LOCUS       c00454_3300009..       12867 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300009709.a:Ga0116227_10013439.
ACCESSION   c00454_3300009..
VERSION     c00454_3300009..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 08:49:43
            Original ID  :: 3300009709.a:Ga0116227_10013439
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12867
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12867
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1167:5262](-)"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(1168..5262)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     protocluster    1..12867
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[5769:10416](-)"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      complement(5770..10416)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="2"
     cand_cluster    1..12867
                     /SMILES="CC(O)NCCC(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /detection_rules="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /kind="neighbouring"
                     /product="T1PKS"
                     /product="NRPS"
                     /protoclusters="2"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12867
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T1PKS"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /rules="(cds(Condensation and (AMP-binding or A-OX)) or
                     (Condensation and AMP-binding))"
                     /tool="antismash"
     CDS             complement(3..1145)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034:cytochrome P450 (Score: 269.5; E-value: 9.6e-82)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg454_1"
                     /sec_met_domain="p450 (E-value: 2.4e-60, bitscore: 192.9,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLPAGPKTATWLLNHQFQADPFGYMDAVYKRYGDIVTIMSGSTP
                     TVHISNPLGIKQVFTNTKEITARGALNQSFALMTGNQGVLQLDGFRHKHRRKLLMQAFH
                     GERMQACGQRICELTEKIISQQAIGKLFIAYPTIEDITLRVGIEVVMGLREGERYDKIK
                     HLFASTIKHSQSPFYKFVINLPFGQRDLGRWSPWGYRLHLRQELLQLLDSEVKERRVQA
                     DPSRRDILSDLIFASDETGEPLSDEEVRDLLLSPIFAAQDASATAIAWSLYWIHRLPDV
                     RSRLVEELDSLGESPDPMSIVALPYLNAVCNEALRIYPTQLFTFPRLVESPIEVMGYEL
                     SPGTVLIGSIYLTHQREDLYPEPKQFKPERFLEKQFSPYEF"
     CDS             complement(1168..5262)
                     /NRPS_PKS="Domain: Condensation_LCL (36-336). E-value:
                     6.3e-116. Score: 378.3. Matches aSDomain:
                     nrpspksdomains_ctg454_2_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (501-903). E-value:
                     3.7e-115. Score: 376.5. Matches aSDomain:
                     nrpspksdomains_ctg454_2_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (1013-1079). E-value: 2.2e-22.
                     Score: 70.8. Matches aSDomain:
                     nrpspksdomains_ctg454_2_PCP.1"
                     /NRPS_PKS="Domain: Thioesterase (1099-1341). E-value:
                     7.9e-36. Score: 116.3. Matches aSDomain:
                     nrpspksdomains_ctg454_2_Thioesterase.1"
                     /NRPS_PKS="type: NRPS"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     448.3; E-value: 5.7e-136)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg454_2"
                     /sec_met_domain="Condensation (E-value: 6.8e-81, bitscore:
                     260.0, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 1.8e-126, bitscore:
                     410.4, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 9.4e-17, bitscore:
                     49.9, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKQHSNLSPAKKALLEKWKGGKFKADTIPGRQASHNTPLSFSQQ
                     RLWFIDQLYHGSSFYNIPSASHLMGSLNITALQQSLNEILRRHEVWRTTFALVNGEPVQ
                     EIAPEFTWDLPIINFEHLFGKDWEPEVKQLAAEEAKKPFNLAKGPLVRATLLRLGEEEH
                     VFLLTMHHIITDGWSIGVFMRELATLYTAFSTNQPSPLPELPIQYADFAVWQRDRLQGE
                     LLKTQLNYWKQQLSGDLPVLQLPTDRLRPTVTTFTGAKQYFTFSKTLTDALNQFSQRED
                     ATLFMTLLAAFNLLLYHYTDQEDILIGSPIANRNRAELEGMLGLFVNTLVLRNNLSGDP
                     SFRELLHRVREVTLDAYAHQDLPFEMLVEELQPERDLSRNPLYEVMFILQNTPTSVQEA
                     SSLTVRTLQFDSGTAQLDIFLSMSESQQGLTGFLEYNTDIFEDAKITRLITHFQALLES
                     IVANPEQRICELSPLTVPEREQLLFEWNQTNADYSQDTSLHQLFEQQVEQFPDALALIS
                     QSEELTYRQLNQRVNQLAHYLQKHGVTKETLVAICLERSPEMVVGILAVLKAGGAYIPL
                     DPSYPVERLGFMLSDSQASVLITQQEILEKLSTSSAKTVYLDMHFNEIARESEENLISL
                     SKADNLAYVIYTSGSTGTPKGVLGTHGGTVNGLHWFWKTYPFTKEEVCCQKTAISFVDS
                     VWEIFAPLLQGIPTAIIPDAIVKDPQLFVETLAHYKVTRIVLVPSLLRLLLDSYSHLTK
                     NLSHLKLWITSGEALSVNLAQTFRELMPSAKLINLYGSSEVSANVTYYDSSLLPHQPNS
                     VPIGRPIDNTLVYVLNRHLQLTPVGVIGELYIGGDGLARGYLHHPELTQEKFIDNPFVP
                     GTKLYKTGDLARYLNDGNLEYLGRRDDQVKIRGFRVELGEIAYAIAQHPDVQESVVIVQ
                     DDTQGDQRLIAYVVTDKQEVVPHLTSYLQDKLPNYMIPSAFVVLDAIPLTPNGKVDKRS
                     LPTDDRIRPNATQSFVAPRNFTELSLGKTWENLLNINPIGVTDNFFDLGGHSFLAVRLM
                     AQIHDRFGHNLPLSTLFENPTIEKLATIVSQPVHESSNSHLVAIQSNGSKVPFFCMHGA
                     GGGVNAYFKLSRRLGEDYPFYALQDPSSQEDPEIISVEETASRYLQEIRQVQPNGPYFL
                     GGFCYGGVIAFEMAQQLQRQGQTVGLLLVIDTIIPETAIKPAEDDDAKFLLRMAEAIKT
                     NSKIDFSIPFEELRDLPINEQFHLVNKKANFIFSDTEIKDFLRYYKLFKAHVQAMRDYV
                     PQAYPHSMTLFRANEEIIHDFENPEFHTDDPLLGWGKFSSHPIQVIEVPGDHFSIFIEP
                     NIQELAKQLRICIDNALYRVA"
     aSDomain        complement(1240..1965)
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg454_2_Thioesterase.1"
                     /evalue="7.90E-36"
                     /label="ctg454_2_Thioesterase.1"
                     /locus_tag="ctg454_2"
                     /protein_end="1341"
                     /protein_start="1099"
                     /score="116.3"
                     /tool="antismash"
                     /translation="PFFCMHGAGGGVNAYFKLSRRLGEDYPFYALQDPSSQEDPEIISV
                     EETASRYLQEIRQVQPNGPYFLGGFCYGGVIAFEMAQQLQRQGQTVGLLLVIDTIIPET
                     AIKPAEDDDAKFLLRMAEAIKTNSKIDFSIPFEELRDLPINEQFHLVNKKANFIFSDTE
                     IKDFLRYYKLFKAHVQAMRDYVPQAYPHSMTLFRANEEIIHDFENPEFHTDDPLLGWGK
                     FSSHPIQVIEVPGDHFSIFIE"
     aSModule        1240..5154
                     /complete
                     /domains="nrpspksdomains_ctg454_2_Condensation_LCL.1"
                     /domains="nrpspksdomains_ctg454_2_AMP-binding.1"
                     /domains="nrpspksdomains_ctg454_2_PCP.1"
                     /domains="nrpspksdomains_ctg454_2_Thioesterase.1"
                     /final_module
                     /locus_tags="ctg454_2"
                     /monomer_pairings="ala-b -> ala-b"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(1714..1788)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg454_2_0010"
                     /evalue="3.30E-13"
                     /label="NRPS-te1"
                     /locus_tag="ctg454_2"
                     /protein_end="1183"
                     /protein_start="1158"
                     /score="41.9"
