LOCUS       c00008_3300010..       11212 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300010396.a:Ga0134126_10011409.
ACCESSION   c00008_3300010..
VERSION     c00008_3300010..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 21:36:01
            Original ID  :: 3300010396.a:Ga0134126_10011409
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 11212
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..11212
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1:3811](-)"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(2..3811)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..11212
                     /SMILES="NC(CO)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..11212
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="(cds(Condensation and (AMP-binding or A-OX)) or
                     (Condensation and AMP-binding))"
                     /tool="antismash"
     CDS             complement(2..3811)
                     /NRPS_PKS="Domain: AMP-binding (521-955). E-value:
                     1.4e-110. Score: 361.4. Matches aSDomain:
                     nrpspksdomains_ctg8_1_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (1067-1133). E-value: 3.4e-15.
                     Score: 47.8. Matches aSDomain: nrpspksdomains_ctg8_1_PCP.1"
                     /NRPS_PKS="type: NRPS-like protein"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1228:methionyl-tRNA formyltransferase (Score: 73.6;
                     E-value: 2.3e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_1"
                     /sec_met_domain="Condensation (E-value: 2e-21, bitscore:
                     65.3, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 4.7e-123, bitscore:
                     399.8, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 4.5e-13, bitscore:
                     38.8, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLVSKNAVIFGETGLTISCIEHLLHNNWNINAVLTQDDSVSNWCK
                     ERSIRCLNMEQSFELTSGSKGCFVFSIINPYILSTKLISHIDPIKAINYHDSLLPKYAG
                     VNSTTWAILGNEQFHGITWHEIIAGIDEGDIYYQAKIPIGDVETAFSLNLKCTDAALIG
                     FKQLIADIEHDKLIGIKQDLSKKTYFGRDYLPDNYAYLNTTDSIFCINKLLNGLNFGDG
                     YVNPVTIVKVKINGLSYILEKKIQQENIDVIDSSTCILRNMYGEKVQKSFKITQIQQCV
                     LSVADISNCRKLKREEFNIHNRVSELLKESQAQTGLLSYSMLSNSRQDIKLDIKLSIDM
                     LSLFLSIILSRLNSNETFIKIYHKNINYRSNLTKKITENISILKLCQDNLELRYIEMTQ
                     KINEAIDNSIHIFKDFGYRYKQNLCSELAITDNYSGEIDNHKVVFVINRKEISVKCYKK
                     DMDFIKMLIKTIDMLFAGHKEAQRADILVKNLPLLSKEDYQKVVYDWNKTEKEYPQEKT
                     IHQLFEEQVAKTSNNIAIVYEDIKLTYKELNERSNQLANYLRETYQIKGDDLIALCLNR
                     SEYMLIAILGVLKSGAAYVPIDPDFPIERIDYILKDTRAKILITDTKAASVVQKSLQAL
                     RSNVRQSKNNRSPSIICDDVIIDDKEFAQGLKKYPISDPKLNITSKNLAYVIYTSGTTG
                     VPKGVMLQHQGVVNRIQWMNDKYPLVKYDKMLQKTPYIFDVSVWELFWGNWYGATIIFA
                     KPDGHKSPEYLVKLVEQNEITILHFVPSMLRIFTQTLEAMLNSSNINLNMLRHVFCSGE
                     SLPLSYAKDLHRQLPAVRIHNLYGPTEATVDILYYDFSANGIDMVPIGRPISNTTCYIL
                     DNNLKPLPIGSTGEIYAGGVGLALGYLNLPDLTNESFISNPFQTEKERQLGINARIYKT
