LOCUS       c00426_3300000..       11350 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300000353.a:ElkS_mat_MD6ADRAFT_1001101.
ACCESSION   c00426_3300000..
VERSION     c00426_3300000..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 04:55:41
            Original ID  :: 3300000353.a:ElkS_mat_MD6ADRAFT_1001101
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 11350
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..11350
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[216:3744](-)"
                     /cutoff="20000"
                     /detection_rule="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C) or cds(LANC_like and (Pkinase or DUF4135)))
                     and not (YcaO or TIGR03882))"
                     /neighbourhood="10000"
                     /product="lanthipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(217..3744)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C) or cds(LANC_like and (Pkinase or DUF4135)))
                     and not (YcaO or TIGR03882))"
                     /neighbourhood="10000"
                     /product="lanthipeptide"
                     /protocluster_number="1"
     cand_cluster    1..11350
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C) or cds(LANC_like and (Pkinase or DUF4135)))
                     and not (YcaO or TIGR03882))"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03603 or TIGR03604 or TIGR03651 or
                     TIGR03678 or TIGR03693 or TIGR03798 or TIGR03601 or
                     TIGR03602 or TIGR03795 or TIGR03793 or TIGR03975 or DUF692
                     or TIGR01193)"
                     /kind="neighbouring"
                     /product="lanthipeptide"
                     /product="bacteriocin"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     region          1..11350
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /contig_edge="True"
                     /product="lanthipeptide"
                     /product="bacteriocin"
                     /region_number="1"
                     /rules="((LANC_like and (Lant_dehydr_N or Lant_dehydr_C) or
                     cds(LANC_like and (Pkinase or DUF4135))) and not (YcaO or
                     TIGR03882))"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03603 or TIGR03604 or TIGR03651 or TIGR03678 or
                     TIGR03693 or TIGR03798 or TIGR03601 or TIGR03602 or
                     TIGR03795 or TIGR03793 or TIGR03975 or DUF692 or
                     TIGR01193)"
                     /tool="antismash"
     CDS             3..143
                     /locus_tag="ctg426_1"
                     /transl_table=11
                     /translation="GGKGDFYLLYFITAQSAVKGVANPDLGGKVDLRVVILTLNLVSRN
                     N"
     CDS             complement(217..3744)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070:lanthionine synthetase C family protein (Score:
                     603.2; E-value: 1.5e-182)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg426_2"
                     /sec_met_domain="LANC_like (E-value: 1e-69, bitscore:
                     224.3, seeds: 47, tool: rule-based-clusters)"
                     /sec_met_domain="DUF4135 (E-value: 3.3e-119, bitscore:
                     387.7, seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTNLQPELVRIVEQACSLTERLVTGEISSNPSDADTRVKSRLEKW
                     CQTAAQGDLEKFQKRLAWDNINLSTINRLLGDFSLSGTQNLPAWVETFQAGIEAAASIP
                     IETLEPGKTYSFLAPDNPIPFEEIFLPFIQVARDKLTALTGDNYPSLNATELKLVGNAH
                     PTGYQRFRRCDNAYFSAIHPNLTAAACANLERSLLVSLSSFCSSSMELKFSAFRAKRQS
                     ALSRLLGQLQNSYTNTHYQAFIQHILQGEGLLAFFQDYPVLARLVATVTDFWVDATWEF
                     IQRLTTDWSTIQQTFQPDIELGQVDRINPCKSDPHNQGRSVIEVSFTSGLKLIYKPKDL
