LOCUS       c00169_3300013..        6599 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300013131.a:Ga0172373_10022051.
ACCESSION   c00169_3300013..
VERSION     c00169_3300013..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-24 04:21:04
            Original ID  :: 3300013131.a:Ga0172373_10022051
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 6599
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..6599
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2911:6598](+)"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2912..6598
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
     cand_cluster    1..6599
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="single"
                     /product="T1PKS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..6599
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T1PKS"
                     /region_number="1"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /tool="antismash"
     CDS             3..1265
                     /locus_tag="ctg169_1"
                     /transl_table=11
                     /translation="YNLNNLDSIPQVRSLPVELRQAIPVVGSVLPFRTNSYLVNELIDW
                     DNVETDPIYRLNFPCREMLLPDHYKRISALIECGASREKLREAVWKIRHELKPQSVHAL
                     DGTLASLNGRKQQGIVHIYPETVLFFPAEGQMCHAHCTFCFRWLQFVGEEEEIFASMDV
                     NALISYVAQHEEVRDILITGGDPLFMRLDTLSNYVDRILAADIPHLKNIRFGTKTISYW
                     PYRFLTDPGAEALLKLFEKIITKGKHVAVMAHINHPRELATEAAQRAVARIRATGAEIM
                     SQSPLLRHINAAPEIWTELWQEQVRLGIVPYYQFIVRDTGARHYFGVPLVEALEIFRAA
                     YRKVSGLCRTVRGPVMSLPQGKVQVLDVHECAGEKGILLHHIQAPDQNRVLKTFFAVYD
                     ERAQWFTDLKPLRPVDAGFFH"
     CDS             1294..2895
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1053:beta-lactamase (Score: 157.2; E-value: 9.2e-48)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg169_2"
                     /transl_table=11
                     /translation="MQQIRKRTKLLALWTGLILLLSISGCGNTDYISGDVGAPPPVTQK
                     TQAALKAAVDDYMQYVGTPSGVPGTIVAVKMNGYQPWYYAYGSAEIALPNNPGSAFTQK
                     TAMDAGMPFRIASITKMFIAQAVIQLAQEGKIDLDQTVENYLPGALTGKNLANKDKITI
                     NMLLNHTSGLYSYVTSDAGLLHGNLPTAAGTTGLRLLPMDTFVEGLGLTAWSHSYSPQD
                     TILQFANTFSPPLSLVDTITGAIGNPYGSNPYFAPGTDLHYSNTNYYLLGLLIQKIATQ
                     YETDPAKQTVEYQIKRLITDPLKLSDTYLPTTKTFNNPVHVHGYADYFNSEAYRTAMSD
                     NLLKFSACQNNSAWCTGDGILEDFTEIDPSFAWTTGGMISSAKDLLTFAQFVTQTRVQT
                     GQEAGKWINGSPLDNSTTFQYGRGIARINNVMFGHGGQFAGYNVAVYWYAPLDIYFMVM
                     TNKYSYTENDPNDLGGSIVAGADSMYALSVKQTTAAPVDHNRSIINSLITALEQDPNVA
                     KKGATPVRLSSYFLEM"
     CDS             2912..6598
                     /NRPS_PKS="Domain: PKS_AT (6-301). E-value: 1.9e-91. Score:
                     298.3. Matches aSDomain: nrpspksdomains_ctg169_3_PKS_AT.1"
                     /NRPS_PKS="Domain: ACP (381-430). E-value: 2e-16. Score:
                     51.9. Matches aSDomain: nrpspksdomains_ctg169_3_ACP.1"
                     /NRPS_PKS="Domain: PKS_KS(Hybrid-KS) (453-882). E-value:
                     5.7e-178. Score: 583.9. Matches aSDomain:
                     nrpspksdomains_ctg169_3_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (979-1228). E-value: 1.5e-92.
