LOCUS c00245_3300012.. 3546 bp DNA linear UNK 01-JAN-1980 DEFINITION 3300012805.a:Ga0160464_102372. ACCESSION c00245_3300012.. VERSION c00245_3300012.. KEYWORDS . SOURCE ORGANISM . COMMENT ##antiSMASH-Data-START## Version :: 5.1.0 Run date :: 2019-11-23 06:59:42 Original ID :: 3300012805.a:Ga0160464_102372 NOTE: This is a single cluster extracted from a larger record! Orig. start :: 0 Orig. end :: 3546 ##antiSMASH-Data-END## FEATURES Location/Qualifiers CDS complement(1..474) /NRPS_PKS="Domain: Condensation_LCL (46-157). E-value: 5.5e-27. Score: 86.3. Matches aSDomain: nrpspksdomains_ctg245_1_Condensation_LCL.1" /NRPS_PKS="type: NRPS-like protein" /gene_functions="biosynthetic (rule-based-clusters) NRPS: Condensation" /gene_kind="biosynthetic" /locus_tag="ctg245_1" /sec_met_domain="Condensation (E-value: 7.9e-22, bitscore: 64.7, seeds: 42, tool: rule-based-clusters)" /transl_table=11 /translation="MQAAKDGGHNQNQNRWSATKQMLLAALLEEVNAGQSELMRGALTP QAPLPLSFAQDRMWFVHTLDPDSPVNHMPASIAFRGQLDAEALERSVQTIVGRHEALRT VIRETADGEREQLVLADGRAAWSSEDLRHWPPAERELEVKRQAAAVSREPFLLE" protocluster 1..3546 /aStool="rule-based-clusters" /contig_edge="True" /core_location="[0:3546]" /cutoff="20000" /detection_rule="(cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))" /neighbourhood="20000" /product="NRPS" /protocluster_number="1" /tool="antismash" proto_core 1..3546 /aStool="rule-based-clusters" /tool="antismash" /cutoff="20000" /detection_rule="(cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))" /neighbourhood="20000" /product="NRPS" /protocluster_number="1" cand_cluster 1..3546 /SMILES="NC(CO)C(=O)O" /candidate_cluster_number="1" /contig_edge="True" /detection_rules="(cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))" /kind="single" /product="NRPS" /protoclusters="1" /tool="antismash" region 1..3546 /candidate_cluster_numbers="1" /contig_edge="True" /product="NRPS" /region_number="1" /rules="(cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))" /tool="antismash" aSDomain complement(4..336) /aSDomain="Condensation" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg245_1_Condensation_LCL.1" /domain_subtype="Condensation_LCL" /evalue="5.50E-27" /label="ctg245_1_Condensation_LCL.1" /locus_tag="ctg245_1" /protein_end="157" /protein_start="46" /score="86.3" /tool="antismash" /translation="APLPLSFAQDRMWFVHTLDPDSPVNHMPASIAFRGQLDAEALERS VQTIVGRHEALRTVIRETADGEREQLVLADGRAAWSSEDLRHWPPAERELEVKRQAAAV SREPFLLE" aSModule 4..336 /domains="nrpspksdomains_ctg245_1_Condensation_LCL.1" /incomplete /locus_tags="ctg245_1" /tool="antismash" /type="nrps" CDS_motif