LOCUS       c00028_3300010..        5824 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300010401.a:Ga0134121_10016837.
ACCESSION   c00028_3300010..
VERSION     c00028_3300010..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 06:52:58
            Original ID  :: 3300010401.a:Ga0134121_10016837
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 5824
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..5823)
                     /NRPS_PKS="Domain: AMP-binding (87-488). E-value: 3.3e-105.
                     Score: 343.7. Matches aSDomain:
                     nrpspksdomains_ctg28_1_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (598-665). E-value: 6.3e-26. Score:
                     82.2. Matches aSDomain: nrpspksdomains_ctg28_1_PCP.1"
                     /NRPS_PKS="Domain: PKS_KS(Hybrid-KS) (696-1123). E-value:
                     2.4e-163. Score: 535.7. Matches aSDomain:
                     nrpspksdomains_ctg28_1_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (1220-1510). E-value: 2.3e-102.
                     Score: 334.1. Matches aSDomain:
                     nrpspksdomains_ctg28_1_PKS_AT.1"
                     /NRPS_PKS="Domain: PCP (1852-1920). E-value: 1.6e-25.
                     Score: 80.8. Matches aSDomain:
                     nrpspksdomains_ctg28_1_PCP.2"
                     /NRPS_PKS="type: PKS/NRPS-like protein"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     hyb_KS"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     390.7; E-value: 1.4e-118)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg28_1"
                     /sec_met_domain="AMP-binding (E-value: 4.5e-119, bitscore:
                     383.7, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 5e-20, bitscore:
                     58.1, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 4.6e-104, bitscore:
                     334.1, seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="hyb_KS (E-value: 7.6e-172, bitscore:
                     558.0, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LALSATQGDGWLHLAMEYSADLFDATTVQRLLARLATLAAAAVAF
                     PEQPVASLPLLTAGEHHQVLREWNDWTLGEALPAAEPLFHRLFEARVAATPERPALVWD
                     GTRVSYRELNRRANSLAHHLRAVGVGPESVVGLYMDRSPDLIAALLAILKAGGAYLPLD
                     PEAPADRTAFMLADGGVRVALADERRAVDLAGHGLQVICPPFGLSFAGDGPDANLAGGA
                     ASDHLAYVIYTSGSTGKPKGVMVSHRAACGTLLWRLSRFNLTPDDCVLQNIAFTFDPSV
                     WQIFGALLSGARLVLVPPGGQQDFAGLVRTMAHEGVTITDLAPPMLEAFLEQEGLEACH
                     LLRLLFAGGQALPAALATRFQERFPAADLQNIYGPTEVAIDAATWTCRPLPAGTIVPIG
                     RPVAGRRLLALDGDLSPVPVGVAGELYIGAAGLARGYLGQPALTAERFLPDPWAATPGE
                     RFYRTGDLVRQLADGLVEFLGRVDRQIKIRGFRVELGEVESAVASHPQVREAAVMVGPD
                     AQGQPRIIAYFAAADGSSLAAEDLRSFLRASLPSYMVPAALVKLPALPRTVSGKVDPQA
                     LPAPAEAAAGPSASGEAPRTGLERRIAEIWREVLGVEQVGIEDNFFDRGGHSLLLIRVH
                     SQLQKLLGREIPVVDLFNHPTIGALARHLGSLLPAANSDAVLAAARSRAREQMEWTGGQ
                     EGVAIVGLAGRFPGAADVEALWANLRSGQECIRSFSDEELLAAGVPTQVLTRPNYVKAR
                     GVLDGIDLFDAPFFDIPPREAEMMDPQHRLFLESAFHALESAGYDPARFPGAIGVYAGV
                     SANMYVLRNVLASAGALQAGGENQAMLGGDKDFLATRLSYKLNLRGPSFTVQTACSTSL
                     VATHLACRALLGRECDMALAGGVSATVPQVTGYNYQEGGISSPDGHCRAFDAQAQGTVG
