LOCUS       c00070_3300008..       16421 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300008722.a:Ga0113880_1000255.
ACCESSION   c00070_3300008..
VERSION     c00070_3300008..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 14:09:07
            Original ID  :: 3300008722.a:Ga0113880_1000255
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 52668
            Orig. end    :: 69089
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16421
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[62668:65362](+)"
                     /cutoff="20000"
                     /detection_rule="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C) or cds(LANC_like and (Pkinase or DUF4135)))
                     and not (YcaO or TIGR03882))"
                     /neighbourhood="10000"
                     /product="lanthipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12694
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C) or cds(LANC_like and (Pkinase or DUF4135)))
                     and not (YcaO or TIGR03882))"
                     /neighbourhood="10000"
                     /product="lanthipeptide"
                     /protocluster_number="1"
     cand_cluster    1..16421
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C) or cds(LANC_like and (Pkinase or DUF4135)))
                     and not (YcaO or TIGR03882))"
                     /kind="single"
                     /product="lanthipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..16421
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide"
                     /region_number="1"
                     /rules="((LANC_like and (Lant_dehydr_N or Lant_dehydr_C) or
                     cds(LANC_like and (Pkinase or DUF4135))) and not (YcaO or
                     TIGR03882))"
                     /tool="antismash"
     CDS             1521..1685
                     /gene="allorf_54189_54353"
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="allorf_54189_54353"
                     /protein_id="allorf_54189_54353"
                     /tool="antismash"
                     /transl_table=1
                     /translation="LACPFRSCGSDGIYGLVHCSGATSTIRSRKLAPTAFSLCFPGLCT
                     PPCHGIWLI"
     CDS_motif       1521..1586
                     /tool="antismash"
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: LACPFRSCGSDGIYGLVHCSGA"
                     /locus_tag="allorf_54189_54353"
                     /aSTool="lanthipeptides"
     CDS_motif       1587..1685
                     /peptide="lanthipeptide"
                     /prepeptide="core"
                     /score="-5.90"
                     /leader_sequence="LACPFRSCGSDGIYGLVHCSGA"
                     /tool="antismash"
                     /core_sequence="TSTIRSRKLAPTAFSLCFPGLCTPPCHGIWLI"
                     /leader_location="[54188:54254](+)"
                     /locus_tag="allorf_54189_54353"
                     /alternative_weights="3380.0"
                     /alternative_weights="3398.1"
                     /alternative_weights="3416.1"
                     /alternative_weights="3434.1"
                     /monoisotopic_mass="3359.8"
                     /molecular_weight="3362.0"
                     /aSTool="lanthipeptides"
                     /predicted_class="Class II"
     CDS             1999..2658
                     /locus_tag="ctg70_51"
                     /transl_table=11
                     /translation="LSKYYSIHEFSKIIGVSAQTLRNWDANGKLHPHHTTVSGYRYYSD
                     EQLNQVINVKPKKRITIGYCRVSSHKQKDDLERQIDNVKTYLLAKGQPFEIISDIGSGI
                     DYKKKGLQELIRRISQNQVEKVVVLYKDRLLRFGFELIEYITSLYNCEIEIIDNTEKSE
                     QQELVEDLVQIITVFSCKLQGKRANIAKKLIRELIQEETDGKSHKSNVDTKQCTEN"
     CDS             2606..3769
                     /gene_functions="other (smcogs) SMCOG1192:transposase
                     (Score: 260.9; E-value: 3.1e-79)"
                     /gene_kind="other"
                     /locus_tag="ctg70_52"
                     /transl_table=11
                     /translation="MVKAIKVMLIPNNVQKTKMFQYAGASRFAYNWALAREIENYDKGG
                     KFLSDAELRKEFTKLRHSDEYAWLLNISNNVTKQAIKDACTAYKNFFRGLQKFPRFKSK
                     KRSMPKFYQDNVKIRFSNTHVKFEGFSSSRKANKQKMNWVRLAEHGRIPTNAKYMNPRI
