LOCUS       c00093_3300009..        9528 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300009767.a:Ga0116161_1006102.
ACCESSION   c00093_3300009..
VERSION     c00093_3300009..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-24 14:49:07
            Original ID  :: 3300009767.a:Ga0116161_1006102
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 9528
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..9528
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1:4195](+)"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2..4195
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..9528
                     /SMILES="NC(Cc1ccc(O)cc1)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..9528
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="(cds(Condensation and (AMP-binding or A-OX)) or
                     (Condensation and AMP-binding))"
                     /tool="antismash"
     CDS             2..4195
                     /NRPS_PKS="Domain: Condensation_LCL (5-269). E-value:
                     1.3e-39. Score: 127.7. Matches aSDomain:
                     nrpspksdomains_ctg93_1_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (425-817). E-value: 6.7e-94.
                     Score: 306.5. Matches aSDomain:
                     nrpspksdomains_ctg93_1_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (923-991). E-value: 2.8e-19. Score:
                     60.9. Matches aSDomain: nrpspksdomains_ctg93_1_PCP.1"
                     /NRPS_PKS="Domain: NAD_binding_4 (1039-1278). E-value:
                     3.7e-35. Score: 112.9. Matches aSDomain:
                     nrpspksdomains_ctg93_1_NAD_binding_4.1"
                     /NRPS_PKS="type: NRPS"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_binding_4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     141.2; E-value: 9.2e-43)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg93_1"
                     /sec_met_domain="Condensation (E-value: 3.2e-44, bitscore:
                     139.5, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 2.6e-104, bitscore:
                     337.4, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_binding_4 (E-value: 3.7e-36, bitscore:
                     112.9, seeds: 102, tool: rule-based-clusters)"
                     /sec_met_domain="RmlD_sub_bind (E-value: 3.2e-15, bitscore:
                     44.3, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="DWEKARDALQYNIPIAILIAGYALPDTARLKEAMLAVMEIHPYLK
                     IRLVIRDGQILQQRRDTQTVEILVINSDESRMDSVMNRFVQPFDLFHDDLYRFEIHRTQ
                     KNVYLLMDFHHIAFDGFSMGIFLQDLKSALEGKGLSAEAVSAFDVALYEQEALGSEAFS
                     KAEKYFDELTGGECSMSVIPPSTRIPETREKGSCEEILPGKEIDAFCKDYGVTANTFFL
                     SVLCQAVQRFTREQDVVLTISSGGRADARLDRTVGMFVKTLPVKTKITPRKFVEFAKDL
                     QEQVFSTMEHDIFPFTRMVEKYGIIPQINYVYEGGLGIEMSLDNVPLDIIFLDLESAKF
                     PFGIVAEPCDRGYKLSVQYDVLKYAKEDVGRFLSLYRNIALQAARQPVTLTSELELMDD
                     RERALVLQYSRGAYLPYDTTKTFIDLFRENVRKYPDNIAVTDKQGSLTYKQLDAWSDSL
                     ASELATLGVVPGTFVAVMLIRCKEFVVSILAIQKAGGAYIPMDSEYPNDRLLYMLENSE
                     SKVLVTQRELYRSKQQAGNFEVNQVLFVDEFDFTAFAKCEIQPPKPEDLAYMIYTSGST
                     GKPKGVMIRHRSLAAKVHWQMHDFEMTSSDNNICHPSFSFDASVDDLFGPLAAGGTVHI
