LOCUS       c00738_3300000..       10422 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300000354.a:ElkS_mat_CD6ADRAFT_1000462.
ACCESSION   c00738_3300000..
VERSION     c00738_3300000..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 05:26:13
            Original ID  :: 3300000354.a:ElkS_mat_CD6ADRAFT_1000462
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10422
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..2808)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide: DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070:lanthionine synthetase C family protein (Score:
                     604.2; E-value: 7.4e-183)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg738_1"
                     /sec_met_domain="LANC_like (E-value: 1.8e-20, bitscore:
                     62.2, seeds: 47, tool: rule-based-clusters)"
                     /sec_met_domain="DUF4135 (E-value: 1.7e-119, bitscore:
                     388.5, seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTNLQPELVRIVEQACSLTERLVTGEISSNPSDADTRVKSRLEKW
                     CQTAAQGDLEKFQKRLAWDNINLSTINRLLGDFSLSGTQNLPAWVETFQAGIEAAASIP
                     IETLEPGKTYSFLAPDNPIPFEEIFLPFIQVARDKLTALTGDNYPSLNATELKLVGNAH
                     PTGYQRFRRCDNAYFSAIHPNLTAAACANLERSLLVSLSSFCSSSMELKFSAFRAKRQS
                     ALSRLLGQLQNSYTNTHYQAFIQHILQGEGLLAFFQDYPVLARLVATVTDFWVDATWEF
                     IQRLTTDWSTIQQTFQPDIELGQVDRINPCKSDPHNQGRSVIEVSFTSGLKLIYKPKDL
                     SLDVAYFNVLNWCNQHFIESPGFASLQPFKLLKVLNRATYGWVEFVEYLPCQNQAEIKR
                     YYQRAGQLLCLLYVLGANDCHHENVIACGEHPVLVDLETLMHHPFEEIAGSARKEGVEA
                     VSLAQRRLMDSVMRTGLLPHWHLGSDKRTAYDPSGLVGFGNQETSYQMPKWENINTDRM
                     VLTHETAQLSSQTNAPSLAGVIQAPKEYVNELVDGFEHQYRFLLAHREALLATDSPLAA
                     LSHQRVRCLFRPTQVYASVLQKSLHPKYLRDGVDHSIELEVLCRAFLGTDLKHPWWRIL
                     QAELQTLEQLDIPYFAADSDSDALPVVKGEMMVPCFAQPSYTQMIATIQRLNQDDLAEQ
                     VAIIRSSLLVVGEPNTATSDIKVRSRHFSARSAKALTTNSKVSGVRVRFDIDCSKWREK
                     SAAISVLDDQVSPISEEESVQQAIQIAQDLQRRAIQATDGSVTWIGLHFLPQANRFQLQ
                     PIGNSLYDGCPGIALFLGGLTKITGDNQWRDLCLGALQPLRRILLDSDSKSRQKLTRLG
                     IGGAAGLGSIVYSLVRISQFLGDETLLADAKQVASLITRDRIAADQQFDLVAGAAGAIL
                     GLLTLH"
     protocluster    1..10422
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[0:2808](-)"
                     /cutoff="20000"
                     /detection_rule="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C) or cds(LANC_like and (Pkinase or DUF4135)))
                     and not (YcaO or TIGR03882))"
                     /neighbourhood="10000"
                     /product="lanthipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(1..2808)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C) or cds(LANC_like and (Pkinase or DUF4135)))
                     and not (YcaO or TIGR03882))"
                     /neighbourhood="10000"
                     /product="lanthipeptide"
                     /protocluster_number="1"
     cand_cluster    1..10422
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C) or cds(LANC_like and (Pkinase or DUF4135)))
                     and not (YcaO or TIGR03882))"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03603 or TIGR03604 or TIGR03651 or
                     TIGR03678 or TIGR03693 or TIGR03798 or TIGR03601 or
                     TIGR03602 or TIGR03795 or TIGR03793 or TIGR03975 or DUF692
                     or TIGR01193)"
                     /kind="neighbouring"
                     /product="lanthipeptide"
