LOCUS       c00141_3300012..       12631 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300012973.a:Ga0123351_1000946.
ACCESSION   c00141_3300012..
VERSION     c00141_3300012..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 07:27:22
            Original ID  :: 3300012973.a:Ga0123351_1000946
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12631
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12631
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[126:2631](-)"
                     /cutoff="20000"
                     /detection_rule="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C) or cds(LANC_like and (Pkinase or DUF4135)))
                     and not (YcaO or TIGR03882))"
                     /neighbourhood="10000"
                     /product="lanthipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(127..2631)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C) or cds(LANC_like and (Pkinase or DUF4135)))
                     and not (YcaO or TIGR03882))"
                     /neighbourhood="10000"
                     /product="lanthipeptide"
                     /protocluster_number="1"
     cand_cluster    1..12631
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C) or cds(LANC_like and (Pkinase or DUF4135)))
                     and not (YcaO or TIGR03882))"
                     /kind="single"
                     /product="lanthipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12631
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide"
                     /region_number="1"
                     /rules="((LANC_like and (Lant_dehydr_N or Lant_dehydr_C) or
                     cds(LANC_like and (Pkinase or DUF4135))) and not (YcaO or
                     TIGR03882))"
                     /tool="antismash"
     CDS             complement(3..164)
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg141_1"
                     /transl_table=11
                     /translation="LALTTHQHQRRCNDMVLLDLQSLEAPTGGGGGGGGSTLTVLGCQS
                     GKPSNLSVA"
     CDS_motif       complement(69..164)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     LALTTHQHQRRCNDMVLLDLQSLEAPTGGGGG"
                     /aSTool="lanthipeptides"
                     /locus_tag="ctg141_1"
                     /tool="antismash"
     CDS_motif       complement(3..68)
                     /core_sequence="GGGSTLTVLGCQSGKPSNLSVA"
                     /monoisotopic_mass="1924.0"
                     /prepeptide="core"
                     /predicted_class="Class III"
                     /aSTool="lanthipeptides"
                     /peptide="lanthipeptide"
                     /leader_location="[68:164](-)"
                     /molecular_weight="1925.1"
                     /score="10.10"
                     /locus_tag="ctg141_1"
                     /leader_sequence="LALTTHQHQRRCNDMVLLDLQSLEAPTGGGGG"
                     /alternative_weights="1943.2"
                     /alternative_weights="1961.2"
                     /alternative_weights="1979.2"
                     /alternative_weights="1997.2"
                     /alternative_weights="2015.2"
                     /tool="antismash"
     CDS             complement(127..2631)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide: Pkinase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide: LANC_like"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) micKC"
