LOCUS       c00083_3300006..       12834 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300006056.a:Ga0075163_10009391.
ACCESSION   c00083_3300006..
VERSION     c00083_3300006..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 18:59:07
            Original ID  :: 3300006056.a:Ga0075163_10009391
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12834
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     aSDomain        1..1083
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg83_1_AMP-binding.1"
                     /evalue="1.00E-83"
                     /label="ctg83_1_AMP-binding.1"
                     /locus_tag="ctg83_1"
                     /protein_end="361"
                     /protein_start="0"
                     /score="272.9"
                     /specificity="consensus: X"
                     /tool="antismash"
                     /translation="VGICLERSFDMVVALLGIMKAGGAYVPIDPTYPAGRQHTLAVDAG
                     VDLVLTQGTATPDPDTFPVPVLSLDRLNAELETLSGENLDRPISADQAAYVIYTSGSTG
                     KPKGVVVSHGALSQHILAAGAAYEFVPSDRVLQFAAVSFDVASEELWTTLISGAAVVLQ
                     PCRLFDSIPAFLDFLDRRHVTVAGLPASYWHQWVDAFEQADCSVPSRVRLLIVGNEPVA
                     SSDLNRWRRQVGRNVRWLNAYGPTETIITASLYEPPLSVEEFALHTVPIGRPLPGRSMY
                     VLDRHLEPVPFDVPGEVYIGGETLGRGYLDDPERTAGLFIPDPFGGRPGARLYRTGDRA
                     LVRSDGTIEFHGRFDDQVKLRG"
     aSModule        1..2406
                     /complete
                     /domains="nrpspksdomains_ctg83_1_AMP-binding.1"
                     /domains="nrpspksdomains_ctg83_1_PCP.1"
                     /domains="nrpspksdomains_ctg83_1_Thioesterase.1"
                     /final_module
                     /locus_tags="ctg83_1"
                     /monomer_pairings="X -> X"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS             1..2472
                     /NRPS_PKS="Domain: AMP-binding (0-361). E-value: 1e-83.
                     Score: 272.9. Matches aSDomain:
                     nrpspksdomains_ctg83_1_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (471-538). E-value: 3.7e-25. Score:
                     79.7. Matches aSDomain: nrpspksdomains_ctg83_1_PCP.1"
                     /NRPS_PKS="Domain: Thioesterase (556-802). E-value:
                     1.9e-30. Score: 98.7. Matches aSDomain:
                     nrpspksdomains_ctg83_1_Thioesterase.1"
                     /NRPS_PKS="type: NRPS-like protein"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     320.5; E-value: 2.6e-97)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg83_1"
                     /sec_met_domain="AMP-binding (E-value: 5.2e-100, bitscore:
                     324.4, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.4e-16, bitscore:
                     50.4, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VGICLERSFDMVVALLGIMKAGGAYVPIDPTYPAGRQHTLAVDAG
                     VDLVLTQGTATPDPDTFPVPVLSLDRLNAELETLSGENLDRPISADQAAYVIYTSGSTG
                     KPKGVVVSHGALSQHILAAGAAYEFVPSDRVLQFAAVSFDVASEELWTTLISGAAVVLQ
                     PCRLFDSIPAFLDFLDRRHVTVAGLPASYWHQWVDAFEQADCSVPSRVRLLIVGNEPVA
                     SSDLNRWRRQVGRNVRWLNAYGPTETIITASLYEPPLSVEEFALHTVPIGRPLPGRSMY
                     VLDRHLEPVPFDVPGEVYIGGETLGRGYLDDPERTAGLFIPDPFGGRPGARLYRTGDRA
                     LVRSDGTIEFHGRFDDQVKLRGFRIEPGEIEERLRRHPDVRDGLVVPREDAEGRTRLVA
                     YVVVREDAQFDEPDLRRWLASTLPDYMLPFLILPLTELPRTPGGKVDRGALPAPDWSGV
                     SRQSYVAPATPLQRQLAVMWSEVLAVGRIGLHDNFFDLGGHSLLAVQLIARIQKVVDRP
                     LALMELFQFPTLATLAEHLEGERRDTSPEILVLRKGRNAPPLFCFDPTGTHVQAYRPLA
                     LSMADERPVYGLSLSHLFTMRWQDVSIHQLAEQQARLIRERQRQGPYHLLGWSNGGVLA
                     LAVARLLEQGGDSVAFLGLLDTQPDQAVYAAGDATPVEELMTYIRRDRRGDFESIPQHE
                     REALQQHLASLADDNRLEYAIQWARERNFLSDEEAEASIGSLKLGYALAREAARFVTVT
                     RFNPIQAPIHVWWTTSTLAKHGKGPVDWSAHTTGLVSVDTVVGDHVDAVYSIHAHQRIG
                     DKLAGIRAPSA"