complement(154..267) /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg245_1_0002" /evalue="1.60E-16" /label="C2_LCL_024-062" /locus_tag="ctg245_1" /protein_end="107" /protein_start="69" /score="52.6" /tool="antismash" /translation="VNHMPASIAFRGQLDAEALERSVQTIVGRHEALRTVIRE" CDS_motif complement(289..321) /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg245_1_0001" /evalue="4.30E-04" /label="C1_LCL_004-017" /locus_tag="ctg245_1" /protein_end="62" /protein_start="51" /score="12.5" /tool="antismash" /translation="SFAQDRMWFVHT" CDS complement(475..3546) /NRPS_PKS="Domain: Condensation_LCL (5-231). E-value: 1.3e-75. Score: 246.0. Matches aSDomain: nrpspksdomains_ctg245_2_Condensation_LCL.1" /NRPS_PKS="Domain: AMP-binding (395-800). E-value: 4.5e-112. Score: 366.3. Matches aSDomain: nrpspksdomains_ctg245_2_AMP-binding.1" /NRPS_PKS="Domain: PCP (915-983). E-value: 2.6e-20. Score: 64.2. Matches aSDomain: nrpspksdomains_ctg245_2_PCP.1" /NRPS_PKS="type: NRPS" /gene_functions="biosynthetic (rule-based-clusters) NRPS: AMP-binding" /gene_functions="biosynthetic (rule-based-clusters) NRPS: Condensation" /gene_functions="biosynthetic-additional (rule-based-clusters) PP-binding" /gene_functions="biosynthetic-additional (smcogs) SMCOG1127:condensation domain-containing protein (Score: 361.1; E-value: 1.6e-109)" /gene_kind="biosynthetic" /locus_tag="ctg245_2" /sec_met_domain="Condensation (E-value: 1e-55, bitscore: 175.9, seeds: 42, tool: rule-based-clusters)" /sec_met_domain="AMP-binding (E-value: 1.6e-124, bitscore: 402.7, seeds: 400, tool: rule-based-clusters)" /sec_met_domain="PP-binding (E-value: 1.4e-16, bitscore: 48.1, seeds: 164, tool: rule-based-clusters)" /transl_table=11 /translation="VLADGRAAWSSEDLRHWPPAERELEVKRQAAAVSREPFLLEEGPL LRARLLRVEPERHMLLVAVHHIVFDGWSMGVFLQELSALYAAYASGETPRLAEPALQYR DFASWQRETLQGERLEQLLDYWSRRLEGAELTLELPTSKPRPPVQRFRGRTWTQRLGRP LIRQLEERGRAEGATLFMVLLAAFNTLLYRYTGQTGIAVGTPIAGRTRVELEEVIGLVM NSLVLYTDLTGEPTFRELVGRVKETAIGAYAHQELPFEKLVDRLQPERDLSRSPLFQVM FVLQNAPMPAQGLPGVEMQVEELDSGTAKYDLTLRATESEQGLVIAWEYDTELFEQEAI ERMAGHYETLLAGIAADPDCRIGELPMLTPGERIQLQTWNATSTALPQVPYVHKQFEAQ AAATPEAEALVFEGETLTYEALNRRANQLASYLLEHAAEHTRFIGVYMDRSLELVVSLL AILKAGKAYVPVDPGNPAKRVEYMLADAELQFVVTDSRSSSRLLEAVPRLQPGMEIVEV DRLEAERYDADNPACALHPQDPVYLIYTSGSTGHPKGAVNTHIGLANRLLWMKHHFAFT PDDCFLQKTPFGFDVSVWEFFAPLISGARLVVAKPEGHKDSRYLQRLIDRHRISVIHFV PSMLHVFLRDAAESETLCPSLRHVFCSGEALSLPLVQLFCAKNTPALLHNLYGPTEAAI DVTSWTCPPTGQEGAVPIGRPVWNTTLHVLDERLQQVPIGVVGELYIGGVQVAKEYYGR PELTRERFIAHPLAGEGVLYRTGDLVRYRPDGQLEYIGREDNQIKLRGFRVELGEIEAA IVTHETIAEAVVTVWDAGDDDRRLVAYVAAQGGHPESVSQIRRHLAERLPEYMIPSIWV MLDRLPLSRNGKVDKRALPDPLSLSGDALLARQADECAALDGPIERVLADIFAEVLKIG TVSPVISFFEQGGNSLLATQVTARIKQWFQFELPLLELFQHPTVRGLAEVLMASEHRDR IAKLAERILELTAMSEAEAAERLKVRSSVGEGVN" aSDomain