                     /product="bacteriocin"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     region          1..10422
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /contig_edge="True"
                     /product="lanthipeptide"
                     /product="bacteriocin"
                     /region_number="1"
                     /rules="((LANC_like and (Lant_dehydr_N or Lant_dehydr_C) or
                     cds(LANC_like and (Pkinase or DUF4135))) and not (YcaO or
                     TIGR03882))"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03603 or TIGR03604 or TIGR03651 or TIGR03678 or
                     TIGR03693 or TIGR03798 or TIGR03601 or TIGR03602 or
                     TIGR03795 or TIGR03793 or TIGR03975 or DUF692 or
                     TIGR01193)"
                     /tool="antismash"
     protocluster    1349..10422
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[6348:7457]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03603 or TIGR03604 or TIGR03651 or
                     TIGR03678 or TIGR03693 or TIGR03798 or TIGR03601 or
                     TIGR03602 or TIGR03795 or TIGR03793 or TIGR03975 or DUF692
                     or TIGR01193)"
                     /neighbourhood="5000"
                     /product="bacteriocin"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      6349..7457
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03603 or TIGR03604 or TIGR03651 or
                     TIGR03678 or TIGR03693 or TIGR03798 or TIGR03601 or
                     TIGR03602 or TIGR03795 or TIGR03793 or TIGR03975 or DUF692
                     or TIGR01193)"
                     /neighbourhood="5000"
                     /product="bacteriocin"
                     /protocluster_number="2"
     cand_cluster    1349..10422
                     /candidate_cluster_number="2"
                     /contig_edge="True"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03603 or TIGR03604 or TIGR03651 or
                     TIGR03678 or TIGR03693 or TIGR03798 or TIGR03601 or
                     TIGR03602 or TIGR03795 or TIGR03793 or TIGR03975 or DUF692
                     or TIGR01193)"
                     /kind="single"
                     /product="bacteriocin"
                     /protoclusters="2"
                     /tool="antismash"
     CDS             complement(3210..4007)
                     /gene_functions="other (smcogs) SMCOG1157:hypothetical
                     protein (Score: 133.6; E-value: 1.5e-40)"
                     /gene_kind="other"
                     /locus_tag="ctg738_2"
                     /transl_table=11
                     /translation="MSKIVSIHSFRGGTGKSNTTANVAVTTASQGLRVGIIDTDIQSPG
                     IHVLFGIDQSKINRTLNDYLWNRCGVEETAYDVSPPEVTKNQGKLFLIPSSMNIGEISR
                     ILREGYNVALLNNGFKKLVSSLELDYLFIDTHPGINEETLLSVTISNILLIILRPDRQD
                     FQGTAVTVDVARKLKVAKLLLVVNRVPQKFDLNSVRQQVETTYNATVAGVLPNCEEMME
                     LQSSDLFCLRYPDHYISKEIRRIVDHIYEKPKSVGGLKKLFGR"
     CDS             complement(4262..4333)
                     /gene="allorf_04262_04333"
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="allorf_04262_04333"
                     /protein_id="allorf_04262_04333"
                     /tool="antismash"
                     /transl_table=1
                     /translation="LLFGQKVLFGVCNIQLRVGSHLL"
     CDS_motif       complement(4304..4333)
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: LLFGQKVLFG"
                     /aSTool="lanthipeptides"
                     /prepeptide="leader"
