LOCUS       c00297_3300000..       11096 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300000347.a:ElkS_mat_CD2ADRAFT_1000639.
ACCESSION   c00297_3300000..
VERSION     c00297_3300000..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 06:15:58
            Original ID  :: 3300000347.a:ElkS_mat_CD2ADRAFT_1000639
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 11096
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..11096
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[8483:11096](-)"
                     /cutoff="20000"
                     /detection_rule="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C) or cds(LANC_like and (Pkinase or DUF4135)))
                     and not (YcaO or TIGR03882))"
                     /neighbourhood="10000"
                     /product="lanthipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(8484..11096)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C) or cds(LANC_like and (Pkinase or DUF4135)))
                     and not (YcaO or TIGR03882))"
                     /neighbourhood="10000"
                     /product="lanthipeptide"
                     /protocluster_number="1"
     cand_cluster    1..11096
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C) or cds(LANC_like and (Pkinase or DUF4135)))
                     and not (YcaO or TIGR03882))"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03603 or TIGR03604 or TIGR03651 or
                     TIGR03678 or TIGR03693 or TIGR03798 or TIGR03601 or
                     TIGR03602 or TIGR03795 or TIGR03793 or TIGR03975 or DUF692
                     or TIGR01193)"
                     /kind="neighbouring"
                     /product="lanthipeptide"
                     /product="bacteriocin"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     region          1..11096
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /contig_edge="True"
                     /product="lanthipeptide"
                     /product="bacteriocin"
                     /region_number="1"
                     /rules="((LANC_like and (Lant_dehydr_N or Lant_dehydr_C) or
                     cds(LANC_like and (Pkinase or DUF4135))) and not (YcaO or
                     TIGR03882))"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03603 or TIGR03604 or TIGR03651 or TIGR03678 or
                     TIGR03693 or TIGR03798 or TIGR03601 or TIGR03602 or
                     TIGR03795 or TIGR03793 or TIGR03975 or DUF692 or
                     TIGR01193)"
                     /tool="antismash"
     protocluster    1..5257
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2:257](-)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03603 or TIGR03604 or TIGR03651 or
                     TIGR03678 or TIGR03693 or TIGR03798 or TIGR03601 or
                     TIGR03602 or TIGR03795 or TIGR03793 or TIGR03975 or DUF692
                     or TIGR01193)"
                     /neighbourhood="5000"
                     /product="bacteriocin"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      complement(3..257)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03603 or TIGR03604 or TIGR03651 or
                     TIGR03678 or TIGR03693 or TIGR03798 or TIGR03601 or
                     TIGR03602 or TIGR03795 or TIGR03793 or TIGR03975 or DUF692
                     or TIGR01193)"
                     /neighbourhood="5000"
                     /product="bacteriocin"
                     /protocluster_number="2"
     cand_cluster    1..5257
                     /candidate_cluster_number="2"
                     /contig_edge="True"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03603 or TIGR03604 or TIGR03651 or
