LOCUS       c00282_3300005..        8103 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300005337.a:Ga0070682_100004088.
ACCESSION   c00282_3300005..
VERSION     c00282_3300005..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-24 03:34:21
            Original ID  :: 3300005337.a:Ga0070682_100004088
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 8103
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..8103
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2655:8103](-)"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(2656..8103)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..8103
                     /SMILES="NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..8103
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="(cds(Condensation and (AMP-binding or A-OX)) or
                     (Condensation and AMP-binding))"
                     /tool="antismash"
     CDS             complement(3..1892)
                     /gene_functions="other (smcogs) SMCOG1037:heavy metal
                     translocating P-type ATPase (Score: 425.2; E-value:
                     8.4e-129)"
                     /gene_kind="other"
                     /locus_tag="ctg282_1"
                     /transl_table=11
                     /translation="MSKPFPTRGRDAAGAPPPALAATLGHAFRSPEALLDALQSNPGGL
                     DAEQIRARLQRDGLNEVSREKPPHWSLQLLRAFRNPFIVVLLVLAGVQLATDGNDLTGP
                     LIIAVMVGISVLLSFTQEYRSSRAAEQLKAMVRNTATVRRRASDGHSEQIEVPVRELVV
                     GDIVQLAAGDMVPADLRLLGAKDLFISQAILTGESVPVEKAAPAATVPGVVDDPLELAS
                     VCYMGTNVVSGTASAVVLATGARSYLGSLAHSMAGARVQTSFDRGIRSVSWLLIRFMAV
                     MVPVVFVINGLDKHDWGEAFLFALSIAVGLTPEMLPLIVTANLSKGALAMSRRKVVVKR
                     LNAIQNFGAMDVLCTDKTGTLTLDRIVLERHLDLDGEASDQALEYGYLNSRFQTGLKNL
                     LDKAVLAHRDLEAAATRYRVVDEIPFDFQRRRMSVVLADGAGEHLLICKGAVEEMLSIC
                     AWAQTGGVIEPMTGERRRAIKAMTHSLNEDGLRVLVVAVRRQPAQAHAYGVADEEGLVA
                     VGCLAFLDPPKDSAATAIRALHQHGVAVKVITGDNEAVTRKICREVGLDVGESVQGRDI
                     ESLDDAALDALVARVTVFAKMSPLQKARVVRSLQRLGHTVGFLGDGINDAPALH"
     CDS             complement(1994..2221)
                     /locus_tag="ctg282_2"
                     /transl_table=11
                     /translation="MKLLHDFFRWPFAGVRAVASQPAALPRDFSVTVPAPLAGSASPSP
                     QTLEPSRNGRREPASFLRSPRRRRLGRAHR"
     CDS             complement(2656..8103)
                     /NRPS_PKS="Domain: Condensation_LCL (23-320). E-value:
                     6.3e-115. Score: 375.0. Matches aSDomain:
                     nrpspksdomains_ctg282_3_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (486-894). E-value:
                     4.7e-112. Score: 366.3. Matches aSDomain:
                     nrpspksdomains_ctg282_3_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (1002-1067). E-value: 1.1e-21.
