LOCUS       c00418_3300000..       12206 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300000353.a:ElkS_mat_MD6ADRAFT_1000959.
ACCESSION   c00418_3300000..
VERSION     c00418_3300000..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 04:55:41
            Original ID  :: 3300000353.a:ElkS_mat_MD6ADRAFT_1000959
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12206
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12206
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1814:5066](-)"
                     /cutoff="20000"
                     /detection_rule="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C) or cds(LANC_like and (Pkinase or DUF4135)))
                     and not (YcaO or TIGR03882))"
                     /neighbourhood="10000"
                     /product="lanthipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(1815..5066)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C) or cds(LANC_like and (Pkinase or DUF4135)))
                     and not (YcaO or TIGR03882))"
                     /neighbourhood="10000"
                     /product="lanthipeptide"
                     /protocluster_number="1"
     cand_cluster    1..12206
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C) or cds(LANC_like and (Pkinase or DUF4135)))
                     and not (YcaO or TIGR03882))"
                     /kind="single"
                     /product="lanthipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12206
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide"
                     /region_number="1"
                     /rules="((LANC_like and (Lant_dehydr_N or Lant_dehydr_C) or
                     cds(LANC_like and (Pkinase or DUF4135))) and not (YcaO or
                     TIGR03882))"
                     /tool="antismash"
     CDS             complement(2..1762)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 148; E-value: 6.5e-45)"
                     /gene_kind="transport"
                     /locus_tag="ctg418_1"
                     /sec_met_domain="Peptidase_C39 (E-value: 2.9e-36, bitscore:
                     113.4, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKYPVVLQHNEEDCGAACLAAIAKYYGRIFSINRVREVAGTGPLG
                     TTLLNLKQGAKALRFDPRGVKVPIELIDQKIIPLPGIIHWNGNHWVVLYERKGRKYAIA
                     DPAIGIRYLSKKELLTGWTNGAMLLLQPRPEFPSQPDDRHKIGSFQRLSQRFWEKRGLL
                     AEVLLINGVFGCLSLTSPFLLQILTDDVLIRGDEQLLNGVIIAVLLSHLLRSSLRFVQS
                     HLIAHFAQGLELNLVLEFCRSILGLPLAYYESHRSGEVASRLRDIQAVNQLISQVGILL
                     PSQLFIALASLGFMLVYSRKLLLVTLVISATMTLSTLVFLRQLKQKTHSLLALTAENQG
                     ILVETFKGALVLKTKNAVPQFWEEFQSRFGRQANLNFKRLKIAIINAVFSGFVLLSGEG
                     ILLWFGGQLVFANQMSIGQLIAFNALNRNCLNFITSVIDFVNQFAFTEAALQRLNDVID
                     ATPEEQDNLFKPQVNLANKAEIVCNNLTFHHPGRVELLNDFSLTLPGGKAIALIGKSGC
                     GKSTLAKLLAGLYFPDSGTIRIGDYNLDDLSLDCLRQQIVLIPQEAHFWSRSIIENLSL
                     GDLPVGFSEIV"
     CDS             complement(1815..5066)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070:lanthionine synthetase C family protein (Score:
                     1057.5; E-value: 0)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg418_2"
