LOCUS       c00513_3300013..        7252 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300013122.a:Ga0172374_1005401.
ACCESSION   c00513_3300013..
VERSION     c00513_3300013..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 12:21:55
            Original ID  :: 3300013122.a:Ga0172374_1005401
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 7252
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..7252
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2:3490]"
                     /cutoff="20000"
                     /detection_rule="(APE_KS1 or APE_KS2)"
                     /neighbourhood="20000"
                     /product="arylpolyene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3..3490
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(APE_KS1 or APE_KS2)"
                     /neighbourhood="20000"
                     /product="arylpolyene"
                     /protocluster_number="1"
     cand_cluster    1..7252
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(APE_KS1 or APE_KS2)"
                     /kind="single"
                     /product="arylpolyene"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..7252
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="arylpolyene"
                     /region_number="1"
                     /rules="(APE_KS1 or APE_KS2)"
                     /tool="antismash"
     CDS             3..1067
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (50-353). E-value:
                     1.1e-29. Score: 95.3. Matches aSDomain:
                     nrpspksdomains_ctg513_1_PKS_KS.1"
                     /NRPS_PKS="type: PKS/NRPS-like protein"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     arylpolyene: APE_KS2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 193.3; E-value:
                     1.2e-58)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg513_1"
                     /sec_met_domain="APE_KS2 (E-value: 6e-145, bitscore: 472.6,
                     seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="DRSLTVGAVHVDLPAMPAGFESSHSRNNQLLLAAAQQIEPELRAA
                     ITRFGAQRVGLVLGTSTSGIREAGEHIAHHLNEGALPAEYNYAQQEMAAPANFLADWLG
                     LSGPVYCQSTACTSSARAMLSAHRLLSQGLCDAVICGGVDSLCRLTLNGFSSLEAVCAE
                     PCNPFSVNRHGINIGEAAALFLMTREYGPIAFFGGGATSDAYHISAPHPEGLGARAAME
                     KALANAGIAASEIDYLNLHGTATRHNDVMESKAVHALFPAGLPCSSSKPMTGHTLGAAG
                     ALEAAFCWLTLSEYNRDGLLPPHLWDGQHDPELAPLELVQPGARLARNQGRYLMSNSFA
                     FGGNNVALILGDAS"
     aSDomain        153..1061
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg513_1_PKS_KS.1"
                     /evalue="1.10E-29"
                     /label="ctg513_1_PKS_KS.1"
                     /locus_tag="ctg513_1"
                     /protein_end="353"
                     /protein_start="50"
                     /score="95.3"
                     /tool="antismash"
                     /translation="AQRVGLVLGTSTSGIREAGEHIAHHLNEGALPAEYNYAQQEMAAP
