LOCUS       c00307_3300005..        9885 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300005838.a:Ga0008649_10003955.
ACCESSION   c00307_3300005..
VERSION     c00307_3300005..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 21:55:46
            Original ID  :: 3300005838.a:Ga0008649_10003955
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 9885
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..9885
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1038:7785]"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1039..7785
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
     cand_cluster    1..9885
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(HMGL-like and AMP-binding)"
                     /kind="single"
                     /product="betalactone"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..9885
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="betalactone"
                     /region_number="1"
                     /rules="(HMGL-like and AMP-binding)"
                     /tool="antismash"
     CDS             2..787
                     /locus_tag="ctg307_1"
                     /transl_table=11
                     /translation="PKGVYILPNLFTTASLFAAFYAIVQATVGNFENAAVAIIVAAILD
                     TLDGRVARLTNTVSDFGKEYDSLVDLVSFGLAPALILFEWGLQALGKSGWLVAFLYVAT
                     TALRLARFNTMDSPSKRYFQGLPCPAAAVLVAASIWAANTYMLVDPVFRGIAMVVMAAL
                     SFAMVTSLPYRSFKDLDLKHRVPFIFVLGLVLVFVLISFDPPLVVFIIFLAYALSGPVE
                     WALLRKKGINVFKPVTDEVENTSTVNDPSSDSAGPDGRD"
     CDS             1039..2391
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271:2-isopropylmalate synthase (Score: 414; E-value:
                     1.4e-125)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg307_2"
                     /sec_met_domain="HMGL-like (E-value: 6.6e-101, bitscore:
                     327.0, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDHLIIFDTTLRDGEQSPGASMTAQEKIRIARQLEKLRVDVIEA
                     GFPAASVGDFEAVEMVSAEVADSRICGLARANPSDVARAGEAIRKANAGRIHTFIATSP
                     IHMKAKLRMSPDEVLERAVSAVTQARNLVDDVEFSAEDAGRSDEDFLCRIFEAVIAAGA
                     RTINVPDTVGYTMPNQFGEMFARLLDRIPNADQAIFSVHCHNDLGVAVANSLAAVQSGA
                     RQVECTINGLGERAGNASLEEIVMAVRTRQDVFTCDTRLDSTQILTASRLVSSITGFPV
                     QPNKAIVGANAFAHEAGIHQDGVLKQRDTYEIMRAEDVGWAANQIVLGKHSGRNAFRER
                     MLALNIEFENDADLSEAFQRFKELADKKHEIFDDDLQVLAGEGDFGSGVESLKYVSLKI
                     FSETGAIPTADLMIESSGKNLHAHATGDGLVDAAFKAVEMIVPGDRILLLY"
     CDS             2392..2586
                     /locus_tag="ctg307_3"
                     /transl_table=11
                     /translation="VNAITAGSDSQGEVSVRLQEGDRVVNGQGADTDIVVASVKAYVNG
                     LNKLQSGQKRTNPQSGATV"
     CDS             2599..3300