                     GSGVGVVVLKRLSDALAAGDTIHAVIRGTAINNDGSQKVGYTAPGVDGQAAVIAAAQAL
                     AGVSPDEIRYVEAHGTGTPLGDPIEIAGLTRAFRAGTERTGFCAIGSVKTNLGHLDAAA
                     GIAGLIKTTLVLERGEIPPSLHFREPNPRIDFASSPFFVNAELRSWPADGGPRRAGVSS
                     FGIGGTNAHAVLESAPAPVPSGESRPSQLLVLSARSGEALEAATDNLANYLLAHPEVPL
                     ADAAYTLQVGRRLLAHRRVLVCRDAAGAAAALSARDPERLLTRTGDGGRRQVIFLFPGQ
                     GAQYAGMARELYEREPVYRAALDACAGILAPHLNGIDLLQTLHPEPDDAGADLRLQETG
                     LAQPALFAVEYALAQLWMQWGVLPEAMLGHSLGEYVAACLAGVFSLEDALALVAARGRL
                     MQSLPAGAMLAVPLSEEETVALLGDELSLAAVNAPSLCVISGPEVPIEAVRARLAQRGL
                     EARRLHTSHAFHSAALDSILEPFRELVSKVALHAPRLPYLSNLTGTWIEASQATDPGYW
                     VSHLRQPMRFATALGELLREPGRLLLEVGPGRTLSSLARRQAATAASLVESMRSPADTG
                     SDLGTLLTALGRLWLAGVEVSWDGFHAHEQRRRVPLPLYPFERRSYWIKPQSEPRPAGP
                     GAGTAAARRTEMAEWISTLVWKETVVVPRPLPADDERWLLLTDPCGLGAELAARLSAAG
                     RQVVTVSAGEGLAHEDGVRRLADLHASGLLPTRIVDLRSVTPEVSPTSAEAVEEPDFLS
                     LLSLLRLAATLKEATGDSILEMEATVVANGLCDLTGDERLSAEKAALLGLGRLVPVEYP
                     EVSCRVVDVRLPSPAGGPKWQELLAALFAELMMPPLEPLVVLRGNRRLAASANGPRLVE
                     PPPSLGLGLAGEGSREPEEVHSRPDLAIPYAAPRTETESALAGIWEEVLGIGPVGIHDD
                     FHQLGGHSLLALQVLSRVRQSLGSDLPLRAIFDAPTVARLAVRLLEGETVKADEGTLDD
                     LLAQLEGL"
     protocluster    1..5824
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[0:5823](-)"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(1..5823)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
     protocluster    1..5824
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[0:5823](-)"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      complement(1..5823)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="2"
     cand_cluster    1..5824
                     /SMILES="NC([*])C(=O)CC(=O)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /kind="chemical_hybrid"
                     /product="T1PKS"
                     /product="NRPS-like"
                     /protoclusters="2"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..5824
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T1PKS"
                     /product="NRPS-like"
                     /region_number="1"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX))"
                     /tool="antismash"
     aSDomain        complement(64..267)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg28_1_PCP.2"
                     /evalue="1.60E-25"
                     /label="ctg28_1_PCP.2"
                     /locus_tag="ctg28_1"
                     /protein_end="1920"
                     /protein_start="1852"
                     /score="80.8"
                     /tool="antismash"
                     /translation="ESALAGIWEEVLGIGPVGIHDDFHQLGGHSLLALQVLSRVRQSLG
                     SDLPLRAIFDAPTVARLAVRLLEG"
     aSModule        64..3735
                     /complete
                     /domains="nrpspksdomains_ctg28_1_PKS_KS.1"
                     /domains="nrpspksdomains_ctg28_1_PKS_AT.1"
                     /domains="nrpspksdomains_ctg28_1_PCP.2"
                     /locus_tags="ctg28_1"
                     /monomer_pairings="mal -> mal"