                     Score: 68.5. Matches aSDomain:
                     nrpspksdomains_ctg282_3_PCP.1"
                     /NRPS_PKS="Domain: Thioesterase (1089-1318). E-value:
                     1.7e-20. Score: 66.1. Matches aSDomain:
                     nrpspksdomains_ctg282_3_Thioesterase.1"
                     /NRPS_PKS="type: NRPS"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     415.8; E-value: 4.3e-126)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg282_3"
                     /sec_met_domain="Condensation (E-value: 4.4e-79, bitscore:
                     253.3, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 1e-119, bitscore:
                     387.4, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 9.7e-13, bitscore:
                     36.3, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 2e-16, bitscore:
                     48.9, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="GFARCLADAAPATLPPMTRANRGERIPASFAQRRQWFLAQMDGAA
                     SAYHVPFGLRLRGRLDVQALRRALDGILARHESLRTTFFHVDGEPCQRLAPAQECRFQL
                     VEKVATDAAETARLANAAIMDRFDLERGPLIRGLLIREGEDLHALLITMHHIVSDGWSM
                     GIFISELGKLYETCVRGDENPLPPLELHYADYAAWQRQWVAGELLDKQGAYWKSSLAGA
                     PELLTLPLDRPRPPEQSYAGETVPLVLDRALTKALHAMGLRHGTTPFMTLLAGWAALLS
                     RLSAQDDLVVGTPTANRGRPELEGIIGFFANTLALRLDLSGNPSVATLLQRVKSCALAA
                     QEHQDIPFEQVVELVNPARSTAHGPLFQAAFSWESDGALRLELPGVVSEPLEGIHYKVA
                     KFDLSLSLRESEGRFEGALEYSTALFERETVQRMAGYYEALLRGMVENAERAVGAIPIL
                     GAAEYALVTETWNATATAYPADRCLHRFFEEQVARSPEATAVSFGGATLTYVELNRRAN
                     RLAHRLRSLGVGPDDRVALCMERGIGMLVGILGILKAGGAYVAMDPAYPEARLKHMLAD
                     SGPLALLVSGDPPEAVQQARGQIPVLDLGQAFTEQPDTDPAADEVGPGAGNLAYVIYTS
                     GSTGTPKGVMVEHRGVVNLIADWLRRFAASGNPPPAHASLWTSFSFDVSVFELFVPLSV
                     GATVHIVPDDIRGEPTLLLDWFVQHRIALAYLPPFFVRQLDELMANAGGKLPFAHLLVG
                     VEPLLESQLYRLQSSGADGEIRIVNGYGPTETTVFSSSYETMRDIHRNAPIGRPVANTR
                     IYILDGHRQPVPVGVTGELHIGGAGVARGYANLPELTAERFIRDPFRGEPDARMYRTGD
                     LARWMPDGNIEFLGRNDHQVKLRGFRVELGEIEARLMERPEIREAVVLARDGDAADKVL
                     VAYYVGSETLAAEALRAHLEERLPRYMVPLAFVRMDALPLLSSGKLDLRALPAPDLAPV
                     RAESEFVAPRNEQESRIAGIWSEVLGIPRIGINDNFFDLGGESFKAFRVIGRIGGGIGV
                     TELFKYPTVRQLAERISGSRAGSQGLLHELTRPVPANEKTLTLVCIPFPGGGPISYQPL
                     AREMPRGCTVLGLELPGHDYGRREEKPLPIGEIARRCAEEIARDVTGPLAIYGHCAGGA
                     LTIALARELEDRGIAISRLFIGGHFPTPHLPGKAFAFLRKILPIHKWASQRSSFDILKS
                     FGFFDEVTDVAQQEFVMTNFVSEHQEIEDFYTALYSAPFRKLKAPLTCVVGEMDRATEF
                     YQERYHEWEHFCGVVDFAVIPKAGHYFIKHQADDLGKIIRQGIGSGQDMPAVPSLPVAE
                     APQPVAPAPAGRPPAKSSLATFFTVAVGEIVSMIGSTLTSFALGVWVYQQTALVSTYAL
                     MMVFIILPAIALSPVAGTLADRIDRRKLMIASNCLAGFSTMSAAALIWFESLQIWQVYV
                     LAGLTAVANAFRLPAYASMITQIVPKRYYGKANGFVQLGAGMGSFIGPALAGALMGWIG
                     LDGIVLVDLTTFVIALATLLYVRIPDALFARREEPFFKEMVGGWHYIVKRHSLVAMIVM
