LOCUS       c00100_3300009..        6302 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300009701.a:Ga0116228_10017438.
ACCESSION   c00100_3300009..
VERSION     c00100_3300009..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 08:10:56
            Original ID  :: 3300009701.a:Ga0116228_10017438
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 6302
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..6302
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2779:3937](-)"
                     /cutoff="20000"
                     /detection_rule="ladderane"
                     /neighbourhood="20000"
                     /product="ladderane"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(2780..3937)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="ladderane"
                     /neighbourhood="20000"
                     /product="ladderane"
                     /protocluster_number="1"
     cand_cluster    1..6302
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="ladderane"
                     /kind="single"
                     /product="ladderane"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..6302
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="ladderane"
                     /region_number="1"
                     /rules="ladderane"
                     /tool="antismash"
     CDS             3..134
                     /locus_tag="ctg100_1"
                     /transl_table=11
                     /translation="TVFLGFSVLSNGIFLTFIQVDISPIDPMPFLGTEFRPESLQMY"
     CDS             complement(319..2598)
                     /locus_tag="ctg100_2"
                     /transl_table=11
                     /translation="MILLKRFSFLLKPSGDIQIFRGIRTFLAIAFPLILGQIIHRPEIG
                     LGIGLTTQALFLADVGGLYSVRAITLIGTTLGMVLAITLGTLLSGSLWLAVLLVFSGLF
                     MAGYLAVYDENGAASGLAIGLTLLFAITLPPGGLVLAIERSLVVLLGGAWATFVALLVW
                     PFLPNQPLRQIVADNFEGIAKYLEDINFRYTSSENDVSSLALLQKLLLESRETLAYTKM
                     GSWGRSNLRELLVVLIEDSDNILITLIAIQELLILHPLPQLQTVEFLLEDAIKQVASIT
                     RDIAQLILGRTKLPDCNRLKLLLTAIEQQQDLQQRALDTGVDDYTIYVTVTHLKNLLKK
                     LQIQLQLATQTAQQLHRGDSVPTHRKHHISGKKAPLQRIPIDEDQWMMELKPWWEPLQE
                     NFNLESPFFRHALRWGLGSAIGVLIYVFLRIPHGLWIGFTIIIVLKPDFSLTFQRFFNR
                     IIGTLLGAVVVTLILEIVHDPFWLQMIGVLCIGIAFSLLRFHYSLAVFFITLYALTFSQ
                     IHLINSHESEVAARAICTLIGATVAFVLSLSFLRPKEELLFSSAAVKAIEKVNLYFQSV
                     MGVYLGNSPYQLAKLMQVRNQVQLANINIQTAIQRLLNDPSTLFTSMEPAIIAANYIPL
                     LGRAVSVILIQLEHYSGSDPHPTVILLTQQIVETLTQLAQSLQNNTLPPPLPILEETVE
                     DILSHIQELRVERLTEIAHNQNSTITHNYLRDYNIVASTLVEIVLRIRTIHAAVSRFEL
                     AASPKS"
     CDS             complement(2780..3937)
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (133-381). E-value:
                     1.7e-41. Score: 134.2. Matches aSDomain:
                     nrpspksdomains_ctg100_3_PKS_KS.1"
                     /NRPS_PKS="type: PKS/NRPS-like protein"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ladderane: ladderane"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 276.8; E-value:
                     5.5e-84)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg100_3"
                     /sec_met_domain="ladderane (E-value: 4.8e-77, bitscore:
                     248.1, seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LVNIVITGIGLVSALGKSLEESWENLLAGKTGIKLYQPFPEQEPL
                     PLGLIGQRPSELSYLTQMVVESVLQDARLEPPLPDCAVVIGSSRGYQASWEKLLRKMSG
                     ENLGLDSASLSLENWLYTLPHMNAIAVAKQIGACGTVLAPMAACATGIWTISQAALLIK
                     SGQYQQAIAGAVEAAITPLTLSGFRQMGALAKTGVYPFDIQREGLALGEGAALFVLESA
                     TSAKQRQAKIYGEILGFGLTSDAYHSNQPEPTGKSLNFAIKQCLANSGLQTKDIDFIHA
                     HGTATQLNDRIESGIIQSLFNQGVAVSSTKGSSGHTLGASGALGVAFSCMALRHQVLPP
                     CVGLQQPEFDLDFVTETRVSQIKQALVLSCGFGGSNTVIALARRG"
     aSDomain        complement(2795..3538)
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg100_3_PKS_KS.1"
                     /evalue="1.70E-41"
                     /label="ctg100_3_PKS_KS.1"
                     /locus_tag="ctg100_3"
                     /protein_end="381"
                     /protein_start="133"
                     /score="134.2"
                     /tool="antismash"
                     /translation="QIGACGTVLAPMAACATGIWTISQAALLIKSGQYQQAIAGAVEAA
                     ITPLTLSGFRQMGALAKTGVYPFDIQREGLALGEGAALFVLESATSAKQRQAKIYGEIL
                     GFGLTSDAYHSNQPEPTGKSLNFAIKQCLANSGLQTKDIDFIHAHGTATQLNDRIESGI
                     IQSLFNQGVAVSSTKGSSGHTLGASGALGVAFSCMALRHQVLPPCVGLQQPEFDLDFVT
                     ETRVSQIKQALVLSCGFGGSNTVIALA"
     aSModule        2795..3538
                     /domains="nrpspksdomains_ctg100_3_PKS_KS.1"
                     /incomplete
                     /iterative
                     /locus_tags="ctg100_3"
                     /tool="antismash"
                     /type="pks"
     CDS             complement(3956..4807)
                     /locus_tag="ctg100_4"
                     /transl_table=11
                     /translation="MRLRFPQFSRFLATLLIIGALILTGCSNEQPASSTSTESIAISQS
                     ATSSPTKLSAQASATDNTPSDIKNSESPAMSNLSRLEGKATVVITVQYQAAPKDQPTPI
                     TIELDGNEAPITAGNFVDLVQKHVYDGTIFHRVVREPQPFVVQGGDPQSKDPKISPNKW
                     GTGGYIDPKTGGQRYIPLEIEPTGETTPIYSQTFESAKISQPPVLRHKQGAVAMARSQM
                     PDSASSQFYIALADLGFLDGNYAVFGYVTQGFEAVNKIQQGDSIVSATVTAGGENFKPA
                     AS"
     CDS             complement(4866..5435)
                     /locus_tag="ctg100_5"
                     /transl_table=11
                     /translation="MTASKTTDQNDRLLHQNVLGSRRFSNYWWAAIVTLGSTGFFLASI