                     /locus_tag="ctg307_4"
                     /transl_table=11
                     /translation="MDTRSRYLQEMGITQWVSRDAGFHSVPGIGVAQDLNTDESDLIQN
                     DQLMADLLTQVETCRQCGLHRTRYTTVFGVGPIPANLMIVGEAPSAEDDRQGIPFVGRV
                     GQLLASMLFSIGFKLEDVYIANALKCRPPDDRDPLAEELAHCNPFLLQQIERIQPKVIL
                     ALGKVAVQSLLETNESPGQLRNSGQVRAVAGVPVIATYHPAYLLQSPAAKPESWKDLYR
                     ARQLLINGSSA"
     CDS             3284..3757
                     /locus_tag="ctg307_5"
                     /transl_table=11
                     /translation="MARRPEEFTRAFSPERMMLSDISEVVALEQSVSPTPWSKTIFTDC
                     LKAGYECWVLRSPEVFGYLILASAAQESHLLNIAIHPDSQGRGFGSSFLEFAISLAAKE
                     GADRLFLEVRPSNSSARALYQKKDFRFLGRRPNYYGRPAKEDALVLSLEFKPD"
     CDS             3803..4600
                     /locus_tag="ctg307_6"
                     /transl_table=11
                     /translation="MTIEAHEGPPFFTRPDYQTDIPTSFAENALGRELARVTQELVKDS
                     LPEGYYEVGVQVGLSSVDLLSGVDQAIFVKSSVDCQDRTECVVVGQPGELPFSRHGINL
                     LVLAYLLEYTPEPHSVLREAFETLAPEGYLVICGFNKWSLWGLRRFFYERWRQRATLGK
                     LMSVGRIQDWIQLLDLDLVSAAIAFYRPLSSSNSVLKKLCFLEAFGDRWWPSTGGSYVV
                     VAKKKSLAKIGISEYRSHHKKSSPTPVAAMTSRHCRAENKKYI"
     CDS             4597..5043
                     /locus_tag="ctg307_7"
                     /transl_table=11
                     /translation="MSDYKTIQIFTDGACRGNPGPGGWGVLILAESGAQEFYGAEEQTT
                     NNRMELTAAIQGLGAVESGASVAIYTDSQYVKNGLESWIKAWKANGWRTSAKKPVKNQD
                     LWRALDSAAQRLAVSWHWVKGHSGHPQNERADALANLAIDEMIS"
     CDS             5048..5731
                     /locus_tag="ctg307_8"
                     /transl_table=11
                     /translation="MDLIVLDTETTGLEVGEGHRVIEVGCVCLRQRKHTDHKFHRYLNP
                     GRSIDPGAQEVHGISSEFLSDKPVFAEIADSFLEFIKGNELVIHNASFDIGFLNRELEI
                     LGLDQKIEDICRVTDSLRLAREMHPGQRNSLDALCRRYSVDNSGRELHGALLDAEILSD
                     VYLAMTGGQTLLSLNDHREVANKASLASTKYKNRKDTFPIVRASADENEAHQKWIDLLG
                     NKSLW"
     CDS             5902..7785
                     /NRPS_PKS="Domain: AMP-binding (63-502). E-value: 1.1e-99.
                     Score: 325.5. Matches aSDomain:
                     nrpspksdomains_ctg307_9_AMP-binding.1"
                     /NRPS_PKS="type: NRPS-like protein"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     314.3; E-value: 2e-95)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg307_9"
                     /sec_met_domain="AMP-binding (E-value: 1.8e-114, bitscore:
                     372.2, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNADQYEVMYRQSIDDPDSFWAAQAEKFVTWFSPWKTVSSWDYYK
                     GDIRWFEGAKVNAAYNCVDRHLETRGDQIAIIWEGDDPSEDRKISYHELHEEVCRFSNV