                     /tool="antismash"
                     /locus_tag="allorf_04262_04333"
     CDS_motif       complement(4262..4303)
                     /predicted_class="Class II"
                     /core_sequence="VCNIQLRVGSHLL"
                     /leader_sequence="LLFGQKVLFG"
                     /monoisotopic_mass="1432.8"
                     /aSTool="lanthipeptides"
                     /prepeptide="core"
                     /tool="antismash"
                     /leader_location="[4303:4333](-)"
                     /peptide="lanthipeptide"
                     /score="-5.20"
                     /molecular_weight="1433.7"
                     /locus_tag="allorf_04262_04333"
     CDS             4400..5257
                     /locus_tag="ctg738_3"
                     /transl_table=11
                     /translation="MVSNKFSLHRIALVALFVELLTTSSFPMLAQGRSLNQDGLTPWKI
                     STPLTHFPENQVEKSPTLHAQSIRFPTTGKPRRRRSAAVRGGTEEAVVPNSCGNSSDEQ
                     IVALLPPTEPVRTVAEHPTILVYLPENTAKQAEFYLKEADNDEIVYETTVTLPGDSGIV
                     SVPLPDNGTLPALEVGKTYTWHFFVICNEQDPTNEPYVEGQIERVEPSPNLVAELENAS
                     LRDRAAIYAEAGIWYDCLNSLAQLRRSAPNDSAIASDWAALLESVGLDTISQKPLISSS
                     GSPN"
     CDS             complement(5289..5744)
                     /gene_functions="other (smcogs) SMCOG1229:transposase
                     (Score: 83.8; E-value: 2e-25)"
                     /gene_kind="other"
                     /locus_tag="ctg738_4"
                     /transl_table=11
                     /translation="MIQKHQVQLSQTERQELIKLTKKGKISARKLRRAQILLLTDAGHK
                     DEEIATMLHLGVATVERTRKKFVEGGLDLALNERPRPGAVKKLDKKTEEFLIATASSKP
                     PPGKDCWTTQLLAEKLVQLQLVESISAETVRLLLKKIALNGDSKHKD"
     CDS             5799..5885
                     /gene="allorf_05799_05885"
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="allorf_05799_05885"
                     /protein_id="allorf_05799_05885"
                     /tool="antismash"
                     /transl_table=1
                     /translation="VIVNWNTTELSILLFSHQNQFCKSLFYP"
     CDS_motif       5799..5846
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: VIVNWNTTELSILLFS"
                     /aSTool="lanthipeptides"
                     /prepeptide="leader"
                     /tool="antismash"
                     /locus_tag="allorf_05799_05885"
     CDS_motif       5847..5885
                     /predicted_class="Class II"
                     /core_sequence="HQNQFCKSLFYP"
                     /leader_sequence="VIVNWNTTELSILLFS"
                     /monoisotopic_mass="1492.7"
                     /aSTool="lanthipeptides"
                     /prepeptide="core"
                     /tool="antismash"
                     /leader_location="[5798:5846](+)"
                     /peptide="lanthipeptide"
                     /score="-4.90"
                     /molecular_weight="1493.7"
                     /locus_tag="allorf_05799_05885"
     CDS             complement(5999..6115)
                     /gene="allorf_05999_06115"
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="allorf_05999_06115"
                     /protein_id="allorf_05999_06115"
                     /tool="antismash"
                     /transl_table=1
                     /translation="LPQEVSPLSQPSSGGNSEHHQKTTPFADFMVRLSKCIT"
     CDS_motif       complement(6035..6115)
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: LPQEVSPLSQPSSGGNSEHHQKTTPFA"
                     /aSTool="lanthipeptides"
                     /prepeptide="leader"