                     LWEEIRQNMVDLYKYTIHNQITGGSFSTQFGMELVNQFELPLRYIVMGGEKMVQLKKRN
                     VQIINGYGPTEFTVCSSYHKVNQEKDTHNIPIGKPVPNSWSYVLDNNLQLLPPGIPGEL
                     CLAGTQIAMGYWKRDDLTAERFVNNPYATGPENSKLYRTGDLVCWNNSGEMEYMGRIDT
                     QIKLRGFRIELGEIEAMMAKTVGIAAAVADVKEIGGEQQLVGYYIVEPYGKVDQATLDA
                     WLRTGLTAYMVPSAYMEMNSFPLTPNGKVNRKLLPLPQMARIQPYVAPTNKLEEDLCSI
                     YEEILQLEKVGILDDFFRIGGTSMSAIKAIIRIINLGYDIQYGELFEHKTPQAIARFLT
                     ESEQEKAKKKEQDGKKNIADYDYSAINKLLDKARPNLWDGYRPLPTGDVLLTGATGYLG
                     MHLLKELIEEEDNVIYCMVRSKGTLTPERRLKSQLMYYFSDTYDSLFGKRIIPVDLDIT
                     NKGTLESLKGLGIGTVYNCAAVVKHYAAGDELEKINVKGVSNLVDFCRSDNARLIHIST
                     VSVSGMRYRDQAGDKALDEGSLYIGQEIDNPYVRSKFLSERIVLEAIAGGMNGKVMRVG
                     NLMGRHSDGEFQINFNSNAFINTLKSYKMLGMFPLSGLIAPTEVSPIDCVARAVHVLSK
                     TPSEVVLLHAYNNNRLDMASMIFAMKEYGFDIELVSDERFRQRFNEMMKNPAMSEYLGG
                     LLHYGIDTEKVPVPDDNSYTTLLLYRNNVRWPLADEGYSLKLIKMLDGMGFFVN"
     aSDomain        17..808
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg93_1_Condensation_LCL.1"
                     /domain_subtype="Condensation_LCL"
                     /evalue="1.30E-39"
                     /label="ctg93_1_Condensation_LCL.1"
                     /locus_tag="ctg93_1"
                     /protein_end="269"
                     /protein_start="5"
                     /score="127.7"
                     /tool="antismash"
                     /translation="RDALQYNIPIAILIAGYALPDTARLKEAMLAVMEIHPYLKIRLVI
                     RDGQILQQRRDTQTVEILVINSDESRMDSVMNRFVQPFDLFHDDLYRFEIHRTQKNVYL
                     LMDFHHIAFDGFSMGIFLQDLKSALEGKGLSAEAVSAFDVALYEQEALGSEAFSKAEKY
                     FDELTGGECSMSVIPPSTRIPETREKGSCEEILPGKEIDAFCKDYGVTANTFFLSVLCQ
                     AVQRFTREQDVVLTISSGGRADARLDRTVGMFVKTLPVKTKIT"
     aSModule        17..2974
                     /complete
                     /domains="nrpspksdomains_ctg93_1_Condensation_LCL.1"
                     /domains="nrpspksdomains_ctg93_1_AMP-binding.1"
                     /domains="nrpspksdomains_ctg93_1_PCP.1"
                     /locus_tags="ctg93_1"
                     /monomer_pairings="tyr -> tyr"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       338..394
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg93_1_0001"
                     /evalue="8.70E-09"
                     /label="C3_LCL_132-143"
                     /locus_tag="ctg93_1"
                     /protein_end="131"
                     /protein_start="112"
                     /score="27.9"
                     /tool="antismash"
                     /translation="FHHIAFDGFSMGIFLQDLKS"
     CDS_motif       710..796
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg93_1_0002"
                     /evalue="2.80E-05"
                     /label="C5_LCL_267-296"
                     /locus_tag="ctg93_1"
                     /protein_end="265"
                     /protein_start="236"
                     /score="16.6"
                     /tool="antismash"
                     /translation="DVVLTISSGGRADARLDRTVGMFVKTLPVK"
     CDS_motif       1226..1252
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg93_1_0003"
                     /evalue="4.60E+01"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg93_1"
