LOCUS       c00004_3300005..        6669 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300005805.a:Ga0079957_1011362.
ACCESSION   c00004_3300005..
VERSION     c00004_3300005..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 07:28:52
            Original ID  :: 3300005805.a:Ga0079957_1011362
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 6669
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..6669
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1818:6552](+)"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1819..6552
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
     cand_cluster    1..6669
                     /SMILES="C([*])C(-O)"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="single"
                     /product="T1PKS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..6669
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T1PKS"
                     /region_number="1"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /tool="antismash"
     CDS             2..1705
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Trp_halogenase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1119:halogenase (Score: 276.9; E-value: 5.8e-84)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_1"
                     /sec_met_domain="Trp_halogenase (E-value: 1.1e-13,
                     bitscore: 37.8, seeds: 23, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="NIKIALIDPRPEERTNKDLKIGESMVEIATLFVCKELGLYEYMIE
                     NHPPKYALNFHWAKDADKTDTIDDYYHIWANRQFPLGTFQMNRAKFERDLLKMNKKMGA
                     SFYQGRVVDVDITPTDEMHTVKVKMIDGNYHELRAKHLVDAAGRKFIIGHKTDNVIVGA
                     DNLFGVDTGSAWVRVKNIDRTIFHDGYDPYGATCSHYYATNHWFGHGHWLWMIPTEKDS
                     QEISIGIAQHRSVIANDQINTQEKFYAFLKANHNLLYRLVTSGENVDFHYLPRVSHTSK
                     TMFSQDNWYVVGDAACIFDPFYSLGTSMIAFAIESITEIIRSQLAGEADTEEKRAAYND
                     FNLTYTRLNNHLIEHHDKQLGHASIMSWRIYAEYMWWFGIQIPLYVGKWHLDTGFISRY
                     VPKVQADIKGYWHHLYEQFNQLVEQNKNIGFMDAHRTDQLIWGYHTLKHFDDFIENTKF
                     EPRRCNVFAGIKATSFYTAVWYAKFLWKGFGFSAFLNPKNLSYLFGHLNGAVQSAITEM
                     VYKYLTRKLSDNSQIEQTRQEFTNYRYRPQLNPWVKKEVKRSPEKIPIIV"
     CDS             1819..6552
                     /NRPS_PKS="Domain: PKS_KS(Hybrid-KS) (3-426). E-value:
                     1.2e-187. Score: 615.7. Matches aSDomain:
                     nrpspksdomains_ctg4_2_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (528-826). E-value: 1.2e-110.
                     Score: 361.3. Matches aSDomain:
                     nrpspksdomains_ctg4_2_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_KR (1172-1352). E-value: 3.8e-64.
                     Score: 207.7. Matches aSDomain:
                     nrpspksdomains_ctg4_2_PKS_KR.1"
                     /NRPS_PKS="Domain: ACP (1452-1522). E-value: 9.7e-19.
