LOCUS       c00438_3300000..        4432 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300000347.a:ElkS_mat_CD2ADRAFT_1003281.
ACCESSION   c00438_3300000..
VERSION     c00438_3300000..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 06:15:58
            Original ID  :: 3300000347.a:ElkS_mat_CD2ADRAFT_1003281
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 4432
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..4432
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1:3244](-)"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(2..3244)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..4432
                     /SMILES="NC(C(C)C)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..4432
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="(cds(Condensation and (AMP-binding or A-OX)) or
                     (Condensation and AMP-binding))"
                     /tool="antismash"
     CDS             complement(2..3244)
                     /NRPS_PKS="Domain: AMP-binding (35-436). E-value: 1.6e-112.
                     Score: 367.8. Matches aSDomain:
                     nrpspksdomains_ctg438_1_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (546-618). E-value: 5.4e-18. Score:
                     56.7. Matches aSDomain: nrpspksdomains_ctg438_1_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (638-939). E-value:
                     4.1e-101. Score: 329.6. Matches aSDomain:
                     nrpspksdomains_ctg438_1_Condensation_LCL.1"
                     /NRPS_PKS="type: NRPS"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     370.9; E-value: 1.4e-112)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg438_1"
                     /sec_met_domain="Condensation (E-value: 7.1e-75, bitscore:
                     238.9, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 6e-123, bitscore:
                     397.5, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.3e-16, bitscore:
                     48.2, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNSPLSLPEFKHHKLLQKWTTTQTDYPYNSTIHDLFQRQAAKSPD
                     AIAIAYQNQQLTYQELEQQSNQLAQYLQSLGVTTETLVSFYLERSPELIITILAILKAG
                     GAYLPLEPSTPPQRLNTILADAQAPILITQKNKLTALPKLPDSLHLLCLDDYFNSTTSS
                     PPVPPTHHVNSHNLAYVMYTSGSTGKPKGVCVPHRGVVRLVKNTNYAHFGADEIVLQLA
                     SIAFDAATFEIWGALLNGGKLVLMPAKIPSLPEIATAIKEHKITTLWLTAGLFHLMVEE
                     QIESLKPLRQLLAGGDVLSIPHVKKVLTKLPNCQLINGYGPTENTTFTCCHQITIEDTT
                     KPSIPIGRPIANTQVYILNPDLQPVPIGHPGELYIGGDGLARGYLNQPDLTQERFIANP
                     FSQESNSRLYKTGDKVRWREDGVIEFLGRFDFQVKIRGFRVELAEIEAVLQDYPNVRNV
                     VVLAREDQPGDKRLVAYLVPEDHHQTLNSTHIKSFLLKKLPSYMIPSAFIVLEQFPLNI
                     NGKVDRKALPVPHRNLGSNRQFVQPRNPAEHQIAAIWQEILGFEVGVNETFTDLGGNSL
                     QATRILSRIRDGFGVDIPVSAMLQDCNSSAATVASLAEYVTHRAIQEDVSDINPVKAIP
                     HGDSLPLTVYQERIWLLAQRAEQHPIYNLPMVFRLQGSLNIALLEKAINQVIKRHESLR
                     TIFAVVNGLPRQQILPELTLKISVVDVITKPLSQAEEEQYIQTLINQEASHPFNLQADP
                     LIRVKLFQLRTDDFILMITCHHIISDGWSLSVLLNEISLFYTHFIQERQLDLPELTVNY
                     GDFTLWHQQRQQETETSLLNYWTNQLMGALPLLNLPTDHPRPAIQTFKGTIQYFHINQD