                     /gene_functions="regulatory (smcogs)
                     SMCOG1030:serine/threonine protein kinase (Score: 79.6;
                     E-value: 4.5e-24)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg141_2"
                     /sec_met_domain="LANC_like (E-value: 1.3e-08, bitscore:
                     24.8, seeds: 47, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 2.2e-13, bitscore: 41.0,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="micKC (E-value: 7.4e-235, bitscore: 772.5,
                     seeds: 18, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHYAPLDGRTPVQGWKIHVSARAEDADRAIEAVWDYCVPRDIAFK
                     FLRSLPVMTMLNSKAAPRGASGKLVTIYPVDEAQLELTLKELDELLTGVEGPYILSDLR
                     YGQGPLFVRYGGFAGRRCLADNGELVLAIEDGEGRLVPDVREPAFGVPPWVTLPAFLEP
                     HLAARNAVTTEGLPYRVESVMQFSNGGGVYLGEDLRTGERIVLKEARPYAGLDAAGRDA
                     VARLSHERDMLERLSGLDAVPALIDYFTLGGHHFLVEEFVDGNPLQRQLVHKYPLTRAT
                     CDDAAIADYTAWVLDMLPKVRRAVESLHERGVVFGDLHPNNILVTEDDRLVLIDYEVAT
                     LTEDRGRAALAHPAFGAPADRQGVDVDLYALSCLCLGLFAPQLTIMLPLDRTKVTELAR
                     LIGETFPVPREVLDEAVLTITGSKPATAASYPKPGRDSWPRLKEAMTRAILASATPERE
                     DRLFPGDVAQFQPGGGVNLAYGAAGVLYALASVGAERRPEHEDWLRAKALAPVPGTGIG
                     FYDGLHGVAYVLDLLGHRQDALDTADLCLRQKWEALELGLFSGLAGMGLNLLHLGRTTG
                     ERTFTEVALQITGICSDRLGGPEDVPEISGGVHPRAGLMYGSSGPALLFLHAYEHTGDA
                     ALLDRAAVALRQDLRRCVSGEDGTLQVNQGWRTLPYLDEGSVGIGIVLARYLAHREDED
                     LRAALDGCRRVTQGRYFVQSGLFTGRSGMIGTLGWGLGPEPNASPADHPDLAEQLRGLD
                     WHALPHGGGLAFPGNQLLRLSMDFATGTAGVLFAMSAVLHDRPVFLPFIEPPGDTGTPS
                     GAPAHESAGRFGPHDTSASKEV"
     CDS             2650..2835
                     /locus_tag="ctg141_3"
                     /transl_table=11
                     /translation="VLPAVRDISGSEREIGVITPAAIKRVIKERVGQAIKLILVIHDIL
                     PCCLPEQRITDNPRNH"
     CDS             complement(2832..2924)
                     /locus_tag="ctg141_4"
                     /transl_table=11
                     /translation="MFTFTTKAQVAHTFTVDTVSFAYATGLICN"
     misc_feature    complement(2844..2846)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     CDS             complement(2924..3649)
                     /gene_functions="regulatory (smcogs) SMCOG1048:sensor
                     histidine kinase (Score: 110.2; E-value: 2e-33)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg141_5"
                     /transl_table=11
                     /translation="MPHPAYLIGAVGTGILLISLGVTLTLALRIRRLHAEQERALSRAY
                     ERFARDMHDIVGHWLWLASIKGELARRKANGDARLREELEEVLQAVRQAAHAVRNVSEA
                     TRRLSFSGEVTRARTLMEGFGAYCSVRVDVDELPEVVSTALGAVVREGVTNMLRHSQVK
                     RCAIELVEYGGRLRLTVVNDGAPRRETPLTGAFGVASTGNGVDNLDHRVGELGGTVWAV
                     GGADGWFTLIAEVPAYFSE"
     CDS             complement(3885..4598)
                     /locus_tag="ctg141_6"
                     /transl_table=11
                     /translation="LSDLWVTLTTSRSGPPLWVVLLSALAALGVVSWSTSWQLSRGLIT
                     IAHEGGHALVALLTRRKLEGIRLHSDTSGVTLTRGKPRGFGMILTAAAGYVAPSLLGLG
                     GAWLTASGYVAVLITMVIGLLFCMLLLIRNLFGVASLLATGGAIFAFTWYAAPDMDAVL
                     AYLAVWFLLLGGIRPIVELQRKRRRHQAPDSDADQLARLTFLPGGFWVFLFLVVAGACV
                     VAGAYLLLPSALGLG"
     CDS             complement(4580..4864)
