LOCUS       c00004_3300013..       14023 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300013137.a:Ga0172375_10008274.
ACCESSION   c00004_3300013..
VERSION     c00004_3300013..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-24 15:51:26
            Original ID  :: 3300013137.a:Ga0172375_10008274
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14023
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14023
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2:11207]"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3..11207
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
     cand_cluster    1..14023
                     /SMILES="C=CC(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="single"
                     /product="T1PKS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..14023
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T1PKS"
                     /region_number="1"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /tool="antismash"
     CDS             complement(3..4550)
                     /NRPS_PKS="Domain: PKS_KS(Hybrid-KS) (33-461). E-value:
                     3.7e-187. Score: 614.1. Matches aSDomain:
                     nrpspksdomains_ctg4_1_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (564-857). E-value: 3.6e-107.
                     Score: 349.9. Matches aSDomain:
                     nrpspksdomains_ctg4_1_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_DH (928-1117). E-value: 4.3e-25.
                     Score: 80.7. Matches aSDomain:
                     nrpspksdomains_ctg4_1_PKS_DH.1"
                     /NRPS_PKS="type: PKS-like protein"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     hyb_KS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1093:Beta-ketoacyl synthase (Score: 129.6; E-value:
                     2.1e-39)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_1"
                     /sec_met_domain="PKS_AT (E-value: 2.8e-108, bitscore:
                     349.9, seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="hyb_KS (E-value: 7e-200, bitscore: 652.3,
                     seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDVTTYQDALKKASSTIKQLITENERLKRRESIAIIGLGCRLPG
                     GANSPEEYWRLLAEGRDAISPIPAKRWSAGHYFSHDQDSPGRMYVREGGFLDFYPYDFD
                     APFFGISPKEAKSLDPQQRLLLETAWEALEDAGINPASLQGSRTGVFIGISSNDYDSAH
                     LRSGDPSLIDPYSLTGFTFSTAAGRISYFLGLEGPNFPVDTACSSSLVALHLACRSLRN
                     RECQMALVGGVNLMLTPEPLIAFCKLRALSPDGRCKTFDADANGYGRGAGCGMIVLKRM
                     DAAEKDGDRILAVIRGSALNSDGRSNGLTAPNGMAQRRVIRAALEDAALMPGDIDYLEA
                     HGTGTSLGDPIEIEAIAAVLGQGRDPDHPLLVGSVKTNIGHLEAAAGIAGVIKLVLALN
                     HEKIPSHLHFNTPNPHVAWDRLPLSIVSGGASWSRSSRPRRAGISCFGFSGTNAHAILE
                     EAPLNAFPPADGRTSHLLAISAAGEVALRSLAGRYATYLQGPALPPLAAICHTAASGRN
                     TFSHGLAVVGNTSTELAERLSAFVEQGTTKGIYLRSSQSREKPSPVFLFTGQGSQYPGM
                     GRELYATSPVYREALDRCDSLFAPLIGLSIRDLMHGDSEEQLACTIYAQPAIFSLEYSL
                     ACLWSSWGVRPSAVVGHSIGEFVAACLAGVLALEDAVTLVAHRGRLMNALPAGGVMAAV
                     RCSEAAILPALAPHAGRVSLAVVNSPGSVVISGDRVGVAGVLETLQQQGFSSQYLNVSH
                     AFHSPLMDPVLEEFEGIAASLTFHEPTLTVISNVTGKPAVGDDLRTASYWRRHLRGSVR
                     FSESVEFLNKQGHDLFLEVGATATLSSFVRQIAGADCRLVASLKRRVPPWSTLMAALGD
                     LFAAGVAIDWQGFDAPYRAGRVSLPTYPFQRERYIMDPVHEPGGRGTAKGISLMGEEHP
                     LLGRRMDAPSVEKRFVGALGTTDDPWLAGHVIHGAVIVPAAAYLEMALASAVPQFLPAA
                     PLLLEKARFAMPLLLTEERKSLQTIYRPDTGAVEVFSLASQGQWQLHASLTVRPLSGQK
                     VSYPPLQGSLAPQFPAAGGEKEEGMSSVARQALAGKEKSNDEGGIAVDGDRYYSDLLEK
                     GYCYTGVFRSIRRLRFCGAHISGDVEIPQEAAAGFVMHPALLDGCLTLTGASFLYGPEP
                     LPDAVAFVPAEIDSLLFSGAQASCLQVRCVQQERSQASARFDLIATDRDGAPVLQITGL
                     TLRRIRKEQMLSRSTTVLSDLMYQVLWRECAPAAPASSLSGRWVALTDPSPCAAALSEV
                     LKGCGVSLTEVVKAGSEGGKEGRIAVDPFSPEDMESLALDLRNSPEPVAGLVSFWGEDL
                     TGNLNLVKGLLAAKISVPLFLVTAGVHNPSGMDRENRPEGAPLWGFGATVAAEHPELSC
                     RLLDLSPWPGKDEGAQFVNELAVRDGEDRVALRGRRRFVPRLCRAESQELSKGMILPKK
                     DGFYIDVDQRGSLEGLCVRTRGRVAPEPGEVEVQVRAVGLNFRDVLNVLGQYPGD"
     CDS_motif       complement(18..53)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_1_0013"
                     /evalue="7.80E-04"
                     /label="PKSI-ER_m1"
                     /locus_tag="ctg4_1"
                     /protein_end="1511"
                     /protein_start="1499"
                     /score="12.4"
                     /tool="antismash"
                     /translation="GLNFRDVLNVLGQ"
     aSDomain        complement(1200..1766)
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg4_1_PKS_DH.1"
                     /evalue="4.30E-25"
                     /label="ctg4_1_PKS_DH.1"
                     /locus_tag="ctg4_1"
                     /protein_end="1117"
                     /protein_start="928"
                     /score="80.7"
                     /tool="antismash"
                     /translation="HPLLGRRMDAPSVEKRFVGALGTTDDPWLAGHVIHGAVIVPAAAY
                     LEMALASAVPQFLPAAPLLLEKARFAMPLLLTEERKSLQTIYRPDTGAVEVFSLASQGQ
                     WQLHASLTVRPLSGQKVSYPPLQGSLAPQFPAAGGEKEEGMSSVARQALAGKEKSNDEG
                     GIAVDGDRYYSDLLEKGYCYTGVFRSI"
     aSModule        1200..4451
                     /domains="nrpspksdomains_ctg4_1_PKS_KS.1"
                     /domains="nrpspksdomains_ctg4_1_PKS_AT.1"
                     /domains="nrpspksdomains_ctg4_1_PKS_DH.1"
                     /incomplete
                     /locus_tags="ctg4_1"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       complement(1614..1685)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_1_0012"
                     /evalue="8.90E-12"
                     /label="PKSI-DH_m2"
                     /locus_tag="ctg4_1"
                     /protein_end="979"
                     /protein_start="955"
                     /score="37.4"
                     /tool="antismash"
                     /translation="WLAGHVIHGAVIVPAAAYLEMALAS"
     aSDomain        complement(1980..2858)
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg4_1_PKS_AT.1"
                     /evalue="3.60E-107"
                     /label="ctg4_1_PKS_AT.1"
                     /locus_tag="ctg4_1"
                     /protein_end="857"
                     /protein_start="564"
                     /score="349.9"
                     /specificity="Minowa: mal"
                     /specificity="consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /tool="antismash"
                     /translation="LFTGQGSQYPGMGRELYATSPVYREALDRCDSLFAPLIGLSIRDL
                     MHGDSEEQLACTIYAQPAIFSLEYSLACLWSSWGVRPSAVVGHSIGEFVAACLAGVLAL
                     EDAVTLVAHRGRLMNALPAGGVMAAVRCSEAAILPALAPHAGRVSLAVVNSPGSVVISG
                     DRVGVAGVLETLQQQGFSSQYLNVSHAFHSPLMDPVLEEFEGIAASLTFHEPTLTVISN