                     /tool="antismash"
                     /translation="QPNGPYFLGGFCYGGVIAFEMAQQLQ"
     aSDomain        complement(2026..2223)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg454_2_PCP.1"
                     /evalue="2.20E-22"
                     /label="ctg454_2_PCP.1"
                     /locus_tag="ctg454_2"
                     /protein_end="1079"
                     /protein_start="1013"
                     /score="70.8"
                     /tool="antismash"
                     /translation="SLGKTWENLLNINPIGVTDNFFDLGGHSFLAVRLMAQIHDRFGHN
                     LPLSTLFENPTIEKLATIVSQP"
     CDS_motif       complement(2527..2589)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg454_2_0009"
                     /evalue="3.80E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg454_2"
                     /protein_end="912"
                     /protein_start="891"
                     /score="38.1"
                     /tool="antismash"
                     /translation="YLGRRDDQVKIRGFRVELGEIA"
     aSDomain        complement(2554..3759)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg454_2_AMP-binding.1"
                     /evalue="3.70E-115"
                     /label="ctg454_2_AMP-binding.1"
                     /locus_tag="ctg454_2"
                     /protein_end="903"
                     /protein_start="501"
                     /score="376.5"
                     /specificity="consensus: ala-b"
                     /tool="antismash"
                     /translation="FEQQVEQFPDALALISQSEELTYRQLNQRVNQLAHYLQKHGVTKE
                     TLVAICLERSPEMVVGILAVLKAGGAYIPLDPSYPVERLGFMLSDSQASVLITQQEILE
                     KLSTSSAKTVYLDMHFNEIARESEENLISLSKADNLAYVIYTSGSTGTPKGVLGTHGGT
                     VNGLHWFWKTYPFTKEEVCCQKTAISFVDSVWEIFAPLLQGIPTAIIPDAIVKDPQLFV
                     ETLAHYKVTRIVLVPSLLRLLLDSYSHLTKNLSHLKLWITSGEALSVNLAQTFRELMPS
                     AKLINLYGSSEVSANVTYYDSSLLPHQPNSVPIGRPIDNTLVYVLNRHLQLTPVGVIGE
                     LYIGGDGLARGYLHHPELTQEKFIDNPFVPGTKLYKTGDLARYLNDGNLEYLGRRDDQV
                     KIRG"
     CDS_motif       complement(2671..2760)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg454_2_0008"
                     /evalue="9.30E-18"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg454_2"
                     /protein_end="864"
                     /protein_start="834"
                     /score="56.3"
                     /tool="antismash"
                     /translation="PVGVIGELYIGGDGLARGYLHHPELTQEKFI"
     CDS_motif       complement(3280..3339)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg454_2_0007"
                     /evalue="1.40E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg454_2"
                     /protein_end="661"
                     /protein_start="641"
                     /score="29.9"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGTPKGVLGTHG"
     CDS_motif       complement(3532..3573)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg454_2_0006"
                     /evalue="1.90E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg454_2"
                     /protein_end="577"
                     /protein_start="563"
                     /score="17.8"
                     /tool="antismash"
                     /translation="LAVLKAGGAYIPLDP"
     CDS_motif       complement(4096..4215)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg454_2_0005"
                     /evalue="4.90E-25"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="ctg454_2"
                     /protein_end="389"
                     /protein_start="349"
                     /score="80.1"
                     /tool="antismash"
                     /translation="REVTLDAYAHQDLPFEMLVEELQPERDLSRNPLYEVMFILQ"
     aSDomain        complement(4255..5154)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg454_2_Condensation_LCL.1"
                     /domain_subtype="Condensation_LCL"
                     /evalue="6.30E-116"
                     /label="ctg454_2_Condensation_LCL.1"
                     /locus_tag="ctg454_2"
                     /protein_end="336"
                     /protein_start="36"
                     /score="378.3"
                     /tool="antismash"
                     /translation="NTPLSFSQQRLWFIDQLYHGSSFYNIPSASHLMGSLNITALQQSL
                     NEILRRHEVWRTTFALVNGEPVQEIAPEFTWDLPIINFEHLFGKDWEPEVKQLAAEEAK
                     KPFNLAKGPLVRATLLRLGEEEHVFLLTMHHIITDGWSIGVFMRELATLYTAFSTNQPS
                     PLPELPIQYADFAVWQRDRLQGELLKTQLNYWKQQLSGDLPVLQLPTDRLRPTVTTFTG
                     AKQYFTFSKTLTDALNQFSQREDATLFMTLLAAFNLLLYHYTDQEDILIGSPIANRNRA
                     ELEGMLGLFVNTLVLRNNLS"
     CDS_motif       complement(4264..4353)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg454_2_0004"
                     /evalue="1.60E-17"
                     /label="C5_LCL_267-296"
                     /locus_tag="ctg454_2"
                     /protein_end="333"
                     /protein_start="303"
                     /score="55.7"
                     /tool="antismash"
                     /translation="DILIGSPIANRNRAELEGMLGLFVNTLVLRN"
     CDS_motif       complement(4606..4644)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg454_2_0003"
                     /evalue="5.00E-06"
                     /label="C4_LCL_164-176"
                     /locus_tag="ctg454_2"
                     /protein_end="219"
                     /protein_start="206"
                     /score="18.9"
                     /tool="antismash"
                     /translation="QYADFAVWQRDRLQ"
     CDS_motif       complement(4693..4758)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg454_2_0002"
                     /evalue="3.40E-13"
                     /label="C3_LCL_132-143"
                     /locus_tag="ctg454_2"
                     /protein_end="190"
                     /protein_start="168"
                     /score="41.9"
                     /tool="antismash"
                     /translation="MHHIITDGWSIGVFMRELATLYT"
     CDS_motif       complement(4975..5088)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg454_2_0001"
                     /evalue="4.50E-12"
                     /label="C2_LCL_024-062"
                     /locus_tag="ctg454_2"
                     /protein_end="96"
                     /protein_start="58"
                     /score="38.3"
                     /tool="antismash"
                     /translation="FYNIPSASHLMGSLNITALQQSLNEILRRHEVWRTTFAL"
     CDS             complement(5315..5689)
                     /locus_tag="ctg454_3"
                     /transl_table=11
                     /translation="MECFLPGLAHDGSKPTDSFVTKNMRRSARRAVSQCGLGVSPSRAT
                     DVSEAIARNERRTRASPEGREKLFSSLFESHVFKRGIIAAFCPLPSAFLLLSWRSSRLQ
                     PFGHALRVGGASRREGGSLK"
     CDS             complement(5770..10416)
                     /NRPS_PKS="Domain: PKS_KS(Hybrid-KS) (12-438). E-value:
                     5.5e-163. Score: 534.5. Matches aSDomain:
                     nrpspksdomains_ctg454_4_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (535-837). E-value: 2e-106.
