcriptional regulator, Lrp family	154
643627029	1146	50.46	435	1142	9	769	0.0e+00	725	COG4230	Delta 1-pyrroline-5-carboxylate dehydrogenase	769
643627030	246	40.09	1	206	2	205	4.0e-25	108	COG0705	Membrane associated serine protease, rhomboid family	228
643627032	266	46.88	12	264	5	260	5.0e-69	254	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
643627033	505	32.25	74	504	1	326	8.0e-49	188	COG0306	Phosphate/sulfate permease	326
643627034	301	32.07	3	290	1	286	3.0e-29	122	COG0583	DNA-binding transcriptional regulator, LysR family	297
643627035	288	38.03	3	280	14	291	1.0e-64	239	COG0685	5,10-methylenetetrahydrofolate reductase	291
643627036	181	46.11	3	169	8	173	4.0e-21	94.9	COG1268	Biotin transporter BioY	184
643627037	198	28.77	1	196	2	212	2.0e-09	56.2	COG0619	Energy-coupling factor transporter transmembrane protein EcfT	252
643627038	246	38.68	21	224	15	226	3.0e-46	178	COG1122	Energy-coupling factor transporter ATP-binding protein EcfA2	235
643627039	426	49.65	1	423	15	446	0.0e+00	502	COG0160	4-aminobutyrate aminotransferase or related aminotransferase	447
643627040	372	38.19	13	370	2	349	2.0e-77	283	COG0758	Predicted Rossmann fold nucleotide-binding protein DprA/Smf involved in DNA uptake	350
643627042	884	47.72	1	562	1	554	0.0e+00	608	COG0550	DNA topoisomerase IA	570
643627043	342	47.2	1	339	2	336	2.0e-109	389	COG4175	ABC-type proline/glycine betaine transport system, ATPase component	386
643627044	286	53.9	14	282	7	274	2.0e-87	315	COG4176	ABC-type proline/glycine betaine transport system, permease component	290
643627045	308	43	7	295	10	302	8.0e-72	264	COG2113	ABC-type proline/glycine betaine transport system, periplasmic component	302
643627046	189	26.4	2	176	10	187	7.0e-06	43.9	COG1309	DNA-binding transcriptional regulator, AcrR family	201
643627047	483	47.48	7	478	1	471	0.0e+00	481	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
643627048	548	54.81	2	532	8	541	0.0e+00	499	COG2303	Choline dehydrogenase or related flavoprotein	542
643627049	226	37.04	12	164	20	180	1.0e-21	96.9	COG1525	Endonuclease YncB, thermonuclease family	192
643627050	461	50.6	138	460	1	332	2.0e-103	369	COG3800	Predicted transcriptional regulator	332
643627051	406	24.24	11	402	6	393	4.0e-20	93	COG2814	Predicted arabinose efflux permease, MFS family	394
643627052	117	65.18	4	115	5	116	4.0e-35	140	COG3169	Uncharacterized conserved protein, DUF486 family	116
643627053	546	59.23	36	546	10	526	0.0e+00	724	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component	526
643627058	667	56.95	2	667	1	644	0.0e+00	899	COG4770	Acetyl/propionyl-CoA carboxylase, alpha subunit	645
643627060	709	57.14	576	708	9	141	3.0e-43	170	COG2185	Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding)	143
643627060	709	63.92	6	545	3	548	0.0e+00	749	COG1884	Methylmalonyl-CoA mutase, N-terminal domain/subunit	548
643627062	377	43.78	5	377	2	376	1.0e-91	330	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
643627063	118	52.89	1	118	9	129	8.0e-32	128	COG0509	Glycine cleavage system H protein (lipoate-binding)	131
643627064	956	59.42	8	440	1	446	0.0e+00	602	COG0403	Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain	450
643627064	956	60.41	451	924	19	496	0.0e+00	691	COG1003	Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain	496
643627065	733	36.45	1	213	3	198	2.0e-30	128	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
643627065	733	43.79	326	613	2	290	1.0e-81	297	COG1250	3-hydroxyacyl-CoA dehydrogenase	307
643627066	403	39.52	1	403	1	392	6.0e-73	268	COG0183	Acetyl-CoA acetyltransferase	392
643627067	128	32.2	2	114	14	131	1.0e-18	85.5	COG3791	Uncharacterized conserved protein	133
643627068	591	33.65	39	456	11	393	4.0e-65	242	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
643627069	132	40.32	7	128	1	122	3.0e-13	67.5	COG0789	DNA-binding transcriptional regulator, MerR family	124
643627070	126	32.2	6	121	1	117	2.0e-11	61.3	COG0789	DNA-binding transcriptional regulator, MerR family	124
643627071	163	31.65	1	139	5	140	5.0e-19	87.4	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
643627072	168	24.52	13	166	4	139	1.0e-12	66.2	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
643627073	444	30.66	8	439	10	445	7.0e-53	201	COG0534	Na+-driven multidrug efflux pump	455
643627075	306	32.75	8	291	1	255	4.0e-16	78.9	COG0730	Uncharacterized membrane protein YfcA	258
643627076	266	44.98	2	265	1	262	5.0e-62	231	COG0005	Purine nucleoside phosphorylase	262
643627077	322	53.11	1	322	1	304	9.0e-77	280	COG1079	ABC-type uncharacterized transport system, permease component	304
643627078	361	42.94	1	346	8	344	3.0e-69	255	COG4603	ABC-type uncharacterized transport system, permease component	356
643627079	525	54.76	16	517	2	501	0.0e+00	625	COG3845	ABC-type uncharacterized transport system, ATPase component	501
643627080	331	45.07	2	327	14	344	2.0e-72	266	COG1744	Basic membrane lipoprotein Med, periplasmic binding protein (PBP1-ABC) superfamily	345
643627081	130	32.33	4	129	47	176	8.0e-15	72.7	COG0456	Ribosomal protein S18 acetylase RimI and related acetyltransferases	177
643627082	202	37.33	7	194	3	219	3.0e-28	118	COG1214	tRNA A37 threonylcarbamoyladenosine modification protein TsaB	220
643627083	186	50.63	108	184	6	84	1.0e-24	106	COG0694	Fe-S cluster biogenesis protein NfuA, 4Fe-4S-binding domain	93
643627085	287	30.22	10	285	5	282	7.0e-49	187	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
643627089	293	29.9	8	292	13	301	2.0e-44	173	COG1560	Lauroyl/myristoyl acyltransferase	308
643627090	343	27.25	12	341	10	337	2.0e-29	123	COG1536	Flagellar motor switch protein FliG	339
643627092	434	51.37	1	434	1	438	0.0e+00	526	COG0015	Adenylosuccinate lyase	438
643627093	84	50.68	12	83	12	83	6.0e-13	65.8	COG3042	Putative hemolysin	85
643627094	1048	39.31	17	1017	3	1009	0.0e+00	855	COG0841	Multidrug efflux pump subunit AcrB	1009
643627095	388	30.7	58	377	28	369	3.0e-20	93.3	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
643627097	694	54.09	9	665	6	671	0.0e+00	770	COG1523	Pullulanase/glycogen debranching enzyme	697
643627098	382	33.6	1	359	22	386	8.0e-67	247	COG0448	ADP-glucose pyrophosphorylase	393
643627100	1170	33.98	950	1147	13	214	5.0e-34	140	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
643627100	1170	38.01	211	477	1	268	7.0e-64	239	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
643627104	485	39	287	480	6	202	9.0e-40	158	COG1573	Uracil-DNA glycosylase	202
643627105	406	57.99	3	406	1	404	0.0e+00	540	COG4277	Predicted DNA-binding protein with the Helix-hairpin-helix motif	404
643627106	337	22.6	3	308	13	362	4.0e-18	85.8	COG1680	CubicO group peptidase, beta-lactamase class C family	390
643627107	155	30	15	134	3	122	2.0e-12	65.7	COG1846	DNA-binding transcriptional regulator, MarR family	126
643627108	368	42.94	16	352	6	341	6.0e-70	258	COG1566	Multidrug resistance efflux pump	352
643627111	261	35.34	13	258	10	253	6.0e-47	181	COG0566	tRNA G18 (ribose-2'-O)-methylase SpoU	260
643627112	148	54.01	12	148	5	138	6.0e-41	159	COG1832	Predicted CoA-binding protein	140
643627113	103	50.55	4	94	1	91	6.0e-21	92.2	COG0140	Phosphoribosyl-ATP pyrophosphohydrolase	92
643627114	253	69.02	1	252	1	255	2.0e-109	388	COG0107	Imidazole glycerol phosphate synthase subunit HisF	256
643627115	239	49.58	1	238	2	239	1.0e-77	282	COG0106	Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase	241
643627116	126	36.59	7	126	46	162	7.0e-14	69.6	COG4731	Uncharacterized conserved protein, DUF2147 family	162
643627117	213	46.95	1	213	1	204	3.0e-69	254	COG0118	Imidazoleglycerol phosphate synthase glutamine amidotransferase subunit HisH	204
643627118	195	65.64	1	195	3	195	2.0e-82	298	COG0131	Imidazoleglycerol phosphate dehydratase HisB	195
643627119	674	36.15	10	672	7	690	0.0e+00	537	COG0480	Translation elongation factor EF-G, a GTPase	697
643627120	406	25.84	49	402	51	394	2.0e-13	71	COG2814	Predicted arabinose efflux permease, MFS family	394
643627121	242	25.29	4	234	24	282	1.0e-05	43.5	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
643627122	262	28.01	4	259	5	282	2.0e-23	102	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
643627123	325	45.85	1	323	6	327	6.0e-87	314	COG1171	Threonine dehydratase	347
643627124	274	26.15	4	273	3	282	1.0e-13	70.9	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
643627125	595	41.57	18	592	1	567	1.0e-130	460	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
643627126	629	34.74	25	579	10	533	1.0e-91	330	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
643627127	145	58.62	1	145	1	145	7.0e-55	206	COG1490	D-Tyr-tRNAtyr deacylase	145
643627128	306	30.09	1	305	1	300	4.0e-33	135	COG0524	Sugar or nucleoside kinase, ribokinase family	311
643627129	319	35.02	20	293	8	247	2.0e-60	226	COG0152	Phosphoribosylaminoimidazole-succinocarboxamide synthase	247
643627130	145	52.48	1	140	13	153	2.0e-22	98.8	COG1238	Uncharacterized membrane protein YqaA, SNARE-associated domain	161
643627132	369	34.87	1	293	1	304	7.0e-61	227	COG4260	Membrane protease subunit, stomatin/prohibitin family, contains C-terminal Zn-ribbon domain	345
643627136	396	31.45	18	382	16	382	6.0e-54	205	COG3853	Uncharacterized conserved protein YaaN involved in tellurite resistance	386
643627138	491	45.22	6	229	1	230	1.0e-61	230	COG1187	16S rRNA U516 pseudouridylate synthase RsuA and related 23S rRNA U2605, pseudouridylate synthases	248
643627140	144	57.55	1	138	12	150	5.0e-41	160	COG0590	tRNA(Arg) A34 adenosine deaminase TadA	152
643627141	230	34.22	1	214	7	230	3.0e-33	135	COG2220	L-ascorbate metabolism protein UlaG, beta-lactamase superfamily	258
643627143	95	44.21	1	95	1	95	5.0e-23	99.1	COG0721	Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit	96
643627144	491	52.11	1	487	2	473	0.0e+00	473	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
643627146	223	37.44	3	193	26	236	6.0e-42	164	COG3023	N-acetyl-anhydromuramyl-L-alanine amidase AmpD	257
643627147	404	30.32	1	401	9	435	4.0e-49	188	COG1541	Phenylacetate-coenzyme A ligase PaaK, adenylate-forming domain family	438
643627148	276	52.87	11	254	1	237	4.0e-78	284	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
643627149	429	18.64	15	391	1	357	1.0e-16	81.7	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
643627150	358	29.09	22	350	1	314	9.0e-38	151	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
643627151	329	29.5	8	328	5	297	3.0e-33	136	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
643627152	274	47.41	21	271	3	250	7.0e-86	310	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
643627153	653	31.96	9	613	17	611	9.0e-119	421	COG1022	Long-chain acyl-CoA synthetase (AMP-forming)	613
643627156	235	38.33	5	228	1	225	1.0e-44	173	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
643627157	392	36.16	3	178	1	177	4.0e-31	129	COG2059	Chromate transport protein ChrA	195
643627159	206	48.08	1	205	1	205	5.0e-55	207	COG0522	Ribosomal protein S4 or related protein	205
643627160	361	39.78	6	359	1	353	2.0e-88	319	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
643627161	311	42.55	6	286	5	279	3.0e-69	255	COG0287	Prephenate dehydrogenase	279
643627162	287	28.83	22	285	43	296	7.0e-28	117	COG3921	Uncharacterized conserved protein	300
643627163	331	25.22	4	327	19	338	2.0e-16	80	COG4093	Uncharacterized protein	338
643627164	182	48.3	3	177	10	183	3.0e-46	178	COG3703	Cation transport regulator ChaC	190
643627166	525	26.83	321	525	41	243	2.0e-25	111	COG1360	Flagellar motor protein MotB	244
643627167	771	47.71	4	755	2	785	0.0e+00	858	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
643627168	255	29.27	11	228	22	252	4.0e-17	81.8	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
643627171	186	37.08	6	183	2	178	4.0e-31	128	COG0712	FoF1-type ATP synthase, delta subunit	178
643627172	512	66.8	1	512	1	501	0.0e+00	801	COG0056	FoF1-type ATP synthase, alpha subunit	504
643627173	289	44.48	5	289	1	286	2.0e-86	312	COG0224	FoF1-type ATP synthase, gamma subunit	287
643627174	475	75.32	5	473	2	468	0.0e+00	797	COG0055	FoF1-type ATP synthase, beta subunit	468
643627175	132	30.4	4	126	3	126	3.0e-16	77.2	COG0355	FoF1-type ATP synthase, epsilon subunit	135
643627176	336	54.97	1	321	2	314	1.0e-104	373	COG0462	Phosphoribosylpyrophosphate synthetase	314
643627177	341	39.94	1	341	2	338	7.0e-79	287	COG2008	Threonine aldolase	342
643627178	134	58.33	1	132	20	148	7.0e-43	166	COG2983	Uncharacterized cysteine cluster protein YcgN, CxxCxxCC family	153
643627179	306	44.01	1	304	1	303	5.0e-86	311	COG0196	FAD synthase	304
643627180	147	36.91	5	145	10	158	4.0e-21	94	COG2030	Acyl dehydratase	159
643627181	297	30.59	8	260	1	237	2.0e-47	182	COG0647	Ribonucleotide monophosphatase NagD, HAD superfamily	269
643627182	305	40.13	1	303	3	304	1.0e-60	226	COG1227	Inorganic pyrophosphatase/exopolyphosphatase	311
643627184	328	30.82	38	328	17	299	6.0e-42	164	COG3735	Uncharacterized conserved protein YbaP, TraB family	299
643627185	95	63.83	1	94	1	94	3.0e-31	126	COG0234	Co-chaperonin GroES (HSP10)	96
643627186	547	50.27	1	534	1	523	0.0e+00	517	COG0459	Chaperonin GroEL (HSP60 family)	524
643627187	191	41.77	37	188	12	168	1.0e-36	146	COG3807	SH3-like domain	171
643627188	312	45.86	2	310	15	324	2.0e-90	325	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
643627189	272	50	1	272	2	279	8.0e-90	323	COG0656	Aldo/keto reductase, related to diketogulonate reductase	280
643627191	413	32.31	8	413	6	381	2.0e-32	133	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
643627192	381	43.31	5	381	2	377	2.0e-115	409	COG1454	Alcohol dehydrogenase, class IV	377
643627193	462	36.82	5	459	16	469	1.0e-101	363	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
643627194	459	35.7	5	458	1	443	5.0e-111	395	COG0174	Glutamine synthetase	443
643627195	345	21.23	4	335	3	346	4.0e-26	112	COG4663	TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component	363
643627196	441	32.44	1	440	2	447	4.0e-63	235	COG4664	TRAP-type mannitol/chloroaromatic compound transport system, large permease component	447
643627197	168	29.7	3	165	2	166	2.0e-21	95.7	COG4665	TRAP-type mannitol/chloroaromatic compound transport system, small permease component	182
643627198	259	48.36	12	254	12	255	4.0e-67	247	COG3931	Predicted N-formylglutamate amidohydrolase	263
643627199	288	29.23	4	283	3	281	7.0e-46	177	COG1737	DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains	281
643627200	379	39.51	21	379	14	374	8.0e-72	264	COG0772	Bacterial cell division protein FtsW, lipid II flippase	381
643627201	648	31.41	3	603	1	585	8.0e-116	411	COG0768	Cell division protein FtsI/penicillin-binding protein 2	599
643627203	300	30.69	11	279	5	279	3.0e-38	152	COG1792	Cell shape-determining protein MreC	284
643627204	345	60.18	4	341	1	339	2.0e-121	428	COG1077	Actin-like ATPase involved in cell morphogenesis	342
643627206	529	50.12	12	422	1	409	1.0e-116	413	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
643627208	152	35.59	3	118	11	128	8.0e-18	83.2	COG3794	Plastocyanin	128
643627209	244	28.51	11	231	51	285	1.0e-25	110	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
643627210	355	24.09	11	339	62	404	6.0e-24	105	COG2132	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)	451
643627211	508	38.35	160	292	7	139	2.0e-19	90.4	COG4642	Uncharacterized conserved protein	139
643627212	564	31.66	15	268	3	259	4.0e-39	156	COG0388	Predicted amidohydrolase	274
643627212	564	40.07	274	551	5	268	1.0e-67	251	COG0171	NH3-dependent NAD+ synthetase	268
643627213	308	34.3	2	308	6	309	5.0e-54	204	COG1105	Fructose-1-phosphate kinase or kinase (PfkB)	310
643627214	197	28.85	1	197	2	207	4.0e-25	107	COG0655	Multimeric flavodoxin WrbA	207
643627219	455	33.26	30	455	3	436	7.0e-116	411	COG0621	tRNA A37 methylthiotransferase MiaB	437
643627220	392	27.3	8	390	5	388	2.0e-59	222	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
643627221	167	36.91	12	156	6	149	3.0e-18	85	COG2236	Hypoxanthine phosphoribosyltransferase	192
643627222	204	33.82	1	202	1	204	3.0e-18	85.3	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
643627223	274	62.93	3	261	1	259	6.0e-113	400	COG0623	Enoyl-[acyl-carrier-protein] reductase (NADH)	259
643627224	200	52.31	7	200	22	214	9.0e-65	239	COG0259	Pyridoxine/pyridoxamine 5'-phosphate oxidase	214
643627225	180	36.92	103	167	1	65	2.0e-11	62.1	COG1278	Cold shock protein, CspA family	67
643627226	153	42.74	25	141	11	126	3.0e-29	121	COG1430	Uncharacterized conserved membrane protein, UPF0127 family	126
643627228	260	30.57	21	249	2	228	1.0e-39	156	COG2188	DNA-binding transcriptional regulator, GntR family	236
643627229	254	37.99	8	234	3	227	5.0e-36	144	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
643627230	218	38.86	13	218	9	219	5.0e-47	180	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
643627231	320	29.47	1	312	6	314	9.0e-31	127	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
643627232	502	46.45	6	495	9	500	0.0e+00	535	COG1129	ABC-type sugar transport system, ATPase component	500
643627233	336	38.41	22	332	4	310	3.0e-38	152	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
643627234	325	40.78	19	324	11	312	4.0e-41	162	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
643627235	316	30.67	5	312	1	311	5.0e-39	155	COG0524	Sugar or nucleoside kinase, ribokinase family	311
643627236	248	44.8	1	245	4	250	2.0e-43	169	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
643627237	472	47.03	6	467	2	463	3.0e-120	425	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
643627238	389	24.32	16	383	22	389	7.0e-07	48.7	COG2814	Predicted arabinose efflux permease, MFS family	394
643627241	481	45.62	1	481	6	488	0.0e+00	540	COG0397	Uncharacterized conserved protein YdiU, UPF0061 family	488
643627242	396	48.58	7	390	3	388	1.0e-114	406	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
643627243	341	35.69	1	340	1	350	1.0e-65	243	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
643627244	420	23.6	64	412	75	411	4.0e-26	112	COG2124	Cytochrome P450	411
643627246	710	56.29	23	523	2	496	0.0e+00	693	COG0753	Catalase	496
643627248	184	51.35	8	184	11	195	9.0e-49	186	COG2094	3-methyladenine DNA glycosylase Mpg	200
643627253	165	28.17	7	147	4	145	3.0e-23	101	COG3871	General stress protein 26 (function unknown)	145
643627256	364	47.37	11	344	7	331	7.0e-113	400	COG0182	Methylthioribose-1-phosphate isomerase (methionine salvage pathway), a paralog of eIF-2B alpha subunit	346
643627257	144	54.61	1	139	1	138	1.0e-37	148	COG5319	Uncharacterized protein	142
643627259	182	38.85	32	182	8	161	3.0e-41	161	COG0386	Glutathione peroxidase, house-cleaning role in reducing lipid peroxides	162
643627260	375	28.04	13	322	4	317	6.0e-58	218	COG0123	Acetoin utilization deacetylase AcuC or a related deacetylase	340
643627261	193	40	2	181	1	180	5.0e-27	114	COG1514	2'-5' RNA ligase	180
643627263	407	33.67	1	384	2	397	3.0e-71	262	COG1519	3-deoxy-D-manno-octulosonic-acid transferase	419
643627264	347	45.17	3	324	5	356	9.0e-85	307	COG1858	Cytochrome c peroxidase	364
643627266	339	38.33	4	339	16	361	9.0e-68	250	COG0687	Spermidine/putrescine-binding periplasmic protein	363
643627267	266	42.32	1	266	1	263	8.0e-55	207	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
643627268	297	43.73	3	297	1	285	7.0e-64	237	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
643627269	354	52.92	2	354	1	352	2.0e-117	415	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
643627270	495	34.85	9	477	8	474	5.0e-82	298	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
643627271	611	28.48	1	611	1	608	1.0e-79	291	COG4206	Outer membrane cobalamin receptor protein	608
643627272	286	24.9	22	267	48	306	1.0e-22	100	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
643627273	329	44.41	1	326	2	331	3.0e-45	175	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
643627274	250	42.8	2	247	1	257	1.0e-63	236	COG1120	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	258
643627275	219	29.65	12	207	8	195	7.0e-16	77.7	COG1865	Adenosylcobinamide amidohydrolase	200
643627276	575	32.57	129	434	37	336	1.0e-35	144	COG0642	Signal transduction histidine kinase	336
643627278	322	46	10	307	25	288	3.0e-74	272	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
643627279	298	39.86	6	292	59	338	2.0e-68	252	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
643627281	606	36.82	23	606	11	597	0.0e+00	521	COG1164	Oligoendopeptidase F	598
643627282	533	33.26	106	524	28	442	2.0e-59	223	COG1793	ATP-dependent DNA ligase	444
643627283	383	22.68	6	331	18	425	2.0e-34	140	COG1236	RNA processing exonuclease, beta-lactamase fold, Cft2 family	427
643627284	472	58.33	7	472	12	478	0.0e+00	639	COG2308	Uncharacterized conserved protein, circularly permuted ATPgrasp superfamily	488
643627285	316	36.31	1	311	1	307	1.0e-67	250	COG2307	Uncharacterized conserved protein, Alpha-E superfamily	313
643627286	269	33.68	1	260	11	298	1.0e-29	124	COG1305	Transglutaminase-like enzyme, putative cysteine protease	319
643627287	241	44.77	1	239	1	236	4.0e-66	244	COG3484	Predicted proteasome-type protease	255
643627288	290	31.49	2	282	21	294	2.0e-37	149	COG2267	Lysophospholipase, alpha-beta hydrolase superfamily	298
643627292	98	45.45	5	92	7	93	9.0e-20	88.4	COG1188	Ribosomal 50S subunit-recycling heat shock protein, contains S4 domain	100
643627293	112	42.42	4	65	5	68	3.0e-08	50.6	COG1146	NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit	68
643627294	169	50	5	168	1	164	1.0e-46	179	COG1329	RNA polymerase-interacting regulator, CarD/CdnL/TRCF family	166
643627295	249	42.19	15	248	8	242	6.0e-27	114	COG0368	Cobalamin synthase	246
643627296	338	47.31	10	337	2	335	2.0e-70	259	COG2038	NaMN:DMB phosphoribosyltransferase	347
643627297	622	34.94	1	409	4	397	8.0e-55	208	COG0475	Kef-type K+ transport system, membrane component KefB	397
643627299	230	44.34	21	228	33	243	6.0e-45	174	COG2968	Uncharacterized conserved protein YggE, contains kinase-interacting SIMPL domain	243
643627300	430	58.22	3	428	2	426	0.0e+00	600	COG2873	O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent	426
643627303	305	43.85	19	277	1	256	5.0e-70	257	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
643627304	152	42.96	7	141	14	148	9.0e-33	132	COG0835	Chemotaxis signal transduction protein	165
643627305	686	36.12	1	675	4	708	0.0e+00	537	COG0643	Chemotaxis protein histidine kinase CheA	716
643627309	792	39.31	466	758	91	408	3.0e-50	193	COG0840	Methyl-accepting chemotaxis protein	408
643627311	560	31.96	170	493	44	406	2.0e-33	137	COG0840	Methyl-accepting chemotaxis protein	408
643627315	1102	33.88	679	1099	43	431	7.0e-64	239	COG3281	Predicted trehalose synthase	438
643627315	1102	35.06	29	532	1	505	5.0e-96	346	COG0366	Glycosidase	505
643627316	713	59.34	90	712	1	628	0.0e+00	781	COG0296	1,4-alpha-glucan branching enzyme	628
643627317	688	51.08	1	684	8	689	0.0e+00	814	COG1523	Pullulanase/glycogen debranching enzyme	697
643627318	592	36.21	16	521	39	561	1.0e-119	423	COG0296	1,4-alpha-glucan branching enzyme	628
643627319	605	34.07	68	603	8	519	2.0e-97	350	COG1640	4-alpha-glucanotransferase	520
643627320	871	43.4	4	870	5	888	0.0e+00	756	COG3280	Maltooligosyltrehalose synthase	889
643627321	221	27.23	6	206	4	205	8.0e-22	97.2	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
643627322	487	53.13	14	471	1	453	0.0e+00	604	COG0034	Glutamine phosphoribosylpyrophosphate amidotransferase	470
643627323	204	28.65	4	174	1	164	1.0e-14	73.4	COG1286	Uncharacterized membrane protein, required for colicin V production	182
643627324	452	57.3	1	450	1	455	0.0e+00	601	COG1066	Predicted ATP-dependent serine protease	456
643627327	248	52.21	1	246	8	255	7.0e-86	310	COG1127	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, ATPase component MlaF	263
643627328	260	43.36	3	258	8	263	5.0e-57	214	COG0767	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, permease component MlaE	267
643627329	349	41.62	1	344	2	358	4.0e-90	324	COG0787	Alanine racemase	360
643627331	245	47.24	2	243	1	251	3.0e-45	175	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
643627332	77	62.67	1	75	3	77	4.0e-12	63	COG0236	Acyl carrier protein	80
643627333	420	57.24	1	418	2	411	0.0e+00	472	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
643627334	392	35.92	10	380	13	342	9.0e-85	307	COG1559	Cell division protein YceG, involved in septum cleavage	342
643627336	432	54.32	28	432	29	410	8.0e-106	377	COG5323	Large terminase phage packaging protein	410
