LOCUS       c00228_3300000..       11702 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300000234.a:TB_GS09_5DRAFT_10005712.
ACCESSION   c00228_3300000..
VERSION     c00228_3300000..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 12:27:54
            Original ID  :: 3300000234.a:TB_GS09_5DRAFT_10005712
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 11702
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     aSDomain        1..1101
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg228_1_AMP-binding.1"
                     /evalue="6.80E-100"
                     /label="ctg228_1_AMP-binding.1"
                     /locus_tag="ctg228_1"
                     /protein_end="367"
                     /protein_start="0"
                     /score="326.2"
                     /specificity="consensus: X"
                     /tool="antismash"
                     /translation="YRELNQAANRIAHELLDTYQVQADEIIAVTVERSEQLVIALLAVL
                     KTGAVYLPIDPTYPQDRINYMLNNSCCRLLIVQGQESISSPSLQHIIELPKISSNNLAN
                     PPIRATARDLAFVIYTSGSTGQPKGVMIEHRGFVNMVYDKIHTFKATQRDKVLQFASAS
                     FDASLDETFLALLSGATLVLISKETIQNTQKFAQYLEKQAISICLLPPVYLNALNHHPL
                     PTLRTLMTIGEPAIVEDVQFYAQNKNYFNGYGPTETSICATLYQVEENQWDNHNVPIGK
                     PVVNTAIYVLDSGLNLAPIGIVGEICIAGHGVSRGYLNNPSLTQEKFVDNPFKPGEKMY
                     KTGDLGRWLAEGNLEFLGRTDDQVKISG"
     aSModule        1..3606
                     /complete
                     /domains="nrpspksdomains_ctg228_1_AMP-binding.1"
                     /domains="nrpspksdomains_ctg228_1_PCP.1"
                     /domains="nrpspksdomains_ctg228_1_Epimerization.1"
                     /locus_tags="ctg228_1"
                     /monomer_pairings="X -> D-X"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS             1..4098
                     /NRPS_PKS="Domain: AMP-binding (0-367). E-value: 6.8e-100.
                     Score: 326.2. Matches aSDomain:
                     nrpspksdomains_ctg228_1_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (817-883). E-value: 4.4e-23. Score:
                     73.0. Matches aSDomain: nrpspksdomains_ctg228_1_PCP.1"
                     /NRPS_PKS="Domain: Epimerization (894-1202). E-value:
                     1.4e-129. Score: 424.8. Matches aSDomain:
                     nrpspksdomains_ctg228_1_Epimerization.1"
                     /NRPS_PKS="Domain: TIGR01720 (1207-1363). E-value: 1.5e-44.
                     Score: 143.2. Matches aSDomain:
                     nrpspksdomains_ctg228_1_TIGR01720.1"
                     /NRPS_PKS="type: NRPS-like protein"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     112; E-value: 6.9e-34)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg228_1"
                     /sec_met_domain="Condensation (E-value: 4.2e-65, bitscore:
                     208.6, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 1.8e-117, bitscore:
                     381.2, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 4.6e-14, bitscore:
                     41.7, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="YRELNQAANRIAHELLDTYQVQADEIIAVTVERSEQLVIALLAVL
                     KTGAVYLPIDPTYPQDRINYMLNNSCCRLLIVQGQESISSPSLQHIIELPKISSNNLAN
                     PPIRATARDLAFVIYTSGSTGQPKGVMIEHRGFVNMVYDKIHTFKATQRDKVLQFASAS
                     FDASLDETFLALLSGATLVLISKETIQNTQKFAQYLEKQAISICLLPPVYLNALNHHPL
                     PTLRTLMTIGEPAIVEDVQFYAQNKNYFNGYGPTETSICATLYQVEENQWDNHNVPIGK
                     PVVNTAIYVLDSGLNLAPIGIVGEICIAGHGVSRGYLNNPSLTQEKFVDNPFKPGEKMY
                     KTGDLGRWLAEGNLEFLGRTDDQVKISGHRIELSEIEYALRQHPYIQEVVVAAKGDKAT
                     EKTLSAYFTRKQKVELFPSIAEFYVYDDVVYRSMATDEARNERYRAAFNSLKNKKVVEI
                     GPGPEVILSRLCLEAGAEKIYAIELLEETYRKAQLTLQRLGLEDRIILIHGDATQVELT
