LOCUS       c00426_3300014..        5496 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  3300014786.a:Ga0169450_105786.
ACCESSION   c00426_3300014..
VERSION     c00426_3300014..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 5.1.0
            Run date     :: 2019-11-23 08:11:54
            Original ID  :: 3300014786.a:Ga0169450_105786
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 5496
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..5496
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1:3925](-)"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(2..3925)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..5496
                     /SMILES="NC(C(C)C)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..5496
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="(cds(Condensation and (AMP-binding or A-OX)) or
                     (Condensation and AMP-binding))"
                     /tool="antismash"
     aSDomain        complement(2..586)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg426_1_Condensation_LCL.2"
                     /domain_subtype="Condensation_LCL"
                     /evalue="8.90E-58"
                     /label="ctg426_1_Condensation_LCL.2"
                     /locus_tag="ctg426_1"
                     /protein_end="1308"
                     /protein_start="1113"
                     /score="187.4"
                     /tool="antismash"
                     /translation="EHLPLSFAQERLWFLNQLDAXXXXNQAYTIPLAVRIVGDLPPAVI
                     QMALQQLVDRHSSLRTTFYALDGQPYQRIAPTLMLALSLHDLRGRSEADVHAAIHAAIA
                     EPFDLERGPLLRVTLLREADDRHVLVLTLHHSITDGWSMELLLREFAQALAAARLGEPT
                     RFAPLVVDVVDVVLWQRAVLRGERLAQLQGYW"
     aSModule        2..586
                     /domains="nrpspksdomains_ctg426_1_Condensation_LCL.2"
                     /incomplete
                     /locus_tags="ctg426_1"
                     /tool="antismash"
                     /type="nrps"
     CDS             complement(2..3925)
                     /NRPS_PKS="Domain: Condensation_LCL (53-358). E-value:
                     2.2e-100. Score: 327.3. Matches aSDomain:
                     nrpspksdomains_ctg426_1_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (522-921). E-value:
                     1.6e-111. Score: 364.5. Matches aSDomain:
                     nrpspksdomains_ctg426_1_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (1025-1093). E-value: 4.9e-21.
                     Score: 66.5. Matches aSDomain:
                     nrpspksdomains_ctg426_1_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (1113-1308). E-value:
                     8.9e-58. Score: 187.4. Matches aSDomain:
                     nrpspksdomains_ctg426_1_Condensation_LCL.2"
                     /NRPS_PKS="type: NRPS"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     169.7; E-value: 2.1e-51)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg426_1"
                     /sec_met_domain="Condensation (E-value: 1.1e-76, bitscore:
                     245.5, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 4.4e-117, bitscore:
                     378.7, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 2.3e-16, bitscore:
                     47.9, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEHSDDSLRNQTDPASRRVPLSAAKKARLEKRLRGDSDNQQAES
                     SIPRLATYDQVPLSFAQERLWFLSQYEPTSSNAYIIPLAVRIDGPIDPSLLEQALQLVV
                     DRHASFRTTFHAQNGVPFQRVAPQLPLRLPVLGLDVADASDEAAVLQVVLDQLVPLLQL
                     PFDLEHGPLLRATLLRLAAESHVLLLICHHIISDGWSMGVLLRDFASFLGALRTNTAPD
                     VPPLVVQAPDVAVWQRQRLQGHYLTTLQDFWKQQLADLEPLNVPTDFVRPAQQSYRGAT
