LOCUS       c00338_3300002..       12173 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300002858.a:JGI1201J43222_100323.
ACCESSION   c00338_3300002..
VERSION     c00338_3300002..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 04:47:05
            Original ID  :: 3300002858.a:JGI1201J43222_100323
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12173
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12173
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[10293:12171](-)"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10294..12171)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
     cand_cluster    1..12173
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /kind="single"
                     /product="NRPS-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12173
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS-like"
                     /region_number="1"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX))"
                     /tool="antismash"
     CDS             454..1938
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 96.3; E-value:
                     4e-29)"
                     /gene_kind="transport"
                     /locus_tag="ctg338_1"
                     /transl_table=11
                     /translation="MTYLRLEGITKRFGSFTANDNISFSVEQGKIHAILGENGAGKSTL
                     MNIISGLYQADKGQIYIQEKPVKIKSSSNAIKLGIGMIHQHFMLIPQLTVTENIILGTK
                     INWRLNIFQRQQEVADLSRAYNLDINPGAKVGDLPIGVQQKVEILKVLYRQAKLLILDE
                     PTAVLTPSEVNSFITILRRLADNGKTIIFISHKLEEVINLCDTVTVLRRGKVITNTTTT
                     DVSPQHLADLMVGHKVALNLDKPQTFPGEIVLSAKNLYIKDDRGINTVCDISFELRAGE
                     IIGIAGVDGNGQRELADGICRLRTIEKGKLEFEQNCTILAYIPEDRQKMGLVLEFNISQ
                     NLILKAFSKIPFCRRFLLQQQAIRDHAISAFDAYDIRAQNSEVKVKQLSGGNQQKIVLA
                     RELNQKPTLIVAMQPTRGLDINATQAVQQKLLAEKERGAAILYISTELEEIMAMSDKIA
                     VMYEGHFSKLLDSATAQVEEISFLMAGGKKWEKNSK"
     CDS             2581..4767
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1216:exopolysaccharide biosynthesis domain protein
                     (Score: 349.4; E-value: 5.7e-106)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg338_2"
                     /transl_table=11
                     /translation="MLKAEKYPQQFLNVNAAQSNDADEGGLNLGRVGAALRRRVLLIAG
                     MTCLVATAAVLKAEIDPRSYQAEIEILTESLSAEAQAVADVPQTLVSQKGLTSVAKGKN
                     VKTTIKVLKSRRVLGPVVRQLQVKYPEIDYEYIASSLKIESTEKHIITVQFIDLREEVV
                     TDVLNAIKDTYLNYSLEERRNDVQEAIKFVEQQKKPLEKRVREWQDKLRRIRQTNNMVD
                     PTQKAQEVSAHITSLNQQLLQNRVQLEQMFAKYQGLQRELAQQPGSLASNPILSENPNY
                     QNILVQIFQVNAEIAKRSSVYTDVDEGMQRLRDQKANMVALLEQERQRVNRDFQSRIQE
                     LRSRDASLVQKINYLNTYMRGLAAVSRDYDNIQRELQIATQALNQFTEKQQALQIEHAQ
                     RLQPWKILDPELTEVNSPKAFSASTKINLILGSMLGMLLGVGSALVVDKLSNVFYTSKD
                     LKEAVKLPLLGVVPLRRELATLSSSQNQNLIPGIQPAARASFFEVFRSLYTNILLLGSD
                     TPIRSLVISSASQEEGKSTVAIHLALSAAAMGQRVLLVDANLRNPTLHKHLGLMNIQGL
                     TDVISSELEWSNIIERSPAEENLYMMSAGPVPPDSIRLLASEKMQDLMNDLQASFDLVI
                     YDTPPLVGFADANLLAANTNGMVLVAALGKLKRTVFQEALEELQISGTPILGVVANRSK
                     DTVHGSYSYYQQYYRQTMKAERIRDSQEAGTTVS"
     CDS             complement(4923..5399)
                     /locus_tag="ctg338_3"
                     /transl_table=11