                     Score: 59.2. Matches aSDomain: nrpspksdomains_ctg4_2_ACP.1"
                     /NRPS_PKS="type: PKS-like protein"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     hyb_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1093:Beta-ketoacyl synthase (Score: 103.1; E-value:
                     2.4e-31)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_2"
                     /sec_met_domain="PP-binding (E-value: 2e-17, bitscore:
                     50.8, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 4.7e-112, bitscore:
                     361.3, seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="hyb_KS (E-value: 1.7e-196, bitscore:
                     640.2, seeds: 33, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 1.4e-61, bitscore:
                     194.6, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKPIAIIGIGCRFPKANNYHEFWQLLSKGIDGITEIPKERWNIDE
                     YYDENPETQGKMNSRHGGFLSQVDGFDPNFFGISPREALLMDPQQRLLLEVAWETIEDA
                     GITREQLAGSKTGVFVGIATNDYSRIHAGYSHHPQGYDLTGNCTNIAAGRLSYLFNLKG
                     PSLAVDTACSSSLVAVHLACQSLWNDESSMAIASGVNLILSPIGNIALSKLKALSPDGR
                     CKTFDESANGYVRSEGVGCIILKPLAQAIADNDSIYALIRGTAINHDGRSKGLTVPYGP
                     AQESLVRSALKNAEIEPKELNYVELHGTGTSLGDPIEAIALGSVLEEGRDKDNPCLVGS
                     VKSNIGHLEAAAGIASVIKMALSLKNKQIPPSLHFNKPNPYIPFDKLPLKLQSSLITWP
                     QQETTAKVGISSFGFSGTNAHLILEEANLSHQEPIALTFPHLLPLSAHSQEAVRDLAQN
                     YEYFLKDQALTPEFVQNLCYSASIRRTHHAHRQAVVVHSPEELLKGLKELETIDLSTQS
                     KPSKRKTNIAFVFSGQGPQWWAMGRELLATEPVFRSVIKQCDTLIQKYANWSLLAEFNA
                     SEAQSRLQETEVSQPALFALQVGLAKVWQSWGINPKSVVGHSLGEVAAAHFAGILTLEE
                     AIHLICQRGQLMQQATGNGKMLAIELPVNEVENLMAAWENKLEIAAINSPYSTVVSGES
                     QSIDQLIAELSQNHPHIFYKELPVNYAFHSQQMTTFADNLVKKLGELQPQKSTIPIFST
                     VTGDQQEGTLFNAAYWGQNMRQTVRFNPAIEAMIKSRHTIFVEISPHPVLLGYIKSTLR
                     EQDTEGFVLPSLRREHSERGTLLNSLGKLYTWGHSINWEKLYPENCQFVKLPLYPWQHE
                     SYWVSDAKPQFKSVSSASSLLNLLVEGKTEQLTEQLNQSDQLSPEVKQFLPQLLQLLVG
                     EDTTIAGQMPILQDVSKNCYKVEWQLSPLNLKNKPSQGERWLIFNDNQVVGKALATTLN
                     DAYVLVSSGQTYQKLVSGHYQINPNNVKDFQRLLQDLTEPITKVVYLWGLDSDINSQPS
                     QTRSYASLLYLTQALAQFKTKEPPKLWVITQQAQPVNDAVKPLKIAQTSLWGMGQVIAL
                     EYPNLWGGLIDLEEKQPSSQAIIAEITENLGEDRIAFRDHQRYVARLVPNKAIKSSNIN
                     FKKTEASYLITGGLGSLGLSLADWLIEKGANHLILTSRRALADHSTDKQVKIKALEDKG
                     ATIQVIAADVSDHQQTRQLFHQIQENCPPLQGIIHAAGVLSDRTIDKMDFHCFESVFNP
                     KAAGAWNLHQLSQDLSLDFFVCFSSMSALIGSRGQIHYAAANHFLDGLMHYRRESGLTG
                     LSINWGPWAQGGMATQGYEEGLKRLGINPLQPNLALDTLDALINGNVTQTMVAEIDWSK
                     FKTIVAAKGRVAFLEALFKQDQDNFVQTVENFPQTIQKKPPHRRVTLLTTRLQQEVAQV
                     LGIHGDTLPDTDKGFFEMGMDSLMSVELKHRLEGLFSVSLPSTFAFEYPTIGDVVRYFV
                     QEVFAWQDNSENSQISSETESTDVVVLHQALAELESLSEVETEALMERELAELEALL"
     aSDomain        1828..3096
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg4_2_PKS_KS.1"
                     /evalue="1.20E-187"
                     /label="ctg4_2_PKS_KS.1"
                     /locus_tag="ctg4_2"
                     /protein_end="426"
                     /protein_start="3"
                     /score="615.7"
                     /tool="antismash"
