LOCUS       c00682_3300000..       10948 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300000980.a:BBAY79_10000673.
ACCESSION   c00682_3300000..
VERSION     c00682_3300000..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 05:47:13
            Original ID  :: 3300000980.a:BBAY79_10000673
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10948
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..516
                     /locus_tag="ctg682_1"
                     /transl_table=11
                     /translation="YLASMLWSNAVGGYDQILEQLDLPPEITAEFQTIIDSGMLDTLMG
                     VGGVLSLIFIPLGFLISTGLRHLVAKILKGKGTFGNYAYLNAAIEAPIKIISAIVSFAP
                     GIGTCISLLLSVYMYVQRYHATKVAYQLSSGKAIAVVLIPILLLFALGACGVIAFGILM
                     RAYLEMPF"
     protocluster    1..10948
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[8127:10946]"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      8128..10946
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..10948
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10948
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="(cds(Condensation and (AMP-binding or A-OX)) or
                     (Condensation and AMP-binding))"
                     /tool="antismash"
     CDS             complement(520..1326)
                     /gene_functions="other (smcogs) SMCOG1097:transposase
                     (Score: 186.5; E-value: 8.5e-57)"
                     /gene_kind="other"
                     /locus_tag="ctg682_2"
                     /transl_table=11
                     /translation="MSANNQVYSSDLSNAEWNIISALLPRNTGGPGRPIETCLRSVVNA
                     IMYLNRAGNQWNLLPSNFPPKGTVYYHFRKWALDGTLEKINQALCKMDRVLRDREPVPT
                     GAAIDSQSTKTTEVGGKERGKDTYKRVNGRKRHIIVDTLGNLWAAFVNAASSDDRESIK
                     QAFAKLPQEVRFSIQKIWADGGYRGEPFETWLQQNIQCEIEIAVRPPNAEGFILVPVRW
                     VVERTFAWLGRYRRLSKDYERCTKSSQGMIYLASIRTMLKRIAAHA"
     CDS             1441..1767
                     /locus_tag="ctg682_3"
                     /transl_table=11
                     /translation="MKDDKADWLIFCEAALRVGNFRSFDEIILLALDAWFEQLPSNLRW
                     DIAIELYTNERISTGKAARIAGMNYVVFMEALSERGIPFMAAELPTGEARAKQEALLDA
                     LIAV"
     CDS             1748..2230
                     /locus_tag="ctg682_4"
                     /transl_table=11
                     /translation="MHSSQSEGSEGIVFDTNVLSIFSKGDQTNLLFQTFAYSYETNQLY
                     ISPAIKQELEDGAQRGIAHLIEVLKLIEQGHIQIINPTELDRQFMKNLPPKLDIGEAEA
                     IAICHRLEYIFISHDRKAINYCEREGISYINLSVLFERLKQMQLLTESDIKQMLGP"
     CDS             2227..4017
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 385.3; E-value:
                     8.4e-117)"
                     /gene_functions="resistance (resist) ABC_efflux (Score:
                     319.5; E-value: 2.6e-97)"
                     /gene_kind="transport"
                     /locus_tag="ctg682_5"
                     /transl_table=11
                     /translation="MKPLRFLFIYARNYTGVLLITVVSMLCLVGAQLLIPWIIRSMIAA
                     VTNLEGSTMSLPFVTRLALLALGVYVAKAGFQFLRSYMAHIAGWGVVADARRLIYGHMQ
                     RLSLRFYEDKQTGQLMSRLVNDTDKFELLIAHAIPDIIVNVLTLIGVTGVLLFLNWRLA
                     LFSMLPIPLILFALKIFARYVRPAFLREREKLGNLNAILNDNISGIREIKTFTRERAEM
                     RRVNLHIDEYRDSTLYALKMLAIFRPFIEFTSALGTIVVIYFGGRLILDEVLAIEDLVA
                     FFLYLELFYQPLHHLSDAWEKIQEALASADRVADLMDVTPEVQERENAIALPERVEGSV
                     RFQDVTFGYLPDETVLEEVSFHIQPHSKVALVGPTGVGKTTLVSLIPRFYDVEGGAILI