                     VTGKPAVGDDLRTASYWRRHLRGSVRFSESVEFLNKQGHDLFLEVGATATLSSFVRQIA
                     GADCRLVASLKRR"
     CDS_motif       complement(2112..2147)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_1_0011"
                     /evalue="6.80E-04"
                     /label="PKSI-AT-M_m8"
                     /locus_tag="ctg4_1"
                     /protein_end="813"
                     /protein_start="801"
                     /score="13.1"
                     /tool="antismash"
                     /translation="YWRRHLRGSVRFS"
     CDS_motif       complement(2280..2306)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_1_0010"
                     /evalue="9.00E-03"
                     /label="PKSI-AT-M_m6"
                     /locus_tag="ctg4_1"
                     /protein_end="757"
                     /protein_start="748"
                     /score="9.2"
                     /tool="antismash"
                     /translation="LNVSHAFHSP"
     CDS_motif       complement(2367..2408)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_1_0009"
                     /evalue="8.70E-03"
                     /label="PKSI-AT-mM_m5"
                     /locus_tag="ctg4_1"
                     /protein_end="728"
                     /protein_start="714"
                     /score="8.7"
                     /tool="antismash"
                     /translation="AVVNSPGSVVISGDR"
     CDS_motif       complement(2502..2624)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_1_0008"
                     /evalue="2.80E-24"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="ctg4_1"
                     /protein_end="683"
                     /protein_start="642"
                     /score="77.5"
                     /tool="antismash"
                     /translation="GVRPSAVVGHSIGEFVAACLAGVLALEDAVTLVAHRGRLMNA"
     CDS_motif       complement(2643..2678)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_1_0007"
                     /evalue="6.10E-03"
                     /label="PKSI-AT-M_m2"
                     /locus_tag="ctg4_1"
                     /protein_end="636"
                     /protein_start="624"
                     /score="9.7"
                     /tool="antismash"
                     /translation="QPAIFSLEYSLAC"
     CDS_motif       complement(2718..2744)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_1_0006"
                     /evalue="4.50E+01"
                     /label="PKSI-ER_m1"
                     /locus_tag="ctg4_1"
                     /protein_end="611"
                     /protein_start="602"
                     /score="-1.7"
                     /tool="antismash"
                     /translation="GLSIRDLMHG"
     CDS_motif       complement(2808..2855)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_1_0005"
                     /evalue="2.90E-07"
                     /label="PKSI-AT-M_m1"
                     /locus_tag="ctg4_1"
                     /protein_end="581"
                     /protein_start="565"
                     /score="22.6"
                     /tool="antismash"
                     /translation="FTGQGSQYPGMGRELYA"
     aSDomain        complement(3168..4451)
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg4_1_PKS_KS.1"
                     /evalue="3.70E-187"
                     /label="ctg4_1_PKS_KS.1"
                     /locus_tag="ctg4_1"
                     /protein_end="461"
                     /protein_start="33"
                     /score="614.1"
                     /tool="antismash"
                     /translation="IAIIGLGCRLPGGANSPEEYWRLLAEGRDAISPIPAKRWSAGHYF
                     SHDQDSPGRMYVREGGFLDFYPYDFDAPFFGISPKEAKSLDPQQRLLLETAWEALEDAG
                     INPASLQGSRTGVFIGISSNDYDSAHLRSGDPSLIDPYSLTGFTFSTAAGRISYFLGLE
                     GPNFPVDTACSSSLVALHLACRSLRNRECQMALVGGVNLMLTPEPLIAFCKLRALSPDG
                     RCKTFDADANGYGRGAGCGMIVLKRMDAAEKDGDRILAVIRGSALNSDGRSNGLTAPNG
                     MAQRRVIRAALEDAALMPGDIDYLEAHGTGTSLGDPIEIEAIAAVLGQGRDPDHPLLVG
                     SVKTNIGHLEAAAGIAGVIKLVLALNHEKIPSHLHFNTPNPHVAWDRLPLSIVSGGASW
                     SRSSRPRRAGISCFGFSGTNAHAILEEAPL"
     CDS_motif       complement(3390..3434)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_1_0004"
                     /evalue="2.50E-04"
                     /label="PKSI-KS_m6"
                     /locus_tag="ctg4_1"
                     /protein_end="387"
                     /protein_start="372"
                     /score="13.3"
                     /tool="antismash"
                     /translation="GSVKTNIGHLEAAAGI"
     CDS_motif       complement(3495..3542)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_1_0003"
                     /evalue="2.40E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="ctg4_1"
                     /protein_end="352"
                     /protein_start="336"
                     /score="13.2"
                     /tool="antismash"
                     /translation="YLEAHGTGTSLGDPIEI"
     CDS_motif       complement(3735..3773)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_1_0002"
                     /evalue="4.20E-03"
                     /label="PKSI-KS_m4"
                     /locus_tag="ctg4_1"
                     /protein_end="272"
                     /protein_start="259"
                     /score="10.5"
                     /tool="antismash"
                     /translation="FDADANGYGRGAGC"
     CDS_motif       complement(3915..3962)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_1_0001"
                     /evalue="4.70E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="ctg4_1"
                     /protein_end="212"
                     /protein_start="196"
                     /score="18.6"
                     /tool="antismash"
                     /translation="GPNFPVDTACSSSLVAL"
     CDS             complement(4554..11207)
                     /NRPS_PKS="Domain: PKS_AT (6-301). E-value: 4.1e-91. Score:
                     297.2. Matches aSDomain: nrpspksdomains_ctg4_2_PKS_AT.1"
                     /NRPS_PKS="Domain: ACP (381-430). E-value: 3.9e-16. Score:
                     50.9. Matches aSDomain: nrpspksdomains_ctg4_2_ACP.1"
                     /NRPS_PKS="Domain: PKS_KS(Hybrid-KS) (453-882). E-value:
                     1.6e-177. Score: 582.3. Matches aSDomain:
                     nrpspksdomains_ctg4_2_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (979-1273). E-value: 5.6e-103.
                     Score: 336.1. Matches aSDomain:
                     nrpspksdomains_ctg4_2_PKS_AT.2"
                     /NRPS_PKS="Domain: PKS_DH (1336-1503). E-value: 2.5e-28.
                     Score: 91.2. Matches aSDomain:
                     nrpspksdomains_ctg4_2_PKS_DH.1"
                     /NRPS_PKS="Domain: PKS_KR (1835-2011). E-value: 3.1e-55.
                     Score: 178.7. Matches aSDomain:
                     nrpspksdomains_ctg4_2_PKS_KR.1"
                     /NRPS_PKS="Domain: ACP (2114-2182). E-value: 4.1e-15.
