LOCUS       c00395_3300009..        3487 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300009709.a:Ga0116227_10056782.
ACCESSION   c00395_3300009..
VERSION     c00395_3300009..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 08:49:43
            Original ID  :: 3300009709.a:Ga0116227_10056782
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 3487
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..3487
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2:3260](+)"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3..3260
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
     cand_cluster    1..3487
                     /SMILES="NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /kind="single"
                     /product="NRPS-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..3487
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS-like"
                     /region_number="1"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX))"
                     /tool="antismash"
     CDS             3..3260
                     /NRPS_PKS="Domain: AMP-binding (222-619). E-value:
                     2.6e-100. Score: 327.6. Matches aSDomain:
                     nrpspksdomains_ctg395_1_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (727-795). E-value: 1.2e-23. Score:
                     74.9. Matches aSDomain: nrpspksdomains_ctg395_1_PCP.1"
                     /NRPS_PKS="Domain: Thioesterase (821-1071). E-value:
                     4.2e-39. Score: 127.0. Matches aSDomain:
                     nrpspksdomains_ctg395_1_Thioesterase.1"
                     /NRPS_PKS="type: NRPS-like protein"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     318.9; E-value: 8.2e-97)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg395_1"
                     /sec_met_domain="AMP-binding (E-value: 5e-105, bitscore:
                     337.4, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 3.1e-18, bitscore:
                     52.4, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 1.9e-10, bitscore:
                     27.8, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="HITYACSKGMIEKWAWFHIEVEGGTLIKRIDDIDPHNLNSSMKLW
                     CIDYGSFGIALIEGIDRTEKSQVTLFTELHQDHSIQHVAYETKNLEQFQDRLTKYNCNI
                     LGEPITKRDAWGIIKQLFCRGYSPTNTAKTTFAEYVQRPRNSTSDSKVTFSQQAGKGFY
                     NQIEVATLQEKYQPFTDFSLMPENWEPPKISESLQLENQCVQSQSNQNGYEQNLLIHQL
                     FEAQVERFPEKMAVVFGASHLTYQALNSRANQLAHYLRSVGVGSEVRVGLCVQPSLELA
                     VGLLGILKAGGVYVPLDPSYPQERLTLMFGQSQIAVLLTQQQLIANLPPYTGPSICLDS
                     DCELFASLEDTNLVNQVSSHHAAYVVHTSGTTGYPKGVVAEHGNFRNYLLATQQRFQFD
                     HQDVFPCIARFSFSISLFELLSPLIVGGKAVIFTRDDVLDIAYLVSQLEHLTNLHSTPS
                     LMRQIVNFIQENHLAAIKYNLRRVFIGGDSIPLNLIEEMKTVFKGAEIYVLYGCSEVTT
                     LCLTYKVPTDTKFEKRIVGKPLNNVSVRLYNEQQLVPVGGKGEIYIGGYGVTRGYLNQP
                     EMTAQKFVTIDNQRFCKTGDWGRSLPDGNIEFIGRADFQIKLRGIRIELGEIEAALVQH
                     PQVQEVVVVASNDIGDERQLIAYVVTTTATTASELRTYLRAKLPLEMIPKVFVGMDNLP
                     LNPNGKLDRRSLPAPTDAIRLPESISLAPRDEVEIQLANIWEKVLGIQPIGVQDNYFDL
                     GGNSLQALRLFAQIERKFGKQLPLSTLLKSATVEALANIVRQPETPVVLSEDDASWSSL
                     VPIQPNGDKPPLFCIHGAGGNILSYRELFVHLDPNLPVYALQAKGLDGKEPLHTRVEDM
                     ASDYIKQIQTIQPAGPYFLGGYSFGGIVAYEIAQQLHQQGEKIGLLFVIDTSAPNAERR