                     /locus_tag="ctg141_7"
                     /transl_table=11
                     /translation="LSAFCQRSAWIRPSSGLPDGVGPAGVGVGDVRETAAKRDLAGPAR
                     FSPAGGTARVREFRHHIRHGSDFIPSTPAVVGRFTLTPRRRNERCPTSG"
     CDS             4927..5403
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF07366"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg141_8"
                     /sec_met_domain="PF07366 (E-value: 2.9e-15, bitscore: 47.0,
                     seeds: 29, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VNDRNAELIKTFYEAFARRDVDAMERCYHPDVTFGDPVFQDLEGR
                     DKVMGMWRMLLSRSPDLTVTVRDITARPHEGAAHWTGRYTFGEKGRKVVNEVDALFRFE
                     DGLIIRHHDDFDLRRWSKMAMGRPVGIVLGWTPMLRAKIRTTAMRSLQEFMSAR"
     CDS             5413..6561
                     /locus_tag="ctg141_9"
                     /transl_table=11
                     /translation="VTDRRMRGLRSLMRGRSADTGRESPERSMDPRSAGERRPVPPRSR
                     VIDNAIYVNGHRAATPESLPEAFERLKNTPDSMAWIGFYRPEDSVILNVAEEFDLHELA
                     VEDAIVAHQRPKADRYGDTLFVVLRPARYLDETEEVDFGELHLFVGKNFVITVRHSEAP
                     DLSQVRRRMQRDPELLGQGPQAVLYAVLDAVVDGYAPVVAGLQNDIDEIEVQVFGNEPG
                     VSRRIYELSREVIEFQRATQPLLDMVEGFIAGAEKYGVDQELQRYLRDVADHVITVAER
                     VSGFRQMLHDILVVNSTMVAQAQNEHMTNLTEASNAQNEEVKRISAWAAILFAPTLVGT
                     IYGMNFDVMPEIHWAWGYPFAIMLMAGVCLSLYLVFKRRDWL"
     CDS             complement(6609..8873)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1110:1-deoxy-D-xylulose-5-phosphate synthase (Score:
                     292.2; E-value: 5.6e-89)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg141_10"
                     /transl_table=11
                     /translation="MSRSGTASVDGGHNRAVARDTVETHFTEAVSALSPGAPRDPGLPV
                     RDDTTLTGARCRELFEFQLGSRLLDVTARRLREQGEGFYTIGSAGHEGNAAVAAALRVT
                     DPALLHYRSGAFYLTRSAMAGRLPEEGLRDVLLGLTASAEEPIAGGRHKVFGHPDLAVI
                     PQTSTIASHLPRSVGVAFAIERARQLGVPGPWPSDAIVICSFGDASTNHASALSGLNTA
                     AYGSYQKLPLPILFVCEDNGLGISVRTPDGWVKAARHPLMRYFEADGCDLADVHDMALA
                     AADHVRTHRAPALLRVSTVRLMGHAGSDVELSYRTKREIDADLARDPLVATARLLVEAG
                     LTTPGDLLIRYETTREHLFKTAMVSSRRPRLVSAFDIVEPLAPRTPAAVAAACTEVAAA
                     DVRSRAFAGRLPEGEGPLTFSQAVNRTLADSLAAHPDVLVFGEDVARKGGVYGVTRGLQ
                     KRFGPGRVFDTLLDEQSVLGLALGSGVSGLLPVPEIQYLAYLHNALDQIRGEAATLQFF
                     SQGAFRNPMVVRVASYAYQKGFGGHFHNDNSIAALRDIPGLVVASPARPDDAASMLRTC
                     LAAARVDGSVCVFLEPIALYNTRDMFEEGDNGWLSPYAPPARWAETHIPIGRARSYGDG
                     RDLTIVTFGNGLRMSLRAAVRLTAEGHSCRVLDLRWLSPLPVEDLMRAAELTGRVLIAD
                     ETRRTGGVSESIVAELLDAGFTGRIARVTSSDSFIPLGEAARHVLLSEAEIEAAARKLL
                     G"
     CDS             complement(9001..10011)
                     /locus_tag="ctg141_11"
                     /transl_table=11
                     /translation="LTSPYLIRARRSRARDGHRREPVTGTGTGRRSAARAGYRHGPATV
                     TTPVGEQSASAHAATADVTASGVPGAAKITGVDTPWTGGTAAGGVTSTGGVAPGVVVST
                     GGMASGGVVPGSVVSTDEVPSGSVVSTGEVPSGSVVSGVSASSGGVPGTAAVGTGVVPC
                     AGAGGGGVAPEGDSADTGVRGLPYAGALPVAAVSPESAVTGRAVSGNGSAAWAAAGSMT
                     TAPTAPVRINFPSMRVSTRVTDAMNVNSEDAGSRSTRRWQRDPPREVRRRNGLWQQGRE
                     IPMDRNTSPKTNTLTPFGASALSEGDSAWEVGRRSPAQDPRAAVSHPSSGVGASA"