                     TIGR03678 or TIGR03693 or TIGR03798 or TIGR03601 or
                     TIGR03602 or TIGR03795 or TIGR03793 or TIGR03975 or DUF692
                     or TIGR01193)"
                     /kind="single"
                     /product="bacteriocin"
                     /protoclusters="2"
                     /tool="antismash"
     CDS             complement(3..257)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     bacteriocin: TIGR03798"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg297_1"
                     /sec_met_domain="TIGR03798 (E-value: 1.1e-13, bitscore:
                     40.4, seeds: 22, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSIESVNQFFQEVGQDAAMQQQLQSATDKPSFVNKVMELGHQKGY
                     GFSASEVETSLNSLAAQVQSQTGADGELSEDELEAVAGGG"
     CDS             506..622
                     /gene="allorf_00506_00622"
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="allorf_00506_00622"
                     /protein_id="allorf_00506_00622"
                     /tool="antismash"
                     /transl_table=1
                     /translation="LRLREFKGSIPFWKHHSPKQRYLNSSSPLKRANAQNCV"
     CDS_motif       506..532
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: LRLREFKGS"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /prepeptide="leader"
                     /locus_tag="allorf_00506_00622"
     CDS_motif       533..622
                     /tool="antismash"
                     /predicted_class="Class II"
                     /peptide="lanthipeptide"
                     /prepeptide="core"
                     /leader_sequence="LRLREFKGS"
                     /score="-4.70"
                     /leader_location="[505:532](+)"
                     /locus_tag="allorf_00506_00622"
                     /molecular_weight="3335.8"
                     /alternative_weights="3353.8"
                     /alternative_weights="3371.8"
                     /alternative_weights="3389.8"
                     /monoisotopic_mass="3333.8"
                     /aSTool="lanthipeptides"
                     /core_sequence="IPFWKHHSPKQRYLNSSSPLKRANAQNCV"
     CDS             834..1013
                     /gene="allorf_00834_01013"
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="allorf_00834_01013"
                     /protein_id="allorf_00834_01013"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MFLFEYHPLEAPEIPVVFGGGSSELLLLASDNVCINGNKLKVIVT
                     VMLLLNPLRQNFNS"
     CDS_motif       834..893
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MFLFEYHPLEAPEIPVVFGG"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /prepeptide="leader"
                     /locus_tag="allorf_00834_01013"
     CDS_motif       894..1013
                     /tool="antismash"
                     /predicted_class="Class II"
                     /peptide="lanthipeptide"
                     /prepeptide="core"
                     /leader_sequence="MFLFEYHPLEAPEIPVVFGG"
                     /score="-3.40"
                     /leader_location="[833:893](+)"
                     /locus_tag="allorf_00834_01013"
                     /molecular_weight="4151.9"
                     /alternative_weights="4169.9"
                     /alternative_weights="4187.9"
                     /alternative_weights="4205.9"
                     /alternative_weights="4224.0"
                     /monoisotopic_mass="4149.3"
                     /aSTool="lanthipeptides"
                     /core_sequence="GSSELLLLASDNVCINGNKLKVIVTVMLLLNPLRQNFNS"
     CDS             complement(1209..3026)
                     /locus_tag="ctg297_2"