                     SFDGLNWWISVCVEFPDCRETLNDDGVGIDLGIKDLAVCSDGTKYKNINKSQKVKKSEK
                     QKRRLQRSISRSYEKNKKGESYCKTNNVIKKEKLLLKRNHRLTNIRKNYLNQTISEIVD
                     RKPRFICIEDLNVSGMMKNRHLSKAVQAQGFFWFRKQLEYRCSDKGIQLIVADQFYPSS
                     KLCSCCGNVKKDLKLSDRVYRCACGNMIDRDFQASINLKTYGEKFAS"
     CDS             complement(4215..4586)
                     /locus_tag="ctg70_53"
                     /transl_table=11
                     /translation="MPHMSLICHKKDIIYLQIQTRFEYNKFIGSTQSVPSQDFGTVNVT
                     VTFLFVPCLETLANLTAGFPVTGLVFTVTIISGREILLINNVHGNTISGLHFFICIRIE
                     TRCIRKVKISALRKIRKIK"
     CDS             4677..5441
                     /locus_tag="ctg70_54"
                     /transl_table=11
                     /translation="MKQKKIVIIMAGILAAAAAMTGCAEQNKTATQVDYTQNSQGKSEQ
                     TKQKTAEKSQPDKKQVNKSTSGGKENSNQTADKKTKVFASSNNAGDVQNSGNDADNTDD
                     SQNTDDSQNTYVDNNSSENNGSTGDGGNQIDQTADQAMIYDSEGNGRLISQADDGNWYD
                     SDGNCYGSWEDIGRAMDEDGVTDQDGNKYYWTWTAPDDASGKVRDPYDLYSWDPGTNSY
                     IPFQAAESDCSPIGRGNGWYYYDEDSGEYVPW"
     CDS             complement(5584..6471)
                     /locus_tag="ctg70_55"
                     /transl_table=11
                     /translation="MTKTEKAVTWAIEIANDPAHGYDQDNRWGPDYDCSSLVISAWQQA
                     GVPVKTKGAYNTKSMKSVFLSCGFKDVTSSVNLDNGSGMKRGDVLLNIARHTVMHIGNG
                     KVVSASINENGGAHGGTPGDQNGNEIKIQNYYNCPWDCVLRYNEDSTSTDPEPQPTTGN
                     AKIRKGQSYANKFANTGISITGKRDAATKKAAIKVLQTALNKDYGAGLDVDGIWGTNTS
                     NALGKHYVKSGETQYMVTAAEILLLLRAYDPNGVEIPGTFGSGLLSAVKAFQKAQGLTV
                     SGTCDRNTFLKLIS"
     CDS             complement(6659..6994)
                     /gene_functions="other (smcogs) SMCOG1148:hypothetical
                     protein (Score: 58.2; E-value: 2.3e-17)"
                     /gene_kind="other"
                     /locus_tag="ctg70_56"
                     /transl_table=11
                     /translation="MKNNTIGKRIAEARINRNITQEHLEELSGLSVSTISRIETGKYMP
                     TIENLLKLPEILDVGLDYFLYDLLPHNKDIQSPAIQDAVSIMNQMGERQTEYIVKILKI
                     YQASHQD"
     CDS             7113..7667
                     /locus_tag="ctg70_57"
                     /transl_table=11
                     /translation="MDEYTKDLYTMMFSLQTLQNQGITIRETVYKSLDKLLLWNKESEN
                     SKYLELALLHMQAYANMGFALDEENKTIREILKKTGKTREDFFPKGYLLGKRIKLTKSQ
                     VRGMIGRWRPSRDSPMTIGELVDDIIRKVKNHEEGRYIYQYHRTDVTTKGDIEVYELVI
                     NKDESYFYDVKKFRFYTFMEE"
     CDS             7673..8380
                     /locus_tag="ctg70_58"
                     /transl_table=11
                     /translation="MIRIMILDDDEMYLKKEKDITEQYFAEKNVDCTVTIYQNVEWFLL
                     GLNEEKFDMYILDIRMPGENGIEAAREIRRLYPDPVIIFITNFVDYAIEAYEVNTYRYI
                     PKECLKEKLPQAYDALLPGIMEKEERYYIINKRNEVEKLAYSDIFYMKKEGKYVIFVHR
                     RGEVKIRASLSTVEKELNSKEFIISDRGYLANIQHVMKMKGRDLYMRDGNIITVGRERF
                     KGVREAILNYWGV"
     CDS             8384..9865
                     /locus_tag="ctg70_59"
                     /transl_table=11
                     /translation="MLKVLLYGLATFMETGIGVWIFSQTFSERRILEKKYYVLEWLLYS
                     LIFFGIYNFSVSLWQIDKKIEKYVIKVICIYIIGLIAGIIYDIFFVKKKEMVLRRILYI
                     GMIFWLTAQYWAGYQSLLMIILGSGIIVLYVFCYFDCTFKQAYVWNFFYAVNIGLIKEA
                     YVVYAGVFNHKQWDDFYSYPRGHTYQEVIFWILGCLFIFWIIKFNLSVNSIKGILRTRL
                     KELFIIGLLEYVLLIVSIIYKFGTIKKENFVMTACLLAVSNIALIGVYVKFQKKTLEMR
                     NQILDMRCKLMEEEYEELRMSYDRYRCLVHDEKHLLLYIKECLENGELDSCITFLNHYK
                     RESIRYSGVAWTGIPEINFMLNIKVRKMEEKNIFFKVDSKIEKIPMKDIDFVVLLGNLL
                     DNAIEAAEKCEEGKGKITCIFRNINDMFIFKVKNTSIYKPYEKNTKFYTSKKEKDEHGW
                     GIESVKQIVRKYNGEIDFKYDKDFFEVEIIISDNT"
     CDS             9882..10010
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg70_60"
                     /transl_table=11
                     /translation="MNEMNDKIIGNVEKELDEIEIIDTESIEEKLSFIVYGTIVCC"
     CDS_motif       9882..9992
                     /tool="antismash"
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MNEMNDKIIGNVEKELDEIEIIDTESIEEKLSFIVYG"