     CDS             10262..11128
                     /locus_tag="ctg141_12"
                     /transl_table=11
                     /translation="MPVRDEGRPVVVGYDGSAESRLALRWAVEDARLRFLPLLVCHAWQ
                     WPYPRLSLAPETTEVVRRMGGRVLESGLIAARELAPKVPVRGRLVEGTPAAALVGLSNA
                     AELIVIGPRGAGDPEELRIGSTVEVAAHAHCPVAVVRRPGHPRVGRVAIAVENAAVDSQ
                     ELAIAFEEARLRRAALLIICLCSEDTGDLRSAAVHFHTNVAVWEERYPTVVVETMIETR
                     PHVEVLRHAADRSDLLVVADREHHDPLDPVIGPVCQAMLREAPCAVVVTPSQAWSPSVR
                     AELFSRS"
     CDS             complement(11135..11536)
                     /locus_tag="ctg141_13"
                     /transl_table=11
                     /translation="MLLDVSERLHASGARRVTEAADAEQALDALLGCQIEFALSHPALI
                     TVHDRELGNVPEPARRRIRRLQRLYVEEWVTVLSELYPARSQAGLRAATHAVFGLLNST
                     PHSAGELPPAAMAELLRGMARAALAAAQG"
     CDS             11556..11762
                     /locus_tag="ctg141_14"
                     /transl_table=11
                     /translation="LPLKWRYRAGPEVPTAPPISSIETPWKPRAAKSSAAASRISARRE
                     PRLRAGDRAVVTSRMVDGNVNND"
ORIGIN
        1 agggcgacgc tcaggttgct gggcttgccg gactggcagc ccaggaccgt gagggtgctg
       61 ccgccgccac cgccgccacc gccggtgggg gcttccaggg actgcaggtc gagaaggacc
      121 atgtcgttac acctcctttg atgctgatgt gtcgtgaggg ccaaaccgtc cggcggattc
      181 gtgcgcgggc gcccctgacg gggtgcccgt gtcgccgggc ggttcgatga aggggaggaa
      241 caccggccgg tcgtgcagca cggcgctcat cgcgaacagg actccggccg tgccggtcgc
      301 gaagtccatg gagagcctga gcagctggtt gccggggaag gcgagcccgc cgccgtgggg
      361 cagcgcgtgc cagtccagcc cgcggagctg ttcggccagg tcagggtggt cggcagggga
      421 ggcgttcggc tcgggtccca gaccccagcc gagggtgccg atcatgccgc tccggccggt
      481 gaacaggccg gactgcacga agtagcgtcc ctgggtgacg cgccggcagc cgtcgagcgc
      541 ggcgcgcagg tcctcgtcct cccggtgggc caggtaacgg gcgaggacga tgccgatgcc
      601 caccgacccc tcgtccaggt agggcagcgt gcgccagccc tggttgacct ggagggttcc
      661 gtcctcaccg ctgacgcagc gccgcaggtc ctgccggagc gccacggccg ccctgtcgag
      721 cagcgccgcg tcgccggtgt gctcgtaggc gtgcaggaag agaagagcgg gcccggagga
      781 gccgtacatc agcccggctc gggggtggac gccgccgctg atctcgggta cgtcctcggg
      841 cccgcccagc ctgtcggagc agatgccggt gatctgcagg gccacctcgg tgaaggtccg
      901 ctctccggtg gtccgcccca ggtggaggag gttcaggccc atgccggcca ggccgctgaa
      961 cagcccgagc tccagcgcct cccacttctg gcgcaggcac aggtcggcgg tgtcgagcgc
     1021 gtcctggcgg tgcccgagca ggtcgaggac gtaggccacg ccgtgcaggc cgtcgtagaa
     1081 cccgatcccc gtccccggga cgggggcgag cgccttcgcg cgcagccagt cctcgtgctc
     1141 gggacggcgc tcggctccga cgctcgccag cgcgtagagc acgccggccg cgccgtacgc
     1201 gaggttgacg ccaccgccgg gctggaactg ggcgacgtcg ccggggaaga gccggtcctc
     1261 gcgctcgggc gtggcgctcg ccaggatggc ccgggtcatc gcctccttga gccggggcca
     1321 gctgtcgcgt cccggtttcg gataggacgc ggccgtcgcg ggtttggagc ccgtgatggt
     1381 gaggaccgcc tcgtcgagca cctcgcgcgg tacggggaag gtctcgccga tgagcctggc
     1441 cagctcggtc accttggtgc ggtcgagcgg cagcatgatc gtgagctggg gggcgaagag
     1501 cccgaggcag aggcaggaga gggcgtacag gtcgacgtcg acgccctgcc ggtcggccgg
     1561 cgcgccgaac gccgggtggg cgagcgccgc gcggccgcgg tcctcggtga gggtcgccac
     1621 ctcgtagtcg atcaggacca ggcggtcgtc ctcggtcacg aggatgttgt tcggatgcag
     1681 gtcgccgaag accaccccgc gctcgtgcag ggactcgacc gcccggcgca ccttgggaag
     1741 catgtcgagc acccaggcgg tgtagtcggc gatggccgcg tcgtcgcagg tcgccctggt