                     IKTQIESFSQAHSATLFMVLVAVFQTLLHRYSNQDDIVMGSPIASRNYSSLENLIGCFA
                     NIIPLRTHTHXNPSFLEFLAQVKKVSLEGYTHLDFPAEKVLSNFKYKRNLSYYPWFQVV
                     FILLNVPQTDFELPGLKVTEKKFNKGAAICDLVFLVEPKAQGLQCSIEYNTALYXXQKI
                     TRWIEQFQQLLQEILIHPEQRIKQLPLLTEAQT"
     CDS_motif       complement(269..388)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg438_1_0008"
                     /evalue="1.50E-04"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="ctg438_1"
                     /protein_end="992"
                     /protein_start="952"
                     /score="14.0"
                     /tool="antismash"
                     /translation="KKVSLEGYTHLDFPAEKVLSNFKYKRNLSYYPWFQVVFILL"
     aSDomain        complement(428..1330)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg438_1_Condensation_LCL.1"
                     /domain_subtype="Condensation_LCL"
                     /evalue="4.10E-101"
                     /label="ctg438_1_Condensation_LCL.1"
                     /locus_tag="ctg438_1"
                     /protein_end="939"
                     /protein_start="638"
                     /score="329.6"
                     /tool="antismash"
                     /translation="SLPLTVYQERIWLLAQRAEQHPIYNLPMVFRLQGSLNIALLEKAI
                     NQVIKRHESLRTIFAVVNGLPRQQILPELTLKISVVDVITKPLSQAEEEQYIQTLINQE
                     ASHPFNLQADPLIRVKLFQLRTDDFILMITCHHIISDGWSLSVLLNEISLFYTHFIQER
                     QLDLPELTVNYGDFTLWHQQRQQETETSLLNYWTNQLMGALPLLNLPTDHPRPAIQTFK
                     GTIQYFHINQDIKTQIESFSQAHSATLFMVLVAVFQTLLHRYSNQDDIVMGSPIASRNY
                     SSLENLIGCFANIIPLRTHTH"
     aSModule        428..1330
                     /domains="nrpspksdomains_ctg438_1_Condensation_LCL.1"
                     /incomplete
                     /locus_tags="ctg438_1"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(437..526)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg438_1_0007"
                     /evalue="2.00E-11"
                     /label="C5_LCL_267-296"
                     /locus_tag="ctg438_1"
                     /protein_end="936"
                     /protein_start="906"
                     /score="36.3"
                     /tool="antismash"
                     /translation="DIVMGSPIASRNYSSLENLIGCFANIIPLRT"
     CDS_motif       complement(863..928)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg438_1_0006"
                     /evalue="1.50E-10"
                     /label="C3_LCL_132-143"
                     /locus_tag="ctg438_1"
                     /protein_end="794"
                     /protein_start="772"
                     /score="33.5"
                     /tool="antismash"
                     /translation="CHHIISDGWSLSVLLNEISLFYT"
     CDS_motif       complement(1151..1267)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg438_1_0005"
                     /evalue="2.90E-19"
                     /label="C2_LCL_024-062"
                     /locus_tag="ctg438_1"
                     /protein_end="698"
                     /protein_start="659"
                     /score="61.4"
                     /tool="antismash"
                     /translation="PIYNLPMVFRLQGSLNIALLEKAINQVIKRHESLRTIFAV"