     protocluster    1..12834
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[0:2472](+)"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1..2472
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
     cand_cluster    1..12834
                     /SMILES="NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /kind="single"
                     /product="NRPS-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12834
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS-like"
                     /region_number="1"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX))"
                     /tool="antismash"
     CDS_motif       46..87
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg83_1_0001"
                     /evalue="3.20E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg83_1"
                     /protein_end="29"
                     /protein_start="15"
                     /score="20.1"
                     /tool="antismash"
                     /translation="LGIMKAGGAYVPIDP"
     CDS_motif       280..339
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg83_1_0002"
                     /evalue="2.00E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg83_1"
                     /protein_end="113"
                     /protein_start="93"
                     /score="35.5"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGKPKGVVVSHG"
     CDS_motif       358..381
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg83_1_0003"
                     /evalue="4.30E+00"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg83_1"
                     /protein_end="127"
                     /protein_start="119"
                     /score="1.7"
                     /tool="antismash"
                     /translation="ILAAGAAYE"
     CDS_motif       460..483
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg83_1_0004"
                     /evalue="9.90E+01"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg83_1"
                     /protein_end="161"
                     /protein_start="153"
                     /score="-3.0"
                     /tool="antismash"
                     /translation="LISGAAVVL"
     CDS_motif       871..954
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg83_1_0005"
                     /evalue="4.90E-12"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg83_1"
                     /protein_end="318"
                     /protein_start="290"
                     /score="38.1"
                     /tool="antismash"
                     /translation="PFDVPGEVYIGGETLGRGYLDDPERTAGL"
     CDS_motif       1048..1113
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg83_1_0006"
                     /evalue="4.20E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg83_1"
                     /protein_end="371"
                     /protein_start="349"
                     /score="37.9"
                     /tool="antismash"
                     /translation="FHGRFDDQVKLRGFRIEPGEIEE"
     aSDomain        1414..1614
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg83_1_PCP.1"
                     /evalue="3.70E-25"
                     /label="ctg83_1_PCP.1"
                     /locus_tag="ctg83_1"
                     /protein_end="538"
                     /protein_start="471"
                     /score="79.7"
                     /tool="antismash"
                     /translation="RQLAVMWSEVLAVGRIGLHDNFFDLGGHSLLAVQLIARIQKVVDR
                     PLALMELFQFPTLATLAEHLEGE"
     aSDomain        1669..2406
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg83_1_Thioesterase.1"
                     /evalue="1.90E-30"
                     /label="ctg83_1_Thioesterase.1"
                     /locus_tag="ctg83_1"
                     /protein_end="802"
                     /protein_start="556"
                     /score="98.7"
                     /tool="antismash"
                     /translation="PPLFCFDPTGTHVQAYRPLALSMADERPVYGLSLSHLFTMRWQDV
