LOCUS       c00217_3300010..       13690 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300010401.a:Ga0134121_10003231.
ACCESSION   c00217_3300010..
VERSION     c00217_3300010..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 06:52:58
            Original ID  :: 3300010401.a:Ga0134121_10003231
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13690
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13690
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3674:4889](+)"
                     /cutoff="20000"
                     /detection_rule="ladderane"
                     /neighbourhood="20000"
                     /product="ladderane"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3675..4889
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="ladderane"
                     /neighbourhood="20000"
                     /product="ladderane"
                     /protocluster_number="1"
     cand_cluster    1..13690
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="ladderane"
                     /kind="single"
                     /product="ladderane"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..13690
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="ladderane"
                     /region_number="1"
                     /rules="ladderane"
                     /tool="antismash"
     CDS             complement(2..796)
                     /locus_tag="ctg217_1"
                     /transl_table=11
                     /translation="MNLTPEQVADILVRQGFLKPEQGEAIKQEARALPRSMRNANAFEQ
                     RAVAYELVLQMRLPNQRDSGAALGEMDVALAIAADAKLDHVRIDALNLNADLIESKMSR
                     PFARRHRMIPLDMADGKLRVACANPYDIEGIDSFRRIAGRDIQLVVASEPDILKAITEF
                     YGLRHSVKRAERDLSAGIDLGNLEQLVRMKNEAEIESSDQHVVNAVEFMLQHAFESRAS
                     DIHVEPKREDSLIRFRIDGVLHDIQKMPKIVHAAVTSRIKTMS"
     CDS             843..1733
                     /locus_tag="ctg217_2"
                     /transl_table=11
                     /translation="MSIPLAALLLVVCSSLGWSGFDLLRKLLVREVAPVALLLLLTLGS
                     VPLFAAWVWIDGVAAPAPGYLAPALGSVILNVVSNLLFLHGVRVAPISVAIPLLSLTPV
                     FTMLWAIPLLGERPSAAGVAGILLVIAGAIWLNWPRRRADPAETPASGDPRRALTGAAM
                     VATTALLWSLTSSLDKMAVERAGAPLHSLVLTGGVALAVFGVLALQGGLGELGGVRRIP
                     GLLVLALVISSAALGLQLLAMPKVFVGTIETVKRGIGNCMALVYGRLFFREVITPSKIL
                     AVGLMAAGVGLILGF"
     CDS             1818..2960
                     /locus_tag="ctg217_3"
                     /transl_table=11
                     /translation="MALFNPKSKIQNPKSFRAAALLLLVPVLACGAAKPHLGRIKLPPG
                     FSIAVYSQAVPGARSLAQSPNGIIYVGTRGQGKVYALVDKNKDGRADQVFTIASGLSSP
                     NGVAWRDGSLYVAEISRTLRFDHIDDHLASPPKPVVVTDAYPSDSQHGWKFIRFGPDGK
                     LYVPVGAPCNICEPGEPFASITRIDPLAAKKPEIVASGIRNTVGFDWQPGTGVLWFTDN
                     GRDMMGDDMPPDELNRAPKAGLHFGYPFCHGGRFPDPELGGKHPCSQFVPPAIALGPHV
                     AALGMRFYTGTMFPPRYRGQIFIAEHGSWNRSDPIGYRLTLVRVEGDRAVSYETFAEGW
                     LGHFGVSGRPVDVEVMPDGALLVSDDYAGAVYRITWAANP"
     CDS             3397..3678
                     /NRPS_PKS="Domain: PP-binding (10-77). E-value: 2.9e-11.
                     Score: 35.5. Matches aSDomain:
                     nrpspksdomains_ctg217_4_PP-binding.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg217_4"
                     /sec_met_domain="PP-binding (E-value: 6.3e-12, bitscore:
                     35.5, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSNAEEIRTRIKQIIANVAGLNAGRINDDAKLREDLKLDSLSLL
                     EIGVDVDLAYKLELPDERYKEIDSLPAMVDLVQQRLGEREMQPKAVLG"
     aSDomain        3427..3627
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg217_4_PP-binding.1"
                     /evalue="2.90E-11"
                     /label="ctg217_4_PP-binding.1"
                     /locus_tag="ctg217_4"
