LOCUS       c00245_3300009..        3846 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300009709.a:Ga0116227_10049909.
ACCESSION   c00245_3300009..
VERSION     c00245_3300009..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 08:49:43
            Original ID  :: 3300009709.a:Ga0116227_10049909
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 3846
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..3846
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[691:3846]"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      692..3846
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..3846
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..3846
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="(cds(Condensation and (AMP-binding or A-OX)) or
                     (Condensation and AMP-binding))"
                     /tool="antismash"
     CDS             2..571
                     /locus_tag="ctg245_1"
                     /transl_table=11
                     /translation="LLRQGQVVALVAILDTTAPIAHGKIHQKPQELDDAQWLINIAKSL
                     QIAFAKDLEMDAQPLLSLDPNEQLKYVLEYFHMLSVLPPDADTTYLKHLLQAYKAHHMV
                     EYVPQQINPVPITLFCSSEFLSDEPIVLPSEFLQDESWGWSQFSSEPVDIQLVPGNHVS
                     MMTQPHVQVLAERLNACMKQRSRLNG"
     CDS             692..2827
                     /NRPS_PKS="Domain: CAL_domain (44-487). E-value: 7.9e-125.
                     Score: 408.8. Matches aSDomain:
                     nrpspksdomains_ctg245_2_CAL_domain.1"
                     /NRPS_PKS="Domain: ACP (633-703). E-value: 2.1e-16. Score:
                     51.7. Matches aSDomain: nrpspksdomains_ctg245_2_ACP.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     371.4; E-value: 9.4e-113)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg245_2"
                     /sec_met_domain="AMP-binding (E-value: 2e-95, bitscore:
                     307.4, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 4.9e-14, bitscore:
                     40.5, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VLSAKQVSPKITNLIKLLRYRAFEQPNLRAFTFLHNGEIESASLT
                     YKELDEQATAIALQLQSLVSIGERALLLYPPGLEFLAAFFGCLYAGVIAVPAYPPKSNQ
                     KLSRLQAIVQDAQARLTLTTETLLTNIKGWFAQDPQLAALYCLATDSIDFHPADSWQET
                     TLNSNSLAFLQYTSGSTGTPKGVMVSHGNLMCNSDYMHQIWEFSSESVMVTWLPTFHDM
                     GLIYGILQPLYHGFPCYLMSPTSFIQKPICWLQAISRYQGTHSGAPNFAYELCVRKITP
                     EQRATLNLSSWHMTLNGAEPVRVDTLKRFTEVFKPCGFDLTTFCPGYGLAEATLVVAGV
                     QNKKVPSFYTVEAEALKQNQIMDGKTENKVQTFIGHGQPGIDTKVVIVDSESLTQCLPD
                     KVGEIWVSGSTVAQGYWQRTEETKQTFGAYLADSKEGPFLRTGDLGFIKDGELLITGRL
                     KDVIIIRGQNHYPQDIELTVEQSHPALRASCGAAFGIEVDGVERLVIAQEVERSYLHKL
                     NINEVVGAIRKVVSEQHHLQVYAVLLLKTASIPKTSSGKIQRRACRSRFLNRSLDIVGE
                     WTVANPQQLDLEQLQAEVESLWSDVGDSSWYNLEEKVQAISRSSTDLSNPITKERIQAW
                     LVSHLSLNLQIQPNDIDIQESFAYYGIDSTMAISIIDELMKWLQCDLDPTLLWEYSNIE
                     SLAQHLAEQHSQMQTVA"
     aSDomain        824..2152
                     /aSDomain="CAL_domain"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg245_2_CAL_domain.1"
                     /evalue="7.90E-125"
                     /label="ctg245_2_CAL_domain.1"
                     /locus_tag="ctg245_2"
                     /protein_end="487"
                     /protein_start="44"
                     /score="408.8"
                     /specificity="Minowa: NH2"
                     /tool="antismash"