                     SLDVAYFNVLNWCNQHFIESPGFASLQPFKLLKVLNRATYGWVEFVEYLPCQNQAEIKR
                     YYQRAGQLLCLLYVLGANDCHHENVIACGEHPVLVDLETLMHHPFQEIAGSARKEGVEA
                     VSLAQRRLMDSVMRTGLLPHWHLGSDKRTAYDPSGLVGFGNQETSYQMPKWENINTDRM
                     VLTHETAQLSSQTNAPSLAGVIQAPKEYVNELVDGFEHQYRFLLAHREALLATDSPLAA
                     LSHQRVRCLFRPTQVYASVLQKSLHPKYLRDGVDHSIELEVLCRAFLGTDLKHPWWRIL
                     QAELQTLEQLDIPYFAADSDSDALPVVKGEMMVPCFAQPSYTQMIATIQRLNQDDLAEQ
                     VAIIRSSLLVVGEPNTATSDIKVRSRHFSARSAKALTTNSKVSGVRVRFDIDCSKWREK
                     SAAISVLDDQVSPISEEESVQQAIQIAQDLQRRAIQATDGSATWIGLGFLPQTNRFQLQ
                     PIGNSLYDGCSGIALFLAALTKITGNNEWRDLCLGALQPLRRILPDSDSESRQTVTQLG
                     IGGAAGLGSIVYSLVRISQFLGDGTLLADAKQAACLITRDRIAADQQFDLVAGAAGAIL
                     GLLTLHQVTADSGILAQAISCGEHLLNHRVISETGFKTWATGAEKPLTGFSHGAAGIAY
                     ALLRLYEVTQEVVFRKAAEDAIAYERHLFSPTQGNWLDLRSYALIDGKPTYMTSWCHGA
                     PGIGLARLGSLASLDTPDIRAEIAIALDTTRQFSWHNIDHLCCGNCGRMEVLLVAAQKL
                     LRPDLVETVKKQANWIVRRAKQVGGFHLFPQFPQDVYNPGFFQGTAGIGYQFLRLAHPD
                     LLPSVLLWN"
     protocluster    2285..11350
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[7284:8393]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03603 or TIGR03604 or TIGR03651 or
                     TIGR03678 or TIGR03693 or TIGR03798 or TIGR03601 or
                     TIGR03602 or TIGR03795 or TIGR03793 or TIGR03975 or DUF692
                     or TIGR01193)"
                     /neighbourhood="5000"
                     /product="bacteriocin"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      7285..8393
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03603 or TIGR03604 or TIGR03651 or
                     TIGR03678 or TIGR03693 or TIGR03798 or TIGR03601 or
                     TIGR03602 or TIGR03795 or TIGR03793 or TIGR03975 or DUF692
                     or TIGR01193)"
                     /neighbourhood="5000"
                     /product="bacteriocin"
                     /protocluster_number="2"
     cand_cluster    2285..11350
                     /candidate_cluster_number="2"
                     /contig_edge="True"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03603 or TIGR03604 or TIGR03651 or
                     TIGR03678 or TIGR03693 or TIGR03798 or TIGR03601 or
                     TIGR03602 or TIGR03795 or TIGR03793 or TIGR03975 or DUF692
                     or TIGR01193)"
                     /kind="single"
                     /product="bacteriocin"
                     /protoclusters="2"
                     /tool="antismash"
     CDS             complement(4146..4943)
                     /gene_functions="other (smcogs) SMCOG1157:hypothetical
                     protein (Score: 133.6; E-value: 1.5e-40)"
                     /gene_kind="other"
                     /locus_tag="ctg426_3"
                     /transl_table=11
                     /translation="MSKIVSIHSFRGGTGKSNTTANVAVTTASQGLRVGIIDTDIQSPG
                     IHVLFGIDQSKINRTLNDYLWNRCGVEETAYDVSPPEVTKNQGKLFLIPSSMNIGEISR
                     ILREGYNVALLNNGFKKLVSSLELDYLFIDTHPGINEETLLSVTISNILLIILRPDRQD
                     FQGTAVTVDVARKLKVAKLLLVVNRVPQKFDLNSVRQQVETTYNATVAGVLPNCEEMME
                     LQSSDLFCLRYPDHYISKEIRRIVDHIYEKPKSVGGLKKLFGR"
     CDS             complement(5198..5269)
                     /gene="allorf_05198_05269"
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="allorf_05198_05269"
                     /protein_id="allorf_05198_05269"
                     /tool="antismash"
                     /transl_table=1
                     /translation="LLFGQKVLFGVCNIQLRVGSHLL"
     CDS_motif       complement(5240..5269)
