LOCUS       c00042_3300000..        6649 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300000234.a:TB_GS09_5DRAFT_10012409.
ACCESSION   c00042_3300000..
VERSION     c00042_3300000..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 10:29:11
            Original ID  :: 3300000234.a:TB_GS09_5DRAFT_10012409
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 6649
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..6649
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1:6286](+)"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2..6286
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..6649
                     /SMILES="NC(C(O)c1ccc(O)cc1)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..6649
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="(cds(Condensation and (AMP-binding or A-OX)) or
                     (Condensation and AMP-binding))"
                     /tool="antismash"
     CDS             2..6286
                     /NRPS_PKS="Domain: AMP-binding (175-568). E-value:
                     3.9e-105. Score: 343.5. Matches aSDomain:
                     nrpspksdomains_ctg42_1_AMP-binding.1"
                     /NRPS_PKS="Domain: nMT (659-875). E-value: 2.7e-85. Score:
                     277.7. Matches aSDomain: nrpspksdomains_ctg42_1_nMT.1"
                     /NRPS_PKS="Domain: PCP (1076-1140). E-value: 2.7e-23.
                     Score: 73.7. Matches aSDomain:
                     nrpspksdomains_ctg42_1_PCP.1"
                     /NRPS_PKS="Domain: Epimerization (1157-1480). E-value:
                     4e-106. Score: 347.2. Matches aSDomain:
                     nrpspksdomains_ctg42_1_Epimerization.1"
                     /NRPS_PKS="Domain: TIGR01720 (1488-1614). E-value: 1.1e-29.
                     Score: 95.0. Matches aSDomain:
                     nrpspksdomains_ctg42_1_TIGR01720.1"
                     /NRPS_PKS="Domain: Condensation_DCL (1645-1946). E-value:
                     9.3e-85. Score: 276.0. Matches aSDomain:
                     nrpspksdomains_ctg42_1_Condensation_DCL.1"
                     /NRPS_PKS="type: NRPS"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     283.9; E-value: 4.4e-86)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg42_1"
                     /sec_met_domain="Condensation (E-value: 2.2e-61, bitscore:
                     194.6, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 1e-114, bitscore:
                     370.3, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1e-17, bitscore:
                     51.7, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="FLEVLRQTRQCVLEALEYQHFPFHWMVDRLGLERSASRQPLAQVG
                     FSLQKPHKLPESARFILNSRDARMNLWGLELEAFPLEQRITQFELTLFFVEDSGKLLGS
                     LEYNTALFAPATIARMAEHYQNLAMAVAQQPSTRIGALAMLGHDEKEVLLQHWAVGAPQ
                     YEFPAIAGFHQLWEHWATRTPQATALHYAGQRFSYGEVNQRANQLAHYLRTHGVSTERL
                     VGIATGRCPEMIVALLAVLKAGGAFVPLDPEYPPERLAFMMEDSGMGWLLARRATLAHL
                     PEVDKLSCQVALLDELDLSGYATENPLPVSGLSSLAYVIYTSGSTGKPKGVMIEHRGLI
                     NFSLGKARILELSPASCMMQMASFSFDASISEITSALGNGAALHLGAGYKVLPDESLVN
                     LLQTDKLSHLIITPSALAVLPRNDLPDLACIVVAGEACPIELVRNWGYSRKFFNAYGPT