                     /translation="MVQYTLAQSPEVILTVPGKDSNKAREKAMDKLMEMMDSGELPTNL
                     EDGFSPQQLIEVKESALDNTSKEDKITEAVQILSNLATLKLKVQDSRSEALEVRKAIDI
                     LFTDESVTQEEIAHLKEGFKVLKTFAQANMRYQQAKAKAQDARQVLDDALKSSD"
     CDS             5727..6503
                     /NRPS_PKS="Domain: PKS_KR (2-168). E-value: 7.4e-14. Score:
                     43.8. Matches aSDomain: nrpspksdomains_ctg338_4_PKS_KR.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     182.7; E-value: 1.4e-55)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg338_4"
                     /sec_met_domain="adh_short (E-value: 8.5e-36, bitscore:
                     113.0, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 6.8e-10,
                     bitscore: 27.9, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPTTLITGASGGIGEAFARELAANKNELVIVARSEDKLNQLASQL
                     QEQHKIRVEVIVKDLTAQSATQEVFETVQSKGIAVDTLINNAGFGDYGEFAQTDGERQI
                     KMVQLNIIALMDLTHKFLPQMQQRRSGNIINVSSIAGFQPIPYLSVYAATKAFVLSFSE
                     SLWAENRQYGVRVLVVCPGPTETNFFEEANFPSSFTGKTSKVSTPEEVVRSTLKALEED
                     KSTVVSAGTLGKIIVNMPRFLPRETLVNILEKQFKA"
     aSDomain        5733..6230
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg338_4_PKS_KR.1"
                     /evalue="7.40E-14"
                     /label="ctg338_4_PKS_KR.1"
                     /locus_tag="ctg338_4"
                     /protein_end="168"
                     /protein_start="2"
                     /score="43.8"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="TTLITGASGGIGEAFARELAANKNELVIVARSEDKLNQLASQLQE
                     QHKIRVEVIVKDLTAQSATQEVFETVQSKGIAVDTLINNAGFGDYGEFAQTDGERQIKM
                     VQLNIIALMDLTHKFLPQMQQRRSGNIINVSSIAGFQPIPYLSVYAATKAFVLSFSESL
                     WAEN"
     aSModule        5733..6230
                     /domains="nrpspksdomains_ctg338_4_PKS_KR.1"
                     /incomplete
                     /locus_tags="ctg338_4"
                     /tool="antismash"
                     /type="unknown"
     CDS_motif       5739..5828
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg338_4_0001"
                     /evalue="3.40E-07"
                     /label="PKSI-KR_m1"
                     /locus_tag="ctg338_4"
                     /protein_end="34"
                     /protein_start="4"
                     /score="22.9"
                     /tool="antismash"
                     /translation="LITGASGGIGEAFARELAANKNELVIVARSE"
     CDS             complement(6648..7427)
                     /locus_tag="ctg338_5"
                     /transl_table=11
                     /translation="MLPREELLKGVENRETIAHVIDRAEQAIKTWEVVLTDFLSPPELA
                     EIREIFQRLTDVELIIWGGYPQAERCRIAIARSDLPLDQSQVEIAVLDIAGNFLFDTAT
                     HRDFLGSMLGTGIVREKTGDIIVLGERGAQAIVVPEMVEFLEMNLTQVRSVPVKTQRID
                     LSELKIRQPKKKEMTTVEASLRLDAVASAGFGMSRSKMVDLISGGDVRVNWKEISQASS
                     PIKSGDLIAIRGKGRLEIGDIAVTKKQRYRVQMTKYV"
     CDS             8112..8243
                     /locus_tag="ctg338_6"
                     /transl_table=11
                     /translation="MTDFQILKFTSLTLESATEGLTVQNSITDLLIVSYRSQQIKQQ"
     CDS             complement(8191..8397)
                     /locus_tag="ctg338_7"
                     /transl_table=11
                     /translation="MLLAFFAWYHRLAIGGIARVGQLQLLQPFMTILFSAVLLGEKITA