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: LLFGQKVLFG"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /locus_tag="allorf_05198_05269"
                     /prepeptide="leader"
     CDS_motif       complement(5198..5239)
                     /leader_sequence="LLFGQKVLFG"
                     /leader_location="[5239:5269](-)"
                     /monoisotopic_mass="1432.8"
                     /locus_tag="allorf_05198_05269"
                     /predicted_class="Class II"
                     /prepeptide="core"
                     /peptide="lanthipeptide"
                     /aSTool="lanthipeptides"
                     /score="-5.20"
                     /tool="antismash"
                     /core_sequence="VCNIQLRVGSHLL"
                     /molecular_weight="1433.7"
     CDS             5336..6193
                     /locus_tag="ctg426_4"
                     /transl_table=11
                     /translation="MVSNKFSLHRIALVALFVELLTTSSFPMLAQGRSLNQDGLTPWKI
                     STPLTHFPENQVEKSPTLHAQSIRFPTTGKPRRRRSAAVRGGTEEAVVPNSCGNSSDEQ
                     IVALLPPTEPVRTVAEHPTILVYLPENTAKQAEFYLKEADNDEIVYETTVTLPGDSGIV
                     SVPLPDNGTLPALEVGKTYTWHFFVICNEQDPTNEPYVEGQIERVEPSPNLVAELENAS
                     LRDRAAIYAEAGIWYDCLNSLAQLRRSAPNDSAIASDWAALLESVGLDTISQKPLISSS
                     GSPN"
     CDS             complement(6225..6680)
                     /gene_functions="other (smcogs) SMCOG1229:transposase
                     (Score: 83.9; E-value: 1.9e-25)"
                     /gene_kind="other"
                     /locus_tag="ctg426_5"
                     /transl_table=11
                     /translation="MIQKHQVQLSQTERQELIKLTKKGKISARKLRRAQILLLTDAGHK
                     DEEIATMLHLGVATVERTRKKFVEGGLDLALNERPRPGAVKKLDKKTEEFLIATASSKP
                     PPGKDCWTTQLLAEKLVQLQLVESISAETVRLLLKKIALNGDSKNKD"
     CDS             6735..6821
                     /gene="allorf_06735_06821"
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="allorf_06735_06821"
                     /protein_id="allorf_06735_06821"
                     /tool="antismash"
                     /transl_table=1
                     /translation="VIVNWNTTELSILLFSHQNQFCKSLFYP"
     CDS_motif       6735..6782
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: VIVNWNTTELSILLFS"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /locus_tag="allorf_06735_06821"
                     /prepeptide="leader"
     CDS_motif       6783..6821
                     /leader_sequence="VIVNWNTTELSILLFS"
                     /leader_location="[6734:6782](+)"
                     /monoisotopic_mass="1492.7"
                     /locus_tag="allorf_06735_06821"
                     /predicted_class="Class II"
                     /prepeptide="core"
                     /peptide="lanthipeptide"
                     /aSTool="lanthipeptides"
                     /score="-4.90"
                     /tool="antismash"
                     /core_sequence="HQNQFCKSLFYP"
                     /molecular_weight="1493.7"
     CDS             complement(6935..7051)
                     /gene="allorf_06935_07051"
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="allorf_06935_07051"
                     /protein_id="allorf_06935_07051"
                     /tool="antismash"
                     /transl_table=1
                     /translation="LPQEVSPLSQPSSGGNSEHHQKTTPFADFMVRLSKCIT"
     CDS_motif       complement(6971..7051)
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: LPQEVSPLSQPSSGGNSEHHQKTTPFA"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /locus_tag="allorf_06935_07051"
                     /prepeptide="leader"
     CDS_motif       complement(6935..6970)
                     /leader_sequence="LPQEVSPLSQPSSGGNSEHHQKTTPFA"