                     /protein_end="417"
                     /protein_start="408"
                     /score="-1.3"
                     /tool="antismash"
                     /translation="SRGAYLPYDT"
     aSDomain        1277..2452
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg93_1_AMP-binding.1"
                     /evalue="6.70E-94"
                     /label="ctg93_1_AMP-binding.1"
                     /locus_tag="ctg93_1"
                     /protein_end="817"
                     /protein_start="425"
                     /score="306.5"
                     /specificity="consensus: tyr"
                     /tool="antismash"
                     /translation="FRENVRKYPDNIAVTDKQGSLTYKQLDAWSDSLASELATLGVVPG
                     TFVAVMLIRCKEFVVSILAIQKAGGAYIPMDSEYPNDRLLYMLENSESKVLVTQRELYR
                     SKQQAGNFEVNQVLFVDEFDFTAFAKCEIQPPKPEDLAYMIYTSGSTGKPKGVMIRHRS
                     LAAKVHWQMHDFEMTSSDNNICHPSFSFDASVDDLFGPLAAGGTVHILWEEIRQNMVDL
                     YKYTIHNQITGGSFSTQFGMELVNQFELPLRYIVMGGEKMVQLKKRNVQIINGYGPTEF
                     TVCSSYHKVNQEKDTHNIPIGKPVPNSWSYVLDNNLQLLPPGIPGELCLAGTQIAMGYW
                     KRDDLTAERFVNNPYATGPENSKLYRTGDLVCWNNSGEMEYMGRIDTQIKLRG"
     CDS_motif       1463..1504
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg93_1_0004"
                     /evalue="6.20E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg93_1"
                     /protein_end="501"
                     /protein_start="487"
                     /score="13.3"
                     /tool="antismash"
                     /translation="LAIQKAGGAYIPMDS"
     CDS_motif       1700..1759
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg93_1_0005"
                     /evalue="1.30E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg93_1"
                     /protein_end="586"
                     /protein_start="566"
                     /score="33.1"
                     /tool="antismash"
                     /translation="AYMIYTSGSTGKPKGVMIRHR"
     CDS_motif       2237..2326
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg93_1_0006"
                     /evalue="2.50E-13"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg93_1"
                     /protein_end="775"
                     /protein_start="745"
                     /score="42.2"
                     /tool="antismash"
                     /translation="PPGIPGELCLAGTQIAMGYWKRDDLTAERFV"
     CDS_motif       2417..2482
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg93_1_0007"
                     /evalue="7.90E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg93_1"
                     /protein_end="827"
                     /protein_start="805"
                     /score="37.1"
                     /tool="antismash"
                     /translation="YMGRIDTQIKLRGFRIELGEIEA"
     aSDomain        2771..2974
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg93_1_PCP.1"
                     /evalue="2.80E-19"
                     /label="ctg93_1_PCP.1"
                     /locus_tag="ctg93_1"
                     /protein_end="991"
                     /protein_start="923"
                     /score="60.9"
                     /tool="antismash"
                     /translation="EEDLCSIYEEILQLEKVGILDDFFRIGGTSMSAIKAIIRIINLGY