643627337	393	39.33	7	387	3	381	2.0e-79	289	COG4695	Phage portal protein BeeE	398
643627339	185	32.45	22	158	22	168	4.0e-20	91.2	COG3740	Phage head maturation protease	194
643627340	398	38.18	21	398	39	421	1.0e-75	277	COG4653	Predicted phage phi-C31 gp36 major capsid-like protein	422
643627342	111	24.53	4	109	7	107	4.0e-08	50	COG5614	Bacteriophage head-tail adaptor	109
643627344	137	44.85	1	136	1	136	6.0e-36	143	COG5437	Predicted secreted protein	138
643627348	213	51.89	29	213	1	184	2.0e-57	216	COG5448	Uncharacterized protein	184
643627349	294	42.5	14	173	10	169	5.0e-37	148	COG5449	Uncharacterized protein	225
643627352	258	55.43	74	257	5	188	3.0e-64	238	COG1045	Serine acetyltransferase	194
643627353	442	46.28	1	441	1	402	4.0e-97	348	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
643627354	457	56.79	134	456	1	323	0.0e+00	485	COG0022	Pyruvate/2-oxoglutarate/acetoin dehydrogenase complex, dehydrogenase (E1) component	324
643627355	329	51.82	3	329	15	343	6.0e-112	397	COG1071	TPP-dependent pyruvate or acetoin dehydrogenase subunit alpha	358
643627357	309	31.03	25	305	1	257	5.0e-35	141	COG1830	Fructose-bisphosphate aldolase class Ia, DhnA family	265
643627358	397	55.05	4	395	5	390	0.0e+00	469	COG0126	3-phosphoglycerate kinase	395
643627359	169	39.16	10	166	1	158	2.0e-40	158	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
643627360	197	41.94	52	197	9	158	2.0e-41	162	COG0652	Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family	158
643627361	416	47.22	6	416	2	401	9.0e-121	427	COG0162	Tyrosyl-tRNA synthetase	401
643627362	385	39.74	17	379	1	371	8.0e-66	244	COG2377	1,6-Anhydro-N-acetylmuramate kinase	371
643627363	140	52.17	3	132	6	141	1.0e-36	145	COG3542	Predicted sugar epimerase, cupin superfamily	162
643627365	425	67.45	1	424	1	421	0.0e+00	648	COG0148	Enolase	423
643627367	137	46.97	1	132	4	135	3.0e-34	137	COG0735	Fe2+ or Zn2+ uptake regulation protein	145
643627369	1218	19.26	7	729	2	584	3.0e-66	247	COG0209	Ribonucleotide reductase alpha subunit	696
643627370	296	33.8	15	296	1	280	4.0e-36	145	COG0157	Nicotinate-nucleotide pyrophosphorylase	280
643627371	603	53.55	1	603	1	597	0.0e+00	739	COG0449	Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains	597
643627372	456	49.67	6	440	1	456	0.0e+00	534	COG1207	Bifunctional protein GlmU, N-acetylglucosamine-1-phosphate-uridyltransferase/glucosamine-1-phosphate-acetyltransferase	460
643627373	229	29.77	10	223	5	216	7.0e-32	130	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
643627374	152	48.39	1	148	1	153	3.0e-53	200	COG3045	Periplasmic catabolite regulation protein CreA (function unknown)	165
643627375	385	46.37	6	382	1	386	2.0e-92	332	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
643627376	203	44.34	6	203	2	213	4.0e-42	164	COG3047	Outer membrane protein W	213
643627377	534	45.15	11	534	1	526	0.0e+00	616	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component	526
643627378	646	55.96	1	643	1	645	0.0e+00	732	COG4770	Acetyl/propionyl-CoA carboxylase, alpha subunit	645
643627380	262	38.13	1	256	3	256	2.0e-37	149	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
643627381	121	53.72	1	121	1	121	1.0e-29	121	COG0838	NADH:ubiquinone oxidoreductase subunit 3 (chain A)	123
643627382	174	70.7	18	174	12	168	3.0e-77	280	COG0377	NADH:ubiquinone oxidoreductase 20 kD subunit (chhain B) or related Fe-S oxidoreductase	194
643627383	200	46.07	1	177	2	176	7.0e-45	173	COG0852	NADH:ubiquinone oxidoreductase 27 kD subunit (chain C)	176
643627384	404	60.2	14	404	9	398	0.0e+00	609	COG0649	NADH:ubiquinone oxidoreductase 49 kD subunit (chain D)	398
643627385	303	43.83	12	173	2	160	4.0e-50	191	COG1905	NADH:ubiquinone oxidoreductase 24 kD subunit (chain E)	160
643627387	431	59.1	1	421	5	424	0.0e+00	640	COG1894	NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F)	424
643627389	673	47.29	4	673	1	690	0.0e+00	645	COG1034	NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)	693
643627391	349	50.9	7	335	2	329	6.0e-93	334	COG1005	NADH:ubiquinone oxidoreductase subunit 1 (chain H)	332
643627392	167	46.3	11	167	5	161	8.0e-46	176	COG1143	Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)	172
643627393	136	33.08	5	134	3	123	4.0e-10	57.3	COG0599	Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family	124
643627394	199	47.9	2	168	7	166	3.0e-26	111	COG0839	NADH:ubiquinone oxidoreductase subunit 6 (chain J)	166
643627395	101	63.37	1	101	1	100	6.0e-24	102	COG0713	NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K)	100
643627396	716	49.3	4	494	3	474	4.0e-124	438	COG1009	NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit	606
643627397	513	55.53	4	495	5	484	0.0e+00	525	COG1008	NADH:ubiquinone oxidoreductase subunit 4 (chain M)	497
643627398	478	46.03	2	476	1	475	6.0e-98	351	COG1007	NADH:ubiquinone oxidoreductase subunit 2 (chain N)	475
643627399	242	36.51	6	242	1	235	9.0e-44	170	COG0340	Biotin-(acetyl-CoA carboxylase) ligase	238
643627400	257	41.9	1	253	1	251	4.0e-62	231	COG1521	Pantothenate kinase type III	251
643627401	557	37.05	9	551	12	554	3.0e-118	419	COG0595	mRNA degradation ribonuclease J1/J2	555
643627403	524	40.25	1	479	28	505	2.0e-109	389	COG0513	Superfamily II DNA and RNA helicase	513
643627404	534	52.1	9	531	4	527	0.0e+00	719	COG4108	Peptide chain release factor RF-3	528
643627405	259	34.62	3	253	1	249	7.0e-28	117	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
643627406	364	38.25	6	362	1	352	3.0e-91	328	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
643627408	158	33.71	1	89	1	89	9.0e-11	60	COG1826	Sec-independent protein translocase protein TatA	94
643627409	289	36.8	7	275	1	252	9.0e-54	203	COG0805	Sec-independent protein secretion pathway component TatC	255
643627410	279	57.04	4	279	11	285	5.0e-105	374	COG2607	Predicted ATPase, AAA+ superfamily	287
643627411	387	26.04	162	387	1	265	4.0e-17	82.5	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
643627412	219	48	21	219	10	208	8.0e-57	213	COG2518	Protein-L-isoaspartate O-methyltransferase	209
643627413	261	40.23	1	261	1	252	3.0e-65	242	COG0496	Broad specificity polyphosphatase and 5'/3'-nucleotidase SurE	252
643627414	203	41.67	1	202	36	225	2.0e-55	208	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
643627416	429	24.93	22	378	23	391	2.0e-11	64.4	COG3307	O-antigen ligase	424
643627417	260	23.44	12	254	24	278	2.0e-32	132	COG2273	Beta-glucanase, GH16 family	355
643627424	626	21.26	1	525	1	520	9.0e-40	158	COG0367	Asparagine synthetase B (glutamine-hydrolyzing)	542
643627426	618	25.46	20	608	4	567	2.0e-73	270	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
643627428	789	29.79	24	500	8	458	2.0e-56	214	COG3206	Uncharacterized protein involved in exopolysaccharide biosynthesis	458
643627428	789	33.91	555	781	27	251	1.0e-34	142	COG0489	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster	265
643627429	326	17.86	5	269	4	277	4.0e-09	55.9	COG1216	Glycosyltransferase, GT2 family	305
643627430	329	24.66	1	276	1	287	6.0e-18	85.2	COG1216	Glycosyltransferase, GT2 family	305
643627432	297	52.31	1	280	14	291	4.0e-101	360	COG1210	UTP-glucose-1-phosphate uridylyltransferase	291
643627433	271	30.07	1	257	1	293	4.0e-24	105	COG0451	Nucleoside-diphosphate-sugar epimerase	314
643627434	278	41.9	3	258	50	333	2.0e-50	192	COG5597	Alpha-N-acetylglucosamine transferase	368
643627435	404	25.62	1	357	1	301	4.0e-30	125	COG0451	Nucleoside-diphosphate-sugar epimerase	314
643627436	189	38.1	5	182	2	187	2.0e-25	108	COG0693	Putative intracellular protease/amidase	188
643627437	345	24.46	30	338	15	336	5.0e-33	135	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
643627438	263	29.35	26	223	9	203	4.0e-26	112	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
643627439	252	21.47	57	216	50	211	1.0e-08	53.7	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
643627441	193	25.37	30	163	8	133	4.0e-17	81.6	COG3791	Uncharacterized conserved protein	133
643627442	376	65.69	1	376	1	366	0.0e+00	551	COG1062	Zn-dependent alcohol dehydrogenase	366
643627443	142	51.59	3	128	11	135	6.0e-32	130	COG3474	Cytochrome c2	135
643627444	600	31.74	31	600	154	773	0.0e+00	542	COG4993	Glucose dehydrogenase	773
643627446	271	23.86	4	254	10	261	2.0e-13	69.7	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
643627449	320	28.1	22	313	44	343	2.0e-30	126	COG3391	DNA-binding beta-propeller fold protein YncE	381
643627452	242	42.79	7	226	3	224	2.0e-55	209	COG1131	ABC-type multidrug transport system, ATPase component	293
643627453	286	29.07	52	274	52	275	5.0e-09	55.3	COG0842	ABC-type multidrug transport system, permease component	286
643627455	347	28.43	99	292	30	226	6.0e-13	68.7	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
643627456	268	36.49	1	147	1	148	9.0e-23	100	COG5501	Predicted secreted protein	148
643627457	275	34.45	64	272	3	208	2.0e-37	149	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
643627458	366	36.49	6	359	13	379	2.0e-56	213	COG3287	Uncharacterized conserved protein, contains FIST_N domain	379
643627459	477	32.45	49	307	75	336	2.0e-32	134	COG0642	Signal transduction histidine kinase	336
643627462	260	52.26	6	245	4	242	6.0e-79	287	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
643627463	326	25.33	1	292	9	305	4.0e-15	75.6	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
643627464	245	41.15	1	241	13	255	4.0e-34	138	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
643627465	230	50.22	9	229	3	225	1.0e-61	229	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
643627466	241	43.1	1	231	3	234	5.0e-43	167	COG0704	Phosphate uptake regulator	240
643627467	265	66.01	13	265	3	253	4.0e-126	444	COG1117	ABC-type phosphate transport system, ATPase component	253
643627468	449	41.96	197	449	45	292	6.0e-62	231	COG0581	ABC-type phosphate transport system, permease component	292
643627469	481	46.2	182	480	11	310	2.0e-72	266	COG0573	ABC-type phosphate transport system, permease component	310
643627470	347	22.83	1	331	12	318	2.0e-35	143	COG0226	ABC-type phosphate transport system, periplasmic component	318
643627471	225	35.92	19	217	23	225	1.0e-32	133	COG2135	Putative SOS response-associated peptidase YedK	226
643627472	121	38.14	25	120	4	100	4.0e-10	56.7	COG0640	DNA-binding transcriptional regulator, ArsR family	110
643627473	166	38.71	12	159	5	159	3.0e-26	111	COG1853	NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family	176
643627474	344	27.33	14	344	4	322	3.0e-58	219	COG0598	Mg2+ and Co2+ transporter CorA	322
643627475	358	26.82	179	357	20	182	2.0e-27	116	COG0717	Deoxycytidine triphosphate deaminase	183
643627478	101	39.78	6	98	1	93	8.0e-25	105	COG0776	Bacterial nucleoid DNA-binding protein	94
643627479	318	58.39	2	318	6	322	2.0e-110	392	COG0332	3-oxoacyl-[acyl-carrier-protein] synthase III	323
643627480	370	45.99	14	349	1	333	1.0e-96	346	COG0416	Fatty acid/phospholipid biosynthesis enzyme	338
643627481	54	58.14	1	43	15	57	5.0e-11	59.5	COG0333	Ribosomal protein L32	57
643627483	138	29.46	11	122	36	146	6.0e-13	67	COG2913	Outer membrane protein assembly factor BamE, lipoprotein component of the BamABCDE complex	147
643627484	134	52.76	10	134	4	130	4.0e-50	190	COG0229	Peptide methionine sulfoxide reductase MsrB	140
643627485	252	27.31	4	252	31	288	1.0e-17	83.9	COG3176	Putative hemolysin	292
643627486	379	44.08	15	374	1	352	1.0e-113	403	COG0482	tRNA U34 2-thiouridine synthase MnmA/TrmU, contains the PP-loop ATPase domain	356
643627488	232	37.67	2	219	7	228	3.0e-51	195	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
643627489	704	52.66	10	702	2	667	0.0e+00	851	COG0272	NAD-dependent DNA ligase	667
643627490	695	50.07	3	666	2	663	0.0e+00	775	COG1200	RecG-like helicase	677
643627492	146	25.9	4	141	1	139	9.0e-20	89.7	COG0822	NifU homolog involved in Fe-S cluster formation	150
643627493	119	65	8	106	11	110	3.0e-43	167	COG0139	Phosphoribosyl-AMP cyclohydrolase	111
643627495	444	59.23	1	443	2	436	0.0e+00	634	COG1206	Folate-dependent tRNA-U54 methylase TrmFO/GidA	439
643627496	920	50.51	14	901	1	804	0.0e+00	951	COG0188	DNA gyrase/topoisomerase IV, subunit A	804
643627497	87	61.63	2	87	5	90	3.0e-33	133	COG5425	Usg protein (tryptophan operon, function unknown)	90
643627498	308	36.72	1	302	20	305	1.0e-52	200	COG0010	Arginase family enzyme	305
643627499	656	53.23	1	648	1	648	0.0e+00	617	COG1138	Cytochrome c biogenesis factor	648
643627500	151	43.24	3	150	7	151	9.0e-35	139	COG3088	Cytochrome c-type biogenesis protein CcmH/NrfF	153
643627501	258	41.02	1	253	2	256	6.0e-47	181	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
643627502	186	55.7	28	185	4	159	2.0e-46	178	COG0440	Acetolactate synthase, small subunit	163
643627503	588	49.73	9	569	2	549	0.0e+00	644	COG0028	Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme	550
643627504	305	47.25	1	305	10	318	2.0e-46	179	COG0530	Ca2+/Na+ antiporter	320
643627505	280	51.04	1	240	1	241	2.0e-76	279	COG2935	Arginyl-tRNA--protein-N-Asp/Glu arginylyltransferase	253
643627508	156	21.94	3	156	1	154	2.0e-16	78.8	COG2606	Cys-tRNA(Pro) deacylase, prolyl-tRNA editing enzyme YbaK/EbsC	155
643627509	941	34	16	868	21	914	0.0e+00	592	COG1391	Glutamine synthetase adenylyltransferase	963
643627511	212	50.73	9	212	5	209	2.0e-54	205	COG0800	2-keto-3-deoxy-6-phosphogluconate aldolase	211
643627512	601	40.73	9	599	4	570	0.0e+00	585	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
643627514	396	37.63	6	395	1	393	1.0e-78	287	COG1092	23S rRNA G2069 N7-methylase RlmK or C1962 C5-methylase RlmI	393
643627517	394	61.52	1	394	1	392	0.0e+00	529	COG3825	Uncharacterized conserved protein,  contains von Willebrand factor type A (vWA) domain	393
643627521	279	26.39	6	277	23	296	3.0e-35	142	COG0714	MoxR-like ATPase	329
643627522	140	55	20	139	1	120	1.0e-23	102	COG1734	RNA polymerase-binding transcription factor DksA	120
643627523	396	29.67	9	389	1	387	3.0e-41	162	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
643627524	132	31.71	1	123	21	141	4.0e-16	77	COG2050	Acyl-coenzyme A thioesterase PaaI, contains HGG motif	141
643627525	268	49.43	10	267	1	260	2.0e-86	312	COG0708	Exonuclease III	261
643627526	108	53.85	7	108	7	110	2.0e-32	130	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
643627528	358	44.76	2	358	29	410	8.0e-101	360	COG0232	dGTP triphosphohydrolase	412
643627529	322	30.39	11	309	1	303	5.0e-47	182	COG1295	Uncharacterized membrane protein, BrkB/YihY/UPF0761 family (not an RNase)	303
643627530	380	34.83	9	380	7	376	1.0e-57	217	COG1454	Alcohol dehydrogenase, class IV	377
643627531	493	58.42	1	492	4	495	0.0e+00	721	COG0554	Glycerol kinase	499
643627533	565	19.92	45	509	21	432	9.0e-19	88.9	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
643627534	90	65.17	3	90	9	97	8.0e-19	85.1	COG5477	Predicted small integral membrane protein	97
643627535	259	34.85	1	259	17	280	3.0e-47	181	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
643627536	290	32.19	1	289	4	295	2.0e-48	185	COG1175	ABC-type sugar transport system, permease component	295
643627537	361	38.18	1	349	1	338	2.0e-91	329	COG3839	ABC-type sugar transport system, ATPase component	338
643627538	362	37.82	1	349	2	338	1.0e-85	310	COG3839	ABC-type sugar transport system, ATPase component	338
643627539	532	44.55	12	528	14	518	0.0e+00	467	COG0578	Glycerol-3-phosphate dehydrogenase	532
643627542	781	57.85	1	777	1	773	0.0e+00	945	COG4993	Glucose dehydrogenase	773
643627546	135	27.5	22	134	6	125	3.0e-06	44.5	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
643627547	234	32.26	1	217	14	221	1.0e-28	120	COG1285	Uncharacterized membrane protein YhiD, involved in acid resistance	221
643627549	877	32.12	86	523	1	432	5.0e-68	253	COG1793	ATP-dependent DNA ligase	444
643627549	877	51.84	577	846	3	274	5.0e-83	302	COG3285	Eukaryotic-type DNA primase	299
643627551	155	36.25	1	154	21	180	8.0e-28	116	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
643627552	322	52.58	13	322	2	310	3.0e-86	312	COG0331	Malonyl CoA-acyl carrier protein transacylase	310
643627553	76	46.43	11	66	6	60	4.0e-09	53.1	COG3313	Predicted Fe-S protein YdhL, DUF1289 family	74
643627554	160	50	17	151	2	137	6.0e-36	143	COG0816	RNase H-fold protein, predicted Holliday junction resolvase in Firmicutes and mycoplasms, involved in anti-termination at Rho-dependent terminators	141
643627555	417	27.39	5	317	2	287	3.0e-27	116	COG4235	Cytochrome c-type biogenesis protein CcmH/NrfG	287
643627557	415	26.9	29	405	1	387	4.0e-51	195	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
643627559	107	44.09	1	91	1	90	5.0e-20	89.2	COG4311	Sarcosine oxidase delta subunit	97
643627560	993	39.03	601	991	2	377	2.0e-92	334	COG0404	Glycine cleavage system T protein (aminomethyltransferase)	379
643627561	159	29.22	2	152	38	186	2.0e-11	62.3	COG4583	Sarcosine oxidase gamma subunit	189
643627562	629	36.7	1	363	12	386	2.0e-48	187	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
643627563	199	49.75	1	199	2	198	9.0e-66	242	COG0605	Superoxide dismutase	204
643627564	157	34.18	2	156	40	196	8.0e-27	113	COG1611	Predicted Rossmann fold nucleotide-binding protein	205
643627565	428	17.72	174	426	12	264	2.0e-07	51.1	COG1652	Nucleoid-associated protein YgaU, contains BON and LysM domains	269
643627566	595	63.78	89	584	1	497	0.0e+00	662	COG5265	ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components	497
643627567	215	28.71	5	205	4	211	3.0e-13	68.5	COG4649	Uncharacterized protein	221
643627568	448	23.14	62	445	11	358	6.0e-24	105	COG1520	Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat	370
643627569	487	45.32	1	470	2	444	0.0e+00	525	COG1160	Predicted GTPases	444
643627570	655	42.04	334	641	3	266	1.0e-75	278	COG4608	ABC-type oligopeptide transport system, ATPase component	309
643627570	655	47.65	1	313	1	315	2.0e-98	354	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
643627571	384	34.51	43	380	17	281	1.0e-39	157	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
643627572	341	32.34	5	341	3	316	2.0e-59	223	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
643627573	522	25.93	1	521	6	553	8.0e-61	228	COG0747	ABC-type transport system, periplasmic component	556
643627575	328	42.29	50	320	6	283	5.0e-69	254	COG0324	tRNA A37 N6-isopentenylltransferase MiaA	308
643627576	235	59.32	1	235	3	238	8.0e-89	320	COG0528	Uridylate kinase	238
643627577	188	48.65	5	188	3	187	2.0e-56	212	COG0233	Ribosome recycling factor	187
643627578	247	52.79	12	244	13	245	5.0e-76	277	COG0020	Undecaprenyl pyrophosphate synthase	245
643627579	273	31.06	13	263	1	263	2.0e-29	123	COG0575	CDP-diglyceride synthetase	265
643627580	394	47.93	1	385	1	378	3.0e-124	438	COG0743	1-deoxy-D-xylulose 5-phosphate reductoisomerase	385
643627581	444	31.19	13	443	1	371	3.0e-42	166	COG0750	Membrane-associated protease RseP, regulator of RpoE activity	375
643627583	777	32.65	1	777	1	766	0.0e+00	508	COG4775	Outer membrane protein assembly factor BamA	766
643627584	230	19.41	5	172	4	169	2.0e-07	49.2	COG2825	Periplasmic chaperone for outer membrane proteins, Skp family	170
643627585	155	51.39	10	151	3	144	3.0e-41	160	COG0764	3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase	147
643627586	260	52.16	1	254	3	257	1.0e-87	316	COG1043	Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase	260
643627587	273	39.1	7	268	8	273	4.0e-51	195	COG3494	Uncharacterized conserved protein, DUF1009 family	279
643627588	379	42.82	1	379	2	381	5.0e-102	364	COG0763	Lipid A disaccharide synthetase	381
643627589	607	37.45	5	503	2	529	6.0e-130	458	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
643627591	200	19.46	35	200	16	199	3.0e-06	45.4	COG3637	Opacity protein and related surface antigens	199
643627592	149	39.74	1	148	3	153	8.0e-25	106	COG1522	DNA-binding transcriptional regulator, Lrp family	154
643627593	204	22.5	1	196	1	196	5.0e-07	47.9	COG1279	Arginine exporter protein ArgO	202
643627594	153	27.83	42	153	1	115	7.0e-14	69.9	COG2315	Predicted DNA-binding protein with ?double-wing? structural motif, MmcQ/YjbR family	118
643627595	519	43.11	3	507	1	464	0.0e+00	517	COG0215	Cysteinyl-tRNA synthetase	464
643627596	559	35.71	22	440	1	407	2.0e-94	339	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
643627598	255	25	1	254	8	287	5.0e-13	68.5	COG1562	Phytoene/squalene synthetase	288
643627600	209	36.68	1	208	54	282	5.0e-34	137	COG0122	3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase	285
643627601	220	29.22	1	219	1	207	6.0e-29	120	COG0400	Predicted esterase	207
643627602	209	36.05	48	191	1	146	2.0e-24	106	COG1403	5-methylcytosine-specific restriction endonuclease McrA	146
643627603	245	34.29	88	222	4	134	2.0e-23	103	COG0394	Protein-tyrosine-phosphatase	139
643627607	108	36.56	10	102	19	109	3.0e-10	57.1	COG0640	DNA-binding transcriptional regulator, ArsR family	110
643627609	345	51.88	1	345	6	341	1.0e-91	329	COG0798	Arsenite efflux pump ArsB, ACR3 family	342
643627610	237	29.59	29	221	1	184	3.0e-33	135	COG0431	NAD(P)H-dependent FMN reductase	184
643627612	483	52.76	5	481	2	482	0.0e+00	615	COG0364	Glucose-6-phosphate 1-dehydrogenase	483
643627613	223	31.74	1	223	1	230	2.0e-39	155	COG0363	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase	238
643627614	533	46.73	37	524	1	445	0.0e+00	482	COG0166	Glucose-6-phosphate isomerase	446
643627615	115	34.43	1	115	7	128	2.0e-26	111	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
643627616	315	27.86	26	301	11	284	2.0e-38	153	COG2897	3-mercaptopyruvate sulfurtransferase SseA, contains two rhodanese domains	285
643627619	418	23.56	10	416	17	397	4.0e-37	149	COG2133	Glucose/arabinose dehydrogenase, beta-propeller fold	399
643627620	198	39.08	103	189	13	99	2.0e-14	72.7	COG2863	Cytochrome c553	121
643627626	415	16.54	25	391	15	372	2.0e-06	47.7	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
643627629	673	38.31	3	672	1	612	0.0e+00	516	COG3894	Uncharacterized 2Fe-2 and 4Fe-4S clusters-containing protein, contains DUF4445 domain	614
643627631	323	21.28	40	305	17	284	3.0e-19	89.7	COG0685	5,10-methylenetetrahydrofolate reductase	291
643627634	229	47.62	12	220	3	204	1.0e-60	226	COG0293	23S rRNA U2552 (ribose-2'-O)-methylase RlmE/FtsJ	205
643627635	188	37.22	9	188	6	184	4.0e-35	141	COG3108	Uncharacterized conserved protein YcbK, DUF882 family	185
643627636	518	38.32	34	500	81	544	1.0e-91	331	COG2989	Murein L,D-transpeptidase YcbB/YkuD	561
643627637	363	35.98	4	356	5	338	3.0e-61	229	COG1044	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase	338
643627639	399	42.89	2	399	6	411	1.0e-104	373	COG0304	3-oxoacyl-(acyl-carrier-protein) synthase	412
643627640	211	25.31	33	194	21	176	5.0e-13	68.1	COG5342	Invasion protein IalB, involved in pathogenesis	181
643627641	488	57.53	2	476	14	487	0.0e+00	673	COG0753	Catalase	496
643627642	308	33.78	3	294	1	290	2.0e-22	100	COG0583	DNA-binding transcriptional regulator, LysR family	297
643627643	173	54.88	2	164	13	165	2.0e-57	215	COG0678	Peroxiredoxin	165
643627644	243	38.72	1	222	4	235	3.0e-32	131	COG0580	Glycerol uptake facilitator and related aquaporins (Major Intrinsic Protein Family)	241
643627645	320	61.87	15	313	9	306	0.0e+00	470	COG0320	Lipoate synthase	306
643627646	296	31.65	154	290	18	148	9.0e-12	64.6	COG2010	Cytochrome c, mono- and diheme variants	150
643627647	140	45.08	18	139	29	146	2.0e-16	78.1	COG3909	Cytochrome c556	147
643627648	186	55.11	6	181	1	175	1.0e-61	229	COG0634	Hypoxanthine-guanine phosphoribosyltransferase	178
643627649	134	46.97	1	132	17	144	3.0e-36	144	COG2867	Ribosome association toxin PasT (RatA) of the RatAB toxin-antitoxin module	146
643627650	236	55.56	5	228	2	220	6.0e-80	290	COG0036	Pentose-5-phosphate-3-epimerase	220
643627651	394	28.32	5	386	4	385	7.0e-37	148	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
643627652	298	52.44	1	298	2	296	7.0e-82	297	COG0264	Translation elongation factor EF-Ts	296
643627653	253	55.42	5	253	1	249	5.0e-100	357	COG0052	Ribosomal protein S2	252
643627654	295	30.72	6	290	2	289	2.0e-16	79.9	COG0524	Sugar or nucleoside kinase, ribokinase family	311
643627655	303	60.6	1	302	7	308	3.0e-101	361	COG2313	Pseudouridine-5'-phosphate glycosidase (pseudoU degradation)	310
643627656	265	41.44	9	263	1	251	6.0e-46	177	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
643627659	569	26.91	3	568	37	557	3.0e-69	256	COG4166	ABC-type oligopeptide transport system, periplasmic component	562
643627661	1088	32.66	2	1029	1	1009	0.0e+00	790	COG0841	Multidrug efflux pump subunit AcrB	1009