                     /protein_end="77"
                     /protein_start="10"
                     /score="35.5"
                     /tool="antismash"
                     /translation="RIKQIIANVAGLNAGRINDDAKLREDLKLDSLSLLEIGVDVDLAY
                     KLELPDERYKEIDSLPAMVDLVQ"
     aSModule        3427..3627
                     /domains="nrpspksdomains_ctg217_4_PP-binding.1"
                     /incomplete
                     /locus_tags="ctg217_4"
                     /tool="antismash"
                     /type="unknown"
     CDS             3675..4889
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (4-401). E-value:
                     1.5e-61. Score: 200.3. Matches aSDomain:
                     nrpspksdomains_ctg217_5_PKS_KS.1"
                     /NRPS_PKS="type: PKS/NRPS-like protein"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ladderane: ladderane"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 378.9; E-value:
                     5.6e-115)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg217_5"
                     /sec_met_domain="ladderane (E-value: 7e-129, bitscore:
                     419.7, seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSRIAVTGLGLVTPIGEGRQEVWEGLLAGRSGFAPVESFDTRGF
                     SAHLGAEVRGFDPAPWVRRQDPAALGRASQLAIAAARQALDDAGLDPEALEPERAGVAM
                     GTTSGEPREVERFDDKYLAGELEQVGDEFMGLYPCHMIAAHVARELGFAGDNTMIPTAC
                     AAGNYAIAHAVDVLRAGRADVMLAGGADSFSRITYTGFARLGAIAPERCQPFDRNRKGM
                     IPGEGAAVLVLEPLERALARGARVYAELAGYGLSCDAHHMTAAHPEGDGAARAMQRALA
                     DAGAVPADVSYISAHGTGTPTNDRLETLAVKRVFGAAAKNTPMSSIKSMIGHTMGAASA
                     IEAAVCALAVALDRIPPTMNLEEPEEDLDYVPNTARDLRVVLAMNNAYAFGGNNASVIL
                     RKHEA"
     aSDomain        3687..4877
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg217_5_PKS_KS.1"
                     /evalue="1.50E-61"
                     /label="ctg217_5_PKS_KS.1"
                     /locus_tag="ctg217_5"
                     /protein_end="401"
                     /protein_start="4"
                     /score="200.3"
                     /tool="antismash"
                     /translation="IAVTGLGLVTPIGEGRQEVWEGLLAGRSGFAPVESFDTRGFSAHL
                     GAEVRGFDPAPWVRRQDPAALGRASQLAIAAARQALDDAGLDPEALEPERAGVAMGTTS
                     GEPREVERFDDKYLAGELEQVGDEFMGLYPCHMIAAHVARELGFAGDNTMIPTACAAGN
                     YAIAHAVDVLRAGRADVMLAGGADSFSRITYTGFARLGAIAPERCQPFDRNRKGMIPGE
                     GAAVLVLEPLERALARGARVYAELAGYGLSCDAHHMTAAHPEGDGAARAMQRALADAGA
                     VPADVSYISAHGTGTPTNDRLETLAVKRVFGAAAKNTPMSSIKSMIGHTMGAASAIEAA
                     VCALAVALDRIPPTMNLEEPEEDLDYVPNTARDLRVVLAMNNAYAFGGNNASVILRKH"
     aSModule        3687..4877
                     /domains="nrpspksdomains_ctg217_5_PKS_KS.1"
                     /incomplete
                     /iterative
                     /locus_tags="ctg217_5"
                     /tool="antismash"
                     /type="pks"
     CDS             4894..6180
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (54-381). E-value:
                     1.9e-30. Score: 97.8. Matches aSDomain:
                     nrpspksdomains_ctg217_6_PKS_KS.1"
                     /NRPS_PKS="type: PKS/NRPS-like protein"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) t2fas"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 210.7; E-value:
                     6.4e-64)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg217_6"
                     /sec_met_domain="t2fas (E-value: 2.6e-70, bitscore: 226.7,
                     seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MALENRRRVVITGAGCLSCLADSPGGLHAALVAGHSGLKAIELFS
                     TDAIGCHQAGEIRPFDAQAYLPDRNLRPIDRTSRLLLVAAGKALAASGRPLEVAERDDG
                     EIGLVLGTTFCSLRTIAEFDRRNLQLGPSYASPLDFANSVINAAAGQAAIWFGLRGLNS