                     /tool="antismash"
                     /locus_tag="allorf_05999_06115"
     CDS_motif       complement(5999..6034)
                     /predicted_class="Class II"
                     /core_sequence="DFMVRLSKCIT"
                     /leader_sequence="LPQEVSPLSQPSSGGNSEHHQKTTPFA"
                     /monoisotopic_mass="1275.7"
                     /aSTool="lanthipeptides"
                     /alternative_weights="1294.6"
                     /prepeptide="core"
                     /tool="antismash"
                     /leader_location="[6034:6115](-)"
                     /peptide="lanthipeptide"
                     /score="-6.40"
                     /molecular_weight="1276.6"
                     /locus_tag="allorf_05999_06115"
     CDS             6349..6768
                     /gene_functions="biosynthetic (rule-based-clusters)
                     bacteriocin: TIGR03798"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg738_5"
                     /sec_met_domain="TIGR03798 (E-value: 1.9e-13, bitscore:
                     39.8, seeds: 22, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQSNIQSFNAEDLSAEELQLQKAQQVIDELFMAAESDEKLNEQL
                     EAAISPESLVEIATRQGYKLTVADLEMLHHYDQEQAQLNSDELDDDELSEQELELVAGG
                     RAKGLTSLTAPPKPVPSGFNPSPKSQGFPVPWWPW"
     CDS             6820..7011
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg738_6"
                     /transl_table=11
                     /translation="MLQPEIQALKAENLSTFNSDEDDELSEQELELVAGGNGFNPPTSE
                     PGWVHDPTCPNYRAGMEQ"
     CDS_motif       6820..6927
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MLQPEIQALKAENLSTFNSDEDDELSEQELELVAGG"
                     /aSTool="lanthipeptides"
                     /prepeptide="leader"
                     /tool="antismash"
                     /locus_tag="ctg738_6"
     CDS_motif       6928..7011
                     /predicted_class="Class II"
                     /core_sequence="NGFNPPTSEPGWVHDPTCPNYRAGMEQ"
                     /leader_sequence="MLQPEIQALKAENLSTFNSDEDDELSEQELELVAGG"
                     /monoisotopic_mass="2946.3"
                     /aSTool="lanthipeptides"
                     /alternative_weights="2966.2"
                     /alternative_weights="2984.2"
                     /prepeptide="core"
                     /tool="antismash"
                     /leader_location="[6819:6927](+)"
                     /peptide="lanthipeptide"
                     /score="1.70"
                     /molecular_weight="2948.2"
                     /locus_tag="ctg738_6"
     CDS             7044..7457
                     /gene_functions="biosynthetic (rule-based-clusters)
                     bacteriocin: TIGR03798"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg738_7"
                     /sec_met_domain="TIGR03798 (E-value: 2.6e-13, bitscore:
                     39.4, seeds: 22, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQLNIQSFKALDVSAEELKLQKAQQVIDELFMAANSNQRLFEQL
                     KAAISPENLVEIAVRQGYELTVADLERLHHYDQEQAQLNSDELDDDELSEQELELVAGG
                     CGFIQGLSKISFWMKNRSGKQYFGPMSYKRGQS"
     CDS             7454..9976
                     /locus_tag="ctg738_8"
                     /transl_table=11
                     /translation="MKTDSFLGKCSPLLWSSCLILGGALLNTDTTSAQLIPDATLGNES
                     SVVTPNVNINGLTSDQIDGGATRDANLFHSFGQFNVGEGRGVYFSNPTGIERILTRVTG
                     GNASNILGTLGVLGNADLFLINPNGIIFGAGSQLDLRGSFIGSTANSIQFADGLEFSAT
                     NPQTLPLLTIKVPLGLQYAANPGGIQVQGLGNQVIIDPQTFVFIGVDGKGLEVEQNQTL
