LOCUS       c00012_3300000..       22524 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300000236.a:TB_FS08_3DRAFT_1000054.
ACCESSION   c00012_3300000..
VERSION     c00012_3300000..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 06:03:44
            Original ID  :: 3300000236.a:TB_FS08_3DRAFT_1000054
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 22524
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..22524
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1:2524](+)"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2..2524
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
     cand_cluster    1..22524
                     /SMILES="NCC(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /detection_rules="(HMGL-like and AMP-binding)"
                     /kind="chemical_hybrid"
                     /product="NRPS-like"
                     /product="betalactone"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     region          1..22524
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS-like"
                     /product="betalactone"
                     /region_number="1"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX))"
                     /rules="(HMGL-like and AMP-binding)"
                     /tool="antismash"
     protocluster    1..19154
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1:9154]"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      2..9154
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="2"
     aSDomain        2..1129
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg12_1_AMP-binding.1"
                     /evalue="1.10E-109"
                     /label="ctg12_1_AMP-binding.1"
                     /locus_tag="ctg12_1"
                     /protein_end="376"
                     /protein_start="0"
                     /score="358.5"
                     /specificity="consensus: gly"
                     /tool="antismash"
                     /translation="SLTYVQLNEKANQLAHFLKNQYHVQSDTLIGICIERSLEMVIGLL
                     GILKAGGAYVPLDPNYPQERLAWMLEDSRVSVLLTQTSLQNTLPEHQADILCLDNWERF
                     AQQSTKNLELALNSDSLAYVLFTSGSTGRPKGVMIEHQALHNFLHDMQLRLQSKLNSYL
                     LAVTTLSFDIAGLELYLPLLTGMGIVLTDRETASDGEKLQVLLQQYDICLMQATPATWK
                     LLLDNNWQQNRPLTILCGGEALPENLGQALLQQSEQLWNVYGPTETTIWSSAHNATQSP
                     EQPSLIGKPLSNTRIHIVDTQNHPVPIGIAGELCIAGDGLARGYLNRPDLTAEKFVELE
                     LFGKTERVYKTGDLARWLPDGNLDYLGRIDHQVKLRG"
     aSModule        2..2467
                     /complete
                     /domains="nrpspksdomains_ctg12_1_AMP-binding.1"
                     /domains="nrpspksdomains_ctg12_1_PCP.1"
                     /domains="nrpspksdomains_ctg12_1_Thioesterase.1"
                     /final_module
                     /locus_tags="ctg12_1"
                     /monomer_pairings="gly -> gly"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS             2..2524
                     /NRPS_PKS="Domain: AMP-binding (0-376). E-value: 1.1e-109.
                     Score: 358.5. Matches aSDomain:
                     nrpspksdomains_ctg12_1_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (482-551). E-value: 6.3e-26. Score:
                     82.2. Matches aSDomain: nrpspksdomains_ctg12_1_PCP.1"
                     /NRPS_PKS="Domain: Thioesterase (568-822). E-value:
                     3.9e-33. Score: 107.5. Matches aSDomain:
                     nrpspksdomains_ctg12_1_Thioesterase.1"
                     /NRPS_PKS="type: NRPS-like protein"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     313.4; E-value: 3.7e-95)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg12_1"
                     /sec_met_domain="AMP-binding (E-value: 8.1e-116, bitscore:
                     378.3, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 4e-16, bitscore:
                     50.8, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="SLTYVQLNEKANQLAHFLKNQYHVQSDTLIGICIERSLEMVIGLL
                     GILKAGGAYVPLDPNYPQERLAWMLEDSRVSVLLTQTSLQNTLPEHQADILCLDNWERF
                     AQQSTKNLELALNSDSLAYVLFTSGSTGRPKGVMIEHQALHNFLHDMQLRLQSKLNSYL
                     LAVTTLSFDIAGLELYLPLLTGMGIVLTDRETASDGEKLQVLLQQYDICLMQATPATWK
                     LLLDNNWQQNRPLTILCGGEALPENLGQALLQQSEQLWNVYGPTETTIWSSAHNATQSP
                     EQPSLIGKPLSNTRIHIVDTQNHPVPIGIAGELCIAGDGLARGYLNRPDLTAEKFVELE
                     LFGKTERVYKTGDLARWLPDGNLDYLGRIDHQVKLRGFRIELGEIEAILTQQESIKDAI
                     VILHEKDGNKSLAAYLVLADKNADISDLREVLKVKLPDYMVPTYFTILDKLPLTPNGKI
                     DRKALPEPEKSHITSNQETPRNQAELQLIQTWQKVLNIQKIGIRDNFFELGGHSLLAVQ
                     LMSHIQQHWQQKLPLAVLFSSPTIAQLAQHLQQNNTQHSCLVPIQIQGSQPPLYCLPGA
                     GGHVLYLHALACHLGIDQPLYGLETPGLHGECPMPDSVEQHAALLLQAIRKQQPNGPYR
                     FAGHSAGGRVALALAHQLEKQGEKIQCLIILDTTAPQINPEPTAELTEVEALWSVVKIV
                     EELKNTQIDLTEAEIAAESDSYKRYEQVMEHVQIAGMFAPQTPVEELKHLVAIYQTMIR
                     NHAYYRPNYQINCPIILVKAKEIPNETERPNSLDWGWQLYSTQTVQIIETSGGHITMLT
                     QPYVAELASLLTQAMANTMNKNTQENLL"
     CDS_motif       134..175
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_1_0001"
                     /evalue="2.30E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg12_1"
                     /protein_end="58"
                     /protein_start="44"
                     /score="20.5"
                     /tool="antismash"
                     /translation="LGILKAGGAYVPLDP"
     CDS_motif       365..424
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_1_0002"
                     /evalue="1.90E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg12_1"
                     /protein_end="141"
                     /protein_start="121"
                     /score="35.5"
                     /tool="antismash"
                     /translation="AYVLFTSGSTGRPKGVMIEHQ"
     CDS_motif       920..1009
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_1_0003"
                     /evalue="1.60E-18"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg12_1"
                     /protein_end="336"
                     /protein_start="306"
                     /score="58.7"