                     Score: 301.8. Matches aSDomain:
                     nrpspksdomains_ctg169_3_PKS_AT.2"
                     /NRPS_PKS="type: PKS-like protein"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     hyb_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1093:Beta-ketoacyl synthase (Score: 98.7; E-value:
                     5e-30)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg169_3"
                     /sec_met_domain="PP-binding (E-value: 7.6e-16, bitscore:
                     46.3, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 8.9e-94, bitscore: 301.8,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="hyb_KS (E-value: 6.6e-188, bitscore:
                     612.5, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVKMSFIYSGMGAQWKAMGQQLFRTNELFRRQVEELDPAIQQYTG
                     FSVVEEIVRDKEASRLNAAWIAHPVAFAVEIGITSLLASWGIVPEAVIGHSGGEVVAAY
                     VAGLLSLEDAACLLGAHSRAMRQVEGKGGMLFVGLPFRQVEELIAPFHPDLSIAAINGP
                     RSTVVSGLSGMEGFISLLKEQKVFHRVIPTDVAFHSPQIEPALEEFRHAIDKLSPRPAR
                     MPIYSSFRGQLAAADDFGSSYWVRHIREQVRFAQAIAAMLADGYRLFVEVAPHPLMQTS
                     LMECFAEAGVKAHAMGTLVRDSGSIDDLLRTLIDLEKSGLPVAWDRLSGEERRTVEMLR
                     PHPLSGPSPSKSRLPEPTAILRLISDALAVASSNKLKIEDEHTGFFDLGVDSLTSIRMV
                     RELEAKIGISLPVTTLFDYTSPDALAKHLLTLLAGEGKLEPTSRKDSPLGWKEPIAVVG
                     MGCRFPGGANSPEQFWDLLDQGRTGMREIPVTRWDPGVYYDPDPEKPGTSYTKEAGLLI
                     PDRLDLFDAPFFRIPPREARAIDPQQRILLEVVWETMEQANIPIDGLKGKNVGVYLGIC
                     SDDYKTAHLHSGSMDRIDSYSGSGSMASSAGGRISYVFDFTGPNISVDTACSSSLVALH
                     LACQGLRRDECDVALAAGVNLLVTPHNFVYFSKLGALSPDGRCRSFEAAANGYARGEGC
                     GAVLLKRLSAAQADGDTILAVIRGSAIGQDGASSSFTAPNGLAQQQVIRRALADAGLTP
                     GDVDYIEAHGTGTPLGDPVEVSAYCGVYCDGRSSDRPLLLGSVKANIGHLEGAAGMASL
                     LKVILALRHKRIPPQPAFGAPNPLIPWDKVPLQVIKESTCWETFAAPRRAGVSGFGFSG
                     TNAHMIVEEAPAPPVDASVQELPCHMLVFSARTPEALRDLGERYLDLLRAASASPADIC
                     ATAAFGRPGFPERIAVAGRTAAELAESLKKRLARGLATTTSARDKGVVFLFTGQGSQYP
                     GMGKGLYNAWPAYREVLDHCDRLFSPYLGRSIRELMHGDDEALLASTRHAQPAIFSLQY
                     ALYKLWESWGIRPAAAAGHSIGEFAAACLAGVLSLEDAVYLVARRSALMDSLPGGGLMV
                     SFHATEAEVAPLVAARADKVAIAALNTPRSVVISGESEAVRQIAGQLELTGKRPRYLSV
                     SHPFHSPLMDPLLEPFEQAAAAVRASSARIDLVSGLTGKVATGDDCCSPRYWRRQLREP
                     VRFG"
     CDS_motif       2927..2977
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg169_3_0001"
                     /evalue="3.10E-04"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="ctg169_3"
                     /protein_end="22"
                     /protein_start="5"
                     /score="13.5"
                     /tool="antismash"
                     /translation="FIYSGMGAQWKAMGQQLF"
     aSDomain        2930..3814
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg169_3_PKS_AT.1"
                     /evalue="1.90E-91"
                     /label="ctg169_3_PKS_AT.1"
                     /locus_tag="ctg169_3"
                     /protein_end="301"
                     /protein_start="6"
                     /score="298.3"
                     /specificity="Minowa: mmal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="consensus: pk"
                     /tool="antismash"
                     /translation="IYSGMGAQWKAMGQQLFRTNELFRRQVEELDPAIQQYTGFSVVEE
                     IVRDKEASRLNAAWIAHPVAFAVEIGITSLLASWGIVPEAVIGHSGGEVVAAYVAGLLS
                     LEDAACLLGAHSRAMRQVEGKGGMLFVGLPFRQVEELIAPFHPDLSIAAINGPRSTVVS
