LOCUS       c00216_3300012..        4531 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300012533.a:Ga0138256_10044039.
ACCESSION   c00216_3300012..
VERSION     c00216_3300012..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 10:15:12
            Original ID  :: 3300012533.a:Ga0138256_10044039
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 4531
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..4531
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2:2513](-)"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(3..2513)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
     cand_cluster    1..4531
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /kind="single"
                     /product="NRPS-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..4531
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS-like"
                     /region_number="1"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX))"
                     /tool="antismash"
     CDS             complement(3..2513)
                     /NRPS_PKS="Domain: NAD_binding_4 (28-373). E-value:
                     7.3e-51. Score: 164.4. Matches aSDomain:
                     nrpspksdomains_ctg216_1_NAD_binding_4.1"
                     /NRPS_PKS="Domain: AMP-binding (580-831). E-value: 1e-54.
                     Score: 177.4. Matches aSDomain:
                     nrpspksdomains_ctg216_1_AMP-binding.1"
                     /NRPS_PKS="type: NRPS-like protein"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: NAD_binding_4"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     186.8; E-value: 9e-57)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg216_1"
                     /sec_met_domain="AMP-binding (E-value: 2.2e-54, bitscore:
                     171.6, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_binding_4 (E-value: 2.9e-52, bitscore:
                     164.4, seeds: 102, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSETDTNGEANVTPLLPSRILAGKRLVVVGGTGFLGKVWVSMLLH
                     RFPDIGHLYLFVRPKAGQTAEERFWSQIASSTCFDPLREVHPGAEFEKWIAQKITACAG
                     DVVMPECGLDKDLLARIDGTIDAVVNVAGVVDFNPPLDEALEVNAFGVTNLVSLAKRLR
                     APMMHTSTCYVAGYREGLIEEVDPREVPFPRAQGETWFGAGIEKRTLDRSHWDPQREID
                     ECLDLIKQARHRGCDAFRQSAFLDQAKANLQARQEPCRGNALEDELVKVKRRFIERQLI
                     DAGTERAHFWGWTNIYTYTKSIGEQVLAASGVPFTIVRPAVIESSSTYPVPGWNEGVNT
                     SAPFIYMAIAGQVQLPGDPRVHLDIIPCDMVTSGMIAALCELIEGKAAPVYQFGTTDTN
                     GCKVTRYYELIGLYKRRLVREGKKSALFDHIKAHFEAIGLTKNQYHSRGAHAIANAMRT
                     ASGIVGKVAAGPVRPLLKPVSEALENAARTEDKIGDVMDLFLPFTAEGDWIFSCANTRA
                     AMARMPPEERNKFFWEPEKLDWRQWMWEIHIPGLEKWVFPLIDEKQRKELKALRKYDTL
                     VDMVEEAAERHDHAVALQLLTDEGFTRTTYRELRDGMLQTAARLAAIGVRPGDAVILSG
                     DNHPSWPVAYFGILRAGAIAVPIDPALDERQIGNIVRSSGAKVALWDATVESKGGRAAR
                     ALHPEMAVYDITTFADPDAPASLTPPDIQVKSTDIASIIYTSGTTGDPKGVMLSHDNFT
                     ALVAALGPIFPLTGHDRLLSVLPIHHTFEFTCGLLLPLSRGTRIIYVGELSGDRVSKGL
                     QQGRITAMVGVPALWQLLERRIVAK"