                     GDLARYLLDGNIEFIGRNDFQIKVRGFRIELGEIENILLSYPQIEHCVVLSKKPSDIND
                     NQLSENMHLMAYYIADKELDKTEILAYMSKKLPDYMLPDMFIRIERLPLTVNGKLDINA
                     LPYPEFVTKGEYIAPRNELEQKICMIYADVLKLPLDKVGITNDFFRLGGNSLLVIKLAN
                     KLSSNLKINVTMVTLLKCKTIFAILNQIKFGNTTPPKIPKLKVQNNSRYPLSFAQERLW
                     FIDRYENGSNVYNIPLVVEINSKVDLAILKQAINSIIKRHEILHSLIKTDEFGDSYQKI
                     CNLKERPLIFDEQTVSSKLKLNQLINQSVNHVYNLNEEYPIKISI"
     CDS_motif       complement(179..283)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg8_1_0005"
                     /evalue="2.20E-13"
                     /label="C2_LCL_024-062"
                     /locus_tag="ctg8_1"
                     /protein_end="1211"
                     /protein_start="1176"
                     /score="42.6"
                     /tool="antismash"
                     /translation="VYNIPLVVEINSKVDLAILKQAINSIIKRHEILHSL"
     aSDomain        complement(413..610)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg8_1_PCP.1"
                     /evalue="3.40E-15"
                     /label="ctg8_1_PCP.1"
                     /locus_tag="ctg8_1"
                     /protein_end="1133"
                     /protein_start="1067"
                     /score="47.8"
                     /tool="antismash"
                     /translation="EQKICMIYADVLKLPLDKVGITNDFFRLGGNSLLVIKLANKLSSN
                     LKINVTMVTLLKCKTIFAILNQ"
     aSModule        413..2248
                     /complete
                     /domains="nrpspksdomains_ctg8_1_AMP-binding.1"
                     /domains="nrpspksdomains_ctg8_1_PCP.1"
                     /locus_tags="ctg8_1"
                     /monomer_pairings="ser -> ser"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(917..982)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg8_1_0004"
                     /evalue="9.00E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg8_1"
                     /protein_end="965"
                     /protein_start="943"
                     /score="36.9"
                     /tool="antismash"
                     /translation="FIGRNDFQIKVRGFRIELGEIEN"
     aSDomain        complement(947..2248)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg8_1_AMP-binding.1"
                     /evalue="1.40E-110"
                     /label="ctg8_1_AMP-binding.1"
                     /locus_tag="ctg8_1"
                     /protein_end="955"
                     /protein_start="521"
                     /score="361.4"
                     /specificity="consensus: ser"
                     /tool="antismash"
                     /translation="FEEQVAKTSNNIAIVYEDIKLTYKELNERSNQLANYLRETYQIKG
                     DDLIALCLNRSEYMLIAILGVLKSGAAYVPIDPDFPIERIDYILKDTRAKILITDTKAA
                     SVVQKSLQALRSNVRQSKNNRSPSIICDDVIIDDKEFAQGLKKYPISDPKLNITSKNLA
                     YVIYTSGTTGVPKGVMLQHQGVVNRIQWMNDKYPLVKYDKMLQKTPYIFDVSVWELFWG
                     NWYGATIIFAKPDGHKSPEYLVKLVEQNEITILHFVPSMLRIFTQTLEAMLNSSNINLN
                     MLRHVFCSGESLPLSYAKDLHRQLPAVRIHNLYGPTEATVDILYYDFSANGIDMVPIGR
                     PISNTTCYILDNNLKPLPIGSTGEIYAGGVGLALGYLNLPDLTNESFISNPFQTEKERQ
