LOCUS       c00139_3300000..        6357 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300000353.a:ElkS_mat_MD6ADRAFT_1003000.
ACCESSION   c00139_3300000..
VERSION     c00139_3300000..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 04:55:41
            Original ID  :: 3300000353.a:ElkS_mat_MD6ADRAFT_1003000
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 6357
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     aSDomain        1..576
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg139_1_nMT.1"
                     /domain_subtype="nMT"
                     /evalue="2.10E-97"
                     /label="ctg139_1_nMT.1"
                     /locus_tag="ctg139_1"
                     /protein_end="192"
                     /protein_start="0"
                     /score="317.7"
                     /tool="antismash"
                     /translation="EIGCGTGLLLSRIAPHTQEYWGADYASAALQQVDKICQRQGLQQV
                     RLLHQMADDFTNIREGKFDTVVLNSVVQYFPSFEYLLQVLDGAMATIGESGTIFVGDVR
                     SLPLLEAYHAAVQLSRLPGDTTVEQWQQQVNQSVTAEEELVIDPSFFIALSTRFPQITS
                     VEIEPKRGYAQNNELTQFRYDVTLHVGGEV"
     aSModule        1..1401
                     /domains="nrpspksdomains_ctg139_1_nMT.1"
                     /domains="nrpspksdomains_ctg139_1_PCP.1"
                     /incomplete
                     /locus_tags="ctg139_1"
                     /tool="antismash"
                     /type="unknown"
     CDS             1..1476
                     /NRPS_PKS="Domain: nMT (0-192). E-value: 2.1e-97. Score:
                     317.7. Matches aSDomain: nrpspksdomains_ctg139_1_nMT.1"
                     /NRPS_PKS="Domain: PCP (400-467). E-value: 6.9e-28. Score:
                     88.4. Matches aSDomain: nrpspksdomains_ctg139_1_PCP.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg139_1"
                     /sec_met_domain="PP-binding (E-value: 2.8e-20, bitscore:
                     60.4, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="EIGCGTGLLLSRIAPHTQEYWGADYASAALQQVDKICQRQGLQQV
                     RLLHQMADDFTNIREGKFDTVVLNSVVQYFPSFEYLLQVLDGAMATIGESGTIFVGDVR
                     SLPLLEAYHAAVQLSRLPGDTTVEQWQQQVNQSVTAEEELVIDPSFFIALSTRFPQITS
                     VEIEPKRGYAQNNELTQFRYDVTLHVGGEVPTPVETWLNWQLDSLSIAQVETQLKIEQP
                     EVLGIRGVPNQRVQQALQIWQWLEAPPGVETINQLRQLLTQQPGVGINPEQFWQLGENL
                     GYQVHLSWWESSTDGGYDLVFYRNSFSPIEFWHPETVTAKPWSDYTNNPLYGKLVQKLV
                     PQVRQFVQQKLPNYMMPQAFVLLSALPLTPNGKVDRKALPTPDTATRNLSTGLALPRNP
                     IEAKLVQIWSEVLGIEHIGIKDNFFELGGHSLLATQVISRLSNLFEVELSLQNFLEYPT
                     VASLAETIQVLSTVQNGQPSVTELSEDYEEGEL"
     protocluster    1..6357
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1697:5912](+)"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1698..5912
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..6357
                     /SMILES="NC(C(C)CC)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..6357
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="(cds(Condensation and (AMP-binding or A-OX)) or
                     (Condensation and AMP-binding))"
                     /tool="antismash"
     aSDomain        1201..1401
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg139_1_PCP.1"
                     /evalue="6.90E-28"
                     /label="ctg139_1_PCP.1"
                     /locus_tag="ctg139_1"
                     /protein_end="467"
                     /protein_start="400"
                     /score="88.4"
                     /tool="antismash"
                     /translation="EAKLVQIWSEVLGIEHIGIKDNFFELGGHSLLATQVISRLSNLFE
                     VELSLQNFLEYPTVASLAETIQV"
     CDS_motif       1264..1293
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg139_1_0001"
                     /evalue="2.90E-03"
                     /label="PCP_mC"
                     /locus_tag="ctg139_1"
                     /protein_end="431"
                     /protein_start="421"
                     /score="11.0"
                     /tool="antismash"
                     /translation="NFFELGGHSLL"
     CDS             1698..5912
                     /NRPS_PKS="Domain: Condensation_LCL (72-373). E-value:
                     3.7e-118. Score: 385.6. Matches aSDomain:
                     nrpspksdomains_ctg139_2_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (539-939). E-value:
                     9.9e-116. Score: 378.4. Matches aSDomain:
                     nrpspksdomains_ctg139_2_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (1047-1115). E-value: 1.4e-24.
