LOCUS       c00044_3300014..        3677 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300014786.a:Ga0169450_109086.
ACCESSION   c00044_3300014..
VERSION     c00044_3300014..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 08:11:54
            Original ID  :: 3300014786.a:Ga0169450_109086
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 3677
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..2481
                     /NRPS_PKS="Domain: PKS_AT (249-528). E-value: 4.5e-90.
                     Score: 293.7. Matches aSDomain:
                     nrpspksdomains_ctg44_1_PKS_AT.1"
                     /NRPS_PKS="type: PKS/NRPS-like protein"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     hyb_KS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1021:malonyl CoA-acyl carrier protein transacylase
                     (Score: 261.1; E-value: 3.8e-79)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg44_1"
                     /sec_met_domain="PKS_AT (E-value: 2.7e-91, bitscore: 293.7,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="hyb_KS (E-value: 2.4e-55, bitscore: 175.7,
                     seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="INNDGAQKVGFTAPSIKGQAQVVAEALALAEVEPSMVGYLETHGT
                     ATNLGDPIELAALKKVFGATAAQAWCALGTLKANIGHLDNAAGVAGLIKTALALHHRQR
                     PPTAYATIPHSNLQQSPFYLNPTASAWDANLYAGVSSFGIGGTNAHVVLAAAEPIAKQA
                     QAESWQLLPISAASVWSLEQQTERLAAHLQTNPAQSLADVAYTLQTARQAFAQRSFVVA
                     KSHEQASQALLTSPIREFASQPPKVAWLFSGQGSQCAGMAAELYQQAPAFRQAIDLVNR
                     YAQPLLGYDLRQMMFDHSGDLTATNVAQPCLFMLEYALAQQWLAWGIQPQALFGHSIGE
                     YVAACVANVLDLPTAVRLVVVRGQLMNQLPSGAMLSINASRDQIQPILPAELDLAAINT
                     NQLLVVAGEHVAIQAFQQQLNERGIESRILHTSHAFHSRAMQPMLAAFRQHFADVQLQA
                     PTIPILSNVSGTWLTAVQATSVDYWLEQIVNPVQCAACLAQLLADDAWIVQELGPGHTL
                     ATFARASQAAQTPLILTSLPHPQVKQADLAVMLQSLGQLWQAGMTVLWQALHQTSCHKV
                     WLPTYAFDHQRHWIEAEQAHAPRASNQISINTPTWQAQSLATTPIQASTWLVWGSQPST
                     IERLLEQFAADQQLYICNQDTFXXXXXXXXXXAADLLTIAKRVRELGLAQVHLHVVSSQ
                     SLAIAPHEDLNPHDAALRGVAMVLAQEYPEISSHWLDLDFTHQAWPSMLAQELQSASEP
                     VVALRGFNRFVPQARVASLPTNQQGFLVGGCYLITGGNGGLGRQIAXXXXXSCLSRPLP
                     MICNSRLPNVVVRP"
     protocluster    1..3677
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[0:2481](+)"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1..2481
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
     cand_cluster    1..3677
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="single"
                     /product="T1PKS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..3677
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T1PKS"
                     /region_number="1"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /tool="antismash"
     CDS_motif       115..162
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg44_1_0001"
                     /evalue="1.50E-03"
                     /label="PKSI-KS_m5"
                     /locus_tag="ctg44_1"
                     /protein_end="54"
                     /protein_start="38"
                     /score="11.1"
                     /tool="antismash"
                     /translation="YLETHGTATNLGDPIEL"