                     LGINARIYKTGDLARYLLDGNIEFIGRNDFQIKVRG"
     CDS_motif       complement(1088..1177)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg8_1_0003"
                     /evalue="5.10E-13"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg8_1"
                     /protein_end="908"
                     /protein_start="878"
                     /score="41.2"
                     /tool="antismash"
                     /translation="PIGSTGEIYAGGVGLALGYLNLPDLTNESFI"
     CDS_motif       complement(1703..1762)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg8_1_0002"
                     /evalue="1.70E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg8_1"
                     /protein_end="703"
                     /protein_start="683"
                     /score="32.7"
                     /tool="antismash"
                     /translation="AYVIYTSGTTGVPKGVMLQHQ"
     CDS_motif       complement(2018..2059)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg8_1_0001"
                     /evalue="1.30E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg8_1"
                     /protein_end="598"
                     /protein_start="584"
                     /score="18.3"
                     /tool="antismash"
                     /translation="LGVLKSGAAYVPIDP"
     CDS             complement(3855..4214)
                     /locus_tag="ctg8_2"
                     /transl_table=11
                     /translation="MNGIIIFFIATSSTVFSQICWKISSRQVLQLSDGHSLLLKQFTNL
                     WFIVGWVFYLLATFLWVYLLSKYEYSKIYPIYVGVCIVLSLMVGFIFFKENTGMFYKTV
                     GSALIICGITLITRS"
     CDS             complement(4732..6081)
                     /locus_tag="ctg8_3"
                     /transl_table=11
                     /translation="MQENNHIEFKRELSDSLEKEVIAFLNYKDGGIIYVGIDKTGTIVG
                     VINPDDTQLKIKDRIKNNISPSTMGLFDVVTEMQEGKYVVKVIVASGSEKPYYLSKMGM
                     STRGCYIRIGSAAEPMTERMIEDLFARRIRNSIGTIRSRYQDLTFEQLRIYYSEAKLDL
                     NGQFAKNLELLTEDGKYNYAAYMLSDMNGVSIKVAKYSGLNRVDLIENEEYGMCCLIKA
                     TKSVLEKLKVENKTFAKITDTVRKERKLLDPTALREAIINAIIHNDYSNEIPPKFELFA
                     DRLEITSAGTLPPGFNEEDFFLGYSVPQNKELMRVFKDLDLVEHMGSGVPRILESYPTT
                     VFHFSRNFIRVTLPFDKGFRQASDQASDQASDQASDQASDQASKNEASILQFCKIPRSA
                     QEIMQYLGLKHKTFFRNTILSPLIAEGKLALTTPEIPKSPKQKYVTVKNK"
     CDS             complement(6170..7051)
                     /locus_tag="ctg8_4"
                     /transl_table=11
                     /translation="MGEKESIFEYLETIAELIPAAFFWLDPKGRAMGCNTLSMKGVGAL
                     NKADIIGQTPYEMYKDKFIADRLLKIVNEVIQTGKILQTEDTTIDVVTGKVKHFAATRA
                     PLRNKHGKIIGVVGTSIEITAHKEAERLRLENIKLEAQNKLNQVFLEKLAAETEAEHLR
                     LENEAYLVQKKEQAKFLTFIDKIQRDIQNYKIEALTEQIGIKPNISSSDRQIRLTKREL
                     DVLYYLSLNKSPKDIAQIITIIEDKPVSDSTINAIINKKLYPKFEVFNIGQLVEKAIML
                     NQIPFLLDDSSS"
     CDS             complement(7188..7850)
                     /locus_tag="ctg8_5"
                     /transl_table=11
                     /translation="MFKKCMFIFLICLFAIVYADSGIGNVGSVVAIPSSKNMEGASLAP