                     EKVDYCISEIVGAIGGSEGSAKIINETRHFLHDGRCMIPQRSLTKIAAFSLPTTDFDYH
                     FSPIAAHYVKQIFAQKGYSFDLRLCVKNFNHNALLSNADVFEDLDYTQEITLETTHSIE
                     LVIEKAGVFTGFLVWLTLYTDASHVVDILEQQASWIPVYLPIDLSGIEVQPGDKILATI
                     DRKLCSNGLNPDFFVNGEIIRKNHVPVPFNYASYHDKSLFRATPFYAQLFADGQIPMQP
                     ALTTDDLRNFLIDSLPNYMLPSYFMELAQLPLTPNGKVDKKALPMPEITTVTESHNYAA
                     PRTTMEQKLVEVWSQVLRKEVIGIYDNYFTLGGDSIKAIQIISRLHQEGWAAEVRDIFQ
                     SPTIAELALEIKVLKREIEQDVVTGDVPLSPIQAWFFAQPNPALHHFNQSVLLKSAARL
                     NADRLRTVFEMLQIHHDALRLHYQVAEVLLGYNNLKGLVVRQQNADIDYPVNFQSIDLT
                     NESEPTTKVESYANALHESFNLGQGPLMKAILFHLPQEDQLFIVIHHLVVDSVSWRILL
                     EDLMTAYTHATLGQAIQLPLKTDSFKNYAERLLEHAQSDAVVQEIPYWQAVQSTLVRSL
                     PRDFDTADNCIAETTQFTFALSAMDTQILLTDAHQAYHTRIDDLLLTALALALKQWHSG
                     DKTLIVLEKYGREVLDLNLSRTVGWFTSIYPFVLELPETEDLGYQIKFIKESLRKVPNF
                     GLNYGVLKYLTPPQQKMGLSSQDNVAQLGFNYLGQLDTAEDESSIFTVDWDSVGQGMSP
                     QMPRVHDIDILSWVVDGKLEISLTYHQQRYQLATIQRLATAYEQALRAVITHCQSREGS
                     ELTPDDFTYKGLSLTDLDNLFD"
     protocluster    1..11702
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[0:4098](+)"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1..4098
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..11702
                     /SMILES="NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..11702
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="(cds(Condensation and (AMP-binding or A-OX)) or
                     (Condensation and AMP-binding))"
                     /tool="antismash"
     CDS_motif       124..165
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg228_1_0001"
                     /evalue="1.10E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg228_1"
                     /protein_end="55"
                     /protein_start="41"
                     /score="15.5"
                     /tool="antismash"
                     /translation="LAVLKTGAVYLPIDP"
     CDS_motif       343..402
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg228_1_0002"
                     /evalue="9.10E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg228_1"
                     /protein_end="134"
                     /protein_start="114"
                     /score="33.5"
                     /tool="antismash"
                     /translation="AFVIYTSGSTGQPKGVMIEHR"
     CDS_motif       895..984
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg228_1_0003"
                     /evalue="1.80E-15"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg228_1"
                     /protein_end="328"
                     /protein_start="298"
                     /score="49.0"
                     /tool="antismash"
                     /translation="PIGIVGEICIAGHGVSRGYLNNPSLTQEKFV"
     CDS_motif       1066..1131
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg228_1_0004"
                     /evalue="6.60E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg228_1"
                     /protein_end="377"
                     /protein_start="355"
                     /score="34.2"
                     /tool="antismash"
                     /translation="FLGRTDDQVKISGHRIELSEIEY"
     aSDomain        2452..2649
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg228_1_PCP.1"
                     /evalue="4.40E-23"
                     /label="ctg228_1_PCP.1"
                     /locus_tag="ctg228_1"
                     /protein_end="883"
                     /protein_start="817"
                     /score="73.0"
                     /tool="antismash"
                     /translation="EQKLVEVWSQVLRKEVIGIYDNYFTLGGDSIKAIQIISRLHQEGW
                     AAEVRDIFQSPTIAELALEIKV"