                     GLSGMEGFISLLKEQKVFHRVIPTDVAFHSPQIEPALEEFRHAIDKLSPRPARMPIYSS
                     FRGQLAAADDFGSSYWVRHIREQVRFAQAIAAMLADGYRLFVEVAPHPLMQTSLMECFA
                     EAGVKAHAMGTLVRD"
     aSModule        2930..4201
                     /domains="nrpspksdomains_ctg169_3_PKS_AT.1"
                     /domains="nrpspksdomains_ctg169_3_ACP.1"
                     /incomplete
                     /locus_tags="ctg169_3"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       3113..3154
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg169_3_0002"
                     /evalue="2.90E+00"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="ctg169_3"
                     /protein_end="81"
                     /protein_start="67"
                     /score="1.9"
                     /tool="antismash"
                     /translation="HPVAFAVEIGITSLL"
     CDS_motif       3167..3265
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg169_3_0003"
                     /evalue="9.40E-14"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="ctg169_3"
                     /protein_end="118"
                     /protein_start="85"
                     /score="43.5"
                     /tool="antismash"
                     /translation="GIVPEAVIGHSGGEVVAAYVAGLLSLEDAACLLG"
     CDS_motif       3383..3421
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg169_3_0004"
                     /evalue="6.00E-05"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="ctg169_3"
                     /protein_end="170"
                     /protein_start="157"
                     /score="16.1"
                     /tool="antismash"
                     /translation="AAINGPRSTVVSGL"
     CDS_motif       3485..3508
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg169_3_0005"
                     /evalue="2.10E+00"
                     /label="PKSI-AT-M_m6"
                     /locus_tag="ctg169_3"
                     /protein_end="199"
                     /protein_start="191"
                     /score="2.3"
                     /tool="antismash"
                     /translation="PTDVAFHSP"
     CDS_motif       3638..3673
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg169_3_0006"
                     /evalue="1.50E-03"
                     /label="PKSI-AT-M_m8"
                     /locus_tag="ctg169_3"
                     /protein_end="254"
                     /protein_start="242"
                     /score="12.1"
                     /tool="antismash"
                     /translation="YWVRHIREQVRFA"
     CDS_motif       3782..3817
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg169_3_0007"
                     /evalue="4.90E+01"
                     /label="PKSI-KS_m5"
                     /locus_tag="ctg169_3"
                     /protein_end="302"
                     /protein_start="290"
                     /score="-0.9"
                     /tool="antismash"
                     /translation="VKAHAMGTLVRDS"
     aSDomain        4055..4201
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg169_3_ACP.1"
                     /evalue="2.00E-16"
                     /label="ctg169_3_ACP.1"
                     /locus_tag="ctg169_3"
                     /protein_end="430"
                     /protein_start="381"
                     /score="51.9"
                     /tool="antismash"
                     /translation="HTGFFDLGVDSLTSIRMVRELEAKIGISLPVTTLFDYTSPDALAK
                     HLLTL"
     aSDomain        4271..5557
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg169_3_PKS_KS.1"
                     /evalue="5.70E-178"
                     /label="ctg169_3_PKS_KS.1"