                     AMDVKYAVYNYQMKPAEFAKFLEINNLSKTANLTSSINIVSLTALQKGELDTLSQKLAK
                     EFSNKFSGGSTCRVNNDLCAGGSMGISDIPDSKTGKPATASKISIFFKIFNKNKEFSAK
                     VISDNIIDNHATTLNLISLKSEAMLSDIKNKNYVMISQISKNDILYGQIIQISFSSK"
     CDS             8832..9536
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_6"
                     /sec_met_domain="PF00561 (E-value: 1.5e-11, bitscore: 33.5,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKKILFFPGGWSKAEDSLAPQIEYFKKLPGYDVICPNIHQFDTV
                     TKMSDYVLRSYNDVHAVVGLSMGGFIVQDILTKQPTFSSKAVIMGSFAHAQFDEAKIFF
                     RQLINQVKSNGLEEICHLYAKDMLSDNSFLNKSDLVATVIQIPQNLGQEQCINHSEACI
                     TWDGCLDSLKQIKSKVLILAAELDKATPISGHRQLHELIANSSLQIVPNSGHFMTLEQP
                     EIVNKFMHEWLL"
     CDS             9718..10584
                     /locus_tag="ctg8_7"
                     /transl_table=11
                     /translation="MSRYLDPKADVVFKKIFGDHPHLLKSFLNAVLPLSTEGQIVELEY
                     LPNEQVPHIPAFKRTIADVKCKDINGRVFIVEMQIDWTDGFKQRLLFSTSQAVVKQLEK
                     GESYRLLQPVYGLGIVADIFDKTNPEWYHHYQLVKNGNSGCDVIEHLQLVFIELPKFPV
                     QSPEEKRLRLLWLRFLREIDEKTINVSQELLDVPEISEAIVLAEGAAYTPGELNAYETY
                     WDAVRTEKTLMEGRYAEGEAKGRAEGIEQRTIEMAKAMLLQGISVDIAANVSGLPRETL
                     AKLIEKK"
     CDS             complement(10909..11211)
                     /locus_tag="ctg8_8"
                     /transl_table=11
                     /translation="AIKDDFKEKYIKLAAERLNFLKMSLEEQAYYMRYKIEMIDVREEF
                     HTQYIKGEAKGKVEGKVEGKMEMAEALLLRGISLDVVANVSGLSQETLAKLASKK"
ORIGIN
        1 agatggatat ttttattgga tattcttcat ttaagttata aacatggttt acagattggt
       61 taattagttg gtttaatttc agtttacttg atacagtttg ttcatcaaat attaatggtc
      121 tttctttcaa attacatatt ttttggtaac tatcaccaaa ctcgtcggtt ttaattaaac
      181 tatgtaatat ttcatgacgt ttaataatag aattaatcgc ttgttttaag atagctaaat
      241 caactttact attaatttca actactaatg gaatattata tacattactt ccattctcat
      301 atctatcaat aaaccatagg cgttcctgag caaaagataa tggatagcgt gaattatttt
      361 gtacttttag cttaggaatt ttgggaggcg ttgtattacc aaattttatt tgatttaata
      421 ttgcaaatat agttttgcac ttcaacaatg ttaccatagt aacgtttatt tttaagttag
      481 atgataattt attagccaat ttgataacta aaagactatt accacctagt ctaaaaaaat
      541 cattcgttat tccgacttta tcaagtggta gcttcagaac atccgcatat atcatacaaa
      601 tcttttgctc taattcattt cgtggagcta tatattcacc ttttgttaca aattccggat
      661 atggaagagc atttatatcc aatttaccat ttaccgtcaa tggtaatctt tcaattctta
      721 taaacatatc cggtaacata taatcaggta attttttaga catatatgct aatatttcag
      781 ttttatctaa ctctttatct gcgatatagt atgccatcaa atgcatattc tctgataatt
      841 ggttgtcgtt aatatctgaa ggttttttac ttaaaacaac acaatgctct atttgggggt
      901 aagagagcaa tatattttct atttcaccta attcaattct aaatccacgt actttaattt
      961 gaaaatcgtt cctaccaata aattcaatgt taccatccag taaataacgg gctaagtcac
     1021 cagttttgta aattctggca tttatgccaa gctgtctttc tttttctgtt tgaaatggat
     1081 tcgatatgaa gctctcatta gttaagtctg gaagattaag gtaaccaagt gctaacccca
     1141 ctcctccagc gtagatctct ccggtactac ctatgggtaa tggttttaag ttattgtcca