                     DDHDLRDVTLESLRQQISIVLQDVFLFHGTARENILFGRDNATEAEMIEAAKAANAHEF
                     LSQLPDGYDTLIGERGVKLSGGQKQRLSIARAILKDAPILILDEATSSVDTETEFLIQQ
                     ALERLMVGRTTIIIAHRLSTIRNADMIVVLDDKGVVERGTHPQLMAEEGLYWRLNQIQE
                     QSDLQWCLPTSEDEYVSAAA"
     CDS             4572..5246
                     /locus_tag="ctg682_6"
                     /transl_table=11
                     /translation="MKIIGAGLGRTGTSSLKAALEMLGFGPCYHMQEINKHPEHIPIWL
                     DAVAGKPVDWVTFLQPYQAMLDWPACDHYATLMATYPEAKVLLSVRDPEKWYDSVHETI
                     YTFNKTFPEWAMSVAPKLADQVDMTRTQVWQKKFNNRFEDRAYAIDIFQQHNKRVQQLV
                     PASRLLVYEVSQGWAPLCDFLDVPIPANEPFPHVNDKAQFKRLITWLHSQSKKKAKPEK
                     AT"
     CDS             5340..5972
                     /locus_tag="ctg682_7"
                     /transl_table=11
                     /translation="LLRLEFGQGPQNYLDVASKADEESFIEQARSAAKPHPARDYYRAL
                     KVPMIYQNHMHARDLMALLEPEVWQRSYKFSIERHPYEKAISFAWFFRNIVTHKADGAI
                     NQLENRLGDLSQTIDFVLKRRLIRNYDIYAMDGQVVADKVVRYEYLAADLRAVEKEIGL
                     PILDHLPRTKATSRKDRTPARAILSPQQKEIIQTLCAEEFELFGYEK"
     CDS             5992..7572
                     /locus_tag="ctg682_8"
                     /transl_table=11
                     /translation="MQSTGLQNDATPSESALSHRDSRPLNGEEYLASLHDGREVWIYGE
                     RVADVTAHPAFHNTARILARLYDALHDAEKQPILTCPTDTGSAGYTHRFFRVARSVDDL
                     IASRDAIVEWARMTYGWMGRTPDYKGAFATSLGANPDFYDPYQANAQRWYHEIQEKVLY
                     LNHAIADPPVDRNLETGNIAGIQMSVVRETDAGIVVNGAKTVATNSALTQYTWIGQAGP
                     VKKKEHALNFILPMSTPGVKLLCRPSYQMAAQAVGSPFDYPLSSQYDENDAILICDEVL
                     VPWENIFIYGHLRKTATYLPRSGFATNASFNSCIRLGVKLDFLTGVLFKSLEMTGSLQH
                     RGVQVHVGEVLAYRNLIRSLTEAMMRNPDSWENGTVLPNREAVLAYRALAPNIYSKIKE
                     IFQDVVASSLIYYNSHASDFQNPELRPYLDTYLRGSQGQDAEERVKLAKLAWDALGTEF
                     GSRHELYERNHGGNHEVIRLNNYRHALASGQAKECKALVDACLSEYDLNGWTRDDLASA
                     APANSFINN"
     CDS             7690..7947
                     /locus_tag="ctg682_9"
                     /transl_table=11
                     /translation="MDTRTIILEQLAEIVEEFSPLSFPEAVSDGTALADFWLDSVAFVA
                     LISNLEDALGYIPTAITEGEFDPKTVGDFVTLYTSEPAVA"
     CDS             8128..9201
                     /NRPS_PKS="Domain: Condensation_LCL (53-338). E-value:
                     4.1e-85. Score: 277.1. Matches aSDomain:
                     nrpspksdomains_ctg682_10_Condensation_LCL.1"
                     /NRPS_PKS="type: NRPS-like protein"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     256.9; E-value: 7e-78)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg682_10"
                     /sec_met_domain="Condensation (E-value: 1.1e-58, bitscore:
                     188.1, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNSRQIAITTLPKNRVQQTTSPNGKAGALATAMRLFRNRKETPTI
                     EKADPDIPQPLSYAQELLWLFQQINPESTVYNRVHAFRLQGTLNISALEKAINEIMRRH
                     TILRTTYHLADDQPIQRVLPHRAEQLEVMDLRGSAMETARDRYLPYLQAQMTQPFDISQ
                     EKICRFQLLQMAEEDFILVFCVHHIGYDVSSERVLFRELGILYEAFCLNKPSPLPELAI
                     QYSDYAAWQRQSLNDVLLLEKLDFHQQLLDSELPLLELPSDMPRLNEVDTQGKTHIIPL
                     DPELSQALRRLSQNEGVSFFDTMLTVFYVLLYRYTYQEKVVVGTPVTNRNQADLHKLLT
                     LPSPICSNACKTVQQKP"
     aSDomain        8287..9141
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg682_10_Condensation_LCL.1"
                     /domain_subtype="Condensation_LCL"