                     /leader_location="[6970:7051](-)"
                     /monoisotopic_mass="1275.7"
                     /locus_tag="allorf_06935_07051"
                     /predicted_class="Class II"
                     /prepeptide="core"
                     /peptide="lanthipeptide"
                     /aSTool="lanthipeptides"
                     /score="-6.40"
                     /alternative_weights="1294.6"
                     /tool="antismash"
                     /core_sequence="DFMVRLSKCIT"
                     /molecular_weight="1276.6"
     CDS             7285..7704
                     /gene_functions="biosynthetic (rule-based-clusters)
                     bacteriocin: TIGR03798"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg426_6"
                     /sec_met_domain="TIGR03798 (E-value: 2.2e-13, bitscore:
                     39.8, seeds: 22, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQSNIQSFNAEDLSAEELQLQKAQQVIDELFMAAESDEKLNEQL
                     EAAISPESLVEIATRQGYKLTVADLEMLHHYDQEQAQLNSDELDDDELSEQELELVAGG
                     RAKGLTSLTAPPKPVPSGFNPSPKSQGFPVPWWPW"
     CDS             7756..7947
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg426_7"
                     /transl_table=11
                     /translation="MLQPEIQALKAENLSTFNSDEDDELSEQELELVAGGNGFNPPTSE
                     PGWVHDPTCPNYRAGMEQ"
     CDS_motif       7756..7863
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MLQPEIQALKAENLSTFNSDEDDELSEQELELVAGG"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /locus_tag="ctg426_7"
                     /prepeptide="leader"
     CDS_motif       7864..7947
                     /leader_sequence="MLQPEIQALKAENLSTFNSDEDDELSEQELELVAGG"
                     /leader_location="[7755:7863](+)"
                     /monoisotopic_mass="2946.3"
                     /locus_tag="ctg426_7"
                     /predicted_class="Class II"
                     /prepeptide="core"
                     /peptide="lanthipeptide"
                     /aSTool="lanthipeptides"
                     /score="1.70"
                     /alternative_weights="2966.2"
                     /alternative_weights="2984.2"
                     /tool="antismash"
                     /core_sequence="NGFNPPTSEPGWVHDPTCPNYRAGMEQ"
                     /molecular_weight="2948.2"
     CDS             7980..8393
                     /gene_functions="biosynthetic (rule-based-clusters)
                     bacteriocin: TIGR03798"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg426_8"
                     /sec_met_domain="TIGR03798 (E-value: 2.9e-13, bitscore:
                     39.4, seeds: 22, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQLNIQSFKALDVSAEELKLQKAQQVIDELFMAANSNQRLFEQL
                     KAAISPENLVEIAVRQGYELTVADLERLHHYDQEQAQLNSDELDDDELSEQELELVAGG
                     CGFIQGLSKISFWMKNRSGKQYFGPMSYKRGQS"
     CDS             8390..10912
                     /locus_tag="ctg426_9"
                     /transl_table=11
                     /translation="MKTDSFLGKCSPLLWSSCLILGGALLNTDTTSAQLIPDATLGNES
                     SVVTPNVNINGLTSDQIDGGATRDANLFHSFGQFNVGEGRGVYFSNPTGIERILTRVTG
                     GNASNILGTLGVLGNADLFLINPNGIIFGAGSQLDLRGSFIGSTANSIQFADGLEFSAT
                     NPQTLPLLTIKVPLGLQYAANPGGIQVQGLGNQVIIDPQTFVFIGVDGKGLEVEQNQTL
                     ALVGGEVALSGGNLTAKGGTLELGSVQEGLVTLTPTNPGWALSYQGVENFQDILLSQGA
                     MINTSGPTPGRIQVQGRRVTLSDGSGLVATNLGIGNGENVTITASELIELSGTNPLNGL
                     PSFLFSGTTTAGKGGGVTLTTERLRLRDGAQVSSGTAGSGSAGMLSVNASQSVELIGVS
                     IPDLFSSGLFSSSSFAATGDAGNLTINTEQFILRDGATVSSETSGAGRGGDLTINASRS
                     VELTVTNPNGFPTSLSTATRGSGNAGNLTINTGRLIVRDGAQAASSTSSQGSGGNLSVN