                     /translation="TYKELDEQATAIALQLQSLVSIGERALLLYPPGLEFLAAFFGCLY
                     AGVIAVPAYPPKSNQKLSRLQAIVQDAQARLTLTTETLLTNIKGWFAQDPQLAALYCLA
                     TDSIDFHPADSWQETTLNSNSLAFLQYTSGSTGTPKGVMVSHGNLMCNSDYMHQIWEFS
                     SESVMVTWLPTFHDMGLIYGILQPLYHGFPCYLMSPTSFIQKPICWLQAISRYQGTHSG
                     APNFAYELCVRKITPEQRATLNLSSWHMTLNGAEPVRVDTLKRFTEVFKPCGFDLTTFC
                     PGYGLAEATLVVAGVQNKKVPSFYTVEAEALKQNQIMDGKTENKVQTFIGHGQPGIDTK
                     VVIVDSESLTQCLPDKVGEIWVSGSTVAQGYWQRTEETKQTFGAYLADSKEGPFLRTGD
                     LGFIKDGELLITGRLKDVIIIRGQNHYPQDIELTVEQSHPALRAS"
     aSModule        824..2800
                     /domains="nrpspksdomains_ctg245_2_CAL_domain.1"
                     /domains="nrpspksdomains_ctg245_2_ACP.1"
                     /incomplete
                     /locus_tags="ctg245_2"
                     /starter_module
                     /tool="antismash"
                     /type="unknown"
     CDS_motif       1202..1261
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg245_2_0001"
                     /evalue="7.40E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg245_2"
                     /protein_end="190"
                     /protein_start="170"
                     /score="30.8"
                     /tool="antismash"
                     /translation="AFLQYTSGSTGTPKGVMVSHG"
     CDS_motif       1892..1969
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg245_2_0002"
                     /evalue="2.80E-10"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg245_2"
                     /protein_end="426"
                     /protein_start="400"
                     /score="32.4"
                     /tool="antismash"
                     /translation="VGEIWVSGSTVAQGYWQRTEETKQTFG"
     CDS_motif       2054..2116
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg245_2_0003"
                     /evalue="6.50E-06"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg245_2"
                     /protein_end="475"
                     /protein_start="454"
                     /score="18.7"
                     /tool="antismash"
                     /translation="TGRLKDVIIIRGQNHYPQDIEL"
     aSDomain        2591..2800
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg245_2_ACP.1"
                     /evalue="2.10E-16"
                     /label="ctg245_2_ACP.1"
                     /locus_tag="ctg245_2"
                     /protein_end="703"
                     /protein_start="633"
                     /score="51.7"
                     /tool="antismash"
                     /translation="AWLVSHLSLNLQIQPNDIDIQESFAYYGIDSTMAISIIDELMKWL
                     QCDLDPTLLWEYSNIESLAQHLAEQH"
     CDS             2989..3846
                     /NRPS_PKS="Domain: Condensation_LCL (60-285). E-value:
                     6.4e-62. Score: 201.0. Matches aSDomain:
                     nrpspksdomains_ctg245_3_Condensation_LCL.1"
                     /NRPS_PKS="type: NRPS-like protein"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     174.3; E-value: 8.2e-53)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg245_3"
                     /sec_met_domain="Condensation (E-value: 5.3e-51, bitscore:
                     161.1, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLTELLENLSAKNVELWVQGDKLRYRGSENVLTPELLTQIKQHK
                     LEIIQILSQGSGHEVTYPPSHGQKALWFLYQLAPNSLAYNSTYAARLVTSLNIPALKQA
                     AQALVERHPVFSTTFTTIDGEPVQTVHKHQQVDFRVEDTFALTQDDINNWLLQTSARPF
