LOCUS       c00377_3300009..        6707 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300009709.a:Ga0116227_10026243.
ACCESSION   c00377_3300009..
VERSION     c00377_3300009..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 08:49:43
            Original ID  :: 3300009709.a:Ga0116227_10026243
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 6707
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..6707
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[728:6707](+)"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      729..6707
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..6707
                     /SMILES="NC(CO)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..6707
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="(cds(Condensation and (AMP-binding or A-OX)) or
                     (Condensation and AMP-binding))"
                     /tool="antismash"
     CDS             complement(3..278)
                     /locus_tag="ctg377_1"
                     /transl_table=11
                     /translation="MSNFEKLINNELFYRFYKSMLRVNISYLVLLTGFLTSHKKSIHQR
                     VTDAIICLLMANGITRISHKRSLRYYQNLSPAYSLSVLDAVSIMTVR"
     CDS             729..6707
                     /NRPS_PKS="Domain: CAL_domain (36-480). E-value: 8.4e-144.
                     Score: 471.7. Matches aSDomain:
                     nrpspksdomains_ctg377_2_CAL_domain.1"
                     /NRPS_PKS="Domain: ACP (603-671). E-value: 5.9e-14. Score:
                     43.9. Matches aSDomain: nrpspksdomains_ctg377_2_ACP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (694-988). E-value:
                     7.4e-100. Score: 325.5. Matches aSDomain:
                     nrpspksdomains_ctg377_2_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (1167-1567). E-value:
                     3.8e-123. Score: 402.8. Matches aSDomain:
                     nrpspksdomains_ctg377_2_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (1708-1774). E-value: 3e-22. Score:
                     70.4. Matches aSDomain: nrpspksdomains_ctg377_2_PCP.1"
                     /NRPS_PKS="Domain: Condensation_DCL (1804-1988). E-value:
                     6.1e-42. Score: 135.5. Matches aSDomain:
                     nrpspksdomains_ctg377_2_Condensation_DCL.1"
                     /NRPS_PKS="type: NRPS"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     374.2; E-value: 1.4e-113)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg377_2"
                     /sec_met_domain="Condensation (E-value: 4.7e-73, bitscore:
                     232.9, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 4.2e-132, bitscore:
                     427.6, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 3.5e-15, bitscore:
                     43.6, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEFSTLIEILRWRALQQPEQKAYSFLQDGEVEESNWTYGKLNCQA
                     RAIAALLQSQGLSGERALLLYPPGLEYIAAFFGCLYAQVIAVPAYPPRLNRSMDRLQAI
                     VADAQATVVLTTTTILTQMERQWSLAPDLKTIKWLTTDRTPSGLEDSWQEIAVNSDTLA
                     FLQYTSGSTSLPKGVMVSHGNILHNETIIQKAMQHTEETIFVGWLPLFHDMGLIGNMLQ
                     SLYLGIPCILMSPVAFLQRPLRWLQAISRYQATTSGGPNFAYDLCVSKITQEQRATLDL