                     AEESVEIIGTSANSASGLFASAIIGDGAGGDLRITTPRLIVRDGALLSVSNFQSRNLAP
                     PGTGPAGNLEIEAATIRLENQGVITAAAAGGDQGNITLDSQDIQMRRQSAITTNATGPS
                     AGGNITLNTDTLVALDNSDITANATNSQGGRVIVNAQGIFGTQFRPQLTIESDITASSD
                     LGAEFSGIVEINTPDADPSSGLVELSTTVVDVEGLVAQNLCTAKQAGSSFVISGRGGLP
                     TSPNDPLTDEVVVVEWSQPSTEVSSGGVSHPPSTDSGQRKNRVIRQIQGWFVAADGTVI
                     LTDAAPTVTPQSPALTHPGCVPPRMSLQ"
     CDS             11089..11349
                     /locus_tag="ctg426_10"
                     /transl_table=11
                     /translation="MTISTVNFNCVHLLIILAFSPVAAPVSAQMGEFADTRLQPEIQHF
                     PLLLDTFDPPKSPMEQKAKHPLVSPMEQKAKHPLVSPMEQKA"
ORIGIN
        1 aggggggtaa gggggacttt tatctactgt actttattac agcgcaaagc gctgtaaagg
       61 gggtggctaa cccggatttg ggaggaaagg ttgatctgag agttgtcatc ctcactctta
      121 acctggtttc taggaataat tgaccgagag aacggtaata atatagctga aaaaagggta
      181 atgctattcc accctaatta aatacagatt agctgactaa ttccacagca ataccgaagg
      241 cagtaaatcg ggatgcgcta atctcaaaaa ttggtaacca atcccggctg tgccttgaaa
      301 aaaacccgga ttgtaaacgt cttgaggaaa ctggggaaat agatgaaacc ctcccacttg
      361 ttttgcccgt ctcacgatcc agttagcttg ctttttaaca gtttctacta aatcggggcg
      421 caacaatttt tgtgccgcga ctagcagtac ctccatccga ccacaattcc cacagcagag
      481 gtggtctata ttgtgccagc taaactgtcg ggtagtatct aaggcgatcg ctatctcggc
      541 tcggatatct ggtgtatcca aactcgccaa acttcccaaa cgcgctaaac caatgccagg
      601 agcgccgtga caccagctag tcatataggt tggcttgcca tcaatcaggg cataagaccg
      661 caagtcgagc caatttccct gagtggggga aaacagatgc cgttcgtagg cgatcgcatc
      721 ctcagcggct ttccgaaaaa cgacctcttg agtcacttcg tacaagcgca gcaaggcata
      781 ggcaataccc gcagcaccat gggaaaatcc tgttaatggc ttttcggctc cagttgccca
      841 tgttttgaag cccgtttcgc tgatcacccg atgattgagc agatgctcac cacagcttat
      901 ggcttgagct aggatacccg aatcagccgt tacctgatgc aacgtgagta agccgagaat
      961 cgctcccgcc gctccagcca caaggtcaaa ctgctgatct gccgcaatgc gatcgcgtgt
     1021 gattaaacag gcggcttgtt tggcatctgc taacagcgtt ccatccccta gaaactgact
     1081 aattcgtacc agtgagtaaa caatagaccc caatccggcg gcacccccaa tacccagttg
     1141 ggtaactgtt tgccgcgact cagagtcaga atccggtaaa atccggcgca ggggttgtaa
     1201 agcacccaga cacaaatcac gccactcatt gttgccagtt attttcgtca atgcggcgag
     1261 gaataaggct attccagagc aaccgtcata taaactattc ccgattggct ggagttgaaa
     1321 acgatttgtc tggggtaaga aaccgagtcc aatccaggta gcactaccgt cagtagcttg
     1381 aatggctcgt cgctgcaaat cttgggcaat ttgtattgcc tgctgcaccg attcttcctc
     1441 agaaatgggg gaaacctgat catctagaac agagatggca gctgactttt cacgccattt
     1501 agaacaatcg atatcaaacc taacccgaac gccactgact ttagagtttg tagtaagcgc
     1561 tttagcgctt ctggcactaa agtgcctact acgaactttt atatcagagg tggcagtatt
     1621 tggttcacca accaccaata aagaactccg gatgatggca acttgttcag ctaaatcatc
     1681 ctgattcagg cgctggatag tcgcaatcat ctgggtataa ctgggttggg cgaagcatgg
     1741 caccatcatt tcacctttca ccactggcaa ggcatcacta tctgaatcag cggcaaaata
     1801 aggaatgtct aactgttcca gcgtctgtag ttctgcctgg agaatcctcc accaaggatg
     1861 ctttaaatct gtccccagaa acgctctgca cagaacctcc agttcaatac tgtgatctac
     1921 accatcccgc agatatttag gatgcagcga tttttgcagt acggaggcat aaacttgggt
     1981 gggacgaaat agacaacgca ctcgctgatg ggataaagca gccagggggc tatccgttgc
     2041 caggagtgcc tcccggtgtg cgagcaaaaa ccgatactga tgctcaaagc catccacgag
     2101 ttcgttaaca tactcctttg gggcttgtat aactcctgcc agggagggtg cattggtttg
     2161 acttgacaat tgggcagttt catgggttaa aaccatgcga tcggtgttaa tgttctccca
     2221 cttcggcatc tgataggatg tttcctgatt gccaaatcct accaagccac ttggatcata
     2281 agcggttcgt ttatctgacc ccagatgcca atgtggcaat aaacctgtcc gcatcacgga
     2341 atccatcaat cgccgctgcg ccagggatac agcctcgact ccctctttcc tggctgaacc