                     SIHQLAEQQARLIRERQRQGPYHLLGWSNGGVLALAVARLLEQGGDSVAFLGLLDTQPD
                     QAVYAAGDATPVEELMTYIRRDRRGDFESIPQHEREALQQHLASLADDNRLEYAIQWAR
                     ERNFLSDEEAEASIGSLKLGYALAREAARFVTVTRFNPIQAPIHVWWTTSTLAKHGKGP
                     VDWSAHTTGLVSVDTVVGDHVDAVY"
     CDS_motif       1852..1926
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg83_1_0007"
                     /evalue="4.10E-12"
                     /label="NRPS-te1"
                     /locus_tag="ctg83_1"
                     /protein_end="642"
                     /protein_start="617"
                     /score="38.4"
                     /tool="antismash"
                     /translation="QRQGPYHLLGWSNGGVLALAVARLLE"
     CDS             complement(2617..5733)
                     /gene_functions="transport (smcogs)
                     SMCOG1049:AcrB/AcrD/AcrF family protein (Score: 1087.3;
                     E-value: 0)"
                     /gene_functions="resistance (resist) RND_efflux (Score:
                     1079.5; E-value: 0)"
                     /gene_kind="transport"
                     /locus_tag="ctg83_2"
                     /transl_table=11
                     /translation="MRLSALSIERPVLAAVATLLLMLFGLLSYSRLPVREYPDTTFPIV
                     SVMTVYPSADAQLVETDITSVLEDALSGVEGLRTLRSTSREGLSTIGLEFSLMRNLDAA
                     ANDVRDRVTRVQYLLPQGIEAPLVMKEDSDSDGIMWLALISDRHTELEMTDFAERQLKD
                     RLAPLPGVSSVMLDGGRRYAMRIWLDPDRLASRLLTVQDVEDALRTQNVSMPTGRIEST
                     QREFSVRMGGGLEKAAQFNQLILAYRDGYPVRLQDVGAAEIGPEDDRKLVRVNGKPAIG
                     LGIMKQSKANTLEAARAVKRTIPAMEALLPEGMQLVTAFDSSIYIERSLHEVYEAVGLS
                     VLLVVLVVFLFLRSARATLIPAVAIPGSILGTFVIMQMTGSSINTITLLGFVLAIGLVV
                     DDAIVVVENVYRRIERGLSPTQAAIEGSREIGFAVISTTLTLAAVFFPIIFLPGIVGRL
                     FAELGIAVAGSVLLSGFIALTLTPAMCARLLGKTAGTASPSRGSALDPSAWLRWLTQRY
                     RLALKVALERPAIILGGAVLSLIVSAALMWGLPSELAPLEDTGWFAVHVSAPEGSTLDY
                     TDRYARETENATARIPEMDSYYTVVARGWRPTLVNRAVTWVTLKDWSDRNRVQQEIVDD
                     VQPALSAIPGATVFALNPPPFNQEDSKTPVQLVIRGPSYEVLDKIVTQIRHDLTGNQEV
                     VNVESDLDLNKPELRVEINRDKAADLGIPIETIGRTLEVFLGGRKASLFMREGKEYPVI
                     MQTRPHQRGTRSDIDRLHVRGTQGDLIPLSNLVTLRETVAPKQLNHYEKLRAVTISAGV
                     GADSTLSRSIESLEQTIRKHLPPGATISYAGETKELKESSGNLHLTFLLALLVVYLILA
                     AQFESFRHPITVLVSVPPALAGALLALLLFRGTLNIYSEIGLMILIGLVTKNAILIVEF
                     ANRLCQEGKSPRAAIVEAAVLRLRPIVMTTLSTILAALPLALATGAGAAGRWHIGLVVI
                     NGLVLSTLLTLFLVPVVYLLFARTAPVRQSAAVPEPFSEVLPRHSPSQG"
     CDS             complement(5756..6835)
                     /gene_functions="transport (smcogs) SMCOG1029:RND family
                     efflux transporter MFP subunit (Score: 198.5; E-value:
                     2.6e-60)"
                     /gene_functions="resistance (resist) MexH (Score: 151.4;
                     E-value: 2.8e-46)"
                     /gene_kind="transport"
                     /locus_tag="ctg83_3"
                     /transl_table=11
                     /translation="MTLRRTTYLVIFTLLALSAMLAVKWTVLTPVPASEVTGTVPAGTA
                     VVLAPVTTEAIRHTIKAVGSLRANESIMIRPEIAGRIRQVWFQEGQAVEKDQLLIEMDD
                     SELQAELAQAAAQLKVSRLTYERLKRLDLDGKRYVTKQQLDEVAGALQVSQANHALYVT
                     RLAKTKIRVPFTGVTGIRRVSPGDFVGAGRDLVNLEDLDTLKIDFKVPETMLRHLAPGQ
                     SLELTTDAYPGNTFHGTVYVIDPQVDPSTRSVQVRARIPNPQLRLRPGMFAQVLLTFGQ
                     EERALLIPEEAVMPKQDKAYVYLAQDGTAQQREVTLGTRSRGFVQVLDGLTEQDTVVRV
                     GHHKLQNGDSILALSSSPH"
     CDS             complement(6919..7374)
                     /locus_tag="ctg83_4"
                     /transl_table=11
                     /translation="MLSRRHLLQSALVVTAAVAASLSWNAPSASAQQNGDKPFHALVTD
                     AKDMQTDLKNVLFYWEEKVSETSFIPHELKHLPVKRGTATVNIKFDGVKQVEVTPGADK
