3300010396_63 - 12 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

c00005_3300010.. (original name was: 3300010396.a:Ga0134126_10000206)

Region	Type	From	To	Most similar known cluster		Similarity
Region 5.1	NRPS	1	42,289

c00008_3300010.. (original name was: 3300010396.a:Ga0134126_10011409)

Region	Type	From	To	Most similar known cluster		Similarity
Region 8.1	NRPS	1	11,212

c00014_3300010.. (original name was: 3300010396.a:Ga0134126_10024722)

Region	Type	From	To	Most similar known cluster		Similarity
Region 14.1	NRPS-like	1	7,626

c00019_3300010.. (original name was: 3300010396.a:Ga0134126_10000451)

Region	Type	From	To	Most similar known cluster		Similarity
Region 19.1	NRPS	1	22,248

c00020_3300010.. (original name was: 3300010396.a:Ga0134126_10000548)

Region	Type	From	To	Most similar known cluster		Similarity
Region 20.1	NRPS	1	32,586

c00060_3300010.. (original name was: 3300010396.a:Ga0134126_10000902)

Region	Type	From	To	Most similar known cluster		Similarity
Region 60.1	thiopeptide	1,095	30,025

c00062_3300010.. (original name was: 3300010396.a:Ga0134126_10000088)

Region	Type	From	To	Most similar known cluster		Similarity
Region 62.1	NRPS	15,757	65,341

c00068_3300010.. (original name was: 3300010396.a:Ga0134126_10000228)

Region	Type	From	To	Most similar known cluster		Similarity
Region 68.1	NRPS	1	22,596

c00086_3300010.. (original name was: 3300010396.a:Ga0134126_10000330)

Region	Type	From	To	Most similar known cluster		Similarity
Region 86.1	T1PKS,NRPS	1	40,697
Region 86.2	bacteriocin	45,091	55,912

c00088_3300010.. (original name was: 3300010396.a:Ga0134126_10004574)

Region	Type	From	To	Most similar known cluster		Similarity
Region 88.1	NRPS	1	17,300

c00093_3300010.. (original name was: 3300010396.a:Ga0134126_10000937)

Region	Type	From	To	Most similar known cluster		Similarity
Region 93.1	butyrolactone	24,149	34,799

Region	Type	From	To	Similarity
Region 5.1	NRPS	1	42,289
Region 8.1	NRPS	1	11,212
Region 14.1	NRPS-like	1	7,626
Region 19.1	NRPS	1	22,248
Region 20.1	NRPS	1	32,586
Region 60.1	thiopeptide	1,095	30,025
Region 62.1	NRPS	15,757	65,341
Region 68.1	NRPS	1	22,596
Region 86.1	T1PKS,NRPS	1	40,697
Region 86.2	bacteriocin	45,091	55,912
Region 88.1	NRPS	1	17,300
Region 93.1	butyrolactone	24,149	34,799