                     /evalue="4.10E-85"
                     /label="ctg682_10_Condensation_LCL.1"
                     /locus_tag="ctg682_10"
                     /protein_end="338"
                     /protein_start="53"
                     /score="277.1"
                     /tool="antismash"
                     /translation="QPLSYAQELLWLFQQINPESTVYNRVHAFRLQGTLNISALEKAIN
                     EIMRRHTILRTTYHLADDQPIQRVLPHRAEQLEVMDLRGSAMETARDRYLPYLQAQMTQ
                     PFDISQEKICRFQLLQMAEEDFILVFCVHHIGYDVSSERVLFRELGILYEAFCLNKPSP
                     LPELAIQYSDYAAWQRQSLNDVLLLEKLDFHQQLLDSELPLLELPSDMPRLNEVDTQGK
                     THIIPLDPELSQALRRLSQNEGVSFFDTMLTVFYVLLYRYTYQEKVVVGTPVTNRNQAD
                     LHKLL"
     aSModule        8287..9141
                     /domains="nrpspksdomains_ctg682_10_Condensation_LCL.1"
                     /incomplete
                     /locus_tags="ctg682_10"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       8350..8463
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg682_10_0001"
                     /evalue="1.90E-14"
                     /label="C2_LCL_024-062"
                     /locus_tag="ctg682_10"
                     /protein_end="112"
                     /protein_start="74"
                     /score="46.0"
                     /tool="antismash"
                     /translation="VYNRVHAFRLQGTLNISALEKAINEIMRRHTILRTTYHL"
     CDS_motif       8680..8745
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg682_10_0002"
                     /evalue="1.40E-03"
                     /label="C3_LCL_132-143"
                     /locus_tag="ctg682_10"
                     /protein_end="206"
                     /protein_start="184"
                     /score="11.5"
                     /tool="antismash"
                     /translation="VHHIGYDVSSERVLFRELGILYE"
     CDS_motif       8794..8832
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg682_10_0003"
                     /evalue="6.00E-06"
                     /label="C4_LCL_164-176"
                     /locus_tag="ctg682_10"
                     /protein_end="235"
                     /protein_start="222"
                     /score="18.7"
                     /tool="antismash"
                     /translation="QYSDYAAWQRQSLN"
     CDS_motif       9088..9141
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg682_10_0004"
                     /evalue="4.90E-06"
                     /label="C5_LCL_267-296"
                     /locus_tag="ctg682_10"
                     /protein_end="338"
                     /protein_start="320"
                     /score="19.0"
                     /tool="antismash"
                     /translation="VVVGTPVTNRNQADLHKLL"
     CDS             9174..10946
                     /NRPS_PKS="Domain: AMP-binding (157-580). E-value: 5.3e-98.
                     Score: 320.0. Matches aSDomain:
                     nrpspksdomains_ctg682_11_AMP-binding.1"
                     /NRPS_PKS="type: NRPS-like protein"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     294.8; E-value: 1.6e-89)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg682_11"
                     /sec_met_domain="AMP-binding (E-value: 4.3e-106, bitscore:
                     344.4, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VQNRSAEALTHPDVPFHKLFQHLQAAQDDAPTNTENPNGFQALFN
                     MPGKRNELNLYGLTVERLTFKAIDTQADFSLSVRQGRQGTELHFTYRAQLFSEPRIAQM
                     ATHYEKLLQSVTENPVQPIAQLPMLTDVERHQLLVEWNDTTTDYAKDKCVHLLFEEQVA
                     LAPYAVALVFEGEQLTYQELNKRANQLAHHLIAYGVGSRNSEYCEDISGTGGEKIVALL