                     ALPTLHITLTNGKTGDFPLAIDGSFKGDSDFGQVELPVHGLKKLEFK"
     CDS             complement(7411..8421)
                     /locus_tag="ctg83_5"
                     /transl_table=11
                     /translation="MSLTAQWDSSPRQRTSLCWAFSVTTHGLFVGMAMMLLTELPPPPP
                     PTFKWDVAVVQSPPPAAEPAPPPPVESQPPPTPQPPTPKQVQPVKPQPVVRPIQPTREV
                     QPVQHIQPVQESMPVQTAQAIQEVNRTVQEPVETVVEPVQAMMRTEAAVEQVAVVEQQT
                     PAVQQTPTAAPVMRQAEPVTQVATVVSDAPAVEAAPAPVEAPQQVEQAIVQRPVETVQH
                     RIIQQRTVRGRPEAQADFGWLAQSIFSSVDPHKRYPAEAKRNRWKGRVILKLTVEQRGG
                     AIHLLELVLKESSGHAALDRHTVDMVRTVFPLQVKHHIARAAIDVDIPITYQLAN"
     CDS             complement(8418..8792)
                     /locus_tag="ctg83_6"
                     /transl_table=11
                     /translation="MGRDIDQINVIPLVDVMLVLLVIVLTTATFITTGQVPVELAKAKE
                     SGDRKDVPLVITLTAEGSLFMNDQPVPRDGLRIVLNPHPRESSVLVRADRVTVLDRFVA
                     VVDEIRGLGFQQVNLEVVRS"
     CDS             complement(8782..9207)
                     /locus_tag="ctg83_7"
                     /transl_table=11
                     /translation="MEGLKHLIDYGIIGLLIALSLWAVAVATERWFFFRRVDVKRFHSE
                     QEFEVALTKRLVVIGTVAANAPYIGLLGTVLGIMLTFHSMGTSGTMAVQSIMVGLSLAL
                     KATAVGLLVAIPCVVLNNVLRRRVTELLTQFKVQHGT"
     CDS             9537..11642
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S9"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg83_8"
                     /sec_met_domain="Peptidase_S9 (E-value: 6e-49, bitscore:
                     155.9, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGCPFSIAITVPLCRMTSTLDRTIRSTHFIALSTLLMMTVALTG
                     GCTTAERQIPDPSPVDISEESSGRIPLKAFAFLPQVRTMALSPSGTYVAFVQNTDDKTY
                     LVTTTHDGKARRMLFESDNKKYSLRWFRWVNDERLIVGVVVADVAYGLGGPFRWTQTRL
                     LAVNRDGSDLKTDLVMSSGDIRGLSREHVPQLQDRVIGKIPGDSRSVLIALDLKTPTYP
                     DVYKLDVYTGQRELIEGSTYGIRSWMADRQGVVRLGTAVEGTIVHILVKPAGQDRWQTL
                     RKYDALREPELIPLGFDEDPNVLFVRQPLDGRAAVYSLNISQPHLPAKLFASHASYDIE
                     GGLVYSVWLKQAVGVRYQADEFASIYWNPEAKELQMRLDLALPGRMNAIYSSSQDGRRH
                     IVTSSHATQPTEWYLFDEELNRLNLMVEDYPHLKPKDLIKPIPVSFKARDGIVLHGYLT
                     RPTKAQPRQPLVLLPHGGPGSRDVMDFDYWTQFLVSRGWAVLQVNFRGSRGYGDEFLQA
                     GFKRWGLEMQDDLTDAAQYAIDNSMADPNRICIVGGSYGGYAALMGTVKTPDFYRCAVS
                     FAGVSDLIGFLKEKRSYLDYELGWERQLGAWWSDRERLKATSPVNHADKIRTPLLIVHG
                     AEDRTVPVEQSRAMVDALKEAGFKHMRYVELPDGDHYLSRQEDRLTFFREMERFLATHL
                     DQAGGSE"
     CDS             11639..11806
                     /locus_tag="ctg83_9"
                     /transl_table=11
                     /translation="MNLTMYADGERSDSNCPAGLQSEAGLAFDKTFVQRPDESLVSSWS
                     YSPARRGYDP"
     CDS             complement(11813..12235)
                     /locus_tag="ctg83_10"
                     /transl_table=11
                     /translation="MIEGSIAMKGYLIQIEDATRDNQYYRRVLFTAQHSQLVLMSLKPG
                     EEIGEEVHELDQFIRFEEGEGIVVLDGENHAVSDGFAVVIPAGTRHNVVNSGKTAALKL
                     YSLYSPPEHKDGIIHKTKQEADADHDHHFDGRTSMK"
     CDS             complement(12359..12832)
                     /locus_tag="ctg83_11"
                     /transl_table=11
                     /translation="FLQVQRGKARSRGLELEGVASFDSGLDVIASFTLLDNEVRETANP
                     LEKGKRLPQTPGQFGSLWVKYTFSGGSLKGFGIGGGARYTGYTYGDEANTFRVPSYVVG
                     DAAIDYTWKHYRFALNFNNIFNQDQFGCFDRSGSFFCTFGERRTVVGSVTYRW"
ORIGIN
        1 gtcgggattt gtctggagcg ttcgttcgac atggtcgttg ccttactcgg gatcatgaag
       61 gcgggcggtg cctatgtgcc gatcgatccg acgtacccgg ccgggcggca acacactctg
      121 gcagtcgatg cgggcgtgga tctggtcctc acgcaaggga ccgccacgcc tgaccccgat
      181 acattccctg ttccggtatt gtcgctcgac cgactgaatg cagagttgga aacactgagc
      241 ggggagaacc tcgacaggcc gatttcggcg gaccaagccg cctatgtgat ctacacatcc