No secondary metabolite regions were found in these records:: c00001_3300010.. (original name was: 3300010396.a:Ga0134126_10085334); c00002_3300010.. (original name was: 3300010396.a:Ga0134126_10003967); c00003_3300010.. (original name was: 3300010396.a:Ga0134126_10002124); c00004_3300010.. (original name was: 3300010396.a:Ga0134126_10000667); c00006_3300010.. (original name was: 3300010396.a:Ga0134126_10000256); c00007_3300010.. (original name was: 3300010396.a:Ga0134126_10001196); c00009_3300010.. (original name was: 3300010396.a:Ga0134126_10000226); c00010_3300010.. (original name was: 3300010396.a:Ga0134126_10000661); c00011_3300010.. (original name was: 3300010396.a:Ga0134126_10026320); c00012_3300010.. (original name was: 3300010396.a:Ga0134126_10002493); c00013_3300010.. (original name was: 3300010396.a:Ga0134126_10000317); c00015_3300010.. (original name was: 3300010396.a:Ga0134126_10002553); c00016_3300010.. (original name was: 3300010396.a:Ga0134126_10000807); c00017_3300010.. (original name was: 3300010396.a:Ga0134126_10079197); c00018_3300010.. (original name was: 3300010396.a:Ga0134126_10001777); c00021_3300010.. (original name was: 3300010396.a:Ga0134126_10001892); c00022_3300010.. (original name was: 3300010396.a:Ga0134126_10000760); c00023_3300010.. (original name was: 3300010396.a:Ga0134126_10003985); c00024_3300010.. (original name was: 3300010396.a:Ga0134126_10045405); c00025_3300010.. (original name was: 3300010396.a:Ga0134126_10004014); c00026_3300010.. (original name was: 3300010396.a:Ga0134126_10017595); c00027_3300010.. (original name was: 3300010396.a:Ga0134126_10109872); c00028_3300010.. (original name was: 3300010396.a:Ga0134126_10005680); c00029_3300010.. (original name was: 3300010396.a:Ga0134126_10000423); c00030_3300010.. (original name was: 3300010396.a:Ga0134126_10001128); c00031_3300010.. (original name was: 3300010396.a:Ga0134126_10083430); c00032_3300010.. (original name was: 3300010396.a:Ga0134126_10000142); c00033_3300010.. (original name was: 3300010396.a:Ga0134126_10031235); c00034_3300010.. (original name was: 3300010396.a:Ga0134126_10002171); c00035_3300010.. (original name was: 3300010396.a:Ga0134126_10040658); c00036_3300010.. (original name was: 3300010396.a:Ga0134126_10000074); c00037_3300010.. (original name was: 3300010396.a:Ga0134126_10024502); c00038_3300010.. (original name was: 3300010396.a:Ga0134126_10003954); c00039_3300010.. (original name was: 3300010396.a:Ga0134126_10027374); c00040_3300010.. (original name was: 3300010396.a:Ga0134126_10001294); c00041_3300010.. (original name was: 3300010396.a:Ga0134126_10001847); c00042_3300010.. (original name was: 3300010396.a:Ga0134126_10129088); c00043_3300010.. (original name was: 3300010396.a:Ga0134126_10025413); c00044_3300010.. (original name was: 3300010396.a:Ga0134126_10007734); c00045_3300010.. (original name was: 3300010396.a:Ga0134126_10052104); c00046_3300010.. (original name was: 3300010396.a:Ga0134126_10001577); c00047_3300010.. (original name was: 3300010396.a:Ga0134126_10002038); c00048_3300010.. (original name was: 3300010396.a:Ga0134126_10000575); c00049_3300010.. (original name was: 3300010396.a:Ga0134126_10014281); c00050_3300010.. (original name was: 3300010396.a:Ga0134126_10003159); c00051_3300010.. (original name was: 3300010396.a:Ga0134126_10000346); c00052_3300010.. (original name was: 3300010396.a:Ga0134126_10018306); c00053_3300010.. (original name was: 3300010396.a:Ga0134126_10001866); c00054_3300010.. (original name was: 3300010396.a:Ga0134126_10052604); c00055_3300010.. (original name was: 3300010396.a:Ga0134126_10000171); c00056_3300010.. (original name was: 3300010396.a:Ga0134126_10001166); c00057_3300010.. (original name was: 3300010396.a:Ga0134126_10023694); c00058_3300010.. (original name was: 3300010396.a:Ga0134126_10003625); c00059_3300010.. (original name was: 3300010396.a:Ga0134126_10009782); c00061_3300010.. (original name was: 3300010396.a:Ga0134126_10003670); c00063_3300010.. (original name was: 3300010396.a:Ga0134126_10047176); c00064_3300010.. (original name was: 3300010396.a:Ga0134126_10000267); c00065_3300010.. (original name was: 3300010396.a:Ga0134126_10004535); c00066_3300010.. (original name was: 3300010396.a:Ga0134126_10000754); c00067_3300010.. (original name was: 3300010396.a:Ga0134126_10013363); c00069_3300010.. (original name was: 3300010396.a:Ga0134126_10013244); c00070_3300010.. (original name was: 3300010396.a:Ga0134126_10000113); c00071_3300010.. (original name was: 3300010396.a:Ga0134126_10025212); c00072_3300010.. (original name was: 3300010396.a:Ga0134126_10000234); c00073_3300010.. (original name was: 3300010396.a:Ga0134126_10001143); c00074_3300010.. (original name was: 3300010396.a:Ga0134126_10057087); c00075_3300010.. (original name was: 3300010396.a:Ga0134126_10000903); c00076_3300010.. (original name was: 3300010396.a:Ga0134126_10017730); c00077_3300010.. (original name was: 3300010396.a:Ga0134126_10004958); c00078_3300010.. (original name was: 3300010396.a:Ga0134126_10000494); c00079_3300010.. (original name was: 3300010396.a:Ga0134126_10004673); c00080_3300010.. (original name was: 3300010396.a:Ga0134126_10022320); c00081_3300010.. (original name was: 3300010396.a:Ga0134126_10011450); c00082_3300010.. (original name was: 3300010396.a:Ga0134126_10016688); c00083_3300010.. (original name was: 3300010396.a:Ga0134126_10000431); c00084_3300010.. (original name was: 3300010396.a:Ga0134126_10004411); c00085_3300010.. (original name was: 3300010396.a:Ga0134126_10021079); c00087_3300010.. (original name was: 3300010396.a:Ga0134126_10017671); c00089_3300010.. (original name was: 3300010396.a:Ga0134126_10008550); c00090_3300010.. (original name was: 3300010396.a:Ga0134126_10011043); c00091_3300010.. (original name was: 3300010396.a:Ga0134126_10021192); c00092_3300010.. (original name was: 3300010396.a:Ga0134126_10085630); c00094_3300010.. (original name was: 3300010396.a:Ga0134126_10019559); c00095_3300010.. (original name was: 3300010396.a:Ga0134126_10031742); c00096_3300010.. (original name was: 3300010396.a:Ga0134126_10039465)