     aSDomain        complement(1391..1606)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg438_1_PCP.1"
                     /evalue="5.40E-18"
                     /label="ctg438_1_PCP.1"
                     /locus_tag="ctg438_1"
                     /protein_end="618"
                     /protein_start="546"
                     /score="56.7"
                     /tool="antismash"
                     /translation="EHQIAAIWQEILGFEVGVNETFTDLGGNSLQATRILSRIRDGFGV
                     DIPVSAMLQDCNSSAATVASLAEYVTHR"
     aSModule        1391..3139
                     /complete
                     /domains="nrpspksdomains_ctg438_1_AMP-binding.1"
                     /domains="nrpspksdomains_ctg438_1_PCP.1"
                     /locus_tags="ctg438_1"
                     /monomer_pairings="val -> val"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(1907..1972)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg438_1_0004"
                     /evalue="7.80E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg438_1"
                     /protein_end="446"
                     /protein_start="424"
                     /score="37.1"
                     /tool="antismash"
                     /translation="FLGRFDFQVKIRGFRVELAEIEA"
     aSDomain        complement(1937..3139)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg438_1_AMP-binding.1"
                     /evalue="1.60E-112"
                     /label="ctg438_1_AMP-binding.1"
                     /locus_tag="ctg438_1"
                     /protein_end="436"
                     /protein_start="35"
                     /score="367.8"
                     /specificity="consensus: val"
                     /tool="antismash"
                     /translation="FQRQAAKSPDAIAIAYQNQQLTYQELEQQSNQLAQYLQSLGVTTE
                     TLVSFYLERSPELIITILAILKAGGAYLPLEPSTPPQRLNTILADAQAPILITQKNKLT
                     ALPKLPDSLHLLCLDDYFNSTTSSPPVPPTHHVNSHNLAYVMYTSGSTGKPKGVCVPHR
                     GVVRLVKNTNYAHFGADEIVLQLASIAFDAATFEIWGALLNGGKLVLMPAKIPSLPEIA
                     TAIKEHKITTLWLTAGLFHLMVEEQIESLKPLRQLLAGGDVLSIPHVKKVLTKLPNCQL
                     INGYGPTENTTFTCCHQITIEDTTKPSIPIGRPIANTQVYILNPDLQPVPIGHPGELYI
                     GGDGLARGYLNQPDLTQERFIANPFSQESNSRLYKTGDKVRWREDGVIEFLGRFDFQVK
                     IRG"
     CDS_motif       complement(2060..2149)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg438_1_0003"
                     /evalue="4.80E-18"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg438_1"
                     /protein_end="395"
                     /protein_start="365"
                     /score="57.2"
                     /tool="antismash"
                     /translation="PIGHPGELYIGGDGLARGYLNQPDLTQERFI"
     CDS_motif       complement(2654..2713)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg438_1_0002"
                     /evalue="2.50E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg438_1"
                     /protein_end="197"
                     /protein_start="177"
                     /score="32.2"
                     /tool="antismash"
                     /translation="AYVMYTSGSTGKPKGVCVPHR"
     CDS_motif       complement(2915..2953)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg438_1_0001"