                     TTITTAIIVVLFVANGRKQSISL"
     CDS             8594..9301
                     /locus_tag="ctg338_8"
                     /transl_table=11
                     /translation="MANSNNPNDIIKRILNGIQTDDDVEALRQLLLAGDRAATPEEYRQ
                     VLQQLSKYNVNITEAKEIHIGDRNYYSWNEEALSALVHMIRFHQSDDVDTANLLVTKLN
                     NARLQGEEGDRKTGSFYTYNVWLEDVCLEKSNDSTENNCCTQQYTIKGKWDSKVYKEVN
                     MFGLRVDKPWGLKKKPHGNFTVTVEILNGRATQVKVDVVRYDDSANNYAADKAKQLINS
                     KIRVVLQKLEMMR"
     CDS             9803..10267
                     /locus_tag="ctg338_9"
                     /transl_table=11
                     /translation="MGRATPLEVILRRDRLVIMVGILGLVALSWAYIVYLALTMENTMA
                     SMGTEVFMSQTSPWGTIEFVLMFVMWTVMMVAMMLLTAVPMILVFATVSRRRQEQRRPF
                     VATSMFLVGYVVIWSGFSLLATLANWELHLPIDVPELVYFIYLQSAVTVF"
     CDS             complement(10294..12171)
                     /NRPS_PKS="Domain: PCP (156-223). E-value: 1.2e-28. Score:
                     90.9. Matches aSDomain: nrpspksdomains_ctg338_10_PCP.1"
                     /NRPS_PKS="Domain: TD (262-502). E-value: 2.9e-89. Score:
                     290.2. Matches aSDomain: nrpspksdomains_ctg338_10_TD.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: NAD_binding_4"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010:NAD-dependent epimerase/dehydratase (Score: 67.4;
                     E-value: 2.3e-20)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg338_10"
                     /sec_met_domain="AMP-binding (E-value: 6.2e-30, bitscore:
                     93.4, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 2.6e-19, bitscore:
                     59.0, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_binding_4 (E-value: 2.9e-78, bitscore:
                     251.8, seeds: 102, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 6.5e-11,
                     bitscore: 31.2, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="NRPQLTSEKFIQNPFSNSKSKRLYKTGDLARYLPDGNIEFMGRID
                     NQVKIRGFRIELGEIEAVLATHPQVNQAVVTAPFISGSKHLVAYVVTQESLCNQQIREF
                     IKSKLPDYMVPSVFIILDSLPLTPNGKVDRKALPEPDFTLQKQEYVAPRTSSEKIIANI
                     FADVLGVENVGIQDNFFELGGHSLLATQLTSRLQQTFQIDLPVSCLFEEPTVAGLAGTI
                     DTILQKGTYTKVTLDLSAEAILDPTIQPQAPIHYVLEPKNIFLTGATGFLGTYLLYELL
                     ERTSANIYCLVRSANAESAKQKLQNKLESHFLWNEKFSSRIIPIVGDLSAQLLGLPTQQ
                     FNQLANQIDVIYHNGAWVNHVYNYLTLKRANVLGTQEVLRLASKHRTKPVHFISTIGVF
                     FTEAYSEIELIQESDIPENSQGLGNGYVESKWVAEKLVMQACERGLPASIYRPAMITGH
                     SQTGVSNTNDFFSRIIKGCIQLGMVPNINSLENLIPVDFVSQAICEISLQKESLGKAFH
                     LINPNSTPTKNLFQWISSLGYPLEEVSLSKWINELIAHPENAMHAYSFNFKSQLQQQKE
                     LSQNYQKIDCQNTLTSLANTDVSIPTVDIKLLETYFAYFVSDGFLNSVA"
     aSDomain        complement(10666..11385)
                     /aSDomain="TD"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg338_10_TD.1"
                     /evalue="2.90E-89"
                     /label="ctg338_10_TD.1"
                     /locus_tag="ctg338_10"
                     /protein_end="502"
                     /protein_start="262"
                     /score="290.2"
                     /tool="antismash"
                     /translation="IFLTGATGFLGTYLLYELLERTSANIYCLVRSANAESAKQKLQNK
