LOCUS       c00103_3300010..       11679 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300010401.a:Ga0134121_10004316.
ACCESSION   c00103_3300010..
VERSION     c00103_3300010..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 06:52:58
            Original ID  :: 3300010401.a:Ga0134121_10004316
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 11679
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..11679
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3971:5033](+)"
                     /cutoff="20000"
                     /detection_rule="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /neighbourhood="20000"
                     /product="T3PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3972..5033
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /neighbourhood="20000"
                     /product="T3PKS"
                     /protocluster_number="1"
     cand_cluster    1..11679
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /kind="single"
                     /product="T3PKS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..11679
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T3PKS"
                     /region_number="1"
                     /rules="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /tool="antismash"
     CDS             complement(3..308)
                     /locus_tag="ctg103_1"
                     /transl_table=11
                     /translation="MKYFGQPDFQHGEVPAVGVLLANLGTPDAPDSPALRRYLREFLLD
                     PRVIEMPRVLWWVILHLFVLTTRPPKSAALYKKVWTAEGSPLLVITKRQAAALQEVL"
     CDS             complement(329..1534)
                     /locus_tag="ctg103_2"
                     /transl_table=11
                     /translation="MTDAKPRIAILGGGPTGLEAALAAADGGFPFTVYESATSIAGNVR
                     AWGHVRLFTPWEMNVSPRMRRHLGAAGAETPDGSACPTGRELAEQLFEPLARLPKIAPH
                     LRLGTRVLGIGREGLLKHEEIATAERGRRPFRLLLADDAGREWTESADLVIDATGTWGN
                     PNTLGDAGIPAPGERNFGGEIRRDIPDFAREAADWAGKTVLLAGAGHSAQTAARDLSRL
                     AQEAPDTEVIWVLRNPEPSWGTHPGDPLPERAGLAAMAAALAAGVSPAVEVRRGAAVEE
                     ISKPNGKFHVVLRNGSGPEAVKVDRILSLTGAVGDHGLYRQLQVHECYATCGPIKLSGA
                     LLGAGSSDCLAQTSHGADTLTNPEPGFFILGSKSYGRNNTFLMRIGWEQVGEVFGLLDS
                     RP"
     misc_feature    complement(1076..1078)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     CDS             complement(1566..2528)
                     /locus_tag="ctg103_3"
                     /transl_table=11
                     /translation="MPEKLTAHRGLATWGERLVPLATFRQAAAEAGLTLTPEEREAALR
                     DYGAPVFDPTPIEGPYSRIAVFGGVYSNHYALAEVLEEAARRGAEAIYCLGDLGAFGPN
                     PEKVWPLLVQGKVLAIQGNYEESLASGREDCNCGYTDPRDNHFAEISYRYTAQNSSPEF
                     KAWMGTLPRRRRVRVGNRELLLVHGSPRRVNEFLFQSTSPVPFLEVLLDQNRCDGILCT
                     HTGLHWHRRLPSGREVVNAGVIGRPANDGNIHVWFAMLEAREEGLGVELLPLRYDHAGL
                     AAEMRRERLPEEFVETVLTGWWTTCLEILPARERAASRF"
     misc_feature    complement(2397..2399)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     CDS             complement(2539..3399)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg103_4"
                     /sec_met_domain="PF04055 (E-value: 2.2e-21, bitscore: 66.8,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 1.4e-09, bitscore: 28.3,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTPEVTLKSLDTLWFQVGGTVCNLACTHCFVSCSPTNHTHEFLT
                     LAEVRRYLDEASRLGVREYYFTGGEPFLNPEMEAILEATLAVGPATVLTNGLLLDPARC
                     ASLKKLAAAAEYSLDVRVSVDGYDAESNDAIRGAGTFERILVGARNLHEAGLNPVITVT