                     LSFQLPAALSTQLQRMAQQHDVTPFMLLLAAFQAFLARLSGQQDLAIGSVLASRADADL
                     DPVIGFLVNTWTLRNNIDVAQPLAQLLPTVRRTVLAAFEHRDLPFEQVVQLVQPERDLS
                     RSPVFQVMMTYQNVPQRQMEWGDVRLTPISLPSTVAKFDLTLALSETPEGFRGVMEYRS
                     DLFRRSTIATMVARWEMFLHGIVADFTTSIARLPLVLPAERSLLLDTLNATTTAYPHDQ
                     SVASLFAEQARLWPERIALRFGEHSLSYHALEQRANQLAHHLQLLGVGPEHVVGLCVER
                     SLDLVVAILAILKAGAAYAPVDPSYPVERLAWMLSDLQPTVVIAQHGVLDRLPSVACSV
                     VVLETIAAHLAAYPTTAPTVDISPENLAYVMYTSGSTGRPKGIMINQRNIVRLVRNTTY
                     AAFGPDQVGLLLATVAFDASTFELWGCLLNGGRLVIAPPQQLSLAELGHLVEREQITTL
                     WLTAGLFHQMVDHALDRLGSLRQLLAGGDRLSPVHVHKVLERWPQCRLINGYGPTENTT
                     FSCCQQLSATTDLAQGVPIGQPIANSTAYILDRLLQLVPIGVVGELYLGGAGLARGYLA
                     RPDQTAAAFIPNPMSQTAGERLYRSGDLARYRDDGTIEFIGRRDQQVKVRGYRIELEEI
                     VGVLLAQPQVDDAVVVVREDRVGDQRLVAYLVGDNPAIELIEQAVQGQVPSYMLPSAYV
                     VLDALPLTANGKVDRRRLPAPSYAAIANDDPPQTDLEQAIAAIWAEVLAVPSIQRQTNF
                     FQVGGHSLLATQVVARVRELLPTVDLPVRRLFELPTLAAFVASLDPTPHKDAAVVLPAL
                     VAQPRPEHLPLSFAQERLWFLNQLDAXXXXNQAYTIPLAVRIVGDLPPAVIQMALQQLV
                     DRHSSLRTTFYALDGQPYQRIAPTLMLALSLHDLRGRSEADVHAAIHAAIAEPFDLERG
                     PLLRVTLLREADDRHVLVLTLHHSITDGWSMELLLREFAQALAAARLGEPTRFAPLVVD
                     VVDVVLWQRAVLRGERLAQLQGYW"
     CDS_motif       complement(128..190)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg426_1_0014"
                     /evalue="1.50E-09"
                     /label="C3_LCL_132-143"
                     /locus_tag="ctg426_1"
                     /protein_end="1266"
                     /protein_start="1245"
                     /score="30.3"
                     /tool="antismash"
                     /translation="LHHSITDGWSMELLLREFAQAL"
     CDS_motif       complement(398..508)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg426_1_0013"
                     /evalue="5.50E-14"
                     /label="C2_LCL_024-062"
                     /locus_tag="ctg426_1"
                     /protein_end="1176"
                     /protein_start="1139"
                     /score="44.5"
                     /tool="antismash"
                     /translation="AYTIPLAVRIVGDLPPAVIQMALQQLVDRHSSLRTTFY"
     CDS_motif       complement(539..571)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg426_1_0012"
                     /evalue="3.80E-03"
                     /label="C1_LCL_004-017"
                     /locus_tag="ctg426_1"
                     /protein_end="1129"
                     /protein_start="1118"
                     /score="9.9"
                     /tool="antismash"
                     /translation="SFAQERLWFLNQ"
     aSDomain        complement(647..850)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg426_1_PCP.1"
                     /evalue="4.90E-21"
                     /label="ctg426_1_PCP.1"
                     /locus_tag="ctg426_1"
                     /protein_end="1093"
                     /protein_start="1025"
                     /score="66.5"
                     /tool="antismash"
                     /translation="EQAIAAIWAEVLAVPSIQRQTNFFQVGGHSLLATQVVARVRELLP
                     TVDLPVRRLFELPTLAAFVASLDP"
     aSModule        647..3766
                     /complete
                     /domains="nrpspksdomains_ctg426_1_Condensation_LCL.1"
                     /domains="nrpspksdomains_ctg426_1_AMP-binding.1"
                     /domains="nrpspksdomains_ctg426_1_PCP.1"
                     /locus_tags="ctg426_1"