                     Score: 77.8. Matches aSDomain:
                     nrpspksdomains_ctg139_2_PCP.1"
                     /NRPS_PKS="Domain: Thioesterase (1135-1396). E-value:
                     7.6e-34. Score: 109.8. Matches aSDomain:
                     nrpspksdomains_ctg139_2_Thioesterase.1"
                     /NRPS_PKS="type: NRPS"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     454.5; E-value: 7.6e-138)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg139_2"
                     /sec_met_domain="Condensation (E-value: 4.7e-81, bitscore:
                     259.8, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 6.2e-125, bitscore:
                     404.6, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 3.7e-18, bitscore:
                     53.7, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVVEFLSYLNRLDIKLWLEEEKLKYHAPKGAMTPEIKQEIGTRK
                     SEIIAFFQQANATSRATESAIMPMSRDNRIPLSFAQQRLWFLHQLSPDSQSYNMLEALR
                     LKGSLDVVALEKSLSELVRRHEILRTTFPMVDGEAIQQIADPTPLTLPIQDLQGLSTEE
                     QTAQIEQLVKSLAAESFDLASEPPLQFTLLKLSAHEQVLLLKMHHIIYDGWSMNIFFSE
                     LSFLYRAFSQGLPSPLPELPLQYADFALWQRQWLTGDVLERQLNYWQNQLADAPPVVEL
                     PTDYPRPPVQTFQGAVECLRLNQELTQRLKQLSQDSKTTLFMTLLAAFFVTLSRHSNQL
                     DLVVGSPIANRNNQSLEGLIGFFANTLALRGNLSGNPSFKDFLAQVKQTTLSAYAHQDL
                     PFEMLVERLQPERDLSRNPLVQVMFSLQNASPSQGGLSGLAMESLPLPVDVRARFDLEV
                     IIWEMSEGLEGVWSYNSDLFDGATITRMGQHFQTVLEAVVANPEVRVAEIPLLSPAERD
                     QLLVEWNNTQTDYPQDKCIHQLFEEQVEHNGDAIALVYDDQYLTYRELNGRANQLARYL
                     RSLGVEADRLVGLCVERSLDMVVGLLGILKAGGAYLPLDPEYPQERLSFMLEDTQVKVL
                     LTQAKFRDSLPPHQAHIVCLDTDWQTINQANPDNLNNTVSAENLAYVIYTSGSTGTPKG
                     VVVTQRAVNRLVLNTNYIQLTANDCIAQAATIAFDAATFEIWGALLNGAKLVFINQSAL
                     LSPEEFAVNLSSQGVSVLFLTTALFNQLASFVPQAFSSLKYLLFGGEAVDPRWVQEVLD
                     KGAPQQLFHVYGPTENTTFSSWYLVENLPTAATTIPIGRPIANTQIYILDEYLQPVPVG
                     VPGELHIGGAGLAKGYLNRPELTIEKFIPNPFSADSDSRLYKTGDLVRYLKDGNIEFLG
                     RIDNQVKIRGFRIELGEIEAVLSQHEDVQIACVMLREDTPGEKRIVAYVVPQPKVTVTT
                     STLRQFLTHKLPGYMIPSAFMILDSLPLTPNGKVDRRALKAPSNSSDSDTFVQARNQLE
                     LQLVQLWSKVLKVDKIGVQDNFFELGGHSLLASYLITQVKQQLGKDIPLITLFQNPTIE
                     QLATIIQTGSDHSTPSCLVAIQPQGSKPPFFCVPGAGGRPFYFYHLGRYLGEDQPFYSF
                     ENNLSQESGSITRIEDMASIYIEAMQAVQPQGPYFLGGHSYGGNVAFEMGKQLYKQGQE
                     VALLAIIDSSAPTYKDKQMLIDYINWDHARWLAEVSKGIEVYLDKDVDISYETLQPLTV
                     EEQLNYVLHYFKMANMLPPNAETTQLTNIVQAYKTSCLCLVDYEPQEMYPGKLTIIRAN
                     EDLPDDPNRELASDNEDFSLGWSEFCTEPVDIHFVLGNHITITAEPHVQVLAEQLKACI
                     DL"
     aSDomain        1914..2816
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg139_2_Condensation_LCL.1"
                     /domain_subtype="Condensation_LCL"
                     /evalue="3.70E-118"
                     /label="ctg139_2_Condensation_LCL.1"
                     /locus_tag="ctg139_2"
                     /protein_end="373"
                     /protein_start="72"
                     /score="385.6"
                     /tool="antismash"
                     /translation="NRIPLSFAQQRLWFLHQLSPDSQSYNMLEALRLKGSLDVVALEKS
                     LSELVRRHEILRTTFPMVDGEAIQQIADPTPLTLPIQDLQGLSTEEQTAQIEQLVKSLA
                     AESFDLASEPPLQFTLLKLSAHEQVLLLKMHHIIYDGWSMNIFFSELSFLYRAFSQGLP