                     ARRGPDFLIAMLAIFKAGGIYLPLDPRNPTDRHRQMLEQCRNPLILAADEFIPGLGCLV
                     SSATSSQILSLGSSLIQTYSDKNLAACSRPSDLAYILFTSGSTGLPKGAMIEHQGMLNH
                     LYAKISDLELSATDRIAQTASQSFDISIWQFLAGLLVGSTVHIYGDDTALDPPYLLKQI
                     ELDQISIWETVPSLMQALMGAVDQQPLHPLSALRWLIPTGEALSPQLANQWLSIYPRVP
                     LLNAYGPTECSDDVTHYVIDQPLPSGTTQTPIGHPVINIQAYILDAAMQPTPVGVSGEL
                     WIGGIGVGRGYLNDPDRTAAVFVPNPFSDVPNAKLYKTGDLCRWLPDGNIEFRGRTDFQ
                     VKLRGFRIELGEIES"
     CDS_motif       9183..9263
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg682_11_0001"
                     /evalue="5.70E-04"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="ctg682_11"
                     /protein_end="30"
                     /protein_start="3"
                     /score="12.2"
                     /tool="antismash"
                     /translation="RSAEALTHPDVPFHKLFQHLQAAQDDAP"
     aSDomain        9645..10913
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg682_11_AMP-binding.1"
                     /evalue="5.30E-98"
                     /label="ctg682_11_AMP-binding.1"
                     /locus_tag="ctg682_11"
                     /protein_end="580"
                     /protein_start="157"
                     /score="320.0"
                     /specificity="consensus: X"
                     /tool="antismash"
                     /translation="FEEQVALAPYAVALVFEGEQLTYQELNKRANQLAHHLIAYGVGSR
                     NSEYCEDISGTGGEKIVALLARRGPDFLIAMLAIFKAGGIYLPLDPRNPTDRHRQMLEQ
                     CRNPLILAADEFIPGLGCLVSSATSSQILSLGSSLIQTYSDKNLAACSRPSDLAYILFT
                     SGSTGLPKGAMIEHQGMLNHLYAKISDLELSATDRIAQTASQSFDISIWQFLAGLLVGS
                     TVHIYGDDTALDPPYLLKQIELDQISIWETVPSLMQALMGAVDQQPLHPLSALRWLIPT
                     GEALSPQLANQWLSIYPRVPLLNAYGPTECSDDVTHYVIDQPLPSGTTQTPIGHPVINI
                     QAYILDAAMQPTPVGVSGELWIGGIGVGRGYLNDPDRTAAVFVPNPFSDVPNAKLYKTG
                     DLCRWLPDGNIEFRGRTDFQVKLRG"
     aSModule        9645..10913
                     /domains="nrpspksdomains_ctg682_11_AMP-binding.1"
                     /incomplete
                     /locus_tags="ctg682_11"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       9873..9914
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg682_11_0002"
                     /evalue="4.20E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg682_11"
                     /protein_end="247"
                     /protein_start="233"
                     /score="16.7"
                     /tool="antismash"
                     /translation="LAIFKAGGIYLPLDP"
     CDS_motif       10116..10175
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg682_11_0003"
                     /evalue="1.20E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg682_11"
                     /protein_end="334"
                     /protein_start="314"
                     /score="30.1"
                     /tool="antismash"
                     /translation="AYILFTSGSTGLPKGAMIEHQ"
     CDS_motif       10701..10790
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg682_11_0004"
                     /evalue="1.20E-16"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg682_11"
                     /protein_end="539"
                     /protein_start="509"
                     /score="52.7"
                     /tool="antismash"
                     /translation="PVGVSGELWIGGIGVGRGYLNDPDRTAAVFV"
     CDS_motif       10878..10943