643627663	213	22.28	1	184	4	186	1.0e-08	53.5	COG1309	DNA-binding transcriptional regulator, AcrR family	201
643627664	214	43.93	1	212	5	218	5.0e-53	200	COG2761	Predicted dithiol-disulfide isomerase, DsbA family	225
643627665	405	20	15	402	9	387	1.0e-12	68.3	COG2814	Predicted arabinose efflux permease, MFS family	394
643627666	1168	44.84	6	1155	8	1139	0.0e+00	1242	COG1197	Transcription-repair coupling factor (superfamily II helicase)	1139
643627668	334	60.19	8	330	5	327	0.0e+00	479	COG0113	Delta-aminolevulinic acid dehydratase, porphobilinogen synthase	330
643627670	296	49.82	10	294	1	285	1.0e-79	290	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
643627671	823	31.63	10	803	6	756	2.0e-111	397	COG2366	Acyl-homoserine lactone (AHL) acylase PvdQ	768
643627672	447	46.29	44	447	12	409	2.0e-105	376	COG2262	50S ribosomal subunit-associated GTPase HflX	411
643627673	70	61.76	1	68	7	74	4.0e-26	109	COG1923	sRNA-binding regulator protein Hfq	77
643627674	500	25.7	10	500	13	488	4.0e-34	139	COG0168	Trk-type K+ transport system, membrane component	499
643627675	458	31.47	1	231	1	225	9.0e-39	155	COG0569	Trk K+ transport system, NAD-binding component	225
643627676	476	42.98	1	448	4	456	1.0e-124	440	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
643627677	749	40.45	25	729	8	707	0.0e+00	557	COG5000	Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation	712
643627678	456	37.27	1	454	2	463	3.0e-99	355	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
643627679	357	41.04	5	346	15	356	2.0e-81	296	COG3852	Signal transduction histidine kinase, nitrogen specific	363
643627680	317	43.77	1	309	9	318	1.0e-77	283	COG0042	tRNA-dihydrouridine synthase	323
643627681	225	42.29	1	222	3	229	3.0e-54	205	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	230
643627682	159	57.96	3	159	1	157	1.0e-59	221	COG0245	2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	159
643627683	165	37.42	5	156	18	159	5.0e-17	80.7	COG1267	Phosphatidylglycerophosphatase A	160
643627684	161	54.19	1	154	8	160	3.0e-40	157	COG1546	Nicotinamide mononucleotide (NMN) deamidase PncC	162
643627685	392	49.01	1	392	1	403	3.0e-127	448	COG2081	Predicted flavoprotein YhiN	408
643627688	202	55.28	4	202	2	198	4.0e-69	254	COG2109	ATP:corrinoid adenosyltransferase	198
643627689	406	34.9	4	383	15	390	8.0e-42	165	COG3213	Uncharacterized protein involved in response to NO	396
643627692	345	37.75	7	342	1	319	6.0e-71	261	COG0523	GTPase, G3E family	323
643627694	209	51.22	2	205	1	203	2.0e-53	202	COG2082	Precorrin isomerase	210
643627695	244	41.91	2	240	1	234	6.0e-56	210	COG2243	Precorrin-2 methylase	234
643627696	239	51.48	2	237	7	242	5.0e-76	277	COG1010	Precorrin-3B methylase	249
643627697	247	47.44	1	225	3	235	6.0e-55	207	COG2099	Precorrin-6x reductase	257
643627698	387	37.56	5	195	1	197	5.0e-34	138	COG2241	Precorrin-6B methylase 1	210
643627698	387	46.74	215	387	3	186	4.0e-42	165	COG2242	Precorrin-6B methylase 2	187
643627700	260	55.78	1	249	3	252	2.0e-93	335	COG2875	Precorrin-4 methylase	254
643627701	241	48.5	1	232	2	231	1.0e-58	219	COG0007	Uroporphyrinogen-III methylase (siroheme synthase)	244
643627702	254	25.3	1	245	1	234	1.0e-28	119	COG2243	Precorrin-2 methylase	234
643627704	370	50.27	6	369	4	360	4.0e-116	411	COG0337	3-dehydroquinate synthetase	360
643627705	181	40.96	6	171	2	167	8.0e-49	186	COG0703	Shikimate kinase	172
643627708	311	45.75	6	309	5	300	3.0e-84	305	COG4974	Site-specific recombinase XerD	300
643627709	442	47.02	15	433	7	418	2.0e-128	453	COG4536	Mg2+ and Co2+ transporter CorB, contains DUF21, CBS pair, and CorC-HlyC domains	423
643627712	513	50.29	2	512	12	525	0.0e+00	614	COG5598	Trimethylamine:corrinoid methyltransferase	526
643627713	195	30.46	2	194	15	204	6.0e-25	107	COG3218	ABC-type uncharacterized transport system, auxiliary component	205
643627714	321	25	1	316	1	307	2.0e-22	99.8	COG1463	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic component MlaD	359
643627715	257	52.92	1	257	3	259	4.0e-95	340	COG1127	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, ATPase component MlaF	263
643627716	356	44.92	96	351	12	262	4.0e-59	222	COG0767	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, permease component MlaE	267
643627718	168	39.89	2	165	6	183	2.0e-35	141	COG3658	Cytochrome b	192
643627720	792	65.19	2	767	13	782	0.0e+00	1144	COG0466	ATP-dependent Lon protease, bacterial type	782
643627721	362	41.29	1	362	2	362	3.0e-96	345	COG1902	2,4-dienoyl-CoA reductase or related NADH-dependent reductase, Old Yellow Enzyme (OYE) family	363
643627722	401	59.56	32	397	1	366	0.0e+00	527	COG0343	Queuine/archaeosine tRNA-ribosyltransferase	372
643627723	1025	40.47	2	1006	1	1008	0.0e+00	916	COG0841	Multidrug efflux pump subunit AcrB	1009
643627724	395	30.16	4	359	4	368	1.0e-24	107	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
643627727	645	36.35	17	642	10	606	1.0e-110	394	COG3284	Transcriptional regulator of acetoin/glycerol metabolism	606
643627728	364	39.66	1	347	4	337	8.0e-75	274	COG1064	D-arabinose 1-dehydrogenase, Zn-dependent alcohol dehydrogenase family	339
643627729	543	37.04	1	530	2	523	3.0e-89	322	COG0459	Chaperonin GroEL (HSP60 family)	524
643627731	340	27.16	32	322	1	291	5.0e-29	122	COG2159	Predicted metal-dependent hydrolase, TIM-barrel fold	293
643627734	365	26.37	23	109	11	100	7.0e-11	62	COG0633	Ferredoxin	102
643627734	365	30.41	122	337	9	207	1.0e-33	137	COG0543	NAD(P)H-flavin reductase	252
643627741	424	34.16	1	403	2	443	1.0e-78	287	COG1508	DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog	444
643627742	482	29.56	270	471	15	170	7.0e-30	125	COG0516	IMP dehydrogenase/GMP reductase	170
643627743	324	25	24	281	10	277	7.0e-10	58.4	COG1275	Tellurite resistance protein TehA and related permeases	329
643627744	369	52.84	1	352	1	335	5.0e-116	411	COG3839	ABC-type sugar transport system, ATPase component	338
643627745	373	41.41	148	373	55	281	3.0e-52	199	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
643627746	330	33.33	45	330	5	292	3.0e-49	189	COG1175	ABC-type sugar transport system, permease component	295
643627747	450	19.04	48	447	29	427	4.0e-18	86.6	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
643627749	440	40.22	8	432	4	444	3.0e-106	379	COG2723	Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase	460
643627750	317	34.29	8	316	9	319	8.0e-56	210	COG0837	Glucokinase	320
643627751	261	36.43	1	261	1	279	1.0e-45	176	COG1319	CO or xanthine dehydrogenase, FAD-binding subunit	284
643627752	790	39.31	7	790	6	731	0.0e+00	613	COG1529	CO or xanthine dehydrogenase, Mo-binding subunit	731
643627753	160	56.29	1	151	2	152	4.0e-56	210	COG2080	Aerobic-type carbon monoxide dehydrogenase, small subunit, CoxS/CutS family	156
643627754	176	41.38	1	144	1	143	1.0e-27	116	COG3427	Carbon monoxide dehydrogenase subunit G	146
643627755	733	32.58	335	598	74	336	6.0e-33	136	COG0642	Signal transduction histidine kinase	336
643627756	390	34.14	27	384	14	379	5.0e-54	205	COG3287	Uncharacterized conserved protein, contains FIST_N domain	379
643627757	226	36.19	12	221	4	211	1.0e-38	153	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
643627758	544	34.49	1	530	3	524	0.0e+00	527	COG0033	Phosphoglucomutase	524
643627759	673	52.6	2	664	33	689	0.0e+00	768	COG1523	Pullulanase/glycogen debranching enzyme	697
643627760	468	45.95	1	468	6	480	2.0e-128	453	COG0297	Glycogen synthase	487
643627761	410	51.74	1	402	7	386	0.0e+00	499	COG0448	ADP-glucose pyrophosphorylase	393
643627763	801	44.89	6	796	2	749	0.0e+00	778	COG0058	Glucan phosphorylase	750
643627764	144	36.43	1	139	1	139	3.0e-27	114	COG1959	DNA-binding transcriptional regulator, IscR family	150
643627765	137	33.33	1	118	1	120	5.0e-21	93.7	COG0789	DNA-binding transcriptional regulator, MerR family	124
643627766	781	50.14	47	773	2	709	0.0e+00	680	COG2217	Cation transport ATPase	713
643627767	66	23.53	1	65	3	70	1.0e-08	51.2	COG2608	Copper chaperone CopZ	71
643627769	140	63.43	2	135	1	134	9.0e-53	199	COG0105	Nucleoside diphosphate kinase	135
643627770	615	44.99	1	516	3	527	0.0e+00	509	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
643627771	206	47.26	1	201	1	198	1.0e-33	136	COG2095	Small neutral amino acid transporter SnatA, MarC family	203
643627772	191	32.68	1	191	12	215	3.0e-29	121	COG3577	Predicted aspartyl protease	215
643627773	162	36.05	14	157	4	144	2.0e-21	95.4	COG2927	DNA polymerase III, chi subunit	144
643627774	489	43.63	20	488	11	485	2.0e-124	439	COG0260	Leucyl aminopeptidase	485
643627775	364	26.87	1	351	13	364	5.0e-25	108	COG0795	Lipopolysaccharide export LptBFGC system, permease protein LptF	364
643627776	364	26.98	1	364	2	364	1.0e-37	150	COG0795	Lipopolysaccharide export LptBFGC system, permease protein LptF	364
643627777	714	25	4	684	22	739	8.0e-64	238	COG1452	LPS assembly outer membrane protein LptD (organic solvent tolerance protein OstA)	784
643627778	405	18.15	6	293	2	291	1.0e-08	55.1	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
643627779	322	54.29	4	321	5	329	2.0e-103	369	COG1995	4-hydroxy-L-threonine phosphate dehydrogenase PdxA	332
643627780	278	44.66	18	278	1	256	8.0e-72	263	COG0030	16S rRNA A1518 and A1519 N6-dimethyltransferase RsmA/KsgA/DIM1 (may also have DNA glycosylase/AP lyase activity)	259
643627782	278	46.59	1	275	1	276	6.0e-55	207	COG2890	Methylase of polypeptide chain release factors	280
643627783	351	61	1	350	3	361	0.0e+00	488	COG0216	Protein chain release factor A	363
643627786	321	38.33	28	313	3	300	3.0e-58	218	COG0010	Arginase family enzyme	305
643627787	388	48.33	1	383	2	388	6.0e-116	411	COG1473	Metal-dependent amidase/aminoacylase/carboxypeptidase	392
643627789	336	28.57	39	335	1	299	4.0e-44	172	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
643627790	313	54.19	4	313	2	310	2.0e-113	402	COG1957	Inosine-uridine nucleoside N-ribohydrolase	311
643627793	397	37.53	1	395	2	396	2.0e-93	336	COG0626	Cystathionine beta-lyase/cystathionine gamma-synthase	396
643627794	172	58.14	1	172	3	174	9.0e-59	219	COG0663	Carbonic anhydrase or acetyltransferase, isoleucine patch superfamily	176
643627795	211	57.07	2	192	1	188	9.0e-69	253	COG0194	Guanylate kinase	191
643627796	296	41.41	1	296	1	290	6.0e-65	241	COG1561	Uncharacterized conserved protein YicC, UPF0701 family	290
643627798	457	63.6	2	445	1	443	0.0e+00	686	COG3200	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase, class II	445
643627799	337	49.54	9	332	2	328	4.0e-98	351	COG4977	Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain	328
643627800	394	32.92	13	324	1	315	7.0e-34	138	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
643627801	244	42.49	2	234	21	250	5.0e-69	254	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
643627802	236	47.68	3	236	1	237	8.0e-76	276	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
643627803	336	33.86	18	336	13	295	2.0e-36	146	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
643627804	431	28.29	85	431	6	308	3.0e-21	96.4	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
643627805	199	36.6	1	191	2	191	2.0e-22	99.6	COG2068	CTP:molybdopterin cytidylyltransferase MocA	199
643627808	154	31.85	1	153	10	166	6.0e-13	67	COG1495	Disulfide bond formation protein DsbB	170
643627809	228	31.14	5	228	9	236	6.0e-36	144	COG2188	DNA-binding transcriptional regulator, GntR family	236
643627810	455	26.99	1	442	3	421	3.0e-51	196	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
643627811	395	42.75	7	395	14	400	1.0e-87	317	COG1228	Imidazolonepropionase or related amidohydrolase	406
643627812	507	60.61	3	496	5	496	0.0e+00	560	COG2986	Histidine ammonia-lyase	498
643627813	560	75.89	1	560	3	558	0.0e+00	945	COG2987	Urocanate hydratase	561
643627818	211	46.29	15	185	6	179	1.0e-42	166	COG1386	Chromosome segregation and condensation protein ScpB	184
643627819	262	34.16	20	260	2	240	3.0e-39	155	COG1354	Chromatin segregation and condensation protein Rec8/ScpA/Scc1, kleisin family	248
643627820	337	32.65	8	331	7	341	7.0e-53	201	COG1472	Periplasmic beta-glucosidase and related glycosidases	397
643627822	580	38.03	1	579	1	577	0.0e+00	522	COG0018	Arginyl-tRNA synthetase	577
643627825	151	42.57	5	150	4	151	8.0e-35	139	COG2332	Cytochrome c-type biogenesis protein CcmE	153
643627826	342	43.71	1	342	1	349	9.0e-95	340	COG0002	N-acetyl-gamma-glutamylphosphate reductase	349
643627827	266	31.48	1	266	10	264	5.0e-50	191	COG0796	Glutamate racemase	269
643627828	1128	29.79	19	688	4	634	0.0e+00	517	COG4231	TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit	640
643627829	297	34.65	1	294	1	297	2.0e-35	143	COG0583	DNA-binding transcriptional regulator, LysR family	297
643627831	720	50.07	6	708	14	734	0.0e+00	836	COG0046	Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain	743
643627832	80	31.82	1	80	1	85	1.0e-12	64.6	COG0271	Stress-induced morphogen (activity unknown)	90
643627833	121	49.52	2	105	1	105	5.0e-38	149	COG0278	Glutaredoxin-related protein	105
643627834	124	31.62	1	117	1	105	2.0e-07	47.6	COG3027	Cell division protein ZapA, inhibits GTPase activity of FtsZ	105
643627837	672	52.71	19	671	12	662	0.0e+00	846	COG0021	Transketolase	663
643627839	351	49.83	30	328	4	294	4.0e-71	262	COG2354	Uncharacterized membrane protein MutK, may be involved in DNA repair	303
643627840	333	61.26	2	331	1	332	0.0e+00	463	COG0057	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase	335
643627842	166	53.37	4	166	1	159	6.0e-54	203	COG0669	Phosphopantetheine adenylyltransferase	159
643627844	297	29.9	1	290	1	297	3.0e-28	119	COG0583	DNA-binding transcriptional regulator, LysR family	297
643627845	499	39.05	5	486	2	472	2.0e-119	422	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
643627846	218	28.64	10	205	10	213	2.0e-22	99.1	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
643627848	974	67.27	26	968	3	935	0.0e+00	1571	COG0178	Excinuclease UvrABC ATPase subunit	935
643627849	388	23.89	32	385	37	390	1.0e-08	54.8	COG2814	Predicted arabinose efflux permease, MFS family	394
643627850	468	45.37	7	457	2	453	0.0e+00	464	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
643627851	191	54.4	1	182	5	182	1.0e-47	183	COG3803	Uncharacterized conserved protein, DUF924 family	182
643627852	418	19.22	6	381	13	393	4.0e-07	49.4	COG2814	Predicted arabinose efflux permease, MFS family	394
643627853	346	53.74	1	344	1	344	2.0e-123	435	COG0809	S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase)	348
643627855	153	59.48	1	153	3	155	1.0e-54	205	COG1225	Peroxiredoxin	157
643627856	447	32.16	185	437	10	258	7.0e-34	138	COG0739	Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contain LysM domain	277
643627857	146	35.58	19	120	23	126	5.0e-17	80.4	COG1664	Cytoskeletal protein CcmA, bactofilin family	146
643627858	217	39.81	8	213	70	277	9.0e-31	126	COG5473	Uncharacterized membrane protein	290
643627860	375	64.02	126	363	1	239	1.0e-95	343	COG1186	Protein chain release factor B	239
643627861	848	44.72	1	790	2	765	0.0e+00	806	COG5009	Membrane carboxypeptidase/penicillin-binding protein	797
643627862	389	27.02	133	376	15	227	3.0e-32	133	COG0860	N-acetylmuramoyl-L-alanine amidase	231
643627863	383	37.82	4	382	1	393	7.0e-84	304	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
643627864	247	28.4	3	246	1	244	1.0e-25	110	COG1651	Protein-disulfide isomerase	244
643627865	377	58.45	12	372	1	361	0.0e+00	492	COG0821	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase IspG/GcpE	361
643627866	404	21.1	26	331	4	274	4.0e-16	79.4	COG1426	Cytoskeletal protein RodZ, contains Xre-like HTH and DUF4115 domains	284
643627867	435	45.23	29	423	1	388	1.0e-115	410	COG0156	7-keto-8-aminopelargonate synthetase or related enzyme	388
643627870	470	28.08	16	470	1	408	4.0e-60	225	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
643627874	310	37.68	18	290	6	276	8.0e-58	217	COG1741	Redox-sensitive bicupin YhaK, pirin superfamily	276
643627875	518	41.54	4	192	1	190	1.0e-46	181	COG0518	GMP synthase - Glutamine amidotransferase domain	198
643627875	518	69.91	200	518	1	315	0.0e+00	553	COG0519	GMP synthase, PP-ATPase domain/subunit	315
643627877	372	20.5	45	372	83	440	2.0e-25	110	COG2067	Long-chain fatty acid transport protein	440
643627878	321	25.37	34	301	23	276	3.0e-06	46.4	COG5006	Threonine/homoserine efflux transporter RhtA	292
643627880	305	50.17	1	302	1	303	5.0e-127	447	COG1897	Homoserine trans-succinylase	307
643627881	288	29.75	12	282	4	279	6.0e-20	91.7	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
643627882	294	55.74	35	269	36	270	3.0e-85	308	COG2326	Polyphosphate kinase 2, PPK2 family	270
643627883	205	27.64	1	199	3	201	9.0e-10	57	COG1309	DNA-binding transcriptional regulator, AcrR family	201
643627884	365	50.83	5	365	1	351	8.0e-111	393	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
643627885	268	41.96	7	260	14	267	7.0e-50	190	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
643627886	286	46.18	1	286	1	286	6.0e-60	224	COG1176	ABC-type spermidine/putrescine transport system, permease component I	287
643627887	467	30.57	14	458	2	453	1.0e-67	251	COG1167	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain	459
643627888	75	48.21	19	74	8	63	5.0e-07	46.1	COG5457	Uncharacterized conserved protein YjiS, DUF1127 family	63
643627889	235	42.05	62	234	1	176	1.0e-38	153	COG4420	Uncharacterized membrane protein	191
643627890	160	59.38	33	160	3	130	1.0e-45	175	COG0103	Ribosomal protein S9	130
643627891	154	56.76	1	148	1	148	2.0e-55	208	COG0102	Ribosomal protein L13	148
643627894	177	44	1	175	1	172	2.0e-50	191	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase or related enzyme	173
643627895	449	41.52	1	444	1	438	2.0e-121	429	COG4091	Predicted homoserine dehydrogenase, contains C-terminal SAF domain	438
643627896	351	26.35	4	306	2	308	4.0e-31	129	COG0451	Nucleoside-diphosphate-sugar epimerase	314
643627898	332	29.5	1	259	3	260	5.0e-33	135	COG0300	Short-chain dehydrogenase	265
643627899	521	54.29	30	520	4	499	0.0e+00	588	COG0427	Acyl-CoA hydrolase	501
643627903	239	36.68	7	232	18	244	3.0e-37	148	COG1191	DNA-directed RNA polymerase specialized sigma subunit	247
643627905	704	47.53	11	694	15	695	0.0e+00	664	COG1298	Flagellar biosynthesis pathway, component FlhA	696
643627906	177	31.31	71	169	3	100	1.0e-09	56.2	COG3018	Uncharacterized protein	115
643627908	220	30.3	70	217	56	220	4.0e-16	78.5	COG1261	Flagella basal body P-ring formation protein FlgA	220
643627916	126	26.72	1	126	1	124	4.0e-11	60.3	COG1516	Flagellin-specific chaperone FliS	132
643627918	1095	19.71	478	1081	15	700	1.0e-23	106	COG0643	Chemotaxis protein histidine kinase CheA	716
643627920	567	31.74	194	502	76	408	4.0e-36	146	COG0840	Methyl-accepting chemotaxis protein	408
643627921	238	31.23	2	233	7	259	2.0e-37	149	COG1192	Cellulose biosynthesis protein BcsQ	259
643627922	170	37.97	15	170	8	165	4.0e-29	120	COG0835	Chemotaxis signal transduction protein	165
643627923	366	47.04	19	349	3	339	5.0e-81	294	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
643627924	269	37.11	6	257	1	253	7.0e-54	204	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
643627928	107	31.78	1	107	2	105	2.0e-12	64.6	COG1677	Flagellar hook-basal body complex protein FliE	105
643627929	561	30.34	11	556	4	545	2.0e-84	306	COG1766	Flagellar biosynthesis/type III secretory pathway M-ring protein FliF/YscJ	545
643627930	340	42.06	2	340	1	339	7.0e-77	280	COG1536	Flagellar motor switch protein FliG	339
643627932	442	47.74	1	441	2	440	0.0e+00	466	COG1157	Flagellar biosynthesis/type III secretory pathway ATPase	441
643627936	190	17.37	3	190	2	159	7.0e-10	57.2	COG1580	Flagellar basal body-associated protein FliL	159
643627937	323	28.04	7	323	4	322	4.0e-42	165	COG1868	Flagellar motor switch protein FliM	332
643627940	249	51.01	1	246	1	247	9.0e-68	250	COG1338	Flagellar biosynthetic protein FliP	248
643627941	89	41.38	2	88	1	87	2.0e-12	64	COG1987	Flagellar biosynthesis protein FliQ	89
643627942	269	35.34	15	263	8	255	1.0e-32	133	COG1684	Flagellar biosynthesis protein FliR	258
643627943	382	39.44	4	358	1	352	7.0e-80	290	COG1377	Flagellar biosynthesis protein FlhB	363
643627946	438	37.1	11	430	9	442	3.0e-105	375	COG1508	DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog	444
643627947	493	29.11	2	290	1	292	5.0e-27	115	COG1344	Flagellin and related hook-associated protein FlgL	360
643627948	551	22.77	24	408	22	416	1.0e-23	105	COG1345	Flagellar capping protein FliD	483
643627951	409	18.34	1	409	1	358	3.0e-20	93.2	COG1344	Flagellin and related hook-associated protein FlgL	360
643627952	1363	26.51	1	472	4	494	1.0e-40	162	COG1256	Flagellar hook-associated protein FlgK	552
643627954	371	48.93	1	371	4	365	2.0e-103	369	COG1706	Flagellar basal body P-ring protein FlgI	365
643627955	218	37.05	1	210	5	225	2.0e-37	149	COG2063	Flagellar basal body L-ring protein FlgH	230
643627956	262	52.85	4	262	3	264	2.0e-75	275	COG4786	Flagellar basal body rod protein FlgG	265
643627957	251	29.84	1	248	1	249	4.0e-31	128	COG4787	Flagellar basal body rod protein FlgF	251
643627958	423	33.49	1	422	3	422	1.0e-64	240	COG1749	Flagellar hook protein FlgE	423
643627959	223	32.44	1	222	5	221	2.0e-25	108	COG1843	Flagellar hook assembly protein FlgD	222
643627960	139	36.84	7	139	5	137	4.0e-26	110	COG1558	Flagellar basal body rod protein FlgC	137
643627961	128	37.8	8	128	8	133	3.0e-25	107	COG1815	Flagellar basal body rod protein FlgB	133
643627963	869	30.74	321	603	70	336	8.0e-32	132	COG0642	Signal transduction histidine kinase	336
643627964	175	37.93	30	174	17	155	2.0e-28	118	COG3915	Uncharacterized protein	155
643627965	210	40	8	210	1	209	4.0e-36	144	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
643627966	164	46.58	4	164	1	161	1.0e-41	162	COG3685	Ferritin-like metal-binding protein YciE	167
643627967	228	33.67	3	197	2	199	2.0e-34	139	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
643627968	317	38.61	4	316	4	317	3.0e-74	272	COG2390	DNA-binding transcriptional regulator LsrR, DeoR family	321
643627969	423	26	2	418	24	432	3.0e-40	159	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
643627970	310	34.71	20	307	2	290	8.0e-51	194	COG1175	ABC-type sugar transport system, permease component	295
643627971	276	36.43	1	276	2	281	4.0e-50	191	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
643627972	332	55.72	1	328	1	338	4.0e-128	451	COG3839	ABC-type sugar transport system, ATPase component	338
643627973	256	37.93	1	252	1	249	2.0e-38	152	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
643627974	477	43.93	3	474	2	473	0.0e+00	464	COG0246	Mannitol-1-phosphate/altronate dehydrogenases	473
643627976	365	69.97	1	358	1	363	0.0e+00	552	COG4663	TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component	363
643627977	682	60.19	4	522	1	443	0.0e+00	503	COG4664	TRAP-type mannitol/chloroaromatic compound transport system, large permease component	447
643627978	204	58.79	1	182	1	182	1.0e-65	242	COG4665	TRAP-type mannitol/chloroaromatic compound transport system, small permease component	182
643627979	128	37.29	5	120	2	119	2.0e-15	74.8	COG0838	NADH:ubiquinone oxidoreductase subunit 3 (chain A)	123
643627980	205	53.48	8	193	8	193	8.0e-59	220	COG0377	NADH:ubiquinone oxidoreductase 20 kD subunit (chhain B) or related Fe-S oxidoreductase	194
643627981	580	27.72	4	182	3	175	3.0e-22	100	COG0852	NADH:ubiquinone oxidoreductase 27 kD subunit (chain C)	176
643627981	580	53.75	194	580	12	398	0.0e+00	536	COG0649	NADH:ubiquinone oxidoreductase 49 kD subunit (chain D)	398
643627982	157	36.6	3	155	5	155	2.0e-38	151	COG1905	NADH:ubiquinone oxidoreductase 24 kD subunit (chain E)	160
643627983	416	48.09	6	413	12	423	2.0e-126	446	COG1894	NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F)	424
643627984	860	30.71	1	734	2	693	3.0e-118	420	COG1034	NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)	693
643627986	318	50.16	2	314	10	328	6.0e-78	284	COG1005	NADH:ubiquinone oxidoreductase subunit 1 (chain H)	332
643627987	164	42.11	2	152	13	159	9.0e-36	142	COG1143	Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)	172
643627988	164	33.97	9	162	11	166	2.0e-12	65.3	COG0839	NADH:ubiquinone oxidoreductase subunit 6 (chain J)	166
643627989	102	38.04	10	101	8	99	4.0e-11	59.7	COG0713	NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K)	100
643627990	700	34.61	8	575	1	555	6.0e-82	299	COG1009	NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit	606