                     SSYFRVNLLIVTDATQLVFVPQGIVMGFYGCAGLLLASYLWLTILWDLGGGYNEFNQET
                     GKFKVFRWGFPGKNRQIEIESNIQDIQSVRVSIKEGLNPQRSIYLRVKARRDIPLTRVG
                     QPLPLDQLETQAAELARFLGVPLEGL"
     CDS             5751..6302
                     /locus_tag="ctg100_6"
                     /transl_table=11
                     /translation="MTIAVGRASVNRGWFDVLDDWLKRDRFVFIGWSGLLLFPCAFLAL
                     GGWLTGTTFVTSWYTHGLASSYLEGANFLTVAVSTPADSMGHSLLLLWGPEAQGDLTRW
                     FQLGGLWPFVALHGAFGLIGFMLRQFEIARLINLRPYNALAFSGPIAVFVSVFLIYPLG
                     QSSWFFAPSFGVAAIFRFLLF"
ORIGIN
        1 aaacagtttt tttgggtttt tcagtgttat ccaatgggat ttttttaact ttcatccaag
       61 tggatatttc cccaattgac cccatgccat tcttaggtac tgaatttaga cctgaatcct
      121 tacagatgta ctagctagag atgcgagcag aattaagcta agattcgcag aacctaaatt
      181 aattttcatc agtaacacct tggtaacgaa tttttcatcc tcccgaatac tacaataaga
      241 cgggtattat ttattagaac ccgtatccca agatcctatt ttattccaag atacttattg
      301 agaattaaac tatacgccct aactcttggg actagcagcc agttcaaaac gagagactgc
      361 ggcgtggata gtccggatac gcaggacaat ttccactaag gtactggcta caatattata
      421 gtctcgcaga taattatggg taatagtact gttttggtta tgagctattt ctgtaaggcg
      481 ttctaccctc aactcctgaa tatgggagag tatatcttct actgtttcct ccaatatcgg
      541 gaggggaggt ggtaatgtgt tgttttgcag ggattgagct agctgtgtca atgtttctac
      601 tatttgttga gtcaataaaa taactgtggg atgaggatcg ctaccgctat agtgttctaa
      661 ttgtattagt attactgata ctgcacgacc taagagagga atgtagttag cggcgataat
      721 agcaggttcc atactagtaa acaaagtgct aggatcgtta agtaatcgtt gtatggcagt
      781 ttggatatta atattggcta attggacttg gttacgcacc tgcattagtt tagctagttg
      841 atagggagaa tttcccaagt aaacccccat gacactttgg aaatagagat taactttctc
      901 gatcgctttc accgcagcac tggaaaacag taattcttcc ttgggacgca gaaaactcaa
      961 cgataagaca aaagcaactg ttgcaccaat tagggtgcag atcgctcgtg ctgctacttc
     1021 actttcatgg gaatttatca gatggatttg actaaaagtt agagcataaa gagtaatgaa
     1081 aaacaccgct aaactataat gaaaccggag tagggaaaag gcaataccta tacataatac
     1141 accgatcatc tgtaaccaaa aaggatcgtg aactatctct aagattaatg tgacaactac
     1201 tgctcctaaa agcgtgccaa taatccgatt gaaaaagcgt tgaaaagtta gactgaagtc
     1261 aggtttaagt actattatta tagtgaaccc aatccaaagt ccgtggggaa tccgcaaaaa
     1321 aacgtaaatc aacacgccaa tggctgaacc taatccccag cgcagagcat gacgaaaaaa
     1381 gggagattct aggttgaaat tttcctgaag tggctcccac cagggtttta attccatcat
     1441 ccattggtct tcatctatgg gaatacgctg taaaggtgct tttttccctg atatgtgatg
     1501 cttgcggtgg gtgggtacgc tatcacccct atgtaattgt tgagcagttt gggtagcaag
     1561 ttgtaactga atctgtaatt tttttaataa gttttttaaa tgagtcacag ttacatagat
     1621 tgtatagtca tcgacacccg tatctagggc tctttgttgt aaatcttgct gttgttcaat
     1681 tgcagttagc aacaatttga ggcgattaca atctggtagc ttagttcttc cgagaattaa
     1741 ctgagcaata tctctggtaa ttgaagctac ttgttttatg gcatcttcga gtaaaaattc
