LOCUS       c00006_3300013..        3818 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300013004.a:Ga0164293_10040446.
ACCESSION   c00006_3300013..
VERSION     c00006_3300013..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-24 12:20:15
            Original ID  :: 3300013004.a:Ga0164293_10040446
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 3818
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..3816
                     /NRPS_PKS="Domain: CAL_domain (18-464). E-value: 7.6e-139.
                     Score: 455.2. Matches aSDomain:
                     nrpspksdomains_ctg6_1_CAL_domain.1"
                     /NRPS_PKS="Domain: ACP (602-670). E-value: 5e-17. Score:
                     53.8. Matches aSDomain: nrpspksdomains_ctg6_1_ACP.1"
                     /NRPS_PKS="Domain: PKS_KS(Hybrid-KS) (698-1113). E-value:
                     4.8e-191. Score: 626.9. Matches aSDomain:
                     nrpspksdomains_ctg6_1_PKS_KS.1"
                     /NRPS_PKS="type: PKS/NRPS-like protein"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) hyb_KS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     389.4; E-value: 3.5e-118)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg6_1"
                     /sec_met_domain="AMP-binding (E-value: 2.1e-99, bitscore:
                     318.9, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 7.7e-17, bitscore:
                     47.9, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="hyb_KS (E-value: 3.2e-201, bitscore:
                     654.8, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="EQTAYIFLANGETETARLTYQQLEQKAKALAAQLQLQMSPGERAL
                     LLYPSEEEFIIAFFACLYAGVIAVPVYPPRRNQKLSRLQAITKDAQAKLALTTTSLLST
                     IEEKFSSDPELVTVPCLATNNIPDKQAENWQKPNLSLEDIAFLQYTSGSTGMPKGVMVS
                     HKNLLHNEKLIASAFGHTSETIGVGWLPLFHDMGLIGNVLQPVYVGFPCVIMPPEAFIQ
                     KPLRWLQAISRYNATSSGGPNFAYELCADKINPQERENLDLSCWDVAFTGAEPVRAATL
                     EKFANTFADYGFKREAFYPCYGMAETTLFVSGGIKNQSPVIAAVDKLALLENSAVTINS
                     QHPNAQLLVGCGHAWLSEKIVIVNPESLTECRDGEIGEIWVSSDSVAQGYWNRPEQTAE
                     TFKAYLADTQVGPFLRTGDLGFLLAGELFITGRLKDLIIVQGRNHYPQDIESTVEKSYP
                     GLRQGCGAVFSVEIAGQERLVVVQEVERSYLRKLDSPAVIEQIIRSVAEEHQLDVYAVA
                     LLKTASIPKTSSGKIQRQACRASFLAGTLNVIGDWSKNPEHKNGFKQLKSDINSLLKQV
                     KSYQVVEEFSEVSQNQIVSDTQEAIEEWLIKKVAEILQIAPEKIDIQQDLASYGLSSLA
                     AVSLSGELEQWLGKSVSPMLVYEYPSIHAVARYLALNGLSSEALATTSSTVAQKTSSQP
                     QNEPIAIIGIGCRFPKAKDPETFWQLLRQGVDGITEVSSQRWNYQDFGHLNTRWGGFLE
                     NVYDFEPQFFGIAPREAVDMDPQQRLLLEVSWEALENACIAPETLAGSQTGVFIGISTN
                     DHARLLSQDNESIDAYYGTGNAFCVAANRLSYFLDFHGPSLAIDTACSSSLVAVHEACK
                     SLTDGECHLALAAGVNLLLSPQLTINFSKAGMLASDGHCKTFDESADGYVRGEGCGVVI
                     LKRLEDAIKDGDRIYAIIRGSAVNQDGHSNGLTAPNKQAQKAVIKKALAKAQVSAKDIS
                     YVEAHGTGTSLGDPIELNTLKEVLMQDRQLSNPCWIGSVKTNIGHLEAAAGIAALIKVC
                     LALQNREIPPHLHLQKLNPYISLEGTSLSIPTQLQPWKKGKKGRLAGVSSFGFGGTNAH
                     VILEEFVPETLEQEQHEPSLAILTITAKTKSSLRELVSSYHNYLQANPQINLQDFCFSA
                     DVGRSHFHHCLAIQTESLTQLQSQLEAIIEGKEAGGILTGELSHQKHQKIAFLFTGQGS
                     QYINMARELYETQPTFRRTLEHCQEILSIYLDKPLLSILYPQEGENS"
     protocluster    1..3818
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[0:3816](+)"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1..3816
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
     cand_cluster    1..3818
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /kind="single"
                     /product="NRPS-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..3818
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS-like"
                     /region_number="1"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX))"
                     /tool="antismash"
     CDS_motif       10..45
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg6_1_0001"