                     /evalue="3.70E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg438_1"
                     /protein_end="110"
                     /protein_start="97"
                     /score="16.9"
                     /tool="antismash"
                     /translation="LAILKAGGAYLPLE"
     CDS             complement(3479..4432)
                     /locus_tag="ctg438_2"
                     /transl_table=11
                     /translation="TQDGVSVDVSAFSQKWGTWKNAYLGAYSGGLGVTNRDEWKLNHRV
                     DNSGSTDYILFEFDQDVTVDKAFLDYVGWDSDMSIWIGDRDGADISHLNDSLLDSFTKE
                     NNFTHHGRDRWADFNNSELSGDTVVISAYTHGSNDSFKLKKLDVSVTETTIGEYQNVAT
                     VQASTVSDSDTSGYTNPTSTNSTADYVEIAGTSGVDHITGTHANEHIIGYGDSDILTGG
                     GGADQFVFTSLHDRRDKITDFELGTDVIDISQVLDEIGYAGNDAIGDGYVQLGSNSYGA
                     VVSVDQDGFGDDYDPVALVEMANANVNSLSASHFIF"
ORIGIN
        1 tggtttgagc ttccgttaac agaggcaatt gtttaatccg ttgttcggga tggataagaa
       61 tttcctggag taattgttga aactgttcaa tccagcgagt aattttttga tngcnataaa
      121 gagccgtatt atattcaatc gagcattgta atccttgggc ttttggctca actaaaaaga
      181 ccaaatcgca aatcgccgct cctttattaa actttttctc agtaacttta agtcccggta
      241 attcaaaatc agtctgagga acattgagca aaatgaaaac cacctgaaac cagggataat
      301 aactcagatt tcgtttatat ttaaagttcg ataacacttt ttctgccgga aaatctagat
      361 gggtatatcc ctcaagtgat acctttttaa cctgtgccag aaattcnaga aaagatggat
      421 tgtngtgggt atgagttctt aatggaataa tattggcaaa gcaaccaatt aaattttcta
      481 agctgctata gttgcggcta gcaatcggag agcccatcac aatgtcgtct tgattactat
      541 aacggtggag taaagtttgg aatacagcga ctagcaccat aaataaggta gcgctatgag
      601 cttgactgaa ggactcaatt tgggttttaa tgtcttgatt aatgtgaaaa tattgaatcg
      661 ttcctttaaa ggtttgtatn gcaggacgag gatgatctgt aggtaaattt aacaaaggca
      721 aagcccccat aagttgattc gtccaatagt tgaggaggga ggtttccgtt tcttgctgtc
      781 gttgttgatg ccatagggtg aaatcaccat aattcaccgt cagttcgggc aagtctaatt
      841 gacgttcttg gataaaatga gtatagaata gcgaaatttc attgagtaat acgctgagtg
      901 accaaccatc actgataatg tgatgacaag ttatcattaa aataaaatca tcggttcgga
      961 gttggaataa tttaacccga atcagaggat cagcttgcaa attaaacggg tggctggctt
     1021 cttgattaat taaggtttga atatattgct cttcctcggc ttgactcaac ggcttcgtga
     1081 ttacatcgac aacagagatt ttaagggtga gttcaggaag aatttgttgt ctgggtaatc
     1141 cattcaccac cgcaaaaata gtgcgtaggg attcgtggcg tttgatcacc tgattaatcg
     1201 ctttttctaa taaagcaata ttcagacttc cctgaagacg aaacaccatg ggtaagttat
     1261 aaatggggtg ttgttcggcg cgttgtgcca ataaccagat tctttcttga taaacggtta
     1321 agggtaaaga atccccatga ggaatcgctt ttactggatt aatgtcgctc acatcctctt
     1381 ggatagcgcg atgcgtcaca tattcagcta aactggcaac agttgccgcc gatgagttac
     1441 aatcttgtag cattgctgat accggaatat ctacgccaaa cccatctcga atccgagaca
     1501 aaatgcgagt cgcttgtaaa gaatttccgc ctaaatcggt aaaggtttca ttaacaccta
     1561 cttcaaagcc taaaatttct tgccatatcg ccgcaatctg atgttctgct gggttacgag
     1621 gctggacaaa ttggcgattt gaccctaaat tccgatgggg aacaggtaac gcttttcgat
     1681 cgacttttcc attaatattc agcgggaatt gttctaacac aataaaggct gatggaatca
     1741 tataactggg cagttttttg agcagaaaag atttgatgtg agtcgaattt aaggtttgat
     1801 gatgatcttc aggaacaaga tacgcgacta aacgcttatc ccccggttga tcttccctgg