complement(598..801) /aSDomain="PCP" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg245_2_PCP.1" /evalue="2.60E-20" /label="ctg245_2_PCP.1" /locus_tag="ctg245_2" /protein_end="983" /protein_start="915" /score="64.2" /tool="antismash" /translation="ERVLADIFAEVLKIGTVSPVISFFEQGGNSLLATQVTARIKQWFQ FELPLLELFQHPTVRGLAEVLMAS" aSModule 598..3531 /complete /domains="nrpspksdomains_ctg245_2_Condensation_LCL.1" /domains="nrpspksdomains_ctg245_2_AMP-binding.1" /domains="nrpspksdomains_ctg245_2_PCP.1" /locus_tags="ctg245_2" /monomer_pairings="ser -> ser" /tool="antismash" /type="nrps" CDS_motif complement(1117..1182) /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg245_2_0008" /evalue="2.80E-11" /label="NRPS-A_a8" /locus_tag="ctg245_2" /protein_end="810" /protein_start="788" /score="35.4" /tool="antismash" /translation="YIGREDNQIKLRGFRVELGEIEA" aSDomain complement(1147..2361) /aSDomain="AMP-binding" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg245_2_AMP-binding.1" /evalue="4.50E-112" /label="ctg245_2_AMP-binding.1" /locus_tag="ctg245_2" /protein_end="800" /protein_start="395" /score="366.3" /specificity="consensus: ser" /tool="antismash" /translation="FEAQAAATPEAEALVFEGETLTYEALNRRANQLASYLLEHAAEHT RFIGVYMDRSLELVVSLLAILKAGKAYVPVDPGNPAKRVEYMLADAELQFVVTDSRSSS RLLEAVPRLQPGMEIVEVDRLEAERYDADNPACALHPQDPVYLIYTSGSTGHPKGAVNT HIGLANRLLWMKHHFAFTPDDCFLQKTPFGFDVSVWEFFAPLISGARLVVAKPEGHKDS RYLQRLIDRHRISVIHFVPSMLHVFLRDAAESETLCPSLRHVFCSGEALSLPLVQLFCA KNTPALLHNLYGPTEAAIDVTSWTCPPTGQEGAVPIGRPVWNTTLHVLDERLQQVPIGV VGELYIGGVQVAKEYYGRPELTRERFIAHPLAGEGVLYRTGDLVRYRPDGQLEYIGRED NQIKLRG" CDS_motif complement(1264..1353) /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg245_2_0007" /evalue="4.50E-16" /label="NRPS-A_a6" /locus_tag="ctg245_2" /protein_end="761" /protein_start="731" /score="50.9" /tool="antismash" /translation="PIGVVGELYIGGVQVAKEYYGRPELTRERFI" CDS_motif complement(1870..1926) /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg245_2_0006" /evalue="5.90E-08" /label="NRPS-A_a3" /locus_tag="ctg245_2" /protein_end="559" /protein_start="540" /score="25.0" /tool="antismash" /translation="YLIYTSGSTGHPKGAVNTHI" CDS_motif complement(2134..2175) /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg245_2_0005" /evalue="3.90E-05" /label="NRPS-A_a2" /locus_tag="ctg245_2" /protein_end="471" /protein_start="457" /score="16.8" /tool="antismash" /translation="LAILKAGKAYVPVDP" CDS_motif complement(2695..2814) /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg245_2_0004" /evalue="1.30E-26" /label="C67_LCL_14fromHMM" /locus_tag="ctg245_2" /protein_end="284" /protein_start="244" /score="85.1" /tool="antismash" /translation="KETAIGAYAHQELPFEKLVDRLQPERDLSRSPLFQVMFVLQ" aSDomain