                     /translation="IAIIGIGCRFPKANNYHEFWQLLSKGIDGITEIPKERWNIDEYYD
                     ENPETQGKMNSRHGGFLSQVDGFDPNFFGISPREALLMDPQQRLLLEVAWETIEDAGIT
                     REQLAGSKTGVFVGIATNDYSRIHAGYSHHPQGYDLTGNCTNIAAGRLSYLFNLKGPSL
                     AVDTACSSSLVAVHLACQSLWNDESSMAIASGVNLILSPIGNIALSKLKALSPDGRCKT
                     FDESANGYVRSEGVGCIILKPLAQAIADNDSIYALIRGTAINHDGRSKGLTVPYGPAQE
                     SLVRSALKNAEIEPKELNYVELHGTGTSLGDPIEAIALGSVLEEGRDKDNPCLVGSVKS
                     NIGHLEAAAGIASVIKMALSLKNKQIPPSLHFNKPNPYIPFDKLPLKLQSSLITWPQQE
                     TTAKVGISSFGFSGTNAHLILEEAN"
     aSModule        1828..6384
                     /complete
                     /domains="nrpspksdomains_ctg4_2_PKS_KS.1"
                     /domains="nrpspksdomains_ctg4_2_PKS_AT.1"
                     /domains="nrpspksdomains_ctg4_2_PKS_KR.1"
                     /domains="nrpspksdomains_ctg4_2_ACP.1"
                     /locus_tags="ctg4_2"
                     /monomer_pairings="pk -> pk"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       2305..2352
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_2_0001"
                     /evalue="8.70E-07"
                     /label="PKSI-KS_m3"
                     /locus_tag="ctg4_2"
                     /protein_end="178"
                     /protein_start="162"
                     /score="20.8"
                     /tool="antismash"
                     /translation="GPSLAVDTACSSSLVAV"
     CDS_motif       2494..2532
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_2_0002"
                     /evalue="2.30E-04"
                     /label="PKSI-KS_m4"
                     /locus_tag="ctg4_2"
                     /protein_end="238"
                     /protein_start="225"
                     /score="14.2"
                     /tool="antismash"
                     /translation="FDESANGYVRSEGV"
     CDS_motif       2725..2772
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_2_0003"
                     /evalue="3.60E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="ctg4_2"
                     /protein_end="318"
                     /protein_start="302"
                     /score="12.7"
                     /tool="antismash"
                     /translation="YVELHGTGTSLGDPIEA"
     CDS_motif       2833..2877
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_2_0004"
                     /evalue="2.50E-04"
                     /label="PKSI-KS_m6"
                     /locus_tag="ctg4_2"
                     /protein_end="353"
                     /protein_start="338"
                     /score="13.3"
                     /tool="antismash"
                     /translation="GSVKSNIGHLEAAAGI"
     CDS_motif       3400..3453
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_2_0005"
                     /evalue="9.00E-06"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="ctg4_2"
                     /protein_end="545"
                     /protein_start="527"
                     /score="18.1"
                     /tool="antismash"
                     /translation="FVFSGQGPQWWAMGRELLA"
     aSDomain        3403..4296
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg4_2_PKS_AT.1"
                     /evalue="1.20E-110"
                     /label="ctg4_2_PKS_AT.1"
                     /locus_tag="ctg4_2"
                     /protein_end="826"
                     /protein_start="528"