                     ALVGGEVALSGGNLTAKGGTLELGSVQEGLVTLTPTNPGWALSYQGVENFQDILLSQGA
                     MINTSGPTPGRIQVQGRRVTLSDGSGLVATNLGIGNGENVTITASELIELSGTNPLNGL
                     PSFLFSGTTTAGKGGGVTLTTERLRLRDGAQVSSGTAGSGSAGMLSVNASQSVELIGVS
                     IPDLFSSGLFSSSSFAATGDAGNLTINTEQFILRDGATVSSETSGAGRGGDLTINASRS
                     VELTVTNPNGFPTSLSTATRGSGNAGNLTINTGRLIVRDGAQAASSTSSQGSGGNLSVN
                     AEESVEIIGTSANSASGLFASAIIGDGAGGDLRITTPRLIVRDGALLSVSNFQSRNLAP
                     PGTGPAGNLEIEAATIRLENQGVITAAAAGGDQGNITLDSQDIQMRRQSAITTNATGPS
                     AGGNITLNTDTLVALDNSDITANATNSQGGRVIVNAQGIFGTQFRPQLTIESDITASSD
                     LGAEFSGIVEINTPDADPSSGLVELSTTVVDVEGLVAQNLCTAKQAGSSFVISGRGGLP
                     TSPNDPLTDEVVVVEWSQPSTEVSSGGVSHPPSTDSGQRKNRVIRQIQGWFVAADGTVI
                     LTDAAPTVTPQSPALTHPGCVPPRMSLQ"
     CDS             10153..10422
                     /locus_tag="ctg738_9"
                     /transl_table=11
                     /translation="MTISTVNFNCVHLLIILAFSPVAAPVSAQMGEFADTRLQPEIQHF
                     PLLLDTFDPPKSPMEQKAKHPLVSPMEQKAKHPLVSPMEQKAKHP"
ORIGIN
        1 atgtaacgtg agtaagccga gaatcgctcc cgccgctcca gccacaaggt caaactgctg
       61 atcagccgca atgcgatcgc gcgtgattaa actggcgact tgtttggcat ctgctaacag
      121 cgtttcatcc cctagaaact gactgattcg caccagtgag taaacaatag accccaatcc
      181 ggcggcaccc ccaataccga gtcgggtcag tttttgccgc gacttagagt cagaatccag
      241 caaaatccgg cgcaggggtt gtaacgctcc cagacacaaa tcacgccact gattgtcgcc
      301 agttattttc gtcaatccgc ctaagaataa ggctattcca gggcaaccgt catataaact
      361 atttccgatt ggctggagtt gaaaacgatt tgcctggggt aagaaatgga gtccaatcca
      421 ggtaacacta ccgtcagtag cttgaatggc tcgtcgctgc aaatcttggg caatttgtat
      481 tgcctgctgc accgattctt cctcagaaat gggggaaacc tgatcatcta gaacagagat
      541 ggcagctgac ttttcacgcc atttagaaca atcgatatca aacctaaccc gaacgccact
      601 gactttagag tttgtagtaa gcgctttagc gcttctggca ctaaagtgcc tactacgaac
      661 ttttatatca gaggtggcag tatttggttc accaaccacc aataaagaac tccggatgat
      721 ggcaacttgt tcagctaaat catcctgatt caggcgctgg atagtcgcaa tcatctgggt
      781 ataactgggt tgggcgaagc atggcaccat catttcacct ttcaccactg gcaaggcatc
      841 actatctgaa tcagcggcaa aataaggaat gtctaactgt tccagcgtct gtagttctgc
      901 ctggagaatc ctccaccaag gatgctttaa atctgtcccc agaaacgctc tgcacagaac
      961 ctccagttca atactgtgat ctacaccatc ccgcagatat ttaggatgca gcgatttttg
     1021 cagtacggag gcataaactt gggtgggacg aaatagacaa cgcactcgct gatgggataa
     1081 agcagccagg gggctatccg ttgccaggag tgcctcccgg tgtgcgagca aaaaccgata
     1141 ctgatgctca aagccatcca cgagttcgtt aacatactcc tttggggctt gtataactcc
     1201 tgccagggag ggtgcattgg tttgacttga caattgggca gtttcatggg ttaaaaccat
     1261 gcgatcggtg ttaatgttct cccacttcgg catctgatag gatgtttcct gattgccaaa
     1321 tcctaccaag ccacttggat cataagcggt tcgtttatct gaccccagat gccaatgtgg
     1381 caataaacct gtccgcatca cggaatccat caatcgccgc tgcgccaggg atacagcctc
     1441 gactccctct ttcctggctg aacctgcaat ttcctcgaat gggtggtgca tcaatgtttc
     1501 caaatccacc aaaacggggt gttcaccgca ggcaattacg ttttcatggt ggcagtcatt
     1561 tgcccccaaa acatacagca aacatagcaa ttgaccagcc cgctggtaat aacgcttgat
     1621 ttctgcttgg ttttgacaag gcaaatattc gacaaactct acccaaccat aagtggcgcg
     1681 attgaggact ttgagtaatt taaacggttg tagagacgcg aaacctggcg actcgataaa
     1741 atgctgatta caccaattta ggacgttaaa ataagccaca tccaagctta agtctttagg
     1801 tttatagatc agtttcaaac ccgatgtaaa gcttacctca atcacagatc gtccctgatt
     1861 gtgaggatca cttttacagg ggttgatcct atcgacttga cctaattcaa tgtctggctg