     aSDomain        2683..3606
                     /aSDomain="Epimerization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg228_1_Epimerization.1"
                     /evalue="1.40E-129"
                     /label="ctg228_1_Epimerization.1"
                     /locus_tag="ctg228_1"
                     /protein_end="1202"
                     /protein_start="894"
                     /score="424.8"
                     /tool="antismash"
                     /translation="TGDVPLSPIQAWFFAQPNPALHHFNQSVLLKSAARLNADRLRTVF
                     EMLQIHHDALRLHYQVAEVLLGYNNLKGLVVRQQNADIDYPVNFQSIDLTNESEPTTKV
                     ESYANALHESFNLGQGPLMKAILFHLPQEDQLFIVIHHLVVDSVSWRILLEDLMTAYTH
                     ATLGQAIQLPLKTDSFKNYAERLLEHAQSDAVVQEIPYWQAVQSTLVRSLPRDFDTADN
                     CIAETTQFTFALSAMDTQILLTDAHQAYHTRIDDLLLTALALALKQWHSGDKTLIVLEK
                     YGREVLDLNLSRTVGWFTSIYPFVLELP"
     CDS_motif       2698..2727
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg228_1_0005"
                     /evalue="2.50E-03"
                     /label="NRPS-E1"
                     /locus_tag="ctg228_1"
                     /protein_end="909"
                     /protein_start="899"
                     /score="11.0"
                     /tool="antismash"
                     /translation="LSPIQAWFFAQ"
     CDS_motif       3088..3153
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg228_1_0006"
                     /evalue="2.70E-11"
                     /label="NRPS-E2"
                     /locus_tag="ctg228_1"
                     /protein_end="1051"
                     /protein_start="1029"
                     /score="35.6"
                     /tool="antismash"
                     /translation="LFIVIHHLVVDSVSWRILLEDLM"
     CDS_motif       3550..3600
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg228_1_0007"
                     /evalue="2.30E-08"
                     /label="NRPS-E5"
                     /locus_tag="ctg228_1"
                     /protein_end="1200"
                     /protein_start="1183"
                     /score="26.1"
                     /tool="antismash"
                     /translation="NLSRTVGWFTSIYPFVLE"
     aSDomain        3622..4089
                     /aSDomain="TIGR01720"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg228_1_TIGR01720.1"
                     /evalue="1.50E-44"
                     /label="ctg228_1_TIGR01720.1"
                     /locus_tag="ctg228_1"
                     /protein_end="1363"
                     /protein_start="1207"
                     /score="143.2"
                     /tool="antismash"
                     /translation="LGYQIKFIKESLRKVPNFGLNYGVLKYLTPPQQKMGLSSQDNVAQ
                     LGFNYLGQLDTAEDESSIFTVDWDSVGQGMSPQMPRVHDIDILSWVVDGKLEISLTYHQ
                     QRYQLATIQRLATAYEQALRAVITHCQSREGSELTPDDFTYKGLSLTDLDNLF"
     CDS_motif       3643..3705
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg228_1_0008"
                     /evalue="8.00E-07"
                     /label="NRPS-E6"
                     /locus_tag="ctg228_1"
                     /protein_end="1235"
                     /protein_start="1214"
                     /score="21.5"
                     /tool="antismash"
                     /translation="IKESLRKVPNFGLNYGVLKYLT"
     CDS_motif       3703..3720
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg228_1_0009"
                     /evalue="7.80E+01"
                     /label="NRPS-E1"
                     /locus_tag="ctg228_1"
                     /protein_end="1240"
                     /protein_start="1234"
                     /score="-2.1"
                     /tool="antismash"
                     /translation="LTPPQQK"
     CDS             4445..4972
                     /locus_tag="ctg228_2"