                     /transl_table=11
                     /translation="MLVSEILQVLPASVNWMVLFNLSAIRELADEATIRQMYHLPETID
                     LTPYSHVVLTSHGRFLALLDELQLIEPLSGTGWSHQPSQDSLHDRFSSQLELFPVDEAD
                     CLGLGEKPPFTPVLLHIKIKSGYGEAKAIFEREPSQDHYELLRAVGVTFVAGEFKESYY
                     LAQFQNRLPIHIHAGILSHFSRTAHCNLFFLQHGTIDPPLEAGLLKACQDRVTWARNRG
                     FXALAKLAQEACQQPMAMTCQPPLPGQPFPYGDLVPLGFXLKALNTXASLSIAXSGXIL
                     AARQALSQFLLNQRQGHLWAFHTERXVTSTDSVLVLQGFNXPEAVEALESFADGXGGYY
                     PQLWSSEPQPGKMLFDESSRHWCQSDYATTCLVRALRQDVGLDTKTPVDYLAAGFEHRS
                     GLYFANPYLVDWVLARAIRQDEAAAPWRQKLLAEVLASMNEDYSFGTYDVPMSTALAIL
                     TMATLGFRGRTMGVAQLRLLEFMDSHSLLPAATPFYSSLRLDPKIPAKTLLELLMIDSL
                     APNQSSHRQEQIHQVWGDYHGISFYVDTHQMITTALAVLALSEKCLLEQQDLTLSDYRQ
                     SAVHPRYQCVSHSDYITKFALPPFLRRKN"
     CDS             complement(3013..4167)
                     /locus_tag="ctg297_3"
                     /transl_table=11
                     /translation="MKLRASSIADYLKLVQPHLVPQLISLENWSTINTVAQVLPSAITS
                     FFGFECRLGIKEPQADFLICADAAEAGRKVLAGNDYPITLPDFLTTHPVWSNIRKFSNH
                     WDTNTSPLYQKVRNVWLEFDINESLPTLPIPSCFFGPEPIYQTSAEQRGKLSSPHQWVS
                     QTALKLLLNKALSPQVENQLLKCFDLLPTDAYVFQIGVMLARKSDLVRICIRNISPEQI
                     LNYLTQLNGSGSFHPLKPILIQLSNFVERIDLDLDVGEVIFPKIGLECYLSQQPNYEPR
                     WQLFLDYLVEIGLCLPAKRDALLAYPGCIREISNREIWPPGLLKLSDFLGAGYETVFFR
                     RLHHIKVVYQPDKPLEAKVYLSVNHTLLSPQFISQWREYQNASV"
     CDS             complement(4209..4835)
                     /locus_tag="ctg297_4"
                     /transl_table=11
                     /translation="MKTTLTKCYAQRHNAFPIEYLNDLRSQILSCPYLAASQLSECFAK
                     TKGFSVIFKRSGIGKLEQHFPCFKPYLKVALKQACNVFYLNALVLENGTRVEPHVDCSI
                     SAYGMMFTIPNLVSVLYVQVPQDINGGELVLQTNEHQIGTIQPRTNTLVYFRGDLLHSV
                     NEVKSSHPRISLICEQYNLSETRLEPIPDFAIKSEADTHYNSQVY"
     CDS             complement(5003..6469)
                     /locus_tag="ctg297_5"
                     /transl_table=11
                     /translation="MDNIISFARGAQIRPLNASDRLCYAIQPFIQEIFDQFLALNDLGQ
                     AITQAAKNHEKVVDTLFDIDPNNIEATFSLKPEFLFLNENPLLAFSFGNARYPNFLGKN
                     GMELIKDESILPEIHTLLYLCGQSKLSYNQICQQLSDPMIKLLDKLIKCSVVKEESHWA
                     KGVPPETPGVFRLQHAALLYRTKTTGILVDPHLHSNYGLSTLKNDITRAKLEGSVDAIL
                     ISHSHYDHWHYPTLMMFAPETPIIVPKVPRGTIMCEDMQARLNSLGFKQVIAVDWYAEP
                     IRVGDVEINVLPFYGEQPLVPEFNQPIHPDLRNWGNTYLLRTEYYTSWFLIDAGTDPMG
                     SMAQVADYVKQKFGTVEQVISNFQPLSYNSIGTNLSSWGIDIVANLLSNPQIFSVTNKK
                     EGGHLSTLGPQGVAEICAIVNAQSCLPYADSWAELGQPGVHDEVLIPEVEAALRHLGCS
                     TTVIPWTIGDGYVTTNGQIPGQVLLKNAIS"
     CDS             complement(6751..6900)
                     /gene="allorf_06751_06900"
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="allorf_06751_06900"
                     /protein_id="allorf_06751_06900"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MSIAILNRMQQAKCSKSRYSKGFILKNCHNLNRIAISHQTYAFGT
                     DKFR"
     CDS_motif       complement(6865..6900)
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MSIAILNRMQQA"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /prepeptide="leader"
                     /locus_tag="allorf_06751_06900"
     CDS_motif       complement(6751..6864)
                     /tool="antismash"
                     /predicted_class="Class II"
                     /peptide="lanthipeptide"
                     /prepeptide="core"
                     /leader_sequence="MSIAILNRMQQA"