                     /monomer_pairings="val -> val"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(812..844)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg426_1_0011"
                     /evalue="1.70E+00"
                     /label="Cy4"
                     /locus_tag="ctg426_1"
                     /protein_end="1038"
                     /protein_start="1027"
                     /score="2.0"
                     /tool="antismash"
                     /translation="AIAAIWAEVLAV"
     CDS_motif       complement(1136..1198)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg426_1_0010"
                     /evalue="4.50E-10"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg426_1"
                     /protein_end="930"
                     /protein_start="909"
                     /score="31.6"
                     /tool="antismash"
                     /translation="FIGRRDQQVKVRGYRIELEEIV"
     aSDomain        complement(1163..2359)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg426_1_AMP-binding.1"
                     /evalue="1.60E-111"
                     /label="ctg426_1_AMP-binding.1"
                     /locus_tag="ctg426_1"
                     /protein_end="921"
                     /protein_start="522"
                     /score="364.5"
                     /specificity="consensus: val"
                     /tool="antismash"
                     /translation="FAEQARLWPERIALRFGEHSLSYHALEQRANQLAHHLQLLGVGPE
                     HVVGLCVERSLDLVVAILAILKAGAAYAPVDPSYPVERLAWMLSDLQPTVVIAQHGVLD
                     RLPSVACSVVVLETIAAHLAAYPTTAPTVDISPENLAYVMYTSGSTGRPKGIMINQRNI
                     VRLVRNTTYAAFGPDQVGLLLATVAFDASTFELWGCLLNGGRLVIAPPQQLSLAELGHL
                     VEREQITTLWLTAGLFHQMVDHALDRLGSLRQLLAGGDRLSPVHVHKVLERWPQCRLIN
                     GYGPTENTTFSCCQQLSATTDLAQGVPIGQPIANSTAYILDRLLQLVPIGVVGELYLGG
                     AGLARGYLARPDQTAAAFIPNPMSQTAGERLYRSGDLARYRDDGTIEFIGRRDQQVKVR
                     G"
     CDS_motif       complement(1286..1375)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg426_1_0009"
                     /evalue="1.10E-16"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg426_1"
                     /protein_end="880"
                     /protein_start="850"
                     /score="52.8"
                     /tool="antismash"
                     /translation="PIGVVGELYLGGAGLARGYLARPDQTAAAFI"
     CDS_motif       complement(1883..1939)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg426_1_0008"
                     /evalue="1.60E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg426_1"
                     /protein_end="681"
                     /protein_start="662"
                     /score="29.7"
                     /tool="antismash"
                     /translation="AYVMYTSGSTGRPKGIMINQ"
     CDS_motif       complement(2132..2173)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg426_1_0007"
                     /evalue="8.50E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg426_1"
                     /protein_end="598"
                     /protein_start="584"
                     /score="15.8"
                     /tool="antismash"
                     /translation="LAILKAGAAYAPVDP"
     CDS_motif       complement(2696..2815)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg426_1_0006"
                     /evalue="1.10E-21"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="ctg426_1"
                     /protein_end="410"
                     /protein_start="370"
                     /score="69.3"
                     /tool="antismash"
                     /translation="RRTVLAAFEHRDLPFEQVVQLVQPERDLSRSPVFQVMMTYQ"