     1201 aaatatagca agtagtattt gaaattggtc ttccaatagg aaccatatct ataccattag
     1261 cactaaaatc ataatatagt atatcaacag tagcttctgt cggaccatac aaattatgta
     1321 ttctcaccgc aggtaattgc ctatgaagat ccttcgcata agacaatggt aggctctcac
     1381 cactgcaaaa aacatgacgt agcatattca aattaatgtt gctactgttt aacatggctt
     1441 ccaaagtttg cgtaaagatc ctaagcattg atggcacaaa atgcagtata gttatttcgt
     1501 tttgctcaac tagttttaca agatattcag ggcttttatg accatcaggt tttgcgaata
     1561 taattgtcgc accataccaa ttaccccaaa ataattccca gactgatacg tcaaatatat
     1621 atggtgtttt ttgtaacatt ttgtcatact taactaatgg atatttatca ttcatccatt
     1681 gaattctatt tacaacccct tgatgctgca gcatgacccc tttcggtact ccagtagttc
     1741 cacttgtata aattacatat gctaagtttt tacttgttat atttagtttt ggatcggata
     1801 ttggatattt ttttaaacct tgagcaaatt ctttatcatc tattatcaca tcatcacaaa
     1861 taatacttgg tgatctattg tttttagatt gccttacatt gctacgcaat gcttgcaacg
     1921 acttctgtac cacactcgcc gccttagtat cagtaattag aattttagcg cgtgtatctt
     1981 ttagaatgta atcaattcgt tcaattggaa aatcagggtc aattggcaca tacgctgccc
     2041 ctgactttaa tactcctaat attgcaatta acatgtattc gcttctattt aagcacaaag
     2101 caattaaatc atcacctttg atttgatagg tttctcttaa gtaatttgct aattgatttg
     2161 atctttcgtt taattctttg tatgttaatt ttatatcttc atacactatt gctatattat
     2221 ttgaagtttt agctacttgt tcctcaaata attggtgtat tgttttttct tgcgggtatt
     2281 ctttctccgt cttattccag tcataaacta ctttttgata atcctccttg gataataatg
     2341 gtaggttttt aactaatata tctgcccttt gcgcttcttt atgcccagca aaaagcatat
     2401 caatagtttt tataagcatt tttataaaat ccatatcttt tttgtaacac tttaccgata
     2461 tttcctttcg attaattacg aatactactt tatgattatc tatctcccct gaataattat
     2521 cagtgattgc caactcacta catagatttt gcttatatct gtagccaaag tctttaaaaa
     2581 tatgaatact attatcaatt gcctcattaa ttttctgagt catttcaata tagcgcaact
     2641 ctaaattatc ttggcagagc ttcaatatac ttatgttttc agtaattttt tttgtaagat
     2701 tacttctata attaatattt ttatggtaga tttttataaa agtctcatta gaattcagcc
     2761 tacttaaaat aattgataaa aacaaactta acatgtcaat agataattta atgtcaagct
     2821 taatgtcttg tctactgtta gacagcatag aatatgaaag taatcctgtt tgagcttgag
     2881 actctttaag taattcagat actctattgt gtatgttaaa ctcttctcgt ttaagttttc
     2941 tacaattaga aatatcagca acgcttaata cacactgctg gatttgagta atcttgaaac
     3001 ttttttgtac tttttcacca tacatatttc ttaaaataca agttgatgaa tcaataacat
     3061 caatattttc ttgttgtatt ttcttttcca agatatacga taaaccatta atttttacct
     3121 taacaatagt aactggattg acataaccat ctccaaaatt taggccatta agcaacttat
     3181 ttatacagaa tatgctatca gtagtattta aataagcata gttatctggt agataatctc
     3241 gtccaaaata agtcttttta gataaatctt gttttatccc aattaattta tcgtgttcaa
     3301 tatcagctat taattgttta aatcctatta atgcagcatc agtacacttg agatttagag
     3361 aaaatgctgt ttcaacatca ccgataggaa tttttgcttg gtaataaata tcgccttcat
     3421 cgatgccagc aattatttca tgccaagtaa tgccgtgaaa ttgctcattc cctaaaattg
     3481 cccatgtagt actattaacc ccagcatatt taggtaataa gctatcgtga taattaattg
     3541 cttttatcgg atcgatatgt gagattagtt tagtcgataa aatatacgga ttaatgatac
     3601 taaatacaaa acagcccttt gaaccacttg ttaattcaaa agattgttcc atatttaaac
     3661 accgtataga ccgctcttta caccaattac tcacagagtc atcctgtgtc aatacggcat