                     /tool="antismash"
                     /type="pks"
     aSDomain        complement(1294..2163)
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg28_1_PKS_AT.1"
                     /evalue="2.30E-102"
                     /label="ctg28_1_PKS_AT.1"
                     /locus_tag="ctg28_1"
                     /protein_end="1510"
                     /protein_start="1220"
                     /score="334.1"
                     /specificity="consensus: mal"
                     /specificity="Minowa: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /tool="antismash"
                     /translation="LFPGQGAQYAGMARELYEREPVYRAALDACAGILAPHLNGIDLLQ
                     TLHPEPDDAGADLRLQETGLAQPALFAVEYALAQLWMQWGVLPEAMLGHSLGEYVAACL
                     AGVFSLEDALALVAARGRLMQSLPAGAMLAVPLSEEETVALLGDELSLAAVNAPSLCVI
                     SGPEVPIEAVRARLAQRGLEARRLHTSHAFHSAALDSILEPFRELVSKVALHAPRLPYL
                     SNLTGTWIEASQATDPGYWVSHLRQPMRFATALGELLREPGRLLLEVGPGRTLSSLARR
                     QAATAASLVE"
     CDS_motif       complement(1411..1446)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg28_1_0012"
                     /evalue="6.80E-04"
                     /label="PKSI-AT-M_m8"
                     /locus_tag="ctg28_1"
                     /protein_end="1471"
                     /protein_start="1459"
                     /score="13.1"
                     /tool="antismash"
                     /translation="YWVSHLRQPMRFA"
     CDS_motif       complement(1669..1707)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg28_1_0011"
                     /evalue="2.90E-04"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="ctg28_1"
                     /protein_end="1385"
                     /protein_start="1372"
                     /score="14.0"
                     /tool="antismash"
                     /translation="AAVNAPSLCVISGP"
     CDS_motif       complement(1789..1911)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg28_1_0010"
                     /evalue="4.30E-27"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="ctg28_1"
                     /protein_end="1345"
                     /protein_start="1304"
                     /score="86.6"
                     /tool="antismash"
                     /translation="GVLPEAMLGHSLGEYVAACLAGVFSLEDALALVAARGRLMQS"
     CDS_motif       complement(1918..1974)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg28_1_0009"
                     /evalue="6.30E-05"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="ctg28_1"
                     /protein_end="1302"
                     /protein_start="1283"
                     /score="16.0"
                     /tool="antismash"
                     /translation="GLAQPALFAVEYALAQLWMQ"
     CDS_motif       complement(2113..2169)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg28_1_0008"
                     /evalue="1.20E-07"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="ctg28_1"
                     /protein_end="1237"
                     /protein_start="1218"
                     /score="23.7"
                     /tool="antismash"
                     /translation="IFLFPGQGAQYAGMARELYE"
     aSDomain        complement(2455..3735)
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg28_1_PKS_KS.1"
