LOCUS       c00109_3300008..        3044 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300008347.a:Ga0115411_1005938.
ACCESSION   c00109_3300008..
VERSION     c00109_3300008..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 08:28:39
            Original ID  :: 3300008347.a:Ga0115411_1005938
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 3044
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..3044
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2:2627](+)"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3..2627
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..3044
                     /SMILES="NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..3044
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="(cds(Condensation and (AMP-binding or A-OX)) or
                     (Condensation and AMP-binding))"
                     /tool="antismash"
     CDS             3..2627
                     /NRPS_PKS="Domain: AMP-binding (16-277). E-value: 7.7e-56.
                     Score: 181.1. Matches aSDomain:
                     nrpspksdomains_ctg109_1_AMP-binding.1"
                     /NRPS_PKS="Domain: PP-binding (395-458). E-value: 3.5e-11.
                     Score: 35.3. Matches aSDomain:
                     nrpspksdomains_ctg109_1_PP-binding.1"
                     /NRPS_PKS="Domain: Condensation_DCL (474-747). E-value:
                     1e-22. Score: 72.4. Matches aSDomain:
                     nrpspksdomains_ctg109_1_Condensation_DCL.1"
                     /NRPS_PKS="type: NRPS"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     207.1; E-value: 6.1e-63)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg109_1"
                     /sec_met_domain="Condensation (E-value: 1.3e-30, bitscore:
                     93.6, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 1.2e-65, bitscore:
                     208.7, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.4e-12, bitscore:
                     35.3, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="IPAAAGTGFRPVHTDGAEPAAVLFTSGTSGGPKCVRTTHRAMLRL
                     CGDNSLFRMEEPRTVPLAAPAAWDMFGLELWGALLSGGTCVVVSDPFLSAAALREGVAR
                     WGVNAVWLTTSLFNLLVDDDIGAFEGLSEVVIGGERVSPGHIRTFLQRHGSIRLVNGYG
                     PVESLALATSRTVEPADCERPEGVPIGVPLPGTAVHVLDGDRPCAVGEIGEICIAGDGL
                     ALEYIGDPERTTRAFPTLVLDGVPTRVYRTGDLGSWGADALLTYSGRADRQLKVRGNRV
                     EPAEVEAQIEQDADVQICRVVAQRDEAGAAVALAAFCVPRVAGDPLTGLAERLGVRLSA
                     QHLPRTVTVVPRLPLTERGKIDDRALLAHLDSGPTTPQSPAPQTATGALGGAVRDLVVE
                     CFAAILGRTDIDPAASLFELGGTSLDAGRLCARLSNSLDRPVPLSMIYSSPGIDALAAT
                     LASLTGESCNEDGDDSLSPMQVAFLTRHLADPTDTTNVCLMVWHVAGTPDLDRLRAAVS
                     AVHERHEALGSIYTLDPLPVALPLGSEPPDVQVLPAASSLVEGEATLTAALSKGLDPLT
                     GSLWRVAVLPVGSDTLVGCSVHHIAFDGASESILARDLAAAYDGHLQVPSDLPSVRRLR
                     RVEDVTVVSATLAELEGVPPIVWPRVAADVRRALGHASVRLDLDLVAAVDRRVRDGGHT
                     RFVILLAAWAHALARVIGVQDIAVGVPVSQRADPSQQDAVGCHMTMVPLRLRADALTGD
                     IDAVDQVVRTGFIRQDIPITTLLANSTDHGGRPPLFQTLFGVQDNPPPILQLDGHITRF
                     LRQPYLDLTLELHAEVWVEGEGLTLVVTHRPDAVPDETAHALLEQFPKSLAAMVNGRAS
                     VPV"
     aSDomain        51..833
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg109_1_AMP-binding.1"
                     /evalue="7.70E-56"
                     /label="ctg109_1_AMP-binding.1"
                     /locus_tag="ctg109_1"
                     /protein_end="277"
                     /protein_start="16"
                     /score="181.1"
                     /specificity="consensus: X"
                     /tool="antismash"
                     /translation="AEPAAVLFTSGTSGGPKCVRTTHRAMLRLCGDNSLFRMEEPRTVP
                     LAAPAAWDMFGLELWGALLSGGTCVVVSDPFLSAAALREGVARWGVNAVWLTTSLFNLL
                     VDDDIGAFEGLSEVVIGGERVSPGHIRTFLQRHGSIRLVNGYGPVESLALATSRTVEPA
                     DCERPEGVPIGVPLPGTAVHVLDGDRPCAVGEIGEICIAGDGLALEYIGDPERTTRAFP
                     TLVLDGVPTRVYRTGDLGSWGADALLTYSGRADRQLKVRG"
     aSModule        51..1376
                     /complete
                     /domains="nrpspksdomains_ctg109_1_AMP-binding.1"
                     /domains="nrpspksdomains_ctg109_1_PP-binding.1"
                     /locus_tags="ctg109_1"
                     /monomer_pairings="X -> X"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       60..119