                     SSWQIAFNGSEPIRAQTIERFTAAFTQCGFRREVFYPCYGMAETTLIVSGGLKAVPPVL
                     LSVQKAALGQNRVVATPSKKVGVQTLVGCGQPLQDLQIVIAHPETATRCAPNEVGEIWV
                     QGPSVAVGYWNQIEQTKQTFQVYLTDSEEGPFLRTGDLGFLQEGELFITGRLKDLIVIR
                     GRNHYPQDVEKTVEQSHSALQLGSSAAFSIETALEERLVVAVEVKRNYLRNLNVDEVIR
                     AIRHAVLEEHELQVYGVLLLKTGSIPKTSSGKIQRYACRSGFLSGNLDIVGSSILEDSY
                     TPESEVMLSQEALRALTPDERHFKLASYLQEQVAQVLKVTPSQLDFQQPLSGVGLDSLI
                     AIELQNRIETNLGVVLPMARFLEGSSIDQLADEVLDKFSTSAFPQETTLTPGLKANTAN
                     SLSYGQQALYFLHQLAPESAAYNIVGAARLQAELNIPALGRAFQSLVERHPMLRTTFTN
                     LSGQPIQEIHEHWEVCFQQEDVSTWSEACLNDRLVAEAHRPFNLEQGPLLRVNLFTRSP
                     QEHTLLLVVHHLIADFWSGAVLMHELGILYQMHKAGTKATLSQLPLRYTDYVRATAAML
                     ASPEGERLSTYWQTQLAGELPVLNLPTDRPRPPIQTYRGASHLLKLSADLTQRLKTLSL
                     THRSTLYMTLLAAFQVLLYRYTGQEDLLVGSPTIGRNRADLAQLVGYFVNPVVLRANLS
                     GNPTFKVFLDKVRSCVIDALAHQDYPFPRLVEQLHLTRDPSRSPLFQVMFVLQKEHLLE
                     EGLAAFALGETGVKIKLGELELESLSVEKRIAQFDLTLMMAEVDGALSASWQYNTDLFD
                     AATITRTAKHFQTLLEGIVTDPKKLVSDLLLLTDSEQLQLLQEWNATFADYSSNYCLHQ
                     LFETQVEQTPDAVAVVFVEEQLTYQELNQRANQLAHHLQVLGVKPEVLVGIYLERSPEM
                     IVSLLGVLKAGAAYVPLDPTYPNERLAFMLENAQVSVLLTQEKFVERLPEHKARVVCLD
                     KDAEVLHHQSIDNPVGNVTANNLAYVIYTSGSTGKPKGVMNTHRGICNRLFWMQETYQL
                     TTLDRVLQKTPFSFDVSIWEFFWPLMTGASLVVARPGGHQDSSYLVKLIQQQQITTLHF
                     VPSMLQVFLEEPDIETCNCLRKVMCSGEVLPFQLQERFFTYLDAELHNLYGPTEAAIDV
                     TFWACERESHRHIVPIGRPIANTQIYLLDAQLQQVPIGVPGELHISGAGLARGYLNQPE
                     MTAEKFIPNPFSDEPGARLYKTGDLARYLQGSIIEYLGRIDHQVKIRGCRIELGEIEAI
                     LHQHPTVIEAIVLSRETEFVAKPSWENRVIDPAITELRQFLKGNLPEAEPTNKRLVAYC
                     VTRQQPTPTTTDLRRFLKQKLPDYMIPSSIVILNSLPLMPNGKVDRQSLPDPFDARPDL
                     ETVFVAPRTPVEDALAKIWAQVLEIEQVGIHDNFFELGGDSIRSIQVRAQAQVRGLSFS
                     LQQIFQHQTIYKLAQELSITEPSSLSTPKIEEFALISQQDQQKLPSSVEDAYPLARSQA
                     GLIFHTQSSTDSSIYHDIFLYHLRIHLDLHIFQKVVQELVDRHTILRTSFDLTNFTEPL
                     QLVHKTVSVSVQVEDFRSLSGEQQTEAQKTWIETEKSRHFDWTRPPLVRFCIHRLDNES
                     FYLVLSFYDAILDGWSTASLLTELLHRYCQLLDREESPIEPPPTVKYRDFVALEQKNIE
                     S"
     aSDomain        837..2168
                     /aSDomain="CAL_domain"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg377_2_CAL_domain.1"
                     /evalue="8.40E-144"
                     /label="ctg377_2_CAL_domain.1"
                     /locus_tag="ctg377_2"
                     /protein_end="480"
                     /protein_start="36"
                     /score="471.7"
                     /specificity="Minowa: NH2"
                     /tool="antismash"
                     /translation="TYGKLNCQARAIAALLQSQGLSGERALLLYPPGLEYIAAFFGCLY
                     AQVIAVPAYPPRLNRSMDRLQAIVADAQATVVLTTTTILTQMERQWSLAPDLKTIKWLT
                     TDRTPSGLEDSWQEIAVNSDTLAFLQYTSGSTSLPKGVMVSHGNILHNETIIQKAMQHT
                     EETIFVGWLPLFHDMGLIGNMLQSLYLGIPCILMSPVAFLQRPLRWLQAISRYQATTSG
                     GPNFAYDLCVSKITQEQRATLDLSSWQIAFNGSEPIRAQTIERFTAAFTQCGFRREVFY