                     /evalue="2.40E-163"
                     /label="ctg28_1_PKS_KS.1"
                     /locus_tag="ctg28_1"
                     /protein_end="1123"
                     /protein_start="696"
                     /score="535.7"
                     /tool="antismash"
                     /translation="VAIVGLAGRFPGAADVEALWANLRSGQECIRSFSDEELLAAGVPT
                     QVLTRPNYVKARGVLDGIDLFDAPFFDIPPREAEMMDPQHRLFLESAFHALESAGYDPA
                     RFPGAIGVYAGVSANMYVLRNVLASAGALQAGGENQAMLGGDKDFLATRLSYKLNLRGP
                     SFTVQTACSTSLVATHLACRALLGRECDMALAGGVSATVPQVTGYNYQEGGISSPDGHC
                     RAFDAQAQGTVGGSGVGVVVLKRLSDALAAGDTIHAVIRGTAINNDGSQKVGYTAPGVD
                     GQAAVIAAAQALAGVSPDEIRYVEAHGTGTPLGDPIEIAGLTRAFRAGTERTGFCAIGS
                     VKTNLGHLDAAAGIAGLIKTTLVLERGEIPPSLHFREPNPRIDFASSPFFVNAELRSWP
                     ADGGPRRAGVSSFGIGGTNAHAVLESAPA"
     CDS_motif       complement(2677..2721)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg28_1_0007"
                     /evalue="2.20E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="ctg28_1"
                     /protein_end="1049"
                     /protein_start="1034"
                     /score="10.7"
                     /tool="antismash"
                     /translation="GSVKTNLGHLDAAAGI"
     CDS_motif       complement(2782..2829)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg28_1_0006"
                     /evalue="1.60E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="ctg28_1"
                     /protein_end="1014"
                     /protein_start="998"
                     /score="13.6"
                     /tool="antismash"
                     /translation="YVEAHGTGTPLGDPIEI"
     CDS_motif       complement(3205..3252)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg28_1_0005"
                     /evalue="4.00E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="ctg28_1"
                     /protein_end="873"
                     /protein_start="857"
                     /score="18.8"
                     /tool="antismash"
                     /translation="GPSFTVQTACSTSLVAT"
     misc_feature    complement(3679..3681)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     aSDomain        complement(3829..4029)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg28_1_PCP.1"
                     /evalue="6.30E-26"
                     /label="ctg28_1_PCP.1"
                     /locus_tag="ctg28_1"
                     /protein_end="665"
                     /protein_start="598"
                     /score="82.2"
                     /tool="antismash"
                     /translation="ERRIAEIWREVLGVEQVGIEDNFFDRGGHSLLLIRVHSQLQKLLG
                     REIPVVDLFNHPTIGALARHLGS"
     aSModule        3829..5562
                     /complete
                     /domains="nrpspksdomains_ctg28_1_AMP-binding.1"
                     /domains="nrpspksdomains_ctg28_1_PCP.1"
                     /locus_tags="ctg28_1"
                     /monomer_pairings="X -> X"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(4330..4395)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg28_1_0004"
                     /evalue="3.10E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg28_1"