                     /transl_table=11
                     /translation="MLKILNKIRKIGIITESLPTLSHHERDAKVEETGKQVKAEIVRCF
                     GGSLAIRQVDAGSCNACELEIHALSNPFYDIERFGIHFVASPRHADMLLVTGVVSRNME
                     AALMRTYEATPYPKLVIAMGECAVNGGEFGISYASCGAVHHIIPVDAVISGCPPTPLDL
                     MQGILQVIRQNS"
     CDS             complement(4946..6445)
                     /gene_functions="other (smcogs) SMCOG1272:TPR
                     repeat-containing protein (Score: 64.9; E-value: 1.2e-19)"
                     /gene_kind="other"
                     /locus_tag="ctg228_3"
                     /transl_table=11
                     /translation="MEQTDQNTQFTQAKTLYDKGLAAFQQQDFAQAEHWLQQAITLHPT
                     DNYCIQLGIVYGVQNQDEAALTWFQRAISLNPNNYAPYFNIANVLQGQRLLDKALDYYQ
                     YAFTLNPLFAPTYNHVGDILYIQEKYDRAIVYYQHSLALQPDAYETLLNLGKSCYRNGQ
                     QPQAVHYYQQALSLRPDAAEAHFGLSLSLLLLGNYTEGWQKYEYRLQLDEGGVKLPIFK
                     KPRWDGSNLAGRRLLVLCEQGLGDTLQFSRYLPLIQGGRVIFTCQTALMPLFENFVGID
                     ELLEYQEQEPKIDYDVYIPLMSLPALFHTTLETIPHHVPYLSVSPQKIAQWQPRFDHQK
                     FNIGIVWSGNPQFIDNHNRSCQLADFLPLAQISEIQLYSLQKGDAAQLQLTEFTELSII
                     NLNQELQDFADTAAVLRCLDLLISVDTSVPHLAGALGVPIWLLLKYVPDCRWLLDRNDS
                     PWYPTMRLFRQTSPKNWQPVFQQVTEALQQFKKSRILSDHL"
     CDS             complement(6515..8482)
                     /gene_functions="other (smcogs) SMCOG1061:methyl-accepting
                     chemotaxis protein (Score: 217.7; E-value: 5.1e-66)"
                     /gene_kind="other"
                     /locus_tag="ctg228_4"
                     /transl_table=11
                     /translation="MMKNFSIAKKFLILSLVAISALVLIGLYGLFNTYSTFHWVGKVYE
                     TVGKIENINQKIAYPLNELRQTSLSLVTAPSQKLREAFQQQEVKLINQLEENFTQWQQT
                     LVDQEKREFEKLTAAWQQYKTLLLYTNEQALAGYREAAFINVTGAEKQQFDVLFQQFSD
                     WMKHNVTQAEGLYSLAKQNFSSMQWVFGGAFVVFTLTVILLSLYLARGIIGSLSQAVRV
                     ANTVSKGNLTIITESNYPTDEAGQMLTAMHEMVDNLREIVMQLRHTVKSITTTTSQLIA
                     TNTKISTGARQQVSATELTFKAIAQVDDSIEQVSINAQSLLNNVENTASSIETMNQVIQ
                     SIAGNIAKLTHAVNDTFSSIEQMAGSIEHIANNTRDVGQSSKIAVQEVAEGRIAVKETI
                     TEMYEISSTMQDIVAVIERLDANNRKINGIVDIISDIAEQTNLLALNAAIEAARAGEHG
                     RGFAVVAQEVRKLAERSGSLSKEIIHLTDDVQKDTQSARQVTQLGTSKAEKGVQLATQA
                     GEVLEQIMGTIAKVNQMVTEIEKTTENQAKSSEKVVKTVDSIWQVAQEVDTATREQAVS
                     SQQMIAAVSMMSQMTRQVSEEMGGQKRGTSQVVMEVKNIASISQQNLETVSQITEIADS
                     LNEQTCELQKLTNFFNYQRS"
     CDS             9067..10593
                     /gene_functions="regulatory (smcogs) SMCOG1003:sensor
                     histidine kinase (Score: 136.6; E-value: 2.5e-41)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg228_5"
                     /transl_table=11
                     /translation="MLSGRSILPPQLFYEAVEQSHVAISITDLNANILYANPAFQRVTG
                     YNGSEIQGENESFLSDKHTPRTMYNNELWECLRQQKTWSGVLLNRHKDGSRYLAEVSIA
                     PMVDEQGDTVYYLGMHRNITEIHRLAQQVKNQKAVIESVVDSAPVVIALLDDASQVVLN
                     NQEYKKLAQDLHAREPANVFLEVIKNTLGATRWEECYAAKTHFEDQEVRLDLGGRHQPR
                     WFVCSGTWFEEHEDGADDFFQPRKRDYLLLVANEITELKRQQEEVRMNALRALLAEGEL
                     VDRMRETLEGAIHELQVPINLITAALGVLERRATDAQDKALYEALQQASNSGHRALDKL
                     RHCVPMEVNEAMVPLNLNELVRDALGVFTDRLLSEGIVVDWHPALILPTVLGQMKRLRN
                     MFKQLVSNAIDSMGENRNKNRELRIVTQHAEDTVTVTIEDTGHGIPEHLRFRVFEPFFT
                     TKKRGGSGMGLATVQEIVNSHAGSISVDPQYAEGCRFIVQFPTANQRINR"
     CDS             10612..11226
                     /locus_tag="ctg228_6"
                     /transl_table=11
                     /translation="MHEVYDRGYKKLFSNKALFRELLESFVPLEWVKELDFDHCELLDK
                     TFISKEYEKRESDVIYQVQLRGQTAYIVILIEFQSSVDKFMALRILHYISSFYMRLKDS