                     Score: 47.6. Matches aSDomain: nrpspksdomains_ctg4_2_ACP.2"
                     /NRPS_PKS="type: PKS-like protein"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     hyb_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1093:Beta-ketoacyl synthase (Score: 97.3; E-value:
                     1.3e-29)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_2"
                     /sec_met_domain="PP-binding (E-value: 2e-15, bitscore:
                     45.3, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 4.4e-104, bitscore:
                     336.1, seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="hyb_KS (E-value: 2.6e-187, bitscore:
                     610.9, seeds: 33, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 1.3e-54, bitscore:
                     173.0, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVKMSFIYSGMGAQWKAMGQQLFRTNELFRRQVEELDPAIQQYTG
                     FSVVEEIVRDKEASRLNAPWIAHPVAFAVEIGITSLLASWGIVPEAVIGHSGGEVVAAY
                     VAGLLSLEDAACLLGAHSRAMRQVEGKGGMLFVGLPFRQVEELIAPFHPDLSIAAINGP
                     RSTVVSGLSGMEGFISLLKEQKVFHRVIPTDVAFHSPQIEPALEEFRHAIDKLSPRPAR
                     MPIYSSFRGQLAAADDFGSSYWVRHIREQVRFAQAIAAMLADGYRLFVEVAPHPLMQTS
                     LMECFAEAGVKAHAMGTLVRDSGSIDDLLRTLIDLEKSGLPVAWDRLSGEERRTVEMLR
                     PHPLSGPSPSKSRLPEPTAILRLISDALAVASSNKLKIEDEHTGFFDLGVDSLTSIRMV
                     RELEAKIGISLPVTTLFDYTSPDALAKHLLTLLAGEGKLEPTSRKDSPLGWKEPIAVVG
                     MGCRFPGGANSPEQFWDLLDQGRTGMREIPVTRWDPGVYYDPDPEKPGTSYTKEAGLLI
                     PDRLDLFDAPFFRIPPREARAIDPQQRILLEVVWETMEQANIPIDGLKGKNVGVYLGIC
                     SDDYKTAHLHSGSMDRIDSYSGSGSMASSAGGRISYVFDFTGPNISVDTACSSSLVALH
                     LACQGLRRDECDVALAAGVNLLVTPHNFVYFSKLGALSPDGRCRSFEAAANGYARGEGC
                     GAVLLKRLSAAQADGDTILAVIRGSAIGQDGASSSFTAPNGLAQQQVIRRALADAGLTP
                     GDVDYIEAHGTGTPLGDPVEVSAYCGVYCDGRSSDRPLLLGSVKANIGHLEGAAGMASL
                     LKVILALRHKRIPPQPAFGAPNPLIPWDKVPLQVIKESTCWETFAAPRRAGVSGFGFSG
                     TNAHMIVEEAPAPPVDASVQELPCHMLVFSARTPEALRDLGERYLDLLRAASASPADIC
                     ATAAFGRPGFPERIAVAGRTAAELAESLKKRLARGLATTTSARDKGVVFLFTGQGSQYP
                     GMGKGLYNAWPAYREVLDHCDRLFSPYLGRSIRELMHGDDEALLASTRHAQPAIFSLQY
                     ALYKLWESWGIRPAAAAGHSIGEFAAACLAGVLSLEDAVYLVARRSALMDSLPGGGLMV
                     SFHATEAEVAPLVAARADKVAIAALNTPRSVVISGESEAVRQIAGQLELTGKRPRYLSV
                     SHPFHSPLMDPLLEPFEQAAAAVRASSARIDLVSGLTGKVATGDDCCSPRYWRRQLREP
                     VRFGAALETLLQEGYAAFVEIGAAPILSAFGKTISADPGHAWLPSLRPGHDDLRQIAGS
                     LCMLAERGVASARTYYSGCERRTVQLPAYPFQRASYWTEPLLSATAAAPSGSHPLLGER
                     IDSPALGEGVIYSTLFTPATPRFLAEHVIFDRVLSPAAAHLCMLAAAMRGVSDDPSLPV
                     MLRDVHFVRPLLVGQEGRNVQVLVSAPSAGVRSLRIVSRYRDERAPHWQEHCLGSAFSG
                     VTIPEAEPFALIRKRCTRQLDPAEFYAAFLAAGYKVGPSYQRIKEILAGDGESLCRLEG
                     VAHPADPDPGLMDAILHSMGATSQEFRQAIEGGERIYIPVGAQEVVFVAPLGAEIWCHS
                     RALTTADAIESQVRVYSAEGALLMAVSGFSLRRTDRKTMYATERTEGLLYHLNWKALPE
                     SSQEVAQGRYLVIGEDAVAGSISTAISSLGHSSTSLSPKAALSETQTWGKNGEALTILL
                     AASLAEPESGMMGLPEQLAGLSSLIAGLAERFHHTAGAKLWLVTQRAAAASGPPPNPLQ
                     AACQGLGRAAALEYPEIWGGIIDLDDTAFSFPALSKLISFLADPGSEREIALRGGNLYC
                     PRMEHLSVPGESGPLFCNDASYLITGGAGALGLALAESLVTAGVKHLCLSGRHVPAGEA
                     AERIAALASAGAAVTFMKADVSSGPEVERLLAVMQTTMPRLAGVFHLAGVLDDAPLASL
                     DAERLRRSLGAKAAGAWHLHRLCAGLKLDHFVLFSSAAGVLGNRGQGAYCAANAFLDGL
                     SGWRRSQGQPALSIAWGPLSGGGMAESSDTVKRLVERQGFNYILAETVLPIVEQACRAP
                     YPCIAAVRCDWDRYQEFYRLSPGGLLSGLTSRQHSPLEVEDRSPILRELQEADPAARRA
                     LLTRHLQQRAGEVIGLPVNRLDIGAPLVELGLDSLMMVDLRNVLVKDLGANLTVATLFN
                     FPSLDSLAGHLLADQLALSPSVAAPDIRTPELADTARDLLAELKELIG"
     aSDomain        complement(4662..4865)
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg4_2_ACP.2"
                     /evalue="4.10E-15"
                     /label="ctg4_2_ACP.2"
                     /locus_tag="ctg4_2"
                     /protein_end="2182"
                     /protein_start="2114"
                     /score="47.6"
                     /tool="antismash"
                     /translation="HLQQRAGEVIGLPVNRLDIGAPLVELGLDSLMMVDLRNVLVKDLG
                     ANLTVATLFNFPSLDSLAGHLLAD"
     aSModule        4662..9848
                     /complete
                     /domains="nrpspksdomains_ctg4_2_PKS_KS.1"
                     /domains="nrpspksdomains_ctg4_2_PKS_AT.2"
                     /domains="nrpspksdomains_ctg4_2_PKS_DH.1"
                     /domains="nrpspksdomains_ctg4_2_PKS_KR.1"
                     /domains="nrpspksdomains_ctg4_2_ACP.2"
                     /locus_tags="ctg4_2"
                     /monomer_pairings="mal -> ccmal"
                     /tool="antismash"
                     /type="pks"
     aSDomain        complement(5175..5702)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg4_2_PKS_KR.1"
                     /evalue="3.10E-55"
                     /label="ctg4_2_PKS_KR.1"
                     /locus_tag="ctg4_2"
                     /protein_end="2011"
                     /protein_start="1835"
                     /score="178.7"
                     /specificity="KR stereochemistry: B1"
                     /specificity="KR activity: active"
                     /tool="antismash"
                     /translation="SYLITGGAGALGLALAESLVTAGVKHLCLSGRHVPAGEAAERIAA
                     LASAGAAVTFMKADVSSGPEVERLLAVMQTTMPRLAGVFHLAGVLDDAPLASLDAERLR
                     RSLGAKAAGAWHLHRLCAGLKLDHFVLFSSAAGVLGNRGQGAYCAANAFLDGLSGWRRS
                     QGQPALSIAWGPLS"
     CDS_motif       complement(5217..5327)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_2_0018"
                     /evalue="8.20E-21"
                     /label="PKSI-KR_m4"
                     /locus_tag="ctg4_2"
                     /protein_end="1997"
                     /protein_start="1960"
                     /score="66.6"
                     /tool="antismash"
                     /translation="LDHFVLFSSAAGVLGNRGQGAYCAANAFLDGLSGWRRS"