                     /tool="antismash"
                     /translation="PIGIAGELCIAGDGLARGYLNRPDLTAEKFV"
     CDS_motif       1094..1159
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_1_0004"
                     /evalue="1.20E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg12_1"
                     /protein_end="386"
                     /protein_start="364"
                     /score="39.7"
                     /tool="antismash"
                     /translation="YLGRIDHQVKLRGFRIELGEIEA"
     aSDomain        1448..1654
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg12_1_PCP.1"
                     /evalue="6.30E-26"
                     /label="ctg12_1_PCP.1"
                     /locus_tag="ctg12_1"
                     /protein_end="551"
                     /protein_start="482"
                     /score="82.2"
                     /tool="antismash"
                     /translation="ELQLIQTWQKVLNIQKIGIRDNFFELGGHSLLAVQLMSHIQQHWQ
                     QKLPLAVLFSSPTIAQLAQHLQQNN"
     aSDomain        1706..2467
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg12_1_Thioesterase.1"
                     /evalue="3.90E-33"
                     /label="ctg12_1_Thioesterase.1"
                     /locus_tag="ctg12_1"
                     /protein_end="822"
                     /protein_start="568"
                     /score="107.5"
                     /tool="antismash"
                     /translation="PLYCLPGAGGHVLYLHALACHLGIDQPLYGLETPGLHGECPMPDS
                     VEQHAALLLQAIRKQQPNGPYRFAGHSAGGRVALALAHQLEKQGEKIQCLIILDTTAPQ
                     INPEPTAELTEVEALWSVVKIVEELKNTQIDLTEAEIAAESDSYKRYEQVMEHVQIAGM
                     FAPQTPVEELKHLVAIYQTMIRNHAYYRPNYQINCPIILVKAKEIPNETERPNSLDWGW
                     QLYSTQTVQIIETSGGHITMLTQPYVAELASLL"
     CDS_motif       1886..1960
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_1_0005"
                     /evalue="1.40E-11"
                     /label="NRPS-te1"
                     /locus_tag="ctg12_1"
                     /protein_end="653"
                     /protein_start="628"
                     /score="36.7"
                     /tool="antismash"
                     /translation="QPNGPYRFAGHSAGGRVALALAHQLE"
     CDS             2521..4662
                     /gene_functions="other (smcogs) SMCOG1037:heavy metal
                     translocating P-type ATPase (Score: 409.9; E-value:
                     3.5e-124)"
                     /gene_kind="other"
                     /locus_tag="ctg12_2"
                     /transl_table=11
                     /translation="MIIEIILIGGAFGLWKIQKSTKELTPQNTINISEVSPAKERKRHL
                     LHDIRDALRAEGRQQLQLDIDPKQRALLEAQERERKRDMQLSLGAMGLALLGSFSPTFT
                     LIGAAAVLYLSKETFKLIHKDFKRGHYLSVYLIGLIVTLGMIVTGNLLLAAFTGVIGGF
                     FAGIINRLESDSQQQLIRVFSGHPQQVWLLRDGVEIQIDFHQLQVGDLVIVNAGEVIPV
                     DGSIQSGEGRVDQHLLTGESEAVERTIGESVYASTLLLSGRLVIEVSQAGDATMAAKIG
                     EVLNQTQNYKETLMTRGRVVADRFLPVTVGASALTLPILGPNAAIAVLWSNLGGIMAPA
                     GSLTVLSYLQIMSRHQILVKDGRVFESLKQVDTIIFDKTGTLTLEQPIVSKIHTFDAFT
                     EVEVLRYAAAAEYRQPHPIAKAIITAAQAQQIDIPQLDEAAYEVGYGIKVVVETQIIRV
                     GSVRFIQREGITMPPELDLIQQQADTESHSLIYVAVDHKLAGVLEMQPSIRPEIEEIIR
                     FLKQRKIQLYIISGDHEIPTRKMAETLGIDHYFAEVLPENKADHVNQLKAQGRFVCFIG
                     DGINDAIALKSAQVSISLKGASTAATDTAQIIFVDGTLKHLTSLFQFVDEFEQTMDRNY
                     LISVVPGVVIIGGVYLLSFGIATSMALFYLSCFAGLGNTLLPLVKHQNNEIPELSKSES
                     IDLNKKSLAISDSTDQDLS"
     CDS             5011..5550
                     /locus_tag="ctg12_3"
                     /transl_table=11
                     /translation="MKIRKLTVKNYKMFDDLELDFTDSNGKALDLIVLTGVNGSGKTSI
                     LSLLRKLFSKHSNRFRSKVPLIDFEEESSGIICNEIVVETELTLDQVSSLANLISEFQQ
                     KVTSKQQLLLDPSVLSQLETVKQKLSSKKVQPGGQIWSPMVYGLKLCTSASGTMYPSVD
                     NSGLFPFSATTQKICY"
     CDS             5967..6332
                     /locus_tag="ctg12_4"
                     /transl_table=11
                     /translation="LSFEVEYTDEFGQWWDHLNEGEQESIDAIVDLLIEFGPQLKYPYS
                     SQIQGSRHSRLRELRIQHKGQPYRILYALDPRRIAILLIGGNKAGNDDWYKEFIPIAEK
                     LYDEHLKTLTEENDYDD"
     CDS             6322..6486
                     /locus_tag="ctg12_5"
                     /transl_table=11
                     /translation="MMTKPYQLLREKMSPESRKRAQQLAQQLREEMQLSKTTSGGTTEA
                     GKFLQRRDE"
     CDS             complement(6680..6895)
                     /locus_tag="ctg12_6"
                     /transl_table=11
                     /translation="LLASNSNFSHQQVDVIQFHFKIDKISEIVNIDFFKHARVLFARLL
                     VGLIHYEQIAKMMGVKQTFCQGGDVD"
     CDS             6918..7253
                     /locus_tag="ctg12_7"
                     /transl_table=11
                     /translation="LGRGSGEQYVREQFAKFITAHRRQVKCENVILVVVTDADEKDEHA
                     YEDRLNTLTNTLTEPLSKAEKIVVLIPAKNIETWFRTAESMLKTFAPTYHQMLLLPCKR
                     HVWKWKE"
     CDS             7610..9154
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271:2-isopropylmalate synthase (Score: 445.1;
                     E-value: 5.3e-135)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg12_8"
                     /sec_met_domain="HMGL-like (E-value: 2.5e-101, bitscore:
                     330.0, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDKLIIFDTTLRDGEQSPGASMTKEEKVRIAKALEKLRVDVIEA
                     GFPIASVGDFEAVQAVANTVKGSVVCGLARALDKDIERAAEALKGAAQFRIHTFLATSP
                     IHMEKKLQMAPDQVLAQAVHAVKKARRYTDDVEFSPEDAGRSEIDFLCRVIEAVIDAGA
                     RTVNIPDTVGYKLPDRFGQLMATLLERIPNSDQAIFSVHCHNDLGLAVANSLSAVMNGA
                     RQVECTINGLGERAGNAALEEVVMAIRTRKDIFPCHTDVDTTQILTCSRLVSNITGFPV
                     QPNKAIVGANAFAHESGIHQDGILKHRQTYEIMKAEDVGWHANRMVLGKHSGRNAFRDR
                     LKSLNIELNSEELVNAAFGRFKELADKKHEIYDEDLQALITDTLTSEHEEVKLVSLKVC
                     SETGETPHAQITLNINGVEQSVGAKGSGPVDATFKAIEALINSQVTLLVYSVNNVTNGT
                     DSQGEVGVRLEKEGRVVNGQGADTDIVIASAKAYLNALNKLLTVTHRQHPQVVQQV"
     CDS             9159..10100