     aSDomain        748..1584
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg44_1_PKS_AT.1"
                     /evalue="4.50E-90"
                     /label="ctg44_1_PKS_AT.1"
                     /locus_tag="ctg44_1"
                     /protein_end="528"
                     /protein_start="249"
                     /score="293.7"
                     /specificity="consensus: mal"
                     /specificity="Minowa: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /tool="antismash"
                     /translation="LFSGQGSQCAGMAAELYQQAPAFRQAIDLVNRYAQPLLGYDLRQM
                     MFDHSGDLTATNVAQPCLFMLEYALAQQWLAWGIQPQALFGHSIGEYVAACVANVLDLP
                     TAVRLVVVRGQLMNQLPSGAMLSINASRDQIQPILPAELDLAAINTNQLLVVAGEHVAI
                     QAFQQQLNERGIESRILHTSHAFHSRAMQPMLAAFRQHFADVQLQAPTIPILSNVSGTW
                     LTAVQATSVDYWLEQIVNPVQCAACLAQLLADDAWIVQELGPGHTLATFARASQAAQT"
     aSModule        748..1584
                     /domains="nrpspksdomains_ctg44_1_PKS_AT.1"
                     /incomplete
                     /locus_tags="ctg44_1"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       751..798
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg44_1_0002"
                     /evalue="1.70E-05"
                     /label="PKSI-AT-M_m1"
                     /locus_tag="ctg44_1"
                     /protein_end="266"
                     /protein_start="250"
                     /score="17.3"
                     /tool="antismash"
                     /translation="FSGQGSQCAGMAAELYQ"
     CDS_motif       913..969
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg44_1_0003"
                     /evalue="2.00E-03"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="ctg44_1"
                     /protein_end="323"
                     /protein_start="304"
                     /score="11.5"
                     /tool="antismash"
                     /translation="TNVAQPCLFMLEYALAQQWL"
     CDS_motif       979..1101
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg44_1_0004"
                     /evalue="2.20E-23"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="ctg44_1"
                     /protein_end="367"
                     /protein_start="326"
                     /score="74.6"
                     /tool="antismash"
                     /translation="GIQPQALFGHSIGEYVAACVANVLDLPTAVRLVVVRGQLMNQ"
     CDS_motif       1627..1677
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg44_1_0005"
                     /evalue="1.60E+01"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="ctg44_1"
                     /protein_end="559"
                     /protein_start="542"
                     /score="-0.3"
                     /tool="antismash"
                     /translation="QADLAVMLQSLGQLWQAG"
     CDS             2442..3113
                     /NRPS_PKS="Domain: PKS_KR (2-137). E-value: 1.2e-28. Score:
                     91.9. Matches aSDomain: nrpspksdomains_ctg44_2_PKS_KR.1"
                     /NRPS_PKS="type: other"
                     /locus_tag="ctg44_2"
                     /transl_table=11
                     /translation="LQQQITERGGEALIIQADVAQPKQLAEALALVETHWGQCHGLIHA
                     AGSAAQIACTDTTQATWDALMAAKLQGTQNLAMMVRPWKLDWAVVMSSLASDLGGLGFA