                     /sec_met_domain="LANC_like (E-value: 1.7e-66, bitscore:
                     213.4, seeds: 47, tool: rule-based-clusters)"
                     /sec_met_domain="DUF4135 (E-value: 7.2e-120, bitscore:
                     389.6, seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDRVIGQTAPWYRALTLIERIPDSGTIREDSDTDGFNQDLAERKM
                     QRWCSQIPFTNSAYFDQRLAIEGMTREQFRDRLGESVESLVKRFPHPPHWLEELQQAFS
                     RLNFTNVQIAPVAQLSPERATPTFLYGIKPLLSHAIARLDAGIGELEKRYSTLPFDRQT
                     IKGLLVANLPDQLITMISQTMVLELNVARLQGQLSGETSTERFHNFIQELDNPERAIAL
                     LQEYPVLARQLVIHLEQWVDASLEFLDRLCSDWQDICQTFTPQTHPGILVQVQQGAGDT
                     HRGGRSVMILKFSSGFQVVYKPKSLAIDCHFQELLQWLNQRGQHPPFFTLKIINRYTYG
                     WVEFLSASSCTTPEQVERFYWRMGGYLALFYVLEATDFHLENLIAAGEHPVPIDLETLF
                     RPVGSAPDSPASVLMANRKMGESVMGVGLLPQRTNIQEASPGIDTSGIGAIGGQTLPTQ
                     SPQLTGIGTDEMRVRRQPGRLNRSKNRPTLNGDVVNVLDYQEAIETGFATIYRLIKEHR
                     EDFCSTWMTTFAQDEIRVVLRDTRLYGLLLQESFHPDVLRDALDRDRLFDRLWVDVPNR
                     PFLDQVIPWEKKALWRGDIPLFSTYANSCDLWSDGERITNFFDESGIERVERRIRQLSE
                     TDLDEQRWFIRTALTALKLESPNPGHSSYHLVEPETIPDPKQLCKHSLQIAENIASRLE
                     SLALQDNHQASWIGLVSVSQGYWTLKPLSWDLFAGISGIALFLGYFGAMTQTERYETLA
                     RDALSTVLHQVEFDQNLIRSIGGFNGWGGLIYTVTHLGSLWQNQDLYDRALKWVNQLPR
                     LIEQDKQLDIVSGSAGCIIALMNLYRCIGNEDIKAVALQCGERLLACAQPMERGIGWVT
                     LPHKKPLGGFSHGAAGIALALLELAAFTGEERYKNAAVAALEYERSLFSEPAKSWRNRL
                     QEDEENFAVGWSHGATGIGLARWRMSAYLDDPEIYSEIDAARETTLNRGFGYNHSLCNG
                     DLGNLELLWRGKSGIEVENESQELWHKRYLQKTAAVLDSLEQQGCYCGVPGGTEVLGLM
                     NGLAGIGYGLLRLVHPDRVPSVLVLDPPISRHYHV"
     CDS             complement(5011..5154)
                     /locus_tag="ctg418_3"
                     /transl_table=11
                     /translation="MKIILVYLSMIIIITQKGNTGKPLHKAEQDGSRDRANSTVVSGAD
                     VN"
     CDS             5185..7068
                     /locus_tag="ctg418_4"
                     /transl_table=11
                     /translation="MLQMYRFRGKVIVGISAVVLLCGRADTAVAREEVIREVPSMSSVQ
                     FHVDESVVLFPEEGDPMSQVNSVSQLRDVFPGDWAYEALRTLVERYGCIAGYPNGTFQG
                     NRALSRYEFAAGLNACLQQIERIFAENPGDLGHQDDVNTLQRLVQEFETELVTLGTRVD
                     NLEDRTASLEANQFSTTTKLQGEVIIAVTDVLVGDGTQVTFPSVFSPTGTITRESPEQN
                     TVFANRVRLNFLTSFTGEDELKIGLASGNFPHPDRGDGGFQYGPNPLFGFFGGREFSPE
                     GQQTFNDIASLPANNTVGLTSLSYEFSLGEKLRTVIMAAGGEHHDYIPTTFSLWDDDNG
                     GTGSLSVFGQRSGIYNFESGAGLGFTYHLSDAISLSAGYIATYANEPSSARSTNPLAGG
                     LFGGRYSALAQLTVKPSDTFSFGLTYNHSYHPARGPFSSTPIFLADQGTALSNSPIIPA
                     QEVSVDSYGVGALWQVSPQFAINGWFAYSRVNSNPDSAGIFQGGSFVDVDYEGSSADIL
                     TYGIALAFPDLGGEGNLGGLVIGASPYATRAEVPTPFQTGGNWFLGSDLGEDSTDLISD
                     NAIPWHIEGFYRYKLTDHIYLTPGVIWLTAPNQSARNPDVVIGTLRATFLF"
     CDS             7121..7903
                     /locus_tag="ctg418_5"
                     /transl_table=11