                     ANFLADWLGLSGPVYCQSTACTSSARAMLSAHRLLSQGLCDAVICGGVDSLCRLTLNGF
                     SSLEAVCAEPCNPFSVNRHGINIGEAAALFLMTREYGPIAFFGGGATSDAYHISAPHPE
                     GLGARAAMEKALANAGIAASEIDYLNLHGTATRHNDVMESKAVHALFPAGLPCSSSKPM
                     TGHTLGAAGALEAAFCWLTLSEYNRDGLLPPHLWDGQHDPELAPLELVQPGARLARNQG
                     RYLMSNSFAFGGNNVALILGDAS"
     aSModule        153..1061
                     /domains="nrpspksdomains_ctg513_1_PKS_KS.1"
                     /incomplete
                     /iterative
                     /locus_tags="ctg513_1"
                     /tool="antismash"
                     /type="pks"
     CDS             1064..1528
                     /locus_tag="ctg513_2"
                     /transl_table=11
                     /translation="MSLWPVAELVPHAGNMVLLDEVLSCDSEAIEARLVVRPDGLLSDA
                     DGNLPAWTGIELMAQAIAAFAGVQAKRAGLPVELGFLLGTRKYACNVERFPAGSELRIR
                     ALCSLQDDNGMGVFECHLQGPGIQAEARLNVFRPPQPAVYLQEPQEQSHD"
     CDS             1521..2264
                     /NRPS_PKS="Domain: PKS_KR (8-169). E-value: 9.9e-26. Score:
                     82.5. Matches aSDomain: nrpspksdomains_ctg513_3_PKS_KR.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     230; E-value: 5e-70)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg513_3"
                     /sec_met_domain="adh_short (E-value: 1.6e-42, bitscore:
                     135.0, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTESTSAPTVLVTGSSRGIGRAIALRLARSGHDIVLHCRSRRDEA
                     ETVQAQITELGRQARILQFDVSDRAACREALEADVEQHGAYYGVVCNAGLTRDGAFPAL
                     SEEDWDQVLRTNLDGFYNVLHPLTMPMIRRRAPGRIVCITSVSGLVGNRGQVNYSASKA
                     GVIGAAKALAIELAKRKITVNCVAPGLIDTEILDELVPVDEILKMVPAARMGTPEEVAG
                     AVNFLMSDEAAYITRQVLAVNGGLC"
     CDS_motif       1545..1616
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg513_3_0001"
                     /evalue="2.60E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="ctg513_3"
                     /protein_end="32"
                     /protein_start="8"
                     /score="16.9"
                     /tool="antismash"
                     /translation="TVLVTGSSRGIGRAIALRLARSGHD"
     aSDomain        1545..2027
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg513_3_PKS_KR.1"
                     /evalue="9.90E-26"
                     /label="ctg513_3_PKS_KR.1"
                     /locus_tag="ctg513_3"
                     /protein_end="169"
                     /protein_start="8"
                     /score="82.5"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="TVLVTGSSRGIGRAIALRLARSGHDIVLHCRSRRDEAETVQAQIT
                     ELGRQARILQFDVSDRAACREALEADVEQHGAYYGVVCNAGLTRDGAFPALSEEDWDQV
                     LRTNLDGFYNVLHPLTMPMIRRRAPGRIVCITSVSGLVGNRGQVNYSASKAGVIGAAK"
     aSModule        1545..2027
                     /domains="nrpspksdomains_ctg513_3_PKS_KR.1"
                     /incomplete