643627991	482	40.86	1	482	4	489	3.0e-99	355	COG1008	NADH:ubiquinone oxidoreductase subunit 4 (chain M)	497
643627992	447	37.58	1	447	2	472	8.0e-51	195	COG1007	NADH:ubiquinone oxidoreductase subunit 2 (chain N)	475
643627993	483	20.96	14	403	53	409	1.0e-28	121	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
643627995	414	42.86	310	414	13	105	6.0e-13	68.9	COG2863	Cytochrome c553	121
643627997	857	24.38	680	838	33	192	1.0e-06	49.1	COG1845	Heme/copper-type cytochrome/quinol oxidase, subunit 3	209
643627997	857	44.74	49	537	8	501	4.0e-125	442	COG0843	Heme/copper-type cytochrome/quinol oxidase, subunit 1	566
643627998	324	28.14	10	232	3	229	6.0e-35	141	COG1622	Heme/copper-type cytochrome/quinol oxidase, subunit 2	247
643627999	243	28.88	37	221	32	217	4.0e-08	52.1	COG0671	Membrane-associated phospholipid phosphatase	232
643628002	233	46.15	166	230	1	65	8.0e-12	64.2	COG2771	DNA-binding transcriptional regulator, CsgD family	65
643628003	210	37.25	1	204	1	201	7.0e-44	170	COG3916	N-acyl-L-homoserine lactone synthetase	209
643628006	509	46.14	22	507	38	527	0.0e+00	484	COG3131	Periplasmic glucans biosynthesis protein	534
643628008	595	38.97	7	577	57	641	1.0e-126	447	COG2943	Membrane glycosyltransferase	736
643628009	399	42.71	2	380	14	387	4.0e-71	262	COG4645	Uncharacterized protein	410
643628011	353	53.94	11	351	2	339	3.0e-118	418	COG1135	ABC-type methionine transport system, ATPase component	339
643628012	206	62.81	1	199	24	222	7.0e-67	246	COG2011	ABC-type methionine transport system, permease component	222
643628013	258	55.43	1	258	2	268	8.0e-95	340	COG1464	ABC-type metal ion transport system, periplasmic component/surface antigen	268
643628015	496	31.99	6	477	15	478	5.0e-76	278	COG1757	Na+/H+ antiporter NhaC	485
643628021	302	34.52	45	296	5	232	5.0e-18	85.4	COG2801	Transposase InsO and inactivated derivatives	232
643628025	282	34.92	25	276	5	232	9.0e-18	84.3	COG2801	Transposase InsO and inactivated derivatives	232
643628033	553	39.38	105	263	2	157	3.0e-26	114	COG3436	Transposase	157
643628036	233	29.6	3	211	7	223	2.0e-24	105	COG0338	Site-specific DNA-adenine methylase	274
643628042	135	44.95	4	112	3	111	4.0e-27	113	COG0360	Ribosomal protein S6	112
643628043	75	68.66	4	70	9	75	3.0e-20	90.3	COG0238	Ribosomal protein S18	75
643628044	189	46.94	1	147	1	147	4.0e-41	161	COG0359	Ribosomal protein L9	148
643628045	444	38.34	1	439	1	441	1.0e-81	297	COG0544	FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)	441
643628048	277	41.54	11	275	18	284	2.0e-46	179	COG0063	NAD(P)H-hydrate repair enzyme Nnr, NAD(P)H-hydrate dehydratase domain	284
643628049	217	34.3	1	203	10	195	2.0e-28	118	COG0062	NAD(P)H-hydrate repair enzyme Nnr, NAD(P)H-hydrate epimerase domain	203
643628050	112	76.79	1	112	1	112	1.0e-39	154	COG0347	Nitrogen regulatory protein PII	112
643628051	459	45.16	2	459	11	443	0.0e+00	485	COG0174	Glutamine synthetase	443
643628052	350	35.24	136	342	6	213	4.0e-37	148	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
643628055	372	23.33	34	281	47	306	5.0e-13	69	COG0714	MoxR-like ATPase	329
643628056	436	17.07	41	436	46	389	1.0e-11	64.7	COG3864	Predicted metal-dependent peptidase	396
643628058	280	45.07	1	275	11	286	3.0e-62	232	COG2084	3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase	286
643628059	343	30.08	1	255	4	255	7.0e-34	138	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
643628060	379	43.81	1	377	1	387	7.0e-81	294	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
643628062	299	40.08	37	292	84	345	4.0e-61	228	COG4124	Beta-mannanase	355
643628063	627	22.47	60	484	3	439	3.0e-41	163	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
643628064	330	49.23	4	323	2	324	9.0e-130	456	COG1087	UDP-glucose 4-epimerase	329
643628065	311	36.75	2	294	13	308	2.0e-47	182	COG0451	Nucleoside-diphosphate-sugar epimerase	314
643628066	358	27.4	4	355	15	362	1.0e-45	177	COG0687	Spermidine/putrescine-binding periplasmic protein	363
643628068	557	33.58	13	552	1	530	7.0e-72	265	COG1178	ABC-type Fe3+ transport system, permease component	540
643628070	84	47.44	6	83	7	84	5.0e-15	72.6	COG3750	Uncharacterized conserved protein, UPF0335 family	85
643628073	105	33.33	8	104	10	108	7.0e-11	58.9	COG1734	RNA polymerase-binding transcription factor DksA	120
643628074	143	42.31	1	129	1	130	5.0e-29	120	COG3453	Predicted phosphohydrolase, protein tyrosine phosphatase (PTP) superfamily, DUF442 family	130
643628076	894	22.68	1	522	3	490	5.0e-44	173	COG0591	Na+/proline symporter	493
643628076	894	37.29	603	894	48	335	6.0e-39	156	COG0642	Signal transduction histidine kinase	336
643628080	281	46.79	23	279	7	264	9.0e-76	276	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
643628081	246	34.63	4	226	3	227	8.0e-35	140	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
643628082	313	37.3	6	313	5	322	2.0e-71	262	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
643628083	593	42.98	1	575	1	570	0.0e+00	610	COG0129	Dihydroxyacid dehydratase/phosphogluconate dehydratase	575
643628084	460	40.78	14	460	1	457	1.0e-82	300	COG0277	FAD/FMN-containing dehydrogenase	459
643628085	326	26.17	1	292	9	298	7.0e-36	144	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
643628086	283	34.65	29	280	7	258	8.0e-43	167	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
643628087	287	27.88	19	287	1	258	3.0e-35	142	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
643628088	267	47.64	10	263	1	245	2.0e-81	295	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
643628089	483	35.49	1	444	1	430	7.0e-114	404	COG0044	Dihydroorotase or related cyclic amidohydrolase	430
643628090	419	26.18	16	416	3	408	4.0e-48	186	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
643628091	210	27.33	8	166	4	162	9.0e-11	60.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
643628092	203	29.41	1	202	1	198	2.0e-12	65.8	COG1309	DNA-binding transcriptional regulator, AcrR family	201
643628093	434	33.95	4	325	2	310	2.0e-80	292	COG0167	Dihydroorotate dehydrogenase	310
643628094	179	25.61	11	172	8	171	3.0e-19	88.4	COG0586	Uncharacterized membrane protein DedA, SNARE-associated domain	208
643628095	443	36.2	18	440	2	450	1.0e-91	330	COG0493	NADPH-dependent glutamate synthase beta chain or related oxidoreductase	457
643628096	164	44.08	13	164	1	139	3.0e-21	95.1	COG0511	Biotin carboxyl carrier protein	140
643628097	448	64.13	1	444	1	446	0.0e+00	604	COG0439	Biotin carboxylase	449
643628098	214	54.26	4	187	21	206	5.0e-63	234	COG2360	Leu/Phe-tRNA-protein transferase	221
643628100	124	49.19	8	124	1	118	6.0e-22	96.3	COG3761	NADH:ubiquinone oxidoreductase 17.2 kD subunit	118
643628101	421	75.25	16	416	1	404	0.0e+00	706	COG1219	ATP-dependent protease Clp, ATPase subunit	408
643628102	210	68.91	11	203	2	194	1.0e-80	292	COG0740	ATP-dependent protease ClpP, protease subunit	200
643628103	202	23.44	14	202	1	190	2.0e-07	49.2	COG0558	Phosphatidylglycerophosphate synthase	192
643628104	401	45.48	4	400	2	383	2.0e-87	316	COG4134	ABC-type uncharacterized transport system YnjBCD, periplasmic component	384
643628105	562	38.8	17	560	10	550	7.0e-93	335	COG4135	ABC-type uncharacterized transport system YnjBCD, permease component	551
643628106	214	50.98	4	206	3	205	1.0e-58	219	COG4136	ABC-type uncharacterized transport system YnjBCD, ATPase component	213
643628107	156	33.33	1	155	46	207	2.0e-20	91.8	COG2340	Uncharacterized conserved protein YkwD, contains CAP (CSP/antigen 5/PR1) domain	207
643628108	439	29.69	161	437	41	327	6.0e-28	118	COG0642	Signal transduction histidine kinase	336
643628109	277	31.03	9	205	30	231	6.0e-18	84.9	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
643628116	336	39.53	1	334	11	352	9.0e-72	264	COG3424	Predicted naringenin-chalcone synthase	356
643628117	167	37.5	6	159	6	165	1.0e-27	116	COG1755	Uncharacterized protein YpbQ, isoprenylcysteine carboxyl methyltransferase (ICMT) family	172
643628122	253	36.36	1	249	1	253	4.0e-49	188	COG1291	Flagellar motor component MotA	266
643628125	329	46.83	1	329	3	322	4.0e-102	364	COG2896	Molybdenum cofactor biosynthesis enzyme MoaA	322
643628127	448	32.35	18	440	1	385	7.0e-48	185	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
643628128	387	28	9	387	17	408	3.0e-53	202	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
643628129	428	38.86	6	426	9	417	1.0e-72	267	COG4949	Uncharacterized membrane-anchored protein	424
643628131	482	51.22	1	481	1	463	0.0e+00	559	COG1282	NAD/NADP transhydrogenase beta subunit	463
643628132	523	52.99	2	369	1	356	9.0e-115	407	COG3288	NAD/NADP transhydrogenase alpha subunit	356
643628133	147	26.71	4	147	37	182	4.0e-13	67.4	COG2020	Protein-S-isoprenylcysteine O-methyltransferase Ste14	187
643628134	396	54.81	6	384	21	405	6.0e-122	430	COG3844	Kynureninase	407
643628135	342	41.1	7	217	11	228	5.0e-33	135	COG1376	Lipoprotein-anchoring transpeptidase ErfK/SrfK	232
643628136	252	39.39	13	243	21	243	6.0e-54	204	COG2071	Gamma-glutamyl-gamma-aminobutyrate hydrolase PuuD (putrescine degradation), contains GATase1-like domain	243
643628138	400	34.53	8	394	6	378	2.0e-69	256	COG0075	Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism protein PucG	383
643628139	590	38.35	14	582	2	565	2.0e-116	413	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
643628140	255	32.23	7	254	20	290	1.0e-38	153	COG0354	Folate-binding Fe-S cluster repair protein YgfZ, possible role in tRNA modification	305
643628141	163	42.99	1	107	25	131	1.0e-26	112	COG0231	Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)	131
643628144	458	29.3	5	419	21	450	1.0e-32	134	COG1538	Outer membrane protein TolC	457
643628145	217	34.13	7	213	1	208	7.0e-42	163	COG2518	Protein-L-isoaspartate O-methyltransferase	209
643628146	460	24.5	30	418	1	385	3.0e-33	136	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
643628147	648	57.58	10	633	2	624	0.0e+00	854	COG1154	Deoxyxylulose-5-phosphate synthase	627
643628155	491	20.48	14	401	39	439	4.0e-13	69.7	COG2710	Nitrogenase molybdenum-iron protein, alpha and beta chains	456
643628157	338	40.6	43	301	4	267	1.0e-57	217	COG1348	Nitrogenase subunit NifH, an ATPase	278
643628158	318	27.14	5	314	4	350	4.0e-29	122	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
643628160	278	33.68	3	269	16	294	2.0e-39	156	COG0142	Geranylgeranyl pyrophosphate synthase	322
643628161	481	27.42	1	480	13	487	1.0e-49	191	COG1233	Phytoene dehydrogenase-related protein	487
643628163	159	31.17	6	155	11	161	3.0e-20	91.5	COG3476	Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)	161
643628164	355	32.3	1	289	4	286	1.0e-35	144	COG1562	Phytoene/squalene synthetase	288
643628165	518	33.27	13	499	6	479	3.0e-71	263	COG1233	Phytoene dehydrogenase-related protein	487
643628167	334	52.31	1	317	10	333	8.0e-92	330	COG1239	Mg-chelatase subunit ChlI	423
643628168	558	33.33	290	548	6	252	6.0e-30	126	COG1240	Mg-chelatase subunit ChlD	261
643628169	288	30.5	16	284	2	281	3.0e-19	89.4	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
643628170	177	35.85	17	169	20	176	2.0e-25	108	COG1443	Isopentenyldiphosphate isomerase	185
643628171	394	32.19	1	364	2	370	7.0e-42	165	COG0644	Dehydrogenase (flavoprotein)	396
643628173	291	24.82	5	284	14	286	6.0e-20	91.9	COG0382	4-hydroxybenzoate polyprenyltransferase	289
643628175	612	24.95	22	474	30	482	8.0e-40	158	COG1032	Radical SAM superfamily enzyme YgiQ, UPF0313 family	490
643628179	428	21.82	41	428	47	451	1.0e-14	74.7	COG2710	Nitrogenase molybdenum-iron protein, alpha and beta chains	456
643628180	536	24.44	12	400	36	430	6.0e-28	119	COG2710	Nitrogenase molybdenum-iron protein, alpha and beta chains	456
643628181	1193	31.88	169	1189	122	1250	0.0e+00	667	COG1429	Cobalamin biosynthesis protein CobN, Mg-chelatase	1388
643628182	297	40.74	32	294	2	267	1.0e-72	266	COG1348	Nitrogenase subunit NifH, an ATPase	278
643628183	228	25.79	5	185	3	185	3.0e-15	75.3	COG2227	2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase	243
643628191	145	38.03	5	145	10	134	7.0e-21	93.1	COG3474	Cytochrome c2	135
643628192	232	50.88	1	224	2	227	8.0e-79	286	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
643628193	247	58.94	1	246	2	246	1.0e-90	326	COG4674	ABC-type uncharacterized transport system, ATPase component	249
643628194	410	31.51	16	379	1	307	3.0e-38	152	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
643628195	642	37.58	345	640	3	297	7.0e-59	222	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
643628196	426	30.38	18	383	1	365	7.0e-66	245	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
643628197	207	47.21	6	201	14	202	3.0e-56	211	COG0378	Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase	202
643628198	210	41.7	3	208	5	227	1.0e-36	146	COG0830	Urease accessory protein UreF	229
643628199	182	42.55	24	160	24	155	7.0e-23	100	COG2371	Urease accessory protein UreE	155
643628201	568	75.7	2	568	1	568	0.0e+00	1014	COG0804	Urease alpha subunit	568
643628205	101	65.35	1	101	1	101	7.0e-41	158	COG0832	Urease beta subunit	106
643628206	100	70	1	100	1	100	1.0e-41	161	COG0831	Urease gamma subunit	100
643628207	275	35.47	13	273	5	269	8.0e-44	170	COG0829	Urease accessory protein UreH	269
643628208	345	28.14	9	338	2	325	1.0e-44	173	COG2334	Ser/Thr protein kinase RdoA involved in Cpx stress response, MazF antagonist	331
643628209	436	39.2	5	435	2	446	2.0e-109	389	COG0160	4-aminobutyrate aminotransferase or related aminotransferase	447
643628213	214	34	1	199	4	200	2.0e-27	116	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
643628214	452	33.49	18	442	7	413	4.0e-95	342	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
643628215	231	27.19	5	229	2	216	9.0e-18	83.9	COG4094	Uncharacterized membrane protein	219
643628218	624	37.26	5	620	1	635	8.0e-99	355	COG4548	Nitric oxide reductase activation protein	637
643628224	233	29.86	8	218	1	211	2.0e-35	142	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
643628225	397	46.41	4	390	5	392	4.0e-64	239	COG3213	Uncharacterized protein involved in response to NO	396
643628226	336	28.98	7	169	2	175	8.0e-11	61.6	COG2203	GAF domain	175
643628226	336	41.34	142	319	1	179	3.0e-33	136	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
643628228	356	27.76	40	355	28	353	3.0e-38	152	COG3405	Endo-1,4-beta-D-glucanase Y	360
643628230	766	26.53	67	485	1	407	5.0e-48	186	COG1215	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase	439
643628233	789	44.98	516	764	1	244	8.0e-73	268	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
643628234	273	25.68	2	245	1	250	2.0e-19	89.6	COG1409	3',5'-cyclic AMP phosphodiesterase CpdA	301
643628235	305	27.57	5	299	4	297	2.0e-31	130	COG1597	Diacylglycerol kinase family enzyme	301
643628237	331	30.33	1	323	21	352	5.0e-26	111	COG0628	Predicted PurR-regulated permease PerM	355
643628238	425	30.07	1	421	7	421	9.0e-56	211	COG0402	Cytosine/adenosine deaminase or related metal-dependent hydrolase	421
643628239	315	40.84	4	314	1	304	6.0e-64	237	COG1079	ABC-type uncharacterized transport system, permease component	304
643628240	328	44.07	2	327	21	349	3.0e-63	235	COG4603	ABC-type uncharacterized transport system, permease component	356
643628241	506	51.6	4	499	2	501	0.0e+00	597	COG3845	ABC-type uncharacterized transport system, ATPase component	501
643628242	334	34.51	9	332	7	342	2.0e-53	203	COG1744	Basic membrane lipoprotein Med, periplasmic binding protein (PBP1-ABC) superfamily	345
643628243	366	29.34	54	364	1	299	2.0e-39	156	COG1840	ABC-type Fe3+ transport system, periplasmic component	299
643628244	281	69.04	1	281	2	282	2.0e-92	332	COG4132	ABC-type uncharacterized transport system, permease component	282
643628245	263	24.16	2	263	7	267	7.0e-35	141	COG1177	ABC-type spermidine/putrescine transport system, permease component II	267
643628246	352	48.44	1	352	3	352	3.0e-108	385	COG3842	ABC-type Fe3+/spermidine/putrescine transport systems, ATPase components	352
643628248	339	27.38	1	327	1	304	2.0e-48	186	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
643628249	107	40.19	1	106	1	102	2.0e-16	77.8	COG0633	Ferredoxin	102
643628252	493	43.29	18	378	4	345	8.0e-70	258	COG0265	Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain	347
643628253	340	29.45	3	286	2	286	6.0e-32	131	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
643628254	393	27.4	84	370	5	286	1.0e-42	167	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
643628255	452	37.8	1	446	1	454	2.0e-112	399	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
643628256	262	50.85	6	237	1	226	4.0e-66	244	COG0120	Ribose 5-phosphate isomerase	227
643628258	491	47.16	206	487	1	262	2.0e-78	286	COG1760	L-serine deaminase	262
643628259	307	21.32	36	294	32	293	1.0e-05	44	COG2962	Uncharacterized membrane protein RarD, contains two EamA domains	293
643628262	430	59.53	1	429	1	430	0.0e+00	635	COG0104	Adenylosuccinate synthase	430
643628264	227	35.96	1	85	1	86	5.0e-17	81.4	COG1314	Preprotein translocase subunit SecG	86
643628265	547	57.72	3	545	2	531	0.0e+00	825	COG0504	CTP synthase (UTP-ammonia lyase)	533
643628266	260	43.25	2	248	1	252	2.0e-59	222	COG2961	23S rRNA A2030 N6-methylase RlmJ	279
643628267	145	34.51	1	142	6	147	1.0e-16	79.2	COG4103	Uncharacterized conserved protein, tellurite resistance protein B (TerB) family	148
643628268	265	63.1	13	263	3	254	1.0e-100	359	COG4598	ABC-type histidine transport system, ATPase component	256
643628269	241	30.19	1	238	3	267	1.0e-30	126	COG0834	ABC-type amino acid transport/signal transduction system, periplasmic component/domain	275
643628270	293	29.48	33	283	14	230	1.0e-34	140	COG4215	ABC-type arginine transport system, permease component	230
643628271	275	34.8	35	259	12	226	6.0e-36	144	COG4160	ABC-type arginine/histidine transport system, permease component	228
643628272	445	36.84	2	444	6	443	6.0e-104	371	COG0174	Glutamine synthetase	443
643628273	225	32.07	20	192	11	194	6.0e-31	127	COG0518	GMP synthase - Glutamine amidotransferase domain	198
643628274	451	37.91	9	450	3	443	3.0e-110	392	COG0174	Glutamine synthetase	443
643628275	433	28.86	33	412	1	387	2.0e-47	183	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
643628276	455	38.69	18	454	14	448	4.0e-120	424	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
643628277	184	38.66	1	184	3	193	6.0e-30	123	COG5394	Polyhydroxyalkanoate (PHA) synthesis regulator protein, binds DNA and PHA	193
643628279	601	46.98	150	596	8	444	0.0e+00	484	COG3243	Poly(3-hydroxyalkanoate) synthetase	445
643628280	423	40.87	6	416	2	415	4.0e-100	358	COG4553	Poly-beta-hydroxyalkanoate depolymerase	415
643628281	250	23.74	6	223	1	217	8.0e-12	64.3	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
643628282	646	52.05	36	643	1	581	0.0e+00	716	COG0441	Threonyl-tRNA synthetase	589
643628283	83	63.24	16	83	1	67	2.0e-21	93.7	COG1278	Cold shock protein, CspA family	67
643628284	108	31.3	1	108	3	116	2.0e-16	77.5	COG1393	Arsenate reductase and related proteins, glutaredoxin family	117
643628285	134	37.21	1	129	1	128	8.0e-17	79.6	COG4852	Uncharacterized membrane protein	134
643628286	159	43.92	1	140	1	148	1.0e-33	135	COG0262	Dihydrofolate reductase	167
643628287	298	47.3	3	298	1	268	4.0e-87	314	COG0207	Thymidylate synthase	268
643628288	142	30.66	4	122	2	138	6.0e-12	63.3	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
643628289	362	39.55	145	362	2	217	1.0e-45	177	COG1985	Pyrimidine reductase, riboflavin biosynthesis	218
643628289	362	60.28	3	143	6	146	5.0e-48	185	COG0117	Pyrimidine deaminase domain of riboflavin biosynthesis protein RibD	146
643628290	155	52.9	1	155	1	155	1.0e-50	192	COG1327	Transcriptional regulator NrdR, contains Zn-ribbon and ATP-cone domains	156
643628292	668	58.45	386	667	60	342	6.0e-94	338	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
643628293	643	34.44	3	500	2	496	7.0e-99	355	COG0358	DNA primase (bacterial type)	568
643628295	475	36.86	5	475	1	410	2.0e-94	339	COG0334	Glutamate dehydrogenase/leucine dehydrogenase	411
643628299	178	23.13	1	131	7	139	3.0e-07	48.6	COG4961	Flp pilus assembly protein TadG	185
643628300	196	25.14	1	183	2	184	3.0e-06	45.4	COG1309	DNA-binding transcriptional regulator, AcrR family	201
643628302	410	45.71	2	308	19	333	8.0e-88	317	COG0460	Homoserine dehydrogenase	333
643628303	311	53.16	2	304	5	317	8.0e-105	373	COG1494	Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase or related protein	332
643628304	583	41.7	64	551	6	485	1.0e-95	344	COG0608	Single-stranded DNA-specific exonuclease, DHH superfamily, may be involved in archaeal DNA replication intiation	491
643628306	353	46.37	174	349	3	180	7.0e-34	138	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
643628307	331	43.15	1	329	1	323	4.0e-86	311	COG1052	Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase	324
643628310	285	27.06	33	237	26	238	6.0e-14	71.6	COG5607	CHAD domain (function unknown)	283
643628311	335	47.51	147	323	1	180	2.0e-36	146	COG2199	GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants	181
643628314	232	32.48	1	228	1	218	5.0e-28	117	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
643628316	461	36.71	17	458	3	435	3.0e-67	249	COG3706	Two-component response regulator, PleD family, consists of two REC domains and a diguanylate cyclase (GGDEF) domain	435
643628319	212	42.31	27	206	1	181	1.0e-22	99.8	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
643628321	131	40.98	4	125	4	125	1.0e-28	118	COG5349	Uncharacterized conserved protein, DUF983 family	126
643628326	346	36	1	346	1	315	1.0e-71	263	COG0667	Predicted oxidoreductase (related to aryl-alcohol dehydrogenase)	316
643628329	572	40.42	1	569	4	558	0.0e+00	559	COG0143	Methionyl-tRNA synthetase	558
643628330	832	31.42	1	428	2	414	1.0e-45	178	COG0025	NhaP-type Na+/H+ or K+/H+ antiporter	429
643628333	618	30.81	18	613	138	708	2.0e-78	287	COG2274	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	709
643628335	325	47.81	13	325	1	315	2.0e-75	276	COG1270	Cobalamin biosynthesis protein CobD/CbiB	320
643628336	406	53.48	1	399	2	400	0.0e+00	464	COG0520	Selenocysteine lyase/Cysteine desulfurase	405
643628339	428	28	30	422	21	410	4.0e-54	205	COG0719	Fe-S cluster assembly scaffold protein SufB	412
643628340	252	61.69	1	248	3	245	9.0e-100	356	COG0396	Fe-S cluster assembly ATPase SufC	251
643628341	103	58.1	1	102	1	105	3.0e-28	116	COG0393	Uncharacterized conserved protein YbjQ, UPF0145 family	108
643628342	509	43.7	52	507	1	412	2.0e-126	445	COG0719	Fe-S cluster assembly scaffold protein SufB	412
643628343	348	40.84	4	347	2	382	5.0e-85	308	COG1104	Cysteine sulfinate desulfinase/cysteine desulfurase or related enzyme	386
643628344	155	35.51	1	138	1	134	4.0e-26	110	COG1959	DNA-binding transcriptional regulator, IscR family	150
643628345	219	57.75	1	213	4	207	2.0e-72	264	COG2945	Alpha/beta superfamily hydrolase	210
643628346	194	32.64	7	146	4	146	9.0e-17	80	COG1896	5'-deoxynucleotidase YfbR and related HD superfamily hydrolases	193
643628347	404	32.3	1	399	14	407	4.0e-124	438	COG0538	Isocitrate dehydrogenase	407
643628349	606	59.5	1	605	3	603	0.0e+00	926	COG1217	Predicted membrane GTPase involved in stress response	603
643628350	264	31.91	1	248	1	244	8.0e-44	170	COG0121	Predicted glutamine amidotransferase	252
643628351	96	51.06	1	93	1	94	6.0e-21	92.3	COG5470	Uncharacterized conserved protein, DUF1330 family	96
643628352	883	54.32	1	881	5	875	0.0e+00	1131	COG0013	Alanyl-tRNA synthetase	879
643628353	367	65.14	24	304	4	279	4.0e-91	328	COG0468	RecA/RadA recombinase	279
643628356	387	30.65	95	387	34	355	1.0e-50	193	COG0144	16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family	355
643628357	259	41.9	1	253	1	253	2.0e-65	242	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
643628360	360	59.3	7	348	1	341	5.0e-128	451	COG2899	Uncharacterized protein	346
643628362	1063	27.09	14	1062	2	1007	0.0e+00	535	COG0841	Multidrug efflux pump subunit AcrB	1009
643628363	317	32.03	24	314	48	353	2.0e-12	67.1	COG0845	Multidrug efflux pump subunit AcrA (membrane-fusion protein)	372
643628364	295	34.59	1	291	8	297	5.0e-58	218	COG0053	Divalent metal cation (Fe/Co/Zn/Cd) transporter	304
643628365	298	24.59	3	295	2	302	9.0e-36	144	COG0826	Collagenase-like protease, PrtC family	347
643628366	326	37.5	1	326	7	312	1.0e-71	263	COG0826	Collagenase-like protease, PrtC family	347
643628367	174	26.51	4	168	5	165	8.0e-14	70.3	COG3154	Predicted lipid carrier protein YhbT, SCP2 domain	168
643628368	497	47.86	7	496	3	476	0.0e+00	539	COG0043	3-polyprenyl-4-hydroxybenzoate decarboxylase	477