                     /translation="MIIAVAGLPGAGKTTWIRQQLAVANQPVLYFSPGSQPVPIDITGI
                     TVEFPQVTLLKEGDEYRLLDLARLECLAYIELGFHLDLESLEPLLSALDHLCYRRVAVM
                     PPNVQDTGWHVWADQVVPGVTIATPEGNPELWRAPISGQVLDPASLDVFWAELTQGAYG
                     NVNRAKGIFDLADGRAFYFDFVAGINSTYTELALPRWLEGRPQRFSGIEVVGVALDKSA
                     IAQTLKDCCLSDVAVHHYQQQIKESLAILDPEEEEEEA"
     CDS             7900..8709
                     /locus_tag="ctg418_6"
                     /transl_table=11
                     /translation="MKLAVISCIHGNYPALDAVLLDIDHQNADKIVCVGDLVGYGPHPN
                     AVVEQIRSLDIPTCQGCWDEDVVEGLNACECSYPSLLAEKRGRIAHEWTNQEIHPETRE
                     FLAQLPYSLKEGNLCFVHGSPHSNHEYLLPELDAFLAVERVLSTGADVLFCGHTHLPYV
                     RTLAGGQLQVKMSSEEQQQQQTFQAPLKRIINVGSVGEPRHGRPNATYVIYDNETEQVT
                     LREVEYDYQKTCAAIIDKGLPPIFAWRLARGLEYAEKADDPTHICAR"
     CDS             8834..9541
                     /locus_tag="ctg418_7"
                     /transl_table=11
                     /translation="METWAILSGIEGNIVAYEAVISDIQHQNRGVNDIYILGDFISSRP
                     ESEQVVRRIRSPKPNECLPKICTGWWEEQCLILHGLAATGEPTQLIENYGADTVKLLWD
                     AVSRQTVEWIRRLDFGFLELDCLLIHGSSVSVDDELTPQTPPWQMCDRLMRVGATNLFC
                     GRSGLTFEYQLQGGSVSSQITTLEGQQSVQTATASPRRVIGVGNVGREPGKATYTFYEP
                     DTNRVDFRTIRYG"
     CDS             9791..9979
                     /gene="allorf_09791_09979"
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="allorf_09791_09979"
                     /protein_id="allorf_09791_09979"
                     /tool="antismash"
                     /transl_table=1
                     /translation="VQIRRCPAAVMRLRSLSQNARRMSSNFSQIISSICEVQMYTIMNS
                     LIPRFYALIVPEIRYRC"
     CDS_motif       9791..9874
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: VQIRRCPAAVMRLRSLSQNARRMSSNFS"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /locus_tag="allorf_09791_09979"
                     /prepeptide="leader"
     CDS_motif       9875..9979
                     /leader_sequence="VQIRRCPAAVMRLRSLSQNARRMSSNFS"
                     /leader_location="[9790:9874](+)"
                     /monoisotopic_mass="3990.1"
                     /locus_tag="allorf_09791_09979"
                     /predicted_class="Class II"
                     /prepeptide="core"
                     /peptide="lanthipeptide"
                     /aSTool="lanthipeptides"
                     /score="-4.50"
                     /alternative_weights="4010.8"
                     /alternative_weights="4028.8"
                     /tool="antismash"
                     /core_sequence="QIISSICEVQMYTIMNSLIPRFYALIVPEIRYRC"
                     /molecular_weight="3992.8"
     CDS             10310..12205
                     /locus_tag="ctg418_8"
                     /transl_table=11
                     /translation="MSIQTATVGYPRIGKNREVKKALEAFWSNKLDAESLWETVRQVEE
                     TNWQTQREAGIDRIGIGDATLYDSVLDWSIYLGLIPERFRHLSGLEQYFAMARGKEGIP
                     ALEMTKWFDTNYHYLVPEISAQLQPTDFNPVLATVKRAQQILGKRATPIILGPMTLLRL
                     SRLDMPISEIIRPLCDRYVNLLQALKPLGIEEVQIHEPALVLGDTAKFKDDYESTYASL
                     VQVGIPLDLVTYFDDLGESYPWVIQLPVASISLDFTRGRNLEQLKRHGFPSDKRLGVGI