                     /locus_tag="ctg169_3"
                     /protein_end="882"
                     /protein_start="453"
                     /score="583.9"
                     /tool="antismash"
                     /translation="IAVVGMGCRFPGGANSPEQFWDLLDQGRTGMREIPVTRWDPGVYY
                     DPDPEKPGTSYTKEAGLLIPDRLDLFDAPFFRIPPREARAIDPQQRILLEVVWETMEQA
                     NIPIDGLKGKNVGVYLGICSDDYKTAHLHSGSMDRIDSYSGSGSMASSAGGRISYVFDF
                     TGPNISVDTACSSSLVALHLACQGLRRDECDVALAAGVNLLVTPHNFVYFSKLGALSPD
                     GRCRSFEAAANGYARGEGCGAVLLKRLSAAQADGDTILAVIRGSAIGQDGASSSFTAPN
                     GLAQQQVIRRALADAGLTPGDVDYIEAHGTGTPLGDPVEVSAYCGVYCDGRSSDRPLLL
                     GSVKANIGHLEGAAGMASLLKVILALRHKRIPPQPAFGAPNPLIPWDKVPLQVIKESTC
                     WETFAAPRRAGVSGFGFSGTNAHMIVEEAPA"
     aSModule        4271..6595
                     /domains="nrpspksdomains_ctg169_3_PKS_KS.1"
                     /domains="nrpspksdomains_ctg169_3_PKS_AT.2"
                     /incomplete
                     /locus_tags="ctg169_3"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       4763..4810
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg169_3_0008"
                     /evalue="1.20E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="ctg169_3"
                     /protein_end="633"
                     /protein_start="617"
                     /score="20.4"
                     /tool="antismash"
                     /translation="GPNISVDTACSSSLVAL"
     CDS_motif       4952..4990
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg169_3_0009"
                     /evalue="2.40E-03"
                     /label="PKSI-KS_m4"
                     /locus_tag="ctg169_3"
                     /protein_end="693"
                     /protein_start="680"
                     /score="11.2"
                     /tool="antismash"
                     /translation="FEAAANGYARGEGC"
     CDS_motif       5183..5230
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg169_3_0010"
                     /evalue="1.50E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="ctg169_3"
                     /protein_end="773"
                     /protein_start="757"
                     /score="13.8"
                     /tool="antismash"
                     /translation="YIEAHGTGTPLGDPVEV"
     CDS_motif       5291..5335
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg169_3_0011"
                     /evalue="5.30E-04"
                     /label="PKSI-KS_m6"
                     /locus_tag="ctg169_3"
                     /protein_end="808"
                     /protein_start="793"
                     /score="12.4"
                     /tool="antismash"
                     /translation="GSVKANIGHLEGAAGM"
     aSDomain        5849..6595
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg169_3_PKS_AT.2"
                     /evalue="1.50E-92"
                     /label="ctg169_3_PKS_AT.2"
                     /locus_tag="ctg169_3"
                     /protein_end="1228"
                     /protein_start="979"
                     /score="301.8"
                     /specificity="Minowa: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="consensus: mal"
                     /tool="antismash"
                     /translation="LFTGQGSQYPGMGKGLYNAWPAYREVLDHCDRLFSPYLGRSIREL
                     MHGDDEALLASTRHAQPAIFSLQYALYKLWESWGIRPAAAAGHSIGEFAAACLAGVLSL
                     EDAVYLVARRSALMDSLPGGGLMVSFHATEAEVAPLVAARADKVAIAALNTPRSVVISG
                     ESEAVRQIAGQLELTGKRPRYLSVSHPFHSPLMDPLLEPFEQAAAAVRASSARIDLVSG
                     LTGKVATGDDCCSPRYWRRQLREPVRFG"