643628369	184	50.27	1	184	3	187	2.0e-55	208	COG0163	3-polyprenyl-4-hydroxybenzoate decarboxylase	191
643628370	396	38.52	1	396	1	403	5.0e-96	344	COG0579	L-2-hydroxyglutarate oxidase LhgO	429
643628371	505	38.79	21	296	21	299	3.0e-59	223	COG2187	Aminoglycoside phosphotransferase family enzyme	337
643628371	505	41.38	330	503	1	170	5.0e-26	112	COG0645	Predicted kinase	170
643628373	240	41.8	1	234	5	259	4.0e-41	161	COG3568	Metal-dependent hydrolase, endonuclease/exonuclease/phosphatase family	259
643628374	516	32.71	57	479	48	423	9.0e-59	221	COG1502	Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase or related enzyme	438
643628375	140	34.29	1	140	13	147	2.0e-12	65.4	COG3909	Cytochrome c556	147
643628376	199	37.5	14	196	5	185	1.0e-29	123	COG3658	Cytochrome b	192
643628377	219	34.25	6	218	1	219	2.0e-41	162	COG0235	Ribulose-5-phosphate 4-epimerase/Fuculose-1-phosphate aldolase	219
643628378	223	46.98	8	218	4	218	4.0e-64	237	COG2846	Iron-sulfur cluster repair protein YtfE, RIC family, contains ScdAN and hemerythrin domains	221
643628380	328	50	2	326	16	318	7.0e-109	387	COG2269	Elongation factor P--beta-lysine ligase (EF-P beta-lysylation pathway)	322
643628381	188	36.92	1	130	2	131	2.0e-33	135	COG0231	Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)	131
643628382	464	51.08	11	461	17	473	0.0e+00	460	COG0246	Mannitol-1-phosphate/altronate dehydrogenases	473
643628383	241	41.57	4	239	1	251	6.0e-37	147	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
643628384	274	54.32	4	274	1	278	2.0e-113	401	COG3717	5-keto 4-deoxyuronate isomerase	278
643628386	426	53.81	46	426	1	379	1.0e-97	350	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
643628387	181	36.75	11	176	8	173	2.0e-26	111	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
643628388	321	43.34	1	321	8	330	5.0e-98	351	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
643628389	468	44.09	2	468	1	461	0.0e+00	573	COG1904	Glucuronate isomerase	463
643628390	240	32.17	5	231	2	230	5.0e-32	131	COG1802	DNA-binding transcriptional regulator, GntR family	230
643628391	297	34.74	4	295	1	294	1.0e-33	137	COG0524	Sugar or nucleoside kinase, ribokinase family	311
643628393	330	27.44	1	320	49	352	1.0e-53	203	COG1740	Ni,Fe-hydrogenase I small subunit	355
643628394	475	29.95	1	475	1	530	3.0e-87	316	COG0374	Ni,Fe-hydrogenase I large subunit	545
643628395	758	45.57	8	750	2	748	0.0e+00	714	COG0068	Hydrogenase maturation factor HypF (carbamoyltransferase)	750
643628396	369	57.51	5	356	2	354	0.0e+00	513	COG1740	Ni,Fe-hydrogenase I small subunit	355
643628397	596	56.16	14	596	1	545	0.0e+00	693	COG0374	Ni,Fe-hydrogenase I large subunit	545
643628398	191	43.08	1	191	9	199	2.0e-15	75.7	COG2370	Hydrogenase/urease accessory protein HupE	201
643628399	261	47.03	41	256	10	227	4.0e-53	201	COG1969	Ni,Fe-hydrogenase I cytochrome b subunit	227
643628400	198	37.18	2	157	5	160	7.0e-30	123	COG0680	Ni,Fe-hydrogenase maturation factor	160
643628404	252	44.23	18	69	1	52	7.0e-12	64.5	COG1773	Rubredoxin	55
643628406	113	46.02	1	113	1	113	5.0e-25	106	COG0375	Zn finger protein HypA/HybF (possibly regulating hydrogenase expression)	115
643628408	230	42.36	20	217	1	196	4.0e-54	204	COG0378	Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase	202
643628409	491	34.43	1	483	2	462	1.0e-90	327	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
643628410	96	52.5	1	80	1	76	6.0e-17	79.2	COG0298	Hydrogenase maturation factor	82
643628411	379	50.53	1	374	1	364	6.0e-130	457	COG0409	Hydrogenase maturation factor	364
643628412	340	49.13	6	340	1	339	6.0e-89	321	COG0309	Hydrogenase maturation factor	339
643628413	131	26.42	23	128	6	109	1.0e-09	55.3	COG0607	Rhodanese-related sulfurtransferase	110
643628414	191	28.57	10	191	1	209	3.0e-22	98.5	COG2197	DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains	211
643628415	941	27.6	408	771	10	356	6.0e-29	123	COG3852	Signal transduction histidine kinase, nitrogen specific	363
643628417	337	37.19	10	320	3	314	7.0e-52	197	COG0451	Nucleoside-diphosphate-sugar epimerase	314
643628418	358	31.69	5	357	1	366	7.0e-70	257	COG4641	Spore maturation protein CgeB	373
643628419	363	32.35	4	363	1	373	1.0e-78	286	COG4641	Spore maturation protein CgeB	373
643628420	369	29.38	4	367	2	370	6.0e-72	264	COG4641	Spore maturation protein CgeB	373
643628421	366	23.61	4	356	3	378	1.0e-22	100	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
643628422	672	30.79	320	654	4	312	8.0e-46	179	COG0451	Nucleoside-diphosphate-sugar epimerase	314
643628423	352	28.24	1	328	16	320	1.0e-36	147	COG1087	UDP-glucose 4-epimerase	329
643628424	332	27.97	18	330	1	349	8.0e-44	170	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
643628425	341	28.1	12	333	5	331	8.0e-38	151	COG0673	Predicted dehydrogenase	342
643628426	262	50.97	1	259	1	257	2.0e-84	305	COG1273	Non-homologous end joining protein Ku, dsDNA break repair	278
643628427	249	47.79	2	248	21	267	1.0e-74	273	COG1273	Non-homologous end joining protein Ku, dsDNA break repair	278
643628429	219	36.82	1	214	6	224	2.0e-34	138	COG1272	Predicted membrane channel-forming protein YqfA, hemolysin III family	226
643628430	143	53.15	1	143	1	142	1.0e-37	148	COG5579	Uncharacterized protein, DUF1810 family	143
643628431	434	34.99	1	430	1	443	4.0e-96	345	COG1508	DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog	444
643628433	392	41.87	20	384	3	375	2.0e-79	289	COG0119	Isopropylmalate/homocitrate/citramalate synthases	409
643628434	388	51.69	4	382	2	384	4.0e-129	455	COG1104	Cysteine sulfinate desulfinase/cysteine desulfurase or related enzyme	386
643628435	246	33.78	165	235	12	85	9.0e-08	51.1	COG0694	Fe-S cluster biogenesis protein NfuA, 4Fe-4S-binding domain	93
643628435	246	37.78	7	122	10	144	6.0e-14	71.5	COG0822	NifU homolog involved in Fe-S cluster formation	150
643628436	106	46.67	1	105	4	108	3.0e-31	126	COG0316	Fe-S cluster assembly iron-binding protein IscA	110
643628441	457	29.41	12	437	26	446	5.0e-58	218	COG2710	Nitrogenase molybdenum-iron protein, alpha and beta chains	456
643628442	487	32.69	3	461	2	450	1.0e-86	313	COG2710	Nitrogenase molybdenum-iron protein, alpha and beta chains	456
643628443	508	35.01	54	501	17	444	2.0e-94	339	COG2710	Nitrogenase molybdenum-iron protein, alpha and beta chains	456
643628444	493	37.68	25	491	1	449	1.0e-100	360	COG2710	Nitrogenase molybdenum-iron protein, alpha and beta chains	456
643628445	293	71.94	6	282	1	277	5.0e-122	430	COG1348	Nitrogenase subunit NifH, an ATPase	278
643628447	71	44.12	1	68	1	68	1.0e-11	61.6	COG5554	Nitrogen fixation protein	69
643628451	491	26.73	373	470	1	99	6.0e-07	49.5	COG1433	Predicted Fe-Mo cluster-binding protein, NifX family	121
643628453	582	35.88	24	582	35	550	4.0e-125	442	COG3604	Transcriptional regulator containing GAF, AAA-type ATPase, and DNA-binding Fis domains	550
643628454	131	34.23	15	124	3	107	1.0e-12	65.3	COG0607	Rhodanese-related sulfurtransferase	110
643628456	389	37.5	5	371	16	377	2.0e-84	306	COG1686	D-alanyl-D-alanine carboxypeptidase	389
643628457	217	47.85	4	212	2	205	2.0e-54	205	COG0125	Thymidylate kinase	208
643628459	113	53.4	7	109	4	106	2.0e-20	90.9	COG2076	Multidrug transporter EmrE and related cation transporters	106
643628460	341	63.64	5	332	2	331	0.0e+00	495	COG2255	Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit	332
643628461	291	36.92	2	272	37	298	8.0e-39	154	COG0501	Zn-dependent protease with chaperone function	302
643628462	224	40.91	1	220	1	200	7.0e-49	186	COG0632	Holliday junction resolvasome RuvABC DNA-binding subunit	201
643628463	168	52.87	4	159	1	157	2.0e-44	171	COG0817	Holliday junction resolvasome RuvABC endonuclease subunit	160
643628465	291	34.42	1	291	1	300	5.0e-54	204	COG2264	Ribosomal protein L11 methylase PrmA	300
643628466	224	60.12	41	213	1	170	7.0e-71	260	COG0225	Peptide methionine sulfoxide reductase MsrA	174
643628467	720	46.56	8	719	11	730	0.0e+00	700	COG1198	Primosomal protein N' (replication factor Y) - superfamily II helicase	730
643628468	219	48.71	1	218	8	239	4.0e-67	247	COG0176	Transaldolase	239
643628469	229	21.24	4	229	7	218	4.0e-11	61.8	COG3159	Uncharacterized conserved protein YigA, DUF484 family	218
643628470	306	36.6	7	306	3	300	8.0e-61	227	COG4974	Site-specific recombinase XerD	300
643628472	238	24.44	6	227	2	222	6.0e-27	114	COG1183	Phosphatidylserine synthase	234
643628474	147	37.04	7	144	9	168	9.0e-24	102	COG0350	O6-methylguanine-DNA--protein-cysteine methyltransferase	168
643628476	999	42.61	9	998	1	929	0.0e+00	1049	COG0060	Isoleucyl-tRNA synthetase	933
643628477	351	32.95	6	351	1	341	5.0e-49	188	COG3768	Uncharacterized membrane protein YcjF, UPF0283 family	350
643628478	462	40.88	1	462	1	466	6.0e-118	418	COG3106	Predicted ATPase, YcjX-like family	467
643628480	255	42.46	1	252	1	247	1.0e-77	282	COG0101	tRNA U38,U39,U40 pseudouridine synthase TruA	266
643628484	611	34.15	14	610	7	610	2.0e-126	446	COG2905	Signal-transduction protein containing cAMP-binding, CBS, and nucleotidyltransferase domains	610
643628486	93	47.62	10	93	5	87	4.0e-19	86.2	COG4327	Uncharacterized membrane protein	101
643628487	229	38.21	14	225	3	178	5.0e-42	164	COG0563	Adenylate kinase or related kinase	178
643628488	653	44.88	71	626	1	523	0.0e+00	653	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
643628490	545	45.11	20	526	12	529	3.0e-106	379	COG0659	Sulfate permease or related transporter, MFS superfamily	554
643628492	507	30.54	57	463	17	441	5.0e-42	165	COG2027	D-alanyl-D-alanine carboxypeptidase	470
643628494	526	37.36	11	520	1	521	0.0e+00	529	COG1384	Lysyl-tRNA synthetase, class I	521
643628495	140	36.11	3	140	2	143	6.0e-23	100	COG1764	Organic hydroperoxide reductase OsmC/OhrA	143
643628496	192	32.98	1	184	3	170	3.0e-35	141	COG1057	Nicotinic acid mononucleotide adenylyltransferase	197
643628497	551	47.86	5	533	1	530	0.0e+00	571	COG0488	ATPase components of ABC transporters with duplicated ATPase domains	530
643628502	68	63.24	1	68	1	67	2.0e-20	90.6	COG1278	Cold shock protein, CspA family	67
643628503	317	37.71	30	308	18	312	2.0e-36	146	COG0657	Acetyl esterase/lipase	312
643628504	501	32.5	3	446	4	471	2.0e-74	273	COG3119	Arylsulfatase A or related enzyme	475
643628505	168	35.48	22	168	18	171	2.0e-24	105	COG3040	Bacterial lipocalin	174
643628506	668	43.22	1	665	7	682	0.0e+00	734	COG0339	Zn-dependent oligopeptidase	683
643628507	349	56.45	100	343	6	253	3.0e-75	275	COG0476	Molybdopterin or thiamine biosynthesis adenylyltransferase	254
643628508	155	59.57	14	154	13	147	3.0e-47	181	COG0756	dUTPase	148
643628509	396	49.24	1	394	1	390	5.0e-109	388	COG0452	Phosphopantothenoylcysteine synthetase/decarboxylase	392
643628510	275	21.49	22	237	47	262	9.0e-16	77.7	COG3016	Uncharacterized iron-regulated protein	295
643628511	292	36.97	9	288	70	339	2.0e-52	199	COG0568	DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)	342
643628512	184	51.72	12	177	2	175	3.0e-51	194	COG2087	Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase	175
643628513	192	33	1	190	2	199	5.0e-23	101	COG0406	Broad specificity phosphatase PhoE	208
643628515	363	25	116	348	62	298	6.0e-07	48.7	COG4974	Site-specific recombinase XerD	300
643628517	131	46.91	50	130	4	84	9.0e-16	75.7	COG3750	Uncharacterized conserved protein, UPF0335 family	85
643628530	291	29.12	1	281	1	267	3.0e-38	152	COG3649	CRISPR/Cas system type I-B associated protein Csh2, Cas7 group, RAMP superfamily	283
643628531	201	24.18	2	179	22	188	2.0e-15	75.8	COG1468	CRISPR/Cas system-associated exonuclease Cas4, RecB family	190
643628532	344	33.43	4	343	2	327	2.0e-65	242	COG1518	CRISPR/Cas system-associated endonuclease Cas1	327
643628533	96	40.66	1	91	1	87	2.0e-18	84.1	COG1343	CRISPR/Cas system-associated endoribonuclease Cas2	89
643628535	286	32.9	6	155	17	171	1.0e-19	90.5	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
643628536	257	35.42	2	191	12	202	1.0e-34	140	COG0300	Short-chain dehydrogenase	265
643628537	115	49.48	19	115	13	108	6.0e-23	99.3	COG1733	DNA-binding transcriptional regulator, HxlR family	120
643628538	202	39.9	2	196	9	205	6.0e-25	107	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
643628540	305	39.14	1	304	1	326	4.0e-55	208	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
643628541	247	32.2	127	243	1	118	3.0e-14	72.6	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
643628543	289	26.37	26	288	17	282	2.0e-14	73.2	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
643628544	128	58.14	1	128	2	130	2.0e-45	174	COG5485	Predicted ester cyclase	131
643628548	60	38.6	3	55	10	64	3.0e-08	50.1	COG3024	Endogenous inhibitor of DNA gyrase, YacG/DUF329 family	65
643628549	346	28.27	18	346	16	395	1.0e-37	150	COG1530	Ribonuclease G or E	487
643628550	192	50.53	1	187	3	191	5.0e-55	207	COG0424	Predicted house-cleaning NTP pyrophosphatase, Maf/HAM1 superfamily	193
643628551	72	65.28	1	72	1	72	7.0e-22	95.6	COG0361	Translation initiation factor IF-1	75
643628552	291	33.69	1	275	3	262	5.0e-32	131	COG0388	Predicted amidohydrolase	274
643628554	133	25.78	1	123	4	122	1.0e-06	45.7	COG3631	Ketosteroid isomerase-related protein	133
643628555	163	29.45	7	148	1	139	8.0e-26	109	COG0394	Protein-tyrosine-phosphatase	139
643628556	158	57.42	3	157	10	158	4.0e-49	187	COG5328	Uncharacterized protein, UPF0262 family	160
643628557	434	55.24	13	432	8	425	0.0e+00	526	COG0141	Histidinol dehydrogenase	425
643628559	422	63.03	1	422	1	420	0.0e+00	585	COG0766	UDP-N-acetylglucosamine enolpyruvyl transferase	421
643628562	435	31.28	62	434	10	378	3.0e-53	203	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
643628563	172	23.9	1	159	4	158	6.0e-09	53.8	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
643628564	374	21.68	1	301	1	301	2.0e-29	123	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
643628565	241	27.59	122	237	2	114	6.0e-09	54.9	COG3450	Predicted enzyme of the cupin superfamily	116
643628566	430	29.19	29	409	1	385	5.0e-43	168	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
643628567	558	40.76	3	549	2	548	1.0e-125	443	COG0146	N-methylhydantoinase B/oxoprolinase/acetone carboxylase, alpha subunit	563
643628568	680	39	7	679	1	674	0.0e+00	494	COG0145	N-methylhydantoinase A/oxoprolinase/acetone carboxylase, beta subunit	674
643628570	314	32.31	15	306	8	292	8.0e-08	51.4	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
643628572	517	25.7	4	285	26	307	2.0e-22	100	COG3447	Integral membrane sensor domain MASE1	308
643628572	517	33.94	303	517	2	219	9.0e-37	148	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
643628573	238	42.86	1	236	13	250	3.0e-38	151	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
643628574	226	41.23	8	224	10	237	8.0e-44	170	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
643628575	311	32.68	4	299	15	316	1.0e-33	137	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
643628576	267	51.7	1	264	2	263	2.0e-80	292	COG0351	Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase	263
643628577	203	46.46	3	196	6	202	2.0e-38	151	COG0352	Thiamine monophosphate synthase	211
643628578	262	49.81	6	260	5	263	3.0e-71	262	COG2145	Hydroxyethylthiazole kinase, sugar kinase family	265
643628580	264	38.61	6	257	2	260	2.0e-57	216	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
643628581	328	49.38	3	322	1	322	2.0e-126	445	COG1087	UDP-glucose 4-epimerase	329
643628582	434	53.35	1	418	1	413	0.0e+00	545	COG1004	UDP-glucose 6-dehydrogenase	414
643628584	248	62.66	1	240	1	241	2.0e-97	348	COG0217	Transcriptional and/or translational regulatory protein YebC/TACO1	241
643628585	593	20.56	62	593	2	458	1.0e-30	128	COG0471	Di- and tricarboxylate transporter	461
643628586	252	52.38	1	252	18	266	2.0e-90	325	COG1692	Calcineurin-like phosphoesterase	266
643628587	799	32.93	4	794	8	799	0.0e+00	629	COG1201	Lhr-like helicase	814
643628588	228	36.13	9	184	3	192	2.0e-29	122	COG1407	Metallophosphoesterase superfamily enzyme	235
643628589	296	57.75	6	289	3	283	7.0e-107	380	COG0190	5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase	283
643628590	105	34.02	1	96	1	97	1.0e-11	61.5	COG1605	Chorismate mutase	101
643628591	557	66.06	5	557	1	554	0.0e+00	872	COG2759	Formyltetrahydrofolate synthetase	554
643628593	623	56.38	2	589	5	595	0.0e+00	706	COG0465	ATP-dependent Zn proteases	596
643628594	412	33.86	5	250	11	261	5.0e-39	155	COG0037	tRNA(Ile)-lysidine synthase TilS/MesJ	298
643628595	274	26.42	1	265	1	255	1.0e-22	100	COG1729	Periplasmic TolA-binding protein (function unknown)	262
643628596	182	33.88	1	177	6	188	5.0e-31	127	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
643628597	435	36.99	1	434	1	425	1.0e-84	307	COG0823	Periplasmic component of the Tol biopolymer transport system	425
643628599	156	40.15	13	144	2	132	4.0e-32	130	COG0848	Biopolymer transport protein ExbD	137
643628600	232	43.98	19	232	1	216	2.0e-44	172	COG0811	Biopolymer transport protein ExbB/TolQ	216
643628601	132	44.36	1	132	4	135	2.0e-28	117	COG0824	Acyl-CoA thioesterase FadM	137
643628604	265	47.45	8	260	2	254	5.0e-77	280	COG0084	Tat protein secretion system quality control protein TatD (DNase activity)	256
643628605	265	29.67	1	262	1	262	1.0e-41	163	COG1235	Phosphoribosyl 1,2-cyclic phosphodiesterase	269
643628606	312	31.73	1	311	2	307	1.0e-29	123	COG0679	Predicted permease	311
643628607	915	27.02	22	907	12	921	2.0e-47	184	COG5373	Uncharacterized membrane protein	931
643628609	310	50.66	5	307	1	302	3.0e-96	345	COG0181	Porphobilinogen deaminase	307
643628610	343	46.04	3	341	8	346	7.0e-96	344	COG0407	Uroporphyrinogen-III decarboxylase	352
643628612	291	48.97	5	290	3	278	4.0e-98	351	COG0408	Coproporphyrinogen III oxidase	303
643628614	269	31.03	5	259	3	251	8.0e-34	137	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
643628615	333	34.71	42	324	9	299	4.0e-50	192	COG2813	16S rRNA G1207 methylase RsmC	300
643628616	106	57.55	1	106	2	107	3.0e-33	133	COG2127	ATP-dependent Clp protease adapter protein ClpS	107
643628617	237	26.58	3	232	2	229	5.0e-21	95	COG1011	FMN phosphatase YigB, HAD superfamily	229
643628619	52	48.08	1	52	1	52	4.0e-11	59.9	COG3197	Uncharacterized protein, possibly involved in nitrogen fixation	58
643628620	737	42.96	43	737	3	708	0.0e+00	586	COG2217	Cation transport ATPase	713
643628621	152	34.64	3	151	12	162	2.0e-21	95.1	COG5456	Nitrogen fixation protein FixH	166
643628622	477	34.55	20	403	1	353	9.0e-71	261	COG0348	Polyferredoxin	386
643628623	288	28.57	59	216	3	150	1.0e-11	64.2	COG2010	Cytochrome c, mono- and diheme variants	150
643628624	67	42.19	3	66	2	60	1.0e-09	55.2	COG4736	Cbb3-type cytochrome oxidase, subunit 3	60
643628625	241	63.91	6	235	2	224	6.0e-99	353	COG2993	Cbb3-type cytochrome oxidase, cytochrome c subunit	227
643628626	529	70.24	51	517	3	468	0.0e+00	692	COG3278	Cbb3-type cytochrome oxidase, subunit 1	482
643628628	248	31.55	28	230	12	213	2.0e-30	126	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
643628629	371	28.26	1	362	64	413	1.0e-70	260	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
643628630	407	20.76	1	393	1	367	1.0e-20	94.3	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
643628631	543	65.28	12	535	5	531	0.0e+00	767	COG4172	ABC-type microcin C transport system, duplicated ATPase component YejF	534
643628632	368	60.6	1	367	2	341	2.0e-126	445	COG4239	ABC-type microcin C transport system, permease component YejE	341
643628633	362	67.03	1	362	1	364	0.0e+00	552	COG4174	ABC-type microcin C transport system, permease component YejB	364
643628634	645	26.29	22	634	5	561	1.0e-66	248	COG4166	ABC-type oligopeptide transport system, periplasmic component	562
643628635	174	51.61	52	173	10	130	5.0e-30	124	COG3474	Cytochrome c2	135
643628636	252	43.92	1	252	27	279	4.0e-73	267	COG0077	Prephenate dehydratase	279
643628638	317	39.93	14	313	1	279	6.0e-64	237	COG2816	NADH pyrophosphatase NudC, Nudix superfamily	279
643628639	643	29.83	28	569	15	508	3.0e-85	310	COG0737	2',3'-cyclic-nucleotide 2'-phosphodiesterase/5'- or 3'-nucleotidase, 5'-nucleotidase family	517
643628640	582	43.84	9	481	3	472	6.0e-128	451	COG2812	DNA polymerase III, gamma/tau subunits	515
643628641	114	50.47	5	111	1	105	9.0e-20	88.7	COG0718	Conserved DNA-binding protein YbaB (function unknown)	105
643628642	199	50.77	5	199	4	198	1.0e-66	246	COG0353	Recombinational DNA repair protein RecR	198
643628644	248	48.55	4	243	5	230	2.0e-61	228	COG3820	Uncharacterized protein	230
643628645	206	34.78	17	188	45	226	4.0e-33	134	COG3719	Ribonuclease I	249
643628646	328	43.77	7	327	1	325	1.0e-75	276	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
643628647	230	26.11	14	213	32	229	4.0e-25	108	COG5590	Ubiquinone biosynthesis protein COQ9	229
643628649	232	45.54	10	219	25	236	2.0e-55	208	COG0688	Phosphatidylserine decarboxylase	239
643628650	245	36.32	10	230	6	220	6.0e-32	131	COG1183	Phosphatidylserine synthase	234
643628652	152	44.74	1	152	4	154	9.0e-34	136	COG1522	DNA-binding transcriptional regulator, Lrp family	154
643628653	372	65.23	1	371	1	371	0.0e+00	517	COG0686	Alanine dehydrogenase	371
643628654	143	50.71	1	140	4	129	3.0e-35	140	COG1970	Large-conductance mechanosensitive channel	130
643628655	183	32.5	44	163	9	127	9.0e-11	60.3	COG0526	Thiol-disulfide isomerase or thioredoxin	127
643628656	471	57.73	10	468	1	458	0.0e+00	616	COG0165	Argininosuccinate lyase	459
643628660	435	47.74	15	408	1	394	3.0e-113	401	COG0019	Diaminopimelate decarboxylase	394
643628663	223	47.49	1	216	1	215	8.0e-65	240	COG2884	ABC-type ATPase involved in cell division	223
643628664	300	24.05	15	299	11	294	3.0e-22	99.1	COG2177	Cell division protein FtsX	297
643628665	241	29.36	11	238	1	230	3.0e-23	102	COG0204	1-acyl-sn-glycerol-3-phosphate acyltransferase	255
643628667	452	48.77	1	158	2	161	5.0e-38	152	COG1763	Molybdopterin-guanine dinucleotide biosynthesis protein	161
643628668	235	28.89	1	223	5	225	5.0e-25	108	COG1296	Predicted branched-chain amino acid permease (azaleucine resistance)	238
643628669	110	35.24	5	108	3	107	5.0e-07	46.3	COG4392	Branched-chain amino acid transport protein	107
643628672	344	20.62	22	278	9	233	6.0e-15	75.3	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
643628673	562	36.08	33	438	5	386	1.0e-59	224	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
643628674	312	44.93	3	208	5	211	1.0e-59	223	COG0009	tRNA A37 threonylcarbamoyladenosine synthetase subunit TsaC/SUA5/YrdC	211
643628675	195	57.92	3	183	1	183	3.0e-69	254	COG2818	3-methyladenine DNA glycosylase Tag	188
643628676	391	50.25	1	391	1	392	5.0e-91	328	COG0183	Acetyl-CoA acetyltransferase	392
643628677	240	42	1	237	4	250	2.0e-46	179	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
643628679	253	31.39	10	227	11	232	4.0e-40	158	COG4123	tRNA1(Val) A37 N6-methylase TrmN6	248
643628681	331	38.23	10	330	1	321	1.0e-76	279	COG0142	Geranylgeranyl pyrophosphate synthase	322
643628682	155	48.03	13	153	11	162	2.0e-32	132	COG5321	Uncharacterized protein	164
643628686	290	21.03	50	290	28	262	3.0e-12	66.2	COG3137	Putative salt-induced outer membrane protein YdiY	262
643628688	157	36.77	1	153	1	149	5.0e-22	97.3	COG0781	Transcription termination factor NusB	151
643628689	178	41.84	18	154	12	152	7.0e-30	123	COG0054	6,7-dimethyl-8-ribityllumazine synthase (Riboflavin synthase beta chain)	152
643628690	367	35.48	228	361	15	167	2.0e-20	93.8	COG0807	GTP cyclohydrolase II	193
643628690	367	59.2	12	212	3	202	8.0e-78	284	COG0108	3,4-dihydroxy-2-butanone 4-phosphate synthase	203
643628694	198	47.96	1	194	1	191	1.0e-59	222	COG0307	Riboflavin synthase alpha chain	204
643628695	363	30.17	38	267	21	239	4.0e-24	105	COG1596	Periplasmic protein involved in polysaccharide export, contains SLBB domain of the beta-grasp fold	239
643628697	89	40.23	1	86	7	92	7.0e-14	68.7	COG2938	Succinate dehydrogenase flavin-adding protein, antitoxin component of the CptAB toxin-antitoxin module	94
643628699	400	45.57	6	400	1	393	8.0e-114	403	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
643628700	451	36.43	6	446	11	443	8.0e-61	228	COG0534	Na+-driven multidrug efflux pump	455
643628702	336	60.64	48	296	22	270	3.0e-100	358	COG2326	Polyphosphate kinase 2, PPK2 family	270
643628703	559	27.66	275	553	1	275	2.0e-07	51.2	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
643628704	219	31.7	2	219	1	210	2.0e-22	99.5	COG0625	Glutathione S-transferase	211
643628705	651	48.14	9	651	2	635	0.0e+00	817	COG0187	DNA gyrase/topoisomerase IV, subunit B	635