     CDS_motif       complement(5607..5702)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_2_0017"
                     /evalue="1.10E-10"
                     /label="PKSI-KR_m1"
                     /locus_tag="ctg4_2"
                     /protein_end="1867"
                     /protein_start="1835"
                     /score="34.1"
                     /tool="antismash"
                     /translation="SYLITGGAGALGLALAESLVTAGVKHLCLSGRH"
     aSDomain        complement(6699..7199)
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg4_2_PKS_DH.1"
                     /evalue="2.50E-28"
                     /label="ctg4_2_PKS_DH.1"
                     /locus_tag="ctg4_2"
                     /protein_end="1503"
                     /protein_start="1336"
                     /score="91.2"
                     /tool="antismash"
                     /translation="HPLLGERIDSPALGEGVIYSTLFTPATPRFLAEHVIFDRVLSPAA
                     AHLCMLAAAMRGVSDDPSLPVMLRDVHFVRPLLVGQEGRNVQVLVSAPSAGVRSLRIVS
                     RYRDERAPHWQEHCLGSAFSGVTIPEAEPFALIRKRCTRQLDPAEFYAAFLAAGYKVGP
                     SYQRI"
     CDS_motif       complement(7035..7112)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_2_0016"
                     /evalue="6.20E-07"
                     /label="PKSI-DH_m2"
                     /locus_tag="ctg4_2"
                     /protein_end="1391"
                     /protein_start="1365"
                     /score="22.0"
                     /tool="antismash"
                     /translation="FLAEHVIFDRVLSPAAAHLCMLAAAMR"
     CDS_motif       complement(7230..7256)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_2_0015"
                     /evalue="4.00E+01"
                     /label="PKSI-AT-mM_m8"
                     /locus_tag="ctg4_2"
                     /protein_end="1326"
                     /protein_start="1317"
                     /score="-1.6"
                     /tool="antismash"
                     /translation="ASYWTEPLLS"
     aSDomain        complement(7389..8270)
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg4_2_PKS_AT.2"
                     /evalue="5.60E-103"
                     /label="ctg4_2_PKS_AT.2"
                     /locus_tag="ctg4_2"
                     /protein_end="1273"
                     /protein_start="979"
                     /score="336.1"
                     /specificity="Minowa: mal"
                     /specificity="consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /tool="antismash"
                     /translation="LFTGQGSQYPGMGKGLYNAWPAYREVLDHCDRLFSPYLGRSIREL
                     MHGDDEALLASTRHAQPAIFSLQYALYKLWESWGIRPAAAAGHSIGEFAAACLAGVLSL
                     EDAVYLVARRSALMDSLPGGGLMVSFHATEAEVAPLVAARADKVAIAALNTPRSVVISG
                     ESEAVRQIAGQLELTGKRPRYLSVSHPFHSPLMDPLLEPFEQAAAAVRASSARIDLVSG
                     LTGKVATGDDCCSPRYWRRQLREPVRFGAALETLLQEGYAAFVEIGAAPILSAFGKTIS
                     ADPGHAWLPSLRPG"
     CDS_motif       complement(7524..7559)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_2_0014"
                     /evalue="5.20E-05"
                     /label="PKSI-AT-M_m8"
                     /locus_tag="ctg4_2"
                     /protein_end="1228"
                     /protein_start="1216"
                     /score="16.5"
                     /tool="antismash"
                     /translation="YWRRQLREPVRFG"
     CDS_motif       complement(7782..7820)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_2_0013"
                     /evalue="3.10E-03"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="ctg4_2"
                     /protein_end="1142"
                     /protein_start="1129"
                     /score="10.9"
                     /tool="antismash"
                     /translation="AALNTPRSVVISGE"
     CDS_motif       complement(7917..8036)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_2_0012"
                     /evalue="1.60E-21"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="ctg4_2"
                     /protein_end="1097"
                     /protein_start="1057"
                     /score="68.6"
                     /tool="antismash"
                     /translation="GIRPAAAAGHSIGEFAAACLAGVLSLEDAVYLVARRSALMD"
     CDS_motif       complement(8040..8096)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_2_0011"
                     /evalue="3.50E-02"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="ctg4_2"
                     /protein_end="1056"
                     /protein_start="1037"
                     /score="7.7"
                     /tool="antismash"
                     /translation="HAQPAIFSLQYALYKLWESW"
     CDS_motif       complement(8220..8267)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_2_0010"
                     /evalue="7.50E-06"
                     /label="PKSI-AT-M_m1"
                     /locus_tag="ctg4_2"
                     /protein_end="996"
                     /protein_start="980"
                     /score="18.4"
                     /tool="antismash"
                     /translation="FTGQGSQYPGMGKGLYN"
     aSDomain        complement(8562..9848)
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg4_2_PKS_KS.1"
                     /evalue="1.60E-177"
                     /label="ctg4_2_PKS_KS.1"
                     /locus_tag="ctg4_2"
                     /protein_end="882"
                     /protein_start="453"
                     /score="582.3"
                     /tool="antismash"
                     /translation="IAVVGMGCRFPGGANSPEQFWDLLDQGRTGMREIPVTRWDPGVYY
                     DPDPEKPGTSYTKEAGLLIPDRLDLFDAPFFRIPPREARAIDPQQRILLEVVWETMEQA
                     NIPIDGLKGKNVGVYLGICSDDYKTAHLHSGSMDRIDSYSGSGSMASSAGGRISYVFDF
                     TGPNISVDTACSSSLVALHLACQGLRRDECDVALAAGVNLLVTPHNFVYFSKLGALSPD
                     GRCRSFEAAANGYARGEGCGAVLLKRLSAAQADGDTILAVIRGSAIGQDGASSSFTAPN
                     GLAQQQVIRRALADAGLTPGDVDYIEAHGTGTPLGDPVEVSAYCGVYCDGRSSDRPLLL
                     GSVKANIGHLEGAAGMASLLKVILALRHKRIPPQPAFGAPNPLIPWDKVPLQVIKESTC
                     WETFAAPRRAGVSGFGFSGTNAHMIVEEAPA"
     CDS_motif       complement(8784..8828)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_2_0009"