                     LESHFLWNEKFSSRIIPIVGDLSAQLLGLPTQQFNQLANQIDVIYHNGAWVNHVYNYLT
                     LKRANVLGTQEVLRLASKHRTKPVHFISTIGVFFTEAYSEIELIQESDIPENSQGLGNG
                     YVESKWVAEKLVMQACERGLPASIYRPAMITGHSQTGVSNTNDFFSRIIKGCIQLGMVP
                     NINSLENLIPVDFVSQAIC"
     aSModule        10666..11703
                     /domains="nrpspksdomains_ctg338_10_PCP.1"
                     /domains="nrpspksdomains_ctg338_10_TD.1"
                     /final_module
                     /incomplete
                     /locus_tags="ctg338_10"
                     /tool="antismash"
                     /type="unknown"
     aSDomain        complement(11503..11703)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg338_10_PCP.1"
                     /evalue="1.20E-28"
                     /label="ctg338_10_PCP.1"
                     /locus_tag="ctg338_10"
                     /protein_end="223"
                     /protein_start="156"
                     /score="90.9"
                     /tool="antismash"
                     /translation="EKIIANIFADVLGVENVGIQDNFFELGGHSLLATQLTSRLQQTFQ
                     IDLPVSCLFEEPTVAGLAGTIDT"
     CDS_motif       complement(11989..12054)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg338_10_0001"
                     /evalue="5.60E-13"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg338_10"
                     /protein_end="61"
                     /protein_start="39"
                     /score="40.6"
                     /tool="antismash"
                     /translation="FMGRIDNQVKIRGFRIELGEIEA"
ORIGIN
        1 gttctttacc aatcacccta ntctcctgat tttaatccaa tagaacattg gtggtcacaa
       61 ctcaaagctt ttctacgtca gttttctcca accaattcga naatggttga tgtnctgatt
      121 agaactgccc tcgatntagt caatcccaag catttaaaaa actggttcac aagntgttgt
      181 tactgtacct cacttacctg aaaagtgctg taagtaacaa gtaacaagca ataagtaaat
      241 ctctagtcct cagttcctaa tcaccgtatg gtactgtcac ataacgtcat cagtacgcag
      301 ttcctgcgga gccactagca acgcttaacg ccaataaata accaatcaat ccctatatga
      361 cgctgtcgcg tcacataata cctatagctg cgctacctac ggttaagccg caatccggta
      421 cgctaagcta gcaacgctaa cgccaatcgc tatatgacgt atttacgttt agaaggaatt
      481 accaaacgtt ttggttcatt tactgccaac gataatatca gcttcagtgt tgaacaagga
      541 aaaattcatg ccatccttgg tgaaaatggt gctgggaaaa gcacattaat gaatattatc
      601 agcggtctat accaagcaga taaaggtcaa atatacattc aagaaaaacc agtcaaaatt
      661 aagtcttcaa gtaacgccat aaaattgggg atcggcatga ttcaccaaca ttttatgctg
      721 ataccacagt taactgtgac agaaaatatt attctgggaa caaaaattaa ttggcgttta
      781 aatatattcc aaagacaaca ggaagtagca gatttatctc gagcctacaa tttggatatt
      841 aatcctggtg ctaaagtcgg agacttacct attggtgttc aacaaaaagt agaaattctc
      901 aaagttcttt accgtcaagc aaaattactc attctggatg aaccaactgc agttctaacc
      961 ccatcggagg ttaactcatt catcaccatt ttgcgccgat tagcagacaa tggaaaaaca
     1021 attattttta tcagtcataa attagaagaa gttattaatc tttgcgatac ggttacagta
     1081 ttacgcagag gtaaggtaat tacaaataca accacaaccg acgtgagtcc tcagcactta
     1141 gcagacttaa tggtgggaca taaggttgct ttaaacttag ataaacccca gacattccca
     1201 ggagaaatag tcctatcagc aaagaattta tacattaaag atgaccgggg tattaatact
     1261 gtttgtgata tatcttttga actgagagcg ggagagataa ttggtattgc aggtgtggat
     1321 ggaaatggac agcgagagct agcagatgga atttgtaggt tacggactat cgagaaagga
     1381 aaactcgaat tcgagcaaaa ttgcaccatc ctagcttata ttcctgaaga tagacaaaaa