Compact view

c00005_3300010.. - Region 1 - NRPS

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Location: 1 - 42,289 nt. (total: 42,289 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 42289:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (thr - thr)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg5_10

Search NORINE for peptide: strict or relaxed

AMP-binding (522..957): thr

NRPSPredictor2: thr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: thr
Single AA prediction:: thr

Stachelhaus prediction details:

Stachelhaus sequence:: DFWNIGMiHK
Nearest Stachelhaus code:: thr
Stachelhaus code match:: 90% (moderate)

AMP-binding (2159..2609): thr

NRPSPredictor2: thr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: thr
Single AA prediction:: thr

Stachelhaus prediction details:

Stachelhaus sequence:: DFWNIGMVHK
Nearest Stachelhaus code:: thr
Stachelhaus code match:: 100% (strong)

c00008_3300010.. - Region 1 - NRPS

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Location: 1 - 11,212 nt. (total: 11,212 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 11212:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (ser)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg8_1

Search NORINE for peptide: strict or relaxed

AMP-binding (521..955): ser

NRPSPredictor2: ser

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: ser
Single AA prediction:: ser

Stachelhaus prediction details:

Stachelhaus sequence:: DVWHFSLVDK
Nearest Stachelhaus code:: ser
Stachelhaus code match:: 100% (strong)

c00014_3300010.. - Region 1 - NRPS-like

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Location: 1 - 7,626 nt. (total: 7,626 nt) Show pHMM detection rules used

Region on contig edge.

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 7626:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (val)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg14_1

Search NORINE for peptide: strict or relaxed

AMP-binding (1..359): val

NRPSPredictor2: val

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: val

Stachelhaus prediction details:

Stachelhaus sequence:: DAFWlGGTFK
Nearest Stachelhaus code:: val
Stachelhaus code match:: 90% (moderate)

c00019_3300010.. - Region 1 - NRPS

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Location: 1 - 22,248 nt. (total: 22,248 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

c00020_3300010.. - Region 1 - NRPS

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Location: 1 - 32,586 nt. (total: 32,586 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 32586:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (phe - D-ser)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg20_4

Search NORINE for peptide: strict or relaxed

AMP-binding (894..1305): phe

NRPSPredictor2: phe

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: phe, trp, phg, tyr, bht
Small clusters prediction:: phe, trp
Single AA prediction:: phe