                     TISAGAASGLAAVGYATDQIRGGRANALLAGGAEELCFESFFGHYQAGRLCGSAGNRNE
                     EKGEVPIPFDARRNGFALAEGAALMMLEDAAAAAERGAPVLAEVLGHGSGFDPLGTPES
                     AARAVARAIRLALEEAGLGPLDVDALSAGANGSVDADRWEAAGVAAALGARAEILPVTA
                     VKSMLGEALGASGGLQLVALLGTLEDGVLPGILGLEQTEEGFPFPGASPNARRLPGHRG
                     SGAVTALATTLSADGHAWAVLLGSWRGSA"
     aSDomain        5056..6036
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg217_6_PKS_KS.1"
                     /evalue="1.90E-30"
                     /label="ctg217_6_PKS_KS.1"
                     /locus_tag="ctg217_6"
                     /protein_end="381"
                     /protein_start="54"
                     /score="97.8"
                     /tool="antismash"
                     /translation="GEIRPFDAQAYLPDRNLRPIDRTSRLLLVAAGKALAASGRPLEVA
                     ERDDGEIGLVLGTTFCSLRTIAEFDRRNLQLGPSYASPLDFANSVINAAAGQAAIWFGL
                     RGLNSTISAGAASGLAAVGYATDQIRGGRANALLAGGAEELCFESFFGHYQAGRLCGSA
                     GNRNEEKGEVPIPFDARRNGFALAEGAALMMLEDAAAAAERGAPVLAEVLGHGSGFDPL
                     GTPESAARAVARAIRLALEEAGLGPLDVDALSAGANGSVDADRWEAAGVAAALGARAEI
                     LPVTAVKSMLGEALGASGGLQLVALLGTLEDGVLPGILGLEQTEEGF"
     aSModule        5056..6036
                     /domains="nrpspksdomains_ctg217_6_PKS_KS.1"
                     /incomplete
                     /iterative
                     /locus_tags="ctg217_6"
                     /tool="antismash"
                     /type="pks"
     CDS             6177..7397
                     /locus_tag="ctg217_7"
                     /transl_table=11
                     /translation="VSSEPVPFRASGAGDLVPRFEDQGHSAEAVAARRAWVEERTGARL
                     EQVGAASIPAEAWRGNVENPVGAVQVPLGVAGPLRVEGEHARGVFYVPLATTEGALVRS
                     YERGMMTLTRAGGATVRMLADENRVSPVFVFDGVAEAAAFARELPELFGALKREAESTT
                     RHGRLLRVEPLALGREVAVHFVYWTADAHGMNMIVKATDHACRWLVAQGHAGRYYLFSG
                     AESEKRASGSLFAGGKGKKVTAGARISPRLMRAYLHTTPAAMADLWQRTVLGHLQAGAL
                     GYNGHIANGLAALFIACGQDVANVANSAVGITSFEVLPGGDLYASVTLPSLTVATVGGG
                     TGLGTARECLEMLGCAGEGGAPKLAEITAAMALAGELSMGAAVASGEFVAAHETYGRNR
                     PDEDDSG"
     CDS             7394..8950
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222:dehydrogenase (Score: 246.3; E-value: 1.2e-74)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg217_8"
                     /transl_table=11
                     /translation="MKRLFRGLRRPPNPSYDAVVIGSGIGGLITANLLAKDGLKVLLVE
                     QHYMVGGYCSTFRRGGYTFDAATHFYPLLGNPETLTGRLLVELGTATRWVKMDPVDTFH
                     FPDGTRFAVPADFELYLARLKAEFPHEVRALDKFFAAVREVYLPGLVHYFHGRPAEQLP
                     RLAQYRELTVKDALDRWFHDPKLKLLLTADCPHWGSRPGRTSFVFDSMLRLSYFLGNYY
                     PQGGSQAFADDLARCFEQRGGHILTSTLARRIVVEEGEARGVELEVLRGHVLPQWRSGV
                     VKSGVVISNADLLLTLERLVGPRHLPPDAVEPLRRLRTTFPCWLTHLGLKGVPANVLAE
                     AQGYHWRSWDMERVGRDALCFKLFAPTLFEPSLAPGSEQILIVQKVQELDYDAVDDWPR
                     HKREVEAFVFANLERVIPGIGAQIAVRSSASAYTSGRFTLNSRGAMLGWEMSPEQLGAG
                     RPRPETAIRNLHCVGHWTQPGGGVTPVIVSAQRVAQTVLRGAAGSESPGLPIRMAAAGI
                     R"
     CDS             8962..10503
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1141:acyltransferase (Score: 94.8; E-value: 7.9e-29)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg217_9"
                     /transl_table=11
                     /translation="MACSFEDSGVAIFRPRLIPGGAMPDLAAAADDLAACARSQPARLV
                     LLSSAAALDPSHHNPGFVAETYRPEGTNPIARAWRELEALAAAKLPQAERIVLRPAPVA
                     ARKDADFISRRLAGASAVVPPGFDPALQFLAPADLEAAVCCAVERGAGRPGLFHVAPRG
                     AVPLRTAMRLAGVRCLPLAWTGAGGENDYLRHNWTVSGAKIERELGFVPKTTSAAAVLA
                     AFATAGSAVPQPDDFGLDLGYIAAYERTLFRFLHDLYWRIEVVGTENLPREGGAVLTGV
                     HRGFMPWDGVMALVAVHRAVGRVPRFLIHPCLIKPPFLANYMIKLGGIVANQENADWVL