                     EAKIDKLPPIFPIMVYSGQAQWTAPTDIAELIEHHDLLGEFALNFRYFKIAENEISAQK
                     LFEMGNVVATLFLGEAHHDRKLLVEALSKLSRNCPIRKTDN"
     CDS             11232..11546
                     /locus_tag="ctg228_7"
                     /transl_table=11
                     /translation="MLFNFFEQLFYNNKLTEVDWQAFHRVLTDSEMNMFLENMKICDEI
                     AYQKGILAGKQEGKLEGKLEGKLEGKLEMARAMLFKGLSIALIAEVTGLSESEIEQLRH
                     "
ORIGIN
        1 tatcgcgagt taaatcaagc ggcaaaccgg attgctcatg aattattaga tacctatcaa
       61 gtgcaagcgg atgaaattat tgctgtaacg gtagaacgtt cagaacaatt agtcattgca
      121 ttgttagcgg tgctcaaaac cggtgccgtg tatttaccga tagaccctac ttatccacaa
      181 gatcggatta actacatgtt aaataacagt tgttgccgtc tcttgattgt gcaaggacag
      241 gagtcaattt catcgccatc gttacagcat attattgaat taccgaaaat ttcatcgaat
      301 aatcttgcaa atccaccgat tcgagcaact gcccgcgatc ttgccttcgt gatttacact
      361 tccggctcca ccggacagcc caagggggtg atgatagaac atcggggttt tgtgaatatg
      421 gtttatgata agattcatac ctttaaggcg actcaacgtg acaaagtgct gcaatttgct
      481 tccgcttcct ttgatgcgtc cttggatgaa acttttctcg cgctactttc tggagcaact
      541 ttagtattga tcagcaagga aacgattcaa aatacacaaa aatttgctca atatctggaa
      601 aaacaagcta tcagcatttg tttattgccg ccggtgtatc tcaacgcgct caaccatcat
      661 cccctgccta cattgcgtac gctcatgacc attggtgagc ctgctattgt ggaggacgtt
      721 cagttttacg cccaaaataa aaattacttc aatgggtatg gacctacgga aacttcaatt
      781 tgtgccacgc tgtatcaagt tgaagaaaat caatgggata atcacaacgt tcctatcgga
      841 aaacctgtgg tcaacacggc aatctatgtg cttgattctg gcttaaacct tgcgccaatt
      901 ggcatcgtag gcgaaatatg tattgctggt catggggttt cacgcggcta tttgaacaat
      961 cccagtttga cacaggaaaa atttgtcgat aatccattca aacccggtga aaagatgtat
     1021 aaaacggggg atttgggacg ttggttagcg gagggcaatt tggaattttt ggggcgcacc
     1081 gacgatcaag tcaaaatttc cggacatcgg attgagctga gtgaaattga atacgcattg
     1141 cgccaacatc cgtatattca agaagttgtg gtcgcggcga agggtgacaa ggcaactgaa
     1201 aaaaccttga gtgcctattt tacacgcaaa caaaaggtgg aattatttcc atctatcgca
     1261 gaattttatg tgtatgatga tgtggtttat cgcagtatgg caaccgatga agccagaaac
     1321 gaacgctacc gtgccgcgtt taattcattg aaaaataaga aagttgtcga gattggaccc
     1381 ggtccagaag ttattttaag ccgattgtgc ctcgaagcgg gggctgaaaa aatctatgcg
     1441 attgaattat tagaagaaac ctatcgcaaa gctcaattga cattacaacg cttaggattg
     1501 gaagatcgca ttatcctaat ccatggggat gcaactcaag tcgaactcac tgaaaaggtt
     1561 gattattgta tctcagaaat cgttggtgca attggtggct ccgaaggttc cgcaaaaatt
     1621 atcaacgaaa cccgccattt tttacacgat gggcgttgta tgattccaca gcgtagtttg
     1681 accaaaattg ccgcgtttag cttgccaacc accgattttg attatcattt ttcaccgata
     1741 gccgcgcatt atgtgaaaca gatttttgca caaaaaggct actcttttga cttgagatta
     1801 tgtgtgaaga atttcaacca caacgcactg ctttccaacg cggatgtgtt tgaagattta
     1861 gattacactc aagagattac gcttgaaacc acgcattcca ttgaattggt gatcgagaaa
     1921 gcaggtgtat tcaccggatt tttagtctgg ttgacacttt acactgacgc gagccatgtc
     1981 gttgatattc ttgaacaaca agccagttgg attccggttt atttaccgat tgatctcagt
     2041 ggcattgaag tacaacccgg cgacaaaatc ctcgcgacca ttgaccgcaa actgtgttct
     2101 aacggcttaa atccagattt cttcgtcaac ggcgagataa ttcgcaaaaa tcatgtccct
     2161 gtgccattta actacgcgtc ttatcacgat aaatcactgt ttcgtgccac gccgttttat
     2221 gcacaattgt ttgcagacgg acagattccc atgcagccgg cactcaccac agacgattta
     2281 cgaaatttct tgattgattc cctgccaaac tacatgttac cgtcatattt catggagtta
     2341 gcacaacttc cattgactcc aaatggtaag gtcgataaaa aagccctgcc aatgccagag
     2401 ataacaaccg tcacagaatc ccacaattat gctgccccgc gcacgacaat ggagcaaaaa
     2461 ctggttgaag tgtggtctca agtgttgcgt aaggaagtga ttggaattta tgacaattat
     2521 tttactttgg gcggcgattc gattaaagcc attcaaatca tatcaagact acatcaagaa
     2581 ggttgggcgg cagaagtacg agatattttc caatcaccca cgattgccga attagcgtta