     1441 atgggtttgg tactagagtt taatatctcc caaaacttaa tattgaaagc atttagcaaa
     1501 ataccttttt gccgtcgttt tttattacaa caacaagcca tcagagacca tgcaatatct
     1561 gcattcgatg catatgatat tcgtgctcaa aattctgaag ttaaggtcaa acaactatca
     1621 ggaggtaatc aacaaaaaat agttttagca agggaattaa atcaaaaacc aactttaatt
     1681 gtggcgatgc agccaacacg cggtttagac atcaatgcaa cccaagcggt ccaacagaag
     1741 ttactagctg aaaaagaacg tggggcggca atattgtata tttctactga gttggaggaa
     1801 ataatggcaa tgagtgacaa aattgctgtg atgtatgaag gtcacttcag caaattacta
     1861 gattctgcta cagcacaggt ggaagaaatt agttttttaa tggctggtgg taaaaagtgg
     1921 gagaaaaatt caaagtaaat caaatgcact cagcaatttt caataattca ttgtcatttt
     1981 attcattaat tatcagctat taattgtcaa acaataatat ttaatgactg taattttagt
     2041 gggtgataat tttttattat ctagattttt tatcctgaat ttcctttaaa ataagtagca
     2101 ccaagtaaat aatggcaaat ttcgcgttcg gggttataat tgtagccata aaaatttaac
     2161 taatcctcct aactaggcgt tacttataaa aagtaagtta atttctgggt taaggtgctg
     2221 taatctaatg atggtgcact gtttccaaaa gtacgagttt tcaattcaat atttattcga
     2281 taacatgttt gttcgagtaa atatttgttc gagaaaattt gttcaagaaa ataatttgtg
     2341 caaatgcatt tttctttaag ggcgataaga ctctaccaaa ctaatagttc gtaaggaatt
     2401 atctataaat ttccttcgtg ttttattttg ttaccggaat atatttacca acttaaggtc
     2461 caaattgagt gctggaactg ggtactaggt gaagctaaat tcttgtatta tccataccca
     2521 gattcaattg cagagtccaa ctgtatcagt aattccaagt aatcacaaga tattgagcat
     2581 atgctaaagg cagaaaaata tccccaacag tttttaaatg tcaatgcagc ccagtcaaat
     2641 gatgctgatg aaggtggatt gaatctgggt cgagttggag ccgctcttcg ccgtcgagtg
     2701 ttattaattg ctgggatgac ctgtttggtc gcaacagcag cagttttaaa agcagaaata
     2761 gatccccgtt cttatcaagc tgagattgaa attctcacgg agtctttaag tgctgaagct
     2821 caagctgtag ctgatgttcc tcaaactctt gtttcccaga aaggtttaac ctcagttgca
     2881 aagggtaaaa atgtcaaaac caccattaag gttttaaaaa gtcggagggt tttgggacct
     2941 gtagtaagac aactacaagt taaatatccc gaaattgatt atgagtacat cgcttctagt
     3001 ctgaagatag aatctacaga aaaacatatt attactgtcc agtttataga ccttagagaa
     3061 gaagtagtaa ctgatgtttt aaatgccatc aaagatactt acttgaacta tagtctagaa
     3121 gagcgacgga atgatgttca agaggcgatt aagtttgtag aacagcagaa aaagccttta
     3181 gaaaaacgag ttcgagaatg gcaagataag ctgagaagaa tccgccaaac taataatatg
     3241 gtcgatccta ctcagaaagc ccaggaagta tcggctcata ttacgagtct caatcagcag
     3301 cttttgcaaa accgggtaca gttagaacag atgttcgcaa aatatcaagg tttgcaaaga
     3361 gagctagccc agcaaccagg gagtttggcg agtaacccga ttctgagtga aaatcccaat
     3421 tatcaaaata tattggttca aatttttcaa gtcaatgccg agattgctaa aaggtcatcg
     3481 gtatatacag acgtagatga aggaatgcaa cgactccggg accaaaaagc taacatggtt
     3541 gctttactgg agcaagaacg tcaacgagta aatcgagatt tccaaagtcg gattcaagaa
     3601 ctacgaagtc gtgatgcttc tctggttcag aaaatcaatt atctaaatac gtatatgagg
     3661 ggactagctg ctgttagtcg cgattatgat aatatccagc gggaattaca aattgcaacc
     3721 caagcactaa atcaatttac agaaaaacaa caagcattac aaattgaaca tgctcaaagg
     3781 ttgcaacctt ggaagatttt agacccagag ttaactgaag ttaatagtcc caaagctttt
     3841 tctgcgagca ccaagatcaa cttaattttg ggtagtatgt tgggtatgct tttgggcgta
     3901 ggttctgctt tagtagtaga caaactcagc aacgtcttct atacatccaa agatctcaaa
     3961 gaagctgtca agttaccact cttgggtgtg gttcccttga gaagagagtt agcgacatta
     4021 tcatcttcgc aaaaccaaaa tttaattcct ggaattcaac cagcagctcg ggcttcattt
     4081 tttgaagttt tccgttctct atacaccaac attctgttac ttggctccga tacgccaatt