     CDS_motif       5852..5899
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg169_3_0012"
                     /evalue="3.80E-06"
                     /label="PKSI-AT-M_m1"
                     /locus_tag="ctg169_3"
                     /protein_end="996"
                     /protein_start="980"
                     /score="19.3"
                     /tool="antismash"
                     /translation="FTGQGSQYPGMGKGLYN"
     CDS_motif       6029..6061
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg169_3_0013"
                     /evalue="8.70E-03"
                     /label="PKSI-AT-M_m2"
                     /locus_tag="ctg169_3"
                     /protein_end="1050"
                     /protein_start="1039"
                     /score="9.3"
                     /tool="antismash"
                     /translation="QPAIFSLQYALY"
     CDS_motif       6083..6202
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg169_3_0014"
                     /evalue="8.20E-22"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="ctg169_3"
                     /protein_end="1097"
                     /protein_start="1057"
                     /score="69.5"
                     /tool="antismash"
                     /translation="GIRPAAAAGHSIGEFAAACLAGVLSLEDAVYLVARRSALMD"
     CDS_motif       6299..6337
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg169_3_0015"
                     /evalue="1.60E-03"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="ctg169_3"
                     /protein_end="1142"
                     /protein_start="1129"
                     /score="11.8"
                     /tool="antismash"
                     /translation="AALNTPRSVVISGE"
     CDS_motif       6401..6427
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg169_3_0016"
                     /evalue="1.40E-01"
                     /label="PKSI-AT-M_m6"
                     /locus_tag="ctg169_3"
                     /protein_end="1172"
                     /protein_start="1163"
                     /score="5.7"
                     /tool="antismash"
                     /translation="LSVSHPFHSP"
     CDS_motif       6560..6595
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg169_3_0017"
                     /evalue="2.70E-05"
                     /label="PKSI-AT-M_m8"
                     /locus_tag="ctg169_3"
                     /protein_end="1228"
                     /protein_start="1216"
                     /score="17.4"
                     /tool="antismash"
                     /translation="YWRRQLREPVRFG"
ORIGIN
        1 attacaatct caataacctt gactcgatac cccaggttcg tagtttgcca gtggaacttc
       61 ggcaggcgat accggtggtg gggagtgtcc tgccatttag aaccaacagc tatcttgtga
      121 atgaattgat cgactgggac aatgtggaaa cggatccgat ctatcgcctg aatttcccct
      181 gtcgcgaaat gctgcttccc gatcattata agcggataag cgctttgata gagtgtggcg
      241 cctccaggga aaaattgcgt gaggcggtgt ggaaaatccg tcatgagttg aaaccccaat
      301 ccgtgcacgc attggacggg acgttggctt ccctcaatgg acggaaacag cagggcattg
      361 tccatatcta tcctgagacg gtgctatttt tccctgccga aggacagatg tgccatgccc
      421 attgcacctt ctgcttccgt tggctgcaat ttgtggggga ggaagaagaa atattcgcca
      481 gcatggatgt gaatgccttg ataagctatg tagcgcagca tgaagaggtg cgagacattc
      541 tcattaccgg gggcgatccg ctgttcatga gattagacac cctctctaat tatgtagatc
      601 ggattctggc ggcggacatt ccccacctca aaaacatccg tttcggcacc aagacgattt
      661 cctactggcc ttaccgcttt ctcaccgatc ctggtgcaga ggcgctgctg aaactgtttg
      721 agaagatcat taccaaggga aagcatgtgg ccgttatggc acatatcaat cacccccggg
      781 aactggcgac ggaggctgca cagcgggctg tcgcccgcat ccgtgcaacg ggcgccgaaa