     2641 gaaatcaaag tattgaagcg tgaaattgag caagatgtgg tgacaggaga tgtgccgtta
     2701 agtccaattc aagcgtggtt ttttgcccag cccaatccgg cattacatca tttcaatcaa
     2761 tccgtgttac taaaatccgc ggcgcgtttg aatgcagacc gactacgcac agtgtttgaa
     2821 atgctgcaaa ttcatcatga tgcgttgcga ttgcattacc aagtggcgga agttttattg
     2881 ggatacaaca atctcaaggg gcttgtcgtg cgacagcaaa atgccgacat cgattacccg
     2941 gtgaattttc aatcaattga tttaactaat gaatctgaac cgacgaccaa ggtggaaagt
     3001 tacgccaacg cgctgcatga aagtttcaat ctcggtcagg gcccgttgat gaaggcgata
     3061 ttattccact taccccaaga agatcaattg tttatcgtga ttcatcactt ggtcgtcgat
     3121 agcgtatcat ggcgaatttt gttggaagac ttaatgactg cttacactca cgccacattg
     3181 ggacaagcca ttcaattgcc tttaaaaaca gactctttca aaaattacgc agaaagattg
     3241 ttagaacatg cccagagtga cgcagtggtg caggaaattc catattggca agcggtgcaa
     3301 tcaaccttag tgcgtagttt accacgggat ttcgatactg cggacaattg tattgcagaa
     3361 acgacgcaat ttacgttcgc attgtcggca atggacacac aaattttatt gaccgatgcc
     3421 catcaggcgt atcacacgcg aattgacgat ttattattga ccgcgttggc attggcattg
     3481 aaacagtggc actctggcga taaaaccttg attgtgcttg aaaaatatgg acgggaagta
     3541 ttagatttga acctgagtcg cacggtcggt tggtttacga gcatctaccc gtttgtgttg
     3601 gaattgccgg aaactgaaga tttgggctat cagatcaagt ttatcaagga atcgttgcga
     3661 aaagtgccta atttcggttt aaattacggt gttctcaaat acttaacgcc accacagcag
     3721 aaaatggggc tgagttcgca agataatgtg gcacaattgg gtttcaatta cttgggacaa
     3781 ctcgacacgg cagaggatga atcttcaata tttacagtcg attgggattc tgtggggcag
     3841 ggaatgagtc cccagatgcc gcgggtacac gatattgata ttttaagttg ggttgtcgat
     3901 ggaaaattag aaatttcatt gacttatcat caacaacgct atcaactcgc cacaatacaa
     3961 cggctggcga ccgcgtatga acaggcattg cgcgctgtca ttacgcattg tcagtcgcgt
     4021 gaaggtagcg aattgactcc cgatgatttc acctacaaag ggctgagttt aaccgatttg
     4081 gataacttgt tcgattaatt atatgatttt attgaatttt tcaagtaaaa tttgatataa
     4141 attgacattt cgacattttg gagtttaaaa cggtcttttt gacaatctac cgtttttaga
     4201 ctccaaaaaa atgttggtcg tgatgtgtgc taaaatctca gcaattgcat cgaagccttg
     4261 atgaatcatt aggacattgt tcattccagt aaaatgtagc taaccatcgg ttttaaaatg
     4321 aaatttatta tccaacttta tagttttatt ttaatttcaa tcggtgggtg aaaattaaca
     4381 ttttcgatag attcatcata ttcacttcgt gttccactca ttatgactca ttcaaacact
     4441 cgttatgctc aaaattctca ataaaattcg taagataggt attatcaccg aatctctacc
     4501 cacattatcc catcatgaac gagatgccaa agttgaagaa actggtaaac aagtcaaggc
     4561 tgagatagtg cgttgttttg gtggaagttt agcgattcgc caagtggacg cgggatcgtg
     4621 caatgcgtgc gagctcgaaa ttcatgcgtt gagcaatcca ttctatgaca ttgaaagatt
     4681 tggaattcat ttcgttgctt cccctcgtca tgcggatatg ctactggtga ccggcgtggt
     4741 atctcgcaat atggaggcgg cattgatgcg tacttacgaa gcgactccct accctaagtt
     4801 agtgattgct atgggagaat gcgcggtcaa tgggggcgaa tttgggattt cctatgccag
     4861 ttgtggggcg gtgcatcata ttatcccagt cgatgcagtg atttccggct gtccaccaac
     4921 gccgctggat ttgatgcaag gaattttaca ggtgatccga caaaattctt gattttttaa
     4981 actgttgcaa cgcttcggtg acttgttgaa atactggttg ccaatttttt ggagatgttt
     5041 gacgaaataa ccgcatcgtc ggataccacg gactgtcatt tctatccaaa agccaacgac
     5101 aatcaggaac atacttcaat aacagccaga ttggaacacc caaagctccc gccaaatgtg
     5161 gcactgaggt atcaacggaa atcaataaat ctaaacaacg caatactgcg gcagtatcgg
     5221 caaaatcttg taattcttga tttaagttga tgatagataa ttcggtaaat tcagtgagtt
     5281 gcagttgtgc cgcgtcacct ttttgtaaac tatagagttg aatttcagaa atctgtgcca
     5341 atggcaaaaa atcggctaat tgacaggagc ggttatgatt gtcgataaat tgtggattgc
     5401 ctgaccacac gataccaatg ttaaattttt ggtgatcaaa acgcggttgc cactgtgcaa
     5461 ttttctgtgg tgaaacagag agatagggta catgatgggg aatcgtttct aatgtcgtgt
     5521 ggaataacgc aggcaagctc atcaggggaa tataaacatc ataatctatc ttgggttctt
     5581 gttcttgata ttcaagcagt tcatcaattc ccacgaaatt ttcaaacaac ggcatcaatg