     4141 cgttccttag ttattagttc tgcatcccaa gaagaaggta aatcaaccgt tgcaatccac
     4201 ctagcattat cagcagcagc aatgggacaa agggtgctct tggtcgatgc gaacctgcga
     4261 aatccgactt tgcacaagca cttgggattg atgaatattc aaggtctaac ggacgttatt
     4321 tcttctgagt tggagtggag taacatcatt gagcgatcgc ctgctgagga aaatctctat
     4381 atgatgagtg ctggtccagt tcctccagat tctatccgct tactagcctc ggaaaaaatg
     4441 caggatttaa tgaacgacct tcaagcttca ttcgacctcg taatttacga tactcctcct
     4501 ctagtaggtt ttgctgatgc taacctgtta gctgcaaaca ccaatggtat ggtgctagtt
     4561 gctgcattag gtaagctgaa gcggacagtg ttccaagaag cattagaaga actccagatc
     4621 tcgggtacgc cgattttggg agtggttgca aaccgttcca aagatacggt gcatggttcc
     4681 tacagttact atcagcagta ttacagacaa accatgaaag ccgaacgaat cagagattca
     4741 caagaagctg gaacaacagt tagttaacag ttaacagtta acagttatca attaagttgt
     4801 taggtaacag ttaactgttt ataactaacg ctaagtgctt gcaggttaca cttaacagcg
     4861 atcggttacc aattaccaat tcccgatcgc tttaaatata acaactagcc aatccaaagt
     4921 atttaatctg aagactttag ggcgtcatct aagacttgac gtgcatcttg agctttagct
     4981 ttagcttgtt gataacgcat atttgcttga gcaaaagttt tgagaacttt aaaaccttct
     5041 ttcaggtgag caatttcttc ttgagttact gattcatcag tgaaaagaat atcaattgct
     5101 ttacgaactt ctaatgcttc actgcgcgaa tcctgaactt tcaatttcag tgttgctaaa
     5161 ttacttaaaa tttgtacggc ttctgtaatt ttgtcttctt tactagtatt atccaaggct
     5221 gattctttta cttcaattaa ttgttgtgga ctgaaaccgt cttctaagtt ggtaggaagc
     5281 tcaccagaat ccatcatttc catcaactta tccatagctt tttccctggc tttatttgag
     5341 tccttaccgg gaactgtgag aattacctct gggctttgtg ctagagtata ctgaaccata
     5401 tctaaataat taggttattt atttttgcca actaaaggag ataattttac cctaaaaatt
     5461 tgtcaaaata tttagaaatg gtttttttta aggaaaattc gttatttatt atatttttac
     5521 ttgtttgcac cacatatcaa gtaaatgcag gaagatgata acccctctgt tttaacgagg
     5581 ggtggaaata atcttcctag ataggtgtga tgaaatgtct ttactgtcac agacagaata
     5641 cagaataagt ctgtagatag tttttggcag atatctactc tgagggagtt aatatttttt
     5701 aataagcgtc ctctaaaata tctaaaatgc ctacaactct aattactggt gcatccggtg
     5761 gtattggtga agcttttgct cgagaactag cagcaaacaa aaatgagcta gttattgttg
     5821 ctcgttcgga agacaaactc aatcaactag cttctcaatt gcaagagcag cacaaaattc
     5881 gggtggaagt tatagtcaaa gatttaactg cacagtcagc aactcaggag gtatttgaaa
     5941 ccgttcaatc gaaagggata gccgtagata ccttaattaa caatgcaggt tttggagatt
     6001 atggtgaatt tgctcagaca gatggagaaa gacaaatcaa aatggtgcag cttaatatta
     6061 ttgcactaat ggatttaacc cataaatttc tccctcaaat gcagcagcgt cgttcgggaa
     6121 atatcattaa tgtttcttcg attgctggat ttcaaccaat accataccta tcagtttatg
     6181 cagcaactaa agcattcgta ctaagtttta gcgagtcact ttgggctgaa aatcgtcagt
     6241 atggagtgcg tgtacttgta gtttgtcctg gtcctacaga aacaaacttt tttgaagaag
     6301 ctaatttccc tagttctttt acaggtaaaa ccagcaaagt ttctactccc gaagaagttg
     6361 tacgtagtac cctcaaagcc ttagaagaag ataaatcaac agttgtaagt gcaggaaccc
     6421 tcggtaaaat catagttaat atgccaagat ttctacctcg ggaaacctta gttaatattt
     6481 tggaaaaaca gtttaaagcg taagaagtca gaagtcagga gtcaggagtt aagagttggg
     6541 agtcagaatt ttgattattg tctgtcccca ttacccatta ctcattacca atccccagtc
     6601 gccatatgcc gcttgcggcg gcacgcagtg ctatccttaa ttccccatca aacatacttt
     6661 gtcatctgca cgcggtaacg ttgttttttc gtaaccgcaa tatctccaat ttctaatctt
     6721 cctttacccc gtatagcaat cagatcgccg gattttatgg gagaactagc ttgagatatt