                     EATICSSLSLCDPNSAEPPTIGKPFDHIRNYILDPYGQPVPIGVAGELYIGGIGVARGY
                     LNRPELTAQRFLPDPFAPQGGRMYRTGDRARWLANGEIAFLGRMDAQVKLRGFRIELGE
                     IENLLLQHPTVREAAVVLRETQDGDRRLAAYVVPTETVDSALHAQKKEQFLENWQALYE
                     ETYQQIEDMADPTFVVQGWNSSYTGAPIPSEEMRAWVEGITQRIMELKPRRVLEVGCGT
                     GLLLFPIAPHCEMYWGTDYSTAVIAKLQTNVQRVGGLGHVHLEQRFAHDFTGWHVGQFD
                     CVIINSVSQYFPDVEYLRQVLLGLSQCIAPGGVLFVGDVRNYRLLELFHQSVTRFRQPE
                     LMPAQLDQQARQAMLREAELTVDPRFFMAFASEQPAVESIGIEPERSRFRNEMSQFRYH
                     AILRFAAAPGAVADSLAITWQDWQLHPMSASGLARHLAAQRPAGFGLRHVSNARITELQ
                     PGAQAGIDPDEWWELGQALGYQILVSWATGYSDGAYDVCAVRQDYKDAMRAGQQALAVL
                     ARETAGVNHTIWHKYTNTPLRDTGVPPEFIAQLRDYLRQRLPDFMVPAALVVLPVLPRT
                     PGGKLDRNALPAPEIQTRVDGAQPRQPAEELLAGIWCEVLGLPEVGLEDNFFALGGDSI
                     LSIQVVSRARQAGLRLTPQLLLQHQTIASLARASLHQADIRAEQTPVIGMAPLTPIQRW
                     FFAQELAHPHHFNQALLLSVPPESDETALRTALQTLCNHHDALRLRYHRSDKSGVWSQT
                     FAPLLAETQAGTPPWDALLTVYNTPPFPAAIALTEVQQAMATVQSSCDLGQGPLLRALW
                     LRATSGEGRLLLVIHHLAVDGVSWPILLEDLATAYRQYQYSQPIQLPTKTSSYQQWAGQ
                     LADLAEALTSELAWWTPPVHYQHLPADGELAGQALAGTLDNRMGNSQTLHIQLDAERSR
                     ILTQDGPAKTQANMDVLLLAALCRAVREWLADAGQDVDGGGPLLLDMESHGREDLLEDT
                     DVSRTVGWFTALYPVCLDLTGQASMLAWVQAVHAQLARVPNHGVGYGLLRYLHPDPSVR
                     RCLEVWPQARLGFNYLGQFDATFRRAGVFQWANESPGPLWAADNQRYHWLDINGWMINS
                     QLEFSWTYHPGLNAAASIQRLADGFQRALAELADSLRTLTPWPHGVFHLPPADLQTVMQ
                     AMTAADEAFYPLTPTQADMLAHRLQVLDSGLYFTQFQLRLQGALDEALFRQAWQQTASN
                     QPVLRTRFLWQGMETPLQIVGAPQPLCWQSHDFINLSPEDSDLAWQQLLAAERRQGFDP
                     AVAPLCRYVLVRESADVWRFLWNVPHVLMDGWSSPVVLQQVFSSYYAMLQQSQAATVLP
                     APAFVEFLAWRQKLRDNAGKTMLFWRRELQDWPGPAQFPTNAFAPTALTRYVDSVLHLP
                     PEDTAALQNLIRKQAITASTLLQAAWAVLLARHSGQNDIVFGVTVAGRPAELPHVEQRV
                     GMYINTVPVRVKIQPELALKDWLQHLQAAQIERQPHEWAGLAEIQTWLDPEHGRNPEHG
                     RSMAQPLFTTHFRYQNYPLDRGALAANLPDLRITSVEWVDWWHYPLNLMIVPGESLQIW
                     LSHDTQHYATATVETWLAEYAQLLRAVKTGGETRTVGEWLAAT"
     CDS_motif       26..145
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg42_1_0001"
                     /evalue="6.20E-15"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="ctg42_1"
                     /protein_end="48"
                     /protein_start="8"
                     /score="47.5"
                     /tool="antismash"
                     /translation="RQCVLEALEYQHFPFHWMVDRLGLERSASRQPLAQVGFSLQ"
     aSDomain        527..1705
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg42_1_AMP-binding.1"
                     /evalue="3.90E-105"
                     /label="ctg42_1_AMP-binding.1"
                     /locus_tag="ctg42_1"
                     /protein_end="568"
                     /protein_start="175"
                     /score="343.5"
                     /specificity="consensus: bht"
                     /tool="antismash"
                     /translation="WEHWATRTPQATALHYAGQRFSYGEVNQRANQLAHYLRTHGVSTE