                     /locus_tag="ctg12_9"
                     /transl_table=11
                     /translation="MTYSQDLTSRHAQYLRAMGIPIWVRRESALFLLPVAETQVPMEHD
                     GEEGPVHAIAGNPLPTADSDTFNIPPHSAVLEEEFPAIDSQTACPPTAKPTVPLPTQLV
                     PMTVSSSSSSSPLLSTNFTLSPADAALAWQDLQQRVAHCTACELCQGRTQTVFGTGNIN
                     ADYLFVGEGPGEEEDAQGLPFVGPAGRLLNAMLYAINLQREQVYIANVVKCRPPQNRNP
                     KEEEMKQCAPFLQQQIQLIQPKLIVALGAVAAQHLLAKNTPIGQLRQQQLYYQNIPLIA
                     TYHPAYLLRRPSEKRRSWQDLQFIHSTFQQLP"
     CDS             10100..10561
                     /locus_tag="ctg12_10"
                     /transl_table=11
                     /translation="MDSSPNLQLRTMQFTDLTAILEIEKVTQISPWSEQIFADCLRVGY
                     RAWVLVLDEQVIGYGLLSVGAAEAHVLNLCIHPYYQGIGYGTCLLQHLLDIAYQEAVKT
                     VFLEVRMSNQIALHLYLKMGFNQIGIRKNYYLDGQHGKEHGLILAKELL"
     CDS             10610..11503
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1081:cysteine synthase (Score: 318.5; E-value:
                     6.3e-97)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg12_11"
                     /transl_table=11
                     /translation="MKYPTIEQCVGNTPLIRLQRLPGNSSNVILAKLEGHNPAGSVKDR
                     PALSMIQQAEMRGEIQPGDHLIEATSGNTGIALAMVAAMKGYRLSLIMPENMSVERRML
                     MKAFGAQLVLVSKEGSMEAARDLALQMEREGQGKILNQFDNPDNPLAHYQNTGPEIWRD
                     TQGRVTHFVSAMGTTGTIMGVSRYLKQVNPAVRIVGVQPAEGASIPGIRRWTPEYLPKI
                     FDARQVDQMIDIDQAAAESTTRALAVQEGIFAGISSGGAVAAALQLAQQLENAVIVVII
                     CDRGDRYLSTGVFPAD"
     CDS             11633..12337
                     /locus_tag="ctg12_12"
                     /transl_table=11
                     /translation="MKKLALLGCFIFSMAPGVHAELMWGVNANGEVFRWIGIDWQRIEG
                     QLKQVSVATDGTVWGVNAKDEVWAYENSNNNWIQIPGSAKQVDVGNKDHIWSVDAKNDV
                     FRWTGNGWQQLAGKFSQISVGADGTVWGVNPQNEIWAYDANQGWVQIPGVLKQVDVADA
                     NNIWGTSANDHVYRWGGPQGWQRVEGSAKQVCVGVKGTVWSIDAQNLVFRWTGQAWQQV
                     PGTLVQLDCADY"
     CDS             12564..13310
                     /NRPS_PKS="Domain: oMT (62-168). E-value: 4.1e-07. Score:
                     20.0. Matches aSDomain: nrpspksdomains_ctg12_13_oMT.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089:methyltransferase (Score: 97.5; E-value:
                     1.4e-29)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg12_13"
                     /transl_table=11
                     /translation="MTSDKKTTHFGFTQVPIHEKVQRVTQVFASVAPRYDLMNDLMSLG
                     IHRCWKQFTLSLAQARPGEIVLDLAGGTGDLALKLAEKVAPTGQVVLADINASMLQVGR
                     ERLFNQGILVHYAQVNAEQLPFADASFDLITLAFGLRNVTDKEAALHSLFRVLKPGGRL
                     LILEFSELKIKPLKPLYDWYSFNILPKLGQLIAKDAHSYRYLAESIRMHPNQAQLLSLL
                     EQAGFERCDCHNLSGGIVAVHRGFKL"
     aSDomain        12750..13067
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg12_13_oMT.1"
                     /domain_subtype="oMT"
                     /evalue="4.10E-07"
                     /label="ctg12_13_oMT.1"
                     /locus_tag="ctg12_13"
                     /protein_end="168"
                     /protein_start="62"
                     /score="20.0"
                     /tool="antismash"
                     /translation="GEIVLDLAGGTGDLALKLAEKVAPTGQVVLADINASMLQVGRERL
                     FNQGILVHYAQVNAEQLPFADASFDLITLAFGLRNVTDKEAALHSLFRVLKPGGRLLIL
                     EFS"
     aSModule        12750..13067
                     /domains="nrpspksdomains_ctg12_13_oMT.1"
                     /incomplete
                     /locus_tags="ctg12_13"
                     /tool="antismash"
                     /type="unknown"
     CDS             13307..13765
                     /locus_tag="ctg12_14"
                     /transl_table=11
                     /translation="VTSITYAGFWRRLAALFIDSSLLGTLFLILNYGLDYFSIEKIEQS
                     PWQLFLVNDLLAALIIILYWIRCAATPGKLLFNCEIVQVTTYTAITPLQALLRYLGYFI
                     SAIPLGLGFLWILRDTRKQGWHDKMARTVVILRDESQIPLSQLMKEAQ"
     CDS             13762..14349
                     /locus_tag="ctg12_15"
                     /transl_table=11
                     /translation="MKLLTPFEKILNQSLQWDPVSLAALEPLVGKIIQVELQGLNMTIS
                     IFPDQQGVILLTDYEGPADVRVSAPPFTLLRQLLQSEQPLAQQKMLNIEGEVHTLQRFV
                     HILKHLEIDWEEQCSRFLGDWPAHTLSRWHHQGQQYAQHQFSTLQRNWVEYLQEEVHYL
                     PGQAEMQDFLNEVAILRDDVERLSQQIQRLMA"
     CDS             14353..16026
                     /locus_tag="ctg12_16"
                     /transl_table=11
                     /translation="MLHLPIRQITRLFGIYQVIVRYGLDELILSTKLFGPLHLLGYLTP
                     GYWLRPKHLSRGMRIRLALEELGPIFVKFGQILSTRRDLLPDDVAVELARLQDRVPPFD
                     GQLARQILERTYGHSLEEVFSEFNEQPLAAASIAQVHAARLHNGREVVIKIVRPGIKPR
                     IRKDIELLYLFADIANRYWSEGRRLRPREVVAEFEKNLYNELDLMQEAANATQLRRNFN
                     QLDLLYIPEVEWNYTHPNCLVMERIHGVPISDIATLRQQGTNFKYLAESGVEIFFTQVF
                     RDNFFHADMHPGNIFVDVSQPGRPHYIAVDFGIMGTLSQQDQHYLAANFLAFFRRDYHR
                     VAELHVSSGWVPPNTRVEEFEGAIRSVCEPIFDRPLKEISFGLVLLRLFQTARRFNMEV
                     QPQLVLLQKTLLNIEGLGRQLYPDLDLWKTAKPYLERWMDERVGFRAFFRGIRSNLPLW
                     AEKLPDLPLLVHESLVQQQTQSERLKQLHQGLVELKGEIHHQQKRLQWVVIGSSLLFSA
                     SLILSLQAWKLWNMPLLGIVLGGAGCFLLLLALSTAKNVD"
     CDS             16057..16536
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1163:rhodanese domain-containing protein (Score: 56.5;
                     E-value: 4.1e-17)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg12_17"
                     /transl_table=11
                     /translation="MKRYQDLITEGLQVVQEVFPWDVQPWLEQVPGPILLDVRENYEFA
                     QLHIPNSLNVPRGILEQACEYGFEETVPELVKARDRKVVVICRSGNRSVLAALTLSIMG
                     YQQVWSLKTGIKGWNDFELPLRNGQGELIDVDSADNLLISKVRADQLAPKLKAHG"
     CDS             complement(16597..17022)
                     /locus_tag="ctg12_18"
                     /transl_table=11
                     /translation="MNKTLIGCATALSLLIMPFAQAATICDVKSNLNEARASLVALLDS
                     TDKTQHEALKTAINTASTAVETAIADLLKEKAGDSQLTKLSEVWTEFKTTRETEIIPAI