                     DLEVGPIVRFNLLINHTATTEYILLITQHHIIMDFWSSGIMVSELQLLYEAITLDREPL
                     LPVQKCQYSDYLSWSEQMLAGPTGESLWNYWQQQLCGELPVLNLPTDRPRPQIQTYNGE
                     SLFFR"
     aSDomain        3169..3843
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg245_3_Condensation_LCL.1"
                     /domain_subtype="Condensation_LCL"
                     /evalue="6.40E-62"
                     /label="ctg245_3_Condensation_LCL.1"
                     /locus_tag="ctg245_3"
                     /protein_end="285"
                     /protein_start="60"
                     /score="201.0"
                     /tool="antismash"
                     /translation="TYPPSHGQKALWFLYQLAPNSLAYNSTYAARLVTSLNIPALKQAA
                     QALVERHPVFSTTFTTIDGEPVQTVHKHQQVDFRVEDTFALTQDDINNWLLQTSARPFD
                     LEVGPIVRFNLLINHTATTEYILLITQHHIIMDFWSSGIMVSELQLLYEAITLDREPLL
                     PVQKCQYSDYLSWSEQMLAGPTGESLWNYWQQQLCGELPVLNLPTDRPRPQIQTYNGES
                     LFFR"
     aSModule        3169..3843
                     /domains="nrpspksdomains_ctg245_3_Condensation_LCL.1"
                     /incomplete
                     /locus_tags="ctg245_3"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       3235..3345
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg245_3_0001"
                     /evalue="4.30E-12"
                     /label="C2_LCL_024-062"
                     /locus_tag="ctg245_3"
                     /protein_end="119"
                     /protein_start="82"
                     /score="38.4"
                     /tool="antismash"
                     /translation="AYNSTYAARLVTSLNIPALKQAAQALVERHPVFSTTFT"
     CDS_motif       3562..3624
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg245_3_0002"
                     /evalue="8.40E-09"
                     /label="C3_LCL_132-143"
                     /locus_tag="ctg245_3"
                     /protein_end="212"
                     /protein_start="191"
                     /score="28.0"
                     /tool="antismash"
                     /translation="HHIIMDFWSSGIMVSELQLLYE"
ORIGIN
        1 gttactgcgt caaggtcagg tagtggctct agttgccatt cttgatacca cagcacccat
       61 cgcccacgga aagatacacc aaaagccaca agaactggat gatgctcagt ggctgattaa
      121 cattgccaaa agcctgcaaa ttgcctttgc aaaggatttg gagatggatg ctcaacctct
      181 gctatcttta gatccaaacg agcaacttaa atatgttcta gagtactttc acatgctttc
      241 ggttctgcct ccggatgccg ataccacgta tttgaagcat ttgctgcaag cttacaaggc
      301 tcatcatatg gttgaatatg taccacaaca aatcaatcct gtcccaatta ctttgttttg
      361 ttccagtgag tttctttcag atgaacccat agttttaccc tcagagtttt tacaggatga
      421 gtcttggggg tggagccagt tttctagcga accagtggat atccagttgg tcccaggaaa
      481 ccatgtgagt atgatgactc aaccccacgt ccaagtttta gccgaacggt tgaatgcttg
      541 catgaagcag cgttcaaggt tgaacgggta attataagaa aaatgaggct gaaatccgaa
      601 aaacggttga aatagttaaa tgataacttt tggataattt ttgtcatgta gagtcatggc
      661 aatgttttaa gttttaagga ttctctatca agtgctgagt gcaaaacaag tgtctccgaa
      721 aatcaccaat ttaatcaagc tcctacgcta cagagctttt gagcagccaa accttcgagc
      781 ttttacattt ttacacaatg gggaaataga aagcgcaagc ctgacgtaca aagaattgga
      841 tgaacaagca acagcgatcg cactccagtt acaatccctt gtttccatag gcgaacgagc
      901 cttgctactg tatccgcctg gattagaatt tctcgccgcc tttttcgggt gtttgtacgc
      961 aggagtgatc gcagttccgg cttatccacc caagtctaat caaaagctgt cccgactaca
     1021 ggcaattgtc caagatgctc aggcacggct aactctgacc actgaaactt tattaaccaa