     aSDomain        complement(21..773)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg216_1_AMP-binding.1"
                     /evalue="1.00E-54"
                     /label="ctg216_1_AMP-binding.1"
                     /locus_tag="ctg216_1"
                     /protein_end="831"
                     /protein_start="580"
                     /score="177.4"
                     /specificity="consensus: X"
                     /tool="antismash"
                     /translation="EEAAERHDHAVALQLLTDEGFTRTTYRELRDGMLQTAARLAAIGV
                     RPGDAVILSGDNHPSWPVAYFGILRAGAIAVPIDPALDERQIGNIVRSSGAKVALWDAT
                     VESKGGRAARALHPEMAVYDITTFADPDAPASLTPPDIQVKSTDIASIIYTSGTTGDPK
                     GVMLSHDNFTALVAALGPIFPLTGHDRLLSVLPIHHTFEFTCGLLLPLSRGTRIIYVGE
                     LSGDRVSKGLQQGRITAMVGVPALWQLLER"
     aSModule        21..773
                     /domains="nrpspksdomains_ctg216_1_AMP-binding.1"
                     /incomplete
                     /locus_tags="ctg216_1"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(267..326)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg216_1_0002"
                     /evalue="5.10E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg216_1"
                     /protein_end="749"
                     /protein_start="729"
                     /score="28.2"
                     /tool="antismash"
                     /translation="ASIIYTSGTTGDPKGVMLSHD"
     CDS_motif       complement(537..578)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg216_1_0001"
                     /evalue="1.90E-03"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg216_1"
                     /protein_end="659"
                     /protein_start="645"
                     /score="11.8"
                     /tool="antismash"
                     /translation="FGILRAGAIAVPIDP"
     aSDomain        complement(1395..2429)
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg216_1_NAD_binding_4.1"
                     /evalue="7.30E-51"
                     /label="ctg216_1_NAD_binding_4.1"
                     /locus_tag="ctg216_1"
                     /protein_end="373"
                     /protein_start="28"
                     /score="164.4"
                     /tool="antismash"
                     /translation="VGGTGFLGKVWVSMLLHRFPDIGHLYLFVRPKAGQTAEERFWSQI
                     ASSTCFDPLREVHPGAEFEKWIAQKITACAGDVVMPECGLDKDLLARIDGTIDAVVNVA
                     GVVDFNPPLDEALEVNAFGVTNLVSLAKRLRAPMMHTSTCYVAGYREGLIEEVDPREVP
                     FPRAQGETWFGAGIEKRTLDRSHWDPQREIDECLDLIKQARHRGCDAFRQSAFLDQAKA
                     NLQARQEPCRGNALEDELVKVKRRFIERQLIDAGTERAHFWGWTNIYTYTKSIGEQVLA
                     ASGVPFTIVRPAVIESSSTYPVPGWNEGVNTSAPFIYMAIAGQVQLPGDPRVHLDIIPC
                     DMVTSG"
     CDS             complement(2969..4531)
                     /locus_tag="ctg216_2"
                     /transl_table=11
                     /translation="DPDVAERPQDLVVYGGTGKAARSWEAFDVIVRELQLLEEDETLLV
                     QSGKAVGRVRTHPDAPRVLIANSNLVGRFATWEDFRRLEQLGLIMYGQMTAGSWIYIGT
                     QGILQGTYETFVAARNAHVARTGRAGARWVLTAGLGGMGGAQPLAATMAGMSCLAVEVD