                     LKSRGVTKGDRVSIYMPMIPEAAVAMLACARIGAVHSVVFGGFSPEALRDRILDSDCQV
                     VITADEGPRGGKPVPLKANVEKALEGCANVHTTVIVRRTGNDVPSGGDRDVWYQEAIAS
                     ASAECPAEPMDAEDPLFILYTSGSTGKPKGVLHTTGGYQLYAAMTHHYVFDYHPGDIYW
                     CTADVGWITGHSYILYGPLANGATTLMFEGVPTYPDASRFWQVVDKHQVNIFYTAPTAI
                     RALMSQGDGPVASTSRESLRLLGTVGEPINPEAWEWYFKTVGEQRCPIVDTWWQTETGG
                     IMITPLPGATDLKPGSATRPFFGVEPALLDADGNELEGPNSGNLVLTRSWPGQMRTVYG
                     DHERFIQTYFSTYPGFYMTGDGARRDEDGYWWITGRVDDVINVSGHRMGTAEVESALVL
                     HAQVAEAAVVGYPHDIKGQGIYAYVTLMAGIEPSDELRVELIALVRSEIGPIASPDLIQ
                     WAPGLPKTRSGKIMRRILRKIAANELDNLGDISTLAEPAVVDQLIENRAVL"
     aSDomain        6091..7407
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg307_9_AMP-binding.1"
                     /evalue="1.10E-99"
                     /label="ctg307_9_AMP-binding.1"
                     /locus_tag="ctg307_9"
                     /protein_end="502"
                     /protein_start="63"
                     /score="325.5"
                     /specificity="consensus: X"
                     /tool="antismash"
                     /translation="DRHLETRGDQIAIIWEGDDPSEDRKISYHELHEEVCRFSNVLKSR
                     GVTKGDRVSIYMPMIPEAAVAMLACARIGAVHSVVFGGFSPEALRDRILDSDCQVVITA
                     DEGPRGGKPVPLKANVEKALEGCANVHTTVIVRRTGNDVPSGGDRDVWYQEAIASASAE
                     CPAEPMDAEDPLFILYTSGSTGKPKGVLHTTGGYQLYAAMTHHYVFDYHPGDIYWCTAD
                     VGWITGHSYILYGPLANGATTLMFEGVPTYPDASRFWQVVDKHQVNIFYTAPTAIRALM
                     SQGDGPVASTSRESLRLLGTVGEPINPEAWEWYFKTVGEQRCPIVDTWWQTETGGIMIT
                     PLPGATDLKPGSATRPFFGVEPALLDADGNELEGPNSGNLVLTRSWPGQMRTVYGDHER
                     FIQTYFSTYPGFYMTGDGARRDEDGYWWITGRVDDVINVSG"
     aSModule        6091..7407
                     /domains="nrpspksdomains_ctg307_9_AMP-binding.1"
                     /incomplete
                     /locus_tags="ctg307_9"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       6616..6669
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg307_9_0001"
                     /evalue="8.10E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg307_9"
                     /protein_end="256"
                     /protein_start="238"
                     /score="24.6"
                     /tool="antismash"
                     /translation="FILYTSGSTGKPKGVLHTT"
     CDS_motif       7375..7437
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg307_9_0002"
                     /evalue="4.00E-04"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg307_9"
                     /protein_end="512"
                     /protein_start="491"
                     /score="13.2"
                     /tool="antismash"