                     LPFSQRIHLHRDKLFHEGLTYLRHKLKGWTRWQTQMFNYKLQKIATNFHLRFGLTLPRD
                     LHNLQMGEASAQASAAYMMQAYPGKLTLFLVDEEMRVEGEGFDHDPNLGWDKLISSGLD
                     IHFVPGDHYSLLNAPHVQVLAEKLQACLDDAIAASLQ"
     aSDomain        669..1859
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg395_1_AMP-binding.1"
                     /evalue="2.60E-100"
                     /label="ctg395_1_AMP-binding.1"
                     /locus_tag="ctg395_1"
                     /protein_end="619"
                     /protein_start="222"
                     /score="327.6"
                     /specificity="consensus: X"
                     /tool="antismash"
                     /translation="FEAQVERFPEKMAVVFGASHLTYQALNSRANQLAHYLRSVGVGSE
                     VRVGLCVQPSLELAVGLLGILKAGGVYVPLDPSYPQERLTLMFGQSQIAVLLTQQQLIA
                     NLPPYTGPSICLDSDCELFASLEDTNLVNQVSSHHAAYVVHTSGTTGYPKGVVAEHGNF
                     RNYLLATQQRFQFDHQDVFPCIARFSFSISLFELLSPLIVGGKAVIFTRDDVLDIAYLV
                     SQLEHLTNLHSTPSLMRQIVNFIQENHLAAIKYNLRRVFIGGDSIPLNLIEEMKTVFKG
                     AEIYVLYGCSEVTTLCLTYKVPTDTKFEKRIVGKPLNNVSVRLYNEQQLVPVGGKGEIY
                     IGGYGVTRGYLNQPEMTAQKFVTIDNQRFCKTGDWGRSLPDGNIEFIGRADFQIKLRG"
     aSModule        669..3215
                     /complete
                     /domains="nrpspksdomains_ctg395_1_AMP-binding.1"
                     /domains="nrpspksdomains_ctg395_1_PCP.1"
                     /domains="nrpspksdomains_ctg395_1_Thioesterase.1"
                     /final_module
                     /locus_tags="ctg395_1"
                     /monomer_pairings="X -> X"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       855..896
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg395_1_0001"
                     /evalue="1.00E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg395_1"
                     /protein_end="298"
                     /protein_start="284"
                     /score="18.6"
                     /tool="antismash"
                     /translation="LGILKAGGVYVPLDP"
     CDS_motif       1089..1148
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg395_1_0002"
                     /evalue="2.80E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg395_1"
                     /protein_end="382"
                     /protein_start="362"
                     /score="23.0"
                     /tool="antismash"
                     /translation="AYVVHTSGTTGYPKGVVAEHG"
     CDS_motif       1662..1751
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg395_1_0003"
                     /evalue="5.30E-14"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg395_1"
                     /protein_end="583"
                     /protein_start="553"
                     /score="44.3"
                     /tool="antismash"
                     /translation="PVGGKGEIYIGGYGVTRGYLNQPEMTAQKFV"
     CDS_motif       1824..1889
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg395_1_0004"
                     /evalue="8.80E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg395_1"
                     /protein_end="629"
                     /protein_start="607"
                     /score="33.8"
                     /tool="antismash"
                     /translation="FIGRADFQIKLRGIRIELGEIEA"
     CDS_motif       1971..2003
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg395_1_0005"