                     /evalue="9.90E+01"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg6_1"
                     /protein_end="15"
                     /protein_start="3"
                     /score="-3.2"
                     /tool="antismash"
                     /translation="AYIFLANGETETA"
     aSDomain        55..1392
                     /aSDomain="CAL_domain"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg6_1_CAL_domain.1"
                     /evalue="7.60E-139"
                     /label="ctg6_1_CAL_domain.1"
                     /locus_tag="ctg6_1"
                     /protein_end="464"
                     /protein_start="18"
                     /score="455.2"
                     /specificity="Minowa: NH2"
                     /tool="antismash"
                     /translation="TYQQLEQKAKALAAQLQLQMSPGERALLLYPSEEEFIIAFFACLY
                     AGVIAVPVYPPRRNQKLSRLQAITKDAQAKLALTTTSLLSTIEEKFSSDPELVTVPCLA
                     TNNIPDKQAENWQKPNLSLEDIAFLQYTSGSTGMPKGVMVSHKNLLHNEKLIASAFGHT
                     SETIGVGWLPLFHDMGLIGNVLQPVYVGFPCVIMPPEAFIQKPLRWLQAISRYNATSSG
                     GPNFAYELCADKINPQERENLDLSCWDVAFTGAEPVRAATLEKFANTFADYGFKREAFY
                     PCYGMAETTLFVSGGIKNQSPVIAAVDKLALLENSAVTINSQHPNAQLLVGCGHAWLSE
                     KIVIVNPESLTECRDGEIGEIWVSSDSVAQGYWNRPEQTAETFKAYLADTQVGPFLRTG
                     DLGFLLAGELFITGRLKDLIIVQGRNHYPQDIESTVEKSYPGLRQGCG"
     aSModule        55..2010
                     /domains="nrpspksdomains_ctg6_1_CAL_domain.1"
                     /domains="nrpspksdomains_ctg6_1_ACP.1"
                     /incomplete
                     /locus_tags="ctg6_1"
                     /starter_module
                     /tool="antismash"
                     /type="unknown"
     CDS_motif       433..492
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg6_1_0002"
                     /evalue="4.40E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg6_1"
                     /protein_end="164"
                     /protein_start="144"
                     /score="28.4"
                     /tool="antismash"
                     /translation="AFLQYTSGSTGMPKGVMVSHK"
     CDS_motif       526..552
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg6_1_0003"
                     /evalue="9.90E+01"
                     /label="PKSI-KS_m6"
                     /locus_tag="ctg6_1"
                     /protein_end="184"
                     /protein_start="175"
                     /score="-3.6"
                     /tool="antismash"
                     /translation="SAFGHTSETI"
     CDS_motif       1117..1203
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg6_1_0004"
                     /evalue="2.60E-13"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg6_1"
                     /protein_end="401"
                     /protein_start="372"
                     /score="42.1"
                     /tool="antismash"
                     /translation="DGEIGEIWVSSDSVAQGYWNRPEQTAETFK"
     CDS_motif       1288..1350
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg6_1_0005"
                     /evalue="1.60E-03"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg6_1"
                     /protein_end="450"
                     /protein_start="429"
                     /score="11.3"
                     /tool="antismash"
                     /translation="TGRLKDLIIVQGRNHYPQDIES"
     aSDomain        1807..2010
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg6_1_ACP.1"
                     /evalue="5.00E-17"
                     /label="ctg6_1_ACP.1"
                     /locus_tag="ctg6_1"
                     /protein_end="670"
                     /protein_start="602"
                     /score="53.8"
                     /tool="antismash"
                     /translation="EWLIKKVAEILQIAPEKIDIQQDLASYGLSSLAAVSLSGELEQWL
                     GKSVSPMLVYEYPSIHAVARYLAL"
     aSDomain        2095..3339
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg6_1_PKS_KS.1"
                     /evalue="4.80E-191"
