LOCUS       c00329_3300000..        4622 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300000353.a:ElkS_mat_MD6ADRAFT_1004726.
ACCESSION   c00329_3300000..
VERSION     c00329_3300000..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 04:55:41
            Original ID  :: 3300000353.a:ElkS_mat_MD6ADRAFT_1004726
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 4622
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..4622
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2:3029](-)"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(3..3029)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
     protocluster    1..4622
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3091:4621](-)"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      complement(3092..4621)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="2"
     cand_cluster    1..4622
                     /SMILES="NC(CS)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /kind="neighbouring"
                     /product="T1PKS"
                     /product="NRPS-like"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     region          1..4622
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T1PKS"
                     /product="NRPS-like"
                     /region_number="1"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX))"
                     /tool="antismash"
     CDS             complement(3..3029)
                     /NRPS_PKS="Domain: PKS_KS(Hybrid-KS) (9-435). E-value:
                     7.6e-170. Score: 557.1. Matches aSDomain:
                     nrpspksdomains_ctg329_1_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (543-835). E-value: 2.7e-108.
                     Score: 353.5. Matches aSDomain:
                     nrpspksdomains_ctg329_1_PKS_AT.1"
                     /NRPS_PKS="type: PKS-like protein"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     hyb_KS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1093:Beta-ketoacyl synthase (Score: 82; E-value:
                     5.8e-25)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg329_1"
                     /sec_met_domain="PKS_AT (E-value: 1.1e-109, bitscore:
                     353.5, seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="hyb_KS (E-value: 4.2e-178, bitscore:
                     579.6, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSEPNGLEIAIIGISGRFPKSHTIDQFWENLQNGVELITEFPAV
                     QQNSQVTSTGHQPARQTIKSGSILEDVEQFDASFFGFNPREAEAMDPQHRLFLECAWEA
                     LENAGYDTEREERPIGVYAGVGMSTYSFHNLYPNRELMESRGFLQTLVGIDKDYVPTRV
                     SYKLNLKGPSVSVGTACSSSLVAVHLACQSLLSGECDMALAAGVSVKVPQNELTLSPEE
                     IVSPDGHCRAFDSKANGTIAGNGIGVVVLKRLEDALADGDYIYTVIKGSAINNDGALKV
                     GYTAPSEEGQARVIRAAQLMAEVEPDTISYMETHGTGTPLGDPIEIAAMTRAFRDTTDK
                     KGYCAIGSVKTNVGHLDAAAGITGLIKTALALHHQVLPPSLNFETPNPQIDFANSPFYV
                     NTHCSEWKRNGTPRRAGVSSFGFGGTNVHVILEEAPAVEAKVLETTDTLTGQQERQSHL
                     LVISAKTASALATATRNLASHLQQHPDLNLADIAYTLQVGRRRFEHRRMVVAQDLEDAV
                     NALESGNPQRVFSQFQESSDRSIVFLCTGQGAQYVNMGRELYQSEPTFREECDRCFDLL
                     QPHLGIDLRSCLYPAPEDVEQATDQLKQTAITQPVLFAIEYALAKLWMSWGVQPQALIG
                     HSIGEYVAACLAGVFSLEDALALVATRGRLMQQMPSGAMVSVNLSADEVQPFLGEPLAL
                     AASNAPCLSVVSGSVEAVEQLEQQLEAKGIGYRRLHTSHAFHSPMMNPIIGTFTQHLHT
                     VKLNPPQIPFISNVTGTWITAADATDPNYWARHLRQGVRFAEGISELLKDAQAIFLEVG
                     PGRTLSTLTKQQATERVVLSSLRHPQEEQSDVAFILNTLGKLWLEGVQVDWSGFYAHEQ
                     RDLLKAARLRYRIPLPTYPFERQRYWIDPPEESANSRQVTLSKKPNIADWFYVPSWKRS
                     ITSTCKVNGTSVHSSILVFVDECGLGVQLVEHLQQASQDVIIVKVGSGFSQLSDGVYSL
                     NPRQKDDYKALVDALITQDK"
     aSDomain        complement(525..1400)
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg329_1_PKS_AT.1"
                     /evalue="2.70E-108"
                     /label="ctg329_1_PKS_AT.1"
                     /locus_tag="ctg329_1"
                     /protein_end="835"
                     /protein_start="543"
                     /score="353.5"
                     /specificity="Minowa: mal"
                     /specificity="consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /tool="antismash"
                     /translation="CTGQGAQYVNMGRELYQSEPTFREECDRCFDLLQPHLGIDLRSCL
                     YPAPEDVEQATDQLKQTAITQPVLFAIEYALAKLWMSWGVQPQALIGHSIGEYVAACLA
                     GVFSLEDALALVATRGRLMQQMPSGAMVSVNLSADEVQPFLGEPLALAASNAPCLSVVS
                     GSVEAVEQLEQQLEAKGIGYRRLHTSHAFHSPMMNPIIGTFTQHLHTVKLNPPQIPFIS
                     NVTGTWITAADATDPNYWARHLRQGVRFAEGISELLKDAQAIFLEVGPGRTLSTLTKQQ
                     ATERVVLSSLRH"
     aSModule        525..3002
                     /domains="nrpspksdomains_ctg329_1_PKS_KS.1"