                     /evalue="5.00E+01"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg395_1"
                     /protein_end="667"
                     /protein_start="656"
                     /score="-2.1"
                     /tool="antismash"
                     /translation="AYVVTTTATTAS"
     aSDomain        2184..2387
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg395_1_PCP.1"
                     /evalue="1.20E-23"
                     /label="ctg395_1_PCP.1"
                     /locus_tag="ctg395_1"
                     /protein_end="795"
                     /protein_start="727"
                     /score="74.9"
                     /tool="antismash"
                     /translation="EIQLANIWEKVLGIQPIGVQDNYFDLGGNSLQALRLFAQIERKFG
                     KQLPLSTLLKSATVEALANIVRQP"
     aSDomain        2466..3215
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg395_1_Thioesterase.1"
                     /evalue="4.20E-39"
                     /label="ctg395_1_Thioesterase.1"
                     /locus_tag="ctg395_1"
                     /protein_end="1071"
                     /protein_start="821"
                     /score="127.0"
                     /tool="antismash"
                     /translation="PPLFCIHGAGGNILSYRELFVHLDPNLPVYALQAKGLDGKEPLHT
                     RVEDMASDYIKQIQTIQPAGPYFLGGYSFGGIVAYEIAQQLHQQGEKIGLLFVIDTSAP
                     NAERRLPFSQRIHLHRDKLFHEGLTYLRHKLKGWTRWQTQMFNYKLQKIATNFHLRFGL
                     TLPRDLHNLQMGEASAQASAAYMMQAYPGKLTLFLVDEEMRVEGEGFDHDPNLGWDKLI
                     SSGLDIHFVPGDHYSLLNAPHVQVLAEKL"
     CDS_motif       2469..2498
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg395_1_0006"
                     /evalue="3.00E-03"
                     /label="NRPS-beforete1"
                     /locus_tag="ctg395_1"
                     /protein_end="832"
                     /protein_start="822"
                     /score="10.6"
                     /tool="antismash"
                     /translation="PLFCIHGAGGN"
     CDS_motif       2649..2723
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg395_1_0007"
                     /evalue="1.30E-14"
                     /label="NRPS-te1"
                     /locus_tag="ctg395_1"
                     /protein_end="907"
                     /protein_start="882"
                     /score="46.3"
                     /tool="antismash"
                     /translation="QPAGPYFLGGYSFGGIVAYEIAQQLH"
ORIGIN
        1 atcacataac ttatgcttgc tcgaagggaa tgattgaaaa atgggcatgg ttccacatag
       61 aggttgaagg tggaacattg atcaaacgaa tcgatgatat cgatcctcat aatcttaata
      121 gcagtatgaa actctggtgc attgattatg gttcgtttgg aattgcttta attgaaggaa
      181 tagaccgaac agaaaaatct caagtcactc tgtttacaga actccatcaa gaccatagta
      241 ttcaacacgt tgcttacgag acaaaaaacc tagaacaatt tcaggataga ctcacaaagt
      301 ataactgtaa tattttagga gagccaatta ctaaaaggga tgcatgggga ataatcaagc
      361 agctattttg tagaggttac tctcccacaa acacagcaaa aacaacattt gcagaatatg
      421 tacagagacc acgaaatagc acatcagata gtaaagttac cttctctcag caagcaggaa
      481 aaggttttta caatcagata gaagtcgcta ctctacaaga gaaatatcaa ccatttaccg
      541 acttttctct aatgccagaa aattgggaac ctcctaaaat tagcgaatct cttcaattgg
      601 aaaaccaatg cgttcagtct cagagcaatc aaaatggata cgagcagaac ctactaattc
      661 atcagttgtt tgaggcgcaa gtagaaagat ttccagagaa aatggcagta gtttttggcg
      721 caagccactt aacttatcaa gcactaaata gccgtgctaa tcagctagcg cattacttac