     1801 gagcgggtat ttgtgcacga gctgccgctg gagcgggttg ccgtcgacga actcctcgac
     1861 caggaagtgg tgcccgccca gggtgaagta gtcgatcagt gcgggcaccg cgtccagccc
     1921 ggacaggcgc tccagcatgt cgcgctcgtg cgacagccgc gccaccgcgt cccggccggc
     1981 ggcgtccagg ccggcgtacg ggcgggcctc cttcagcacg atccgttccc cggtgcgcag
     2041 gtcctctccc aggtagacgc cgccgccgtt ggagaactgc atcacgctct cgacccggta
     2101 cggcagcccc tcggtggtga ccgcgttgcg ggctgccagg tggggttcga ggaaggcggg
     2161 cagcgtcacc cagggcggca caccgaaggc gggctcccgc acgtcgggga cgagccggcc
     2221 ctcgccgtcc tcgatggcca gcaccagttc gccgttgtcg gccaggcagc gccgtccggc
     2281 gaacccgccg taccgtacga acagcggtcc ctggccgtag cggaggtcgc tgaggatgta
     2341 gggtccctcg acgcccgtga gcagctcgtc gagctccttg agcgtgagct ccagctgcgc
     2401 ctcgtccacc gggtagatcg tcacgagttt cccgctggcg ccccgggggg cggccttgga
     2461 gttcagcatg gtcatgaccg gcaggctgcg caggaacttg aacgcgatgt cgcgggggac
     2521 gcagtagtcc cagaccgcct ctatggcgcg gtcggcgtcc tcggcgcgag cggagacgtg
     2581 gatcttccag ccctggacgg gtgtgcgacc gtcgagcggt gcgtagtgca tccaggtctc
     2641 ggtcgcctgg tgctgccagc cgtccgggac atctcgggca gcgagcgcga aatcggggtg
     2701 atcaccccgg cggccatcaa gcgtgtcata aaagagcggg tcggccaggc aataaagctc
     2761 atactggtca tccacgacat tctcccctgc tgtcttccag aacagagaat tacggataac
     2821 ccgagaaacc actagttaca aattaaacca gtcgcatatg cgaaactcac agtgtcgacc
     2881 gtgaaggtgt gcgctacctg cgctttcgtg gtaaacgtga acatcattca gaaaaatatg
     2941 caggaacctc ggctatcaga gtgaaccacc catccgcgcc gccgaccgcc cataccgtgc
     3001 cgcccagctc gcccacgcgg tggtccaggt tgtccacgcc gttgccggtg gaagcgaccc
     3061 cgaaggcacc tgtgaggggt gtctcccgcc ggggagcccc gtcgttgacg acggtcaggc
     3121 gcagccggcc gccgtactcg accagctcga tcgcgcaccg cttcacctgg ctgtgccgca
     3181 gcatgttcgt cacgccctcg cgaaccacgg cgcccagcgc ggtgctcacg acctcgggaa
     3241 gctcgtccac gtcgacgcgg accgagcagt aggccccgaa gccctccatc agggtcctgg
     3301 cccgcgtgac ctcgccggag aacgacagcc ggcgggtggc ctccgacacg ttccgcacgg
     3361 cgtgcgcggc ctgccgcacc gcctgcagca cctcttccag ctcctcacgc agacgcgcgt
     3421 cgccgttcgc cttccggcgg gccagctctc ccttgatgga cgccagccag agccagtgcc
     3481 ccacgatgtc gtgcatgtcg cgggcgaatc tctcatacgc gcggctgagt gctcgctcct
     3541 gctcggcgtg gagccgtctg atccgcaggg cgagggtgag cgtcacgccc aacgagatca
     3601 acaggatgcc cgttccgacc gctccgatga ggtaagcggg gtggggcatg gaacgcctct
     3661 cgcaggagaa atgatattcc cgctaataaa ctcaaaaaag tgcttgaatg tcaatcaaga
     3721 ggcatggttc catgctatgg tacggcagga tggggatcgc catgaaatca gcgtgaaatg
     3781 cggtgatata gcccgcctaa ttctccgtcg agagaatcgt aatcgccgtg cctccccatg
     3841 cggggacggt gaacgacggg cacggagtgc ccgcgcgaga cctcttagcc gagcccgagc
     3901 gccgagggca gcagcagata cgctccggcc accacgcacg cgcccgccac caccagaaac
     3961 aggaagaccc agaatccacc gggcaggaag gtgagcctgg cgagctggtc ggcgtcggag
     4021 tcgggcgcct gatggcggcg ccgcttgcgc tggagttcca cgataggccg tataccgccc
     4081 agcagcagga accacacggc caggtaggcg aggaccgcgt ccatgtcggg cgccgcgtac
     4141 caggtgaagg cgaagatcgc tcctccggtg gcgagcaggc tcgccacgcc gaacaggttg
     4201 cggatcagca gcaacatgca gaacagcagc ccgatcacca tcgtgatcag caccgccacg
     4261 tagccggagg cggtgagcca cgccccgccc agccccagca gggacggagc gacgtatccg
     4321 gcggcggcgg tcaggatcat gccgaaccct cgcggctttc ccctggtcag ggtgacgccc
     4381 gaagtgtcgg agtgcagccg gataccctcc agtttgcgcc gggtgagcag cgccaccagc
     4441 gcgtgcccgc cctcgtgggc gatggtgatc agccctcgcg acagctgcca cgaggtggac