     2401 tgcaatttcc tggaatgggt ggtgcatcaa tgtttccaaa tccaccaaaa cggggtgttc
     2461 accgcaggca attacgtttt catggtggca gtcatttgcc cccaaaacat acagcaaaca
     2521 tagcaattga ccagcccgct ggtaataacg cttgatttct gcttggtttt gacaaggcaa
     2581 atattcgaca aactctaccc aaccataagt ggcgcgattg aggactttga gtaatttaaa
     2641 cggttgtaga gacgcgaaac ctggcgactc gataaaatgc tgattacacc aatttaggac
     2701 gttaaaataa gccacatcca agcttaagtc tttaggttta tagatcagtt tcaaacccga
     2761 tgtaaagctt acctcaatca cagatcgtcc ctgattgtga ggatcacttt tacaggggtt
     2821 gatcctatcg acttgaccta attcaatgtc tggctggaat gtttgctgaa tagttgacca
     2881 gtctgttgtt aatcgctgga taaattccca tgtggcatcc acccaaaaat ctgttactgt
     2941 tgctactaat cgcgccaaga cggggtagtc ttgaaaaaat gccagtagcc cttcgccttg
     3001 gaggatatgt tggataaatg cttgataatg agtgttggta taactatttt gtaattgtcc
     3061 cagtaatcga gatagagcgg attgtcgctt cgcccgaaat gctgagaatt tcaattccat
     3121 tgaggatgaa cagaaactgg atagtgagac taaaagactc cgctcaaggt tggcacaagc
     3181 tgcggctgtt aagttagggt gaatggcact gaaataagca ttatcgcatc gccgaaacct
     3241 ttgatatccc gtagggtggg cattgcccac cagctttaat tcagtggcat tcaagctagg
     3301 gtaattatca cccgttaggg cagttaattt atctctggca acttgaataa agggcaggaa
     3361 aatttcttca aagggaatgg gattatcggg ggcgagaaaa ctataggttt ttcccggttc
     3421 tagagtttct atggggatgg atgcggcggc ttcaattccg gcttggaagg tttctaccca
     3481 ggcgggtaaa ttctgagtac cgctgaggga aaaatcaccc agaagacggt taatggtgct
     3541 gagatttatg ttatcccaag caagccgctt ctgaaatttt tctaggtctc cttgtgcagc
     3601 cgtttgacac cacttttcaa gtctggactt aacacgagta tctgcatcag aaggattact
     3661 ggatatttca ccagtgacta aacgctctgt aaggctgcaa gcctgctcga caattctgac
     3721 cagttctggt tgtaaattgg tcattggtca aaacactgat ttcacggatt tattggcgag
     3781 atagggttag ggatgtgaga gcttattgac actgattaca ccgaaaagtc agttctctca
     3841 tcaagagatg atgattagga ttttaaggtg tcattggtca ttggtcaaaa cactgatttc
     3901 acggatttat tggagagata gggttaggga tgtgagagct tattgacact gattacaccg
     3961 aaaagtcagt tctctcatca agagatgatg attaggattt taaggtgtca attcatcgta
     4021 cccactaata atgaatgaaa taggcgagaa tggattgatg aatttttctc tcttgattga
     4081 tggatttttg gttctgtgtt gggctaggcg atacgttcct tcggaacacg cttcgcgatc
     4141 gcgcttcatc gaccaaacaa ttttttgagt ccccccacac tcttgggttt ctcatagata
     4201 tgatccacaa tcctgcgtat ttctttagag atataatgat ctggataacg caggcagaac
     4261 aaatcgctgc tctgtaactc catcatttct tcacagttag gcaagactcc tgctactgtt
     4321 gcattatagg ttgtttctac ttgttgccgg actgagttga gatcgaactt ctgtggtact
     4381 ctgttaacca ctagaagtag cttggctacc ttcaacttcc gagccacatc gacagttaca
     4441 gccgtccctt ggaagtcttg acgatctgga cgcaaaatga tcagcaggat gttggaaatt
     4501 gtcaccgaca ggagggtttc ttcgttaatt ccaggatgag tatcaataaa taggtagtct
     4561 agctctaggg agctaactag ctttttaaac ccattattga gcaaggctac gttgtatccc
     4621 tcacgcagga tacggctaat ttcaccgata ttcatgctgg atggaatcag aaacaatttg
     4681 ccctgattct tggttacttc aggaggactg acatcataag ccgtctcttc aaccccgcag
     4741 cgattccaca ggtaatcatt cagggttcgg tttatcttac tttggtctat accaaaaaga
     4801 acgtgaatcc ctggcgactg gatatccgta tcgataatcc ccacccgtag tccctggctg
     4861 gctgtggtaa ccgcgacatt ggctgtggtg ttcgatttcc cagttccacc tcgaaatgaa
     4921 tgaatagaga caattttcga cataacgctc ctttaaccct ctccttttgg ggtctattgc
     4981 ttaagttttg atgggtggca aaactataat tttatagcta ttaaagcctg attaaactaa
     5041 ctaacccatc aaaatcaata tggaatataa ttgatttttc tgtcacagga tttatctaaa
     5101 aattatcgca tatttatacg tctatgtgtt aataatataa ttaagatgag caaaattttc
     5161 cagcatctga caagaataaa ttttcagggc ggttggacta gagcaaatgg ctaccgaccc
     5221 tgagttgaat gttgcacacc ccaaacaaga ccttttgccc aaaaagcaac taaaagggta
     5281 acaagcacta cggcgatgca acaaaaatta actgtgtaag aggtctgaca ggaaaatggt
     5341 aagtaataag ttttctttac atcgcatagc actcgtggcg ttatttgtag agctattgac