                     /evalue="1.10E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="ctg4_2"
                     /protein_end="808"
                     /protein_start="793"
                     /score="11.5"
                     /tool="antismash"
                     /translation="GSVKANIGHLEGAAGM"
     CDS_motif       complement(8889..8936)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_2_0008"
                     /evalue="3.10E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="ctg4_2"
                     /protein_end="773"
                     /protein_start="757"
                     /score="12.9"
                     /tool="antismash"
                     /translation="YIEAHGTGTPLGDPVEV"
     CDS_motif       complement(9129..9167)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_2_0007"
                     /evalue="4.80E-03"
                     /label="PKSI-KS_m4"
                     /locus_tag="ctg4_2"
                     /protein_end="693"
                     /protein_start="680"
                     /score="10.3"
                     /tool="antismash"
                     /translation="FEAAANGYARGEGC"
     CDS_motif       complement(9309..9356)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_2_0006"
                     /evalue="2.30E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="ctg4_2"
                     /protein_end="633"
                     /protein_start="617"
                     /score="19.5"
                     /tool="antismash"
                     /translation="GPNISVDTACSSSLVAL"
     aSDomain        complement(9918..10064)
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg4_2_ACP.1"
                     /evalue="3.90E-16"
                     /label="ctg4_2_ACP.1"
                     /locus_tag="ctg4_2"
                     /protein_end="430"
                     /protein_start="381"
                     /score="50.9"
                     /tool="antismash"
                     /translation="HTGFFDLGVDSLTSIRMVRELEAKIGISLPVTTLFDYTSPDALAK
                     HLLTL"
     aSModule        9918..11189
                     /domains="nrpspksdomains_ctg4_2_PKS_AT.1"
                     /domains="nrpspksdomains_ctg4_2_ACP.1"
                     /incomplete
                     /locus_tags="ctg4_2"
                     /tool="antismash"
                     /type="pks"
     aSDomain        complement(10305..11189)
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg4_2_PKS_AT.1"
                     /evalue="4.10E-91"
                     /label="ctg4_2_PKS_AT.1"
                     /locus_tag="ctg4_2"
                     /protein_end="301"
                     /protein_start="6"
                     /score="297.2"
                     /specificity="Minowa: mmal"
                     /specificity="consensus: pk"
                     /specificity="PKS signature: Malonyl-CoA"
                     /tool="antismash"
                     /translation="IYSGMGAQWKAMGQQLFRTNELFRRQVEELDPAIQQYTGFSVVEE
                     IVRDKEASRLNAPWIAHPVAFAVEIGITSLLASWGIVPEAVIGHSGGEVVAAYVAGLLS
                     LEDAACLLGAHSRAMRQVEGKGGMLFVGLPFRQVEELIAPFHPDLSIAAINGPRSTVVS
                     GLSGMEGFISLLKEQKVFHRVIPTDVAFHSPQIEPALEEFRHAIDKLSPRPARMPIYSS
                     FRGQLAAADDFGSSYWVRHIREQVRFAQAIAAMLADGYRLFVEVAPHPLMQTSLMECFA
                     EAGVKAHAMGTLVRD"
     CDS_motif       complement(10446..10481)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_2_0005"
                     /evalue="2.90E-03"
                     /label="PKSI-AT-M_m8"
                     /locus_tag="ctg4_2"
                     /protein_end="254"
                     /protein_start="242"
                     /score="11.2"
                     /tool="antismash"
                     /translation="YWVRHIREQVRFA"
     CDS_motif       complement(10698..10736)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_2_0004"
                     /evalue="1.20E-04"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="ctg4_2"
                     /protein_end="170"
                     /protein_start="157"
                     /score="15.3"
                     /tool="antismash"
                     /translation="AAINGPRSTVVSGL"
     CDS_motif       complement(10854..10952)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_2_0003"
                     /evalue="1.80E-13"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="ctg4_2"
                     /protein_end="118"
                     /protein_start="85"
                     /score="42.6"
                     /tool="antismash"
                     /translation="GIVPEAVIGHSGGEVVAAYVAGLLSLEDAACLLG"
     CDS_motif       complement(10965..11006)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_2_0002"
                     /evalue="5.90E+00"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="ctg4_2"
                     /protein_end="81"
                     /protein_start="67"
                     /score="1.0"
                     /tool="antismash"
                     /translation="HPVAFAVEIGITSLL"
     CDS_motif       complement(11142..11192)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_2_0001"
                     /evalue="6.10E-04"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="ctg4_2"
                     /protein_end="22"
                     /protein_start="5"
                     /score="12.6"
                     /tool="antismash"
                     /translation="FIYSGMGAQWKAMGQQLF"
     CDS             complement(11224..12825)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1053:beta-lactamase (Score: 157.2; E-value: 9.2e-48)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_3"
                     /transl_table=11
                     /translation="MQQIRKRTKLLALWTGLILLLSISGCGNTDYISGDVGAPPPVTQK
                     TQAALKAAVDDYMQYVGTPSGVPGTIVAVKMNGYQPWYYAYGSAEIALPNNPGSAFTQK
                     TAMDAGMPFRIASITKMFIAQAVIQLAQEGKIDLDQTVENYLPGALTGKNLANKDKITI
                     NMLLNHTSGLYSYVTSDAGLLHGNLPTAAGTTGLRLLPMDTFVEGLGLTAWSHSYSPQD
                     TILQFANTFSPPLSLVDTITGAIGNPYGSNPYFAPGTDLHYSNTNYYLLGLLIQKIATQ
                     YETDPAKQTVEYQIKRLITDPLKLSDTYLPTTKTFNNPVHVHGYADYFNSEAYRTAMSD