      301 ggctcgaccg gcaaaccgaa aggcgtcgtg gtctcccatg gagccctgtc tcagcatatc
      361 cttgctgctg gggctgccta tgagttcgtc ccgtcggacc gggtgctgca attcgcggcc
      421 gtcagctttg acgtggcctc agaagaattg tggacgacct tgatctcggg ggctgcagtg
      481 gtgctgcaac cctgtcgtct cttcgattcc atcccggcat tcctggactt tctcgatcgc
      541 cggcacgtca cggtcgcagg gttaccggcc tcttactggc accagtgggt ggacgcgttc
      601 gagcaagccg attgctccgt gccctcacgt gtgcgcctgc tgatcgtggg gaacgagccg
      661 gtggcatcat cggatctgaa tcgatggcga cgacaggtcg gcaggaatgt acggtggttg
      721 aatgcctatg gtccgacgga aacgatcatt accgcgagcc tgtatgagcc tccgctgtca
      781 gtggaagaat ttgcccttca tacggttccg atcggaaggc cgttgccggg ccggtcgatg
      841 tacgtcctcg accggcacct cgagccggtg ccgtttgacg tgcccggcga agtgtatatc
      901 gggggcgaga cgctgggccg cggctatctc gacgatccgg aacggaccgc cggcctgttc
      961 attcccgacc ccttcggggg acggcccggc gcaagactgt acaggacggg agatcgagca
     1021 ttggtcagga gcgacggcac catcgaattc catggccgtt ttgacgatca agtcaaactg
     1081 cgcgggttcc gtatcgaacc gggggagatc gaagagcggt tgcgccggca cccggatgtg
     1141 cgagacggtc tcgtcgttcc acgggaagat gccgagggac ggaccaggct tgtggcctat
     1201 gtcgtggttc gagaggacgc acagttcgac gagccggacc tccgtcgctg gctcgcctcg
     1261 accctgccgg attatatgct ccctttcctg atcctcccgc tgaccgagct gccgcggaca
     1321 ccgggtggca aggtggatcg aggggcctta cctgcgccgg actggtcggg cgtcagccgg
     1381 caatcgtatg tggctccagc aacgccgttg cagcgccagt tggccgtgat gtggagcgag
     1441 gtgctggctg tcggccggat cggcctccat gataattttt tcgatttagg cggacattcc
     1501 cttctcgccg tccagctgat cgcccgcatc cagaaagtcg tcgatcgacc gctggccttg
     1561 atggagttgt tccagtttcc cacgctggcg actttggctg agcacctcga aggggagcgt
     1621 cgtgacacct cgccggagat cctcgtgctg cgcaaaggac gcaacgcgcc gccgctgttt
     1681 tgctttgacc cgaccggcac gcatgttcag gcctaccgcc cgctcgcgct ctcgatggcg
     1741 gatgaacgtc ccgtctatgg attgtcgttg agccatctct tcaccatgcg ttggcaggat
     1801 gtctccattc accagctcgc cgaacaacag gcccggctga ttcgtgagcg tcaacggcag
     1861 ggaccttatc atctcctggg ctggtcgaac ggcggggtcc ttgccttggc ggtggcgcga
     1921 ctgctggagc agggcgggga ctcggtcgcg tttctcggtc tgttggacac gcaaccggac
     1981 caggccgtct atgcggccgg tgacgcaacg cctgtcgagg agttgatgac ctatatacgg
     2041 cgggaccgga ggggcgactt cgagtcgatc cctcagcacg aacgagaggc gctccagcag
     2101 catctggcgt cactggcgga cgacaaccgc ctggagtacg ccatccaatg ggcgagggaa
     2161 cgaaactttc tttccgatga ggaagctgag gcctcgatcg gctctttgaa gctcggttat
     2221 gccctggcga gggaggctgc acgattcgtg accgtgaccc gcttcaatcc gattcaggcg
     2281 ccgatccacg tctggtggac gacgagcacc ttggcgaaac acggcaaggg cccggtcgac
     2341 tggtcggccc atacaacggg tctcgtgtcg gtggatacgg tggtcggaga tcacgtggac
     2401 gccgtctaca gcatccacgc acaccagcgg atcggggaca agctcgccgg cattcgcgcg
     2461 ccgtcggcat aacgaacacc gacggctctg tctcgaagcg ggtttcctgc cgttcttgcg
     2521 gccattaagc cggaagactc tttgaccctc cgtcttcccg aactttcacg attttatcct
     2581 gaagacatca gtccggccct gcagtggccg tcgctgtcag ccttgtgaag gcgagtgacg
     2641 cggcaggact tccgagaatg gctcaggcac cgctgcggac tgtcggaccg gagcagtcct
     2701 ggcaaaaagg aggtagacca ccggcaccag gaagagggtg aggagcgttg agaggacgag
     2761 cccgttgatc acgaccaggc cgatgtgcca gcgcccggct gcgccggcgc ccgtcgccag
     2821 cgccaggggc agcgcggcca gaatggtgga caatgtcgtc atgacgatgg gccgcaggcg
     2881 caacacggcg gcctcgacga tggcagcgcg cggagatttg ccttcctggc acagccggtt
     2941 ggcaaattcg acaatgagga tggcgttttt ggtgacgagg ccgatcagga tcatcaaccc
     3001 gatctcacta tagatgttca aggtgccgcg gaacagcagc agcgccaaca gcgcgccggc
     3061 cagcgccggg ggaaccgaga cgaggacggt gatcgggtgg cggaagcttt cgaactgcgc
     3121 ggccaggatg aggtagacga cgagcagggc caggagaaac gtgagatgca gattgcccga
     3181 cgactccttg agctctttcg tctctcccgc ataactgatg gttgcgccgg gaggcaggtg
     3241 cttgcggatc gtctgttcga gtgattcgat ggaccggctg agcgtcgaat cggcccccac
     3301 tcccgcgctg atcgtgacgg ccctcagttt ttcgtaatgg ttcagctgtt tcggggccac
     3361 ggtttcccgc agcgtgacga gattgctcaa gggaatcaaa tccccctggg tcccacggac