                     /protein_end="498"
                     /protein_start="476"
                     /score="35.3"
                     /tool="antismash"
                     /translation="FLGRVDRQIKIRGFRVELGEVES"
     aSDomain        complement(4360..5562)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg28_1_AMP-binding.1"
                     /evalue="3.30E-105"
                     /label="ctg28_1_AMP-binding.1"
                     /locus_tag="ctg28_1"
                     /protein_end="488"
                     /protein_start="87"
                     /score="343.7"
                     /specificity="consensus: X"
                     /tool="antismash"
                     /translation="FEARVAATPERPALVWDGTRVSYRELNRRANSLAHHLRAVGVGPE
                     SVVGLYMDRSPDLIAALLAILKAGGAYLPLDPEAPADRTAFMLADGGVRVALADERRAV
                     DLAGHGLQVICPPFGLSFAGDGPDANLAGGAASDHLAYVIYTSGSTGKPKGVMVSHRAA
                     CGTLLWRLSRFNLTPDDCVLQNIAFTFDPSVWQIFGALLSGARLVLVPPGGQQDFAGLV
                     RTMAHEGVTITDLAPPMLEAFLEQEGLEACHLLRLLFAGGQALPAALATRFQERFPAAD
                     LQNIYGPTEVAIDAATWTCRPLPAGTIVPIGRPVAGRRLLALDGDLSPVPVGVAGELYI
                     GAAGLARGYLGQPALTAERFLPDPWAATPGERFYRTGDLVRQLADGLVEFLGRVDRQIK
                     IRG"
     CDS_motif       complement(4483..4572)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg28_1_0003"
                     /evalue="7.80E-16"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg28_1"
                     /protein_end="447"
                     /protein_start="417"
                     /score="50.1"
                     /tool="antismash"
                     /translation="PVGVAGELYIGAAGLARGYLGQPALTAERFL"
     CDS_motif       complement(5083..5142)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg28_1_0002"
                     /evalue="2.10E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg28_1"
                     /protein_end="247"
                     /protein_start="227"
                     /score="35.5"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGKPKGVMVSHR"
     CDS_motif       complement(5335..5376)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg28_1_0001"
                     /evalue="1.20E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg28_1"
                     /protein_end="163"
                     /protein_start="149"
                     /score="18.4"
                     /tool="antismash"
                     /translation="LAILKAGGAYLPLDP"
ORIGIN
        1 aaggccttcg agctgggcca gcaggtcgtc gagcgtgccc tcatcggcct tgaccgtctc
       61 gccttcgagc aggcgcaccg cgagccgcgc cacggtcgga gcgtcgaaaa tcgcccgcag
      121 gggaaggtcg ctgcccagcg actggcgcac tcgcgacagc acctggagag ccagcagcga
      181 gtggcctccg agctggtgaa aatcgtcatg gatgccgacc ggtccgatcc ccagcacctc
      241 ttcccagatg cccgccaggg cgctttcagt ctcggttcgc ggtgccgcat aagggatcgc
      301 gaggtcaggg cgggaatgga cctcctcagg ttcgcgagac ccctcccctg ccaggccgag
      361 ccccagcgac ggcggaggtt cgacgagccg cggcccgttc gcgctggccg cgaggcgccg
      421 gtttccccgc agcacgacga gaggctcgag tggcggcatc atcagctcgg cgaagagggc
      481 cgcgagcaac tcctgccatt tcgggccgcc agctggcgac ggcagtcgga cgtccaccac
      541 ccggcagctc acctccggat actccacggg aaccagccgc cccagcccca gcagggccgc