                     /locus_tags="ctg513_3"
                     /tool="antismash"
                     /type="unknown"
     CDS_motif       1941..2000
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg513_3_0002"
                     /evalue="2.70E-07"
                     /label="PKSI-KR_m4"
                     /locus_tag="ctg513_3"
                     /protein_end="160"
                     /protein_start="140"
                     /score="23.1"
                     /tool="antismash"
                     /translation="VCITSVSGLVGNRGQVNYSAS"
     CDS             2264..3490
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (62-406). E-value:
                     2.9e-44. Score: 143.3. Matches aSDomain:
                     nrpspksdomains_ctg513_4_PKS_KS.1"
                     /NRPS_PKS="type: PKS/NRPS-like protein"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     arylpolyene: APE_KS1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 312.8; E-value:
                     6.1e-95)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg513_4"
                     /sec_met_domain="APE_KS1 (E-value: 7.6e-204, bitscore:
                     666.4, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRVVVTGMAGITSLGSDWPTISAAFKAGKSGIRRMDEWDRFTEL
                     NTRLGGPVDDFVQPKHWNRKQTRSMGRVSKLAVYAAERALEHAGLLGDPCIADGRMGVA
                     CGSSTGSTEEVKAFGNMLLNSVADGLNANSYIRMMPHTTAANISIFFGLKGRLIPTSSA
                     CTSGSQGIGYAYEAIKFGRLKMMLAGGAEELCPTEAMVFDALYATSLKNDAPHTSPRPY
                     DSGRDGLVIGEGAGILVLEELEHALARGATIHAEIVGFGCNSDGQHATKPVQETMRGAM
                     QLALDDAGLEPSAIGYVNGHGTATEQGDVAETLATSSLFGAQMPISSQKSYLGHTLGAC
                     GALESWFSIEMMNSDSYVYTLNLDEIDPACGELDYLRGEFRQMSHEYVMNNNFAFGGVN
                     TSLIFKRWQ"
     aSDomain        2450..3481
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg513_4_PKS_KS.1"
                     /evalue="2.90E-44"
                     /label="ctg513_4_PKS_KS.1"
                     /locus_tag="ctg513_4"
                     /protein_end="406"
                     /protein_start="62"
                     /score="143.3"
                     /tool="antismash"
                     /translation="NRKQTRSMGRVSKLAVYAAERALEHAGLLGDPCIADGRMGVACGS
                     STGSTEEVKAFGNMLLNSVADGLNANSYIRMMPHTTAANISIFFGLKGRLIPTSSACTS
                     GSQGIGYAYEAIKFGRLKMMLAGGAEELCPTEAMVFDALYATSLKNDAPHTSPRPYDSG
                     RDGLVIGEGAGILVLEELEHALARGATIHAEIVGFGCNSDGQHATKPVQETMRGAMQLA
                     LDDAGLEPSAIGYVNGHGTATEQGDVAETLATSSLFGAQMPISSQKSYLGHTLGACGAL
                     ESWFSIEMMNSDSYVYTLNLDEIDPACGELDYLRGEFRQMSHEYVMNNNFAFGGVNTSL
                     IFKRW"
     aSModule        2450..3481
                     /domains="nrpspksdomains_ctg513_4_PKS_KS.1"
                     /incomplete
                     /iterative
                     /locus_tags="ctg513_4"
                     /tool="antismash"
                     /type="pks"