                     /score="-7.10"
                     /leader_location="[6864:6900](-)"
                     /locus_tag="allorf_06751_06900"
                     /molecular_weight="4225.8"
                     /alternative_weights="4243.9"
                     /alternative_weights="4261.9"
                     /alternative_weights="4279.9"
                     /alternative_weights="4297.9"
                     /monoisotopic_mass="4223.2"
                     /aSTool="lanthipeptides"
                     /core_sequence="KCSKSRYSKGFILKNCHNLNRIAISHQTYAFGTDKFR"
     CDS             6812..6943
                     /gene="allorf_06812_06943"
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="allorf_06812_06943"
                     /protein_id="allorf_06812_06943"
                     /tool="antismash"
                     /transl_table=1
                     /translation="LWQFFKMKPLLYLDFEHFACCILFRIAIDILINYYQTSPIPRT"
     CDS_motif       6812..6868
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: LWQFFKMKPLLYLDFEHFA"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /prepeptide="leader"
                     /locus_tag="allorf_06812_06943"
     CDS_motif       6869..6943
                     /tool="antismash"
                     /predicted_class="Class II"
                     /peptide="lanthipeptide"
                     /prepeptide="core"
                     /leader_sequence="LWQFFKMKPLLYLDFEHFA"
                     /score="-7.30"
                     /leader_location="[6811:6868](+)"
                     /locus_tag="allorf_06812_06943"
                     /molecular_weight="2773.3"
                     /alternative_weights="2791.3"
                     /monoisotopic_mass="2771.5"
                     /aSTool="lanthipeptides"
                     /core_sequence="CCILFRIAIDILINYYQTSPIPRT"
     CDS             complement(7284..7706)
                     /locus_tag="ctg297_6"
                     /transl_table=11
                     /translation="MASVSPSIRQQVISDANQCCEYCQTQQRLIGMPLVIDHIMPRSIG
                     GSSDRANLAASCYRCNQFKGARTTAVDPLTGEPVSLYNPRQQTWAEHFAWIETGTQIAG
                     LTATGRATVDALKLNNQYVLESRRLWVAENWHPPNF"
     CDS             complement(7713..8123)
                     /locus_tag="ctg297_7"
                     /transl_table=11
                     /translation="MQLTIDLPESAVVRLSRLAELTNQPLSELVIQSIAGNLPPAIDTA
                     PAQMQAELLTLQTLSVDRLRQIAQSQIDSDQQERHLALLDRNQEGTLTEAEQQELRDLA
                     LAADQLMLKKAHACAILRWLGQPIRDLNQLSP"
     CDS             complement(8484..11096)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide: DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070:lanthionine synthetase C family protein (Score:
                     841.8; E-value: 1.3e-254)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg297_8"
                     /sec_met_domain="LANC_like (E-value: 4.3e-62, bitscore:
                     198.9, seeds: 47, tool: rule-based-clusters)"
                     /sec_met_domain="DUF4135 (E-value: 6.5e-108, bitscore:
                     350.2, seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="IDFWVEATAEFLNRLATDWLEIQQCFSEDTPLEQVIALKPNLSDS
                     HNRGRSVIALTFNTGLQLVYKPKDLGLDVVFYQLLDWCNQHGNSSSLFSPRLPGTQGDT
                     PLAFKILQVLNRSTHGWVEYVESQPCEDEAAVQRFYQRSGMLLCLVYALQGTDCHYENL
                     IASGEHPVLVDLETLLHHRLKTVGSIKSDAPTLAYQQLSESVLQTHLLPQWGILLHDPL
                     SIDLSGLGGVEEQQQSVPKLENLNMDAMALSYKTVSFKQANAPTLNGTPLSPEDYLEDL
                     VAGMTQMYRLLMSQKAELFAPDSPLMFLAHQNVRFVFRATNTYAVILQKSFQPSLLGTG
                     IDRSIGLDVLSRGFLTMEEKPIFWQMLAAEVQAMEQLDIPFFPADSSSHSLKLPTGVLI