      601 cttctcggcg ctcaggcgct cgtcaccggt cagatcgcag agaccgttgg cgaccaccgt
      661 cgcctccatc tccaggatgg aatcgccggt cgcttccttc aaggttgcgg ccagccggag
      721 caggctcaag aggctcagaa agtccggttc ctccaccgcc tccgcgctcg tcggtgaaac
      781 ctccggcgtg acgctccgca gatccacgat gcgggtgggc agcaagccgc tggcatgaag
      841 atcggcgagc cggcgaacgc catcttcgtg cgccaagccc tctccggcgc tcaccgtgac
      901 gacctgccgc cccgcagccg acagcctggc cgccagctcg gctcccagac cgcaaggatc
      961 ggtcagtagc agccaacgct cgtcgtcggc aggaagcggc cggggtacca ccacggtctc
     1021 cttccatacc agggtcgaaa tccactcggc catctccgtc cgccgggcgg ccgcggtccc
     1081 ggcaccgggg ccggcaggcc ggggctcgct ctgcggcttg atccaatagc tccggcgctc
     1141 gaacgggtag agcggcagag gcacgcgccg ccgttgttca tgggcgtgaa atccatccca
     1201 ggagacctcc acgcccgcca accacagccg cccgagggcg gtgagcagcg tgccgagatc
     1261 cgatcccgta tccgccggcg agcgcatcga ctcgacgagg cttgcggcgg tggccgcctg
     1321 gcgtctggcg agggacgaca gcgtgcgccc ggggcccact tccagcagca atcggcccgg
     1381 ctcgcgcagc agctcgccaa gagccgtggc gaagcgcata ggctggcgga ggtggctcac
     1441 ccagtagccc gggtcggtcg cttgggatgc ctcgatccag gtgccggtca ggttcgagag
     1501 gtacggcagg cggggtgcgt gcaaggccac cttcgacacc agctcacgga acggctccag
     1561 gatggaatcg agcgccgcgg aatggaaggc gtgggaggtg tgcaggcgcc gcgcctccag
     1621 ccctcgctgg gcgagccggg cgcgcaccgc ctcgatcggg acctcgggac ccgagatgac
     1681 gcacagcgac ggagcattga ccgccgccag agagagctcg tcgcccagca gcgcgacggt
     1741 ctcctcttcc gacaggggca cggccagcat ggcgcccgcc ggcagcgact gcatcaaccg
     1801 gccgcgcgcc gccaccaggg ccagcgcatc ctccagggag aagacgcccg ccaggcaggc
     1861 cgccacatat tcgccgaggc tgtggcccag catcgcttcg gggagcaccc cccactgcat
     1921 ccacaactgc gccagcgcgt attcgacggc gaagagcgcc ggctgggcga ggccagtctc
     1981 ctggagacgg aggtccgcgc ccgcatcgtc cggctcggga tggagggtct ggagcaagtc
     2041 gatgccattc aggtggggag cgaggatccc ggcgcaggcg tcgagagcgg cgcgatacac
     2101 cggctcccgt tcatacagct cgcgggccat tccagcgtac tgagcgccct ggccgggaaa
     2161 gaggaagatg acctggcgcc ggccgccgtc gcccgtccgg gtgagcagcc gctcgggatc
     2221 gcgcgctgag agcgccgccg ccgcccccgc ggcatcgcgg cacaccagca cccggcggtg
     2281 ggccaggagc cggcgaccca cctgcaacgt gtaggcggcg tccgccagcg gcacttccgg
     2341 gtgtgccagc agataattcg ccaggttgtc cgtcgccgcc tccaaggctt cgcccgagcg
     2401 cgccgagagc accagcagct gggagggccg cgactccccc gaggggaccg gggctggcgc
     2461 actctcgagc acggcgtgcg cgttggtgcc gccgatgccg aaagagctca ccccggcccg
     2521 gcgcggtccg ccgtccgccg gccacgaacg cagctcggcg ttgacgaaga aggggctcga
     2581 cgcgaagtcg atgcgagggt tgggctcgcg gaagtggagg ctgggaggaa tctccccgcg
     2641 ctccagcacc agggtggtct tgatcagccc ggcgatgccg gccgccgcgt ccagatggcc
     2701 gagattggtc ttcaccgagc cgatggcgca gaagccggtg cgctcggtgc cggcacggaa
     2761 agcgcgggtg aggcccgcga tctcgatggg atcgcccagg ggtgtgccgg tgccgtgcgc
     2821 ctcgacatac ctgatctcgt ccggcgagac gccggcaagc gcctgggccg ccgcaatcac
     2881 cgcggcctgg ccgtcgacgc cgggggccgt gtagcccacc ttctgcgagc cgtcgttgtt
     2941 gatcgccgtg ccgcggatga cggcgtggat ggtgtccccc gccgccagcg cgtcgctcag
     3001 ccgcttgagc accaccaccc ccacgccgct gccgccgacg gtgccctgcg cctgggcgtc
     3061 gaaggcccgg cagtgcccgt ccggcgagct gatgcccccc tcctggtagt tgtagcccgt
     3121 cacctgcggc acggtggccg agacgccgcc ggcgagcgcc atgtcgcact cgcggccgag
     3181 cagcgcccgg caggcgagat gggtggcgac gagcgaggtc gagcaggcgg tctgcaccgt