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg109_1_0001"
                     /evalue="5.20E-05"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg109_1"
                     /protein_end="39"
                     /protein_start="19"
                     /score="16.1"
                     /tool="antismash"
                     /translation="AAVLFTSGTSGGPKCVRTTHR"
     CDS_motif       402..440
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg109_1_0002"
                     /evalue="5.30E+00"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg109_1"
                     /protein_end="146"
                     /protein_start="133"
                     /score="0.4"
                     /tool="antismash"
                     /translation="VVIGGERVSPGHIR"
     CDS_motif       627..713
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg109_1_0003"
                     /evalue="1.20E-11"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg109_1"
                     /protein_end="237"
                     /protein_start="208"
                     /score="36.8"
                     /tool="antismash"
                     /translation="VGEIGEICIAGDGLALEYIGDPERTTRAFP"
     CDS_motif       798..863
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg109_1_0004"
                     /evalue="3.70E-09"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg109_1"
                     /protein_end="287"
                     /protein_start="265"
                     /score="28.8"
                     /tool="antismash"
                     /translation="YSGRADRQLKVRGNRVEPAEVEA"
     aSDomain        1188..1376
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg109_1_PP-binding.1"
                     /evalue="3.50E-11"
                     /label="ctg109_1_PP-binding.1"
                     /locus_tag="ctg109_1"
                     /protein_end="458"
                     /protein_start="395"
                     /score="35.3"
                     /tool="antismash"
                     /translation="LVVECFAAILGRTDIDPAASLFELGGTSLDAGRLCARLSNSLDRP
                     VPLSMIYSSPGIDALAATL"
     misc_feature    1425..1427
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     aSDomain        1425..2243
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg109_1_Condensation_DCL.1"
                     /domain_subtype="Condensation_DCL"
                     /evalue="1.00E-22"
                     /label="ctg109_1_Condensation_DCL.1"
                     /locus_tag="ctg109_1"
                     /protein_end="747"
                     /protein_start="474"
                     /score="72.4"
                     /tool="antismash"
                     /translation="LSPMQVAFLTRHLADPTDTTNVCLMVWHVAGTPDLDRLRAAVSAV
                     HERHEALGSIYTLDPLPVALPLGSEPPDVQVLPAASSLVEGEATLTAALSKGLDPLTGS
                     LWRVAVLPVGSDTLVGCSVHHIAFDGASESILARDLAAAYDGHLQVPSDLPSVRRLRRV
                     EDVTVVSATLAELEGVPPIVWPRVAADVRRALGHASVRLDLDLVAAVDRRVRDGGHTRF
                     VILLAAWAHALARVIGVQDIAVGVPVSQRADPSQQDAVGCHMTMVPLRLRAD"
     aSModule        1425..2243
                     /domains="nrpspksdomains_ctg109_1_Condensation_DCL.1"
                     /incomplete
                     /locus_tags="ctg109_1"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       1497..1580
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg109_1_0005"
                     /evalue="2.40E-05"
                     /label="C2_LCL_024-062"
                     /locus_tag="ctg109_1"
                     /protein_end="526"
                     /protein_start="498"
                     /score="16.7"
                     /tool="antismash"
                     /translation="MVWHVAGTPDLDRLRAAVSAVHERHEALG"
     CDS_motif       1791..1856
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg109_1_0006"
                     /evalue="2.70E-08"
                     /label="C3_LCL_132-143"
                     /locus_tag="ctg109_1"
                     /protein_end="618"
                     /protein_start="596"
                     /score="26.3"
                     /tool="antismash"
                     /translation="VHHIAFDGASESILARDLAAAYD"
     CDS_motif       2145..2234
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg109_1_0007"
                     /evalue="2.90E-08"