                     STRIDRRLATRYVDRRIDDLDEALRVIEASIERAAPVSIALCANAADVFPELVRRGVVP
                     DLVTEQTAAHDPLKGYIPQGLSLNAAVALREKNAKEYVVRAKQSMRIEVEAMLEMAQCG
                     AEVFDYGNNIRTCAMEAGCERAFDVPGFVPAYIRELFCQGKGPFRWVALSGDPEDILET
                     DRAVLEAVPNDPDLARWIRLAEERVSFQGLPARICWLGLGDRAKVGLAFNELVRTGKVK
                     APIVIGRDHLDCGSVASPFRETEAMKDGSDAIADWAILNALANTAGGASWVSFHHGGGV
                     GIGNSLHAGMVVVADGTDAAAKRLERVLTIDPTMGVIRHADAGYETAIRVADEKGVRVP
                     HRA"
ORIGIN
        1 accttggcaa cgatacgccg ttcgagcaac tgccaaagcg cggggacgcc caccattgcg
       61 gtgatgcggc cctgctgcag tcccttggat acccggtcgc cgctcaattc cccgacataa
      121 ataatgcgag ttccacgtga tagtggcaga agaaggccgc acgtgaattc gaaggtatgg
      181 tgaatcggca ggacactcag cagtcgatcg tgcccagtga gcgggaaaat gggtccgagc
      241 gctgctacga gagctgtgaa gttgtcatga gagagcatga cgcccttcgg gtcgcccgtc
      301 gtgccactcg tgtaaatgat gctggcgatg tcagtgcttt tgacttgaat gtccggcggc
      361 gtcagtgaag cgggtgcatc gggatctgca aacgttgtta tgtcgtacac cgccatttcc
      421 ggatgcaatg cgcgcgccgc tcggccgcct ttcgattcca ctgtggcgtc ccagagcgcc
      481 actttcgcgc ctgacgaacg cacgatattg ccaatttgac gttcgtcgag tgcaggatcg
      541 attggcactg caatggcccc agctcgcaaa atgccaaaat atgccactgg ccacgaaggg
      601 tgattgtcgc cggatagaat gactgcatcg ccaggacgaa caccgatggc agcgaggcgt
      661 gcagccgttt ggagcattcc atcacgaagc tcgcgatacg tcgtgcgggt aaatccctcg
      721 tccgtgagaa gttgcaatgc cacggcgtga tcgtgacgct cggcggcttc ttccaccatg
      781 tcgacgaggg tgtcgtattt gcgcagagcc ttgagttctt tgcgttgttt ttcatcgatg
      841 agcgggaaaa cccacttttc caggcccgga atgtggattt cccacatcca ctgtcgccaa
      901 tcgagctttt cgggctccca gaaaaacttg ttacgctcct cgggcggcat acgtgccatg
      961 gccgcgcgtg tgttcgcgca agaaaagatc caatcgcctt cggccgtgaa gggcaagaag
     1021 agatccatca cgtcgccgat tttgtcttcg gtacgcgctg cattttcgag cgcttccgaa
     1081 acgggtttca agagaggtct cacgggcccg gcggccactt tcccaacgat tccactggcc
     1141 gtgcgcatcg cgtttgcgat cgcgtgcgcg cctcgtgaat gatattgatt cttggtcaac
     1201 ccaatggctt cgaagtgcgc cttgatgtga tcgaaaagtg cgctcttttt accttcccgc
     1261 acgagccgac gcttgtaaag gccaatcagc tcgtaatagc gcgtcacttt gcacccattc
     1321 gtgtcggtcg tgccgaattg atatacgggt gcagccttgc cctcgatcaa ttcgcagagc
     1381 gcagcgatca tgccgctcgt aaccatatca caaggaatga tatcgagatg cactcgggga
     1441 tcgcccggca attgcacctg gcccgcaatt gccatgtaga tgaacggggc gctcgtattg
     1501 accccttcat tccatcccgg caccggatac gtactcgacg attcaatgac ggccggccgt
     1561 acgatcgtaa aaggtacgcc gctcgccgca agcacctgtt cgccaatgct ttttgtgtag
     1621 gtgtagatgt tggtccagcc ccagaaatgc gcacgctcgg tgcccgcatc gatcagttgc
     1681 cgttcgatga agcgacgttt taccttgaca agctcgtcct cgagcgcgtt gccgcgacac
     1741 ggttcctgac gggcctgaag gtttgccttg gcttgatcga gaaacgcgct ttgacggaat
     1801 gcatcgcagc cacggtggcg ggcctgtttg atgaggtcga gacactcgtc gatttcgcgt
     1861 tgcggatccc aatgcgaacg atcgagcgtt cgcttctcga tgcccgcacc gaaccacgtt
     1921 tcgccctgcg cgcgtggaaa tggcacttca cgcggatcga cttcttcgat gagcccctcg
     1981 cgataccccg caacgtaaca cgtgctcgtg tgcatcatcg gcgcgcgcaa tcgtttggcc