     3721 taatattcca gttattatgt agcaagtgct ctatgcagct aattgttaag ccagtctcac
     3781 caaagatgac tgcattttta ctaactaaca tcaagtatac ctaaataatg taaaaatcga
     3841 gctattgaaa tgaattaaga tcttgttata agcgtaattc cacaaattat aagagctgaa
     3901 ccaacggtct tatagaacat acctgtattt tctttaaaga atataaaacc taccattaaa
     3961 gataaaacaa tacacactcc aacatagata gggtatattt tcgaatattc atatttgcta
     4021 agtaaataaa cccagagaaa tgttgctagc aaataaaaca cccagccaac aataaaccat
     4081 aaatttgtga attgttttaa taataaacta tgcccatcag acaattgcag gacctgcctg
     4141 gaagaaattt tccagcatat ttgactaaaa acagttgaag atgttgctat aaaaaatata
     4201 atgataccat tcatatcaat tccaatctac aaaaaatttt attaaattct taatgtttta
     4261 cgcacaggca tatatgtgac acataagtac cgtgatcatt actttgtaat atatcttaat
     4321 attttacgcg taggcatata cgtaacacat aaagtcctgt gatcattact tgttatataa
     4381 ttttaatgtt atgagcagcc ttatatgtga cgcataaatt tatgaccatt gtttgttttg
     4441 taaaatttaa ttaattatta agaaagcttc gcaaattttg taggcatacg gaggcaaatt
     4501 gtatgcgcca tttaccaaac agtttaatat tagacttttt atttgaaata ttgatcgtgg
     4561 ctaatgatgt tccattgtaa tcaaaagtat aataagcaac agtctttgcc cagtatatat
     4621 tttaaactaa attgaactcg aaaagtaaaa tttatgaaaa attatctaaa taatgcttgc
     4681 gccactaggc aaaataaaag ccataaactt aaaatatcta aaaaactgta gctatttatt
     4741 ttttactgta acatattttt gtttcgggct tttaggtatc tccggtgtag ttagtgctag
     4801 tttgccttca gcaataagtg gcgataatat agtattacgg aaaaaagttt tatgctttaa
     4861 ccccagatat tgcattattt cttgtgctga acgtgggatt ttgcaaaact gtaaaataga
     4921 tgcttcattc ttgctagctt ggtcactagc ttggtcacta gcttggtcac tagcttggtc
     4981 actagcttgg tcactagctt gtctaaaccc tttatcaaat ggcagtgtaa ctctaataaa
     5041 gtttcgcgaa aaatggaaaa ctgttgtagg atacgattct aaaattcttg gcactcctga
     5101 ccccatatgt tcaaccaaat ccaggtcttt aaatacccgc ataagctctt tattctgagg
     5161 cacagaatat cccaggaaaa aatcttcttc attgaacccc ggaggcagcg ttccggctga
     5221 ggtaatttcc aggcgatccg caaatagttc aaattttggt ggtatctcat tgctataatc
     5281 gttatggata atagcgttaa taattgcttc acgtaacgcc gtagggtcta agagcttacg
     5341 ctccttcctc acagtatctg taattttagc aaaggtttta ttttcaacct taagtttctc
     5401 caatacagac ttggtagcct ttatcagaca gcacataccg tattcttcat tttcaattag
     5461 gtcaaccctg tttaacccag aatatttggc aacttttatt gataccccat tcatgtctga
     5521 tagcatataa gctgcataat tgtatttacc atcttcagtc aatagctcta aattctttgc
     5581 aaattgacca ttgagatcta gtttagcttc actatagtaa attcttaatt gctcaaaagt
     5641 taaatcctgg tagcgtgatc ttattgtacc aattgaatta cgaatccttc tggcaaataa
     5701 atcttcaatc attctctccg tcattggttc tgcagcactt ccaattcgaa tataacaccc
     5761 tcttgttgac atgcccattt tagataagta atatggtttt tctgagccgc tagctacaat
     5821 aaccttaacg acatatttac cttcttgcat ttcagtaaca acgtcaaata accccatagt
     5881 agatggactg atattatttt taatccgatc tttaatctta agctgtgtgt catcagggtt
     5941 aattactcca acaattgtac cagttttatc aataccaacg taaataatac cgccatcttt
     6001 ataattgaga aaagcaatta cctctttttc taacgaatcg cttaactcac gcttaaattc
     6061 aatatgatta ttttcctgca tttactatgt ccttactatc taatgctaaa ttatactact
     6121 tgtaatttca aagagttatt tgatttataa aactaaattc gatgtagctt cagctactcg
     6181 agtcatccaa tagaaaagga atttgattta acataattgc tttttcaacc aactgaccaa