                     NLLKFSACQNNSAWCTGDGILEDFTEIDPSFAWTTGGMISSAKDLLTFAQFVTQTRVQT
                     GQEAGKWINGSPLDNSTTFQYGRGIARINNVMFGHGGQFAGYNVAVYWYAPLDIYFMVM
                     TNKYSYTENDPNDLGGSIVAGADSMYALSVKQTTAAPVDHNRSIINSLITALEQDPNVA
                     KKGATPVRLSSYFLEM"
     CDS             complement(12854..14023)
                     /locus_tag="ctg4_4"
                     /transl_table=11
                     /translation="FRTNSYLVNELIDWDNVETDPIYRLNFPCREMLLPDHYKRISALI
                     ECGASREKLREAVWKIRHELKPQSVHALDGTLASLNGRKQQGIVHIYPETVLFFPAEGQ
                     MCHAHCTFCFRWLQFVGEEEEIFASMDVNALISYVAQHEEVRDILITGGDPLFMRLDTL
                     SNYVDRILAADIPHLKNIRFGTKTISYWPYRFLTDPGAEALLKLFEKIITKGKHVAVMA
                     HINHPRELATEAAQRAVARIRATGAEIMSQSPLLRHINAAPEIWTELWQEQVRLGIVPY
                     YQFIVRDTGARHYFGVPLVEALEIFRAAYRKVSGLCRTVRGPVMSLPQGKVQVLDVHEC
                     AGEKGILLHHIQAPDQNRVLKTFFAVYDERAQWFTDLKPLRPVDAGFFH"
ORIGIN
        1 ggatcaccgg ggtattggcc aaggacattc agaacatccc ggaaattgag acccaccgcc
       61 ctaacctgca cctccacctc gccgggttct ggggcaacgc ggccgcgggt tcttacacag
      121 agaccctcca ggctccctcg ctgatcgacg tcgatgtaaa agccatcttt tttcggcaga
      181 atcatcccct ttgacagttc ctgtgattct gcccggcaga gtcggggcac aaaacgccgt
      241 ctcccgcgca gcgcgacacg gtcctcgcca tcacgtacgg ccagttcatt cacgaattgt
      301 gcgccttcgt cctttcccgg ccagggggag agatccagca gtctgcaaga caattcggga
      361 tgttcggctg cgacggtagc gccaaagccc cagaggggcg caccctccgg tctgttttcc
      421 cgatccatgc ctgaagggtt gtgcacaccc gcagtgacca ggaaaagcgg gacagaaatc
      481 tttgccgcca gcagtccctt cacgagattc agatttcccg tcagatcctc cccccaaaac
      541 gagactagtc cggcaacagg ttccgggctg tttcgcaagt caagagcaag actttccata
      601 tcttccggag agaacggatc aacggcgatg cgaccttcct tccccccctc actgcccgcc
      661 tttacgacct cagtgagact gacgccgcat cccttgagga cctcagatag ggcggcggca
      721 cagggcgatg ggtctgtcag cgccacccat cgcccggaga gagaggatgc gggcgcggca
      781 ggcgcgcact cccgccagag gacctggtac atcaggtcgg aaagaacggt agtgctcctc
      841 gacagcattt gctctttcct gattctcctg agggtgaggc cggtgatctg cagcactggc
      901 gcaccgtcgc ggtcagtggc gatgagatcg aacctcgcgc tggcttggct tctctcttgc
      961 tggacacaac gcacctgcaa gcaggaagcc tgcgcgccgg aaaaaagcag ggaatcgatc
     1021 tctgccggca cgaatgccac tgcgtccggc aagggttccg gaccatagag aaacgatgcc
     1081 ccggtcaggg tcaggcagcc gtccagcaag gcggggtgca ttacaaaacc cgccgccgcc
     1141 tcttgcggga tttccacatc accggaaatg tgagcaccac aaaatcgaag acgccggatg
     1201 ctccggaaaa cgccggtata gcagtaccct ttctccagca agtcgctgta atagcgatcg
     1261 ccgtccaccg cgataccacc ctcatcattg ctcttctcct ttcccgccag ggcttgtctc
     1321 gccacagagg acattccctc ctctttctct ccgccagccg cagggaattg aggggcgagg
     1381 ctcccttgca gaggaggata ggaaactttt tggccagaga ggggacggac ggtcagggaa
     1441 gcgtgcagct gccattgccc ctgggaggca agactgaaga cctcgacggc tccggtatcg
     1501 ggccggtaga tggtttgtag gctcttacgt tcttccgtaa gaagcagcgg cattgcaaac
     1561 ctggcttttt ccaacagaag cggcgctgcc ggaagaaact gtgggactgc tgaggccagg
     1621 gccatctcca gataagcggc agccggcaca atcacagcgc cgtggataac atggccagcc
     1681 agccagggat catccgtcgt cccaagagca ccgacaaaac gtttctctac agacggagca
     1741 tccatgcgac ggcccagcaa cggatgctcc tcgcccatca aggagatccc cttagccgta
     1801 cccctgccgc caggctcatg gaccggatcc atgatataac gctcgcgctg aaagggatag
     1861 gtcggcaggg aaactcttcc cgcacgatag ggagcatcaa acccctgcca gtcaatggcc
     1921 acgccggcgg caaataagtc gcccaaggcg gccataaggg tagaccaggg tggaactctt
     1981 cgtttgaggg aagcaaccaa gcggcaatcc gccccggcta tctggcggac gaaggaggaa
     2041 agggtagcgg ttgcaccgac ctccagaaaa aggtcatgac cctgcttatt cagaaactcc
     2101 accgactcgc tgaaccgtac cgagccgcgc agatgacgcc gccagtaaga ggctgtccgc
     2161 aggtcatcgc ccacggccgg tttacccgtc acattggaga tgacggtcag agtcggctcg
     2221 tggaaggtca gggaggcagc aatcccttca aactcttcca gcacgggatc catcaggggg
     2281 gaatggaagg catgagaaac gttcaggtat tgggaggaga atccctgttg ctgaagcgtt
     2341 tccaaaaccc ctgcgacccc gacccggtct cccgagataa ccacggatcc aggcgaattc
     2401 accactgcca gcgacacccg accggcatgg ggggcaagcg ccggcaatat ggcagcctcg
     2461 gaacaacgca ccgccgccat cacccctccg gcaggaaggg cattcatcag ccggccccga
     2521 tgcgccacca gggttacggc atcttccagg gcaagcacgc cggcaaggca ggcggcgaca
     2581 aattcgccga tgctatgccc cacaaccgct gacggcctga cgccccagga gctccagaga
     2641 caggccaggg aatattccag gctgaagatg gccggctgag catatatggt gcaggccaat
     2701 tgttcctcgc tgtcgccatg catcaggtcg cggatggaaa gaccgataag cggtgcaaaa
     2761 agggaatcgc aacggtcgag ggcttcccga tacaccggcg aagtggcgta caactcccgc
     2821 cccattcctg gatactggga tccctggccg gtgaagagaa aaaccgggct gggtttttct
     2881 ctggactggg aagaacgcag gtaaattcct ttcgtggttc cttgctcaac aaaggcggat
     2941 aaacgctcag ccagctcggt ggacgtgttg ccgacgaccg ccagaccgtg ggaaaacgta
     3001 ttcctgccgc tggcggcggt atggcaaatg gcggccaacg gcgggagagc agggccttgc
     3061 aggtaggtgg cataacggcc ggccagggag cgcagcgcga cttcaccggc agcgctgatg
     3121 gccagaagat ggctggtgcg tccatctgcc ggaggaaaag cattgagcgg cgcctcctcg
     3181 agaatggcat gggcgttggt gccgctgaag ccgaaacagc taatgccggc ccgtcgggga
     3241 cgggaagaac ggctccagga tgcgccgccg gaaacgatgg agagcggcag gcggtcccag
     3301 gcgacgtggg gattgggagt attaaagtgg agatgggagg ggatcttctc gtggttcaag
     3361 gccagcacca gcttgatcac accggcaatg ccggccgccg cttcgaggtg gccgatgttg
     3421 gtcttgaccg agccgaccaa gagcggatgg tccggatctc gcccctgacc aagcaccgca
     3481 gcaatagcct cgatctcgat ggggtcaccg agggaggtgc ctgtcccatg ggcctcgaga
     3541 taatcaatat ctccaggcat taaggcggca tcctccaggg cggcgcgaat cacccgtcgc
     3601 tgggccatgc cattgggggc ggtcaagcca ttgctccggc catcactatt cagggcactt
     3661 cccctgatca ccgccaggat ccgatcgcca tctttttcag cagcgtccat ccgcttcagg
     3721 acgatcatgc cgcatcctgc cccccggccg taaccgttgg cgtcggcgtc aaaagtctta
     3781 cagcggccgt cgggggaaag ggcccgcagc ttgcagaagg cgatcagcgg ttccggcgtc
     3841 agcatcagat ttacccctcc caccagggcc atttggcatt cacggttgcg cagcgaccgg
     3901 caggccagat gcaacgccac cagagacgag gaacaggcag tgtccaccgg aaagtttggg
     3961 ccttcgagtc ccagaaaata cgatatgcga ccggcagcgg tactgaaagt gaaccctgtc
     4021 agggaatagg gatcaatcag ggatggatcc ccggaacgga gatgggcgct gtcgtagtca
     4081 ttacttgaaa taccgatgaa caccccggtg cggcttcctt gaagcgaggc aggattgatg
     4141 cctgcatcct ccagagcttc ccaggcagtc tcgagaagca gcctctgctg cggatccaga