                     EVCREAITDSGKEKFFALLRSMGIERPRLKVLPVFQIGAEAERGGAYESWQHLKEEDVP
                     EGGWDHLQCSSCRMVTDQGVWVCPILVNEPSAKMGETLADTLGAFPLGHSACWTCHVYG
                     VSCRT"
     CDS             3632..3922
                     /locus_tag="ctg103_5"
                     /transl_table=11
                     /translation="LLPGWVMLATWVLEAIALSALYLLIQGRGGARWLNGLLTGWIAWV
                     FRGPLLVVTVVGMAGLPHGPWWAMAFSWLVLYTFCGLILGGAAAAAGLQQP"
     CDS             3972..5033
                     /gene_functions="biosynthetic (rule-based-clusters) T3PKS:
                     Chal_sti_synt_N"
                     /gene_functions="biosynthetic (rule-based-clusters) T3PKS:
                     Chal_sti_synt_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:chalcone and stilbene synthase domain protein
                     (Score: 406.6; E-value: 1.1e-123)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg103_6"
                     /sec_met_domain="Chal_sti_synt_N (E-value: 5.7e-26,
                     bitscore: 81.2, seeds: 21, tool: rule-based-clusters)"
                     /sec_met_domain="Chal_sti_synt_C (E-value: 7.3e-21,
                     bitscore: 64.8, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LRIAAVGRSLPPHYYDQETLLAALRRRWSDRYFNLERLERLHKNV
                     LVGGRHLALPIEEYDTLTTWGKANDAWIRVAQEVGARAVLDGLDKAGLSTDDVDALIFV
                     TVTGVATPSIDARLMNLLGLRSRVKRMPIFGLGCVAGAAGIARAADYVRAFPDQVAVLL
                     SVELCSLTLQPEDLSIPNLIASGLFGDGAAAAVVTGADRPQTGQSIGTRIVDSRSVFYP
                     DSERVMGWDISETGFKIVLSADVPLVARDKLRPDVDSFLAEHGLKVSDIASWVCHPGGP
                     KVLEAMQEALDLPPGALDVTWRSLQEVGNLSSTSVLMVLAETLENHRPPPDSYGVLLAM
                     GPGFCSELVLLQW"
     misc_feature    4041..4043
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     CDS             5030..5620
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1150:isoprenylcysteine carboxyl methyltransferase
                     (Score: 213.1; E-value: 3.9e-65)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg103_7"
                     /transl_table=11
                     /translation="VSDTRILYTLLVALVALGRLFELRIASRNRQRLLARGGVEVAPGH
                     YPWMVALHTALLISCPVEVWLLRRPFVPFLAASMLVLLVLAGALRWWVIQTLDGRWTTR
                     IVVLPGVPPVVGGPYRFLRHPNYLAVILEIFSLPMIHSAWLTAIVFSLADALLLRVRIR
                     AEEAGLSRVSGYEAAFADRPRLIPGGVPGGGGD"
     CDS             5629..5859
                     /NRPS_PKS="Domain: PP-binding (6-69). E-value: 9.6e-08.
                     Score: 24.3. Matches aSDomain:
                     nrpspksdomains_ctg103_8_PP-binding.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg103_8"
                     /sec_met_domain="PP-binding (E-value: 2.6e-08, bitscore:
                     24.3, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VILAGIAEVARAHLGWDGVVTPDLRLIEDLRLDSIRLLTLAAEVE
                     NRFRVLLDEGDEAGIETVGDLVAVVRGKLDA"
     aSDomain        5647..5835
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg103_8_PP-binding.1"
                     /evalue="9.60E-08"
                     /label="ctg103_8_PP-binding.1"
                     /locus_tag="ctg103_8"
                     /protein_end="69"
                     /protein_start="6"
                     /score="24.3"
                     /tool="antismash"
                     /translation="AEVARAHLGWDGVVTPDLRLIEDLRLDSIRLLTLAAEVENRFRVL
                     LDEGDEAGIETVGDLVAVV"
     aSModule        5647..5835
                     /domains="nrpspksdomains_ctg103_8_PP-binding.1"
                     /incomplete
                     /locus_tags="ctg103_8"