                     SRGDLLGMFPEGIHGAFTMYRDAYKLGKFGRDEYVKMALRNRVPLVPFVTVGSAEIYPI
                     WGRLDWKWVKRATEWLFLPLGPNFPFPGLPLPSKWHTRFLAPIPVQEQYGPEAADDPAV
                     VKAISAEVRARMQAAIDEMLARRKSIFWGTIFDRIETEPGSLDVVRPGSLPRVGG"
     CDS             10463..11356
                     /locus_tag="ctg217_10"
                     /transl_table=11
                     /translation="MSFDPVAFRELAGKLRAFALFRGAGMAPERALARAARLNPWSRLF
                     VLEGIGYARGNAGWPPQSSEDGALIPLTMGWGLALAVRSFRSARARITPEESLRSFAAA
                     CRELAPPGLTGVAFEGLGLVARLQWAKAVPALSRALGEMDGGLEARFWHGVGRGLFFLP
                     GDTFLWGSSAGRALARALHEPPAGLPRANTLAGLAMAITLICLPHPRVIDRFLSRHSGQ
                     IDDAASFQYGIAAAALVWCRAAGRDELLQRLLSHPSQTPEHWQAWVRRPCEQALGESFP
                     VLVRDGGWDDLFRVMR"
     CDS             11353..13689
                     /locus_tag="ctg217_11"
                     /transl_table=11
                     /translation="MKRRRFLIFGLLAVVIFLSGGWLTLDRLDRRGREFYEAGRAVVAA
                     LDLLAGDLSRRDLAAVGNVYSPDFHGSSLGLASFQPAAEKDGIATLRLIPGKGKADRGS
                     AVAEWRAYLDGFQSIEELGLHLHRVEAWEAGGEVTAMVRFEVIGTLKGHARSGIDRALF
                     RMCFVPGGNGLQIAEASPVEGERLEADRPQFEEVGHAAGIDFQNRYYPPFLTTPLRFGM
                     IRYGPGGISAVDFDNDGLYDLFIPDGVESRLFHNRGDGTFEDVTAASGLAGLDGVSVGV
                     FADYDNDGWKDLFVSRTFKPNQLFHNDGPDASGHIHFTDVTAKSRLGEDCCTTVASWGD
                     YDNDGRLDLYVGRYLDPRKKIPTTFYARNGEGNRLYHNNGDGTFTDVTAAAGVGDTGLC
                     LGSVWGDYNDDGRPDLYVVNDFGRKTLYRNNGDGTFTDVTVASGTLDYGAGMSASFGDY
                     DNDGKLDLYVANIRSEHSWLAESPTVWRYMANSWRQGVWRTDMPLYFQIFRQSGSRFVQ
                     VFQQMASGNTLLRNKGDGTFEDVTWKADANPVGWFWGSGFGDFDNDGFLDVYSADGWVY
                     NDKGTELELDFLNNVVGNQAEYKKGTFFDPKQFGRLSWHGWERNRHLLNRGDGTFQEIG
                     RPAGSDLILNSRGVALADLWNRGVLDIAVAASADRHALLRNEVGQAGQRRHWLEIELRG
                     VKSNRDAVGARAVVRAGGKTLTREVVAGDGYASQNMLRLHFGLGEPGTVDELTVRWPAS
                     GTVQRFRNVPADRIVQLTEGGSLQPF"
ORIGIN
        1 gcgacatcgt cttgatgcgg gaggtgacgg cggcgtggac gatcttcggc atcttctgga
       61 tgtcgtgcag cacgccgtcg atgcggaagc ggatgaggct gtcctcgcgc ttgggctcga
      121 cgtggatgtc gctcgcccga ctctcgaagg cgtgctgaag catgaactcg acggcgttga
      181 cgacgtgctg atccgaggac tcgatctcgg cctcgttctt cattcgcacg agctgctcga
      241 ggttgccgag gtcgatgccg gccgaaagat cgcgctcggc ccgcttgacc gagtggcgca
      301 gaccgtagaa ctcggtgatc gccttgagga tgtccggctc ggaggcgacg acgagctgga
      361 tgtcgcgccc ggcgatgcgg cggaaggagt cgatcccctc gatgtcgtaa ggattggcac
      421 aggccacccg cagcttgccg tcggccatgt cgagggggat catgcggtga cggcgggcga
      481 acggccgcga catcttggat tcgatcaggt cggcgttgag gttcagggcg tcgatgcgca
      541 catggtcgag cttggcgtcg gcggcgatgg cgagggcgac gtccatctcg ccgagggcgg
      601 cgcctgaatc gcgctggttg ggtagccgca tctgcaacac caactcgtaa gccacggccc
      661 gctgctcgaa ggcattggcg ttgcgcatgc tgcgcggcag ggcccgggcc tcctgcttga
      721 tggcttcgcc ctgctcgggc ttgagaaagc cctggcgtac caggatgtcg gcgacctgct
      781 caggcgtgag gttcattgag ggtgcagttt agcggaactg ctagactccg gcacaccttt
      841 ccatgtccat tccccttgcc gccctcctcc ttgtggtttg ctccagcctc ggttggtcgg
      901 ggttcgacct gctgcgcaag ctgctggtgc gcgaggtggc gccggtcgct ctgcttctgt
      961 tgctgaccct gggctcggtg ccgctgttcg ccgcctgggt gtggatcgac ggagtggcgg
     1021 ctccggcgcc cggttacctg gcgcccgccc tgggctccgt aattctcaac gtggtcagta
     1081 acctgctgtt ccttcacggc gtgcgcgtcg ccccgatctc cgtcgccatt cccctcttgt
     1141 cgctgacgcc ggttttcacc atgctttggg ccattcccct gctcggcgag cggccgtcag
     1201 cggccggggt ggccggcatt ctgctggtga tcgccggtgc catctggctc aactggcctc
     1261 ggcggcgcgc cgatccggcg gagacgccgg cgagcggcga tcccaggcgt gcgctcaccg
     1321 gggcggcgat ggttgccacg acggccctct tgtggtcgct tacgtcgtcg ctggacaaga
     1381 tggcggtgga gcgggcgggc gcgccgctgc acagcctggt gctcaccggc ggagtggcac