                     PEVFEEPSFDRMLRRLATLSEADLTQQIEIIWGSFYSRFIQEPSPVSGEVSPVPCLRVT
                     EVVTSEQLVQQAITIAEDLQQRAICATDGSVTWIGMGYRHRNQGFQLQGLGYSLYDGSC
                     GVALFLAALAKITGDSQWHELALGTLQPLRHALADSEPDSVARLTRQLGISGTTGLGSI
                     VYALTKISQLLQESALLADARTAASWITPDKIAADQTFDVMEGAAGVILSLLSLHEVET
                     GNQGQQPTPLEFAIAWGEHLLEHQTSIDHRPKTWKTGNGKQLTGFSQGAAGIAYALLRL
                     FAVTQDCRFLNAATDAIAYEQSVFSTEAQNWLDLRSEEPCFRVSWAHGASGIGLGRLGG
                     LSVLDTVEIRQEIAIALETTQKYILGNVNNLCWGTLGRIETLLVAAQRLNRPDLLEFVD
                     QAVTWILAQAQQQGCCISCSDLPSKVYNPGFFHGATGIGYQLLRIANPQLLSSVLLWQ"
ORIGIN
        1 aatcctcctc ctgccacggc ttccaattca tcctcggaca actcgccatc ggcacctgtc
       61 tgactctgga cttgggcagc aagtgaattg agcgatgtct cgacctcact ggcgctgaaa
      121 ccgtagcctt tttgatgacc cagctccatc accttattca caaagctggg tttatccgtt
      181 gccgattgca actgctgttg catagccgca tcttgcccta cttcttggaa aaactgattg
      241 acgctttcaa tagacatctg atttctcctt tgttttgttg ttggtttgac tgaacacaga
      301 cacgaacagt tggcagcctt atcggtagtt atctgtttct tataaaagtc atttttttga
      361 cttaacctgc ttttctattg gtctaatgtt ctctattatt agactatatt tttgatcgga
      421 taagaatacc agtttatttt gggaaaatgg atttccaata ttggcaaaaa tatagatata
      481 acctgttacg catttaattt gctttttgag gctgcgggag ttcaagggga gcatcccatt
      541 ttggaaacac cattctccaa agcaacgata tttaaatagt tcaagccctc taaaaagagc
      601 taacgcgcaa aattgtgtgt gatcctccca tttcaagaga gcaaagaaag cagggggaga
      661 ggatttgaac gcttttatac tgcgtttaaa atgtctaaat taaatgcact tcagcttagg
      721 aataaagaca ctttcagagt ctaacgatga gcctaaaggt gtaccttatg taattgagaa
      781 atgctatcgc tattatgtca ctctggaaaa agtaaaatca tagccaaata aagatgtttt
      841 tgtttgagta tcatcctctg gaagcgcctg aaattcctgt agtcttcggc ggggggtcat
      901 cagaattatt actgctagct agcgataatg tatgcattaa tggcaataaa ctcaaagtaa
      961 tagtgacggt aatgctactt ttaaaccctt tgcgccaaaa ctttaatagc tgagttttga
     1021 tagtcatctt ccccctctta caaacccccc tctctacgtt cgctaacgca gtccaggctt
     1081 tttgctgaga tgtagtagga ttactagagg aaatacctct tccataaaaa aacttcattt
     1141 ttttttgtct ttcaatttac taattttttt ctttaattaa aaagaaaaat aaaactcaac
     1201 ttccatcgtt agttttttct cctcagaaaa ggaggaagcg caaacttggt gatatagtcg
     1261 gaatgactga cacattgata acgcggatga actgccgact ggcggtaatc gctcaacgtc
     1321 aaatcctgtt gctccagtaa acatttttct gatagggcta atacagccag agctgtagta
     1381 atcatttgat gcgtatcaac atagaaagaa atgccatgat agtctcccca aacttgatga
     1441 atttgttctt ggcgatggct tgattgattc ggagccaaag aatcaatcat tagtaattcg
     1501 agtaaagtct tggcaggaat tttcgggtca agtcgtaagc tggagtaaaa tggtgttgct
     1561 gcgggcaaaa ggctgtgaga atccatgaat tctaacagtc gtaattgagc cactcccatt
     1621 gtccgccctc taaaccctag ggtagccatc gttaggatag ctaaagcagt ggacatcggg
     1681 acatcataag tgccaaaaga atagtcctca ttcatgctgg caagaacctc agccagaagt
     1741 ttctgtcgcc atggtgcggc tgcttcgtct tggcgaatcg cacgggctaa aacccaatcc
     1801 accaggtaag gattggcaaa atataaacca ctgcgatgct caaaccccgc tgctaagtaa
     1861 tcgactgggg ttttggtgtc tagtccgacg tcctgccgta atgccctgac cagacaagtt
     1921 gtggcataat cagattggca ccaatggcga gagctttcat caaacagcat ctttcccggt
     1981 tgtggctcac ttgaccagag ttgaggatag taaccgccnt gcccatcagc aaagctttcg
     2041 agcgcctcta cggcttctgg ntgattgaac ccttgtagta ccaacaccga gtctgtagaa
     2101 gtgacnaatc gctctgtatg aaaagcccaa agatgacctt gacgctgatt cagtaaaaat
     2161 tggcttaatg cctgacgcgc tgctaaaatn gnccctgant cagcgatnga taaagatgct
     2221 gnggtattca acgcttttag ganaaanccc agaggaacca agtcnccata ggggaaaggc
     2281 tgacccggta gaggtggctg acaggtcatt gccatgggtt gctgacaagc ctcctgtgcc
     2341 agttttgcca aagcatngaa accgcgattt ctcgcccang tcactcggtc ttggcaggct