     1801 tacagtctgg agttggggta aaggatggag gatcagtagt tcctgaatag ctatcagagt
     1861 aatcaatata ttatcactat cttcaatcaa taccaccaat aattctcgca gattgctacg
     1921 cccccaacta cccatttttg tatatgctag agtctcacgg gattccaata gtaacttttg
     1981 caaaagagcg agagaagata catcattttc actggacgtg tagcggaaat ttatatcctc
     2041 aagatatttg gcaattccct caaaattatc agcaacaatc tgacgtaatg gttgatttgg
     2101 taaaaaaggc cagaccaaca aagctacaaa agtcgcccaa gctcccccta acaaaactac
     2161 taatgatctt tctatcgcta acaccaatcc tcctggaggt agggtaatag caaatagcaa
     2221 tgttagaccg atggctaaac ctgatgctgc tccattttca tcataaactg cgagatagcc
     2281 agccataaat aagccactaa aaactaacaa cacagccagc caaagtgaac cactcaacaa
     2341 cgttcctagg gttatcgcca aaaccatccc cagggttgta ccaatcaagg ttatcgcccg
     2401 gacggagtac agtccaccaa catctgctaa aaacaatgct tgagtagtca gtccaattcc
     2461 taatcctatt tctggtcgat gaatgatttg accgaggatc aaagggaagg cgatcgccaa
     2521 aaaagtccga attcctctga aaatttgaat gtccccactt ggttttaaga ggaagctaaa
     2581 gcgttttaat aggatcatga atcatacacc tctcttgcta tccaaattaa tcaatattct
     2641 acaagatagt tgtgagataa gggtttcgtt ttctcattac tgaacctatc accaaaaaga
     2701 gctaggaaat agaagtagtt tactttattg aaagatacgc agatatagct tttaaaatta
     2761 aacgtaaaag taatgatttt tatcctctcc tagccaatgc tatgacagta ttactaccac
     2821 caaaaccgca actcaagact agcgcttgct ttatttgact aactctagtt tcagtaacga
     2881 aatccaaatc gaattccggc tgttgtaatc ctacacatgg tggtaagact tggtgacgca
     2941 aagccataca ggaaaaagct acacctaatg cgcctgatgc tccaagggta tgtcctgagc
     3001 tacctttggt tgaactgaca gctactccct gattaaataa actttgaata ataccgcttt
     3061 ctattcgatc attgagttgg gtagcggtac catgagcatg aatgaagtcg atgtctttgg
     3121 tttgtaagcc actatttgct aaacattgct taatcgcaaa attgaggctt tttcctgttg
     3181 gttctggttg gttggaatga tacgcgtctg atgttaagcc aaaacctaga atctctccat
     3241 aaatttttgc ttgacgttgt ttggctgatg tggctgattc taagacgaat aaggctgctc
     3301 cttcccccaa cgctaaacct tctctctgaa tgtcaaatgg gtatactcct gtttttgcta
     3361 aagcccccat ttggcgaaag ccagataagg tcaaaggtgt aattgctgct tctactgctc
     3421 cggcgatcgc ttgttgatat tgaccgcttt taattaacaa agcagcttgg ctgattgtcc
     3481 aaattcctgt agcgcaagcc gccataggcg ctaaaaccgt tccacaagct cctatctgtt
     3541 tggcgacggc gatcgcattc atatgaggta atgtatacaa ccaattctct agggataaac
     3601 ttgctgaatc taaccccaaa ttttcaccag acatctttcg gagtaatttt tcccaagatg
     3661 cttggtaacc acgactagaa ccaatcacca cagcacaatc tggtaaaggt ggctctaaac
     3721 gcgcatcttg taagactgat tcaacaacca tctgagttag ataacttaat tcagatggtc
     3781 gttgaccaat taaacccagg ggaagtggtt cttgctcagg aaatggctgg tataatttaa
     3841 taccagtctt acccgcgagt aaattctccc aactttcctc cagacttttg cctaaggcgg
     3901 aaactaaacc aataccagta ataacaatgt tgaccaaatt aaagggaaaa gttatttaac
     3961 tagcagcagg tttaaaattt tctccacctg cggtaactgt agcagagact atactatcgc