                     /translation="TGRVDDVINVSGHRMGTAEVES"
     CDS             7909..8397
                     /locus_tag="ctg307_10"
                     /transl_table=11
                     /translation="MRHYEVVFLVHPDQSEQVPAMVDKYRSVIEGSGGVVHRLEDWGRR
                     HLAYNIDKVHKAHYVLMNIECDQPTLDEISSMFKFSDAVLRNLVMRRDSAVTAASPLLD
                     ASDDGDEPEVSAPAAESTPVATTHEAATEAPVATTHETATEAPVEPTQSEDSEGESKQ"
     CDS             8403..8618
                     /locus_tag="ctg307_11"
                     /transl_table=11
                     /translation="MNKRRKFCRFTALGVEEIDYKDLDTLNAYITETGKIMPSRNTGTK
                     ARYQRQLATAIKRARFLALLPYTDHH"
     CDS             8629..9132
                     /locus_tag="ctg307_12"
                     /transl_table=11
                     /translation="MDLILLERIQNLGELGDIVSVKSGYGRNFLIPQGKAVPASSDAKE
                     KVEARRRELAQLDSERLDAAKAKATLLPDRLTVKRLAGEEGKLFGSVTPGDIAELLQAA
                     EISIERAEVSMPDGPLKTLGEHSVMVLLHPEVSASLAVIVEAENQDGVTESDGSLEEAS
                     TPSE"
     CDS             9274..9885
                     /locus_tag="ctg307_13"
                     /transl_table=11
                     /translation="MAQQFFRPSEVVSSSRLPPQAPEAEQSVLGGLLVDTRRWDEVADL
                     VKSDDFYLRAHKEIFLAVKTLQEGGHPVDVVTTSEWLKNKGTLEQSGGLAYLGELANRT
                     PGTTNVTAYARIVRERSVLRALLDAAAAISDKAYQPEGLDTEALIDFAEKAVFSISDSD
                     RRSLAGFQDIQGLLTQAVDRIEELFQSGAGITGVSTGFKDL"
ORIGIN
        1 tccaaaaggg gtttacatcc ttcccaatct ttttacaacc gcaagtcttt ttgcggcgtt
       61 ctatgccatc gtccaggcaa cggtcggaaa tttcgaaaat gcagccgtgg cgataattgt
      121 cgccgcgatc cttgataccc ttgatggtag ggtcgcccgt ttgacaaata ccgtgagcga
      181 ttttggaaaa gagtatgact cgcttgttga tcttgtgtcg tttgggctcg cacctgcgct
      241 tattcttttt gaatggggtt tgcaggcgct tgggaagagc ggctggctgg tcgccttttt
      301 atatgttgcg acgacggcgt tacgcctggc ccgctttaat acaatggact cacccagcaa
      361 gcgttacttc caaggcctcc cttgtcctgc agctgccgtc ttggtcgcag cgtcaatttg
      421 ggccgcaaat acctatatgc tcgttgaccc ggtgtttcgc ggcattgcga tggtcgtgat
      481 ggccgctctt tcgtttgcga tggtgacaag ccttccgtat cgaagcttta aagatctaga
      541 tctcaagcac cgcgtgccgt tcatctttgt tttggggctt gtccttgtat tcgtgttgat
      601 ctcctttgat cccccgctcg ttgtattcat catttttctg gcctacgcgt tgtcgggccc
      661 ggtggaatgg gcgttgcttc gaaaaaaagg aataaatgta ttcaaaccgg taactgacga
      721 ggttgaaaac acctcaacag tcaatgatcc ttcttcggat agtgcggggc ccgacgggcg
      781 ggactagatt gaagtggttt tgctggaaag cgacgataac ggtatactgg ggtgatgatc
      841 tcgcgtaatc aaatggcttt ccggacgtca aatttggatg caatcccgtc gcggcttctc
      901 gtgctggcta tcctggcgct actgcgcctg ccggcgctat ctctttccta aaaaataact
      961 tctcaaaaaa atatggcggc tgattcaaat tcgaatctgt tgctttagct atagttgttg