                     VDGRNIWQIRPDRLLPILDDIKPITSNLSIQPSASLQFVPYDATRETKLPEPLRNVLSF
                     AEQKLQEVVILAQTLQGEDRRSQLQDIATGQTAFEQFSPPNTQVQQQLQSLNVDAFERS
                     LPYAQRQPLQLQLPPFPTTTIGSFPQTSQVRKLRRQWKRGEITLADYKKAIDAEIAQCI
                     RYQEEAGLDVLVHGEFERTDMVEFFGQQLQGFAFTQHGWVQSYGSRYVRPPIIYGDVVR
                     QAPMTVREFKVAQSLTEKPIKGMLTGPVTMINWSYPRTDISRQEQAFQIALALRQEVAD
                     LEAAGATIIQIDEPALREGLPLKSERWQDYLSWAVDAFRLSAGIAKPQTQIHTHMC"
ORIGIN
        1 gaacaatctc agaaaacccg acaggtaaat cgcccaaact aagattttcg ataatcgaac
       61 ggctccaaaa atgagcctct tgaggaatca aaacaatttg ctgtctgaga caatctaaag
      121 acaagtcatc aagattgtaa tcgccaatac gaattgtgcc agagtccgga aaatataacc
      181 cagccaacag ttttgccaac gtactcttcc cacaacccga tttcccgatt aaagcgatcg
      241 ctttaccccc aggaagggtc agggagaagt cgttgagtag ttcaactcga ccgggatgat
      301 gaaaggttaa attattacaa acaatttcag ccttgttcgc caagttaacc tggggtttaa
      361 ataggttatc ttgctcctcc ggtgtcgcat caatcacatc atttaaccgc tgtagagcgg
      421 cttccgtaaa cgcaaattgg ttgacaaaat cgataacact ggtgatgaaa tttagacaat
      481 tgcgattcag cgcattaaac gcaattaatt gtccgatgct catttgattg gcaaaaacca
      541 actgaccgcc aaaccacagc aaaattcctt caccacttaa caaaacaaac cccgaaaaca
      601 ccgcattaat aatcgcaatt tttaatcgtt taaaatttaa atttgcctgt cgtccaaatc
      661 gagattggaa ttcttcccaa aactgaggca ccgcattttt agttttcaga accagcgctc
      721 ccttgaacgt ttctactaaa atcccttggt tttcggcagt taacgccaga agactgtggg
      781 ttttctgttt cagttggcga agaaacacta acgttgaaag cgtcatggtt gctgaaatta
      841 ccaacgtcac cagcaatagt tttcggctat aaacgagcat aaatcccaga gatgccaagg
      901 caataaacaa ctgactagga agtaaaatcc ccacttgaga aatcagttga ttaaccgctt
      961 gaatatcacg caaacgactc gccacctcac cactgcgatg agattcgtaa tacgccagag
     1021 gaagtccgag aattgaacgg caaaactcca ggactaaatt aagctctaaa ccttgagcaa
     1081 aatgggcaat taaatgagac tggacaaatc ggagactact ccggagtaag tgcgacagta
     1141 agacggcaat aatcacacca ttaagcagtt gctcatcacc gcgaattaag acatcatcgg
     1201 tgagaatttg cagtaaaaat ggagaggtga gagatagaca gccaaaaacc ccgttaatca
     1261 gcaacacttc cgccaaaaga cctcgttttt cccagaagcg ttgacttaaa cgttgaaaac
     1321 tgccaatttt atgacgatca tccggttgag agggaaattc tggacgcggt tggagtagaa
     1381 gcatggctcc attagtccac cccgttagta actctttttt cgataaatac cgaatcccaa
     1441 tggctggatc agcaatcgcg tattttcttc ctttgcgttc gtacaaaact acccaatgat
     1501 taccgttcca gtgaataatt ccgggtaaag gaattatttt ttgatcaatg agttcaatcg
     1561 gaactttcac acctctcgga tcgaatcgaa gggcttttgc cccttgtttg aggttgagta
     1621 atgtagtccc caagggtcca gtaccggcga cttctcgaac ccgattaatc gagaaaatcc
     1681 gaccataata tttagcgatc gcggctaaac aggctgcgcc gcaatcttct tcattgtgct
     1741 ggagtacaac tgggtatttc atcagtcacg ccgcgaaact ttaatcttat tcaaaccgaa
     1801 ttaactccat tgtcttagac gtggtaatgc cgggaaatag gcggatcgag aactaaaacc
     1861 gaaggaacgc gatcggggtg aaccaaacgc agtaagccat aaccgattcc ggctaaaccg
     1921 ttcattaaac cgagaacttc tgttccccca ggtacaccac agtaacaccc ctgctgttca
     1981 aggctgtcca aaacagcagc cgttttctgg agataacgtt tatgccataa ctcttgagac
     2041 tcgttttcca cttctattcc agattttccc cgccagagta attctaaatt tcctaaatct