     1441 tcgccgtttt tggagtgctc gctctccaag gggggctcgg cgagctcggc ggcgtgcgcc
     1501 gcattccggg gctcctggtc ctcgccctgg tgatctcctc ggcggccctc gggctgcagc
     1561 tcctggccat gcccaaggtc ttcgtgggca ccatcgagac ggtgaagcgg gggatcggca
     1621 actgcatggc cctggtctat ggccgactgt tctttcgtga ggtcatcacg ccctcgaaga
     1681 tcctggccgt gggtctgatg gcggcgggag tggggttgat cctgggattt tagattttgg
     1741 attttagatt ttggattgag gagggataga ccggtgcatg attcttgctt cgggctgata
     1801 cggggagact gatcgccatg gcactcttca atccaaaatc taaaatccaa aatccaaaat
     1861 cgttccgcgc cgcggcgctg ctcctcctcg ttcccgtgtt ggcttgcggc gcggccaaac
     1921 cccacctcgg ccgcatcaag ctgccgccgg gtttttcgat tgccgtctac tcgcaggcgg
     1981 tgccgggcgc gcggtcgctg gcgcagtcgc ccaatggaat catctacgtg ggtacaaggg
     2041 gtcaggggaa ggtctacgcc ctggtcgaca agaataagga cggtcgggcc gaccaggtgt
     2101 tcaccatcgc ctccggcttg agctcgccca acggcgtcgc ctggcgcgac ggctcgctct
     2161 acgtagcgga gatctcccgc accctgcgct tcgatcacat cgacgaccac cttgcaagtc
     2221 cgcccaagcc ggtggtggtc accgacgcct atcccagcga cagccagcac ggctggaagt
     2281 tcatccgctt cggcccggac ggcaagctct acgtgccggt tggcgcgccg tgcaacatct
     2341 gcgagccggg ggagcccttt gccagcatca cccgcatcga cccactcgct gccaagaagc
     2401 ccgaaatcgt ggcgagtgga attcgtaaca ccgtgggctt cgattggcag cccggaaccg
     2461 gcgtcctatg gttcaccgac aatggccgcg acatgatggg cgacgacatg ccgcctgacg
     2521 agctgaatcg cgctcccaag gccggcctcc acttcggcta tccgttctgc catggcgggc
     2581 gttttcctga tcccgagctc gggggcaagc atccgtgctc gcagttcgtg cccccggcca
     2641 tcgccctcgg tccccacgtc gccgccctcg gcatgcgttt ctacaccggg acgatgttcc
     2701 cccctcgcta ccgcggccag atcttcatcg ccgagcacgg ctcgtggaac cgcagcgatc
     2761 caatcggcta ccggctcacc ctggtgcggg tggaaggcga tcgcgccgtt tcttacgaga
     2821 ctttcgccga gggttggctg ggtcacttcg gtgtttcggg gcggccggtg gacgtggagg
     2881 tgatgcccga cggcgccctg ctcgtctccg acgactacgc cggagcggtt taccgcatca
     2941 cctgggcggc gaacccgtaa ttaaccgcaa tatcaaacga atgctctcaa ggttgatgcc
     3001 ctgagcgagc gatatccgcc ttggtaacaa gatcgacggt tggaacgcct gttctcctgc
     3061 gaatccgcgg gttcgcctgg agcgtaccct tcgatggggg aagaacggcg atgcagagct
     3121 cgactgccag gaggctggag attgctgacc gaagaccgct cgcaaactct ttcttttagt
     3181 gcatgccatc aagaattgtc gccagactct gtaacccctt cgcccacatc cattgaccgg
     3241 cgaaagagcg taaaatgaga agcaggagcg ggagcctcgt tcaattgcag tcgtgcactg
     3301 cttgcattaa ctaaggaagg gaagcctgga ttccgagacc tctggtgagg ttcgatggag
     3361 tccgctgttc ccttaccgcc aggacggagg atctgaatga gtagcaacgc cgaagagatc
     3421 agaacccgaa tcaagcagat catcgccaat gtcgccggtc tcaatgcagg ccgtatcaat
     3481 gacgacgcca agctgcggga ggacctcaag ctggactcgc tgtcgttgct cgagatcgga
     3541 gtggacgtgg atctcgccta caagctcgag ttgcccgacg agcgatataa agaaatcgac
     3601 agcctgccgg cgatggtgga tctcgtccag cagcggctcg gcgagcgtga gatgcagccg
     3661 aaagcggtac tgggatgaaa tcgcggatcg cggtgaccgg cctcggcctg gtcaccccaa
     3721 tcggagaggg gcggcaggag gtctgggagg ggcttctcgc aggccgcagc ggcttcgctc
     3781 cggtagagtc attcgacacc cgcggcttca gcgcccacct gggtgctgag gtccgcggtt
     3841 ttgaccccgc gccgtgggtg cggcggcagg accccgcggc gttgggccgc gcctcgcagc
     3901 ttgccatcgc cgccgcccgt caggccctgg acgacgcggg actcgatccc gaggcgctcg
     3961 agccggagcg ggcgggagtg gcgatgggca ccacctccgg cgagccgcgg gaggtggagc
     4021 gcttcgacga taaatatctg gccggcgagc tcgagcaggt gggcgatgag ttcatggggc
     4081 tttatccctg ccacatgatc gccgcccatg tggcgcggga gctgggtttc gccggcgaca
     4141 acaccatgat ccccaccgcc tgcgcggcgg gcaactacgc tatcgcccac gccgtcgacg
     4201 tgctgcgcgc cggccgggcg gacgtcatgc tggccggcgg cgccgactct ttttcacgca
     4261 tcacctatac gggctttgcc cgccttggcg ccatcgcgcc ggagcgctgc cagcccttcg
     4321 accgtaaccg caagggaatg attcccggcg agggagcggc cgtgctggtg ctggagccgc
     4381 tggagcgggc gctcgcccgc ggcgcccgcg tctacgctga gctggcgggc tatggcctgt
     4441 cctgcgacgc ccatcacatg acggcggccc accccgaggg cgacggtgcc gcccgcgcca