                     Score: 347.4. Matches aSDomain:
                     nrpspksdomains_ctg454_4_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_KR (1166-1361). E-value: 1.4e-23.
                     Score: 75.5. Matches aSDomain:
                     nrpspksdomains_ctg454_4_PKS_KR.1"
                     /NRPS_PKS="Domain: PCP (1455-1524). E-value: 3e-23. Score:
                     73.6. Matches aSDomain: nrpspksdomains_ctg454_4_PCP.1"
                     /NRPS_PKS="type: PKS-like protein"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     hyb_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 246.4; E-value:
                     9.2e-75)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg454_4"
                     /sec_met_domain="PP-binding (E-value: 7.2e-15, bitscore:
                     43.8, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 2e-107, bitscore: 347.4,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="hyb_KS (E-value: 9.5e-169, bitscore:
                     550.1, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDNQQIHDAIKGIAVIGMVGRFPKAKGVDEFWQNLCNGQESISFF
                     SNEELEDSGIDPALLSNPNYIKAGARLSDIDLFDAPFFDFSPREAEIMDPQQRIFLECA
                     WEALETAGYAPGSDKRLTGVYAGTNLSVYLLSQFSSNPDLIKSMGSLVELSNGQHHLAT
                     KVSYKLNLKGPSINISTACSTSLVAVHSACQGLLNYECDLALGGGISIQSSQKQGYFYE
                     EGGMTSPDGRCRAFDAKARGTIFGDGVGIVVLKRLEDALDDGDCIHAVIKGSAINNDGA
                     MKVGYTAPSVGGQSKVIVEAQANAGFNPETITYIETHGTGTALGDPIEISALKKTFEAC
                     TKKKGFCAIGSVKPNVGHLNVASGITSLIKTVQALKHKMIPPSLHFEQPNPEIDFANSP
                     FYVNTKLSEWKTNGTPRRAGVSSFGIGGTNAHVILEQAPIVEPSSASRPWQLLLLSAKT
                     STALETTTASLATHLQQYPDLNLADVAHTLQVGRRAFDHRRMVICHDSEDAVKILKSQD
                     VQHVFTYHRKPSHRPVVFMFSGQGAQYVNMARELYSVEPTFGKYVDICADILKPLLNFD
                     IRHILYPDPQHTQTATQQLQQTAITQSALFVIEYALAQLWIEWGVNPEAMIGHSIGEYV
                     AATIAGVFSLEDALAIVSTRGQLMQQLPRGSMLAIPLPEKDVQSLIEDVETFHGTSLQI
                     AAINSPSSCVVSGSSDAIATLQNQLSSQGIDCRLLHTSHAFHSHMMEPILEPFVQVLKK
                     VKLNPPRIRFISNVTGTWITDGQATNPNYWGQHLRQTVKFSDGISQLLQQFEGVFLEVS
                     PGRTLSTLTTQHLKPEAKQIVLTSLAHAQEQQSDVSFLLQTLGRLWLSGVEIDWSGFYT
                     HEQRHRLPLPTYPFERQRYWIDAKSPSSSSSGKPVTLDKKQDIADWFYIPSWKRSLLPG
                     SSSPNQNESAQEQWLLFVDESGVGSQLVNRLEQNGKNVIVVKVGEQFTKLREGIYAIHP
                     QNRDEYDVLFQELIELGKTPQHIAHLWSLNTFGTRQQGEFLEFKSLLFLTQALGKHKIS
                     DRLQVWVVSNQIQEVNGNERLDPEKATVLGLCKVIPQEYANITCRNIDFVLANRQDAKD
                     AEGGTGNCAAHIVDQIISEFTSLSSDLVVAYRDRYRWVQTFEPVRLESAVEEKIPLRKQ
                     GVYLFPGGLESIGVVLAGYLAKTLQAKLIFIEDSAFPGKDEYSQWLETHAQEDEVSRKI
                     QNLVSLEALGAEVLVVRADTTNYEQMHSCLALEKIGQIHGIIYLTGRTRENMFCSIPEI
                     AKTELEKLLDSQNDKITLLEKVLQSRKLDFCIIFSSLSSILGGFGLALYSGVNQLTDTF
                     TQKHNQTNSFPWISINLDKLHLNATQEQKILGQSGMELAITETESVEVFKRIFSLGEAT
                     QVIVSTVDIKARSDRAFKLDSRLYSKSSTQVDSSSRYSRPSLGNSYVAPSNELEKQIAE
                     IWQEVLGIAQVGIYDNFYELGGDSLIATQLVSRLRAKFPVELPLRDFLLQAMIPAKQAE
                     MIEQLLLEKIEELSEEEVAVLLATPFSV"
     aSDomain        complement(5845..6051)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg454_4_PCP.1"
                     /evalue="3.00E-23"
                     /label="ctg454_4_PCP.1"
                     /locus_tag="ctg454_4"
                     /protein_end="1524"
                     /protein_start="1455"
                     /score="73.6"
                     /tool="antismash"
                     /translation="EKQIAEIWQEVLGIAQVGIYDNFYELGGDSLIATQLVSRLRAKFP
                     VELPLRDFLLQAMIPAKQAEMIEQL"
     aSModule        5845..10380
                     /complete
                     /domains="nrpspksdomains_ctg454_4_PKS_KS.1"
                     /domains="nrpspksdomains_ctg454_4_PKS_AT.1"
                     /domains="nrpspksdomains_ctg454_4_PKS_KR.1"
                     /domains="nrpspksdomains_ctg454_4_PCP.1"
                     /locus_tags="ctg454_4"
                     /monomer_pairings="mal -> ohmal"
                     /tool="antismash"
                     /type="pks"
     aSDomain        complement(6334..6918)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg454_4_PKS_KR.1"
                     /evalue="1.40E-23"
                     /label="ctg454_4_PKS_KR.1"
                     /locus_tag="ctg454_4"
                     /protein_end="1361"
                     /protein_start="1166"
                     /score="75.5"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: (unknown)"
                     /tool="antismash"
                     /translation="GVYLFPGGLESIGVVLAGYLAKTLQAKLIFIEDSAFPGKDEYSQW
                     LETHAQEDEVSRKIQNLVSLEALGAEVLVVRADTTNYEQMHSCLALEKIGQIHGIIYLT
                     GRTRENMFCSIPEIAKTELEKLLDSQNDKITLLEKVLQSRKLDFCIIFSSLSSILGGFG
                     LALYSGVNQLTDTFTQKHNQTNSFPWISINLDK"
     CDS_motif       complement(6406..6483)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg454_4_0011"
                     /evalue="1.10E-06"
                     /label="PKSI-KR_m4"
                     /locus_tag="ctg454_4"
                     /protein_end="1337"
                     /protein_start="1311"
                     /score="21.2"
                     /tool="antismash"
                     /translation="LDFCIIFSSLSSILGGFGLALYSGVNQ"
     CDS_motif       complement(6961..6981)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg454_4_0010"
                     /evalue="9.90E+01"
                     /label="PKSI-AT-M_m8"
                     /locus_tag="ctg454_4"
                     /protein_end="1152"
                     /protein_start="1145"
                     /score="-2.7"
                     /tool="antismash"
                     /translation="QTFEPVRL"
     aSDomain        complement(7906..8811)