                     SPLPELPLQYADFALWQRQWLTGDVLERQLNYWQNQLADAPPVVELPTDYPRPPVQTFQ
                     GAVECLRLNQELTQRLKQLSQDSKTTLFMTLLAAFFVTLSRHSNQLDLVVGSPIANRNN
                     QSLEGLIGFFANTLALRGNLS"
     aSModule        1914..5885
                     /complete
                     /domains="nrpspksdomains_ctg139_2_Condensation_LCL.1"
                     /domains="nrpspksdomains_ctg139_2_AMP-binding.1"
                     /domains="nrpspksdomains_ctg139_2_PCP.1"
                     /domains="nrpspksdomains_ctg139_2_Thioesterase.1"
                     /final_module
                     /locus_tags="ctg139_2"
                     /monomer_pairings="ile -> ile"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       1929..1961
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg139_2_0001"
                     /evalue="2.10E-03"
                     /label="C1_LCL_004-017"
                     /locus_tag="ctg139_2"
                     /protein_end="88"
                     /protein_start="77"
                     /score="10.6"
                     /tool="antismash"
                     /translation="SFAQQRLWFLHQ"
     CDS_motif       1983..2096
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg139_2_0002"
                     /evalue="1.50E-18"
                     /label="C2_LCL_024-062"
                     /locus_tag="ctg139_2"
                     /protein_end="133"
                     /protein_start="95"
                     /score="59.2"
                     /tool="antismash"
                     /translation="SYNMLEALRLKGSLDVVALEKSLSELVRRHEILRTTFPM"
     CDS_motif       2313..2378
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg139_2_0003"
                     /evalue="8.40E-11"
                     /label="C3_LCL_132-143"
                     /locus_tag="ctg139_2"
                     /protein_end="227"
                     /protein_start="205"
                     /score="34.3"
                     /tool="antismash"
                     /translation="MHHIIYDGWSMNIFFSELSFLYR"
     CDS_motif       2427..2465
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg139_2_0004"
                     /evalue="3.00E-06"
                     /label="C4_LCL_164-176"
                     /locus_tag="ctg139_2"
                     /protein_end="256"
                     /protein_start="243"
                     /score="19.6"
                     /tool="antismash"
                     /translation="QYADFALWQRQWLT"
     CDS_motif       2718..2807
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg139_2_0005"
                     /evalue="7.00E-16"
                     /label="C5_LCL_267-296"
                     /locus_tag="ctg139_2"
                     /protein_end="370"
                     /protein_start="340"
                     /score="50.5"
                     /tool="antismash"
                     /translation="DLVVGSPIANRNNQSLEGLIGFFANTLALRG"
     CDS_motif       2856..2975
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg139_2_0006"
                     /evalue="1.90E-26"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="ctg139_2"
                     /protein_end="426"
                     /protein_start="386"
                     /score="84.6"
                     /tool="antismash"
                     /translation="KQTTLSAYAHQDLPFEMLVERLQPERDLSRNPLVQVMFSLQ"
     aSDomain        3315..4514
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg139_2_AMP-binding.1"