                     /label="C5_LCL_267-296"
                     /locus_tag="ctg109_1"
                     /protein_end="744"
                     /protein_start="714"
                     /score="26.2"
                     /tool="antismash"
                     /translation="DIAVGVPVSQRADPSQQDAVGCHMTMVPLRL"
     CDS             complement(2902..3042)
                     /locus_tag="ctg109_2"
                     /transl_table=11
                     /translation="RLRKHFGSHLAEHRIGALPYTVVVLLMMLNTVRQTNLEIASRNSG
                     S"
ORIGIN
        1 acatccctgc tgccgccggc accggcttcc ggcccgtcca caccgacggc gccgagccgg
       61 cagcggtgct gttcacgtcc ggtactagcg gcgggccgaa gtgcgtgcgc acgacccacc
      121 gggccatgct gcggctctgc ggggacaaca gcctcttccg gatggaggaa cctcggacgg
      181 tcccgctggc ggcacccgcg gcatgggaca tgttcggact ggaactgtgg ggcgcgctgc
      241 tgtcgggcgg cacttgcgtc gtcgtgtcag acccctttct gtcggcggcc gccttgcgtg
      301 agggcgtcgc ccgctgggga gtgaacgctg tctggctcac caccagcctg ttcaacctgc
      361 tggtggacga cgacatcggg gccttcgagg ggctctcgga ggtggtgatc ggtggagagc
      421 gcgtctctcc gggtcacatc cgcaccttcc tccagcgaca cggaagcatc cggctggtga
      481 acgggtacgg gcccgtggag agcctcgccc tcgcaacctc gcgcacggtg gaaccggcgg
      541 actgtgagcg cccggaaggc gtcccgatcg gggttcccct gcccgggaca gcggttcacg
      601 tgttggacgg tgaccgtccg tgcgccgtcg gcgagatagg cgagatctgc atcgctggcg
      661 acggcctggc cctcgagtac ataggggacc ccgaacgcac gacgagggcg ttccccacgc
      721 tggtcctgga cggcgtcccg actcgcgtgt atcgcacggg ggatctcggg tcctggggcg
      781 cggacgcatt gttgacctac agtggccgcg ccgaccggca gctcaaagtg cgcggcaacc
      841 gcgtcgagcc cgccgaggtg gaggcgcaga tcgaacagga cgccgacgtg cagatctgcc
      901 gggtggttgc gcagcgcgac gaggcggggg ccgccgtggc gctcgctgcg ttctgcgtac
      961 cccgcgtcgc tggggacccg ctcaccgggc tcgcggagcg attgggcgtg cgcctgtccg
     1021 cgcagcacct tccgcgcacg gtcacggtcg tcccccggct tccgttgacc gagcggggca
     1081 agatcgacga ccgggcgctg ttggcgcacc ttgattccgg cccgacgacg ccccaatcgc
     1141 ccgccccgca gacagccaca ggtgccctgg ggggcgcggt gagggacttg gtggtggagt
     1201 gctttgcggc catcctgggg cggacagata ttgacccggc agcatcccta ttcgagttgg
     1261 gcggaacctc gctggatgcg ggacgcctgt gcgctcgtct cagcaacagc ctcgatcgcc
     1321 cggtcccgtt gagcatgatc tactcttcgc cggggatcga cgccttggcc gccacgttgg
     1381 cctcactcac aggcgaatcg tgcaatgagg acggggacga ctcattatcg ccgatgcagg
     1441 tcgccttcct gaccagacac cttgccgacc cgacggacac cacgaatgtg tgcctgatgg
     1501 tgtggcacgt ggccggaact cctgacctcg accgactccg cgccgccgtg tccgcggtgc
     1561 acgagcggca cgaggcgctg ggctcgatct acacgttgga tccccttccc gtggcgctcc
     1621 cccttggttc ggagccaccc gatgtccagg tcctgcccgc tgcctcgtcc ctcgtcgagg
     1681 gggaggcgac gctgacggcg gctctgtcga aggggctcga tccgctcacg ggtagcctgt
     1741 ggcgtgtggc ggtgctccca gtcggttcgg acaccctggt ggggtgtagt gtgcatcaca
     1801 tcgcctttga cggcgcttcc gagtcgatcc tcgcgcggga cctcgcggcc gcctacgacg
     1861 gacatctcca ggtgccgtcg gatctgccct cggtgcgccg actacggaga gtcgaggacg
     1921 tgaccgtggt ctccgccacg ctggctgaac tcgagggtgt tccgccgatc gtgtggcccc
     1981 gggtcgctgc agacgtccga cgcgcactgg ggcacgcctc cgtgcgcttg gacctggacc
     2041 tcgtggcggc ggtggaccgc cgggtgaggg acggggggca cacgcggttt gtcatcctct
     2101 tggctgcatg ggctcatgca ctggctcgag tgatcggggt gcaggacatc gccgtgggcg
     2161 tcccggtctc tcagcgcgct gatccgagcc agcaggatgc ggtagggtgc cacatgacga
     2221 tggtgccgtt gcgcctacgc gcggacgccc ttacgggaga catcgacgcc gtcgatcagg
     2281 tcgtcaggac ggggttcatc cgccaggata tcccgatcac cacgctgctg gcgaactcga
     2341 ccgaccacgg gggacgcccg ccgctgttcc agaccctgtt cggggttcag gacaacccgc
     2401 cgcccatcct tcagctcgac ggtcacatca cgcggttcct ccggcagccc tacttggacc
     2461 tcacccttga gcttcacgcg gaggtatggg tggaggggga ggggctgacg ctggtcgtca
     2521 cccaccgtcc cgacgccgtg cctgacgaga ccgcccacgc tctgctcgag cagttcccca
     2581 agagcctggc cgcgatggtc aacggccggg cgtccgtgcc cgtgtgatcc ccagcgacgg
     2641 ctgagcaggt ccaggcatgg ccgtgcgcgc gggactgatg agcgtgccga tggtgacagt
     2701 catcctcatg cctcctcatc aactcatcga cgggtgcgcc ggggagagct gaagagagct
     2761 caagattcgg catcggcgcc cggacgcacc acacctggtc aggcaagcct aacccgatgc
     2821 gggcgggata accagatgcc cgctaagggt cactaagaac cactaaagcc gctaagagcc
     2881 gctgagggct gttgcgagcc gctaagagcc gctgttccgc gacgcgatct ccagattggt
     2941 ctgacggacc gtattcagca tcatcaggag cacgacgacg gtatagggca gggcgccgat
     3001 acggtgttct gccagatggc tgccgaagtg ctttcgcagc cgat
//