     aSDomain        complement(2852..3766)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg426_1_Condensation_LCL.1"
                     /domain_subtype="Condensation_LCL"
                     /evalue="2.20E-100"
                     /label="ctg426_1_Condensation_LCL.1"
                     /locus_tag="ctg426_1"
                     /protein_end="358"
                     /protein_start="53"
                     /score="327.3"
                     /tool="antismash"
                     /translation="DQVPLSFAQERLWFLSQYEPTSSNAYIIPLAVRIDGPIDPSLLEQ
                     ALQLVVDRHASFRTTFHAQNGVPFQRVAPQLPLRLPVLGLDVADASDEAAVLQVVLDQL
                     VPLLQLPFDLEHGPLLRATLLRLAAESHVLLLICHHIISDGWSMGVLLRDFASFLGALR
                     TNTAPDVPPLVVQAPDVAVWQRQRLQGHYLTTLQDFWKQQLADLEPLNVPTDFVRPAQQ
                     SYRGATLSFQLPAALSTQLQRMAQQHDVTPFMLLLAAFQAFLARLSGQQDLAIGSVLAS
                     RADADLDPVIGFLVNTWTLRNNIDV"
     CDS_motif       complement(2864..2953)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg426_1_0005"
                     /evalue="3.30E-09"
                     /label="C5_LCL_267-296"
                     /locus_tag="ctg426_1"
                     /protein_end="354"
                     /protein_start="324"
                     /score="29.2"
                     /tool="antismash"
                     /translation="DLAIGSVLASRADADLDPVIGFLVNTWTLRN"
     CDS_motif       complement(2963..3019)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg426_1_0004"
                     /evalue="7.00E-03"
                     /label="Cy4"
                     /locus_tag="ctg426_1"
                     /protein_end="321"
                     /protein_start="302"
                     /score="9.5"
                     /tool="antismash"
                     /translation="VTPFMLLLAAFQAFLARLSG"
     CDS_motif       complement(3293..3355)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg426_1_0003"
                     /evalue="2.90E-11"
                     /label="C3_LCL_132-143"
                     /locus_tag="ctg426_1"
                     /protein_end="211"
                     /protein_start="190"
                     /score="35.8"
                     /tool="antismash"
                     /translation="CHHIISDGWSMGVLLRDFASFL"
     CDS_motif       complement(3581..3694)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg426_1_0002"
                     /evalue="1.00E-18"
                     /label="C2_LCL_024-062"
                     /locus_tag="ctg426_1"
                     /protein_end="115"
                     /protein_start="77"
                     /score="59.7"
                     /tool="antismash"
                     /translation="AYIIPLAVRIDGPIDPSLLEQALQLVVDRHASFRTTFHA"
     CDS_motif       complement(3722..3751)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg426_1_0001"
                     /evalue="5.20E-03"
                     /label="C1_LCL_004-017"
                     /locus_tag="ctg426_1"
                     /protein_end="68"
                     /protein_start="58"
                     /score="9.5"
                     /tool="antismash"
                     /translation="SFAQERLWFLS"
     CDS             complement(4169..5116)
                     /locus_tag="ctg426_2"
                     /transl_table=11
                     /translation="MDKNLVYTEGYCIDLFSRGLINLHLPYSNKIGLIIEKTDAEHLDV
                     VFNILNTVRAVYGVNIEEFVITDEAIGGRCIQHSSGSYVGSIDNPATLFRACEQLIAKG
                     VTAIAVTSNIQDLPADSYAEHFSGRHPNPVGGAEAIISHLIAKKYRLPAAHAPMINLKQ
                     IDLEDPIVDARGAGEITSHSGMASVLIGLAQAPQITARPTCRIADTININNVVAVVTPA
                     SALGGIPVLYAQKFNIPVIAVHNNATILEITPDRFPLNTVIEVQNYAEAAGIIMALKRG