643628706	393	49.48	2	387	15	357	8.0e-117	413	COG1312	D-mannonate dehydratase	362
643628707	773	58.02	8	767	9	769	0.0e+00	956	COG2183	Transcriptional accessory protein Tex/SPT6	780
643628709	221	42.99	1	220	1	220	5.0e-68	250	COG1136	ABC-type lipoprotein export system, ATPase component	226
643628710	428	37.24	7	428	1	408	3.0e-87	315	COG4591	ABC-type transport system, involved in lipoprotein release, permease component	408
643628711	445	41.68	1	438	1	498	0.0e+00	475	COG0442	Prolyl-tRNA synthetase	500
643628713	375	31.34	28	362	18	349	7.0e-43	168	COG0628	Predicted PurR-regulated permease PerM	355
643628715	728	51	20	711	3	694	0.0e+00	858	COG0855	Polyphosphate kinase	696
643628717	513	28.15	26	453	1	439	3.0e-73	269	COG0248	Exopolyphosphatase/pppGpp-phosphohydrolase	492
643628719	158	42.94	1	158	3	165	9.0e-32	129	COG1247	L-amino acid N-acyltransferase YncA	169
643628720	227	21.84	51	221	1	173	1.0e-18	86.9	COG1076	DnaJ-domain-containing proteins 1	174
643628723	277	22.05	17	248	16	262	1.0e-09	57.3	COG4542	Protein involved in propanediol utilization, and related proteins (includes coumermycin biosynthetic...	293
643628724	324	29.23	1	321	5	350	4.0e-42	165	COG0079	Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase	356
643628725	380	31.86	20	350	18	346	6.0e-49	188	COG0535	Radical SAM superfamily enzyme, MoaA/NifB/PqqE/SkfB family	347
643628727	255	37.93	11	241	1	231	8.0e-48	183	COG5424	Pyrroloquinoline quinone (PQQ) biosynthesis protein C	242
643628728	300	22.92	1	288	3	256	6.0e-15	75.1	COG1235	Phosphoribosyl 1,2-cyclic phosphodiesterase	269
643628729	335	27.45	24	323	1	297	4.0e-24	105	COG0583	DNA-binding transcriptional regulator, LysR family	297
643628730	139	38.71	1	122	1	122	4.0e-26	110	COG3795	Uncharacterized conserved protein	123
643628731	481	52.57	1	481	1	485	0.0e+00	575	COG1492	Cobyric acid synthase	486
643628733	441	35.76	4	439	11	462	3.0e-99	355	COG0008	Glutamyl- or glutaminyl-tRNA synthetase	472
643628734	136	42.75	2	132	3	132	2.0e-27	114	COG3824	Predicted Zn-dependent protease, minimal metalloprotease (MMP)-like domain	136
643628735	309	22.81	87	308	17	238	2.0e-14	73	COG0491	Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II	252
643628736	85	41.89	14	84	12	85	7.0e-13	65.3	COG1872	Uncharacterized conserved protein YggU, UPF0235/DUF167 family	102
643628737	379	37.88	1	355	2	340	7.0e-69	254	COG0123	Acetoin utilization deacetylase AcuC or a related deacetylase	340
643628738	355	38.64	5	355	1	313	1.0e-74	273	COG2355	Zn-dependent dipeptidase, microsomal dipeptidase homolog	313
643628739	252	50.2	2	249	1	252	7.0e-82	297	COG1124	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	252
643628740	274	52.24	3	264	1	268	2.0e-95	342	COG0444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component	316
643628741	300	52.11	18	300	6	288	9.0e-77	280	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
643628742	356	43.81	23	353	6	316	2.0e-82	299	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
643628743	538	26.74	9	538	10	553	1.0e-66	247	COG0747	ABC-type transport system, periplasmic component	556
643628744	192	26.83	7	192	4	207	5.0e-12	64.6	COG0778	Nitroreductase	207
643628745	230	20	5	224	12	239	9.0e-15	74.1	COG2981	Uncharacterized protein involved in cysteine biosynthesis	250
643628746	93	34.57	1	81	1	81	3.0e-09	53.4	COG5454	Predicted secreted protein	89
643628750	237	27.12	30	199	11	187	1.0e-17	83.5	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
643628751	591	49.75	4	590	1	585	0.0e+00	805	COG0173	Aspartyl-tRNA synthetase	585
643628752	189	26.98	2	182	41	255	6.0e-16	77.4	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
643628755	1113	66.59	17	429	1	397	0.0e+00	557	COG0458	Carbamoylphosphate synthase large subunit	400
643628757	453	41.27	1	453	28	481	2.0e-116	413	COG0513	Superfamily II DNA and RNA helicase	513
643628759	169	25.97	6	164	5	176	6.0e-16	77.2	COG3038	Cytochrome b561	181
643628760	256	28.83	3	256	9	281	1.0e-15	77	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
643628762	431	68.33	10	429	2	413	0.0e+00	679	COG0112	Glycine/serine hydroxymethyltransferase	413
643628764	246	29.96	3	245	30	275	4.0e-47	181	COG0061	NAD kinase	281
643628765	225	48.63	1	181	2	184	4.0e-64	237	COG0193	Peptidyl-tRNA hydrolase	190
643628766	104	40.62	1	96	2	94	3.0e-19	86.9	COG2329	Heme-degrading monooxygenase HmoA and related ABM domain proteins	105
643628767	203	41.3	8	99	4	93	2.0e-18	86.1	COG1825	Ribosomal protein L25 (general stress protein Ctc)	93
643628769	396	40	16	395	1	357	5.0e-98	351	COG1304	FMN-dependent dehydrogenase, includes L-lactate dehydrogenase and type II isopentenyl diphosphate isomerase	360
643628770	366	40.66	15	359	14	372	1.0e-58	220	COG3448	CBS-domain-containing membrane protein	382
643628771	263	52.09	1	263	1	262	4.0e-86	311	COG0159	Tryptophan synthase alpha chain	265
643628773	375	58.71	11	375	1	372	0.0e+00	493	COG0012	Ribosome-binding ATPase YchF, GTP1/OBG family	372
643628774	484	45.72	7	342	1	333	3.0e-99	355	COG0836	Mannose-1-phosphate guanylyltransferase	333
643628774	484	51.2	353	477	3	127	1.0e-35	144	COG0662	Mannose-6-phosphate isomerase, cupin superfamily	127
643628775	458	34.48	6	456	9	464	3.0e-91	329	COG1109	Phosphomannomutase	464
643628778	392	36.72	1	383	4	404	4.0e-93	335	COG2081	Predicted flavoprotein YhiN	408
643628780	330	22.19	22	330	19	334	7.0e-19	88.1	COG1466	DNA polymerase III, delta subunit	334
643628781	162	23.12	11	159	12	171	2.0e-06	45.4	COG5468	Predicted secreted (periplasmic) protein	172
643628782	847	47.44	1	847	2	814	0.0e+00	956	COG0495	Leucyl-tRNA synthetase	814
643628785	717	26.58	120	336	19	236	8.0e-10	59.6	COG3063	Tfp pilus assembly protein PilF	250
643628786	221	43.95	2	215	7	228	3.0e-67	248	COG0325	Uncharacterized pyridoxal phosphate-containing protein, affects Ilv metabolism, UPF0001 family	228
643628788	362	56.08	173	361	6	192	5.0e-55	208	COG0807	GTP cyclohydrolase II	193
643628789	228	44.78	5	228	1	227	2.0e-50	192	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
643628790	262	37.08	5	262	3	261	2.0e-65	242	COG0708	Exonuclease III	261
643628791	207	20.29	1	207	1	200	1.0e-08	53.1	COG1309	DNA-binding transcriptional regulator, AcrR family	201
643628793	325	31.46	79	255	1	176	3.0e-28	119	COG1633	Rubrerythrin	176
643628794	309	29.58	1	308	2	309	1.0e-26	114	COG0679	Predicted permease	311
643628795	276	36.16	1	275	7	313	1.0e-63	236	COG0627	S-formylglutathione hydrolase FrmB	316
643628796	162	43.05	1	151	1	150	4.0e-39	153	COG1671	Uncharacterized conserved protein YaiI, UPF0178 family	150
643628797	303	34.43	8	296	10	314	2.0e-51	196	COG2423	Ornithine cyclodeaminase/archaeal alanine dehydrogenase, mu-crystallin family	330
643628798	214	26.89	22	211	55	266	2.0e-10	59.6	COG3336	Cytochrome c oxidase assembly factor CtaG	299
643628800	416	50.25	16	414	14	413	1.0e-109	390	COG5379	S-adenosylmethionine:diacylglycerol 3-amino-3-carboxypropyl transferase	414
643628803	317	22.26	1	284	1	292	2.0e-10	60.3	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
643628804	369	53.49	1	368	1	348	7.0e-118	417	COG0473	Isocitrate/isopropylmalate dehydrogenase	348
643628807	201	55.22	1	201	1	189	1.0e-75	275	COG0066	3-isopropylmalate dehydratase small subunit	191
643628808	174	30.18	4	172	19	185	1.0e-08	53.2	COG3247	Uncharacterized membrane protein HdeD, DUF308 family	185
643628809	475	58.3	3	468	1	423	0.0e+00	636	COG0065	Homoaconitase/3-isopropylmalate dehydratase large subunit	423
643628812	106	51.06	2	95	11	104	4.0e-32	129	COG0799	Ribosomal silencing factor RsfS, regulates association of 30S and 50S subunits	115
643628813	155	42.86	1	154	1	155	3.0e-41	160	COG1576	23S rRNA pseudoU1915 N3-methylase RlmH	155
643628814	151	58.9	7	149	7	147	2.0e-44	171	COG0328	Ribonuclease HI	154
643628818	390	39.44	1	390	2	388	6.0e-114	404	COG1168	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities	388
643628819	177	47.31	1	167	2	168	7.0e-57	213	COG0242	Peptide deformylase	168
643628820	163	44.51	1	162	1	164	5.0e-45	173	COG0242	Peptide deformylase	168
643628821	167	44.31	1	164	2	168	2.0e-42	164	COG0242	Peptide deformylase	168
643628822	302	49.67	1	297	2	307	1.0e-100	359	COG0223	Methionyl-tRNA formyltransferase	307
643628823	1151	32.63	1	1150	1	1163	0.0e+00	518	COG1196	Chromosome segregation ATPase	1163
643628824	294	19.66	4	287	3	292	2.0e-06	47.2	COG0697	Permease of the drug/metabolite transporter (DMT) superfamily	292
643628825	266	37.18	48	264	9	241	3.0e-50	192	COG4121	tRNA U34 5-methylaminomethyl-2-thiouridine-forming methyltransferase MnmC	252
643628826	353	25.81	5	339	6	375	3.0e-22	99.6	COG0665	Glycine/D-amino acid oxidase (deaminating)	387
643628827	653	27.81	350	647	1	296	1.0e-20	95.6	COG0741	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)	296
643628828	281	51.06	1	281	13	296	9.0e-87	313	COG0329	Dihydrodipicolinate synthase/N-acetylneuraminate lyase	299
643628829	157	54	7	156	3	151	6.0e-48	183	COG0691	tmRNA-binding protein	153
643628830	282	43.97	1	282	5	283	6.0e-81	294	COG2897	3-mercaptopyruvate sulfurtransferase SseA, contains two rhodanese domains	285
643628831	394	48.23	1	392	1	396	0.0e+00	465	COG1448	Aspartate/tyrosine/aromatic aminotransferase	396
643628832	450	52.21	42	449	1	403	2.0e-115	409	COG0004	Ammonia channel protein AmtB	409
643628833	112	61.61	1	112	1	112	7.0e-34	135	COG0347	Nitrogen regulatory protein PII	112
643628835	755	39.18	69	738	10	659	0.0e+00	508	COG0744	Membrane carboxypeptidase (penicillin-binding protein)	661
643628836	207	22.61	18	207	8	202	4.0e-18	84.9	COG2854	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, periplasmic MlaC component	202
643628837	262	36.59	17	255	6	247	3.0e-45	175	COG2853	ABC-type transporter Mla maintaining outer membrane lipid asymmetry, lipoprotein component MlaA	250
643628838	578	48.73	12	563	13	564	0.0e+00	608	COG4618	ABC-type protease/lipase transport system, ATPase and permease components	580
643628839	433	19.54	1	416	2	347	2.0e-07	50.7	COG1566	Multidrug resistance efflux pump	352
643628840	152	31.97	6	152	1	129	1.0e-15	75.7	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
643628841	256	33.33	12	240	7	236	8.0e-29	120	COG0584	Glycerophosphoryl diester phosphodiesterase	257
643628842	392	56.96	3	388	5	386	0.0e+00	468	COG3146	Predicted N-acyltransferase	387
643628843	205	32.69	4	198	1	208	9.0e-27	113	COG0625	Glutathione S-transferase	211
643628844	92	48.89	1	90	11	96	1.0e-25	107	COG2154	Pterin-4a-carbinolamine dehydratase	101
643628845	162	41.57	1	162	1	165	3.0e-43	167	COG0678	Peroxiredoxin	165
643628847	184	44.5	1	182	2	184	1.0e-42	166	COG0742	16S rRNA G966 N2-methylase RsmD	187
643628848	214	34.7	1	213	1	217	1.0e-36	146	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
643628850	297	39.8	1	295	1	303	6.0e-82	297	COG0803	ABC-type Zn uptake system ZnuABC, Zn-binding component ZnuA	303
643628851	297	50.2	16	266	5	254	2.0e-87	316	COG1121	ABC-type Mn2+/Zn2+ transport system, ATPase component	254
643628852	286	43.33	6	274	5	274	1.0e-48	186	COG1108	ABC-type Mn2+/Zn2+ transport system, permease component	274
643628853	282	45.62	1	273	1	274	7.0e-47	181	COG1108	ABC-type Mn2+/Zn2+ transport system, permease component	274
643628854	202	50	5	200	7	202	6.0e-54	203	COG4566	Two-component response regulator, FixJ family, consists of REC and HTH domains	202
643628856	334	43.03	2	330	1	329	4.0e-88	318	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
643628857	227	30.11	1	186	8	161	4.0e-19	88.1	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
643628858	441	41.98	47	439	1	379	6.0e-92	331	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
643628859	206	39.44	1	206	6	218	3.0e-26	111	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
643628860	250	43.22	1	197	1	198	6.0e-41	161	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
643628862	447	34.88	10	447	6	454	5.0e-77	281	COG0312	Predicted Zn-dependent protease or its inactivated homolog	454
643628863	258	34.73	5	256	4	259	4.0e-42	165	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
643628865	285	40.4	38	281	1	249	6.0e-51	194	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
643628867	349	43.93	131	342	1	214	1.0e-42	167	COG0811	Biopolymer transport protein ExbB/TolQ	216
643628868	141	43.28	1	134	1	134	2.0e-37	148	COG0848	Biopolymer transport protein ExbD	137
643628869	294	22.97	69	285	16	235	3.0e-09	55.9	COG0810	Periplasmic protein TonB, links inner and outer membranes	244
643628870	272	53.39	13	260	3	253	7.0e-88	317	COG0024	Methionine aminopeptidase	255
643628871	243	40.27	6	222	3	227	4.0e-55	207	COG1058	Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA	255
643628873	310	30.99	138	308	21	188	4.0e-22	98.8	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
643628874	301	34.22	3	298	2	296	9.0e-40	157	COG0583	DNA-binding transcriptional regulator, LysR family	297
643628877	317	55.25	1	291	1	293	3.0e-110	391	COG0777	Acetyl-CoA carboxylase beta subunit	294
643628878	424	43.55	1	424	2	422	1.0e-107	383	COG0285	Folylpolyglutamate synthase/Dihydropteroate synthase	427
643628879	162	23.97	8	147	5	140	1.0e-06	46.1	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
643628880	448	44.3	3	388	1	389	7.0e-99	354	COG0793	C-terminal processing protease CtpA/Prc, contains a PDZ domain	406
643628881	370	22.84	4	367	19	420	2.0e-29	123	COG4942	Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB	420
643628882	506	54.6	2	505	1	508	0.0e+00	625	COG0696	Phosphoglycerate mutase (BPG-independent, AlkP superfamily)	509
643628883	425	38.48	6	420	7	437	4.0e-119	421	COG0621	tRNA A37 methylthiotransferase MiaB	437
643628884	279	43.54	12	273	3	272	5.0e-70	257	COG0253	Diaminopimelate epimerase	272
643628886	1078	15.41	222	962	147	786	4.0e-16	81.1	COG1002	Type II restriction/modification system, DNA methylase subunit YeeA	786
643628895	334	28.66	1	311	3	296	4.0e-24	105	COG4643	Uncharacterized domain associated with phage/plasmid primase	366
643628896	471	28.85	10	339	55	412	3.0e-43	169	COG1061	Superfamily II DNA or RNA helicase	442
643628899	59	61.4	3	59	11	67	1.0e-13	67.6	COG3311	Predicted DNA-binding transcriptional regulator AlpA	70
643628901	432	22.73	110	357	14	272	5.0e-09	56	COG4974	Site-specific recombinase XerD	300
643628902	558	31.52	24	522	1	499	2.0e-70	260	COG0366	Glycosidase	505
643628904	259	31.7	1	259	2	263	1.0e-47	183	COG1801	Uncharacterized conserved protein YecE, DUF72 family	263
643628905	335	24.46	2	274	8	279	2.0e-22	100	COG0715	ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component	335
643628906	297	46.09	2	257	1	247	1.0e-72	266	COG1116	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component	248
643628907	254	30.98	1	253	6	258	2.0e-33	135	COG0600	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component	258
643628908	460	35.89	10	458	1	444	1.0e-111	397	COG0161	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase	449
643628909	294	63.96	1	282	5	287	0.0e+00	464	COG0788	Formyltetrahydrofolate hydrolase	287
643628910	541	22.03	40	393	39	380	7.0e-16	79.1	COG2814	Predicted arabinose efflux permease, MFS family	394
643628911	344	44.38	11	342	6	340	4.0e-81	294	COG3569	DNA topoisomerase IB	354
643628913	174	25.29	7	173	8	169	2.0e-06	45.8	COG3652	Predicted outer membrane protein	170
643628914	470	44.28	1	460	14	482	0.0e+00	496	COG0380	Trehalose-6-phosphate synthase	486
643628915	260	32.91	29	258	20	251	9.0e-40	157	COG1877	Trehalose-6-phosphatase	266
643628918	294	32.62	1	274	11	288	1.0e-33	137	COG1305	Transglutaminase-like enzyme, putative cysteine protease	319
643628919	794	32.55	514	787	1	298	6.0e-49	189	COG2307	Uncharacterized conserved protein, Alpha-E superfamily	313
643628919	794	41.15	26	501	13	488	0.0e+00	529	COG2308	Uncharacterized conserved protein, circularly permuted ATPgrasp superfamily	488
643628920	1107	29.77	1	289	9	302	2.0e-41	165	COG1305	Transglutaminase-like enzyme, putative cysteine protease	319
643628920	1107	58.06	284	1107	1	808	0.0e+00	1088	COG4196	Uncharacterized conserved protein, DUF2126 family	808
643628921	523	37.85	3	514	1	503	2.0e-87	317	COG0737	2',3'-cyclic-nucleotide 2'-phosphodiesterase/5'- or 3'-nucleotidase, 5'-nucleotidase family	517
643628922	112	57.8	2	109	5	113	7.0e-32	128	COG3502	Uncharacterized conserved protein, DUF952 family	115
643628923	354	42.81	43	346	1	305	6.0e-77	281	COG0167	Dihydroorotate dehydrogenase	310
643628927	430	28.8	37	410	1	326	1.0e-49	191	COG0604	NADPH:quinone reductase or related Zn-dependent oxidoreductase	326
643628928	652	38.26	517	630	10	124	4.0e-25	110	COG2185	Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding)	143
643628928	652	45.88	7	489	72	548	0.0e+00	482	COG1884	Methylmalonyl-CoA mutase, N-terminal domain/subunit	548
643628929	462	50.22	1	452	2	454	0.0e+00	506	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
643628930	131	34.19	17	131	11	125	5.0e-13	66.8	COG3686	Uncharacterized conserved protein, MAPEG superfamily	125
643628931	510	52.55	106	509	2	404	4.0e-114	405	COG0508	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component	404
643628932	992	52.09	12	990	1	906	0.0e+00	1270	COG0567	2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes	906
643628933	294	68.37	1	294	1	291	4.0e-120	424	COG0074	Succinyl-CoA synthetase, alpha subunit	293
643628934	397	59.65	1	397	1	386	0.0e+00	517	COG0045	Succinyl-CoA synthetase, beta subunit	387
643628935	320	43.73	4	313	1	308	4.0e-102	364	COG0039	Malate/lactate dehydrogenase	313
643628936	245	23.62	1	243	1	254	2.0e-06	46.5	COG0730	Uncharacterized membrane protein YfcA	258
643628937	285	41.99	10	281	1	280	1.0e-61	229	COG2301	Citrate lyase beta subunit	283
643628938	184	30.11	1	157	1	176	6.0e-12	64.2	COG4094	Uncharacterized membrane protein	219
643628939	67	61.76	1	67	3	70	2.0e-23	100	COG5515	Uncharacterized protein	70
643628940	343	32.65	5	149	13	157	2.0e-14	73.6	COG2030	Acyl dehydratase	159
643628941	127	40.32	8	127	2	125	4.0e-14	70.3	COG2009	Succinate dehydrogenase/fumarate reductase, cytochrome b subunit	132
643628942	123	24.35	9	122	3	117	9.0e-07	45.9	COG2142	Succinate dehydrogenase, hydrophobic anchor subunit	117
643628943	600	53.54	7	577	3	561	0.0e+00	616	COG1053	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	562
643628946	259	51.93	26	257	1	230	5.0e-82	297	COG0479	Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit	234
643628948	216	32.2	12	214	15	218	9.0e-23	100	COG1802	DNA-binding transcriptional regulator, GntR family	230
643628949	228	29.44	9	222	11	221	8.0e-43	167	COG1451	Predicted metal-dependent hydrolase	223
643628953	565	51.39	1	565	7	581	0.0e+00	668	COG1001	Adenine deaminase	584
643628954	318	20.27	17	298	7	283	4.0e-07	49.4	COG2962	Uncharacterized membrane protein RarD, contains two EamA domains	293
643628957	363	38.65	38	362	4	313	9.0e-55	207	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
643628958	332	27.64	4	325	19	322	4.0e-37	149	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
643628959	407	29.84	92	397	1	310	4.0e-37	149	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
643628960	930	37.2	581	744	1	158	7.0e-15	76.6	COG2111	Multisubunit Na+/H+ antiporter, MnhB subunit	162
643628960	930	39.16	3	571	20	582	8.0e-113	401	COG1009	NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit	606
643628961	111	40.35	1	111	1	114	3.0e-18	83.7	COG1006	Multisubunit Na+/H+ antiporter, MnhC subunit	115
643628962	503	31.94	1	495	1	497	4.0e-51	196	COG0651	Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit	504
643628963	163	37.97	5	162	1	157	1.0e-28	119	COG1863	Multisubunit Na+/H+ antiporter, MnhE subunit	158
643628964	89	43.18	1	88	2	89	1.0e-08	51.7	COG2212	Multisubunit Na+/H+ antiporter, MnhF subunit	89
643628965	128	36.36	3	101	2	100	7.0e-15	73	COG1320	Multisubunit Na+/H+ antiporter, MnhG subunit	113
643628966	432	23.39	14	426	5	419	7.0e-34	138	COG1055	Na+/H+ antiporter NhaD or related arsenite permease	424
643628967	184	48.37	1	184	11	194	2.0e-58	218	COG1678	Putative transcriptional regulator, AlgH/UPF0301 family	194
643628969	260	43.2	68	260	1	201	4.0e-38	152	COG1573	Uracil-DNA glycosylase	202
643628970	320	48.08	1	303	3	310	3.0e-103	368	COG0540	Aspartate carbamoyltransferase, catalytic chain	316
643628971	425	43.09	1	425	1	424	3.0e-103	368	COG0044	Dihydroorotase or related cyclic amidohydrolase	430
643628972	201	48.47	11	199	5	200	5.0e-41	161	COG0344	Phospholipid biosynthesis protein PlsY, probable glycerol-3-phosphate acyltransferase	200
643628973	454	48.88	10	454	10	456	0.0e+00	490	COG3572	Gamma-glutamylcysteine synthetase	456
643628975	224	34.65	1	222	32	246	2.0e-42	165	COG1385	16S rRNA U1498 N3-methylase RsmE	246
643628976	310	37.87	9	309	1	289	1.0e-40	160	COG0382	4-hydroxybenzoate polyprenyltransferase	289
643628977	652	37.23	467	602	54	190	8.0e-22	99.1	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
643628980	492	45.57	20	491	1	468	0.0e+00	508	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
643628981	424	37.94	1	423	3	421	6.0e-93	334	COG1253	Hemolysin or related protein, contains CBS domains	429
643628982	179	30.46	4	172	1	174	1.0e-18	86.3	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
643628983	651	28.07	259	642	2	398	4.0e-30	126	COG2304	Secreted protein containing bacterial Ig-like domain and vWFA domain	399
643628984	160	33.33	1	140	5	145	4.0e-24	104	COG0071	Molecular chaperone IbpA, HSP20 family	146
643628986	266	22.48	4	197	10	211	8.0e-12	64.6	COG3591	V8-like Glu-specific endopeptidase	251
643628987	433	32.77	15	420	1	387	1.0e-70	260	COG0247	Fe-S oxidoreductase	388
643628988	358	25.23	2	357	37	455	9.0e-28	118	COG0277	FAD/FMN-containing dehydrogenase	459
643628989	477	38.74	20	469	1	459	6.0e-83	301	COG0277	FAD/FMN-containing dehydrogenase	459
643628990	251	39.57	12	235	5	234	3.0e-44	172	COG3821	Uncharacterized membrane protein	234
643628994	338	41.99	5	326	2	324	7.0e-62	231	COG0714	MoxR-like ATPase	329
643628995	188	56.15	8	188	16	202	1.0e-63	235	COG3816	Uncharacterized protein	205
643628997	59	36.96	5	50	14	58	1.0e-07	48.4	COG4391	Uncharacterized conserved protein, contains Zn-finger domain	62
643628998	937	40.68	11	297	15	304	5.0e-70	259	COG0258	5'-3' exonuclease	310
643628998	937	50.41	330	937	3	593	0.0e+00	721	COG0749	DNA polymerase I - 3'-5' exonuclease and polymerase domains	593
643628999	127	36.52	8	122	2	110	4.0e-20	90.5	COG0537	Diadenosine tetraphosphate (Ap4A) hydrolase or other HIT family hydrolase	138
643629000	330	29.1	6	322	2	301	2.0e-32	133	COG0524	Sugar or nucleoside kinase, ribokinase family	311
643629001	214	56.1	10	214	6	210	5.0e-78	284	COG0177	Endonuclease III	211
643629002	282	35.15	122	276	4	168	2.0e-33	136	COG0350	O6-methylguanine-DNA--protein-cysteine methyltransferase	168
643629003	228	42.54	48	227	10	190	4.0e-36	144	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
643629004	255	36.33	1	242	1	241	1.0e-39	156	COG2186	DNA-binding transcriptional regulator, FadR family	241
643629005	184	32.92	22	182	1	161	1.0e-11	63	COG0711	FoF1-type ATP synthase, membrane subunit b or b'	161
643629006	180	25.81	26	180	2	156	2.0e-10	58.7	COG0711	FoF1-type ATP synthase, membrane subunit b or b'	161
643629008	247	32.88	27	244	26	245	5.0e-37	148	COG0356	FoF1-type ATP synthase, membrane subunit a	246
643629009	111	27.93	2	111	5	115	8.0e-12	62.3	COG5336	FoF1-type ATP synthase assembly protein I	116
643629010	120	34.94	1	82	8	90	7.0e-09	52.9	COG0640	DNA-binding transcriptional regulator, ArsR family	110
643629011	501	43.52	23	497	33	526	2.0e-104	372	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
643629012	269	20.36	1	261	1	255	4.0e-17	82.2	COG1192	Cellulose biosynthesis protein BcsQ	259
643629013	73	37.33	1	73	1	72	3.0e-16	76.4	COG0254	Ribosomal protein L31	75
643629014	124	66.09	1	115	3	113	2.0e-35	141	COG0335	Ribosomal protein L19	115
643629015	249	53.95	10	236	5	227	1.0e-88	319	COG0336	tRNA G37 N-methylase TrmD	240
643629017	176	39.88	8	176	1	173	9.0e-39	153	COG0806	Ribosomal 30S subunit maturation factor RimM, required for 16S rRNA processing	174
643629018	114	64.37	2	88	3	87	2.0e-25	107	COG0228	Ribosomal protein S16	87
643629019	99	31.58	6	99	3	97	9.0e-12	61.9	COG1605	Chorismate mutase	101
643629020	186	26.28	24	168	2	157	3.0e-14	71.9	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
643629021	176	23.27	7	156	2	159	2.0e-12	65.4	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
643629022	178	22.35	6	165	1	170	5.0e-12	64.2	COG1670	Protein N-acetyltransferase, RimJ/RimL family	187