                     PCYGMAETTLIVSGGLKAVPPVLLSVQKAALGQNRVVATPSKKVGVQTLVGCGQPLQDL
                     QIVIAHPETATRCAPNEVGEIWVQGPSVAVGYWNQIEQTKQTFQVYLTDSEEGPFLRTG
                     DLGFLQEGELFITGRLKDLIVIRGRNHYPQDVEKTVEQSHSALQLG"
     aSModule        837..2741
                     /domains="nrpspksdomains_ctg377_2_CAL_domain.1"
                     /domains="nrpspksdomains_ctg377_2_ACP.1"
                     /incomplete
                     /locus_tags="ctg377_2"
                     /starter_module
                     /tool="antismash"
                     /type="unknown"
     CDS_motif       957..992
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg377_2_0001"
                     /evalue="2.80E+01"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg377_2"
                     /protein_end="88"
                     /protein_start="76"
                     /score="-0.7"
                     /tool="antismash"
                     /translation="FGCLYAQVIAVPA"
     CDS_motif       1215..1274
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg377_2_0002"
                     /evalue="1.60E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg377_2"
                     /protein_end="182"
                     /protein_start="162"
                     /score="23.7"
                     /tool="antismash"
                     /translation="AFLQYTSGSTSLPKGVMVSHG"
     CDS_motif       1899..1985
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg377_2_0003"
                     /evalue="1.80E-09"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg377_2"
                     /protein_end="419"
                     /protein_start="390"
                     /score="29.9"
                     /tool="antismash"
                     /translation="PNEVGEIWVQGPSVAVGYWNQIEQTKQTFQ"
     CDS_motif       2070..2132
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg377_2_0004"
                     /evalue="8.20E-04"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg377_2"
                     /protein_end="468"
                     /protein_start="447"
                     /score="12.2"
                     /tool="antismash"
                     /translation="TGRLKDLIVIRGRNHYPQDVEK"
     aSDomain        2538..2741
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg377_2_ACP.1"
                     /evalue="5.90E-14"
                     /label="ctg377_2_ACP.1"
                     /locus_tag="ctg377_2"
                     /protein_end="671"
                     /protein_start="603"
                     /score="43.9"
                     /tool="antismash"
                     /translation="YLQEQVAQVLKVTPSQLDFQQPLSGVGLDSLIAIELQNRIETNLG
                     VVLPMARFLEGSSIDQLADEVLDK"
     aSDomain        2811..3692
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg377_2_Condensation_LCL.1"
                     /domain_subtype="Condensation_LCL"
                     /evalue="7.40E-100"
                     /label="ctg377_2_Condensation_LCL.1"
                     /locus_tag="ctg377_2"
                     /protein_end="988"
                     /protein_start="694"
                     /score="325.5"
                     /tool="antismash"