                     CYASANIAQHAIVHQLNQSSAVPWYCINWDGWQSADEADPQRLSFEQGWAALSAIVQQR
                     GVLNPQVVVGDVAARRQRWLYPQPTVAAPITTHRPRSANFEAPRSQLEQQLAAXXXXXX
                     A"
     aSDomain        2448..2852
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg44_2_PKS_KR.1"
                     /evalue="1.20E-28"
                     /label="ctg44_2_PKS_KR.1"
                     /locus_tag="ctg44_2"
                     /protein_end="137"
                     /protein_start="2"
                     /score="91.9"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: (unknown)"
                     /tool="antismash"
                     /translation="QQITERGGEALIIQADVAQPKQLAEALALVETHWGQCHGLIHAAG
                     SAAQIACTDTTQATWDALMAAKLQGTQNLAMMVRPWKLDWAVVMSSLASDLGGLGFACY
                     ASANIAQHAIVHQLNQSSAVPWYCINWDGWQS"
     aSModule        2448..2852
                     /domains="nrpspksdomains_ctg44_2_PKS_KR.1"
                     /incomplete
                     /locus_tags="ctg44_2"
                     /tool="antismash"
                     /type="unknown"
     CDS_motif       2694..2801
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg44_2_0001"
                     /evalue="1.40E-07"
                     /label="PKSI-KR_m4"
                     /locus_tag="ctg44_2"
                     /protein_end="120"
                     /protein_start="84"
                     /score="24.1"
                     /tool="antismash"
                     /translation="LDWAVVMSSLASDLGGLGFACYASANIAQHAIVHQLN"
     CDS             3340..3675
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Condensation"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg44_3"
                     /sec_met_domain="Condensation (E-value: 4.8e-10, bitscore:
                     26.6, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAVQALLEQLNALDIKLWLDGGNLRVNAPKGALTPELRAALSEQ
                     KPQLIAWFEHYQATANSNAAIQPSPRTTPLPLSFGQERLWFLDQLEGQSTAYNLSGCFE
                     IQGAFKPE"
ORIGIN
        1 attaataatg atggcgctca gaaagttggc tttaccgcac caagcatcaa gggtcaggcc
       61 caggttgtgg ccgaagcctt ggccttggcc gaagttgagc cgagcatggt tggctacctt
      121 gaaacccatg gcaccgcgac caaccttggc gatccaatcg agttagcagc gctcaaaaag
      181 gtttttgggg caactgctgc acaagcctgg tgcgccttag gcacgctcaa agctaatatt
      241 ggtcatctcg ataatgcggc tggggtggca ggcttgatca aaactgcctt ggcccttcat
      301 catcgccaac gaccaccaac cgcctatgcc accattccac atagcaattt gcaacaatca
      361 ccattttatt tgaacccgac tgcgagcgct tgggatgcaa atctttatgc tggagtcagt
      421 tcatttggca ttggcggtac gaatgcccat gtggtgctgg cggcagccga accaatcgcc
      481 aagcaagctc aggctgaatc atggcaattg ctgccaattt cggcggccag cgtttggtcg
      541 ctagagcagc aaaccgagcg gctggcggcg catctgcaaa ctaacccagc gcaatcgttg
      601 gctgatgtag cctataccct gcaaactgca cggcaagcct ttgctcaacg cagttttgtg
      661 gttgccaaaa gccatgaaca agccagccaa gccttgttga ccagcccaat ccgtgagttt
      721 gccagccaac cgcccaaggt tgcttggctc ttttcggggc agggcagcca atgtgctggg
      781 atggccgctg aactctatca gcaagcaccc gcttttcgcc aagcaattga tctggtgaat
      841 cgctatgctc aacccttact cggctacgat ctgcggcaaa tgatgttcga tcattcgggc
      901 gatctgacgg cgacgaacgt cgcgcagcca tgtttgttta tgctggaata tgccttggcg
      961 caacaatggt tggcgtgggg cattcaacca caagccttgt ttggccatag cattggcgaa
     1021 tatgtggccg cttgtgttgc caatgtgctg gatttaccga ctgctgtgcg cttggtggtg