                     /tool="antismash"
                     /type="unknown"
     CDS             5852..7561
                     /NRPS_PKS="Domain: CAL_domain (36-467). E-value: 5e-116.
                     Score: 379.7. Matches aSDomain:
                     nrpspksdomains_ctg103_9_CAL_domain.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     371.3; E-value: 1e-112)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg103_9"
                     /sec_met_domain="AMP-binding (E-value: 2.8e-92, bitscore:
                     299.2, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPERPEGILDWLEQAGRRPEGGLRFVDRTETATWFGWAEIRERAR
                     AACGGMQALGIERGARVALIFPTGIDFFVAFFGALLAGAVPVPLYPPARLGRREEYVRR
                     TAQLLERSGARLILSESRLCRILGDALQETHLALGCRTLEDLPVESPRTILAAPSDLAL
                     VQFSSGTTGDPKPVALSHRAVAAQAEILAGFWPDSPEQRQSCVSWLPLYHDMGLIGCVF
                     PALARDATLTLFAPELFVACPALWLRTLSRYRATISPAPNFAYNLCLNRVSDKDMEGVD
                     LSGWQTALNGAESISPGVLQAFCERFAAWGFRPEAMTPVYGLSEAALAVTFSDLARPYR
                     VTHFDREKLAREGRARASVNGREIVSVGRPVPGFRLRIVGPEGCDLPAGDVGQVWIQGP
                     SLMEGYLGDPEATANVLRDGWLDTGDLGFQYAGELYLAGRAKDAVILRGRNHAPEEIER
                     AVEEVPGLRTSSAVAVSWLPEDAPGEELALFVEASRQAAPEELAALPDACREAVLGATG
                     LAVDRLEVLAPGTLPRTSSGKLRRGETLRLYLAGELAGLESAASLRLSGVLA"
     aSDomain        5960..7252
                     /aSDomain="CAL_domain"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg103_9_CAL_domain.1"
                     /evalue="5.00E-116"
                     /label="ctg103_9_CAL_domain.1"
                     /locus_tag="ctg103_9"
                     /protein_end="467"
                     /protein_start="36"
                     /score="379.7"
                     /specificity="Minowa: NH2"
                     /tool="antismash"
                     /translation="WAEIRERARAACGGMQALGIERGARVALIFPTGIDFFVAFFGALL
                     AGAVPVPLYPPARLGRREEYVRRTAQLLERSGARLILSESRLCRILGDALQETHLALGC
                     RTLEDLPVESPRTILAAPSDLALVQFSSGTTGDPKPVALSHRAVAAQAEILAGFWPDSP
                     EQRQSCVSWLPLYHDMGLIGCVFPALARDATLTLFAPELFVACPALWLRTLSRYRATIS
                     PAPNFAYNLCLNRVSDKDMEGVDLSGWQTALNGAESISPGVLQAFCERFAAWGFRPEAM
                     TPVYGLSEAALAVTFSDLARPYRVTHFDREKLAREGRARASVNGREIVSVGRPVPGFRL
                     RIVGPEGCDLPAGDVGQVWIQGPSLMEGYLGDPEATANVLRDGWLDTGDLGFQYAGELY
                     LAGRAKDAVILRGRNHAPEEIERAVEEVPGLRT"
     aSModule        5960..7252
                     /domains="nrpspksdomains_ctg103_9_CAL_domain.1"
                     /incomplete
                     /locus_tags="ctg103_9"
                     /starter_module
                     /tool="antismash"
                     /type="unknown"
     CDS_motif       6335..6394
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg103_9_0001"
                     /evalue="2.50E-05"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg103_9"
                     /protein_end="181"
                     /protein_start="161"
                     /score="17.0"
                     /tool="antismash"
                     /translation="ALVQFSSGTTGDPKPVALSHR"
     CDS_motif       7010..7090
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg103_9_0002"
                     /evalue="5.50E-10"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg103_9"
                     /protein_end="413"
                     /protein_start="386"
                     /score="31.5"
                     /tool="antismash"
                     /translation="PAGDVGQVWIQGPSLMEGYLGDPEATAN"
     CDS_motif       7160..7222