                     DSGNVAKAKELATTVQAERVKSMATLVTELGGDKCTD"
     CDS             complement(17534..18856)
                     /locus_tag="ctg12_19"
                     /transl_table=11
                     /translation="MKHSLWAVLLLIYYSNVHSFCGFYVAKADTQLFNKASQVVIVRQD
                     DKTVLTMANDFKGDPQEFAIVIPVPTFIEEGQIHIGDKQIINHLDNYTAPRLVEYFDDD
                     PCRVYLREAGPAMSAAPKSESSDMIRSKKNSHGVTIEAEYTIGEYDILILSAQQSDGLE
                     QWLIENDYKIPKKANQVLDSYIRQNVRFFVAKVNLTEHSKLGFSYLRPIQVAYESPKFI
                     LPIRLGTLNADGDQELFIYTLTQKGRVETTNYRNVKLPSNMELPLFIKKEFPDFYRALF
                     EEQVRKQSMRAVFLEYAWDMNWCDPCAADPLSVEELQELGVFWLRDRRPDNWAELDVFV
                     TRLHLRYNADTFPEDLIFQETSDRENFQGRYIVRHPWEGKETCDEAKQYRQQLGVRYEG
                     EARRLADLTGWDIQKIRQKMKIPEEGTPDSKTWWQRLWHRN"
     CDS             complement(18858..19673)
                     /locus_tag="ctg12_20"
                     /transl_table=11
                     /translation="MKPLFAHLHYYDPRVYQISILSTLLIYGLFFLDFDVNPWAIILIP
                     STAILTQYAYHRYLSLPIFDAKSPLISALSLCLLLRTNSITLLLLAPIITISSKFLFRW
                     REKHLFNPTNFGLVTLLLLTEQIWVSPGQWGNGTLLALLFAGLGSWVIYQANRADITLA
                     FLIFYAIILFGRASWLGDPLTIPLHQLQSGALLLFAFFMLSDPKTTPDSRAGRLLFALL
                     VALGAAFVQFWLYRTNGLLWSLAFFSLLTPIIDRLLPNQPYQWPIHKEK"
     CDS             complement(19754..20461)
                     /locus_tag="ctg12_21"
                     /transl_table=11
                     /translation="MFKFISLLLGLMLGSLSVQAVELDTVVIHSNTSAFAAGQLLDSAK
                     ALDLSKNAEITVVFPTGGVQTVQGPYRGYLTDPRSKQTPDTQLVTTLSTFIQSNPLLRG
                     QLPPPETLWMVDVSANDRHYCLISSNEVTLLRSENQSQTADSLLIKNKRTEEFAENMWP
                     AHQETLNWPSGLPIVYGDTYTVELKNRQSGAKFKKLILYQLPSNLPTSSHKVVWMVGRG
                     CTPQASRLLASLK"
     CDS             20610..21497
                     /locus_tag="ctg12_22"
                     /transl_table=11
                     /translation="MDSFLTTVSTLPISLTSWQRSPFVIGPPITQPCQFFGRDYILKRV
                     FDVWKHLPLQHIAIVGSKRSGKTSLLHYLRRIIDTPKEELRPDQRNDWLAPGYQWVFID
                     FQDPRMCHQEGVLRHILNELDMPVPAPCDLASFTEVIELYLEIPTLILLDEISAGLAAP
                     ELDEQFWWGMRFLGSNCEKGKIGFLLTAKESPEKIMLDDNKPSPFFNIFGHVFNLGPFT
                     DAEALNFLNHSPLPFTEEETHWVLQKSGRWPALMQIICHSKLIALEEQSSGNQWRTEAI
                     KRITPYSYLLGKKP"
ORIGIN
        1 aagtttaact tatgtccaat taaatgaaaa agccaatcaa ttggcacatt ttcttaaaaa
       61 tcaatatcac gttcaatcgg atacactgat cggcatttgt attgagcggt ctttagaaat
      121 ggtgattggt ttattaggca ttttaaaagc aggcggagct tatgtgccct tagacccgaa
      181 ttatccccag gaacgattgg cgtggatgtt ggaagacagc cgcgtttcgg tgctattaac
      241 ccaaacctca ttacaaaata ctttacccga acatcaagcg gatattttat gcttagataa
      301 ttgggaaaga ttcgcgcaac aatccactaa gaatttagaa ttagctttaa attcagacag
      361 tttggcttat gtgttattta cttcaggctc tacgggacgg cctaaaggag taatgattga
      421 gcatcaagca ttgcataatt ttttacacga catgcaattg cgacttcaat caaaattaaa
      481 tagttactta ttggcagtta ctacgctatc atttgatatt gctggattag aactttatct
      541 gccgctttta acaggtatgg gtattgtttt aacagaccga gaaacggcaa gtgatggaga
      601 aaaactgcaa gttttattgc aacaatatga tatatgttta atgcaagcaa cacctgcaac
      661 atggaaattg ttattagata ataattggca acaaaataga ccattaacca tcttatgtgg
      721 tggcgaagca ttacccgaaa atttagggca agcattattg caacaaagtg agcaattatg
      781 gaatgtttat ggaccaacag aaacaaccat ttggtcaagc gcacataatg caactcaatc
      841 cccagaacag cccagtttaa ttggtaaacc tttgagcaat acccgaattc atatcgtaga
      901 tacgcaaaat caccccgtcc ccatcggcat tgcaggcgaa ttgtgcattg caggcgatgg
      961 actagccaga ggctatctca atcgccccga tttaaccgcc gagaaattcg ttgaattaga
     1021 attattcggc aaaaccgaac gggtctataa aacaggtgat ttagcccgtt ggttgcctga
     1081 tgggaattta gactatttag gacgaattga ccatcaagtt aaattgcggg gatttcgcat
     1141 tgaattgggc gaaattgaag ccattttaac ccagcaagaa tccataaaag atgccattgt
     1201 tattttacat gagaaagacg gcaataaatc tttagcggct tatcttgttt tagcagataa
     1261 aaacgcggat attagcgatt tacgtgaagt tttaaaagtg aaattacctg attatatggt
     1321 accgacttat ttcaccattt tggataaatt gcctttaaca ccgaatggta aaattgaccg
     1381 taaggctttg cctgaacctg aaaaaagcca tatcacaagc aatcaagaaa ctccgcgtaa
     1441 tcaagctgag ttacaattaa ttcaaacctg gcaaaaagtg ctgaatattc aaaagattgg
     1501 cattcgtgat aacttctttg aactgggcgg acactcactg cttgcggttc aacttatgag
     1561 ccatattcag caacattggc agcaaaaact gcctttagca gtcttgttca gtagcccaac
     1621 gattgctcaa ttggcacagc atctacaaca aaataataca caacacagtt gtctagtccc
     1681 gatacaaatc caaggcagcc aaccgccatt gtattgtctg cctggtgccg gcggccatgt
     1741 tttgtatttg cacgctttag cctgtcatct cggcattgat cagcccctat atggcttgga
     1801 aacaccagga ttgcatgggg aatgccccat gcctgatagt gtagaacaac acgccgcctt
     1861 gctgttacaa gccattcgca aacagcagcc caatggtccc tatcgttttg caggtcattc
     1921 cgcaggagga cgtgtcgcct tagctctggc gcatcaattg gaaaaacaag gcgaaaaaat
     1981 acaatgtctc attatcctag atacaactgc cccacaaata aaccccgaac ccactgccga
     2041 attaaccgaa gtagaagccc tgtggagtgt ggttaagatt gttgaggaat tgaaaaatac
     2101 ccaaatcgat ttgactgaag cagaaatcgc ggcagaatca gatagttata aacgttatga
     2161 acaagtcatg gaacacgtgc aaatcgcggg gatgttcgcg cctcaaacgc cagtcgaaga
     2221 actaaaacat cttgtggcca tttaccaaac gatgattcgt aaccatgctt attatcgacc
     2281 gaattatcaa attaattgcc ctattatttt ggtcaaagct aaagaaattc ctaatgaaac
     2341 tgaacgccca aatagtcttg attggggttg gcaattatat tctacccaaa cggtacaaat
     2401 tatcgaaacc tcaggcggac atatcactat gttgactcaa ccttatgtgg cagagttagc
     2461 ctctttatta acacaggcca tggcaaatac aatgaataaa aatactcagg aaaacttatt
     2521 atgattattg aaataatctt aatcggtggc gcatttggtc tgtggaaaat tcaaaaatct
     2581 acaaaagaat tgactccaca aaatacgata aatatttctg aagtatcgcc cgcaaaagaa
     2641 agaaaacgtc atttattaca cgatattcgg gatgcattgc gtgccgaggg acgacaacag
     2701 ttgcaactcg acattgatcc aaagcaacgc gccttattag aggcccaaga acgtgaacgt
     2761 aagcgtgata tgcaattgtc tttaggggcg atggggcttg ctttgttggg aagtttctcg
     2821 cctactttta ccttaattgg cgcagcagct gtgctgtatt tgtcaaaaga aacctttaaa
     2881 ctgattcata aagattttaa acgcggacat tatctcagtg tttatttaat tggtttaatt
     2941 gtgaccctgg gcatgattgt gacggggaat ttgctcttag cggcttttac gggggtgatt