                     VTIANYFVGLIESLITPLVLVSGNPESLGFVMASNGAGILVGSALMSLWGGTQRRIDGI
                     LACTLLCGFCIALAGAYPSVSSQASGMFGFGFALALVNAHWISTVQTKVGMELQGRVMA
                     TNFMLMEAMVPLGYLSAGPLADRVFEPLMAKGGAGAGVLGGIIGTGPGRGIGLILVLSG
                     VFLAMWAVAAYLYRPIRRLEDILPDARADEVIEADKDKLQEKADLALRLATRKEEGLAS
                     "
     aSDomain        complement(4150..4836)
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg282_3_Thioesterase.1"
                     /evalue="1.70E-20"
                     /label="ctg282_3_Thioesterase.1"
                     /locus_tag="ctg282_3"
                     /protein_end="1318"
                     /protein_start="1089"
                     /score="66.1"
                     /tool="antismash"
                     /translation="TLVCIPFPGGGPISYQPLAREMPRGCTVLGLELPGHDYGRREEKP
                     LPIGEIARRCAEEIARDVTGPLAIYGHCAGGALTIALARELEDRGIAISRLFIGGHFPT
                     PHLPGKAFAFLRKILPIHKWASQRSSFDILKSFGFFDEVTDVAQQEFVMTNFVSEHQEI
                     EDFYTALYSAPFRKLKAPLTCVVGEMDRATEFYQERYHEWEHFCGVVDFAVIPKAGHYF
                     IKHQADDL"
     aSModule        4150..8034
                     /complete
                     /domains="nrpspksdomains_ctg282_3_Condensation_LCL.1"
                     /domains="nrpspksdomains_ctg282_3_AMP-binding.1"
                     /domains="nrpspksdomains_ctg282_3_PCP.1"
                     /domains="nrpspksdomains_ctg282_3_Thioesterase.1"
                     /final_module
                     /locus_tags="ctg282_3"
                     /monomer_pairings="X -> X"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(4579..4647)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg282_3_0010"
                     /evalue="2.40E-05"
                     /label="NRPS-te1"
                     /locus_tag="ctg282_3"
                     /protein_end="1175"
                     /protein_start="1152"
                     /score="16.9"
                     /tool="antismash"
                     /translation="TGPLAIYGHCAGGALTIALARELE"
     aSDomain        complement(4903..5097)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg282_3_PCP.1"
                     /evalue="1.10E-21"
                     /label="ctg282_3_PCP.1"
                     /locus_tag="ctg282_3"
                     /protein_end="1067"
                     /protein_start="1002"
                     /score="68.5"
                     /tool="antismash"
                     /translation="ESRIAGIWSEVLGIPRIGINDNFFDLGGESFKAFRVIGRIGGGIG
                     VTELFKYPTVRQLAERISGSR"
     CDS_motif       complement(5392..5457)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg282_3_0009"
                     /evalue="5.50E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg282_3"
                     /protein_end="904"
                     /protein_start="882"
                     /score="37.6"
                     /tool="antismash"
                     /translation="FLGRNDHQVKLRGFRVELGEIEA"
     aSDomain        complement(5422..6645)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg282_3_AMP-binding.1"
                     /evalue="4.70E-112"