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg103_9_0003"
                     /evalue="6.10E-05"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg103_9"
                     /protein_end="457"
                     /protein_start="436"
                     /score="15.7"
                     /tool="antismash"
                     /translation="AGRAKDAVILRGRNHAPEEIER"
     CDS             7558..8649
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1161:oxidoreductase (Score: 318.7; E-value: 7.8e-97)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg103_10"
                     /transl_table=11
                     /translation="MTDLLVIGGGPAGLATAIRARLAGLTVTVLDRARPPIDKACGEGL
                     MPDAVKRLREIGIEPRGFPFRGIRYIDGNLMAEGHFPGSGGLGVRRTELHAALVRRAEQ
                     VGVDLRWGVKAEGLTDEGVRTDQGILAARWIVGADGLRSQVRRWARLDGKLSPLRRFGI
                     RRHFAVTPWSDCVEVHWGPESEAYVTPVSSDEVGIAVLWSGQKAGFDGLLESFPTLKEK
                     VENAPVASRDRGMGPLRQQVRAVINGRVALVGDAAGYLDAITGEGLAVTLQESAALVEA
                     LTRGDLSRYSAAHRRINRLPNFMTSMVLGLERRPRLRRRVLRALAAEPSLFARLLGIHA
                     RTLPPRDFGFEGALRLAWRLVAA"
     CDS             8665..9261
                     /locus_tag="ctg103_11"
                     /transl_table=11
                     /translation="MHCRRIALSIVSALAFASVLSAEQVTFELDPAATTIEFTFGATLH
                     TVDGTIRAKEGTIHVDSETGAATGRIVIDATSAKTGNARRDRKMHEKILESERYPEMIF
                     EIERLSGKLNPIGQSEIELHGNLEMHGTRLPIGLPATVMTTDGKTVTGTGNLILSYLKW
                     GLADPSVFLLRVEKEVHVTVKAAGSIRTEGAPPTQ"
     CDS             9556..11118
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="other (smcogs) SMCOG1277:Radical SAM
                     domain protein (Score: 89.5; E-value: 3.2e-27)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg103_12"
                     /sec_met_domain="PF04055 (E-value: 3.2e-23, bitscore: 72.8,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKPAHDWSPFLSDERPVERFSPHGRYRLALAYANSYHIGMSSLG
                     FQRVYELIHRRPDWSCERLFTDGVGMPVSLETRRSMNDFGCIAFSVSFEEDYVNLLQML
                     DRARIPVRRRDRGPWDPVIVLGGSCAAINPLPMSEFVDVFTLGAAENVLPHLLDALEGE
                     EGREAVIERLAALDGFYVPAFHHPEDDGDELPKLNKLELTEEQMKQTGNLPTTCIVTPR
                     TEFSEKFLIEMSRGCPEKCRYCWATFGMGRFRWHPTDEILAALERAKPVTNQLGFVATA
                     VGDHPDIEPILREANKLGFRTSVSSIRIPAVTEGVLEALHASGDRSITLAPETGTDELR
                     VKMGKPIKNEFLLEKIRLIFRHGFTQLKLYFLIGLPGETMEDIQGILDLAARARAVMLE
                     ELPKKGMIGNIHLGTNVLVPKPYTPWQREPMDDERSLKEKIAILKKGVSRMPNISLGSI
                     SVRQAIWQTYISKAGSDAADAIEAAARGESISSVLHRFAPQIHPEVYGRLEGDLRWHFM
                     RQG"
     CDS             complement(11162..11419)
                     /locus_tag="ctg103_13"
                     /transl_table=11
                     /translation="MEERQVLHVLVDELPDDELVAAMRFLEYLRFRSHDPLRALLDEAP
                     LDDEPVTDEDLAAIQEGLADKARGEVVSHEEAERLLMGSK"
     misc_feature    complement(11309..11311)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     CDS             complement(11449..11679)
                     /locus_tag="ctg103_14"
                     /transl_table=11
                     /translation="FLGRLGALGILAVMVGAIFMVHLPNGFFMNWMGNQKGEGFEYHIL
                     AIGIALAVLVKGSGSLSVDRSMSDKSRYYLR"
ORIGIN
        1 cgcagcacct cttgaagcgc cgcggcctgg cgcttggtga tgacgaggag gggcgagccc
       61 tccgcagtcc agactttctt gtagagcgcc gccgacttgg gcggccgggt ggtgagcacg
      121 aacagatgaa gaatcaccca ccagagcacc cgcggcatct cgatcacccg cggatcgaga
      181 aggaactcgc gcagataccg ccgcagcgcc ggcgaatccg gcgcgtcggg cgtcccgagg