     3001 ggtggttttt ttgcgggcat tattaatcgc ttagaatccg attcacaaca gcaattaatt
     3061 cgtgtattca gtggccatcc acaacaagta tggctattgc gtgatggggt tgaaattcaa
     3121 attgatttcc atcaattaca agtcggcgat ttagtcattg tcaatgccgg agaagtgata
     3181 cctgttgatg gttctattca gtccggcgaa ggacgagttg accagcattt attgaccgga
     3241 gaaagcgaag ccgtcgagag aacaattggt gaatcggttt atgcgtcaac gctcttgtta
     3301 tcaggacgtt tagtcatcga agtgtcgcaa gcaggcgatg ccaccatggc cgctaaaatt
     3361 ggtgaagtgt taaatcaaac ccaaaattat aaagaaactt tgatgacacg cggtagagtg
     3421 gttgctgacc gttttttacc ggtgactgtg ggtgcaagcg cactcacatt gccgatttta
     3481 gggcccaatg cagccattgc agtgctgtgg tcaaatttgg ggggaattat ggcgcctgca
     3541 ggttcgttaa cggtattgag ttacctacaa attatgtcgc gtcatcagat tttagtgaaa
     3601 gatggacgag tatttgagtc gttaaaacaa gtcgatacga ttatttttga taaaacaggc
     3661 actttaacct tagaacaacc tattgtcagt aaaattcaca cttttgatgc atttactgaa
     3721 gttgaagtgt tacgttatgc cgccgccgcc gaataccgcc aaccgcaccc gattgctaaa
     3781 gcaattatca ccgccgcaca agcacaacag attgatattc cacaactgga tgaagccgct
     3841 tatgaagtgg gttatggcat taaagtggtc gtggaaactc agattattcg tgtgggcagt
     3901 gtgcgtttta tacagcgaga aggcataacc atgccacctg aacttgatct gattcaacaa
     3961 caggccgaca ccgaaagtca ttccctgatt tatgtggcag tggatcataa attggcaggt
     4021 gtgttagaaa tgcagccaag cattcgccct gaaattgaag aaatcattcg ttttcttaaa
     4081 cagcgaaaaa tacaacttta tatcatttct ggcgaccacg aaatcccaac ccgcaaaatg
     4141 gcagaaacat tgggcattga ccattatttt gccgaagtat tgccagaaaa caaagccgat
     4201 catgtcaacc aattgaaagc ccaagggcgt tttgtttgtt ttattgggga tggcatcaac
     4261 gatgcgattg ccttgaaatc agcacaagtc tcaatttcgc tgaaaggggc ttctacggca
     4321 gcaaccgata cagcacaaat catttttgtc gatggcacgc taaaacatct cacttccctt
     4381 ttccaatttg ttgatgaatt tgaacaaaca atggatagaa attacctgat cagtgttgtg
     4441 ccgggagtgg taattattgg tggggtatat ttgttgagtt ttggtattgc gacaagtatg
     4501 gctctatttt atttgagttg ttttgcagga ttgggaaata ctttattgcc tttagttaaa
     4561 caccaaaaca atgagatacc agagctgtct aaatcagaat ctattgattt aaataaaaaa
     4621 tcactggcca tcagtgattc aactgatcag gatttatcct gagtggaata ggttatttgt
     4681 attttggtca agtcaaaatc cgctatggga aaccgttaca ttttttataa aaaaatgggg
     4741 gatcactatg aggattagta ataaatgtta aaataacatg agttcaatat aatcaaagag
     4801 ataactattt gtatctacaa aggtaaactg tttggtgata aaggttacat ttccaaagcc
     4861 cttgcgtcct atgttactgt ctttctctat ggggtgatat cagcaaaagc acattgtagg
     4921 attggattcc cattggctca gcccatctta tcggactgac gttttagcaa aaccacccta
     4981 tcattcaaac tattacaaat cactgatcac atgaaaatta gaaaattaac tgtcaaaaat
     5041 tacaaaatgt ttgacgactt agaattggac tttaccgatt ctaacggcaa agccttagac
     5101 ctgattgtac tgaccggtgt caatggcagt ggcaaaacct ctatattgtc tctcttaaga
     5161 aaactctttt caaaacattc aaatcggttc agatcaaaag ttcccctcat cgactttgaa
     5221 gaagaatcca gtgggatcat ttgcaatgaa atcgtcgtgg aaaccgaatt gactttggac
     5281 caggtttctt ccttggctaa tctcattagc gaatttcaac aaaaagtgac atccaaacaa
     5341 caattattgc ttgatccatc ggtactttct caactagaaa cagttaaaca aaaactttcc
     5401 tccaaaaaag ttcaaccagg cgggcaaata tggtcaccaa tggtgtatgg gcttaaactg
     5461 tgtacatcgg catctggaac catgtatccc agcgttgata acagtggtct tttccctttt
     5521 tctgcaacta ctcaaaaaat ttgctattag cgactcaatt gggctagtgt agagtggcta
     5581 tgactatggg taacggtaac tgcccatttc ttccacaatt cccttcccat cttccaaaaa
     5641 cctcgtcact ttccaaacct gacgaggttt tatttttttg ccagcccgtg tagaataagc
     5701 aactgggcca cccatgactc attagagtga caattaaatt ctttctttcc taaatttcca
     5761 cggaggttta agagttgatt cgtctctctg gaatctttat tatgatacaa tctcagttaa
     5821 cccaaatgac cttataaaac atgaccacct caattcaatc cacttctgac tgggcagaag
     5881 aatggttgct ctacttcaat tacacacttg aatttttgtc caccttaagc taaactaatt
     5941 tttaacatta agaaggaata taacctttga gttttgaagt cgaatacacc gatgaatttg
     6001 gacagtggtg ggaccatctg aatgaaggag aacaagaaag tattgatgcg atagtagatt
     6061 tacttataga atttggtccc caacttaaat acccttatag ttcacaaatt caaggttcaa
     6121 ggcattcacg tttgcgcgaa ttaaggattc aacacaaagg tcaaccttat cgaattttgt
     6181 atgcccttga tccaagacgt atagctattt tactcatagg tggcaacaaa gctggtaatg
     6241 atgattggta taaggagttt atacctatcg ccgagaagct atatgatgaa catttaaaga
     6301 ctttaaccga ggaaaatgat tatgatgact aaaccttacc agttattacg cgaaaaaatg
     6361 tctcccgaat cacgtaagcg tgcccaacag ttagctcaac agctacgtga ggagatgcag
     6421 ttgtcaaaaa ctacttctgg cgggaccaca gaggcaggta aatttcttca gagaagagat
     6481 gaatagtagc cctttcgaac cgccaaggaa tggtaaccaa tggcaaccgt cattttttgc
     6541 tgagttcatc ttccaaaaac ctcgtcactt tccaaacctg acgaggtttt attttttttg
     6601 ccagcccgtg tagaataagc aactgggtga caaagaatta atcatccccc atcattactc
     6661 tgtagcctat caatcttcat caatcaacat cgcccccttg acaaaaggtt tgctttaccc
     6721 ccatcatttt agctatctgt tcataatgaa ttaaacccac taataacctt gcgaaaagca
     6781 ctctggcatg cttaaaaaaa tctatattca caatttcaga aattttgtca attttgaaat
     6841 ggaactggat aacatcaact tgttgatggg aaaaattgga atttgaagct aacaaaatca
     6901 cgcggaagat tgccccattg gggagaggtt cgggagaaca atatgtgcgg gaacagtttg
     6961 ctaaattcat aacggcccat cgtcgtcaag ttaagtgcga gaatgttata ctggtcgttg
     7021 tcacggatgc tgacgaaaag gacgaacatg cttacgagga tcgtctcaac accttgacga
     7081 atactctgac tgaaccgctg tcgaaagcag agaaaatcgt tgttctgatt cccgccaaaa
     7141 acattgaaac ctggtttcgt acggcagaaa gtatgctgaa gacatttgcc ccaacctacc
     7201 accaaatgct cctgttacct tgcaaaaggc acgtatggaa gtggaaagag tgaatgccgt
     7261 ccataaaccc ttttaattgt ttttcagttg acaagggttg caaattgtaa aatagtcgct
     7321 atcattattt ataactttta attttttcat ctctactctt atttatgaat accacctacc
     7381 ttcaaattag catatctaat gccgaccttg ggcaggtagg gtggtgcgat tttttcctcc
     7441 ctcccttctt aatgctgcga ttgttgcccc acagcgggca caacagttaa tcacagctat
     7501 ctttccgcag tcctctatac tcatctgatt taatccttga gtttataact ccccaaataa
     7561 cgtggggccc tttctgtggc ctattattct ctaaaagaag ggaattacca tgactgacaa
     7621 attaattatt tttgatacga ctctaagaga tggagaacag agtcccggcg cttccatgac
     7681 caaggaggaa aaagttcgta ttgccaaagc gttggaaaaa ctccgcgtag atgtgattga
     7741 agcgggattt cctatcgcca gtgtgggtga ctttgaagcc gtccaagccg ttgccaatac
     7801 ggttaaaggc tctgtagttt gcggattggc acgtgcctta gataaggata tcgaacgggc