     4501 tgcagcgggc cctcgccgac gccggcgccg tgcccgccga cgtcagctac atcagcgctc
     4561 acggcacggg aacgccgacc aacgaccggc tggagaccct ggcggtgaag cgggttttcg
     4621 gcgcggcggc gaaaaacact cccatgagct cgatcaagtc gatgatcggg cataccatgg
     4681 gcgcggcctc cgccatcgaa gccgcggtct gcgcgctggc ggtggccctg gaccgcattc
     4741 caccgacgat gaatctcgag gagccggagg aggatctcga ctacgtgccg aacacggcgc
     4801 gcgatctccg ggtggtgttg gcgatgaaca acgcctacgc cttcggcggc aacaacgcct
     4861 cggtgatcct gcggaagcac gaggcctgac accatggctt tggagaaccg ccgccgcgtc
     4921 gtgatcaccg gggccgggtg cctctcctgc ctcgcggact ctccaggcgg actgcacgcc
     4981 gccctcgtcg caggacatag tgggctcaaa gccatcgagc ttttttccac cgatgcgatc
     5041 ggctgtcatc aggctggcga aatccggccc ttcgacgccc aagcttatct tccggatcgc
     5101 aacctgcggc ccatcgaccg cacctcgcgc cttcttctgg tggcggcggg caaggcactc
     5161 gccgccagcg gccggcccct ggaggtagcc gagcgtgacg acggggaaat cgggctggtg
     5221 ctcggcacca ccttctgcag cttgcgcacg atcgccgagt tcgatcgccg caacctgcag
     5281 cttgggccgt cctacgccag tccgctcgac ttcgccaaca gcgtcatcaa tgccgccgcc
     5341 ggtcaggcgg ccatctggtt cggtctgcgc ggcctcaact ccacgatctc tgccggcgcg
     5401 gcttccgggc tggcggccgt tggctacgcc acggaccaga tccgcggcgg ccgggcaaac
     5461 gcgctgctgg ccggcggcgc cgaggagctg tgcttcgagt cgtttttcgg ccactaccag
     5521 gccggacggc tctgcggctc ggccggcaat cggaatgaag agaagggcga ggtgccaatc
     5581 cccttcgatg ctcgccgcaa cggcttcgcc ctcgccgagg gcgccgcgct gatgatgctc
     5641 gaagacgccg ccgcagcagc cgagcgcggc gccccggtgc tcgccgaggt gctgggccac
     5701 ggctcggggt tcgatccgct cggcacgccg gagagcgccg cgcgcgccgt cgcccgtgcc
     5761 attcgcctcg ccttggagga agccgggctc gggcccttgg acgtcgacgc gttgagcgcc
     5821 ggcgccaacg gcagcgtcga cgccgaccgt tgggaagcgg cgggcgttgc cgcggccctc
     5881 ggagcgcgcg ccgagatatt gcccgtcacc gccgtcaagt cgatgctcgg cgaggccttg
     5941 ggcgcctcgg gcggcctcca gctcgtggct ctgctcggca ctctggaaga cggcgtgctg
     6001 cccggcatcc tgggcctgga gcaaaccgag gagggatttc cgtttcccgg cgcatcgcca
     6061 aacgcgcggc gattgcccgg gcaccgaggg tcgggcgcgg tcaccgcctt ggccacaacg
     6121 ctcagtgcgg acgggcacgc ctgggccgtc ttgctgggca gttggagagg gagcgcgtga
     6181 gcagcgagcc ggtgcctttt cgagcgagtg gcgccggcga cctcgtccct cgcttcgagg
     6241 atcaggggca ctccgccgag gcggtcgcgg cgcggcgcgc ctgggtggag gagcggacgg
     6301 gagcgcggct ggagcaggtc ggcgccgctt cgattcctgc cgaggcctgg cgcggcaacg
     6361 tcgaaaatcc cgtgggcgcc gtacaggtgc cgctgggggt ggccggtccg ctgagggtgg
     6421 agggggagca cgcacgggga gtgttctacg tccccctggc caccaccgaa ggcgccttgg
     6481 tgcgttcgta cgaacggggc atgatgaccc tcacccgcgc cggcggcgcc acggtgcgca
     6541 tgctggccga cgagaatcga gtatcgcccg ttttcgtctt cgacggcgtc gccgaagcag
     6601 ctgccttcgc ccgcgagctg ccggagctgt tcggcgcgct gaagagagag gccgagtcca
     6661 ccactcgcca cggccggctg ttgcgggtgg agccgctggc cctgggccgc gaggtggcgg
     6721 tccacttcgt ctactggacg gcggacgccc atggcatgaa catgatcgtc aaggcgaccg
     6781 accacgcttg ccgctggctg gtggcgcagg ggcacgctgg tcggtattac ttgttcagcg
     6841 gcgccgagtc cgagaagcgg gccagcggct cgctgttcgc cggcggcaag gggaagaagg
     6901 tgacggccgg cgcccgtatc tcgccgcggc tgatgcgggc ctatctgcac acgacgccgg
     6961 cggcgatggc cgacctctgg cagcgcacgg tgctgggcca tctccaggcc ggcgccctgg
     7021 gctacaacgg ccacatcgcc aacggcctcg ccgccctgtt catcgcctgc ggccaggacg
     7081 tggccaacgt cgccaactcg gcggtcggga tcacctcctt tgaggtgctg cccggcggcg
     7141 atctctacgc cagcgtcacc ctgccgtcgc tcaccgtcgc cacggtcggc ggcggcacgg
     7201 gcctcggcac cgcccgcgag tgcctcgaga tgctggggtg cgccggcgag gggggagccc
     7261 cgaagctggc ggagatcacg gccgccatgg cgctcgccgg cgagctgtcg atgggcgctg
     7321 ccgttgccag cggcgagttt gtcgccgcgc acgaaaccta tggccggaat cggccggacg
     7381 aggatgattc tggatgaagc gattgttccg cggcctgcgc cggccgccca atccgtccta
     7441 cgatgccgtt gtcatcggct ccggcatcgg cggattgatc accgccaacc tgttggcgaa
     7501 ggacgggctc aaggtgctgc tggttgagca gcattacatg gtgggcggtt attgcagcac