      241 ttggccagga ggacgcccac cgccggcacc tccccgtgct ggaagtcggg ttgaccgaag
      301 tacttcatcg tgagggcgag tctatcgcct acggccggct gtcgagcaat ccgaacacct
      361 cccccacctg ctcccagccg atccgcatca ggaaggtgtt gttcctgccg taggacttgc
      421 tgcccaggat gaagaagccg ggctcggggt tggtgagagt gtcggcgcca tgagaggttt
      481 gggccagaca gtcggagctg ccggctccca ggagagcgcc ggaaagtttg atcgggccgc
      541 aggtggcata gcactcgtgg acttgaagct ggcggtagag cccgtggtcg cccaccgcgc
      601 cggtcaagga gaggatgcgg tccactttga cggcttcagg acccgaaccg ttcctcagga
      661 cgacgtggaa cttgccattc ggtttcgaga tctcctcgac cgcggcgccg cgccgcacct
      721 cgacggctgg cgagacgcct gccgctagcg ccgcggccat tgcggcgagg cccgcgcgtt
      781 ccggcagcgg atcgcccgga tgagtacccc aactcggctc tggattgcgc agcacccaga
      841 tcacctcggt gtccggcgct tcctgcgcca gccgtgagag gtcgcgggcg gcggtctgcg
      901 ccgaatgtcc agcgccagcg aggaggacgg tcttgccagc ccaatccgcc gcttctcgcg
      961 caaagtccgg gatgtcgcgc cggatctcgc cgccgaagtt gcgctctcca ggggcgggga
     1021 tgcctgcgtc ccccagggtg ttgggattcc cccaggtgcc cgtcgcgtcg atcactaagt
     1081 ccgccgactc cgtccactca cggccggcgt cgtccgcgag aagcaggcgg aagggacgcc
     1141 gcccgcgctc ggcggttgcg atctcctcgt gcttgagcaa tccctcgcgg ccgatgccga
     1201 gcacgcgggt gccgaggcgg agatgaggag cgatcttcgg tagcctggcg aggggctcaa
     1261 agagctgttc ggcgagctcg cggccagtgg gacacgcgga gccgtccggc gtctcggcgc
     1321 ccgctgcccc aaggtggcgg cgcatacgag gggagacatt catctcccag ggggtgaaca
     1381 gccggacgtg cccccaggcg cggacgttgc ccgcgatgct ggtcgccgac tcgtacacgg
     1441 tgaacgggaa gccgccgtca gcggcggcga gggcggcttc gaggccggtg gggccgcctc
     1501 ccaggatggc gatacggggc ttggcatcgg tcatgtcatc ttctcctgac gtctttccgt
     1561 ctttcctaga atcgggaagc cgcgcgctcg cgggcgggca ggatctccag acaggtggtc
     1621 caccatccgg tgaggacggt ctcgacgaac tcctcgggca atctctcgcg gcgcatctcg
     1681 gcggccagcc ccgcatgatc gtagcgcaat ggcaacagct cgacgccgag gccctcctcc
     1741 cgggcctcca gcatggcgaa ccagacgtgg atgttgccgt cgttggcggg ccggccgatc
     1801 acgccggcgt taaccacctc cctcccggag gggaggcggc ggtgccagtg caggccggta
     1861 tgcgtgcaaa ggatgccgtc gcaccgattc tggtccagga gcacctccag gaacggcacc
     1921 ggcgaggtgc tttggaagag gaactcgttg acccgccgcg gcgagccgtg gaccagcagc
     1981 agctcccggt tccccacccg cacccggcgc ctgcggggga gcgtccccat ccaggccttg
     2041 aattccggcg agctgttctg ggcggtatag cgataggaga tctcggcgaa gtggttgtcc
     2101 cgagggtcgg tgtagccgca gttgcagtcc tcgcggcccg aggcgaggga ctcctcgtag
     2161 ttcccctgga tggcgagcac cttcccttgg acgaggagcg gccacacttt ttctggattg
     2221 ggaccgaagg cgcccagatc tcccaggcag tagatggcct cggcaccgcg cctcgccgcc
     2281 tcctccagca cctcggccaa ggcgtagtgg ttgctgtaga cgccgccgaa gacggcgatg
     2341 cgggagtagg gtccctcgat cggggtgggg tcgaagaccg gcgccccata gtcccgtaag
     2401 gccgcctcgc gctcctctgg ggtcagcgtc aagccggcct ccgccgccgc ttggcgaaac
     2461 gtggcgaggg ggaccagcct ctctccccag gttgccaggc cccgatgggc ggtcagcttt
     2521 tccggcattc ggcccccgtc aggtcctgca gctcacgccg tagacgtggc acgtccagca
     2581 ggccgagtgc cccagcggaa acgctcccag ggtgtcggcc agggtttcgc ccatcttcgc
     2641 cgaaggctcg ttgaccagga tggggcagac ccatacaccc tggtcggtga ccatccggca
     2701 cgaactgcac tgcaagtggt cccagcctcc ctcaggaacg tcctcctctt tcaagtgctg
     2761 ccagctctcg taggcgccgc cacgctcggc ctcggcgccg atctggaaga ccggcaacac
     2821 cttgagccgt ggccgctcga ttcccatgga gcgcagaagg gcgaagaatt tttccttgcc
     2881 ggagtcggtg atggcctcac ggcagacctc ggtcactgtg atcacagggt tcagcccagc
     2941 ctcgtgcaga ttgcgcgctc caaccagaat gcgctcgaag gtaccagcgc cgcgaatggc
     3001 gtcgttgctc tcggcatcgt agccatcgac ggagacgcga acgtccagcg agtactcggc
     3061 ggcggcggcg agcttcttca ggctggcgca gcgggccggg tcgagcagca ggccgttggt