     1021 ctcattaggg gataaataat gtctgatcat ttaataattt ttgatacaac gcttcgcgac
     1081 ggcgagcaga gtcctggagc ctccatgact gctcaggaaa aaattcgtat tgctcgtcaa
     1141 ctcgaaaaac ttcgcgttga tgtaattgag gcgggttttc cagcggctag cgtaggtgat
     1201 tttgaagcgg tcgagatggt gtccgctgag gtcgctgata gccgaatttg tggccttgca
     1261 agagcgaatc catctgatgt ggcgcgggcc ggggaagcaa ttaggaaagc gaatgccgga
     1321 agaatccaca cctttattgc gacttcaccg attcatatga aggcaaaact ccgtatgagt
     1381 ccagatgaag tgcttgagag ggcggtttct gctgtgacgc aggctcgcaa tctcgttgac
     1441 gatgttgagt tctcagcgga ggatgcaggg cgatcggacg aagattttct gtgtcggata
     1501 tttgaggctg tgatcgcggc tggcgcgcgt acgatcaatg ttccggatac ggtgggttac
     1561 acgatgccca atcaatttgg cgaaatgttt gcgcgattac tagaccgaat acctaacgcc
     1621 gatcaggcca ttttttcagt tcactgtcat aacgacctcg gtgtcgcagt tgcgaattca
     1681 ttggctgcgg tccaaagcgg tgcgcgccag gtggagtgca cgatcaacgg actgggcgag
     1741 cgcgcgggaa acgcgtcact tgaggaaatc gtcatggcgg tcaggactcg tcaggatgtc
     1801 tttacatgcg acacccgtct tgattcaacg caaattttga cagcaagtcg cctggtctcc
     1861 agtattaccg ggtttcctgt gcaaccgaac aaagcgattg tgggcgcaaa cgctttcgcc
     1921 catgaggctg gaattcatca ggatggcgtt ctgaagcagc gcgacaccta tgagatcatg
     1981 cgcgcggagg atgtgggttg ggcggcgaac caaattgtgt tgggcaagca ttcgggacga
     2041 aatgcttttc gggagcggat gttagctcta aatattgagt tcgaaaatga tgctgatttg
     2101 agtgaggcgt ttcagcgatt taaagagctg gcggacaaaa agcatgaaat ttttgacgac
     2161 gaccttcaag tgcttgcggg agaaggcgat tttgggagcg gggttgaatc acttaagtat
     2221 gtcagtttaa aaatattttc agaaacgggt gcgataccaa ctgccgatct catgattgaa
     2281 tcttccggta aaaacctgca cgcccatgcg acaggtgatg gactggtgga tgctgcattt
     2341 aaagcggtcg aaatgattgt tcccggtgac cgaattcttc ttttatattg agtgaatgcc
     2401 atcaccgcgg gttctgattc ccagggcgag gtaagcgttc gactacaaga gggggatcgg
     2461 gttgttaatg gtcagggagc agacacggat attgtcgtcg cctcggtgaa ggcgtatgta
     2521 aacggcctta acaagcttca gagcgggcaa aaaagaacga atccgcaaag tggcgcgacg
     2581 gtgtaggtaa ataatcagat ggatacccga agccgctatc tccaggaaat ggggattacg
     2641 caatgggtca gtcgggatgc tggttttcat tctgtgcccg ggatcggtgt tgcacaggat
     2701 ttgaacaccg atgagagcga cttaatccag aatgatcagc ttatggctga tttgttaacg
     2761 caagttgaaa cctgtcggca gtgtggactg catcgcacaa ggtatacgac tgtttttggt
     2821 gtaggcccaa taccggccaa tctgatgatt gttggagaag cgccgagtgc tgaggatgat
     2881 cgacaaggaa ttccatttgt cgggcgggtc ggtcagttgc ttgcctcgat gctctttagc
     2941 atcggcttca agcttgaaga tgtttacatt gcaaatgcgc taaagtgtcg tccaccggac
     3001 gatcgggacc cgttagccga agagttagcc cattgcaatc cattcttgct ccaacagatt
     3061 gagcgaattc aaccgaaagt tattttggca ctgggtaagg ttgcagtgca gtcactctta
     3121 gagaccaacg agtcacctgg tcaattgcgc aacagtggtc aggtgcgagc agttgcggga
     3181 gtgccagtga ttgcgactta ccatccggcg tatcttctgc aatcaccggc cgcgaaacca