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg454_4_PKS_AT.1"
                     /evalue="2.00E-106"
                     /label="ctg454_4_PKS_AT.1"
                     /locus_tag="ctg454_4"
                     /protein_end="837"
                     /protein_start="535"
                     /score="347.4"
                     /specificity="consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="MFSGQGAQYVNMARELYSVEPTFGKYVDICADILKPLLNFDIRHI
                     LYPDPQHTQTATQQLQQTAITQSALFVIEYALAQLWIEWGVNPEAMIGHSIGEYVAATI
                     AGVFSLEDALAIVSTRGQLMQQLPRGSMLAIPLPEKDVQSLIEDVETFHGTSLQIAAIN
                     SPSSCVVSGSSDAIATLQNQLSSQGIDCRLLHTSHAFHSHMMEPILEPFVQVLKKVKLN
                     PPRIRFISNVTGTWITDGQATNPNYWGQHLRQTVKFSDGISQLLQQFEGVFLEVSPGRT
                     LSTLTTQHLKPEAKQIVLTSLA"
     CDS_motif       complement(8038..8073)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg454_4_0009"
                     /evalue="1.20E-04"
                     /label="PKSI-AT-M_m8"
                     /locus_tag="ctg454_4"
                     /protein_end="793"
                     /protein_start="781"
                     /score="15.5"
                     /tool="antismash"
                     /translation="YWGQHLRQTVKFS"
     CDS_motif       complement(8110..8142)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg454_4_0008"
                     /evalue="5.90E-03"
                     /label="PKSI-AT-M_m7"
                     /locus_tag="ctg454_4"
                     /protein_end="769"
                     /protein_start="758"
                     /score="9.5"
                     /tool="antismash"
                     /translation="PRIRFISNVTGT"
     CDS_motif       complement(8188..8208)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg454_4_0007"
                     /evalue="8.10E+01"
                     /label="PKSI-AT-M_m8"
                     /locus_tag="ctg454_4"
                     /protein_end="743"
                     /protein_start="736"
                     /score="-2.4"
                     /tool="antismash"
                     /translation="SHMMEPIL"
     CDS_motif       complement(8296..8334)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg454_4_0006"
                     /evalue="9.00E-05"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="ctg454_4"
                     /protein_end="707"
                     /protein_start="694"
                     /score="15.6"
                     /tool="antismash"
                     /translation="AAINSPSSCVVSGS"
     CDS_motif       complement(8437..8559)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg454_4_0005"
                     /evalue="4.10E-26"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="ctg454_4"
                     /protein_end="660"
                     /protein_start="619"
                     /score="83.4"
                     /tool="antismash"
                     /translation="GVNPEAMIGHSIGEYVAATIAGVFSLEDALAIVSTRGQLMQQ"
     CDS_motif       complement(8761..8808)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg454_4_0004"
                     /evalue="2.00E-06"
                     /label="PKSI-AT-M_m1"
                     /locus_tag="ctg454_4"
                     /protein_end="552"
                     /protein_start="536"
                     /score="20.1"
                     /tool="antismash"
                     /translation="FSGQGAQYVNMARELYS"
     aSDomain        complement(9103..10380)
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg454_4_PKS_KS.1"
                     /evalue="5.50E-163"
                     /label="ctg454_4_PKS_KS.1"
                     /locus_tag="ctg454_4"
                     /protein_end="438"
                     /protein_start="12"
                     /score="534.5"
                     /tool="antismash"
                     /translation="IAVIGMVGRFPKAKGVDEFWQNLCNGQESISFFSNEELEDSGIDP
                     ALLSNPNYIKAGARLSDIDLFDAPFFDFSPREAEIMDPQQRIFLECAWEALETAGYAPG
                     SDKRLTGVYAGTNLSVYLLSQFSSNPDLIKSMGSLVELSNGQHHLATKVSYKLNLKGPS
                     INISTACSTSLVAVHSACQGLLNYECDLALGGGISIQSSQKQGYFYEEGGMTSPDGRCR
                     AFDAKARGTIFGDGVGIVVLKRLEDALDDGDCIHAVIKGSAINNDGAMKVGYTAPSVGG
                     QSKVIVEAQANAGFNPETITYIETHGTGTALGDPIEISALKKTFEACTKKKGFCAIGSV
                     KPNVGHLNVASGITSLIKTVQALKHKMIPPSLHFEQPNPEIDFANSPFYVNTKLSEWKT
                     NGTPRRAGVSSFGIGGTNAHVILEQAPI"
     CDS_motif       complement(9430..9477)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg454_4_0003"
                     /evalue="3.40E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="ctg454_4"
                     /protein_end="329"
                     /protein_start="313"
                     /score="12.8"
                     /tool="antismash"
                     /translation="YIETHGTGTALGDPIEI"
     CDS_motif       complement(9676..9708)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg454_4_0002"
                     /evalue="9.90E+01"
                     /label="PKSI-KS_m5"
                     /locus_tag="ctg454_4"
                     /protein_end="247"
                     /protein_start="236"
                     /score="-3.1"
                     /tool="antismash"
                     /translation="DAKARGTIFGDG"
     CDS_motif       complement(9853..9900)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg454_4_0001"
                     /evalue="4.60E-05"
                     /label="PKSI-KS_m3"
                     /locus_tag="ctg454_4"
                     /protein_end="188"
                     /protein_start="172"
                     /score="15.7"
                     /tool="antismash"
                     /translation="GPSINISTACSTSLVAV"
     CDS             complement(10409..12865)
                     /NRPS_PKS="Domain: PKS_KR (421-621). E-value: 3.4e-53.