                     /label="ctg282_3_AMP-binding.1"
                     /locus_tag="ctg282_3"
                     /protein_end="894"
                     /protein_start="486"
                     /score="366.3"
                     /specificity="consensus: X"
                     /tool="antismash"
                     /translation="FEEQVARSPEATAVSFGGATLTYVELNRRANRLAHRLRSLGVGPD
                     DRVALCMERGIGMLVGILGILKAGGAYVAMDPAYPEARLKHMLADSGPLALLVSGDPPE
                     AVQQARGQIPVLDLGQAFTEQPDTDPAADEVGPGAGNLAYVIYTSGSTGTPKGVMVEHR
                     GVVNLIADWLRRFAASGNPPPAHASLWTSFSFDVSVFELFVPLSVGATVHIVPDDIRGE
                     PTLLLDWFVQHRIALAYLPPFFVRQLDELMANAGGKLPFAHLLVGVEPLLESQLYRLQS
                     SGADGEIRIVNGYGPTETTVFSSSYETMRDIHRNAPIGRPVANTRIYILDGHRQPVPVG
                     VTGELHIGGAGVARGYANLPELTAERFIRDPFRGEPDARMYRTGDLARWMPDGNIEFLG
                     RNDHQVKLRG"
     CDS_motif       complement(5545..5634)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg282_3_0008"
                     /evalue="7.70E-17"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg282_3"
                     /protein_end="853"
                     /protein_start="823"
                     /score="53.4"
                     /tool="antismash"
                     /translation="PVGVTGELHIGGAGVARGYANLPELTAERFI"
     CDS_motif       complement(6160..6219)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg282_3_0007"
                     /evalue="1.70E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg282_3"
                     /protein_end="648"
                     /protein_start="628"
                     /score="35.7"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGTPKGVMVEHR"
     CDS_motif       complement(6418..6459)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg282_3_0006"
                     /evalue="6.70E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg282_3"
                     /protein_end="562"
                     /protein_start="548"
                     /score="13.1"
                     /tool="antismash"
                     /translation="LGILKAGGAYVAMDP"
     CDS_motif       complement(6985..7098)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg282_3_0005"
                     /evalue="1.80E-19"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="ctg282_3"
                     /protein_end="373"
                     /protein_start="335"
                     /score="62.1"
                     /tool="antismash"
                     /translation="CALAAQEHQDIPFEQVVELVNPARSTAHGPLFQAAFSWE"
     aSDomain        complement(7144..8034)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg282_3_Condensation_LCL.1"
                     /domain_subtype="Condensation_LCL"
                     /evalue="6.30E-115"
                     /label="ctg282_3_Condensation_LCL.1"
                     /locus_tag="ctg282_3"
                     /protein_end="320"
                     /protein_start="23"
                     /score="375.0"
                     /tool="antismash"
                     /translation="ERIPASFAQRRQWFLAQMDGAASAYHVPFGLRLRGRLDVQALRRA