643629023	505	51.66	1	452	1	450	0.0e+00	533	COG0541	Signal recognition particle GTPase	451
643629025	292	30.38	5	288	2	293	2.0e-27	116	COG0583	DNA-binding transcriptional regulator, LysR family	297
643629027	466	26.46	139	458	14	329	6.0e-29	122	COG0642	Signal transduction histidine kinase	336
643629028	470	37.67	4	444	3	454	3.0e-95	342	COG1249	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme	454
643629029	242	29.67	19	200	8	188	8.0e-18	84.2	COG0398	Uncharacterized membrane protein YdjX, TVP38/TMEM64 family, SNARE-associated domain	223
643629031	137	34.91	30	132	7	108	2.0e-11	61.5	COG0594	RNase P protein component	117
643629032	84	42.68	2	83	4	85	2.0e-22	97.3	COG0759	Membrane-anchored protein YidD, putatitve component of membrane protein insertase Oxa1/YidC/SpoIIIJ	92
643629033	292	33.33	23	268	1	242	2.0e-48	185	COG0037	tRNA(Ile)-lysidine synthase TilS/MesJ	298
643629034	508	40.48	245	496	7	255	2.0e-59	223	COG2200	EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant)	256
643629035	623	36.64	261	587	6	300	3.0e-64	239	COG0706	Membrane protein insertase Oxa1/YidC/SpoIIIJ, required for the localization of integral membrane proteins	314
643629036	247	23.86	3	246	2	260	1.0e-16	80.4	COG3217	Uncharacterized conserved protein YcbX, contains MOSC and Fe-S domains	270
643629037	217	44.33	23	216	2	195	5.0e-64	237	COG0218	GTP-binding protein EngB required for normal cell division	200
643629038	246	33.2	3	244	1	250	2.0e-36	145	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
643629039	293	51.7	23	281	1	264	6.0e-76	277	COG0548	Acetylglutamate kinase	265
643629041	168	31.93	2	165	1	163	7.0e-28	116	COG2062	Phosphohistidine phosphatase SixA	163
643629042	146	44.22	1	145	4	149	7.0e-36	143	COG0314	Molybdopterin synthase catalytic subunit	149
643629043	82	44.05	1	82	1	84	6.0e-12	62.3	COG1977	Molybdopterin converting factor, small subunit	84
643629044	221	38.82	1	150	10	158	3.0e-20	92	COG0558	Phosphatidylglycerophosphate synthase	192
643629045	607	48.18	2	604	5	581	0.0e+00	643	COG0322	Excinuclease UvrABC, nuclease subunit	581
643629047	266	33.85	10	254	6	250	3.0e-27	115	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
643629049	250	33.86	1	245	63	311	3.0e-50	192	COG0616	Periplasmic serine protease, ClpP class	317
643629050	296	28.77	1	290	2	289	1.0e-32	133	COG0583	DNA-binding transcriptional regulator, LysR family	297
643629051	155	39.47	4	155	7	158	3.0e-45	174	COG1905	NADH:ubiquinone oxidoreductase 24 kD subunit (chain E)	160
643629052	509	51.91	89	503	1	418	0.0e+00	548	COG1894	NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F)	424
643629053	960	47.83	18	955	1	964	0.0e+00	1256	COG3383	Predicted molibdopterin-dependent oxidoreductase YjgC	978
643629054	271	42.64	1	264	3	266	8.0e-69	254	COG1526	Formate dehydrogenase assembly factor FdhD	266
643629057	405	25.69	1	397	1	377	1.0e-30	127	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
643629058	233	39.22	3	232	1	226	1.0e-42	166	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
643629061	351	25.28	9	330	8	325	5.0e-13	69.1	COG0686	Alanine dehydrogenase	371
643629062	245	38.38	13	192	13	197	4.0e-34	138	COG4221	NADP-dependent 3-hydroxy acid dehydrogenase YdfG	246
643629064	401	20.19	16	393	25	433	5.0e-19	89.1	COG2211	Na+/melibiose symporter or related transporter	467
643629065	249	36.1	8	242	12	249	1.0e-40	159	COG3496	Uncharacterized conserved protein, DUF1365 family	261
643629066	416	42.52	1	413	13	428	2.0e-98	353	COG2907	Predicted NAD/FAD-binding protein	447
643629067	171	32	1	170	2	175	1.0e-22	99	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
643629068	213	34.86	3	212	1	215	3.0e-34	138	COG3806	Anti-sigma factor ChrR, cupin superfamily	216
643629069	378	31.03	55	368	99	413	3.0e-49	189	COG1322	DNA anti-recombination protein (rearrangement mutator) RmuC	448
643629070	616	45.74	13	616	2	638	0.0e+00	609	COG0323	DNA mismatch repair ATPase MutL	638
643629071	435	28.37	11	432	6	435	8.0e-66	244	COG0612	Predicted Zn-dependent peptidase	438
643629072	448	32.88	14	446	6	435	2.0e-72	266	COG0612	Predicted Zn-dependent peptidase	438
643629074	185	30.61	2	148	11	153	1.0e-21	96.4	COG0597	Lipoprotein signal peptidase	167
643629075	529	62.67	6	529	1	515	0.0e+00	747	COG0138	AICAR transformylase/IMP cyclohydrolase PurH	515
643629076	562	28.96	6	541	31	565	2.0e-57	217	COG5360	Uncharacterized conserved protein, heparinase superfamily	566
643629077	410	37.36	90	410	3	354	8.0e-63	234	COG0144	16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family	355
643629079	269	54.75	7	269	5	266	1.0e-82	299	COG0289	Dihydrodipicolinate reductase	266
643629080	137	33.63	11	121	3	112	6.0e-18	83.3	COG0858	Ribosome-binding factor A	118
643629081	245	48.32	6	241	11	247	6.0e-64	237	COG3698	Uncharacterized protein YigE, DUF2233 family	250
643629082	301	39.4	3	301	4	271	2.0e-62	232	COG0130	tRNA U55 pseudouridine synthase TruB, may also work on U342 of tmRNA	271
643629083	358	46.27	15	332	1	300	3.0e-94	338	COG0031	Cysteine synthase	300
643629084	170	33.73	2	167	3	165	2.0e-34	138	COG4333	Uncharacterized protein	167
643629085	93	61.8	5	93	1	89	1.0e-27	114	COG0184	Ribosomal protein S15P/S13E	89
643629086	716	60.14	1	697	1	692	0.0e+00	950	COG1185	Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase)	692
643629090	413	27.16	4	410	1	381	2.0e-28	120	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
643629092	425	22.57	2	417	1	381	7.0e-25	108	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
643629093	546	43.91	1	540	31	572	0.0e+00	487	COG4618	ABC-type protease/lipase transport system, ATPase and permease components	580
643629094	433	25.35	143	415	87	346	2.0e-07	50.7	COG1566	Multidrug resistance efflux pump	352
643629097	928	36.67	1	926	2	957	0.0e+00	893	COG0587	DNA polymerase III, alpha subunit	1139
643629098	417	49.57	2	343	6	339	6.0e-81	294	COG2951	Membrane-bound lytic murein transglycosylase B	343
643629099	752	38.56	1	711	1	704	0.0e+00	560	COG0557	Exoribonuclease R	706
643629100	138	39.53	14	136	23	150	2.0e-20	91.1	COG2153	Predicted N-acyltransferase, GNAT family	155
643629101	380	33.42	4	380	14	408	6.0e-70	258	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
643629103	272	33.73	21	189	2	170	7.0e-32	131	COG2323	Uncharacterized membrane protein YcaP, DUF421 family	224
643629104	277	50.9	7	277	2	270	3.0e-83	301	COG2171	Tetrahydrodipicolinate N-succinyltransferase	271
643629105	274	38.1	69	274	8	196	3.0e-42	165	COG1611	Predicted Rossmann fold nucleotide-binding protein	205
643629107	637	56.14	6	629	1	623	0.0e+00	856	COG1154	Deoxyxylulose-5-phosphate synthase	627
643629108	289	37.65	1	289	1	322	2.0e-51	196	COG0142	Geranylgeranyl pyrophosphate synthase	322
643629109	71	43.33	1	60	10	69	5.0e-09	52.6	COG1722	Exonuclease VII small subunit	81
643629110	307	43.63	1	305	2	312	5.0e-76	278	COG0123	Acetoin utilization deacetylase AcuC or a related deacetylase	340
643629111	223	39.11	1	223	5	228	1.0e-51	196	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
643629112	169	23.68	42	154	13	126	1.0e-09	56.1	COG1846	DNA-binding transcriptional regulator, MarR family	126
643629113	308	38.16	28	307	1	281	1.0e-63	236	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
643629115	135	42.31	3	80	1	78	2.0e-13	68	COG3326	Uncharacterized membrane protein YsdA, DUF1294 family	94
643629116	348	46.63	6	341	1	337	1.0e-85	310	COG1600	Epoxyqueuosine reductase  QueG (queuosine biosynthesis)	337
643629117	225	34.65	8	206	3	201	4.0e-33	134	COG0625	Glutathione S-transferase	211
643629119	1512	56.03	719	1203	2	484	0.0e+00	620	COG0069	Glutamate synthase domain 2	485
643629120	132	32	13	112	25	122	8.0e-16	76.2	COG3791	Uncharacterized conserved protein	133
643629122	475	43.9	25	466	2	450	2.0e-124	439	COG0493	NADPH-dependent glutamate synthase beta chain or related oxidoreductase	457
643629123	262	48.3	1	261	7	270	4.0e-63	235	COG1968	Undecaprenyl pyrophosphate phosphatase UppP	270
643629124	324	33.98	5	259	7	251	5.0e-23	101	COG0702	Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains	275
643629127	307	51.81	2	192	9	201	4.0e-53	202	COG0794	D-arabinose 5-phosphate isomerase GutQ	202
643629128	204	24.35	10	202	28	213	3.0e-09	55.3	COG5375	Uncharacterized protein	216
643629129	163	30.99	30	161	24	164	3.0e-15	74.6	COG1934	Lipopolysaccharide export system protein LptA	173
643629130	253	63.18	16	252	5	243	7.0e-102	363	COG1137	ABC-type lipopolysaccharide export system, ATPase component	243
643629131	191	28.57	1	104	1	104	1.0e-16	79.9	COG1544	Ribosome-associated translation inhibitor RaiA	110
643629132	147	33.1	2	144	8	152	9.0e-28	116	COG1762	Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type)	152
643629133	297	54.61	3	293	1	291	5.0e-108	384	COG1210	UTP-glucose-1-phosphate uridylyltransferase	291
643629134	265	39.85	1	261	2	244	8.0e-52	197	COG1212	CMP-2-keto-3-deoxyoctulosonic acid synthetase	247
643629135	264	46.72	4	257	6	259	9.0e-67	246	COG1218	3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase	276
643629136	204	35.26	8	162	4	153	4.0e-34	138	COG0779	Ribosome maturation factor RimP	153
643629137	535	53.57	164	358	1	190	3.0e-51	196	COG0195	Transcription antitermination factor NusA, contains S1 and KH domains	190
643629138	202	44.83	5	91	7	91	3.0e-16	78.5	COG2740	Predicted RNA-binding protein YlxR, DUF448 family	95
643629139	795	57.87	290	795	1	508	0.0e+00	641	COG0532	Translation initiation factor IF-2, a GTPase	509
643629140	132	34.15	1	123	6	127	3.0e-10	57.7	COG1051	ADP-ribose pyrophosphatase YjhB, NUDIX family	145
643629141	445	49.51	39	445	1	404	3.0e-125	441	COG1364	N-acetylglutamate synthase (N-acetylornithine aminotransferase)	404
643629142	284	22.99	11	266	27	299	5.0e-15	75.1	COG0760	Parvulin-like peptidyl-prolyl isomerase	320
643629143	908	56.06	4	901	1	822	0.0e+00	1049	COG0653	Preprotein translocase subunit SecA (ATPase, RNA helicase)	822
643629144	485	26.92	323	478	36	189	2.0e-14	74.1	COG2885	Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins	190
643629145	254	40.37	37	254	7	224	3.0e-62	232	COG2003	DNA repair protein RadC, contains a helix-hairpin-helix DNA-binding motif	224
643629146	381	56.32	1	378	1	371	0.0e+00	463	COG0484	DnaJ-class molecular chaperone with C-terminal Zn finger domain	371
643629147	639	62.21	1	604	1	579	0.0e+00	696	COG0443	Molecular chaperone DnaK (HSP70)	579
643629149	321	24.11	29	306	7	265	5.0e-17	82.1	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
643629150	247	53.09	3	245	8	241	3.0e-83	301	COG2227	2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase	243
643629151	433	67.51	1	433	2	438	0.0e+00	718	COG2115	Xylose isomerase	438
643629152	478	40.37	1	477	5	497	1.0e-105	377	COG1070	Sugar (pentulose or hexulose) kinase	502
643629154	432	38.5	2	427	1	393	2.0e-94	339	COG4214	ABC-type xylose transport system, permease component	394
643629155	333	47.43	3	324	13	341	9.0e-90	323	COG4213	ABC-type xylose transport system, periplasmic component	341
643629157	407	32.49	66	380	5	312	6.0e-45	175	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
643629158	607	26.93	1	607	6	594	3.0e-75	276	COG0729	Outer membrane translocation and assembly module TamA	594
643629159	1276	23.24	3	1276	15	1278	1.0e-90	328	COG2911	Autotransporter translocation and assembly factor TamB	1278
643629160	278	31.37	11	273	17	283	3.0e-28	119	COG1295	Uncharacterized membrane protein, BrkB/YihY/UPF0761 family (not an RNase)	303
643629164	628	41.42	20	620	1	580	0.0e+00	501	COG1086	NDP-sugar epimerase, includes UDP-GlcNAc-inverting 4,6-dehydratase FlaA1 and capsular polysaccharide biosynthesis protein EpsC	588
643629165	214	32.51	5	204	41	224	5.0e-36	144	COG2148	Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)	226
643629166	277	20.96	4	245	2	268	1.0e-11	63.8	COG0451	Nucleoside-diphosphate-sugar epimerase	314
643629167	147	27.12	22	139	7	123	3.0e-07	48	COG1846	DNA-binding transcriptional regulator, MarR family	126
643629168	276	39.43	1	274	3	266	6.0e-45	174	COG0388	Predicted amidohydrolase	274
643629169	85	61.25	2	80	1	80	8.0e-24	101	COG0695	Glutaredoxin	80
643629170	240	39.83	6	236	5	223	6.0e-36	144	COG1040	Predicted amidophosphoribosyltransferases	225
643629172	372	43.29	40	367	3	320	9.0e-100	357	COG0276	Protoheme ferro-lyase (ferrochelatase)	320
643629177	404	31.35	3	395	7	431	1.0e-68	253	COG2265	tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family	432
643629178	611	35.92	34	601	14	567	2.0e-111	396	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
643629179	614	35.68	23	605	5	567	7.0e-118	418	COG1132	ABC-type multidrug transport system, ATPase and permease component	567
643629180	380	31.49	7	366	5	354	1.0e-51	197	COG0617	tRNA nucleotidyltransferase/poly(A) polymerase	412
643629181	195	22.7	30	161	6	141	6.0e-06	44.2	COG0494	8-oxo-dGTP pyrophosphatase MutT and related house-cleaning NTP pyrophosphohydrolases, NUDIX family	161
643629182	329	31.11	10	320	4	283	3.0e-58	218	COG1281	Redox-regulated molecular chaperone, HSP33 family	286
643629184	418	29.97	133	417	96	366	8.0e-33	135	COG2208	Serine phosphatase RsbU, regulator of sigma subunit	367
643629187	415	45.24	1	345	5	347	2.0e-103	369	COG1171	Threonine dehydratase	347
643629188	408	57.46	1	407	1	403	0.0e+00	585	COG0137	Argininosuccinate synthase	403
643629189	225	31.08	1	222	1	216	3.0e-21	95.1	COG2979	Uncharacterized membrane protein YebE, DUF533 family	225
643629191	299	30.74	22	297	5	280	7.0e-47	181	COG0115	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase	284
643629192	285	35.39	2	285	1	308	2.0e-35	143	COG0524	Sugar or nucleoside kinase, ribokinase family	311
643629193	751	35.58	430	751	1	324	9.0e-70	258	COG0280	Phosphotransacetylase	327
643629193	751	55.01	2	427	12	426	0.0e+00	558	COG0281	Malic enzyme	432
643629194	880	47.72	9	875	4	841	0.0e+00	859	COG0249	DNA mismatch repair ATPase MutS	843
643629195	186	37.77	1	183	7	192	7.0e-34	137	COG0576	Molecular chaperone GrpE (heat shock protein)	193
643629196	356	40.92	8	353	1	343	2.0e-87	316	COG1420	Transcriptional regulator of heat shock response	346
643629197	237	52.52	1	237	8	230	9.0e-70	256	COG0689	Ribonuclease PH	230
643629198	203	45.83	9	199	3	188	6.0e-54	203	COG0127	Inosine/xanthosine triphosphate pyrophosphatase, all-alpha NTP-PPase family	194
643629199	124	34.92	1	124	4	129	8.0e-19	85.7	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
643629200	385	40.1	1	382	27	409	5.0e-99	354	COG0635	Coproporphyrinogen III oxidase or related Fe-S oxidoreductase	416
643629201	117	45.69	1	115	2	117	2.0e-22	98	COG2832	Uncharacterized membrane protein YbaN, DUF454 family	119
643629202	301	39.44	40	286	7	238	3.0e-33	135	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
643629203	253	40.33	2	242	15	253	9.0e-51	193	COG1192	Cellulose biosynthesis protein BcsQ	259
643629205	597	54.45	1	592	26	619	0.0e+00	789	COG0445	tRNA U34 5-carboxymethylaminomethyl modifying enzyme MnmG/GidA	621
643629206	428	39.74	1	428	4	454	1.0e-109	390	COG0486	tRNA U34 5-carboxymethylaminomethyl modifying GTPase MnmE/TrmE	454
643629207	422	70.71	3	422	2	420	0.0e+00	694	COG1158	Transcription termination factor Rho	422
643629208	163	51.37	13	157	3	147	1.0e-36	145	COG1981	Uncharacterized membrane protein	149
643629209	197	32.32	1	197	3	192	3.0e-40	158	COG0424	Predicted house-cleaning NTP pyrophosphatase, Maf/HAM1 superfamily	193
643629210	279	42.7	8	278	7	280	1.0e-75	276	COG0169	Shikimate 5-dehydrogenase	283
643629211	197	35.79	6	192	5	194	2.0e-38	151	COG0237	Dephospho-CoA kinase	201
643629212	229	38.86	1	225	13	236	9.0e-43	166	COG0847	DNA polymerase III, epsilon subunit or related 3'-5' exonuclease	243
643629213	166	34.15	3	166	1	157	3.0e-35	141	COG1952	Preprotein translocase subunit SecB	157
643629214	158	34.75	3	141	5	145	1.0e-21	96	COG3030	Protein affecting phage T7 exclusion by the F plasmid, UPF0716 family	158
643629215	219	24.9	1	217	44	277	1.0e-29	123	COG4395	Predicted lipid-binding transport protein, Tim44 family	281
643629216	341	39.89	3	330	13	365	3.0e-72	265	COG2821	Membrane-bound lytic murein transglycosylase	373
643629217	198	30.81	1	196	1	180	2.0e-22	98.8	COG2840	DNA-nicking endonuclease, Smr domain	184
643629218	137	27.27	13	131	7	137	9.0e-08	49.4	COG0346	Catechol 2,3-dioxygenase or other lactoylglutathione lyase family enzyme	138
643629219	339	46.25	6	332	1	333	2.0e-83	303	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
643629220	352	27.1	7	325	1	274	7.0e-32	131	COG1082	Sugar phosphate isomerase/epimerase	274
643629221	367	29.89	5	360	10	334	5.0e-47	181	COG0673	Predicted dehydrogenase	342
643629222	499	52.02	1	491	4	499	0.0e+00	582	COG1129	ABC-type sugar transport system, ATPase component	500
643629223	316	46.1	2	308	11	307	2.0e-48	186	COG1172	Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component	316
643629224	321	32.1	1	321	3	322	3.0e-43	169	COG1879	ABC-type sugar transport system, periplasmic component, contains N-terminal xre family HTH domain	322
643629225	144	43.1	4	114	12	127	1.0e-18	85.5	COG3794	Plastocyanin	128
643629229	313	33.73	1	307	3	336	2.0e-57	216	COG2070	NAD(P)H-dependent flavin oxidoreductase YrpB, nitropropane dioxygenase family	336
643629231	396	47.14	6	379	4	387	2.0e-118	419	COG0282	Acetate kinase	396
643629232	473	28.27	172	466	4	326	2.0e-42	166	COG0280	Phosphotransacetylase	327
643629232	473	37.93	11	148	12	156	5.0e-22	99.4	COG2030	Acyl dehydratase	159
643629233	252	49.4	2	250	4	252	2.0e-79	288	COG0623	Enoyl-[acyl-carrier-protein] reductase (NADH)	259
643629234	573	44.14	129	572	14	445	4.0e-120	425	COG3243	Poly(3-hydroxyalkanoate) synthetase	445
643629235	312	29.12	45	312	1	281	1.0e-21	97.5	COG0596	Pimeloyl-ACP methyl ester carboxylesterase	282
643629241	551	59.57	7	545	8	560	0.0e+00	624	COG2060	K+-transporting ATPase, A chain	560
643629242	675	67.06	3	675	1	681	0.0e+00	930	COG2216	High-affinity K+ transport system, ATPase chain B	681
643629243	185	53.68	1	183	1	190	3.0e-52	198	COG2156	K+-transporting ATPase, c chain	190
643629244	887	49.27	3	887	1	881	0.0e+00	891	COG2205	K+-sensing histidine kinase KdpD	890
643629245	228	43.17	6	227	2	227	3.0e-55	208	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
643629246	65	31.15	1	61	3	63	3.0e-06	43.4	COG3237	Uncharacterized conserved protein YjbJ, UPF0337 family	67
643629247	575	29.02	336	559	3	221	4.0e-31	130	COG3920	Two-component sensor histidine kinase, HisKA and HATPase domains	221
643629248	194	32.73	15	173	18	182	1.0e-29	122	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
643629250	269	18.39	1	149	9	182	1.0e-06	47	COG1595	DNA-directed RNA polymerase specialized sigma subunit, sigma24 family	182
643629250	269	25.21	145	259	7	124	2.0e-10	59.9	COG0784	CheY chemotaxis protein or a CheY-like REC (receiver) domain	130
643629252	215	29.23	4	197	21	214	2.0e-22	99.1	COG0664	cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases	214
643629254	418	37.5	40	404	35	388	1.0e-70	260	COG2942	Mannose or cellobiose epimerase, N-acyl-D-glucosamine 2-epimerase family	388
643629255	218	36.11	1	213	4	217	1.0e-35	143	COG0546	Phosphoglycolate phosphatase, HAD superfamily	220
643629256	230	36.28	1	222	1	217	8.0e-29	120	COG0637	Beta-phosphoglucomutase or related phosphatase, HAD superfamily	221
643629258	129	40.91	1	110	6	113	8.0e-35	139	COG4451	Ribulose bisphosphate carboxylase small subunit	127
643629259	486	50	15	469	1	429	0.0e+00	569	COG1850	Ribulose 1,5-bisphosphate carboxylase, large subunit, or a RuBisCO-like protein	429
643629260	359	42.73	1	329	1	286	7.0e-93	334	COG0191	Fructose/tagatose bisphosphate aldolase	286
643629261	290	51.03	1	290	1	289	4.0e-111	394	COG3954	Phosphoribulokinase	289
643629262	333	42.58	9	314	16	322	3.0e-94	338	COG0158	Fructose-1,6-bisphosphatase	326
643629263	310	32.06	7	290	1	280	4.0e-26	112	COG0583	DNA-binding transcriptional regulator, LysR family	297
643629264	231	50.64	1	231	3	237	2.0e-73	268	COG0410	ABC-type branched-chain amino acid transport system, ATPase component	237
643629265	233	46.59	1	233	2	250	8.0e-70	257	COG0411	ABC-type branched-chain amino acid transport system, ATPase component	250
643629266	308	37.46	2	302	7	311	2.0e-36	146	COG4177	ABC-type branched-chain amino acid transport system, permease component	314
643629267	292	42.07	6	292	5	294	6.0e-43	168	COG0559	Branched-chain amino acid ABC-type transport system, permease component	297
643629268	426	27.39	33	405	5	360	4.0e-39	156	COG0683	ABC-type branched-chain amino acid transport system, periplasmic component	366
643629270	494	37.21	14	483	11	472	1.0e-106	380	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
643629271	344	24.07	1	317	2	304	2.0e-17	83.4	COG0331	Malonyl CoA-acyl carrier protein transacylase	310
643629272	727	27.63	24	349	18	331	9.0e-39	155	COG1071	TPP-dependent pyruvate or acetoin dehydrogenase subunit alpha	358
643629272	727	31.76	395	727	4	324	9.0e-53	202	COG0022	Pyruvate/2-oxoglutarate/acetoin dehydrogenase complex, dehydrogenase (E1) component	324
643629273	403	38.93	23	403	1	393	3.0e-76	278	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
643629274	304	31.16	15	299	1	290	8.0e-32	131	COG0583	DNA-binding transcriptional regulator, LysR family	297
643629275	377	40.91	4	368	3	375	3.0e-90	325	COG1820	N-acetylglucosamine-6-phosphate deacetylase	380
643629280	285	24.72	18	283	1	243	2.0e-29	123	COG1360	Flagellar motor protein MotB	244
643629281	465	28.03	6	465	4	423	6.0e-49	188	COG1749	Flagellar hook protein FlgE	423
643629282	481	24.1	1	481	1	550	1.0e-37	151	COG1256	Flagellar hook-associated protein FlgK	552
643629284	363	53.2	5	362	7	364	3.0e-112	398	COG1706	Flagellar basal body P-ring protein FlgI	365
643629285	949	24.85	355	679	30	336	7.0e-27	116	COG0642	Signal transduction histidine kinase	336
643629287	238	41.98	1	237	5	247	2.0e-55	208	COG1338	Flagellar biosynthetic protein FliP	248
643629290	542	30.78	16	535	10	542	7.0e-79	288	COG1766	Flagellar biosynthesis/type III secretory pathway M-ring protein FliF/YscJ	545
643629291	162	22.09	1	161	1	158	6.0e-11	60.3	COG1580	Flagellar basal body-associated protein FliL	159
643629294	289	33.57	1	285	3	265	2.0e-54	206	COG1291	Flagellar motor component MotA	266
643629297	688	39.8	1	686	9	693	0.0e+00	589	COG1298	Flagellar biosynthesis pathway, component FlhA	696
643629298	260	31.97	13	252	6	249	1.0e-22	100	COG1684	Flagellar biosynthesis protein FliR	258
643629299	359	35.1	1	359	2	359	3.0e-78	285	COG1377	Flagellar biosynthesis protein FlhB	363
643629302	239	36.44	1	236	1	230	6.0e-49	187	COG2063	Flagellar basal body L-ring protein FlgH	230
643629304	261	46.04	1	261	2	264	1.0e-69	256	COG4786	Flagellar basal body rod protein FlgG	265
643629305	239	31.76	1	226	1	255	5.0e-45	174	COG4786	Flagellar basal body rod protein FlgG	265
643629306	88	36.71	1	79	1	79	3.0e-10	56.7	COG1987	Flagellar biosynthesis protein FliQ	89
643629308	128	35.29	5	127	2	137	2.0e-27	114	COG1558	Flagellar basal body rod protein FlgC	137
643629309	127	32.28	8	126	8	133	4.0e-17	80.3	COG1815	Flagellar basal body rod protein FlgB	133
643629310	436	42.58	4	418	8	421	2.0e-114	406	COG1157	Flagellar biosynthesis/type III secretory pathway ATPase	441
643629314	222	25.45	1	216	1	219	2.0e-24	105	COG1843	Flagellar hook assembly protein FlgD	222
643629315	493	41.35	3	493	9	508	9.0e-119	420	COG0661	Predicted unusual protein kinase regulating ubiquinone biosynthesis, AarF/ABC1/UbiB family	517
643629316	250	51.46	13	250	1	238	1.0e-80	293	COG2226	Ubiquinone/menaquinone biosynthesis C-methylase UbiE	238
643629317	283	49.47	1	283	1	273	5.0e-90	324	COG0266	Formamidopyrimidine-DNA glycosylase	273
643629318	258	45.74	1	255	2	257	9.0e-59	220	COG1024	Enoyl-CoA hydratase/carnithine racemase	257
643629319	92	51.14	1	88	1	88	4.0e-11	59.5	COG0268	Ribosomal protein S20	88
643629320	447	47.84	5	443	8	408	3.0e-119	422	COG0593	Chromosomal replication initiation ATPase DnaA	408
643629321	372	43.55	1	372	1	364	3.0e-86	312	COG0592	DNA polymerase III sliding clamp (beta) subunit, PCNA homolog	364
643629322	363	34.99	4	353	1	360	3.0e-74	272	COG1195	Recombinational DNA repair ATPase RecF	363
643629323	140	29.46	5	127	3	129	1.0e-09	55.7	COG3607	Predicted lactoylglutathione lyase	133
643629324	811	60.21	8	579	3	565	0.0e+00	864	COG0187	DNA gyrase/topoisomerase IV, subunit B	635
643629325	358	41.85	3	357	9	362	5.0e-108	384	COG1485	Predicted ATPase	367