                     /evalue="9.90E-116"
                     /label="ctg139_2_AMP-binding.1"
                     /locus_tag="ctg139_2"
                     /protein_end="939"
                     /protein_start="539"
                     /score="378.4"
                     /specificity="consensus: ile"
                     /tool="antismash"
                     /translation="FEEQVEHNGDAIALVYDDQYLTYRELNGRANQLARYLRSLGVEAD
                     RLVGLCVERSLDMVVGLLGILKAGGAYLPLDPEYPQERLSFMLEDTQVKVLLTQAKFRD
                     SLPPHQAHIVCLDTDWQTINQANPDNLNNTVSAENLAYVIYTSGSTGTPKGVVVTQRAV
                     NRLVLNTNYIQLTANDCIAQAATIAFDAATFEIWGALLNGAKLVFINQSALLSPEEFAV
                     NLSSQGVSVLFLTTALFNQLASFVPQAFSSLKYLLFGGEAVDPRWVQEVLDKGAPQQLF
                     HVYGPTENTTFSSWYLVENLPTAATTIPIGRPIANTQIYILDEYLQPVPVGVPGELHIG
                     GAGLAKGYLNRPELTIEKFIPNPFSADSDSRLYKTGDLVRYLKDGNIEFLGRIDNQVKI
                     RG"
     CDS_motif       3501..3542
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg139_2_0007"
                     /evalue="1.40E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg139_2"
                     /protein_end="615"
                     /protein_start="601"
                     /score="18.2"
                     /tool="antismash"
                     /translation="LGILKAGGAYLPLDP"
     CDS_motif       3735..3791
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg139_2_0008"
                     /evalue="4.50E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg139_2"
                     /protein_end="698"
                     /protein_start="679"
                     /score="31.4"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGTPKGVVVTQ"
     CDS_motif       4302..4391
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg139_2_0009"
                     /evalue="8.60E-17"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg139_2"
                     /protein_end="898"
                     /protein_start="868"
                     /score="53.2"
                     /tool="antismash"
                     /translation="PVGVPGELHIGGAGLAKGYLNRPELTIEKFI"
     CDS_motif       4479..4544
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg139_2_0010"
                     /evalue="1.20E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg139_2"
                     /protein_end="949"
                     /protein_start="927"
                     /score="39.6"
                     /tool="antismash"
                     /translation="FLGRIDNQVKIRGFRIELGEIEA"
     aSDomain        4839..5042
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg139_2_PCP.1"
                     /evalue="1.40E-24"
                     /label="ctg139_2_PCP.1"
                     /locus_tag="ctg139_2"
                     /protein_end="1115"
                     /protein_start="1047"
                     /score="77.8"
                     /tool="antismash"
                     /translation="ELQLVQLWSKVLKVDKIGVQDNFFELGGHSLLASYLITQVKQQLG
                     KDIPLITLFQNPTIEQLATIIQTG"
     aSDomain        5103..5885
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg139_2_Thioesterase.1"
                     /evalue="7.60E-34"
                     /label="ctg139_2_Thioesterase.1"
                     /locus_tag="ctg139_2"
                     /protein_end="1396"
                     /protein_start="1135"
                     /score="109.8"
                     /tool="antismash"