                     /translation="SLSYGQQALYFLHQLAPESAAYNIVGAARLQAELNIPALGRAFQS
                     LVERHPMLRTTFTNLSGQPIQEIHEHWEVCFQQEDVSTWSEACLNDRLVAEAHRPFNLE
                     QGPLLRVNLFTRSPQEHTLLLVVHHLIADFWSGAVLMHELGILYQMHKAGTKATLSQLP
                     LRYTDYVRATAAMLASPEGERLSTYWQTQLAGELPVLNLPTDRPRPPIQTYRGASHLLK
                     LSADLTQRLKTLSLTHRSTLYMTLLAAFQVLLYRYTGQEDLLVGSPTIGRNRADLAQLV
                     GYFVNPVVLRANLS"
     aSModule        2811..6050
                     /complete
                     /domains="nrpspksdomains_ctg377_2_Condensation_LCL.1"
                     /domains="nrpspksdomains_ctg377_2_AMP-binding.1"
                     /domains="nrpspksdomains_ctg377_2_PCP.1"
                     /locus_tags="ctg377_2"
                     /monomer_pairings="ser -> ser"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       2868..2981
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg377_2_0005"
                     /evalue="3.60E-16"
                     /label="C2_LCL_024-062"
                     /locus_tag="ctg377_2"
                     /protein_end="751"
                     /protein_start="713"
                     /score="51.5"
                     /tool="antismash"
                     /translation="AAYNIVGAARLQAELNIPALGRAFQSLVERHPMLRTTFT"
     CDS_motif       3189..3254
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg377_2_0006"
                     /evalue="5.80E-06"
                     /label="C3_LCL_132-143"
                     /locus_tag="ctg377_2"
                     /protein_end="842"
                     /protein_start="820"
                     /score="19.0"
                     /tool="antismash"
                     /translation="VHHLIADFWSGAVLMHELGILYQ"
     CDS_motif       3594..3683
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg377_2_0007"
                     /evalue="7.30E-13"
                     /label="C5_LCL_267-296"
                     /locus_tag="ctg377_2"
                     /protein_end="985"
                     /protein_start="955"
                     /score="40.9"
                     /tool="antismash"
                     /translation="DLLVGSPTIGRNRADLAQLVGYFVNPVVLRA"
     CDS_motif       3732..3851
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg377_2_0008"
                     /evalue="2.30E-22"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="ctg377_2"
                     /protein_end="1041"
                     /protein_start="1001"
                     /score="71.4"
                     /tool="antismash"
                     /translation="RSCVIDALAHQDYPFPRLVEQLHLTRDPSRSPLFQVMFVLQ"
     aSDomain        4230..5429
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg377_2_AMP-binding.1"
                     /evalue="3.80E-123"
                     /label="ctg377_2_AMP-binding.1"
                     /locus_tag="ctg377_2"
                     /protein_end="1567"
                     /protein_start="1167"
                     /score="402.8"
                     /specificity="consensus: ser"
                     /tool="antismash"
                     /translation="FETQVEQTPDAVAVVFVEEQLTYQELNQRANQLAHHLQVLGVKPE
                     VLVGIYLERSPEMIVSLLGVLKAGAAYVPLDPTYPNERLAFMLENAQVSVLLTQEKFVE