                     /domains="nrpspksdomains_ctg329_1_PKS_AT.1"
                     /incomplete
                     /locus_tags="ctg329_1"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       complement(651..686)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg329_1_0008"
                     /evalue="1.30E-04"
                     /label="PKSI-AT-M_m8"
                     /locus_tag="ctg329_1"
                     /protein_end="793"
                     /protein_start="781"
                     /score="15.3"
                     /tool="antismash"
                     /translation="YWARHLRQGVRFA"
     CDS_motif       complement(723..755)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg329_1_0007"
                     /evalue="1.10E-03"
                     /label="PKSI-AT-M_m7"
                     /locus_tag="ctg329_1"
                     /protein_end="769"
                     /protein_start="758"
                     /score="11.5"
                     /tool="antismash"
                     /translation="PQIPFISNVTGT"
     CDS_motif       complement(1029..1151)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg329_1_0006"
                     /evalue="1.70E-29"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="ctg329_1"
                     /protein_end="667"
                     /protein_start="626"
                     /score="94.4"
                     /tool="antismash"
                     /translation="GVQPQALIGHSIGEYVAACLAGVFSLEDALALVATRGRLMQQ"
     CDS_motif       complement(1155..1214)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg329_1_0005"
                     /evalue="8.20E-06"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="ctg329_1"
                     /protein_end="625"
                     /protein_start="605"
                     /score="18.7"
                     /tool="antismash"
                     /translation="AITQPVLFAIEYALAKLWMSW"
     CDS_motif       complement(1353..1397)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg329_1_0004"
                     /evalue="1.90E-06"
                     /label="PKSI-AT-M_m1"
                     /locus_tag="ctg329_1"
                     /protein_end="559"
                     /protein_start="544"
                     /score="20.1"
                     /tool="antismash"
                     /translation="TGQGAQYVNMGRELYQ"
     aSDomain        complement(1725..3002)
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg329_1_PKS_KS.1"
                     /evalue="7.60E-170"
                     /label="ctg329_1_PKS_KS.1"
                     /locus_tag="ctg329_1"
                     /protein_end="435"
                     /protein_start="9"
                     /score="557.1"
                     /tool="antismash"
                     /translation="IAIIGISGRFPKSHTIDQFWENLQNGVELITEFPAVQQNSQVTST
                     GHQPARQTIKSGSILEDVEQFDASFFGFNPREAEAMDPQHRLFLECAWEALENAGYDTE
                     REERPIGVYAGVGMSTYSFHNLYPNRELMESRGFLQTLVGIDKDYVPTRVSYKLNLKGP
                     SVSVGTACSSSLVAVHLACQSLLSGECDMALAAGVSVKVPQNELTLSPEEIVSPDGHCR
                     AFDSKANGTIAGNGIGVVVLKRLEDALADGDYIYTVIKGSAINNDGALKVGYTAPSEEG
                     QARVIRAAQLMAEVEPDTISYMETHGTGTPLGDPIEIAAMTRAFRDTTDKKGYCAIGSV
                     KTNVGHLDAAAGITGLIKTALALHHQVLPPSLNFETPNPQIDFANSPFYVNTHCSEWKR
                     NGTPRRAGVSSFGFGGTNVHVILEEAPA"
     CDS_motif       complement(1947..1991)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg329_1_0003"
                     /evalue="6.10E-04"
                     /label="PKSI-KS_m6"
                     /locus_tag="ctg329_1"
                     /protein_end="361"
                     /protein_start="346"
                     /score="12.2"
                     /tool="antismash"
                     /translation="GSVKTNVGHLDAAAGI"
     CDS_motif       complement(2052..2099)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg329_1_0002"
                     /evalue="3.90E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="ctg329_1"
                     /protein_end="326"
                     /protein_start="310"
                     /score="12.6"
                     /tool="antismash"
                     /translation="YMETHGTGTPLGDPIEI"
     CDS_motif       complement(2472..2519)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg329_1_0001"
                     /evalue="1.50E-05"
                     /label="PKSI-KS_m3"
                     /locus_tag="ctg329_1"
                     /protein_end="186"
                     /protein_start="170"
                     /score="17.1"
                     /tool="antismash"
                     /translation="GPSVSVGTACSSSLVAV"
     CDS             complement(3092..4621)
                     /NRPS_PKS="Domain: AMP-binding (13-290). E-value: 1.2e-75.