                     /translation="PFFCVPGAGGRPFYFYHLGRYLGEDQPFYSFENNLSQESGSITRI
                     EDMASIYIEAMQAVQPQGPYFLGGHSYGGNVAFEMGKQLYKQGQEVALLAIIDSSAPTY
                     KDKQMLIDYINWDHARWLAEVSKGIEVYLDKDVDISYETLQPLTVEEQLNYVLHYFKMA
                     NMLPPNAETTQLTNIVQAYKTSCLCLVDYEPQEMYPGKLTIIRANEDLPDDPNRELASD
                     NEDFSLGWSEFCTEPVDIHFVLGNHITITAEPHVQVLAEQ"
     CDS_motif       5280..5354
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg139_2_0011"
                     /evalue="2.70E-13"
                     /label="NRPS-te1"
                     /locus_tag="ctg139_2"
                     /protein_end="1219"
                     /protein_start="1194"
                     /score="42.2"
                     /tool="antismash"
                     /translation="QPQGPYFLGGHSYGGNVAFEMGKQLY"
     CDS             5960..6355
                     /NRPS_PKS="Domain: oMT (17-132). E-value: 1.2e-45. Score:
                     147.3. Matches aSDomain: nrpspksdomains_ctg139_3_oMT.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089:methyltransferase (Score: 117.4; E-value:
                     1.2e-35)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg139_3"
                     /transl_table=11
                     /translation="MDKTEFITQFDQLILNSETRSIYGQHEFFNVGYWLPETQNQEEAC
                     FNLMEKLLEFIPEKTGKILDVGCGLGATTNYLLKYYSPADVVGINISSQQLERCRVNVP
                     NGNFMEMDAVQMKFEENQFDQIICVEAA"
     aSDomain        6011..6355
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg139_3_oMT.1"
                     /domain_subtype="oMT"
                     /evalue="1.20E-45"
                     /label="ctg139_3_oMT.1"
                     /locus_tag="ctg139_3"
                     /protein_end="132"
                     /protein_start="17"
                     /score="147.3"
                     /tool="antismash"
                     /translation="ETRSIYGQHEFFNVGYWLPETQNQEEACFNLMEKLLEFIPEKTGK
                     ILDVGCGLGATTNYLLKYYSPADVVGINISSQQLERCRVNVPNGNFMEMDAVQMKFEEN
                     QFDQIICVEAA"
     aSModule        6011..6355
                     /domains="nrpspksdomains_ctg139_3_oMT.1"
                     /incomplete
                     /locus_tags="ctg139_3"
                     /tool="antismash"
                     /type="unknown"
ORIGIN
        1 gaaattggtt gtggcaccgg tttacttctg tctcggattg cgcctcacac tcaggagtat
       61 tggggcgccg attatgccag tgctgcttta caacaggttg ataagatttg tcaacgtcag
      121 ggtttacaac aggtgcgact cctgcaccaa atggcggatg attttaccaa catcagggaa
      181 ggcaaattcg acacggtagt tttgaattca gttgtccaat atttccccag ttttgagtat
      241 ttgctacagg ttttagatgg ggcaatggca acgattggtg aaagcggtac tatctttgtc
      301 ggggatgtac ggagtctgcc cttactcgaa gcctatcatg ccgccgtgca gttatctcga
      361 ttaccggggg ataccacggt tgagcaatgg caacaacagg ttaatcaaag tgttacggct
      421 gaagaagaat tggtgattga tcccagtttc ttcatcgctc tttccactcg ttttcctcag
      481 attacttcgg tagagattga gccgaaacgg ggctatgccc agaataatga gttaactcaa
      541 ttccgttatg atgtcaccct tcatgtcggc ggtgaggttc ccaccccggt tgagacttgg
      601 ttgaactggc aattagattc cctttcaatc gcacaagttg aaactcaact caaaatcgag
      661 cagccagaag ttttagggat tcgtggtgta cccaaccaac gggtacaaca agccttacag
      721 atttggcaat ggttggaagc accgccaggg gtggagacaa tcaaccaact gcggcaatta
      781 ctcacacaac agcccggagt gggaattaat cccgaacagt tttggcaact gggtgaaaat
      841 ctgggctacc aggtgcattt aagttggtgg gagagttcca ccgatggggg ttatgatctg