     7561 ctttcgccgc ggcggctaca ccttcgacgc cgccacccat ttctatccgc tgctgggcaa
     7621 tcccgaaacg ctgaccggcc gcctgctcgt cgagctgggc accgccaccc gctgggtgaa
     7681 gatggacccg gtggacactt tccactttcc ggacggcacg cgcttcgccg tgccggcgga
     7741 cttcgagctc tatcttgccc ggctcaaggc cgaatttccc cacgaggttc gcgctctcga
     7801 caagttcttc gcggcggtgc gcgaagtcta tctgccgggg ctggtgcact acttccacgg
     7861 ccggcccgcc gagcagctgc cgcgtctcgc ccagtaccgc gagctgacag tgaaggatgc
     7921 cctcgaccgc tggttccacg atcccaagct caagctcctg ctcaccgccg actgcccgca
     7981 ctggggctcg cggccggggc gcacgtcgtt cgtcttcgac tcgatgctgc gcctctctta
     8041 cttcctcggc aactactatc cgcagggagg ctcgcaggct ttcgccgacg atcttgcccg
     8101 ctgcttcgag cagcggggcg gccacattct caccagcacc ctcgccaggc gcatcgtcgt
     8161 cgaggaaggc gaggctcggg gtgtcgagct cgaggtcctg cgcggccacg tgctgccgca
     8221 atggcgaagc ggcgtggtga aaagcggcgt ggtgatctcc aacgccgacc tgctgctgac
     8281 cctggagcgg ctggtgggac ccaggcacct gccgccggac gccgtcgagc ctctccgccg
     8341 cctgcggacg acctttccct gctggctcac ccacctgggt ctcaagggcg tgccggcgaa
     8401 cgttctggcg gaggctcagg gctaccactg gcgttcgtgg gacatggagc gggtggggcg
     8461 ggacgccctc tgcttcaagc tctttgctcc cacactcttt gagccctcgc tggcgcctgg
     8521 aagcgagcag atcctcatcg ttcaaaaggt ccaggaattg gactacgacg ccgtcgatga
     8581 ctggccgcgc cacaagcgcg aggtcgaggc tttcgtcttt gcgaacctgg aacgggtgat
     8641 ccctggaatc ggcgcgcaaa tcgccgtgcg gagcagcgct tcggcctaca cctcagggcg
     8701 gtttactctt aattcgcggg gagcgatgct cggctgggag atgtcgcccg agcagttggg
     8761 cgccggccgg cccagacctg agacggcgat tcgcaatctc cattgcgtgg gacactggac
     8821 ccaacccgga ggcggcgtca cgccggtaat cgtttccgcc cagcgcgtgg cgcagaccgt
     8881 gcttcgcggt gccgcaggca gcgagtcacc aggcctaccg atcagaatgg cggcggccgg
     8941 aatccgctaa ggagggcagt catggcatgc tccttcgaag acagcggcgt ggcgatcttt
     9001 cggcctcgac tcattcccgg tggggcgatg cctgacctcg ccgcagccgc ggatgacctc
     9061 gcggcctgtg ctcgcagcca gccagcccgt ctcgttctgc tatcgtctgc cgccgcgctc
     9121 gatccgagcc atcacaaccc tggctttgtg gccgagacct accggcctga ggggacgaat
     9181 cccatcgccc gggcctggag ggagctcgaa gccctggcgg cggcgaagtt gccgcaggcc
     9241 gagcggatcg tcctccggcc cgctcccgtc gccgctcgca aggacgctga cttcatctcc
     9301 cgccggctcg ccggtgcctc tgccgtggtg ccgccggggt tcgacccggc cttgcaattc
     9361 ttggcgccag cggatcttga ggccgccgtg tgttgcgccg tggagcgggg agcgggccgg
     9421 ccggggcttt tccacgtcgc gccgcggggc gccgtgcccc tgcgcacggc catgcgactg
     9481 gcgggcgtgc ggtgcctgcc tctggcatgg accggcgccg gcggcgagaa cgattacctg
     9541 cgccacaact ggaccgtctc gggcgctaaa atcgagcgtg agcttggatt cgtccccaaa
     9601 accacgagcg cggcggcggt gcttgcggcg ttcgcgaccg ccggctctgc cgttccgcag
     9661 cccgacgact tcgggctcga ccttggttac atcgccgcct atgagcggac gctcttccgc
     9721 ttcctgcacg acctctactg gcggatcgag gttgtaggca ccgagaacct gccgcgggag
     9781 ggtggggcgg tgctgaccgg cgtccaccgc ggctttatgc cctgggacgg cgtgatggcg
     9841 ctggtggccg tacaccgcgc cgtgggacgg gtaccgcgct tcctcatcca cccgtgtctc
     9901 atcaagccgc ccttcctcgc caactatatg atcaagctgg gcggcatcgt cgccaaccag
     9961 gagaacgcgg attgggtgct ctcgcgaggc gatctgttgg gcatgttccc cgagggcatc
    10021 cacggtgcct tcaccatgta ccgggacgcc tacaagctgg gtaagttcgg gcgcgacgag
    10081 tacgtgaaga tggcgctgcg caaccgcgtg cccctcgtcc ccttcgtcac cgtgggcagc
    10141 gccgagatct atcccatctg gggccggctc gactggaaat gggtcaagcg ggcgaccgag
    10201 tggctttttc tgccgttggg acccaatttt ccgtttcccg gcctgccgct gccctcgaaa
    10261 tggcacacgc ggtttctggc gccgatcccc gtccaggagc agtatggtcc cgaggccgcg
    10321 gacgatccgg cagtggtaaa ggccatcagc gccgaggtgc gggcgcgcat gcaagcggcg
    10381 atcgacgaga tgctggcgcg gcgcaagtca atcttctggg gcacgatttt cgatcgcatc
    10441 gagactgagc caggatcctt ggatgtcgtt cgacccggta gccttccgcg agttggcggg
    10501 taagttgcgc gccttcgccc tgtttcgcgg cgccgggatg gcgccggaga gagcgctcgc
    10561 tcgcgccgcg cggctgaatc cctggtcgcg cctcttcgtg ctcgaaggca tcggctacgc