     1921 gaatgtttgc tgaatagttg accagtctgt tgttaatcgc tggataaatt cccatgtggc
     1981 atccacccaa aaatctgtta ctgttgctac taatcgcgcc aagacggggt agtcttgaaa
     2041 aaatgccagt agcccttcgc cttggaggat atgttggata aatgcttgat aatgagtgtt
     2101 ggtataacta ttttgtaatt gtcccagtaa tcgagataga gcggattgtc gcttcgcccg
     2161 aaatgctgag aatttcaatt ccattgagga tgaacagaaa ctggatagtg agactaaaag
     2221 actccgctca aggttggcac aagctgcggc tgttaagtta gggtgaatgg cactgaaata
     2281 agcattatcg catcgccgaa acctttgata tcccgtaggg tgggcattgc ccaccagctt
     2341 taattcagtg gcattcaagc tagggtaatt atcacccgtt agggcagtta atttatctct
     2401 ggcaacttga ataaagggca ggaaaatttc ttcaaaggga atgggattat cgggggcgag
     2461 aaaactatag gtttttcccg gttctagagt ttctatgggg atggatgcgg cggcttcaat
     2521 tccggcttgg aaggtttcta cccaggcggg taaattctga gtaccgctga gggaaaaatc
     2581 acccagaaga cggttaatgg tgctgagatt tatgttatcc caagcaagcc gcttctgaaa
     2641 tttttctagg tctccttgtg cagccgtttg acaccacttt tcaagtctgg acttaacacg
     2701 agtatctgca tcagaaggat tactggatat ttcaccagtg actaaacgct ctgtaaggct
     2761 gcaagcctgc tcgacaattc tgaccagttc tggttgtaaa ttggtcattg gtcaaaacac
     2821 tgatttcacg gatttattgg cgagataggg ttagggatgt gagagcttat tgacactgat
     2881 tacaccgaaa agtcagttct ctcatcaaga gatgatgatt aggattttaa ggtgtcattg
     2941 gtcattggtc aaaacactga tttcacggat ttattggaga gatagggtta gggatgtgag
     3001 agcttattga cactgattac accgaaaagt cagttctctc atcaagagat gatgattagg
     3061 attttaaggt gtcaattcat cgtacccact aataatgaat gaaataggcg agaatggatt
     3121 gatgaatttt tctctcttga ttgatggatt tttggttctg tgttgggcta ggcgatacgt
     3181 tccttcggaa cacgcttcgc gatcgcgctt catcgaccaa acaatttttt gagtcccccc
     3241 acactcttgg gtttctcata gatatgatcc acaatcctgc gtatttcttt agagatataa
     3301 tgatctggat aacgcaggca gaacaaatcg ctgctctgta actccatcat ttcttcacag
     3361 ttaggcaaga ctcctgctac tgttgcatta taggttgttt ctacttgttg ccggactgag
     3421 ttgagatcga acttctgtgg tactctgtta accactagaa gtagcttggc taccttcaac
     3481 ttccgagcca catcgacagt tacagccgtc ccttggaagt cttgacgatc tggacgcaaa
     3541 atgatcagca ggatgttgga aattgtcacc gacaggaggg tttcttcgtt aattccagga
     3601 tgagtatcaa taaataggta gtctagctct agggagctaa ctagcttttt aaacccatta
     3661 ttgagcaagg ctacgttgta tccctcacgc aggatacggc taatttcacc gatattcatg
     3721 ctggatggaa tcagaaacaa tttgccctga ttcttggtta cttcaggagg actgacatca
     3781 taagccgtct cttcaacccc gcagcgattc cacaggtaat cattcagggt tcggtttatc
     3841 ttactttggt ctataccaaa aagaacgtga atccctggcg actggatatc cgtatcgata
     3901 atccccaccc gtagtccctg gctggctgtg gtaaccgcga cattggctgt ggtgttcgat
     3961 ttcccagttc cacctcgaaa tgaatgaata gagacaattt tcgacataac gctcctttaa
     4021 ccctctcctt ttggggtcta ttgcttaagt tttgatgggt ggcaaaacta taattttata
     4081 gctattaaag cctgattaaa ctaactaacc catcaaaatc aatatggaat ataattgatt
     4141 tttctgtcac aggatttatc taaaaattat cgcatattta tacgtctatg tgttaataat
     4201 ataattaaga tgagcaaaat tttccagcat ctgacaagaa taaattttca gggcggttgg
     4261 actagagcaa atggctaccg accctgagtt gaatgttgca caccccaaac aagacctttt
     4321 gcccaaaaag caactaaaag ggtaacaagc actacggcga tgcaacaaaa attaactgtg
     4381 taagaggtct gacaggaaaa tggtaagtaa taagttttct ttacatcgca tagcactcgt
     4441 ggcgttattt gtagagctat tgaccacgag tagtttccca atgctggctc aggggcgatc
     4501 gctcaatcaa gatgggctta ctccctggaa aatcagcact cctctaaccc actttcctga
     4561 gaatcaggta gagaagtctc cgactctcca cgctcaatca atacggtttc ccactacagg
     4621 aaaacctcgt cgccgccgat cagcggcagt gcgaggaggc acagaagagg cggtagtacc
     4681 aaatagctgt ggcaactcta gcgatgaaca gatcgtcgct ttgctgcctc caacagagcc