     3241 gaaagctgga aagatcttta tcgcgcacga cagcttttaa taaatggctc gtcggcctga
     3301 ggagttcacc cgggcttttt cacccgaacg gatgatgttg tcggacatct cggaggttgt
     3361 ggcgttagag cagagtgttt caccgacacc ttggagcaaa acaattttca ccgactgctt
     3421 gaaagcggga tatgaatgct gggttcttcg atctcctgaa gtgtttggat atttgatttt
     3481 ggcctcagcg gcccaggaat cgcatctact caatatcgcc attcatccag attctcaagg
     3541 cagaggattt gggagttctt ttttggaatt tgctatttct ttggcggcaa aggaaggggc
     3601 agaccgattg tttcttgagg ttcgtcccag caacagtagc gccagagcgc tttatcagaa
     3661 aaaagacttc cgttttctgg gaaggcgacc caattattat ggccgacccg cgaaagaaga
     3721 cgctctggta ctttcacttg aattcaagcc ggactaaact aaattttcct ccaatgaaaa
     3781 attcagattg aacgataaag tgatgactat tgaggctcat gaagggccac ctttttttac
     3841 gaggcctgac taccaaactg atattccaac aagttttgca gagaatgcgc tcgggcggga
     3901 gctcgcccgc gtgacccaag agttagttaa agattctcta cctgaaggct actatgaggt
     3961 tggggttcag gtgggtctgt catcggttga tctgttatca ggcgttgatc aggcgatttt
     4021 tgtaaagtca agcgtggact gccaggatag aaccgaatgc gttgtcgtcg gacaaccggg
     4081 cgagctacct tttagccgtc atggcattaa cctgttggtg ctcgcttatc ttctcgaata
     4141 tacgccggag ccgcactctg tgcttaggga ggcgttcgag acgttagctc cggagggtta
     4201 tctggtaatc tgcgggttta ataagtggag cttgtggggc ttgcggcgat ttttttacga
     4261 gcgctggcgg cagcgagcga cgcttggcaa gctaatgtct gtgggacgga ttcaggattg
     4321 gattcaactc ttggaccttg acttggtttc cgctgcaata gcgttttatc gccccctttc
     4381 aagctcgaac tcggtgctca aaaaactatg ttttctcgag gcgttcggcg accgttggtg
     4441 gccatcgaca ggcggcagtt atgtggtggt cgcgaaaaaa aaatcgctcg caaaaatcgg
     4501 gatatcagaa tatcgtagcc accataaaaa atcgagcccg acgccggttg cggccatgac
     4561 ctcgcgacat tgcagagctg aaaataagaa atacatatga gcgattacaa gactattcag
     4621 atcttcaccg acggcgcctg tcgtggtaat cccggaccgg gcgggtgggg cgtgctcata
     4681 ttggccgagt ctggggctca agagttttac ggagccgagg aacaaacaac taataaccgg
     4741 atggaactca ccgcagcgat tcaggggctt ggtgcggtag agtcgggagc gtcggtggca
     4801 atctacacgg attctcaata tgtcaaaaat ggtttggaaa gttggattaa ggcatggaag
     4861 gcgaacggtt ggcgaacgtc ggccaagaag cctgtaaaga accaagatct atggcgggcg
     4921 ttagattcag cggctcaacg tcttgctgta agttggcatt gggttaaagg tcatagcgga
     4981 catccacaaa atgagcgcgc agatgcatta gcaaatctgg cgatcgacga gatgatttca
     5041 taattagatg gatttaattg ttctagatac cgaaacgacg ggccttgagg tcggtgaagg
     5101 tcatcgagtg atcgaggtgg gatgtgtttg tcttaggcaa cggaagcata cggatcataa
     5161 atttcaccgt tatctgaatc cgggaaggag tattgacccg ggcgctcaag aagtgcacgg
     5221 tatttcatct gaatttttat cagataagcc ggttttcgcg gaaatagcgg atagtttttt
     5281 agagtttata aaaggaaatg agctcgttat ccataacgcg tcgttcgata tcggatttct
     5341 taatcgcgag ttggagattt taggattgga tcagaaaatt gaagatatct gtcgcgtcac
     5401 cgactctctc aggctggcgc gcgagatgca tccgggacag agaaacagtt tggatgcgtt