                     Score: 172.0. Matches aSDomain:
                     nrpspksdomains_ctg454_5_PKS_KR.1"
                     /NRPS_PKS="Domain: PCP (713-780). E-value: 5.7e-24. Score:
                     75.9. Matches aSDomain: nrpspksdomains_ctg454_5_PCP.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PKS_AT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg454_5"
                     /sec_met_domain="PP-binding (E-value: 2.1e-19, bitscore:
                     58.4, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 3.5e-25, bitscore: 77.4,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 6.8e-41, bitscore:
                     128.6, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LEPFVQAVKKVKLNLPRIRFISNVTGTWITDDQATNPNYWGQHLR
                     QTVKFSDGISQLLEQFEGVFLEVGPGRTLSTLTTQHLKPEAKQIVLASLAHAKEQQSDV
                     SYLLQTLGRLWLSGVEIDWSGFYTHEHRHRLPLPTYPFERQRYWIEPKKQGIDERPTPV
                     SLGEKPDIADWFYIPFWKPSSPPVPLNQEKLAEQKSCTLVFIDECGLGTKLVKQLEQQN
                     QDVITVKVGGEFTQISESQYTLNPQQPYDYEALIKELLTQQQLPKTIVHLWSVTPVGDK
                     ELELEEVDLAQAIGFYSLLFLAQALGRKETPDDFQITVISNNLQPVTGTEVLCPEKATL
                     LGPIKVISQEYLNIRCRSIDVILPPTGSWLEEKLVERLVAELTVPTSDQVIAYRGINRW
                     VQSFEPVRFDEAKIGKARLREKGVYLITGGLGGIGQVIAEYLAKTLQAKLLLIGRTALP
                     HRDEWEQWLLTHDETDSTSRKIQKVQQLEQLGAEVLVVSADVSNTEQMQEAIAQAESRF
                     GQLNGVIHAAGIVGGRSFAAIEKISQTDCEQQFQPKVHGLLVLEKVLQDRDIDFCFLLS
                     SLSSVLGGLGFVAYSAANIFMDAFVHQHNQSHPFSWISVSWDGWQLEKENKQSTLVGAR
                     VAEFAFNPKEGVEAFQRILNWCEFNHVVVSTGELKARIDRWIQSESFQQKVDSQQANSL
                     SLHPRPDLQIPYFPLTNEIEQKIANIWQEVIGIKDVGLYDNFFELGGDSLLLIQVRSKL
                     LKTLNKNLSIADLFEYSTINALAEYLGGKQVEEPTFQQADERASRKEAAMQEKRKLMKQ
                     RKKVDG"
     aSDomain        complement(10526..10726)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg454_5_PCP.1"
                     /evalue="5.70E-24"
                     /label="ctg454_5_PCP.1"
                     /locus_tag="ctg454_5"
                     /protein_end="780"
                     /protein_start="713"
                     /score="75.9"
                     /tool="antismash"
                     /translation="EQKIANIWQEVIGIKDVGLYDNFFELGGDSLLLIQVRSKLLKTLN
                     KNLSIADLFEYSTINALAEYLGG"
     aSModule        10526..11602
                     /domains="nrpspksdomains_ctg454_5_PKS_KR.1"
                     /domains="nrpspksdomains_ctg454_5_PCP.1"
                     /incomplete
                     /locus_tags="ctg454_5"
                     /tool="antismash"
                     /type="unknown"
     aSDomain        complement(11003..11602)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg454_5_PKS_KR.1"
                     /evalue="3.40E-53"
                     /label="ctg454_5_PKS_KR.1"
                     /locus_tag="ctg454_5"
                     /protein_end="621"
                     /protein_start="421"
                     /score="172.0"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: (unknown)"
                     /tool="antismash"
                     /translation="GVYLITGGLGGIGQVIAEYLAKTLQAKLLLIGRTALPHRDEWEQW
                     LLTHDETDSTSRKIQKVQQLEQLGAEVLVVSADVSNTEQMQEAIAQAESRFGQLNGVIH
                     AAGIVGGRSFAAIEKISQTDCEQQFQPKVHGLLVLEKVLQDRDIDFCFLLSSLSSVLGG
                     LGFVAYSAANIFMDAFVHQHNQSHPFSWISVSWDGWQL"
     CDS_motif       complement(11057..11158)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg454_5_0006"
                     /evalue="1.30E-12"
                     /label="PKSI-KR_m4"
                     /locus_tag="ctg454_5"
                     /protein_end="603"
                     /protein_start="569"
                     /score="40.3"
                     /tool="antismash"
                     /translation="DFCFLLSSLSSVLGGLGFVAYSAANIFMDAFVHQH"
     CDS_motif       complement(11501..11599)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg454_5_0005"
                     /evalue="2.40E-11"
                     /label="PKSI-KR_m1"
                     /locus_tag="ctg454_5"
                     /protein_end="455"
                     /protein_start="422"
                     /score="36.2"
                     /tool="antismash"
                     /translation="VYLITGGLGGIGQVIAEYLAKTLQAKLLLIGRTA"
     CDS_motif       complement(11642..11665)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg454_5_0004"
                     /evalue="5.90E+00"
                     /label="PKSI-AT-M_m8"
                     /locus_tag="ctg454_5"
                     /protein_end="408"
                     /protein_start="400"
                     /score="1.1"
                     /tool="antismash"
                     /translation="QSFEPVRFD"
     CDS_motif       complement(11900..11920)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg454_5_0003"
                     /evalue="5.60E+01"
                     /label="PKSI-AT-M_m7"
                     /locus_tag="ctg454_5"
                     /protein_end="322"
                     /protein_start="315"
                     /score="-1.9"
                     /tool="antismash"
                     /translation="QITVISNN"
     CDS_motif       complement(12716..12751)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg454_5_0002"
                     /evalue="5.80E-05"
                     /label="PKSI-AT-M_m8"
                     /locus_tag="ctg454_5"
                     /protein_end="50"
                     /protein_start="38"
                     /score="16.4"