                     Score: 246.3. Matches aSDomain:
                     nrpspksdomains_ctg329_2_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (400-471). E-value: 2.1e-18. Score:
                     58.1. Matches aSDomain: nrpspksdomains_ctg329_2_PCP.1"
                     /NRPS_PKS="type: NRPS-like protein"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     260.7; E-value: 3.5e-79)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg329_2"
                     /sec_met_domain="AMP-binding (E-value: 5.9e-94, bitscore:
                     302.0, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 9.5e-13, bitscore:
                     35.8, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="IHRLCIDTEDFTQERKEPLQPIQTPDDLAYVIYTSGSTGLPKGVM
                     ITHRNVVNVVVHTNQRFNISFQDRILALTALNHDLSVYDIFGLLSAGGTIVMPDACGTK
                     DPSHWAELIVREQVTLWNSVPAMMEMLVDYAQGQSVALPESLRLAILGGDWLPVSLPNR
                     LKALVPDIQVLSIGGPTETTIWNIGYLIEQVESNWQSIPYGQPMANSKYYILNEALEDC
                     PAWVPGQMYCAGVQLAKGYWRDTEKTQANFITHPCTGERIYRTGDLGRYCPDGNIEFLG
                     RVDFQIKIRGYRIEAGEIETTLTQHPAVRSAIVTVVGEQPGNQRLVAYILSDQTPTPTP
                     EEINHLLKQKLSDYMLPSAYVFLDEFPLSANGKVDRRALPTQADSLQTIEVSYVAPQTE
                     IEQMITTVWQEVLGVEKVGINDNLFDLGGNSLLVTKIYQKIKDKLPNNEVTCLSVVDLF
                     KLPTIRLLSQHLSPGHSSNRFNQDSIQFKQNLSRGKSRLKQRFDKSRSRPR"
     aSDomain        complement(3209..3421)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg329_2_PCP.1"
                     /evalue="2.10E-18"
                     /label="ctg329_2_PCP.1"
                     /locus_tag="ctg329_2"
                     /protein_end="471"
                     /protein_start="400"
                     /score="58.1"
                     /tool="antismash"
                     /translation="EQMITTVWQEVLGVEKVGINDNLFDLGGNSLLVTKIYQKIKDKLP
                     NNEVTCLSVVDLFKLPTIRLLSQHLSP"
     aSModule        3209..4582
                     /complete
                     /domains="nrpspksdomains_ctg329_2_AMP-binding.1"
                     /domains="nrpspksdomains_ctg329_2_PCP.1"
                     /locus_tags="ctg329_2"
                     /monomer_pairings="cys -> cys"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(3722..3787)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg329_2_0003"
                     /evalue="2.20E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg329_2"
                     /protein_end="300"
                     /protein_start="278"
                     /score="35.7"
                     /tool="antismash"
                     /translation="FLGRVDFQIKIRGYRIEAGEIET"
     aSDomain        complement(3752..4582)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg329_2_AMP-binding.1"
                     /evalue="1.20E-75"
                     /label="ctg329_2_AMP-binding.1"
                     /locus_tag="ctg329_2"
                     /protein_end="290"
                     /protein_start="13"
                     /score="246.3"
                     /specificity="consensus: cys"
                     /tool="antismash"
                     /translation="ERKEPLQPIQTPDDLAYVIYTSGSTGLPKGVMITHRNVVNVVVHT
                     NQRFNISFQDRILALTALNHDLSVYDIFGLLSAGGTIVMPDACGTKDPSHWAELIVREQ
                     VTLWNSVPAMMEMLVDYAQGQSVALPESLRLAILGGDWLPVSLPNRLKALVPDIQVLSI