                     DIQYGELFEHKTPQAIARFLTESE"
     aSDomain        3119..3835
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg93_1_NAD_binding_4.1"
                     /evalue="3.70E-35"
                     /label="ctg93_1_NAD_binding_4.1"
                     /locus_tag="ctg93_1"
                     /protein_end="1278"
                     /protein_start="1039"
                     /score="112.9"
                     /tool="antismash"
                     /translation="LTGATGYLGMHLLKELIEEEDNVIYCMVRSKGTLTPERRLKSQLM
                     YYFSDTYDSLFGKRIIPVDLDITNKGTLESLKGLGIGTVYNCAAVVKHYAAGDELEKIN
                     VKGVSNLVDFCRSDNARLIHISTVSVSGMRYRDQAGDKALDEGSLYIGQEIDNPYVRSK
                     FLSERIVLEAIAGGMNGKVMRVGNLMGRHSDGEFQINFNSNAFINTLKSYKMLGMFPLS
                     GLIAPTEVSPIDCVARAV"
     CDS_motif       3680..3748
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg93_1_0008"
                     /evalue="1.90E+01"
                     /label="C5_dual_260-291"
                     /locus_tag="ctg93_1"
                     /protein_end="1249"
                     /protein_start="1226"
                     /score="-1.1"
                     /tool="antismash"
                     /translation="LMGRHSDGEFQINFNSNAFINTLK"
     CDS             4274..4807
                     /locus_tag="ctg93_2"
                     /transl_table=11
                     /translation="MMVHNPWHSVEPDLEGFEVNALIEISNGSRAKYELDKVTGLLRLD
                     RVLYSAVYYPANYGFIPRTFAKDDDPLDVLVLSQIPIQPLCIVRVKIIGVMQMIDQGKP
                     DDKLISVACHDKSVSHLEEIKGMPPIFDSELKQFFEEYKRLENKTVLVEEFADRIHALE
                     ILEDSLQRYRELYQ"
     CDS             4965..6680
                     /gene_functions="other (smcogs) SMCOG1206:transposase
                     (Score: 148.1; E-value: 6e-45)"
                     /gene_kind="other"
                     /locus_tag="ctg93_3"
                     /transl_table=11
                     /translation="MLKTANENKNTNIFLKDKILRGVTGYKQIRFIEGYINNETVDVTA
                     RLTLSYARCPLCGKKSHSVHSTYERQLMDLPIHGKRMNIRLLARKFRCRNLKCRQIVFS
                     EQPTGIAERYSRKTIVAKSKLQSILIEMSATKGALIVSSMGMSQSASTCLRLIKSIEIK
                     VNKASVKHICIDDFAYRKGNKYGTIIIDADTSKTIALINSRETDHVATALKAYPNVQTV
                     SRDRSSAYANAIKQGIPEAAQIADKFHLVKNCGEHMEAQLKKSFNQIKDELSKQISEPL
                     PPPVSSYPTIDNPEPVQLSSRPPSEKQRYLFKQVQKLNKENYSEREIVRHLHISRGLVR
                     KYLSLNEPQGNKIAFRNDYSLFLPIVQNGIHNKARISEIYRNSVNAGLCCSYIAFLNWM
                     RTVFPEYKTFKGKATRNSRVDSTGYDRTKSVLKALSSYKLNIYIANPEWGINKKTGQCS
                     KENIQMNEIIQSSSTLLKLREFCVSFKAVIAGNSISDIVAWIEKYKNESFAHLRTFATG
                     LIKDIDAVKNAILYPYNNGLAEGLNNKLKALKRGMYGRAGNRLIEIKMVASLTG"
     CDS             complement(6800..7441)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1115:HAD-superfamily hydrolase, subfamily IA, variant
                     (Score: 94.9; E-value: 8.9e-29)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg93_4"
                     /transl_table=11
                     /translation="VKTIQYILFDFDGTLADTFDLVFTLYNSIAGEYGCKPLKPEDRQI
                     IAAGKPQDLLRQYNMSAHKLGLITIRIRKEILSHVPQMKPFEGMKEVLTTLRDKDYRLG
                     IITSNARPNVVLFLENNGMNSLFDFVYSGKSLFGKDKVFKRMLANKKIHPASAIYVGDE
                     TRDIEACRKVGIPIVSVTWGMNNREILSTLNPDQMAHTPQEIIRCIAALS"