     3421 gtgcagtcgg tcgatatccg atcgagtgcc gcgttgatgg ggccgcgttt gcatgatgac
     3481 gggatactct ttgccttcgc gcatgaacag ggaggccttt ctcccgccga ggaacacttc
     3541 caacgtcctg ccgatcgtct cgatcggaat gcccaggtcc gcggccttgt cgcggttgat
     3601 ctccacccgg agttccggtt tgttcaaatc caaatcgctc tcgacattga ccacctcctg
     3661 gtttccggtg aggtcatgcc ggatctgtgt cacgatcttg tccaacacct cgtacgaggg
     3721 gccgcgaata accaactgca ccggcgtttt gctgtcctcc tgattgaacg ggggcggatt
     3781 gagagcaaag accgtggcgc cggggatggc ggagagggca ggttgcacgt catcgacgat
     3841 ttcctgctgg acgcggttgc gatcggacca atccttgagc gtcacccagg tcacggcccg
     3901 gttcaccagg gtcggcctcc agcctcgcgc gaccaccgta tagtaggagt ccatttcggg
     3961 aatgcgtgcc gtggcgttct cggtttccct ggcgtaacgg tcggtgtagt cgagagtaga
     4021 gccttccggc gcactgacgt ggacggcaaa ccatccggta tcttcaagtg gtgccagttc
     4081 gctggggaga ccccacatga gggcggcgct gacgatcagt gacaggacgg ctccacctag
     4141 gatgatcgcg ggcctttcca aggcgacttt cagggcgagg cgatagcgtt gagtgagcca
     4201 gcggagccaa gccgaaggat ccagtgcgga gcctcgggac ggcgaggcgg ttcccgcagt
     4261 ctttccgagc aaccgcgcgc acatggcggg ggtgagagtg agggcgatga acccggacag
     4321 gagcaccgag ccggcgacgg cgatgcccag ttcggcaaac aggcgaccga cgataccggg
     4381 cagaaaaatg atcggaaaga agaccgccgc aagcgtcagg gttgttgaga tgaccgcaaa
     4441 cccgatttcc cggctgcctt cgatcgcggc ttgtgtcggg ctcaaccccc gttcaatgcg
     4501 gcggtagacg ttttccacca cgacgatggc gtcgtctact accagtccga tggccagcac
     4561 gaatcccaac agggtgatcg tattgatcga gctgccggtc atctgcatga tcacgaaggt
     4621 acccaggatg gagcctggaa tggcgacggc ggggatgagt gtggcgcggg cgctgcgcag
     4681 gaacaggaac actaccagca cgacgagcag cacggacagg ccgacggcct cgtacacttc
     4741 gtgcagcgac cgctcgatgt agatcgagct gtcgaacgcc gtgacgagct gcatcccttc
     4801 cggaagcaac gcctccatgg ccgggatggt gcgcttgacg gcgcgtgccg cttcgagcgt
     4861 attcgccttc gactgtttca tgatgccgag gccgatggcg ggtttgccgt tcacgcgcac
     4921 gagtttgcga tcgtcttccg ggccgatctc cgcggcaccc acgtcctgca gccggaccgg
     4981 atagccgtcc cgataggcca gaatcagttg attgaactgc gccgctttct ccaggcctcc
     5041 acccatgcgc acactgaact cccgctgggt gctttcgatc cggccggtgg gcatggagac
     5101 gttttgtgtc cggagcgcgt cttcgacgtc ctgcacggtg aggagccgcg aggcgagtcg
     5161 gtcgggatcc agccagatcc gcatcgcata ccggcggcct ccgtcgagca tgacgctgga
     5221 gacgccgggc aggggcgcga gtcgatcctt cagctggcgt tcggcaaagt ccgtcatttc
     5281 cagctcggtg tggcggtcgc tgatcagcgc cagccacatg atgccgtctg agtcgctgtc
     5341 ctccttcatc accaagggcg cttcgatgcc ctgcggaagc aggtattgaa ctctcgtcac
     5401 gcggtcgcgc acgtcgttgg ccgccgcatc caggttgcgc atcaacgaga attcgagacc
     5461 gatcgtggac agtccctcac gactggtcga gcgcaacgtc cggagccctt ccacgccgct
     5521 gagggcatcc tccagcaccg aggtgatatc cgtttccacc aattgggcat ccgcgctcgg
     5581 atacacggtc atgaccgaga caatggggaa ggtggtgtcg ggatactcgc ggaccggcaa
     5641 gcgggaatag gagagcaggc cgaagagcat cagcaggagc gtcgcaacgg cggcgaggac
     5701 gggtcgctca atggagaggg cggagagtct catggggagg tccgatgggt tgtcgttagt
     5761 gaggcgacga ggatagggcc agaatggaat cgccgttctg cagcttgtgg tggccgaccc
     5821 ggaccaccgt atcctgttcc gtgagtccgt ccagcacttg cacgaagccc ctggagcggg
     5881 tgcccagcgt gacctctcgc tgttgggcgg ttccgtcttg ggcgaggtag acgtaggcct
     5941 tgtcctgttt cggcatgacg gcctcttctg gaatcagcag cgcccgctct tcctgtccga
     6001 acgtgaggag cacttgcgcg aacatgccgg gtctgagccg cagctgtgga ttcggaattc
     6061 tcgcccgcac ctgcacggac ctcgtgctcg ggtcgacctg aggatcgatc acgtagaccg
     6121 tgccatggaa cgtgttcccc ggataggcgt ccgtggtcag ttcgagggac tgacccggcg
     6181 ccagatggcg cagcatggtt tccggcacct tgaaatcgat cttcaaggtg tcgagatctt
     6241 ccaggttcac gagatcccgg ccggcaccga cgaagtcgcc gggggagacg cgccggatgc
     6301 cggtgacgcc ggtgaagggg acccgaattt tcgtcttggc cagtctggtc acataaagcg
     6361 cgtggttggc ttgagagact tgcagcgcgc cggccacttc atcgagttgc tgtttcgtca
     6421 cgtaccgctt tccgtcgagg tcgagtcgtt tgagccgttc gtaggtgagt cggctgactt
     6481 tgagttgcgc cgcggcttga gccagttccg cctggagttc cgaatcgtcc atttcgatga
     6541 gcagctggtc tttctccacc gcctgacctt cttgaaacca gacctgacgg attcgccccg