                     GGPTETTIWNIGYLIEQVESNWQSIPYGQPMANSKYYILNEALEDCPAWVPGQMYCAGV
                     QLAKGYWRDTEKTQANFITHPCTGERIYRTGDLGRYCPDGNIEFLGRVDFQIKIRG"
     CDS_motif       complement(3866..3955)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg329_2_0002"
                     /evalue="1.80E-09"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg329_2"
                     /protein_end="252"
                     /protein_start="222"
                     /score="29.9"
                     /tool="antismash"
                     /translation="PAWVPGQMYCAGVQLAKGYWRDTEKTQANFI"
     CDS_motif       complement(4478..4537)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg329_2_0001"
                     /evalue="3.30E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg329_2"
                     /protein_end="48"
                     /protein_start="28"
                     /score="34.8"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGLPKGVMITHR"
ORIGIN
        1 cgcttatctt gggtgatcag tgcatcaact aatgctttat agtcatcttt ttgccgagga
       61 ttaagactat atacaccatc gcttaattga ctgaatcctg acccaacttt cacgataatg
      121 acatcttgac ttgcctgttg gaggtgttct actagttgga cacccaaacc acactcatca
      181 acaaacacga gtatgctaga gtgaaccgat gtgccgttca ctttacaggt ggaggtaatg
      241 gagcgtttcc acgaaggaac atagaaccaa tcagcaatgt ttggcttttt gctcaacgtt
      301 acctggcgac tattcgctga ttcctctggt gggtcgatcc aatagcgttg gcgttcaaag
      361 gggtaagtgg gtaacgggat gcgatagcga agtcttgctg ctttgagcag atcgcgttgt
      421 tcatgagcat aaaaacccga ccaatcgacc tgaactcctt ctagccagag tttgcctagg
      481 gtattcagta taaatgccac atcggactgt tcctcctggg gatggcgcag ggaagacagc
      541 accactcgtt cagttgcctg ctgtttggtc aaggtgctta acgttcgtcc tggtcccact
      601 tctaagaaaa tggcttgagc atccttgagt aactcgctaa taccttctgc aaaccgcacg
      661 ccttgacgta gatgccttgc ccagtaattg ggatctgtgg cgtctgcggc ggtaatccaa
      721 gtgccagtga cattggaaat aaaggggatt tggggaggat tgagcttgac ggtatgaaga
      781 tgctgggtga acgtcccgat aatggggttc atcatcggcg aatgaaaggc atgggaggta
      841 tgcaagcgac ggtagccgat tccctttgcc tccagttgct gttccagttg ttctactgct
      901 tccactgaac cggaaaccac acttaaacag ggtgcattac tggcagccag agcgagtggt
      961 tcacctaaaa agggttgcac ctcatcggca gataaattca ccgaaaccat tgccccggaa
     1021 ggcatttgct gcatcaaccg tccccgagtg gcaactaatg ccaaagcatc ttctaaactg
     1081 aaaacacctg ccagacaagc ggcgacgtat tccccaatgc tatgcccgat cagggcttgg
     1141 ggttgcactc cccaggacat ccataattta gccagggcgt actcgatcgc aaaaagtaca
     1201 ggttgggtaa tcgccgtttg cttgagttgg tctgttgcct gttctacgtc ttctggggct
     1261 ggatacaaac aggagcgcaa atcgataccc agatgaggtt ggagtaggtc aaaacagcga
     1321 tcgcattctt ctcggaatgt tggttcactc tgatacagtt cccgccccat gttgacatac
     1381 tgcgctccct gtccagtaca taagaacaca atcgagcgat cgcttgattc ctgaaattgg
     1441 ctaaaaactc gttgcggatt ccctgattct agggcgttta cggcatcttc aaggtcttgg
     1501 gcgacgacca tgcggcgatg ctcaaacctc cgacgaccca cttggagagt gtaagcgata
     1561 tccgctaagt tgaggtctgg atgctgctgt aaatgagacg ccagattcct ggttgctgtt
     1621 gccaaagccg aagccgtttt agcagaaatc accaacagat gagactgtct ctcctgttga
     1681 cccgttaagg tatcagttgt ctccagaacc ttagcctcga cagcaggcgc ttcttccaga
     1741 attacgtgga catttgtgcc gccaaatccg aaggaactca ccccagcacg gcgaggagtg
     1801 ccattcctct tccattcaga acagtgggta ttcacataaa aagggctatt tgcaaaatca
     1861 atttgcggat tgggtgtctc aaaattcaga ctaggaggta atacttgatg atgcagagct