     2041 aatgaaacga ggttcgtcac accaaacgcg ttgacttcga gcgcttcgtc gagcggcggg
     2101 ttgaagtcga cgacgccagc gacgttgacg acggcgtcga tggtgccgtc gatgcgtgca
     2161 agcaggtctt tgtcgagacc gcactcgggc atgacgacgt cgccggcgca agcggtgatt
     2221 ttttgagcga tccacttttc gaactcggca ccggggtgca cttcgcggag cggatcgaag
     2281 caagttgacg aagcaatttg ggaccagaag cgttcttcgg cggtttgtcc ggccttgggt
     2341 cttacgaaca agtacaagtg gcctatgtcg ggaaagcgat gcaagagcat cgatacccag
     2401 accttgccga gaaagccggt acctccgacg accaccaacc gtttgcccgc gaggatgcgc
     2461 gaagggagca gcggggtgac gttggcttct ccgttcgtgt ccgtctcgct catgtgaaat
     2521 cgcctcgttt gccgcgtgaa aaggccgcta ataacgcgcc ttgtgctgcg cgcaccacgt
     2581 gcatgcagtg ctcggcggcg agtggatttc cggtgcttcg ccgatcaagt caaggccaaa
     2641 gccaacgcga acgcagatac gcacgaatcg cgagcggatt tgaagatgcc gcgcgttgcg
     2701 acggcgagtg gacgaccgtc gctgttcgca gatcgttgca cgacaaaaga agcgctatcc
     2761 gcgcatgtaa cgaggggatt gacaagcctc atgagacatg cgtccgcagc gcccctgttg
     2821 tgaacacaag cttgcgtcgt caattggttg gacgtcaaac gaaatgtacg ggacgcacgt
     2881 tgtttggtag tcaaaggaaa tcgcacgact tgccagctcg aaggattgtc tggcacggtg
     2941 cttctcggcg acaaacacca gggtccactc acgcccggtg cggcaccctc acgcccttct
     3001 cgtcggccac tcgaatcgcc gtctcatacc ccgcatccgc atgccgaatg acgcccatcg
     3061 tcgggtcgat cgtgagcact cgttcgagcc gcttcgctgc cgcgtccgtt ccatcggcca
     3121 cgacgaccat gcccgcgtgc agcgaattgc caatccccac gccgcctccg tgatgaaaac
     3181 tcacccacga tgcgccaccg gcagtattcg caagcgcatt caggatggcc caatccgcaa
     3241 tcgcatccga tccgtccttc atggcttcgg tttcgcggaa aggcgacgcg acagagccac
     3301 aatcgagatg atcacgccca atgacgatgg gcgccttgac tttgccggtt cgcacgagct
     3361 cattgaaggc caaacccacc ttggcgcgat cccccaaacc gagccagcag atgcgcgcgg
     3421 gcaatccttg aaatgaaacg cgctcctcgg ccaatcgaat ccaccgcgca aggtccggat
     3481 cattcggaac cgcctcgaga acggctcgat ccgtttccaa aatatcttcc ggatcacccg
     3541 acagagccac ccaccgaaac ggccccttgc cctggcaaaa caattcacgg atatatgccg
     3601 gaacaaaccc cggaacgtcg aacgctcgct cgcaacccgc ttccatggca cacgtgcgaa
     3661 tgttgttccc gtaatcgaat acctcggctc cgcattgcgc catctcgagc atcgcctcga
     3721 cttcgatacg catcgactgt ttggcacgta caacatattc tttcgcgttt ttttcacgca
     3781 atgcgacggc cgcgttcagc gatagtccct gcggaatgta acctttcaat ggatcgtgcg
     3841 ccgccgtttg ctcggtgacg agatcaggca ccacaccacg ccgtacgagc tcggggaaaa
     3901 catccgcggc attggcacat aacgcaatcg acaccggcgc cgctctctcg atcgacgctt
     3961 caatgacccg aagcgcttcg tcgagatcgt cgatacgccg atcaacgtaa cgagtcgcaa
     4021 gccttcgatc aatgcgcgtc gaatcgactt cgaccgccaa acacgacatg cccgccatcg
     4081 tcgccgcaag cggctgcgcc ccgcccattc cgccaagtcc cgcagtcaaa acccaacgcg
     4141 cccccgcgcg ccccgtacgc gccacatgag cgttacgtgc cgcgacaaac gtctcgtacg
     4201 taccctgcaa aatcccctgc gtgccaatgt aaatccacga ccccgccgtc atctgcccgt
     4261 acatgatgag cccgagttgt tcgagtcggc gaaagtcctc ccacgtcgca aaacgaccca
     4321 ccaggttcga attggcaatc aaaacccgcg gtgcgtccgg atgtgttcga acgcgaccca
     4381 ccgctttgcc agactgcacg agcaacgtct cgtcttcctc gagcagttgc agctcgcgca
     4441 cgatgacatc gaacgcttcc cacgaacgag ccgcttttcc cgtaccgccg tacaccacga
     4501 ggtcttgcgg acgctcggcg acgtctggat c
//