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg682_11_0005"
                     /evalue="1.90E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg682_11"
                     /protein_end="590"
                     /protein_start="568"
                     /score="35.9"
                     /tool="antismash"
                     /translation="FRGRTDFQVKLRGFRIELGEIES"
ORIGIN
        1 tatctcgcca gcatgctttg gtcgaacgct gtgggcggct atgatcagat attggagcag
       61 cttgatttgc cgccagagat cacggctgaa tttcagacta ttatagatag cggaatgttg
      121 gataccctca tgggtgtagg aggggtgcta tcgctcattt tcattccgtt gggttttctg
      181 atctccaccg gtctccgtca tttggtggcg aaaattctca aaggaaaagg tacgtttggc
      241 aactatgctt atctcaatgc tgccatcgaa gcaccgatta aaattatcag tgccatagtc
      301 agttttgccc ctggcatcgg tacctgcatc agcctgttgt tgagtgtcta tatgtacgtt
      361 cagcgttacc atgcaactaa agtggcctat caactctcct ctggcaaggc gattgccgtg
      421 gtgttgatac cgattttgtt gctctttgca ctcggcgcgt gtggtgtgat tgcatttggt
      481 attttaatga gagcgtattt ggaaatgcct ttttaaggtt caagcatgag ccgcaattct
      541 cttgagcata gtgcgtatag aagcaagata aatcatgcct tggctgctct tagtgcatcg
      601 ttcataatcc ttgctaagcc gtcgatatcg tccaagccat gcaaatgtgc gctcaacgac
      661 ccatcgaacc gggacgagaa taaagccctc ggcattagga ggccgaacag cgatttcgat
      721 ttcacactga atattttgtt gaagccatgt ctcaaaaggt tcgcctcggt atccgccatc
      781 ggcccaaatt ttttgaatag aaaatcgtac ttcttggggc agtttagcga atgcttgttt
      841 gatactctct cggtcatccg aactagcagc attaacaaat gcagcccata gattgcctag
      901 ggtatcaaca atgatatgtc gttttcgtcc attcactctt ttgtaggtat ctttccctcg
      961 ctcttttcct cctacctcgg tggttttcgt tgattggctg tcgatggcag cccctgtagg
     1021 tacaggttct cggtcccgaa gcactcggtc catcttacat aaggcttgat tgattttttc
     1081 gagggtgcca tcgagtgccc atttacgaaa atggtagtag actgttcctt ttggtggaaa
     1141 atttgatggt aagaggttcc attgatttcc tgcacgattt aggtacataa ttgcattgac
     1201 caccgaacgc aggcaagttt ctatggggcg tcccggacca cctgtattcc gtggtagcaa
     1261 agcagatatg atattccatt ctgcattgct taggtcactt gaatacactt gattgttagc
     1321 tgacatagtt tggcttcctt tcttgtcaca atatttattt caatcgagaa atattgtggt
     1381 tctataggcg ttctgtgtca agaaaaatag tccatgatta tccgacaaac agatagacct
     1441 atgaaagatg ataaagctga ttggctaatt ttttgtgaag ctgcattgcg cgttggtaat
     1501 ttcagatcat ttgatgagat tattctgctt gctttagacg cttggttcga gcaactgcca
     1561 tcgaatctac gctgggatat tgcgattgag ctttatacaa atgagcgaat cagcacaggc
     1621 aaagcagcca gaatagcagg catgaattat gttgtcttta tggaggcttt gagcgagcga
     1681 ggcattccgt tcatggcagc agaactacca accggagagg caagagcaaa gcaggaggcg
     1741 ttattagatg cactcatcgc agtctgaagg ttctgaaggt attgtatttg atacaaacgt
     1801 gctttcaatt ttttctaaag gcgatcaaac gaatttacta tttcaaacgt ttgcctactc
     1861 ctatgagaca aatcaactat atatttcacc tgcgatcaaa caggaattag aagatggtgc
     1921 tcaaagagga attgctcatt tgatagaggt tttaaaactg attgaacaag gccatattca
     1981 aataattaat ccaactgagt tggatcgaca atttatgaag aatctgcctc ccaaattaga
     2041 tattggtgaa gctgaagcaa tagccatctg tcacaggcta gagtatatat tcatctctca
     2101 tgatcgtaag gccattaatt attgtgaacg agaggggata tcttatatta atctatctgt
     2161 cctatttgaa agactgaaac aaatgcaatt actgacagaa tctgatataa agcagatgtt
     2221 gggaccatga aaccactacg cttcctgttt atctacgctc gtaactacac cggcgtcctc
     2281 ctcatcaccg ttgtcagcat gttgtgcttg gtcggcgcac agctcctgat cccctggatc
     2341 atccgctcca tgattgcagc tgtgaccaac ctagagggca gcaccatgag cctgcccttt
     2401 gtgacccgcc ttgctctatt agcgctgggg gtctatgttg ccaaagctgg ctttcaattt
     2461 ctgcgaagct atatggccca catcgcaggc tggggcgtgg tcgccgatgc ccgccgcctg