     7861 tgcagaagct cttaaaggag cggcccaatt tcggattcat acttttttgg ccacgtctcc
     7921 gattcatatg gaaaagaaac tgcagatggc gccggaccaa gtgttagccc aggcggtgca
     7981 tgcggttaaa aaggcacgtc gttatacgga cgatgtggaa ttttccccag aagatgcggg
     8041 acgctcggag attgattttt tgtgccgagt catagaggcg gtgattgatg ccggggctcg
     8101 cactgtcaat attcccgaca cggtgggtta taaattacca gatcgatttg gacagttgat
     8161 ggccacttta ctcgaacgaa ttcccaattc agatcaggct attttttcgg tccattgtca
     8221 taatgatctg ggtctggctg ttgccaattc cttgtccgca gttatgaacg gtgctcgaca
     8281 ggtggaatgc actatcaatg ggttagggga acgggcgggc aatgctgctt tggaagaagt
     8341 ggtgatggcg attcggactc gcaaagatat ttttccttgc catacggacg tggacacgac
     8401 tcagattctc acttgttcca gattggtctc taatatcact ggattcccag tgcaaccgaa
     8461 taaggcgatt gtgggcgcga atgcctttgc gcatgaatcg ggtattcatc aggatggtat
     8521 tctcaaacat cgtcaaactt atgagatcat gaaggctgaa gatgtgggct ggcatgccaa
     8581 tcggatggtg ctgggcaagc attcgggacg caatgcgttt cgagaccgtt taaaaagttt
     8641 aaatatcgag ttgaattcgg aagaattggt caatgcggct tttggacggt ttaaggaatt
     8701 agcggataaa aagcatgaga tttatgatga ggatcttcaa gcgctgatca cggatacctt
     8761 gacgtctgaa catgaagagg ttaaattagt ttccctaaaa gtgtgttcag aaacggggga
     8821 aactcctcat gctcagatca ctcttaatat caatggcgta gaacaatcgg tgggtgccaa
     8881 aggcagcggc cctgtagacg ccacttttaa ggctattgag gcgttgatca acagtcaagt
     8941 cacgttgctg gtatactcgg tcaacaatgt gaccaatggc actgattctc aaggcgaagt
     9001 gggggtgcgt ttggaaaaag aagggcgcgt ggtcaacggt caaggtgcgg atactgatat
     9061 tgtgatcgcc tctgccaaag cctatcttaa tgcgctcaac aaacttttga ccgtgactca
     9121 tcgtcagcat ccccaagtgg tgcaacaggt gtaatggtat gacttattca caggacctca
     9181 cgtcgcgaca tgctcagtat ttacgagcca tgggcattcc aatttgggta cgacgggaat
     9241 ctgctttatt tctcctgccg gtggctgaaa cccaggttcc catggagcat gatggggaag
     9301 agggtcctgt gcatgcaatt gctggcaatc cattaccgac tgctgattct gatactttca
     9361 acattcctcc tcactcagca gttctagagg aggaatttcc cgccattgat tcccaaactg
     9421 cttgtcctcc aactgccaag ccgactgttc cccttcccac tcaacttgtg cctatgacgg
     9481 tctcttcttc ctcatcctcc tcccctttgc tgtcaacaaa ttttacttta tctccagcag
     9541 atgctgcctt ggcttggcag gatttgcaac aacgagtcgc tcattgtacg gcttgtgaat
     9601 tgtgtcaagg tcgcactcaa acggtatttg ggactggcaa catcaatgca gattatctgt
     9661 ttgtgggtga aggacccggg gaggaagaag atgcccaagg actgccgttt gtagggcctg
     9721 cggggcgttt attaaatgcc atgttgtatg ctattaattt acagcgagaa caggtttaca
     9781 ttgccaatgt ggtcaaatgt cgtccacccc aaaatcgcaa tcccaaggag gaagaaatga
     9841 agcaatgtgc ccccttttta caacagcaga ttcagttgat tcaacccaaa ttgattgttg
     9901 cattgggggc agtggcggca caacatttgt tggctaaaaa tactcctatt ggtcaattgc
     9961 ggcaacagca attgtattac caaaatattc ccttgattgc cacttatcac ccggcctatt
    10021 tattgcgacg gccttcggaa aaacgccgat cttggcagga tttgcaattt attcactcca
    10081 cttttcaaca attgccctaa tggacagttc ccccaacctt caattgagaa ccatgcaatt
    10141 tactgatttg actgctattt tggaaattga aaaggtgact caaatttctc cttggagtga
    10201 gcaaattttt gcagattgtt taagagtggg ttatcgggct tgggtcctgg tgcttgatga
    10261 gcaagtgatt ggttacggat tattgtcagt gggtgcagca gaggctcatg tgctcaatct
    10321 ttgtattcat ccctattatc aaggaattgg ctatgggact tgtttattgc aacatttgct
    10381 cgatattgcc tatcaagagg cagtgaaaac tgtatttttg gaagtgcgca tgtccaacca
    10441 gattgcttta catttgtatt tgaagatggg ttttaatcag attggtatac gtaaaaatta
    10501 ctatcttgat ggacaacacg gtaaggaaca tggtctcatc ttggctaagg aattgttata
    10561 agctaagatg atgattttaa gatattattt tgactgataa ggcaactgca tgaaatatcc
    10621 cactattgaa cagtgtgtcg gcaatacccc attgattcgt ttgcaacggt tacccggcaa
    10681 ttcttccaat gtgattttgg ccaaattgga gggacataat cccgccggtt cagttaaaga
    10741 tcgacccgct ttgagcatga ttcaacaggc agaaatgcgc ggagaaattc aacccggtga
    10801 tcatttgata gaagcaacca gtgggaatac tggcattgcc ttggccatgg tggccgcaat
    10861 gaaagggtat cgtttgtcat tgattatgcc ggaaaatatg agcgtagaac gacgcatgtt
    10921 gatgaaagcc tttggggcgc aactggtctt ggtatccaag gaaggcagca tggaagcagc
    10981 tcgggacttg gcattgcaga tggaacgtga ggggcaaggc aaaattctca atcaatttga
    11041 caatcctgac aatccactgg ctcactatca aaacacggga ccggaaattt ggcgagatac
    11101 tcaaggcaga gtcactcatt ttgtcagtgc catgggcacc acaggcacaa ttatgggagt
    11161 ttctcgttac ttgaaacaag tgaaccctgc agtacgtatt gtcggagttc aacctgcaga
    11221 aggcgctagc attcccggca ttcgacgttg gactccagag tatttaccca aaatttttga
    11281 tgcccgacaa gttgatcaga tgatagacat cgatcaagcc gccgccgaat caaccactcg
    11341 agccttggca gttcaagaag gcatttttgc cggcatctct tctggaggtg cagtggctgc
    11401 ggcgttacaa ctggcgcaac agctggaaaa tgcagtgatc gtggttatta tctgcgatcg
    11461 aggagatcgt tatctgtcta ctggagtatt tcctgctgat taagtattat tgacggtcca
    11521 tttcatcacg cctgcatagt atttcaacac gcctactaaa attcgttgaa ttcacaagtc
    11581 attcatgata tgcttatata ctttatcaca ccaagtttca gaaggaattt acatgaaaaa
    11641 attagcctta ttaggatgtt ttatattcag tatggcgcct ggggtacacg ccgaactaat
    11701 gtggggagtc aatgccaatg gcgaggtttt ccgctggata ggtattgatt ggcaacggat
    11761 agaaggccaa ttgaaacaag tttccgtggc cactgacggt accgtttggg gagtcaatgc
    11821 caaagatgaa gtttgggcct atgagaacag caataacaat tggattcaaa ttcccggcag
    11881 tgccaaacaa gtggacgttg ggaacaagga tcacatttgg tccgtggatg ccaaaaatga
    11941 cgttttccgt tggactggca atggttggca acaattggca ggtaaatttt cccaaatctc
    12001 agtcggagca gatggcaccg tatggggcgt taacccacaa aacgaaatct gggcctacga
    12061 tgccaatcaa ggctgggtac aaattcctgg agttttaaaa caagtcgacg ttgccgatgc
    12121 caacaacatc tggggcacca gtgccaatga ccatgtttac cggtggggcg gtccccaagg
    12181 ctggcaacgg gtagaaggca gcgccaaaca agtgtgtgtc ggcgtgaagg gaacggtatg
    12241 gagcattgat gcccaaaatc tggtattccg ttggacgggt caagcctggc aacaagtgcc
    12301 gggtacctta gtacaattgg attgtgccga ttactgattc agttaggata atcactttta
    12361 tcaagtgccc accgatatca aatgatgggt aatataaaaa ggtgtggtct atcatcccat
    12421 ataactgaca cattgcaacc ctggcaaaaa aaccgttgag ccctggtaaa agactcagcg
    12481 gtttttttat ggcatatatt tacctgtaac tgatttaaac actcacttag cccaggctcc
    12541 aaacttaact tggaaaccac attatgactt ctgacaaaaa aaccacccac tttggcttta
    12601 ctcaagttcc cattcacgaa aaagtgcaac gagtaaccca agtatttgcc tcagttgccc
    12661 ctcgctacga tctcatgaac gatctgatgt cattgggcat tcaccgctgt tggaaacaat
    12721 ttaccctcag tttggctcaa gcacgtcccg gagaaatcgt attggacttg gccggcggta