      841 taatgtccca gtctcccctg ctgcgccata ttaacgccgc ccctgagatt tggacggaac
      901 tctggcagga acaggtcagg ctcggcatcg tcccctatta ccagtttatt gtccgggata
      961 ccggagcgcg gcattacttt ggcgtgcctc tggtggaggc cctggagata ttccgggcgg
     1021 cctatcgcaa agtaagcgga ctctgccgga cggtccgcgg acctgttatg tcgttgccgc
     1081 aaggcaaagt gcaggtgctt gacgttcatg aatgtgccgg agaaaagggg atcctgctcc
     1141 accatattca agcgcctgat cagaacaggg tgcttaagac cttttttgct gtctatgatg
     1201 aacgggcgca atggtttaca gatctgaaac cgttgcggcc agtggatgca ggttttttcc
     1261 actagattac atttccttaa aggaggctta catatgcaac aaatccgaaa acgaacaaaa
     1321 ctgctggcgt tgtggacagg tcttatactc ttgctgtcga tcagtggatg cgggaacacc
     1381 gattacattt caggtgacgt gggcgcccct ccgccggtca cacagaaaac gcaagctgct
     1441 ctgaaggcag ccgtggacga ttacatgcag tatgtgggga cgccgtccgg cgttcccggc
     1501 acgattgtgg ccgtgaaaat gaacggttat cagccatggt attatgctta cggctcggcc
     1561 gagattgcat tgccgaacaa tcccggttct gcatttacgc aaaaaacagc catggatgcc
     1621 ggcatgccct tccgcatcgc cagcattacc aagatgttca tcgcccaagc agtgattcag
     1681 ttggctcagg aagggaagat cgatcttgat cagacggtgg aaaattatct gccgggggcc
     1741 ttaacgggga aaaacctggc caacaaagac aaaattacca tcaatatgct tctcaatcat
     1801 acaagcggtc tttacagtta tgttacctcg gacgccggtc tcttgcatgg taacctccct
     1861 acggctgccg gcacgacggg acttcggctc ctccccatgg atacttttgt cgagggcctg
     1921 gggctgaccg cctggtccca ctcctattct cctcaggaca ctattctgca gtttgccaat
     1981 accttcagcc cccctctatc ccttgtggat acgatcacgg gcgcaatcgg caacccttac
     2041 ggctccaacc cctactttgc tccagggacg gatttacact attccaacac caattattat
     2101 ctgctgggac ttctgatcca gaagatagcc acgcagtatg aaacagatcc tgccaagcaa
     2161 acggttgaat accagataaa gcggttgatc accgatccgc tcaaactttc ggatacctac
     2221 ctgcctacaa ccaagacctt taacaatcct gttcacgtgc atggttatgc ggattatttt
     2281 aacagtgaag cttacagaac agccatgagt gacaacctgc tcaagttcag tgcatgccaa
     2341 aacaactctg cctggtgcac cggagatggc atcctggaag acttcaccga aatcgatccc
     2401 tcttttgcct ggactaccgg gggcatgatt tccagcgcca aagatttgct gacttttgcg
     2461 cagtttgtca cgcaaacacg cgtgcagacc ggacaggaag cggggaaatg gatcaatggt
     2521 tcgccgctgg acaattccac gactttccag tacggacgag gtatagcgcg catcaataac
     2581 gtcatgtttg gtcatggcgg acagtttgca ggatacaacg tggctgtcta ttggtacgcc
     2641 cctctcgata tttatttcat ggtcatgaca aataagtatt cctacacgga aaatgatccc
     2701 aatgatctcg gggggtcaat tgtagcgggg gccgattcca tgtatgcgct gtcggtaaaa
     2761 cagacgactg ctgctccggt tgatcacaat cgctccatta tcaacagcct gatcactgct
     2821 ctggagcagg atccaaacgt ggcaaaaaaa ggagctaccc ctgttcggct ttccagttat
     2881 ttcctcgaga tgtgaaggca agagacaatc catggtcaaa atgtccttta tatattcagg
     2941 aatgggcgct caatggaagg ccatgggaca gcagcttttc aggaccaatg agctcttccg
     3001 ccggcaggtg gaagagctcg accctgccat tcaacaatac acaggttttt cagttgtaga
     3061 agaaattgta cgcgataaag aagcatcccg tcttaacgcc gcctggatag cccatccggt
     3121 tgcctttgcc gtcgagatag gcattacctc cctgttggct tcgtggggga tcgttccgga
     3181 agctgtaatc ggtcatagcg gcggtgaagt agtcgcggct tatgttgccg ggttgctttc
     3241 tctggaggat gcagcctgcc ttttgggcgc ccatagtcga gccatgcgcc aggtagaggg
     3301 aaaggggggg atgctttttg taggcctccc gttccggcaa gtggaagaat tgattgcccc
     3361 tttccatccc gatctctcca ttgcggccat caatggtcct cgttccaccg tagtttcagg
     3421 tcttagcggc atggagggat tcatctcact attgaaagaa cagaaggtat ttcaccgcgt
     3481 catcccaacg gatgtcgctt tccacagccc tcaaatagag cctgctcttg aggaatttcg
     3541 gcatgccata gacaaacttt ccccccgtcc ggcaagaatg ccgatctatt cttcctttag
     3601 gggtcagtta gccgcagccg atgatttcgg ctcctcgtac tgggtccgcc atatcaggga
     3661 acaggtgagg tttgcccagg ccattgccgc catgctcgcc gatggatatc gcctttttgt