     2101 ccgttgcata acgaatgatt gtaaccaaag cctcgattta gggttgtttc cctagcggca
     2161 tcaatttctg agtaaatttc tggatcatct aaataggcgc tcattctcca gcgagccaaa
     2221 cctattcccg ttgcaccatg actccacccc acggcaaaat tttcttcgtc ttcctgtaat
     2281 ctatttcgcc aacttttagc gggttccgaa aagagacttc gctcatattc taaagcagcc
     2341 accgccgcat ttttgtagcg ttcttctccc gtgaatgcgg ctaattctaa caaggctaaa
     2401 gcaattcccg ccgcaccgtg agaaaatccg ccgaggggtt ttttatgggg aagggttacc
     2461 caaccgatgc ctcgttccat gggttgggca caagccagaa gacgttcacc gcattgtaaa
     2521 gcaacagctt taatgtcttc attaccaata cagcgataaa gattcattaa ggcgataata
     2581 catccggctg aaccggaaac aatatccaat tgtttgtctt gttcgattaa cctaggcagt
     2641 tggttaaccc atttcaaggc acgatcatat aagtcctgat tttgccataa actgcctaaa
     2701 tgagttaccg tataaattaa tccaccccaa ccattaaatc ccccaatcga acgaattaaa
     2761 ttttgatcaa actccacctg atgcaataca gtagacaggg catctcgcgc taaggtttca
     2821 tagcgttctg tttgagtcat cgccccgaaa taacccagaa atagagcaat cccagaaatt
     2881 ccggcaaata aatcccaact cagcggttta agagtccaat acccttgact aacggagact
     2941 aacccaatcc aactggcttg atggttatct tgcaaggcaa gggattccaa tcgtgaggca
     3001 atgttctcgg ctatttgtaa cgagtgtttg cacaattgtt taggatctgg aatcgtttcc
     3061 ggttccacta aatgataact tgaatgccca gggtttgggg attccagttt taacgccgtt
     3121 aaagctgtgc gaataaacca acgttgctcg tctaaatcgg tttcactcaa ttgtcgaatt
     3181 cgacgttcta ctcgttcgat tcccgattca tcaaaaaagt tcgtgattcg ttcaccatca
     3241 ctccacaaat cacacgaatt tgcataggtg gaaaacaagg gaatatcacc acgccataaa
     3301 gcttttttct cccagggaat cacctgatcc agaaacgggc gattcgggac atcaacccaa
     3361 agccgatcaa agaggcgatc gcgatccagt gcatcccgca aaacatcggg atgaaaactc
     3421 tcttgtaata ataatccata gagtcgagta tcccgcaaaa ccactcggat ttcgtcctga
     3481 gcaaaggttg tcatccatgt agaacaaaag tcttctcgat gttctttaat taaccgataa
     3541 atcgtggcaa atccagtttc tattgcctct tggtagtcta aaacattaac cacgtcccca
     3601 ttcaacgtcg gtcgattttt acttctattt aacctccctg gctggcgacg cacgcgcatt
     3661 tcatcggtgc ctatgccagt taattgaggg gattgagtgg gcagagtttg acccccaatg
     3721 gcaccgattc cactggtatc aattcctggt gaggcttctt ggatgttagt gcgttggggt
     3781 aatagtccca ctcccattac agactcaccc attttccggt tagccattaa tacagatgct
     3841 ggggaatcgg gggcgcttcc cacgggacgg aataaggttt ctaagtcgat gggaacggga
     3901 tgttcgccag cggcaatcag gttttctagg tgaaaatctg ttgcttctaa aacgtagaat
     3961 agtgctaaat aaccgcccat gcgccagtaa aatcgctcaa cttgttcagg cgtggtacaa
     4021 ctggaggcag acaggaattc aacccatcca taggtgtacc gattgataat ttttaaggtg
     4081 aaaaatggtg gatgctgacc gcgttgattg agccactgaa gcagttcttg aaaatggcag
     4141 tcaatggcta atgatttggg cttataaacc acctgaaacc cggagctaaa ttttaggatc
     4201 atgaccgatc gcccaccgcg atgggtgtcg cctgcgcctt gttgcacttg cactaaaatc
     4261 cctggatggg tttggggagt gaaagtctgg caaatgtcct gccaatctga acagagacgg
     4321 tctaaaaatt ctaagctggc gtccacccat tgttccaggt gaatgactaa ttgtctggct
     4381 aaaacgggat actcttgcag cagggcgatg gctcgctctg gattgtctaa ttcttggata
     4441 aaattgtgaa atcgttcggt tgatgtctcc ccagataatt gtccttgtaa ccgagctaca
     4501 ttcagttcta ataccatggt ttgactgatc attgtgatca actgatcagg gagattggca
     4561 actaaaagtc ccttaatagt ctgccgatca aagggtaaag tggagtaacg tttctctaat