                     /score="361.3"
                     /specificity="Minowa: mmal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="consensus: pk"
                     /tool="antismash"
                     /translation="VFSGQGPQWWAMGRELLATEPVFRSVIKQCDTLIQKYANWSLLAE
                     FNASEAQSRLQETEVSQPALFALQVGLAKVWQSWGINPKSVVGHSLGEVAAAHFAGILT
                     LEEAIHLICQRGQLMQQATGNGKMLAIELPVNEVENLMAAWENKLEIAAINSPYSTVVS
                     GESQSIDQLIAELSQNHPHIFYKELPVNYAFHSQQMTTFADNLVKKLGELQPQKSTIPI
                     FSTVTGDQQEGTLFNAAYWGQNMRQTVRFNPAIEAMIKSRHTIFVEISPHPVLLGYIKS
                     TLREQDTEGFVLPSLRRE"
     CDS_motif       3568..3636
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_2_0006"
                     /evalue="1.60E-06"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="ctg4_2"
                     /protein_end="606"
                     /protein_start="583"
                     /score="20.9"
                     /tool="antismash"
                     /translation="QETEVSQPALFALQVGLAKVWQSW"
     CDS_motif       3640..3762
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_2_0007"
                     /evalue="2.60E-21"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="ctg4_2"
                     /protein_end="648"
                     /protein_start="607"
                     /score="67.9"
                     /tool="antismash"
                     /translation="GINPKSVVGHSLGEVAAAHFAGILTLEEAIHLICQRGQLMQQ"
     CDS_motif       3856..3894
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_2_0008"
                     /evalue="1.50E-03"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="ctg4_2"
                     /protein_end="692"
                     /protein_start="679"
                     /score="11.8"
                     /tool="antismash"
                     /translation="AAINSPYSTVVSGE"
     CDS_motif       4111..4155
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_2_0009"
                     /evalue="4.10E-04"
                     /label="PKSI-AT-mM_m8"
                     /locus_tag="ctg4_2"
                     /protein_end="779"
                     /protein_start="764"
                     /score="12.8"
                     /tool="antismash"
                     /translation="NAAYWGQNMRQTVRFN"
     CDS_motif       4198..4227
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_2_0010"
                     /evalue="4.10E-03"
                     /label="PKSI-AT-mM_m9"
                     /locus_tag="ctg4_2"
                     /protein_end="803"
                     /protein_start="793"
                     /score="9.8"
                     /tool="antismash"
                     /translation="FVEISPHPVLL"
     CDS_motif       5335..5433
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_2_0011"
                     /evalue="6.00E-17"
                     /label="PKSI-KR_m1"
                     /locus_tag="ctg4_2"
                     /protein_end="1205"
                     /protein_start="1172"
                     /score="54.1"
                     /tool="antismash"
                     /translation="SYLITGGLGSLGLSLADWLIEKGANHLILTSRRA"
     aSDomain        5335..5874
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg4_2_PKS_KR.1"
                     /evalue="3.80E-64"
                     /label="ctg4_2_PKS_KR.1"
                     /locus_tag="ctg4_2"
                     /protein_end="1352"