                     RLPEHKARVVCLDKDAEVLHHQSIDNPVGNVTANNLAYVIYTSGSTGKPKGVMNTHRGI
                     CNRLFWMQETYQLTTLDRVLQKTPFSFDVSIWEFFWPLMTGASLVVARPGGHQDSSYLV
                     KLIQQQQITTLHFVPSMLQVFLEEPDIETCNCLRKVMCSGEVLPFQLQERFFTYLDAEL
                     HNLYGPTEAAIDVTFWACERESHRHIVPIGRPIANTQIYLLDAQLQQVPIGVPGELHIS
                     GAGLARGYLNQPEMTAEKFIPNPFSDEPGARLYKTGDLARYLQGSIIEYLGRIDHQVKI
                     RG"
     CDS_motif       4416..4457
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg377_2_0009"
                     /evalue="5.10E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg377_2"
                     /protein_end="1243"
                     /protein_start="1229"
                     /score="19.5"
                     /tool="antismash"
                     /translation="LGVLKAGAAYVPLDP"
     CDS_motif       4650..4709
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg377_2_0010"
                     /evalue="8.60E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg377_2"
                     /protein_end="1327"
                     /protein_start="1307"
                     /score="33.6"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGKPKGVMNTHR"
     CDS_motif       5217..5306
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg377_2_0011"
                     /evalue="1.10E-17"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg377_2"
                     /protein_end="1526"
                     /protein_start="1496"
                     /score="56.0"
                     /tool="antismash"
                     /translation="PIGVPGELHISGAGLARGYLNQPEMTAEKFI"
     CDS_motif       5394..5459
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg377_2_0012"
                     /evalue="1.20E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg377_2"
                     /protein_end="1577"
                     /protein_start="1555"
                     /score="36.5"
                     /tool="antismash"
                     /translation="YLGRIDHQVKIRGCRIELGEIEA"
     aSDomain        5853..6050
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg377_2_PCP.1"
                     /evalue="3.00E-22"
                     /label="ctg377_2_PCP.1"
                     /locus_tag="ctg377_2"
                     /protein_end="1774"
                     /protein_start="1708"
                     /score="70.4"
                     /tool="antismash"
                     /translation="EDALAKIWAQVLEIEQVGIHDNFFELGGDSIRSIQVRAQAQVRGL
                     SFSLQQIFQHQTIYKLAQELSI"
     aSDomain        6141..6692
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg377_2_Condensation_DCL.1"
                     /domain_subtype="Condensation_DCL"
                     /evalue="6.10E-42"
                     /label="ctg377_2_Condensation_DCL.1"
                     /locus_tag="ctg377_2"
                     /protein_end="1988"
                     /protein_start="1804"
                     /score="135.5"
                     /tool="antismash"
                     /translation="EDAYPLARSQAGLIFHTQSSTDSSIYHDIFLYHLRIHLDLHIFQK
                     VVQELVDRHTILRTSFDLTNFTEPLQLVHKTVSVSVQVEDFRSLSGEQQTEAQKTWIET
                     EKSRHFDWTRPPLVRFCIHRLDNESFYLVLSFYDAILDGWSTASLLTELLHRYCQLLDR