                     /locus_tag="ctg70_60"
                     /aSTool="lanthipeptides"
     CDS_motif       9993..10010
                     /peptide="lanthipeptide"
                     /prepeptide="core"
                     /score="-5.90"
                     /leader_sequence="MNEMNDKIIGNVEKELDEIEIIDTESIEEKLSFIVYG"
                     /tool="antismash"
                     /core_sequence="TIVCC"
                     /leader_location="[62549:62660](+)"
                     /locus_tag="ctg70_60"
                     /monoisotopic_mass="519.2"
                     /molecular_weight="519.7"
                     /aSTool="lanthipeptides"
                     /predicted_class="Class II"
     CDS             10001..12694
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070:lanthionine synthetase C family protein (Score:
                     763.7; E-value: 5e-231)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg70_61"
                     /sec_met_domain="LANC_like (E-value: 1e-52, bitscore:
                     171.1, seeds: 47, tool: rule-based-clusters)"
                     /sec_met_domain="DUF4135 (E-value: 5e-93, bitscore: 304.3,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VLLKLDYLCRKNRTMFLKILILDVHRQKNFGNLKGSTPKEQYDYY
                     EKKYLNNATYVKSLLQEYPELKRLLELKNNSTQRAECEIGKSLYAEKEQIQKIFCDGRK
                     FSGTVGIYMAKGDIHRGGRSVAKVELDNGTILYYKPHSLDKNIKYQELYNYLCRKTGIS
                     CRTVQYLSHDSYGWEEKIENIPCKNESEVEHYYFRMGIHLFLGYALGATDLHGENIIAH
                     GEYPVIIDMETYPGYLKQQSEKDGSSVEEKINKSTEIKLANSVIHTGMLPVLTWGRGNS
                     RVLISAMGTEEKIKTPFKLPVVKDDKTSDIHIEYEPVEMQIKECIVRLNDQVINAADYT
                     ECIIRGFCRAYMVAMADKKVEVMLSGFFDGRSRVVLRHTQQYAMYLMASFHPDYMKSRE
                     YRKALLNVIHKEGESSFMKEIHDYEIESLLEMDIPCFEIDANSRSVYDGNGGEHKEYLP
                     CTPYESWRMDMKQMSYSDMECQCDYIRLSMEMLKASDGKKKMFPTRIKGYDTDKERKIY
                     SQIRKIVHRICSRAIIREQSVGWTGLQFWDNGHWNLRSGGIYLYDGISGTVLFLAKYLH
                     DFEEKNASAEEIYHLAVLRLKAYTDEIHKKQIYDKNLLTGIVNGESSVVYTYLYLSKLT
                     GKRVWMIYAEKHFSIIERVWKEDSQLDYLSGNAGAIVMAVMLYKETGNLKYYEIAADME
                     KDLWKKGQETGNGYGWRLKGTDGPLAGMSHGNSGFMMAYAALYECNHKAEYADKIQLLL
                     RYEDSLYSEKAGNWKDLRESSGESFMNAWCHGAPGILLSRMKLEELFPEDMQIKKDRLN
                     AADSLFYGEQDEKICLCHGMSGNLLIMKKYLRKYGNKKMKEQYEALCDYLLFQLDHPAK
                     ISGTEYLNLAFMNGISGTGMALMEIL"
     CDS             complement(12747..13271)
                     /locus_tag="ctg70_62"
                     /transl_table=11
                     /translation="MKTLTELIQNYQNGIPDSDSEILKRMEPLVKGYASRIHCMEREDS
                     IQELYLTLLKTLSYLSSSSSEGECIRYMQTSVENRYRSLCRSCLSEPEKDDFDSCSVSL
                     QAPDSFDDTYYDVTAYINSYPSDSVQRKILSMYFYQDKSDAQIARKLKLSRQYVNRMKK
                     KLILRYISKNK"
     CDS             13573..13812
                     /locus_tag="ctg70_63"
                     /transl_table=11
                     /translation="METTVMNVAVSHGIWAVLAVFLLVYIVKSNEKRDEKQEEREKNYQ
                     SVIEKLTEKLEILHQVQSDLSEIKENLFGKHKQE"
     CDS             14101..15339
                     /gene_functions="other (smcogs) SMCOG1242:transposase
                     (Score: 270.9; E-value: 2.4e-82)"
                     /gene_kind="other"
                     /locus_tag="ctg70_64"
                     /transl_table=11
                     /translation="MKDLLEISCGLDVHKEKIVACILTGPLGKPTRSEIREFSTLIPDM
                     IALRNWIVSKNCHHVAMESTGIYWMPIYEILEDAFSGDITLLVVNARHMKNVPGKKTDM
                     RDSEWISTLLRAGLLNGSFIPEKRIREFRDLNRYRKSVIRDITSQKNRIEKFLQSSGFR
                     LSSFISDIFGASGRNIILHLVEHGQIDKTALDSCLKTKTRNRIDEILMSVNGTLSEHQK
                     AFLRILMTHYDSLKKHLAEIETSLEEDMAPFALQVEQLNSIYGISTTASCAIIAEIGID
                     MKPFKTAEHICSWAGLCPGNNESAGKRKSTSVTKGNPYIKSMLCEIAWVIAGKRNTYLS
                     AWYWRIKQKKGAKKAIVALARKLLVIIYTMLKQGTLFDESCFETRRKHCEQKQLSRYIR
                     ELEKHGYHVEAQS"
     CDS             complement(15564..15812)
                     /locus_tag="ctg70_65"
                     /transl_table=11
                     /translation="MKQTFKKPSYYLLSQAMDGDEKAIEKILAFYDPYISKCCLRPLYD
                     EYGNVYIVVDMELKGLIREALIKMILGFDIALEIEEE"