     4621 tcgccaattc cggcgtctaa acgagcgatc gcatgactca gtaagggttt aatcccgtag
     4681 aggaaagttg gtgttgctcg ctcaggagag agttgcgcca caggtgcgat ctgaacattt
     4741 gtgaaattta ggcgagaaaa cgcctgctgg agttcctcta accaatgggg cggatgggga
     4801 aaacgcttga ccaaagattc aacggattca ccgaggcgat cgcgaaactg ctctcgggtc
     4861 attccctcaa tagccaatcg ctgatcaaaa taagccgaat ttgtaaaggg gatttgggaa
     4921 caccagcgct gcattttgcg ttcggctaag tcctgattaa agccatctgt gtcagagtct
     4981 tccctgattg tccctgagtc tgggattcgt tcaattaacg tcagcgcccg ataccacggt
     5041 gctgtttgcc cgatcacgcg atccatcctg ttctgccttg tgtagtggtt ttcccgtatt
     5101 tcctttttgg gtgataatga ttatcatact caaatatacc agaatgattt tcattttcac
     5161 ctactaaggt gtgaggagga gaaaatgcta cagatgtaca ggttccgggg taaggtgatt
     5221 gtcggtattt cagcggttgt cctgctgtgt ggtcgtgctg ataccgccgt agcaagggaa
     5281 gaagtcatcc gtgaagtccc gtccatgtcc agtgttcagt tccacgtcga tgaatcggtg
     5341 gtgctttttc cagaggaagg tgatcccatg agccaagtta actccgtgtc tcaactgcgg
     5401 gatgttttcc ctggagactg ggcgtatgaa gccttacgga ctctggttga gcgctatggg
     5461 tgtatcgctg gctatcccaa tggcacattt caagggaatc gagcgttgag tcggtatgaa
     5521 tttgccgccg gattgaatgc ttgcttgcag caaatcgagc gtatcttcgc ggaaaaccca
     5581 ggggatttag gtcaccagga cgacgtaaac actttgcaac ggctggtaca agagtttgaa
     5641 accgaattag tcaccctggg tacacgggtg gataatctag aagatcgtac cgcgtctctg
     5701 gaagcgaatc agttttccac caccaccaaa ctgcaaggag aagtgatcat cgccgttacc
     5761 gatgttttag taggagacgg aactcaagtg acgttcccgt cagtctttag cccaacggga
     5821 accataactc gtgaaagtcc tgaacaaaat acggtttttg ccaaccgcgt tcgtctcaat
     5881 ttcctcacca gttttacggg tgaggatgag ctaaaaatag ggcttgccag tgggaacttt
     5941 ccccaccccg atcgaggcga cggcggattt caatatggtc cgaatcccct atttggtttc
     6001 tttgggggac gggaattttc ccctgaaggt cagcaaacct ttaacgatat cgcgtcctta
     6061 cctgctaata atactgtagg gttgacgagt ttgagctatg agttttccct gggcgaaaag
     6121 ctgagaaccg tgattatggc agccggcggc gaacatcacg actatattcc caccacgttt
     6181 agtctttggg atgacgacaa tgggggtaca ggttctctgt cggtttttgg acaacgcagt
     6241 gggatttata attttgagtc aggagccggt ctaggattca cttaccactt gagtgatgcc
     6301 attagtctga gtgcgggtta tatcgccaca tacgccaatg aacccagttc cgcccgttcg
     6361 acgaatcctc tcgctggggg tttatttggc ggtcgatatt cggctttggc acaattaacg
     6421 gtcaaaccca gcgatacttt ttcctttggt ttgacctata accacagcta tcatcctgcg
     6481 aggggtccgt ttagcagtac acccatcttt ttggcggatc aaggaacagc cttgagcaat
     6541 agtccgatta ttccagctca agaggtatcg gttgattcct atggtgttgg tgcgttgtgg
     6601 caagtgagtc ctcagtttgc catcaatggc tggtttgcct acagtcgcgt caatagtaac
     6661 ccggacagcg ccggaatttt tcaaggggga agcttcgtcg atgtagatta tgaaggcagt
     6721 agcgctgata ttcttaccta tggcatcgct ctggcgtttc ccgacttagg aggggaagga
     6781 aatctcggtg gtttggttat cggcgcttct ccttatgcga ctagagcaga agttccaaca
     6841 ccgttccaga ctgggggaaa ttggttcttg ggttctgatt taggagaaga ttctactgac
     6901 ctgatttcag ataatgcgat tccttggcat attgagggat tctatcggta taagctgacc
     6961 gatcatattt atctgactcc tggtgtaatt tggttgacgg cgcctaacca atccgcgcga
     7021 aatccggatg tagtgattgg tacgctccga gcgacgttcc ttttctaagg ggaacccgtt
     7081 tgagttatta taatgataat cattcccaag atttttctca atgattattg ctgtcgctgg