     5461 atgccgtaga tatagcgttg acaacagtgg tcgcgagctt catggagcac tgttggatgc
     5521 cgagattctt tctgatgtct atctcgcaat gacgggtgga cagacgctac tctccctcaa
     5581 tgatcatcgt gaagtcgcaa ataaagccag tctcgcctcg acgaaatata aaaacaggaa
     5641 agacacgttt ccgattgttc gcgcctctgc tgatgaaaat gaagcgcatc agaaatggat
     5701 tgacttgctc ggcaataaaa gtctttggta ggtgatcgaa gttatactgg attgccagtt
     5761 aggggtgatc aggtgtgcgg gcggatgctt ttggttcaac tgctagcgta aataaagacg
     5821 ctcgtagatt tatgtgagga aaatagagtg ggtgaagaaa ctgtttataa agtaataccg
     5881 aaattttcgg atcgttcaca tatgaatgcc gatcaatacg aggtcatgta ccgacaatcc
     5941 atcgacgatc cagattcgtt ctgggctgct caggctgaaa aattcgttac ttggttttcc
     6001 ccctggaaga ctgttagctc ttgggattat tacaagggtg atattcgctg gtttgaaggc
     6061 gcaaaagtca atgcggctta taactgtgtt gaccgccatc tcgagacccg aggcgatcaa
     6121 attgcaatca tttgggaggg cgatgatccc tcggaagatc gaaaaataag ttaccacgag
     6181 ctgcatgagg aggtttgtcg attctcgaat gtcctcaaaa gtcgtggggt gaccaagggt
     6241 gatcgggtat caatttatat gccgatgatt ccagaagctg ctgtcgcgat gttggcgtgc
     6301 gctcgaatcg gtgcggttca ttcagtcgtg ttcgggggct tttcgccgga agcgctgaga
     6361 gaccgtatcc tagattcaga ctgtcaagtg gtgattacag ctgatgaggg acctcgcggt
     6421 gggaaaccag ttccgttaaa ggcaaatgtg gaaaaagcgc tcgaaggatg cgctaatgtg
     6481 cataccacgg tgattgttcg tcgaacaggt aatgatgtgc cttcaggcgg tgatcgggac
     6541 gtttggtatc aggaagcgat agcgtctgca tcagcagagt gtcccgctga acccatggac
     6601 gcggaagacc ccctttttat cctgtatacc tcaggttcga cggggaaacc aaaaggggtc
     6661 ttgcatacca ctggagggta tcaactttac gcggcaatga ctcaccacta tgtatttgat
     6721 tatcaccctg gcgatattta ttggtgtacc gcggacgttg gttggattac aggacacagt
     6781 tatatcttgt atggaccgct ggcaaatggg gcgacaacgc tcatgttcga gggcgttccg
     6841 acttaccccg atgcttcgcg attctggcaa gttgtcgata agcatcaggt taatattttt
     6901 tacaccgcgc cgacggctat tcgggcattg atgagccaag gggatggacc ggtggcgtca
     6961 acctctagag agagtctccg gttgctgggt acagtagggg agccgatcaa tccagaagca
     7021 tgggaatggt actttaaaac cgtgggtgag cagcgctgtc caattgtcga cacctggtgg
     7081 caaaccgaaa ccggtggcat catgatcacg cctctgccgg gcgcaaccga tttgaagcca
     7141 ggatcggcaa ctcgtccatt ttttggagtc gagcctgcat tgctcgatgc agacgggaat
     7201 gagctggaag ggcccaactc gggcaactta gtgcttaccc gttcgtggcc gggtcaaatg
     7261 cgaacggtat acggggatca cgaacgattt attcagactt atttttcaac gtaccccgga
     7321 ttttatatga cgggtgatgg cgcaaggcga gatgaagacg gatactggtg gattaccggt
     7381 cgggttgatg atgtcattaa tgtctcgggg catcgaatgg gtaccgcaga ggtcgagagt
     7441 gcattggtgc ttcatgccca agttgctgaa gcggcggtgg tcggttatcc ccatgatatt
     7501 aaggggcagg gaatctatgc ctatgtcacg ctaatggccg gaatcgagcc aagtgatgaa
     7561 ttaagagtag agttaatcgc cttggtcaga tcagaaattg gtccgattgc gagccctgat
     7621 cttattcagt gggcacccgg tctgcctaaa acccgctctg ggaagattat gcgtagaatt