                     /protein_start="1172"
                     /score="207.7"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: (unknown)"
                     /tool="antismash"
                     /translation="SYLITGGLGSLGLSLADWLIEKGANHLILTSRRALADHSTDKQVK
                     IKALEDKGATIQVIAADVSDHQQTRQLFHQIQENCPPLQGIIHAAGVLSDRTIDKMDFH
                     CFESVFNPKAAGAWNLHQLSQDLSLDFFVCFSSMSALIGSRGQIHYAAANHFLDGLMHY
                     RRESGLTGLSINWGPWAQ"
     CDS_motif       5668..5697
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_2_0012"
                     /evalue="4.10E-03"
                     /label="PKSI-KR_m3"
                     /locus_tag="ctg4_2"
                     /protein_end="1293"
                     /protein_start="1283"
                     /score="10.6"
                     /tool="antismash"
                     /translation="PKAAGAWNLHQ"
     CDS_motif       5719..5829
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_2_0013"
                     /evalue="6.20E-21"
                     /label="PKSI-KR_m4"
                     /locus_tag="ctg4_2"
                     /protein_end="1337"
                     /protein_start="1300"
                     /score="67.0"
                     /tool="antismash"
                     /translation="LDFFVCFSSMSALIGSRGQIHYAAANHFLDGLMHYRRE"
     aSDomain        6175..6384
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg4_2_ACP.1"
                     /evalue="9.70E-19"
                     /label="ctg4_2_ACP.1"
                     /locus_tag="ctg4_2"
                     /protein_end="1522"
                     /protein_start="1452"
                     /score="59.2"
                     /tool="antismash"
                     /translation="RLQQEVAQVLGIHGDTLPDTDKGFFEMGMDSLMSVELKHRLEGLF
                     SVSLPSTFAFEYPTIGDVVRYFVQEV"
ORIGIN
        1 caacattaaa attgcactga tcgatcctcg tccagaagaa agaactaata aagacctcaa
       61 aattggcgaa tcaatggtgg aaattgccac cttatttgtt tgcaaagaat tggggttata
      121 cgaatatatg atcgaaaatc atccccctaa atatgctctt aattttcatt gggcaaaaga
      181 tgcagataaa actgacacca ttgatgatta ttatcatatt tgggcgaatc gacaatttcc
      241 ccttggcacg tttcaaatga atcgggcaaa gtttgaacgg gatttgctca aaatgaataa
      301 gaaaatggga gcaagtttct atcaagggcg tgtggttgat gtggacatta ctcctactga
      361 tgagatgcac accgtcaaag ttaaaatgat tgacggaaat tatcacgaac tgagagcaaa
      421 acaccttgtt gatgcagcag gacgtaagtt tattattggc cataaaactg ataacgttat
      481 tgtaggtgca gataatttat ttggagttga tacgggatcg gcttgggtac gggttaaaaa
      541 tatagatcgc accatttttc atgatggtta tgacccttat ggagcaactt gtagccatta
      601 ctatgcaacc aatcattggt ttggtcatgg tcattggtta tggatgattc ccacagaaaa
      661 agactcccaa gaaatctcta ttggcattgc tcaacatcgc agtgttatcg ccaacgacca
      721 aattaatact caagagaagt tttatgcttt cctaaaagcc aatcacaatc tactttatcg
      781 cttagtcacc tctggcgaaa atgtcgattt tcattatctt cctagagttt cccatactag
      841 caaaacgatg ttttctcaag ataattggta tgtagttgga gatgctgctt gtatttttga
      901 tcccttttac tctttgggaa caagtatgat tgcttttgcg attgaaagta tcacggaaat
      961 tattcgttct caacttgcag gagaagcgga tacagaagaa aaacgggctg cttacaatga
     1021 ctttaacctt acctatactc gattgaataa tcatctcatt gaacaccatg ataaacaatt
     1081 aggtcatgct agtatcatga gttggcgtat ttatgccgaa tatatgtggt ggtttgggat
     1141 tcaaattccc ctttatgtcg gcaaatggca tttagatact ggctttattt cccgttatgt
     1201 gccaaaagtt caagcggata taaaaggata ttggcatcat ctctatgaac aatttaacca