                     LDGILARHESLRTTFFHVDGEPCQRLAPAQECRFQLVEKVATDAAETARLANAAIMDRF
                     DLERGPLIRGLLIREGEDLHALLITMHHIVSDGWSMGIFISELGKLYETCVRGDENPLP
                     PLELHYADYAAWQRQWVAGELLDKQGAYWKSSLAGAPELLTLPLDRPRPPEQSYAGETV
                     PLVLDRALTKALHAMGLRHGTTPFMTLLAGWAALLSRLSAQDDLVVGTPTANRGRPELE
                     GIIGFFANTLALRLDLS"
     CDS_motif       complement(7153..7242)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg282_3_0004"
                     /evalue="7.60E-17"
                     /label="C5_LCL_267-296"
                     /locus_tag="ctg282_3"
                     /protein_end="317"
                     /protein_start="287"
                     /score="53.6"
                     /tool="antismash"
                     /translation="DLVVGTPTANRGRPELEGIIGFFANTLALRL"
     CDS_motif       complement(7498..7533)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg282_3_0003"
                     /evalue="4.40E-05"
                     /label="C4_LCL_164-176"
                     /locus_tag="ctg282_3"
                     /protein_end="202"
                     /protein_start="190"
                     /score="16.0"
                     /tool="antismash"
                     /translation="HYADYAAWQRQWV"
     CDS_motif       complement(7582..7647)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg282_3_0002"
                     /evalue="4.50E-12"
                     /label="C3_LCL_132-143"
                     /locus_tag="ctg282_3"
                     /protein_end="174"
                     /protein_start="152"
                     /score="38.3"
                     /tool="antismash"
                     /translation="MHHIVSDGWSMGIFISELGKLYE"
     CDS_motif       complement(7855..7968)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg282_3_0001"
                     /evalue="1.20E-19"
                     /label="C2_LCL_024-062"
                     /locus_tag="ctg282_3"
                     /protein_end="83"
                     /protein_start="45"
                     /score="62.6"
                     /tool="antismash"
                     /translation="SAYHVPFGLRLRGRLDVQALRRALDGILARHESLRTTFF"
ORIGIN
        1 tcgtgcagcg ccggcgcgtc gttgatgccg tcgccgagga agcccaccgt gtggccgagc
       61 cgctgcagcg agcgcaccac gcgcgccttc tgcagcggcg acatcttggc gaacacggtg
      121 acgcgcgcga ccagcgcatc gagcgcagcg tcatcgagcg attcgatgtc gcggccctgc
      181 accgattcgc cgacgtcgag cccgacctcg cggcagatct tgcgggtcac cgcctcgttg
      241 tcgccggtga tcacctttac cgccacgccg tgctggtgca gcgcgcggat cgccgtggcg
      301 gcggagtcct tcggcgggtc gaggaaggcc aggcagccga ccgccaccag tccttcctcg
      361 tcggccacgc cataggcatg cgcctgcgcc ggttgtcgcc gcacggccac caccagcacg
      421 cgcaggccgt cctcgttgag gctgtgcgtc atcgccttga tcgcgcggcg gcgctccccg
      481 gtcatcggct cgatcacgcc gccggtctgc gcccaggcac agatcgacaa catctcctcg
      541 accgcgccct tgcagatcag caggtgctcg cccgcaccgt cggccagcac caccgacatg
      601 cgccggcgct gaaagtcgaa cgggatctcg tcgaccacgc gatagcgcgt cgccgccgcc
      661 tccaggtcgc gatgcgccag caccgccttg tcgagcaggt tcttcaggcc ggtctggaac