     3721 ggaggtcgcg ccccatccac ttatgcagac ctcgctgatg gaatgctttg ccgaggcagg
     3781 agtcaaggcg catgccatgg ggaccctggt gcgggattcc ggcagtattg atgacctgct
     3841 gcgtaccctg attgaccttg aaaagagtgg cttgcccgtg gcctgggacc gattgagcgg
     3901 agaggagcga cgtactgtcg agatgctgcg gccccatcct ttgtcaggcc catccccttc
     3961 aaagtcacgg cttccggagc ctaccgctat cttgcgtctg atcagcgacg cactcgctgt
     4021 ggcgagttcc aataaattga agattgaaga cgaacatacc ggtttttttg atctgggtgt
     4081 cgactccctg acgagcattc ggatggtaag ggagttggaa gcaaagatcg gtatctctct
     4141 gccggtgacc accctcttcg attatacctc tcccgacgcc cttgccaagc atctgctcac
     4201 gcttcttgcc ggcgagggca aactggaacc tacgtcaagg aaagacagcc ctcttggctg
     4261 gaaagaacct atcgccgtcg tgggaatggg ctgccgtttc cccgggggag caaattcgcc
     4321 agagcagttt tgggacttgc tagaccaggg aagaacgggc atgcgagaga tcccggtcac
     4381 ccgctgggac ccgggcgtgt attatgatcc agatccggaa aaacccggca cgagctatac
     4441 caaggaggcg ggccttctca tccctgaccg gcttgacctc tttgacgccc ccttctttcg
     4501 tatccctccc cgtgaagctc gggcgattga tccccagcag cgcatcctgc ttgaggtagt
     4561 ctgggagacc atggagcagg ccaatattcc gatcgatggg ttgaagggaa agaacgtcgg
     4621 cgtctattta ggcatctgca gcgatgacta caagaccgcc catctccatt ccggcagtat
     4681 ggaccgtatc gactcctatt ccgggtccgg ttccatggcc agttcggccg gcggaagaat
     4741 atcctatgtc tttgatttta caggacctaa tatctcggtg gatacggcct gttcctcctc
     4801 tttggtggcg ctccatctgg cctgccaggg cctgcggcgc gacgagtgcg atgttgccct
     4861 ggccgccggg gttaacctgc ttgtgacgcc gcacaatttt gtctattttt ccaaactggg
     4921 ggcgctctct cctgacgggc gttgccggtc ttttgaggcg gcggccaatg gttacgcccg
     4981 gggcgaaggg tgtggggcag tcctgctcaa acgtctctca gccgcccaag cggacggcga
     5041 taccatcctg gctgtgatca gaggcagcgc cattggtcag gacggggcca gttccagctt
     5101 taccgcaccg aatggtctcg cgcaacagca ggtcatccgc agggctttgg ccgatgccgg
     5161 actcacgccc ggggatgtcg attatataga ggcccacggg accggtaccc ccttgggcga
     5221 tcctgtggag gtgtccgctt actgcggagt ttactgcgat ggccgctctt ccgacaggcc
     5281 cttgctgctt ggttcggtga aggccaatat cggccacctg gaaggtgcgg cagggatggc
     5341 gagccttctc aaagtgattc tggccctgcg ccataaaagg attcctcctc agcccgcatt
     5401 cggcgcgcca aatcccctca tcccctggga taaggtgccg ctccaggtga tcaaggaatc
     5461 cacgtgctgg gagacctttg cggcaccgcg gagggcaggg gtgagcggtt ttggtttcag
     5521 cggcaccaac gcccatatga ttgtcgagga ggcgccagct ccgccggttg atgcctcagt
     5581 acaggaactt ccgtgccaca tgcttgtctt ttctgcccgc acacccgagg ccctgcggga
     5641 ccttggcgag cgctatctcg acctgcttcg ggctgccagc gcttcgcccg ccgacatttg
     5701 tgctactgcg gcctttggcc gccccggctt tcccgaacga attgcggttg ccggacgcac
     5761 ggctgctgaa ctggccgaaa gcctgaaaaa acgcctggcc agaggattgg cgacaacgac
     5821 gtccgcccga gacaaagggg tcgtatttct ctttaccggc cagggatccc agtacccagg
     5881 tatgggaaaa ggtctgtaca acgcctggcc ggcctatcga gaggtcctcg accactgtga
     5941 tcggcttttt tccccctatt tggggcgatc gatccgggag ctgatgcatg gcgatgatga
     6001 agcactgctg gctagtaccc gccacgccca acccgccatc ttctctctcc agtacgcctt
     6061 gtacaaacta tgggagtcct gggggatccg gccggccgct gccgccggac acagtatcgg
     6121 cgagtttgcc gctgcctgtc tggccggcgt gctctccctg gaagatgccg tatatctggt
     6181 tgcccgtcgc tccgccttga tggattccct cccgggtggc ggcttgatgg tttctttcca
     6241 tgctaccgaa gcggaggttg cgccgctggt ggccgctcgg gccgacaagg tggccatcgc
     6301 cgctctcaat accccccgga gtgtagtgat ctcaggcgag agtgaggcgg tgaggcagat
     6361 cgccggccag ctggaactga cggggaagcg gccaaggtat ctctcggtat ctcacccctt
     6421 ccactctccg ctgatggatc cgcttctcga accgtttgaa caggcggccg ctgccgtccg
     6481 cgcctcttca gcccgcatcg acttggtgtc cggactgacg ggaaaggttg ccacaggcga
     6541 cgattgctgc tcgcctcggt actggcggcg tcagttgcga gagccggtcc gttttggcg
//