     6781 tctttccagt taacccttac atctccacct gagattagat cgaccatctt actgcgggac
     6841 atcccaaaac cagcagatgc aacagcgtct aatcgtaaag atgcttctac tgtagtcatt
     6901 tcttttttct tgggttgacg aatttttaat tcactcaagt ctatacgttg ggttttgacg
     6961 ggaaccgaac gcacttgggt taaattcatt tctagaaact ctaccatttc cggcacaact
     7021 attgcttgtg ctccgcgttc tcccaaaaca ataatatctc ccgttttttc ccggacaatt
     7081 ccggttccca acattgaacc taaaaagtcg cggtgggttg ctgtatcaaa cagaaaatta
     7141 cccgcaatat ccaatactgc aatttcaact tgagattggt ctaatggtag atcagaacgt
     7201 gcgatcgcaa ttctacagcg ttcggcttgg ggatacccgc cccaaataat caattctacg
     7261 tcggttaaac gctgaaaaat ttctcttatt tctgccaatt ctggtggtga gagaaaatca
     7321 gttaaaacta cttcccaggt cttaatcgct tgctcagccc gatctattac atgagctata
     7381 gtttctcgat tttcgacacc ctttaacaat tcttctcttg gcaacattac agacaaatat
     7441 ttaattatca ataaattggt tcttttcgat tttagcgctc gtattctcaa aatttacatt
     7501 ttcactctgg ttatattagg acttctgttg actattatct cttcttgctc cccagtaccc
     7561 acagtgctgt gctttagcta ttaatcttaa atatctaaat agtttctcgc tttctccaag
     7621 gattatttag tacatggtag agataaaaat accccaacag tttgtcgggg aaattaggaa
     7681 tatttgcaca agaacgcgta tatataaaga gtatctggtt tacaaattaa attgttgcca
     7741 ttttggcagc tatcaatgtg ttatcaattc agaaacagtg tttcgaattt aattatagtt
     7801 atgtaaagct tttagatgtg ctttttgtaa gggtttaaag gatttaaagg atagtgttaa
     7861 gttaaaattc taatactgta ctgacttatg aataaaaatt tttgttacaa gtaattaacg
     7921 aacctaatct tataccagga tttatatctt atttgcagga aagaattaat acacatcaca
     7981 gcagaagtca ggagtcaggg gtcagaaatc agaagttaga atagtgcgca atagcgcacc
     8041 gctttgccaa cagaagttgg aagtcagaag tcagaaatca gaaatcagga tttaggagcg
     8101 taatcctttt gatgacagac tttcagattt tgaaatttac ctcacttact ttagaatctg
     8161 ctacggaggg actcacagtt caaaactcga ttacagactt attgattgtt tcctaccgtt
     8221 cgcaacaaat aaaacaacaa taattgcggt tgtaatagtt gtagcagtaa tcttctcgcc
     8281 caaaagtaca gctgaaaaca aaatagtcat aaatggttgt aataactgca gttgtccgac
     8341 tctagctatc ccacctattg ccagtctatg gtaccaagca aagaaagcaa gcaacatgct
     8401 caccacgcca acatagataa aatctaacca agctgtatat gaaggagaag gtttatggtc
     8461 tgggagcgga gccggaacag ggttaatctt tggatttata ccagaattga aaaatgacct
     8521 ctacttttaa ttccgaacct tatggtaaaa acccgtattt tattgtctag aataaaacaa
     8581 aaacctccca tcgatggcga actctaataa ccccaacgat ataattaaac gcattctcaa
     8641 cggaattcaa actgatgatg atgtggaagc tttacgtcag ttgcttctag caggcgatcg
     8701 cgcagcgact ccggaggagt atcgccaagt tttacaacaa ctcagcaaat acaatgtcaa
     8761 tatcacagag gcaaaagaaa ttcacattgg cgatcgtaac tactactctt ggaatgaaga
     8821 agccctcagt gccttagttc atatgattcg cttccatcag tctgacgatg ttgatacagc
     8881 taatttatta gtcaccaaac ttaataatgc ccgattacaa ggagaagaag gcgatcgcaa
     8941 gacaggtagt ttttatacct ataacgtttg gttagaagac gtctgtctgg aaaaatccaa
     9001 cgactccact gaaaataatt gctgtaccca acaatacact atcaaaggaa aatgggattc
     9061 aaaagtttac aaagaagtca atatgtttgg tttacgggtt gataagcctt ggggactcaa
     9121 gaaaaaaccc cacggaaatt ttactgttac agttgaaatt ctcaatggaa gagccaccca
     9181 agttaaagtt gatgtagttc gatatgatga tagtgcaaat aactacgcag cagacaaagc
     9241 taaacaatta attaactcga aaataagggt tgtgttgcaa aaattagaga tgatgagata
     9301 accttgggca aaagttctgt ggggtttggc agcttgcgaa acagacttaa cgggaaaagt
     9361 cagcgttgtc ttgcagtgaa gtgggaacgt caaaatattt gttttaactc tttctctacg
     9421 agacgctgca caaacataga cattgcaact ttcacctcca tcttattact aggataggtt