     4021 cttgttggat cttgttaact gcttcaaagc cttgggtaac ataaccaaat acagcataat
     4081 taccatctaa gaagcctaaa tctgctaaag caatatagaa ctgggaagaa gctgaatctg
     4141 gcatttgcga tcgcgccatt gctactgcac cttgtttatg gcgtaaaaca ggtggttggc
     4201 taatcttagc cgattcaaaa gtctgactat aaattggagt tgtttcacca gttggctcaa
     4261 tttctaaagg aatgtaacgt tgtccacctg ttttcgggtc aatataacca ccagttcccc
     4321 atttgtttgg ggaaatcttt gggtctttac tttggggatc accgccctgg actacaaaag
     4381 gttgaggctc gcggacgact cgatgaaata ttgtgccatc ataaacatgc ttttggacta
     4441 aatcaacaaa gttaccggct gtaatcggtg cttcattgcc atctagttcg atagtaattg
     4501 gtgtaggctg atccttaggc gcagcttgat actgaactgt tattactaca gttgctttac
     4561 cttcaagcct tgataagttt gacattgcgg gactctcact attttttata tctgatggag
     4621 tgttatctgt ggcacttgcc tgagcagata gttttgttgg gctagaggtg gctgattgag
     4681 aaatagctat tgattcagta gatgtagacg atgctggttg ctcatttgag catcctgtca
     4741 atatcaaggc accaataatc aagagcgtcg ccaaaaatcg cgaaaattgg ggaaatctta
     4801 accgcatttt aagtatctta gtttgtcact ccataaaagt tcatccaatt ggcttttgca
     4861 cccatctaaa gtccctctaa aggaactcct aaaaaacgtg ctaattcagc cgcttgagtt
     4921 tccaattgat ctagaggtaa tggttgacct acccttgtta ggggaatatc gcgcctagct
     4981 ttgacgcgaa gataaatcga tctttgagga ttcagacctt ctttgataga gacacggaca
     5041 gattgaatat cctgaatgtt gctctcgatc tctatttgcc gattttttcc cggaaatccc
     5101 cagcgaaaca ccttaaattt accagtttct tgattaaatt cgttgtaacc accacctaaa
     5161 tcccagagga tggtgagcca gaggtatgag gctaggagca acccagcaca accataaaac
     5221 cccataacta taccttgagg cacaaatact aattgagtag catcagtcac tataagtaga
     5281 ttaactctaa aatagctgga tatagatgcc aaaaagaagc ctgtagaccc caaagttact
     5341 atagctgccc accaataatt gctaaatcga cgagagccga gaacattctg gtgtagtagg
     5401 cgatcatttt ggtcggttgt ctttgatgcc gtcatgaaac tttctcttga ctgttgagat
     5461 attctctttt ccagagtgcc attttaacag ttaagatggc aagtcagtag atttatgagg
     5521 agatttatga gaaaatttat gtcaaattat taaaattctc ccattttagc gactaaaata
     5581 ttaagtagtt cagacccttc tggggcaaat ctggaacaaa acagttagtt cattcgcgga
     5641 agttcaacgc aactacgggt gaatgtgata agttaaaaat cgttaagata ccacaaccta
     5701 attttatgag tgagtggtag accaaatggc agaatgagga ttttattcaa atgaccatcg
     5761 cagttggacg cgcctctgtt aatagaggat ggtttgacgt tctagacgac tggttgaaac
     5821 gcgatcgctt cgtgttcata ggttggtcag gactgttatt atttccttgc gctttcctcg
     5881 cattaggcgg ttggcttaca ggtacaacct tcgttacatc ttggtacacc cacggattag
     5941 cttcctcata cttagaaggc gctaacttcc tgactgtagc agtatccacc ccagccgata
     6001 gcatgggaca ttccctgtta ttgctttggg gaccagaagc ccaaggtgac ttaactcgtt
     6061 ggtttcaatt gggcggacta tggcctttcg tagctctcca cggagccttt ggattgattg
     6121 ggttcatgct gcgccaattt gaaattgccc gcttgattaa ccttcgtccc tataacgcct
     6181 tggcattttc tggaccaatt gcagtatttg tcagcgtgtt tttaatttac cccttgggac
     6241 aatccagctg gttctttgct cccagttttg gcgtagcagc aattttccgt ttcttattat
     6301 tc
//