     4201 gacttcgcct ctttgggtga gatcccaaag aaaggggcat caaaatcgta aggataaaag
     4261 tccagaaaac caccttcccg gacatacatc ctcccgggcg aatcctggtc atgagaaaag
     4321 taatgtcccg cagaccaacg ttttgcaggt atgggagaaa tggcatccct cccttccgct
     4381 aaaaggcgcc agtattcttc aggtgagttg gcgccgccgg gaagacggca tcccaagccg
     4441 atgatggcga tcgattcgcg gcgcttaagc cgttcatttt cggtaatgag ctgctttatg
     4501 gtggaagatg cctttttcag cgcatcttgg tacgtggtca catcagacat atcttatcct
     4561 ataagctctt tcagttctgc caacagatcc cgtgcagtgt cggcaagttc cggagttctg
     4621 atatccggag ccgcgacgga aggggatagg gcgagttgat cggcaagcag atggccggcc
     4681 aggctatcga gggacgggaa attgaacagg gtggcaaccg taagattggc tcccaaatct
     4741 ttgacgagta cattgcgcag gtcaaccatc atcagtgaat ctaaacccaa ttccaccagc
     4801 ggggctccga tgtcaaggcg attaacaggc aaaccgatca cctcgccggc ccgctgctgc
     4861 aggtggcgcg tcagaagcgc tctgcgggca gcaggatcgg cctcctggag ttctcttaag
     4921 atcggggaac ggtcctcaac ttcaagcggg gaatgctgcc gcgaggtgag tccggacaac
     4981 aaaccgccgg gagagagccg gtaaaattcc tggtaacggt cccaatcgca acgcaccgca
     5041 gcgatgcacg ggtatggggc acggcacgcc tgttccacta tcggcagcac tgtttctgcc
     5101 aaaatatagt tgaacccctg ccgctcaacg agtcgcttca ccgtatcgga cgactccgcc
     5161 attcctccac cggagagcgg gccccaggca atactgaggg ccggttgtcc ctgagagcgg
     5221 cgccatccgg aaaggccgtc cagaaaggcg ttggcggcgc agtaggcccc ctgcccacga
     5281 ttgcccagca ccccggcggc agaagaaaaa agaacaaagt ggtcgagttt taggccggca
     5341 cagagccggt gcaaatgcca ggcgccggct gctttggccc cgagagagcg gcgcagtcgt
     5401 tccgcatcca gagaggcgag cggggcatca tcaaggactc ctgccagatg aaacactccg
     5461 gccagacggg gcatggttgt ttgcatgacc gccaacagtc gttccacctc cggccctgaa
     5521 gaaacatcgg ccttcataaa agtgacagcc gccccggcag atgccaaggc cgcgatccgt
     5581 tccgccgcct cccctgccgg tacgtgacgt ccggaaaggc agagatgctt cactcccgct
     5641 gtgaccagcg actccgccag tgccaaccct aatgcaccgg cgccaccggt aatcagatag
     5701 gaggcgtcgt tacaaaacag agggccgctc tcgcctggca cggataaatg ctccattctt
     5761 gggcaataaa ggttgccacc cctcagggca atctcgcgct cacttcccgg atcggccagg
     5821 aaggagatca gttttgacaa tgccggaaaa gaaaaagcgg tgtcatccag gtcgatgatg
     5881 ccaccccata tctcaggata ttccagtgca gcggcgcggc ccaggccctg acaggccgct
     5941 tgcaacgggt tgggaggcgg tccggatgcg gcagccgccc gctgagtgac aagccagagc
     6001 tttgcccctg cggtatgatg gaatcgctcc gcgagtccgg caatcaggga ggacaggccg
     6061 gcaagttgct cgggcaatcc catcatgcct gattcaggtt cggcgaggga cgcagcgagc
     6121 aaaatcgtca gcgcctcccc gttcttgccc catgtttggg tttcgcttag cgccgctttg
     6181 ggagatagag aggttgagga atgccccagg gaactgatcg ctgtggaaat ggatcctgcc
     6241 acggcgtctt cgccgatgac cagatagcgc ccctgtgcga cctcttggct gctctcgggc
     6301 agcgccttcc agttgagatg atagagcagt ccctctgtcc tctccgtggc atacatggtc
     6361 ttccggtcgg tacgacgcag actgaagccg ctcactgcca tcaagagcgc cccctctgcc
     6421 gaatagaccc gcacctgtga ttcgatggca tctgctgttg ttagggcgcg ggagtgacac
     6481 cagatctccg cgcccagagg ggcgacaaac acaacttcct gcgcccctac ggggatatag
     6541 atccgctccc ccccttcaat cgcctgtcga aactcctgag atgtcgcacc catactgtgc
     6601 aggatggcat ccatcaggcc ggggtccggg tcggcgggat gggcaacccc ttccaggcgg
     6661 cagagggatt caccatcgcc ggccaggatt tccttgatcc tttggtagga aggacctact
     6721 ttataacctg cggcgagaaa ggcggcgtag aactccgccg gatcgagctg ccgggtgcag
     6781 cgctttctga tgagagcaaa cggctccgct tcggggatag ttaccccgga aaaggccgaa
     6841 ccaaggcaat gctcctgcca gtggggagcc ctttcatctc tataccggct gacgatcctg
     6901 agcgaacgaa cgccggctga aggggcgctc accagtacct gcacatttcg tccttcctga
     6961 ccaaccaaca ggggtcgaac aaaatggacg tccctcagca tgaccggcag ggagggatcg
     7021 tctgaaaccc cgcgcattgc cgcagccagc atgcaaagat gggccgcggc cggcgacagc
     7081 acgcggtcaa agatcacatg ttcggcaaga aaacggggag tcgcaggggt aaagagggtc
     7141 gaatagatca ctccctcccc gagagccggg gaatcgatcc gctctcccaa caaggggtgg
     7201 ctgccggagg gcgccgccgc ggtggcagaa agcagcggtt cagtccagta ggaggcacgc
     7261 tggaagggat aggcgggaag ttgtaccgtc cgccgctcac atccgctgta gtaagtacgg
     7321 gctgaggcaa ctccccgttc cgccaacata cacaagctgc ccgcgatctg tctgaggtcg
     7381 tcgtggccgg gacggaggct gggaagccag gcgtgcccag gatcggcgga aatggtcttg
     7441 ccgaaggccg acagaatagg cgctgcgcca atctcgacaa aggcggcgta cccctcctgc
     7501 agcagtgtct ccagggcggc gccaaaacgg accggctctc gcaactgacg ccgccagtac
     7561 cgaggcgagc agcaatcgtc gcctgtggca acctttcccg tcagtccgga caccaagtcg
     7621 atgcgggctg aagaggcgcg gacggcagcg gccgcctgtt caaacggttc gagaagcgga
     7681 tccatcagcg gagagtggaa ggggtgagat accgagagat accttggccg cttccccgtc
     7741 agttccagct ggccggcgat ctgcctcacc gcctcactct cgcctgagat cactacactc
     7801 cggggggtat tgagagcggc gatggccacc ttgtcggccc gagcggccac cagcggcgca
     7861 acctccgctt cggtagcatg gaaagaaacc atcaagccgc cacccgggag ggaatccatc
     7921 aaggcggagc gacgggcaac cagatatacg gcatcttcca gggagagcac gccggccaga
     7981 caggcagcgg caaactcgcc gatactgtgt ccggcggcag cggccggccg gatcccccag
     8041 gactcccata gtttgtacaa ggcgtactgg agagagaaga tggcgggttg ggcgtggcgg
     8101 gtactagcca gcagtgcttc atcatcgcca tgcatcagct cccggatcga tcgccccaaa
     8161 tagggggaaa aaagccgatc acagtggtcg aggacctctc gataggccgg ccaggcgttg
     8221 tacagacctt ttcccatacc tgggtactgg gatccctggc cggtaaagag aaatacgacc
     8281 cctttgtctc gggcggacgt cgttgtcgcc aatcctctgg ccaggcgttt tttcaggctt
     8341 tcggccagtt cagcagccgt gcgtccggca accgcaattc gttcgggaaa gccggggcgg
     8401 ccaaaggccg cagtagcaca aatgtcggcg ggcgaagcgc tggcagcccg aagcaggtcg
     8461 agatagcgct cgccaaggtc ccgcagggcc tcgggtgtgc gggcagaaaa gacaagcatg
     8521 tggcacggaa gttcctgtac tgaggcatca accggcggag ctggcgcctc ctcgacaatc
     8581 atatgggcgt tggtgccgct gaaaccaaaa ccgctcaccc ctgccctccg cggtgccgca
     8641 aaggtctccc agcacgtgga ttccttgatc acctggagcg gcaccttatc ccaggggatg
     8701 aggggatttg gcgcgccgaa tgcgggctga ggaggaatcc ttttatggcg cagggccaga
     8761 atcactttga gaaggctcgc catccctgcc gcaccttcca ggtggccgat attggccttc
     8821 accgaaccaa gcagcaaggg cctgtcggaa gagcggccat cgcagtaaac tccgcagtaa
     8881 gcggacacct ccacaggatc gcccaagggg gtaccggtcc cgtgggcctc tatataatcg
     8941 acatccccgg gcgtgagtcc ggcatcggcc aaagccctgc ggatgacctg ctgttgcgcg
     9001 agaccattcg gtgcggtaaa gctggaactg gccccgtcct gaccaatggc gctgcctctg
     9061 atcacagcca ggatggtatc gccgtccgct tgggcggctg agagacgttt gagcaggact