     2521 atctatgggc atatgcagcg gctctcactt cgcttctatg aagataaaca gaccggccaa
     2581 ctcatgtctc ggttggtcaa tgacaccgat aaatttgagc tgctcatcgc ccatgccatc
     2641 ccggacatca tcgtcaacgt tttgactctg atcggtgtaa caggtgtgct actcttcctc
     2701 aactggcgac tggctctctt cagcatgttg cccatcccat tgattctctt tgcactcaaa
     2761 atctttgcca gatatgtccg tccagccttc ttgcgcgagc gggaaaagtt gggtaacctc
     2821 aacgcgattc tcaacgacaa catttctgga atccgtgaga tcaagacctt cacccgcgaa
     2881 cgggccgaga tgcggcgggt taatcttcac attgatgaat atcgcgattc caccctctat
     2941 gcgctcaaga tgctggctat ctttcgcccc tttatcgagt ttacctcggc gctgggtacc
     3001 atcgtcgtga tctattttgg cggtcggctc atcttagatg aggtgttagc gattgaagat
     3061 ttggtggcct tcttcctcta tctggagctt ttctaccagc cattacacca tctcagcgat
     3121 gcctgggaga agattcaaga agccctagct agcgcggatc gagtggctga tctcatggat
     3181 gtaacgcctg aagtgcaaga acgagagaac gccattgcct tgccagagcg ggtagaaggc
     3241 tcagtccgct tccaggatgt gaccttcggt tatctacccg atgaaacagt cttagaagag
     3301 gtctccttcc atatccaacc ccatagcaaa gtggcgctgg tgggtccaac cggcgtaggt
     3361 aagaccacgt tggtgagcct catcccccgt ttttatgatg tggagggcgg ggccattctc
     3421 attgatgatc atgacttgcg ggatgtgacg ctggagagct tacgccagca gattagtatc
     3481 gtgttgcagg atgtctttct ctttcatggc acagcccgtg agaacattct ctttgggcgc
     3541 gataacgcga ctgaggcaga aatgatcgag gcggcaaagg cggccaacgc acatgaattt
     3601 ctcagccaat tacccgatgg ctatgatacg ctcattgggg agcgcggggt gaagctctct
     3661 ggtggtcaga aacagcggct ttctattgcc agagcgatcc tcaaggacgc acctattttg
     3721 attttagatg aagcaacttc gtcagtggat acagagacag aatttttgat tcaacaggcg
     3781 ttagaacggc ttatggtggg ccgtactacc attattattg cccatcggct ttccaccatt
     3841 cgtaatgctg atatgattgt tgtgctggat gataagggtg tcgtagagcg aggtacccat
     3901 cctcagttga tggcagagga agggctatat tggcggttga accagattca ggagcagagt
     3961 gatctgcagt ggtgcttgcc tacgagcgag gatgaatatg tttctgctgc ggcgtaatgt
     4021 aaaaaatttt tgctcagagt cagtttgaac attatagcca tatgcagtta taagagcgtg
     4081 tctacttcgc aataggggct gagaattgca ctgaagattt gtaaccattc agtttccacg
     4141 tgtagctagc acgccctcgt gcggctccct tctaagcagg actggcacga ggcatgccta
     4201 ctgaacagga ggaaggtgag cgattacaaa aatctattgc atttctgacc ttactcttta
     4261 atatctttaa taattcgttt tttttctttt ttcgtaatcc aatggcacag gcatacgtgg
     4321 cggatatggt atgatcaaat tagaggtatg ccacgtttgt gccacgtttt tatgctaaac
     4381 tgcaatgtag cccccacgaa taagtgtaac ctatagtgcg actttactct ggatagaatt
     4441 ggcacgaggt gtgcctacta aacagggaac tgaatgatta caaagaggtt atgtagatta
     4501 cagaagcagc ttgcagaaat gctgaacgac ggaagaaatt ttacaaatcc gtaatagaaa
     4561 gagtctttta tatgaaaatc atcggtgccg ggctaggacg gactggaacc tcctcgctta
     4621 aggcagcact tgaaatgctc ggttttggtc cctgctatca catgcaggag atcaacaaac
     4681 atcctgaaca tattccgatc tggctggatg cggttgctgg aaaacccgtg gattgggtga
     4741 cttttttgca gccctatcaa gccatgctgg actggcctgc ttgtgatcat tatgccacct
     4801 tgatggcgac atacccagag gccaaggtac tcctgagtgt gcgcgatcca gagaaatggt
     4861 atgacagtgt ccatgagact atctacacgt tcaacaaaac ctttccagag tgggcaatgt
     4921 ctgttgcccc gaaactggcg gaccaagtgg atatgacacg gacacaggtg tggcagaaaa
     4981 aattcaacaa tcgttttgaa gatcgcgcgt atgccatcga catttttcaa cagcacaata
     5041 aaagggtcca acaacttgtt cctgcaagcc gcctcttggt ctatgaggta agccagggct
     5101 gggcaccttt atgtgacttt ttggatgtgc ctatacctgc caacgagcct ttcccacatg
     5161 tgaatgacaa agcgcagttt aagcggctga tcacttggct gcattcacaa tctaagaaaa
     5221 aagccaaacc agagaaagca acatgattat ctcttttgcc cacaacttta tctttatgaa
     5281 cgctaagtca ttcgctagaa gccgatgaca ttgctacgcc cattagccca gaagatgaat