                     LNLKSILRPLETLRYQRQAVATTVVNDAMIAELA"
     CDS             complement(5136..5495)
                     /locus_tag="ctg426_3"
                     /transl_table=11
                     /translation="SMIHNQEFIIRKSDIANPQSLPELIETLVSGDVLRWYVSKVTADE
                     LVVEATLYSEHLADPPESVLGQFYPGKSAVLNIVPTGVGCDXXXXXXXXXXXXXXXXXX
                     VGQLLRLFSDKSQCS"
ORIGIN
        1 gccaataccc ctgcaattgg gccaagcgct cgccacgcaa taccgctcgt tgccacagca
       61 cgacatcgac cacatcgacc accagcgggg caaaacgggt cggttcacca aggcgagcag
      121 cggccaaggc ttgggcaaat tcacgtaaca atagctccat cgaccagcca tcagtgatgc
      181 tatggtgcaa agtcagcacc aacacatggc gatcatcagc ttcgcgcagc aacgttaccc
      241 gcaatagcgg cccgcgctcc aaatcaaatg gttcggcaat tgccgcgtga atcgccgcat
      301 gcacgtcggc ttcgctccga ccacgcagat cgtgtaacga caacgctagc atgagggtcg
      361 gcgcaatccg ttgatagggc tgaccatcaa gtgcataaaa ggttgtgcgc aaactggaat
      421 gccgatctac cagctgttgt aaggccatct ggatcaccgc tggcggcagg tcgccaacaa
      481 tgcgcactgc cagcggaatc gtataggctt gattgnnnnn nnnnntcgca tcaagttggt
      541 tcaaaaacca caaacgttct tgggcaaacg ataatggaag atgttccggt cgtggttgtg
      601 ccaccagagc aggtagcacc acagcagcat ctttatgcgg tgttgggtcg agactagcca
      661 caaacgctgc caaggtcggt agctcaaaaa ggcggcgcac aggcagatca accgttggca
      721 gcagttcacg cacccgcgcc acaacttggg tagccaacaa cgaatgccca cctacttgga
      781 aaaagttggt ctggcgttga atgctcggca ccgccaagac ctcggcccaa atcgccgcta
      841 tcgcctgctc taaatcggtt tgtggcggat catcgttcgc gatggcggca tagctcggcg
      901 ctggcaaccg ccgccgatca accttgccat tcgccgtcaa cggcaaggca tcaagcacaa
      961 cataggcact cgggagcata tagctcggga cctggccttg caccgcttgt tcaatcagct
     1021 caatcgccgg attgtcaccc accagatagg ccaccaagcg ctgatcacca acccgatcct
     1081 cccgcaccac caccaccgca tcatccacct gtggttgtgc cagcaacacg ccaacgattt
     1141 cttccagctc aatccgatac ccgcgtacct tgacttgctg atcccgtcgt ccaataaatt
     1201 cgatcgtccc atcatcgcga taccgcgcca gatcccccga gcgatacagg cgttcgcccg
     1261 ccgtttggct catggggttc gggataaatg ccgccgccgt ctggtctgga cgcgctaaat
     1321 accctcgcgc taagcctgcg ccacccaaat acagttcgcc tacaacccct atgggaacca
     1381 gttgcaacaa ccggtcaaga atataggccg tgctgttcgc aatcggctgc ccaatcggca
     1441 cgccctgcgc caggtcagtg gttgcactaa gctgctgaca acagctaaat gtggtgtttt
     1501 ccgttgggcc atacccatta atcaggcgac actgcggcca gcgttccagc actttgtgta
     1561 catgcacggg cgacagtcga tcgccaccgg ccagtaattg acgcaacgaa cccaatcgat
     1621 ccagcgcatg atccaccatt tgatggaaca atccggcggt caaccagagc gtcgtaatct
     1681 gttcgcgctc caccaagtgg cccaattcgg caaggctgag ttgctgcggt ggggcgatca
     1741 ctaagcgtcc accattcagc aaacaccccc aaagttcgaa cgtcgaagca tcaaatgcca
     1801 ctgttgccag caataaccca acctggtctg gcccaaatgc cgcatacgtg gtgttgcgga
     1861 ccaatcgcac aatgttccgc tgattgatca taatcccttt gggtcggcct gttgaaccag
     1921 aggtatacat cacataggcc aaattttcgg ggctgatgtc cacggttggc gcagtcgtgg
     1981 gatacgctgc gaggtgcgcg gctatggttt caagcacaac cacggaacac gcaaccgacg
     2041 gtaagcggtc gagcacgccg tgctgtgcaa tcaccaccgt tggctgtaaa tcactcagca
     2101 tccaggccaa acgctcaacg ggataactcg gatcgaccgg ggcataggct gcgccagcct
     2161 tgagaatcgc cagaatcgcc accactaagt ccaacgagcg ctcaacacac aaaccaacca
     2221 catgctctgg cccaacaccc agcagttgca gatggtgcgc tagctggttg gcccgttgct
     2281 caagcgcgtg atagctgagg ctgtgctcac caaaacgaag cgcaatccgc tccggccaca
     2341 ggcgggcttg ttcggcaaac aaacttgcta cgctttgatc gtgtgggtag gcggttgtgg
     2401 tcgcattcaa cgtatcaagc aataagctgc gttccgcagg caagaccaac ggcaatcggg
     2461 caatggacgt ggtaaagtct gccacaatcc cgtgtaaaaa catttcccaa cgcgcaacca
     2521 tcgtggcaat cgtgctgcgc cgaaataaat cgctccgata ttccatcacc ccacgaaaac