complement(2854..3531) /aSDomain="Condensation" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg245_2_Condensation_LCL.1" /domain_subtype="Condensation_LCL" /evalue="1.30E-75" /label="ctg245_2_Condensation_LCL.1" /locus_tag="ctg245_2" /protein_end="231" /protein_start="5" /score="246.0" /tool="antismash" /translation="RAAWSSEDLRHWPPAERELEVKRQAAAVSREPFLLEEGPLLRARL LRVEPERHMLLVAVHHIVFDGWSMGVFLQELSALYAAYASGETPRLAEPALQYRDFASW QRETLQGERLEQLLDYWSRRLEGAELTLELPTSKPRPPVQRFRGRTWTQRLGRPLIRQL EERGRAEGATLFMVLLAAFNTLLYRYTGQTGIAVGTPIAGRTRVELEEVIGLVMNSLVL YTDLT" CDS_motif complement(2866..2949) /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg245_2_0003" /evalue="2.30E-11" /label="C5_LCL_267-296" /locus_tag="ctg245_2" /protein_end="227" /protein_start="199" /score="36.1" /tool="antismash" /translation="IAVGTPIAGRTRVELEEVIGLVMNSLVLY" CDS_motif complement(3205..3243) /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg245_2_0002" /evalue="1.70E-05" /label="C4_LCL_164-176" /locus_tag="ctg245_2" /protein_end="114" /protein_start="101" /score="17.3" /tool="antismash" /translation="QYRDFASWQRETLQ" CDS_motif complement(3292..3357) /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg245_2_0001" /evalue="1.40E-13" /label="C3_LCL_132-143" /locus_tag="ctg245_2" /protein_end="85" /protein_start="63" /score="43.0" /tool="antismash" /translation="VHHIVFDGWSMGVFLQELSALYA" ORIGIN 1 ctccagcagg aacggctctc gcgagaccgc tgcggcttgc cgcttcacct ccagctcgcg 61 ctccgccggc ggccagtgcc gcaggtcctc gctcgaccac gcggcgcggc catccgccag 121 caccagctgc tcccgctccc cgtccgccgt ctcgcggatg accgtccgca gcgcttcgtg 181 gcgtccgacg atcgtctgga cgctgcgctc cagcgcctcc gcatccagtt gccctcggaa 241 ggctatgctc gccggcatat ggttgaccgg actgtccgga tcaagcgtat gcacgaacca 301 catccgatct tgggcaaatg acagcggcag cggggcctga ggagtcaatg cccctctcat 361 aagctcggat tgtccagcat tgacctcctc gagcagcgca gccaacaaca tctgcttggt 421 tgccgaccag cggttttggt tttggttatg accgccatcc tttgccgctt gcattcaatt 481 cactccttcc ccaacggatg aacgtacttt cagcctctct gccgcttcgg cttcggacat 541 cgcggtcagc tccaggattc gttccgccag cttggcgatc cgatcgcgat gctccgaggc 601 catcagcacc tcggccaagc ctcgaacggt aggatgctgg aacagctcca gcagcggcag 661 ctcgaattga aaccattgct tgatcctcgc cgtcacctgc gtagccagca gcgaattgcc 721 gccttgctcg aagaagctga tcaccggact cacggttccg atcttcagca cctcggcaaa 781 aatatccgcc agcacgcgtt caatcggtcc gtcgagtgct gcgcattcgt ccgcctgacg 841 agcgagcaag gcatcgcctg acaaggatag cgggtccggc aacgcgcgtt tatcgacttt 901 gccattccga gacaaaggaa gacggtcgag catcacccat atcgaaggaa tcatatattc 961 cggcagccgc tcggccagat gccgtcttat ctgagatacc gactcgggat gaccgccttg 1021 ggctgcaacg taggcgacca gccgccgatc atcgtcgccc gcatcccaca ccgtgacgac 1081 ggcctcggca atcgtctcgt gcgtaacgat cgccgcttcg atctccccga gctccacacg 1141 aaagccgcgg agcttgatct gattatcctc tctgccgata tattcaagct gaccatccgg 1201 acggtatcgt acaagatcgc cagtcctgta gagcacgcct tccccggcta