     5341 tgctacggct tgaatttgga caaggccccc aaaattatct cgacgtagca tccaaagcgg
     5401 atgaagaatc atttattgag caggcgcgtt cggctgccaa accccatcct gcccgcgact
     5461 attatcgagc gttaaaagtt cccatgattt atcagaacca catgcacgca cgggatctca
     5521 tggcgttgct cgagcctgag gtttggcaac ggagctataa gttttcgatt gagcgccatc
     5581 cctatgaaaa agcgatctcc tttgcctggt ttttcagaaa tattgtgacc cacaaggcag
     5641 acggggcaat caatcagtta gagaaccgac tcggcgacct ctcacaaacc attgactttg
     5701 tgctcaaacg ccgcttaatt cgcaattatg atatttatgc catggatggg caagtggtcg
     5761 ccgacaaagt ggtgcgctat gaatacttag ccgcagattt acgggcggtc gaaaaggaga
     5821 tcggtctacc gatactcgat catttgccac gcaccaaggc gacttcgcgc aaagacagaa
     5881 ccccagccag agcgatctta tcaccacaac aaaaagaaat cattcagaca ttatgtgccg
     5941 aagagtttga gctgtttggc tatgaaaagt aaatgaggag tattatctta tatgcagagt
     6001 acaggcttac agaacgatgc aacgccttct gaatcagctc tatctcaccg tgatagtcgc
     6061 ccgctgaacg gcgaagaata tctggcttcc ttgcacgatg gacgtgaagt ttggatctat
     6121 ggtgaacgag tcgccgatgt cacagcacac cctgcttttc acaacacggc ccgcattctg
     6181 gcacggctct atgatgccct ccatgatgcc gaaaaacaac ccatattgac ctgcccaact
     6241 gacaccggtt cggcgggtta tacgcatcgt ttttttcgcg ttgcgcgcag cgtggatgat
     6301 ctaatcgcct cccgagatgc tattgtggaa tgggcacgta tgacctatgg ttggatgggg
     6361 cgcacacccg attacaaagg cgcgtttgcc acatctttgg gcgcaaatcc agacttctat
     6421 gacccctacc aagccaacgc ccaacgttgg taccatgaga tacaagagaa ggtcctctat
     6481 ctcaaccatg ccattgccga cccacctgtg gatcggaacc tagaaacggg caatattgca
     6541 ggtatccaga tgagtgtggt ccgtgagacc gatgcgggca ttgttgtcaa cggggccaag
     6601 accgtggcta ccaattctgc actcacccaa tatacctgga ttggtcaagc agggccggtc
     6661 aagaaaaagg aacatgcact caactttatt ctgcccatgt ccaccccagg ggtcaaacta
     6721 ctctgtcgcc cttcctatca gatggctgca caggcggttg gaagtccttt tgattacccg
     6781 ttgagcagcc aatatgatga gaatgatgcc attctgatct gtgatgaagt tctggtgccg
     6841 tgggagaata tttttatcta cggccatcta cgcaaaacag ctacctatct acctcgctct
     6901 ggctttgcca ccaatgcctc gtttaatagc tgtatccgtt tgggggttaa gctcgatttc
     6961 ctaacaggcg tgctcttcaa atctttagag atgactggct cgttgcagca tcgcggggta
     7021 caggtgcatg tgggtgaggt actggcctat cgcaacctga tccggtcgct gaccgaagcc
     7081 atgatgcgta acccagactc gtgggagaat ggtacggtct tgcccaaccg tgaggcggtc
     7141 ttggcctatc gtgcccttgc ccccaatatc tacagcaaga tcaaagagat ttttcaagat
     7201 gtggtggcca gcagcctcat ctactacaac tcccatgcca gcgattttca gaaccccgag
     7261 ctgcgtccct atctggatac ctatctgcgc ggctcccaag ggcaggatgc cgaagaacgg
     7321 gtcaagctgg ccaagctggc ctgggatgcg ctggggacgg agtttggcag ccgccatgaa
     7381 ctctatgagc gcaaccacgg tggcaatcat gaggtgattc ggctcaacaa ctaccgtcat
     7441 gcgctggcct ctgggcaggc caaggaatgt aaggcgttgg tagacgcttg tttgagcgaa
     7501 tatgacctca atggctggac cagagacgac ctggcttctg ccgctcctgc caattcattt
     7561 atcaataatt aggccattcc aaaaccagta tggcggcaag ccactcaaga aaaaacactc
     7621 aaacctggat aattaatcat ctggattagc cttatacaaa cgatcataat atatagaagg
     7681 aatcatacaa tggatacaag aactattatc ttggagcaac tagccgaaat tgttgaagaa
     7741 ttttcgccgc tctcctttcc tgaagctgtc tcagatggga cagccctggc cgacttctgg
     7801 ctagattcag tagcctttgt agctctcatt agcaatttgg aagatgcgtt ggggtatatc
     7861 cccacagcca ttacagaggg cgaattcgat cccaaaactg tgggggattt tgtgacactc
     7921 tatacttctg agccagccgt tgcataagta caaaactgtg acgaaagtga aaattcagga
     7981 ttatggtaca gttcacacat cctcgtgcga tttttctttt ggcaaaatcg gcacgggggt
     8041 gtgcctactt cacgactgat aaaagacgct gcacgattac gggcgaaaac agccgatgta
     8101 aagtcatcgt ttcaaaggga aatcgtaatg aattcgagac agatagcgat tactacatta