    12781 ctggagactt ggcgttaaaa ttggcagaaa aagtagcccc caccggtcaa gtagtactgg
    12841 cggatatcaa tgcaagcatg ttacaagtgg gtcgagaacg tttatttaac caaggcatat
    12901 tggtgcacta tgcccaagtc aatgccgaac aactgccgtt tgcagacgcc agttttgacc
    12961 tgatcaccct ggcgtttgga ttgcgcaatg tcactgacaa agaagccgct ttacactcac
    13021 tatttcgagt attaaaacct ggagggcgtt tattaatttt ggaattctca gaattgaaaa
    13081 ttaaacctct taaacccttg tatgactggt attctttcaa cattttaccc aaattggggc
    13141 aactgatagc caaagacgct cacagttacc gttatttagc agaatccatt cggatgcatc
    13201 ccaaccaggc acaactgtta tctcttttgg aacaggccgg ttttgaacgc tgtgactgtc
    13261 ataatttgag cggtggcata gtggcagtac atcgaggatt taaactgtga cttcaataac
    13321 ttatgcaggt ttttggcgcc gactggctgc cctatttatt gactcatcgc tgctgggcac
    13381 cctgtttctg attctgaatt atggattgga ttatttctcc attgaaaaaa ttgagcaatc
    13441 accctggcaa ctgtttttag ttaatgacct gttggcagct cttatcatta ttctctattg
    13501 gatacgctgt gcagccaccc caggtaaact attgtttaac tgtgaaatag tgcaagtcac
    13561 cacttacact gcaatcactc ctctccaagc cttgcttcgt taccttggct attttatttc
    13621 cgcgatacca ttgggactgg gttttttatg gattttgcgc gatactcgta aacaaggctg
    13681 gcatgataaa atggcccgca ccgtggtcat tttgcgagat gaatcccaaa tacctttatc
    13741 ccaactcatg aaggaggcgc aatgaaactc ttaactccct ttgaaaaaat actgaaccaa
    13801 tccttgcaat gggacccggt cagtttagct gctttagaac cgctggtggg caaaatcatc
    13861 caagtggaac tgcaaggttt gaacatgacc atttccatat tcccggatca acaaggagtc
    13921 attctgctga ctgattatga aggtcccgct gatgttcgag tcagcgcgcc tcccttcact
    13981 ttattgcgcc aattgctaca atctgaacaa ccgttggctc aacaaaaaat gttaaatata
    14041 gaaggagaag tccatacttt acaacgcttt gtgcacatcc taaaacattt agaaattgat
    14101 tgggaggaac aatgttcccg ctttttgggc gattggcctg ctcatactct gtctcgttgg
    14161 caccaccaag gacaacagta tgcccaacac caattttcca ctttacaacg caattgggtt
    14221 gaatatttac aggaagaagt tcattacttg cctggtcagg ctgaaatgca agattttcta
    14281 aatgaagtgg ctatattaag ggatgatgtg gaaagacttt ctcaacaaat tcaacggctg
    14341 atggcctaat tcatgttgca tttacctatt cggcaaatta ctcgtttatt tggcatttac
    14401 caagtgattg tgcgttatgg tctggatgaa ttgattttat ccacaaagct ctttggtccc
    14461 ttgcacttac tgggctattt aaccccagga tattggttgc gccccaaaca tttgtctcga
    14521 ggcatgcgca ttcgtttggc tttggaagaa ttgggaccta tttttgtaaa attcgggcaa
    14581 attttatcca ctcgtcgaga cctgttgcca gatgatgtgg cggtggaatt ggcccgatta
    14641 caagaccggg tgcctccttt tgatgggcaa ttggctcgtc aaattctcga acgcacctat
    14701 ggtcattctc tggaagaagt attttccgaa tttaatgagc aaccgttggc agccgcttcc
    14761 attgcccaag tccatgcagc ccgtttgcac aatgggcgtg aggtagtgat taaaattgtg
    14821 cgcccgggaa ttaaaccgcg gattcgcaaa gatattgaat tattgtattt atttgctgac
    14881 attgccaatc gttattggag cgaggggcgt cgcttgagac cgcgagaagt ggtggcagaa
    14941 tttgaaaaga atttgtacaa tgaattggat ctgatgcagg aggcagccaa tgccacacaa
    15001 ttgagacgca atttcaatca attggatctg ttgtatattc ccgaagtgga atggaattat
    15061 actcatccca attgtttggt gatggagaga attcatggtg ttcccatcag tgatatagca
    15121 actttaagac aacaggggac taattttaaa tatcttgccg aatctggagt tgaaatcttt
    15181 ttcactcaag tgtttaggga taattttttt catgctgaca tgcacccggg gaatattttt
    15241 gtggatgtga gtcagccagg gcgtccccac tatattgcgg tggattttgg gatcatgggc
    15301 acgttaagtc aacaggatca gcattatttg gccgccaatt ttttggcatt ttttcgacgc
    15361 gattatcatc gagtggcaga attgcatgtg tcttcgggat gggtacctcc aaatacacga
    15421 gtggaagaat ttgaaggagc tattcggagt gtgtgtgagc ctatttttga caggccgtta
    15481 aaggaaattt cttttggatt ggtgttattg cgtttgtttc agacggctcg ccgtttcaat
    15541 atggaagtgc aaccccagtt ggtattgtta cagaaaacat tgttgaatat tgaggggtta
    15601 ggtcgacaat tgtatcccga cttggatctt tggaaaacgg ctaagcctta tttggaacgt
    15661 tggatggatg agcgggtggg atttcgggca ttttttcgag gcattcgcag taatttgcct
    15721 ttgtgggcag aaaagttgcc agatttacca ttgttggtcc atgaaagttt ggtgcaacaa
    15781 cagactcaat cggaacgttt aaagcagttg catcaaggac ttgtggagtt gaaaggggaa
    15841 attcatcatc aacaaaaacg tttgcaatgg gtggtgattg gcagcagttt gttattcagt
    15901 gccagtttga tattgtcatt gcaggcttgg aaattgtgga atatgccgtt gttgggcatt
    15961 gtgttggggg gagcgggatg ttttttgttg ttattggcgt tgtccactgc aaaaaatgtt
    16021 gattgagctt ggttataaca atgagcaggc atgaatatga aacgttatca agatttgatc
    16081 acagaaggtt tacaggttgt ccaagaggtg tttccttggg atgtgcagcc ttggttggaa
    16141 caggtgcccg gacctatatt gttggatgtg cgagaaaatt atgagtttgc tcagttgcac
    16201 attcccaatt ctctaaatgt gcctcgaggt attttggagc aggcttgtga gtatggtttt
    16261 gaggagacag tgccagaatt ggtgaaggct agggatcgga aagttgtggt gatttgtcgc
    16321 tctggcaatc ggagtgtgtt ggctgctttg actttgtcaa ttatgggata tcagcaggtg
    16381 tggtctttaa aaacggggat taagggatgg aatgattttg agttgccgtt gcggaatggg
    16441 cagggggaat tgattgatgt tgatagtgcg gataacttgt tgatttctaa ggttcgagct
    16501 gatcagttgg cgccaaaatt aaaagctcat ggttaaggga caagtgccac cggatcggtg
    16561 gagccgatct ggtggtttca agccagggtt atgggtttag tcggtgcact tgtctccgcc
    16621 cagttcggtg actaaagttg ccatggattt gacgcgttcg gcttgtacgg tggtggctaa
    16681 ctctttggct ttagctacgt ttccagaatc aatcgcggga atgatttcag tttcccgagt
    16741 ggttttgaat tccgtccaca cttcactcaa tttggtcagt tgggaatcgc ccgctttttc
    16801 cttcaaaagg tcagcaatag cagtttcaac tgcagttgaa gctgtgttga tggcggtttt
    16861 cagagcctcg tgttgggttt tgtcagtgga atccaggagg gctactaaac tggcacgagc
    16921 ttcattgaga ttgcttttca cgtcacagat agtggcggct tgggcaaagg gcatgatcag
    16981 gagggaaagg gcggttgcac atccaataag ggttttattc atattgtttc ctaggctaaa
    17041 attgttgtgt aaaggctgag ttactgcaag aatggttttg agttaaccaa ttgacttgtt
    17101 gggttagagt caatatcgaa tattagtata ggagagaaat tggaatgtgc cttgatctag
    17161 gtcaaagtgg aagaaaaagc gcatgtagga taggctgatc aacagtgagg attatcctac
    17221 atgcgcttac cccccccaac cccccccttg gaaaaaaggg ggggctattc ttgatcttcc
    17281 cttggaaaaa aggggggact attcttgatc ttcccttgga aaaaaggggg ggctattctt
    17341 gatcttccct tggaaaaaag gggggttgtt tacttccccc ctcctttgca aggaggggta
    17401 gggggtggtt ctgggcgatt gatgggcttc tcgttggtca gcccattcta catgtgctgc
    17461 gcggaaaaag gcaggttagg ttatcacctg gcataaccta gcagttgagg ggcaagcatg
    17521 tcatttaaga gggttaattt cggtgccaga gtcgttgcca ccaggttttg gagtctggag
    17581 ttccttcttc tggaattttc attttttgac ggattttttg gatgtcccaa ccagtgaggt