     CDS             3514..3906
                     /locus_tag="ctg513_5"
                     /transl_table=11
                     /translation="MMSRFTRFALIVALLLGVAACTSKPVMNIENRTPTSAARNEDDMR
                     RAILAALQSRQWTVERADRGNIMALIQRRSHQAEITIPYSASSYSIRYRDSQNLGYKDG
                     KIHRNYNKWIHNLDRSIQQELNRASF"
     CDS             4008..4448
                     /locus_tag="ctg513_6"
                     /transl_table=11
                     /translation="MQAKIWSTAALLSVALLPGLSQARDTAHFLDFQSVVNEATQAGRL
                     DGSVKFYLNKTPAGAQIINANVTTSQKTNAFNKSDEEACSWVLQSALIKLQNAAKAAGA
                     NAVVDLASNYKNKEYRDDSKYECHAGAIMAGVALKAKYAKVK"
     CDS             4514..5107
                     /locus_tag="ctg513_7"
                     /transl_table=11
                     /translation="MSKLRIALLLLATVTLLGGCTATRVTPLKAAADQMCIEENPKVQV
                     NDFVPVLQEGFARHGIQTQIYSQIPRADCPYVVTYTARRSWDMAPYLSTAEITILGPRR
                     QTLAKANYHLRGKGGLSLMKWQGTKSKIDPVIDELLASAQLSSAAPPPAQTHSTAEPRK
                     SLDERVRDLQQQKLGYEDYQRAYRQLLLEHQSGQ"
     CDS             complement(5128..5682)
                     /locus_tag="ctg513_8"
                     /transl_table=11
                     /translation="VTIWQLVAFVVLSALLVGISWRTLGNPRSHGFYRFLAWEVMALML
                     VLNAPFWFGDRGELHQRISWVLLSLSLAVLFAGVYQMRRFGQAGEQRQDDELFAFERTS
                     QLVTGGIFRYIRHPMYCSLLLLAWGIAFKRIDMLIVLLAVLSSVLLWCAARCEERECLA
                     YFGEAYREYMGRSWMFLPLVL"
     CDS             5745..6149
                     /locus_tag="ctg513_9"
                     /transl_table=11
                     /translation="MDRTQLHTLLPHQGDALWLDALVDHDSLNIRGLSAWHHLDKLGEN
                     ASPCLLFEAAAQLCAAHGALYGEADAIEMALVGKLSQLNLHPVTRSAEPLLVSAQQEAL
                     SPAGALYAFTIQAGNQPLLDGKLLLVLVRA"
     CDS             6142..7026
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 167.6; E-value:
                     5.9e-51)"
                     /gene_kind="transport"
                     /locus_tag="ctg513_10"
                     /transl_table=11
                     /translation="VLELRDVSFRYPGADASALQGIDLQLEEGQCLGLLGSNGAGKTTL
                     LALLSDTLALQQGEVRWHGPRSLGLVPQQLAFYAELTVAENLALFADLYRLHGAQRRQR
                     LELCIASCALEDKLPRRAARLSGGEQRRLNFAIGLLQPARLYLFDEATVGVDAGSRQLL
                     LDAVERLAAQGHGVIYTSHYLDEVERVAGRILLLHEGKVRLDVDKQQLLDGGHGLLLEW
                     PEQVPAGFQQLLDQLQLSAEMLPDGLRIGNLDSQQLLAITQFLATQPSPPSLLRFGRPS
                     LEQLYLSLNGGRL"
     CDS             7023..7250
                     /locus_tag="ctg513_11"
                     /transl_table=11
                     /translation="VTPLLALVRKECLLLLRDPHALAVLFIMPILFLVLMAAALSNYLS
                     DQPPPLNLVLKAPQHSEASAFFQQALQEQLP"
ORIGIN
        1 acgaccgcag cctgacggta ggcgccgtgc acgtcgatct gcccgccatg cctgcaggtt
       61 tcgagagctc gcacagccgc aacaaccagt tgctgctggc cgctgcgcaa cagatcgaac
      121 ccgagctgcg cgcagccatc acccgtttcg gcgcgcagcg cgtcggcctg gtgctgggca