     3241 gaagctggga cctcgcaggt tcagcttgta cgacaggcgg gtggcgagaa agtccttgtc
     3301 gccccccagc atggcctggt tctcgccgcc ggcctgaagg gctccggcgc tggccaggac
     3361 gttcctcagc acgtacatgt tggcgctcac tccggcgtag acgccgatgg cgccgggaaa
     3421 ccgggccggg tcgtagcccg cgctctccag ggcgtggaag gcgctctcca ggaacaggcg
     3481 gtgctgcgga tccatcatct cggcttcgcg cggcgggatg tcgaaaaacg gcgcgtcgaa
     3541 caggtcgatg ccgtcgagca caccgcgggc cttgacgtaa ttcgggcgcg tcagaacctg
     3601 cgtcggaacg ccggccgcca ggagctcttc gtcgctgaag gagcgaatgc attcctgtcc
     3661 cgagcgcagg ttggcccata acgcctcgac gtcggcggcg cccgggaagc ggcccgcgag
     3721 cccgacgatg gcgactccct cctggccccc cgtccattcc atctgctccc gggcgcggct
     3781 ccgcgccgcc gccagcacgg cgtcgctgtt tgccgccgga agcagactgc ccaggtggcg
     3841 ggccagggcg ccgatggtcg gatggttgaa cagatcgacc accggaatct cgcggccgag
     3901 aagcttctgc agctgcgagt ggacgcggat gagcagcagc gagtggccgc cgcggtcgaa
     3961 gaaattgtcc tcgatgccca cctgctcgac gccgagcacc tcgcgccaga tctcggcaat
     4021 tctccgttcg agacccgttc gcggcgcctc gccggacgct gacgggccgg ccgctgcctc
     4081 cgccggcgcg ggcagcgctt ggggatcgac cttgccgctc accgtccgcg gcagcgccgg
     4141 cagtttcacc aaggccgccg gcaccatgta ggacggcagg ctggcgcgca agaagctgcg
     4201 caggtcttcg gcggccagcg agctgccgtc ggcagccgcg aagtaggcga tgatgcgtgg
     4261 ttggccctga gcatccggcc ccaccatgac ggccgcctcg cgcacctggg ggtggctggc
     4321 gacggccgat tcgacctccc ccagctccac ccggaaacca cggatcttga tctggcggtc
     4381 gacccggccc aagaactcca ccaggccgtc ggcgagctgg cgcaccaggt ctcccgtgcg
     4441 atagaagcgc tcccccggcg tcgccgccca gggatccggc aggaaacgct cggcggtcag
     4501 cgccggctgg ccaagatagc cgcgggcgag ccctgcggcg ccaatataca actcgccggc
     4561 gactccgacc ggcaccggcg acaggtcacc gtcgagggcc agcaggcggc gtcccgcaac
     4621 cggcctgccg atgggcacga tagttcccgc cggcagcggc ctgcaggtcc aggttgcagc
     4681 gtcgatcgca acctcggtgg ggccgtagat gttctgcagg tccgccgccg ggaagcgctc
     4741 ctggaagcgc gttgcgagag cggccggcag cgcctggccg ccggcgaaga gcagcctcag
     4801 caagtggcac gcctccaatc cttcctgctc caggaaagcc tcaagcatgg gcggcgcgag
     4861 atcggtgatg gtcacccctt cgtgggccat ggtgcgcacc agaccggcaa aatcctgctg
     4921 gccgcccggg ggaaccagca ccaaccgcgc gccggaaagc agggcgccga agatctgcca
     4981 gaccgaaggg tcaaaggtga aagcgatgtt ctgcaggacg cagtcgtccg gcgtgagatt
     5041 gaagcgagag agacgccaga gcagcgtgcc gcatgccgcg cggtgcgaga ccattacgcc
     5101 cttgggtttg ccagttgagc ccgaggtgta gatcacatag gccaaatgat cggacgctgc
     5161 gccgcccgcg aggttggcgt cgggcccgtc gccggcgaag gacagaccga acggtggaca
     5221 gatcacctgc aagccatgcc cggcaaggtc gaccgcccgg cgctcatcgg ccagcgccac
     5281 ccgtacgccg ccatcggcca gcatgaaggc cgtgcggtcc gccggcgcct ccgggtcaag
     5341 gggaagatag gcgccgcctg ccttgagtat ggcgaggagg gccgcgatca gatcgggcga
     5401 acggtccatg tacaggccga ccacagattc cggcccgacg ccgacggcgc ggaggtggtg
     5461 ggccaggctg ttggcccgcc ggttgagctc acggtagctc acccgcgtgc cgtcccacac
     5521 caaagccggc cgttccggcg tggcggccac ccgagcttcg aatagacgat gaaagagcgg
     5581 ttcagcggcg ggcagcgcct cgcccagcgt ccagtcgttc cactcccgca gtacttggtg
     5641 atgctcgccg gccgtcagca gcggcagcga agcgacaggc tgctcgggaa aggccacggc
     5701 tgccgcggcc agggttgcga gccgggccag gagccgctgc acggtcgtgg cgtcgaacag
     5761 gtcggcgctg tactccatgg ccaggtgcag ccacccgtcg ccctgggtgg cggagagggc
     5821 cagg
//