643629326	291	48.57	74	283	3	212	3.0e-54	205	COG0560	Phosphoserine phosphatase	212
643629327	385	31.95	8	376	1	363	4.0e-98	351	COG1932	Phosphoserine aminotransferase	365
643629328	534	48.16	4	327	2	323	5.0e-97	348	COG0111	Phosphoglycerate dehydrogenase or related dehydrogenase	324
643629330	400	43.07	12	400	1	392	6.0e-78	284	COG0183	Acetyl-CoA acetyltransferase	392
643629331	674	44.59	3	673	1	731	0.0e+00	613	COG4953	Membrane carboxypeptidase/penicillin-binding protein PbpC	733
643629332	1808	35.83	318	1808	120	1620	0.0e+00	928	COG2373	Uncharacterized conserved protein YfaS, alpha-2-macroglobulin family	1621
643629334	849	41.43	322	571	98	336	6.0e-41	163	COG0642	Signal transduction histidine kinase	336
643629335	257	45.1	1	255	1	250	8.0e-71	260	COG3022	Cytoplasmic iron level regulating protein YaaA, DUF328/UPF0246 family	253
643629336	681	47.29	5	590	6	584	0.0e+00	632	COG0514	Superfamily II DNA helicase RecQ	590
643629338	175	21.99	26	165	6	133	3.0e-07	48.7	COG0824	Acyl-CoA thioesterase FadM	137
643629339	479	33.26	23	477	8	436	4.0e-75	275	COG2270	MFS-type transporter involved in bile tolerance, Atg22 family	438
643629340	294	41.38	9	293	6	276	3.0e-69	255	COG3770	Murein endopeptidase	284
643629341	296	31.16	34	294	65	337	8.0e-29	121	COG4246	Uncharacterized protein	340
643629342	208	35.16	3	201	24	220	4.0e-23	101	COG1738	Uncharacterized PurR-regulated membrane protein YhhQ, DUF165 family	233
643629344	430	30.39	9	427	1	381	3.0e-71	262	COG1488	Nicotinic acid phosphoribosyltransferase	405
643629345	201	39.8	1	188	1	180	5.0e-33	134	COG1335	Nicotinamidase-related amidase	205
643629347	260	33.99	13	257	2	251	3.0e-38	152	COG1028	NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family	251
643629348	536	38.93	8	496	1	491	5.0e-94	338	COG0366	Glycosidase	505
643629349	412	21.02	34	402	38	386	7.0e-15	75.2	COG2814	Predicted arabinose efflux permease, MFS family	394
643629350	391	23.39	23	316	31	319	6.0e-08	52.5	COG2807	Cyanate permease	395
643629351	342	28.43	44	342	82	379	6.0e-30	125	COG0438	Glycosyltransferase involved in cell wall bisynthesis	381
643629353	340	54.3	2	332	1	333	7.0e-116	410	COG0136	Aspartate-semialdehyde dehydrogenase	334
643629354	214	27.75	11	213	7	203	3.0e-38	152	COG0288	Carbonic anhydrase	207
643629356	461	39.66	4	451	8	476	1.0e-108	386	COG0260	Leucyl aminopeptidase	485
643629358	406	41.03	3	391	5	386	2.0e-86	313	COG3214	Uncharacterized conserved protein YcaQ, contains winged helix DNA-binding domain	400
643629359	392	50.55	23	381	1	349	5.0e-119	421	COG0820	Adenine C2-methylase RlmN of 23S rRNA A2503 and tRNA A37	349
643629361	329	42.86	1	323	7	335	1.0e-66	247	COG4448	L-asparaginase II	339
643629362	279	20.14	1	252	1	288	2.0e-16	80	COG0451	Nucleoside-diphosphate-sugar epimerase	314
643629363	492	23.94	215	470	1	233	1.0e-41	164	COG0775	Nucleoside phosphorylase	234
643629364	95	42.39	4	95	1	92	6.0e-16	75.6	COG0776	Bacterial nucleoid DNA-binding protein	94
643629366	366	57.89	2	359	1	357	0.0e+00	494	COG0082	Chorismate synthase	369
643629367	342	52.85	16	342	5	336	2.0e-97	348	COG4143	ABC-type thiamine transport system, periplasmic component	336
643629368	504	33.59	2	501	10	534	4.0e-47	182	COG1178	ABC-type Fe3+ transport system, permease component	540
643629369	231	51.52	1	230	1	231	4.0e-66	244	COG3840	ABC-type thiamine transport system, ATPase component	231
643629370	287	33.7	9	280	4	250	1.0e-35	143	COG2857	Cytochrome c1	250
643629371	445	46.13	9	406	1	371	7.0e-87	314	COG1290	Cytochrome b subunit of the bc complex	381
643629372	150	35.1	1	150	38	166	4.0e-27	114	COG0723	Rieske Fe-S protein	177
643629373	202	28.37	1	200	1	203	2.0e-15	76	COG0625	Glutathione S-transferase	211
643629377	286	37.36	11	275	11	261	1.0e-47	183	COG3741	N-formylglutamate amidohydrolase	272
643629378	417	48.15	36	379	2	352	1.0e-83	303	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
643629379	293	35.42	12	290	5	290	2.0e-32	132	COG0330	Regulator of protease activity HflC, stomatin/prohibitin superfamily	291
643629382	232	43.48	1	228	9	234	8.0e-44	170	COG0284	Orotidine-5'-phosphate decarboxylase	240
643629383	295	34.62	1	294	7	309	6.0e-41	161	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
643629385	870	55.8	5	852	1	781	0.0e+00	947	COG0542	ATP-dependent Clp protease ATP-binding subunit ClpA	786
643629386	156	55.07	20	156	46	183	4.0e-37	147	COG2335	Uncaracterized surface protein containing fasciclin (FAS1) repeats	187
643629387	301	45.85	47	274	58	271	2.0e-55	209	COG2041	Periplasmic DMSO/TMAO reductase YedYZ, molybdopterin-dependent catalytic subunit	271
643629388	201	48.92	17	201	14	198	1.0e-35	143	COG2717	Periplasmic DMSO/TMAO reductase YedYZ, heme-binding membrane subunit	209
643629397	319	34.92	45	296	5	232	3.0e-17	83.1	COG2801	Transposase InsO and inactivated derivatives	232
643629399	360	34.11	8	340	1	341	7.0e-52	197	COG4782	Esterase/lipase superfamily enzyme	377
643629401	113	36.26	22	110	34	124	6.0e-10	56	COG2207	AraC-type DNA-binding domain and AraC-containing proteins	127
643629402	297	34.74	1	295	53	314	4.0e-41	162	COG1262	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain	314
643629403	509	31.73	63	476	4	467	3.0e-56	213	COG3119	Arylsulfatase A or related enzyme	475
643629405	255	43.87	2	253	1	253	8.0e-77	280	COG1120	ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component	258
643629406	658	39.51	344	658	3	331	6.0e-35	142	COG0609	ABC-type Fe3+-siderophore transport system, permease component	334
643629407	299	23.25	30	291	49	312	8.0e-21	94.6	COG0614	ABC-type Fe3+-hydroxamate transport system, periplasmic component	319
643629408	699	27.13	7	699	30	750	2.0e-62	234	COG4774	Outer membrane receptor for monomeric catechols	750
643629410	377	24.13	68	367	1	308	8.0e-31	128	COG1940	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain	314
643629411	418	19.35	1	414	5	428	8.0e-26	111	COG1653	ABC-type glycerol-3-phosphate transport system, periplasmic component	433
643629412	303	40.27	6	296	1	286	3.0e-53	202	COG1175	ABC-type sugar transport system, permease component	295
643629413	287	35.38	12	286	5	281	1.0e-49	190	COG0395	ABC-type glycerol-3-phosphate transport system, permease component	281
643629414	367	53.2	1	359	1	338	1.0e-121	430	COG3839	ABC-type sugar transport system, ATPase component	338
643629415	313	25.97	13	313	7	298	4.0e-17	82.2	COG2971	BadF-type ATPase, related to human N-acetylglucosamine kinase	301
643629417	339	43.53	6	337	3	342	2.0e-83	302	COG2008	Threonine aldolase	342
643629418	256	38.59	1	241	1	239	4.0e-54	204	COG1349	DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family	253
643629419	264	36.58	8	256	5	260	2.0e-51	195	COG0483	Archaeal fructose-1,6-bisphosphatase or related enzyme of inositol monophosphatase family	260
643629420	527	26.52	4	517	6	543	1.0e-61	231	COG0747	ABC-type transport system, periplasmic component	556
643629421	326	38.02	3	326	1	315	1.0e-66	247	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
643629422	303	43.42	16	295	7	281	6.0e-59	221	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
643629423	617	43.12	10	541	3	537	0.0e+00	493	COG1123	ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain	539
643629424	424	22.04	12	409	2	406	5.0e-29	122	COG0624	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase	409
643629426	314	22.18	44	300	6	257	2.0e-16	80.1	COG0510	Thiamine kinase and related kinases	269
643629429	191	25.84	3	178	11	188	2.0e-06	46.2	COG1309	DNA-binding transcriptional regulator, AcrR family	201
643629430	99	33	1	97	31	129	5.0e-16	75.7	COG0251	Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family	130
643629433	534	23.34	33	369	29	340	3.0e-11	64.2	COG0389	Nucleotidyltransferase/DNA polymerase involved in DNA repair	354
643629437	395	32.36	26	391	46	419	3.0e-46	179	COG1519	3-deoxy-D-manno-octulosonic-acid transferase	419
643629438	332	41.07	4	327	6	333	6.0e-66	244	COG1663	Tetraacyldisaccharide-1-P 4'-kinase	336
643629439	381	50.52	1	377	4	380	5.0e-117	414	COG1804	Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases	396
643629440	223	33.51	36	221	59	244	2.0e-18	86	COG1651	Protein-disulfide isomerase	244
643629441	161	31.47	20	157	41	177	1.0e-13	69.7	COG5389	Uncharacterized protein	181
643629442	336	47.45	12	322	32	340	3.0e-93	334	COG1194	Adenine-specific DNA glycosylase, acts on AG and A-oxoG pairs	342
643629444	372	34.62	15	293	16	298	3.0e-59	222	COG0863	DNA modification methylase	302
643629445	212	55.08	22	204	2	188	6.0e-60	223	COG0164	Ribonuclease HII	199
643629450	365	27.37	2	342	25	393	4.0e-70	258	COG0019	Diaminopimelate decarboxylase	394
643629451	412	43.66	2	406	1	382	2.0e-111	396	COG1748	Saccharopine dehydrogenase, NADP-dependent	389
643629452	638	42.9	7	628	84	708	0.0e+00	522	COG2217	Cation transport ATPase	713
643629454	539	66.16	2	526	4	532	0.0e+00	797	COG4172	ABC-type microcin C transport system, duplicated ATPase component YejF	534
643629455	376	47.98	155	376	65	287	6.0e-64	238	COG1173	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	289
643629456	307	46.52	1	306	1	315	5.0e-81	294	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component	317
643629457	529	34.34	1	529	3	562	2.0e-109	389	COG4166	ABC-type oligopeptide transport system, periplasmic component	562
643629461	777	34.48	5	494	35	513	8.0e-95	342	COG0513	Superfamily II DNA and RNA helicase	513
643629463	201	26.87	1	201	8	201	3.0e-08	52	COG1309	DNA-binding transcriptional regulator, AcrR family	201
643629464	115	55.17	1	114	1	116	9.0e-35	138	COG5507	Uncharacterized  conserved protein YbaA, DUF1428 family	117
643629465	247	37.4	127	247	5	127	1.0e-16	80.3	COG3324	Predicted enzyme related to lactoylglutathione lyase	127
643629466	304	44.59	8	303	14	304	2.0e-67	249	COG3118	Negative regulator of GroEL, contains thioredoxin-like and TPR-like domains	304
643629467	214	43.9	1	201	2	205	1.0e-39	156	COG2802	Uncharacterized protein, similar to the N-terminal domain of Lon protease	221
643629468	59	55.77	8	59	2	53	3.0e-14	69.9	COG2835	Uncharacterized conserved protein YbaR, Trm112 family	60
643629469	409	43.58	6	398	4	387	9.0e-70	257	COG0654	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	387
643629470	441	36.75	1	441	2	468	7.0e-78	284	COG0154	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit or related amidase	475
643629471	392	34.09	8	390	5	389	1.0e-62	234	COG0436	Aspartate/methionine/tyrosine aminotransferase	393
643629473	200	25.76	1	191	2	199	6.0e-24	104	COG2834	Outer membrane lipoprotein-sorting protein	211
643629474	182	45.6	3	180	17	194	4.0e-45	174	COG4764	Uncharacterized protein	197
643629475	108	61.39	6	106	13	113	2.0e-33	133	COG3785	Heat shock protein HspQ	116
643629476	539	38.04	25	539	11	539	0.0e+00	463	COG0405	Gamma-glutamyltranspeptidase	539
643629477	154	23.81	17	116	33	137	2.0e-08	51.9	COG2172	Anti-sigma regulatory factor (Ser/Thr protein kinase)	146
643629478	107	30.1	1	101	3	105	4.0e-08	50	COG1366	Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	117
643629479	150	43.97	3	143	16	154	2.0e-38	151	COG1956	GAF domain-containing protein, putative methionine-R-sulfoxide reductase	163
643629481	224	40.18	14	224	71	289	2.0e-55	209	COG0564	Pseudouridylate synthase, 23S rRNA- or tRNA-specific	289
643629482	243	23.83	1	214	2	165	1.0e-09	56.5	COG0622	Predicted phosphodiesterase	172
643629483	486	45.34	6	473	2	465	5.0e-126	444	COG1012	Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase	472
643629485	478	32.2	1	461	1	459	5.0e-56	212	COG3898	Uncharacterized membrane-anchored protein	531
643629487	236	24.79	1	230	4	245	4.0e-11	62	COG1587	Uroporphyrinogen-III synthase	248
643629488	364	50.29	8	348	4	335	5.0e-110	391	COG0533	tRNA A37 threonylcarbamoyltransferase TsaD	342
643629489	305	45.57	1	305	3	329	3.0e-77	282	COG0240	Glycerol-3-phosphate dehydrogenase	329
643629490	90	39.56	1	88	1	91	3.0e-17	80.3	COG2350	Uncharacterized conserved protein YciI, contains a putative active-site phosphohistidine	92
643629491	137	51.63	1	137	2	152	1.0e-45	175	COG2947	Predicted RNA-binding protein, contains PUA-like domain	156
643629493	401	51.02	7	396	1	391	0.0e+00	495	COG0133	Tryptophan synthase beta chain	396
643629494	470	56.21	7	462	1	420	0.0e+00	635	COG0499	S-adenosylhomocysteine hydrolase	420
643629496	187	27.81	5	186	1	186	8.0e-22	97	COG1896	5'-deoxynucleotidase YfbR and related HD superfamily hydrolases	193
643629498	167	67.86	1	167	15	182	8.0e-62	229	COG4567	Two-component response regulator, ActR/RegA family, consists of REC and Fis-type HTH domains	182
643629499	246	37.69	18	212	5	200	1.0e-36	147	COG1999	Cytochrome oxidase Cu insertion factor, SCO1/SenC/PrrC family	207
643629500	445	21.02	76	401	1	315	1.0e-17	84.8	COG0642	Signal transduction histidine kinase	336
643629502	169	47.01	23	154	5	137	1.0e-33	136	COG0802	tRNA A37 threonylcarbamoyladenosine biosynthesis protein TsaE	149
643629503	341	39.48	15	323	1	343	7.0e-52	197	COG3178	Predicted phosphotransferase, aminoglycoside/choline kinase (APH/ChoK) family	351
643629505	982	32.82	18	678	33	697	1.0e-65	245	COG3893	Inactivated superfamily I helicase	697
643629506	1106	27.75	6	1092	3	1139	0.0e+00	529	COG1074	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)	1139
643629509	185	66.48	9	183	2	175	2.0e-67	248	COG5405	ATP-dependent protease HslVU (ClpYQ), peptidase subunit	178
643629510	433	61.35	1	433	1	444	0.0e+00	615	COG1220	ATP-dependent protease HslVU (ClpYQ), ATPase subunit	444
643629511	510	31.99	3	418	1	393	8.0e-54	205	COG1696	D-alanyl-lipoteichoic acid acyltransferase DltB, MBOAT superfamily	425
643629512	81	27.5	1	80	1	80	5.0e-06	42.6	COG0236	Acyl carrier protein	80
643629513	637	39.27	70	610	19	553	8.0e-123	434	COG3882	Predicted enzyme involved in methoxymalonyl-ACP biosynthesis	574
643629514	246	28.12	6	221	10	225	5.0e-15	74.9	COG0300	Short-chain dehydrogenase	265
643629515	121	29.91	1	111	39	155	6.0e-09	53.2	COG2030	Acyl dehydratase	159
643629520	364	51.34	29	364	22	354	2.0e-99	356	COG5621	Predicted secreted hydrolase	354
643629521	795	21.99	205	791	241	829	6.0e-13	70.3	COG3127	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component	829
643629522	229	42.08	13	229	1	221	2.0e-63	235	COG1136	ABC-type lipoprotein export system, ATPase component	226
643629523	352	42.98	1	352	5	364	3.0e-71	262	COG3490	Uncharacterized protein	366
643629524	329	30.29	5	329	11	359	2.0e-36	146	COG3489	Predicted periplasmic lipoprotein	359
643629525	499	58.91	26	499	7	481	0.0e+00	612	COG3488	Uncharacterized conserved protein with two CxxC motifs, DUF1111 family	481
643629526	161	54.14	1	157	1	157	5.0e-52	197	COG2193	Bacterioferritin (cytochrome b1)	157
643629528	422	62.95	3	422	29	446	0.0e+00	528	COG3487	Uncharacterized iron-regulated protein	446
643629531	227	34.98	22	220	23	221	1.0e-21	97	COG2979	Uncharacterized membrane protein YebE, DUF533 family	225
643629532	298	40.24	51	295	1	246	7.0e-50	191	COG1414	DNA-binding transcriptional regulator, IclR family	246
643629534	163	47.2	5	163	3	163	2.0e-42	165	COG3194	Ureidoglycolate hydrolase (allantoin degradation)	168
643629535	278	56.72	3	270	2	263	9.0e-102	363	COG3257	Uncharacterized protein, possibly involved in glyoxylate utilization	264
643629536	464	26.87	4	292	11	267	2.0e-27	117	COG0726	Peptidoglycan/xylan/chitin deacetylase, PgdA/CDA1 family	267
643629536	464	54.55	299	463	10	171	3.0e-55	209	COG3195	2-oxo-4-hydroxy-4-carboxy--5-ureidoimidazoline (OHCU) decarboxylase	176
643629538	117	63.25	1	117	8	124	4.0e-44	169	COG2351	5-hydroxyisourate hydrolase (purine catabolism), transthyretin-related family	124
643629542	404	32.07	1	399	14	407	1.0e-124	439	COG0538	Isocitrate dehydrogenase	407
643629543	324	36.56	1	318	1	300	6.0e-65	241	COG1893	Ketopantoate reductase	307
643629544	511	37.52	10	505	21	525	2.0e-100	359	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
643629545	228	44.12	1	228	28	263	3.0e-66	244	COG0179	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	266
643629546	327	25.38	9	319	2	325	2.0e-32	133	COG2141	Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)	336
643629547	424	27.78	29	387	1	348	4.0e-39	155	COG0628	Predicted PurR-regulated permease PerM	355
643629549	229	22.98	1	220	1	233	4.0e-06	45	COG2138	Sirohydrochlorin ferrochelatase	245
643629550	825	36.2	288	564	65	336	9.0e-39	156	COG0642	Signal transduction histidine kinase	336
643629551	464	34.06	14	463	4	443	9.0e-101	360	COG0174	Glutamine synthetase	443
643629552	447	32.57	20	447	3	431	4.0e-102	365	COG0001	Glutamate-1-semialdehyde aminotransferase	432
643629553	360	52.82	8	357	1	354	1.0e-122	433	COG0026	Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)	375
643629554	159	62.66	1	158	3	158	2.0e-56	211	COG0041	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase	162
643629555	72	58.33	13	72	9	67	2.0e-08	50.8	COG5481	Uncharacterized protein	67
643629556	155	33.59	21	143	19	145	4.0e-20	90.8	COG0071	Molecular chaperone IbpA, HSP20 family	146
643629557	74	36.76	10	74	19	85	2.0e-07	47.3	COG5568	Uncharacterized protein	85
643629558	158	26.23	1	158	2	180	1.0e-15	75.7	COG3038	Cytochrome b561	181
643629559	568	45.19	24	395	23	387	1.0e-112	400	COG2046	ATP sulfurylase (sulfate adenylyltransferase)	397
643629559	568	51.69	390	567	21	196	5.0e-58	219	COG0529	Adenylylsulfate kinase or related kinase	197
643629560	317	53.75	10	314	2	300	9.0e-93	333	COG0492	Thioredoxin reductase	305
643629561	166	40	1	155	1	154	1.0e-35	142	COG1522	DNA-binding transcriptional regulator, Lrp family	154
643629562	250	44.62	1	250	2	247	8.0e-68	250	COG1496	Copper oxidase (laccase) domain	249
643629563	353	39.35	1	353	1	369	2.0e-85	309	COG1565	SAM-dependent methyltransferase, MidA family	370
643629564	292	42.42	2	290	4	275	4.0e-57	215	COG0682	Prolipoprotein diacylglyceryltransferase	287
643629565	82	41.77	1	79	10	88	2.0e-11	60.4	COG2960	Uncharacterized conserved protein YqiC, BMFP domain	103
643629568	655	37.5	1	646	4	711	0.0e+00	514	COG0643	Chemotaxis protein histidine kinase CheA	716
643629569	163	26.38	1	163	6	164	3.0e-19	88	COG0835	Chemotaxis signal transduction protein	165
643629570	178	30.22	24	162	20	153	8.0e-22	96.9	COG0835	Chemotaxis signal transduction protein	165
643629571	278	37.27	12	278	6	266	3.0e-55	208	COG1352	Methylase of chemotaxis methyl-accepting proteins	268
643629572	346	45.48	1	342	16	348	2.0e-81	296	COG2201	Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains	350
643629575	485	44.2	23	479	1	450	3.0e-124	438	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
643629577	630	37.08	44	602	1	524	0.0e+00	531	COG0365	Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase	528
643629579	759	38.05	437	751	5	319	5.0e-75	276	COG0280	Phosphotransacetylase	327
643629579	759	54.57	2	436	10	432	0.0e+00	543	COG0281	Malic enzyme	432
643629580	134	41.73	7	133	8	134	2.0e-35	141	COG0295	Cytidine deaminase	134
643629581	435	48.28	1	434	2	434	4.0e-124	438	COG0213	Thymidine phosphorylase	435
643629582	398	51.61	1	397	1	392	1.0e-129	456	COG1015	Phosphopentomutase	397
643629583	327	39.94	1	324	9	340	1.0e-70	260	COG1816	Adenosine deaminase	345
643629584	210	57.97	5	210	4	210	9.0e-80	289	COG0035	Uracil phosphoribosyltransferase	210
643629587	549	36.52	20	539	11	526	2.0e-103	370	COG0318	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	534
643629590	423	43.5	47	423	1	375	5.0e-80	292	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component	379
643629591	161	26.71	1	146	9	154	1.0e-13	69.2	COG3090	TRAP-type C4-dicarboxylate transport system, small permease component	177
643629592	324	36.75	1	324	2	332	3.0e-66	245	COG1638	TRAP-type C4-dicarboxylate transport system, periplasmic component	332
643629593	233	30.9	4	228	9	241	5.0e-29	121	COG2186	DNA-binding transcriptional regulator, FadR family	241
643629594	300	33.48	69	292	1	219	4.0e-26	112	COG1802	DNA-binding transcriptional regulator, GntR family	230
643629595	330	33.91	4	328	1	348	7.0e-57	214	COG1063	Threonine dehydrogenase or related Zn-dependent dehydrogenase	350
643629596	366	28.61	2	359	12	388	7.0e-43	168	COG0246	Mannitol-1-phosphate/altronate dehydrogenases	473
643629597	500	48.13	101	500	2	381	3.0e-130	458	COG2721	Altronate dehydratase	381
643629598	597	36.39	16	585	8	601	3.0e-103	369	COG4191	Signal transduction histidine kinase regulating C4-dicarboxylate transport system	603
643629599	439	46.2	1	439	2	459	9.0e-119	420	COG2204	DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains	464
643629600	317	42.9	3	315	2	318	9.0e-79	287	COG2358	TRAP-type uncharacterized transport system, periplasmic component	321
643629601	705	42.92	35	705	22	642	0.0e+00	485	COG4666	TRAP-type uncharacterized transport system, fused permease components	642
643629606	395	39.38	105	263	2	157	4.0e-28	119	COG3436	Transposase	157
643629612	259	28.52	3	251	7	270	1.0e-28	120	COG0338	Site-specific DNA-adenine methylase	274
643629631	400	26.2	17	384	20	387	3.0e-37	149	COG4695	Phage portal protein BeeE	398
643629634	552	27.34	10	537	1	527	7.0e-97	348	COG4626	Phage terminase-like protein, large subunit, contains N-terminal HTH domain	546
643629646	132	46.91	51	131	4	84	8.0e-16	76.1	COG3750	Uncharacterized conserved protein, UPF0335 family	85
643629647	603	23.87	14	232	7	213	3.0e-09	57.2	COG1475	Chromosome segregation protein Spo0J, contains ParB-like nuclease domain	240
643629649	353	24.06	78	329	29	288	2.0e-07	50.2	COG4974	Site-specific recombinase XerD	300
643629651	330	32.02	1	330	3	332	4.0e-64	238	COG1609	DNA-binding transcriptional regulator, LacI/PurR family	333
643629653	202	42	5	201	9	207	1.0e-20	93.4	COG1280	Threonine/homoserine/homoserine lactone efflux protein	208
643629654	350	59.66	36	330	1	294	1.0e-110	393	COG0761	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH	294
643629655	190	43.41	6	184	6	180	8.0e-37	146	COG1432	Uncharacterized conserved protein, LabA/DUF88 family	181
643629657	117	52.7	1	72	1	74	7.0e-12	62.6	COG1758	DNA-directed RNA polymerase, subunit K/omega	74
643629658	705	40.06	1	697	6	700	0.0e+00	741	COG0317	(p)ppGpp synthase/hydrolase, HD superfamily	701
643629659	218	32.02	1	203	1	184	3.0e-26	111	COG3216	Uncharacterized conserved protein, DUF2062 family	184
643629660	249	57.44	4	245	1	242	6.0e-79	287	COG0854	Pyridoxine 5'-phosphate synthase PdxJ	243
643629661	137	45.04	1	131	1	127	7.0e-37	146	COG0736	Phosphopantetheinyl transferase (holo-ACP synthase)	127
643629662	264	27.27	8	128	2	166	1.0e-14	73.9	COG0681	Signal peptidase I	166
643629663	229	44.64	6	225	7	230	6.0e-60	223	COG0571	dsRNA-specific ribonuclease	235
643629664	295	46.23	2	292	10	298	4.0e-100	357	COG1159	GTPase Era, involved in 16S rRNA processing	298
643629665	111	37.96	4	105	2	109	7.0e-13	65.8	COG5447	Uncharacterized protein	115
643629666	239	29.28	2	212	4	225	4.0e-33	134	COG1381	Recombinational DNA repair protein (RecF pathway)	251
643629667	560	44.92	175	560	4	388	3.0e-77	282	COG1960	Acyl-CoA dehydrogenase related to the alkylation response protein AidB	393
643629668	510	61.02	2	508	22	525	0.0e+00	752	COG1866	Phosphoenolpyruvate carboxykinase, ATP-dependent	529
643629670	233	45.49	3	233	2	228	2.0e-56	212	COG0745	DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain	229
643629671	572	30.48	224	572	3	329	1.0e-38	154	COG0642	Signal transduction histidine kinase	336
643629673	298	43.71	5	285	2	286	4.0e-82	298	COG1660	RNase adaptor protein for sRNA GlmZ degradation, contains a P-loop ATPase domain	286
643629674	132	35.34	1	129	1	133	3.0e-20	90.7	COG2893	Phosphotransferase system, mannose/fructose-specific component IIA	143
643629675	89	35.23	1	88	1	88	7.0e-17	79.1	COG1925	Phosphotransferase system, HPr and related phosphotransfer proteins	88
643629676	365	24.94	1	359	5	370	5.0e-14	72.5	COG1835	Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains	386
643629679	308	54.6	1	308	1	310	2.0e-84	305	COG2025	Electron transfer flavoprotein, alpha subunit	313
643629680	253	46.95	1	253	1	260	3.0e-67	248	COG2086	Electron transfer flavoprotein, alpha and beta subunits	260
643629681	192	55.21	1	190	1	184	6.0e-53	200	COG2096	Cob(I)alamin adenosyltransferase	184
643629683	271	27.34	1	271	6	258	1.0e-35	143	COG0300	Short-chain dehydrogenase	265
643629685	767	43.78	18	762	12	739	0.0e+00	751	COG0188	DNA gyrase/topoisomerase IV, subunit A	804
643629687	391	77.02	1	391	1	394	0.0e+00	688	COG0050	Translation elongation factor EF-Tu, a GTPase	394
643629690	64	34.55	5	59	19	73	4.0e-06	43.1	COG0690	Preprotein translocase subunit SecE	73