     2401 ttgagtaagc cngcttctaa aggtggatct atagtaccat gctggaggaa aaacaggttg
     2461 caatgtgctg tgcggctgaa gtgagacaaa atcccggcat ggatatgaat cggtaaacgg
     2521 ttttgaaact gggctaaata gtaagattct ttgaattctc cagccacaaa ggttaccccc
     2581 acggctcgga gtaattcata atggtcttga gaaggctctc gctcaaagat tgcttttgct
     2641 tctccataac ccgatttaat tttaatatga agtaagactg gggtaaaagg aggcttttca
     2701 ccgagaccca ggcaatcggc ttcatcgacg ggaaatagtt ctagctgact tgaaaatcgg
     2761 tcatggaggg aatcttgact cggttgatga gaccaacctg ttccggataa gggttcaatg
     2821 agttgcaatt catccagcaa tgccaaaaat ctgccgtgac tggtgagaac gacatgactg
     2881 taaggtgtca agtctatcgt ttcgggtaga tggtacattt gtcggatagt tgcttcatcc
     2941 gccaactcgc gaatggcaga taagttgaac agcaccatcc aatttacaga agccggaagc
     3001 acttgtagga tttcagacac tagcattttg atattctctc cactgactaa taaactgcgg
     3061 actaagtaag gtatggttta ccgaaagata caccttggct tctaagggtt tatccggttg
     3121 gtaaaccact tttatgtggt gcaatctccg gaaaaagact gtttcatatc cagctcccag
     3181 gaagtccgat aatttgagta aacccggggg ccatatttcc cgattagata tttctcgaat
     3241 gcatccagga taagctaata gggcatctcg ttttgccgga agacagagtc ctatttcgac
     3301 taaatagtca agaaagagct gccatcgggg ttcatagtta ggttgttggc tcaagtaaca
     3361 ctccaagcca atcttaggaa aaatgacttc gcctacatct aggtctaaat caattcgttc
     3421 tacaaaattg gataactgaa ttagaattgg tttgagcggg tggaaagaac ctgacccgtt
     3481 cagttgggtt aaatagttta atatctgctc gggagagatg tttcggatac aaattctgac
     3541 taaatcgctt tttcgagcca gcatcacccc aatttgaaaa acgtaagcat ctgtcggtaa
     3601 taaatcaaag cactttaaga gttggttctc gacttggggg gacagtgctt tgttaagcag
     3661 aagctttaat gctgtttgag aaacccattg gtgaggcgac gacagctttc ccctttgctc
     3721 cgctgaggtt tggtaaatcg gttctggacc aaaaaaacaa ctgggaatgg ggagggtagg
     3781 aagagattca ttgatatcaa actctagcca gacattacgc actttctgat aaagaggaga
     3841 ggtattggta tcccagtgat tgctaaactt gcggatatta ctccatacgg gatgagtggt
     3901 gaggaagtct ggtaaagtaa tcggataatc gttacctgcc aaaaccttac gtccggcttc
     3961 agccgcatca gcgcaaatca aaaagtcagc ctggggttcc ttgatgccta agcgacactc
     4021 gaagccaaaa aaagaggtaa tggcgctggg taaaacttgg gcgactgtgt taatcgttga
     4081 ccagttttct agagaaatga gttgaggaac caggtgaggt tggacaagtt ttaaataatc
     4141 ggcgatagaa ctagcgcgta atttcatgac aggtgaagta aaaggttgaa taatcgggca
     4201 attcagactc agtaaacctg tgagttataa tgtgtatctg cctcagattt gatggcaaag
     4261 tctggaattg gctccagtcg agtttcgctc aagttgtatt gttcacagat gagactaatt
     4321 cgggggtgtg aacttttgac ttcgttgact gaatgaagca aatcgccacg aaagtaaacc
     4381 agggtgttgg ttctaggttg aatagtgcct atttgatgtt cgtttgtctg tagtaccagt
     4441 tctcctccgt tgatatcctg tggaacttgg acgtataaaa cactcaccag attgggaatg
     4501 gtgaacatca tgccataagc ggaaatacta cagtcaacgt gtggctctac tcgagtgcca
     4561 ttttcgagta ctaaagcatt taaataaaag acgttacagg cttgcttcag ggctaccttt
     4621 aaatagggtt taaaacaggg aaaatgctgt tcaagtttac cgatgcctga gcgtttaaag
     4681 atgactgaaa agcccttcgt tttcgcaaaa cactcactga gttgactggc ggctaaatac
     4741 gggcaagaca ggatttgcga tcgcaagtcg ttcaagtact cgatgggaaa ggcattgtgc
     4801 ctctgggcat aacatttagt cagagtagtt ttcatggtgg aaattgttcg ttttcactga
     4861 aaaagctgta agtactgatc ctaggaaata gactcagttg attgactaat aatttagtca
     4921 tcctcggacg aaaatttata tattcaagtg ccctagtgat taagagtatt ttggggcaat
     4981 ggatacaact ttaaacagga gactaactga tggcattttt gagcaggact tgtcctggga
     5041 tttgaccatt agttgtcaca tatccatcac caattgtcca agggataaca gtcgttgaac
     5101 atcccaaatg tcttaacgct gcttcaactt ctgggattag tacttcgtca tgtacacccg
     5161 gttgtcctag ttcagcccaa ctgtcagcat aaggcaagca cgattgggca ttaacaatgg
     5221 cacaaatttc tgcaactcct tggggtccaa gggtagagag atgtcctcct tcttttttat