     6241 tattaaaaac ctcaaatttt ggataaagct ttttattgat gattgcattt attgtactat
     6301 cagaaacagg cttgtcttct attatagtta taatttgcgc tatatccttt ggtgatttat
     6361 ttaatgatag ataataaagt acatctaact ctctttttgt aaggcgtatt tgtctgtcag
     6421 aactagatat gtttggttta ataccaattt gttcagttaa tgcttctatt ttataatttt
     6481 gaatatcacg ttgtatctta tcaataaatg tcaaaaattt tgcttgctct tttttctgaa
     6541 ctaaatatgc ttcattctca agcctgagat gttctgcttc tgtttctgct gctaactttt
     6601 caagaaatac ttgatttagt ttattttgcg cttccagctt tatattttca agccttaatc
     6661 gttcggcttc tttgtgtgca gtaatttcaa ttgaagtgcc aactacgcca attatcttac
     6721 catgcttgtt tcttaatggt gctctggtag ctgcaaagtg cttcactttt ccagtaacca
     6781 catcaatggt agtatcttcc gtttgtaaga ttttcccagt ttgaattact tcattaacaa
     6841 tttttaacaa cctatctgca ataaatttat ctttatacat ttcatacggg gtttgaccaa
     6901 taatatctgc tttatttaac gcccctacac ctttcatgga tagcgtatta cagcccatag
     6961 cacgcccctt cggatccagc caaaaaaacg cagctggaat taattcagca atagtttcca
     7021 aatattcaaa tatcgactcc ttctctccca tttattatct cctgaaaatg gtttgttatt
     7081 tcagcagcag tcatgcttaa tgtaatacat aatcaataat agactgttta attcggcttc
     7141 agatcgccac gctgcgctcg cgatgacaat tgggaagtta ttgattgtta tttgctacta
     7201 aatgaaattt ggataatttg cccgtataag atgtcatttt ttgaaatttg cgaaatcata
     7261 acataatttt tattttttat gtctgaaagc atggcttcag atttaaggga aatcaaatta
     7321 agggtggtgg cgtgattatc tatgatgtta tcggaaataa ctttagctga aaattcctta
     7381 tttttattaa atattttaaa aaaaatcgat attttgcttg ccgttgcagg ctttcccgtt
     7441 ttggagtcag gaatatctga aattcccata ctacctccag cgcataaatc attattaact
     7501 ctacatgtag atcctccaga gaatttatta gaaaattcct tggctaattt ctgactaaga
     7561 gtatcaagtt ctcctttttg aagtgcagta agggaaacaa tatttattga tgatgttagg
     7621 ttggctgttt tagataggtt atttatttct aaaaatttag caaattctgc tggcttcatc
     7681 tggtaattat atacagcata tttaacatcc attgctggcg ctaatgatgc tccttccata
     7741 tttttagagc ttggaattgc aacgacgctg ccaacattac cgataccact atccgcatat
     7801 acaatagcaa atagacaaat caaaaaaata aacatacatt ttttaaacat taaatttact
     7861 ccataatttt ataataaata cattactttc aggatcgcat atcacagtag cttctccatc
     7921 ctgattgata tgataaaaaa gatgcatatt aaaatacaaa aattgtaatt tgtacattct
     7981 ttcacataga taattaatta tgggttattg taccataatc tatactttga actccttgta
     8041 aaacagcctg tatatagctt tgtaccggat tttttccaga tgggtacaaa caaacaagtt
     8101 actccaatag agcatcttct gctaggtggc ggaaaattag ctgcacctat tacttgacag
     8161 ttatcattat ttatttcaag actttagaat aaagccacga actccaaagg tgaaataagg
     8221 ctggggggga aatcactaat ttgtaatgag tttggccaat cttgtctcag gaatcaattg
     8281 tagagaaact tagaaaaaat tgatatacca agttttggta caactttaaa tttggctgtt
     8341 gagaattagt tgctgtgcag agttaatcac ttgagttatc taataagaag ggtatttgat
     8401 ttaacataat tgcagtagcc atgcttaatg taattcatgg tcaataatag actgttttct
     8461 tcagcagtag atcgccacgc tgcgctcgcg atgaccagtg gtgctgcgct cgcgatgacc
     8521 agtggtgctg cgctcgcgat gaccagtggt gctgcgctcg cgatgacagc agcgctctcc
     8581 tagtctttag cgacgacatc tgcatccttc gaatttctcg caatgacgtg tatggttaaa
     8641 ttttgcgatt ctatcacata aattccaata gtcaactaaa tttacagccg acctgttaaa