     7681 ctgaggaaga tcgcggcaaa tgaattagat aatcttgggg atatatcaac gctggcggag
     7741 cccgcagtgg ttgaccagct tatcgagaat cgagcagttt tgtaaggatt gagatacatt
     7801 cttgtcgctt taccgttcaa ccgctagaat acgccccgca cggcgctaag cgcctgctcc
     7861 ttgtctcacc gtaattagac gggaggcttt aaccgaaagg agattttaat gcgacattat
     7921 gaagtcgttt ttcttgttca tccggatcag agtgagcaag tccccgccat ggtagataag
     7981 tatcgaagcg tcatcgaagg cagcggtggc gtcgttcatc ggctcgaaga ctgggggcgt
     8041 cgtcacctgg cctacaatat tgataaagtt cataaagccc actatgtgct gatgaatatc
     8101 gagtgcgatc agcctacgct tgacgaaatt agcagtatgt ttaagtttag cgatgctgtt
     8161 cttcgcaatc tggtcatgcg tcgcgattca gcggtgacag cagcatcacc tttgttagat
     8221 gcttccgatg atggcgatga gccagaagtg tctgctccag ccgcggagtc aaccccggtt
     8281 gccaccactc atgaagccgc aaccgaagcg ccggttgcca ccactcatga aaccgcaacc
     8341 gaagcgccgg ttgagcccac tcaaagtgaa gatagtgaag gagaaagcaa acaatgaatc
     8401 gtatgaataa acgcagaaaa ttttgcaggt tcaccgcgct gggcgtggag gaaattgact
     8461 ataaggattt agacacactg aatgcttata ttaccgaaac gggcaagatt atgccgagtc
     8521 gaaatactgg cacaaaagcg cgatatcagc gccagctagc gaccgcgata aaacgggcgc
     8581 gctttcttgc gcttcttccc tataccgatc atcactgaga gcgatacgat ggatttaata
     8641 ctacttgagc gcattcagaa cctcggggaa ctgggtgaca ttgtgagcgt aaagtcgggt
     8701 tacggccgaa atttccttat tcctcaaggt aaggcagttc cagcaagctc agatgcaaaa
     8761 gaaaaagttg aagcgcgtcg tcgggaactg gcgcagcttg actctgagcg gctcgacgcg
     8821 gcaaaggcta aagcaacgtt actgccggat agactcacgg tgaagcgtct cgctggagaa
     8881 gaggggaagt tgtttggctc tgttactccc ggggatatcg cagaactgct gcaagcggct
     8941 gaaatttcga ttgagcgagc tgaggtttcg atgccggacg gcccactcaa aacccttggt
     9001 gaacatagcg taatggtcct gcttcatcct gaggtaagcg cctcgcttgc agtaatagtt
     9061 gaagctgaga atcaggatgg tgtcactgaa tctgatggat cgttagaaga ggcgagcacg
     9121 ccgtcggagt gatggtcgaa agtggggtcg agttctgcca aacaccccgc tgactggccc
     9181 gttcttaaga gtaatcgtgg tgctctgtta aaggatgccc aggttgtcta gaatagatcg
     9241 cttgttagcc cctgatacgc gacctttctt gtaatggccc agcaattttt tcgccctagt
     9301 gaggttgtct cctcctctag attgccccct caggcaccag aggctgagca gtcagttctc
     9361 ggtgggctac tcgtcgatac gcggcggtgg gatgaggtcg ctgatcttgt taagagcgat
     9421 gatttctatc tgcgcgccca caaagaaatc tttctcgcgg ttaagacgct tcaggaaggt
     9481 ggtcatccgg ttgatgttgt taccacttct gaatggctga aaaataaagg aacgcttgag
     9541 cagtcaggtg ggttagccta tctgggagaa ctcgccaata ggacgccagg aacgacaaac
     9601 gttaccgcct atgcccgtat cgtcagagag cgttctgtat tgcgagcatt attggacgcc
     9661 gcggccgcaa tttcggataa ggcctatcag ccagagggac tggacaccga ggcattaatc
     9721 gacttcgctg agaaggctgt ttttagtatt tctgattcag atcgaagatc tctagcgggc
     9781 tttcaagata ttcagggcct tctgacccaa gcggttgatc gaattgaaga attgtttcaa
     9841 tcgggtgctg gtatcaccgg ggtctcaacc gggtttaagg atctg
//