                     /tool="antismash"
                     /translation="YWGQHLRQTVKFS"
     CDS_motif       complement(12788..12820)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg454_5_0001"
                     /evalue="2.70E-03"
                     /label="PKSI-AT-M_m7"
                     /locus_tag="ctg454_5"
                     /protein_end="26"
                     /protein_start="15"
                     /score="10.4"
                     /tool="antismash"
                     /translation="PRIRFISNVTGT"
ORIGIN
        1 ataaattcat aaggtgagaa ttgtttttcg agaaagcgct ctggtttaaa ttgtttcggc
       61 tctggatata aatcttcacg ctgatgcgtc agataaatac taccaataag cactgtaccg
      121 ggactcaact catagcccat cacctctatt ggggactcta ccaacctcgg aaatgtaaat
      181 aactgagttg ggtaaattcg caaagcttcg ttacaaactg cattgaggta gggtaatgca
      241 acaatactca tgggatctgg tgattcacca agactatcga gttcctcaac cagtcgcgat
      301 cgtacatcag gcaaacgatg aatccagtat aatgaccaag cgatcgcagt tgctgaagca
      361 tcttgagctg cgaatatggg ggataatagg aggtcgcgca cctcttcatc acttaatggt
      421 tcacctgttt catcactagc aaatatcaga tcgctgagga tgtctctgcg tgagggatct
      481 gcttgcacgc ggcgctcttt gacttcagaa tccagcaatt gtaaaagttc ttgccgaagg
      541 tgaagacggt atccccatgg actccatcga cctaaatccc tttgtccaaa gggaagattt
      601 ataacgaact tataaaaggg agattgcgaa tgtttgattg tagaagcaaa tagatgcttg
      661 attttgtcat agcgctctcc ctcacgcaat cccatgacaa cttctatacc cacccggagg
      721 gtgatatctt cgatggtagg gtaggcaatg aaaagttttc caatcgcctg ttgactgata
      781 attttttctg tgagttcgca gatacgttgc ccacaagctt gcatccgctc accgtgaaaa
      841 gcctgcatta agagcttgcg acggtgtttg tggcggaagc catccagctg aagaactcct
      901 tggttccctg tcattaaggc aaaactttgg tttaatgcac ccctagctgt aatttcttta
      961 gtgttggtga aaacctgctt aatccctaaa ggattgctaa tatgcactgt tggtgtagaa
     1021 ccagacatta tggtgacaat gtcgccatag cgtttgtaaa cagcatccat atagccaaaa
     1081 gggtcagcct ggaattggtg attcagtagc caggtggcgg ttttcggtcc tgcgggtagt
     1141 ttcattggtc ttctctactc ccgttcttta tgctactcta tacagagcat tatcaataca
     1201 aattctcaat tgcttggcta attcttgaat attaggttcg atgaatatcg agaaatgatc
     1261 ccctggaact tcaatgacct gtatggggtg gctggaaaat ttaccccaac ctagtaaggg
     1321 gtcatcagta tgaaattctg gattttcaaa gtcatgaata atttcctcgt tagctcgaaa
     1381 gagagtcatg gagtgaggat aagcctgcgg aacgtaatct cgcatagctt ggacatgagc
     1441 tttgaaaagt ttgtaatagc ggagaaaatc cttaatctct gtgtcgctaa agatgaagtt
     1501 ggctttttta ttcactaaat gaaattgctc atttattggt aaatctcgaa gttcctcaaa
     1561 aggaatggaa aagtctattt tactattagt ttttattgct tcagccatgc ggagtaagaa
     1621 ttttgcatcg tcatcttccg ctggtttaat ggcagtttct ggtattatag tatcgatgac
     1681 aagtaacaaa cctactgttt gaccctgcct ttgcaattgc tgtgccattt caaaggcaat
     1741 gacaccaccg taacaaaaac cccctaaaaa atacgggcca ttcggttgta cctgacgaat
     1801 ttcttggagg tagcgagatg ctgtctcctc cacagaaata atttctgggt cctcttgaga
     1861 ggaaggatct tgtaaggcat aaaatggata gtcctcacca agccttctgg acaatttaaa
     1921 gtaagcatta acacctccac cagcgccatg catacagaag aaaggaacct tggaaccatt
     1981 tgactgaatt gcgaccagat gagaattaga actctcatgg acaggctgac tgacaatagt
     2041 tgctagtttt tcaattgtcg ggttttcaaa aagcgtagac aggggaagat tatgcccaaa
     2101 tctgtcgtga atttgagcca ttaagcgaac agctaaaaac gagtgaccac ccaagtcaaa
     2161 gaagttatct gttactccaa tagggttaat atttaggaga ttttcccaag ttttccccaa
     2221 actcaattcc gtaaaattcc ggggagcaac gaaggattga gtggcgtttg gtcggatacg
     2281 gtcgtcggta ggaagagatc gcttgtcaac tttgccatta ggtgtcaggg gtattgcatc
     2341 caatactacg aaagcagacg gtatcatgta atttggcagt ttatcttgca agtagctggt
     2401 taggtgtggt actacctctt gcttatctgt gactacataa gcgatgagac gctgatcgcc
     2461 ttgagtatca tcttgaacaa tgacgacaga ttcttgcaca tctggatgtt gtgcgatcgc
     2521 atatgcaatt tctcccagtt ccacccggaa accacggatt ttgacttggt cgtcacggcg
     2581 acctaaatac tcaagattgc catcgttgag ataacgcgcc aagtcaccag ttttgtacag
     2641 tttggttcct gggacaaagg gattatcaat aaacttttcc tgagttaatt caggatgatg
     2701 caaatatccc cttgccaatc catcaccacc aatatagagt tctccaataa cccctacagg
     2761 agttagttgc aagtggcggt tcaatacgta gacaagagta ttatcaatag ggcgaccaat
     2821 aggaacgctg tttggctgat gtggcaataa actgctgtcg tagtaagtga cgttagcaga
     2881 aacttccgat gaaccgtaaa ggttgatcag ttttgcagat ggcatcaatt ctcggaaagt
     2941 ttgagctaaa ttaacagaca gtgcttcccc actagttatc cagagtttga gatgcgacaa
     3001 attcttggtg aggtgactgt agctatccag gagtaagcgt agcagtgaag gaacaagtac
     3061 gatacgcgta actttgtaat gtgccagagt ttctacgaac agttgtgggt ctttgacaat
     3121 ggcatcggga ataattgcag tgggaattcc ctgaagtaag ggagcaaaaa tctcccatac
     3181 tgagtctaca aagctaatag ctgttttctg gcaacaaacc tcctcttttg tgaagggata
     3241 ggttttccag aaccagtgca agccattgac tgtacctcca tgagtcccca ggacgccttt
     3301 aggagttccg gtggaaccag aagtgtagat cacataggca agattatcag cttttgacag
     3361 actgatgagg ttttcctcac tttctcgggc aatttcgtta aagtgcatgt ccaagtaaac
     3421 ggttttagct gaagaagtcg agagcttttc taatatttcc tgttgggtga ttaacaccga
     3481 tgcttgggaa tcggaaagca tgaagccaag acgttctact ggataacttg ggtcaagggg
     3541 aatgtatgca ccgccagctt tgaggacagc taaaattccc acaaccattt ctggtgagcg
     3601 ttctagacaa atggctacaa gagtttcttt tgttacacca tgtttttgta aataatgggc
     3661 aagttgatta accctctggt tgagttgacg ataagtcagt tcttctgatt ggctaattaa
     3721 agctaatgca tcaggaaatt gctcgacttg ctgctcaaat agttgatgaa gggaggtgtc
     3781 ttgagaatag tctgcattag tttgattcca ctcaaataat agttgctctc gctcgggaac
     3841 tgtgagtggt gacaattcac aaatgcgctg ctcgggattt gcaacaatgc tttccaatag
     3901 agcttggaaa tgagtaatta atcgggtaat ttttgcatcc tcaaaaatgt ctgtattgta
     3961 ctccaaaaac cctgttaatc cctgctgaga ttcggacatt gacaggaaaa tatccaactg