                     EESPIEPPPTVKYRDFVALEQK"
     aSModule        6141..6692
                     /domains="nrpspksdomains_ctg377_2_Condensation_DCL.1"
                     /incomplete
                     /locus_tags="ctg377_2"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       6216..6323
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg377_2_0013"
                     /evalue="2.30E-09"
                     /label="C2_LCL_024-062"
                     /locus_tag="ctg377_2"
                     /protein_end="1865"
                     /protein_start="1829"
                     /score="29.6"
                     /tool="antismash"
                     /translation="YHDIFLYHLRIHLDLHIFQKVVQELVDRHTILRTSFD"
     CDS_motif       6558..6611
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg377_2_0014"
                     /evalue="6.10E-05"
                     /label="C3_DCL_135-156"
                     /locus_tag="ctg377_2"
                     /protein_end="1961"
                     /protein_start="1943"
                     /score="15.7"
                     /tool="antismash"
                     /translation="ILDGWSTASLLTELLHRYC"
ORIGIN
        1 caacggactg tcatgattga cactgcgtct aaaacgctca aactataagc gggacttagg
       61 ttttggtaat agcgtagcga tcgcttgtga gaaatgcggg taatgccgtt agccatcaat
      121 aagcagataa tggcatcagt taccctttgg tgaattgatt ttttatggct tgtgagaaat
      181 ccggtaagga gaactaaata actaatattt acccttagca tactcttata aaatctataa
      241 aataattcgt tatttataag cttttcaaaa tttgacatca tgtcaaattt gctttctctt
      301 atttgagaaa atctggcagc aaaatggttg acaagtagaa tgacactctt gtattctaaa
      361 aaagagttac tatatattca ataagtaata ttattcaact atggacgctg aaagctaatc
      421 agaaaaaccc tttgggagat atggcatttc ccaagtttta tattgaaaac gcaactgaga
      481 gtctgaacga tctttcataa cttttgatgg agagacgaaa tgggatgctc tctaataggc
      541 aagaatttca agctttatat tcttttttca acctggagaa agtgggaatt tatccaaatc
      601 tttacaagaa aataatttca gcaatttgcc ttttgccagt ctgacaaaag aaagtttgta
      661 atagatgacc tttaccccat ataaagtaag taattgcaca aatgggcaaa cacttttcca
      721 aacgaatgat ggagttctcc acgttgatag aaattctccg ttggagagcg cttcaacagc
      781 ccgaacagaa agcctattct tttctgcagg atggagaggt agaagagtct aattggactt
      841 atgggaaact caattgtcaa gctagagcca ttgctgcctt acttcagagc cagggactta
      901 gtggagagcg tgctttgctg ctctacccgc cagggttgga atatattgcc gctttttttg
      961 gatgcctgta cgcccaagtt attgctgtac ctgcttatcc acctcggttg aaccgatcca
     1021 tggatcgtct ccaagcaatt gtagcggatg cccaggcgac tgtggtgctc acaaccacaa
     1081 cgatcttgac ccaaatggag cgtcagtggt ctctagcacc agacctcaag acgataaaat
     1141 ggctgaccac tgacaggact ccaagtggtc tagaagacag ttggcaggag attgcggtaa
     1201 atagcgatac cttggctttt ctacaataca catcaggttc tacctcacta ccgaagggcg
     1261 tcatggtgag ccatggcaac atattacata acgaaacaat catccaaaaa gccatgcagc
     1321 acacagagga gactatcttt gtgggctggc tccctctgtt tcatgacatg ggtctaattg
     1381 ggaatatgct tcagtccctg tacttgggta tcccatgcat cctcatgtct ccggtggctt
     1441 ttctgcaacg ccccctgcgc tggctacaag caatttcgcg ttatcaagca accaccagtg
     1501 gtggacccaa ctttgcctac gatctatgcg tgagcaagat tactcaagaa caacgggcaa
     1561 ctcttgacct aagtagttgg cagattgctt tcaacggatc tgaacctatc cgtgcccaga