      781 gtagtgtggg tgttggttcg gaggtgagag taggtctatg cgttcagcct tctttggagt
      841 tagcagtagg actgctaggt atcttgaagg cgggaggggt ctacgtcccc ttagatccct
      901 cgtacccgca agaacgcttg actctgatgt tcggtcaatc ccaaatcgca gtgctattaa
      961 cgcagcagca attgatcgct aacttaccac cctacactgg accctccatc tgtttagatt
     1021 ctgattgcga gttatttgcc agcctggaag atactaattt ggttaatcaa gtaagttccc
     1081 accacgcggc ttatgttgtc catacatcag gaaccacagg atatcccaaa ggagttgttg
     1141 ccgaacatgg caatttcagg aactatcttt tagctacgca acagcgattc cagtttgacc
     1201 atcaagatgt gttcccctgc attgcgcggt tctcttttag catctcttta tttgaattac
     1261 tgagcccttt aattgttggc ggtaaagctg taattttcac tagagatgat gtcttagata
     1321 ttgcttatct agtcagtcaa ctagagcact tgactaatct tcattctact ccaagtttga
     1381 tgcggcaaat cgtcaatttt atccaagaga atcatttagc tgccattaaa tacaatctca
     1441 gaagagtatt tatcggcggt gattcaattc ctctcaactt gattgaggag atgaaaaccg
     1501 tattcaaagg ggctgagata tatgtcctct atggatgcag tgaagtgaca actttatgct
     1561 tgacttataa agttcccacc gacacaaagt ttgaaaaacg cattgttggc aaaccactta
     1621 ataatgtttc cgtacgcttg tataacgaac agcaattagt gcccgttggt ggcaagggtg
     1681 aaatttatat cggtggatac ggagtcacgc ggggatacct aaatcaacca gagatgaccg
     1741 cacaaaagtt tgtcaccatt gataatcaac gcttttgcaa aacgggggat tggggacggt
     1801 ctctgcccga tggtaatatt gaattcatcg gtcgtgcaga ctttcaaatt aaacttcgcg
     1861 gcattcggat tgaactcgga gaaattgaag ctgctttagt ccaacatccc caagtccaag
     1921 aggttgtggt tgtcgctagc aatgacatag gtgatgaacg gcagttaatc gcctatgttg
     1981 tgacaacaac cgcaacaaca gcaagcgaac tgcggactta tttacgtgcc aagctaccgc
     2041 tggaaatgat cccaaaagtg tttgtcggga tggataactt gcccctcaac ccgaatggca
     2101 agctggatcg gcggtcatta cccgcaccca ccgacgctat acggctacca gaatcaattt
     2161 ctctggcccc acgggatgaa gtggagatcc aactggcaaa tatttgggaa aaagttctcg
     2221 gtatccaacc cattggcgtg caggataatt acttcgatct cggcggtaac tctctgcaag
     2281 ccttacgtct atttgcccaa attgagcgca aatttggcaa acagctacct ctgagtactc
     2341 tcttaaaatc agcaactgta gaggctcttg ctaatattgt ccgccagcca gaaaccccag
     2401 ttgtcttgtc agaggatgat gcgtcttggt catcactagt accgattcaa cctaatggtg
     2461 acaaaccacc tttgttctgt atacatgggg ctggcggaaa tatcctttcc taccgcgagc
     2521 tttttgttca tctcgatccc aatcttccag tgtatgctct tcaagctaaa ggattggatg
     2581 gaaaagagcc tctccatacc cgagttgaag acatggcatc tgactacatc aaacagatcc
     2641 aaaccatcca acctgcagga ccttattttc tgggaggcta ctcctttggc ggtatagtgg
     2701 cttacgaaat agcccagcaa ctgcatcagc aaggggagaa aatcggtctg ctatttgtga
     2761 tcgatacctc tgcacctaat gctgagcggc gattgccttt cagtcagcga atacaccttc
     2821 atcgtgataa gctcttccac gaaggactta cctatctccg tcacaagctg aagggatgga
     2881 ccagatggca gacgcagatg ttcaattaca agttacagaa gatcgccacc aactttcatt
     2941 tgcgttttgg tttgacatta cctcgcgatc ttcataactt acagatggga gaggctagcg
     3001 cacaggcttc agcagcatat atgatgcaag cttaccccgg taaactaact ctgtttctag
     3061 ttgacgagga aatgcgggta gaaggtgaag gctttgatca cgatcctaat ttaggctggg
     3121 ataaactgat tagttcgggg ttagatatcc atttcgttcc tggggatcac tattctttgc
     3181 tcaacgcacc ccacgtacaa gtgctagctg aaaaattaca ggcttgttta gacgacgcta
     3241 ttgcagctag cttacaatag acccggtaat caatactgct cggttaagaa atttcagttc
     3301 ggaatctggg ttagggaaaa ggttactggg tttggggtaa aggacttttc tttccccttc
     3361 ccctttcccc tttcccccaa aacctgtgca gtattgaccc ggtaatgggt gttgagtatc
     3421 tgacttttcc cgttaagtcg tgaaacctag aaatgataag ggttttggag tgtagtttga
     3481 ttctcaa
//