     4021 agctgtaccg ctatcgaact gcaaagtacg cacggttaaa ctagaagctt cctgcacaga
     4081 cgttggagtg ttttgcagga taaacatcac ttcatagagt ggatttcggc ttaaatcacg
     4141 ctcaggttgt aattcctcta caagcatctc aaaaggcaaa tcctgatgtg cataagcatc
     4201 aagagtcacc tcacgcactc gatgtagaag ttcgcggaaa ctgggatcgc cactaaggtt
     4261 attacgcaac accaaagtat tcacaaacaa acccagcatc ccttctagtt ctgctcgatt
     4321 ccggtttgca attggagagc caattaggat gtcttcttgg tctgtgtagt ggtatagcaa
     4381 tagattaaat gctgccagca gagtcataaa caaagtggcg tcttctcgct ggctgaattg
     4441 attcagtgca tctgtcaggg ttttggagaa tgtaaagtat tgcttagcac cagtaaaagt
     4501 ggtaacggta ggtcgtagac gatctgtggg taactgtagt acaggtaaat cgccgcttag
     4561 ttgttgcttc cagtagttga gttgggtttt gagcagttca ccttgcaggc gatcgcgctg
     4621 ccaaacagca aaatctgcat actgaatggg aagttcaggt aagggagaag gttgatttgt
     4681 ggagaacgct gtatatagcg tcgccaactc tcgcatgaac acaccaatag accatccatc
     4741 cgtgataatg tggtgcatgg tcaaaaggaa aacgtgttct tcttcaccca aacgcaataa
     4801 agttgctctg actaaaggtc ctttagctaa gttgaagggt tttttggctt cctcagctgc
     4861 aagttgttta acttcaggtt cccaatcttt tccaaacaaa tgctcaaaat ttatgatggg
     4921 taagtcccaa gtgaattccg gtgcaatctc ctgcactggc tctccattta cgagtgcaaa
     4981 agtcgtgcgc caaacttcgt gacgcctaag aatttcattg agactttgct ggagtgctgt
     5041 aatattcagc gaacccatta aatgagatgc acttggaata ttgtaaaagg aactcccgtg
     5101 gtaaagttgg tcaataaacc acagcctttg ttgggagaaa gacaagggag tattgtggga
     5161 ggcttgacgc ccaggaatag tatcagcttt aaattttccc cccttccatt tttccagaag
     5221 ggcttttttg gcaggtgata aattagagtg ttgtttatcc atttgttcgt agttgcgctt
     5281 tagcgctctt ttacttctga accgcgagga atatctattt taatgaaccg ccttctctgc
     5341 gagaggctcc gccaacgcgc agcgcatgcc cgaagggctg taggcgcgaa gaacgccaag
     5401 aaagaagtaa gaaggcagaa ggcagagggc agaaggcagc tatgatccca cgcttaaaaa
     5461 cgtgggattc aaacaaggac gagaagagtt tctcgcgccc ttcgggtgac gctcgagtac
     5521 gacgctcgtt cctcgctatc gcttcgctaa cgtcagttgc tctacttggg gagaccccaa
     5581 gaccgcactg actcactgcg cgtctcgcac tcctccgcat attttttgtt acgaatgaat
     5641 ccgtgggctt tgacccgtca tgggcaagcc ccggcagaaa gcattccatt cccgtataaa
     5701 ccgttacatc aacatagctg cctcctgcct tctgccttgc ccgaagggct gtaaagaaga
     5761 taggtaatat tacactgaga acggagtagc taaaagaact gctacttcct cttccgataa
     5821 ttcttcgatt ttctctagga gaagttgctc gatcatttct gcttgcttgg ctggtatcat
     5881 tgcttgtagt aaaaagtcac gcagtggtaa ctctaccggg aactttgctc gcaatcgaga
     5941 aaccagttga gttgcaatga gggagtctcc tcccaactca tagaagttgt cataaatacc
     6001 aacttgggca attccaagaa cttcttgcca gatttcggca atttgttttt ctaactcgtt
     6061 actgggagca acataggaat tacccaggct aggtctggaa tagcgtgagg atgagtctac
     6121 ttgagtggaa gattttgaat atagtcgaga gtcaagttta aatgcgcgat cgctccgggc
     6181 tttgatatct accgtagaaa caatcacctg agttgcttct cctaaagaga atattcgttt
     6241 aaagacttct acactttctg tttccgtgat agccaattcc atcccggact gtccaagtat
     6301 tttttgttct tgggttgcat ttaggtgcaa tttgtccaaa tttatggaaa tccaagggaa
     6361 agaattagtt tgattatgtt tttgagtaaa ggtatctgtt aactggttaa ctcctgagta
     6421 taaagctaac ccaaatccac ccaaaatgga agatagagaa gaaaaaatga tacaaaaatc
     6481 taacttccta ctttgtaaga ctttttctaa tagggtgatt ttatcgttct gagagtccag
     6541 tagtttttct aactctgtct tagcaatttc tggaatcgag caaaacatat tttcgcgtgt
     6601 tcttccagtt aaatagataa taccatgaat ttgaccaatc ttttcaagtg ctaagcagga
     6661 gtgcatttgt tcatagttag ttgtatctgc acgtaccacc aaaacttctg cacccagagc
     6721 ctctaatgat accaagtttt ggattttgcg actcacctca tcttcttgag catgagtttc
     6781 tagccattgc gagtattcat cctttccggg aaaagcggaa tcctcgataa atatgagttt
     6841 tgcttgtagg gtttttgcga gatatcccgc tagcacaact ccaatacttt ctagtccgcc
     6901 aggaaacagg taaacaccct gctttctcaa tggtattttt tcttcaactg ctgactctag
     6961 gcgcacaggc tcaaacgttt gtacccaacg gtagcgatcg cgataagcaa caactaagtc
     7021 agatgacaaa gacgtaaact cacttataat ttggtcaacg atatgagcgg cacaatttcc
     7081 tgttcctccc tctgcgtcct tggcgtcttg gcggttcgct aagacaaaat ctatattccg
     7141 acaagtgata ttggcatact cttgaggaat aaccttacat aaccctaaaa ccgttgcttt
     7201 ctctggatca agcctttcat tcccattgac ttcttgaatc tggttcgaca caacccaaac
     7261 ttgcaggcga tcgctaattt tgtgtttacc tagagcctgc gttaaaaaca gcaaactttt
     7321 aaattctaaa aactcaccct gttggcgagt cccaaaagta ttcagactcc ataaatgagc
     7381 aatgtgttgc ggagttttac ccagttcaat cagttcttgg aacaacacat cgtactcatc
     7441 gcggttttgg ggatgaatag cataaattcc ctcacgcaat ttagtaaact gctctcccac
     7501 cttcaccaca atcacatttt tgccattctg ttctagtctg ttaactaact gggaacccac
     7561 tccagactca tcaacaaaca gcaaccattg ctcttgtgca gattcgtttt gattcgggga
     7621 ggatgaacca ggaagcaagg agcgtttcca tgaaggaata tagaaccagt cggcaatgtc
     7681 ttgttttttg tccaatgtta ctggcttacc acttgaagaa gaagatggcg attttgcatc
     7741 aatccagtat ctttgtcgct caaaggggta agtaggcaaa ggcagacgat gacgctgctc
     7801 gtgggtgtag aaccctgacc aatctatttc tacaccagaa agccacaacc gacctaatgt
     7861 ctgtaataaa aagctaacat ccgattgttg ttcttgagca tgagctaaag aagtcagcac
     7921 aatttgtttt gcttctggtt ttaaatgctg tgttgttaat gtgcttaatg tccgtcctgg
     7981 actcacctcc aagaaaacac cttcaaattg ttgtaacaat tgagatatcc catcagaaaa
     8041 ttttacagtt tgccgtaaat gttgacccca gtagttggga tttgtggctt gaccatctgt
     8101 aatccatgtg ccagtgacat tggaaatgaa gcgaatacgc ggcgggttga gcttcacttt
     8161 tttcagtacc tgcacaaatg gttccaagat cggttccatc atgtgggaat gaaaggcatg
     8221 tgatgtatgt aacagacgac aatcaatccc ttgggaagat aattggtttt ggagggtagc
     8281 gatcgcatca ctagaaccgg aaactacgca cgaggatgga ctgttgattg ctgctatttg
     8341 tagagacgtt ccatggaacg tctctacatc ttctatgagg gattgcacgt ctttttccgg
     8401 aagtggaatg gcaagcatac ttcctctggg caactgttgc atgagttgtc cccttgttga