     1621 ccattgaacg gtttacagca gcctttaccc agtgtggctt tcgtcgcgaa gttttctacc
     1681 cctgttatgg catggctgaa acaaccctaa ttgtctctgg tggcttgaaa gcggttccac
     1741 cagtccttct gtctgtccaa aaagcagcat tggggcaaaa tcgggtagtt gctactcctt
     1801 caaagaaggt aggtgtccag acattagtgg gttgtggtca acccctacaa gatctacaaa
     1861 ttgtcattgc ccatcccgaa actgcaaccc gttgcgcccc taatgaggta ggtgaaattt
     1921 gggttcaagg acccagcgta gctgttggct attggaacca aatcgagcaa acaaagcaga
     1981 cttttcaggt atacctaaca gacagtgagg aagggccgtt tctacgcact ggagatttgg
     2041 gttttttgca ggaaggcgaa ctgttcatta ctggtcgcct taaagaccta atcgtcattc
     2101 gtggccgcaa ccattatcca caggacgttg aaaaaacagt ggagcaaagc cactcagcat
     2161 tgcagcttgg tagtagtgcg gcattttcaa ttgagactgc tctggaagag cggttggtag
     2221 tcgcagtaga agtgaagcgc aattatctcc gaaatctgaa tgtggatgag gtcattagag
     2281 ctatccgtca tgcagtgttg gaagaacacg agttacaagt ttacggggtg ttgctgctta
     2341 agactgggag catcccaaaa acttctagtg gcaagattca acgctatgcc tgtcgatctg
     2401 gcttcttgag tggaaatcta gatattgtag gtagcagcat cctcgaagac tcctatactc
     2461 cagaaagcga agtgatgctt agccaggaag ctttaagagc attgacacct gatgagcgtc
     2521 acttcaagtt agcatcttat cttcaggagc aggtggctca ggttctcaaa gtcaccccat
     2581 cccagttgga cttccagcag cccttaagtg gtgtgggtct tgattcttta atagctattg
     2641 aacttcaaaa tcggattgaa actaacctgg gtgtagtctt gccaatggcg agatttctag
     2701 agggttctag tattgaccag cttgcagatg aagtattgga caagttttcg acatctgcct
     2761 ttccccaaga aacgactctt actcccggct tgaaagcgaa cactgcaaat tccctctcct
     2821 acggtcaaca agccttgtac tttctgcatc agttggcacc ggaaagcgcc gcctacaata
     2881 ttgtaggtgc agctcgtctt caggcagagt taaacattcc agcattgggt cgcgcttttc
     2941 aaagcttggt ggagcgccat cccatgttaa gaaccacctt cacgaacctc tcagggcaac
     3001 ctattcagga gattcacgaa cactgggaag tttgtttcca gcaggaggat gtttcaacct
     3061 ggagcgaggc ttgcttgaat gatcgcctag tcgcagaagc ccatcgtccc ttcaatctag
     3121 agcagggtcc cctactaagg gtcaacttat tcacgcgatc gccacaggaa cacactctcc
     3181 tgctggttgt gcatcaccta atcgccgatt tctggtctgg tgcagtgctg atgcatgagc
     3241 taggaatact ttaccagatg cataaagctg gtacaaaagc aaccctgagt cagctaccac
     3301 tgcggtacac cgactatgtt cgtgcaacag ctgcaatgct ggcaagtccg gaaggtgaac
     3361 ggctatcaac ttactggcag acgcaactag ctggggaatt gccagtgctg aatctgccga
     3421 ctgaccgccc tcgaccaccc attcaaacct atagaggagc ctcacacctc ttaaaactga
     3481 gtgcagatct gactcaaagg ctcaagaccc ttagtctcac ccaccgatcc actctctaca
     3541 tgaccttgct agcagccttt caagtgctac tctaccgcta cacaggtcaa gaagatctgc
     3601 tggtaggttc cccgaccatc ggtagaaatc gagctgatct ggctcagctg gttggctatt
     3661 tcgtcaaccc agttgttctg cgagccaatc tttccggaaa cccaacattt aaggtatttc
     3721 ttgacaaagt acgctcttgt gtgatagatg ccttagctca ccaagattac cccttcccac
     3781 ggttggtcga gcaactacac ctgacccgcg accccagtcg atccccactc ttccaagtga
     3841 tgtttgtctt gcagaaagag cacctcctag aagaaggctt ggcagccttt gccttagggg
     3901 aaacaggagt aaaaataaaa ctaggggagc tagagttgga gtccctgagc gtagaaaagc
     3961 gaatcgctca gttcgatctc actttaatga tggcggaggt cgatggagcc ttgtctgctt
     4021 cttggcaata caacacagac ctgtttgatg ctgctacaat tactcgaacg gcaaagcatt
     4081 ttcagacctt gctcgaaggt atagtcactg acccaaagaa gctggtctca gatttgctac