     9481 caataaaaag cacaagtttt aagtcaagct tatttgcaag cctccttgta tttttaatag
     9541 acgcaattga ggtcaactta tgtacttaac atatatgcga tactcccttg caactcctca
     9601 acccgccggg gtctgaggtg ggacctgggc agactagact gccacctggg gcaggactat
     9661 cgacaacctg gttgatgccc atgggtttca ttggaactgg gtaggtaagt ctagcaagca
     9721 tattccgttc gattggaccg gtccttcata aggacttttt gggtggagac aggtcgtcag
     9781 aagtagggtt gaaggaggaa agatggggcg ggctacaccc cttgaggtga tactgaggcg
     9841 agaccggctg gttataatgg tcggaatttt gggtctagtg gcgttatcgt gggcgtatat
     9901 cgtctacttg gcgttgacca tggaaaacac gatggcttcc atggggacag aggtgtttat
     9961 gtctcagaca tcgccttggg gcacgataga atttgttcta atgtttgtca tgtggactgt
    10021 gatgatggtg gctatgatgc tgctcacagc tgtgccgatg atattggtat tcgccactgt
    10081 cagtcgcaga cgccaagagc aacggagacc gtttgttgcc acaagtatgt tccttgtagg
    10141 atacgtggtg atttggagtg gattttcgct tttggccact ttagccaatt gggaactcca
    10201 tttacccatt gatgtaccag agctagtgta cttcatttac ctgcaatctg ctgtaacagt
    10261 tttttagctc ttccaacttc attcataccg catttatgca acgctattta agaagccatc
    10321 actcacgaaa tatgcaaagt aagtttcaag tagctttatg tctacagttg gaatacttac
    10381 atcggtatta gctaaactcg taagagtatt ttgacaatct attttctgat agttttgtga
    10441 tagctctttt tgttgctgta attgcgattt gaaattaaaa gaatatgcgt gcatagcatt
    10501 ttctggatga gcaattaact catttatcca cttgcttaaa gatacctcct caagtgggta
    10561 acccaaagaa ctaatccatt ggaaaagatt tttggtggga gtggaattgg ggttgatcaa
    10621 gtggaaggct tttcccaaag attctttctg tagcgatatt tcacaaatag cttgacttac
    10681 aaagtcaaca ggaatcaagt tttctagact attgatattt ggtaccattc caagttgaat
    10741 acacccttta attatacgag agaagaaatc attagtatta ctaacacctg tttggctatg
    10801 tcctgttatc atagctggtc tgtaaatgct cgctggcaat cctcgctcac aggcttgcat
    10861 tactaatttt tctgcaaccc atttactttc gacgtagcca tttccaagac cttggctatt
    10921 ttctggaata tcggattctt gaattagttc aatctcagaa taagcttcag taaagaaaac
    10981 tcctatagta gaaatgaaat gtacgggctt agtacgatgt ttgctagcta accttaatac
    11041 ttcctgagtc cctaaaacat tggctcgctt cagtgtcaaa tagttataaa catgattaac
    11101 ccacgcacca ttatgataaa taacatcaat ctgattggct aattgattaa attgttgtgt
    11161 tggaagacct aaaagttgcg cagataaatc tccaacaata gggataatcc tagaactaaa
    11221 cttttcattc caaagaaaat gtgattcaag tttattttga agcttttgtt tcgctgattc
    11281 agcatttgca gaacgtacca aacagtagat atttgctgaa gttcgctcta aaagttcata
    11341 aagtaaataa gttcctaaaa atccagttgc tccagttagg aagatatttt tgggttccaa
    11401 aacgtagtga atgggtgctt gaggctgaat tgttggatct aagatggctt ctgcacttaa
    11461 atctaaggta actttagtgt aggttccttt ttgaagtatc gtatcaatgg ttccagctag
    11521 cccagctaca gtaggttctt caaacaagca acttacaggt aaatcgattt ggaaggtttg
    11581 ctgtaatcta gaagttaatt gggttgctag tagggaatgt cctcccaact caaagaagtt
    11641 atcctgaatg ccaacatttt ctactcctaa gacatcggca aagatattgg ctattatttt
    11701 ttcacttgaa gtacgtggtg ctacatattc ttgtttttgt aaagtaaaat caggttctgg
    11761 taatgctttt ctatcaactt tgccgttagg agttaacggt aaagaatcta agataataaa
    11821 aacgctaggc accatgtagt ccggtagctt tgacttgata aattcacgta tttgttgatt
    11881 acatagtgac tcttgagtta cgacataagc aactagatgt ttactaccac taataaatgg
    11941 tgcagtaact acagcttgat taacttgagg atgggtggct aagactgctt ctatttctcc
    12001 gagttcgata cggaaaccgc gaatcttcac ttggttatcg atgcgaccca tgaattcaat
    12061 atttccatcg ggtaagtaac gagcgagatc acctgttttg taaagacgtt tggatttgga
    12121 atttgagaag ggattttgga taaatttttc tgatgttagt tggggacggt tga
//