     CDS             7630..9525
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg93_5"
                     /sec_met_domain="Abhydrolase_6 (E-value: 3.5e-12, bitscore:
                     35.8, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 4.9e-10, bitscore: 27.8,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKLIFWFFLSSSCLVYAQKQTEVYLIGSVHAMHLNQEYHYSLTD
                     LMAQIQKIKPDIVCGEITPDAYNSVFEGYFPPEAAMLAQMAPVVGYQFVPVDWRADFIL
                     QQEAERHYPRKIKDEINKVASWANTYENSGLPSLYDHIHSKSTLKTIDQVYEMIISDSI
                     ANRAHGFWRERNRAIVKNGMSSLHDVGRVVFVFGVDHMSRLIRELENYDVQILIPERMF
                     DADHSVQITEDVCKRWALSLENLQLIKDRKIEVTPGYYQKIINSNRITELQRFLDYYST
                     PYANGQDLEYILAKESIRDLDSIVTPKGIWENFELAIGGINQSVYTRGNDRDNPVIIFV
                     HGGPSSPMSPVMWMYQRPLEEFFTMVNYDQRGAGKTYLRNDTTLLSNTMTIEWFVNDLI
                     ALTDSIRQRYCKEKVILMAHSWGTVVSMNAVLKRPDLYYAYVGLGQVINFMDNERLCFE
                     FGLNQARRSNDSTAIKEMESVAPYPGDNPVTDGRISIVRKWAQYYGGFTAYRKVPKFYY
                     YAPLLSPDYSSLEREAIDGGALFTIPKILPELLKVDFKHVDKFPIPVFMFMGRHDFTTP
                     AEPVLDWIHRVKAPLKRAIWFENSGHLIPLEEPGKMLVTLLHEVRPLADNSNSKR"
ORIGIN
        1 cgattgggaa aaagcacggg atgccttaca gtataacatt cctatagcta tccttatagc
       61 cggctacgca ttacccgata ccgcgcggtt gaaagaggct atgctggccg ttatggaaat
      121 acatccgtac ctgaaaatac gtcttgtgat acgcgatggc cagatcttgc agcagcgccg
      181 agatacccag acggtagaga ttttggtgat caattccgat gaaagcagaa tggattcggt
      241 tatgaatcgt tttgtgcagc cttttgatct tttccacgac gatttgtatc gttttgaaat
      301 ccatcgcacc caaaaaaatg tttacctgct gatggatttc caccacatag cctttgatgg
      361 tttttccatg ggcattttcc tgcaggacct taaatcagct ctggaaggga aaggcttgag
      421 tgccgaggcg gtatctgcct tcgatgtcgc cctgtacgaa caggaagccc tgggctccga
      481 ggcattttcc aaagccgaaa agtactttga tgagctcacc ggtggtgaat gctccatgtc
      541 tgttatcccg ccatcaacca gaattccgga aaccagggaa aagggaagtt gtgaagaaat
      601 cttacctgga aaagaaatcg acgcattctg taaggattac ggcgtaacag ccaatacctt
      661 cttcctgtcg gtgctgtgcc aggccgtaca acgcttcacc cgcgagcaag acgttgtatt
      721 gaccatctct tccggcggac gtgcagatgc ccgccttgac cggaccgtag gcatgtttgt
      781 taaaacgctg ccagtaaaga ccaaaataac gccccgtaaa tttgtggaat ttgccaaaga
      841 cctccaggag caggtattca gtaccatgga acatgatatc ttccccttta ccaggatggt
      901 agaaaaatac ggcatcatcc cgcaaatcaa ttacgtctat gagggcggcc tgggaataga
      961 aatgtctctg gacaacgttc ccctggatat tatcttcctg gaccttgaaa gcgcaaaatt
     1021 cccctttgga atagtcgcag agccgtgtga ccgggggtac aaactgtcag ttcagtacga
     1081 tgttctaaaa tacgcgaagg aagacgtcgg gcgttttctg tcgctctaca ggaatattgc
     1141 tttgcaggcc gccagacagc ctgtaacact tacttcggaa ctggagctga tggacgaccg
     1201 ggaacgggcg ctggtccttc aatattcccg cggggcatac cttccttacg acactactaa
     1261 gacgttcatt gacctgttcc gggaaaatgt gcgcaaatat ccggacaata tagctgtgac
     1321 cgataaacag ggctcactga cctataagca gctggatgcc tggtcggata gcctggcctc
     1381 tgaactggct accctgggag tggttccagg cacctttgtt gccgttatgc tcatacgttg
     1441 caaagaattt gttgtcagca tcctggccat tcagaaagcc ggcggggcat atattcccat
     1501 ggacagcgaa taccccaatg accggttgct ctacatgctc gaaaacagcg aatcaaaagt
     1561 gctggtcacc cagcgtgaac tgtaccggtc aaagcagcag gccgggaatt ttgaggttaa
     1621 ccaggtactc tttgtagatg aatttgactt cacagccttt gcaaaatgtg aaatacaacc