      181 ccagcacctc gggcatccgc gaagcgggcg agcatatcgc gcaccatctc aacgaaggcg
      241 cgctgcccgc cgaatacaac tacgcccaac aggaaatggc cgcaccggcc aacttcctcg
      301 ccgactggct gggcctgagc ggcccggtgt actgtcagtc cacggcctgc acctccagcg
      361 cccgtgccat gctcagcgct catcgcctgc tcagtcaggg tctctgcgat gcagtgatct
      421 gcggtggcgt cgacagcctg tgtcgcctca ccctgaatgg cttttcgtcg ctggaagccg
      481 tctgcgccga accctgcaat ccgttctcgg tgaaccgcca cggcatcaat atcggtgagg
      541 cggcggcgtt gtttctgatg acccgcgagt acggccccat cgccttcttc ggtggtggcg
      601 ccacctccga cgcctaccat atctccgcac cgcacccgga aggcctcggt gcccgtgccg
      661 ccatggagaa ggcgctggcc aacgccggca tcgccgccag tgaaatcgac tatctcaacc
      721 tgcatggcac cgctacccga cataacgacg tgatggagag caaggccgtg cacgccctgt
      781 tccctgcggg tctgccttgc tcctcgagca aacccatgac cggccacacc ctaggcgccg
      841 ccggcgcgct ggaagcggcc ttctgctggc tgaccctgag cgaatacaac cgtgacggcc
      901 tgctgccacc gcacctctgg gatggccagc acgaccccga actggcgccc ctcgagctcg
      961 tccagcctgg cgcccgcctg gcccgtaacc agggccgtta cctgatgagc aactccttcg
     1021 ccttcggcgg caataacgtt gcgctgatcc tgggagatgc ctcatgagcc tgtggcccgt
     1081 cgccgaactg gtgccccacg cgggcaacat ggtgctgctc gatgaagtat tgagctgcga
     1141 tagcgaagcg atcgaggcac gcctcgtcgt acgcccggac ggcctgctca gcgatgctga
     1201 cggcaacctg ccggcctgga ccggcatcga gctgatggcg caggccatcg ccgctttcgc
     1261 cggcgtccag gccaagcgcg ccggcctgcc ggtggagctg ggtttcctgc ttggcacgcg
     1321 caaatacgcc tgtaacgtcg agcggttccc ggccggcagc gaattgcgca tacgcgccct
     1381 gtgctcactg caggacgata acggcatggg cgtgttcgaa tgccacctgc aaggccccgg
     1441 catccaggcc gaagcccgcc tcaacgtgtt ccgcccgccg caaccggcgg tctatttaca
     1501 agaaccgcaa gaacaatccc atgactgaaa gcacctccgc ccccaccgtt ctggtcaccg
     1561 gctccagccg tggcatcggc cgcgccatcg ccctgcgcct ggcacgctcg ggccatgaca
     1621 tcgtcctgca ctgccgttcg cgccgcgatg aggccgaaac cgtgcaggcg caaatcaccg
     1681 agctgggtcg ccaggcgcgc atcctgcaat tcgacgtgtc cgatcgcgcc gcctgccgcg
     1741 aggcgctgga ggccgatgtc gagcagcacg gcgcctacta cggcgtagtg tgcaacgccg
     1801 gcctgacccg cgacggcgcc ttcccggcgc tgtccgagga ggactgggat caggtgctgc
     1861 gcaccaatct ggatggtttc tacaacgtgc tgcacccgct gaccatgccg atgatccgcc
     1921 gccgcgcgcc aggtcgtatc gtctgcatca cctcggtgtc gggtctggtc ggcaaccgtg
     1981 gccaggtcaa ctacagcgcg tccaaggccg gcgtgatcgg cgccgccaag gccctggcga
     2041 tcgaactggc caagcgcaag atcaccgtca actgcgtggc gcccggcctg atcgacaccg
     2101 agattctcga cgagctggtg ccggtggacg agattctcaa gatggtcccg gccgcccgta
     2161 tgggcacccc cgaagaagtg gccggtgcgg tgaactttct gatgtccgac gaggcggcgt
     2221 acattacgcg ccaggttctc gcggtgaatg gtggtttgtg ttgatgaaac gtgtagtcgt
     2281 caccggcatg gccggtatca cctcgctggg cagcgactgg ccaaccatct cggccgcatt
     2341 caaggccggc aagagtggta tccggcgcat ggacgaatgg gaccgtttca ccgagctgaa
     2401 cacccgtctg ggtgggccgg tggacgattt cgtccagccc aagcactgga accgcaagca
     2461 gacgcgcagc atgggccggg tgtccaagct ggccgtgtat gccgccgaac gcgccctgga