     6601 cgatctccgg acggatcata atgctctcat tggcccgcaa ggagccgacg gctttgatcg
     6661 tgtgccggat cgcctcggtg gtgaccgggg cgagcacgac ggccgtccct gccggcacgg
     6721 ttcccgtcac ttccgaggca ggaaccggag tcagcacggt ccacttcacg gcgagcatcg
     6781 cggagagtgc gagcagcgtg aagataacga ggtaggtggt acgacggagc gtcatgagcg
     6841 gtgctgctgg tcctggctcc tgttcattcg gcctcacgcg gctcccgacg gatgatcggg
     6901 agggggcccc ggtgctgttt acttaaactc gagcttcttg agaccgtgga ccggcagctc
     6961 aacttggccg aaatccgagt cgcctttgaa gctgccgtcg atcgccagcg gaaagtcgcc
     7021 cgtcttgccg ttggtcaagg tgatgtggag cgttggcagc gccttgtccg ctccgggagt
     7081 cacctcgacc tgtttgacgc cgtcgaactt gatgttgacc gtggcggtgc cgcgtttcac
     7141 cggcaggtgc ttcaactcgt gggggatgaa cgaggtctcg ctcacctttt cttcccaata
     7201 gaacagtaca ttcttcaggt cggtttgcat gtctttcgca tcggttacga gggcgtgaaa
     7261 cggtttgtcg ccgttctgct gggcggaggc ggacggtgcg ttccaagaaa gagaggcggc
     7321 gacagcggcg gtgacaacta gggccgattg taagagatgg cggcgtgaca acatgaatcc
     7381 ctcctgttgg tcaaaatcta ggggaaataa ttaatttgcc aattgatatg taatcgggat
     7441 atcgacgtcg attgctgctc gtgcgatgtg atgcttgacc tgaagcggaa agacagtccg
     7501 caccatgtcg actgtgtgac gatccaacgc cgcgtgcccc gaactctcct ttaataccaa
     7561 ttcgagcaaa tggatcgcgc ctccgcgttg ttcgacggtg agtttcagaa tgacgcggcc
     7621 tttccaacgg ttccgtttag cctcggccgg atagcgtttg tgcgggtcga ccgaggaaaa
     7681 aatactctgc gccagccaac cgaagtcagc ctgcgcctcc ggacggcctc gcaccgttcg
     7741 ctgttgaatg atccggtgct gcacggtttc taccggccgc tgaacgatcg cctgttccac
     7801 ctgttgtgga gcctctacgg gtgcgggtgc cgcttcgacc gcgggggcgt cgctcacgac
     7861 ggtggccacc tgcgtcacgg gttcggcctg gcgcatcacc ggcgctgcgg tgggcgtttg
     7921 ctggacagcc ggagtctgtt gttccacgac ggcgacctgc tcgacggcgg cttcagtccg
     7981 catcatggct tgcaccggtt caaccacagt ctctaccggc tcctggaccg tgcggttgac
     8041 ctcttgaatg gcctgagcgg tttgcacggg catgctctcc tgaaccggct ggatatgttg
     8101 aaccggctgc acttcgcggg tcggctggat cggccggacg acgggctggg gcttcaccgg
     8161 ttggacctgt tttggcgtgg gcggttgcgg ggtaggggga ggctgcgatt ccacgggagg
     8221 gggaggcgcc ggttcggccg caggaggcgg agactgcacg accgcgacat cccacttgaa
     8281 ggtgggcgga ggcggcggag gcagttcggt gaggagcatc attgccatgc ccacgaagag
     8341 gccgtgcgtc gtcacggaga acgcccagca cagcgaagta cgttggcgcg gcgacgagtc
     8401 ccactgggct gtcaggctca tgaacgtacc acctccaagt tgacctgctg aaatccaagt
     8461 ccgcgaattt catcgacaac agccacgaat cgatccagca ccgtcacccg gtcggcgcgc
     8521 accagtacgg aagattcgcg cggatgagga ttgagcacga ttcgtagtcc gtcgcgtggc
     8581 accggctgat cgttcatgaa aagcgagccc tccgccgtca gggtgatgac aagcgggaca
     8641 tccttgcggt ctccggactc cttggccttt gccagttcga cgggcacctg gccggtggta
     8701 ataaaggtcg ccgtggtcag gacgatcacc agtaagacca acatgacgtc caccagagga
     8761 atgacattga tctggtcgat gtcacgtccc atgttgaacc ttgaactggg tgaggagttc
     8821 cgtgacgcgc cgacgaagca cgttgttgag gacgacgcag ggaatggcga cgagcagccc
     8881 gaccgccgtg gccttgaggg caagactgag cccgaccatg atcgattgga ccgccatggt
     8941 gcctgaggtg cccatgctat gaaacgtcaa catgatcccg agcacggttc cgagcagacc
     9001 gatatatggg gcgttggccg caacggtgcc gatcacgacc aatcgtttcg tgagggccac
     9061 ctcgaattcc tgctcgctgt gaaagcgttt gacatccaca cgtcgaaaga aaaaccatcg
     9121 ttccgtcgcc acggcgaccg cccaaagact cagcgcgatc aggagcccga tgatgccgta
     9181 gtcgatcaga tgcttcagtc cctccattgg aatggatcct ttctggttac tccgatcacg
     9241 ctctgccggt gcccatgtag gacagagctc cagcgcgtag cacatcgtta ctaatgacgt
     9301 atgaacgggc acgttcaaca ccttggaatg aaaataattc ttaactgatt gaaagtattg
     9361 aatgtgtgtg tctggaaatg aaatgaagtc gcctcgtcca cgagcacaat tacggcgatg
     9421 tgccctctct ccgccgcgag attcgatcgt tcaattgacc gcttttcaat ccctttctac
     9481 actgtgctct gctcttgtgc ttagttgcct tcactcaatt tgatgagggg tgtgtcatgt
     9541 ctggttgtcc gttctccatt gcgatcaccg ttcccctttg ccgcatgacg tcgacccttg
     9601 acaggacaat ccggtccaca cacttcatcg cactgtcgac gctgttgatg atgacggtcg
     9661 cgctcaccgg aggctgcacg acggctgaac ggcagattcc cgacccatcg cctgtggaca