                     RLVGIATGRCPEMIVALLAVLKAGGAFVPLDPEYPPERLAFMMEDSGMGWLLARRATLA
                     HLPEVDKLSCQVALLDELDLSGYATENPLPVSGLSSLAYVIYTSGSTGKPKGVMIEHRG
                     LINFSLGKARILELSPASCMMQMASFSFDASISEITSALGNGAALHLGAGYKVLPDESL
                     VNLLQTDKLSHLIITPSALAVLPRNDLPDLACIVVAGEACPIELVRNWGYSRKFFNAYG
                     PTEATICSSLSLCDPNSAEPPTIGKPFDHIRNYILDPYGQPVPIGVAGELYIGGIGVAR
                     GYLNRPELTAQRFLPDPFAPQGGRMYRTGDRARWLANGEIAFLGRMDAQVKLRG"
     aSModule        527..4441
                     /complete
                     /domains="nrpspksdomains_ctg42_1_AMP-binding.1"
                     /domains="nrpspksdomains_ctg42_1_nMT.1"
                     /domains="nrpspksdomains_ctg42_1_PCP.1"
                     /domains="nrpspksdomains_ctg42_1_Epimerization.1"
                     /locus_tags="ctg42_1"
                     /monomer_pairings="bht -> D-NMe-bht"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       713..754
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg42_1_0002"
                     /evalue="1.40E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg42_1"
                     /protein_end="251"
                     /protein_start="237"
                     /score="18.2"
                     /tool="antismash"
                     /translation="LAVLKAGGAFVPLDP"
     CDS_motif       950..1009
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg42_1_0003"
                     /evalue="1.50E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg42_1"
                     /protein_end="336"
                     /protein_start="316"
                     /score="35.9"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGKPKGVMIEHR"
     CDS_motif       1496..1585
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg42_1_0004"
                     /evalue="2.80E-19"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg42_1"
                     /protein_end="528"
                     /protein_start="498"
                     /score="61.1"
                     /tool="antismash"
                     /translation="PIGVAGELYIGGIGVARGYLNRPELTAQRFL"
     CDS_motif       1670..1735
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg42_1_0005"
                     /evalue="1.00E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg42_1"
                     /protein_end="578"
                     /protein_start="556"
                     /score="36.7"
                     /tool="antismash"
                     /translation="FLGRMDAQVKLRGFRIELGEIEN"
     aSDomain        1979..2626
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg42_1_nMT.1"
                     /domain_subtype="nMT"
                     /evalue="2.70E-85"
                     /label="ctg42_1_nMT.1"
                     /locus_tag="ctg42_1"
                     /protein_end="875"
                     /protein_start="659"
                     /score="277.7"
                     /tool="antismash"
                     /translation="GAPIPSEEMRAWVEGITQRIMELKPRRVLEVGCGTGLLLFPIAPH
                     CEMYWGTDYSTAVIAKLQTNVQRVGGLGHVHLEQRFAHDFTGWHVGQFDCVIINSVSQY
                     FPDVEYLRQVLLGLSQCIAPGGVLFVGDVRNYRLLELFHQSVTRFRQPELMPAQLDQQA