     8161 cccaaaaacc gggtgcaaca gacaacatct cccaatggca aagcgggcgc tttggcaact
     8221 gccatgcgtc tcttccgcaa tcgtaaagag accccgacca tagaaaaggc tgaccctgat
     8281 atccctcaac ctctctccta tgcccaggaa ctgctctggc tctttcagca gatcaatcca
     8341 gaaagcactg tctacaaccg cgtccatgct tttcggctcc agggcacgct caacatttct
     8401 gcgttagaaa aagccatcaa tgagattatg cgtcgtcata cgattttacg cacaacttat
     8461 catttggcgg acgaccagcc tatacagcgc gtcttacccc accgcgcgga acagctggag
     8521 gtaatggatc tgcgcggctc tgccatggaa acagcgcgcg accgctatct gccttatctt
     8581 caggcccaga tgacccagcc ctttgacatc agtcaggaaa agatctgccg ctttcagttg
     8641 ttacagatgg cagaggagga ttttatcctg gtcttctgtg tgcatcacat cggctatgat
     8701 gtttcctctg aacgagtcct ctttcgagaa ctgggcatcc tctatgaggc tttttgtttg
     8761 aataaacctt caccactacc tgaactagcc attcaatata gcgactatgc agcttggcaa
     8821 cggcaaagcc taaacgatgt actacttctc gaaaagctcg attttcacca gcaactgctc
     8881 gatagtgaat tacctctcct agagttaccg agtgatatgc cccgtctgaa cgaggtagac
     8941 acgcaaggaa agacacatat catcccgctt gacccagagt tgagccaagc cctgcgtcgc
     9001 ttgagccaaa acgaaggtgt ctcctttttt gacaccatgc tcacggtctt ttatgtgctg
     9061 ctctatcgct atacctatca agaaaaagtg gtggtaggca ccccagtcac caaccgcaat
     9121 caggccgatt tgcacaagct gctgacccta ccttctccga tctgctccaa cgcgtgcaaa
     9181 accgttcagc agaagcctta acccatcctg atgtaccgtt tcataagctc tttcagcatc
     9241 tgcaagctgc ccaggatgat gcgccaacaa acaccgagaa ccccaatggt tttcaggcgc
     9301 tcttcaacat gccgggcaaa cgcaacgagc taaacctgta tggtcttaca gtagagcggc
     9361 ttaccttcaa agcgattgat acccaggccg atttttcgtt aagcgtgcgt caggggcgtc
     9421 aaggtaccga actccatttc acctatcgtg cccagctttt tagcgagccg cgtattgcac
     9481 agatggcaac ccactatgag aaactccttc aaagcgtgac ggagaatcca gtccaaccga
     9541 ttgcccaatt gcccatgctg acagatgtag aacggcatca actgctggtg gaatggaacg
     9601 acacaaccac tgattatgct aaggacaaat gcgttcacct gttgtttgag gaacaagtgg
     9661 cactcgctcc ttatgcggtt gcgcttgtct ttgagggcga acaactaact tatcaggagc
     9721 tgaataagcg tgccaaccaa cttgcgcatc atttaatagc gtacggcgtg ggtagccgta
     9781 attcggaata ttgtgaagat atatctggga cgggtggaga aaaaattgta gcgcttcttg
     9841 cacggcgtgg cccagatttc ttgatagcca tgttagctat cttcaaagca ggtggtatct
     9901 atttacctct cgatccccgc aaccctacag atcgtcatcg tcagatgttg gaacaatgcc
     9961 gtaatccatt gattttagct gccgacgaat ttatacctgg attaggatgt cttgtatcat
    10021 ctgctacctc ttctcagatt ctttcattag gctcctccct aattcagaca tattccgata
    10081 aaaatttagc tgcttgttcc cggccaagcg atctggccta tattctcttt acatctggtt
    10141 ctacaggact gcccaaaggt gctatgattg agcaccaagg catgttgaac catctctacg
    10201 ccaaaataag tgatttggaa ctatccgcaa ctgacagaat tgcacaaaca gcttcacaat
    10261 cctttgatat ctcgatttgg cagtttttgg caggattgct cgttggtagc acagttcata
    10321 tttatggtga tgatactgcg cttgacccgc catacttgct aaaacagatt gaattagatc
    10381 aaatctccat ttgggagaca gtgccttctc ttatgcaggc attaatgggg gcggtcgatc
    10441 aacagcctct ccacccctta tctgcgttac gctggctcat tccaacaggt gaagcattgt
    10501 ctcctcagct tgccaatcaa tggctgtcta tctaccctag agtaccgttg ctaaatgcct
    10561 atggccctac cgaatgctct gatgatgtga cccattacgt cattgaccaa ccgctaccat
    10621 cgggtactac ccaaacgcct attggtcatc cggttatcaa tatacaagca tatatactgg
    10681 atgcggcaat gcaaccgacg ccagttggcg tttcgggcga actctggatt ggaggcatcg
    10741 gtgtgggtcg aggctatctt aatgatccgg atcgtaccgc agcagtattt gtccctaacc
    10801 cattttcgga tgtaccgaat gcgaaactct ataaaacagg tgatttatgt cgctggcttc
    10861 cagatgggaa tattgaattc cgaggccgca ctgatttcca agtaaagcta cggggtttcc
    10921 gtattgagtt aggtgagatt gaaagtat
//