    10621 acgagggaac gccggctggc cgcctcaaag ctcggaagat ggcgcgctga ttcccctcac
    10681 catgggctgg gggctggcgc tggcggtgcg ctcgttccgg tctgcgcgcg cgaggattac
    10741 gcctgaagag tcattgcgga gctttgccgc cgcttgccgc gagctcgcgc cgccaggcct
    10801 taccggtgtg gctttcgagg gattgggctt ggtggcccgg ctgcaatggg ccaaggcggt
    10861 gccggctctc tcgcgagccc tgggtgaaat ggacggcggt ctcgaggctc ggttctggca
    10921 cggtgtgggg cggggccttt tctttctgcc cggcgatact tttctctggg gcagctccgc
    10981 aggtcgggcc ttggcgagag cgctgcacga accgccggcc ggtcttcccc gggccaacac
    11041 cctggccggc ctggccatgg ccatcaccct catctgccta ccgcatccca gagtgatcga
    11101 tcgattcctg agccgtcact ccggacaaat tgacgacgcg gcttcgttcc agtacggaat
    11161 cgccgcggca gccctggtct ggtgccgtgc ggcaggccgg gacgagcttt tgcagcgtct
    11221 cctgtcccat ccttcccaga caccagaaca ctggcaggcg tgggttcggc ggccctgcga
    11281 gcaggcgctc ggcgagagct tcccggtttt ggttcgcgat ggcggctggg acgatctttt
    11341 tcgggtgatg cgatgaagcg gcgccggttc ctcatcttcg gcctgctcgc tgtggtgatc
    11401 tttttgtccg gcggttggct gaccctggac cgcctggacc gccgggggag agagttttac
    11461 gaagccggcc gcgccgtggt tgcggcgctc gacttgctgg ccggcgatct ctcccgccgg
    11521 gatctcgccg ctgtcggcaa tgtctactcg cctgatttcc acggctcctc tctgggcctc
    11581 gcgagctttc aacctgcggc ggagaaggac ggcatcgcaa ccttgcgact gataccaggc
    11641 aaggggaaag cggatcgtgg ctcggccgtc gccgaatggc gcgcctacct cgacggcttc
    11701 cagtcgatcg aggagctcgg cctccacctg caccgcgtcg aggcttggga agcgggaggc
    11761 gaggtgacgg ccatggtgcg attcgaggtc atcggcacgc tgaaaggcca tgctcggtcg
    11821 ggcatcgacc gcgcgctctt ccgcatgtgt ttcgtgccgg gcggaaatgg attgcagatc
    11881 gctgaggcat cgcccgttga aggcgagcgg ctggaggctg accggccgca gttcgaagag
    11941 gtgggccacg cggcgggcat cgatttccag aaccgttact atcctccatt cctcactacg
    12001 ccgctgcgct tcggcatgat ccgctacggc cccggcggca tcagcgccgt ggacttcgac
    12061 aacgacggcc tctacgattt gttcattccc gacggcgtcg aatcgcgcct gtttcacaac
    12121 cgcggcgacg gcaccttcga ggacgtgaca gcggcttccg gcctcgccgg cctcgacggc
    12181 gtttccgtgg gagtcttcgc cgactatgac aacgacggct ggaaagatct cttcgtcagc
    12241 cgcaccttca agcccaacca gcttttccac aacgatggac cggacgcctc cggccacatc
    12301 catttcaccg acgtcaccgc caagtcacgc ctcggcgagg attgctgcac caccgtcgcc
    12361 tcctgggggg attacgacaa cgacggtcgc ctcgatctct acgtggggcg ctatctcgat
    12421 ccacgaaaga agatccccac cactttctat gctcgaaacg gcgagggcaa ccggctctat
    12481 cacaacaacg gcgacggcac cttcaccgac gtcaccgccg ccgcgggcgt tggcgacacc
    12541 gggctctgcc tgggcagcgt ctggggcgac tataacgacg atggccgccc cgatctctac
    12601 gtggtcaacg acttcggccg taagaccctg taccgcaaca acggcgacgg tactttcacc
    12661 gacgtgacgg tggcgagcgg caccctcgac tacggcgccg gcatgagcgc ctctttcggc
    12721 gactacgaca acgacggcaa gctcgacctc tacgtcgcca acatccgctc cgagcactcc
    12781 tggctcgccg aatcccctac cgtctggcgc tacatggcca actcctggcg gcagggcgta
    12841 tggcggaccg acatgcccct ctatttccag attttccgcc agtcggggag ccggttcgtt
    12901 caggttttcc agcagatggc gtcgggcaac acactgctgc gcaacaaagg cgacggcacg
    12961 ttcgaggacg tcacctggaa ggcggacgcc aaccccgtcg gctggttctg gggctcgggg
    13021 ttcggcgact tcgacaacga cggtttcctg gacgtctaca gcgccgacgg ctgggtttac
    13081 aacgacaagg ggaccgagct cgagctcgac ttcctcaaca acgtcgtcgg caaccaggcg
    13141 gagtacaaga agggcacctt cttcgatccc aagcaattcg gcaggctctc gtggcacggc
    13201 tgggagcgca atcgccatct gctgaaccga ggcgacggta ccttccagga gatcggccgg
    13261 ccggccggca gcgacttgat cctcaacagc cgcggcgtcg ctctcgccga tctctggaac
    13321 cgcggcgtgc tcgacatcgc cgtcgccgcc agcgccgacc ggcacgccct gctgcgcaac
    13381 gaggtgggac aagcgggaca gaggcggcac tggctggaga tcgagctgcg aggcgtgaag
    13441 tccaaccgtg acgccgtagg cgcccgcgcc gtcgtgcgcg ccggcggcaa gacgctcact
    13501 cgcgaggtgg tggccggcga cggttacgcc tcgcagaaca tgctgcgcct ccatttcggt
    13561 ctcggcgagc ccggcacggt ggacgagctg acggtaagat ggccggcatc cgggaccgtc
    13621 cagcgcttcc ggaacgtccc cgcggaccgc atcgtccagt tgaccgaagg tggaagtctg
    13681 caacctttcc
//