      721 cggctgttga ggtagccgta ttccagcgcc tggtcggagg cttcgccgtc gaggtcgaga
      781 tggcgctcca gcacgatccg gtccagcgtc aacgtgccgg tcttgtcggt gcacagcacg
      841 tccatcgcgc cgaagttctg gatcgcgttg agccgcttga ccaccacctt gcgccgcgac
      901 atcgccagcg cgcccttgga caggttggcg gtgacgatca gcggcagcat ctccggggtc
      961 agccccaccg cgatcgacag cgcgaacagg aacgcctcgc cccagtcgtg cttgtccagc
     1021 ccgttgatca cgaacaccac cggcaccatc accgccatga agcggatcag cagccagctc
     1081 accgagcgga tgccgcgatc gaaactggtc tgcacgcgcg caccggccat gctgtgcgcc
     1141 agcgagccga gatagctgcg cgccccggtg gccagcacca ccgcgctggc cgtgccgctg
     1201 accacgttgg tgcccatgta gcagacgctg gccagttcca gcgggtcgtc gacgacgccg
     1261 ggcaccgtcg ccgcgggcgc cgccttttcc accggcaccg actcgccggt gaggatcgcc
     1321 tggctgatga acaggtcctt ggcgccgagc aggcgcaggt ccgccggcac catgtcgccg
     1381 gcggccagct gcacgatgtc gcccaccacc agttcgcgca ccggcacctc gatctgctcg
     1441 ctgtggccgt ccgaggcgcg gcgccgcacg gtggcggtgt tgcgcaccat cgccttgagc
     1501 tgctcggcgg cgcgcgagga gcggtactcc tgggtgaaac tcagcaacac gctgatgccc
     1561 accatcaccg cgatgatgag cggcccggtg agatcgttac cgtcggtggc gagctgcacg
     1621 ccggcgagca ccagcagcac cacgatgaac gggttgcgga acgcgcgcag caactgcagc
     1681 gaccagtgcg gcggcttctc gcgcgagacc tcgttcaggc cgtcacgctg caggcgcgcg
     1741 cggatctgtt cggcgtcgag cccgccgggg ttgctctgca acgcgtccag cagcgcctcg
     1801 gggctgcgaa acgcatgccc gagcgtggcc gcaagggcgg gcggcggcgc accggcggca
     1861 tcgcggccgc gcgtcgggaa tggcttgctc atcgggtgcg tccgggtaac gcgtggccgg
     1921 gaaagacgcg cgtggcgtca gcgaatgcgc agggcgcgga cggactgccc ggggcagcgt
     1981 ccgcagcggt ggatcatcgg tgcgcgcggc ccagccgccg gcgacgcggc gagcgcagga
     2041 acgaggccgg ctcgcgtcgt ccgttgcgcg agggttccag ggtttgcggc gaagggctcg
     2101 ccgacccggc caacggggcc ggcacggtca cgctgaaatc acgcggcaac gccgccggct
     2161 gggacgccac ggcacggacg ccggcaaacg gccagcggaa gaaatcgtga aggagcttca
     2221 tcggctcatc tcctggtaac gacgccgtcg gcgtcctcag gagtgggccg gactttccct
     2281 agtggaaagc accagccgac cgcaggcggt cgccgcaggc gttcaacttg ttgttgtgcg
     2341 gcgccggcac ccgaagcgag cggatgtcga cgttgcgact agggtaaacg tccatatgcc
     2401 ttggtttgtc aggactggaa gccgtgcggc gcagcgcgcc gcagggcgcg cgcattgtcg
     2461 tgccgcagtg caaaactgtc aatcgcaaga ccggccattg ccgcacgaaa tgtttgcggc
     2521 aatgcacccg gcccggcagc gacctgcggc acgaccgtcg cccgcccgac cgcacgggct
     2581 cggttgcgca tccgttccgg gcggcgacgc ggaccggaac ggacgaccgc cttgcgccgc
     2641 gggatcgacc ggcaatcacg acgccagccc ttcttccttc cgggtggcga ggcgaagcgc
     2701 gaggtcggct ttctcctgca acttgtcctt gtccgcctcg atgacttcgt ccgcccgcgc
     2761 atccggaaga atgtcttcga gccgccggat cgggcgatac aaataggccg cgaccgccca
     2821 catggccagg aacacgcccg acagcacgag gatcaacccg atgccacgcc cgggcccggt
     2881 accgatgatc ccgccgagca ccccggcccc cgcgccgccc ttggccatca acggttcgaa
     2941 gacccggtca gccagtggtc cggcactcag ataacccagc gggaccatgg cctccatcaa
     3001 catgaagttg gtggccatca cgcgcccctg gagttccatg ccgaccttcg tctgtaccgt
     3061 ggaaatccag tgggcgttga ccaatgccag ggcgaaaccg aagccgaaca tcccgctcgc
     3121 ctggctcgac acggagggat aagccccggc caatgcaatg cagaacccgc acagcaaggt