     1921 aaagccgttt taattaagcc cgttatccca gcagcagcat ccaaatgccc cacattagtt
     1981 ttcactgaac cgatcgcaca gtatcctttt ttatcagtcg tgtctcgaaa tgctcgcgtc
     2041 attgctgcaa tttcaatcgg gtcccccaaa ggagttccgg tgccatgggt ttccatatag
     2101 ctaattgtgt ctggctccac ttcagccatg agttgagccg ctcgaatgac ccgggcttga
     2161 ccctcttcac tcggcgctgt gtaacccact tttaacgcac catcattatt aatcgctgaa
     2221 cctttgatca ccgtataaat ataatcccca tccgccaaag catcctcgag tcgtttgagg
     2281 acaactacac caattccgtt cccagcaatt gtgccatttg ccttgctatc gaatgctcga
     2341 caatgaccat caggagaaac gatttcctct ggtgataggg ttaactcgtt ctgcggaact
     2401 ttcaccgaaa caccagccgc caaagccata tcacattcgc cacttaataa actttggcag
     2461 gctaaatgaa cggcaactaa tgaactggaa caagccgttc ctacactaac actcggtccc
     2521 ttgagattta atttatagga aacgcgggtc gggacgtaat ccttatcaat gccaaccagc
     2581 gtttgtaaga atcccctaga ttccatcaat tcccggttag gataaaggtt atggaacgag
     2641 taggtactca tccccacacc cgcataaacg ccgatgggtc gttcttctcg ttcagtgtca
     2701 tagcccgcat tttctaaagc ttcccaagca cattctagaa agaggcggtg ttgggggtcc
     2761 atggcttccg cttctctggg gttgaagcca aaaaatgagg catcaaattg ttcaacatcc
     2821 tctaggatag aaccggattt gatcgtctgg cgggcgggtt gatgacccgt tgatgttacc
     2881 tgactattct gttgaaccgc tggaaactcg gtaattaatt caacaccatt ttgcaaattt
     2941 tcccaaaatt gatcaatggt atgacttttc ggaaaacgac cggaaattcc gatgatggca
     3001 atttctaatc cgtttggctc gctcgtcata ataactgcgg gtactctcta acttaaatac
     3061 tctatgattg gctcgtttca attcgattag gctaacgagg acgcgaccta gatttgtcaa
     3121 atcgttgctt caggcgactc ttgcctcggc taaggttttg tttaaattga atggagtctt
     3181 gattgaaacg gttgcttgaa tgtcctggcg ataaatgttg tgataataac cgaatcgttg
     3241 gcagtttaaa taaatcaacc actgataaac atgttacctc attattcggt aatttgtctt
     3301 ttattttctg ataaatcttt gtaacaagta atgaatttcc tcccaggtca aataaattat
     3361 cattaatccc aactttttcg acaccgagta cctcttgcca aactgtagta atcatttgtt
     3421 caatctcagt ctggggagca acataagaaa cttctatggt ctgaagcgaa tcggcttgag
     3481 tcggtagcgc acggcggtct actttaccat tagctgatag gggaaactca tccaaaaata
     3541 cataagctga cggtaacata tagtccgata gcttctgttt aagtaaatgg ttaatttctt
     3601 ctggagtagg tgttggtgtc tggtcagaaa ggatgtatgc cactaaccgc tggttccctg
     3661 gctgttcgcc aaccaccgtc acaattgccg atcgcacggc tggatgctgg gtcaaagtgg
     3721 tctcaatttc tcccgcttca atacggtatc cccgaatctt aatttgaaag tctactcgtc
     3781 ctaaaaattc aatgttgcca tcaggacaat atcgccctaa atctccggtg cgataaatcc
     3841 gttccccggt acaaggatga gtgatgaaat tagcctgggt tttttcagta tcccgccagt
     3901 accctttggc taactgcact cccgcacagt acatttgacc gggaacccaa gcgggacaat
     3961 cttctaaagc ttcgttcaaa atgtagtatt ttgaattagc catcggttga ccataaggaa
     4021 tactctgcca attggattca acctgttcaa tcaaatagcc gatattccaa attgtggttt
     4081 ccgtgggtcc gccaatactt aaaacttgga tatctggaac taaagctttc agccgattgg
     4141 gaagggaaac gggtagccaa tcccctccca aaattgccaa acgcaagctc tctggaagag
     4201 ctaccgattg cccttgggca tagtccacta gcatttccat catggcgggg actgagttcc
     4261 acagcgtcac ctgttctcgt actattaatt cagcccagtg actggggtct ttcgtaccgc
     4321 aagcatcagg catgacaatc gtgccaccag cactcaaaag accaaaaatg tcataaacag
     4381 ataggtcatg attgagagcg gtaagggcta aaattcgatc ctggaaacta atattaaaac
     4441 gctgattcgt atgaacaacc acatttacta cgttgcgatg agtaatcatc acccctttag
     4501 gcaaccctgt ggaaccggat gtataaataa cgtaggctaa atcatcggga gtttggattg
     4561 gctggagtgg ttccttacgt tcttgggtaa agtcttctgt gtctatacac agccgatgaa
     4621 ta
//
