LOCUS       c00169_3300009..        3678 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300009701.a:Ga0116228_10042970.
ACCESSION   c00169_3300009..
VERSION     c00169_3300009..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 08:10:56
            Original ID  :: 3300009701.a:Ga0116228_10042970
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 3678
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..3678
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2:2213](+)"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3..2213
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
     cand_cluster    1..3678
                     /SMILES="NC(C(C)CC)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /kind="single"
                     /product="NRPS-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..3678
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS-like"
                     /region_number="1"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX))"
                     /tool="antismash"
     CDS             3..2213
                     /NRPS_PKS="Domain: AMP-binding (13-280). E-value: 5.3e-75.
                     Score: 244.2. Matches aSDomain:
                     nrpspksdomains_ctg169_1_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (388-456). E-value: 5.6e-25. Score:
                     79.1. Matches aSDomain: nrpspksdomains_ctg169_1_PCP.1"
                     /NRPS_PKS="Domain: Thioesterase (475-725). E-value:
                     2.6e-36. Score: 117.9. Matches aSDomain:
                     nrpspksdomains_ctg169_1_Thioesterase.1"
                     /NRPS_PKS="type: NRPS-like protein"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     274.4; E-value: 2.5e-83)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg169_1"
                     /sec_met_domain="AMP-binding (E-value: 9.9e-92, bitscore:
                     294.6, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 3.7e-21, bitscore:
                     62.7, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="QLISRSLQENPMTESQATNLAYVIYTSGSTGQPKGVAVTHRAVNR
                     LVLNTNYIHLTPDDHIAQAANISFDAATFEIWGALLYGARLVIIPKSVLLSPSEFAVNL
                     RIQEITVLFLTTALFNQLVSFVPQAFSSLRYLLFGGEAVESRWVQEVLEKGAPHQLLHV
                     YGPTENTTFSSWYLVEELLITGTNIPIGRAISNTQIYVLNQNLQPVPIGVPGELYIGGD
                     GLARGYLNRPELTAERFIQNPFSDDKSERLYKTGDLARYLSDGNIEYIGRIDQQVKIRG
                     FRIELGEIEAVLNSHAQIQQTVVIATEDLTGNKRLVAYIVSEDESLSTHQLRDFLKSKL
                     PEYMVPSAFVTLDTLPLTPNGKVDRKALPAPDGEISREHEYVAPRTAIELQLTQIWSSI
                     LGIAPVGVRDNFFELGGHSLLAVRLMSQIQQHFQINLPLATLLQNPTIEQLVHLLHSSP
                     DSLPWSTLVPIKSHGNKPPLFCIHPVGGNVLCYQDLASYLTLEQPFYGLQAVGLNPQNQ
                     PHTSIEQMATHYIQELQTVQPHGPYFLSGWSFGGLVAFEMAQQLSYQGEQIALLALIDT
                     YPIFQELEDDAALLVTLALLREDLDICLKDICLEDICLEQLRQFALDEQLNYVIKQAKQ
                     KNLVPEDFDLAQARHLLKICKLNIQASQIYQPQYYSGSVVLFKASETDADLEFTWKSLI
                     EYLETYVVPGNHQNMLRSTHVKVLAEKLQKSLEQAQTNQLEK"
     aSDomain        42..842
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg169_1_AMP-binding.1"
                     /evalue="5.30E-75"
                     /label="ctg169_1_AMP-binding.1"
                     /locus_tag="ctg169_1"
                     /protein_end="280"