     9721 tcagtgagga gtcgtccggc cggattccgc tcaaggcatt cgcattcctc ccccaggtcc
     9781 ggactatggc gttatccccc tccggaacgt atgtggcctt tgtccagaat accgacgaca
     9841 aaacctactt ggtcacgacg acccatgacg gaaaagctcg ccgcatgctg tttgaaagcg
     9901 acaataaaaa atactctctt cgatggtttc ggtgggtgaa tgacgagcgg ctcatcgtcg
     9961 gggtcgtagt tgcggatgta gcgtatggtt tgggagggcc gttcagatgg acacaaacac
    10021 gtctcctggc cgtcaatcgc gacgggtcgg atctcaagac agatttggtg atgtcgtccg
    10081 gcgacattcg cgggctgagt cgcgaacatg ttccgcagct tcaggacagg gtcatcggca
    10141 aaattcctgg agatagccga tccgtactca ttgcgcttga cctcaaaacc cccacctatc
    10201 ccgatgtcta caaattggac gtatatacag gtcagcgtga gttgatcgag gggagcacct
    10261 acggaattcg gagctggatg gccgatcgac agggtgtcgt acgattggga acggccgtcg
    10321 aaggaaccat cgtccacata ctggtcaaac cggcaggaca ggaccgctgg cagacgctga
    10381 gaaagtatga cgcattgcgc gagccggagc tgattccatt gggttttgac gaagatccga
    10441 atgtgctatt tgtccggcaa ccgctggatg gaagagccgc tgtgtatagc ctcaacattt
    10501 ctcaaccaca ccttccggcg aaattgttcg cctcgcacgc gtcctatgat atcgaaggtg
    10561 gtcttgtcta ttcggtctgg ctgaaacaag ccgtgggcgt tcgctatcag gcggatgaat
    10621 tcgcaagcat ctattggaat cctgaggcca aagagctgca gatgagactc gatctggccc
    10681 ttcctgggcg aatgaatgcg atctacagca gcagtcagga tggccgtaga cacatcgtga
    10741 cctccagcca tgcgactcag cccacggagt ggtatctgtt cgatgaggag ctcaatcggc
    10801 tcaatttgat ggtggaagac tatccacatc tgaaaccaaa agacctgata aaaccgatac
    10861 cggtgtcctt caaggccagg gatgggatag tcctgcatgg ctatctgact cgtccgacga
    10921 aggcacagcc gcgtcagccg ttggtcttgc tgcctcatgg tggaccgggc agcagagacg
    10981 tgatggattt cgattactgg acccagtttc tcgtgagtcg cggttgggcc gtgctgcaag
    11041 tgaattttag gggctccaga ggctatggcg acgaattctt gcaagcggga ttcaagcgct
    11101 ggggactcga aatgcaggac gatctgacgg atgcggctca gtatgcgatc gacaacagca
    11161 tggccgatcc aaaccgcatc tgtatcgtcg gcggaagtta cggtggttat gccgcgttga
    11221 tgggcaccgt caagacaccg gatttctatc gctgcgcagt gagcttcgcc ggagtatcgg
    11281 atctgatcgg cttcctcaaa gagaagcgat cctatctcga ctacgagttg ggatgggaac
    11341 ggcagttagg agcctggtgg tccgatcgcg aacggcttaa ggcaacgtct cctgtcaacc
    11401 acgccgacaa gatacgcacc ccgctcttga tcgttcacgg ggcggaggat cggactgtgc
    11461 cggttgaaca atcccgcgcg atggtcgatg ccttgaaaga agcgggtttc aagcacatgc
    11521 gttatgtcga actgccggat ggcgatcatt acctcagccg ccaagaggac cgcctcacgt
    11581 tcttccgtga gatggagcgg tttctcgcca cccatctcga tcaggcggga gggtctgaat
    11641 gaacttgacc atgtatgctg atggggagag gtccgattca aactgtccgg caggtttgca
    11701 gagcgaggca gggctggcct tcgacaagac cttcgtgcag cggcccgacg agtctctcgt
    11761 cagctcatgg agttactcgc ccgcgcgccg aggatatgac ccgtaaacag ccctatttca
    11821 ttgacgtccg accgtcaaaa tgatgatcgt gatccgcgtc ggcttcctgc ttcgttttgt
    11881 gaatgattcc atctttatgt tccggagggc tatagagact gtacaactta agtgctgccg
    11941 ttttcccgct attgacgaca ttgtgcctgg tcccggccgg gatgacgacc gcaaagccgt
    12001 cgctcaccgc gtggttctct ccgtccagga ccacgattcc ctcgccctct tcgaaacgaa
    12061 taaactgatc caactcatga acctcttctc cgatttcttc accaggcttg aggctcatca
    12121 acaccagctg ggagtgttgt gccgtaaaga gcactcgacg gtaatactga ttgtcgcgtg
    12181 tggcatcttc gatttgaatg agatagcctt tcatggcgat gctcccttcg atcatgaatc
    12241 ctctgaacaa ggggtccaag aaggacactg taccctggca tcccaaggtg gacgagtcaa
    12301 gcgtcacgta tcggcgaccg gacgaccgtc gatgaacagg tagggtctca tgctgcgttt
    12361 accatcgata ggtgacgctt cccaccacag tgcgccgttc gccgaaggtg caaaagaaac
    12421 tgccgctccg gtcgaaacag ccgaattgat cttgattgaa aatgttgttg aagttcagcg
    12481 cgaaccgata atgcttccag gtgtagtcga tggcggcgtc ccccacgaca tagctgggga
    12541 cgcgaaaggt gttggcttca tcgccgtagg tatacccggt ataccgcgct ccgccgccga
    12601 tcccgaaccc cttcaggctc ccgccggaga acgtgtattt cacccataat gacccgaatt
    12661 gcccgggtgt ctgcggcagc cgttttccct tttcgagcgg gttggcggtc tccctgactt
    12721 cgttgtccag tagggtaaac gaagcgatga cgtccagccc ggagtcgaaa cttgccaccc
    12781 cttccaactc cagacctcgc gaacgggctt ttccccgctg tacctggaga aagg
//