     CDS             complement(15814..16419)
                     /locus_tag="ctg70_66"
                     /transl_table=11
                     /translation="KIEYVLALKARTDYMFCAGFFHTRKKFKNFSKEVIKSHLSFPIWC
                     GKRDKHFSNHSGKGVRLMKPSDFQKTVQCRFESCLKKVVRHVVKDYQQGLKRRKDKEIP
                     FCELPEIFVENFAVRDDYETDYTIFSVCGIDIRVLDDELAEALKKLPERKRNTLLMYYF
                     LEMTESEIANLQKITQSGVFRNRHHALETMKKILKEKQ"
ORIGIN
        1 tagagcattc ctgaacgtat tcattcattt ttgtgatagc ttcttttgca tctgaaacaa
       61 taggaatatc tacctgaatg tttctggaga tagatgcggt gtcgatatcg atgtgtacaa
      121 tctgtgcatg aggtgcaaat tcatgaagtt ttcctgtgat tctgtcattg aatctggttc
      181 cgatagagaa aaggagatca cagttgctga ctgccatatt tgctgcatag gcaccatgca
      241 taccaaggtt tccgatgtag agcggatggt ctgtggggat agagcctttt cccattacgg
      301 ttgtgacaac cggtactttt gtcttttcca ctacttcccg gaagatttca tgggcgcggg
      361 agattactac accgccgcct gccaggaata agggacgttt tgctttattt aaaagtttga
      421 tggcacgttt gagctggccg atgtggacat ctgtgtttgg tttgtatccg cggatgttta
      481 catttttagg atattcagcg ctgccgagtt ctgccattac gtcctttgga aggtcgataa
      541 ggacaggtcc cggacggccg gtgcgggcaa tgtagaaggc ttctttgatg atacgtccca
      601 ggtcttcacg tctgcggaca gtaacaccgt atttggtgat gcttctggtg attcctacga
      661 tgtctacttc ctgaaatgca tcgttgccga tgaggtggcg ggctacctgg ccggtgaagc
      721 atacaagagg tacgctgtca tagttggcgg ttgcaagtcc tgttacaagg ttggttgctc
      781 cgggaccgct ggttaccaga catacgccga ctttgccggt ggttctggcg taggcgtcgg
      841 cttcgtgtac aagggcctgt tcgtgacggg ggaggatgat tttgacatcg tcctgtttgt
      901 agagttcatc actgatgtcg atggtacagg ctccggggta gccgaagagg tattctacgc
      961 cttcttcttt taaggctttg actaagagtt tgttgccgga tatttgtttc atatttgggt
     1021 aaacctcctt tgggtatgtg gatggggacg ctcggaaatt tatttgtttt cgggtgcggt
     1081 ttcggagtct aggaactcta agtgtctgaa aatctgctaa aaccgttcag aaaaatctca
     1141 aactcgccgc agatgcggct cagacagtga gatttttctg aacaacgcag atttccaggc
     1201 actaagagtt actacgactc ctgcaaatgc acccgaaaac aaataaattt ccgagctgtg
     1261 tgttggccaa tacagggtgg ggcagaatgg cgctgcgctg attctgccga gtgtggggcg
     1321 gcgggtttga tgtgacagat taaagcaagc acgaacgact ttttgaccct gatatataaa
     1381 tatagtaaaa aacgccctgg gcttgtttgc ccagggcgaa aatgtttccg cggtaccacc
     1441 tgtattcaga gtctggctct gcactttgtc agtactgata tactgtgttc ctgtaacgtg
     1501 gaactgacgt tgaagcctac ttggcatgtc cgttcaggtc ttgtggatca gacgggatat
     1561 acggtttggt tcactgctcg ggggctactt ccacaattcg ttcacgaaag ctcgcaccga
     1621 ccgctttctc tctgtgcttc ccggggttgt gtactcctcc ctgtcatggc atttggctga
     1681 tatagggata ttcattgtcc gaatagggtg gacaaatgtt ttcttgggtt acattataca
     1741 tttatagaga ggaaattgtc aaccgggttt tggataattg ctgtaaaatt tatgttcctg
     1801 aatgaatttt ggctacgtta ctgagaacgg agtgaacagt aatgtaattg acagatttct
     1861 atattgctga tataaaaaat aaataataca gctgtttgga aggttattaa cagttaaata
     1921 taaattataa aatcatataa gcacatgttg agttttgtaa gatattagag tagaatatta
     1981 ttgaaaggag ttgattcttt gagtaaatat tattctatac atgaattttc aaaaattata
     2041 ggcgtatctg cccagacatt acgaaattgg gatgccaatg gaaaacttca tccgcatcat
     2101 actacagtaa gtggctatag atattattct gatgagcaac tcaaccaggt aataaatgta
     2161 aagcctaaaa aacgcattac aattggatac tgtcgcgttt ccagccataa acagaaagat
     2221 gatctggaac gacagattga taatgttaag acatatcttc tggcaaaagg acagccattt
     2281 gagataataa gtgatatcgg ttccgggatt gattataaga aaaaaggact tcaggaattg
     2341 atcaggcgaa tatctcaaaa tcaggttgaa aaggttgttg ttttgtataa agatcggtta
     2401 ctgcgatttg gttttgagct gatagaatat atcacttcac tttataattg tgagattgag
     2461 atcattgata atactgaaaa atccgaacag caggaacttg ttgaagatct ggttcagata
     2521 atcacagtat tcagttgtaa attacaagga aaacgagcga atatagctaa gaaacttatc
     2581 cgtgaactga tacaggagga aacagatggt aaaagccata aaagtaatgt tgataccaaa
     2641 caatgtacag aaaactaaga tgtttcagta cgcaggtgct tcaagatttg cttataactg
     2701 ggctttggcc agggaaatag aaaactatga caaaggcgga aaattccttt cagatgcaga
     2761 actcagaaaa gaatttacga agcttagaca ttctgatgaa tatgcatggt tactgaatat
     2821 ctcaaataat gtaaccaaac aggcaattaa agatgcctgt actgcttata agaacttttt
     2881 caggggtttg cagaaattcc caagattcaa gtcaaaaaag agatcaatgc cgaagttcta
     2941 tcaggacaac gttaagatac gcttcagtaa tacacacgtt aaatttgaag gcttttcttc