                     /protein_start="13"
                     /score="244.2"
                     /specificity="consensus: ile"
                     /tool="antismash"
                     /translation="ESQATNLAYVIYTSGSTGQPKGVAVTHRAVNRLVLNTNYIHLTPD
                     DHIAQAANISFDAATFEIWGALLYGARLVIIPKSVLLSPSEFAVNLRIQEITVLFLTTA
                     LFNQLVSFVPQAFSSLRYLLFGGEAVESRWVQEVLEKGAPHQLLHVYGPTENTTFSSWY
                     LVEELLITGTNIPIGRAISNTQIYVLNQNLQPVPIGVPGELYIGGDGLARGYLNRPELT
                     AERFIQNPFSDDKSERLYKTGDLARYLSDGNIEYIGRIDQQVKIRG"
     aSModule        42..2177
                     /complete
                     /domains="nrpspksdomains_ctg169_1_AMP-binding.1"
                     /domains="nrpspksdomains_ctg169_1_PCP.1"
                     /domains="nrpspksdomains_ctg169_1_Thioesterase.1"
                     /final_module
                     /locus_tags="ctg169_1"
                     /monomer_pairings="ile -> ile"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       63..122
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg169_1_0001"
                     /evalue="4.90E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg169_1"
                     /protein_end="40"
                     /protein_start="20"
                     /score="34.3"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGQPKGVAVTHR"
     CDS_motif       630..719
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg169_1_0002"
                     /evalue="1.30E-20"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg169_1"
                     /protein_end="239"
                     /protein_start="209"
                     /score="65.3"
                     /tool="antismash"
                     /translation="PIGVPGELYIGGDGLARGYLNRPELTAERFI"
     CDS_motif       807..872
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg169_1_0003"
                     /evalue="1.80E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg169_1"
                     /protein_end="290"
                     /protein_start="268"
                     /score="39.1"
                     /tool="antismash"
                     /translation="YIGRIDQQVKIRGFRIELGEIEA"
     aSDomain        1167..1370
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg169_1_PCP.1"
                     /evalue="5.60E-25"
                     /label="ctg169_1_PCP.1"
                     /locus_tag="ctg169_1"
                     /protein_end="456"
                     /protein_start="388"
                     /score="79.1"
                     /tool="antismash"
                     /translation="ELQLTQIWSSILGIAPVGVRDNFFELGGHSLLAVRLMSQIQQHFQ
                     INLPLATLLQNPTIEQLVHLLHSS"
     aSDomain        1428..2177
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg169_1_Thioesterase.1"
                     /evalue="2.60E-36"
                     /label="ctg169_1_Thioesterase.1"
                     /locus_tag="ctg169_1"
                     /protein_end="725"
                     /protein_start="475"
                     /score="117.9"
                     /tool="antismash"
                     /translation="PPLFCIHPVGGNVLCYQDLASYLTLEQPFYGLQAVGLNPQNQPHT
                     SIEQMATHYIQELQTVQPHGPYFLSGWSFGGLVAFEMAQQLSYQGEQIALLALIDTYPI
                     FQELEDDAALLVTLALLREDLDICLKDICLEDICLEQLRQFALDEQLNYVIKQAKQKNL