                     RQAMLREAELTVDPRFFMAFASEQPAVESIGIEPERSRFRNEMSQFRYHAILRF"
     aSDomain        3230..3421
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg42_1_PCP.1"
                     /evalue="2.70E-23"
                     /label="ctg42_1_PCP.1"
                     /locus_tag="ctg42_1"
                     /protein_end="1140"
                     /protein_start="1076"
                     /score="73.7"
                     /tool="antismash"
                     /translation="EELLAGIWCEVLGLPEVGLEDNFFALGGDSILSIQVVSRARQAGL
                     RLTPQLLLQHQTIASLARAS"
     aSDomain        3473..4441
                     /aSDomain="Epimerization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg42_1_Epimerization.1"
                     /evalue="4.00E-106"
                     /label="ctg42_1_Epimerization.1"
                     /locus_tag="ctg42_1"
                     /protein_end="1480"
                     /protein_start="1157"
                     /score="347.2"
                     /tool="antismash"
                     /translation="APLTPIQRWFFAQELAHPHHFNQALLLSVPPESDETALRTALQTL
                     CNHHDALRLRYHRSDKSGVWSQTFAPLLAETQAGTPPWDALLTVYNTPPFPAAIALTEV
                     QQAMATVQSSCDLGQGPLLRALWLRATSGEGRLLLVIHHLAVDGVSWPILLEDLATAYR
                     QYQYSQPIQLPTKTSSYQQWAGQLADLAEALTSELAWWTPPVHYQHLPADGELAGQALA
                     GTLDNRMGNSQTLHIQLDAERSRILTQDGPAKTQANMDVLLLAALCRAVREWLADAGQD
                     VDGGGPLLLDMESHGREDLLEDTDVSRTVGWFTALYPVCLDLT"
     CDS_motif       3479..3508
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg42_1_0006"
                     /evalue="4.40E-04"
                     /label="NRPS-E1"
                     /locus_tag="ctg42_1"
                     /protein_end="1169"
                     /protein_start="1159"
                     /score="13.2"
                     /tool="antismash"
                     /translation="LTPIQRWFFAQ"
     CDS_motif       3569..3643
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg42_1_0007"
                     /evalue="6.00E-05"
                     /label="C2_LCL_024-062"
                     /locus_tag="ctg42_1"
                     /protein_end="1214"
                     /protein_start="1189"
                     /score="15.5"
                     /tool="antismash"
                     /translation="SDETALRTALQTLCNHHDALRLRYHR"
     CDS_motif       3881..3946
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg42_1_0008"
                     /evalue="1.10E-10"
                     /label="NRPS-E2"
                     /locus_tag="ctg42_1"
                     /protein_end="1315"
                     /protein_start="1293"
                     /score="33.7"
                     /tool="antismash"
                     /translation="LLLVIHHLAVDGVSWPILLEDLA"
     CDS_motif       4385..4435
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg42_1_0009"
                     /evalue="9.20E-09"
                     /label="NRPS-E5"
                     /locus_tag="ctg42_1"
                     /protein_end="1478"
                     /protein_start="1461"
                     /score="27.3"
                     /tool="antismash"