      901 gtgttctatc gtaatagttt ttctcccatt gagttttggc acccagaaac ggtaacagct
      961 aaaccctgga gtgactatac caacaatccc ctgtatggta agttagtcca gaaactggtg
     1021 ccacaggtgc gtcagtttgt gcaacaaaag ttgcctaatt atatgatgcc ccaggctttt
     1081 gtgctgcttt ctgctttgcc tttgacaccg aatggtaagg ttgaccgtaa agccttaccc
     1141 actccagata cggctacccg gaatctgtct actggcttgg ctttaccccg caacccgatt
     1201 gaggctaaac tggttcaaat ctggagtgag gtgttgggga ttgaacacat cggcattaag
     1261 gataatttct ttgaacttgg gggacattcc ttgctggcga ctcaagtgat ttctcggtta
     1321 agtaatttgt ttgaggtgga attgtcttta caaaattttc tggagtatcc cacggtggcg
     1381 agtttggctg agacgattca ggtactttcc acggtacaaa acggtcaacc ttctgtcact
     1441 gaactatcag aggattatga agaaggtgaa ttgtaatata acatttctca tcagaaacta
     1501 gcagaagtga tttttcgatt agcccgagaa gatacccagc cagagaggtt aaccaaaatt
     1561 aactcgacct catggttgaa tgggtgggcg attagtctag atgccagcaa atgggacgct
     1621 gatggacttt ttgaacccaa aagtgaaccc cgcaatttag accggattca aaaccaaatt
     1681 tgggaggcaa ttggcagatg aaagtcgtgg agtttttgtc ttacttaaac cgtttagata
     1741 tcaaactttg gctagaggaa gagaaactca agtatcatgc gcccaagggg gcaatgacac
     1801 cggaaatcaa gcaagaaatc ggcacgagaa aatcggaaat cattgccttt ttccagcaag
     1861 ccaatgccac ctccagagcg actgaatcag cgattatgcc gatgtcacgg gataatcgga
     1921 ttcctctatc ttttgcccag caacgactct ggtttctgca ccaactctcg cctgacagtc
     1981 agtcttacaa tatgctggag gcgctgcggt taaagggttc actcgatgtt gttgccctag
     2041 aaaaaagtct cagtgaactg gttcgccgtc atgaaattct cagaaccacg tttcccatgg
     2101 tagacggaga agccattcaa cagattgctg accctactcc tttaacatta cccatccagg
     2161 atttgcaggg gttgtctact gaggaacaaa cggctcaaat tgaacaactg gtgaagtctc
     2221 tggcggctga gtcctttgat ttggcaagtg aacccccact acaatttacg ttgctcaaac
     2281 tgagtgccca cgaacaggta cttctgttga agatgcacca tattatctac gatggttggt
     2341 caatgaatat cttcttcagt gagttgtctt ttctctatag agccttctct caaggactcc
     2401 cctcccctct tccagaatta ccgctccaat atgctgattt tgccctatgg caacgtcagt
     2461 ggctaaccgg agacgttctc gaacggcaac tcaattactg gcagaatcag ttagctgatg
     2521 ctcctccagt tgtggaatta ccaacggatt accctcgtcc ccccgttcaa acgtttcaag
     2581 gtgccgttga atgtttgcga ctgaatcagg aattaactca acgcctcaag caactgagcc
     2641 aggattcaaa aacgacgttg tttatgacgc tgctggcggc tttttttgtc accctttctc
     2701 gtcatagtaa tcagttagat ttagttgttg gctctcccat tgccaatcgc aataaccaaa
     2761 gcctagaggg attaatcgga ttttttgcca ataccctagc cttgaggggg aatctctctg
     2821 gcaatcccag cttcaaagat ttcttggctc aagtcaagca aactaccctg tcagcctatg
     2881 ctcaccaaga cttacccttt gaaatgttgg tcgagaggtt acagccggag cgagatttga
     2941 gtcgaaatcc cctggtacag gtaatgtttt cgctccagaa tgcttcccca tcacaagggg
     3001 gtttgtcagg tttagccatg gagagtctgc ctttgcctgt tgatgtcaga gctagatttg
     3061 acctggaagt gattatttgg gagatgtcag aggggttaga gggcgtttgg tcctacaaca
     3121 gcgatttatt tgatggggct accattactc gcatgggtca acattttcaa actgtactcg
     3181 aggctgttgt agccaatccc gaagtacgag tggctgaaat acccctgtta agtccagccg
     3241 aacgggatca gttgttagtg gagtggaaca acactcaaac ggactatcct caggataaat
     3301 gtatccatca gttatttgag gaacaagtag aacacaacgg tgatgcgatc gcactcgtgt
     3361 atgacgatca atacctaact taccgtgaat taaatggtcg tgccaatcaa ttagcccgct
     3421 atttacgttc cttgggtgta gaagctgata ggctggtggg attatgtgtc gaacgttcct
     3481 tagacatggt ggtgggactg ttgggcattc tcaaagcagg tggagcctac ctgccacttg
     3541 accctgagta tccccaagaa cgcttaagct tcatgctaga agacactcag gtgaaagtgt