     4741 agtgcgaact gtggcagagc atcccacgat tttggtgtat ctccctgaaa atactgccaa
     4801 gcaagccgag ttttacctga aagaggctga caacgatgag atagtctatg aaacaactgt
     4861 tacgcttccg ggtgattccg gaattgttag cgtccctctc ccagataacg gaacgttgcc
     4921 agcgttagag gtgggaaaga cgtatacttg gcatttcttt gtgatttgta atgagcaaga
     4981 tccgaccaat gagccttatg ttgagggaca gatagaacgg gttgaaccta gcccaaactt
     5041 ggtggctgag ttggaaaatg cgtcactgcg cgatcgcgcc gccatttatg cggaagccgg
     5101 gatttggtat gattgcctca atagcctcgc tcagctacgt cgttctgctc ccaacgatag
     5161 cgcgatcgcg tcggattggg cagcattgtt agagtctgtt ggactagata caatttccca
     5221 aaaacctctg atttcttcta gtggttcacc caattaattt tgatggctaa ctctgcttat
     5281 tgttgccatt agtccttgtg cttggagtca ccgtttaacg ctatcttttt tagcaggagg
     5341 cgcactgttt cagcgctgat gctctccacc aactggagtt gtactaactt ttcagcgagc
     5401 aattgcgttg tccaacagtc ctttccaggt ggcggtttac tggaagcggt agcgattaag
     5461 aactcttcgg tttttttgtc taatttctta actgctcctg gacgagggcg ttcgtttaaa
     5521 gccaagtcta accccccttc cacaaatttt ttacgggtgc gctctactgt tgccaccccc
     5581 aaatgcagca tagtagcgat ttcctcgtct ttatgtccag catccgttag gagtaagatt
     5641 tgggcacggc gtagctttcg agctgatatc ttgccttttt ttgtcagttt gattagctct
     5701 tgcctttcag tttggcttaa ttggacttgg tgcttttgaa tcatcacggt taattggcat
     5761 ggactctata gataaaacgg cgatttgagg actggaatgt gatcgtgaac tggaatacca
     5821 ctgagctgtc tatccttctc ttcagtcatc aaaatcaatt ttgcaaatca ctattttatc
     5881 cctgacttaa aaacactaat gacttcatta gtcatcaaaa ataatttgca caattctctt
     5941 tgtgtatatt ttaatcacaa aggtgtatga tatggcaaga taagtgtata gtagatagtt
     6001 atgtaatgca tttagacagc cttaccataa aatcagcgaa tggagttgtc ttctggtggt
     6061 gttcgctatt cccgccagac gatggttggc ttaaaggcga cacttcttgt ggcaaaggct
     6121 acagaagtaa agcggtataa atgcaagttg gttaactctc acagccagat tcccccccga
     6181 tacctaggag gtttttatgt cacagtcaaa tatccagatc atgtcacctt tgtaggttgg
     6241 gttgaggaac gaaacccaac atgctttccc tggagttggg taacgcttac gctctaccca
     6301 acctacgaga atattttgtg caaaacttac atgttcccgg agggttttat gtcacagtca
     6361 aatatccagt catttaacgc tgaagaccta tcagcggagg aattacaact acaaaaagcg
     6421 cagcaagtca tagatgaact gtttatggct gccgaatcgg atgagaagct taatgagcaa
     6481 ctcgaagcgg cgattagccc agaaagcttg gtggaaatcg ctacccgtca agggtacaaa
     6541 ttgacagtag cggatttaga aatgctacat cattatgacc aagagcaagc acaacttaac
     6601 tcggatgagt tggatgatga tgaactcagc gaacaagagc tagagctagt cgctggtggt
     6661 cgtgctaaag gtcttacatc tcttactgcg cctcctaagc cggttccgag tggttttaat
     6721 ccctctccga aatctcaagg gtttcctgtt ccttggtggc cttggtgagc ttaacagtgg
     6781 catagcttga ggaatttacc ccataactag aagatactta tgttacagcc agagatccaa
     6841 gcacttaaag ccgaaaactt atcaactttt aacagtgatg aggatgatga actcagtgaa
     6901 caagagttag agctagtcgc tggtggtaat ggctttaatc caccaacatc agaacctggt
     6961 tgggttcacg atccaacttg ccctaattac agagctggca tggagcaata actaagcagt
     7021 tgcccgatac ctaggaggtn tttatgtcac agttaaatat ccagtcattt aaagcattag
     7081 acgtatcagc ggaggaatta aaactacaaa aagcgcagca agtcatagat gaactgttta
     7141 tggcggctaa ctcgaatcag aggctctttg agcaactcaa agcggcgatt agcccagaga
     7201 acttggtcga aatcgctgtc cgtcaagggt acgaattgac agtagcagac ttagaaaggc
     7261 tacatcatta tgaccaagaa caagcacaac ttaactcgga tgagttggat gatgatgaac
     7321 tcagtgaaca ggagctagag ctagtcgctg gtggatgtgg ctttattcaa ggattatcaa
     7381 aaatttcctt ttggatgaaa aatcgttctg ggaaacagta ctttggcccg atgtcatata
     7441 aacgcggtca gtcatgaaaa ccgatagctt tttggggaaa tgttctcctt tattgtggag
     7501 cagttgttta atccttggtg gagcgctgct aaacacagat actacctcag cacagctcat
     7561 ccccgatgcc actctcggta acgaaagctc agtcgttact cctaatgtca atatcaatgg