                     /translation="DVSRTVGWFTALYPVCLD"
     aSDomain        4466..4843
                     /aSDomain="TIGR01720"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg42_1_TIGR01720.1"
                     /evalue="1.10E-29"
                     /label="ctg42_1_TIGR01720.1"
                     /locus_tag="ctg42_1"
                     /protein_end="1614"
                     /protein_start="1488"
                     /score="95.0"
                     /tool="antismash"
                     /translation="WVQAVHAQLARVPNHGVGYGLLRYLHPDPSVRRCLEVWPQARLGF
                     NYLGQFDATFRRAGVFQWANESPGPLWAADNQRYHWLDINGWMINSQLEFSWTYHPGLN
                     AAASIQRLADGFQRALAELADSL"
     CDS_motif       4478..4540
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg42_1_0010"
                     /evalue="4.50E-09"
                     /label="NRPS-E6"
                     /locus_tag="ctg42_1"
                     /protein_end="1513"
                     /protein_start="1492"
                     /score="28.5"
                     /tool="antismash"
                     /translation="VHAQLARVPNHGVGYGLLRYLH"
     aSDomain        4937..5839
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg42_1_Condensation_DCL.1"
                     /domain_subtype="Condensation_DCL"
                     /evalue="9.30E-85"
                     /label="ctg42_1_Condensation_DCL.1"
                     /locus_tag="ctg42_1"
                     /protein_end="1946"
                     /protein_start="1645"
                     /score="276.0"
                     /tool="antismash"
                     /translation="AFYPLTPTQADMLAHRLQVLDSGLYFTQFQLRLQGALDEALFRQA
                     WQQTASNQPVLRTRFLWQGMETPLQIVGAPQPLCWQSHDFINLSPEDSDLAWQQLLAAE
                     RRQGFDPAVAPLCRYVLVRESADVWRFLWNVPHVLMDGWSSPVVLQQVFSSYYAMLQQS
                     QAATVLPAPAFVEFLAWRQKLRDNAGKTMLFWRRELQDWPGPAQFPTNAFAPTALTRYV
                     DSVLHLPPEDTAALQNLIRKQAITASTLLQAAWAVLLARHSGQNDIVFGVTVAGRPAEL
                     PHVEQRVGMYINTVPVRVKIQ"
     aSModule        4937..5839
                     /domains="nrpspksdomains_ctg42_1_Condensation_DCL.1"
                     /incomplete
                     /locus_tags="ctg42_1"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       5003..5122
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg42_1_0011"
                     /evalue="1.40E-14"
                     /label="C2_DCL_024-062"
                     /locus_tag="ctg42_1"
                     /protein_end="1707"
                     /protein_start="1667"
                     /score="46.3"
                     /tool="antismash"
                     /translation="GLYFTQFQLRLQGALDEALFRQAWQQTASNQPVLRTRFLWQ"
     CDS_motif       5345..5404
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg42_1_0012"
                     /evalue="1.60E-06"
                     /label="C3_DCL_135-156"
                     /locus_tag="ctg42_1"
                     /protein_end="1801"
                     /protein_start="1781"
                     /score="20.7"
                     /tool="antismash"
                     /translation="HVLMDGWSSPVVLQQVFSSYY"
     CDS_motif       5735..5830