     3181 gcacgccaga atgccgtcga tgcgtcgctg ggtgcctccc cacaaactca tcaaggcact
     3241 tccgaccaga atcccggcgc cgttcgaagc catgacgaag ccgagcgatt ccggattgcc
     3301 ggagaccaga acgagcggcg tgatcagcga ttcgatgagc ccgacgaagt agttcgcaat
     3361 ggtcaccatc acgatcatcg ccaccaggct gtggcgtttg acgatgtaat gccagccgcc
     3421 caccatctcc ttgaagaaag gttcctcgcg tcgcgcaaac agggcatcgg gaatgcggac
     3481 gtacagcagc gtcgccagcg cgatgacgaa ggtcgtgagg tcgaccagca cgatgccgtc
     3541 gaggccgatc caccccatca gggctccggc cagggccggt ccgatgaagg aacccatgcc
     3601 cgcgccaagc tgcacgaagc cgttggcctt gccgtaataa cgcttcggaa cgatctgggt
     3661 gatcatcgac gcataggcgg gcaaccggaa ggcattcgcc accgccgtca gtccggcgag
     3721 gacatagacc tgccagattt gcaggctttc gaaccagatc agcgccgccg cggacatggt
     3781 ggagaagccg gccaggcagt tgctcgcgat catcagtttc ctgcgatcga tgcggtcggc
     3841 aagcgttccc gccaccgggg agagcgcgat cgccggcagg atgatgaaga ccatcatcaa
     3901 ggcataggtc gagaccagtg ccgtctgctg gtagacccac acgccgagcg cgaaggacgt
     3961 cagcgtgctg ccgatcatcg agacgatctc gccgaccgcg acggtgaaga acgtggccag
     4021 gctggatttc gctggcggtc ttccggccgg ggccggtgcg accggctgcg gcgcctcggc
     4081 gacaggtagc gacggcaccg cgggcatgtc ctgcccgctg ccgattccct gccggatgat
     4141 cttccccagg tcgtcggcct ggtgcttgat gaagtaatgc cctgccttcg ggatgacggc
     4201 aaagtcgacg acgccgcaga aatgctccca ctcgtggtag cgctcctggt agaactcggt
     4261 ggcgcggtcc atttccccca ccacgcaggt cagcggcgcc ttgagcttgc ggaacggtgc
     4321 gctgtagagc gcggtgtaga aatcctcgat ctcctgatgc tcggacacga aattcgtcat
     4381 gacgaattcc tgctgcgcga cgtcggtgac ctcgtcgaag aacccgaatg acttgaggat
     4441 gtcgaacgag gagcgctggg acgcccattt gtggatcggc aggatcttcc gcaggaacgc
     4501 gaacgccttt ccgggaaggt gcggcgtcgg gaagtgtcca ccgatgaaca gtcgcgagat
     4561 ggcgatgccc ctgtcttcca gctccctcgc cagggcgatc gtcaacgctc cgccggcgca
     4621 atggccgtag atggcgagcg gccccgtcac gtcgcgggcg atctcctcgg cgcagcgccg
     4681 ggcgatctcg ccgatgggca acggcttctc ctcgcgccga ccgtaatcgt gcccgggcag
     4741 ttcgaggccc agcacggtgc agcctcgcgg catctccctg gccaggggct gatacgagat
     4801 cggcccgccc cccggaaacg gtatgcagac gagggtgagg gtcttctcgt tcgccggaac
     4861 cggccgggtc agttcgtgca gcaggccttg cgatccggcc ctgctccccg agatccgttc
     4921 ggcaagttgc cgcacggtcg gatacttgaa cagctccgtc acgccgatgc cgccgccgat
     4981 ccggccgatg acgcggaagg ccttgaacga ttcaccgccc agatcgaaga agttgtcgtt
     5041 gatgccgatg cgcgggatgc cgagcacttc gctccatatc ccggcgatgc gcgattcctg
     5101 ctcgttccgc ggcgccacga actccgactc cgcccgcacg ggcgcaaggt cgggagccgg
     5161 caacgcccgc agatccagct tgccgctgga aagcagcggc aaggcgtcca tccgcacaaa
     5221 cgccagcggc accatgtaac gcggcagccg ttcctcgagg tgggcccgca gcgcctccgc
     5281 cgcgagggtc tccgagccga cgtagtaggc cacgagcacc ttgtctgcgg catcgccgtc
     5341 gcgcgcgagc acgacggcct cgcggatctc cgggcgctcc atcaggcggg cctcgatctc
     5401 gcccagttcg acgcggaagc cccgcagttt cacctgatgg tcgttgcgcc cgagaaactc
     5461 gatgttgccg tccggcatcc agcgcgccag gtcgccggtc ctgtacatcc gggcatccgg
     5521 ctcgccacgg aacgggtcgc ggatgaagcg ttccgcggtc agctcgggaa ggttcgcgta
     5581 gcctcgcgcc acgccggcgc cgccgatgtg caattcgccc gtcacgccca ccggcaccgg