     7621 tttaaccagt gaccaaattg atggcggagc aaccagagat gctaacctgt tccacagttt
     7681 tggacaattc aatgtcgggg aaggcagggg agtctatttc tccaatccca cagggattga
     7741 acggattctc acgcgagtca ctgggggaaa tgcttctaat atcctgggaa ccttgggagt
     7801 tttaggcaac gctgacctat ttttaattaa ccccaatgga attatctttg gtgcaggctc
     7861 tcaactcgac ctgagaggtt catttattgg cagtacggcg aatagcatcc aatttgccga
     7921 tggtctagaa tttagtgcta ccaaccccca aaccctaccc ttactaacga ttaaagttcc
     7981 cttgggctta caatatgcag ccaatccggg agggattcaa gtgcaggggt tgggcaacca
     8041 agtcatcatt gatccccaaa cctttgtatt cattggcgta gatggaaaag gtcttgaagt
     8101 agagcagaat caaaccttag ccttagtggg cggtgaggta gccctttctg gcggaaatct
     8161 aaccgcaaaa ggcggaactc tggagttggg aagtgtacag gaggggctag tcacccttac
     8221 cccaaccaat ccgggctggg cattgagcta tcaaggcgtg gaaaatttcc aagatatcct
     8281 gctgtcccaa ggggctatga ttaacaccag tggtccgaca ccgggaagaa ttcaggtaca
     8341 aggacggcgc gtcaccctct ccgacggttc aggactggtg gcaactaacc tgggaattgg
     8401 aaacggcgag aacgtaacta ttactgcctc agagttaatc gagttgagtg ggacaaatcc
     8461 tctcaatggt cttcctagct tcttgttttc tggtacaaca acggctggaa agggcggtgg
     8521 cgtgaccctg accacagagc ggttgcggct gcgggatggg gcgcaagtct catctggtac
     8581 ggctggttcg ggcagtgcgg gtatgctcag cgtgaatgct tcgcagtccg tagaactgat
     8641 tggagtctca atccctgacc tgttttccag tggtttattt agcagcagta gttttgccgc
     8701 cactggagac gcggggaatt taaccattaa caccgagcaa ttcattctcc gggatggggc
     8761 aacagttagc agtgaaacct ctggtgcggg tcgtggggga gatttgacta taaacgcttc
     8821 gcgctctgtg gagctaactg tcacaaaccc aaatggcttt cccaccagtt tatcgacggc
     8881 gactcgaggc agtggaaatg cgggcaactt gacgattaat acaggacgct tgattgtccg
     8941 ggatggcgcc caagccgcca gttcgacaag tagtcaaggt tctgggggaa acctgagtgt
     9001 gaacgccgag gagtcggtag aaataatagg tacgtcagcc aattctgcca gcggcttgtt
     9061 tgcctcggcg attatcggtg atggagccgg gggcgacttg aggattacta ctcctcggtt
     9121 aattgtccgg gatggggcat tgctcagtgt gagtaacttc caaagccgca acctggcacc
     9181 gccgggaacg ggtcctgcgg gcaaccttga gatagaggct gccacaatcc gactggaaaa
     9241 tcaaggggtg atcacagccg ctgctgctgg aggagaccag ggaaatatta ccctggattc
     9301 ccaagacatc cagatgcgcc gacagagtgc catcaccacg aacgccaccg gaccgagcgc
     9361 gggtggtaat atcacgctca acaccgatac cttagtcgcc ctggacaata gcgacatcac
     9421 ggcgaatgcc acgaatagtc aaggtgggcg cgtcatcgtc aatgcacaag gcatcttcgg
     9481 cactcagttc cgtccccaac tcaccataga aagcgacatc accgccagtt cggacttggg
     9541 ggctgaattc agcggcattg tggaaattaa cacccctgat gctgatccga gttctggatt
     9601 agtcgaatta tcaacaactg ttgttgatgt cgaaggctta gtggcacaaa atctctgtac
     9661 agcgaaacaa gcgggtagtt cctttgtcat cagcggacgc gggggtttac ccaccagtcc
     9721 gaatgacccg ttgactgatg aagttgtggt ggtggagtgg tctcaaccga gtactgaggt
     9781 gtcgtctgga ggggtgagtc atccgccatc aaccgatagt ggacaacgga aaaatcgggt
     9841 gattcggcaa atacaaggct ggtttgtcgc ggctgatggg acagttatcc tgactgacgc
     9901 cgcacctact gtgacaccgc agagtcctgc cttgactcac cccggttgtg ttccacctag
     9961 aatgtctctc cagtagagac gcgccatggc ggtagagacg cgccatggcg cgtctctaca
    10021 aaagggggga tttgggggga ttttgttaca gtacacccca cacctaaccc ccacgttttt
    10081 gatgccgtga aaactcagtt caatttttcc caaaacccaa aacccttacg aatgacaaat
    10141 gacaaatgac gaatgacgat ctcaacggtt aactttaatt gtgtccacct acttatcatt
    10201 cttgctttca gcccagtggc ggcacccgtt agcgcccaaa tgggagaatt cgcggatacg
    10261 aggttacaac cagagataca gcactttccg ctcttattgg atacgtttga tccccctaaa
    10321 tcccccatgg aacaaaaagc gaagcatccg ctggtctccc ccatggaaca aaaagcgaag
    10381 catccgctgg tctcccccat ggaacaaaaa gcgaagcatc cg
//