                     VPEDFDLAQARHLLKICKLNIQASQIYQPQYYSGSVVLFKASETDADLEFTWKSLIEYL
                     ETYVVPGNHQNMLRSTHVKVLAEKLQKSL"
     CDS_motif       1431..1460
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg169_1_0004"
                     /evalue="9.60E-04"
                     /label="NRPS-beforete1"
                     /locus_tag="ctg169_1"
                     /protein_end="486"
                     /protein_start="476"
                     /score="12.1"
                     /tool="antismash"
                     /translation="PLFCIHPVGGN"
     CDS_motif       1611..1685
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg169_1_0005"
                     /evalue="5.00E-16"
                     /label="NRPS-te1"
                     /locus_tag="ctg169_1"
                     /protein_end="561"
                     /protein_start="536"
                     /score="50.9"
                     /tool="antismash"
                     /translation="QPHGPYFLSGWSFGGLVAFEMAQQLS"
     CDS             2215..3540
                     /gene_functions="transport (smcogs) SMCOG1020:major
                     facilitator transporter (Score: 300.5; E-value: 3.1e-91)"
                     /gene_kind="transport"
                     /locus_tag="ctg169_2"
                     /transl_table=11
                     /translation="MLKPLKIEGMSIFVLVWLGQLVSVLGSSLSNFALDVWVYQQSGSV
                     TQLSFLILFTTLPLVIISPFAGVLSDHWNRRWVMILSNSGAALSTLTIALLLITRHIPQ
                     IWHIYLATAISSSFSAFQWPAYSAATTLLVPKKHLGRASGMIQLAQAIATLLSPILGGV
                     LLVFIQLSGIFVLDLSSFLFALTTLLLVRFPQHKVTQSQQPNKTSLLTQALHSFYYLKV
                     RSGLLALLLFFASSNFLVGILQVLTYPLILSFASPAQLGTIMSVGGVGMITGSLVMSIW
                     GGKRQKYINILFGFMLLQGFSMIVAGLYRSIFMFAIAAFLFFLGRPFINSCAQVIFHKK
                     VAPDVQGRVFSLNSAICGSCLPLAYLVAGPLSDRIFEPLMTVNGSLAGSIGQVIGTGSG
                     RGIGLMFIVLGTLTMLMTIIAYQYAPLRLVEDQLPDVVYEDV"
ORIGIN
        1 ggcaactaat ttctcggtct ctgcaggaaa atccaatgac tgagagccaa gcaactaatt
       61 tagcttatgt aatttatacc tctggctcta caggccagcc taagggagta gccgtaactc
      121 accgggctgt aaatcgactg gttttaaata cgaactacat tcatttaaca cctgatgacc
      181 acattgctca agcggcaaat atttcttttg atgctgccac ctttgaaatt tggggagcac
      241 tactgtacgg tgccagacta gtgataattc ctaaatctgt attgctttcg ccttcagaat
      301 tcgctgtaaa tttacgcatc caagaaatca ccgtcttatt tttaaccact gctttattca
      361 atcagttagt cagttttgta ccccaagcat ttagttcttt aagatatcta ctatttggtg
      421 gtgaagcggt tgaatcaaga tgggtacaag aagtactaga aaaaggtgct ccacatcaac
      481 tgctgcatgt ctatggaccc acggaaaata cgactttttc ttcttggtac ttggtagagg
      541 aattactaat tacaggcaca aatatcccca ttggtcgtgc aatttccaac acgcaaatat
      601 atgtgctgaa ccaaaactta caacctgtgc cgataggtgt acctggagaa ctctacatag
      661 gaggtgatgg attagccaga ggctacctga accgtccaga actaacagca gaaagattta
      721 ttcaaaatcc attctctgat gacaaatcag aacgccttta caaaacaggg gatcttgccc
      781 gctacctaag tgatggaaac atagaataca ttggtcgcat agaccagcaa gtgaagattc
      841 ggggtttccg catcgaactt ggggaaatag aagcagtgct caacagccat gctcaaatcc
      901 aacaaaccgt agttattgcc acagaagatc tgactggaaa caaacgctta gtagcctata
      961 tagtcagtga agatgaatca ctcagtaccc accaactacg tgacttcctg aagtcaaagc
     1021 taccagaata catggtgccg tctgcctttg tcaccttaga caccctaccc ttaacaccta