     2521 gcacgccggc ctgctcggcg acccgtgcat cgctgacggg cgcatgggtg tagcctgcgg
     2581 ctcgtccacc ggcagcaccg aggaggtcaa ggccttcggc aacatgctgc tgaactcggt
     2641 ggcggacggc ctcaatgcca actcctacat ccgcatgatg ccgcacacca cggcggccaa
     2701 catcagcatc ttcttcggtc tcaagggtcg cctgatcccc acgtccagcg cctgcaccag
     2761 tggcagccag ggcatcggct acgcctacga ggcgatcaag ttcggtcgcc tgaagatgat
     2821 gctcgccggt ggcgccgagg agctgtgccc gaccgaagcc atggtcttcg acgcgctgta
     2881 cgccaccagc ctgaagaacg acgcgccaca caccagcccg cgcccctacg acagcggccg
     2941 tgacggcctg gtaatcggtg aaggcgccgg catcctggtg ctcgaagagt tggagcacgc
     3001 cctcgcccgc ggtgccacca tccatgccga gatcgtcggt ttcggctgca actccgacgg
     3061 tcagcacgcc accaagccgg tgcaggaaac catgcgcggc gccatgcagc tggcactcga
     3121 tgacgccggc ctggaaccct cggcaatcgg ttacgtcaac ggccatggca ccgctaccga
     3181 acagggcgac gtcgccgaga ccctggccac cagcagcctg ttcggcgcgc agatgccgat
     3241 aagctcgcag aagagctacc tcggccatac cctgggcgcc tgcggggcgc tggagtcctg
     3301 gttcagcatc gagatgatga attcggacag ctacgtctac accctgaacc tggacgaaat
     3361 cgacccggcc tgcggtgaac tggattatct gcgcggcgag ttccgccaga tgagccatga
     3421 atacgtgatg aacaacaact tcgcctttgg tggcgtgaac acctcgctga tcttcaaacg
     3481 ctggcaatga ccttcaactg acaaggaaca tggatgatgt ctcgtttcac tcgatttgct
     3541 ctgatcgttg cgttgctgct gggcgtcgca gcctgtacgt cgaagccggt gatgaacatt
     3601 gagaaccgca cacccacttc ggcggccagg aatgaggatg atatgcgcag ggccattctc
     3661 gccgcgctgc aaagccgcca gtggacggtc gagcgtgccg accggggcaa catcatggcg
     3721 ttgattcagc gacgcagtca ccaggccgag atcaccattc cctacagcgc gtcgagctat
     3781 tcgatccgct accgcgacag ccagaacctt ggctacaaag acggcaagat ccatcgcaac
     3841 tacaacaagt ggatccataa tctggatcgc agcatccagc aggaactgaa cagggcgtcc
     3901 ttctagcagg tgcctggttg gtaacggcct gttcatcagt gctacaggcc caagcgcagc
     3961 agacgttgaa cgagctttta catacattga tattcaagga gataaccatg caagcaaaaa
     4021 tctggagcac tgccgcactt ctctccgtcg ccctgctgcc cggcctcagc caggcgcgcg
     4081 acaccgctca cttcctcgac ttccagtcgg tggtcaacga agccacccag gctggtcgtc
     4141 tcgacggttc agtgaagttc tacctgaaca agaccccggc tggtgctcag atcatcaacg
     4201 ccaacgtcac caccagccag aagaccaacg ccttcaacaa gagcgatgag gaagcctgca
     4261 gctgggttct gcaatcggcc ctgatcaagt tgcagaacgc tgccaaggcc gccggagcca
     4321 acgcagtggt cgacctggcc agcaactaca agaacaagga ataccgtgac gacagcaaat
     4381 acgaatgcca tgccggcgcc atcatggccg gtgtcgcgct gaaggccaaa tacgccaagg
     4441 tgaagtgaca ccagcggcac tcacgcaaag gccaccgtcg aggtggcctt ctcacgcaag
     4501 gaagccctct cccatgtcga aactacgcat tgcactgctc ttgctcgcaa cggtaaccct
     4561 actaggcggt tgcactgcta cccgggtcac gccactaaag gcggcggccg accagatgtg
     4621 tatcgaagag aacccaaaag ttcaggtcaa cgacttcgtg cccgtactgc aggaaggctt
     4681 cgcacggcat ggaatccaga cgcagatcta ctcgcagatt cccagagcag actgccctta
     4741 cgtggtgact tacaccgccc gccgctcctg ggacatggcg ccgtacctat ccaccgccga
     4801 aatcaccatc ctcggcccgc ggcgccagac actggctaaa gccaactatc acctgcgcgg
     4861 caagggcggc ctgtcgctga tgaaatggca aggcaccaaa agcaagatag acccggtcat