    17641 cggccaatcg tcgggcttct ccttcataac gtactcccag ttgttgacga tactgtttgg
    17701 cttcgtcaca tgtttctttt ccttcccaag gatgcctgac gatgtagcgg ccttggaaat
    17761 tttctcgatc agaagtttct tgaaagatga ggtcttcggg aaaggtgtct gcattgtaac
    17821 ggaggtggag gcgggtaaca aatacatcca attccgccca attgtctggg cgtcggtctc
    17881 ttaaccaaaa tacgcccagc tcttgtaatt cttctacgct aagaggatcg gcggcgcaag
    17941 ggtcgcacca gttcatatcc caggcatatt ctaggaaaac ggctcgcatg gattgtttgc
    18001 ggacttgttc ttcaaacagc gcccggtaaa agtcgggaaa ttcctttttg ataaataggg
    18061 gcagttccat attgctgggg agtttgacat ttcggtagtt ggtggtttct acgcggcctt
    18121 tttgagtcag agtgtagata aacagttctt gatctccgtc agcattaagt gttcccaaac
    18181 gaatgggcag gataaatttg ggagattcat aggcaacttg gatgggacgt agataagaga
    18241 agcccagttt ggagtgttct gttaagttga ctttggctac gaaaaatcgg acattttgtc
    18301 gaatgtagct gtccaggact tggttggctt ttttgggaat tttgtagtca ttttcgatca
    18361 accactgttc caacccgtca ctttgttgag cagagagaat gagaatatca tattctccaa
    18421 tggtatattc ggcttctatg gtgactccat ggctattttt tttggagcga atcatatctg
    18481 aactttcact tttaggagcg gcggacatgg caggtccggc ctctcgaagg taaactcggc
    18541 aggggtcgtc gtcaaaatat tcgaccaaac gaggagcagt ataattgtca agatggttga
    18601 tgatttgttt gtccccaatg tgaatttgac cttcttcaat aaaagtgggg accgggatga
    18661 caatggcaaa ttcttgggga tcgcctttga aatcattagc cattgtgagt acagttttgt
    18721 catcttgtcg gactatcaca acttgagagg ctttgttgaa aagttgagtg tctgctttgg
    18781 caacatagaa gccacaaaag ctgtgtacat tagagtagta gatgagcagt aaaaccgccc
    18841 atagactgtg tttcatatta tttttccttg tggattggcc attgataagg ttggttaggg
    18901 agtaaccggt cgataattgg ggtaagtaac gaaaaaaaag ccagtgacca taataaccca
    18961 ttcgtgcgat aaagccaaaa ttggacaaag gcggcgccca aggcaacgag cagggcaaac
    19021 agcaggcgcc cggctcggga atcaggcgtg gttttgggat cggaaagcat gaagaaggca
    19081 aatagtagca gggctccgct ttgcaattga tgtaggggaa tggtcaaagg atcgcccagc
    19141 caagaggcgc gtccaaatag tataatggcg tagaatatta ggaacgctag agtgatgtcg
    19201 gctcgattgg cttggtagat gacccagctg cctaaaccgg caaataacag agccaacaag
    19261 gtcccatttc cccattgacc tggggagacc caaatttgct cggtgagcag gagcaaagtg
    19321 accaagccaa aattggtggg attgaagaga tgcttttctc tccagcggaa aagaaattta
    19381 ctggaaatgg tgatgatggg ggccaatagg agcagggtta tactgttggt acgcagcaat
    19441 aggcagagag acagggcaga aatcagcggg ctttttgcgt caaaaatagg aagggagagg
    19501 tagcgatgat aggcgtattg agttagtatc gcagtacttg gaatcaaaat aatagcccat
    19561 ggattaacgt caaaatcaag aaagaataac ccataaatga gtaaagtact taatatgctt
    19621 atttggtaaa ctcggggatc ataataatga agatgggcaa ataggggttt catgaaaact
    19681 tttgcctttt gatttttaag gattaaggga taactctcct ttgaagagtg ttatcccctt
    19741 taccgcgata aaactatttc aagctggcta acaatctact cgcttgagga gtgcagcctc
    19801 gtcctaccat ccacactact ttatgagaac tggtgggcaa attgctgggg agttgatata
    19861 atatcaactt cttgaacttg gccccagatt gacgattttt caattctacg gtataagtat
    19921 ccccgtatac gataggtaaa ccacttggcc agttcaaggt ttcctgatgg gctggccaca
    19981 tattttccgc aaattcctca gtccgtttat tcttgatcag gagactgtcc gcagtttgac
    20041 tttggttttc tgaacgcaat aaagttacct cattagagga aataaggcag taatgacgat
    20101 cattggcact cacatccacc atccataaag tttctggggg aggcaactgt ccacgaagta
    20161 acggattact ttgaataaat gtggataaag tagtcaccaa ttgagtatcc ggtgtttgtt
    20221 tagaccgggg atctgtgaga taaccgcggt aaggtccctg cacagtttga actcctccgg
    20281 tgggaaaaac caccgtaatc tcagcgttct tagacaagtc taaagccttg gcactgtcta
    20341 aaagttgtcc cgctgcaaaa gcagacgtat tggaatgaat aaccaccgta tccaattcaa
    20401 ccgcttgcac agaaaggctc cctaacatca agcccagtag taatgaaata aacttaaaca
    20461 tggtaatact cctatcaatt taaccaaatc cgaacacctt acacaacaag gccggtatct
    20521 taagtttagc aaattctacc ataaaatggt gaaatatcgc cttaaaaaac accgcatggc
    20581 cagttttctg aaaaaccaag gtaaccatta tggactcatt tctcaccact gtttcaactt
    20641 taccgatttc cttaaccagt tggcagcgca gtccctttgt cattggtcct cctattaccc
    20701 aaccctgtca attttttggc cgagattaca ttctcaaacg tgttttcgac gtttggaaac
    20761 atctaccctt acaacacatt gccattgtag gctccaaacg cagtggtaaa acctcactac
    20821 tgcattattt gagacgtatt attgacaccc ctaaagaaga attgcgaccc gatcaacgca
    20881 atgactggct agcccccggt taccaatggg tatttatcga ctttcaagac ccccgcatgt
    20941 gccatcaaga gggagtattg cgccatattt taaacgaact tgacatgcca gtcccagccc
    21001 cttgcgacct ggccagtttc accgaagtca ttgaacttta tttagaaatt ccaaccctaa
    21061 ttttactcga cgaaatcagt gctggtcttg cagcacctga actcgacgaa caattttggt
    21121 ggggcatgcg ttttttggga agcaattgtg aaaaaggcaa aattggattc ttactgactg
    21181 ccaaagaatc tcccgaaaaa atcatgcttg atgacaacaa accctctccc tttttcaaca
    21241 tttttgggca cgtttttaac ctaggtcctt ttacagatgc cgaagcgctc aacttcctca
    21301 accattcccc acttcccttt actgaagaag aaactcattg ggtactacaa aaaagtggac
    21361 gttggccagc cctaatgcaa attatctgcc actcaaaact gatcgccttg gaagaacaaa
    21421 gttcaggcaa tcaatggcgt actgaagcca taaaacgcat aactccctac tcatatctgc
    21481 ttgggaaaaa accataatcc aactcactgc ttatcaagag tgcagattct cttcaatgcg
    21541 acctcctttc tgcactctac gtatttcctc accgtcaacc aagcccctct ccccaccttt
    21601 attcccatgc gccctcaaaa tctgttttta acccattggt taatcctagg ctggctcctc
    21661 tttagaccct cagcttggcg acaatatctc caacacctcg atccccacct gtcttccaac
    21721 gttgcccttg cggatttaac tggaccccaa tggaaaaatc ctcaactcct caccttattg
    21781 accaccagcc acctcatcgc tcccctctcc atcagcctct tgctcaccct tctgctctcc
    21841 ctctttcaac tgcccactga cactgtagta ctgaccagtt tatacggctt actattcggc
    21901 atttttggcg ggttgttagg cagtctcata gtctccctac ccttcggcat cctcatcagc
    21961 acccttggaa ccctactcct gagcctacct ttagttctca ccggggacat cattttcagc
    22021 atggaaaaaa atatcgccat cctcactgta ttcatggccc cccaagactt tcttaccacc
    22081 acggacttaa accctcctca attctccacc ctactcatcg taaatttggg cattctagtc
    22141 gctggcattg ccggcagtgt catgatgggg accactaaaa atgccaattc ccaaccgctc
    22201 taccaacaaa tcggcagcat agccattggc attgccgtca gcggtctaac cattgccctc
    22261 atcatgctcg ccgttggcac ccttgcctat accatggcca ccctcctgga aaatggcatc
    22321 ctcttcagtt ttgcctatga cagtctcacc accctactgt ttggaatatc cctattctgc
    22381 attgccctgc tccacactgg acactggaaa accgctttca tttgcggaat taccttcagt
    22441 ttaatactgg gaccgctcac ctttctcaaa aacaacctct atgaccttcc ctaccttgcc
    22501 ctgcccctga aagccctaca aggc
//