     3001 cagcaggaaa gcaaataaac aaaaaatgaa ttgggtaaga cttgcagaac atggacgtat
     3061 tccgacaaat gctaaatata tgaacccgag aatatccttt gacggattga actggtggat
     3121 cagcgtatgt gtagaatttc ctgactgcag ggaaacactt aatgatgacg gagtcggcat
     3181 agacctggga atcaaagatc tggctgtctg ctctgatggg actaagtata agaacatcaa
     3241 taagagtcag aaagtaaaga aatcagaaaa acagaaacgc aggttacagc gtagtatctc
     3301 tcgttcttac gagaaaaata agaaagggga aagttactgt aaaacaaata atgtaatcaa
     3361 aaaggaaaaa cttttattaa aacgaaatca cagattaaca aacatccgta aaaattattt
     3421 aaatcagacc atatcggaga tcgtagatcg aaaaccaaga tttatatgta ttgaagatct
     3481 gaatgtcagc ggaatgatga aaaacagaca tttatccaaa gcagttcagg cacagggatt
     3541 tttttggttt agaaaacagc ttgaatatag gtgcagcgat aaagggatcc agcttattgt
     3601 ggctgatcag ttttatccat cctcaaaact ttgcagctgt tgtggaaacg tcaaaaaaga
     3661 tctgaagtta tctgacagag tttatagatg tgcgtgtggg aatatgattg acagagattt
     3721 ccaggcatct ataaatctca agacttatgg agaaaaattt gcaagctgac actgaaatgt
     3781 taatgcaaat atgtacggat acgttagtcc ggaatttacg cctatggaga gtacaagaac
     3841 ttgtgagtag attgatattt atattatcaa aagcatactc gttgaagtag gaatggaaca
     3901 taaaagttta taacttttta taagttttca gtaacggaga agaatgaaaa gtaattacaa
     3961 aatttttaca gcagtttttt atcggcaatt atgacagcag cagctccgtt aacagtatgt
     4021 ggggcggaag ttttttcggc gggagaatct ttcagtgatg gaacggggag tattcctgcc
     4081 atattgacag atatggttct gccgggtgga gagattggaa cggaatatca ggtacagctt
     4141 tgatcaatct gggaattcat gcagaggggc agcagtcaca agatcgatta tttctttata
     4201 atgcaggaac agattcactt tatctttctg attttccgca gagcagatat tttgactttt
     4261 cttatgcacc gagtttcgat acgaatacag atgaagaaat gcaacccgga aattgtgttg
     4321 ccgtggacat tgttgataag aagaatctcc ctgccggaaa ttatggtaac tgtaaaaaca
     4381 agccctgtaa caggaaaacc tgctgttaaa ttagctaagg tttccagaca gggaacaaaa
     4441 agaaatgtaa cggtgacgtt tactgttcca aagtcctgtg atggaacaga ctgggtactg
     4501 ccaataaact tattatactc aaatcttgtc tgaatttgga gataaataat gtccttttta
     4561 tgacagataa gggacatatg aggcatcaaa gcctgtggag tatgtaataa tgaacaggaa
     4621 aagcacatta tgataaaggc agtgacattt ttagcaaatg tagaaaggac aacaaaatga
     4681 agcagaaaaa gattgtaatt attatggcag ggattttagc agcagcggct gctatgactg
     4741 gctgtgcgga acagaataaa acagcgacac aggttgatta tacgcagaat tcacagggga
     4801 aatccgaaca gacaaaacaa aaaacagcag aaaaatctca gccggataaa aaacaggtaa
     4861 ataaaagtac atccggtgga aaagaaaatt caaatcagac tgcggataag aagacgaaag
     4921 tatttgcctc atccaataat gcgggcgatg tacagaattc agggaatgat gcggataata
     4981 cagatgattc acagaataca gatgattcac agaatacata cgtggacaat aattcatctg
     5041 aaaataatgg ctcaacaggc gacggtggca atcaaattga tcagacagca gatcaggcga
     5101 tgatatatga cagtgaggga aatggaagac tgatttctca ggctgacgat ggaaactggt
     5161 atgacagtga cggaaattgt tatggaagct gggaggatat tgggcgtgct atggatgaag
     5221 atggtgttac ggatcaggat ggcaataaat actactggac ctggaccgca cctgatgatg
     5281 catcaggaaa agtaagagat ccgtatgacc tgtattcctg ggatccggga accaattcct
     5341 atataccgtt tcaggctgcg gaatctgact gtagtcctat aggcagagga aacggctggt
     5401 attattatga tgaagacagc ggcgaatatg ttccgtggta aaaaataaga aaacaaaaga
     5461 aacagttttg aaatcatttt gatgggtttc aaaactgttt ctttttatat acaagaaata
     5521 gtgaaggggc atatccggca gaatcagtga aaagaattct gccggatgtt tatctggtaa
     5581 agatcagctg atcagtttca ggaaagtatt tctgtcacag gttccggaaa ccgttaagcc
     5641 ctgtgccttc tggaatgcct ttacagcaga gagaagtcct gagccaaagg taccgggaat
     5701 ctctacaccg tttggatcat aagcacgtaa aagaaggaga atctcagcgg cagttaccat
     5761 atactgggtt tcaccgcttt ttacgtaatg tttaccaagg gcattgcttg tgttagttcc
     5821 ccagataccg tctacatcca gaccggcacc ataatctttg ttcagagctg tctgaagaac
     5881 tttaatagct gctttcttag tggcagcatc tcttttcccg gtaatggaga tgccagtatt
     5941 ggcaaattta ttggcataac tctgaccttt gcggattttg gcatttccag tagttggctg
     6001 tggttctgga tccgtagatg tagaatcttc attataacga agaacacaat cccacgggca
     6061 gttgtagtaa ttctggattt taatttcgtt gccattctgg tcacccggag taccaccgtg
     6121 ggctccacca ttttcattta tactggcaga aactactttg ccgttgccga tatgcataac
     6181 tgtatggcgt gcaatgttta acagtacatc accgcgtttc ataccgcttc cgttgtcaag
     6241 attaacactg gaagtaacgt ctttgaatcc gcaagacagg aaaacagact tcatactttt
     6301 ggtattataa gctccttttg tttttacagg tacaccagcc tgctgccatg cagagattac