     1081 catcaagggt tggtttgccc aagatccaca attagcagca ttgtactgtt tagctaccga
     1141 tagcatagat tttcatccag ctgactcatg gcaggaaaca actttaaaca gcaatagcct
     1201 agcttttctc cagtacactt cagggtcaac gggaacacca aagggtgtga tggtgagtca
     1261 tggcaacctg atgtgtaatt cagattacat gcaccaaatt tgggagttca gttcagaaag
     1321 cgtcatggta acctggcttc ctacattcca tgatatggga ctgatctatg gcattctcca
     1381 gcccttgtat catggatttc cctgttacct gatgtcaccc acatctttta ttcaaaaacc
     1441 gatttgctgg cttcaagcaa tttcgcgcta ccaaggaact catagtggcg ctccgaattt
     1501 tgcctatgag ctttgtgtcc gcaaaataac tcccgaacaa cgcgccaccc tcaatttgag
     1561 tagctggcac atgactttaa acggtgccga accagtcaga gtagacactt tgaaacgttt
     1621 tacagaagtt ttcaaacctt gcggatttga cctaactacc ttttgtcctg gctacggttt
     1681 agctgaagcc accttagtag tagctggggt gcaaaacaaa aaggtgccaa gtttctacac
     1741 tgttgaggca gaagcactca aacaaaatca gataatggac ggcaaaacag agaataaagt
     1801 acagaccttc ataggtcacg gacaaccagg gattgatact aaggtcgtca ttgttgattc
     1861 cgaatcattg actcaatgtt taccagataa agtaggagaa atttgggttt ccggctctac
     1921 cgttgcccaa ggctactggc agcgaactga ggaaacaaag caaacttttg gggcgtattt
     1981 agcagatagc aaagagggtc catttctccg gacgggagat ttaggattta taaaagatgg
     2041 cgagttgttg atcacaggac gactaaaaga tgtcatcatc attcggggtc aaaaccatta
     2101 ccctcaagac attgaactca ccgtagaaca gagccatcca gcactgcgag ctagttgtgg
     2161 tgcagcattt gggattgaag tcgatggcgt tgaacgattg gtgattgcac aagaggtaga
     2221 gcgaagttac ctgcacaagc tgaatatcaa tgaagtcgtt ggagctatcc gaaaggttgt
     2281 gtccgagcag catcatctgc aagtttatgc cgtgttgcta ctaaagactg ctagtatccc
     2341 aaaaacttct agtggcaaaa ttcagcgccg tgcttgtcgc agtcggtttc tcaataggag
     2401 tctggatata gttggtgagt ggactgtcgc aaatcctcaa caacttgact tagaacagct
     2461 acaggcagaa gtagaatcct tatggtcgga tgtgggagat tcctcatggt acaatcttga
     2521 agaaaaagtg caagcaatca gtaggagtag taccgacctg tctaacccaa tcacaaaaga
     2581 aaggattcaa gcctggttgg tttctcatct cagtctgaac ttacaaatac agccgaatga
     2641 tatagatatt caagaatcct ttgcctacta cggtatagat tcaacaatgg caattagcat
     2701 tattgatgaa ttgatgaagt ggctacagtg cgatctggat ccgactctct tatgggagta
     2761 ctcaaatatt gagtcccttg cccagcatct agcagaacaa cacagtcaga tgcaaacagt
     2821 tgcgtaatga tttcacaccc aaagaaagtt caaatggagc caattgtgag aaagtaaaaa
     2881 actcaagcaa aaataacgaa gaattgaacc ctcagtgcac tacctgaccc tctcagcaaa
     2941 aagtgagcag gctgtgtgtg ttcaaaacaa atgtattgaa ggagaactat gaatttaaca
     3001 gaactgctag aaaatctttc agcaaagaat gtagaactgt gggtgcaagg ggacaagttg
     3061 cgttaccgag ggtctgaaaa cgtactaacc cctgagttat tgactcaaat taagcaacac
     3121 aagctagaaa ttatccaaat tctatcccaa ggtagtggtc atgaagttac ttacccccca
     3181 tcccacggtc aaaaggcgct gtggtttttg tatcagttag cacccaatag tttggcttac
     3241 aacagcacat atgcagcaag attagtcact tctttaaata ttccagccct gaagcaggcg
     3301 gcacaagccc tagtagaaag gcatccagtt ttcagcacga cctttacaac cattgatggg
     3361 gaacctgtgc aaacagttca caaacaccag caagttgact ttagggtcga agatactttc
     3421 gctctaactc aagatgacat caacaactgg ctattacaaa caagtgctcg ccctttcgac
     3481 ttagaagtag ggccaatagt gcggtttaat ttgttaatta accatacagc aacaacagaa
     3541 tatattctgt taataacgca acatcacata atcatggatt tctggtcttc cggaatcatg
     3601 gttagtgaac tacaactgtt gtatgaagca attactttag atagagagcc attattgcct
     3661 gtacaaaagt gtcagtatag tgattacctg tcttggtcag agcaaatgct ggctggtcca
     3721 acaggggaga gtttgtggaa ttactggcag caacaactgt gtggtgagtt gccagtgcta
     3781 aatttgccga cggatagacc cagacctcag atccaaacct ataatgggga atccctcttt
     3841 tttaga
//