     8461 cacaatcgcc aaggcatctt ctagggaaaa tacacctgca attgttgctg cgacatattc
     8521 cccgatgctg tgaccaatca tcgcttctgg attcactccc cattctatcc acaactgggc
     8581 aagggcgtat tcgatgacaa acagtgcgct ttgggtaatt gctgtttgtt gcagttgttg
     8641 ggtagctgtt tgagtgtgtt gagggtctgg ataaagtata tggcggatat caaaattgag
     8701 caggggcttc agaatgtcag cacaaatatc tacatatttg ccaaatgtgg gttcaaccga
     8761 gtacagttcc cgtgccatat tcacatattg cgctccttgt ccggaaaaca tgaatacgac
     8821 tggacggtga ctgggcttgc ggtggtaagt gaaaacatgt tgcacgtctt gggatttcag
     8881 tattttgact gcatcctcag agtcatgaca tattaccatg cggcgatggt caaatgctcg
     8941 gcgacccact tgcagagtgt gagccacatc cgccaggttt aaatcggggt attgctggag
     9001 gtgagtagct aaggaagctg tggtagtttc tagggctgta ctggttttgg ctgaaaggag
     9061 taacaactgc caagggcgtg aagcactcga cggttcaact attggggctt gttccaagat
     9121 aacatgggca ttagtccctc ctataccaaa cgaactgaca cctgctcggc ggggagttcc
     9181 attagttttc cactccgaca gcttagtatt gacgtagaag gggctgttgg cgaagtctat
     9241 ctcaggattg ggttgttcaa agtgcaagct aggcggaatc atcttatgtt tcagtgcttg
     9301 tactgttttg attaagctag taataccaga agctacattc agatgtccaa cattaggctt
     9361 taccgagcct atggcacaga atcccttctt tttagtgcat gcttcaaatg tcttcttcag
     9421 ggcactgatt tcaatagggt ctcccagggc tgtaccagtt ccgtgggtct caatgtaggt
     9481 aattgtctcc ggattaaacc cagcgttcgc ctgagcctca acaattactt tggattgacc
     9541 acccacacta ggagctgtgt aacccacttt catggcacca tcattattga tagctgaacc
     9601 tttgatgact gcgtgaatgc aatcaccatc gtctaaggca tcttctaatc tcttgaggac
     9661 gacaataccc actccgtcac cgaaaatagt tccccgtgct ttagcatcaa aggcgcgaca
     9721 gcgaccatca ggagaagtca tccccccttc ttcatagaaa taaccttgtt tttgcgaaga
     9781 ctgtattgaa ataccgcctc ccaaagccag atcgcactcg tagttcagca atccttgaca
     9841 cgccgaatga acagctacca atgacgtgga gcaagctgtg ctaatattta tactcggtcc
     9901 tttgaggttt aacttgtatg aaacttttgt agctaggtgg tgctgaccat tgctcaattc
     9961 aactaacgaa cccatcgatt taattagatc agggttggaa ctgaattggc taagcaaata
    10021 gacactcagg tttgttcccg cataaacacc agtcaacctt ttgtctgatc caggagcata
    10081 gccagcagtt tctagtgctt cccaagcaca ctcaaggaaa atacgttgtt gcgggtccat
    10141 gatttcggct tcccttggcg agaaatcaaa aaagggagcg tcgaacaggt caatgtctga
    10201 cagacgagca ccagctttga tatagttggg attgcttagt aatgctgggt ctatgcctga
    10261 atcctctaat tcttcattgc tgaagaaaga aattgattcc tgcccattgc acagattctg
    10321 ccaaaattca tcaacacctt tggcttttgg aaaacgaccg accataccga ttacggctat
    10381 gcctttaatg gcatcgtgga tttgttggtt atccatctac cttcttcctt tgtttcatca
    10441 attttctttt ttcttgcata gccgcttctt ttctgctggc acgttcatca gcttgttgaa
    10501 atgttggttc ttcaacctgt tttccgccga gatattctgc taaagcattt atggtcgaat
    10561 attcaaatag atcggcgatg gagagatttt tgttaagcgt ttttagaagt ttactgcgaa
    10621 cctgaattaa gagtagtgaa tctcctccta attcaaagaa attatcataa agtcctacat
    10681 cttttattcc aataacttct tgccaaatgt tggcaatctt ttgttcaatc tcatttgtaa
    10741 gaggaaagta tggaatttgt aaatctggtc tgggatgaag tgataaggaa tttgcttgtt
    10801 ggctatctac tttctgttga aaagattcgc tctgaatcca tcggtcaatt ctagctttaa
    10861 gttctccagt cgagacaacg acatgattga attcacacca gttcaaaatc ctttgaaaag
    10921 cttctacacc ttctttgggg ttgaacgcaa attcagccac acgtgcgcct accaatgtac
    10981 tttgtttatt ttctttttcc agttgccagc catcccagct tacgctgatc cacgagaaag
    11041 gatggctctg attatgttgg tgcacaaaag catccatgaa gatatttgct gctgagtaag
    11101 caacaaatcc taatcctcct aacacagatg ataacgaaga caacaagaaa caaaaatcaa
    11161 tatctctgtc ttgcaaaacc ttttctaata ctaaaagtcc gtgtactttt ggttgaaatt
    11221 gctgctcaca atcagtttga cttatctttt caatagctgc aaaagacctg cctccaacaa
    11281 ttccagcagc atggataaca ccattgagtt gaccaaaccg tgactctgct tgagcgatcg
    11341 cctcttgcat ttgttctgta ttgctcacat cagcactcac caccaaaact tctgcaccca
    11401 actgttcgag ttgttgcact ttttgaatct tgcggctggt gctatcagtt tcatcatgag
    11461 tgagcaacca ttgttcccat tcgtctcgat ggggtaaagc tgtacgtccg atcaacagca
    11521 gttttgcttg cagagtttta gccaagtatt ctgctatgac ttgtccgata cctccgagtc
    11581 cacctgtaat cagatagact cccttttccc ttaatcgcgc ctttccaatt ttcgcttcat
    11641 caaagcgcac tggctcaaaa gattgcaccc aacgattgat acctcggtaa gcaatcactt
    11701 gatcagaggt gggaactgtc agttctgcca ctaatctttc tacaagtttt tcttcaagcc
    11761 aactacctgt tggcggaaga ataacatcaa tactccgaca tctgatattt aagtattctt
    11821 gagatataac tttaatcggt ccaagtaaag ttgctttctc tggacaaagc acctcagttc
    11881 ctgttactgg ttgtaagtta ttggaaatga ctgtgatttg aaaatcatcc ggagtttcct
    11941 ttcttcccaa agcttgggca agaaatagca gactgtaaaa tcctattgct tgggctaggt
    12001 caacttcttc aagttctaat tctttgtcac caacaggtgt gacactccac aaatgaacaa
    12061 ttgtttttgg caactgctgt tgtgtgagaa gttccttaat taaggcttcg taatcatagg
    12121 gttgttgagg atttaaggta tattgggact cgctgatctg agtgaactca cctccgactt
    12181 ttacagtaat gacatcctgg ttttgttgtt ctagttgttt taccagttta gtacccaaac
    12241 cacactcatc gataaacacc aaagtacaag atttttgctc tgctaatttc tcctgattga
    12301 ggggtactgg tggtgaagat ggtttccaga aaggaatata gaaccagtcg gcaatgtcgg
    12361 gcttttcgcc cagtgatact ggagtaggac gctcatcaat tccttgtttt ttgggttcaa
    12421 tccagtatct ttgtcgctca aaggggtagg taggcaaagg cagacgatga cgatgctcgt
    12481 gggtatagaa tcctgaccaa tctatttcta caccagaaag ccacaaccga cctaatgttt
    12541 gtaacaaata gctaacatcc gattgttgtt ctttagcatg agctaaagaa gccagtacaa
    12601 tttgttttgc ttctggtttt agatgctgtg ttgttaatgt acttaatgtt cgtcccgggc
    12661 ccacctccaa gaacacacct tcaaattgct ctaacagttg agatatccca tcagaaaatt
    12721 ttacagtttg ccgtaaatgt tgaccccagt agttgggatt tgtggcttga tcatctgtaa
    12781 tccacgtacc agtcacatta gaaatgaagc gaatacgcgg taggtttagc ttcacttttt
    12841 tcactgcttg cacaaatggt tccaaga
//