     4921 cgacgagctg ctggccagcg cacagttgag cagcgcagcc ccacctcccg cacagaccca
     4981 ctcgacagcc gagccacgca agagcctgga tgaacgcgtg cgtgatctgc agcagcaaaa
     5041 gctcggctat gaggattatc aacgcgccta tcggcagctt ctgctggagc accagagcgg
     5101 acaatagagc cgctgagcgc tgagatctca gagcacgagt ggcaagaaca tccaactgcg
     5161 ccccatatac tcgcggtagg cctcgccgaa ataggccagg cactcgcgct cctcacaacg
     5221 cgcggcacac cacagcagca cgctggagag cactgccagc aacacgatca gcatatcgat
     5281 acgcttgaaa gcgatgcccc aggccagcag cagcaacgag cagtacatgg ggtgccggat
     5341 gtagcggaag atgccgcccg tcaccagttg tgacgtgcgt tcgaaagcaa atagctcatc
     5401 atcctggcgc tgctcaccgg cctgaccaaa acggcgcatc tggtacacgc cagcgaacag
     5461 cactgccagc gaaagactca gcagcaccca ggatatgcgc tgatgcagtt caccccggtc
     5521 gccgaaccag aacggcgcat tgagtaccag catcagcgcc atcacctccc acgcaagaaa
     5581 acgatagaac ccgtgactgc gtggattgcc cagggtgcgc caggaaattc ccaccagcaa
     5641 tgcgctgagc accacaaaag ccaccaactg ccagatcgtc actgcatcct ccctctatcc
     5701 ctgctctgat acactgcgtc gcccgtatgc accgaccgac cgccatggat cgcacccaac
     5761 tgcacacact gctgccgcac cagggcgacg cgctctggct ggatgcattg gtcgatcatg
     5821 acagcctcaa tatccgcgga ctcagcgcct ggcatcatct cgacaagctt ggcgaaaatg
     5881 cctcgccttg cctgctgttc gaagccgccg cccaactttg cgccgcacat ggtgccctat
     5941 acggcgaagc ggatgccatt gaaatggccc tagtcggcaa actttcccag ctcaatctgc
     6001 acccggtcac acgcagtgca gagccgctac tggtcagcgc ccagcaggag gcgttgagcc
     6061 ccgccggtgc gctctacgcc ttcaccatcc aggccggcaa ccaaccgctg ctggacggca
     6121 aactgctgct ggtactcgtc cgtgcttgag ttacgtgacg tcagttttcg ctacccaggc
     6181 gcagacgctt cggctctgca aggcatcgat ctgcagctag aagaaggcca gtgcctgggc
     6241 ctgctcggca gcaacggcgc cggcaagacc accttgctcg cgctactcag cgataccctc
     6301 gccctgcaac agggcgaggt tcgctggcac ggcccgcgca gcctgggtct ggtgccgcag
     6361 caactggcgt tctacgccga actgacggtg gcagaaaacc tcgcgctgtt cgccgatctg
     6421 taccgcctgc acggcgccca gcgccgccag cgcctggagc tgtgcatcgc cagctgcgcc
     6481 ctcgaagaca agctgccgcg ccgcgccgca cgcctgtccg gtggcgagca acgtcgtctg
     6541 aatttcgcca tcggcctttt gcaaccggcg cgtctgtatc tgttcgatga agccacagtc
     6601 ggcgtcgatg ccggcagccg gcaactgctg ctcgatgccg tagaacgact cgctgcgcaa
     6661 ggccatgggg tgatctacac cagccactat ctggacgagg tcgagcgcgt ggctgggcgg
     6721 atcctgcttc tgcatgaagg caaggtacgt ctcgatgtcg acaagcagca actgctcgat
     6781 ggcggccacg gcctgttgct ggaatggcca gagcaggttc ccgccggctt tcagcaactg
     6841 ctcgaccagc tgcaactgag cgccgagatg ctgccggatg gtctgcgcat cggcaacttg
     6901 gatagccaac aattgctggc gatcacccag ttccttgcca cacagccgag cccaccgagc
     6961 ctgctgcgct ttggccggcc ctctttggag cagctctacc tgagcctcaa cggaggccgc
     7021 ctgtgacccc gttgctggcg ctggtacgca aggaatgcct gctgctgctt cgcgacccgc
     7081 atgcgctggc ggtgctgttc atcatgccga tcctgtttct cgtgctgatg gccgccgcgc
     7141 tgtccaacta cctgagcgac cagccgccgc ccctcaacct tgtgctcaag gctccgcagc
     7201 acagcgaggc cagtgccttc ttccagcagg ccttgcagga gcaactgcct gg
//