     3121 cagcaccgtg gcgggcccca cggcgagcgt cgcttccagg atggcctcca tctcgggatt
     3181 gaggaacggc tcgccgccgg tgaagtagta ctcgcgcacg ccgagccgcg acgcctcgtc
     3241 aagataccgc ctcacctctg ccagcgtcag gaactcatgc gtgtgattgg tgggcgagca
     3301 ggagacgaag caatgggtgc aggcaaggtt gcagacggtg ccgcccacct ggaaccacag
     3361 ggtgtcgagc gatttcagag tgacttcagg ggtgttcatg cctttcagga gaatatacgg
     3421 tcttcctcgc actgcggatc aggaccttca tcgtagcctc gggcgaccct gtccggtttc
     3481 cggcttgcgc tatgatctgc ggaccttgaa acgctttctt gccttctccg tgccgcttct
     3541 tctcctcgcc atggccctcg accgctttgc tctcgaagcc gtcggccggg ctcctgatcc
     3601 atccgcgctc tcgccctcgg gagtgacgcg attgctgccg ggctgggtca tgcttgccac
     3661 ctgggtgctg gaagccattg cactctcggc cctctacctt ctcattcagg ggcggggagg
     3721 cgcgcgctgg ctcaacggct tgctgaccgg ctggatcgcc tgggtctttc gcggccccct
     3781 cctcgtggtg acggtggtgg ggatggccgg cctgccccac ggaccctggt gggcgatggc
     3841 gttctcctgg ctcgtgctct acaccttctg cggcctcatc ctcggtggcg ccgcggccgc
     3901 ggcgggcctt cagcaaccct gaacccaatc cggcccgcga gggacttaac cgacaggagg
     3961 gaaggccgca cttgagaatc gcagccgtcg gaaggtctct ccctcctcat tattacgatc
     4021 aggagacgct cctcgcggcg ttacggcggc gttggtcgga ccgctacttc aatctcgaac
     4081 gcctggagcg tctgcacaag aacgttctgg tgggcggccg ccatctggcc ttgccgatcg
     4141 aggagtacga caccttgacc acctggggaa aggcaaacga cgcgtggatc cgggtggccc
     4201 aggaggtggg agcccgggcc gtgctggacg gtttggacaa ggccggactc tcgaccgacg
     4261 acgtggacgc gctgattttc gtcaccgtca ccggtgtcgc cactccctcg atcgacgccc
     4321 gcctgatgaa tctcctggga ttgcggtcgc gagtcaagcg gatgcccatt ttcggcctcg
     4381 gctgcgtggc cggcgccgcg gggatcgctc gggcggctga ctacgttcgc gcctttccag
     4441 accaggtggc cgtgctcctc tccgtcgagc tctgctccct caccttgcag ccggaggatc
     4501 tctccatccc caacctcatt gcttcgggcc tgttcggcga cggcgcggca gcagcggtgg
     4561 tcaccggcgc ggaccggccg cagaccggtc agtccatcgg gacgcggatc gtggacagcc
     4621 ggtcggtctt ctaccccgac tccgagcggg tgatgggatg ggacatctcc gagacgggct
     4681 tcaagatcgt cctttcggcg gacgtccctc tggtcgcccg cgacaagctg cgccccgacg
     4741 tcgattcatt tttggccgag cacggcctca aggtctccga catcgcctcc tgggtctgcc
     4801 accctggggg tcccaaagtg ctggaagcga tgcaggaagc cctcgatctc ccgcccggag
     4861 ccttggatgt gacgtggcgc agcctccagg aagtggggaa cctctcttcg acctcggtgc
     4921 tgatggtgct ggccgagacc ttggagaacc accggccgcc gccagacagc tacggcgtcc
     4981 tgctggccat gggtccgggc ttctgctccg agctggtgct gctccagtgg tgagcgacac
     5041 ccgcatcctc tacaccttgc tggtggcgct ggtcgccctg ggccgcctct tcgagctgcg
     5101 gatcgcctcc cgcaaccgcc agcgcctcct ggcgcggggc ggagtcgagg tggcgcccgg
     5161 gcattatcct tggatggtgg ccctccatac ggcactcctc atctcgtgcc cggtggaggt
     5221 ctggcttctt cgccggccgt tcgtgccctt ccttgccgcg tcgatgcttg tcctcctggt
     5281 ccttgccgga gcgctgcgct ggtgggtgat ccaaaccctt gacggccgct ggaccacccg
     5341 catcgtcgtc ctgcccggcg tgccgccggt cgtcggcggg ccgtatcgtt tcctgcgcca
     5401 ccccaactac ctcgccgtca ttctcgagat cttctcgctg ccgatgattc attcggcctg
     5461 gctcacggcc atcgtcttca gcctggcaga cgccttgctt ctccgagtgc ggattcgagc
     5521 cgaggaagcg gggctctccc gcgtttctgg atacgaagcc gcattcgccg accggccgcg
     5581 gctgatccct gggggagtgc cgggaggagg tggggactga gcgacgaggt gatcctggcg
     5641 ggaatcgcgg aggtggcaag agctcatctc ggctgggacg gcgtcgtcac tccggacctg
     5701 cgcctgatcg aggacctgcg gctcgattcc atccgcctcc tcaccctggc ggccgaggtg
     5761 gaaaaccgct ttcgcgttct cctcgacgag ggagacgaag cgggaatcga gacggtggga
     5821 gatctggtcg ccgttgtgcg ggggaagctc gatgcctgag aggccggaag gaattctcga
     5881 ttggctggag caggccggcc gccggccgga aggggggctg cgcttcgtcg atcggaccga