     5401 cacgagtagt ttcccaatgc tggctcaggg gcgatcgctc aatcaagatg ggcttactcc
     5461 ctggaaaatc agcactcctc taacccactt tcctgagaat caggtagaga agtctccgac
     5521 tctccacgct caatcaatac ggtttcccac tacaggaaaa cctcgtcgcc gccgatcagc
     5581 ggcagtgcga ggaggcacag aagaggcggt agtaccaaat agctgtggca actctagcga
     5641 tgaacagatc gtcgctttgc tgcctccaac agagccagtg cgaactgtgg cagagcatcc
     5701 cacgattttg gtgtatctcc ctgaaaatac tgccaagcaa gccgagtttt acctgaaaga
     5761 ggctgacaac gatgagatag tctatgaaac aactgttacg cttccgggtg attccggaat
     5821 tgttagcgtc cctctcccag ataacggaac gttgccagcg ttagaggtgg gaaagacgta
     5881 tacttggcat ttctttgtga tttgtaatga gcaagatccg accaatgagc cttatgttga
     5941 gggacagata gaacgggttg aacctagccc aaacttggtg gctgagttgg aaaatgcgtc
     6001 actgcgcgat cgcgccgcca tttatgcgga agccgggatt tggtatgatt gcctcaatag
     6061 cctcgctcag ctacgtcgtt ctgctcccaa cgatagcgcg atcgcgtcgg attgggcagc
     6121 attgttagag tctgttggac tagatacaat ttcccaaaaa cctctgattt cttctagtgg
     6181 ttcacccaat taattttgat ggctaactct gcttattgtt gccattagtc cttgttcttg
     6241 gagtcaccgt ttaacgctat cttttttagc aggaggcgca ctgtttcagc gctgatgctc
     6301 tccaccaact ggagttgtac taacttttca gcgagcaatt gcgttgtcca acagtccttt
     6361 ccaggtggcg gtttactgga agcggtagcg attaagaact cttcggtttt tttgtctaat
     6421 ttcttaactg ctcctggacg agggcgttcg tttaaagcca agtctaaccc cccttccaca
     6481 aattttttac gggtgcgctc tactgttgcc acccccaaat gcagcatagt agcgatttcc
     6541 tcgtctttat gtccagcatc cgttaggagt aagatttggg cacggcgtag ctttcgagct
     6601 gatatcttgc ctttttttgt cagtttgatt agctcttgcc tttcagtttg gcttaattgg
     6661 acttggtgct tttgaatcat cacggttaat tggcatggac tctatagata aaacggcgat
     6721 ttgaggactg gaatgtgatc gtgaactgga ataccactga gctgtctatc cttctcttca
     6781 gtcatcaaaa tcaattttgc aaatcactat tttatccctg acttaaaaac actaatgact
     6841 tcattagtca tcaaaaataa tttgcacaat tctctttgtg tatattttaa tcacaaaggt
     6901 gtatgatatg gcaagataag tgtatagtag atagttatgt aatgcattta gacagcctta
     6961 ccataaaatc agcgaatgga gttgtcttct ggtggtgttc gctattcccg ccagacgatg
     7021 gttggcttaa aggcgacact tcttgtggca aaggctacag aagtaaagcg gtataaatgc
     7081 aagttggtta actctcacag ccagattccc ccccgatacc taggaggttt ttatgtcaca
     7141 gtcaaatatc cagatcatgt cacctttgta ggttgggttg aggaacgaaa cccaacatgc
     7201 tttccctgga gttgggtaac gcttacgctc tacccaacct acgagaatat tttgtgcaaa
     7261 acttacatgt tcccggaggg ttttatgtca cagtcaaata tccagtcatt taacgctgaa
     7321 gacctatcag cggaggaatt acaactacaa aaagcgcagc aagtcataga tgaactgttt
     7381 atggctgccg aatcggatga gaagcttaat gagcaactcg aagcggcgat tagcccagaa
     7441 agcttggtgg aaatcgctac ccgtcaaggg tacaaattga cagtagcgga tttagaaatg
     7501 ctacatcatt atgaccaaga gcaagcacaa cttaactcgg atgagttgga tgatgatgaa
     7561 ctcagcgaac aagagctaga gctagtcgct ggtggtcgtg ctaaaggtct tacatctctt
     7621 actgcgcctc ctaagccggt tccgagtggt tttaatccct ctccgaaatc tcaagggttt
     7681 cctgttcctt ggtggccttg gtgagcttaa cagtggcata gcttgaggaa tttaccccat
     7741 aactagaaga tacttatgtt acagccagag atccaagcac ttaaagccga aaacttatca
     7801 acttttaaca gtgatgagga tgatgaactc agtgaacaag agttagagct agtcgctggt
     7861 ggtaatggct ttaatccacc aacatcagaa cctggttggg ttcacgatcc aacttgccct
     7921 aattacagag ctggcatgga gcaataacta agcagttgcc cgatacctag gaggtgttta
     7981 tgtcacagtt aaatatccag tcatttaaag cattagacgt atcagcggag gaattaaaac
     8041 tacaaaaagc gcagcaagtc atagatgaac tgtttatggc ggctaactcg aatcagaggc
     8101 tctttgagca actcaaagcg gcgattagcc cagagaactt ggtcgaaatc gctgtccgtc
     8161 aagggtacga attgacagta gcagacttag aaaggctaca tcattatgac caagaacaag
     8221 cacaacttaa ctcggatgag ttggatgatg atgaactcag tgaacaggag ctagagctag
     8281 tcgctggtgg atgtggcttt attcaaggat tatcaaaaat ttccttttgg atgaaaaatc
     8341 gttctgggaa acagtacttt ggcccgatgt catataaacg cggtcagtca tgaaaaccga