     1861 ctaaaaccac aacattccgc acattcggat agtcttgtaa aactgcctca atttctgcta
     1921 attcaacgcg aaatccccga attttaactt ggaaatcaaa tcgtcctaaa aattcaatca
     1981 cgccatcttc tcgccaacgc actttgtctc ctgttttata tagacgagaa tttgactcct
     2041 gactaaaggg attggcaata aaccgttctt gggttaaatc cggttgattc agataacccc
     2101 gggctaatcc atcgccacca atgtataatt ctcctggatg accaatggga acgggttgta
     2161 aatcaggatt gagaatatag acttgggtat tggcaatggg acgtccgata ggaatagagg
     2221 gttttgtggt gtcctctatt gtaatttgat ggcaacaggt aaaggtagtg ttttcggttg
     2281 gtccgtagcc attgattaat tgacaattgg gcaacttagt taagactttt ttgacatggg
     2341 gaatcgataa aacatcacca ccggctaaga gttgccgcaa gggtttcagt gattctattt
     2401 gttcctcgac cattaaatga aataagccag cagttagcca taaagtcgta attttgtgtt
     2461 ctttgatggc tgtagcaatt tctggcaaag atggtatttt cgcgggcatt aaaactagtt
     2521 taccgccatt gagtaaagct ccccaaattt caaaggttgc tgcatcaaag gcaatagaag
     2581 ccagttgtaa tacgatttca tcagcaccaa agtgggcata gttggtattt ttgactagcc
     2641 gaactacccc acgatgaggg acacaaacgc ctttgggttt acccgtggaa ccggatgtgt
     2701 acatcacata agctaaattg tgactattaa cgtgatgggt tggtggaaca ggaggagatg
     2761 atgttgttga attgaaataa tcgtccagac ataggagatg cagggagtct gggagttttg
     2821 gcagagcggt taatttattt ttttgtgtaa ttaaaatagg ggcttgggca tccgctaaga
     2881 ttgtgtttaa ccgctggggt ggggtggagg gttctaaggg taaataagcg ccacctgctt
     2941 tgagaatggc taagattgta ataattaatt ctggagaacg ttctaaataa aagctaacta
     3001 gggtttctgt ggttacgcca agactttgta aatactgggc aagttgatta gattgttgct
     3061 caagttcctg gtaggtaagc tgctgattct ggtacgcgat cgcaatggca tcaggacttt
     3121 ttgctgcttg gcgttgaaat aagtcatgaa tggtagaatt gtaaggatag tccgtttgtg
     3181 tggttgtcca tttttgcagc aatttatggt gtttaaattc cggtagtgag agtggactat
     3241 tcatttttat ttcattgata tagtgcgtta aaactcaagt tttttcgcat ttgtttgaca
     3301 taaataactt gagtttaaac ctggttcgta atagctattg ctttaatttt actcaaaaat
     3361 ggtaggctag tcaatttgat cattccgata acgtttgatc ggaataggta agacaaagca
     3421 ttagccttgc ctcacccatg tcattggttc aggacaagca ttccctatcc cctaggaatt
     3481 agaaaatgaa gtggctagca gacaagctgt tgacattagc atttgccatc tcaactagag
     3541 ctaccggatc ataatcatca ccaaaaccat cttgatcaac gctgacaact gcaccgtagg
     3601 aattggagcc aagttgtaca taaccatcgc cgatcgcatc attgccggca tagccaattt
     3661 catcaaggac ttggctaata tcaataacat cggtaccaag ttcaaagtca gtaatcttat
     3721 cccggcgatc atgcagactg gtgaagacaa attggtcagc gccgccacct ccagttaaga
     3781 tatccgagtc accgtaacca ataatatgct cattggcatg agtaccggtg atatgatcaa
     3841 caccagatgt tccggcaatt tcaacataat cagcagttga gttggtagaa gttggattag
     3901 tgtagccact ggtgtcactg tcgctcaccg tactcgcctg taccgttgcc acattttgat
     3961 actccccaat agtggtttct gtgacagaaa catccagttt tttgagttta aaggagtcat
     4021 tgctgccatg ggtgtaggca gaaattacca ccgtatcccc agataactct gagttattga
     4081 aatcagccca gcgatcgcgt ccatgatggg taaagttatt ttccttggtg aagctatcca
     4141 acaggctgtc atttaagtgt gagatatccg caccatcgcg atcgccaatc cagatggaca
     4201 tatcgctatc ccagccgaca taatccagga aggctttgtc taccgtgaca tcttggtcga
     4261 attcaaacag gatgtaatcg gtactcccgc tattatcaac gcggtgattc aatttccatt
     4321 catcacggtt cgtcacacct aagccaccac tgtatgcacc taaatacgca tttttccagg
     4381 ttccccattt ctgactaaag gcgctgacat caaccgaaac cccatcttga gt
//