                     /label="ctg6_1_PKS_KS.1"
                     /locus_tag="ctg6_1"
                     /protein_end="1113"
                     /protein_start="698"
                     /score="626.9"
                     /tool="antismash"
                     /translation="IAIIGIGCRFPKAKDPETFWQLLRQGVDGITEVSSQRWNYQDFGH
                     LNTRWGGFLENVYDFEPQFFGIAPREAVDMDPQQRLLLEVSWEALENACIAPETLAGSQ
                     TGVFIGISTNDHARLLSQDNESIDAYYGTGNAFCVAANRLSYFLDFHGPSLAIDTACSS
                     SLVAVHEACKSLTDGECHLALAAGVNLLLSPQLTINFSKAGMLASDGHCKTFDESADGY
                     VRGEGCGVVILKRLEDAIKDGDRIYAIIRGSAVNQDGHSNGLTAPNKQAQKAVIKKALA
                     KAQVSAKDISYVEAHGTGTSLGDPIELNTLKEVLMQDRQLSNPCWIGSVKTNIGHLEAA
                     AGIAALIKVCLALQNREIPPHLHLQKLNPYISLEGTSLSIPTQLQPWKKGKKGRLAGVS
                     SFGFGGTNAHVILEEFV"
     aSModule        2095..3339
                     /domains="nrpspksdomains_ctg6_1_PKS_KS.1"
                     /incomplete
                     /locus_tags="ctg6_1"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       2548..2595
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg6_1_0006"
                     /evalue="7.40E-07"
                     /label="PKSI-KS_m3"
                     /locus_tag="ctg6_1"
                     /protein_end="865"
                     /protein_start="849"
                     /score="21.0"
                     /tool="antismash"
                     /translation="GPSLAIDTACSSSLVAV"
     CDS_motif       2737..2775
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg6_1_0007"
                     /evalue="4.50E-05"
                     /label="PKSI-KS_m4"
                     /locus_tag="ctg6_1"
                     /protein_end="925"
                     /protein_start="912"
                     /score="16.3"
                     /tool="antismash"
                     /translation="FDESADGYVRGEGC"
     CDS_motif       2968..3015
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg6_1_0008"
                     /evalue="7.60E-05"
                     /label="PKSI-KS_m5"
                     /locus_tag="ctg6_1"
                     /protein_end="1005"
                     /protein_start="989"
                     /score="14.5"
                     /tool="antismash"
                     /translation="YVEAHGTGTSLGDPIEL"
     CDS_motif       3076..3120
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg6_1_0009"
                     /evalue="2.00E-04"
                     /label="PKSI-KS_m6"
                     /locus_tag="ctg6_1"
                     /protein_end="1040"
                     /protein_start="1025"
                     /score="13.5"
                     /tool="antismash"
                     /translation="GSVKTNIGHLEAAAGI"
     CDS_motif       3658..3705
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg6_1_0010"
                     /evalue="8.90E-07"
                     /label="PKSI-AT-M_m1"
                     /locus_tag="ctg6_1"
                     /protein_end="1235"
                     /protein_start="1219"
                     /score="21.1"
                     /tool="antismash"
                     /translation="FTGQGSQYINMARELYE"
ORIGIN
        1 gagcaaacag cttatatctt tttggctaat ggagaaacag aaaccgccag actaacttat
       61 cagcaattag agcaaaaagc aaaagctttg gcggctcaac ttcagttaca aatgtctccg
      121 ggagaaagag ctttattgct ctatccatcg gaggaagaat ttatcattgc tttctttgcc
      181 tgtttatatg cgggtgttat tgccgttccc gtttatcctc cccgacgtaa tcaaaagctc
      241 tctcgactac aagcaataac taaagatgct caagccaaac tggccttaac tactacatcc
      301 ttattaagta ctattgagga aaaattttcg agtgaccctg agttagtaac agtaccttgc
      361 ctagctacta ataacatccc ggataagcaa gcagaaaact ggcaaaaacc gaatctttct
      421 ttagaggaca tagctttcct acaatatact tccggttcca caggtatgcc taagggagtt
      481 atggttagtc ataaaaattt acttcataat gaaaaactga ttgcttctgc ctttggacat
      541 acaagcgaaa ctattggtgt gggatggttg ccactatttc atgatatggg actaattggt
      601 aacgtattac aaccagtgta cgtcggattt ccttgtgtga ttatgcctcc agaagcattt