     4141 tcctgactga ctctgaacag ctgcaactac tgcaagagtg gaatgctacc tttgcagatt
     4201 atagtagtaa ttattgtctt catcaactgt ttgaaaccca agtagagcag acaccagacg
     4261 cagtggcagt ggtgtttgta gaagaacaac tcacctacca agaactgaac caacgggcaa
     4321 atcagttagc acaccatcta caagttttgg gagtgaagcc agaagtgttg gttggcattt
     4381 acctagagcg atcgccagag atgatagtga gtctactagg agttcttaag gcaggcgcgg
     4441 cttacgtccc tctagatcct acctatccta atgagcgttt ggcttttatg ctagaaaatg
     4501 cccaggtttc agtgttgttg actcaagaga agtttgttga aagattacct gaacataagg
     4561 caagggtggt ctgtctggac aaagacgctg aggttttaca tcaccagagt atcgacaacc
     4621 cagttggcaa tgtaacagcc aacaatctgg cttacgtgat ctacacttct ggctcgactg
     4681 gcaagcccaa aggggtcatg aatacccata gagggatctg caaccgttta ttctggatgc
     4741 aggagaccta ccaactgaca acactagatc gggtgttgca gaaaaccccc tttagctttg
     4801 acgtctcgat ttgggaattc ttctggcccc tgatgacggg agcaagtctg gtagtagcac
     4861 gaccaggagg tcatcaagat agttcctact tagtcaaact catacaacag cagcaaatca
     4921 ccacacttca ttttgtcccc tcgatgctgc aagtgtttct ggaggaaccg gatattgaga
     4981 catgtaactg cctgaggaag gtcatgtgca gtggggaagt actacctttt caactccaag
     5041 agcgcttctt tacttatttg gatgcagaac ttcacaatct ttatggacca accgaagcag
     5101 ccattgatgt gaccttttgg gcttgtgagc gagaaagtca tcgacacatc gtccccattg
     5161 gtcgccccat tgccaacacg cagatttatc tgctggacgc tcagttgcag caggttccta
     5221 ttggtgtgcc gggggagctg cacatcagtg gtgcaggtct agcgcggggt tatctcaacc
     5281 aaccagagat gactgctgaa aagttcattc ctaacccttt cagcgatgaa cctggggcac
     5341 gcctgtacaa aactggggac ttggcacgct atctacaagg cagtattatt gagtaccttg
     5401 gtcgcatcga tcaccaagtg aaaattcggg gttgccgcat cgagttggga gagattgagg
     5461 caatattgca ccaacacccc actgtgatag aagcgatcgt cctcagtcga gagactgagt
     5521 ttgtagcaaa accctcttgg gagaatcgag ttattgaccc ggccatcact gagttacgcc
     5581 agttcctcaa gggaaattta cctgaggctg agccgactaa caagcgatta gttgcttact
     5641 gcgtcacacg tcagcaacct acacctacaa cgacagatct gcgtcgcttt ctgaagcaga
     5701 agttgcctga ttacatgatc ccttcgagca tcgtcatcct gaattcactg ccgttgatgc
     5761 ccaacggcaa ggtggatcgg caatcacttc cagatccttt tgatgcacga ccagacctag
     5821 aaacagtgtt tgtagctccc cgcaccccgg tagaagatgc tttagccaag atctgggcac
     5881 aagttcttga gattgaacaa gtaggtatcc atgacaactt cttcgagtta ggaggggatt
     5941 ccattcgtag catccaagta cgggctcaag ctcaagtaag aggcttgagc ttctcgctcc
     6001 agcaaatctt ccagcatcag acaatctaca aactggcgca agaacttagt attactgaac
     6061 ccagttcatt atcgacaccg aaaatagagg agtttgcact gatctctcaa caggatcaac
     6121 agaagttacc tagcagcgtg gaagacgcct atccccttgc cagaagccag gctggactga
     6181 tcttccacac tcagagcagt actgactcct ctatttacca cgacatcttt ctttaccatc
     6241 tgcgaatcca tctagacctt cacatatttc aaaaggttgt gcaggagctt gttgatcggc
     6301 ataccatact gcgtacttcc tttgatctca ccaactttac tgaaccgttg caattagttc
     6361 ataaaacagt tagtgtttca gtacaggtgg aagattttcg ctctttgtct ggtgagcaac
     6421 aaacagaagc acaaaagact tggatagaaa cagaaaaaag ccgacacttt gactggactc
     6481 gtcctccact cgtacgcttt tgtattcatc gcctcgacaa tgagagtttt tacctcgttc
     6541 tgagctttta tgatgctatt cttgatggat ggagtacagc ttccttactc acggaattgc
     6601 ttcaccgcta ttgccagctg cttgatcgag aagagtctcc tatcgagcca ccaccaactg
     6661 taaagtatcg agactttgtg gctttagagc aaaagaatat tgagtcg
//