gaggatgggc 1261 gataaatctc tcccgcgtca gctctggcct gccgtagtat tccttggcaa cttgtacgcc 1321 gccaatatac agctcgccga caaccccgat cggcacttgc tgcaaccgtt catcgagcac 1381 atgaagcgtc gtattccaga ccggacggcc gatagggacc gctccttctt gcccggtcgg 1441 cgggcatgtc caggacgtta cgtcgatggc tgcctccgtc ggaccgtaca gattatggag 1501 aagcgccggc gtgttcttgg cgcagaataa ctgaaccaat ggaagcgaca gtgcttcccc 1561 gctgcagaac acatgcctca aggaaggaca aagtgtctct gactctgcgg catcccgcag 1621 aaagacatgc agcatcgaag gcacgaaatg gatgactgat atgcggtgcc gatcgatcaa 1681 ccgttgcaaa taacgactgt ccttgtggcc ctctggcttg gcgacgacca gtcgggctcc 1741 tgaaataaga ggggcaaaaa attcccatac ggacacgtcg aacccgaagg gcgtcttctg 1801 caaaaagcaa tcgtctggcg taaacgcaaa gtggtgtttc atccatagca gtcggttggc 1861 caagccgata tgagtattga ccgctccttt cgggtgaccc gtggagcccg aggtatagat 1921 gagatacacc gggtcttgag gatggagcgc gcatgcggga ttgtccgcat cataacgctc 1981 cgcctccagc cgatccacct cgacgatctc catgccgggt tgaagcctcg gcacagcctc 2041 gagcaatcgg gatgacgacc gactgtctgt cacgacgaat tgaagctccg catcggctag 2101 catatattcc acccgtttgg caggattgcc gggatcgaca gggacatacg ccttgccagc 2161 cttaaggatc gccagcagcg acacgaccag ctccagactg cgatccatat agacaccgat 2221 aaatcgcgta tgctcggccg catgctcgag cagatacgag gctaattggt tagccctcct 2281 gttcaatgct tcatacgtca gcgtctcccc ctcgaacaca agcgcctccg cttcaggcgt 2341 ggcggccgct tgggcttcga actgcttatg cacatacggg acctgcggca gcgctgtcga 2401 cgtcgcattc cacgtctgga gctggatgcg ctcgcccggc gtcagcatcg gcagctcgcc 2461 gatccggcag tccgggtcgg cggcgatccc cgccagcagc gtctcgtagt ggcccgccat 2521 ccgctcgatc gcctcttgct cgaacagctc tgtgtcatac tcccatgcga tgaccagtcc 2581 ttgctcgctc tccgtcgcgc gcagcgtcag atcgtacttc gccgtcccgc tgtccagctc 2641 ttccacctgc atctctaccc cgggcagacc ctgcgcaggc atcggcgcat tttgcagcac 2701 gaacatcacc tggaacagcg ggctgcgact caggtcccgc tccggctgca gccgatccac 2761 cagcttctcg aacggcagct cctgatgcgc atatgccccg atcgccgtct ccttcacccg 2821 accgaccagc tcccggaacg tcggctcgcc cgtcaggtcc gtgtacagca ccagactgtt 2881 catcaccagg ccgatgacct cctccagctc cacccgcgtc ctccccgcga tcggcgtgcc 2941 gactgcgatc cccgtctgtc ccgtgtaacg gtacagcagc gtgttgaacg cggccagcag 3001 caccatgaac agcgtcgccc cctccgcgcg tccgcgctcc tcgagctgac ggatgagcgg 3061 cctccccaga cgctgagtcc aggtgcggcc acggaagcgc tgcaccggcg gccgcggctt 3121 gctcgtcggc agctccagcg tcagctccgc cccctccagc ctccggctcc agtagtcgag 3181 cagctgctcc agccgctccc cctgcagcgt ctcccgctgc caggacgcga agtcccggta 3241 ctgcagcgcc ggctctgcca ggcgtggcgt ctccccgctc gcataggccg catacagcgc 3301 cgacagctcc tgcaagaata cccccatcga ccagccatcg aagacgatat gatgcaccgc 3361 caccagcagc atatgccgct ccggctccac ccgcaacagc cgcgcgcgca gcagcggccc 3421 ctcctccagc aggaacggct ctcgcgagac cgctgcggct tgccgcttca cctccagctc 3481 gcgctccgcc ggcggccagt gccgcaggtc ctcgctcgac cacgcggcgc ggccatccgc 3541 cagcac //