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg42_1_0013"
                     /evalue="8.10E-17"
                     /label="C5_DCL_263-294"
                     /locus_tag="ctg42_1"
                     /protein_end="1943"
                     /protein_start="1911"
                     /score="53.6"
                     /tool="antismash"
                     /translation="DIVFGVTVAGRPAELPHVEQRVGMYINTVPVRV"
     CDS_motif       5879..6031
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg42_1_0014"
                     /evalue="6.90E-08"
                     /label="C67_DCL_14fromHMM"
                     /locus_tag="ctg42_1"
                     /protein_end="2010"
                     /protein_start="1959"
                     /score="24.8"
                     /tool="antismash"
                     /translation="QAAQIERQPHEWAGLAEIQTWLDPEHGRNPEHGRSMAQPLFTTHF
                     RYQNYPL"
     CDS             6301..6648
                     /locus_tag="ctg42_2"
                     /transl_table=11
                     /translation="MELSLFWTAALTYPAVFFTIPLGILLIYWLLVILGTLDLDLLPDL
                     EHGPGHWPAVLGLSEGVPVMIVVSLLVFSGWLISMPATAWLVLSLPGTGLQMLAGTGVL
                     AVAGFLALWLTA"
ORIGIN
        1 attccttgaa gtattgcgcc aaactcgcca atgcgtattg gaagcgctgg aataccagca
       61 tttcccattt cattggatgg tggatcggct gggcctggaa cgcagcgcca gccgtcaacc
      121 cttggcgcaa gtgggattta gtctgcaaaa accacataaa ttgccagaat ctgcgcgctt
      181 tatcctcaac agccgcgatg cgcgcatgaa tctgtggggg ctggaacttg aggcgttccc
      241 gttagaacag cgcatcaccc agtttgaact cacgctattt tttgtggaag acagcggaaa
      301 actgttaggt tcgctggaat acaataccgc tttgtttgcg ccagccacca tcgcgcgtat
      361 ggcagagcac tatcaaaatc tggccatggc cgtggcacaa cagccgtcca cgcggattgg
      421 cgcattggcc atgctgggcc acgacgaaaa agaggtactg ctgcaacact gggcggtggg
      481 cgcgccgcag tatgaattcc cggcaatcgc cggatttcac caactgtggg aacactgggc
      541 aacacgcacg ccgcaagcca cagcgctgca ttacgcaggt caacggttca gctatggcga
      601 agtcaaccaa cgcgccaatc aactggcgca ctacctgcgc acgcatggcg tcagcaccga
      661 acggctggta ggcatcgcca cggggcgttg cccagagatg attgtcgcgt tattggccgt
      721 gctcaaggcg ggtggcgcat tcgtgccgct agacccggaa tatccacccg agcgcttggc
      781 attcatgatg gaagattccg gcatgggctg gttgctggcg cgccgtgcga ctttggccca
      841 tctgccagag gttgacaagt tgtcctgcca agtggcgctc ctggatgaat tggatttgtc
      901 tgggtatgct acggaaaatc ccttgcctgt cagcgggttg tccagtctgg cctatgtcat
      961 ttatacctcg ggttccacgg ggaagcccaa gggggtgatg atcgagcatc gtgggctgat
     1021 taacttttcc ttaggcaagg cgagaatctt agaactctcc cctgccagtt gcatgatgca
     1081 gatggcgtct tttagttttg atgcatctat ttctgaaatt accagcgcgc taggcaatgg
     1141 agcggctttg cacttgggtg ccggttataa agtcctccca gatgaatcgt tagtaaattt
     1201 actgcaaacg gataaactgt ctcatttgat catcacgcct tccgcgttgg ccgtattgcc
     1261 gcgcaatgac ctgcccgatc ttgcttgtat cgtggtagcg ggcgaagcct gccccattga
     1321 gttggtgcgc aactggggct atagccgtaa attttttaat gcgtatggcc ctaccgaagc
     1381 cacaatttgt tctagcctaa gcttatgcga tcccaatagc gccgaaccgc ccaccatagg
     1441 caaaccattt gatcacatcc gcaattacat tttggatcct tatggccaac cggtgccaat
     1501 cggcgtagca ggtgaattgt acattggcgg catcggcgta gcacgcggct atctcaaccg