      661 atccaaaaac cgctccgatg gttacaggct atttctcgct acaacgctac cagtagtggc
      721 ggtcctaatt ttgcttacga attatgtgct gataaaatta accctcaaga gcgagaaaat
      781 ctggatttaa gttgttggga tgtagctttt actggagccg aacctgtgcg agcagctacc
      841 ttagaaaaat ttgctaatac tttcgctgat tatggtttta agagagaggc attttatcct
      901 tgttatggga tggctgaaac tactctattt gtgtcggggg gaattaaaaa tcaatctccc
      961 gtgattgcag cagttgataa attagctctt ttagaaaata gtgccgttac tattaactct
     1021 caacacccga atgctcaatt attagttggt tgtggtcacg cttggttatc agaaaaaatt
     1081 gtaattgtga atcctgaatc tttaactgaa tgtcgagatg gggaaatagg agaaatttgg
     1141 gtatctagtg atagtgtagc tcagggttat tggaatcgac ccgaacagac agcagaaact
     1201 ttcaaagctt atttagctga tacccaggtt gggccatttc tgcggacagg agatttagga
     1261 tttttactgg ctggtgagtt atttatcaca ggaagactca aggatttaat tattgtgcaa
     1321 ggacgtaatc attatcctca agatattgaa tccaccgtcg aaaaaagtta cccgggattg
     1381 cggcaagggt gtggagcagt attttcagtg gaaattgctg gtcaagaaag gctagtagtt
     1441 gttcaagaag tcgaacgaag ctatctgcgt aaattagact caccagcggt aattgagcaa
     1501 attattcgct ctgttgccga agaacatcaa ctagatgttt atgccgtggc actgctgaaa
     1561 acagcaagta ttcccaagac atctagtggc aagattcaac gtcaagcttg ccgagctagt
     1621 ttcctagcag gaactcttaa tgtgattggg gattggagta agaatcctga acataagaat
     1681 ggatttaagc agcttaaatc agatattaac tctctgctaa aacaagtcaa aagttatcag
     1741 gttgttgaag aattctctga ggtcagtcag aatcaaattg tgtccgatac tcaagaagca
     1801 attgaagagt ggctaattaa aaaagttgca gagatcttgc aaatagcacc agaaaaaata
     1861 gatattcaac aagacttagc aagttatgga ctgagttctt tagcggcagt aagtctttcg
     1921 ggagagcttg agcaatggct cggaaaaagt gtatctccca tgctggttta tgaatatcct
     1981 agcattcatg cagttgctcg ctatttagcc ctaaatggat taagttctga agctctagct
     2041 acaacttcat ccacagtcgc tcaaaaaacc tcatcacaac ctcaaaatga accgatcgct
     2101 attatcggta ttggctgtcg ttttcccaaa gctaaagatc cagaaacatt ctggcaacta
     2161 ttacgccaag gagtagacgg aataacagaa gtatcttctc aaagatggaa ttaccaagat
     2221 tttgggcatc taaacaccag atggggggga tttttagaga atgtttatga ttttgaacct
     2281 cagttttttg gtattgcacc tcgggaagca gtggatatgg atccccagca aagacttctg
     2341 ttagaagtca gttgggaagc tctcgaaaat gcttgtattg cccccgaaac tttagcaggg
     2401 agtcaaacag gtgtatttat tggcatcagc actaatgatc atgctcgctt gttatctcaa
     2461 gataatgagt ctatagatgc ttactatggt acaggtaacg ctttttgcgt ggccgctaat
     2521 cgtttatcct atttcctcga tttccatgga cctagtttag ctatagatac ggcctgttct
     2581 tcctcgttag ttgctgtcca tgaagcttgt aagagcttaa ccgatgggga atgtcatctc
     2641 gcattagcag ccggggtaaa tttgctccta tctccccaat taaccattaa tttctcaaaa
     2701 gcagggatgt tagcgtctga tggtcactgt aaaacctttg atgaaagtgc tgatgggtat
     2761 gtcaggggtg aaggttgtgg ggtagttatc ctcaaacgtc tagaggatgc tattaaagac
     2821 ggcgatcgca tttatgcaat tattcgcggt tcagcagtta atcaagatgg tcacagtaat
     2881 ggactaactg cacccaataa acaagctcaa aaagctgtta ttaaaaaagc cttagccaaa
     2941 gctcaggtaa gcgccaaaga tattagctac gtggaagctc atggtacggg aacatcttta
     3001 ggggatccca ttgagcttaa tactcttaaa gaagtattaa tgcaagatcg tcaactatcg
     3061 aacccctgtt ggattggttc tgtaaaaact aatattggtc atctcgaagc agccgcagga
     3121 attgccgcac tgattaaagt ttgcctcgct ttacaaaatc gtgaaattcc tcctcacctt
     3181 catttgcaaa aactcaatcc ttatatttct ctagaaggaa cttccttatc tattcctact
     3241 caattacagc cttggaaaaa gggtaaaaaa gggcgattag ctggggtatc ttcttttggt
     3301 tttggtggca ctaatgctca tgttatttta gaagaatttg ttccagaaac cttggagcaa
     3361 gagcaacatg aaccatctct tgctatcttg actattaccg ctaaaactaa gtcatctttg
     3421 cgagaattag tatcaagtta tcacaattat cttcaagcaa atccgcaaat caacttacaa
     3481 gacttttgct ttagtgctga tgtggggcgc tcgcattttc atcattgttt agctattcaa
     3541 actgagtctt taactcaatt acaatcccag ttagaggcta ttattgaggg caaagaagct
     3601 gggggaattt tgaccggtga actatcgcac cagaagcacc agaaaattgc gtttcttttt
     3661 acaggtcagg ggtcacaata tatcaatatg gcccgggaac tttatgagac tcaacctact
     3721 ttccgtagaa cccttgaaca ctgtcaagag attcttagta tctatttaga caaacctttg
     3781 ctatctattc tctatcctca agagggagag aactcacc
//