     1081 acggtaaagt agaccgtaaa gccctacccg cacctgatgg ggaaattagc cgagaacatg
     1141 aatacgtcgc accacgtaca gccatagaac tgcaactgac tcaaatttgg tcatctattc
     1201 tgggtattgc tccagtggga gttcgagaca acttctttga acttgggggt cattcccttc
     1261 tagctgtccg cctaatgtcc cagattcaac aacatttcca gatcaattta cctttagcta
     1321 cccttttaca aaatcctacc atcgaacaac tagtgcatct tctccattcc tcaccagatt
     1381 ctttaccttg gtccacacta gtacccatca aatctcatgg caataaacca cctttgttct
     1441 gtattcatcc tgtgggggga aatgtccttt gctatcagga tttagcctct tatctaacct
     1501 tagaacaacc attctatgga ttacaagctg ttggtcttaa tcctcaaaat caacctcata
     1561 ctagtatcga acagatggca actcactata tccaagagtt acaaactgtt caaccgcatg
     1621 gtccttattt tctctctggc tggtccttcg gtggcttggt agcttttgaa atggcgcaac
     1681 aactttccta ccaaggtgaa cagatagctc tgctggctct tatagatact tatccaattt
     1741 ttcaagaact agaagacgat gctgccctat tagtaacgtt agcgttactg agagaagatt
     1801 tggatatctg tttaaaggat atctgtttag aggatatctg tttagagcaa ctgcggcaat
     1861 ttgcactaga cgagcagcta aactatgtaa taaaacaggc taaacagaaa aatctagttc
     1921 cagaggattt tgacttagct caagctcgcc atcttctgaa gatttgcaag ctcaacattc
     1981 aagccagtca aatttaccaa cctcaatatt actcaggctc agttgttcta ttcaaagcca
     2041 gtgaaactga tgccgacctt gaatttacct ggaagtccct aatagaatat ctagaaactt
     2101 acgtggttcc tggtaatcat caaaacatgc tccgatcaac tcatgtcaag gtactggcgg
     2161 aaaaactcca aaaatctctt gaacaagcac agaccaatca attagaaaaa tgaaatgctc
     2221 aaaccactca aaattgaagg aatgtccatc tttgttctgg tctggttggg gcaattagtc
     2281 tccgttttag gctcaagtct cagcaacttt gccctagatg tttgggttta tcagcagagt
     2341 ggttccgtta cccagttatc ttttctgatt ctgttcacta ccctccccct agtaataatt
     2401 tctccctttg ctggtgtctt atcagaccat tggaatcgcc gttgggtgat gattctcagc
     2461 aattccggtg cagctttaag taccctgact atagccttat tactgatcac cagacatata
     2521 ccacaaatct ggcatatata tctagcaact gctataagtt ccagctttag tgctttccag
     2581 tggccggctt atagtgccgc tacaaccttg cttgtaccca aaaaacactt aggtcgagcc
     2641 agtggaatga ttcagttagc acaagccata gcaacactcc tttctcctat tctaggtggt
     2701 gtactcctag tattcataca gctatcagga atttttgttc tggacttaag cagttttctc
     2761 tttgccttaa ctaccctact cttggttcgg tttccccagc acaaagtcac acaaagccag
     2821 caacccaata aaacctcact actcacacaa gcccttcaca gtttctatta tctgaaggtt
     2881 cgctccggac tcctagcgct attattgttt tttgctagta gcaacttcct tgtgggaatt
     2941 cttcaagtac tcacctatcc cctcatactc tcctttgctt ccccagccca acttggcacg
     3001 atcatgtctg ttggcggtgt gggcatgatc acaggtagcc tggttatgag tatttgggga
     3061 ggtaagcggc aaaaatatat caatatatta ttcggcttta tgctgcttca aggattttcc
     3121 atgatagttg caggacttta tcgttcaatt tttatgtttg ccatagctgc ttttctattt
     3181 tttcttggac gcccttttat caacagttgc gctcaagtga tttttcacaa gaaagttgct
     3241 cccgatgtac agggaagagt cttctccctt aatagtgcaa tctgtggctc ctgtttaccc
     3301 ctagcttatc ttgttgcagg tcccctatct gacagaatat ttgaaccttt gatgacagta
     3361 aatggttcct tagccggaag catcggacaa gtcatcggta ccggatctgg gcgaggtatt
     3421 ggtctgatgt ttattgtttt gggaacctta actatgttga tgactattat tgcctatcag
     3481 tatgctccgt taaggttggt ggaagatcaa ttgccagatg tcgtctatga ggatgtttga
     3541 aaacagcaat tctcattttg aaaaaaatag agtattaacc ctgattttgg aattgggtag
     3601 tggtaaatat gtagtgagac ataaatatat taattaaata gcattattat atttatcgct
     3661 atttcatcat ggtttata
//