     1681 acctaaacct gaagatcttg cgtatatgat ctacacttca ggttcaaccg gaaaaccaaa
     1741 aggggtgatg atccgtcaca gatcactggc tgctaaagtt cactggcaga tgcacgattt
     1801 tgagatgacg tcttccgata acaatatctg ccatcccagc tttagttttg atgcgtctgt
     1861 agacgacctg tttggcccgc tggcagccgg agggaccgta cacatactct gggaagagat
     1921 tcgccagaac atggtagatc tttataaata caccattcac aaccaaatta cggggggatc
     1981 attcagcaca cagtttggta tggaactggt caaccagttt gaactgcctt tacgctacat
     2041 cgttatggga ggcgaaaaaa tggttcagct aaaaaaacgt aacgtacaga taataaatgg
     2101 ttacggacct accgaattca ccgtttgctc cagttatcat aaagtaaacc aggaaaagga
     2161 tacccacaac attcccattg gcaaaccggt acccaactcc tggtcttatg tactggataa
     2221 caacttgcaa ttattgcccc ccgggattcc cggggaattg tgcctggccg gcacacagat
     2281 agccatgggt tactggaaac gagacgacct gacggcagag cggtttgtaa acaacccgta
     2341 cgccaccggg cccgaaaaca gtaaactcta caggaccggc gacctggtat gctggaacaa
     2401 cagcggagag atggaatata tgggccgcat agatacccag atcaagttac gcggattccg
     2461 gatcgaactg ggagagatag aagccatgat ggcaaaaacc gtgggtatag cagccgccgt
     2521 ggccgatgtg aaggaaattg gcggtgagca gcagctggtg gggtattaca ttgtggaacc
     2581 ttatggaaaa gttgaccagg ccacattaga tgcctggctg cgcacgggac tgaccgccta
     2641 catggttccc tcggcttaca tggaaatgaa ttccttcccc ctgacaccca atggcaaggt
     2701 gaaccgcaaa ctgcttcccc ttccgcaaat ggccaggatc cagccctatg ttgctcccac
     2761 aaacaaactg gaagaagacc tgtgtagcat ctatgaggaa attctgcaac tggaaaaagt
     2821 ggggatcctt gacgatttct tccgcatcgg cgggacttcc atgtcggcca tcaaggccat
     2881 catccgcatc atcaacctgg gctatgacat ccaatacggg gaattgtttg aacacaagac
     2941 gccacaggct attgcccggt ttttaacaga atcggaacag gaaaaagcca aaaagaaaga
     3001 acaggatggg aaaaagaata ttgccgatta cgattactcg gccatcaaca aactgctgga
     3061 taaggcgcgc ccaaatctct gggacggcta ccgtcctttg ccaacgggtg atgtgctcct
     3121 taccggggct actggttacc tggggatgca tctgctcaaa gaactgatag aagaagaaga
     3181 taacgtgatc tattgcatgg tccggtcaaa gggtacactg acacctgaaa gacgcctgaa
     3241 atcacagttg atgtattatt tttcagatac ttatgactcg ctatttggca aacgcatcat
     3301 tccggtagac ctggacatca ccaacaaagg aactttagaa tcccttaaag gactgggcat
     3361 aggaaccgtt tacaactgtg ccgcggttgt aaaacattat gcagcagggg atgaactgga
     3421 aaagatcaat gtaaaggggg tctctaacct ggtggatttc tgccgtagtg acaatgcccg
     3481 gctaatccat atatccacag tcagcgttag cggcatgcgt tacagggatc aggccgggga
     3541 caaagccctg gacgagggtt cgttgtacat aggacaggaa atagacaatc catatgtcag
     3601 gagtaaattc ctttcagaaa ggattgttct ggaagccata gcaggtggca tgaacggcaa
     3661 agtcatgagg gtggggaacc tgatgggacg ccattcggac ggggaattcc aaatcaattt
     3721 caacagtaac gcttttatca ataccctcaa atcctacaaa atgctgggca tgttcccatt
     3781 gagcgggctc attgctccca ccgaggtatc tcccattgac tgcgtggccc gtgccgtaca
     3841 cgtactttcc aaaacacctt cagaagtggt actgttgcac gcctacaaca acaaccggct
     3901 tgacatggca agcatgatct tcgcgatgaa ggagtatggc tttgatattg agctggtttc
     3961 cgatgagcgc ttcaggcagc gctttaatga aatgatgaag aatcctgcca tgagcgaata
     4021 cctggggggc ttgctccact atggcattga tacggaaaaa gtacccgttc ccgatgacaa
     4081 cagctacact accttattgc tttaccgcaa caatgtacgt tggccgctgg ccgatgaagg
     4141 gtactcactc aagctgataa aaatgcttga cgggatggga ttttttgtca attgaaccac
     4201 cctgtacgaa aagtagtttt caaaaagaca gagaaaagtt ataactttat tccacaaacc