     8401 tagctttttg gggaaatgtt ctcctttatt gtggagcagt tgtttaatcc ttggtggagc
     8461 gctgctaaac acagatacta cctcagcaca gctcatcccc gatgccactc tcggtaacga
     8521 aagctcagtc gttactccta atgtcaatat caatggttta accagtgacc aaattgatgg
     8581 cggagcaacc agagatgcta acctgttcca cagttttgga caattcaatg tcggggaagg
     8641 caggggagtc tatttctcca atcccacagg gattgaacgg attctcacgc gagtcactgg
     8701 gggaaatgct tctaatatcc tgggaacctt gggagtttta ggcaacgctg acctattttt
     8761 aattaacccc aatggaatta tctttggtgc aggctctcaa ctcgacctga gaggttcatt
     8821 tattggcagt acggcgaata gcatccaatt tgccgatggt ctagaattta gtgctaccaa
     8881 cccccaaacc ctacccttac taacgattaa agttcccttg ggcttacaat atgcagccaa
     8941 tccgggaggg attcaagtgc aggggttggg caaccaagtc atcattgatc cccaaacctt
     9001 tgtattcatt ggcgtagatg gaaaaggtct tgaagtagag cagaatcaaa ccttagcctt
     9061 agtgggcggt gaggtagccc tttctggcgg aaatctaacc gcaaaaggcg gaactctgga
     9121 gttgggaagt gtacaggagg ggctagtcac ccttacccca accaatccgg gctgggcatt
     9181 gagctatcaa ggcgtggaaa atttccaaga tatcctgctg tcccaagggg ctatgattaa
     9241 caccagtggt ccgacaccgg gaagaattca ggtacaagga cggcgcgtca ccctctccga
     9301 cggttcagga ctggtggcaa ctaacctggg aattggaaac ggcgagaacg taactattac
     9361 tgcctcagag ttaatcgagt tgagtgggac aaatcctctc aatggtcttc ctagcttctt
     9421 gttttctggt acaacaacgg ctggaaaggg cggtggcgtg accctgacca cagagcggtt
     9481 gcggctgcgg gatggggcgc aagtctcatc tggtacggct ggttcgggca gtgcgggtat
     9541 gctcagcgtg aatgcttcgc agtccgtaga actgattgga gtctcaatcc ctgacctgtt
     9601 ttccagtggt ttatttagca gcagtagttt tgccgccact ggagacgcgg ggaatttaac
     9661 cattaacacc gagcaattca ttctccggga tggggcaaca gttagcagtg aaacctctgg
     9721 tgcgggtcgt gggggagatt tgactataaa cgcttcgcgc tctgtggagc taactgtcac
     9781 aaacccaaat ggctttccca ccagtttatc gacggcgact cgaggcagtg gaaatgcggg
     9841 caacttgacg attaatacag gacgcttgat tgtccgggat ggcgcccaag ccgccagttc
     9901 gacaagtagt caaggttctg ggggaaacct gagtgtgaac gccgaggagt cggtagaaat
     9961 aataggtacg tcagccaatt ctgccagcgg cttgtttgcc tcggcgatta tcggtgatgg
    10021 agccgggggc gacttgagga ttactactcc tcggttaatt gtccgggatg gggcattgct
    10081 cagtgtgagt aacttccaaa gccgcaacct ggcaccgccg ggaacgggtc ctgcgggcaa
    10141 ccttgagata gaggctgcca caatccgact ggaaaatcaa ggggtgatca cagccgctgc
    10201 tgctggagga gaccagggaa atattaccct ggattcccaa gacatccaga tgcgccgaca
    10261 gagtgccatc accacgaacg ccaccggacc gagcgcgggt ggtaatatca cgctcaacac
    10321 cgatacctta gtcgccctgg acaatagcga catcacggcg aatgccacga atagtcaagg
    10381 tgggcgcgtc atcgtcaatg cacaaggcat cttcggcact cagttccgtc cccaactcac
    10441 catagaaagc gacatcaccg ccagttcgga cttgggggct gaattcagcg gcattgtgga
    10501 aattaacacc cctgatgctg atccgagttc tggattagtc gaattatcaa caactgttgt
    10561 tgatgtcgaa ggcttagtgg cacaaaatct ctgtacagcg aaacaagcgg gtagttcctt
    10621 tgtcatcagc ggacgcgggg gtttacccac cagtccgaat gacccgttga ctgatgaagt
    10681 tgtggtggtg gagtggtctc aaccgagtac tgaggtgtcg tctggagggg tgagtcatcc
    10741 gccatcaacc gatagtggac aacggaaaaa tcgggtgatt cggcaaatac aaggctggtt
    10801 tgtcgcggct gatgggacag ttatcctgac tgacgccgca cctactgtga caccgcagag
    10861 tcctgccttg actcaccccg gttgtgttcc acctagaatg tctctccagt agagacgcgc
    10921 catggcggta gagacgcgcc atggcgcgtc tctacaaaag gggggatttg gggggatttt
    10981 gttacagtac accccacacc taacccccac gtttttgatg ccgtgaaaac tcagttcaat
    11041 ttttcccaaa acccaaaacc cttacgaatg acaaatgaca aatgacgaat gacgatctca
    11101 acggttaact ttaattgtgt ccacctactt atcattcttg ctttcagccc agtggcggca
    11161 cccgttagcg cccaaatggg agaattcgcg gatacgaggt tacaaccaga gatacagcac
    11221 tttccgctct tattggatac gtttgatccc cctaaatccc ccatggaaca aaaagcgaag
    11281 catccgctgg tctcccccat ggaacaaaaa gcgaagcatc cgctggtctc ccccatggaa
    11341 caaaaagcga
//