     7141 tttaccggga gccggaaaaa ccacttggat tcgacaacag ctagccgttg ctaaccaacc
     7201 cgtgctgtat tttagtccgg gttctcagcc tgttcccatt gatataacgg gtatcactgt
     7261 cgaatttccc caagtcacac ttctcaaaga aggggatgag tataggttgt tagacttagc
     7321 tcggctggag tgtcttgcct atatagaact gggatttcat ctagatttag agtccctcga
     7381 gccactgttg tccgcattag atcacctctg ctatcgtcgc gttgccgtga tgccacccaa
     7441 tgttcaggat accggatggc acgtttgggc agaccaagtc gtgcctgggg tgacaattgc
     7501 caccccagag ggaaatcctg agctttggcg tgcgccgatt agcggtcaag tgcttgatcc
     7561 agctagtctg gatgtctttt gggcggagtt aacccaggga gcctatggca atgtgaatcg
     7621 agccaaggga atttttgacc tagccgatgg acgcgccttt tattttgatt ttgtcgcggg
     7681 gataaatagt acctacaccg agttagcgct tccgcgttgg cttgaaggtc gtccccagcg
     7741 cttcagtggg attgaagtgg tgggtgtggc gttggataag agcgcgatcg cccaaacact
     7801 gaaagattgc tgtttatcgg atgtagctgt tcatcattac caacaacaaa tcaaagaatc
     7861 cttagctatt ttagatccag aagaagaaga agaagaagca tgaaacttgc tgttatctcc
     7921 tgcattcacg gaaactaccc agccttagat gccgttttat tagatattga tcaccaaaac
     7981 gctgacaaaa tcgtttgtgt tggcgactta gtgggttatg gaccccatcc caatgctgta
     8041 gtcgaacaaa ttcgctctct cgatattccc acctgtcagg gatgttggga tgaagatgtt
     8101 gttgaaggat taaacgcttg cgaatgttcc tatccttcac tattagccga aaaacgagga
     8161 cgcattgctc acgaatggac gaatcaggaa attcaccctg aaacacgaga attcctcgcc
     8221 caactacctt atagcttaaa agaagggaac ctctgttttg ttcatgggag tcctcacagt
     8281 aatcatgaat acctgttgcc ggagttagat gcttttttag ccgtggaacg agttctctcg
     8341 acgggtgctg atgtcctttt ctgtggacat acccatctgc cttatgtgcg gacgttagca
     8401 gggggtcaac tgcaagtcaa gatgagtagc gaggaacagc aacaacagca aactttccag
     8461 gctcccctga aacggattat caatgtgggt tctgtcggag aacctcgtca cggacgcccg
     8521 aatgccacct atgttattta cgataatgaa accgaacagg taacgttgag ggaggttgag
     8581 tacgactacc aaaaaacctg tgcggcaatt attgataaag gcttacctcc tatttttgcg
     8641 tggcgattgg cacgaggatt ggagtatgcc gaaaaagcgg atgatccaac tcatatttgt
     8701 gcgcgataaa cctttcttgg tcataagtta acagaaggca gacggttgtc acgtttatcc
     8761 tgtctttaaa gcctgacaaa tgacaaacga cttctccacc gttaagtcca attctccccc
     8821 atactgaata acaatggaaa cctgggcaat tttaagtgga attgaaggaa atattgttgc
     8881 ttatgaagcg gtaatttccg atattcaaca ccagaataga ggcgtaaatg atatttatat
     8941 tttgggggat tttattagtt ctcgacccga aagtgaacag gtcgtgcggc gaattcgttc
     9001 tccaaaaccc aacgaatgtt tacccaaaat ctgtacaggt tggtgggagg aacaatgtct
     9061 gattcttcat ggattggcag ctacaggcga accgactcaa ctgattgaga actatggtgc
     9121 tgacaccgta aaattgcttt gggatgctgt ttcccggcaa acggttgaat ggattcgccg
     9181 cctagatttt gggttcttag aactcgattg tctactgatt catggtagca gcgtgagtgt
     9241 ggatgatgaa ttgacgcctc agacaccccc ttggcagatg tgcgatcgct tgatgcgtgt
     9301 gggtgcaact aacctatttt gtggtcgatc gggtttaact tttgagtacc aactgcaagg
     9361 aggttctgtg tcttcacaaa tcaccacgct tgagggtcaa cagtcggttc agacagcaac
     9421 agcatctcct cgtcgggtta ttggggtggg taatgtggga cgagaacccg gaaaagccac
     9481 ttacacattt tatgagccgg atacaaaccg tgtggacttt cggacaattc gttacggctg
     9541 aagcagaggg agcatgtcac ctctctggct aatggttacg atgccagagg ctcatatcat
     9601 ctgttttgtg gatatctgct ggcaacagag agtcataaaa cttaaccatt tccaccattc