     4261 tgaattgtat gttatgatgg ttcacaatcc atggcacagt gttgaacccg atcttgaagg
     4321 attcgaggtc aatgcgctca ttgaaatcag caatggaagc cgcgcaaagt acgaactgga
     4381 caaggtaacc ggcctgttgc ggctggacag ggtattgtat tcagccgtat attatccggc
     4441 caattacggt ttcatacccc ggacctttgc caaagacgat gacccgctgg acgttctggt
     4501 actgtcacag attcccatcc agcccctttg tatagtcagg gttaaaatca ttggtgtgat
     4561 gcagatgatt gaccagggca agcccgatga taaactcatt tcggtggcat gtcacgacaa
     4621 aagcgtcagc catttagaag aaatcaaagg catgcctccc atttttgatt ccgaactcaa
     4681 gcaattcttt gaagagtaca aacgcctgga aaacaagaca gtcctggtag aagaattcgc
     4741 agacaggatc catgcccttg aaatcctgga agattccctg caacggtacc gcgaattgta
     4801 ccagtaatta ccccagcaat tggttcttcg tcaatttcgg tgcatgagaa ggtgttccca
     4861 aaaaggctaa aaaattagct taaaacgctg aatatcaata aaataaactt gcaaattcga
     4921 gatattgtta ttaacttaaa gtgctgaata taagtacttt aaacatgctc aaaactgcta
     4981 acgaaaacaa gaataccaat atttttctca aagacaaaat cctacgaggt gtgacaggat
     5041 ataagcaaat aagattcatt gaaggatata ttaataacga gactgtggat gttacagcaa
     5101 gactaacact gtcctatgca agatgtccct tatgcggaaa gaagagtcat tctgttcatt
     5161 caacttatga acgccaacta atggatttgc caattcatgg aaaacggatg aacataagac
     5221 tattagcaag aaaattcaga tgccgaaatc ttaagtgccg ccaaattgta ttttcagaac
     5281 agccaactgg aattgcagaa agatattcca gaaaaaccat tgttgcaaaa tcaaaattac
     5341 aatcaatcct gatagaaatg tctgcgacga agggagcctt aatagtttcc tcaatgggga
     5401 tgtcacaaag cgcatccacg tgtctaaggt taatcaaatc aattgagatc aaggttaaca
     5461 aagcatcggt caaacacatc tgcatagatg attttgcata taggaaaggc aacaagtatg
     5521 gcaccatcat cattgatgcc gacacaagca aaacgattgc actaataaat agcagagaaa
     5581 cggatcatgt tgcaacagcg ttgaaagcct atccaaatgt tcagacagtt tcccgtgata
     5641 ggtcttctgc atatgcaaat gcaattaagc aaggaatacc ggaagcggct caaattgcgg
     5701 ataaattcca tcttgtcaag aattgtggag aacatatgga agcacaacta aaaaaatcat
     5761 ttaatcaaat aaaggatgaa ctatccaagc agataagtga gcctttgcca ccccccgttt
     5821 catcataccc aacgatagat aatccggaac ctgtacaatt atcttcaagg cccccttcgg
     5881 aaaaacaaag atatctattt aaacaggtcc aaaagctaaa taaagaaaat tattccgagc
     5941 gtgaaatagt caggcatctt catatatcaa ggggcttagt gcgtaaatat ttgtcattga
     6001 acgagccaca aggtaataag attgctttta ggaatgatta ttcattgttc ctgcccattg
     6061 tccagaacgg gatccataat aaagcccgta tcagtgaaat ctatagaaat tccgtaaatg
     6121 ccggtctgtg ctgttcctat atcgcattcc tgaattggat gagaaccgta ttccctgaat
     6181 ataagacatt caaaggaaaa gccacaagaa acagtcgagt agacagtaca ggttatgaca
     6241 gaacaaaatc tgtactcaaa gcgctgtctt catataagct caatatttac attgccaatc
     6301 cggaatgggg aataaataaa aagactggcc aatgcagcaa agagaatata caaatgaatg
     6361 aaattataca gtcatcaagc acccttttaa aactacgtga gttctgtgtg tctttcaagg
     6421 ccgtgattgc tggaaattca atatcggata ttgtcgcctg gatagaaaaa tataaaaatg
     6481 aatcttttgc tcatttaaga acgtttgcaa cagggcttat aaaggatata gatgctgtta
     6541 aaaacgctat tttatatccc tacaataatg gactggccga gggattgaac aataagttga
     6601 aagcgctaaa aagaggcatg tacggaagag ccggcaatag gctcattgag ataaaaatgg
     6661 tagcttcctt gacgggttag attgcaccaa aattgacgaa gaacccagca attgtaccag
     6721 cagttgcgcc agcaattgta caaccggggg aggtacttac cacctccccc tcaaaatcgc
     6781 tgctttacgg cttaatacat caagagagcg cggctataca cctgataatc tcttgcggcg
     6841 tatgggccat ctgatccgga ttcaaggtag agaggatttc ccggttgttc atgccccagg