     1561 tccagaactc acggcgcaac gttttttgcc cgatccgttt gcgccgcaag gcgggcgcat
     1621 gtaccgcacc ggcgaccgtg cgcgctggct ggccaatggt gaaattgcgt ttcttggccg
     1681 catggacgcg caagtcaaac tgcgcggctt ccgtatcgag ctgggcgaaa ttgaaaatct
     1741 gctgttgcag catccgaccg tgcgcgaagc tgcggtggta ctgcgtgaaa cccaagacgg
     1801 cgaccgacgg ttagcggcat atgttgtgcc aacagaaacg gtggacagcg cgctacatgc
     1861 gcagaaaaaa gagcagttcc tagaaaactg gcaagccctt tacgaggaaa cgtaccagca
     1921 aatcgaggac atggcagacc ctacgtttgt ggtgcaaggt tggaatagca gttataccgg
     1981 tgcccccatt ccctcagagg aaatgcgcgc ttgggtggag ggtattacgc aacgaattat
     2041 ggaattaaaa ccgcgccggg tgttggaagt gggctgcggc acaggattgc tgttgttccc
     2101 cattgcgccg cattgtgaga tgtactgggg cacagattat tcaacagcgg ttatcgccaa
     2161 gctgcaaacc aatgtccagc gcgtgggtgg tctaggtcat gtccacctgg aacaacggtt
     2221 tgcccatgat tttactggct ggcatgtagg acaatttgac tgcgttatca tcaactccgt
     2281 cagccaatat tttccagacg tggaatattt acgccaagtt ctgctcggtt tgtcgcaatg
     2341 tatcgcgcct ggcggcgttt tgtttgtagg cgatgtgcgc aactaccgct tgctagagct
     2401 atttcaccag agtgtgacac gtttccgcca gccagaactc atgcccgcac aactggatca
     2461 gcaagcacgg caagccatgc tccgcgaagc ggaattgacc gtggatccac gattttttat
     2521 ggcctttgcg agtgaacaac cggctgtgga atccattggc attgaaccag aacgcagccg
     2581 tttccgcaat gaaatgagcc agttccgcta tcatgccatt ctgcgcttcg ctgctgcccc
     2641 cggtgccgtt gccgattcct tggccatcac ctggcaagac tggcagcttc accccatgtc
     2701 tgcgtcagga ttggcgcgcc acctggctgc gcagcgtcct gctggctttg ggctacgcca
     2761 cgtgagcaac gcgcgcatca cagaactcca acctggcgcg caagctggga tagacccgga
     2821 cgaatggtgg gaactcggcc aagcgctggg ataccagata ttggtaagct gggccaccgg
     2881 ctactcggac ggtgcgtatg acgtgtgtgc ggtacgccaa gactacaaag acgccatgcg
     2941 tgcgggtcag caggcattgg ccgtgctcgc cagggaaaca gcaggggtga accatacaat
     3001 ttggcacaaa tataccaaca ccccgttgcg cgataccggt gtgcccccgg aattcattgc
     3061 acagttgcgc gattatctgc gccaacgtct gcctgatttc atggtgcccg ccgcactggt
     3121 ggttttgccc gtattgccgc gcacgccagg cggcaaattg gaccgcaatg ccttgccagc
     3181 gccggaaata caaacccggg tggatggcgc gcagccacgc caacctgcgg aagaattgct
     3241 ggcaggcatt tggtgcgaag tattgggatt gcctgaagtg ggcttagaag acaatttttt
     3301 tgcgctgggc ggggattcca ttctcagcat ccaggtggtt tcccgcgcgc gccaggcagg
     3361 tttacgcctg acgcctcagt tgttgctaca acaccaaacc atcgccagct tggcgcgcgc
     3421 cagcctacac caggcagaca tccgtgccga gcaaacacca gtcattggca tggcaccgct
     3481 cacgcccatc cagcgctggt tttttgccca ggaattagcc catccccatc attttaacca
     3541 agccctgctg ttatccgtgc cacccgagtc ggacgaaact gccttgcgca cggcattaca
     3601 aacgctatgc aatcatcacg atgcgttgcg cttgcgttac catcgcagcg acaagtccgg
     3661 cgtttggtca cagacctttg caccgttgct agcagaaacg caggcgggaa cgccgccgtg
     3721 ggatgcgttg ttgactgtgt acaacacccc accatttcct gccgccatcg cgctgacaga
     3781 agtgcaacag gctatggcaa cagtccaatc ctcatgcgac ttaggccaag gcccgctgtt
     3841 gcgcgcgctg tggctgcgtg cgacgtctgg cgaaggccgg ttgctgctgg ttattcacca
     3901 tttggcggtg gatggcgtat cctggccaat tttgttggaa gatttggcca ccgcctaccg
     3961 ccaataccaa tatagccaac ccatacaatt gccgactaaa accagctctt accagcaatg
     4021 ggccgggcag ttggcggatt tggccgaggc gttgaccagc gaattggcgt ggtggacgcc
     4081 gcctgtgcac taccagcatt tacctgcgga tggtgagttg gcggggcaag cgctggcagg