     1261 attagttgag cagaataaaa atattggttt tatggatgct catcgtactg atcaattaat
     1321 ctggggttat cataccctca aacacttcga tgactttatc gaaaacacta aatttgaacc
     1381 aagacggtgc aatgttttcg ctggaattaa agcgaccagt ttttatacag cagtttggta
     1441 tgcaaagttc ctctggaaag gatttggttt ttcagctttt ctcaatccaa aaaatctgtc
     1501 ctatctgttt ggacatctta atggcgcagt tcaatctgcc attacggaaa tggtctataa
     1561 atatttgact cgtaagcttt ctgataatag ccaaattgaa caaactcgcc aagaatttac
     1621 caactatcgt tatcgtcctc aactaaatcc ttgggtaaaa aaagaagtaa aaagatcgcc
     1681 cgaaaaaata cctattattg tctaaatttg ggttaatcac ttaggcatag gtaaaagata
     1741 acatcacaaa tcacaagata gcatctttta cctttaaccc tacgcaatta ctgtctatta
     1801 attacggata tctcaactat gaaacctatt gcaattattg gaattggctg tcgttttcct
     1861 aaagcgaata attatcatga attctggcaa ttattatcaa agggaattga cggcatcacc
     1921 gaaattccta aggagcgctg gaatattgat gaatattatg atgagaatcc cgaaacacag
     1981 gggaaaatga attctcgtca tgggggattt ttatcgcaag ttgatgggtt tgatcctaat
     2041 tttttcggga tttctcctag agaagcctta ttaatggacc ctcagcaacg cttactctta
     2101 gaagtagctt gggaaaccat tgaagatgca ggaataacac gggaacaatt ggcaggatcg
     2161 aaaacaggtg tatttgtggg aattgccaca aacgattata gtcgcattca tgcaggatat
     2221 agccaccatc cccaaggcta tgatttaaca ggaaactgca caaatatcgc agccggtcgt
     2281 ctttcctatc tttttaactt aaaaggtcct agtttagcgg tagatacggc ttgttcttcc
     2341 tctttggtcg cagtgcatct cgcttgtcaa agtttgtgga atgatgagtc ttcaatggcg
     2401 atcgcatcag gggttaacct gattttatcc cctattggta atattgcgtt aagcaaattg
     2461 aaagcgttgt ctcctgatgg acgttgcaaa acctttgatg aaagcgccaa tggatatgtg
     2521 cgaagtgagg gagtcggttg tattattctc aaaccgttgg ctcaagcgat cgcagacaat
     2581 gattccattt atgcgttgat taggggaact gctattaatc atgatggacg cagtaagggg
     2641 ttaacggttc cttatggacc agcacaagaa agcttggttc gatcagcctt gaaaaatgca
     2701 gaaattgagc caaaagagct taattatgtg gaattgcacg ggactggaac atctttaggc
     2761 gatcccatcg aagcgatagc cttgggatct gtgttagaag aaggacgaga caaggataat
     2821 ccttgtttgg tgggatcggt aaaaagtaat ataggacatc tcgaagcagc ggcaggaatt
     2881 gccagtgtga ttaagatggc actctccctg aaaaacaagc aaattccgcc cagtctgcat
     2941 tttaacaagc cgaatcctta tattcccttt gataagttac cccttaagct tcaatcatct
     3001 ttaattacct ggccacaaca ggaaacaacc gccaaggtgg gaattagttc ttttggattt
     3061 tcgggaacaa acgctcatct tatcttggaa gaagctaatt tatctcacca agaaccaatt
     3121 gccttaactt tccctcattt acttccttta tctgcccata gtcaagaagc ggttagagat
     3181 ttagctcaaa attatgaata tttcctgaaa gatcaagctt taacccctga atttgttcag
     3241 aatctttgct atagtgctag tataagacgg actcatcatg ctcatcgtca ggcggttgtg
     3301 gttcattctc ctgaagaatt attgaagggt ttaaaagagt tagaaacgat tgatttatcg
     3361 actcaatcta agccttcaaa acgtaaaaca aacattgctt ttgtcttttc tggccaagga
     3421 cctcaatggt gggcaatggg acgggaatta ttagcaacag aacccgtttt tcgctctgtt
     3481 attaaacaat gtgatacttt gattcaaaag tatgctaact ggtcattatt agcggaattt
     3541 aatgcgtctg aagctcaatc tcgtttacaa gaaacagaag tttctcaacc tgctttattt
     3601 gctttacaag ttggattagc taaagtatgg caatcttggg ggattaatcc taaatctgtg
     3661 gttggtcaca gcttgggaga agttgcagca gcccattttg cgggaattct aactcttgag
     3721 gaagccattc atttgatttg tcagcgcgga caattgatgc aacaagcaac aggaaatgga
     3781 aaaatgcttg cgattgaatt acctgttaat gaggtagaaa atttaatggc tgcttgggaa
     3841 aataaattag aaattgctgc cattaatagt ccctattcaa cggttgtatc tggggagtct
     3901 caatcgatcg atcaattaat tgctgaattg tcccaaaacc atcctcatat tttctacaaa