     6901 tgaccgacac aatgggtatg cccactttcc ggcaggcttc tatatcccgc gtctcgtccc
     6961 cgacataaat ggccgaggcg ggatgaattt tcttattggc taacattctt ttgaatacct
     7021 tgtcttttcc aaaaagactc ttcccgctgt aaacgaagtc aaacagacta ttcatgccgt
     7081 tgttttccag gaacaggacc acgttgggcc tggcgttgga agttatgatt cccagccggt
     7141 aatccttgtc tctaagcgtt gtgaggacct ctttcatacc ctcaaagggc ttcatttgcg
     7201 gtacatgact aaggatctct ttccttatgc ggattgttat caggccgagt ttgtgggcag
     7261 acatgttgta ttgtctgagc aaatcctgcg gtttcccagc ggcaatgatt tgtctgtctt
     7321 ccggtttcag gggcttacag ccatattcgc cggcaatgct gttgtacagg gtaaagacca
     7381 ggtcaaaggt atcggccagg gtcccgtcaa agtcaaaaag gatgtattgg atggttttca
     7441 ctgcttctaa tttggtaaca aaaatacaac atttagccca gaagatttca tttgacgttc
     7501 actcatctgg catcttgttg tttatcactt tcggttttgt cgtaggaaag aactgccaga
     7561 taacaaataa ttcatacatt taaagtgaat tcgatgcagt aaaactcctt tttattcatt
     7621 taggcagata tgaaaaaatt gattttctgg ttttttttat ccagttcctg tttggtatac
     7681 gctcaaaaac aaaccgaggt ttatttaata ggcagtgttc atgccatgca cctgaatcag
     7741 gaatatcatt actccctgac cgatctgatg gctcaaattc aaaagattaa acccgacata
     7801 gtctgcgggg aaataacccc tgatgcatac aactcggttt ttgaaggata ttttcctccc
     7861 gaggcggcca tgcttgccca gatggcgccg gtggtgggtt accaattcgt cccggttgac
     7921 tggcgggccg attttatttt acagcaggaa gctgaacggc actatcctcg gaagatcaaa
     7981 gatgaaataa acaaagttgc aagttgggca aatacctatg agaattccgg attaccatcg
     8041 ctatacgacc atattcacag taaaagcacc ctgaagacga ttgaccaggt ttatgaaatg
     8101 atcatcagcg attctatcgc aaacagggca catggtttct ggcgtgaaag aaacagggcc
     8161 atagtgaaaa acggaatgag ttccctgcat gatgtcggca gggtggtttt tgtttttggt
     8221 gtagaccaca tgtcaaggct tataagagaa ttggaaaact acgatgttca aatactgatc
     8281 cctgaaagga tgtttgatgc tgatcattct gtccagatta cagaagatgt ttgcaaaaga
     8341 tgggcactca gtctggaaaa tctgcaattg atcaaagaca ggaaaataga agtaacccca
     8401 ggctattacc aaaaaatcat taatagcaac cgaataacag aattgcaaag attcctggat
     8461 tattatagta caccgtatgc caatggccag gacttggaat acattctggc gaaagaaagt
     8521 attagagacc tggactctat tgtcactcca aagggaatat gggaaaattt tgaactggcc
     8581 attgggggga tcaaccaatc tgtatacaca aggggtaatg acagggataa tcctgtaata
     8641 atttttgtgc atggcggccc ttcatcacca atgtctccgg ttatgtggat gtatcagaga
     8701 cctctggagg aatttttcac tatggtgaac tatgaccagc gaggtgcagg gaaaacatac
     8761 ttacgaaatg atacgacact gctatctaat acgatgacca ttgaatggtt tgtcaacgat
     8821 ttgattgcat tgacagattc aataaggcag cggtattgca aggagaaagt aatactcatg
     8881 gcacatagct ggggaactgt agtgtccatg aatgcagtct tgaaaagacc ggatttgtat
     8941 tatgcttatg ttggtctagg ccaggtaatc aatttcatgg acaatgaacg tttatgcttt
     9001 gaatttggtt tgaatcaagc cagaagaagc aatgatagca ctgcaataaa agaaatggaa
     9061 tctgttgcac catacccggg agacaatccg gttaccgatg gccgtattag tattgtcaga
     9121 aaatgggctc agtattatgg gggcttcacg gcgtatcgca aggttccaaa attttactat
     9181 tatgctccgc ttctatcgcc ggattattca tccctggaaa gagaagctat tgatggcggt
     9241 gctcttttta cgatcccaaa gattttgccc gaactattga aagtcgattt taaacacgtc
     9301 gataaatttc caataccggt attcatgttt atgggaagac acgattttac caccccggca
     9361 gaacccgtac tggattggat acatagagtt aaagctccac taaagcgtgc catatggttt
     9421 gaaaattcag gacatttgat accactggaa gagcctggaa aaatgttggt aaccttatta
     9481 catgaggtca gaccattggc agacaacagt aatagtaaaa gataataa
//