     4501 cacgacacca cgcccagcgc ggccaaagcg gacagcagca caacccacag gggtggcccg
     4561 gaacgggacg tggtcagggt cacccagagg tcggacaacg ctcgtttctc cttcgcggcg
     4621 tgagagtaaa gcgtcccacg actgccggtg tgctggggat aaagtcggaa ccgtgccgaa
     4681 tatgatgccg gaattcgcgg acgcgggcgg ttccgcccgc aggcgagaac cgggcaggac
     4741 cggcgagatc ccgcttggcg gcggtctccc ggacatcccc cacccctacg cccgccggcc
     4801 ccacgccgtc cggcaggccc gacgacggcc gaatccacgc gctgcgctgg caaaacgcgg
     4861 acaatcttcg tggctcctcc gcgcactaca ctcggtcggc aggacattga tggtcgggag
     4921 aaactcgtga acgatcggaa cgccgagctc atcaagacgt tctacgaggc attcgcgcgc
     4981 cgtgacgtcg acgcgatgga gcgctgctac caccctgacg tcaccttcgg tgaccctgtc
     5041 ttccaggacc tcgaaggacg cgacaaggtc atgggcatgt ggcggatgct gctgagccgc
     5101 agccccgacc tcaccgtgac cgtgcgtgac atcaccgccc gcccccacga gggcgcggcg
     5161 cactggaccg gtcgttacac cttcggtgag aagggcagga aggtcgtcaa cgaggtcgac
     5221 gccctcttcc gcttcgagga cggactgatc atccgccacc acgacgactt cgacctgaga
     5281 cgctggtcca agatggcgat gggcaggccg gtcgggatcg tcctcggctg gaccccgatg
     5341 ctgagggcga agatccgtac caccgcgatg cggtcgctgc aggagttcat gagcgcccga
     5401 taggagagac gtgtgaccga ccggcgaatg cgcggcctgc ggagcctgat gcgcgggcgt
     5461 tccgccgaca ccggtcggga gtctcccgag cgatcgatgg accccagatc cgcgggagag
     5521 aggcggccgg tcccgccccg ctcacgcgtc atcgacaacg cgatctacgt caacggccat
     5581 cgggccgcca cccccgagtc gctgcccgag gcgttcgaac gcctgaagaa caccccggac
     5641 agcatggcct ggatcggctt ctaccggccg gaggacagcg tcatcctcaa cgtcgccgag
     5701 gagttcgacc tgcacgagct cgcggtcgag gacgccatcg tcgcccacca gcgccccaag
     5761 gccgaccgct acggcgacac cctgttcgtg gtgctccgcc cggcccgcta cctcgacgag
     5821 acggaggagg tcgacttcgg cgaactgcac ctcttcgtcg gcaagaactt cgtgatcact
     5881 gtacggcaca gtgaggcgcc cgacctgtcc caggtccgcc gccgcatgca gcgcgacccc
     5941 gaactgctcg gccaggggcc gcaggcggtg ctctacgccg tcctcgacgc ggtcgtggac
     6001 ggctacgccc ccgtggtcgc cggtctgcag aacgacatcg acgagatcga ggtccaggtc
     6061 ttcggcaacg agcccggcgt ctcccgccgc atctacgagc tgtcgcgtga ggtgatcgag
     6121 ttccagcggg ccacccagcc gctcctggac atggtcgagg gtttcatcgc gggggcggaa
     6181 aaatacgggg tggaccagga gctgcagaga tacttgcggg acgtggccga ccacgtgatc
     6241 accgtcgccg agcgggtgag cggcttccgt cagatgctcc acgacatcct cgtggtcaac
     6301 tcgaccatgg tcgcccaggc tcagaacgag cacatgacca acctcaccga ggcgagcaac
     6361 gcccagaacg aggaggtcaa gcggatctcc gcgtgggccg cgatcctgtt cgcccccacc
     6421 ctcgtcggca ccatctacgg catgaacttc gacgtgatgc ccgagatcca ctgggcgtgg
     6481 ggctacccct tcgcgatcat gctcatggcg ggcgtctgcc tctccctcta tctggtgttc
     6541 aaacgccgag actggttgtg aacccgtcgt gagccccgga ccgccggccc gaggcccatc
     6601 ggcgaggatc agccgagcag cttgcgggcg gccgcctcga tctcggcctc cgacagcaac
     6661 acgtgcctcg ccgcctcgcc cagcgggatg aagctgtccg aggaggtcac ccgggcgatc
     6721 ctgccggtga aacccgcgtc gagcagctcg gcgacgatgc tctcagagac acccccggtg
     6781 cggcgggtct cgtcggcgat cagcacccgg ccggtcagct ccgcggcccg catcaggtct
     6841 tccaccggca ggggagagag ccagcgcagg tccagcaccc ggcagctgtg cccctccgcg
     6901 gtgagcctca ccgcggcgcg caggctcatc cgcagcccgt tgccgaaggt cacgatggtc
     6961 aggtcacggc cgtcgccgta gctgcgggca cgtccgatcg ggatgtgtgt ctccgcccat
     7021 cgggcaggag gggcgtacgg ggagagccag ccgttgtcgc cctcctcgaa catgtcgcgg
     7081 gtgttgtaca gggcgatggg ctcaaggaag acgcagacgc tgccgtcgac gcgggcggcg
     7141 gcgaggcagg tgcgcagcat cgaggcggcg tcgtcgggcc gggcggggga ggccacgacc