     3961 gaactccctg ttaattatgc ttttcatagt caacaaatga ctacttttgc ggataattta
     4021 gttaaaaaat taggagagct tcagcctcaa aaaagcacca taccaatttt ctcaaccgta
     4081 acaggtgatc aacaagaggg tacattattt aatgctgctt actggggaca aaatatgcgt
     4141 cagacggtac gttttaaccc tgcgattgaa gcaatgatta aatctcgtca tactatcttt
     4201 gttgaaatca gcccccatcc tgttttattg ggatatatta aaagtacctt acgagaacaa
     4261 gatactgagg gatttgtttt accctctcta agacgagaac attctgaacg gggaacgcta
     4321 ttaaattctt taggaaagct ctacacttgg ggacattcga ttaattggga aaaattatat
     4381 cccgaaaatt gtcagtttgt taagttaccg ctttatcctt ggcaacatga atcttattgg
     4441 gtaagtgatg ctaaacctca atttaagtct gtttcgtctg cttctagttt acttaattta
     4501 ttagttgaag gcaaaactga acaactaacg gaacagttaa atcaaagtga tcaattatca
     4561 cctgaagtca agcagttttt accgcaatta ttacagttat tggtgggaga agatacaaca
     4621 atagcaggcc agatgcctat cctacaggat gtgagtaaaa actgttacaa agtggaatgg
     4681 caactcagtc ctttaaactt aaaaaataag ccttctcaag gagaacggtg gttaattttt
     4741 aatgataatc aagtagtcgg taaagcctta gcaacaaccc taaatgatgc ttatgttttg
     4801 gtgtcttctg gtcaaactta tcagaagttg gtgtcaggtc attatcaaat taatcctaat
     4861 aatgttaagg attttcaacg gttgttacaa gatctaactg aaccaatcac caaagtggtc
     4921 tatttatggg ggttagacag cgatattaac tcccaaccct ctcaaactcg ttcttatgcc
     4981 agtttattgt atctaacaca agctttagct caatttaaaa ctaaagaacc ccctaaactt
     5041 tgggtcataa cacaacaagc acaaccggtg aatgatgctg ttaaaccgct taaaatagcg
     5101 caaacgtcct tatggggaat gggtcaagtc attgcccttg aatatcctaa tttatgggga
     5161 ggattgattg atttagaaga aaaacaacca tcgtctcaag caattattgc tgaaataaca
     5221 gaaaatctag gagaagatcg catcgctttt cgggatcatc aacgatatgt tgcccgttta
     5281 gtacctaata aagcaataaa aagctcaaac atcaatttta agaagacaga agccagttat
     5341 ctcattactg gtggcttagg ctctttagga ttaagtttag cagattggtt aattgaaaaa
     5401 ggtgcaaatc atttaatctt aaccagtcgg cgagccttag ctgaccattc aacggataaa
     5461 caggtaaaaa tcaaagcttt agaggataaa ggggctacta ttcaagtaat tgccgctgat
     5521 gtcagtgatc atcaacaaac ccgtcaactt tttcaccaaa ttcaagaaaa ttgtcctccc
     5581 ttacagggta ttattcacgc agcaggggtt ttgagcgatc gcaccattga caagatggat
     5641 ttccattgtt ttgagagcgt atttaatcct aaagcagcag gagcgtggaa tttacaccaa
     5701 ctttctcaag atttatcctt agatttcttt gtttgtttct cttccatgtc tgctttaatc
     5761 ggatcacgag gtcaaattca ctatgctgct gccaaccatt tcttagatgg tttaatgcac
     5821 taccgtcgag agtctggact cacagggtta agcattaact ggggaccttg ggctcaaggg
     5881 ggaatggcca cgcaaggcta tgaagaaggc ttaaaacgcc tgggaatcaa tccattacaa
     5941 cctaatttag ccctagatac tttagatgct ctaatcaatg gtaatgttac tcaaacaatg
     6001 gtagcagaga ttgattggtc taagtttaaa acgattgttg cagcaaaagg acgggtggct
     6061 ttcttagaag cgttattcaa gcaagatcag gataattttg tgcaaacggt cgagaatttc
     6121 cctcaaacca tccaaaaaaa acctcctcac cgacgagtca ccctattaac cactcgttta
     6181 cagcaagaag tagcgcaagt cttaggaatt cacggagata ctttaccaga tactgataaa
     6241 gggttctttg agatgggaat ggattcttta atgtcggtag aactgaaaca tcgtctagaa
     6301 ggcttatttt ctgtctcttt accttctacc tttgcttttg agtatcccac tattggtgat
     6361 gtggtgcggt attttgtcca agaagtattt gcttggcaag ataattcaga aaattctcag
     6421 atttcttcgg aaaccgagtc aacggacgtt gtagtactcc accaagccct tgctgaattg
     6481 gagtcgctgt cagaagtaga aacagaagcc ctaatggagc gagaattggc ggaattagaa
     6541 gcattacttt aacagttatc agttatcagt taagtaggtg ggtggaatta aatataaaat
     6601 gaacgtaggt tgggttgaag catgaaaccc aacgcccgca tgggttacgc taccgctaac
     6661 ccatcctac
//