     5641 ctggcggtga ccatccagga tgtagatgcg ggtattcgcc accggccgcc cgatcggcgc
     5701 attgcgatgg atgtcccgca tggtctcgta cgaactggag aacaccgtgg tttcggtggg
     5761 accgtagccg ttgacgatcc gtatctcccc atccgcgccg gacgactgca ggcgatacag
     5821 ctgggattcc agcagcggct ccacgccgac cagcagatgc gcgaagggga gtttgccgcc
     5881 ggcgttcgcc atcagctcgt ccagctggcg cacgaagaac ggcggcaggt aggccagggc
     5941 gatgcggtgc tgcacgaacc agtccagcag cagcgtcggc tcgccgcgga tgtcgtcggg
     6001 cacgatgtgt accgtcgcgc ccacggacag cggcacgaac aactcgaaca ccgacacgtc
     6061 gaagctgaag ctggtccaca gcgacgcatg cgcgggcggc gggtttccgg atgccgcgaa
     6121 ccgccgcagc cagtcggcga tcaggttcac cacgccacgg tgctcgacca tgacgccctt
     6181 cggcgttccc gtcgacccgg aggtgtagat cacataggcg agatttccgg cgccgggtcc
     6241 gacttcgtcg gccgccggat cggtgtcggg ttgctcggtg aatgcctggc cgaggtccag
     6301 caccgggatc tgtccgcgtg cctgctgcac tgcctcgggt gggtcgcctg acacaagcag
     6361 agccaacggg ccactgtcgg cgagcatgtg cttgagccgg gcctcggggt aggccgggtc
     6421 catcgccacg taggcgcccc cggccttgag aatgccgaga atgcccacca gcatcccgat
     6481 gccgcgctcc atgcagagcg ccacgcgatc gtccggcccg accccgagcg accgcaaccg
     6541 gtgggcgagc cggttcgcgc ggcggttgag ttcgacgtag gtgagggttg ctccgccgaa
     6601 cgagaccgcc gtggcctccg ggctgcgcgc cacctgctcc tcgaaaaagc ggtgcaggca
     6661 acgatcggcg ggatacgctg ttgccgtggc gttccacgtt tccgtgacca gcgcgtactc
     6721 ggcagcgccg aggatcggaa tcgccccgac cgcccgctcg gcgttctcga ccatgcctcg
     6781 cagcagcgcc tcgtagtatc cggccatccg ctgtacggtt tcgcgctcga acaacgctgt
     6841 cgaatactcc agcgcacctt cgaaccgtcc ctccgactcg cgcagggaca gcgacaagtc
     6901 gaacttcgcc accttgtagt ggatgccctc cagcggctcg gaaaccacgc cgggcaactc
     6961 cagccgcagc gcgccgtcac tctcccagga gaacgccgcc tggaacagcg gaccgtgcgc
     7021 cgtgcttcgg gcaggattga ccagctccac cacctgctcg aaggggatgt cctggtgctc
     7081 ctgcgcagcg agcgcgcagg acttcaccct ttgcagcagc gtggccacgc tggggttgcc
     7141 cgagagatcc agccgcaacg ccagcgtatt ggcgaagaag ccgatgatcc cttcgagctc
     7201 cggccgcccg cggttcgccg tgggcgtacc cacgaccagg tcatcctgcg cggagagtcg
     7261 ggaaaggagc gctgcccatc cggccagcag cgtcatgaac ggcgtggtcc cgtggcgcag
     7321 gcccatcgcg tgcaaggcct tcgtcaatgc gcgatcgagt accagcggca ccgtctcgcc
     7381 cgcgtaactc tgctccggcg gccggggccg atcgagcggc agggtcagca gttccggcgc
     7441 gccggccagc gacgacttcc agtacgcgcc ctgcttgtcg agcagctcgc ccgctaccca
     7501 ttgccgttgc cacgccgcgt agtcggcgta atgcagctcc agcggcggca gcgggttctc
     7561 gtcgccgcgc acgcaggtct cgtagagctt gccgagctcg ctgatgaaga tgcccatcga
     7621 ccagccatcg gaaacgatgt gatgcatggt gatgagaagt gcatggaggt cctcgccctc
     7681 gcgtatcagc aggccgcgaa tcagcgggcc gcgttccagg tcgaagcggt ccatgatcgc
     7741 ggcattggcc aggcgcgcgg tttcggccgc atccgtcgcc actttctcca ccagctggaa
     7801 ccggcactcc tgcgccggcg ccagccgctg gcagggttcg ccgtcgacat ggaagaacgt
     7861 ggtgcgcagc gattcgtggc gcgccaggat gccatcgagc gcgcggcgga gcgcctgcac
     7921 atcgagccgc ccccgcagcc tcagaccgaa cggcacgtgg tacgccgagg ccgcgccgtc
     7981 catctgtgcc aggaaccact gccgacgctg cgcgaaggag gcgggtatgc gctccccgcg
     8041 attcgccctt gtcatcggcg gcagcgttgc cggcgccgcg tcggcgagac agcgagcaaa
     8101 ccc
//