Stachelhaus prediction details:

Stachelhaus sequence:: DAWTVAAVCK
Nearest Stachelhaus code:: phe
Stachelhaus code match:: 100% (strong)

AMP-binding (1989..2410): ser

NRPSPredictor2: ser

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: ser
Single AA prediction:: ser

Stachelhaus prediction details:

Stachelhaus sequence:: DVWHFSLVDK
Nearest Stachelhaus code:: ser
Stachelhaus code match:: 100% (strong)

c00060_3300010.. - Region 1 - thiopeptide

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Location: 1,095 - 30,025 nt. (total: 28,931 nt) Show pHMM detection rules used

thiopeptide: ((YcaO or TIGR03882) and ((thio_amide and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N or PF07366 or PF06968 or PF04055) or thiostrepton)

Legend:

core biosynthetic genes

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Thiopeptides

Thiopeptide predictions

No core peptides found.

Thiopeptides

Core peptide predictions

No core peptides found.

c00062_3300010.. - Region 1 - NRPS

Download region GenBank file

Location: 15,757 - 65,341 nt. (total: 49,585 nt) Show pHMM detection rules used

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 15756 - 65341:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (thr - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg62_33

Search NORINE for peptide: strict or relaxed

AMP-binding (460..875): thr

NRPSPredictor2: thr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: thr
Single AA prediction:: thr

Stachelhaus prediction details:

Stachelhaus sequence:: DFWNIGMVHK
Nearest Stachelhaus code:: thr
Stachelhaus code match:: 100% (strong)

AMP-binding (1526..1939): X

NRPSPredictor2: glu, gln

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: glu, gln
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAehVGEVtK
Nearest Stachelhaus code:: tyr
Stachelhaus code match:: 70% (weak)

c00068_3300010.. - Region 1 - NRPS

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Location: 1 - 22,596 nt. (total: 22,596 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

c00086_3300010.. - Region 1 - NRPS,T1PKS

Download region GenBank file

Location: 1 - 40,697 nt. (total: 40,697 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 40697:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (D-X - X - ohmal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg86_10

Search NORINE for peptide: strict or relaxed

AMP-binding (470..903): X

NRPSPredictor2: val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: phe, trp, phg, tyr, bht
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DSafvAEVCK
Nearest Stachelhaus code:: his
Stachelhaus code match:: 70% (weak)

AMP-binding (2148..2562): X

NRPSPredictor2: val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAyFyGqVcK
Nearest Stachelhaus code:: leu
Stachelhaus code match:: 60% (weak)

PKS_AT (3304..3597): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 79.2%; inactive: 66.7%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 102.6
inactive: 77.7
Methoxymalonyl-CoA: 42.1
Methylmalonyl-CoA: 28.5
Propionyl-CoA: 25.2
trans-1,2-CPDA: 0.0
fatty_acid: 0.0
Isobutyryl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

c00086_3300010.. - Region 2 - bacteriocin

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Location: 45,091 - 55,912 nt. (total: 10,822 nt) Show pHMM detection rules used

bacteriocin: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03603 or TIGR03604 or TIGR03651 or TIGR03678 or TIGR03693 or TIGR03798 or TIGR03601 or TIGR03602 or TIGR03795 or TIGR03793 or TIGR03975 or DUF692 or TIGR01193)

Legend:

core biosynthetic genes

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Gene details

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c00088_3300010.. - Region 1 - NRPS

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Location: 1 - 17,300 nt. (total: 17,300 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 17300:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (asn)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg88_2

Search NORINE for peptide: strict or relaxed

AMP-binding (466..890): asn

NRPSPredictor2: asn

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: asp, asn
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DLTKIGEVGK
Nearest Stachelhaus code:: asn
Stachelhaus code match:: 100% (strong)

c00093_3300010.. - Region 1 - butyrolactone

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Location: 24,149 - 34,799 nt. (total: 10,651 nt) Show pHMM detection rules used

butyrolactone: AfsA

Legend:

core biosynthetic genes

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Gene details

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