     2581 cctcgggggt ttcgctcagc gccagagtta ggtcgaattt cgccaccgtg ctgggcaggc
     2641 taatcggggt caaccgaaca tccccccatt ccatctgccg ttgcggcacg ttttgatagg
     2701 tcatcatcac ctgaaacacg ggcgaacggc tcagatcacg ctccggttgc accagttgca
     2761 ccacctgctc aaacggtaaa tcgcggtgct caaacgctgc caggacggta cgtcgcaccg
     2821 tgggcaagag ctgcgccaat ggctgcgcta catctatgtt gttccgcaac gtccaggtat
     2881 tcaccaaaaa accaatcacc ggatcaaggt cagcatcggc ccgactcgct agcacggaac
     2941 caatcgccag atcctgttgc ccactcagtc gcgccaaaaa agcctgaaat gcggcaagca
     3001 gcagcataaa tggggtcaca tcatgctgtt gcgccatacg ctgaagctgg gtgctgagcg
     3061 cagcggggag ctgaaaactc aatgtcgccc cacgatagga ttgctgggcc ggtcggacaa
     3121 aatcggtagg cacattcaat ggttcgagat ccgccaactg ctgcttccaa aaatcttgga
     3181 gtgtcgtcag atagtggcct tgcaagcgtt gccgttgcca caccgcgaca tccggggctt
     3241 gcaccaccaa cggcggtaca tccggcgcag tattggtgcg taacgcgcct aaaaagctgg
     3301 caaaatcgcg cagcagcacc cccatcgacc agccatcact aataatatga tggcaaatca
     3361 gcagcagcac atgcgattcg gcagctaaac gcagtaaggt cgctcgcaac aacggcccat
     3421 gctcaagatc aaacggtagc tgcaacagcg gtacaagctg atccagcacg acctgcaaca
     3481 ccgccgcctc atcgctcgca tcagccacgt ccagcccaag cacgggcaac ctgagcggca
     3541 gctgtggggc aacccgttga aacggcaccc cattctgcgc atgaaacgtg gtgcggaagc
     3601 tggcatggcg atccaccacc aattgcaaag cctgctccaa cagcgatgga tcaatggggc
     3661 catcgatccg cacggccaag ggaataatat aggcgttgct gctcgttggt tcgtattggc
     3721 tgagaaacca cagccgttct tgcgcaaacg ataatggcac ctgatcatag gtcgcgaggc
     3781 gaggaatgct tgattcagcc tgctgattgt cgctatcacc gcgcaggcgt ttttcgagcc
     3841 gcgctttttt ggccgccgaa agcggaactc gccgagatgc aggatcagtc tggttgcgca
     3901 acgaatcatc tgaatgctca gacattattc acctcgtaat tgtttcaaac gcttctctag
     3961 gagtgaccgt ttatgttcgg ttgcaattgc gagcaattca ggctgatgct gcgtataacc
     4021 agtcaagcgc tggagcatat cgaattgatc aggttggtta gttggtgcaa ctagcgggag
     4081 tgctgaagga agttggtctg tcacagtcgg gtactccaag ctgggccgta ttgctacgac
     4141 ccagatccat cgttgccaac caaagatgtt aggctagttc agctatcatt gcatcgttta
     4201 cgacagtcgt agcgactgcc tgacgctgat agcgcaaggt ttccaacggt cgtaggatac
     4261 tcttcaagtt taggccacgc ttgagcgcca taataattcc ggcggcttca gcataatttt
     4321 gcacttcaat cacggtatta agcgggaagc gatcgggcgt aatctccaaa attgtggcat
     4381 tattgtgcac tgcaatcacg ggaatattaa atttttgggc atacaacacc ggaatgccac
     4441 ccaaggcact agcaggtgtc acaactgcca caacattatt aatattaatc gtgtcggcga
     4501 tgcggcaagt tggccgagcg gtaatttgcg gagcctgagc taagccaatt agcacgctcg
     4561 ccatcccact gtgcgaggta atttcgcctg cgccacgggc atcgacaatc ggatcttcaa
     4621 ggtcaatttg cttgaggtta atcatcgggg catgggcggc gggcaagcga tatttcttgg
     4681 cgatcaggtg cgagataatc gcctcggctc caccaactgg attgggatgt cggcccgaaa
     4741 agtgctcggc atagctatca gcaggcaaat cttggatgtt gctggtgact gcaattgcgg
     4801 ttacaccctt ggcgatcaat tgctcgcaag cacggaataa ggtcgccgga ttgtcgatac
     4861 tgccaacata gctgccagaa ctatgctgaa tacaacgccc accgatcgcc tcatcggtga
     4921 tcacaaactc ttcaatattc accccataaa ctgcgcgaac ggtattgaga atattaaaca
     4981 ccacatccaa gtgctcagca tcggtttttt cgataatcaa gccaatttta ttgctatatg
     5041 gcaggtgcag gttaatcaaa ccacgcgaga agagatcaat gcagtagcct tcggtataca
     5101 ctaaattttt atccatcaag ataaaatttg aagcattaac tgcattggga tttgtcacta
     5161 aataatcgca gcaactggcc aacagnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     5221 nnnnnnnnnn nnnnnatatc acaaccaact ccggttggca caatgttcaa cacagcgctc
     5281 ttgccagggt aaaactgccc aagcacactc tcgggcgggt cggccagatg ttcgctataa
     5341 agcgtggcct cgaccaccag ctcatcagcc gttactttag aaacatacca acgtaataca
     5401 tcgccactca ccagcgtttc gatcaattca ggcagacttt gtggattagc aatatcagat
     5461 ttacgaatga taaattcttg attgtgaatc atgctg
//