     1081 gtgcgtggcc agttgatgaa ccaattgcct agcggagcga tgctcagcat taacgccagc
     1141 cgcgatcaga ttcagccaat cttgcctgct gaacttgatt tggcggcgat caataccaat
     1201 cagctgttgg tggtcgctgg tgagcatgtg gcgatccaag cctttcagca gcaattgaac
     1261 gagcgtggca tcgaatcacg catactgcac acctcgcatg cctttcattc gcgagcaatg
     1321 cagccgatgt tggcagcgtt tcgccagcac tttgccgatg tgcaacttca agcgccaacc
     1381 atcccgatcc tctcgaatgt gagtggtaca tggctgacgg cggtccaagc taccagtgtt
     1441 gactattggc ttgaacagat tgttaatcca gtgcagtgtg ctgcttgttt ggcccagttg
     1501 ttggccgatg atgcttggat tgtgcaggag cttgggcctg ggcatacgct ggcaaccttt
     1561 gcccgtgcca gccaggctgc tcaaacgccg ttgattctca ccagtttgcc gcatccacag
     1621 gttaagcaag ccgatttagc cgtgatgttg caaagtttag gtcaattgtg gcaagcaggc
     1681 atgacggtgc tgtggcaggc tctacatcaa acatcatgtc ataaagtttg gttgccaacc
     1741 tatgcgttcg atcaccaacg ccattggatt gaggcagaac aggcccacgc accccgcgca
     1801 agcaatcaaa taagcatcaa taccccaacc tggcaggctc aaagcttggc aaccacccca
     1861 atccaagcca gcacctggct ggtgtggggc agccaaccaa gcactatcga acggctgctc
     1921 gaacaatttg ccgccgatca gcagctctat atttgcaatc aagatacgtt tnnnnnnnnn
     1981 nnnnnnnnnn nnnnnnnnnn ngccgctgat ctgttgacga tcgccaagcg ggtgcgcgag
     2041 ttggggctag cccaggtaca tttgcatgtt gtaagcagcc agagtttggc gattgctccg
     2101 catgaagatc tcaacccgca tgatgctgca ttgcgcgggg tggcgatggt tttggcccaa
     2161 gaatatcccg aaatcagcag ccattggctt gaccttgatt ttacccatca agcgtggccg
     2221 agtatgttgg cccaagagct acaaagtgcc agcgagccag tggtggcatt gcgtggtttc
     2281 aatcggtttg tgccgcaggc cagggttgca agcttaccaa ccaatcagca gggcttcctc
     2341 gttggtggtt gctatttgat tacgggtggc aacggcggac tgggtcgtca aattgcgnnn
     2401 nnnnnnnnnn nntcgtgcct gagtcgcccg ctgcctatga tttgcaacag cagattaccg
     2461 aacgtggtgg tgaggcctta attattcagg ccgatgtggc acagcctaaa caattagccg
     2521 aagccttggc gctggtcgaa acccattggg gccaatgtca tggcctgatt cacgcagcgg
     2581 gcagtgccgc ccaaattgct tgtactgaca ccacccaagc aacttgggat gcgctgatgg
     2641 cggccaagct ccagggaacc caaaaccttg ccatgatggt gcggccttgg aaactcgatt
     2701 gggcggtggt gatgtcgtcg ttggccagtg atttgggtgg gctgggcttt gcctgctatg
     2761 ccagcgccaa cattgcccaa catgccatcg tgcatcaact caatcaatca agcgctgtac
     2821 cgtggtattg catcaactgg gatggttggc aaagcgccga tgaagccgat cctcaacgct
     2881 tgagctttga acaaggctgg gctgcgctaa gtgcgattgt ccaacaacgc ggcgtactca
     2941 acccgcaagt agttgtgggt gatgttgctg cacgtcgtca gcgctggctc tatccacaac
     3001 cgacagttgc tgcgccaatc acgacgcatc gtccacgttc agccaatttc gaggctccac
     3061 gcagccaact tgaacagcaa cttgcggcaa tnnnnnnnnn nnnnnnngcg taaacgaact
     3121 tagcattcat gataatttct tcgatttggg cggccattcg ttgttagcaa cccaagtgct
     3181 tggccgaatt cgtcagcaac ttcaacttga tctaccgcta cagctgcttt ttgaagcgcc
     3241 aacccttcaa ggcttggccg agcatattcg gcagcagcag cttagccaaa cgttacaagc
     3301 ccaagcagtt ggcggtggcg agcgtgagga gattgagtta tgagcgcggt tcaagcattg
     3361 ctcgaacaat taaatgcact cgacataaaa ttgtggctcg atgggggaaa tctgcgggta
     3421 aacgcaccta aaggggcatt aacacccgaa ttacgggctg cgctgagtga gcaaaaaccg
     3481 caattaattg cttggttcga gcactatcag gcgacggcca attcgaatgc agcgattcag
     3541 ccaagcccac gaactacgcc tttaccgctt tcctttggcc aagaacggct gtggtttctt
     3601 gaccaactcg aaggccaaag cactgcctac aatttgtcgg gctgttttga aattcagggc
     3661 gcgttcaagc ccgaatt
//