     4141 cacgctggac aaccgtatgg gcaatagcca aaccctgcat attcaactgg atgctgaacg
     4201 ttcgcgcata ctgacgcaag acggcccggc caaaacccag gcgaatatgg atgtcctgtt
     4261 attggcggcg ttatgccgtg ccgtgcggga atggctggca gacgcggggc aggacgtgga
     4321 tggcggcggg ccattgttgt tggatatgga aagccatggc cgcgaagacc tgcttgaaga
     4381 caccgatgtg tcgcgcaccg tgggctggtt taccgcgctt tacccggtgt gtttagacct
     4441 cacgggtcaa gcgtctatgc tggcctgggt gcaagcggtg cacgcacaat tggcgcgcgt
     4501 gcccaaccac ggcgtgggat acggactgct gcgctatctt caccccgatc caagcgtgcg
     4561 ccgttgcctg gaagtttggc cgcaagcgcg gctgggcttt aattatctgg gccaattcga
     4621 cgccactttc cgccgtgcgg gcgttttcca gtgggcaaac gaatcacccg gcccgttgtg
     4681 ggctgccgat aaccagcgct accattggtt ggacatcaat ggctggatga tcaacagcca
     4741 attagaattt tcctggacct accatcctgg gttaaacgca gcagccagca ttcagcgctt
     4801 ggcagacgga tttcagcggg cattagcaga attggccgac agcttgcgta cattgacacc
     4861 atggccgcat ggtgtgtttc atttaccacc agcggatttg caaacagtga tgcaggctat
     4921 gacggcggca gatgaggcgt tttatccgct gactccgacg caggccgaca tgttggcgca
     4981 ccgtctgcaa gtgctggaca gcggactgta ttttacccag ttccaattgc gcttgcaggg
     5041 ggcattagat gaagcgctgt tccgccaagc ttggcagcaa actgccagca atcaacctgt
     5101 gttgcgcacg cgcttcctat ggcaaggcat ggaaacgccc ttacaaatcg tgggcgcgcc
     5161 ccaaccacta tgttggcaat cacatgattt tataaattta tcgccagaag acagcgatct
     5221 ggcttggcaa caactgctgg ctgccgaacg caggcaagga ttcgatcctg ctgttgcgcc
     5281 gttatgccgt tatgtactgg tgcgcgaaag cgccgatgtc tggcggtttt tgtggaatgt
     5341 gccacatgta ctgatggacg gctggtcatc gccagtggtg ttgcaacaag ttttttccag
     5401 ctactacgcc atgttgcaac aaagccaagc ggcaacagtg ctgcccgcgc ccgcatttgt
     5461 ggaatttttg gcctggcggc aaaaactacg cgacaatgcc ggaaaaacca tgctgttctg
     5521 gcggcgcgaa ttgcaggatt ggcccggccc agctcagttc ccaacaaatg cattcgcgcc
     5581 aaccgcgctt acacgctacg tggacagtgt actccacctc ccccccgagg acaccgccgc
     5641 gttgcaaaat ctaatccgca aacaggcaat taccgccagc accttgctgc aagccgcgtg
     5701 ggcggtgttg ctggcgcgcc acagcggcca aaacgacatt gtctttggtg tcaccgtggc
     5761 cgggcggcct gcggaattgc cacatgtgga acaacgggta ggcatgtaca tcaacaccgt
     5821 gccagtgcgc gtaaaaatac agccagaact ggcgctgaaa gattggctgc aacacctgca
     5881 agccgcgcaa atcgagcgcc agccgcacga gtgggcggga ttggcggaaa ttcaaacttg
     5941 gctagacccg gaacacgggc gtaacccgga acacgggcgt agcatggcgc aaccgctgtt
     6001 tacgacccac ttccgctacc aaaattaccc gttggacagg ggcgcgctgg ccgcgaacct
     6061 gccggacttg cgcattacct cggtggaatg ggtagactgg tggcattatc cgctcaatct
     6121 tatgattgtt cctggcgaat ccttgcaaat ttggctaagc catgacacac aacattacgc
     6181 cactgccacg gtagaaactt ggttggcgga gtatgcccag ttattgcgcg cagtcaagac
     6241 aggcggcgaa acacgcacgg taggagaatg gctggcagcc acgtaacagg agtaaaccgt
     6301 atggagttat ctttattctg gaccgccgcg ttgacgtatc cggcggtgtt tttcaccatc
     6361 ccgctgggta tcttgctgat ttactggcta ttggtgatac tcggcacgct ggatttggat
     6421 ttgctgcccg atttagagca cggccctggt cattggccag cggtgctggg cttgagcgaa
     6481 ggcgtgccgg tcatgattgt ggtgagcctg ttggtgttca gcggctggct gatcagtatg
     6541 cccgccacgg cctggctggt gctgtccctg ccgggcaccg gcctgcaaat gctggcaggc
     6601 acgggcgtgc tggcagtggc cggatttttg gcgttatggc tgaccgccg
//