     6361 cagtgaagaa caatcgtagt ccggtcccca tctgttatcc tgatcatatc cgtgtgccgg
     6421 atcgtttgcg atttcaattg cccatgttac tgctttttct gtttttgtca tttttttatc
     6481 ctcctgaaat ttgattattt atttgctcac cggtgataca tcttataaag agtgagaaaa
     6541 gggaaaaatg taaacatgaa acagaaaaaa ataaaaagca tttcctgatt gttgcttcga
     6601 ggtcagaaaa atgcttttcg aggacaaaaa cacgaaaatt gtcgaattgt aattatattt
     6661 aatcctgatg agaggcctgg tatattttca gtatttttac aatgtattca gtctggcgtt
     6721 cacccatttg attcatgatt gaaaccgcat cctgaatggc cgggctttga atatctttat
     6781 tatgaggaag cagatcataa agaaaatagt caagtcccac atcaagaatt tcaggaagct
     6841 taaggagatt ttcaatagta ggcatatact tacctgtttc aatccggctg atcgtactta
     6901 cagataaacc acttaattct tccaggtgtt cctgggtaat atttctgttg atccgagctt
     6961 ctgcaattct ttttccgata gtattgtttt tcataaataa aaatcctttc ctttgataaa
     7021 gtttaacaga cggaattaaa tatgtataag gatataaatg acaagcgact aatcaaattt
     7081 gatatgtttt atgacaggag gaatatagga atatggacga atatacaaag gatttgtata
     7141 ccatgatgtt ttctttgcag actttgcaaa atcagggaat tacaatcaga gaaactgtat
     7201 ataaaagtct ggacaaatta ctgttatgga ataaagaatc tgaaaacagt aaatatctcg
     7261 aattagcgtt gcttcatatg caggcttatg ctaatatggg atttgcttta gatgaagaaa
     7321 ataagacaat acgtgagata ttaaaaaaga caggaaagac cagagaagac tttttcccga
     7381 aaggatatct tcttggaaag agaattaaac tgaccaagtc acaggttcgt ggtatgattg
     7441 gaagatggag accttccaga gacagtccga tgacaatcgg agaactggtg gatgatatca
     7501 tcagaaaggt aaaaaaccat gaggaaggca gatacattta tcagtatcac agaactgatg
     7561 tgacaaccaa aggggatatc gaggtttatg agctggtcat caataaggat gaaagttatt
     7621 tttatgatgt gaagaaattc agattttata cattcatgga ggaataattg ctatgataag
     7681 aataatgatt ctggatgatg acgaaatgta tctgaaaaaa gaaaaggata tcacagaaca
     7741 gtattttgca gagaaaaacg tagattgcac ggtaacgata taccagaatg tggaatggtt
     7801 tctgctggga ttgaatgaag aaaaattcga tatgtatatt ctggatatcc ggatgcctgg
     7861 agaaaacgga atagaggcag cgagggaaat tcgcagactt tatccggatc cggttattat
     7921 atttattaca aattttgtgg attatgcaat agaagcatat gaggtaaaca cctatcgtta
     7981 tatccccaaa gagtgtctga aggaaaaact tccgcaggct tatgatgcgc ttcttcctgg
     8041 aattatggag aaagaagagc ggtactatat cataaataaa agaaatgaag ttgaaaaact
     8101 ggcatattct gatattttct atatgaaaaa agaaggaaaa tatgtcattt ttgtgcacag
     8161 gcgtggggaa gtaaagatca gagcaagtct gtcaacagta gaaaaggaac tgaattcaaa
     8221 agaatttatt atatctgaca gaggatatct tgcaaacatc caacatgtga tgaagatgaa
     8281 aggaagggat ctttatatgc gggacggtaa tattattaca gttggcagag aaagattcaa
     8341 aggtgtcaga gaagcaattc tgaattactg gggggtatga agaatgctga aagttttatt
     8401 gtatggactg gcaacgttta tggagacagg gataggtgtc tggatattta gccagacgtt
     8461 ttctgaacga agaatattag aaaaaaaata ttatgttcta gaatggctgt tgtattcttt
     8521 gatttttttt ggaatttata atttttctgt ttcattatgg cagattgata aaaaaataga
     8581 aaaatatgtc ataaaagtta tttgtatata cataattgga ttaattgcag gaattatata
     8641 tgatattttt tttgtaaaga aaaaggagat ggtcttaaga agaatattat atatcggcat
     8701 gatattttgg ttaactgctc agtattgggc tggatatcaa tcgttgttaa tgattattct
     8761 tgggagtgga ataattgtat tatatgtttt ttgctacttt gattgcacat ttaaacaggc
     8821 atatgtttgg aattttttct atgcagttaa tataggattg ataaaagagg cttatgttgt
     8881 atatgcaggg gtgtttaacc ataaacagtg ggatgatttt tattcatatc cgagaggaca
     8941 tacatatcag gaagttatat tttggatttt aggctgttta ttcatatttt ggataattaa
     9001 atttaatttg tcagtaaaca gtataaaagg aatattgcgt acacgtctga aggaactttt
     9061 tattattgga ttgttagagt atgttttatt aatagttagc atcatataca aatttggtac
     9121 gattaaaaag gaaaattttg taatgaccgc atgtttatta gcagttagta atatagcatt
     9181 gattggtgta tatgttaagt ttcaaaaaaa gaccctagaa atgagaaatc agattttaga
     9241 tatgagatgc aaattaatgg aagaagaata tgaagaattg agaatgtcat atgaccggta
     9301 tcggtgtttg gtgcacgatg aaaaacattt gcttttatat ataaaagaat gcctggaaaa
     9361 tggagaactg gattcatgta tcactttttt gaatcattac aagagagaaa gcattagata
     9421 tagtggagta gcgtggacag gaattccaga aataaatttt atgttgaata taaaagtgcg
     9481 aaaaatggaa gaaaagaata ttttttttaa agtagattca aaaatagaaa aaattccgat
     9541 gaaagacata gattttgttg tactcctagg aaatcttttg gataatgcaa tagaagctgc
     9601 tgaaaagtgt gaagagggaa aaggtaaaat tacgtgtatt tttcgaaata ttaatgatat
     9661 gtttattttt aaagtaaaga atacaagcat atataaacct tatgaaaaaa acactaaatt