     5281 tcgtcaccga gaaaatttga ggattgctga gtaaattggc aacaatatcg atgccccaac
     5341 tggataaatt tgtaccaata gagttgtagg ataaaggttg aaagttactg ataacctgtt
     5401 ccacagtacc aaatttttgt ttgacataat ctgctacttg agccattgaa cccatgggat
     5461 cagttcccgc gtcaatcaag aaccaggagg tgtagtattc tgtgcgtagc aaataggtgt
     5521 ttccccagtt tcgtaaatcg gggtgtatgg gttgattaaa ttcgggaact aaaggctgtt
     5581 ctccgtaaaa agggaggacg ttaatttcca catctcctac ccgaataggt tcagcatacc
     5641 agtcaacagc aatgacctgt ttaaacccca aactgtttag tctggcttgc atatcctcac
     5701 acataattgt ccccctaggg actttgggaa caataatagg agtttcggga gcaaacatca
     5761 tgagagttgg atagtgccaa tgatcatagt ggctatgaga aattaaaata gcatcgacgc
     5821 ttccctctaa tttggcacga gtgatgtcat tttttaatgt agagagtcca taattggaat
     5881 ggagatgagg atctacaaga atccctgttg tcttggttct atataacaaa gccgcgtgtt
     5941 ggaggcgaaa aactccaggg gtttctggag gaactccctt cgcccaatgt gactcttctt
     6001 tgacaacgct gcacttgatt aatttgtcca ataacttgat cattgggtca ctgagttgtt
     6061 ggcaaatttg gttataggac aactttgact gaccacagag atagagcaga gtatggattt
     6121 ctggcaatat cgactcatcc ttaatgagtt ccatgccatt tttgccgagg aaatttggat
     6181 atctggcatt accaaaagag aaggctaaga gtgggttttc gttgagaaaa agaaattcag
     6241 gcttcagcga aaaggttgct tctatgttat tagggtcgat gtcaaataag gtgtcaacga
     6301 ctttctcatg atttttggct gcttgggtaa tagcttgacc taaatcattt aacgctaaaa
     6361 actgatcaaa gatttcctga atgaacggtt ggattgcata gcagaggcga tcgctggcgt
     6421 tcaaggggcg gatttgcgct cctctggcga aggagataat attatccatt gaaattagtc
     6481 tctaaatcac tcattttatg ggatcagatt cagtctattt tgtactttgg ttagcttctt
     6541 ttaagtttta gcgattcgct gagttgctac aagaacggct tgagggattt aatgcttatc
     6601 gctgaaatct ccttacagcg ctttctcaat tccacgaggt agagatgacc gtcaatgaca
     6661 gttttaatct atcgccctat cttaagttag tcaatttaga aaaactcagg tttattcaga
     6721 aaattacata agtgaattaa aactctgaag ttatctgaat ttatctgtgc cgaatgcgta
     6781 tgtttgatgt gatatagcaa tcctatttag gttgtggcaa ttttttaaaa tgaaaccctt
     6841 gctatacctg gatttcgagc atttcgcttg ttgcatccta tttaggattg ctatagacat
     6901 tttaattaat tactaccaga catcccctat ccctagaacc tgagttcgac ttaagctcca
     6961 taagctgaaa acaagtcaac aagagattta cagccatttt tgagtttgga tcaagtcatg
     7021 cgatcgcaac ttttttagtt tcacggcgta atagtttttg aggagtctag ttttggctgt
     7081 atctggatca agtcatgcga tcgcacatct tttggtttca cggcgtaata gtttttgcca
     7141 tcaagcgcta ctttgccgaa ggctttctca agagtgattt tcagcgggcg ttgaatactc
     7201 gcttgcacat ccacggcaat cccaaagccg ccaaaatgcg ctcgatgtgc ggacaccgtg
     7261 gcgtgccagg taatatccgt ttgtcaaaaa ttgggtggat gccagttttc ggcaacccat
     7321 agtcggcgcg attccagaac atattggtta ttgagtttga gggcatcgac agtggcacga
     7381 ccggttgccg tcaaacccgc aatctgtgtt cctgtctcta tccaggcaaa atgttcagcc
     7441 caagtttgtt gacgcgggtt gtatagggaa acgggttcgc ccgtgagcgg gtcaacggct
     7501 gtggttctag cccccttaaa ttgattgcag cgataacagg atgcagcgag gttagcgcga
     7561 tcgctgctgc cgcctattga acgaggcatt atgtggtcaa tgacaagtgg cattccgatt
     7621 aaccgttgtt gagtttggca gtattcacaa cattgattgg catctgaaat cacctgttgg
     7681 cgaattgacg gtgaaactga agccattgct atttagggtg atagctggtt caaatctcgg
     7741 atcggctgtc ccaaccagcg caaaattgca caagcatggg ctttcttgag catcaattga
     7801 tcggcggcta aggcaaggtc gcgcaactcc tgctgttctg cttctgtcaa tgttccctcc
     7861 tgattgcgat caagcagtgc cagatggcgt tcctgttggt ctgaatcaat ctgactttgg
     7921 gcaatttgcc gtagccgatc tacacttagc gtttgcaggg ttagcaattc agcctgcatt
     7981 tgggctggag ctgtatcaat ggcagggggt aagtttccag caatactctg gatgactaac
     8041 tctgacaggg gttgattggt caactcggca agacgagaca agcgaacaac agcagattct
     8101 ggtaggtcta ttgtcagttg catagtaatt tggtggaggt tcgcgtcact atggctgaaa
     8161 gccccgaagt atgggcaatc actacaaatg agcggctagt tacacgagta caaaatatta