     7201 aggccgggta tgtcgcgcag cgcggcgatg gagttgtcgt tgtggaagtg gccgccgaag
     7261 cccttctggt aggcgtagga ggcgacgcgc accaccatcg ggttgcgaaa ggccccctgg
     7321 gagaagaact ggagcgtcgc ggcctcgccc cggatctggt ccagggcgtt gtgcaggtag
     7381 gccagatact ggatctcggg caccggcagc agaccggaga cccccgagcc gagcgcgagg
     7441 ccgagcacgg actgctcgtc gaggagagtg tcgaacaccc ggcccgggcc gaagcgtttc
     7501 tgcaggccgc gcgtgacgcc gtagacgccg cccttgcgtg ccacgtcctc gccgaagacg
     7561 agcacatcgg ggtgggcggc gagggagtcg gcgagggtgc ggttgacggc ctgggagaag
     7621 gtgagcgggc cctccccctc ggggagcctg ccggcgaagg ccctcgacct gacgtcagcg
     7681 gccgccacct cggtgcaggc cgcggcgacg gcggcggggg tgcgcggggc gagcggctcc
     7741 acgatgtcga aggcggagac cagccggggg cgccgcgagc tcaccatcgc cgtcttgaac
     7801 aggtgctcgc gcgtcgtctc gtaccggatc agcagatcgc cgggagtggt cagaccggcc
     7861 tcgacgagca gcctggcggt cgcgacgagc gggtcacgcg ccaggtcggc gtcgatctcc
     7921 cgcttggtcc gatacgacag ctccacgtcc gagcccgcgt ggcccatcag ccggacggtg
     7981 ctcacgcgca gcagggcggg cgcgcggtgc gtgcggacgt ggtcggcggc ggccagcgcc
     8041 atgtcgtgga cgtcggcgag gtcacagccg tcggcctcga agtatctcat caacgggtgg
     8101 cgggcggcct tgacccagcc gtcgggggtg cgcacgctga tgcccaggcc gttgtcctcg
     8161 cagacgaaga ggatcggcag cggcagcttc tggtacgagc cgtaggcggc cgtgttgagg
     8221 cccgacaacg cgctggcgtg gttggtcgag gcgtcgccga agctgcagat cacgatcgcg
     8281 tcgctcggcc acggtcccgg cacgccgagc tggcgggcgc gctcgatggc gaaggccacg
     8341 cccaccgagc ggggcaggtg actggcgatc gtggaggtct gggggatcac cgcgaggtcc
     8401 gggtggccga agaccttgtg ccgtccgccc gcgatcggct cctcggccga ggcggtcagg
     8461 ccgagcagca cgtcgcgcag cccttcctcg ggcaaccgtc ccgccatcgc cgacctggtc
     8521 agatagaagg cgcctgaccg gtagtgcagg agggccggat cggtgacgcg caacgcggcg
     8581 gcgaccgcgg cgttgccctc gtgcccggcc gagccgatcg tgtagaaccc ctcgccctgc
     8641 tcgcgcagcc ggcgggcggt gacgtccagc agcctgctgc cgagctggaa ctcgaacagc
     8701 tcgcggcacc tggccccggt cagggtggtg tcgtcccgca cgggcaggcc gggatcgcgc
     8761 ggtgctccgg gggaaagggc actcacggcc tcggtgaaat gggtctcaac agtgtcgcgc
     8821 gccacagccc gattatgtcc cccatcgacg gacgccgtcc ccgaccttga catttttgat
     8881 gcgtacaaga tggtggaacg atcgcactta accgatattc atgacagttt gtcaggcgct
     8941 atttcgtggt ccgttcgacg aatgaaccgg aacttcaagc ctggcacccc gtgccggccc
     9001 tcaggccgag gccccgacgc cggaactcgg gtgcgaaacc gcggcgcggg ggtcctgggc
     9061 aggactccga cggcccacct cccaggcaga gtcgccctca gagagggcgg aagccccgaa
     9121 cggtgtgagc gtattcgttt tcgggcttgt gttccgatcc atgggtatct cgcgcccctg
     9181 ttgccacaaa ccgttcctcc tgcggacttc tcgcggaggg tccctttgcc atcggcgggt
     9241 actgcggctg ccagcatctt cggagttcac gttcatcgca tcagtcacac gagtggagac
     9301 gcgcatgctt ggaaaattga ttctcaccgg ggcggtggga gcggtcgtca tgctgccggc
     9361 cgccgcccac gccgccgaac cgtttccgga tacggcgcgc ccggtcacgg cgctttccgg
     9421 tgacacggcg gccaccggga gcgcaccggc gtacggaagc ccgcggacgc cggtgtccgc
     9481 gctgtcgccc tcgggtgcga cgccgcctcc gcccgcacct gcgcagggga ccaccccggt
     9541 gcccacggcc gcggtgcccg ggaccccgcc cgacgaggcg ctcacgcccg atacgaccga
     9601 gcccgatggc acttcgccgg tggacacgac cgagcccgat ggcacttcgt cggtggacac
     9661 gaccgagccc ggcaccactc cgcctgacgc catcccgccg gtggacacga ccacacccgg
     9721 tgccaccccg ccggtcgacg tcacaccccc cgcggccgtc ccgccggtcc agggggtgtc
     9781 gacgccggtg atcttcgccg cgccgggtac gccgctcgcg gtcacgtcgg ccgtcgccgc
     9841 atgggcggaa gcgctctgct cgccgaccgg tgtcgtgacc gtggccggtc cgtgcctgta
     9901 accggctcgc gccgctgacc gccgtcccgt gcccgtaccc gtgacgggct cacgccggtg