     3601 tgttaactca agccaaattc cgagactccc tacccccaca tcaagcacat atcgtctgtt
     3661 tggatactga ctggcaaacg attaaccaag ctaatcccga taatctcaac aacacagtca
     3721 gtgctgaaaa tttagcttat gtaatttata cttctggttc tactggaaca cccaaaggag
     3781 tcgtcgtcac tcagcgggct gtcaatcgac tggtgttaaa caccaattat atccagttaa
     3841 cggcaaatga ttgtattgct caagctgcaa ctattgcttt tgatgctgcc acctttgaaa
     3901 tttggggagc gctactcaac ggagccaagt tggtgttcat caatcaatcg gcattgcttt
     3961 cccctgaaga atttgctgtc aatctaagtt ctcaaggagt cagcgtttta ttcttaacta
     4021 cagctttatt caatcagtta gccagctttg tcccccaagc atttagttct ctcaaatatc
     4081 tactctttgg tggggaagcc gttgacccca gatgggtaca agaagtttta gacaaaggcg
     4141 ctccacagca gctattccat gtttatggac caacagagaa tacgactttt tcttcttggt
     4201 atttggtaga aaacttaccc acagcagcta caactattcc cattggtcgt ccgattgcga
     4261 atacacaaat ttatatccta gacgagtatc tgcaacctgt ccctgtgggc gtaccgggag
     4321 aattacatat tgggggtgca ggattagcaa aaggctatct caaccgccct gagttaacaa
     4381 tagaaaaatt catccctaac ccgtttagcg ccgattcaga ttctcgcctc tataaaactg
     4441 gagatttagt ccgttactta aaagatggca atattgaatt cttaggacgc attgataatc
     4501 aagttaaaat ccggggtttc cgcattgagt taggggaaat agaagcggta ctgagccagc
     4561 atgaagatgt acaaattgct tgtgtcatgc ttcgggaaga tactccaggg gaaaagcgta
     4621 ttgttgctta tgtcgtgccg caacccaaag taacagtcac aaccagtaca ctgcgtcagt
     4681 tcctgaccca taaactcccc ggttacatga tcccatcggc gtttatgatt ctggactctt
     4741 tacccctcac cccgaatggc aaagtagacc gccgcgcctt aaaagcaccg tctaacagta
     4801 gtgactcgga tacatttgtt caagcacgta accaattaga attgcaactg gtgcaacttt
     4861 ggtcaaaggt gctgaaagtt gacaaaattg gggtacaaga taactttttt gaactcgggg
     4921 gtcattccct gctagcctcc tacttaatca ctcaagttaa gcagcagttg ggcaaagata
     4981 ttcctttaat cacgctgttt caaaacccga ccattgaaca gttggcgaca atcattcaaa
     5041 ctggatcaga tcactctact ccgtcttgtt tagtggcgat tcaaccccag gggtcaaaac
     5101 cacccttctt ctgtgttccc ggtgcgggag gtagaccgtt ttacttctat cacttaggac
     5161 gttatttagg agaagatcaa ccgttctaca gttttgaaaa caatctgtct caggaatcag
     5221 ggtcgattac tcgaattgag gatatggcta gtatttatat tgaagccatg caagctgttc
     5281 agccccaagg accctatttt ttaggcggac attcctatgg gggaaatgtt gcgtttgaaa
     5341 tgggtaaaca gttgtataaa cagggacagg aggtagcttt actggcaatc attgattctt
     5401 cagcgccaac gtataaagat aagcaaatgc tgattgatta tattaactgg gatcacgcca
     5461 ggtggctggc tgaggtgagc aagggcatag aagtttattt agataaggat gtcgatattt
     5521 cctacgaaac tctccagccc ttaacagtgg aggagcaact caactacgtt ttacactatt
     5581 tcaaaatggc taatatgcta cctccgaatg cagaaacaac ccagctaacc aatatcgtac
     5641 aagcttataa aactagctgt ttatgtctgg ttgattatga accccaagag atgtatcctg
     5701 gtaaactgac gattatacgc gccaatgagg atctgccgga tgatccgaat cgtgagttgg
     5761 catctgacaa tgaagatttt tccttgggtt ggagcgagtt ttgtacggaa cctgtggata
     5821 tccattttgt gttgggaaat catatcacaa ttacggcgga acctcatgtt caggttttag
     5881 ccgaacagtt aaaagcttgc attgatttgt agagacgttg catgcaacgt ctctacaagt
     5941 taaaaacctg gtgataaaaa tggataaaac cgaattcatt acacaatttg atcagttaat
     6001 tctaaattct gaaaccagaa gcatatatgg tcaacatgag ttttttaatg tcggctattg
     6061 gttgccagag actcagaatc aagaggaagc ctgttttaac ctgatggaaa aactgttaga
     6121 atttattcca gagaaaacag gaaaaatcct agatgtgggc tgcgggttag gcgcgacgac
     6181 caattattta ctgaaatact actcccctgc tgatgtagtg ggcatcaata tttccagcca
     6241 acaacttgaa agatgtcgag tcaatgtacc aaacggcaac ttcatggaaa tggatgctgt
     6301 ccagatgaag tttgaggaga atcaatttga tcagatcatc tgtgttgaag ctgcctt
//