     9721 ttatacaagt aaaaaagaga aagatgagca cggatggggg attgaaagtg tcaaacaaat
     9781 tgtaagaaag tataatggtg aaatagattt taaatatgat aaagattttt ttgaagtaga
     9841 aataataatt agcgataata cataatggga gagtgacggt tatgaacgaa atgaatgata
     9901 aaataatagg aaatgtggaa aaagaattag atgaaataga gataatagat acggaaagta
     9961 tagaagagaa attgtctttt attgtatatg gaactatagt gtgttgctga aattggatta
    10021 tttatgcaga aaaaatcgaa ctatgtttct taaaatatta atcttagatg tacatcggca
    10081 gaaaaatttt ggaaatctaa aaggaagtac gccaaaagaa caatatgatt attatgaaaa
    10141 aaaatatctt aacaatgcaa catatgtaaa atctttactg caggaatatc ccgagttaaa
    10201 acgtctgctt gaattaaaaa ataactctac ccagagggca gaatgtgaaa tcgggaaatc
    10261 tctttatgca gaaaaagaac agatacaaaa aatattctgt gatggaagga agttttccgg
    10321 gactgtggga atttacatgg cgaaaggcga tatacacaga ggaggacgaa gtgtggcaaa
    10381 ggtagaattg gataatggaa caattctgta ctataagcca catagtcttg ataagaatat
    10441 aaaatatcag gaactttata actatttatg cagaaaaaca ggaatttcct gcaggacggt
    10501 acaatattta tctcatgatt cctatggatg ggaagaaaaa attgagaata ttccctgtaa
    10561 aaacgaaagt gaggtggagc attattattt cagaatgggc atacatctgt ttttgggata
    10621 tgcccttgga gcaacagatc ttcatggtga aaatattatc gcacatggag aatatcctgt
    10681 gattatcgat atggaaacgt atccgggata tttaaaacaa caatcagaaa aagacggaag
    10741 tagtgtagaa gaaaaaataa acaaaagtac agaaataaaa ttggcaaatt cggttataca
    10801 tacaggaatg ctccctgttc tcacatgggg cagaggaaac agcagagttc ttataagtgc
    10861 aatgggaaca gaggaaaaga taaaaacacc gtttaaactt cctgtggtaa aggatgataa
    10921 aacatctgat atccacatag aatatgaacc tgtggaaatg cagataaagg aatgcattgt
    10981 aagattaaat gatcaggtta tcaatgcggc agattatacg gaatgcatta tcagaggatt
    11041 ttgcagagcg tacatggtgg caatggcaga taagaaagtg gaggtgatgt tgtccggctt
    11101 ttttgacgga cgttccagag ttgtactgcg gcatacccaa cagtatgcaa tgtatcttat
    11161 ggcttcgttt catccggatt atatgaagtc aagagaatac aggaaagctc ttttgaatgt
    11221 gattcacaaa gagggggaat cttcttttat gaaggagatt catgattatg aaattgagag
    11281 ccttctggaa atggatatac cctgctttga gattgatgcg aacagcagat ctgtttatga
    11341 tggaaatggc ggagaacata aagaatatct gccctgtact ccttatgagt catggcgaat
    11401 ggatatgaag cagatgagtt actctgatat ggaatgtcag tgtgattata tcaggctgtc
    11461 catggaaatg ctgaaggcat ctgatggaaa gaaaaagatg tttccgacca ggataaaggg
    11521 atatgacaca gataaagagc gcaaaatata cagtcagatc agaaagatag ttcatcgaat
    11581 ctgcagcaga gcaattatcc gggaacagag tgttggctgg acaggactgc aattctggga
    11641 taatggtcac tggaacctca gatcaggtgg aatctattta tatgatggaa tatcggggac
    11701 agtcttgttt cttgcaaaat atcttcatga ttttgaagaa aagaatgcaa gtgcagaaga
    11761 aatttatcat cttgctgttt tgagattgaa agcttataca gatgaaatac acaaaaaaca
    11821 gatttatgat aaaaatcttc tgacaggtat tgtaaatgga gaaagctcgg tggtatatac
    11881 ctatctttat ctgtctaaac ttacaggaaa aagagtgtgg atgatttatg cggaaaagca
    11941 tttcagcatt attgagaggg tatggaaaga agattcacaa ctggattatc tgagcggaaa
    12001 tgccggagct attgtaatgg cagtaatgtt atataaagaa accggaaatc tgaaatatta
    12061 tgaaatagcg gcagatatgg aaaaagattt gtggaagaaa ggacaggaaa ccggaaatgg
    12121 atacggatgg agattaaaag gaacagacgg accgctggct ggaatgtctc atggcaacag
    12181 tggatttatg atggcttatg cagcgttgta tgaatgtaat cataaagcgg aatatgctga
    12241 taaaatacag cttttgctga gatatgagga ttctttgtac tcagagaaag ccggaaactg
    12301 gaaggattta cgagagagtt caggggaaag cttcatgaat gcatggtgcc atggggcgcc
    12361 gggaatcctg ctttcacgaa tgaaactgga agagctgttt cctgaggata tgcagattaa
    12421 aaaagacagg ttaaatgctg cagactcttt gttttatgga gaacaggatg aaaaaatttg
    12481 tctgtgtcat gggatgtccg ggaatttact tattatgaag aagtatcttc gaaaatatgg
    12541 taataaaaaa atgaaggagc aatatgaggc gttatgtgac taccttttat ttcaactgga
    12601 tcacccggca aaaatatctg ggacagaata tctgaatctg gcttttatga atggcatttc
    12661 cggtacggga atggcattaa tggaaatttt atgaaaacta agggaacacc tgcagactgt
    12721 aaatttatgg tcagcaggtg tttcttttat ttgtttttgg aaatatatct gagaattagt
    12781 ttcttcttca tccgattgac gtactggcgg gacagcttca gtttccgggc aatctgggca
    12841 tcgcttttat cctgataaaa gtacatggac agaatttttc tctggacact gtccgaaggg
    12901 taagagttga tatatgcggt tacatcataa taggtgtcat caaaactgtc gggagcctgt
    12961 aatgaaacag aacaagaatc aaaatcatct ttttcaggtt cggaaagaca actgcggcaa
    13021 agggaacgat atctgttttc gacagaggtc tgcatgtatc tgatacattc accttctgag