     9961 accgtcccgt gcccgtgacc gtcgcgcgcg gatgaggtac ggcgacgtca acggtgtcct
    10021 ctcgacgacc gtgccggtga ccggccgccg agccactccg gcagattcgt gcggcccgtg
    10081 cggcccgcgc gaaacccctc ccggccccgg ccggtcctga agcgccctcc cgtcccccgg
    10141 gcgggggaag gcatttttgc cgatatgagg cgcaaaacga gaagagtctt gggaaagcac
    10201 gccctgttcg gtgggcggac tcggagaagg atgaaaggag cgacgcggga gaggagccgt
    10261 catgccggta cgggacgagg ggcgaccggt ggtcgtcgga tacgacggct cggcggagag
    10321 ccgcctggcc ctgcggtggg ccgtcgagga cgcccgcctg agatttctcc cgttgctcgt
    10381 ctgtcacgcc tggcagtggc cctatcccag gctctccctc gcccccgaga ccaccgaggt
    10441 cgtacggcgg atgggcgggc gtgtcctgga gagcgggctg atagccgcgc gcgaactggc
    10501 gcccaaggtg cccgtgcgcg ggcggctggt ggaggggacc ccggccgccg ccctggtggg
    10561 cctgtcgaac gccgcggagc tgatcgtgat cggcccgcgt ggcgcgggcg accccgaaga
    10621 actgcggatc ggatcgaccg tcgaggtcgc cgcgcacgcc cactgcccgg tggccgtcgt
    10681 caggagaccg ggccatccgc gcgtcggccg cgtggcgatc gcggtggaga acgccgccgt
    10741 cgactcgcag gaactggcca tcgccttcga ggaggcgagg ctgcgcaggg cggcgctgct
    10801 catcatctgc ctctgttccg aggacaccgg cgacctcagg tcggcggccg tccacttcca
    10861 caccaacgtc gcggtgtggg aggagaggta tcccacggtc gtggtggaga cgatgatcga
    10921 gacacgacct cacgtcgagg tgctccgcca cgcggccgac cgttcggatc tgctggtggt
    10981 cgccgaccgg gagcaccacg atccgctgga tcccgtgatc ggcccggtct gccaggcgat
    11041 gctgcgtgag gcgccgtgcg cggtcgtggt gaccccctcg caggcgtgga gtccgtccgt
    11101 ccgggcggag ctgttctcca ggagttagca gtcactaacc ttgggcggcg gccagcgccg
    11161 cacgtgccat accgcgcagc agctcggcca tcgccgcggg cggcagctcg cccgcgctgt
    11221 gcggggtgga gttgagcagt ccgaagacgg cgtgggtcgc ggcgcgcaac ccggcctggg
    11281 agcgcgcggg gtagagctcg ctcagcacgg tgacccactc ctcgacgtac agccgctgca
    11341 gccggcggat cctccggcgc gcgggctcgg gcacgttgcc gagctccctg tcgtgcacgg
    11401 tgatcagcgc cggatggctg agcgcgaact cgatctgaca gccgagaagg gcgtccagtg
    11461 cctgctcggc gtcggcggcc tcggtcacgc ggcgcgcgcc cgaggcgtgc aggcgctcgc
    11521 tgacatccag cagcatctcc gcgagcaggg cgtccttgcc gctgaagtgg cgatacaggg
    11581 ccggccccga ggtgccgacc gcgccgccga tctcctcgat cgagacgccg tggaagccgc
    11641 gggcggcgaa gagctccgct gcggcgtcca ggatctccgc gcgccgggag ccacggttgc
    11701 gtgcggggga ccgagcagtc gtcacctctc gcatggtaga cggtaacgtt aataatgact
    11761 aacatctgcg gtgaggctgg gtgtcgatgt ctcggtgacg gcggagccgg ggcagatcgg
    11821 atgatccggg cggagcggac ggggaggctc gtatgagtgg ctggccggtg ctgcggagcg
    11881 cctgtgaccc gggaggtgag ggtttcaagc gcaacgccga ggtgaacgag cgcctggtcg
    11941 ccgacctcag ggagcgcctc gccgtggcgg ggctgggcgg ccccgagaag tcgcgcgccc
    12001 ggcatgtcgc ccggggcaag ctgctgcctc gcgaccgcgt cgactcgctg ctcgaccccg
    12061 gctcgcgttt cctggagctc tcccagctgg ccgcgggagg gatgtacggc gacgtggcgc
    12121 ccgccgcggg gatcatcacc ggggtgggcc gtgtctccgg gcgcgagtgc gtggtcgtcg
    12181 ccaacgacgc caccgtcaag ggcggcacct actatccgat caccgtcaag aagcatctgc
    12241 gggcccagga ggtcgccctc cacaacaacc tgccgtgcct ctatctcgtc gactcgggag
    12301 gcgcgttcct gcccaggcag gacgaggtct tccccgaccg cgagcacttc ggccggatct
    12361 tctacaacca ggcgaccatg tccgcgcgcg gcatcccgca gatcgccgcg gtcctcggct
    12421 cctgcacggc gggcggcgcg tacgtcccgg cgatgagcga cgaggcggtg atcgtccgca
    12481 accagggcac gatctttctc ggcggcccgc cgctggtgaa ggccgccacc ggcgaggagg
    12541 tcaccgcgga ggagctgggc ggcggcgacc tgcacgcccg cgtcagcggc gtcaccgacc
    12601 acctcgccga cgacgaccgc cacgcgctgc g
//