     5941 gacggccacg tggtttggtt gggccgagat tcgcgaacgg gccagggcag cctgtggcgg
     6001 catgcaggcg ctgggaatcg agcgcggcgc ccgcgtggcc ctgatcttcc ccaccggcat
     6061 cgacttcttt gtcgctttct tcggcgccct gctggcgggt gccgtgccgg ttcccctcta
     6121 tccgccggcg cgcctggggc gaagagagga gtacgtacgc cgaacggctc agctgctgga
     6181 gcggtcggga gcgcgattga tcctgtccga atcccgtctg tgccgaatcc tcggcgacgc
     6241 cttgcaagaa acccatctgg cgctaggttg ccgcacgctg gaagatctcc ctgtcgagtc
     6301 cccccggaca atcctggccg ccccgtcgga cctcgcactc gtccagttct cctccggcac
     6361 cacgggcgat cccaagcctg tggcgctcag tcaccgcgcc gtcgcggccc aggcggagat
     6421 cctcgccggt ttctggccgg actcgccgga gcagcgccag agctgcgtct cctggttgcc
     6481 gctctaccac gacatgggat tgatcggctg cgttttcccc gccctggcgc gcgacgcgac
     6541 gctgacgctt ttcgccccgg agctgttcgt cgcctgcccc gctctctggc tgcggaccct
     6601 ctcgcgctat cgggcgacga tctcgccggc ccccaacttc gcctacaacc tctgcctgaa
     6661 ccgggtgtcg gacaaggata tggaaggagt ggatctctcc ggctggcaga ccgctctcaa
     6721 tggcgccgag tcgatctcgc ctggggtgct gcaggcgttc tgcgagcgtt tcgcggcctg
     6781 gggtttcagg cccgaggcca tgactcccgt ctacggcctg tcggaggcgg ccctcgccgt
     6841 caccttctcc gacctggccc ggccctatcg cgtcacccac ttcgaccgcg aaaagctggc
     6901 tcgcgagggc cgggctcggg cttcggtgaa cgggcgggag atcgtctcgg tgggccggcc
     6961 ggtccccggg ttccgcctgc ggatcgtggg cccggaaggc tgtgaccttc ccgccggcga
     7021 tgttggccaa gtctggattc agggcccctc cctgatggag ggctacctgg gtgatccgga
     7081 agccacggcg aatgtgctgc gcgacggctg gctggacacc ggcgatctgg gcttccaata
     7141 cgccggcgag ctgtatttgg ccggccgcgc caaggacgcc gtcatcctgc gcggacgcaa
     7201 ccacgcaccc gaggagatcg agcgggcggt ggaagaggtg cccggccttc gcacctccag
     7261 tgccgtcgcc gtgagctggc tgccggaaga tgctcccggc gaagagctgg cgcttttcgt
     7321 ggaagcctcc cggcaggcgg cgccggaaga gctcgcggcc ctgcccgacg cctgccgcga
     7381 agccgtcctc ggcgcgaccg gcttggccgt ggaccgcctc gaggtgctgg cgcccggcac
     7441 cctgccgcgg acctcatcgg gcaagctgcg ccgtggggag accctgcgcc tgtaccttgc
     7501 cggcgagctg gccggcctgg aatccgcggc ctctctgcgc ttgtcaggag tcctcgcatg
     7561 accgacctgc tggtgatcgg cggcggcccc gcggggttgg cgaccgcaat ccgggcgcgc
     7621 ctcgccggac ttacagtcac agtgctcgac cgcgctcggc cgcccatcga caaggcctgc
     7681 ggtgaggggc tgatgcccga tgccgtgaag cgcttgcgag agatcgggat tgagccccgg
     7741 ggctttccgt tccgtggtat ccgctacatc gacggcaacc tcatggccga ggggcacttt
     7801 cccggctctg gcggattggg cgtgcgccgc accgagttgc acgccgctct agtccggcgg
     7861 gcggagcagg tcggggtcga ccttcgctgg ggagtaaagg ccgaagggct cacggacgaa
     7921 ggagtccgga cggaccaggg aatcctcgcc gctcgctgga tcgtgggggc ggatggcctg
     7981 cgttctcagg tgaggcgctg ggcccgcctc gacggaaagt tgagccctct gcgtcgcttc
     8041 ggaattcgcc ggcatttcgc cgtgactcct tggagcgact gcgtcgaggt ccactggggg
     8101 ccggagagcg aggcctatgt gactccggtg agcagcgacg aagtgggaat cgccgtgctc
     8161 tggagcggac agaaagccgg ctttgacggt ctccttgaga gtttcccgac tctgaaggag
     8221 aaggtcgaaa acgcgcctgt tgcctcccgc gaccgcggaa tgggccccct ccggcagcag
     8281 gtgagggcag tgatcaacgg tcgcgtggcc ctggtggggg acgctgccgg ctatcttgat
     8341 gccatcaccg gcgaagggct tgccgtcact ctccaagagt cggccgctct ggtggaggca
     8401 ctgacgaggg gcgatctctc ccgctattca gccgcccatc ggcgaatcaa ccgcctaccc
     8461 aatttcatga cgtcgatggt gctcggcctc gagcggcgtc cccgcctgcg ccggcgcgtt
     8521 cttcgcgccc tcgccgccga gccctcgctc ttcgcccgcc tgctgggcat ccacgcccgc
     8581 accctgccgc ctcgggattt tggcttcgag ggcgccctcc gcctggcctg gagactggtc
     8641 gcagcctaac aaaggagaac tcgcatgcac tgccgcagga tcgctctctc catcgtgtcc
     8701 gcgctggcct tcgcttcggt cctctctgcc gagcaagtga ctttcgagct cgaccccgcc
     8761 gccaccacca tcgagttcac cttcggcgcc accctccaca cggtggacgg caccatccgt