    13081 gatgaagaac ttaaatatga caatgtcttt aacagagtaa gatacaattc ctgtatggaa
    13141 tcttcgcgtt ccatgcagtg aatccgggat gcatatcctt tcacaagcgg ttccatacgt
    13201 ttgagaattt cactgtctga atctgggata ccattttgat aattttggat aagttctgtc
    13261 agtgttttca taggtatcta cctccttttt aggggaagta gtaagaaaac tgctgatcag
    13321 aaactaaaaa agaaaaaaat tatgagttta caaatggaag agaaaaaact ctttattaag
    13381 tgagtttgca aattcaaatt aatgataaga ggagaaaaaa tatatggtaa aaagagattg
    13441 gtagaataat tgtagagaat aaaactgtgc cttaaattgg aacggtaata ataaggccag
    13501 aaaagacttt tagtggatgg aatatagaaa aaaatgcgta ataaaagaag attaagagga
    13561 gggaggtgaa ctatggaaac aacggttatg aatgtggcag tttcgcatgg aatctgggca
    13621 gtgctggcgg tatttctttt ggtttatatt gtgaaatcaa atgaaaaacg agatgagaaa
    13681 caggaagagc gggaaaaaaa ttatcagtct gtaatagaga aactgacaga gaaattagag
    13741 attttacatc aggtacaaag tgatttatca gaaatcaaag agaatctttt tggtaagcat
    13801 aagcaggagt aaaaattcag gtataaaatt gtcaacgaat catgaaagct tatctcagcc
    13861 tataatgaaa ataggatact gactccacta cttttttcac ttctcttttt gccttacaat
    13921 agtcttaggc aggattaagt ttgattgcac cttggaggat ttgcaccccg tttgtcaacg
    13981 taaatgattt gcccttgagc acagcatatt gtcgcacctt ttatgaatag cacgagtagc
    14041 aaagtccgta ttatctcggg caaatctcct gccaattcta tagtaaagga gttgttctgt
    14101 atgaaagacc ttctggaaat ttcctgtgga ctggatgtcc acaaagaaaa aattgttgca
    14161 tgtatcctga ctggtcctct gggcaagcca acccgttctg aaatccgtga gttttctaca
    14221 ttgattccgg atatgatagc attacggaat tggatcgttt ctaaaaactg ccatcatgta
    14281 gctatggaaa gcaccggtat ctattggatg ccgatttatg aaatactgga ggatgctttc
    14341 tctggtgaca ttaccctgct tgttgtaaat gcacgccata tgaaaaatgt tcctggcaaa
    14401 aagaccgata tgcgggattc cgaatggatt tccaccttgc ttcgcgccgg acttttgaac
    14461 ggaagtttta ttcccgaaaa aaggattcgg gaattccgcg atctaaatcg ttaccgtaag
    14521 agtgtcatcc gcgatattac gtcacagaag aacaggattg agaaattttt acaaagttcc
    14581 ggcttccgtc tatcatcctt tatttctgat atttttggcg cttcgggtag aaacatcatt
    14641 ctgcatttag ttgaacatgg gcagattgat aaaactgctt tagattcttg tctcaaaacc
    14701 aagaccagaa accgtattga tgaaattctc atgtccgtga acggaacact gtcagaacac
    14761 caaaaggcat ttttaaggat tctcatgact cattatgatt ctttaaagaa acatcttgct
    14821 gaaattgaaa cgagtctcga ggaagatatg gctccatttg ccctgcaggt tgagcagttg
    14881 aatagcatct atggaataag cacaactgct tcctgtgcaa ttattgctga aatcggtatt
    14941 gatatgaagc cgtttaaaac tgcggaacac atctgctcat gggccggttt gtgcccaggt
    15001 aataacgaaa gtgctggaaa acgaaaaagc acctctgtca caaaaggcaa tccttacata
    15061 aaaagtatgc tctgcgaaat tgcctgggtg attgcaggga aacgcaacac ttatctttcg
    15121 gcatggtact ggagaatcaa acagaaaaaa ggagccaaaa aagcgattgt cgcacttgcc
    15181 cgaaaacttc ttgtcatcat ctacacaatg ttaaaacaag gaactctatt tgacgaatcc
    15241 tgttttgaaa caagacgtaa gcactgtgaa caaaaacagc tttctcgtta tatacgggaa
    15301 ttggaaaaac atggttatca tgtggaagct caaagctagc ctttcttaaa tacgatcaat
    15361 ctctcactac aggcagccaa tactgtgact gctttatagt gatgctttca taattgttga
    15421 aaacatttgt tgtcaaggtt cagtttttgg ctacgagttt tattttcgta gcaagagctg
    15481 tggcgaaagc gtgttgcttt catgtaaaag cagggcagag caggaaagag ggggacatta
    15541 aaccatggtc tgctaaaaac tgcttattct tcttcgattt ctaaggcaat atcaaaccct
    15601 aaaatcattt tgataagtgc ttctcggata agtcccttta actccatatc tacaacaata
    15661 tagacattgc cgtattcatc ataaagtggg cgcaaacagc actttgatat gtacgggtca
    15721 taaaatgcca gtattttttc aatcgctttt tcgtccccgt ccattgcttg cgaaagcaaa
    15781 tagtaggacg gcttcttaaa tgtttgcttc attttactgc ttctccttta gtattttttt
    15841 catagtttcc aaagcatgat gtcggtttct aaatacaccg ctttgcgtaa tcttttgtaa
    15901 gttggcaatt tcactttctg tcatttccaa gaagtaatac attaacagag tatttctctt
    15961 tctttctgga agttttttca aggcttctgc cagctcatca tcaaggacac gaatatcaat
    16021 gccacatact gaaaagattg tataatctgt ttcgtagtcg tccctcacag caaaattttc
    16081 aacgaaaatt tctggaagtt cacagaatgg aatttcttta tcttttcgtc gtttcaatcc
    16141 ttgttggtag tcctttacaa catgacggac aactttcttc aaacaacttt caaagcgaca
    16201 ttgaactgtt ttctggaagt cagacggttt catcaatctc accccctttc cactatgatt
    16261 tgaaaagtgt ttatccctct ttccgcacca tatagggaat gaaaggtgtg atttaatgac
    16321 ctcttttgaa aaatttttaa atttttttcg ggtatgaaaa aagcccgcac aaaacatata
    16381 gtctgtacga gcctttaaag ctaaaacata ttcaattttt a
//