     9121 gccccacacc cttcgccccg ggcgtaacca ttggccgccg cctcaaaaga ccggcaacgc
     9181 ccgtcaggag agagcgcccc cagtttggaa aaatagacaa aattgtgcgg cgtcacaagc
     9241 aggttaaccc cggcggccag ggcaacatcg cactcgtcgc gccgcaggcc ctggcaggcc
     9301 agatggagcg ccaccaaaga ggaggaacag gccgtatcca ccgagatatt aggtcctgta
     9361 aaatcaaaga cataggatat tcttccgccg gccgaactgg ccatggaacc ggacccggaa
     9421 taggagtcga tacggtccat actgccggaa tggagatggg cggtcttgta gtcatcgctg
     9481 cagatgccta aatagacgcc gacgttcttt cccttcaacc catcgatcgg aatattggcc
     9541 tgctccatgg tctcccagac tacctcaagc aggatgcgct gctggggatc aatcgcccga
     9601 gcttcacggg gagggatacg aaagaagggg gcgtcaaaga ggtcaagccg gtcagggatg
     9661 agaaggcccg cctccttggt atagctcgtg ccgggttttt ccggatctgg atcataatac
     9721 acgcccgggt cccagcgggt gaccgggatc tctcgcatgc ccgttcttcc ctggtctagc
     9781 aagtcccaaa actgctctgg cgaatttgct cccccgggga aacggcagcc cattcccacg
     9841 acggcgatag gttctttcca gccaagaggg ctgtctttcc ttgacgtagg ttccagtttg
     9901 ccctcgccgg caagaagcgt gagcagatgc ttggcaaggg cgtcgggaga ggtataatcg
     9961 aagagggtgg tcaccggcag agagataccg atctttgctt ccaactccct taccatccga
    10021 atgctcgtca gggagtcgac acccagatca aaaaaaccgg tatgttcgtc ttcaatcttc
    10081 aatttattgg aactcgccac agcgagtgcg tcgctgatca gacgcaagat agcggtaggc
    10141 tccggaagcc gtgactttga aggggatggg cctgacaaag gatggggccg cagcatctcg
    10201 acagtacgtc gctcctctcc gctcaatcgg tcccaggcca cgggcaagcc actcttttca
    10261 aggtcaatca gggtacgcag caggtcatca atactgccgg aatcccgcac cagggtcccc
    10321 atggcatgcg ccttgactcc tgcctcggca aagcattcca tcagcgaggt ctgcataagt
    10381 ggatggggcg cgacctccac aaaaaggcga tatccatcgg cgagcatggc ggcaatggcc
    10441 tgggcaaacc tcacctgttc cctgatatgg cggacccagt acgaggagcc gaaatcatcg
    10501 gctgcggcta actgacccct aaaggaagaa tagatcggca ttcttgccgg acggggggaa
    10561 agtttgtcta tggcatgccg aaattcctca agagcaggct ctatttgagg gctgtggaaa
    10621 gcgacatccg ttgggatgac gcggtgaaat accttctgtt ctttcaatag tgagatgaat
    10681 ccctccatgc cgctaagacc tgaaactacg gtggaacgag gaccattgat ggccgcaatg
    10741 gagagatcgg gatggaaagg ggcaatcaat tcttccactt gccggaacgg gaggcctaca
    10801 aaaagcatcc ccccctttcc ctctacctgg cgcatggctc gactatgggc gcccaaaagg
    10861 caggctgcat cctccagaga aagcaacccg gcaacataag ccgcgactac ttcaccgccg
    10921 ctatgaccga ttacagcttc cggaacgatc ccccacgaag ccaacaggga ggtaatgcct
    10981 atctcgacgg caaaggcaac cggatgggct atccaggggg cgttaagacg ggatgcttct
    11041 ttatcgcgta caatttcttc tacaactgaa aaacctgtgt attgttgaat ggcagggtcg
    11101 agctcttcca cctgccggcg gaagagctca ttggtcctga aaagctgctg tcccatggcc
    11161 ttccattgag cgcccattcc tgaatatata aaggacattt tgaccatgga ttgtctcttg
    11221 ccttcacatc tcgaggaaat aactggaaag ccgaacaggg gtagctcctt tttttgccac
    11281 gtttggatcc tgctccagag cagtgatcag gctgttgata atggagcgat tgtgatcaac
    11341 cggagcagca gtcgtctgtt ttaccgacag cgcatacatg gaatcggccc ccgctacaat
    11401 tgaccccccg agatcattgg gatcattttc cgtgtaggaa tacttatttg tcatgaccat
    11461 gaaataaata tcgagagggg cgtaccaata gacagccacg ttgtatcctg caaactgtcc
    11521 gccatgacca aacatgacgt tattgatgcg cgctatacct cgtccgtact ggaaagtcgt
    11581 ggaattgtcc agcggcgaac cattgatcca tttccccgct tcctgtccgg tctgcacgcg
    11641 tgtttgcgtg acaaactgcg caaaagtcag caaatctttg gcgctggaaa tcatgccccc
    11701 ggtagtccag gcaaaagagg gatcgatttc ggtgaagtct tccaggatgc catctccggt
    11761 gcaccaggca gagttgtttt ggcatgcact gaacttgagc aggttgtcac tcatggctgt
    11821 tctgtaagct tcactgttaa aataatccgc ataaccatgc acgtgaacag gattgttaaa
    11881 ggtcttggtt gtaggcaggt aggtatccga aagtttgagc ggatcggtga tcaaccgctt
    11941 tatctggtat tcaaccgttt gcttggcagg atctgtttca tactgcgtgg ctatcttctg
    12001 gatcagaagt cccagcagat aataattggt gttggaatag tgtaaatccg tccctggagc
    12061 aaagtagggg ttggagccgt aagggttgcc gattgcgccc gtgatcgtat ccacaaggga
    12121 tagagggggg ctgaaggtat tggcaaactg cagaatagtg tcctgaggag aataggagtg
    12181 ggaccaggcg gtcagcccca ggccctcgac aaaagtatcc atggggagga gccgaagtcc
    12241 cgtcgtgccg gcagccgtag ggaggttacc atgcaagaga ccggcgtccg aggtaacata
    12301 actgtaaaga ccgcttgtat gattgagaag catattgatg gtaattttgt ctttgttggc
    12361 caggtttttc cccgttaagg cccccggcag ataattttcc accgtctgat caagatcgat
    12421 cttcccttcc tgagccaact gaatcactgc ttgggcgatg aacatcttgg taatgctggc
    12481 gatgcggaag ggcatgccgg catccatggc tgttttttgc gtaaatgcag aaccgggatt
    12541 gttcggcaat gcaatctcgg ccgagccgta agcataatac catggctgat aaccgttcat
    12601 tttcacggcc acaatcgtgc cgggaacgcc ggacggcgtc cccacatact gcatgtaatc
    12661 gtccacggct gccttcagag cagcttgcgt tttctgtgtg accggcggag gggcgcccac
    12721 gtcacctgaa atgtaatcgg tgttcccgca tccactgatc gacagcaaga gtataagacc
    12781 tgtccacaac gccagcagtt ttgttcgttt tcggatttgt tgcatatgta agcctccttt
    12841 aaggaaatgt aatctagtgg aaaaaacctg catccactgg ccgcaacggt ttcagatctg
    12901 taaaccattg cgcccgttca tcatagacag caaaaaaggt cttaagcacc ctgttctgat
    12961 caggcgcttg aatatggtgg agcaggatcc ccttttctcc ggcacattca tgaacgtcaa
    13021 gcacctgcac tttgccttgc ggcaacgaca taacaggtcc gcggaccgtc cggcagagtc
    13081 cgcttacttt gcgataggcc gcccggaata tctccagggc ctccaccaga ggcacgccaa
    13141 agtaatgccg cgctccggta tcccggacaa taaactggta ataggggacg atgccgagcc
    13201 tgacctgttc ctgccagagt tccgtccaaa tctcaggggc ggcgttaata tggcgcagca
    13261 ggggagactg ggacattatt tcggcgcccg ttgcacggat gcgggcgaca gcccgctgtg
    13321 cagcctccgt cgccagttcc cgggggtgat tgatatgtgc cataacggcc acatgctttc
    13381 ccttggtaat gatcttctca aacagtttca gcagcgcctc tgcaccagga tcggtgagaa
    13441 agcggtaagg ccagtaggaa atcgtcttgg tgccgaaacg gatgtttttg aggtggggaa
    13501 tgtccgccgc cagaatccga tctacataat tagagagggt gtctaatctc atgaacagcg
    13561 gatcgccccc ggtaatgaga atgtctcgca cctcttcatg ctgcgctaca tagcttatca
    13621 aggcattcac atccatgctg gcgaatattt cttcttcctc ccccacaaat tgcagccaac
    13681 ggaagcagaa ggtgcaatgg gcatggcaca tctgtccttc ggcagggaaa aatagcaccg
    13741 tctcaggata gatatggaca atgccctgct gtttccgtcc attgagggaa gccaacgtcc
    13801 cgtccaatgc gtgcacggat tggggtttca actcatgacg gattttccac accgcctcac
    13861 gcaatttttc cctggaggcg ccacactcta tcaaagcgct tatccgctta taatgatcgg
    13921 gaagcagcat ttcgcgacag gggaaattca ggcgatagat cggatccgtt tccacattgt
    13981 cccagtcgat caattcattc acaagatagc tgttggttct aaa
//