     8701 attctaaaaa atatagtata atagtttctt tgatatagca aatttgatta ttcaacagca
     8761 acatatgaat tttgttatat ttatcttgct ttttaaaaat taagtgaatg aaattttact
     8821 aaggttattt tatgaataaa aagattttat ttttccctgg cggatggagc aaagctgagg
     8881 attcgttagc cccacaaatt gagtatttca aaaagttgcc aggttatgac gttatctgtc
     8941 ccaacattca ccaatttgat accgtaacta aaatgtcaga ctatgtacta cgaagctata
     9001 atgatgttca tgcagtagtt ggtttatcca tgggtgggtt tattgtacaa gacatcctaa
     9061 ctaaacaacc tacattttca tcaaaagcag taataatggg aagttttgcc catgcacaat
     9121 ttgacgaagc taaaatattc tttagacagt tgattaatca agttaaaagc aatggattgg
     9181 aagagatttg ccatttatat gctaaagata tgctatctga taactcattt ctaaataagt
     9241 cagatctagt tgccacagta atacaaattc cccagaattt aggtcaagag cagtgtatta
     9301 atcattctga agcttgtata acatgggatg gatgtcttga ttcacttaaa cagattaaaa
     9361 gcaaagtttt aattttagct gccgaattgg acaaagctac ccccatttca ggacaccgcc
     9421 aattgcatga attaattgct aactcttctt tgcaaatagt tccgaattct ggtcatttta
     9481 tgactttaga gcagccagag attgtaaata aatttatgca tgaatggttg ttgtaataga
     9541 acgtatctcc ctatcaattg cgaaccaaat ttaacctaaa atgtgaattt ttagctctta
     9601 ttgtaaattc actcagcaag taagtctaaa agtatgagaa aatatatact tataatcaac
     9661 caaacaggga ctcgctaaaa agagacccta ttgaattagt acagaacgga aaaaatcatg
     9721 tcacgttatc ttgacccaaa agcagatgtg gtctttaaaa aaatatttgg tgatcatcct
     9781 cacctgttga aaagcttttt aaatgcagta ttgccattat ctacggaggg gcaaattgtc
     9841 gaattagaat atttacctaa tgaacaagtt ccgcatatac ccgcctttaa gcggaccatt
     9901 gccgatgtta aatgcaaaga tatcaatggg cgcgtattta ttgtcgaaat gcaaattgac
     9961 tggactgatg gctttaagca gcgtttattg tttagtacca gccaagctgt cgtaaagcag
    10021 ttggagaagg gtgaatcata tcgtctttta caaccagttt atggattagg aatagttgcg
    10081 gatatttttg ataagacaaa tccagaatgg taccatcatt atcaattggt taaaaacggt
    10141 aattcaggat gtgatgttat tgaacatttg cagttggttt ttattgaact acctaaattc
    10201 ccagttcagt caccagaaga gaagaggctt agattattat ggctacgatt cttgcgtgaa
    10261 attgatgaga aaacaattaa tgtttcccag gaacttcttg atgtaccaga gatatcagaa
    10321 gctattgttc tggccgaagg agccgcctat actcccgggg aattgaatgc ctatgagact
    10381 tactgggatg ctgtcagaac agaaaagacc ttgatggagg gcagatatgc tgagggtgaa
    10441 gctaagggca gagctgaggg aattgaacaa cggactatag aaatggcaaa agctatgctt
    10501 ttacagggta tctcagtaga tatagctgca aatgtctctg gtttgccacg ggaaactctg
    10561 gccaaattaa ttgagaaaaa gtagaaaatt atactaataa ggtgtatgat gaatcaaaag
    10621 actggtgtaa aaaatcagaa aaagcaaact tttgaattag ctaaggaagt tctcgaattc
    10681 agtgatgaat gaatctgtaa aacattataa caatactggc ttgcattgta atagaagtga
    10741 aatgtctgtt tggctgggac gcttagctgt cggaaaaaaa gcatctgctc cgaaatgcca
    10801 caagtaatac tatcacccgg cttcattcaa gagttggaac ttattttata aatacagtta
    10861 caattattgt ggctatcttg acgatgatgc taaaacagtc accatcttct attttttgct
    10921 ggctaatttt gccagagttt cttgcgataa acccgagacg tttgcaacca catctaacga
    10981 tataccccgt aaaagcaggg cttctgccat ttccatttta ccttcaactt ttccttcaac
    11041 ttttcctttt gcttcacctt taatatattg tgtgtgaaat tcttcccgta catcaatcat
    11101 ctctattttg tagcgcatat aataagcttg ctcttccaaa ctcattttta gaaaatttaa
    11161 ccgttctgcc gccagcttta tatacttctc tttaaagtca tcttttatgg ct
//