     5641 cagtttggca ggtgaaaatc acgcgaccac cttgaattaa cggcaaataa cgcgaaaatt
     5701 gtaacgtgtc tcccaatcct tgttcacata ataccaataa acgccgtccg gctaaattgc
     5761 tgccatccca acgaggtttt ttgaaaatag ggagttttac cccgccttcg tctaattgca
     5821 gtcgatattc gtatttttgc caaccttccg tgtaatttcc taacaataac aacgataaag
     5881 ataatccaaa atgagcttct gcggcatcgg gtcgcagcga aagggcttgt tgataataat
     5941 gaactgcttg gggttgttga ccattacgat agcaagattt tcccaaattt aacaacgtct
     6001 catacgcgtc cggctgcaac gcaagcgaat gttgataata aacaatggct cggtcatatt
     6061 tttcttgaat atacaaaatg tcacccacat gattgtacgt cggggcaaag aggggattga
     6121 gcgtaaaagc atattgataa taatcaagag ctttgtcgag taaccgctgc ccctgtaaca
     6181 cattggcgat gttaaaatac ggagcgtaat tattcggatt caatgagata gcgcgctgaa
     6241 accatgtcaa tgctgcttca tcttggtttt gcaccccata cacaatgccc aactgaatgc
     6301 aatagttatc cgtcggatgg agcgtaatcg cttgttgcaa ccagtgttct gcttgagcaa
     6361 aatcttgttg ttgaaacgcg gctaacccct tgtcatataa agtttttgct tgggtaaatt
     6421 gcgtattttg gtcagtttgt tccataaaaa gaggatcaga ggataaaaag ttatttcaaa
     6481 taaaaaacta ccgcatcgtc atctcgaaaa atactcaaga acgttggtaa ttgaaaaagt
     6541 tcgtcagttt ttgtaattca caagtttgtt cgtttaaact gtctgcaatt tcagtaattt
     6601 ggctcactgt ttcaagattt tgttgcgaaa tcgaagcgat atttttcact tccatcacca
     6661 cttggctcgt cccgcgtttt tgcccgccca tttcctccga aacctgccgc gtcatctgac
     6721 tcatcatgct caccgccgca atcatctgtt gactgctcac cgcttgttcc ctagttgctg
     6781 tgtcaacttc ttgggcaacc tgccaaatgc tgtcaaccgt tttgaccact ttttcggacg
     6841 atttcgcttg attttcagtc gttttctcga tttctgtcac catctgattg actttggcaa
     6901 ttgttcccat aatttgctct aatacttcac ccgcttgggt cgccaattgc acgccctttt
     6961 ccgctttcga cgtacctaat tgcgttacct gtctggcact ctgggtatct ttttgcacgt
     7021 catcagttaa atggatgatt tctttcgaca aactgccaga acgttcagcc aatttacgca
     7081 cttcttgggc aacaacggca aagccccgtc catgttcccc tgcgcgtgcc gcttcaattg
     7141 cagcattgag ggctaataaa ttagtttgct cggcaatatc gctgataata tcgacgatac
     7201 cattgatttt acgattattt gcgtccaacc gctcaatcac tgcaacaatg tcttgcatcg
     7261 tgctcgaaat ttcatacatc tcggtaatgg tttctttcac cgcaatccgc ccttccgcca
     7321 cttcttgcac cgcgattttg gaagattgcc caacatcacg agtattattc gcaatatgtt
     7381 ctatcgatcc cgccatctgt tcgatgctgc taaatgtgtc attgaccgcg tgtgtgagtt
     7441 tggcgatatt gcctgcaatt gattgaatta cttggttcat cgtttctatt gaactggcgg
     7501 tgttttctac attgttgagc agagattgag catttatgga aacttgttca attgaatcat
     7561 caacttgagc gattgctttg aaagtcaatt cggttgcaga tacctgttgt cgcgctcctg
     7621 tggaaatttt cgtattggtg gcaatgagtt ggctggtggt ggtggtaatg gatttcacgg
     7681 tatggcgtaa ctgcattaca atttcacgca aattatcaac catttcgtgc atcgcggtga
     7741 gcatttgccc ggcttcatcc gtaggataat ttgattcggt aattatcgtt aaatttcctt
     7801 tgcttaccgt atttgccact cgcaccgctt gactcaatga accaataatg ccacgcgcca
     7861 agtacaaact aagcaagatg acggtcaagg taaataccac aaatgccccg ccaaagaccc
     7921 attgcatgga tgaaaaattt tgcttcgcca aggaatataa accttctgct tgagtcacat
     7981 tgtgtttcat ccaatcagaa aattgttgaa ataaaacatc gaattgctgt ttttctgccc
     8041 cagtcacatt gataaacgcg gcttctcgat acccggctaa cgcttgctca ttggtataaa
     8101 gcagtaatgt tttatattgc tgccatgcgg cggttaattt ctcaaattcc cgtttttctt
     8161 gatcaacgag ggtttgttgc cattgggtga aattttcttc taactgattg attaatttaa
     8221 cttcttgttg ttgaaatgct tcacgcaatt tttggctggg agcggtgact aaagaaagcg
     8281 aggtttgacg caactcgttc aatggataag caattttttg attaatgttc tcaatcttgc
     8341 cgacggtttc gtaaacttta ccaacccagt gaaacgttga ataggtgttg aacagtccat
     8401 ataatccaat caatacgagg gcggaaatgg caaccaatga cagaatcagg aattttttgg
     8461 caatgctgaa atttttcatc atgttgttca ccatgaaatt gttgattaca aatggcaagt
     8521 aaaatcaatt gattatgttt tgaaattcag ataaactcaa tgtgacggct ttctaaaatc
     8581 atatcacgat aggtaatcag tatagcaaaa aaatggattc ttcaaaaaaa ttggcgacgg
     8641 tattgctagc aaaaatttaa ttttaacgta tttaaattta tcatgtttcc aaaacttggg