     8221 tcatatcacc tcaaattact gatatttaat ccggtgaaaa aggagattgt tcagttaccc
     8281 gcccgtttat ccggagagga tatcttacgc ggctttctat tagagttacc gatttttcta
     8341 gaataatctg cgatctgggt tgaagtgacc attgaatcgg gcgcacgtca gtgcgcccct
     8401 acggtttcgg gggtaaggtt aattcatcaa ataaggtctg tcacgccact acttttaagg
     8461 aatagggagt taccccattg atatcactgc cacagtaaaa cagaagacaa caattgggga
     8521 ttggcaatcc gtaagagttg gtaaccaatt ccagtagcgc catgaaaaaa gccagggttg
     8581 taaaccttcg acggtaaatc cgaacaactt atgcagcagc cttgctgttg tgcttgggca
     8641 agtatccagg taacagcttg atcaacaaac tccaaaagat ctgggcgatt taacctttgg
     8701 gcggctacta acaacgtttc gatccgacct aaagtccccc agcaaagatt gtttacattc
     8761 ccaagaatat atttttgagt cgtttccagg gcgatcgcaa tttcctgacg aatctctacc
     8821 gtatccaaaa cggataaccc ccccaatcgc cctaacccaa tcccagaagc gccatgcgcc
     8881 caactcactc gaaaacaagg ttcctcagat ctcaagtcga gccaattttg agcctcagtg
     8941 gagaacacac tctgttcata ggcgatcgcg tcagtcgcgg cattgagaaa ccgacagtct
     9001 tgggtaaccg caaataaccg caaaagggca taggcgatgc cagcagcacc ttgggaaaag
     9061 ccagtcagtt gtttgccatt cccagttttc caggttttag ggcgatgatc aatgctagtt
     9121 tgatgttcca gaagatgctc accccaggcg atcgcgaatt ccaagggagt cggttgttgc
     9181 ccctggttcc ctgtctcaac ctcgtgtaag cttagaagac tgagaattac tccggctgca
     9241 ccctccataa catcaaacgt ttggtcagca gcaatcttgt cgggagtaat ccaggaagct
     9301 gctgtccgag catctgccag caatgctgat tcttgcagca gttggctgat tttggttaag
     9361 gcgtagacga tagaacctag cccagtcgtg ccactaatcc ccagttgtcg ggttaatcgg
     9421 gctacagagt caggttctga atccgcaaga gcatggcgaa gcggctgtaa ggttcccaag
     9481 gctaactcat gccactgcga gtcacctgta atctttgcca aagcagcaag gaacagagca
     9541 acgccacaac tgccatcgta taaactatat cctaaaccct gaagctggaa gccctggtta
     9601 cgatgccgat atcccatgcc aatccaagta acgctaccat cagtggcgca gatggctcgt
     9661 tgctgcaagt cttccgcaat ggtaattgcc tgttgcacta attgttctga cgttacaacc
     9721 tctgttactc tcaagcaagg aaccgggcta acctctccag agacaggact gggttcctgg
     9781 ataaaccggg agtagaaaga accccaaata atctcgattt gttgagtcaa atcagcttca
     9841 cttaacgtcg ccaaccgccg aagcatacgg tcaaaactgg gttcttcaaa cacttctggg
     9901 atgagtacac ctgtcggtag cttcaggcta tggctggagg agtcagccgg aaagaaaggg
     9961 atatctaact gttccatagc ttgcacttca gccgccaaca tttgccagaa aatcggcttt
    10021 tcctccatgg tgagaaagcc tcgactcaaa acatctaagc caatactgcg atctatacca
    10081 gtacccaaca aacttggctg gaaagatttt tgtaaaataa cggcgtaggt attagtagcc
    10141 cgaaacacaa accggacgtt ttggtgagcc aggaacatta aggggctgtc gggggcgaat
    10201 agctctgctt tctgggacat gagcaagcga tacatctgcg tcatacctgc caccaagtct
    10261 tctaaataat cctctgggga taggggagtc ccgttgagag tgggcgcgtt ggcttgcttg
    10321 aagctaactg ttttataact tagagccatt gcgtccatgt tgaggttttc cagcttgggg
    10381 acagactgct gttgctcctc aactcctccc aaaccactga gatcgatgct taacggatca
    10441 tggagcaaaa tgccccattg gggtaaaagg tgggtttgta agactgattc gcttaactgc
    10501 tggtatgcca acgtaggagc atcagactta atcgaaccta ctgttttaag ccgatgatgc
    10561 aacagggttt ctaaatccac cagcacagga tgttcaccgc tagcaatcag gttttcatag
    10621 tgacaatctg ttccttggag ggcatagacg aggcacagca gcatccctga gcgctgataa
    10681 aagcgttgaa ctgctgcctc atcttcacaa ggctgtgatt ctacatattc tacccagccg
    10741 tgagtggaac ggttgaggac ttgcaggatt ttaaaggcta aaggagtatc cccctgagtt
    10801 cctggtaatc ggggggaaaa taaggaagaa ctgtttccgt gctggttaca ccagtctagc
    10861 aactgataaa aaacgacatc caatcccaaa tccttgggct tataaaccag ttgcagcccg
    10921 gtgttaaacg tgagcgcgat tacagagcgt ccccgattgt gcgagtctga taagtttggt
    10981 ttcagagcaa tgacctgctc taacggtgtg tcctccgaga agcattgttg aatctctaac
    11041 cagtctgtcg ctaaccgatt gaggaattcg gcagtggctt ctacccagaa atcaat
//