     8821 gccaaggaag ggacgatcca cgtcgactcc gaaaccggcg ccgccaccgg ccgcatcgtc
     8881 atcgacgcca ccagcgccaa gaccggcaat gcccgtagag accgcaagat gcacgagaag
     8941 atcctggaaa gcgagcgata tcccgagatg atcttcgaga tcgagcggtt gagcggcaag
     9001 ctcaacccca tcggccaaag tgagatcgag cttcacggca acctggaaat gcacggcacc
     9061 cgcctgccca tcggtctgcc cgcgaccgtc atgactaccg acggcaagac ggtgactggc
     9121 acggggaacc tcatcctctc gtatctgaaa tgggggctcg ccgatccgag cgtctttttg
     9181 ttgcgagtgg aaaaggaagt ccacgtcact gtgaaggccg ccggctcaat ccggactgag
     9241 ggcgcccctc cgacgcaata gggagattct cgcgtgttct cgctgtacac cgcccgcctg
     9301 tgtgaatttg gaaagtgcca tccgccggcc agattatttt agattgagcc tgcattcccg
     9361 attctgagac gcccagaggg tagcgccagc taccccgtgg ggcgtctccg agagcggcga
     9421 catcgctaca atcttccaag cgccgcgcgg acgctgagcc ctccgagaag gaatccctgg
     9481 accacccaat ctgtttccgc agtgtccgct gtaacaccaa gaatccgcaa atctggcgta
     9541 aactactcag tccttatgaa gaagcccgcc cacgactggt ccccttttct ttccgacgaa
     9601 cgtccggtgg agcggttctc gccccatggg cgataccggc tggcgttggc ctatgccaac
     9661 agctaccaca tcggcatgtc gagcctgggg ttccagcgcg tctacgagct gatccaccgc
     9721 cggccggatt ggtcatgcga gcgcctgttt acggacggcg tcggcatgcc cgtctcgctc
     9781 gagacccgca ggtcgatgaa cgacttcggc tgcatcgcct tctccgtctc cttcgaagag
     9841 gattacgtca atctcctcca gatgctggac cgggcccgca tccccgtccg gcggcgtgac
     9901 cgcggcccgt gggatccggt gatcgttctc ggcggctcct gcgccgcgat caatccgttg
     9961 ccgatgtccg agttcgtcga cgtcttcacg ctcggcgctg cggaaaacgt ccttccccat
    10021 cttcttgacg cattggaagg agaggaaggg cgggaggcgg tgatcgagcg tcttgccgct
    10081 ctggacggct tctacgttcc cgcctttcat catccggaag acgatggaga cgagctgccc
    10141 aagctcaata agctggagct caccgaagag cagatgaagc agacgggcaa cctgccgacc
    10201 acctgcatcg tcacgccgcg aaccgagttc tcggagaagt tcctcatcga gatgtcccgt
    10261 ggctgtcccg agaagtgccg ctactgctgg gcgaccttcg gcatggggcg cttccgctgg
    10321 catcccacgg atgagatcct cgccgcgctg gagcgggcca agccggtgac caatcaactc
    10381 ggcttcgtgg ccacggccgt cggcgatcat ccggacattg agcccattct gcgcgaagcc
    10441 aacaagctcg gtttccgcac ctcggtctcg tcgattcgca tccccgccgt caccgagggc
    10501 gtgctcgaag ctctccacgc ctcgggcgac cgttccatca ccctcgctcc cgagacgggt
    10561 acggacgagt tgcgggtgaa gatgggcaag ccgatcaaaa acgagtttct gctggagaag
    10621 atccgcctca tcttccgcca cggcttcacc cagctcaagc tctacttcct gattggcttg
    10681 ccgggcgaaa ccatggagga catccaaggc atcctggacc tcgccgcccg cgcccgcgcc
    10741 gtcatgctcg aagagctgcc gaagaagggg atgatcggca acatccatct cggcaccaac
    10801 gtgttggtgc cgaaacccta cacaccctgg cagcgcgagc ccatggacga cgagcggagc
    10861 ctcaaggaaa agatcgcgat tctcaagaag ggcgtctcca gaatgcccaa catctccctg
    10921 ggctccatct ccgtccggca ggccatctgg cagacctaca tcagcaaagc cggaagcgac
    10981 gccgccgacg cgatcgaagc tgcagcccgc ggcgaatcga tcagctcagt tcttcaccgc
    11041 ttcgcccccc agatccatcc cgaggtctac ggccggctgg agggagattt gcggtggcat
    11101 tttatgcggc aggggtaggg cttttttgtc agaccggcat taaccggtct agcatgccgg
    11161 ttcacttgga ccccatgagg aggcgctcag cctcctcatg cgagacaact tcccctctcg
    11221 ccttgtcggc gaggccttct tgaatagcgg ccagatcctc gtcggtcacc ggctcgtcgt
    11281 ctaggggagc ctcatcgaga agtgcgcgta aagggtcgtg actccggaat cgaaggtact
    11341 caaggaagcg catagccgct accagttcgt catcagggag ctcgtcgacc aaaacatgga
    11401 gaacctgtct ttcttccatg tctccattct acacggccga ggcctaccct accgcaggta
    11461 ataccgcgac ttatccgaca tcgacctatc gaccgacaaa ctcccgctgc ctttgacgag
    11521 cacggctagg gcgatgccga tggcgaggat gtggtactcg aagccttcgc ccttctggtt
    11581 gcccatccag ttcatgaaga agccgttggg taggtgcacc atgaagatgg cgcccaccat
    11641 gacggcgagg attcccagcg ctccgaggcg gcccaggaa
//