     8701 tttaattcca tttaaacatc attgacttca ttgttcagcg gcaaacgaaa agatattgta
     8761 gaatatgcga tgaaggattc ttgttgacag cggattaagc aaggataatt tgacgtttga
     8821 aatttttatg cgtgacgctg cttcaatctc acgttccatg aatttcctaa atctaatatt
     8881 ttatgcgaaa tcagagagtt atcaatattg atcttggttc gctaaccgat tcaaatctaa
     8941 agatgaaatc gctcaattat tcacattggt atatcacatt ttcttaaaaa ataatattat
     9001 aatcaattaa ttattcattt atctaaaact gctgacacaa ccaaatcaac aatttacggg
     9061 gatactatgt tatcaggtcg cagtatttta ccgccacaac tgttttatga agcggttgaa
     9121 caatcccatg ttgcgatatc gatcactgat ttaaacgcca atattcttta tgcaaatcct
     9181 gcgtttcagc gggtcactgg ttacaatggc agtgaaattc agggcgaaaa tgagtcgttt
     9241 ttgtcggaca agcatacccc tcgcaccatg tataataatg agttgtggga atgtttgcgg
     9301 caacaaaaaa cgtggtctgg cgtattgtta aatcggcata aggatgggtc gcgctatttg
     9361 gcggaagtca gtattgcacc gatggttgat gaacagggtg acacggttta ttatttggga
     9421 atgcaccgta atatcacgga gatacaccgc ctcgcgcaac aggtcaaaaa tcaaaaagcg
     9481 gtgattgaat ccgttgtcga ttctgcgccg gtggtcattg ctttgttaga cgatgccagc
     9541 caagttgtgc tgaataatca agaatataaa aaattagcgc aggatttaca tgctcgtgag
     9601 cctgccaatg tctttttaga agtgattaaa aatacgttgg gcgcaacccg ttgggaagaa
     9661 tgttatgccg cgaaaaccca ctttgaagat caagaagtgc ggctggattt gggcgggcgg
     9721 catcaaccgc gttggtttgt ctgttcagga acttggtttg aagaacatga agatggtgca
     9781 gacgattttt tccaaccccg taaacgcgat tatttgctcc tcgttgccaa tgaaatcacc
     9841 gagttaaaac ggcaacaaga agaagtgcga atgaatgcgt tgcgagcgtt gttggctgaa
     9901 ggggaattgg ttgatagaat gcgtgaaaca ttggaagggg cgattcatga attgcaagtg
     9961 cctatcaatt taatcaccgc agcacttggg gtattggaac gtcgagccac cgatgcacag
    10021 gataaagccc tgtatgaagc cctacaacaa gcctccaatt cgggacatcg ggcgttagat
    10081 aaattgcgtc attgtgtgcc gatggaagtg aatgaggcaa tggtaccgtt gaatttaaac
    10141 gaattagtga gagatgcact gggcgtattt acagatcgtt tactcagcga aggaattgtg
    10201 gtggattggc atccggcgtt gatattgccg accgtgttgg ggcaaatgaa gcgattacgc
    10261 aacatgttca aacaattggt gagcaatgcc attgattcga tgggagaaaa tcgcaataaa
    10321 aatagagaat tacgcattgt cacgcaacat gccgaagata cggtgacagt gacgattgaa
    10381 gacacagggc acggtattcc tgaacatttg cgatttcgag tgtttgaacc gtttttcacc
    10441 accaagaaac gcgggggtag cggtatgggc ttggcaacgg tgcaagaaat tgtcaattct
    10501 cacgcaggtt cgatcagtgt tgatccccaa tacgctgaag gatgtcgatt tattgtacag
    10561 tttcccacag caaatcaacg aattaatcgc taatgggctt actttaacaa aatgcacgaa
    10621 gtttacgacc gcggctacaa aaagttattt tctaacaaag cattatttcg tgaattgctc
    10681 gaatcgtttg tgccgctgga atgggtgaaa gaattagatt ttgaccactg cgaattgctg
    10741 gataaaacct ttatttccaa agaatatgaa aaacgggaaa gtgatgttat ctaccaagtt
    10801 caattgcgtg gtcaaaccgc gtacattgtg attttgatag aatttcaatc gagtgttgac
    10861 aaattcatgg cattacggat tttgcactac atttctagtt tttacatgcg tttgaaggat
    10921 tcggaagcga aaatagataa attaccgccg atatttccga tcatggttta cagtggtcaa
    10981 gcgcaatgga cggcaccgac agatatagct gaattaattg aacatcatga tttacttggt
    11041 gaattcgccc tcaacttccg ctatttcaaa attgcagaaa atgaaatctc agcacaaaaa
    11101 ttatttgaga tgggcaatgt ggtcgcaaca ctatttttag gtgaagcaca tcacgacaga
    11161 aagttattag tcgaagccct atcgaaactg tccagaaatt gcccaatccg gaagaccgac
    11221 aactgatttc gatgctgttt aacttctttg agcaactgtt ttacaacaac aaattgacag
    11281 aagtggattg gcaagccttt caccgggtac tcacggattc ggagatgaat atgttcttag
    11341 aaaacatgaa aatatgtgac gaaatcgctt atcagaaggg aatcctcgca ggtaagcagg
    11401 aaggtaaact tgaaggaaaa ctcgaaggaa aacttgaagg aaagttagaa atggcaaggg
    11461 caatgctgtt taagggtctg agtatcgcgt tgattgcaga agtcactgga ctttctgaat
    11521 cagaaattga gcaattgcga cattaaaaat gcacgaagtt tacgaccgcg gctacaaaaa
    11581 gttattttct aacaaagtta ggagttacgc agttgaatcg ttactcaatt gattttatta
    11641 aaatatcaac aaatcgatca aaatactaac tttttgaata aattgaaaat tagatttgaa
    11701 ct
//