     9661 cccttgttta ttcccctgct gagcaaaatc aggggagctg gggagacaaa aaagacataa
     9721 tggtgatata gtgaaaatca accttcggtt ctaacgggga tcagccgtta gaagtaatgg
     9781 ggaaagttcg gtgcaaatcc gacgctgtcc cgcagctgta atgagactga ggtctttgag
     9841 tcagaatgcc cgccgaatgt caagcaattt tagtcaaatc atttcatcca tctgcgaggt
     9901 acagatgtat acaatcatga atagtctcat cccgcgattt tacgctctga tcgtgccaga
     9961 aatacgctac agatgctaac tggcattact cgattggttt ggcaatttat ccatccaagg
    10021 cagtgcttct gctgtccgga aatatagcat tactatatcc aaggctttcc cgcctaggtc
    10081 agaatcgcct gaaccgttga accggatttt ctggcacaga ttctgccttt gaggaaattg
    10141 caccaattaa acacaaccta tagcatttca tcgctctaat gactccggga acaccgatta
    10201 attgcctgag gcattagata gcttgagtgc tgttccttga tggtgaagtg ctacccttag
    10261 cgcttgatca aatccgggct attacacctt aattaaaccc agaaaaacca tgtccattca
    10321 aaccgcaaca gtaggctatc ctcgcatcgg caaaaaccgc gaagtcaaaa aagccttaga
    10381 agccttctgg agtaacaaat tagacgcaga atccttatgg gaaactgtgc gccaggttga
    10441 agaaaccaac tggcaaaccc aacgtgaagc cggtatcgat cgcattggga ttggtgacgc
    10501 taccctctat gactctgtac tcgattggtc catttatctg ggattgattc cagaacgatt
    10561 tcggcatcta tccggtttag agcaatactt tgccatggca cgggggaaag aaggcattcc
    10621 cgccctggaa atgaccaagt ggtttgatac gaattaccac tacctcgtgc cggaaatttc
    10681 cgcccaactg caaccgacag attttaatcc ggttttggca acagttaaac gcgcccaaca
    10741 aattctggga aaacgggcaa ctccgattat tttaggcccg atgacactcc tacgattgag
    10801 ccggttagac atgccgattt cggagatcat tcgtcctctg tgcgatcgtt atgtgaatct
    10861 gctacaggca ctcaaaccct tgggtataga ggaagtccaa attcatgaac ctgccctcgt
    10921 tttgggagat acggctaagt ttaaagacga ctatgaatca acttacgctt cattggtgca
    10981 ggttggtata ccgctagatt tggtcaccta ttttgatgat ttgggtgaaa gttatccctg
    11041 ggtgatccaa ttacccgttg ccagcatcag tttagacttt acccgtgggc gcaatctaga
    11101 acaacttaaa cgccatgggt ttcccagcga taaacgcctg ggtgtgggta ttgtagatgg
    11161 acgaaacatc tggcaaattc gacccgatcg cctcttacca atcctggacg atattaaacc
    11221 aattacctcc aacctatcca ttcaaccctc cgcctcccta cagtttgttc cctacgatgc
    11281 aacaagggaa actaagttac ccgaacccct acgaaatgtg ctgagttttg ctgaacaaaa
    11341 actccaagaa gtagtaattt tggcgcaaac cctccaaggg gaagacaggc gatcgcaatt
    11401 gcaggatatt gccacaggtc aaacggcgtt tgagcaattc agtcccccca atacacaggt
    11461 tcaacaacag cttcagtcat tgaatgttga tgcctttgag cgatcgctcc cctatgccca
    11521 aagacagcca ctacaacttc aacttccccc atttccaacc accacaattg gctcatttcc
    11581 gcaaacctca caggtgcgga aactacggcg gcaatggaag cgcggcgaaa ttactctggc
    11641 tgactacaaa aaagcaattg atgccgaaat tgctcagtgt attcgctatc aagaagaagc
    11701 cggattagat gtgctggtgc atggtgaatt tgagcgcacc gatatggtag agttttttgg
    11761 gcaacaactc caaggttttg ccttcactca acatggatgg gtacaaagtt atggcagtcg
    11821 ctatgttcgt cccccgatta tttatggtga tgtcgtgcgt caagcgccga tgacggttcg
    11881 tgagtttaaa gttgcccagt cattaacgga aaaaccgatt aaagggatgc tcaccggacc
    11941 cgtaacgatg attaattggt cgtacccccg taccgacatt tcccgacagg aacaggcgtt
    12001 ccaaattgcc ttagccttgc ggcaagaagt ggcggattta gaagcagcag gagcgacgat
    12061 tattcagatt gatgaaccgg cattgcgaga gggtttaccg ctgaaatcag aacggtggca
    12121 ggattatctg tcttgggcag tggatgcgtt tcgtctcagt gccggaattg ccaaacccca
    12181 aacccaaatt catactcata tgtgtt
//
